locus-tag	class	description
BSY18_RS00065	COG1984	allophanate hydrolase subunit 2
BSY18_RS00110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY18_RS00130	COG3158	transport of potassium into the cell
BSY18_RS00160	COG0156	8-amino-7-oxononanoate synthase activity
BSY18_RS00305	COG0612	Peptidase, M16
BSY18_RS00395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSY18_RS00570	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS00600	COG1530	ribonuclease E activity
BSY18_RS00670	COG0651	ATP synthesis coupled electron transport
BSY18_RS00925	COG4774	siderophore transport
BSY18_RS00955	COG0657	acetylesterase activity
BSY18_RS00960	COG0625	glutathione transferase activity
BSY18_RS00985	COG1984	allophanate hydrolase subunit 2
BSY18_RS00995	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BSY18_RS01000	COG1914	H( )-stimulated, divalent metal cation uptake system
BSY18_RS01020	COG3156	type II secretion system protein K
BSY18_RS01035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY18_RS01040	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BSY18_RS01045	COG1138	Cytochrome C-type biogenesis protein
BSY18_RS01055	COG3088	subunit of a heme lyase
BSY18_RS01065	COG3158	transport of potassium into the cell
BSY18_RS01085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY18_RS01095	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BSY18_RS01100	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BSY18_RS01105	COG0156	8-amino-7-oxononanoate synthase activity
BSY18_RS01110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSY18_RS01115	COG0440	acetolactate synthase activity
BSY18_RS01120	COG0028	Belongs to the TPP enzyme family
BSY18_RS01125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSY18_RS01130	COG3830	Belongs to the UPF0237 family
BSY18_RS01130	COG0560	Phosphoserine phosphatase
BSY18_RS01135	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS01140	COG0745	RESPONSE REGULATOR receiver
BSY18_RS01145	COG0704	Plays a role in the regulation of phosphate uptake
BSY18_RS01150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSY18_RS01160	COG0573	inorganic phosphate transmembrane transporter activity
BSY18_RS01170	COG5002	protein histidine kinase activity
BSY18_RS01195	COG0546	phosphoglycolate phosphatase activity
BSY18_RS01200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY18_RS01210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY18_RS01220	COG5001	Diguanylate cyclase
BSY18_RS01220	COG1716	ATPase activity
BSY18_RS01225	COG0047	phosphoribosylformylglycinamidine synthase activity
BSY18_RS01235	COG0612	Peptidase, M16
BSY18_RS01240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY18_RS01245	COG1024	Enoyl-CoA hydratase
BSY18_RS01250	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BSY18_RS01255	COG5001	Diguanylate cyclase
BSY18_RS01260	COG0617	tRNA 3'-terminal CCA addition
BSY18_RS01290	COG2032	superoxide dismutase activity
BSY18_RS01315	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSY18_RS01320	COG1695	Transcriptional regulator
BSY18_RS01330	COG0156	8-amino-7-oxononanoate synthase activity
BSY18_RS01350	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSY18_RS01355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSY18_RS01360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY18_RS01365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSY18_RS01380	COG2119	membrane
BSY18_RS01390	COG0137	argininosuccinate synthase activity
BSY18_RS01420	COG2885	chlorophyll binding
BSY18_RS01425	COG0823	Involved in the tonB-independent uptake of proteins
BSY18_RS01445	COG0824	Thioesterase
BSY18_RS01450	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BSY18_RS01465	COG2205	protein histidine kinase activity
BSY18_RS01475	COG0745	RESPONSE REGULATOR receiver
BSY18_RS01490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSY18_RS01500	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSY18_RS01505	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY18_RS01515	COG1530	ribonuclease E activity
BSY18_RS01520	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSY18_RS01525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BSY18_RS01530	COG1959	2 iron, 2 sulfur cluster binding
BSY18_RS01535	COG3920	Histidine kinase
BSY18_RS01545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSY18_RS01565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY18_RS01570	COG2111	Na H antiporter
BSY18_RS01570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY18_RS01575	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY18_RS01580	COG0651	ATP synthesis coupled electron transport
BSY18_RS01585	COG1863	multisubunit Na H antiporter MnhE subunit
BSY18_RS01590	COG2212	antiporter activity
BSY18_RS01615	COG0436	Aminotransferase
BSY18_RS01620	COG3273	potassium ion transport
BSY18_RS01620	COG0471	metal ion transport
BSY18_RS01625	COG2205	protein histidine kinase activity
BSY18_RS01625	COG2198	Histidine kinase
BSY18_RS01625	COG0784	Response regulator, receiver
BSY18_RS01630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSY18_RS01640	COG2205	protein histidine kinase activity
BSY18_RS01640	COG2202	Pas domain
BSY18_RS01650	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS01660	COG4774	siderophore transport
BSY18_RS01665	COG0246	Mannitol dehydrogenase
BSY18_RS01670	COG1904	glucuronate isomerase
BSY18_RS01715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY18_RS01720	COG1846	Transcriptional regulator
BSY18_RS01725	COG2130	NADP-dependent
BSY18_RS01730	COG1024	Enoyl-CoA hydratase
BSY18_RS01735	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS01750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY18_RS01765	COG0066	3-isopropylmalate dehydratase activity
BSY18_RS01785	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSY18_RS01790	COG2962	Rard protein
BSY18_RS01810	COG0484	heat shock protein binding
BSY18_RS01825	COG3023	N-Acetylmuramoyl-L-alanine amidase
BSY18_RS01835	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSY18_RS01840	COG2201	protein-glutamate methylesterase activity
BSY18_RS01855	COG0643	Histidine kinase
BSY18_RS01855	COG2198	Histidine kinase
BSY18_RS01870	COG0564	pseudouridine synthase activity
BSY18_RS01875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY18_RS01885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSY18_RS01895	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BSY18_RS01915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS01935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSY18_RS01940	COG4206	TonB-dependent receptor
BSY18_RS01945	COG4221	oxidoreductase activity
BSY18_RS01950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BSY18_RS01955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSY18_RS01970	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS02005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY18_RS02010	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BSY18_RS02015	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSY18_RS02035	COG0456	acetyltransferase
BSY18_RS02035	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BSY18_RS02040	COG1611	Belongs to the LOG family
BSY18_RS02050	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSY18_RS02065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSY18_RS02090	COG0542	response to heat
BSY18_RS02100	COG2308	Evidence 4 Homologs of previously reported genes of
BSY18_RS02170	COG3104	oligopeptide transport
BSY18_RS02175	COG1228	amidohydrolase
BSY18_RS02180	COG1228	amidohydrolase
BSY18_RS02190	COG0667	Aldo Keto reductase
BSY18_RS02200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY18_RS02205	COG3813	Protein conserved in bacteria
BSY18_RS02210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BSY18_RS02210	COG0351	phosphomethylpyrimidine kinase
BSY18_RS02210	COG0352	thiamine-phosphate diphosphorylase activity
BSY18_RS02230	COG2917	probably involved in intracellular septation
BSY18_RS02235	COG0552	protein localization to endoplasmic reticulum
BSY18_RS02240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY18_RS02245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSY18_RS02250	COG5001	Diguanylate cyclase
BSY18_RS02250	COG3300	MHYT domain
BSY18_RS02255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSY18_RS02260	COG0228	four-way junction DNA binding
BSY18_RS02265	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSY18_RS02280	COG0336	Belongs to the RNA methyltransferase TrmD family
BSY18_RS02285	COG0335	large ribosomal subunit rRNA binding
BSY18_RS02290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSY18_RS02295	COG2814	Major facilitator Superfamily
BSY18_RS02300	COG1566	PFAM secretion protein HlyD family protein
BSY18_RS02330	COG0659	secondary active sulfate transmembrane transporter activity
BSY18_RS02340	COG0640	Transcriptional regulator
BSY18_RS02345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSY18_RS02355	COG0359	binds to the 23S rRNA
BSY18_RS02360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSY18_RS02365	COG0360	Binds together with S18 to 16S ribosomal RNA
BSY18_RS02370	COG2199	diguanylate cyclase activity
BSY18_RS02380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BSY18_RS02390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY18_RS02395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY18_RS02400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSY18_RS02430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY18_RS02455	COG0686	Belongs to the AlaDH PNT family
BSY18_RS02485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY18_RS02490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY18_RS02500	COG0513	Belongs to the DEAD box helicase family
BSY18_RS02515	COG2081	HI0933 family
BSY18_RS02520	COG2003	Belongs to the UPF0758 family
BSY18_RS02545	COG0356	it plays a direct role in the translocation of protons across the membrane
BSY18_RS02555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY18_RS02560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY18_RS02565	COG0322	excinuclease ABC activity
BSY18_RS02570	COG1381	Involved in DNA repair and RecF pathway recombination
BSY18_RS02575	COG0473	3-isopropylmalate dehydrogenase activity
BSY18_RS02585	COG0151	Belongs to the GarS family
BSY18_RS02590	COG1570	exodeoxyribonuclease VII activity
BSY18_RS02640	COG2255	four-way junction helicase activity
BSY18_RS02650	COG3609	addiction module antidote protein, CC2985 family
BSY18_RS02655	COG0632	four-way junction helicase activity
BSY18_RS02660	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSY18_RS02670	COG0217	transcriptional regulatory protein
BSY18_RS02680	COG3750	Belongs to the UPF0335 family
BSY18_RS02690	COG0469	pyruvate kinase activity
BSY18_RS02700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSY18_RS02710	COG2866	Carboxypeptidase
BSY18_RS02720	COG1301	dicarboxylic acid transport
BSY18_RS02725	COG0471	metal ion transport
BSY18_RS02725	COG3273	potassium ion transport
BSY18_RS02730	COG2814	Major facilitator Superfamily
BSY18_RS02735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSY18_RS02750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BSY18_RS02755	COG1295	ribonuclease BN
BSY18_RS02760	COG0484	heat shock protein binding
BSY18_RS02770	COG0259	pyridoxamine-phosphate oxidase activity
BSY18_RS02800	COG0482	sulfurtransferase activity
BSY18_RS02820	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY18_RS02825	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSY18_RS02830	COG0124	histidyl-tRNA synthetase
BSY18_RS02840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSY18_RS02850	COG0045	succinate-CoA ligase (ADP-forming) activity
BSY18_RS02855	COG2086	electron transfer activity
BSY18_RS02865	COG0138	bifunctional purine biosynthesis protein purh
BSY18_RS02875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSY18_RS02885	COG0501	Belongs to the peptidase M48B family
BSY18_RS02915	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BSY18_RS02925	COG0793	Belongs to the peptidase S41A family
BSY18_RS02935	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSY18_RS02940	COG0799	negative regulation of ribosome biogenesis
BSY18_RS02945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSY18_RS02960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSY18_RS02965	COG0739	heme binding
BSY18_RS02965	COG0741	lytic transglycosylase activity
BSY18_RS02965	COG1196	nuclear chromosome segregation
BSY18_RS03000	COG0321	lipoyl(octanoyl) transferase activity
BSY18_RS03010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSY18_RS03070	COG1842	Phage shock protein A
BSY18_RS03080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BSY18_RS03085	COG2850	peptidyl-arginine hydroxylation
BSY18_RS03095	COG1063	alcohol dehydrogenase
BSY18_RS03120	COG0626	cystathionine gamma-synthase activity
BSY18_RS03125	COG2897	thiosulfate sulfurtransferase activity
BSY18_RS03130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSY18_RS03160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY18_RS03165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSY18_RS03210	COG0028	Belongs to the TPP enzyme family
BSY18_RS03220	COG1051	belongs to the nudix hydrolase family
BSY18_RS03230	COG0657	acetylesterase activity
BSY18_RS03235	COG0674	pyruvate-flavodoxin oxidoreductase activity
BSY18_RS03235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BSY18_RS03240	COG1013	pyruvate-flavodoxin oxidoreductase activity
BSY18_RS03255	COG2311	Membrane
BSY18_RS03280	COG1271	oxidase subunit
BSY18_RS03300	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSY18_RS03305	COG0588	phosphoglycerate mutase activity
BSY18_RS03320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY18_RS03325	COG0564	pseudouridine synthase activity
BSY18_RS03335	COG1956	GAF domain-containing protein
BSY18_RS03370	COG3920	Histidine kinase
BSY18_RS03375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY18_RS03390	COG0037	tRNA processing
BSY18_RS03410	COG1758	RNA polymerase activity
BSY18_RS03415	COG0275	rRNA processing
BSY18_RS03420	COG2329	Antibiotic biosynthesis monooxygenase
BSY18_RS03440	COG1494	fructose-1,6-bisphosphatase
BSY18_RS03455	COG2354	Protein conserved in bacteria
BSY18_RS03470	COG0681	Belongs to the peptidase S26 family
BSY18_RS03475	COG0736	holo-[acyl-carrier-protein] synthase activity
BSY18_RS03480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSY18_RS03490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSY18_RS03495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY18_RS03500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY18_RS03505	COG0109	protoheme IX farnesyltransferase activity
BSY18_RS03510	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSY18_RS03555	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY18_RS03600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY18_RS03610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSY18_RS03615	COG0416	fatty acid biosynthetic process
BSY18_RS03620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSY18_RS03625	COG0776	regulation of translation
BSY18_RS03645	COG1199	ATP-dependent helicase activity
BSY18_RS03650	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BSY18_RS03660	COG0598	Magnesium transport protein CorA
BSY18_RS03665	COG0693	protein deglycase activity
BSY18_RS03680	COG3876	Protein conserved in bacteria
BSY18_RS03705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY18_RS03715	COG1610	YqeY-like protein
BSY18_RS03720	COG0505	Belongs to the CarA family
BSY18_RS03735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY18_RS03765	COG0148	phosphopyruvate hydratase activity
BSY18_RS03775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY18_RS03780	COG0022	dehydrogenase e1 component
BSY18_RS03780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY18_RS03810	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BSY18_RS03840	COG3022	response to hydroperoxide
BSY18_RS03850	COG1522	sequence-specific DNA binding
BSY18_RS03855	COG2205	protein histidine kinase activity
BSY18_RS03890	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY18_RS03895	COG0303	'Molybdopterin
BSY18_RS03900	COG0315	cyclic pyranopterin monophosphate synthase activity
BSY18_RS03905	COG0134	indole-3-glycerol-phosphate synthase activity
BSY18_RS03910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSY18_RS03920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BSY18_RS03930	COG0149	triose-phosphate isomerase activity
BSY18_RS03935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY18_RS03940	COG0504	CTP synthase activity
BSY18_RS03950	COG0071	Belongs to the small heat shock protein (HSP20) family
BSY18_RS03960	COG1136	(ABC) transporter
BSY18_RS03965	COG0386	Belongs to the glutathione peroxidase family
BSY18_RS03980	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS03995	COG1040	competence protein
BSY18_RS04000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSY18_RS04090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY18_RS04095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BSY18_RS04100	COG2080	2 iron, 2 sulfur cluster binding
BSY18_RS04130	COG0385	Bile acid
BSY18_RS04135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSY18_RS04160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BSY18_RS04170	COG0402	S-adenosylhomocysteine deaminase activity
BSY18_RS04175	COG1846	Transcriptional regulator
BSY18_RS04185	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04190	COG0251	oxidation-reduction process
BSY18_RS04200	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04205	COG1024	Enoyl-CoA hydratase
BSY18_RS04210	COG1846	Transcriptional regulator
BSY18_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04225	COG0436	Aminotransferase
BSY18_RS04255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY18_RS04260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY18_RS04265	COG0583	DNA-binding transcription factor activity
BSY18_RS04270	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSY18_RS04285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSY18_RS04290	COG0402	S-adenosylhomocysteine deaminase activity
BSY18_RS04300	COG4771	TonB-dependent receptor
BSY18_RS04325	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BSY18_RS04330	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY18_RS04335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSY18_RS04340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY18_RS04345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSY18_RS04350	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY18_RS04365	COG0105	UTP biosynthetic process
BSY18_RS04375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSY18_RS04380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSY18_RS04395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BSY18_RS04405	COG1045	serine acetyltransferase
BSY18_RS04420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BSY18_RS04425	COG0583	DNA-binding transcription factor activity
BSY18_RS04430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BSY18_RS04445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSY18_RS04505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY18_RS04520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BSY18_RS04525	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY18_RS04545	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04555	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04560	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS04590	COG0427	acetyl-CoA hydrolase
BSY18_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04620	COG4638	Rieske (2fe-2S)
BSY18_RS04730	COG0028	Belongs to the TPP enzyme family
BSY18_RS04740	COG2072	flavoprotein involved in K transport
BSY18_RS04745	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04755	COG1902	pentaerythritol trinitrate reductase activity
BSY18_RS04790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY18_RS04815	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS04820	COG1024	Enoyl-CoA hydratase
BSY18_RS04825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS04840	COG0604	alcohol dehydrogenase
BSY18_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04870	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04875	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS04885	COG1024	Enoyl-CoA hydratase
BSY18_RS04890	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS04930	COG1063	alcohol dehydrogenase
BSY18_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS04960	COG4638	Rieske (2fe-2S)
BSY18_RS04970	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS04985	COG0183	Belongs to the thiolase family
BSY18_RS04995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY18_RS05005	COG2814	Major facilitator Superfamily
BSY18_RS05015	COG5016	pyruvate
BSY18_RS05015	COG0511	ligase activity, forming carbon-carbon bonds
BSY18_RS05025	COG0657	acetylesterase activity
BSY18_RS05030	COG1024	Enoyl-CoA hydratase
BSY18_RS05035	COG1053	succinate dehydrogenase
BSY18_RS05045	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY18_RS05050	COG0022	dehydrogenase e1 component
BSY18_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS05070	COG1063	alcohol dehydrogenase
BSY18_RS05100	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSY18_RS05125	COG0628	permease
BSY18_RS05165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSY18_RS05170	COG0126	phosphoglycerate kinase activity
BSY18_RS05175	COG3588	fructose-bisphosphate aldolase
BSY18_RS05180	COG0352	thiamine-phosphate diphosphorylase activity
BSY18_RS05185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSY18_RS05190	COG0483	inositol monophosphate 1-phosphatase activity
BSY18_RS05200	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY18_RS05205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY18_RS05210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY18_RS05215	COG0649	NAD binding
BSY18_RS05230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSY18_RS05240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSY18_RS05245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY18_RS05255	COG0713	ATP synthesis coupled electron transport
BSY18_RS05270	COG1007	ATP synthesis coupled electron transport
BSY18_RS05280	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSY18_RS05295	COG1278	Cold shock
BSY18_RS05305	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSY18_RS05315	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSY18_RS05325	COG1420	regulation of RNA biosynthetic process
BSY18_RS05330	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSY18_RS05340	COG2847	Copper chaperone PCu(A)C
BSY18_RS05345	COG0443	Heat shock 70 kDa protein
BSY18_RS05350	COG0484	heat shock protein binding
BSY18_RS05360	COG0235	Class ii aldolase
BSY18_RS05370	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSY18_RS05375	COG0545	Peptidyl-prolyl cis-trans isomerase
BSY18_RS05390	COG0006	proline dipeptidase activity
BSY18_RS05440	COG0668	transmembrane transport
BSY18_RS05450	COG0183	Belongs to the thiolase family
BSY18_RS05460	COG4948	Mandelate Racemase Muconate Lactonizing
BSY18_RS05470	COG1132	(ABC) transporter
BSY18_RS05480	COG0251	oxidation-reduction process
BSY18_RS05485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSY18_RS05490	COG0590	tRNA wobble adenosine to inosine editing
BSY18_RS05500	COG3279	Response regulator of the LytR AlgR family
BSY18_RS05505	COG2972	Histidine kinase
BSY18_RS05530	COG0501	Belongs to the peptidase M48B family
BSY18_RS05540	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSY18_RS05550	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSY18_RS05565	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BSY18_RS05585	COG0625	glutathione transferase activity
BSY18_RS05605	COG2945	thiolester hydrolase activity
BSY18_RS05610	COG1104	cysteine desulfurase activity
BSY18_RS05635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BSY18_RS05640	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSY18_RS05650	COG0776	regulation of translation
BSY18_RS05670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY18_RS05680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY18_RS05685	COG0183	Belongs to the thiolase family
BSY18_RS05690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY18_RS05695	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BSY18_RS05700	COG1252	NADH dehydrogenase
BSY18_RS05715	COG3263	regulation of cellular component size
BSY18_RS05720	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSY18_RS05735	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BSY18_RS05735	COG0644	oxidoreductase
BSY18_RS05740	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSY18_RS05750	COG0129	dihydroxy-acid dehydratase activity
BSY18_RS05760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSY18_RS05760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSY18_RS05765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSY18_RS05790	COG1748	Saccharopine dehydrogenase
BSY18_RS05800	COG1595	DNA-templated transcription, initiation
BSY18_RS05810	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY18_RS05820	COG4106	trans-aconitate 2-methyltransferase activity
BSY18_RS05825	COG1793	dna ligase
BSY18_RS05835	COG3038	cytochrome b561
BSY18_RS05840	COG0156	8-amino-7-oxononanoate synthase activity
BSY18_RS05845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSY18_RS05850	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSY18_RS05855	COG0758	DNA mediated transformation
BSY18_RS05860	COG1754	DNA topoisomerase type I activity
BSY18_RS05860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSY18_RS05870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSY18_RS05875	COG0571	ribonuclease III activity
BSY18_RS05880	COG0681	Belongs to the peptidase S26 family
BSY18_RS05885	COG0166	Belongs to the GPI family
BSY18_RS05895	COG1396	sequence-specific DNA binding
BSY18_RS05895	COG3800	Transcriptional regulator
BSY18_RS05900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY18_RS05905	COG0346	lactoylglutathione lyase activity
BSY18_RS05910	COG1024	Enoyl-CoA hydratase
BSY18_RS05915	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSY18_RS05915	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSY18_RS05920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BSY18_RS05930	COG4770	biotin carboxylase activity
BSY18_RS05940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSY18_RS05955	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BSY18_RS05960	COG0442	prolyl-tRNA aminoacylation
BSY18_RS05965	COG0557	exoribonuclease II activity
BSY18_RS05975	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY18_RS05980	COG2852	Protein conserved in bacteria
BSY18_RS05990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY18_RS06000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BSY18_RS06030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY18_RS06040	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSY18_RS06045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSY18_RS06060	COG4974	Belongs to the 'phage' integrase family
BSY18_RS06065	COG0825	malonyl-CoA metabolic process
BSY18_RS06070	COG0501	Belongs to the peptidase M48B family
BSY18_RS06115	COG0596	Alpha beta hydrolase
BSY18_RS06155	COG1462	curli production assembly transport component CsgG
BSY18_RS06170	COG2951	lytic endotransglycosylase activity
BSY18_RS06180	COG1686	Belongs to the peptidase S11 family
BSY18_RS06185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSY18_RS06200	COG0084	hydrolase, TatD family'
BSY18_RS06205	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BSY18_RS06205	COG0321	lipoyl(octanoyl) transferase activity
BSY18_RS06215	COG3956	TIGRFAM MazG family protein
BSY18_RS06220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSY18_RS06225	COG1923	regulation of RNA biosynthetic process
BSY18_RS06230	COG2204	response regulator
BSY18_RS06235	COG5000	phosphorelay sensor kinase activity
BSY18_RS06240	COG2204	response regulator
BSY18_RS06255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSY18_RS06255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSY18_RS06265	COG1546	Belongs to the CinA family
BSY18_RS06265	COG1058	Belongs to the CinA family
BSY18_RS06275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSY18_RS06280	COG0259	pyridoxamine-phosphate oxidase activity
BSY18_RS06300	COG0583	DNA-binding transcription factor activity
BSY18_RS06305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSY18_RS06305	COG0519	Catalyzes the synthesis of GMP from XMP
BSY18_RS06310	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS06335	COG2814	Major facilitator Superfamily
BSY18_RS06340	COG0531	amino acid
BSY18_RS06355	COG0140	phosphoribosyl-ATP diphosphatase activity
BSY18_RS06365	COG0107	imidazoleglycerol-phosphate synthase activity
BSY18_RS06370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSY18_RS06375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BSY18_RS06380	COG0131	Imidazoleglycerol-phosphate dehydratase
BSY18_RS06390	COG0114	fumarate hydratase activity
BSY18_RS06400	COG0194	GDP metabolic process
BSY18_RS06415	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS06420	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS06425	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS06430	COG2211	Major facilitator Superfamily
BSY18_RS06435	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS06465	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY18_RS06465	COG1024	Enoyl-CoA hydratase
BSY18_RS06485	COG0546	phosphoglycolate phosphatase activity
BSY18_RS06495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSY18_RS06505	COG0616	signal peptide processing
BSY18_RS06530	COG3220	belongs to the UPF0276 family
BSY18_RS06540	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSY18_RS06545	COG0459	protein refolding
BSY18_RS06565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY18_RS06565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BSY18_RS06575	COG0077	Prephenate dehydratase
BSY18_RS06580	COG3474	cytochrome
BSY18_RS06610	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY18_RS06610	COG1648	precorrin-2 dehydrogenase activity
BSY18_RS06615	COG0019	diaminopimelate decarboxylase activity
BSY18_RS06625	COG0165	Argininosuccinate lyase
BSY18_RS06630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY18_RS06645	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BSY18_RS06650	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSY18_RS06655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY18_RS06660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSY18_RS06665	COG0586	Pfam SNARE associated Golgi protein
BSY18_RS06670	COG0189	ligase activity
BSY18_RS06675	COG0792	nuclease activity
BSY18_RS06680	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSY18_RS06690	COG1024	Enoyl-CoA hydratase
BSY18_RS06715	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSY18_RS06750	COG1393	Belongs to the ArsC family
BSY18_RS06760	COG0584	glycerophosphoryl diester phosphodiesterase
BSY18_RS06770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSY18_RS06775	COG0183	Belongs to the thiolase family
BSY18_RS06790	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY18_RS06795	COG4771	TonB-dependent receptor
BSY18_RS06810	COG0277	FAD linked oxidase domain protein
BSY18_RS06820	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS06835	COG0784	Response regulator, receiver
BSY18_RS06870	COG1230	cation diffusion facilitator family transporter
BSY18_RS06875	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSY18_RS06885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSY18_RS06895	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSY18_RS06905	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSY18_RS06915	COG0653	protein targeting
BSY18_RS06945	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY18_RS06945	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY18_RS06955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSY18_RS06960	COG0193	aminoacyl-tRNA hydrolase activity
BSY18_RS06985	COG0012	GTP binding
BSY18_RS06990	COG3540	Alkaline phosphatase
BSY18_RS07000	COG2030	dehydratase
BSY18_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS07010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSY18_RS07030	COG0768	penicillin binding
BSY18_RS07035	COG0772	Belongs to the SEDS family
BSY18_RS07050	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSY18_RS07065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSY18_RS07070	COG1845	cytochrome c oxidase, subunit III
BSY18_RS07075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY18_RS07080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY18_RS07085	COG0477	Major facilitator Superfamily
BSY18_RS07125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY18_RS07130	COG0004	ammonium transporteR
BSY18_RS07135	COG0481	GTPase activity
BSY18_RS07140	COG4206	TonB-dependent receptor
BSY18_RS07160	COG0314	molybdopterin synthase activity
BSY18_RS07170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSY18_RS07185	COG0415	Belongs to the DNA photolyase family
BSY18_RS07215	COG0540	Belongs to the ATCase OTCase family
BSY18_RS07220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY18_RS07240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSY18_RS07240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BSY18_RS07265	COG1959	2 iron, 2 sulfur cluster binding
BSY18_RS07265	COG1295	ribonuclease BN
BSY18_RS07285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSY18_RS07290	COG2133	pyrroloquinoline quinone binding
BSY18_RS07295	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS07305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSY18_RS07310	COG0625	glutathione transferase activity
BSY18_RS07315	COG0483	inositol monophosphate 1-phosphatase activity
BSY18_RS07325	COG1074	ATP-dependent DNA helicase activity
BSY18_RS07330	COG2887	Belongs to the helicase family. UvrD subfamily
BSY18_RS07335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSY18_RS07345	COG0802	atpase or kinase
BSY18_RS07350	COG2205	protein histidine kinase activity
BSY18_RS07355	COG0793	Belongs to the peptidase S41A family
BSY18_RS07355	COG4946	Tricorn protease homolog
BSY18_RS07360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSY18_RS07365	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BSY18_RS07365	COG0678	peroxiredoxin activity
BSY18_RS07370	COG0302	gtp cyclohydrolase
BSY18_RS07375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY18_RS07410	COG2205	protein histidine kinase activity
BSY18_RS07420	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSY18_RS07440	COG0583	DNA-binding transcription factor activity
BSY18_RS07480	COG0577	efflux transmembrane transporter activity
BSY18_RS07480	COG1136	(ABC) transporter
BSY18_RS07485	COG1136	(ABC) transporter
BSY18_RS07490	COG1566	PFAM secretion protein HlyD family protein
BSY18_RS07525	COG0175	sulfate reduction
BSY18_RS07560	COG5001	Diguanylate cyclase
BSY18_RS07565	COG3507	Belongs to the glycosyl hydrolase 43 family
BSY18_RS07585	COG0477	Major facilitator Superfamily
BSY18_RS07595	COG3661	Belongs to the glycosyl hydrolase 67 family
BSY18_RS07600	COG1472	Belongs to the glycosyl hydrolase 3 family
BSY18_RS07605	COG4948	Mandelate Racemase Muconate Lactonizing
BSY18_RS07610	COG2271	Major facilitator Superfamily
BSY18_RS07625	COG4771	TonB-dependent receptor
BSY18_RS07635	COG2186	Transcriptional regulator
BSY18_RS07650	COG3258	Cytochrome c
BSY18_RS07685	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSY18_RS07695	COG3383	formate dehydrogenase (NAD+) activity
BSY18_RS07725	COG0612	Peptidase, M16
BSY18_RS07735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY18_RS07740	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY18_RS07765	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BSY18_RS07770	COG0714	Associated with various cellular activities
BSY18_RS07790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY18_RS07800	COG3447	MASE1 domain protein
BSY18_RS07800	COG5002	protein histidine kinase activity
BSY18_RS07800	COG5001	Diguanylate cyclase
BSY18_RS07810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSY18_RS07825	COG0196	riboflavin kinase activity
BSY18_RS07830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSY18_RS07835	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSY18_RS07845	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSY18_RS07855	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY18_RS07875	COG1760	l-serine dehydratase
BSY18_RS07880	COG0658	competence protein
BSY18_RS07880	COG2333	competence protein COMEC
BSY18_RS07885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY18_RS07890	COG0372	Belongs to the citrate synthase family
BSY18_RS07900	COG0406	alpha-ribazole phosphatase activity
BSY18_RS07915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSY18_RS07925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BSY18_RS07925	COG3153	acetyltransferase
BSY18_RS07930	COG0538	isocitrate dehydrogenase activity
BSY18_RS07935	COG0688	phosphatidylethanolamine metabolic process
BSY18_RS07950	COG0052	Belongs to the universal ribosomal protein uS2 family
BSY18_RS07955	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSY18_RS07960	COG0528	UMP kinase activity
BSY18_RS07965	COG0233	cytoplasmic translational termination
BSY18_RS07970	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSY18_RS07980	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSY18_RS07985	COG0750	zinc metalloprotease
BSY18_RS07990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY18_RS08000	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY18_RS08005	COG0254	rRNA binding
BSY18_RS08010	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY18_RS08015	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSY18_RS08040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY18_RS08045	COG0741	lytic transglycosylase activity
BSY18_RS08060	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS08085	COG0215	cysteine-tRNA ligase activity
BSY18_RS08110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSY18_RS08120	COG0484	heat shock protein binding
BSY18_RS08140	COG0596	Alpha beta hydrolase
BSY18_RS08155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSY18_RS08160	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BSY18_RS08165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY18_RS08170	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BSY18_RS08175	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BSY18_RS08190	COG0688	phosphatidylethanolamine metabolic process
BSY18_RS08200	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BSY18_RS08230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY18_RS08255	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BSY18_RS08275	COG1024	Enoyl-CoA hydratase
BSY18_RS08290	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS08310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY18_RS08315	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY18_RS08320	COG0509	glycine decarboxylation via glycine cleavage system
BSY18_RS08325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY18_RS08330	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSY18_RS08365	COG0514	ATP-dependent DNA helicase (RecQ)
BSY18_RS08380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY18_RS08390	COG3119	arylsulfatase activity
BSY18_RS08405	COG5001	Diguanylate cyclase
BSY18_RS08405	COG3300	MHYT domain
BSY18_RS08415	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSY18_RS08445	COG1024	Enoyl-CoA hydratase
BSY18_RS08455	COG0183	Belongs to the thiolase family
BSY18_RS08470	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS08475	COG0739	heme binding
BSY18_RS08480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY18_RS08485	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSY18_RS08500	COG2957	Belongs to the agmatine deiminase family
BSY18_RS08515	COG1573	uracil-dna glycosylase
BSY18_RS08520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BSY18_RS08560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSY18_RS08575	COG2169	Transcriptional regulator
BSY18_RS08575	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY18_RS08585	COG0840	transmembrane signaling receptor activity
BSY18_RS08590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSY18_RS08595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSY18_RS08600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSY18_RS08605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSY18_RS08610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSY18_RS08640	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BSY18_RS08650	COG1058	Belongs to the CinA family
BSY18_RS08650	COG1546	Belongs to the CinA family
BSY18_RS08665	COG0024	Methionine aminopeptidase
BSY18_RS08670	COG0347	Belongs to the P(II) protein family
BSY18_RS08675	COG0174	glutamine synthetase
BSY18_RS08690	COG4166	transmembrane transport
BSY18_RS08700	COG0583	DNA-binding transcription factor activity
BSY18_RS08710	COG2239	Acts as a magnesium transporter
BSY18_RS08720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSY18_RS08725	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY18_RS08735	COG0454	-acetyltransferase
BSY18_RS08750	COG2030	dehydratase
BSY18_RS08755	COG4770	biotin carboxylase activity
BSY18_RS08765	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY18_RS08770	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS08775	COG0583	DNA-binding transcription factor activity
BSY18_RS08785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSY18_RS08785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY18_RS08805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY18_RS08820	COG1660	Displays ATPase and GTPase activities
BSY18_RS08825	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BSY18_RS08830	COG2205	protein histidine kinase activity
BSY18_RS08835	COG0745	RESPONSE REGULATOR receiver
BSY18_RS08840	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BSY18_RS08855	COG1322	Protein conserved in bacteria
BSY18_RS08860	COG0242	peptide deformylase activity
BSY18_RS08870	COG1160	GTP binding
BSY18_RS08890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSY18_RS08895	COG0424	maF-like protein
BSY18_RS08905	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BSY18_RS08945	COG1573	uracil-dna glycosylase
BSY18_RS08960	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY18_RS08975	COG0039	L-malate dehydrogenase activity
BSY18_RS08985	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSY18_RS08990	COG2827	Endonuclease containing a URI domain
BSY18_RS09000	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY18_RS09005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY18_RS09030	COG1201	RNA secondary structure unwinding
BSY18_RS09065	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BSY18_RS09070	COG0113	porphobilinogen synthase activity
BSY18_RS09090	COG0488	(ABC) transporter
BSY18_RS09095	COG0183	Belongs to the thiolase family
BSY18_RS09130	COG1506	peptidase
BSY18_RS09130	COG4946	Tricorn protease homolog
BSY18_RS09130	COG0823	Involved in the tonB-independent uptake of proteins
BSY18_RS09140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSY18_RS09145	COG1192	Involved in chromosome partitioning
BSY18_RS09170	COG2321	neutral zinc metallopeptidase
BSY18_RS09180	COG1304	FMN binding
BSY18_RS09195	COG1459	type II secretion system
BSY18_RS09200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSY18_RS09235	COG3590	peptidase
BSY18_RS09255	COG3268	Saccharopine dehydrogenase
BSY18_RS09265	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS09275	COG0145	ligase activity
BSY18_RS09280	COG3246	L-lysine catabolic process to acetate
BSY18_RS09285	COG2814	Major facilitator Superfamily
BSY18_RS09310	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS09325	COG1376	ErfK ybiS ycfS ynhG family protein
BSY18_RS09335	COG0583	DNA-binding transcription factor activity
BSY18_RS09340	COG4221	oxidoreductase activity
BSY18_RS09350	COG0129	dihydroxy-acid dehydratase activity
BSY18_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS09385	COG1414	Transcriptional regulator
BSY18_RS09390	COG4948	Mandelate Racemase Muconate Lactonizing
BSY18_RS09395	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSY18_RS09400	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS09420	COG3693	PFAM glycoside hydrolase, family 10
BSY18_RS09465	COG0438	transferase activity, transferring glycosyl groups
BSY18_RS09495	COG1216	Glycosyl transferase, family 2
BSY18_RS09550	COG3246	L-lysine catabolic process to acetate
BSY18_RS09555	COG2175	clavaminate synthase activity
BSY18_RS09630	COG2902	Dehydrogenase
BSY18_RS09645	COG3655	Transcriptional regulator
BSY18_RS09655	COG1024	Enoyl-CoA hydratase
BSY18_RS09660	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS09665	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS09680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY18_RS09680	COG0574	Belongs to the PEP-utilizing enzyme family
BSY18_RS09685	COG0751	glycine-tRNA ligase activity
BSY18_RS09690	COG0752	glycyl-tRNA synthetase alpha subunit
BSY18_RS09695	COG0243	molybdopterin cofactor binding
BSY18_RS09720	COG0596	Alpha beta hydrolase
BSY18_RS09725	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY18_RS09730	COG3186	Phenylalanine-4-hydroxylase
BSY18_RS09735	COG1522	sequence-specific DNA binding
BSY18_RS09740	COG2860	membrane
BSY18_RS09755	COG1505	serine-type exopeptidase activity
BSY18_RS09760	COG0203	ribosomal protein L17
BSY18_RS09765	COG0202	RNA polymerase activity
BSY18_RS09770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSY18_RS09775	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSY18_RS09800	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSY18_RS09805	COG2733	membrane
BSY18_RS09835	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
BSY18_RS09850	COG2208	phosphoserine phosphatase activity
BSY18_RS09865	COG0154	amidase activity
BSY18_RS09880	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BSY18_RS09885	COG2721	sulfolactate sulfo-lyase activity
BSY18_RS09890	COG0129	dihydroxy-acid dehydratase activity
BSY18_RS09950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSY18_RS09960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY18_RS09960	COG0784	Response regulator, receiver
BSY18_RS09960	COG2205	protein histidine kinase activity
BSY18_RS09960	COG2198	Histidine kinase
BSY18_RS09990	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSY18_RS09995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY18_RS10000	COG0101	tRNA pseudouridine synthase activity
BSY18_RS10005	COG0367	asparagine synthase
BSY18_RS10030	COG3409	Peptidoglycan-binding domain 1 protein
BSY18_RS10030	COG3267	Type II secretory pathway component ExeA
BSY18_RS10060	COG2226	methyltransferase
BSY18_RS10070	COG1024	Enoyl-CoA hydratase
BSY18_RS10080	COG0625	glutathione transferase activity
BSY18_RS10085	COG0745	RESPONSE REGULATOR receiver
BSY18_RS10090	COG0436	Aminotransferase
BSY18_RS10095	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSY18_RS10115	COG4181	ATPase activity
BSY18_RS10130	COG2365	Tyrosine phosphatase family
BSY18_RS10160	COG0729	surface antigen
BSY18_RS10165	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BSY18_RS10170	COG2852	Protein conserved in bacteria
BSY18_RS10175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY18_RS10180	COG2084	Dehydrogenase
BSY18_RS10185	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BSY18_RS10200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSY18_RS10225	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY18_RS10230	COG4133	protoheme IX ABC transporter activity
BSY18_RS10235	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSY18_RS10250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSY18_RS10260	COG3138	arginine N-succinyltransferase
BSY18_RS10265	COG3724	N-succinylarginine dihydrolase activity
BSY18_RS10280	COG1970	mechanosensitive ion channel activity
BSY18_RS10290	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BSY18_RS10305	COG0189	ligase activity
BSY18_RS10310	COG0189	ligase activity
BSY18_RS10310	COG4067	protein conserved in archaea
BSY18_RS10315	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSY18_RS10325	COG0563	adenylate kinase activity
BSY18_RS10330	COG0201	protein transport
BSY18_RS10335	COG0200	Binds to the 23S rRNA
BSY18_RS10340	COG1841	ribosomal large subunit assembly
BSY18_RS10345	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSY18_RS10350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSY18_RS10355	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSY18_RS10360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSY18_RS10365	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSY18_RS10370	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSY18_RS10375	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSY18_RS10380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSY18_RS10385	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSY18_RS10390	COG0255	Belongs to the universal ribosomal protein uL29 family
BSY18_RS10395	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSY18_RS10400	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSY18_RS10405	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSY18_RS10410	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSY18_RS10415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSY18_RS10420	COG0089	rRNA binding
BSY18_RS10425	COG0088	Forms part of the polypeptide exit tunnel
BSY18_RS10430	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSY18_RS10435	COG0051	transcription antitermination factor activity, RNA binding
BSY18_RS10440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY18_RS10445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSY18_RS10450	COG0049	tRNA binding
BSY18_RS10455	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSY18_RS10465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY18_RS10470	COG0154	amidase activity
BSY18_RS10475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY18_RS10485	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSY18_RS10495	COG1643	Atp-dependent helicase
BSY18_RS10500	COG0534	Mate efflux family protein
BSY18_RS10505	COG0142	geranyltranstransferase activity
BSY18_RS10510	COG1605	Chorismate mutase
BSY18_RS10510	COG0287	Prephenate dehydrogenase
BSY18_RS10535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BSY18_RS10540	COG0488	(ABC) transporter
BSY18_RS10565	COG0667	Aldo Keto reductase
BSY18_RS10575	COG1862	Preprotein translocase
BSY18_RS10580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY18_RS10585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY18_RS10600	COG1704	LemA family
BSY18_RS10615	COG0730	response to heat
BSY18_RS10630	COG0450	alkyl hydroperoxide reductase
BSY18_RS10645	COG2391	methyltransferase activity
BSY18_RS10710	COG0523	cobalamin synthesis protein
BSY18_RS10725	COG1136	(ABC) transporter
BSY18_RS10745	COG0642	Histidine kinase
BSY18_RS10750	COG0745	RESPONSE REGULATOR receiver
BSY18_RS10760	COG1136	(ABC) transporter
BSY18_RS10785	COG0367	asparagine synthase
BSY18_RS10800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY18_RS10800	COG1017	nitric oxide dioxygenase activity
BSY18_RS10805	COG0625	glutathione transferase activity
BSY18_RS10825	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BSY18_RS10840	COG0842	Transport permease protein
BSY18_RS10850	COG0187	DNA topoisomerase II activity
BSY18_RS10870	COG2967	ApaG domain
BSY18_RS10875	COG3474	cytochrome
BSY18_RS10895	COG3046	protein related to deoxyribodipyrimidine photolyase
BSY18_RS10900	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS10905	COG3447	MASE1 domain protein
BSY18_RS10905	COG5002	protein histidine kinase activity
BSY18_RS10905	COG5001	Diguanylate cyclase
BSY18_RS10920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY18_RS10945	COG0402	S-adenosylhomocysteine deaminase activity
BSY18_RS10950	COG0531	amino acid
BSY18_RS10965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY18_RS10970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY18_RS10985	COG1301	dicarboxylic acid transport
BSY18_RS10990	COG2188	Transcriptional regulator
BSY18_RS11000	COG0779	Required for maturation of 30S ribosomal subunits
BSY18_RS11015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSY18_RS11020	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSY18_RS11035	COG1435	thymidine kinase activity
BSY18_RS11045	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSY18_RS11050	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSY18_RS11055	COG1185	polyribonucleotide nucleotidyltransferase activity
BSY18_RS11060	COG2852	Protein conserved in bacteria
BSY18_RS11070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BSY18_RS11075	COG2009	succinate dehydrogenase
BSY18_RS11100	COG4941	Belongs to the sigma-70 factor family
BSY18_RS11105	COG3795	YCII-related domain
BSY18_RS11110	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY18_RS11120	COG2853	Lipoprotein
BSY18_RS11130	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY18_RS11130	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSY18_RS11135	COG2852	Protein conserved in bacteria
BSY18_RS11140	COG1372	Participates in initiation and elongation during chromosome replication
BSY18_RS11140	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY18_RS11150	COG2205	protein histidine kinase activity
BSY18_RS11150	COG2198	Histidine kinase
BSY18_RS11150	COG0784	Response regulator, receiver
BSY18_RS11160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY18_RS11175	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSY18_RS11185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSY18_RS11190	COG0142	geranyltranstransferase activity
BSY18_RS11195	COG1722	exodeoxyribonuclease VII activity
BSY18_RS11210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY18_RS11225	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSY18_RS11230	COG0363	glucosamine-6-phosphate deaminase activity
BSY18_RS11235	COG0129	dihydroxy-acid dehydratase activity
BSY18_RS11240	COG0837	glucose binding
BSY18_RS11245	COG0800	Aldolase
BSY18_RS11255	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS11290	COG0492	ferredoxin-NADP+ reductase activity
BSY18_RS11295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSY18_RS11300	COG1755	Isoprenylcysteine carboxyl methyltransferase
BSY18_RS11310	COG0698	ribose 5-phosphate isomerase
BSY18_RS11315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSY18_RS11325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSY18_RS11345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSY18_RS11355	COG0784	Response regulator, receiver
BSY18_RS11370	COG0343	queuine tRNA-ribosyltransferase activity
BSY18_RS11380	COG0805	protein transport
BSY18_RS11385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY18_RS11390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY18_RS11395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSY18_RS11400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BSY18_RS11405	COG1472	Belongs to the glycosyl hydrolase 3 family
BSY18_RS11415	COG0018	arginyl-trna synthetase
BSY18_RS11425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSY18_RS11430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSY18_RS11435	COG0328	RNA-DNA hybrid ribonuclease activity
BSY18_RS11440	COG3422	double-strand break repair
BSY18_RS11465	COG4964	Belongs to the GSP D family
BSY18_RS11495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS11505	COG2336	PFAM SpoVT AbrB
BSY18_RS11510	COG2337	Toxic component of a toxin-antitoxin (TA) module
BSY18_RS11515	COG2066	Belongs to the glutaminase family
BSY18_RS11530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY18_RS11540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSY18_RS11545	COG0849	cell division
BSY18_RS11550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSY18_RS11555	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY18_RS11560	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSY18_RS11570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSY18_RS11575	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSY18_RS11585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSY18_RS11590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSY18_RS11595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSY18_RS11600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY18_RS11615	COG0275	rRNA processing
BSY18_RS11620	COG2001	Belongs to the MraZ family
BSY18_RS11640	COG0339	signal peptide processing
BSY18_RS11660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY18_RS11665	COG3088	subunit of a heme lyase
BSY18_RS11665	COG4235	cytochrome complex assembly
BSY18_RS11740	COG0495	leucyl-tRNA aminoacylation
BSY18_RS11755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY18_RS11775	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSY18_RS11785	COG0180	Tryptophanyl-tRNA synthetase
BSY18_RS11795	COG0756	dUTP diphosphatase activity
BSY18_RS11800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSY18_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS11835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BSY18_RS11835	COG1648	precorrin-2 dehydrogenase activity
BSY18_RS11850	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSY18_RS11860	COG0175	sulfate reduction
BSY18_RS11865	COG2200	EAL domain
BSY18_RS11875	COG1228	amidohydrolase
BSY18_RS11890	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS11910	COG1280	lysine exporter protein (LysE YggA)
BSY18_RS11920	COG2070	2-Nitropropane dioxygenase
BSY18_RS11925	COG0527	aspartate kinase activity
BSY18_RS11930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY18_RS11945	COG0305	Participates in initiation and elongation during chromosome replication
BSY18_RS11950	COG5328	Belongs to the UPF0262 family
BSY18_RS11965	COG0717	Belongs to the dCTP deaminase family
BSY18_RS11970	COG3268	Saccharopine dehydrogenase
BSY18_RS11975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSY18_RS11980	COG2234	aminopeptidase activity
BSY18_RS11985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY18_RS11990	COG3047	cAMP biosynthetic process
BSY18_RS12010	COG2010	Cytochrome c
BSY18_RS12040	COG5001	Diguanylate cyclase
BSY18_RS12045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY18_RS12050	COG1335	isochorismatase
BSY18_RS12055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS12060	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BSY18_RS12070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY18_RS12075	COG1802	Transcriptional regulator
BSY18_RS12100	COG2363	Small membrane protein
BSY18_RS12105	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BSY18_RS12120	COG2204	response regulator
BSY18_RS12130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSY18_RS12160	COG1592	Rubrerythrin
BSY18_RS12165	COG0776	regulation of translation
BSY18_RS12175	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BSY18_RS12180	COG0354	folic acid binding
BSY18_RS12200	COG0697	spore germination
BSY18_RS12225	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSY18_RS12245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSY18_RS12250	COG0072	phenylalanine-tRNA ligase activity
BSY18_RS12260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSY18_RS12265	COG0483	inositol monophosphate 1-phosphatase activity
BSY18_RS12290	COG2226	methyltransferase
BSY18_RS12300	COG1609	Transcriptional regulator
BSY18_RS12310	COG1770	oligopeptidase
BSY18_RS12315	COG3279	Response regulator of the LytR AlgR family
BSY18_RS12330	COG3713	MltA-interacting MipA family protein
BSY18_RS12355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSY18_RS12415	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY18_RS12420	COG0022	dehydrogenase e1 component
BSY18_RS12425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY18_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS12465	COG0824	Thioesterase
BSY18_RS12485	COG1983	PspC domain protein
BSY18_RS12490	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BSY18_RS12505	COG0210	DNA helicase
BSY18_RS12515	COG0525	valine-tRNA ligase activity
BSY18_RS12520	COG0823	Involved in the tonB-independent uptake of proteins
BSY18_RS12520	COG1506	peptidase
BSY18_RS12535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY18_RS12555	COG1671	Belongs to the UPF0178 family
BSY18_RS12590	COG0783	Belongs to the Dps family
BSY18_RS12630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY18_RS12635	COG3483	tryptophan 2,3-dioxygenase activity
BSY18_RS12650	COG0640	Transcriptional regulator
BSY18_RS12665	COG0646	methionine synthase
BSY18_RS12665	COG1410	methionine synthase
BSY18_RS12670	COG0475	glutathione-regulated potassium exporter activity
BSY18_RS12680	COG1253	flavin adenine dinucleotide binding
BSY18_RS12690	COG1448	Aminotransferase
BSY18_RS12750	COG2072	flavoprotein involved in K transport
BSY18_RS12755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSY18_RS12765	COG2963	transposase activity
BSY18_RS12770	COG3436	PFAM IS66 Orf2 family protein
BSY18_RS12775	COG4372	Transposase
BSY18_RS12785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY18_RS12805	COG1959	2 iron, 2 sulfur cluster binding
BSY18_RS12825	COG1017	nitric oxide dioxygenase activity
BSY18_RS12825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY18_RS12850	COG4651	solute:proton antiporter activity
BSY18_RS12850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSY18_RS12860	COG3547	Transposase (IS116 IS110 IS902 family)
BSY18_RS12865	COG2205	protein histidine kinase activity
BSY18_RS12920	COG1201	RNA secondary structure unwinding
BSY18_RS12940	COG0183	Belongs to the thiolase family
BSY18_RS12945	COG1024	Enoyl-CoA hydratase
BSY18_RS12945	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY18_RS12950	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS12960	COG2030	dehydratase
BSY18_RS12970	COG2814	Major facilitator Superfamily
BSY18_RS12980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY18_RS13005	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13010	COG2814	Major facilitator Superfamily
BSY18_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13110	COG1053	succinate dehydrogenase
BSY18_RS13125	COG2814	Major facilitator Superfamily
BSY18_RS13135	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13155	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BSY18_RS13155	COG0778	Nitroreductase
BSY18_RS13165	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
BSY18_RS13180	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS13185	COG0604	alcohol dehydrogenase
BSY18_RS13200	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13205	COG0179	Fumarylacetoacetate (FAA) hydrolase
BSY18_RS13230	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS13255	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13275	COG4993	Dehydrogenase
BSY18_RS13280	COG0300	oxidoreductase activity
BSY18_RS13305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY18_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSY18_RS13355	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS13360	COG1309	transcriptional regulator
BSY18_RS13380	COG2124	cytochrome p450
BSY18_RS13385	COG2124	cytochrome p450
BSY18_RS13410	COG1595	DNA-templated transcription, initiation
BSY18_RS13425	COG2203	Gaf domain
BSY18_RS13425	COG3706	GGDEF domain
BSY18_RS13425	COG4251	negative regulation of phosphorylation
BSY18_RS13425	COG5001	Diguanylate cyclase
BSY18_RS13455	COG1278	Cold shock
BSY18_RS13485	COG2010	Cytochrome c
BSY18_RS13485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY18_RS13490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY18_RS13500	COG0243	molybdopterin cofactor binding
BSY18_RS13505	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSY18_RS13510	COG0657	acetylesterase activity
BSY18_RS13540	COG1609	Transcriptional regulator
BSY18_RS13580	COG1392	Phosphate transport regulator
BSY18_RS13585	COG0306	phosphate transporter
BSY18_RS13595	COG4206	TonB-dependent receptor
BSY18_RS13615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY18_RS13620	COG1120	ATPase activity
BSY18_RS13625	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BSY18_RS13630	COG1492	cobalamin metabolic process
BSY18_RS13635	COG0778	Nitroreductase
BSY18_RS13640	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSY18_RS13645	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BSY18_RS13660	COG2211	Major facilitator Superfamily
BSY18_RS13670	COG1902	pentaerythritol trinitrate reductase activity
BSY18_RS13705	COG1684	flagellar biosynthetic protein fliR
BSY18_RS13710	COG1987	bacterial-type flagellum assembly
BSY18_RS13760	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BSY18_RS13770	COG1677	Flagellar hook-basal body complex protein FliE
BSY18_RS13775	COG2204	response regulator
BSY18_RS13780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BSY18_RS13785	COG1191	sigma factor activity
BSY18_RS13820	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSY18_RS13830	COG1558	bacterial-type flagellum-dependent cell motility
BSY18_RS13840	COG4786	Flagellar basal body rod
BSY18_RS13850	COG4786	Flagellar basal body rod
BSY18_RS13855	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BSY18_RS13860	COG1706	bacterial-type flagellum-dependent cell motility
BSY18_RS13880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BSY18_RS13885	COG1360	Flagellar Motor Protein
BSY18_RS13905	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS13910	COG0009	L-threonylcarbamoyladenylate synthase
BSY18_RS13915	COG0308	aminopeptidase N
BSY18_RS13925	COG0471	metal ion transport
BSY18_RS13935	COG0438	transferase activity, transferring glycosyl groups
BSY18_RS13935	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSY18_RS13940	COG1253	flavin adenine dinucleotide binding
BSY18_RS13945	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSY18_RS13950	COG1702	phosphate starvation-inducible protein PhoH
BSY18_RS13955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY18_RS13970	COG4957	zinc ion binding
BSY18_RS13985	COG0778	Nitroreductase
BSY18_RS13990	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BSY18_RS13995	COG0612	Peptidase, M16
BSY18_RS14010	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSY18_RS14015	COG0740	serine-type endopeptidase activity
BSY18_RS14020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSY18_RS14030	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSY18_RS14045	COG0596	Alpha beta hydrolase
BSY18_RS14055	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSY18_RS14060	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS14065	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSY18_RS14075	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BSY18_RS14080	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS14115	COG1999	signal sequence binding
BSY18_RS14120	COG2983	Belongs to the UPF0260 family
BSY18_RS14135	COG3609	addiction module antidote protein, CC2985 family
BSY18_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS14145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY18_RS14165	COG1131	(ABC) transporter
BSY18_RS14170	COG1329	Transcriptional regulator
BSY18_RS14175	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSY18_RS14190	COG0739	heme binding
BSY18_RS14200	COG2226	methyltransferase
BSY18_RS14220	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSY18_RS14245	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSY18_RS14250	COG0511	ligase activity, forming carbon-carbon bonds
BSY18_RS14255	COG0439	Biotin carboxylase
BSY18_RS14280	COG2258	MOSC domain
BSY18_RS14300	COG0156	8-amino-7-oxononanoate synthase activity
BSY18_RS14310	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
BSY18_RS14345	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BSY18_RS14350	COG1429	ligase activity, forming nitrogen-metal bonds
BSY18_RS14360	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY18_RS14385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY18_RS14390	COG2211	Major facilitator Superfamily
BSY18_RS14395	COG0644	oxidoreductase
BSY18_RS14435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY18_RS14445	COG2130	NADP-dependent
BSY18_RS14460	COG4771	TonB-dependent receptor
BSY18_RS14465	COG3383	formate dehydrogenase (NAD+) activity
BSY18_RS14485	COG2130	NADP-dependent
BSY18_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS14495	COG3609	addiction module antidote protein, CC2985 family
BSY18_RS14505	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS14515	COG0183	Belongs to the thiolase family
BSY18_RS14530	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS14550	COG4638	Rieske (2fe-2S)
BSY18_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS14615	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY18_RS14620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSY18_RS14630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY18_RS14630	COG3743	rRNA binding
BSY18_RS14635	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSY18_RS14640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSY18_RS14675	COG1968	undecaprenyl-diphosphatase activity
BSY18_RS14680	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BSY18_RS14690	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSY18_RS14695	COG0706	membrane insertase activity
BSY18_RS14700	COG0594	ribonuclease P activity
BSY18_RS14715	COG0312	modulator of DNA gyrase
BSY18_RS14720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY18_RS14720	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BSY18_RS14740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
BSY18_RS14765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY18_RS14780	COG5265	(ABC) transporter
BSY18_RS14795	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BSY18_RS14800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY18_RS14800	COG2813	Specifically methylates the guanine in position
BSY18_RS14805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY18_RS14820	COG0408	coproporphyrinogen oxidase activity
BSY18_RS14825	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSY18_RS14880	COG1116	anion transmembrane transporter activity
BSY18_RS14885	COG0864	Transcriptional regulator
BSY18_RS14925	COG0457	Tetratricopeptide repeat
BSY18_RS14950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY18_RS14955	COG0463	Glycosyl transferase, family 2
BSY18_RS14965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY18_RS14980	COG4957	zinc ion binding
BSY18_RS14985	COG0586	Pfam SNARE associated Golgi protein
BSY18_RS14990	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS15005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY18_RS15005	COG0546	phosphoglycolate phosphatase activity
BSY18_RS15015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BSY18_RS15030	COG4957	zinc ion binding
BSY18_RS15035	COG0586	Pfam SNARE associated Golgi protein
BSY18_RS15040	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS15045	COG0277	FAD linked oxidase domain protein
BSY18_RS15055	COG0546	phosphoglycolate phosphatase activity
BSY18_RS15055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY18_RS15060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSY18_RS15065	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS15075	COG0312	modulator of DNA gyrase
BSY18_RS15085	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSY18_RS15090	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSY18_RS15095	COG0583	DNA-binding transcription factor activity
BSY18_RS15105	COG0281	malic enzyme
BSY18_RS15105	COG0280	phosphate acetyltransferase
BSY18_RS15110	COG1024	Enoyl-CoA hydratase
BSY18_RS15130	COG1238	metal cluster binding
BSY18_RS15175	COG1937	Protein conserved in bacteria
BSY18_RS15200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BSY18_RS15260	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BSY18_RS15270	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSY18_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS15310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY18_RS15315	COG5001	Diguanylate cyclase
BSY18_RS15355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS15375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSY18_RS15385	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS15390	COG0277	FAD linked oxidase domain protein
BSY18_RS15400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS15405	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS15410	COG1414	Transcriptional regulator
BSY18_RS15455	COG4771	TonB-dependent receptor
BSY18_RS15460	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BSY18_RS15465	COG0066	3-isopropylmalate dehydratase activity
BSY18_RS15470	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY18_RS15505	COG3949	Membrane
BSY18_RS15515	COG4774	siderophore transport
BSY18_RS15520	COG4948	Mandelate Racemase Muconate Lactonizing
BSY18_RS15525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSY18_RS15535	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BSY18_RS15545	COG0248	Ppx GppA phosphatase
BSY18_RS15550	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSY18_RS15570	COG1054	Belongs to the UPF0176 family
BSY18_RS15585	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BSY18_RS15590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BSY18_RS15610	COG3387	PFAM Glycoside hydrolase 15-related
BSY18_RS15615	COG1877	trehalose-phosphatase activity
BSY18_RS15650	COG2884	Cell division ATP-binding protein ftsE
BSY18_RS15680	COG0357	Ribosomal RNA small subunit methyltransferase G
BSY18_RS15685	COG0445	tRNA wobble uridine modification
BSY18_RS15690	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSY18_RS15725	COG0861	Integral membrane protein TerC family
BSY18_RS15730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSY18_RS15740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSY18_RS15745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSY18_RS15750	COG0424	maF-like protein
BSY18_RS15755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY18_RS15760	COG0237	dephospho-CoA kinase activity
BSY18_RS15765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSY18_RS15770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSY18_RS15805	COG2022	thiamine diphosphate biosynthetic process
BSY18_RS15815	COG1612	heme a metabolic process
BSY18_RS15820	COG1324	tolerance protein
BSY18_RS15830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSY18_RS15835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSY18_RS15845	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY18_RS15850	COG0250	Participates in transcription elongation, termination and antitermination
BSY18_RS15855	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSY18_RS15860	COG0081	regulation of translation
BSY18_RS15875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSY18_RS15880	COG0222	ribosome binding
BSY18_RS15885	COG2171	N-acyltransferase activity
BSY18_RS15895	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSY18_RS15900	COG4152	abc transporter atp-binding protein
BSY18_RS15910	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS15925	COG0330	HflC and HflK could
BSY18_RS15930	COG0489	protein tyrosine kinase activity
BSY18_RS15940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSY18_RS15945	COG0433	COG0433 Predicted ATPase
BSY18_RS15950	COG0517	IMP dehydrogenase activity
BSY18_RS15960	COG1607	acyl-coa hydrolase
BSY18_RS15970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSY18_RS15975	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSY18_RS15980	COG0181	hydroxymethylbilane synthase activity
BSY18_RS15995	COG0746	molybdenum cofactor guanylyltransferase activity
BSY18_RS16015	COG1482	cell wall glycoprotein biosynthetic process
BSY18_RS16025	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY18_RS16045	COG3335	DDE superfamily endonuclease
BSY18_RS16055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY18_RS16065	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSY18_RS16080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSY18_RS16120	COG0489	protein tyrosine kinase activity
BSY18_RS16130	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BSY18_RS16130	COG2755	lipolytic protein G-D-S-L family
BSY18_RS16150	COG1216	Glycosyl transferase, family 2
BSY18_RS16200	COG1024	Enoyl-CoA hydratase
BSY18_RS16220	COG0154	amidase activity
BSY18_RS16225	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BSY18_RS16240	COG2188	Transcriptional regulator
BSY18_RS16250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS16260	COG2030	dehydratase
BSY18_RS16265	COG2301	Belongs to the HpcH HpaI aldolase family
BSY18_RS16355	COG1335	isochorismatase
BSY18_RS16370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY18_RS16385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS16395	COG0753	catalase activity
BSY18_RS16405	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSY18_RS16455	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY18_RS16485	COG0438	transferase activity, transferring glycosyl groups
BSY18_RS16500	COG1063	alcohol dehydrogenase
BSY18_RS16525	COG3275	phosphorelay sensor kinase activity
BSY18_RS16530	COG0405	Gamma-glutamyltransferase
BSY18_RS16540	COG0167	dihydroorotate dehydrogenase activity
BSY18_RS16570	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BSY18_RS16575	COG2885	chlorophyll binding
BSY18_RS16580	COG1253	flavin adenine dinucleotide binding
BSY18_RS16605	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSY18_RS16610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSY18_RS16635	COG0670	Belongs to the BI1 family
BSY18_RS16665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSY18_RS16695	COG2095	MarC family integral membrane protein
BSY18_RS16705	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSY18_RS16715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSY18_RS16735	COG0347	Belongs to the P(II) protein family
BSY18_RS16740	COG0004	ammonium transporteR
BSY18_RS16750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY18_RS16755	COG0513	Belongs to the DEAD box helicase family
BSY18_RS16800	COG1959	2 iron, 2 sulfur cluster binding
BSY18_RS16805	COG0719	Fe-S assembly protein
BSY18_RS16815	COG0396	ATPase activity
BSY18_RS16825	COG0719	Fe-S assembly protein
BSY18_RS16830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BSY18_RS16835	COG2151	metal-sulfur cluster biosynthetic enzyme
BSY18_RS16840	COG0316	Belongs to the HesB IscA family
BSY18_RS16855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY18_RS16855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY18_RS16880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY18_RS16885	COG0287	Prephenate dehydrogenase
BSY18_RS16900	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSY18_RS16905	COG1127	ABC transporter
BSY18_RS16920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSY18_RS16940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BSY18_RS16975	COG4191	Histidine kinase
BSY18_RS16975	COG0784	Response regulator, receiver
BSY18_RS16990	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS17015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS17020	COG1414	Transcriptional regulator
BSY18_RS17025	COG4774	siderophore transport
BSY18_RS17030	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSY18_RS17050	COG0784	Response regulator, receiver
BSY18_RS17050	COG4191	Histidine kinase
BSY18_RS17065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY18_RS17075	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSY18_RS17090	COG2824	Alkylphosphonate utilization operon protein PhnA
BSY18_RS17110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BSY18_RS17115	COG1794	racemase activity, acting on amino acids and derivatives
BSY18_RS17120	COG0501	Belongs to the peptidase M48B family
BSY18_RS17125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY18_RS17145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY18_RS17150	COG0268	Binds directly to 16S ribosomal RNA
BSY18_RS17155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSY18_RS17160	COG2226	methyltransferase
BSY18_RS17165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY18_RS17170	COG0640	Transcriptional regulator
BSY18_RS17175	COG1902	pentaerythritol trinitrate reductase activity
BSY18_RS17195	COG0085	RNA polymerase activity
BSY18_RS17200	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSY18_RS17215	COG0655	NAD(P)H dehydrogenase (quinone) activity
BSY18_RS17235	COG0477	Major facilitator Superfamily
BSY18_RS17245	COG0742	ribosomal rna small subunit methyltransferase
BSY18_RS17250	COG1187	pseudouridine synthase activity
BSY18_RS17265	COG2271	Major facilitator Superfamily
BSY18_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS17295	COG2272	Belongs to the type-B carboxylesterase lipase family
BSY18_RS17310	COG4771	TonB-dependent receptor
BSY18_RS17320	COG3507	Belongs to the glycosyl hydrolase 43 family
BSY18_RS17325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BSY18_RS17335	COG0284	orotidine-5'-phosphate decarboxylase activity
BSY18_RS17340	COG0135	phosphoribosylanthranilate isomerase activity
BSY18_RS17345	COG0133	tryptophan synthase activity
BSY18_RS17350	COG0159	tryptophan synthase activity
BSY18_RS17355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSY18_RS17360	COG0285	dihydrofolate synthase activity
BSY18_RS17365	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS17370	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS17375	COG0492	ferredoxin-NADP+ reductase activity
BSY18_RS17380	COG1024	Enoyl-CoA hydratase
BSY18_RS17420	COG1215	transferase activity, transferring glycosyl groups
BSY18_RS17430	COG0730	response to heat
BSY18_RS17445	COG0602	queuosine metabolic process
BSY18_RS17475	COG4695	Portal protein
BSY18_RS17575	COG5487	UPF0391 membrane protein
BSY18_RS17580	COG0628	permease
BSY18_RS17585	COG1674	ftsk spoiiie
BSY18_RS17590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS17595	COG1309	transcriptional regulator
BSY18_RS17600	COG4774	siderophore transport
BSY18_RS17610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY18_RS17615	COG0601	transmembrane transport
BSY18_RS17625	COG0789	Transcriptional regulator
BSY18_RS17640	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BSY18_RS17640	COG1918	ferrous iron import across plasma membrane
BSY18_RS17645	COG0629	single-stranded DNA binding
BSY18_RS17655	COG4689	acetoacetate decarboxylase
BSY18_RS17670	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS17690	COG2925	Exonuclease
BSY18_RS17730	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY18_RS17770	COG1733	regulation of RNA biosynthetic process
BSY18_RS17785	COG5507	3-demethylubiquinone-9 3-methyltransferase
BSY18_RS17810	COG0625	glutathione transferase activity
BSY18_RS17815	COG1940	carbohydrate kinase activity
BSY18_RS17820	COG1621	beta-fructofuranosidase activity
BSY18_RS17835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSY18_RS17865	COG1278	Cold shock
BSY18_RS17870	COG1253	flavin adenine dinucleotide binding
BSY18_RS17890	COG1137	ATPase activity
BSY18_RS17895	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSY18_RS17925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSY18_RS17945	COG0583	DNA-binding transcription factor activity
BSY18_RS17950	COG0686	Belongs to the AlaDH PNT family
BSY18_RS17975	COG4774	siderophore transport
BSY18_RS17990	COG1131	(ABC) transporter
BSY18_RS18005	COG3631	Ketosteroid isomerase-related protein
BSY18_RS18010	COG0702	epimerase
BSY18_RS18025	COG0583	DNA-binding transcription factor activity
BSY18_RS18045	COG0024	Methionine aminopeptidase
BSY18_RS18075	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY18_RS18085	COG2207	Transcriptional regulator
BSY18_RS18090	COG4221	oxidoreductase activity
BSY18_RS18095	COG0667	Aldo Keto reductase
BSY18_RS18115	COG2814	Major facilitator Superfamily
BSY18_RS18125	COG1024	Enoyl-CoA hydratase
BSY18_RS18160	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BSY18_RS18185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS18200	COG2936	dipeptidyl-peptidase activity
BSY18_RS18235	COG2271	Major facilitator Superfamily
BSY18_RS18255	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY18_RS18260	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BSY18_RS18270	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS18305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BSY18_RS18340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS18350	COG4771	TonB-dependent receptor
BSY18_RS18360	COG3618	amidohydrolase
BSY18_RS18370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSY18_RS18385	COG2159	amidohydrolase
BSY18_RS18405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY18_RS18415	COG0745	RESPONSE REGULATOR receiver
BSY18_RS18435	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSY18_RS18455	COG1064	alcohol dehydrogenase
BSY18_RS18470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS18475	COG2271	Major facilitator Superfamily
BSY18_RS18485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY18_RS18490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSY18_RS18495	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY18_RS18515	COG4452	Inner membrane protein CreD
BSY18_RS18530	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BSY18_RS18535	COG0596	Alpha beta hydrolase
BSY18_RS18535	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY18_RS18540	COG0500	methyltransferase
BSY18_RS18545	COG1063	alcohol dehydrogenase
BSY18_RS18550	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BSY18_RS18555	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY18_RS18560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BSY18_RS18600	COG1473	amidohydrolase
BSY18_RS18620	COG0556	nucleotide-excision repair
BSY18_RS18635	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSY18_RS18695	COG2816	NAD+ diphosphatase activity
BSY18_RS18715	COG1024	Enoyl-CoA hydratase
BSY18_RS18720	COG0667	Aldo Keto reductase
BSY18_RS18725	COG4638	Rieske (2fe-2S)
BSY18_RS18730	COG5285	phytanoyl-CoA dioxygenase
BSY18_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS18750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY18_RS18755	COG0183	Belongs to the thiolase family
BSY18_RS18765	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BSY18_RS18785	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS18790	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS18800	COG1024	Enoyl-CoA hydratase
BSY18_RS18815	COG1053	succinate dehydrogenase
BSY18_RS18820	COG2186	Transcriptional regulator
BSY18_RS18825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BSY18_RS18830	COG0022	dehydrogenase e1 component
BSY18_RS18850	COG1773	rubredoxin
BSY18_RS18855	COG2124	cytochrome p450
BSY18_RS18860	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BSY18_RS18870	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS18875	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS18885	COG0477	Major facilitator Superfamily
BSY18_RS18890	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS18895	COG1960	acyl-CoA dehydrogenase activity
BSY18_RS18900	COG1024	Enoyl-CoA hydratase
BSY18_RS18905	COG2814	Major facilitator Superfamily
BSY18_RS18910	COG4774	siderophore transport
BSY18_RS18920	COG1024	Enoyl-CoA hydratase
BSY18_RS18925	COG1902	pentaerythritol trinitrate reductase activity
BSY18_RS18930	COG0667	Aldo Keto reductase
BSY18_RS18935	COG2050	protein possibly involved in aromatic compounds catabolism
BSY18_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS18985	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BSY18_RS18990	COG1606	tRNA processing
BSY18_RS18995	COG1691	(AIR) carboxylase
BSY18_RS19000	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
BSY18_RS19010	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS19040	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS19045	COG0318	PFAM AMP-dependent synthetase and ligase
BSY18_RS19070	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS19085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY18_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
BSY18_RS19105	COG1012	belongs to the aldehyde dehydrogenase family
BSY18_RS19125	COG1082	Xylose isomerase domain protein TIM barrel
BSY18_RS19130	COG0366	Alpha amylase catalytic
BSY18_RS19165	COG3002	Belongs to the UPF0753 family
BSY18_RS19170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY18_RS19200	COG2855	membrane
BSY18_RS19205	COG2271	Major facilitator Superfamily
BSY18_RS19220	COG4771	TonB-dependent receptor
BSY18_RS19225	COG1501	Belongs to the glycosyl hydrolase 31 family
BSY18_RS19235	COG0667	Aldo Keto reductase
BSY18_RS19240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY18_RS19250	COG0431	NADPH-dependent FMN reductase
BSY18_RS19255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY18_RS19255	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BSY18_RS19260	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSY18_RS19265	COG0415	Belongs to the DNA photolyase family
BSY18_RS19295	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSY18_RS19310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BSY18_RS19315	COG0539	negative regulation of cytoplasmic translation
BSY18_RS19330	COG2199	diguanylate cyclase activity
BSY18_RS19345	COG4106	trans-aconitate 2-methyltransferase activity
BSY18_RS19380	COG2264	protein methyltransferase activity
BSY18_RS19390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY18_RS19400	COG2096	Adenosyltransferase
BSY18_RS19405	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY18_RS19410	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BSY18_RS19415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY18_RS19420	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSY18_RS19435	COG1192	Involved in chromosome partitioning
BSY18_RS19670	COG3156	type II secretion system protein K
BSY18_RS19785	COG0573	inorganic phosphate transmembrane transporter activity
BSY18_RS19855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BSY18_RS20060	COG2205	protein histidine kinase activity
BSY18_RS20310	COG4774	siderophore transport
BSY18_RS20330	COG1904	glucuronate isomerase
BSY18_RS20370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family