locus-tag	class	description
STAT_RS00005	COG2251	uridine kinase activity
STAT_RS00005	COG0195	Participates in both transcription termination and antitermination
STAT_RS00010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
STAT_RS00015	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
STAT_RS00025	COG0508	dehydrogenase complex catalyzes the overall conversion of
STAT_RS00030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
STAT_RS00030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
STAT_RS00035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
STAT_RS00045	COG0772	Belongs to the SEDS family
STAT_RS00050	COG0768	penicillin binding
STAT_RS00060	COG1792	Involved in formation and maintenance of cell shape
STAT_RS00065	COG1077	Cell shape determining protein MreB Mrl
STAT_RS00080	COG0251	oxidation-reduction process
STAT_RS00090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STAT_RS00095	COG0101	tRNA pseudouridine synthase activity
STAT_RS00100	COG1132	(ABC) transporter
STAT_RS00120	COG0039	L-malate dehydrogenase activity
STAT_RS00125	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STAT_RS00125	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
STAT_RS00130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
STAT_RS00140	COG1522	sequence-specific DNA binding
STAT_RS00175	COG1210	Utp--glucose-1-phosphate uridylyltransferase
STAT_RS00180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STAT_RS00190	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
STAT_RS00195	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
STAT_RS00195	COG0321	lipoyl(octanoyl) transferase activity
STAT_RS00200	COG1333	cytochrome c biogenesis protein
STAT_RS00200	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
STAT_RS00210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
STAT_RS00220	COG0508	dehydrogenase complex catalyzes the overall conversion of
STAT_RS00235	COG1136	(ABC) transporter
STAT_RS00240	COG0045	succinate-CoA ligase (ADP-forming) activity
STAT_RS00245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
STAT_RS00250	COG0542	response to heat
STAT_RS00255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
STAT_RS00270	COG2151	metal-sulfur cluster biosynthetic enzyme
STAT_RS00280	COG0612	Peptidase, M16
STAT_RS00290	COG0437	4 iron, 4 sulfur cluster binding
STAT_RS00320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
STAT_RS00330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
STAT_RS00335	COG0302	gtp cyclohydrolase
STAT_RS00340	COG0215	cysteine-tRNA ligase activity
STAT_RS00345	COG0626	cystathionine gamma-synthase activity
STAT_RS00350	COG0356	it plays a direct role in the translocation of protons across the membrane
STAT_RS00355	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STAT_RS00360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
STAT_RS00365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
STAT_RS00375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
STAT_RS00380	COG0180	Tryptophanyl-tRNA synthetase
STAT_RS00385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
STAT_RS00390	COG0484	heat shock protein binding
STAT_RS00395	COG0482	sulfurtransferase activity
STAT_RS00405	COG0028	Belongs to the TPP enzyme family
STAT_RS00415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
STAT_RS00420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
STAT_RS00430	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
STAT_RS00435	COG0681	Belongs to the peptidase S26 family
STAT_RS00445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
STAT_RS00450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
STAT_RS00470	COG0776	regulation of translation
STAT_RS00475	COG1530	ribonuclease E activity
STAT_RS00500	COG0084	hydrolase, TatD family'
STAT_RS00515	COG0445	tRNA wobble uridine modification
STAT_RS00525	COG1183	phosphatidylcholine synthase activity
STAT_RS00535	COG0326	Molecular chaperone. Has ATPase activity
STAT_RS00540	COG0552	protein localization to endoplasmic reticulum
STAT_RS00550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
STAT_RS00555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
STAT_RS00560	COG0217	transcriptional regulatory protein
STAT_RS00595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
STAT_RS00600	COG0439	Biotin carboxylase
STAT_RS00605	COG0511	ligase activity, forming carbon-carbon bonds
STAT_RS00610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
STAT_RS00620	COG0167	dihydroorotate dehydrogenase activity
STAT_RS00625	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
STAT_RS00630	COG2095	MarC family integral membrane protein
STAT_RS00640	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
STAT_RS00650	COG0756	dUTP diphosphatase activity
STAT_RS00675	COG0328	RNA-DNA hybrid ribonuclease activity
STAT_RS00680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STAT_RS00705	COG0460	homoserine dehydrogenase
STAT_RS00705	COG0527	aspartate kinase activity
STAT_RS00710	COG0083	homoserine kinase activity
STAT_RS00715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
STAT_RS00720	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
STAT_RS00725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
STAT_RS00730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
STAT_RS00750	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
STAT_RS00760	COG0793	Belongs to the peptidase S41A family
STAT_RS00765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
STAT_RS00770	COG2255	four-way junction helicase activity
STAT_RS00775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
STAT_RS00780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
STAT_RS00785	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
STAT_RS00790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
STAT_RS00795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
STAT_RS00800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
STAT_RS00810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
STAT_RS00815	COG0138	bifunctional purine biosynthesis protein purh
STAT_RS00820	COG0151	Belongs to the GarS family
STAT_RS00825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
STAT_RS00825	COG0519	Catalyzes the synthesis of GMP from XMP
STAT_RS00830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
STAT_RS00835	COG0191	fructose-bisphosphate aldolase activity
STAT_RS00840	COG1074	ATP-dependent DNA helicase activity
STAT_RS00845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
STAT_RS00850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
STAT_RS00865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STAT_RS00870	COG0517	IMP dehydrogenase activity
STAT_RS00870	COG0617	tRNA 3'-terminal CCA addition
STAT_RS00870	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
STAT_RS00880	COG2171	N-acyltransferase activity
STAT_RS00885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
STAT_RS00895	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
STAT_RS00900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
STAT_RS00905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
STAT_RS00910	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
STAT_RS00915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
STAT_RS00925	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
STAT_RS00930	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
STAT_RS00935	COG0018	arginyl-trna synthetase
STAT_RS00940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
STAT_RS00950	COG0105	UTP biosynthetic process
STAT_RS00955	COG1704	LemA family
STAT_RS00965	COG0525	valine-tRNA ligase activity
STAT_RS00985	COG0022	dehydrogenase e1 component
STAT_RS00985	COG0508	dehydrogenase complex catalyzes the overall conversion of
STAT_RS00990	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
STAT_RS00995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
STAT_RS01000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
STAT_RS01005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
STAT_RS01010	COG0602	queuosine metabolic process
STAT_RS01015	COG0140	phosphoribosyl-ATP diphosphatase activity
STAT_RS01015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
STAT_RS01020	COG0107	imidazoleglycerol-phosphate synthase activity
STAT_RS01025	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
STAT_RS01030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
STAT_RS01035	COG0131	Imidazoleglycerol-phosphate dehydratase
STAT_RS01040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
STAT_RS01045	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
STAT_RS01050	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
STAT_RS01055	COG0708	Exodeoxyribonuclease III
STAT_RS01065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
STAT_RS01075	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
STAT_RS01080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
STAT_RS01090	COG0133	tryptophan synthase activity
STAT_RS01095	COG0135	phosphoribosylanthranilate isomerase activity
STAT_RS01100	COG0134	indole-3-glycerol-phosphate synthase activity
STAT_RS01105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
STAT_RS01110	COG0512	Glutamine amidotransferase of anthranilate synthase
STAT_RS01110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
STAT_RS01115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
STAT_RS01130	COG0509	glycine decarboxylation via glycine cleavage system
STAT_RS01135	COG2217	Heavy metal translocating P-type atpase
STAT_RS01170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
STAT_RS01175	COG0268	Binds directly to 16S ribosomal RNA
STAT_RS01200	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
STAT_RS01205	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
STAT_RS01210	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
STAT_RS01215	COG2885	chlorophyll binding
STAT_RS01220	COG0805	protein transport
STAT_RS01225	COG0012	GTP binding
STAT_RS01230	COG1363	Peptidase, m42
STAT_RS01235	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
STAT_RS01240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
STAT_RS01250	COG0343	queuine tRNA-ribosyltransferase activity
STAT_RS01265	COG0768	penicillin binding
STAT_RS01270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
STAT_RS01275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
STAT_RS01285	COG0772	Belongs to the SEDS family
STAT_RS01290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
STAT_RS01295	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
STAT_RS01310	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
STAT_RS01315	COG0124	histidyl-tRNA synthetase
STAT_RS01330	COG0489	protein tyrosine kinase activity
STAT_RS01335	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
STAT_RS01340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
STAT_RS01355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
STAT_RS01385	COG0632	four-way junction helicase activity
STAT_RS01390	COG1160	GTP binding
STAT_RS01395	COG0336	Belongs to the RNA methyltransferase TrmD family
STAT_RS01400	COG0165	Argininosuccinate lyase
STAT_RS01405	COG0187	DNA topoisomerase II activity
STAT_RS01410	COG1968	undecaprenyl-diphosphatase activity
STAT_RS01415	COG0228	four-way junction DNA binding
STAT_RS01425	COG1301	dicarboxylic acid transport
STAT_RS01440	COG0436	Aminotransferase
STAT_RS01445	COG0357	Ribosomal RNA small subunit methyltransferase G
STAT_RS01450	COG0402	S-adenosylhomocysteine deaminase activity
STAT_RS01455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
STAT_RS01460	COG0321	lipoyl(octanoyl) transferase activity
STAT_RS01465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
STAT_RS01470	COG0450	alkyl hydroperoxide reductase
STAT_RS01475	COG0358	DNA primase activity
STAT_RS01480	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
STAT_RS01485	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
STAT_RS01490	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
STAT_RS01495	COG1605	Chorismate mutase
STAT_RS01495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
STAT_RS01500	COG0287	Prephenate dehydrogenase
STAT_RS01505	COG0436	Aminotransferase
STAT_RS01510	COG1605	Chorismate mutase
STAT_RS01510	COG0077	Prephenate dehydratase
STAT_RS01515	COG1914	H( )-stimulated, divalent metal cation uptake system
STAT_RS01520	COG0359	binds to the 23S rRNA
STAT_RS01530	COG0360	Binds together with S18 to 16S ribosomal RNA
STAT_RS01535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
STAT_RS01540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
STAT_RS01545	COG2890	protein-(glutamine-N5) methyltransferase activity
STAT_RS01550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
STAT_RS01560	COG0019	diaminopimelate decarboxylase activity
STAT_RS01570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STAT_RS01570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
STAT_RS01575	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STAT_RS01575	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
STAT_RS01590	COG1674	ftsk spoiiie
STAT_RS01600	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STAT_RS01600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
STAT_RS01610	COG3118	belongs to the thioredoxin family
STAT_RS01615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
STAT_RS01620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
STAT_RS01625	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
STAT_RS01635	COG0505	Belongs to the CarA family
STAT_RS01640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
STAT_RS01650	COG0137	argininosuccinate synthase activity
STAT_RS01660	COG0539	negative regulation of cytoplasmic translation
STAT_RS01665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
STAT_RS01695	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
STAT_RS01715	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
STAT_RS01720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
STAT_RS01725	COG0194	GDP metabolic process
STAT_RS01735	COG0698	ribose 5-phosphate isomerase
STAT_RS01740	COG0126	phosphoglycerate kinase activity
STAT_RS01745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
STAT_RS01765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
STAT_RS01770	COG0297	glycogen (starch) synthase activity
STAT_RS01775	COG0557	exoribonuclease II activity
STAT_RS01780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
STAT_RS01785	COG1774	PSP1 C-terminal conserved region
STAT_RS01795	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
STAT_RS01800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
STAT_RS01810	COG1045	serine acetyltransferase
STAT_RS01815	COG0538	isocitrate dehydrogenase activity
STAT_RS01830	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
STAT_RS01835	COG1575	Belongs to the MenA family. Type 1 subfamily
STAT_RS01840	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
STAT_RS01855	COG0148	phosphopyruvate hydratase activity
STAT_RS01860	COG0203	ribosomal protein L17
STAT_RS01865	COG0202	RNA polymerase activity
STAT_RS01870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
STAT_RS01880	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
STAT_RS01885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
STAT_RS01890	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
STAT_RS01895	COG0201	protein transport
STAT_RS01900	COG0200	Binds to the 23S rRNA
STAT_RS01910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
STAT_RS01915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
STAT_RS01920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
STAT_RS01930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
STAT_RS01935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
STAT_RS01950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
STAT_RS01955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
STAT_RS01960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
STAT_RS01965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
STAT_RS01970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
STAT_RS01980	COG0088	Forms part of the polypeptide exit tunnel
STAT_RS01990	COG0051	transcription antitermination factor activity, RNA binding
STAT_RS02015	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
STAT_RS02020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
STAT_RS02025	COG0052	Belongs to the universal ribosomal protein uS2 family
STAT_RS02030	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
STAT_RS02035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
STAT_RS02045	COG0688	phosphatidylethanolamine metabolic process
STAT_RS02050	COG4589	Belongs to the CDS family
STAT_RS02055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
STAT_RS02060	COG0799	negative regulation of ribosome biogenesis
STAT_RS02065	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
STAT_RS02065	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
STAT_RS02070	COG0706	membrane insertase activity
STAT_RS02075	COG0504	CTP synthase activity
STAT_RS02080	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
STAT_RS02090	COG0563	adenylate kinase activity
STAT_RS02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STAT_RS02100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
STAT_RS02110	COG1528	Iron-storage protein
STAT_RS02120	COG0724	RNA recognition motif
STAT_RS02125	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
STAT_RS02150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
STAT_RS02170	COG1132	(ABC) transporter
STAT_RS02175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
STAT_RS02180	COG1862	Preprotein translocase
STAT_RS02200	COG1252	NADH dehydrogenase
STAT_RS02210	COG2050	protein possibly involved in aromatic compounds catabolism
STAT_RS02215	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
STAT_RS02225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
STAT_RS02255	COG0285	dihydrofolate synthase activity
STAT_RS02260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
STAT_RS02265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
STAT_RS02270	COG0085	RNA polymerase activity
STAT_RS02275	COG0222	ribosome binding
STAT_RS02280	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
STAT_RS02285	COG0081	regulation of translation
STAT_RS02335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
STAT_RS02340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
STAT_RS02345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
STAT_RS02350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
STAT_RS02365	COG0517	IMP dehydrogenase activity
STAT_RS02365	COG0516	GMP reductase activity
STAT_RS02375	COG0335	large ribosomal subunit rRNA binding
STAT_RS02380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
STAT_RS02395	COG0825	malonyl-CoA metabolic process
STAT_RS02400	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
STAT_RS02405	COG1053	succinate dehydrogenase
STAT_RS02415	COG1104	cysteine desulfurase activity
STAT_RS02420	COG1418	mRNA catabolic process
STAT_RS02430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
STAT_RS02435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
STAT_RS02440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
STAT_RS02450	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STAT_RS02450	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
STAT_RS02455	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
STAT_RS02470	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
STAT_RS02475	COG0210	DNA helicase
STAT_RS02490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
STAT_RS02495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
STAT_RS02505	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
STAT_RS02510	COG0596	Alpha beta hydrolase
STAT_RS02515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
STAT_RS02520	COG0750	zinc metalloprotease
STAT_RS02535	COG1181	Belongs to the D-alanine--D-alanine ligase family
STAT_RS02545	COG0564	pseudouridine synthase activity
STAT_RS02550	COG2239	Acts as a magnesium transporter
STAT_RS02555	COG0495	leucyl-tRNA aminoacylation
STAT_RS02560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
STAT_RS02565	COG0528	UMP kinase activity
STAT_RS02570	COG0233	cytoplasmic translational termination
STAT_RS02575	COG0017	Asparaginyl-tRNA synthetase
STAT_RS02580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
STAT_RS02585	COG1012	belongs to the aldehyde dehydrogenase family
STAT_RS02590	COG2166	iron-sulfur cluster assembly
STAT_RS02595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
STAT_RS02600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
STAT_RS02605	COG0254	rRNA binding
STAT_RS02610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
STAT_RS02615	COG2226	methyltransferase
STAT_RS02625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
STAT_RS02635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
STAT_RS02645	COG0149	triose-phosphate isomerase activity
STAT_RS02655	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
STAT_RS02665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
STAT_RS02670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
STAT_RS02675	COG0508	dehydrogenase complex catalyzes the overall conversion of
STAT_RS02680	COG0861	Integral membrane protein TerC family
STAT_RS02685	COG1132	(ABC) transporter
STAT_RS02690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
STAT_RS02690	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
STAT_RS02695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
STAT_RS02705	COG1253	flavin adenine dinucleotide binding
STAT_RS02725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
STAT_RS02730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
STAT_RS02735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
STAT_RS02745	COG1187	pseudouridine synthase activity
STAT_RS02750	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
STAT_RS02760	COG0571	ribonuclease III activity
STAT_RS02765	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
STAT_RS02770	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
STAT_RS02775	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
STAT_RS02780	COG0307	riboflavin synthase, alpha
STAT_RS02785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
STAT_RS02790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
STAT_RS02800	COG0196	riboflavin kinase activity
STAT_RS02815	COG0066	3-isopropylmalate dehydratase activity
STAT_RS02820	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
STAT_RS02825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
STAT_RS02840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
STAT_RS02850	COG0542	response to heat
STAT_RS02855	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
STAT_RS02860	COG1166	arginine decarboxylase activity
STAT_RS02865	COG0010	Belongs to the arginase family
STAT_RS02870	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
STAT_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
STAT_RS02880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
STAT_RS02885	COG2949	membrane
STAT_RS02890	COG0653	protein targeting
STAT_RS02900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
STAT_RS02910	COG0259	pyridoxamine-phosphate oxidase activity
STAT_RS02920	COG0592	DNA-directed DNA polymerase activity
STAT_RS02930	COG0423	glycine-tRNA ligase activity
STAT_RS02935	COG0492	ferredoxin-NADP+ reductase activity
STAT_RS02945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
STAT_RS02950	COG0481	GTPase activity
STAT_RS02960	COG0193	aminoacyl-tRNA hydrolase activity
STAT_RS02965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
STAT_RS02980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
STAT_RS03000	COG4591	ABC-type transport system involved in lipoprotein release permease component
STAT_RS03020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
STAT_RS03025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
STAT_RS03030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
STAT_RS03035	COG0719	Fe-S assembly protein
STAT_RS03040	COG0396	ATPase activity
STAT_RS03045	COG0719	Fe-S assembly protein
STAT_RS03050	COG0316	Belongs to the HesB IscA family
STAT_RS03060	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
STAT_RS03065	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
STAT_RS03070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
STAT_RS03075	COG0596	Alpha beta hydrolase
STAT_RS03080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
STAT_RS03085	COG0668	transmembrane transport