locus-tag	class	description
BLBBGE_RS00010	COG1077	Cell shape determining protein MreB Mrl
BLBBGE_RS00015	COG1792	Involved in formation and maintenance of cell shape
BLBBGE_RS00025	COG0768	penicillin binding
BLBBGE_RS00030	COG0772	Belongs to the SEDS family
BLBBGE_RS00035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BLBBGE_RS00040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLBBGE_RS00045	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLBBGE_RS00050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BLBBGE_RS00055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLBBGE_RS00060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLBBGE_RS00065	COG0195	Participates in both transcription termination and antitermination
BLBBGE_RS00070	COG0668	transmembrane transport
BLBBGE_RS00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BLBBGE_RS00080	COG0596	Alpha beta hydrolase
BLBBGE_RS00085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLBBGE_RS00095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLBBGE_RS00105	COG0316	Belongs to the HesB IscA family
BLBBGE_RS00110	COG0719	Fe-S assembly protein
BLBBGE_RS00115	COG0396	ATPase activity
BLBBGE_RS00120	COG0719	Fe-S assembly protein
BLBBGE_RS00125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLBBGE_RS00130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLBBGE_RS00155	COG1234	tRNA 3'-trailer cleavage
BLBBGE_RS00160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLBBGE_RS00175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BLBBGE_RS00180	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BLBBGE_RS00180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLBBGE_RS00185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLBBGE_RS00190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BLBBGE_RS00195	COG0193	aminoacyl-tRNA hydrolase activity
BLBBGE_RS00205	COG0481	GTPase activity
BLBBGE_RS00210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BLBBGE_RS00220	COG0492	ferredoxin-NADP+ reductase activity
BLBBGE_RS00245	COG0259	pyridoxamine-phosphate oxidase activity
BLBBGE_RS00255	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLBBGE_RS00265	COG0653	protein targeting
BLBBGE_RS00270	COG2949	membrane
BLBBGE_RS00275	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BLBBGE_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
BLBBGE_RS00285	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLBBGE_RS00290	COG0010	Belongs to the arginase family
BLBBGE_RS00295	COG1166	arginine decarboxylase activity
BLBBGE_RS00300	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLBBGE_RS00305	COG0542	response to heat
BLBBGE_RS00310	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLBBGE_RS00330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLBBGE_RS00335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLBBGE_RS00340	COG0066	3-isopropylmalate dehydratase activity
BLBBGE_RS00355	COG0196	riboflavin kinase activity
BLBBGE_RS00370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BLBBGE_RS00375	COG0307	riboflavin synthase, alpha
BLBBGE_RS00380	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BLBBGE_RS00385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLBBGE_RS00390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLBBGE_RS00395	COG0571	ribonuclease III activity
BLBBGE_RS00405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BLBBGE_RS00410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLBBGE_RS00415	COG1187	pseudouridine synthase activity
BLBBGE_RS00425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLBBGE_RS00435	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BLBBGE_RS00455	COG1253	flavin adenine dinucleotide binding
BLBBGE_RS00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLBBGE_RS00470	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLBBGE_RS00475	COG1132	(ABC) transporter
BLBBGE_RS00480	COG0861	Integral membrane protein TerC family
BLBBGE_RS00485	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLBBGE_RS00490	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLBBGE_RS00495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLBBGE_RS00500	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BLBBGE_RS00505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLBBGE_RS00515	COG0149	triose-phosphate isomerase activity
BLBBGE_RS00525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLBBGE_RS00535	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLBBGE_RS00545	COG2226	methyltransferase
BLBBGE_RS00550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLBBGE_RS00555	COG0254	rRNA binding
BLBBGE_RS00560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLBBGE_RS00565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BLBBGE_RS00575	COG1012	belongs to the aldehyde dehydrogenase family
BLBBGE_RS00580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLBBGE_RS00585	COG0017	Asparaginyl-tRNA synthetase
BLBBGE_RS00590	COG0233	cytoplasmic translational termination
BLBBGE_RS00595	COG0528	UMP kinase activity
BLBBGE_RS00600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLBBGE_RS00605	COG0495	leucyl-tRNA aminoacylation
BLBBGE_RS00610	COG2239	Acts as a magnesium transporter
BLBBGE_RS00615	COG0564	pseudouridine synthase activity
BLBBGE_RS00625	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLBBGE_RS00640	COG0750	zinc metalloprotease
BLBBGE_RS00645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLBBGE_RS00650	COG0596	Alpha beta hydrolase
BLBBGE_RS00655	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BLBBGE_RS00665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLBBGE_RS00670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLBBGE_RS00680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BLBBGE_RS00685	COG0210	DNA helicase
BLBBGE_RS00690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLBBGE_RS00710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLBBGE_RS00710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLBBGE_RS00720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BLBBGE_RS00725	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BLBBGE_RS00730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLBBGE_RS00740	COG1418	mRNA catabolic process
BLBBGE_RS00745	COG1104	cysteine desulfurase activity
BLBBGE_RS00755	COG1053	succinate dehydrogenase
BLBBGE_RS00760	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLBBGE_RS00780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLBBGE_RS00785	COG0335	large ribosomal subunit rRNA binding
BLBBGE_RS00805	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLBBGE_RS00820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BLBBGE_RS00870	COG0081	regulation of translation
BLBBGE_RS00875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLBBGE_RS00880	COG0222	ribosome binding
BLBBGE_RS00885	COG0085	RNA polymerase activity
BLBBGE_RS00890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLBBGE_RS00900	COG0285	dihydrofolate synthase activity
BLBBGE_RS00910	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLBBGE_RS00920	COG0534	Mate efflux family protein
BLBBGE_RS00925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLBBGE_RS00935	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BLBBGE_RS00960	COG0237	dephospho-CoA kinase activity
BLBBGE_RS00965	COG1862	Preprotein translocase
BLBBGE_RS00970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLBBGE_RS00975	COG1132	(ABC) transporter
BLBBGE_RS00995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLBBGE_RS01020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BLBBGE_RS01025	COG0724	RNA recognition motif
BLBBGE_RS01035	COG1528	Iron-storage protein
BLBBGE_RS01045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLBBGE_RS01050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLBBGE_RS01055	COG0563	adenylate kinase activity
BLBBGE_RS01065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLBBGE_RS01070	COG0504	CTP synthase activity
BLBBGE_RS01075	COG0706	membrane insertase activity
BLBBGE_RS01090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLBBGE_RS01095	COG4589	Belongs to the CDS family
BLBBGE_RS01100	COG0688	phosphatidylethanolamine metabolic process
BLBBGE_RS01115	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLBBGE_RS01120	COG0052	Belongs to the universal ribosomal protein uS2 family
BLBBGE_RS01125	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLBBGE_RS01130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BLBBGE_RS01155	COG0051	transcription antitermination factor activity, RNA binding
BLBBGE_RS01165	COG0088	Forms part of the polypeptide exit tunnel
BLBBGE_RS01170	COG0089	rRNA binding
BLBBGE_RS01175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BLBBGE_RS01180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLBBGE_RS01185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLBBGE_RS01190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLBBGE_RS01195	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLBBGE_RS01205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLBBGE_RS01210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLBBGE_RS01215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLBBGE_RS01225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLBBGE_RS01230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLBBGE_RS01235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLBBGE_RS01250	COG0200	Binds to the 23S rRNA
BLBBGE_RS01255	COG0201	protein transport
BLBBGE_RS01260	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLBBGE_RS01265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLBBGE_RS01275	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLBBGE_RS01280	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLBBGE_RS01285	COG0202	RNA polymerase activity
BLBBGE_RS01290	COG0203	ribosomal protein L17
BLBBGE_RS01295	COG0148	phosphopyruvate hydratase activity
BLBBGE_RS01310	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BLBBGE_RS01315	COG1575	Belongs to the MenA family. Type 1 subfamily
BLBBGE_RS01320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLBBGE_RS01335	COG0538	isocitrate dehydrogenase activity
BLBBGE_RS01340	COG0175	sulfate reduction
BLBBGE_RS01345	COG0175	sulfate reduction
BLBBGE_RS01355	COG1045	serine acetyltransferase
BLBBGE_RS01365	COG1648	precorrin-2 dehydrogenase activity
BLBBGE_RS01365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLBBGE_RS01370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BLBBGE_RS01385	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLBBGE_RS01395	COG1774	PSP1 C-terminal conserved region
BLBBGE_RS01400	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLBBGE_RS01405	COG0557	exoribonuclease II activity
BLBBGE_RS01410	COG0297	glycogen (starch) synthase activity
BLBBGE_RS01415	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLBBGE_RS01435	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLBBGE_RS01440	COG0126	phosphoglycerate kinase activity
BLBBGE_RS01460	COG0194	GDP metabolic process
BLBBGE_RS01465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLBBGE_RS01470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLBBGE_RS01480	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLBBGE_RS01485	COG0142	geranyltranstransferase activity
BLBBGE_RS01490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLBBGE_RS01520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLBBGE_RS01525	COG0539	negative regulation of cytoplasmic translation
BLBBGE_RS01545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLBBGE_RS01550	COG0505	Belongs to the CarA family
BLBBGE_RS01560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLBBGE_RS01565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLBBGE_RS01570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLBBGE_RS01575	COG3118	belongs to the thioredoxin family
BLBBGE_RS01585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLBBGE_RS01585	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLBBGE_RS01605	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLBBGE_RS01610	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLBBGE_RS01610	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLBBGE_RS01615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLBBGE_RS01615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLBBGE_RS01625	COG0019	diaminopimelate decarboxylase activity
BLBBGE_RS01635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLBBGE_RS01640	COG2890	protein-(glutamine-N5) methyltransferase activity
BLBBGE_RS01645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLBBGE_RS01650	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLBBGE_RS01655	COG0360	Binds together with S18 to 16S ribosomal RNA
BLBBGE_RS01665	COG0359	binds to the 23S rRNA
BLBBGE_RS01670	COG1914	H( )-stimulated, divalent metal cation uptake system
BLBBGE_RS01675	COG0077	Prephenate dehydratase
BLBBGE_RS01675	COG1605	Chorismate mutase
BLBBGE_RS01685	COG0287	Prephenate dehydrogenase
BLBBGE_RS01690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BLBBGE_RS01695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLBBGE_RS01700	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLBBGE_RS01705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLBBGE_RS01710	COG0358	DNA primase activity
BLBBGE_RS01715	COG0450	alkyl hydroperoxide reductase
BLBBGE_RS01720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLBBGE_RS01725	COG0321	lipoyl(octanoyl) transferase activity
BLBBGE_RS01730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLBBGE_RS01735	COG0402	S-adenosylhomocysteine deaminase activity
BLBBGE_RS01740	COG0357	Ribosomal RNA small subunit methyltransferase G
BLBBGE_RS01745	COG0436	Aminotransferase
BLBBGE_RS01760	COG1301	dicarboxylic acid transport
BLBBGE_RS01770	COG0228	four-way junction DNA binding
BLBBGE_RS01775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLBBGE_RS01780	COG1968	undecaprenyl-diphosphatase activity
BLBBGE_RS01785	COG0187	DNA topoisomerase II activity
BLBBGE_RS01790	COG0165	Argininosuccinate lyase
BLBBGE_RS01795	COG0336	Belongs to the RNA methyltransferase TrmD family
BLBBGE_RS01800	COG1160	GTP binding
BLBBGE_RS01805	COG0632	four-way junction helicase activity
BLBBGE_RS01835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLBBGE_RS01850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLBBGE_RS01855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLBBGE_RS01860	COG0489	protein tyrosine kinase activity
BLBBGE_RS01875	COG0124	histidyl-tRNA synthetase
BLBBGE_RS01880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLBBGE_RS01895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLBBGE_RS01900	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLBBGE_RS01905	COG0772	Belongs to the SEDS family
BLBBGE_RS01910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLBBGE_RS01920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLBBGE_RS01925	COG0768	penicillin binding
BLBBGE_RS01940	COG0343	queuine tRNA-ribosyltransferase activity
BLBBGE_RS01950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLBBGE_RS01955	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLBBGE_RS01960	COG1363	Peptidase, m42
BLBBGE_RS01970	COG0805	protein transport
BLBBGE_RS01975	COG2885	chlorophyll binding
BLBBGE_RS01980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLBBGE_RS01985	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BLBBGE_RS01990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLBBGE_RS01995	COG1694	Mazg nucleotide pyrophosphohydrolase
BLBBGE_RS02005	COG0791	NLP P60 protein
BLBBGE_RS02025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLBBGE_RS02060	COG2217	Heavy metal translocating P-type atpase
BLBBGE_RS02065	COG0509	glycine decarboxylation via glycine cleavage system
BLBBGE_RS02080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLBBGE_RS02090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLBBGE_RS02095	COG0134	indole-3-glycerol-phosphate synthase activity
BLBBGE_RS02100	COG0133	tryptophan synthase activity
BLBBGE_RS02110	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLBBGE_RS02115	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLBBGE_RS02125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLBBGE_RS02135	COG0708	Exodeoxyribonuclease III
BLBBGE_RS02140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLBBGE_RS02145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BLBBGE_RS02150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLBBGE_RS02155	COG0131	Imidazoleglycerol-phosphate dehydratase
BLBBGE_RS02160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLBBGE_RS02165	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLBBGE_RS02170	COG0107	imidazoleglycerol-phosphate synthase activity
BLBBGE_RS02175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLBBGE_RS02175	COG0140	phosphoribosyl-ATP diphosphatase activity
BLBBGE_RS02180	COG0602	queuosine metabolic process
BLBBGE_RS02185	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLBBGE_RS02190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLBBGE_RS02195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLBBGE_RS02200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLBBGE_RS02205	COG0022	dehydrogenase e1 component
BLBBGE_RS02205	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLBBGE_RS02220	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLBBGE_RS02225	COG0525	valine-tRNA ligase activity
BLBBGE_RS02235	COG1704	LemA family
BLBBGE_RS02240	COG0105	UTP biosynthetic process
BLBBGE_RS02245	COG0022	dehydrogenase e1 component
BLBBGE_RS02250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLBBGE_RS02255	COG0018	arginyl-trna synthetase
BLBBGE_RS02260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLBBGE_RS02265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BLBBGE_RS02275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLBBGE_RS02280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLBBGE_RS02285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLBBGE_RS02290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLBBGE_RS02295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLBBGE_RS02305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLBBGE_RS02320	COG0617	tRNA 3'-terminal CCA addition
BLBBGE_RS02320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLBBGE_RS02320	COG0517	IMP dehydrogenase activity
BLBBGE_RS02325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BLBBGE_RS02340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLBBGE_RS02345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BLBBGE_RS02350	COG1074	ATP-dependent DNA helicase activity
BLBBGE_RS02355	COG0191	fructose-bisphosphate aldolase activity
BLBBGE_RS02360	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLBBGE_RS02365	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLBBGE_RS02365	COG0519	Catalyzes the synthesis of GMP from XMP
BLBBGE_RS02370	COG0151	Belongs to the GarS family
BLBBGE_RS02375	COG0138	bifunctional purine biosynthesis protein purh
BLBBGE_RS02380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLBBGE_RS02390	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLBBGE_RS02395	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLBBGE_RS02400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLBBGE_RS02405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLBBGE_RS02410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLBBGE_RS02415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLBBGE_RS02420	COG2255	four-way junction helicase activity
BLBBGE_RS02425	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BLBBGE_RS02430	COG0793	Belongs to the peptidase S41A family
BLBBGE_RS02435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLBBGE_RS02440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BLBBGE_RS02455	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLBBGE_RS02460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLBBGE_RS02465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLBBGE_RS02470	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BLBBGE_RS02475	COG0083	homoserine kinase activity
BLBBGE_RS02480	COG0527	aspartate kinase activity
BLBBGE_RS02480	COG0460	homoserine dehydrogenase
BLBBGE_RS02500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLBBGE_RS02505	COG0328	RNA-DNA hybrid ribonuclease activity
BLBBGE_RS02515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BLBBGE_RS02520	COG2095	MarC family integral membrane protein
BLBBGE_RS02525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLBBGE_RS02530	COG0167	dihydroorotate dehydrogenase activity
BLBBGE_RS02535	COG0442	prolyl-tRNA aminoacylation
BLBBGE_RS02540	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLBBGE_RS02545	COG0511	ligase activity, forming carbon-carbon bonds
BLBBGE_RS02550	COG0439	Biotin carboxylase
BLBBGE_RS02555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLBBGE_RS02585	COG0217	transcriptional regulatory protein
BLBBGE_RS02590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLBBGE_RS02595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BLBBGE_RS02600	COG0552	protein localization to endoplasmic reticulum
BLBBGE_RS02605	COG0326	Molecular chaperone. Has ATPase activity
BLBBGE_RS02615	COG1183	phosphatidylcholine synthase activity
BLBBGE_RS02620	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BLBBGE_RS02625	COG0445	tRNA wobble uridine modification
BLBBGE_RS02640	COG0084	hydrolase, TatD family'
BLBBGE_RS02645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLBBGE_RS02665	COG1530	ribonuclease E activity
BLBBGE_RS02675	COG1194	a g-specific adenine glycosylase
BLBBGE_RS02690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLBBGE_RS02695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLBBGE_RS02710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLBBGE_RS02720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLBBGE_RS02725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLBBGE_RS02735	COG0028	Belongs to the TPP enzyme family
BLBBGE_RS02745	COG0482	sulfurtransferase activity
BLBBGE_RS02750	COG0484	heat shock protein binding
BLBBGE_RS02755	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLBBGE_RS02760	COG0180	Tryptophanyl-tRNA synthetase
BLBBGE_RS02765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLBBGE_RS02780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLBBGE_RS02785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLBBGE_RS02790	COG0356	it plays a direct role in the translocation of protons across the membrane
BLBBGE_RS02795	COG0626	cystathionine gamma-synthase activity
BLBBGE_RS02800	COG0215	cysteine-tRNA ligase activity
BLBBGE_RS02805	COG0302	gtp cyclohydrolase
BLBBGE_RS02810	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BLBBGE_RS02815	COG1214	PFAM Peptidase M22, glycoprotease
BLBBGE_RS02820	COG0181	hydroxymethylbilane synthase activity
BLBBGE_RS02825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLBBGE_RS02860	COG0437	4 iron, 4 sulfur cluster binding
BLBBGE_RS02870	COG0612	Peptidase, M16
BLBBGE_RS02880	COG2151	metal-sulfur cluster biosynthetic enzyme
BLBBGE_RS02895	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLBBGE_RS02900	COG0542	response to heat
BLBBGE_RS02905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLBBGE_RS02910	COG0045	succinate-CoA ligase (ADP-forming) activity
BLBBGE_RS02915	COG1136	(ABC) transporter
BLBBGE_RS02935	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLBBGE_RS02945	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLBBGE_RS02955	COG1333	cytochrome c biogenesis protein
BLBBGE_RS02955	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLBBGE_RS02960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLBBGE_RS02960	COG0321	lipoyl(octanoyl) transferase activity
BLBBGE_RS02965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BLBBGE_RS02970	COG0741	lytic transglycosylase activity
BLBBGE_RS02975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLBBGE_RS02980	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLBBGE_RS02985	COG0756	dUTP diphosphatase activity
BLBBGE_RS03020	COG1522	sequence-specific DNA binding
BLBBGE_RS03035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLBBGE_RS03035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLBBGE_RS03040	COG0039	L-malate dehydrogenase activity
BLBBGE_RS03050	COG1137	ATPase activity
BLBBGE_RS03055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLBBGE_RS03060	COG1132	(ABC) transporter
BLBBGE_RS03065	COG0101	tRNA pseudouridine synthase activity
BLBBGE_RS03070	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLBBGE_RS03080	COG0251	oxidation-reduction process
BLBBGE_RS03090	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLBBGE_RS03140	COG0730	response to heat