locus-tag	class	description
INP51_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
INP51_RS00010	COG0592	DNA-directed DNA polymerase activity
INP51_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
INP51_RS00025	COG0187	DNA topoisomerase II activity
INP51_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INP51_RS00100	COG1686	Belongs to the peptidase S11 family
INP51_RS00110	COG2385	sporulation resulting in formation of a cellular spore
INP51_RS00145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INP51_RS00155	COG1956	GAF domain-containing protein
INP51_RS00165	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
INP51_RS00170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INP51_RS00175	COG2070	2-Nitropropane dioxygenase
INP51_RS00180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INP51_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS00190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INP51_RS00200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
INP51_RS00205	COG0439	Biotin carboxylase
INP51_RS00220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
INP51_RS00225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INP51_RS00230	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
INP51_RS00235	COG5002	protein histidine kinase activity
INP51_RS00240	COG0745	RESPONSE REGULATOR receiver
INP51_RS00245	COG0194	GDP metabolic process
INP51_RS00255	COG1774	PSP1 C-terminal conserved region
INP51_RS00260	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
INP51_RS00265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
INP51_RS00270	COG2715	membrane protein required for spore maturation
INP51_RS00275	COG0396	ATPase activity
INP51_RS00280	COG0719	Fe-S assembly protein
INP51_RS00285	COG0719	Fe-S assembly protein
INP51_RS00290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INP51_RS00295	COG0822	iron-sulfur transferase activity
INP51_RS00300	COG3588	fructose-bisphosphate aldolase
INP51_RS00310	COG0747	negative chemotaxis
INP51_RS00315	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
INP51_RS00330	COG1773	rubredoxin
INP51_RS00335	COG0426	domain, Protein
INP51_RS00355	COG1394	ATPase activity, coupled to movement of substances
INP51_RS00365	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
INP51_RS00400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
INP51_RS00425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INP51_RS00485	COG0457	Tetratricopeptide repeat
INP51_RS00485	COG0705	Rhomboid family
INP51_RS00490	COG2205	protein histidine kinase activity
INP51_RS00495	COG0537	adenosine 5'-monophosphoramidase activity
INP51_RS00505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
INP51_RS00520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INP51_RS00530	COG0166	Belongs to the GPI family
INP51_RS00545	COG2205	protein histidine kinase activity
INP51_RS00550	COG4935	Belongs to the peptidase S8 family
INP51_RS00550	COG1404	Belongs to the peptidase S8 family
INP51_RS00560	COG5578	integral membrane protein
INP51_RS00565	COG3842	ATPase activity
INP51_RS00570	COG3835	regulator
INP51_RS00575	COG0564	pseudouridine synthase activity
INP51_RS00615	COG0726	polysaccharide deacetylase
INP51_RS00620	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
INP51_RS00650	COG1131	(ABC) transporter
INP51_RS00660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
INP51_RS00665	COG3328	transposase activity
INP51_RS00690	COG3279	Response regulator of the LytR AlgR family
INP51_RS00695	COG0542	response to heat
INP51_RS00705	COG2226	methyltransferase
INP51_RS00715	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
INP51_RS00715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INP51_RS00735	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
INP51_RS00740	COG1074	ATP-dependent DNA helicase activity
INP51_RS00770	COG0436	Aminotransferase
INP51_RS00775	COG0426	domain, Protein
INP51_RS00790	COG4948	Mandelate Racemase Muconate Lactonizing
INP51_RS00805	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
INP51_RS00810	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
INP51_RS00815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INP51_RS00820	COG4868	Belongs to the UPF0371 family
INP51_RS00825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INP51_RS00830	COG0322	excinuclease ABC activity
INP51_RS00835	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
INP51_RS00840	COG1940	carbohydrate kinase activity
INP51_RS00855	COG4152	abc transporter atp-binding protein
INP51_RS00860	COG1668	transmembrane transport
INP51_RS00865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INP51_RS00870	COG1739	Uncharacterized protein family UPF0029
INP51_RS00875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INP51_RS00890	COG1214	PFAM Peptidase M22, glycoprotease
INP51_RS00910	COG0573	inorganic phosphate transmembrane transporter activity
INP51_RS00915	COG0581	inorganic phosphate transmembrane transporter activity
INP51_RS00920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INP51_RS00925	COG0704	Plays a role in the regulation of phosphate uptake
INP51_RS00935	COG5002	protein histidine kinase activity
INP51_RS00950	COG0058	SHG alpha-glucan phosphorylase activity
INP51_RS00955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INP51_RS00965	COG1132	(ABC) transporter
INP51_RS00970	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INP51_RS01000	COG0590	tRNA wobble adenosine to inosine editing
INP51_RS01005	COG0785	Cytochrome C biogenesis protein
INP51_RS01010	COG1247	-acetyltransferase
INP51_RS01030	COG1396	sequence-specific DNA binding
INP51_RS01040	COG2826	transposase and inactivated derivatives, IS30 family
INP51_RS01075	COG4209	transmembrane transport
INP51_RS01080	COG0395	ABC-type sugar transport system, permease component
INP51_RS01085	COG1653	transport
INP51_RS01090	COG2972	Histidine kinase
INP51_RS01095	COG2207	Transcriptional regulator
INP51_RS01095	COG4753	response regulator
INP51_RS01130	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
INP51_RS01180	COG0419	ATPase involved in DNA repair
INP51_RS01190	COG1131	(ABC) transporter
INP51_RS01195	COG1725	Transcriptional regulator
INP51_RS01200	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
INP51_RS01220	COG0386	Belongs to the glutathione peroxidase family
INP51_RS01230	COG1846	Transcriptional regulator
INP51_RS01235	COG0583	DNA-binding transcription factor activity
INP51_RS01250	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
INP51_RS01255	COG0049	tRNA binding
INP51_RS01260	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INP51_RS01265	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
INP51_RS01270	COG0006	proline dipeptidase activity
INP51_RS01280	COG1063	alcohol dehydrogenase
INP51_RS01285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
INP51_RS01290	COG0542	response to heat
INP51_RS01300	COG1846	Transcriptional regulator
INP51_RS01305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INP51_RS01310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INP51_RS01315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INP51_RS01325	COG0250	Participates in transcription elongation, termination and antitermination
INP51_RS01330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
INP51_RS01335	COG0081	regulation of translation
INP51_RS01340	COG4667	esterase of the alpha-beta hydrolase superfamily
INP51_RS01350	COG0222	ribosome binding
INP51_RS01355	COG0085	RNA polymerase activity
INP51_RS01360	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
INP51_RS01375	COG1115	amino acid carrier protein
INP51_RS01380	COG1971	Probably functions as a manganese efflux pump
INP51_RS01385	COG0726	polysaccharide deacetylase
INP51_RS01390	COG1063	alcohol dehydrogenase
INP51_RS01395	COG0156	8-amino-7-oxononanoate synthase activity
INP51_RS01400	COG1217	gtp-binding protein TYPA
INP51_RS01410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INP51_RS01415	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
INP51_RS01440	COG0653	protein targeting
INP51_RS01450	COG0366	Alpha amylase catalytic
INP51_RS01455	COG4492	Belongs to the UPF0735 family
INP51_RS01460	COG0460	homoserine dehydrogenase
INP51_RS01465	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
INP51_RS01480	COG0398	Pfam SNARE associated Golgi protein
INP51_RS01485	COG1122	ATPase activity
INP51_RS01490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP51_RS01500	COG4721	ABC-type cobalt transport system, permease component
INP51_RS01505	COG0116	Belongs to the methyltransferase superfamily
INP51_RS01505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INP51_RS01510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INP51_RS01520	COG1181	Belongs to the D-alanine--D-alanine ligase family
INP51_RS01525	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INP51_RS01545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
INP51_RS01550	COG1802	Transcriptional regulator
INP51_RS01555	COG0697	spore germination
INP51_RS01575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
INP51_RS01605	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
INP51_RS01610	COG2954	triphosphatase activity
INP51_RS01635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
INP51_RS01640	COG0218	Necessary for normal cell division and for the maintenance of normal septation
INP51_RS01645	COG1122	ATPase activity
INP51_RS01650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP51_RS01655	COG0101	tRNA pseudouridine synthase activity
INP51_RS01665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
INP51_RS01700	COG1131	(ABC) transporter
INP51_RS01715	COG1953	Uracil, thiamine, allantoin
INP51_RS01720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
INP51_RS01730	COG3257	ureidoglycine aminohydrolase activity
INP51_RS01735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
INP51_RS01740	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
INP51_RS01745	COG1620	l-lactate permease
INP51_RS01770	COG0745	RESPONSE REGULATOR receiver
INP51_RS01775	COG1609	Transcriptional regulator
INP51_RS01775	COG2207	Transcriptional regulator
INP51_RS01785	COG1653	transport
INP51_RS01790	COG4209	transmembrane transport
INP51_RS01795	COG0395	ABC-type sugar transport system, permease component
INP51_RS01800	COG3250	beta-galactosidase activity
INP51_RS01830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS01840	COG4608	Belongs to the ABC transporter superfamily
INP51_RS01850	COG1132	(ABC) transporter
INP51_RS01855	COG1132	(ABC) transporter
INP51_RS01860	COG0525	valine-tRNA ligase activity
INP51_RS01870	COG0285	dihydrofolate synthase activity
INP51_RS01890	COG2172	sigma factor antagonist activity
INP51_RS01895	COG1191	sigma factor activity
INP51_RS01925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
INP51_RS01935	COG1481	regulation of sporulation
INP51_RS01940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP51_RS01950	COG0051	transcription antitermination factor activity, RNA binding
INP51_RS01955	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
INP51_RS01970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
INP51_RS01980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
INP51_RS01990	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
INP51_RS01995	COG0255	Belongs to the universal ribosomal protein uL29 family
INP51_RS02000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
INP51_RS02005	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
INP51_RS02020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
INP51_RS02025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
INP51_RS02030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
INP51_RS02040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
INP51_RS02045	COG1841	ribosomal large subunit assembly
INP51_RS02050	COG0200	Binds to the 23S rRNA
INP51_RS02055	COG0201	protein transport
INP51_RS02060	COG0563	adenylate kinase activity
INP51_RS02075	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
INP51_RS02080	COG0601	transmembrane transport
INP51_RS02085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS02090	COG0444	Belongs to the ABC transporter superfamily
INP51_RS02095	COG4608	Belongs to the ABC transporter superfamily
INP51_RS02105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
INP51_RS02115	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
INP51_RS02125	COG0202	RNA polymerase activity
INP51_RS02130	COG0203	ribosomal protein L17
INP51_RS02135	COG1597	lipid kinase activity
INP51_RS02160	COG2508	Transcriptional regulator
INP51_RS02165	COG2884	Cell division ATP-binding protein ftsE
INP51_RS02170	COG2177	Part of the ABC transporter FtsEX involved in
INP51_RS02175	COG0793	Belongs to the peptidase S41A family
INP51_RS02185	COG1362	aminopeptidase activity
INP51_RS02190	COG1349	DNA-binding transcription factor activity
INP51_RS02200	COG1420	regulation of RNA biosynthetic process
INP51_RS02205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
INP51_RS02210	COG0443	Heat shock 70 kDa protein
INP51_RS02215	COG0484	heat shock protein binding
INP51_RS02225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
INP51_RS02230	COG1104	cysteine desulfurase activity
INP51_RS02245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INP51_RS02250	COG4472	Bacterial protein of unknown function (DUF965)
INP51_RS02265	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
INP51_RS02280	COG4122	O-methyltransferase activity
INP51_RS02285	COG0826	peptidase U32
INP51_RS02295	COG0606	chelatase, subunit chli
INP51_RS02300	COG0758	DNA mediated transformation
INP51_RS02315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
INP51_RS02320	COG0459	protein refolding
INP51_RS02335	COG0516	GMP reductase activity
INP51_RS02335	COG0517	IMP dehydrogenase activity
INP51_RS02355	COG4708	membrane
INP51_RS02360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP51_RS02365	COG0765	amino acid transport
INP51_RS02370	COG1126	abc transporter atp-binding protein
INP51_RS02375	COG0165	Argininosuccinate lyase
INP51_RS02380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
INP51_RS02395	COG0745	RESPONSE REGULATOR receiver
INP51_RS02405	COG1609	Transcriptional regulator
INP51_RS02440	COG4303	Ethanolamine ammonia lyase large subunit
INP51_RS02450	COG4816	utilization protein
INP51_RS02460	COG1012	belongs to the aldehyde dehydrogenase family
INP51_RS02460	COG1454	alcohol dehydrogenase
INP51_RS02480	COG4869	propanediol catabolic process
INP51_RS02485	COG4820	ethanolamine utilization protein (EutJ)
INP51_RS02495	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
INP51_RS02500	COG4656	Part of a membrane complex involved in electron transport
INP51_RS02510	COG3192	ethanolamine utilization protein
INP51_RS02560	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
INP51_RS02570	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
INP51_RS02575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
INP51_RS02585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
INP51_RS02600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
INP51_RS02605	COG0107	imidazoleglycerol-phosphate synthase activity
INP51_RS02610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
INP51_RS02610	COG0140	phosphoribosyl-ATP diphosphatase activity
INP51_RS02615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
INP51_RS02625	COG2033	superoxide reductase activity
INP51_RS02645	COG0514	ATP-dependent DNA helicase (RecQ)
INP51_RS02650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
INP51_RS02685	COG3711	transcriptional antiterminator
INP51_RS02690	COG1263	PTS System
INP51_RS02690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP51_RS02690	COG2190	(PTS) system
INP51_RS02695	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP51_RS02695	COG1263	PTS System
INP51_RS02700	COG1132	(ABC) transporter
INP51_RS02710	COG2972	Histidine kinase
INP51_RS02725	COG1175	transmembrane transport
INP51_RS02730	COG0395	ABC-type sugar transport system, permease component
INP51_RS02740	COG0445	tRNA wobble uridine modification
INP51_RS02810	COG1518	maintenance of DNA repeat elements
INP51_RS02815	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
INP51_RS02820	COG4974	Belongs to the 'phage' integrase family
INP51_RS02840	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
INP51_RS02850	COG1175	transmembrane transport
INP51_RS02855	COG0395	ABC-type sugar transport system, permease component
INP51_RS02860	COG2971	BadF BadG BcrA BcrD
INP51_RS02870	COG1486	melibiose metabolic process
INP51_RS02875	COG0456	acetyltransferase
INP51_RS02885	COG3876	Protein conserved in bacteria
INP51_RS02890	COG1472	Belongs to the glycosyl hydrolase 3 family
INP51_RS02895	COG2188	Transcriptional regulator
INP51_RS02910	COG4166	transmembrane transport
INP51_RS02915	COG0601	transmembrane transport
INP51_RS02920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS02925	COG0444	Belongs to the ABC transporter superfamily
INP51_RS02930	COG4608	Belongs to the ABC transporter superfamily
INP51_RS02935	COG1070	Carbohydrate kinase
INP51_RS02945	COG2207	Transcriptional regulator
INP51_RS02950	COG0745	RESPONSE REGULATOR receiver
INP51_RS02950	COG2972	Histidine kinase
INP51_RS02995	COG2972	Histidine kinase
INP51_RS03000	COG4753	response regulator
INP51_RS03000	COG2207	Transcriptional regulator
INP51_RS03010	COG3845	ABC transporter
INP51_RS03015	COG4603	Belongs to the binding-protein-dependent transport system permease family
INP51_RS03020	COG1079	Belongs to the binding-protein-dependent transport system permease family
INP51_RS03025	COG1917	Cupin 2, conserved barrel domain protein
INP51_RS03025	COG2207	Transcriptional regulator
INP51_RS03030	COG1653	transport
INP51_RS03035	COG1175	transmembrane transport
INP51_RS03040	COG0395	ABC-type sugar transport system, permease component
INP51_RS03050	COG1621	beta-fructofuranosidase activity
INP51_RS03055	COG2186	Transcriptional regulator
INP51_RS03060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
INP51_RS03065	COG3845	ABC transporter
INP51_RS03070	COG1079	Belongs to the binding-protein-dependent transport system permease family
INP51_RS03075	COG4603	Belongs to the binding-protein-dependent transport system permease family
INP51_RS03080	COG1744	ABC transporter substrate-binding protein PnrA-like
INP51_RS03090	COG4209	transmembrane transport
INP51_RS03095	COG0395	ABC-type sugar transport system, permease component
INP51_RS03100	COG1653	transport
INP51_RS03110	COG3507	Belongs to the glycosyl hydrolase 43 family
INP51_RS03115	COG3250	beta-galactosidase activity
INP51_RS03125	COG1472	Belongs to the glycosyl hydrolase 3 family
INP51_RS03130	COG1132	(ABC) transporter
INP51_RS03135	COG1132	(ABC) transporter
INP51_RS03140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
INP51_RS03145	COG0367	asparagine synthase
INP51_RS03150	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
INP51_RS03160	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
INP51_RS03190	COG1797	cobyrinic acid a,c-diamide synthase activity
INP51_RS03200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
INP51_RS03225	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP51_RS03235	COG0310	cobalt ion transport
INP51_RS03240	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
INP51_RS03245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
INP51_RS03245	COG1648	precorrin-2 dehydrogenase activity
INP51_RS03250	COG0181	hydroxymethylbilane synthase activity
INP51_RS03260	COG0113	porphobilinogen synthase activity
INP51_RS03265	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
INP51_RS03280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
INP51_RS03285	COG1876	peptidase activity
INP51_RS03305	COG0622	Phosphoesterase
INP51_RS03360	COG0254	rRNA binding
INP51_RS03365	COG3872	metal-dependent enzyme
INP51_RS03370	COG2890	protein-(glutamine-N5) methyltransferase activity
INP51_RS03375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
INP51_RS03385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INP51_RS03395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INP51_RS03410	COG0482	sulfurtransferase activity
INP51_RS03415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
INP51_RS03430	COG0149	triose-phosphate isomerase activity
INP51_RS03435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INP51_RS03445	COG2244	polysaccharide biosynthetic process
INP51_RS03450	COG1854	S-ribosylhomocysteine lyase activity
INP51_RS03455	COG2706	6-phosphogluconolactonase activity
INP51_RS03500	COG2508	Transcriptional regulator
INP51_RS03515	COG1312	Catalyzes the dehydration of D-mannonate
INP51_RS03520	COG0246	Mannitol dehydrogenase
INP51_RS03535	COG3854	ATPases associated with a variety of cellular activities
INP51_RS03575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
INP51_RS03580	COG1302	Protein conserved in bacteria
INP51_RS03585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INP51_RS03590	COG1570	exodeoxyribonuclease VII activity
INP51_RS03595	COG1722	exodeoxyribonuclease VII activity
INP51_RS03605	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INP51_RS03610	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
INP51_RS03615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
INP51_RS03620	COG1438	arginine binding
INP51_RS03625	COG0497	DNA recombination
INP51_RS03630	COG0750	zinc metalloprotease
INP51_RS03635	COG0745	RESPONSE REGULATOR receiver
INP51_RS03640	COG0297	glycogen (starch) synthase activity
INP51_RS03645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
INP51_RS03650	COG2137	regulation of response to DNA damage stimulus
INP51_RS03655	COG1418	mRNA catabolic process
INP51_RS03660	COG0252	asparaginase activity
INP51_RS03670	COG2207	Transcriptional regulator
INP51_RS03670	COG1917	Cupin 2, conserved barrel domain protein
INP51_RS03685	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
INP51_RS03690	COG0268	Binds directly to 16S ribosomal RNA
INP51_RS03700	COG0481	GTPase activity
INP51_RS03705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INP51_RS03715	COG1077	Cell shape determining protein MreB Mrl
INP51_RS03720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INP51_RS03725	COG1040	competence protein
INP51_RS03740	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
INP51_RS03755	COG1686	Belongs to the peptidase S11 family
INP51_RS03775	COG0463	Glycosyl transferase, family 2
INP51_RS03780	COG0544	peptidyl-prolyl cis-trans isomerase activity
INP51_RS03815	COG1216	Glycosyl transferase, family 2
INP51_RS03815	COG0438	transferase activity, transferring glycosyl groups
INP51_RS03820	COG1376	ErfK ybiS ycfS ynhG family protein
INP51_RS03830	COG5263	repeat protein
INP51_RS03830	COG4193	domain, Protein
INP51_RS03835	COG0463	Glycosyl transferase, family 2
INP51_RS03860	COG1091	dTDP-4-dehydrorhamnose reductase activity
INP51_RS03870	COG0189	ligase activity
INP51_RS03885	COG0463	Glycosyl transferase, family 2
INP51_RS03890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
INP51_RS03895	COG1216	Glycosyl transferase, family 2
INP51_RS03895	COG0438	transferase activity, transferring glycosyl groups
INP51_RS03900	COG1216	Glycosyl transferase, family 2
INP51_RS03910	COG1316	TRANSCRIPTIONal
INP51_RS03920	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
INP51_RS03925	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INP51_RS03930	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
INP51_RS03940	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
INP51_RS03955	COG0505	Belongs to the CarA family
INP51_RS03975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
INP51_RS03975	COG0574	Belongs to the PEP-utilizing enzyme family
INP51_RS03990	COG0745	RESPONSE REGULATOR receiver
INP51_RS03995	COG5002	protein histidine kinase activity
INP51_RS04010	COG1136	(ABC) transporter
INP51_RS04020	COG2205	protein histidine kinase activity
INP51_RS04035	COG1136	(ABC) transporter
INP51_RS04040	COG3604	Transcriptional regulator
INP51_RS04045	COG3875	lactate racemase activity
INP51_RS04090	COG1653	transport
INP51_RS04105	COG1653	transport
INP51_RS04110	COG4209	transmembrane transport
INP51_RS04115	COG0395	ABC-type sugar transport system, permease component
INP51_RS04120	COG2755	lipolytic protein G-D-S-L family
INP51_RS04130	COG1132	(ABC) transporter
INP51_RS04145	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INP51_RS04170	COG4509	Sortase family
INP51_RS04185	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
INP51_RS04190	COG0359	binds to the 23S rRNA
INP51_RS04195	COG0305	Participates in initiation and elongation during chromosome replication
INP51_RS04205	COG2221	Nitrite and sulphite reductase 4Fe-4S
INP51_RS04210	COG4862	establishment of competence for transformation
INP51_RS04235	COG0860	N-Acetylmuramoyl-L-alanine amidase
INP51_RS04240	COG0009	L-threonylcarbamoyladenylate synthase
INP51_RS04250	COG0698	ribose 5-phosphate isomerase
INP51_RS04265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
INP51_RS04270	COG2226	methyltransferase
INP51_RS04285	COG0617	tRNA 3'-terminal CCA addition
INP51_RS04295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INP51_RS04300	COG0776	regulation of translation
INP51_RS04305	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INP51_RS04330	COG0037	tRNA processing
INP51_RS04340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INP51_RS04370	COG1070	Carbohydrate kinase
INP51_RS04380	COG4974	Belongs to the 'phage' integrase family
INP51_RS04385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INP51_RS04390	COG1388	LysM domain
INP51_RS04390	COG3858	chitin binding
INP51_RS04405	COG2197	response regulator
INP51_RS04410	COG4585	Histidine kinase
INP51_RS04415	COG1131	(ABC) transporter
INP51_RS04440	COG0745	RESPONSE REGULATOR receiver
INP51_RS04455	COG2205	protein histidine kinase activity
INP51_RS04460	COG1388	LysM domain
INP51_RS04460	COG3858	chitin binding
INP51_RS04465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INP51_RS04470	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INP51_RS04475	COG0242	peptide deformylase activity
INP51_RS04485	COG2738	Putative neutral zinc metallopeptidase
INP51_RS04490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
INP51_RS04490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INP51_RS04495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
INP51_RS04500	COG0631	protein serine/threonine phosphatase activity
INP51_RS04505	COG2815	serine threonine protein kinase
INP51_RS04505	COG0515	serine threonine protein kinase
INP51_RS04515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
INP51_RS04520	COG1564	THIamine pyrophosphokinase
INP51_RS04525	COG0012	GTP binding
INP51_RS04530	COG2001	Belongs to the MraZ family
INP51_RS04545	COG0768	penicillin binding
INP51_RS04550	COG0768	penicillin binding
INP51_RS04555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
INP51_RS04560	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
INP51_RS04565	COG0772	Belongs to the SEDS family
INP51_RS04570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INP51_RS04585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
INP51_RS04600	COG1191	sigma factor activity
INP51_RS04605	COG1191	sigma factor activity
INP51_RS04610	COG1918	ferrous iron import across plasma membrane
INP51_RS04610	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INP51_RS04615	COG1904	glucuronate isomerase
INP51_RS04620	COG1609	Transcriptional regulator
INP51_RS04625	COG2721	sulfolactate sulfo-lyase activity
INP51_RS04630	COG0246	Mannitol dehydrogenase
INP51_RS04650	COG4753	response regulator
INP51_RS04650	COG2207	Transcriptional regulator
INP51_RS04655	COG4209	transmembrane transport
INP51_RS04660	COG0395	ABC-type sugar transport system, permease component
INP51_RS04670	COG3275	phosphorelay sensor kinase activity
INP51_RS04690	COG1874	Beta-galactosidase
INP51_RS04700	COG3250	beta-galactosidase activity
INP51_RS04720	COG1501	Belongs to the glycosyl hydrolase 31 family
INP51_RS04725	COG2207	Transcriptional regulator
INP51_RS04725	COG4753	response regulator
INP51_RS04730	COG2972	Histidine kinase
INP51_RS04740	COG1175	transmembrane transport
INP51_RS04745	COG0395	ABC-type sugar transport system, permease component
INP51_RS04755	COG1609	Transcriptional regulator
INP51_RS04765	COG3959	Transketolase, thiamine diphosphate binding domain
INP51_RS04770	COG3958	Transketolase
INP51_RS04775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
INP51_RS04805	COG1269	ATP hydrolysis coupled proton transport
INP51_RS04810	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INP51_RS04825	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
INP51_RS04830	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
INP51_RS04835	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
INP51_RS04840	COG1394	ATPase activity, coupled to movement of substances
INP51_RS04850	COG1653	transport
INP51_RS04860	COG2843	Capsule synthesis protein
INP51_RS04865	COG0745	RESPONSE REGULATOR receiver
INP51_RS04870	COG5002	protein histidine kinase activity
INP51_RS04875	COG1136	(ABC) transporter
INP51_RS04885	COG0768	penicillin binding
INP51_RS04890	COG0667	Aldo Keto reductase
INP51_RS04905	COG2720	vancomycin resistance protein
INP51_RS04920	COG5002	protein histidine kinase activity
INP51_RS04925	COG0745	RESPONSE REGULATOR receiver
INP51_RS04930	COG1193	negative regulation of DNA recombination
INP51_RS04935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INP51_RS04940	COG3481	metal-dependent phosphohydrolase, HD sub domain
INP51_RS04950	COG1733	regulation of RNA biosynthetic process
INP51_RS04965	COG0431	NADPH-dependent FMN reductase
INP51_RS04995	COG0426	domain, Protein
INP51_RS04995	COG1773	rubredoxin
INP51_RS05000	COG0561	phosphatase activity
INP51_RS05020	COG1573	uracil-dna glycosylase
INP51_RS05025	COG3384	dioxygenase
INP51_RS05050	COG2378	regulation of single-species biofilm formation
INP51_RS05065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INP51_RS05085	COG0720	synthase
INP51_RS05090	COG0735	belongs to the Fur family
INP51_RS05095	COG2972	Histidine kinase
INP51_RS05100	COG4753	response regulator
INP51_RS05100	COG2207	Transcriptional regulator
INP51_RS05110	COG1175	transmembrane transport
INP51_RS05115	COG0395	ABC-type sugar transport system, permease component
INP51_RS05120	COG3250	beta-galactosidase activity
INP51_RS05125	COG0786	glutamate:sodium symporter activity
INP51_RS05135	COG2721	sulfolactate sulfo-lyase activity
INP51_RS05140	COG3681	Belongs to the UPF0597 family
INP51_RS05150	COG2223	nitrite transmembrane transporter activity
INP51_RS05170	COG1653	transport
INP51_RS05175	COG1175	transmembrane transport
INP51_RS05180	COG0395	ABC-type sugar transport system, permease component
INP51_RS05195	COG1653	transport
INP51_RS05200	COG4209	transmembrane transport
INP51_RS05205	COG0395	ABC-type sugar transport system, permease component
INP51_RS05255	COG0601	transmembrane transport
INP51_RS05260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS05270	COG0444	Belongs to the ABC transporter superfamily
INP51_RS05285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INP51_RS05285	COG0512	Glutamine amidotransferase of anthranilate synthase
INP51_RS05290	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
INP51_RS05295	COG0134	indole-3-glycerol-phosphate synthase activity
INP51_RS05300	COG0135	phosphoribosylanthranilate isomerase activity
INP51_RS05305	COG0133	tryptophan synthase activity
INP51_RS05310	COG0159	tryptophan synthase activity
INP51_RS05330	COG0129	dihydroxy-acid dehydratase activity
INP51_RS05335	COG0534	Mate efflux family protein
INP51_RS05345	COG4753	response regulator
INP51_RS05345	COG2207	Transcriptional regulator
INP51_RS05360	COG4209	transmembrane transport
INP51_RS05365	COG0395	ABC-type sugar transport system, permease component
INP51_RS05400	COG2217	Heavy metal translocating P-type atpase
INP51_RS05405	COG1653	transport
INP51_RS05415	COG0395	ABC-type sugar transport system, permease component
INP51_RS05420	COG1114	Component of the transport system for branched-chain amino acids
INP51_RS05430	COG1131	(ABC) transporter
INP51_RS05435	COG1131	(ABC) transporter
INP51_RS05445	COG2972	Histidine kinase
INP51_RS05450	COG2207	Transcriptional regulator
INP51_RS05450	COG4753	response regulator
INP51_RS05460	COG1175	transmembrane transport
INP51_RS05465	COG0395	ABC-type sugar transport system, permease component
INP51_RS05470	COG1063	alcohol dehydrogenase
INP51_RS05475	COG0656	L-ascorbic acid biosynthetic process
INP51_RS05500	COG0531	amino acid
INP51_RS05505	COG1396	sequence-specific DNA binding
INP51_RS05510	COG0488	(ABC) transporter
INP51_RS05520	COG1011	Hydrolase
INP51_RS05525	COG0519	Catalyzes the synthesis of GMP from XMP
INP51_RS05540	COG1704	LemA family
INP51_RS05560	COG2252	PERMEase
INP51_RS05565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
INP51_RS05565	COG2111	Na H antiporter
INP51_RS05570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
INP51_RS05575	COG3260	NADH ubiquinone oxidoreductase 20
INP51_RS05580	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
INP51_RS05585	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
INP51_RS05585	COG3261	NADH dehydrogenase
INP51_RS05605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
INP51_RS05610	COG0298	carbon dioxide binding
INP51_RS05615	COG0409	Hydrogenase expression formation protein
INP51_RS05625	COG4753	response regulator
INP51_RS05625	COG2207	Transcriptional regulator
INP51_RS05650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INP51_RS05700	COG0521	Mo-molybdopterin cofactor biosynthetic process
INP51_RS05705	COG0725	ABC transporter, periplasmic molybdate-binding protein
INP51_RS05710	COG4149	molybdate abc transporter
INP51_RS05715	COG3842	ATPase activity
INP51_RS05725	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
INP51_RS05725	COG3608	succinylglutamate desuccinylase aspartoacylase
INP51_RS05735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INP51_RS05740	COG0210	DNA helicase
INP51_RS05745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INP51_RS05755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INP51_RS05755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INP51_RS05760	COG0237	dephospho-CoA kinase activity
INP51_RS05765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INP51_RS05775	COG2848	UPF0210 protein
INP51_RS05785	COG0280	phosphate acetyltransferase
INP51_RS05800	COG0333	Belongs to the bacterial ribosomal protein bL32 family
INP51_RS05805	COG1803	Methylglyoxal synthase
INP51_RS05815	COG0416	fatty acid biosynthetic process
INP51_RS05820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INP51_RS05825	COG0571	ribonuclease III activity
INP51_RS05830	COG1196	nuclear chromosome segregation
INP51_RS05835	COG0552	protein localization to endoplasmic reticulum
INP51_RS05845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INP51_RS05860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
INP51_RS05865	COG0336	Belongs to the RNA methyltransferase TrmD family
INP51_RS05870	COG0335	large ribosomal subunit rRNA binding
INP51_RS05875	COG0681	Belongs to the peptidase S26 family
INP51_RS05880	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
INP51_RS05885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
INP51_RS05890	COG0792	nuclease activity
INP51_RS05895	COG1496	oxidoreductase activity
INP51_RS05900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INP51_RS05915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
INP51_RS05925	COG0656	L-ascorbic acid biosynthetic process
INP51_RS05940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
INP51_RS05945	COG1151	hydroxylamine reductase activity
INP51_RS05990	COG2759	Belongs to the formate--tetrahydrofolate ligase family
INP51_RS05995	COG3404	Formiminotransferase-cyclodeaminase
INP51_RS06000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
INP51_RS06005	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
INP51_RS06020	COG2385	sporulation resulting in formation of a cellular spore
INP51_RS06025	COG1295	ribonuclease BN
INP51_RS06040	COG0328	RNA-DNA hybrid ribonuclease activity
INP51_RS06050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
INP51_RS06055	COG0828	Belongs to the bacterial ribosomal protein bS21 family
INP51_RS06060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INP51_RS06065	COG1686	Belongs to the peptidase S11 family
INP51_RS06070	COG1408	metallophosphoesterase
INP51_RS06075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
INP51_RS06095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INP51_RS06105	COG1132	(ABC) transporter
INP51_RS06120	COG1120	ATPase activity
INP51_RS06125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS06145	COG1120	ATPase activity
INP51_RS06170	COG0129	dihydroxy-acid dehydratase activity
INP51_RS06175	COG0028	Belongs to the TPP enzyme family
INP51_RS06180	COG0440	acetolactate synthase activity
INP51_RS06195	COG1053	succinate dehydrogenase
INP51_RS06215	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP51_RS06220	COG1122	ATPase activity
INP51_RS06225	COG1136	(ABC) transporter
INP51_RS06230	COG2032	superoxide dismutase activity
INP51_RS06235	COG3546	catalase activity
INP51_RS06305	COG3723	Recombinational DNA repair protein, rece pathway
INP51_RS06310	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
INP51_RS06325	COG3646	Phage regulatory protein
INP51_RS06325	COG3645	SOS response
INP51_RS06460	COG4824	toxin secretion phage lysis holin
INP51_RS06465	COG1876	peptidase activity
INP51_RS06490	COG0584	glycerophosphoryl diester phosphodiesterase
INP51_RS06495	COG0772	Belongs to the SEDS family
INP51_RS06500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INP51_RS06515	COG4176	ABC-type proline glycine betaine transport system permease component
INP51_RS06520	COG2113	Glycine betaine
INP51_RS06525	COG0402	S-adenosylhomocysteine deaminase activity
INP51_RS06530	COG1122	ATPase activity
INP51_RS06535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INP51_RS06540	COG1122	ATPase activity
INP51_RS06560	COG0726	polysaccharide deacetylase
INP51_RS06570	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
INP51_RS06580	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
INP51_RS06605	COG1175	transmembrane transport
INP51_RS06625	COG1876	peptidase activity
INP51_RS06635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
INP51_RS06640	COG0072	phenylalanine-tRNA ligase activity
INP51_RS06640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INP51_RS06645	COG0406	alpha-ribazole phosphatase activity
INP51_RS06655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
INP51_RS06665	COG0287	Prephenate dehydrogenase
INP51_RS06675	COG0495	leucyl-tRNA aminoacylation
INP51_RS06680	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
INP51_RS06685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INP51_RS06695	COG1408	metallophosphoesterase
INP51_RS06705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
INP51_RS06710	COG1561	YicC-like family, N-terminal region
INP51_RS06720	COG0194	GDP metabolic process
INP51_RS06730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INP51_RS06735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INP51_RS06740	COG1546	Belongs to the CinA family
INP51_RS06740	COG1058	Belongs to the CinA family
INP51_RS06765	COG0504	CTP synthase activity
INP51_RS06770	COG0070	glutamate synthase
INP51_RS06770	COG0069	glutamate synthase activity
INP51_RS06770	COG0067	glutamate synthase
INP51_RS06775	COG0493	'glutamate synthase
INP51_RS06790	COG0436	Aminotransferase
INP51_RS06795	COG0017	Asparaginyl-tRNA synthetase
INP51_RS06800	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
INP51_RS06815	COG1404	Belongs to the peptidase S8 family
INP51_RS06820	COG0538	isocitrate dehydrogenase activity
INP51_RS06825	COG0488	(ABC) transporter
INP51_RS06830	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
INP51_RS06835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
INP51_RS06835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
INP51_RS06840	COG2337	Toxic component of a toxin-antitoxin (TA) module
INP51_RS06845	COG0217	transcriptional regulatory protein
INP51_RS06850	COG0740	serine-type endopeptidase activity
INP51_RS06855	COG1968	undecaprenyl-diphosphatase activity
INP51_RS06875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
INP51_RS06880	COG0671	phosphoesterase, PA-phosphatase related
INP51_RS06900	COG1702	phosphate starvation-inducible protein PhoH
INP51_RS06905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
INP51_RS06915	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
INP51_RS06920	COG4224	UPF0291 protein
INP51_RS06925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INP51_RS06930	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
INP51_RS06990	COG5002	protein histidine kinase activity
INP51_RS06995	COG1136	(ABC) transporter
INP51_RS07030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
INP51_RS07040	COG1051	belongs to the nudix hydrolase family
INP51_RS07090	COG1609	Transcriptional regulator
INP51_RS07095	COG1175	transmembrane transport
INP51_RS07100	COG3833	ABC-type maltose transport systems, permease component
INP51_RS07105	COG2182	Extracellular solute-binding protein
INP51_RS07130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
INP51_RS07135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
INP51_RS07145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
INP51_RS07150	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
INP51_RS07155	COG2081	HI0933 family
INP51_RS07160	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
INP51_RS07165	COG2003	Belongs to the UPF0758 family
INP51_RS07170	COG1077	Cell shape determining protein MreB Mrl
INP51_RS07185	COG0768	penicillin binding
INP51_RS07190	COG2894	cell division
INP51_RS07205	COG1803	Methylglyoxal synthase
INP51_RS07210	COG1686	Belongs to the peptidase S11 family
INP51_RS07230	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INP51_RS07245	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
INP51_RS07255	COG0564	pseudouridine synthase activity
INP51_RS07270	COG1609	Transcriptional regulator
INP51_RS07275	COG4209	transmembrane transport
INP51_RS07280	COG0395	ABC-type sugar transport system, permease component
INP51_RS07285	COG1653	transport
INP51_RS07310	COG3250	beta-galactosidase activity
INP51_RS07315	COG4974	Belongs to the 'phage' integrase family
INP51_RS07320	COG0765	amino acid transport
INP51_RS07325	COG0765	amino acid transport
INP51_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP51_RS07335	COG1126	abc transporter atp-binding protein
INP51_RS07345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
INP51_RS07350	COG0799	negative regulation of ribosome biogenesis
INP51_RS07355	COG1713	HD superfamily hydrolase involved in NAD metabolism
INP51_RS07360	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
INP51_RS07365	COG1534	Rna-binding protein
INP51_RS07370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
INP51_RS07375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
INP51_RS07390	COG1307	EDD domain protein, DegV family
INP51_RS07405	COG0148	phosphopyruvate hydratase activity
INP51_RS07410	COG1392	Phosphate transport regulator
INP51_RS07415	COG0306	phosphate transporter
INP51_RS07425	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
INP51_RS07430	COG0037	tRNA processing
INP51_RS07450	COG0564	pseudouridine synthase activity
INP51_RS07460	COG1187	pseudouridine synthase activity
INP51_RS07465	COG2357	RelA SpoT domain protein
INP51_RS07470	COG2195	Cleaves the N-terminal amino acid of tripeptides
INP51_RS07485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
INP51_RS07490	COG0742	ribosomal rna small subunit methyltransferase
INP51_RS07495	COG1803	Methylglyoxal synthase
INP51_RS07505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INP51_RS07510	COG1461	Dihydroxyacetone kinase
INP51_RS07520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
INP51_RS07540	COG2816	NAD+ diphosphatase activity
INP51_RS07545	COG0355	proton-transporting ATP synthase activity, rotational mechanism
INP51_RS07550	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
INP51_RS07555	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
INP51_RS07560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
INP51_RS07565	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INP51_RS07570	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
INP51_RS07580	COG0356	it plays a direct role in the translocation of protons across the membrane
INP51_RS07595	COG0768	penicillin binding
INP51_RS07605	COG0826	peptidase U32
INP51_RS07615	COG2255	four-way junction helicase activity
INP51_RS07620	COG0632	four-way junction helicase activity
INP51_RS07640	COG2878	Part of a membrane complex involved in electron transport
INP51_RS07645	COG4657	Part of a membrane complex involved in electron transport
INP51_RS07650	COG4660	Part of a membrane complex involved in electron transport
INP51_RS07655	COG4659	FMN binding
INP51_RS07660	COG4658	electron transport chain
INP51_RS07665	COG4656	Part of a membrane complex involved in electron transport
INP51_RS07680	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
INP51_RS07680	COG0539	negative regulation of cytoplasmic translation
INP51_RS07685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
INP51_RS07690	COG2081	HI0933 family
INP51_RS07705	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
INP51_RS07715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
INP51_RS07720	COG0205	6-phosphofructokinase activity
INP51_RS07725	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
INP51_RS07735	COG1846	Transcriptional regulator
INP51_RS07740	COG1132	(ABC) transporter
INP51_RS07760	COG1486	melibiose metabolic process
INP51_RS07765	COG1686	Belongs to the peptidase S11 family
INP51_RS07770	COG3800	Transcriptional regulator
INP51_RS07770	COG1396	sequence-specific DNA binding
INP51_RS07775	COG3842	ATPase activity
INP51_RS07780	COG1176	ABC-type spermidine putrescine transport system, permease component I
INP51_RS07790	COG0726	polysaccharide deacetylase
INP51_RS07795	COG3158	transport of potassium into the cell
INP51_RS07800	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
INP51_RS07805	COG0360	Binds together with S18 to 16S ribosomal RNA
INP51_RS07825	COG5002	protein histidine kinase activity
INP51_RS07830	COG0745	RESPONSE REGULATOR receiver
INP51_RS07840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
INP51_RS07845	COG0557	exoribonuclease II activity
INP51_RS07850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
INP51_RS07855	COG0148	phosphopyruvate hydratase activity
INP51_RS07860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
INP51_RS07865	COG1126	abc transporter atp-binding protein
INP51_RS07870	COG0765	amino acid transport
INP51_RS07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INP51_RS07880	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
INP51_RS07900	COG5012	cobalamin binding
INP51_RS07945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INP51_RS07945	COG0551	DNA topoisomerase type I activity
INP51_RS07950	COG2116	formate transmembrane transporter activity
INP51_RS07960	COG0165	Argininosuccinate lyase
INP51_RS07970	COG0688	phosphatidylethanolamine metabolic process
INP51_RS07975	COG1183	phosphatidylcholine synthase activity
INP51_RS07985	COG1116	anion transmembrane transporter activity
INP51_RS07990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
INP51_RS07995	COG0124	histidyl-tRNA synthetase
INP51_RS08005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INP51_RS08010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INP51_RS08015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
INP51_RS08020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INP51_RS08025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
INP51_RS08025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INP51_RS08050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INP51_RS08075	COG1151	hydroxylamine reductase activity
INP51_RS08090	COG1940	carbohydrate kinase activity
INP51_RS08095	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
INP51_RS08095	COG0493	'glutamate synthase
INP51_RS08100	COG0402	S-adenosylhomocysteine deaminase activity
INP51_RS08115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INP51_RS08120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INP51_RS08125	COG0549	Belongs to the carbamate kinase family
INP51_RS08140	COG0251	oxidation-reduction process
INP51_RS08145	COG2964	Protein conserved in bacteria
INP51_RS08150	COG2502	aspartate--ammonia ligase
INP51_RS08175	COG0860	N-Acetylmuramoyl-L-alanine amidase
INP51_RS08180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INP51_RS08185	COG0187	DNA topoisomerase II activity
INP51_RS08215	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
INP51_RS08220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INP51_RS08225	COG0167	dihydroorotate dehydrogenase activity
INP51_RS08230	COG0543	2 iron, 2 sulfur cluster binding
INP51_RS08235	COG0284	orotidine-5'-phosphate decarboxylase activity
INP51_RS08240	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
INP51_RS08245	COG1278	Cold shock
INP51_RS08255	COG1307	EDD domain protein, DegV family
INP51_RS08260	COG0598	Magnesium transport protein CorA
INP51_RS08275	COG1012	belongs to the aldehyde dehydrogenase family
INP51_RS08285	COG0546	phosphoglycolate phosphatase activity
INP51_RS08300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
INP51_RS08305	COG0513	Belongs to the DEAD box helicase family
INP51_RS08310	COG2080	2 iron, 2 sulfur cluster binding
INP51_RS08310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INP51_RS08330	COG1115	amino acid carrier protein
INP51_RS08335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
INP51_RS08350	COG0295	cytidine deaminase activity
INP51_RS08355	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
INP51_RS08375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
INP51_RS08380	COG1606	tRNA processing
INP51_RS08385	COG0375	protein maturation
INP51_RS08390	COG0493	'glutamate synthase
INP51_RS08400	COG5002	protein histidine kinase activity
INP51_RS08405	COG0745	RESPONSE REGULATOR receiver
INP51_RS08415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
INP51_RS08415	COG1328	CTP reductase activity
INP51_RS08420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
INP51_RS08430	COG4509	Sortase family
INP51_RS08535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INP51_RS08540	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
INP51_RS08545	COG1307	EDD domain protein, DegV family
INP51_RS08560	COG0052	Belongs to the universal ribosomal protein uS2 family
INP51_RS08590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INP51_RS08605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INP51_RS08635	COG1959	2 iron, 2 sulfur cluster binding
INP51_RS08645	COG4509	Sortase family
INP51_RS08660	COG3266	domain, Protein
INP51_RS08660	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
INP51_RS08660	COG4932	domain protein
INP51_RS08675	COG3266	domain, Protein
INP51_RS08675	COG4932	domain protein
INP51_RS08675	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
INP51_RS08680	COG1959	2 iron, 2 sulfur cluster binding
INP51_RS08710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP51_RS08715	COG2723	6-phospho-beta-galactosidase activity
INP51_RS08720	COG1263	PTS System
INP51_RS08720	COG2190	(PTS) system
INP51_RS08720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INP51_RS08725	COG3711	transcriptional antiterminator
INP51_RS08730	COG2365	Tyrosine phosphatase family
INP51_RS08735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INP51_RS08750	COG1131	(ABC) transporter
INP51_RS08755	COG1725	Transcriptional regulator
INP51_RS08760	COG1454	alcohol dehydrogenase
INP51_RS08760	COG1012	belongs to the aldehyde dehydrogenase family
INP51_RS08770	COG2723	6-phospho-beta-galactosidase activity
INP51_RS08775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INP51_RS08780	COG2365	Tyrosine phosphatase family
INP51_RS08785	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INP51_RS08790	COG1447	Phosphotransferase system cellobiose-specific component IIA
INP51_RS08835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS08855	COG2207	Transcriptional regulator
INP51_RS08890	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INP51_RS08905	COG0542	response to heat
INP51_RS08915	COG4684	Psort location CytoplasmicMembrane, score
INP51_RS08920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
INP51_RS08925	COG0653	protein targeting
INP51_RS08930	COG1253	flavin adenine dinucleotide binding
INP51_RS08950	COG0210	DNA helicase
INP51_RS08970	COG1132	(ABC) transporter
INP51_RS08975	COG1132	(ABC) transporter
INP51_RS08980	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
INP51_RS08995	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS09005	COG1309	transcriptional regulator
INP51_RS09025	COG0596	Alpha beta hydrolase
INP51_RS09055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INP51_RS09170	COG2333	competence protein COMEC
INP51_RS09170	COG0658	competence protein
INP51_RS09180	COG2195	Cleaves the N-terminal amino acid of tripeptides
INP51_RS09185	COG1937	Protein conserved in bacteria
INP51_RS09195	COG1605	Chorismate mutase
INP51_RS09195	COG0077	Prephenate dehydratase
INP51_RS09205	COG0540	Belongs to the ATCase OTCase family
INP51_RS09225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
INP51_RS09235	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INP51_RS09240	COG0358	DNA primase activity
INP51_RS09245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
INP51_RS09260	COG0750	zinc metalloprotease
INP51_RS09270	COG0575	Belongs to the CDS family
INP51_RS09280	COG0233	cytoplasmic translational termination
INP51_RS09285	COG0528	UMP kinase activity
INP51_RS09295	COG0527	aspartate kinase activity
INP51_RS09325	COG0708	Exodeoxyribonuclease III
INP51_RS09330	COG1982	Orn Lys Arg decarboxylase major
INP51_RS09335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INP51_RS09340	COG3906	Belongs to the UPF0473 family
INP51_RS09350	COG0756	dUTP diphosphatase activity
INP51_RS09355	COG1185	polyribonucleotide nucleotidyltransferase activity
INP51_RS09360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
INP51_RS09370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS09380	COG0800	Aldolase
INP51_RS09385	COG1414	Transcriptional regulator
INP51_RS09395	COG0363	glucosamine-6-phosphate deaminase activity
INP51_RS09400	COG0562	UDP-galactopyranose mutase
INP51_RS09405	COG4496	protein, YerC YecD
INP51_RS09420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INP51_RS09425	COG0726	polysaccharide deacetylase
INP51_RS09470	COG0488	(ABC) transporter
INP51_RS09475	COG1368	sulfuric ester hydrolase activity
INP51_RS09485	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
INP51_RS09490	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
INP51_RS09495	COG1187	pseudouridine synthase activity
INP51_RS09520	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
INP51_RS09525	COG0372	Belongs to the citrate synthase family
INP51_RS09530	COG0628	permease
INP51_RS09535	COG0640	Transcriptional regulator
INP51_RS09540	COG0436	Aminotransferase
INP51_RS09560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INP51_RS09570	COG3608	succinylglutamate desuccinylase aspartoacylase
INP51_RS09570	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
INP51_RS09580	COG0709	Synthesizes selenophosphate from selenide and ATP
INP51_RS09615	COG1254	Belongs to the acylphosphatase family
INP51_RS09620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INP51_RS09630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INP51_RS09640	COG0215	cysteine-tRNA ligase activity
INP51_RS09645	COG1045	serine acetyltransferase
INP51_RS09655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
INP51_RS09660	COG1215	transferase activity, transferring glycosyl groups
INP51_RS09665	COG1194	a g-specific adenine glycosylase
INP51_RS09680	COG1490	D-aminoacyl-tRNA deacylase activity
INP51_RS09685	COG1393	Belongs to the ArsC family
INP51_RS09695	COG0577	efflux transmembrane transporter activity
INP51_RS09705	COG1136	(ABC) transporter
INP51_RS09715	COG0196	riboflavin kinase activity
INP51_RS09720	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
INP51_RS09725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
INP51_RS09730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
INP51_RS09735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
INP51_RS09745	COG2740	Nucleic-acid-binding protein implicated in transcription termination
INP51_RS09750	COG0195	Participates in both transcription termination and antitermination
INP51_RS09755	COG0779	Required for maturation of 30S ribosomal subunits
INP51_RS09760	COG0668	transmembrane transport
INP51_RS09770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
INP51_RS09775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
INP51_RS09785	COG0343	queuine tRNA-ribosyltransferase activity
INP51_RS09800	COG0457	Tetratricopeptide repeat
INP51_RS09800	COG0463	Glycosyl transferase, family 2
INP51_RS09805	COG1979	alcohol dehydrogenase
INP51_RS09820	COG2207	Transcriptional regulator
INP51_RS09835	COG1882	Formate acetyltransferase
INP51_RS09840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INP51_RS09845	COG1959	2 iron, 2 sulfur cluster binding
INP51_RS09860	COG0443	Heat shock 70 kDa protein
INP51_RS09870	COG2207	Transcriptional regulator
INP51_RS09870	COG4753	response regulator
INP51_RS09875	COG2972	Histidine kinase
INP51_RS09885	COG0395	ABC-type sugar transport system, permease component
INP51_RS09910	COG1132	(ABC) transporter
INP51_RS09915	COG1132	(ABC) transporter
INP51_RS09920	COG0235	Class ii aldolase
INP51_RS09925	COG4806	L-rhamnose isomerase
INP51_RS09930	COG1070	Carbohydrate kinase
INP51_RS09945	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
INP51_RS09955	COG1811	Na channel or pump
INP51_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS09965	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
INP51_RS09975	COG2333	competence protein COMEC
INP51_RS09975	COG0658	competence protein
INP51_RS09990	COG0745	RESPONSE REGULATOR receiver
INP51_RS09995	COG1555	photosystem II stabilization
INP51_RS09995	COG1596	polysaccharide export
INP51_RS10005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
INP51_RS10010	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
INP51_RS10015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
INP51_RS10020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
INP51_RS10055	COG3426	butyrate kinase activity
INP51_RS10060	COG0280	phosphate acetyltransferase
INP51_RS10075	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
INP51_RS10075	COG0674	pyruvate-flavodoxin oxidoreductase activity
INP51_RS10090	COG0583	DNA-binding transcription factor activity
INP51_RS10100	COG1695	Transcriptional regulator
INP51_RS10135	COG1082	Xylose isomerase domain protein TIM barrel
INP51_RS10140	COG0673	inositol 2-dehydrogenase activity
INP51_RS10150	COG1012	belongs to the aldehyde dehydrogenase family
INP51_RS10155	COG3962	Belongs to the TPP enzyme family
INP51_RS10160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS10175	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INP51_RS10185	COG1653	transport
INP51_RS10190	COG0395	ABC-type sugar transport system, permease component
INP51_RS10195	COG4209	transmembrane transport
INP51_RS10210	COG0066	3-isopropylmalate dehydratase activity
INP51_RS10215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
INP51_RS10225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
INP51_RS10240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INP51_RS10245	COG0095	Lipoate-protein ligase
INP51_RS10250	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
INP51_RS10260	COG0509	glycine decarboxylation via glycine cleavage system
INP51_RS10270	COG0436	Aminotransferase
INP51_RS10280	COG1349	DNA-binding transcription factor activity
INP51_RS10285	COG2610	gluconate transmembrane transporter activity
INP51_RS10290	COG3395	kinase activity
INP51_RS10295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
INP51_RS10300	COG0584	glycerophosphoryl diester phosphodiesterase
INP51_RS10305	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
INP51_RS10350	COG4608	Belongs to the ABC transporter superfamily
INP51_RS10355	COG0444	Belongs to the ABC transporter superfamily
INP51_RS10360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS10365	COG0601	transmembrane transport
INP51_RS10370	COG0747	negative chemotaxis
INP51_RS10385	COG1172	Belongs to the binding-protein-dependent transport system permease family
INP51_RS10390	COG1129	ABC transporter
INP51_RS10420	COG1472	Belongs to the glycosyl hydrolase 3 family
INP51_RS10425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
INP51_RS10435	COG0069	glutamate synthase activity
INP51_RS10455	COG1120	ATPase activity
INP51_RS10460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS10475	COG2226	methyltransferase
INP51_RS10480	COG1760	l-serine dehydratase
INP51_RS10485	COG1760	l-serine dehydratase
INP51_RS10495	COG0395	ABC-type sugar transport system, permease component
INP51_RS10500	COG4209	transmembrane transport
INP51_RS10510	COG5520	Belongs to the glycosyl hydrolase 30 family
INP51_RS10520	COG2972	Histidine kinase
INP51_RS10535	COG3408	Glycogen debranching enzyme
INP51_RS10540	COG0395	ABC-type sugar transport system, permease component
INP51_RS10545	COG4209	transmembrane transport
INP51_RS10550	COG1653	transport
INP51_RS10555	COG2207	Transcriptional regulator
INP51_RS10590	COG0765	amino acid transport
INP51_RS10595	COG1126	abc transporter atp-binding protein
INP51_RS10605	COG1288	antiporter activity
INP51_RS10620	COG1653	transport
INP51_RS10625	COG1486	melibiose metabolic process
INP51_RS10650	COG1691	(AIR) carboxylase
INP51_RS10685	COG0789	Transcriptional regulator
INP51_RS10685	COG4978	Transcriptional regulator
INP51_RS10690	COG1316	TRANSCRIPTIONal
INP51_RS10695	COG4989	oxidoreductase activity
INP51_RS10700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INP51_RS10705	COG0395	ABC-type sugar transport system, permease component
INP51_RS10710	COG1175	transmembrane transport
INP51_RS10715	COG1653	transport
INP51_RS10730	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS10745	COG1129	ABC transporter
INP51_RS10760	COG2972	Histidine kinase
INP51_RS10765	COG4753	response regulator
INP51_RS10765	COG2207	Transcriptional regulator
INP51_RS10775	COG2068	MobA-Related Protein
INP51_RS10780	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INP51_RS10795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
INP51_RS10820	COG0523	cobalamin synthesis protein
INP51_RS10845	COG0436	Aminotransferase
INP51_RS10855	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INP51_RS10870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INP51_RS10875	COG3959	Transketolase, thiamine diphosphate binding domain
INP51_RS10880	COG3833	ABC-type maltose transport systems, permease component
INP51_RS10905	COG0395	ABC-type sugar transport system, permease component
INP51_RS10910	COG1175	transmembrane transport
INP51_RS10925	COG1609	Transcriptional regulator
INP51_RS10970	COG2972	Histidine kinase
INP51_RS10975	COG2207	Transcriptional regulator
INP51_RS10975	COG4753	response regulator
INP51_RS11010	COG1285	pathogenesis
INP51_RS11025	COG3279	Response regulator of the LytR AlgR family
INP51_RS11035	COG1192	Involved in chromosome partitioning
INP51_RS11105	COG0791	NLP P60 protein
INP51_RS11105	COG0741	lytic transglycosylase activity
INP51_RS11120	COG0551	DNA topoisomerase type I activity
INP51_RS11120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INP51_RS11140	COG3344	reverse transcriptase
INP51_RS11185	COG3843	relaxase mobilization nuclease domain protein
INP51_RS11200	COG0798	PFAM Bile acid sodium symporter
INP51_RS11280	COG1653	transport
INP51_RS11285	COG0395	ABC-type sugar transport system, permease component
INP51_RS11290	COG4209	transmembrane transport
INP51_RS11295	COG2207	Transcriptional regulator
INP51_RS11300	COG2972	Histidine kinase
INP51_RS11320	COG1609	Transcriptional regulator
INP51_RS11325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INP51_RS11340	COG3250	beta-galactosidase activity
INP51_RS11345	COG0395	ABC-type sugar transport system, permease component
INP51_RS11350	COG1175	transmembrane transport
INP51_RS11360	COG0642	Histidine kinase
INP51_RS11360	COG5002	protein histidine kinase activity
INP51_RS11365	COG0745	RESPONSE REGULATOR receiver
INP51_RS11375	COG1696	Membrane protein involved in D-alanine export
INP51_RS11385	COG0019	diaminopimelate decarboxylase activity
INP51_RS11400	COG1461	Dihydroxyacetone kinase
INP51_RS11405	COG2376	Dihydroxyacetone kinase
INP51_RS11440	COG3681	Belongs to the UPF0597 family
INP51_RS11450	COG3250	beta-galactosidase activity
INP51_RS11460	COG0395	ABC-type sugar transport system, permease component
INP51_RS11465	COG1175	transmembrane transport
INP51_RS11475	COG4753	response regulator
INP51_RS11475	COG2207	Transcriptional regulator
INP51_RS11480	COG2972	Histidine kinase
INP51_RS11485	COG3246	L-lysine catabolic process to acetate
INP51_RS11515	COG1874	Beta-galactosidase
INP51_RS11530	COG0395	ABC-type sugar transport system, permease component
INP51_RS11535	COG4209	transmembrane transport
INP51_RS11540	COG2972	Histidine kinase
INP51_RS11545	COG2204	response regulator
INP51_RS11550	COG1653	transport
INP51_RS11575	COG1609	Transcriptional regulator
INP51_RS11585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
INP51_RS11595	COG1917	Cupin 2, conserved barrel domain protein
INP51_RS11595	COG2207	Transcriptional regulator
INP51_RS11605	COG3279	Response regulator of the LytR AlgR family
INP51_RS11635	COG2364	Membrane
INP51_RS11640	COG1454	alcohol dehydrogenase
INP51_RS11645	COG3192	ethanolamine utilization protein
INP51_RS11655	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
INP51_RS11660	COG4603	Belongs to the binding-protein-dependent transport system permease family
INP51_RS11670	COG3845	ABC transporter
INP51_RS11675	COG1744	ABC transporter substrate-binding protein PnrA-like
INP51_RS11685	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
INP51_RS11690	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
INP51_RS11700	COG1349	DNA-binding transcription factor activity
INP51_RS11705	COG0191	fructose-bisphosphate aldolase activity
INP51_RS11710	COG0667	Aldo Keto reductase
INP51_RS11725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS11735	COG4753	response regulator
INP51_RS11735	COG2207	Transcriptional regulator
INP51_RS11740	COG2972	Histidine kinase
INP51_RS11740	COG0745	RESPONSE REGULATOR receiver
INP51_RS11745	COG0395	ABC-type sugar transport system, permease component
INP51_RS11750	COG1175	transmembrane transport
INP51_RS11755	COG1653	transport
INP51_RS11765	COG0673	inositol 2-dehydrogenase activity
INP51_RS11770	COG0673	inositol 2-dehydrogenase activity
INP51_RS11780	COG0395	ABC-type sugar transport system, permease component
INP51_RS11785	COG4209	transmembrane transport
INP51_RS11800	COG0457	Tetratricopeptide repeat
INP51_RS11805	COG0395	ABC-type sugar transport system, permease component
INP51_RS11825	COG2207	Transcriptional regulator
INP51_RS11825	COG3708	Transcriptional regulator
INP51_RS11830	COG2207	Transcriptional regulator
INP51_RS11835	COG0673	inositol 2-dehydrogenase activity
INP51_RS11845	COG0395	ABC-type sugar transport system, permease component
INP51_RS11850	COG4209	transmembrane transport
INP51_RS11855	COG1653	transport
INP51_RS11865	COG0457	Tetratricopeptide repeat
INP51_RS11870	COG3681	Belongs to the UPF0597 family
INP51_RS11880	COG1053	succinate dehydrogenase
INP51_RS11890	COG4608	Belongs to the ABC transporter superfamily
INP51_RS11895	COG0444	Belongs to the ABC transporter superfamily
INP51_RS11900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INP51_RS11905	COG0601	transmembrane transport
INP51_RS11910	COG0747	negative chemotaxis
INP51_RS11940	COG0395	ABC-type sugar transport system, permease component
INP51_RS11950	COG1609	Transcriptional regulator
INP51_RS11970	COG1472	Belongs to the glycosyl hydrolase 3 family
INP51_RS11980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
INP51_RS11990	COG3250	beta-galactosidase activity
INP51_RS11995	COG0395	ABC-type sugar transport system, permease component
INP51_RS12000	COG1175	transmembrane transport
INP51_RS12045	COG2721	sulfolactate sulfo-lyase activity
INP51_RS12050	COG0275	rRNA processing
INP51_RS12065	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
INP51_RS12070	COG1172	Belongs to the binding-protein-dependent transport system permease family
INP51_RS12075	COG1129	ABC transporter
INP51_RS12090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS12100	COG0395	ABC-type sugar transport system, permease component
INP51_RS12105	COG1175	transmembrane transport
INP51_RS12115	COG2207	Transcriptional regulator
INP51_RS12115	COG0662	Cupin 2, conserved barrel domain protein
INP51_RS12120	COG2972	Histidine kinase
INP51_RS12130	COG0395	ABC-type sugar transport system, permease component
INP51_RS12135	COG1175	transmembrane transport
INP51_RS12145	COG2972	Histidine kinase
INP51_RS12150	COG2207	Transcriptional regulator
INP51_RS12150	COG4753	response regulator
INP51_RS12155	COG2390	Transcriptional regulator
INP51_RS12160	COG5564	TIM-barrel signal transduction protein
INP51_RS12170	COG5564	TIM-barrel signal transduction protein
INP51_RS12175	COG1850	ribulose-bisphosphate carboxylase activity
INP51_RS12200	COG4753	response regulator
INP51_RS12200	COG2207	Transcriptional regulator
INP51_RS12205	COG3275	phosphorelay sensor kinase activity
INP51_RS12210	COG0395	ABC-type sugar transport system, permease component
INP51_RS12215	COG4209	transmembrane transport
INP51_RS12220	COG1653	transport
INP51_RS12230	COG2271	Major facilitator Superfamily
INP51_RS12235	COG5598	trimethylamine methyltransferase
INP51_RS12240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS12270	COG1063	alcohol dehydrogenase
INP51_RS12280	COG1609	Transcriptional regulator
INP51_RS12285	COG0644	oxidoreductase
INP51_RS12290	COG0673	inositol 2-dehydrogenase activity
INP51_RS12305	COG1486	melibiose metabolic process
INP51_RS12310	COG1073	alpha beta
INP51_RS12320	COG0395	ABC-type sugar transport system, permease component
INP51_RS12325	COG4209	transmembrane transport
INP51_RS12330	COG1653	transport
INP51_RS12335	COG2197	response regulator
INP51_RS12340	COG3275	phosphorelay sensor kinase activity
INP51_RS12355	COG1175	transmembrane transport
INP51_RS12365	COG0673	inositol 2-dehydrogenase activity
INP51_RS12375	COG1609	Transcriptional regulator
INP51_RS12395	COG2207	Transcriptional regulator
INP51_RS12400	COG2972	Histidine kinase
INP51_RS12405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
INP51_RS12410	COG0395	ABC-type sugar transport system, permease component
INP51_RS12425	COG0534	Mate efflux family protein
INP51_RS12450	COG0395	ABC-type sugar transport system, permease component
INP51_RS12460	COG3279	Response regulator of the LytR AlgR family
INP51_RS12465	COG2972	Histidine kinase
INP51_RS12470	COG1082	Xylose isomerase domain protein TIM barrel
INP51_RS12475	COG1063	alcohol dehydrogenase
INP51_RS12480	COG2972	Histidine kinase
INP51_RS12485	COG2207	Transcriptional regulator
INP51_RS12485	COG4753	response regulator
INP51_RS12495	COG0395	ABC-type sugar transport system, permease component
INP51_RS12500	COG1175	transmembrane transport
INP51_RS12510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INP51_RS12515	COG2188	Transcriptional regulator
INP51_RS12520	COG2222	sugar isomerase
INP51_RS12530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS12535	COG0395	ABC-type sugar transport system, permease component
INP51_RS12540	COG1175	transmembrane transport
INP51_RS12545	COG1653	transport
INP51_RS12580	COG1472	Belongs to the glycosyl hydrolase 3 family
INP51_RS12600	COG1501	Belongs to the glycosyl hydrolase 31 family
INP51_RS12605	COG0395	ABC-type sugar transport system, permease component
INP51_RS12655	COG1175	transmembrane transport
INP51_RS12660	COG1653	transport
INP51_RS12695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
INP51_RS12700	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS12705	COG1079	Belongs to the binding-protein-dependent transport system permease family
INP51_RS12710	COG4603	Belongs to the binding-protein-dependent transport system permease family
INP51_RS12715	COG3845	ABC transporter
INP51_RS12720	COG1744	ABC transporter substrate-binding protein PnrA-like
INP51_RS12745	COG1501	Belongs to the glycosyl hydrolase 31 family
INP51_RS12750	COG0395	ABC-type sugar transport system, permease component
INP51_RS12755	COG1175	transmembrane transport
INP51_RS12760	COG1653	transport
INP51_RS12770	COG4753	response regulator
INP51_RS12770	COG2207	Transcriptional regulator
INP51_RS12805	COG2197	response regulator
INP51_RS12815	COG0395	ABC-type sugar transport system, permease component
INP51_RS12820	COG1175	transmembrane transport
INP51_RS12830	COG0673	inositol 2-dehydrogenase activity
INP51_RS12855	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS12865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
INP51_RS12885	COG1216	Glycosyl transferase, family 2
INP51_RS12900	COG0297	glycogen (starch) synthase activity
INP51_RS12910	COG0562	UDP-galactopyranose mutase
INP51_RS12930	COG3944	biosynthesis protein
INP51_RS12945	COG1079	Belongs to the binding-protein-dependent transport system permease family
INP51_RS12950	COG4603	Belongs to the binding-protein-dependent transport system permease family
INP51_RS12955	COG3845	ABC transporter
INP51_RS12985	COG0395	ABC-type sugar transport system, permease component
INP51_RS12990	COG1175	transmembrane transport
INP51_RS12995	COG1653	transport
INP51_RS13000	COG0673	inositol 2-dehydrogenase activity
INP51_RS13015	COG1442	glycosyl transferase family 8
INP51_RS13020	COG1442	glycosyl transferase family 8
INP51_RS13030	COG0667	Aldo Keto reductase
INP51_RS13195	COG3645	SOS response
INP51_RS13195	COG3646	Phage regulatory protein
INP51_RS13225	COG3723	Recombinational DNA repair protein, rece pathway
INP51_RS13275	COG0582	viral genome integration into host DNA
INP51_RS13320	COG1917	Cupin 2, conserved barrel domain protein
INP51_RS13330	COG0395	ABC-type sugar transport system, permease component
INP51_RS13335	COG1175	transmembrane transport
INP51_RS13345	COG2207	Transcriptional regulator
INP51_RS13345	COG4753	response regulator
INP51_RS13350	COG2972	Histidine kinase
INP51_RS13355	COG1132	(ABC) transporter
INP51_RS13360	COG1132	(ABC) transporter
INP51_RS13365	COG0024	Methionine aminopeptidase
INP51_RS13420	COG3958	Transketolase
INP51_RS13425	COG3959	Transketolase, thiamine diphosphate binding domain
INP51_RS13435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
INP51_RS13445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INP51_RS13470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
INP51_RS13480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
INP51_RS13495	COG1802	Transcriptional regulator
INP51_RS13530	COG1876	peptidase activity
INP51_RS13535	COG2508	Transcriptional regulator
INP51_RS13555	COG1454	alcohol dehydrogenase
INP51_RS13565	COG1733	regulation of RNA biosynthetic process
INP51_RS13580	COG1461	Dihydroxyacetone kinase
INP51_RS13605	COG0523	cobalamin synthesis protein
INP51_RS13615	COG1309	transcriptional regulator
INP51_RS13630	COG1132	(ABC) transporter
INP51_RS13660	COG0519	Catalyzes the synthesis of GMP from XMP
INP51_RS13670	COG2340	Cysteine-rich secretory protein family
INP51_RS13680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS13685	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS13690	COG1120	ATPase activity
INP51_RS13705	COG1592	Rubrerythrin
INP51_RS13725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INP51_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
INP51_RS13740	COG2895	sulfate adenylyltransferase (ATP) activity
INP51_RS13745	COG0175	sulfate reduction
INP51_RS13760	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
INP51_RS13775	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
INP51_RS13780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
INP51_RS13815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
INP51_RS13820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
INP51_RS13825	COG1234	tRNA 3'-trailer cleavage
INP51_RS13830	COG2357	RelA SpoT domain protein
INP51_RS13990	COG3645	SOS response
INP51_RS13990	COG3646	Phage regulatory protein
INP51_RS14020	COG3723	Recombinational DNA repair protein, rece pathway
INP51_RS14105	COG0582	viral genome integration into host DNA
INP51_RS14120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
INP51_RS14120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
INP51_RS14130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
INP51_RS14135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
INP51_RS14140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
INP51_RS14155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INP51_RS14160	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
INP51_RS14165	COG4717	serine-type aminopeptidase activity
INP51_RS14175	COG0017	Asparaginyl-tRNA synthetase
INP51_RS14180	COG1051	belongs to the nudix hydrolase family
INP51_RS14200	COG3973	AAA domain
INP51_RS14220	COG2183	response to ionizing radiation
INP51_RS14225	COG1362	aminopeptidase activity
INP51_RS14230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
INP51_RS14235	COG1522	sequence-specific DNA binding
INP51_RS14240	COG1924	4 iron, 4 sulfur cluster binding
INP51_RS14245	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
INP51_RS14250	COG0484	heat shock protein binding
INP51_RS14270	COG1381	Involved in DNA repair and RecF pathway recombination
INP51_RS14275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
INP51_RS14295	COG0488	(ABC) transporter
INP51_RS14305	COG0281	malic enzyme
INP51_RS14325	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
INP51_RS14335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
INP51_RS14360	COG1937	Protein conserved in bacteria
INP51_RS14375	COG0463	Glycosyl transferase, family 2
INP51_RS14385	COG1363	Peptidase, m42
INP51_RS14395	COG1528	Iron-storage protein
INP51_RS14410	COG1120	ATPase activity
INP51_RS14415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS14425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
INP51_RS14430	COG2188	Transcriptional regulator
INP51_RS14435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
INP51_RS14440	COG0395	ABC-type sugar transport system, permease component
INP51_RS14445	COG1175	transmembrane transport
INP51_RS14450	COG1653	transport
INP51_RS14455	COG2222	sugar isomerase
INP51_RS14460	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INP51_RS14480	COG0395	ABC-type sugar transport system, permease component
INP51_RS14485	COG4209	transmembrane transport
INP51_RS14505	COG1349	DNA-binding transcription factor activity
INP51_RS14520	COG0071	Belongs to the small heat shock protein (HSP20) family
INP51_RS14565	COG0494	nUDIX hydrolase
INP51_RS14585	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INP51_RS14600	COG0395	ABC-type sugar transport system, permease component
INP51_RS14605	COG1175	transmembrane transport
INP51_RS14610	COG1653	transport
INP51_RS14620	COG2972	Histidine kinase
INP51_RS14625	COG2207	Transcriptional regulator
INP51_RS14625	COG4753	response regulator
INP51_RS14635	COG0588	phosphoglycerate mutase activity
INP51_RS14640	COG0038	chloride channel
INP51_RS14650	COG1131	(ABC) transporter
INP51_RS14665	COG5598	trimethylamine methyltransferase
INP51_RS14670	COG1082	Xylose isomerase domain protein TIM barrel
INP51_RS14675	COG2271	Major facilitator Superfamily
INP51_RS14690	COG4176	ABC-type proline glycine betaine transport system permease component
INP51_RS14695	COG4175	Glycine betaine
INP51_RS14695	COG0517	IMP dehydrogenase activity
INP51_RS14705	COG0395	ABC-type sugar transport system, permease component
INP51_RS14710	COG1175	transmembrane transport
INP51_RS14720	COG4753	response regulator
INP51_RS14720	COG2207	Transcriptional regulator
INP51_RS14725	COG2972	Histidine kinase
INP51_RS14735	COG0583	DNA-binding transcription factor activity
INP51_RS14740	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
INP51_RS14760	COG0446	pyridine nucleotide-disulphide oxidoreductase
INP51_RS14765	COG2723	6-phospho-beta-galactosidase activity
INP51_RS14770	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INP51_RS14780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INP51_RS14810	COG0402	S-adenosylhomocysteine deaminase activity
INP51_RS14820	COG3383	formate dehydrogenase (NAD+) activity
INP51_RS14825	COG0303	'Molybdopterin
INP51_RS14840	COG0746	molybdenum cofactor guanylyltransferase activity
INP51_RS14850	COG0395	ABC-type sugar transport system, permease component
INP51_RS14855	COG1175	transmembrane transport
INP51_RS14885	COG2192	nodulation
INP51_RS14940	COG1131	(ABC) transporter
INP51_RS14950	COG0402	S-adenosylhomocysteine deaminase activity
INP51_RS14955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
INP51_RS15020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INP51_RS15020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INP51_RS15025	COG0582	viral genome integration into host DNA
INP51_RS15070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
INP51_RS15100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
INP51_RS15110	COG4268	DNA restriction-modification system
INP51_RS15115	COG1401	restriction endodeoxyribonuclease activity
INP51_RS15120	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
INP51_RS15130	COG0732	type I restriction modification DNA specificity domain
INP51_RS15135	COG4974	Belongs to the 'phage' integrase family
INP51_RS15150	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
INP51_RS15175	COG0741	lytic transglycosylase activity
INP51_RS15175	COG0791	NLP P60 protein
INP51_RS15180	COG4509	Sortase family
INP51_RS15255	COG0827	DNA restriction-modification system
INP51_RS15285	COG1192	Involved in chromosome partitioning
INP51_RS15310	COG0701	Predicted permease
INP51_RS15325	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INP51_RS15330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
INP51_RS15335	COG2070	2-Nitropropane dioxygenase
INP51_RS15340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INP51_RS15355	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
INP51_RS15380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INP51_RS15395	COG2996	Protein conserved in bacteria
INP51_RS15415	COG2002	toxin-antitoxin pair type II binding
INP51_RS15420	COG1876	peptidase activity
INP51_RS15425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
INP51_RS15440	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
INP51_RS15440	COG1918	ferrous iron import across plasma membrane
INP51_RS15455	COG2217	Heavy metal translocating P-type atpase
INP51_RS15460	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
INP51_RS15465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INP51_RS15470	COG1120	ATPase activity
INP51_RS15485	COG2233	PERMEase
INP51_RS15490	COG1410	methionine synthase
INP51_RS15490	COG0646	methionine synthase
INP51_RS15500	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INP51_RS15515	COG0523	cobalamin synthesis protein
INP51_RS15520	COG0778	Nitroreductase
INP51_RS15525	COG3842	ATPase activity
INP51_RS15540	COG0673	inositol 2-dehydrogenase activity
INP51_RS15555	COG0673	inositol 2-dehydrogenase activity
INP51_RS15560	COG1082	Xylose isomerase domain protein TIM barrel
INP51_RS15565	COG2207	Transcriptional regulator
INP51_RS15565	COG1917	Cupin 2, conserved barrel domain protein
INP51_RS15580	COG2207	Transcriptional regulator
INP51_RS15580	COG3708	Transcriptional regulator
INP51_RS15585	COG0395	ABC-type sugar transport system, permease component
INP51_RS15590	COG1175	transmembrane transport
INP51_RS15600	COG0673	inositol 2-dehydrogenase activity
INP51_RS15625	COG0084	hydrolase, TatD family'
INP51_RS15630	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INP51_RS15630	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INP51_RS15640	COG1592	Rubrerythrin
INP51_RS15640	COG1773	rubredoxin
INP51_RS15645	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
INP51_RS15650	COG4086	secreted protein
INP51_RS15655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
INP51_RS15665	COG0058	SHG alpha-glucan phosphorylase activity
INP51_RS15670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
INP51_RS15680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
INP51_RS15685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
INP51_RS15690	COG0656	L-ascorbic acid biosynthetic process
INP51_RS15695	COG1126	abc transporter atp-binding protein
INP51_RS15700	COG0765	amino acid transport
INP51_RS15710	COG1464	Belongs to the NlpA lipoprotein family
INP51_RS15715	COG2011	ABC-type metal ion transport system permease component
INP51_RS15720	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
INP51_RS15745	COG1687	branched-chain amino acid
INP51_RS15750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
INP51_RS15770	COG0583	DNA-binding transcription factor activity
INP51_RS15775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
INP51_RS15815	COG0657	acetylesterase activity
INP51_RS15830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INP51_RS15835	COG0494	nUDIX hydrolase
INP51_RS15845	COG3546	catalase activity
INP51_RS15910	COG0789	Transcriptional regulator
INP51_RS15920	COG0395	ABC-type sugar transport system, permease component
INP51_RS15925	COG4209	transmembrane transport
INP51_RS15930	COG3275	phosphorelay sensor kinase activity
INP51_RS15935	COG2207	Transcriptional regulator
INP51_RS15940	COG1653	transport
INP51_RS15945	COG0531	amino acid
INP51_RS15965	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
INP51_RS15975	COG1475	DNA binding
INP51_RS15980	COG1192	Involved in chromosome partitioning
INP51_RS16005	COG1131	(ABC) transporter
INP51_RS16010	COG0357	Ribosomal RNA small subunit methyltransferase G
INP51_RS16015	COG0445	tRNA wobble uridine modification
INP51_RS16020	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
INP51_RS16025	COG1847	R3H domain protein
INP51_RS16030	COG0706	membrane insertase activity
INP51_RS16035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
INP51_RS16040	COG0594	ribonuclease P activity
INP51_RS16045	COG0230	Belongs to the bacterial ribosomal protein bL34 family