locus-tag	class	description
EYS05_RS00005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EYS05_RS00010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EYS05_RS00015	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EYS05_RS00040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EYS05_RS00045	COG0167	dihydroorotate dehydrogenase activity
EYS05_RS00050	COG0543	2 iron, 2 sulfur cluster binding
EYS05_RS00055	COG0284	orotidine-5'-phosphate decarboxylase activity
EYS05_RS00065	COG1278	Cold shock
EYS05_RS00085	COG0745	RESPONSE REGULATOR receiver
EYS05_RS00110	COG0546	phosphoglycolate phosphatase activity
EYS05_RS00120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYS05_RS00140	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYS05_RS00150	COG0215	cysteine-tRNA ligase activity
EYS05_RS00155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EYS05_RS00165	COG2205	protein histidine kinase activity
EYS05_RS00165	COG0784	Response regulator, receiver
EYS05_RS00180	COG3437	response regulator, receiver
EYS05_RS00195	COG0251	oxidation-reduction process
EYS05_RS00205	COG1199	ATP-dependent helicase activity
EYS05_RS00215	COG0527	aspartate kinase activity
EYS05_RS00225	COG1720	tRNA m6t6A37 methyltransferase activity
EYS05_RS00230	COG3706	GGDEF domain
EYS05_RS00240	COG1349	DNA-binding transcription factor activity
EYS05_RS00245	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS05_RS00245	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS05_RS00250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS05_RS00250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS05_RS00250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EYS05_RS00255	COG1105	Belongs to the carbohydrate kinase PfkB family
EYS05_RS00265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EYS05_RS00285	COG2246	polysaccharide biosynthetic process
EYS05_RS00295	COG0574	Belongs to the PEP-utilizing enzyme family
EYS05_RS00295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EYS05_RS00310	COG0395	ABC-type sugar transport system, permease component
EYS05_RS00315	COG1175	transmembrane transport
EYS05_RS00320	COG1653	transport
EYS05_RS00330	COG0423	glycine-tRNA ligase activity
EYS05_RS00335	COG1381	Involved in DNA repair and RecF pathway recombination
EYS05_RS00340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EYS05_RS00360	COG1523	belongs to the glycosyl hydrolase 13 family
EYS05_RS00365	COG0708	Exodeoxyribonuclease III
EYS05_RS00370	COG3906	Belongs to the UPF0473 family
EYS05_RS00375	COG0756	dUTP diphosphatase activity
EYS05_RS00385	COG1185	polyribonucleotide nucleotidyltransferase activity
EYS05_RS00390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EYS05_RS00395	COG0196	riboflavin kinase activity
EYS05_RS00400	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EYS05_RS00410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EYS05_RS00415	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EYS05_RS00430	COG0195	Participates in both transcription termination and antitermination
EYS05_RS00435	COG0779	Required for maturation of 30S ribosomal subunits
EYS05_RS00450	COG1132	(ABC) transporter
EYS05_RS00455	COG4988	ABC transporter
EYS05_RS00460	COG2832	Protein of unknown function (DUF454)
EYS05_RS00465	COG1120	ATPase activity
EYS05_RS00500	COG1429	ligase activity, forming nitrogen-metal bonds
EYS05_RS00545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYS05_RS00550	COG0187	DNA topoisomerase II activity
EYS05_RS00560	COG2199	diguanylate cyclase activity
EYS05_RS00570	COG2333	competence protein COMEC
EYS05_RS00570	COG0658	competence protein
EYS05_RS00575	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EYS05_RS00590	COG1605	Chorismate mutase
EYS05_RS00590	COG0077	Prephenate dehydratase
EYS05_RS00595	COG0285	dihydrofolate synthase activity
EYS05_RS00605	COG0540	Belongs to the ATCase OTCase family
EYS05_RS00610	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EYS05_RS00620	COG0733	neurotransmitter:sodium symporter activity
EYS05_RS00625	COG0709	Synthesizes selenophosphate from selenide and ATP
EYS05_RS00640	COG2384	SAM-dependent methyltransferase
EYS05_RS00645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EYS05_RS00650	COG0358	DNA primase activity
EYS05_RS00655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EYS05_RS00675	COG1373	ATPase (AAA superfamily
EYS05_RS00690	COG0436	Aminotransferase
EYS05_RS00700	COG0154	amidase activity
EYS05_RS00705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EYS05_RS00710	COG0017	Asparaginyl-tRNA synthetase
EYS05_RS00725	COG0493	'glutamate synthase
EYS05_RS00730	COG0067	glutamate synthase
EYS05_RS00730	COG0069	glutamate synthase activity
EYS05_RS00730	COG0070	glutamate synthase
EYS05_RS00735	COG0504	CTP synthase activity
EYS05_RS00745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYS05_RS00755	COG0004	ammonium transporteR
EYS05_RS00760	COG2860	membrane
EYS05_RS00765	COG1827	regulation of RNA biosynthetic process
EYS05_RS00775	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EYS05_RS00780	COG1082	Xylose isomerase domain protein TIM barrel
EYS05_RS00795	COG0673	inositol 2-dehydrogenase activity
EYS05_RS00820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYS05_RS00825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS05_RS00825	COG0551	DNA topoisomerase type I activity
EYS05_RS00830	COG2116	formate transmembrane transporter activity
EYS05_RS00845	COG0165	Argininosuccinate lyase
EYS05_RS00855	COG1116	anion transmembrane transporter activity
EYS05_RS00860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EYS05_RS00865	COG3300	MHYT domain
EYS05_RS00865	COG5001	Diguanylate cyclase
EYS05_RS00870	COG0745	RESPONSE REGULATOR receiver
EYS05_RS00880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYS05_RS00885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYS05_RS00900	COG0789	Transcriptional regulator
EYS05_RS00900	COG4978	Transcriptional regulator
EYS05_RS00910	COG1088	dTDP-glucose 4,6-dehydratase activity
EYS05_RS00915	COG1091	dTDP-4-dehydrorhamnose reductase activity
EYS05_RS00920	COG1316	TRANSCRIPTIONal
EYS05_RS00925	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYS05_RS00930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYS05_RS00980	COG5039	Polysaccharide pyruvyl transferase
EYS05_RS00985	COG1216	Glycosyl transferase, family 2
EYS05_RS00990	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS01000	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS05_RS01025	COG4464	protein tyrosine phosphatase activity
EYS05_RS01035	COG0646	methionine synthase
EYS05_RS01035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYS05_RS01050	COG1177	transmembrane transport
EYS05_RS01065	COG1177	transmembrane transport
EYS05_RS01070	COG1176	ABC-type spermidine putrescine transport system, permease component I
EYS05_RS01075	COG3842	ATPase activity
EYS05_RS01085	COG0561	phosphatase activity
EYS05_RS01110	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EYS05_RS01125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EYS05_RS01130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EYS05_RS01135	COG0028	Belongs to the TPP enzyme family
EYS05_RS01155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYS05_RS01170	COG1862	Preprotein translocase
EYS05_RS01175	COG0343	queuine tRNA-ribosyltransferase activity
EYS05_RS01185	COG3546	catalase activity
EYS05_RS01200	COG0569	domain protein
EYS05_RS01220	COG2205	protein histidine kinase activity
EYS05_RS01230	COG0698	ribose 5-phosphate isomerase
EYS05_RS01235	COG0009	L-threonylcarbamoyladenylate synthase
EYS05_RS01250	COG1216	Glycosyl transferase, family 2
EYS05_RS01260	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS05_RS01275	COG4862	establishment of competence for transformation
EYS05_RS01285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EYS05_RS01295	COG0305	Participates in initiation and elongation during chromosome replication
EYS05_RS01300	COG0359	binds to the 23S rRNA
EYS05_RS01310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EYS05_RS01315	COG0629	single-stranded DNA binding
EYS05_RS01320	COG0360	Binds together with S18 to 16S ribosomal RNA
EYS05_RS01330	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EYS05_RS01335	COG4509	Sortase family
EYS05_RS01340	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EYS05_RS01365	COG0640	Transcriptional regulator
EYS05_RS01375	COG0205	6-phosphofructokinase activity
EYS05_RS01380	COG1028	Short-chain dehydrogenase reductase Sdr
EYS05_RS01380	COG3347	Dehydrogenase
EYS05_RS01410	COG1983	PspC domain protein
EYS05_RS01430	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYS05_RS01430	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EYS05_RS01435	COG1074	ATP-dependent DNA helicase activity
EYS05_RS01440	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EYS05_RS01455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EYS05_RS01460	COG2226	methyltransferase
EYS05_RS01475	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EYS05_RS01480	COG0395	ABC-type sugar transport system, permease component
EYS05_RS01485	COG1175	transmembrane transport
EYS05_RS01490	COG1653	transport
EYS05_RS01500	COG3279	Response regulator of the LytR AlgR family
EYS05_RS01505	COG3973	AAA domain
EYS05_RS01515	COG1501	Belongs to the glycosyl hydrolase 31 family
EYS05_RS01520	COG4977	sequence-specific DNA binding
EYS05_RS01540	COG1132	(ABC) transporter
EYS05_RS01560	COG0542	response to heat
EYS05_RS01585	COG1725	Transcriptional regulator
EYS05_RS01590	COG1131	(ABC) transporter
EYS05_RS01645	COG4804	nuclease activity
EYS05_RS01730	COG0741	lytic transglycosylase activity
EYS05_RS01730	COG0791	NLP P60 protein
EYS05_RS01790	COG2946	Replication initiation factor
EYS05_RS01795	COG1674	ftsk spoiiie
EYS05_RS01830	COG0784	Response regulator, receiver
EYS05_RS01830	COG5002	protein histidine kinase activity
EYS05_RS01830	COG2198	Histidine kinase
EYS05_RS01835	COG0784	Response regulator, receiver
EYS05_RS01835	COG2205	protein histidine kinase activity
EYS05_RS01845	COG0784	Response regulator, receiver
EYS05_RS01845	COG2205	protein histidine kinase activity
EYS05_RS01850	COG0784	Response regulator, receiver
EYS05_RS01850	COG2205	protein histidine kinase activity
EYS05_RS01880	COG0745	RESPONSE REGULATOR receiver
EYS05_RS01885	COG2205	protein histidine kinase activity
EYS05_RS01890	COG0569	domain protein
EYS05_RS01895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYS05_RS01900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYS05_RS01905	COG1268	BioY protein
EYS05_RS01935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYS05_RS01955	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EYS05_RS01960	COG0733	neurotransmitter:sodium symporter activity
EYS05_RS01970	COG3901	Regulator of nitric oxide reductase transcription
EYS05_RS01970	COG0348	domain, Protein
EYS05_RS01985	COG0745	RESPONSE REGULATOR receiver
EYS05_RS01990	COG5002	protein histidine kinase activity
EYS05_RS02010	COG1131	(ABC) transporter
EYS05_RS02020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYS05_RS02035	COG0765	amino acid transport
EYS05_RS02045	COG2508	Transcriptional regulator
EYS05_RS02050	COG2223	nitrite transmembrane transporter activity
EYS05_RS02065	COG0583	DNA-binding transcription factor activity
EYS05_RS02070	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EYS05_RS02080	COG1760	l-serine dehydratase
EYS05_RS02100	COG0058	SHG alpha-glucan phosphorylase activity
EYS05_RS02105	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS02105	COG2207	Transcriptional regulator
EYS05_RS02125	COG1454	alcohol dehydrogenase
EYS05_RS02130	COG1012	belongs to the aldehyde dehydrogenase family
EYS05_RS02135	COG1472	Belongs to the glycosyl hydrolase 3 family
EYS05_RS02140	COG0159	tryptophan synthase activity
EYS05_RS02145	COG0133	tryptophan synthase activity
EYS05_RS02150	COG0135	phosphoribosylanthranilate isomerase activity
EYS05_RS02155	COG0134	indole-3-glycerol-phosphate synthase activity
EYS05_RS02160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYS05_RS02165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EYS05_RS02165	COG0512	Glutamine amidotransferase of anthranilate synthase
EYS05_RS02180	COG2357	RelA SpoT domain protein
EYS05_RS02195	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS02200	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS02205	COG1129	ABC transporter
EYS05_RS02210	COG0745	RESPONSE REGULATOR receiver
EYS05_RS02215	COG2972	Histidine kinase
EYS05_RS02230	COG1070	Carbohydrate kinase
EYS05_RS02240	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS02245	COG1129	ABC transporter
EYS05_RS02250	COG4214	carbohydrate transport
EYS05_RS02260	COG2972	Histidine kinase
EYS05_RS02265	COG2207	Transcriptional regulator
EYS05_RS02265	COG4753	response regulator
EYS05_RS02270	COG0656	L-ascorbic acid biosynthetic process
EYS05_RS02275	COG1105	Belongs to the carbohydrate kinase PfkB family
EYS05_RS02280	COG1063	alcohol dehydrogenase
EYS05_RS02290	COG1609	Transcriptional regulator
EYS05_RS02300	COG4154	Belongs to the RbsD FucU family
EYS05_RS02315	COG0562	UDP-galactopyranose mutase
EYS05_RS02325	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EYS05_RS02365	COG0562	UDP-galactopyranose mutase
EYS05_RS02370	COG3594	Acyltransferase
EYS05_RS02395	COG0438	transferase activity, transferring glycosyl groups
EYS05_RS02400	COG3475	LICD family
EYS05_RS02410	COG1216	Glycosyl transferase, family 2
EYS05_RS02425	COG0582	viral genome integration into host DNA
EYS05_RS02430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EYS05_RS02440	COG5002	protein histidine kinase activity
EYS05_RS02450	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYS05_RS02470	COG4667	esterase of the alpha-beta hydrolase superfamily
EYS05_RS02475	COG0488	(ABC) transporter
EYS05_RS02485	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
EYS05_RS02490	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS05_RS02500	COG1132	(ABC) transporter
EYS05_RS02505	COG2375	cellular response to nickel ion
EYS05_RS02505	COG1132	(ABC) transporter
EYS05_RS02540	COG1131	(ABC) transporter
EYS05_RS02580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EYS05_RS02590	COG0101	tRNA pseudouridine synthase activity
EYS05_RS02595	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EYS05_RS02600	COG1122	ATPase activity
EYS05_RS02605	COG1122	ATPase activity
EYS05_RS02610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EYS05_RS02615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYS05_RS02620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYS05_RS02630	COG0544	peptidyl-prolyl cis-trans isomerase activity
EYS05_RS02645	COG2954	triphosphatase activity
EYS05_RS02655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EYS05_RS02665	COG1609	Transcriptional regulator
EYS05_RS02675	COG0395	ABC-type sugar transport system, permease component
EYS05_RS02680	COG1175	transmembrane transport
EYS05_RS02715	COG3620	sequence-specific DNA binding
EYS05_RS02725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYS05_RS02730	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EYS05_RS02735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EYS05_RS02745	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS02745	COG4977	sequence-specific DNA binding
EYS05_RS02750	COG2814	Major facilitator Superfamily
EYS05_RS02780	COG3842	ATPase activity
EYS05_RS02785	COG3835	regulator
EYS05_RS02795	COG4149	molybdate abc transporter
EYS05_RS02800	COG0725	ABC transporter, periplasmic molybdate-binding protein
EYS05_RS02805	COG3585	molybdate ion transport
EYS05_RS02810	COG1910	domain protein
EYS05_RS02825	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS02825	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS05_RS02830	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS05_RS02830	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS02835	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS05_RS02835	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS02875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EYS05_RS02880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS05_RS02890	COG1316	TRANSCRIPTIONal
EYS05_RS02895	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EYS05_RS02900	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS02905	COG0438	transferase activity, transferring glycosyl groups
EYS05_RS02905	COG1216	Glycosyl transferase, family 2
EYS05_RS02920	COG1216	Glycosyl transferase, family 2
EYS05_RS02920	COG0438	transferase activity, transferring glycosyl groups
EYS05_RS02935	COG1682	transport, permease protein
EYS05_RS02945	COG1686	Belongs to the peptidase S11 family
EYS05_RS02950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EYS05_RS02965	COG0463	Glycosyl transferase, family 2
EYS05_RS02970	COG2076	Multidrug Resistance protein
EYS05_RS02980	COG3757	hydrolase, family 25
EYS05_RS02990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS05_RS03000	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EYS05_RS03020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYS05_RS03035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYS05_RS03045	COG0481	GTPase activity
EYS05_RS03055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EYS05_RS03070	COG1466	dna polymerase III delta subunit
EYS05_RS03085	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EYS05_RS03095	COG0584	glycerophosphoryl diester phosphodiesterase
EYS05_RS03105	COG0446	pyridine nucleotide-disulphide oxidoreductase
EYS05_RS03110	COG0579	oxidoreductase
EYS05_RS03115	COG1285	pathogenesis
EYS05_RS03120	COG1653	transport
EYS05_RS03150	COG1136	(ABC) transporter
EYS05_RS03175	COG5002	protein histidine kinase activity
EYS05_RS03205	COG0745	RESPONSE REGULATOR receiver
EYS05_RS03210	COG2205	protein histidine kinase activity
EYS05_RS03220	COG0741	lytic transglycosylase activity
EYS05_RS03220	COG0791	NLP P60 protein
EYS05_RS03285	COG2946	Replication initiation factor
EYS05_RS03295	COG1674	ftsk spoiiie
EYS05_RS03325	COG0395	ABC-type sugar transport system, permease component
EYS05_RS03330	COG1175	transmembrane transport
EYS05_RS03350	COG1070	Carbohydrate kinase
EYS05_RS03370	COG0385	Bile acid
EYS05_RS03375	COG0463	Glycosyl transferase, family 2
EYS05_RS03385	COG0038	chloride channel
EYS05_RS03430	COG2205	protein histidine kinase activity
EYS05_RS03430	COG2770	Histidine kinase
EYS05_RS03435	COG0745	RESPONSE REGULATOR receiver
EYS05_RS03440	COG1288	antiporter activity
EYS05_RS03445	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EYS05_RS03465	COG0561	phosphatase activity
EYS05_RS03495	COG5001	Diguanylate cyclase
EYS05_RS03505	COG0577	efflux transmembrane transporter activity
EYS05_RS03515	COG1136	(ABC) transporter
EYS05_RS03515	COG0577	efflux transmembrane transporter activity
EYS05_RS03520	COG1362	aminopeptidase activity
EYS05_RS03540	COG1309	transcriptional regulator
EYS05_RS03545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EYS05_RS03550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYS05_RS03645	COG3958	Transketolase
EYS05_RS03660	COG1609	Transcriptional regulator
EYS05_RS03665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EYS05_RS03670	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EYS05_RS03675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYS05_RS03680	COG0205	6-phosphofructokinase activity
EYS05_RS03695	COG0590	tRNA wobble adenosine to inosine editing
EYS05_RS03705	COG1940	carbohydrate kinase activity
EYS05_RS03715	COG2211	Major facilitator Superfamily
EYS05_RS03750	COG1268	BioY protein
EYS05_RS03770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYS05_RS03775	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EYS05_RS03790	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYS05_RS03795	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYS05_RS03805	COG0420	3'-5' exonuclease activity
EYS05_RS03810	COG0017	Asparaginyl-tRNA synthetase
EYS05_RS03840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EYS05_RS03850	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EYS05_RS03865	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EYS05_RS03875	COG0537	adenosine 5'-monophosphoramidase activity
EYS05_RS03880	COG3852	Histidine kinase
EYS05_RS03975	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYS05_RS03980	COG1595	DNA-templated transcription, initiation
EYS05_RS03995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EYS05_RS04000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EYS05_RS04005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EYS05_RS04010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EYS05_RS04015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYS05_RS04020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EYS05_RS04025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYS05_RS04030	COG0356	it plays a direct role in the translocation of protons across the membrane
EYS05_RS04065	COG1379	DNA repair
EYS05_RS04080	COG4608	Belongs to the ABC transporter superfamily
EYS05_RS04090	COG4166	transmembrane transport
EYS05_RS04095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS05_RS04100	COG0601	transmembrane transport
EYS05_RS04115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS05_RS04120	COG0601	transmembrane transport
EYS05_RS04125	COG0583	DNA-binding transcription factor activity
EYS05_RS04130	COG2226	methyltransferase
EYS05_RS04135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EYS05_RS04150	COG0657	acetylesterase activity
EYS05_RS04165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYS05_RS04175	COG1846	Transcriptional regulator
EYS05_RS04185	COG0439	Biotin carboxylase
EYS05_RS04190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EYS05_RS04195	COG0511	ligase activity, forming carbon-carbon bonds
EYS05_RS04200	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EYS05_RS04210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EYS05_RS04220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYS05_RS04245	COG0426	domain, Protein
EYS05_RS04250	COG1929	Belongs to the glycerate kinase type-1 family
EYS05_RS04255	COG3835	regulator
EYS05_RS04260	COG1254	Belongs to the acylphosphatase family
EYS05_RS04270	COG0583	DNA-binding transcription factor activity
EYS05_RS04280	COG0484	heat shock protein binding
EYS05_RS04300	COG2207	Transcriptional regulator
EYS05_RS04315	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS05_RS04345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EYS05_RS04360	COG0523	cobalamin synthesis protein
EYS05_RS04375	COG0523	cobalamin synthesis protein
EYS05_RS04390	COG1115	amino acid carrier protein
EYS05_RS04400	COG0778	Nitroreductase
EYS05_RS04405	COG0697	spore germination
EYS05_RS04415	COG0742	ribosomal rna small subunit methyltransferase
EYS05_RS04420	COG0737	Belongs to the 5'-nucleotidase family
EYS05_RS04420	COG1525	nuclease
EYS05_RS04420	COG4085	toxin activity
EYS05_RS04440	COG2972	Histidine kinase
EYS05_RS04445	COG4753	response regulator
EYS05_RS04445	COG2207	Transcriptional regulator
EYS05_RS04450	COG2211	Major facilitator Superfamily
EYS05_RS04455	COG0628	permease
EYS05_RS04460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYS05_RS04470	COG1342	Belongs to the UPF0251 family
EYS05_RS04510	COG0488	(ABC) transporter
EYS05_RS04535	COG0582	viral genome integration into host DNA
EYS05_RS04550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EYS05_RS04550	COG0519	Catalyzes the synthesis of GMP from XMP
EYS05_RS04555	COG1115	amino acid carrier protein
EYS05_RS04585	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EYS05_RS04620	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EYS05_RS04630	COG1394	ATPase activity, coupled to movement of substances
EYS05_RS04640	COG0363	glucosamine-6-phosphate deaminase activity
EYS05_RS04650	COG0395	ABC-type sugar transport system, permease component
EYS05_RS04655	COG1175	transmembrane transport
EYS05_RS04660	COG1653	transport
EYS05_RS04670	COG1609	Transcriptional regulator
EYS05_RS04675	COG1609	Transcriptional regulator
EYS05_RS04690	COG1349	DNA-binding transcription factor activity
EYS05_RS04695	COG2234	aminopeptidase activity
EYS05_RS04700	COG0791	NLP P60 protein
EYS05_RS04710	COG0561	phosphatase activity
EYS05_RS04720	COG3716	PTS system mannose fructose sorbose family IID component
EYS05_RS04725	COG3715	PTS system
EYS05_RS04740	COG0492	ferredoxin-NADP+ reductase activity
EYS05_RS04755	COG0824	Thioesterase
EYS05_RS04765	COG2843	Capsule synthesis protein
EYS05_RS04775	COG0726	polysaccharide deacetylase
EYS05_RS04805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EYS05_RS04820	COG0697	spore germination
EYS05_RS04825	COG1802	Transcriptional regulator
EYS05_RS04830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EYS05_RS04850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYS05_RS04855	COG1882	Formate acetyltransferase
EYS05_RS04860	COG1126	abc transporter atp-binding protein
EYS05_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS05_RS04870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS05_RS04880	COG2188	Transcriptional regulator
EYS05_RS04885	COG1686	Belongs to the peptidase S11 family
EYS05_RS04930	COG1131	(ABC) transporter
EYS05_RS04955	COG0741	lytic transglycosylase activity
EYS05_RS04955	COG0791	NLP P60 protein
EYS05_RS05020	COG2946	Replication initiation factor
EYS05_RS05025	COG1674	ftsk spoiiie
EYS05_RS05030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EYS05_RS05055	COG0081	regulation of translation
EYS05_RS05065	COG0250	Participates in transcription elongation, termination and antitermination
EYS05_RS05075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EYS05_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
EYS05_RS05085	COG0028	Belongs to the TPP enzyme family
EYS05_RS05095	COG3475	LICD family
EYS05_RS05105	COG3594	Acyltransferase
EYS05_RS05130	COG1175	transmembrane transport
EYS05_RS05135	COG3842	ATPase activity
EYS05_RS05190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EYS05_RS05195	COG0602	queuosine metabolic process
EYS05_RS05200	COG0720	synthase
EYS05_RS05205	COG0653	protein targeting
EYS05_RS05225	COG4209	transmembrane transport
EYS05_RS05230	COG1609	Transcriptional regulator
EYS05_RS05240	COG0426	domain, Protein
EYS05_RS05245	COG0534	Mate efflux family protein
EYS05_RS05275	COG1609	Transcriptional regulator
EYS05_RS05295	COG1047	Peptidyl-prolyl cis-trans
EYS05_RS05310	COG2264	protein methyltransferase activity
EYS05_RS05320	COG4608	Belongs to the ABC transporter superfamily
EYS05_RS05325	COG0444	Belongs to the ABC transporter superfamily
EYS05_RS05330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS05_RS05335	COG0601	transmembrane transport
EYS05_RS05340	COG0534	Mate efflux family protein
EYS05_RS05380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EYS05_RS05380	COG1199	ATP-dependent helicase activity
EYS05_RS05410	COG1132	(ABC) transporter
EYS05_RS05415	COG1132	(ABC) transporter
EYS05_RS05420	COG1129	ABC transporter
EYS05_RS05455	COG1132	(ABC) transporter
EYS05_RS05460	COG2375	cellular response to nickel ion
EYS05_RS05460	COG1132	(ABC) transporter
EYS05_RS05470	COG1129	ABC transporter
EYS05_RS05490	COG0791	NLP P60 protein
EYS05_RS05490	COG0741	lytic transglycosylase activity
EYS05_RS05590	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYS05_RS05595	COG4509	Sortase family
EYS05_RS05665	COG2188	Transcriptional regulator
EYS05_RS05675	COG1309	transcriptional regulator
EYS05_RS05680	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EYS05_RS05700	COG0577	efflux transmembrane transporter activity
EYS05_RS05700	COG1136	(ABC) transporter
EYS05_RS05785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYS05_RS05800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS05_RS05800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS05_RS05835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS05_RS05840	COG1486	melibiose metabolic process
EYS05_RS05845	COG3681	Belongs to the UPF0597 family
EYS05_RS05850	COG1473	amidohydrolase
EYS05_RS05855	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EYS05_RS05860	COG0395	ABC-type sugar transport system, permease component
EYS05_RS05870	COG1653	transport
EYS05_RS05885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS05_RS05885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS05_RS05890	COG0582	viral genome integration into host DNA
EYS05_RS05935	COG3279	Response regulator of the LytR AlgR family
EYS05_RS05960	COG1131	(ABC) transporter
EYS05_RS05970	COG0312	modulator of DNA gyrase
EYS05_RS06000	COG1396	sequence-specific DNA binding
EYS05_RS06025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS05_RS06025	COG0551	DNA topoisomerase type I activity
EYS05_RS06040	COG0791	NLP P60 protein
EYS05_RS06040	COG0741	lytic transglycosylase activity
EYS05_RS06210	COG1192	Involved in chromosome partitioning
EYS05_RS06220	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EYS05_RS06225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EYS05_RS06235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EYS05_RS06245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EYS05_RS06245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EYS05_RS06250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EYS05_RS06265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EYS05_RS06270	COG0569	domain protein
EYS05_RS06275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EYS05_RS06290	COG2996	Protein conserved in bacteria
EYS05_RS06295	COG1757	Na H antiporter
EYS05_RS06320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EYS05_RS06325	COG1876	peptidase activity
EYS05_RS06330	COG2002	toxin-antitoxin pair type II binding
EYS05_RS06365	COG1621	beta-fructofuranosidase activity
EYS05_RS06375	COG1609	Transcriptional regulator
EYS05_RS06380	COG0739	heme binding
EYS05_RS06465	COG2895	sulfate adenylyltransferase (ATP) activity
EYS05_RS06470	COG0175	sulfate reduction
EYS05_RS06490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EYS05_RS06520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYS05_RS06530	COG2022	thiamine diphosphate biosynthetic process
EYS05_RS06555	COG0833	amino acid
EYS05_RS06570	COG3344	reverse transcriptase
EYS05_RS06585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EYS05_RS06590	COG4208	sulfate ABC transporter
EYS05_RS06600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EYS05_RS06605	COG1609	Transcriptional regulator
EYS05_RS06635	COG1175	transmembrane transport
EYS05_RS06655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EYS05_RS06660	COG0187	DNA topoisomerase II activity
EYS05_RS06670	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EYS05_RS06675	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EYS05_RS06680	COG1774	PSP1 C-terminal conserved region
EYS05_RS06685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EYS05_RS06690	COG0194	GDP metabolic process
EYS05_RS06695	COG1982	Orn Lys Arg decarboxylase major
EYS05_RS06700	COG0745	RESPONSE REGULATOR receiver
EYS05_RS06705	COG5002	protein histidine kinase activity
EYS05_RS06710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EYS05_RS06755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYS05_RS06760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYS05_RS06765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EYS05_RS06785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EYS05_RS06800	COG2501	S4 domain
EYS05_RS06805	COG0592	DNA-directed DNA polymerase activity
EYS05_RS06810	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EYS05_RS06825	COG0594	ribonuclease P activity
EYS05_RS06830	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EYS05_RS06840	COG1847	R3H domain protein
EYS05_RS06850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EYS05_RS06855	COG0445	tRNA wobble uridine modification
EYS05_RS06860	COG0357	Ribosomal RNA small subunit methyltransferase G
EYS05_RS06865	COG1131	(ABC) transporter
EYS05_RS06885	COG1511	domain protein
EYS05_RS06905	COG1192	Involved in chromosome partitioning
EYS05_RS06910	COG1475	DNA binding
EYS05_RS06920	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EYS05_RS06965	COG0454	-acetyltransferase
EYS05_RS06970	COG1373	ATPase (AAA superfamily
EYS05_RS06985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS05_RS06990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS05_RS07000	COG5002	protein histidine kinase activity
EYS05_RS07020	COG0583	DNA-binding transcription factor activity
EYS05_RS07030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYS05_RS07050	COG1733	regulation of RNA biosynthetic process
EYS05_RS07080	COG3340	Belongs to the peptidase S51 family
EYS05_RS07095	COG0519	Catalyzes the synthesis of GMP from XMP
EYS05_RS07170	COG0242	peptide deformylase activity
EYS05_RS07175	COG0346	lactoylglutathione lyase activity
EYS05_RS07180	COG1671	Belongs to the UPF0178 family
EYS05_RS07190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYS05_RS07200	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS07200	COG2207	Transcriptional regulator
EYS05_RS07305	COG0456	acetyltransferase
EYS05_RS07335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EYS05_RS07345	COG0534	Mate efflux family protein
EYS05_RS07350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYS05_RS07365	COG2207	Transcriptional regulator
EYS05_RS07370	COG1151	hydroxylamine reductase activity
EYS05_RS07405	COG5001	Diguanylate cyclase
EYS05_RS07440	COG1012	belongs to the aldehyde dehydrogenase family
EYS05_RS07445	COG1349	DNA-binding transcription factor activity
EYS05_RS07455	COG0803	Belongs to the bacterial solute-binding protein 9 family
EYS05_RS07455	COG3443	Belongs to the bacterial solute-binding protein 9 family
EYS05_RS07460	COG1121	(ABC) transporter
EYS05_RS07465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EYS05_RS07470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EYS05_RS07475	COG1609	Transcriptional regulator
EYS05_RS07485	COG3959	Transketolase, thiamine diphosphate binding domain
EYS05_RS07490	COG3958	Transketolase
EYS05_RS07495	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EYS05_RS07505	COG1611	Belongs to the LOG family
EYS05_RS07510	COG3250	beta-galactosidase activity
EYS05_RS07515	COG1115	amino acid carrier protein
EYS05_RS07530	COG1874	Beta-galactosidase
EYS05_RS07550	COG1263	PTS System
EYS05_RS07550	COG2190	(PTS) system
EYS05_RS07550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS05_RS07555	COG1263	PTS System
EYS05_RS07555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS05_RS07555	COG2190	(PTS) system
EYS05_RS07575	COG0071	Belongs to the small heat shock protein (HSP20) family
EYS05_RS07585	COG2176	DNA-directed DNA polymerase activity
EYS05_RS07590	COG1686	Belongs to the peptidase S11 family
EYS05_RS07595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EYS05_RS07600	COG0058	SHG alpha-glucan phosphorylase activity
EYS05_RS07630	COG1773	rubredoxin
EYS05_RS07630	COG1592	Rubrerythrin
EYS05_RS07670	COG0315	cyclic pyranopterin monophosphate synthase activity
EYS05_RS07680	COG0521	Mo-molybdopterin cofactor biosynthetic process
EYS05_RS07685	COG0084	hydrolase, TatD family'
EYS05_RS07700	COG1120	ATPase activity
EYS05_RS07705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS05_RS07720	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYS05_RS07720	COG3608	succinylglutamate desuccinylase aspartoacylase
EYS05_RS07730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EYS05_RS07765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EYS05_RS07770	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EYS05_RS07805	COG2119	membrane
EYS05_RS07810	COG1609	Transcriptional regulator
EYS05_RS07830	COG0745	RESPONSE REGULATOR receiver
EYS05_RS07850	COG0358	DNA primase activity
EYS05_RS07910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EYS05_RS07915	COG0049	tRNA binding
EYS05_RS07920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYS05_RS07940	COG0745	RESPONSE REGULATOR receiver
EYS05_RS07945	COG2205	protein histidine kinase activity
EYS05_RS07950	COG1136	(ABC) transporter
EYS05_RS07990	COG0358	DNA primase activity
EYS05_RS08035	COG2199	diguanylate cyclase activity
EYS05_RS08045	COG1595	DNA-templated transcription, initiation
EYS05_RS08055	COG1393	Belongs to the ArsC family
EYS05_RS08060	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS05_RS08065	COG2252	PERMEase
EYS05_RS08090	COG1175	transmembrane transport
EYS05_RS08095	COG0395	ABC-type sugar transport system, permease component
EYS05_RS08100	COG1501	Belongs to the glycosyl hydrolase 31 family
EYS05_RS08135	COG0667	Aldo Keto reductase
EYS05_RS08150	COG0352	thiamine-phosphate diphosphorylase activity
EYS05_RS08160	COG1522	sequence-specific DNA binding
EYS05_RS08165	COG1027	Aspartate ammonia-lyase
EYS05_RS08170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EYS05_RS08175	COG0733	neurotransmitter:sodium symporter activity
EYS05_RS08180	COG3279	Response regulator of the LytR AlgR family
EYS05_RS08185	COG2972	Histidine kinase
EYS05_RS08190	COG1653	transport
EYS05_RS08195	COG1175	transmembrane transport
EYS05_RS08200	COG0395	ABC-type sugar transport system, permease component
EYS05_RS08205	COG3250	beta-galactosidase activity
EYS05_RS08215	COG2207	Transcriptional regulator
EYS05_RS08220	COG4753	response regulator
EYS05_RS08220	COG2207	Transcriptional regulator
EYS05_RS08230	COG0561	phosphatase activity
EYS05_RS08235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EYS05_RS08245	COG0222	ribosome binding
EYS05_RS08260	COG0085	RNA polymerase activity
EYS05_RS08265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EYS05_RS08270	COG0515	serine threonine protein kinase
EYS05_RS08300	COG1695	Transcriptional regulator
EYS05_RS08320	COG1959	2 iron, 2 sulfur cluster binding
EYS05_RS08330	COG0573	inorganic phosphate transmembrane transporter activity
EYS05_RS08335	COG0581	inorganic phosphate transmembrane transporter activity
EYS05_RS08340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EYS05_RS08345	COG0704	Plays a role in the regulation of phosphate uptake
EYS05_RS08350	COG5002	protein histidine kinase activity
EYS05_RS08355	COG4535	Mg2 and Co2 transporter CorC
EYS05_RS08390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYS05_RS08390	COG0116	Belongs to the methyltransferase superfamily
EYS05_RS08395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS05_RS08405	COG1181	Belongs to the D-alanine--D-alanine ligase family
EYS05_RS08410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EYS05_RS08420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYS05_RS08425	COG1737	Transcriptional regulator
EYS05_RS08435	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EYS05_RS08455	COG1269	ATP hydrolysis coupled proton transport
EYS05_RS08460	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EYS05_RS08475	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EYS05_RS08480	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
EYS05_RS08485	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
EYS05_RS08490	COG1394	ATPase activity, coupled to movement of substances
EYS05_RS08495	COG0671	phosphoesterase, PA-phosphatase related
EYS05_RS08500	COG0436	Aminotransferase
EYS05_RS08505	COG1012	belongs to the aldehyde dehydrogenase family
EYS05_RS08505	COG1454	alcohol dehydrogenase
EYS05_RS08510	COG1217	gtp-binding protein TYPA
EYS05_RS08525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EYS05_RS08530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EYS05_RS08560	COG0653	protein targeting
EYS05_RS08565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EYS05_RS08575	COG4492	Belongs to the UPF0735 family
EYS05_RS08580	COG0460	homoserine dehydrogenase
EYS05_RS08610	COG0348	domain, Protein
EYS05_RS08610	COG3901	Regulator of nitric oxide reductase transcription
EYS05_RS08615	COG1477	protein flavinylation
EYS05_RS08630	COG0039	L-malate dehydrogenase activity
EYS05_RS08635	COG2183	response to ionizing radiation
EYS05_RS08640	COG0668	transmembrane transport
EYS05_RS08645	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EYS05_RS08650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EYS05_RS08655	COG0385	Bile acid
EYS05_RS08660	COG2207	Transcriptional regulator
EYS05_RS08680	COG1175	transmembrane transport
EYS05_RS08690	COG2972	Histidine kinase
EYS05_RS08695	COG2207	Transcriptional regulator
EYS05_RS08695	COG4753	response regulator
EYS05_RS08705	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EYS05_RS08715	COG2816	NAD+ diphosphatase activity
EYS05_RS08725	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EYS05_RS08735	COG1063	alcohol dehydrogenase
EYS05_RS08740	COG2211	Major facilitator Superfamily
EYS05_RS08770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYS05_RS08825	COG1404	Belongs to the peptidase S8 family
EYS05_RS08850	COG1484	DNA-dependent DNA replication
EYS05_RS08880	COG1131	(ABC) transporter
EYS05_RS08895	COG1132	(ABC) transporter
EYS05_RS08925	COG1959	2 iron, 2 sulfur cluster binding
EYS05_RS08980	COG1472	Belongs to the glycosyl hydrolase 3 family
EYS05_RS08985	COG1472	Belongs to the glycosyl hydrolase 3 family
EYS05_RS09005	COG1959	2 iron, 2 sulfur cluster binding
EYS05_RS09045	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EYS05_RS09065	COG4656	Part of a membrane complex involved in electron transport
EYS05_RS09075	COG0646	methionine synthase
EYS05_RS09075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYS05_RS09080	COG0572	uridine kinase
EYS05_RS09085	COG1940	carbohydrate kinase activity
EYS05_RS09095	COG0246	Mannitol dehydrogenase
EYS05_RS09100	COG2610	gluconate transmembrane transporter activity
EYS05_RS09105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS05_RS09110	COG0346	lactoylglutathione lyase activity
EYS05_RS09125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS05_RS09140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
EYS05_RS09145	COG0281	malic enzyme
EYS05_RS09150	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EYS05_RS09185	COG1459	type II secretion system
EYS05_RS09210	COG0254	rRNA binding
EYS05_RS09215	COG3872	metal-dependent enzyme
EYS05_RS09220	COG2890	protein-(glutamine-N5) methyltransferase activity
EYS05_RS09225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EYS05_RS09235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYS05_RS09245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EYS05_RS09250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYS05_RS09250	COG1328	CTP reductase activity
EYS05_RS09270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EYS05_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EYS05_RS09280	COG0765	amino acid transport
EYS05_RS09285	COG1126	abc transporter atp-binding protein
EYS05_RS09295	COG2502	aspartate--ammonia ligase
EYS05_RS09305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EYS05_RS09305	COG1328	CTP reductase activity
EYS05_RS09310	COG0549	Belongs to the carbamate kinase family
EYS05_RS09325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EYS05_RS09340	COG2738	Putative neutral zinc metallopeptidase
EYS05_RS09345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EYS05_RS09345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYS05_RS09350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYS05_RS09355	COG0631	protein serine/threonine phosphatase activity
EYS05_RS09360	COG0515	serine threonine protein kinase
EYS05_RS09360	COG2815	serine threonine protein kinase
EYS05_RS09370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EYS05_RS09380	COG0012	GTP binding
EYS05_RS09385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EYS05_RS09395	COG3250	beta-galactosidase activity
EYS05_RS09400	COG2001	Belongs to the MraZ family
EYS05_RS09415	COG0768	penicillin binding
EYS05_RS09420	COG0768	penicillin binding
EYS05_RS09425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EYS05_RS09430	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EYS05_RS09435	COG0772	Belongs to the SEDS family
EYS05_RS09440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EYS05_RS09450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EYS05_RS09460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EYS05_RS09505	COG0726	polysaccharide deacetylase
EYS05_RS09510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EYS05_RS09520	COG1242	4 iron, 4 sulfur cluster binding
EYS05_RS09525	COG5578	integral membrane protein
EYS05_RS09530	COG4496	protein, YerC YecD
EYS05_RS09540	COG0210	DNA helicase
EYS05_RS09550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EYS05_RS09580	COG1846	Transcriptional regulator
EYS05_RS09580	COG1940	carbohydrate kinase activity
EYS05_RS09585	COG1063	alcohol dehydrogenase
EYS05_RS09595	COG2211	Major facilitator Superfamily
EYS05_RS09605	COG0440	acetolactate synthase activity
EYS05_RS09610	COG0028	Belongs to the TPP enzyme family
EYS05_RS09615	COG1253	flavin adenine dinucleotide binding
EYS05_RS09630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EYS05_RS09645	COG2207	Transcriptional regulator
EYS05_RS09665	COG1175	transmembrane transport
EYS05_RS09670	COG0395	ABC-type sugar transport system, permease component
EYS05_RS09680	COG2207	Transcriptional regulator
EYS05_RS09685	COG1486	melibiose metabolic process
EYS05_RS09690	COG1609	Transcriptional regulator
EYS05_RS09715	COG1234	tRNA 3'-trailer cleavage
EYS05_RS09720	COG1606	tRNA processing
EYS05_RS09725	COG4716	Myosin-crossreactive antigen
EYS05_RS09730	COG1309	transcriptional regulator
EYS05_RS09745	COG2207	Transcriptional regulator
EYS05_RS09750	COG4213	ABC transporter substrate-binding protein
EYS05_RS09755	COG4213	ABC transporter substrate-binding protein
EYS05_RS09765	COG1172	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS09780	COG1757	Na H antiporter
EYS05_RS09785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYS05_RS09790	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYS05_RS09800	COG1192	Involved in chromosome partitioning
EYS05_RS09810	COG1132	(ABC) transporter
EYS05_RS09815	COG2190	(PTS) system
EYS05_RS09815	COG1263	PTS System
EYS05_RS09815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EYS05_RS09845	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EYS05_RS09850	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EYS05_RS09865	COG0622	Phosphoesterase
EYS05_RS09870	COG0116	Belongs to the methyltransferase superfamily
EYS05_RS09875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EYS05_RS09880	COG0622	Phosphoesterase
EYS05_RS09895	COG2199	diguanylate cyclase activity
EYS05_RS09895	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EYS05_RS09945	COG1132	(ABC) transporter
EYS05_RS09950	COG1132	(ABC) transporter
EYS05_RS09970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EYS05_RS09975	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EYS05_RS09980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EYS05_RS09985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EYS05_RS10005	COG1918	ferrous iron import across plasma membrane
EYS05_RS10005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYS05_RS10025	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EYS05_RS10030	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EYS05_RS10040	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
EYS05_RS10055	COG0309	Hydrogenase expression formation protein (HypE)
EYS05_RS10065	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EYS05_RS10085	COG1555	photosystem II stabilization
EYS05_RS10085	COG1596	polysaccharide export
EYS05_RS10090	COG0745	RESPONSE REGULATOR receiver
EYS05_RS10105	COG2333	competence protein COMEC
EYS05_RS10105	COG0658	competence protein
EYS05_RS10110	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
EYS05_RS10130	COG4139	cobalamin transport
EYS05_RS10135	COG1120	ATPase activity
EYS05_RS10140	COG4086	secreted protein
EYS05_RS10145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EYS05_RS10160	COG0484	heat shock protein binding
EYS05_RS10165	COG1748	Saccharopine dehydrogenase
EYS05_RS10175	COG1388	LysM domain
EYS05_RS10175	COG0791	NLP P60 protein
EYS05_RS10175	COG3103	Sh3 type 3 domain protein
EYS05_RS10185	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYS05_RS10190	COG1882	Formate acetyltransferase
EYS05_RS10195	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EYS05_RS10205	COG1012	belongs to the aldehyde dehydrogenase family
EYS05_RS10210	COG1063	alcohol dehydrogenase
EYS05_RS10235	COG4869	propanediol catabolic process
EYS05_RS10240	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EYS05_RS10245	COG4656	Part of a membrane complex involved in electron transport
EYS05_RS10250	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EYS05_RS10275	COG0514	ATP-dependent DNA helicase (RecQ)
EYS05_RS10285	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EYS05_RS10305	COG0667	Aldo Keto reductase
EYS05_RS10310	COG0420	3'-5' exonuclease activity
EYS05_RS10315	COG0419	ATPase involved in DNA repair
EYS05_RS10320	COG4868	Belongs to the UPF0371 family
EYS05_RS10325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS05_RS10330	COG0322	excinuclease ABC activity
EYS05_RS10335	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EYS05_RS10340	COG1940	carbohydrate kinase activity
EYS05_RS10345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EYS05_RS10350	COG1739	Uncharacterized protein family UPF0029
EYS05_RS10355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYS05_RS10360	COG0802	atpase or kinase
EYS05_RS10365	COG1214	PFAM Peptidase M22, glycoprotease
EYS05_RS10370	COG0456	acetyltransferase
EYS05_RS10375	COG1234	tRNA 3'-trailer cleavage
EYS05_RS10385	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYS05_RS10455	COG0285	dihydrofolate synthase activity
EYS05_RS10465	COG1366	Belongs to the anti-sigma-factor antagonist family
EYS05_RS10475	COG1191	sigma factor activity
EYS05_RS10490	COG1091	dTDP-4-dehydrorhamnose reductase activity
EYS05_RS10495	COG1301	dicarboxylic acid transport
EYS05_RS10500	COG0583	DNA-binding transcription factor activity
EYS05_RS10525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EYS05_RS10540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EYS05_RS10545	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EYS05_RS10555	COG1481	regulation of sporulation
EYS05_RS10560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EYS05_RS10570	COG0051	transcription antitermination factor activity, RNA binding
EYS05_RS10575	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EYS05_RS10590	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EYS05_RS10600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EYS05_RS10610	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EYS05_RS10615	COG0255	Belongs to the universal ribosomal protein uL29 family
EYS05_RS10620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EYS05_RS10640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EYS05_RS10645	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EYS05_RS10650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EYS05_RS10660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EYS05_RS10670	COG0200	Binds to the 23S rRNA
EYS05_RS10690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EYS05_RS10695	COG0733	neurotransmitter:sodium symporter activity
EYS05_RS10700	COG2188	Transcriptional regulator
EYS05_RS10710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EYS05_RS10720	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EYS05_RS10725	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EYS05_RS10730	COG0202	RNA polymerase activity
EYS05_RS10735	COG0203	ribosomal protein L17
EYS05_RS10740	COG3279	Response regulator of the LytR AlgR family
EYS05_RS10755	COG3442	glutamine amidotransferase
EYS05_RS10770	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EYS05_RS10780	COG1937	Protein conserved in bacteria
EYS05_RS10790	COG0583	DNA-binding transcription factor activity
EYS05_RS10795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EYS05_RS10840	COG1297	OPT oligopeptide transporter protein
EYS05_RS10850	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EYS05_RS10855	COG2508	Transcriptional regulator
EYS05_RS10860	COG2884	Cell division ATP-binding protein ftsE
EYS05_RS10865	COG2177	Part of the ABC transporter FtsEX involved in
EYS05_RS10890	COG1183	phosphatidylcholine synthase activity
EYS05_RS10895	COG0688	phosphatidylethanolamine metabolic process
EYS05_RS10900	COG0745	RESPONSE REGULATOR receiver
EYS05_RS10905	COG5002	protein histidine kinase activity
EYS05_RS10910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EYS05_RS10915	COG0107	imidazoleglycerol-phosphate synthase activity
EYS05_RS10930	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYS05_RS10940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EYS05_RS10945	COG2137	regulation of response to DNA damage stimulus
EYS05_RS10950	COG1418	mRNA catabolic process
EYS05_RS10960	COG4974	Belongs to the 'phage' integrase family
EYS05_RS10965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EYS05_RS10975	COG1959	2 iron, 2 sulfur cluster binding
EYS05_RS10985	COG0822	iron-sulfur transferase activity
EYS05_RS10990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EYS05_RS10995	COG0366	Alpha amylase catalytic
EYS05_RS11015	COG0149	triose-phosphate isomerase activity
EYS05_RS11035	COG0460	homoserine dehydrogenase
EYS05_RS11040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EYS05_RS11095	COG1396	sequence-specific DNA binding
EYS05_RS11115	COG0534	Mate efflux family protein
EYS05_RS11130	COG0534	Mate efflux family protein
EYS05_RS11140	COG1489	DNA binding
EYS05_RS11145	COG1194	a g-specific adenine glycosylase
EYS05_RS11150	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS11160	COG1597	lipid kinase activity
EYS05_RS11165	COG0745	RESPONSE REGULATOR receiver
EYS05_RS11185	COG0583	DNA-binding transcription factor activity
EYS05_RS11190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYS05_RS11195	COG0583	DNA-binding transcription factor activity
EYS05_RS11225	COG0710	3-dehydroquinate dehydratase activity
EYS05_RS11230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYS05_RS11240	COG0494	nUDIX hydrolase
EYS05_RS11265	COG1115	amino acid carrier protein
EYS05_RS11270	COG1228	amidohydrolase
EYS05_RS11280	COG4977	sequence-specific DNA binding
EYS05_RS11325	COG2207	Transcriptional regulator
EYS05_RS11330	COG2972	Histidine kinase
EYS05_RS11330	COG0745	RESPONSE REGULATOR receiver
EYS05_RS11340	COG1175	transmembrane transport
EYS05_RS11360	COG1420	regulation of RNA biosynthetic process
EYS05_RS11365	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EYS05_RS11370	COG0443	Heat shock 70 kDa protein
EYS05_RS11375	COG0484	heat shock protein binding
EYS05_RS11380	COG2264	protein methyltransferase activity
EYS05_RS11385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EYS05_RS11390	COG1104	cysteine desulfurase activity
EYS05_RS11405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYS05_RS11410	COG4472	Bacterial protein of unknown function (DUF965)
EYS05_RS11420	COG3906	Belongs to the UPF0473 family
EYS05_RS11425	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EYS05_RS11440	COG4122	O-methyltransferase activity
EYS05_RS11445	COG0826	peptidase U32
EYS05_RS11485	COG0765	amino acid transport
EYS05_RS11490	COG1126	abc transporter atp-binding protein
EYS05_RS11520	COG0653	protein targeting
EYS05_RS11530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYS05_RS11535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EYS05_RS11545	COG1191	sigma factor activity
EYS05_RS11550	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS11550	COG2207	Transcriptional regulator
EYS05_RS11555	COG3250	beta-galactosidase activity
EYS05_RS11565	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EYS05_RS11570	COG0617	tRNA 3'-terminal CCA addition
EYS05_RS11580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EYS05_RS11585	COG0776	regulation of translation
EYS05_RS11590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EYS05_RS11610	COG0037	tRNA processing
EYS05_RS11620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS05_RS11630	COG0640	Transcriptional regulator
EYS05_RS11635	COG2217	Heavy metal translocating P-type atpase
EYS05_RS11655	COG0436	Aminotransferase
EYS05_RS11660	COG0583	DNA-binding transcription factor activity
EYS05_RS11665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EYS05_RS11670	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EYS05_RS11675	COG1984	allophanate hydrolase subunit 2
EYS05_RS11680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYS05_RS11710	COG2207	Transcriptional regulator
EYS05_RS11710	COG4753	response regulator
EYS05_RS11715	COG2972	Histidine kinase
EYS05_RS11720	COG1653	transport
EYS05_RS11755	COG1846	Transcriptional regulator
EYS05_RS11770	COG2207	Transcriptional regulator
EYS05_RS11770	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS11785	COG3507	Belongs to the glycosyl hydrolase 43 family
EYS05_RS11790	COG0534	Mate efflux family protein
EYS05_RS11795	COG0564	pseudouridine synthase activity
EYS05_RS11800	COG2197	response regulator
EYS05_RS11805	COG3851	Histidine kinase
EYS05_RS11810	COG1131	(ABC) transporter
EYS05_RS11835	COG0667	Aldo Keto reductase
EYS05_RS11910	COG2226	methyltransferase
EYS05_RS11925	COG0784	Response regulator, receiver
EYS05_RS11925	COG2198	Histidine kinase
EYS05_RS11925	COG2205	protein histidine kinase activity
EYS05_RS11960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYS05_RS11965	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EYS05_RS11985	COG1045	serine acetyltransferase
EYS05_RS12010	COG2155	Conserved Protein
EYS05_RS12045	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EYS05_RS12050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EYS05_RS12060	COG3853	Toxic anion resistance protein (TelA)
EYS05_RS12065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EYS05_RS12090	COG0606	chelatase, subunit chli
EYS05_RS12095	COG0758	DNA mediated transformation
EYS05_RS12100	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS05_RS12110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYS05_RS12115	COG0459	protein refolding
EYS05_RS12125	COG0517	IMP dehydrogenase activity
EYS05_RS12125	COG0516	GMP reductase activity
EYS05_RS12140	COG0138	bifunctional purine biosynthesis protein purh
EYS05_RS12165	COG1979	alcohol dehydrogenase
EYS05_RS12170	COG0492	ferredoxin-NADP+ reductase activity
EYS05_RS12205	COG5002	protein histidine kinase activity
EYS05_RS12210	COG0745	RESPONSE REGULATOR receiver
EYS05_RS12220	COG3481	metal-dependent phosphohydrolase, HD sub domain
EYS05_RS12225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYS05_RS12245	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EYS05_RS12250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYS05_RS12265	COG1192	Involved in chromosome partitioning
EYS05_RS12270	COG1475	DNA binding
EYS05_RS12335	COG0784	Response regulator, receiver
EYS05_RS12335	COG2205	protein histidine kinase activity
EYS05_RS12335	COG5002	protein histidine kinase activity
EYS05_RS12345	COG1917	Cupin 2, conserved barrel domain protein
EYS05_RS12345	COG2207	Transcriptional regulator
EYS05_RS12370	COG1874	Beta-galactosidase
EYS05_RS12380	COG5426	von Willebrand factor, type A
EYS05_RS12385	COG0657	acetylesterase activity
EYS05_RS12405	COG0148	phosphopyruvate hydratase activity
EYS05_RS12420	COG1691	(AIR) carboxylase
EYS05_RS12425	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EYS05_RS12440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS05_RS12445	COG3962	Belongs to the TPP enzyme family
EYS05_RS12455	COG1454	alcohol dehydrogenase
EYS05_RS12465	COG2211	Major facilitator Superfamily
EYS05_RS12470	COG2972	Histidine kinase
EYS05_RS12485	COG0673	inositol 2-dehydrogenase activity
EYS05_RS12490	COG1082	Xylose isomerase domain protein TIM barrel
EYS05_RS12495	COG0191	fructose-bisphosphate aldolase activity
EYS05_RS12500	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EYS05_RS12515	COG0037	tRNA processing
EYS05_RS12530	COG1191	sigma factor activity
EYS05_RS12545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EYS05_RS12550	COG0436	Aminotransferase
EYS05_RS12555	COG0372	Belongs to the citrate synthase family
EYS05_RS12560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EYS05_RS12565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EYS05_RS12580	COG0772	Belongs to the SEDS family
EYS05_RS12585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS05_RS12590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EYS05_RS12595	COG0210	DNA helicase
EYS05_RS12610	COG3854	ATPases associated with a variety of cellular activities
EYS05_RS12650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EYS05_RS12655	COG1302	Protein conserved in bacteria
EYS05_RS12660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EYS05_RS12665	COG1570	exodeoxyribonuclease VII activity
EYS05_RS12680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EYS05_RS12685	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EYS05_RS12690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EYS05_RS12695	COG1438	arginine binding
EYS05_RS12700	COG0497	DNA recombination
EYS05_RS12705	COG0750	zinc metalloprotease
EYS05_RS12710	COG0745	RESPONSE REGULATOR receiver
EYS05_RS12715	COG0297	glycogen (starch) synthase activity
EYS05_RS12720	COG1918	ferrous iron import across plasma membrane
EYS05_RS12720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EYS05_RS12730	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EYS05_RS12735	COG0163	prenyltransferase activity
EYS05_RS12750	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EYS05_RS12770	COG0583	DNA-binding transcription factor activity
EYS05_RS12775	COG2252	PERMEase
EYS05_RS12785	COG3706	GGDEF domain
EYS05_RS12790	COG0534	Mate efflux family protein
EYS05_RS12795	COG1982	Orn Lys Arg decarboxylase major
EYS05_RS12800	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EYS05_RS12805	COG0010	Belongs to the arginase family
EYS05_RS12820	COG1288	antiporter activity
EYS05_RS12825	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EYS05_RS12840	COG3177	Filamentation induced by cAMP protein fic
EYS05_RS12860	COG0348	domain, Protein
EYS05_RS12860	COG3901	Regulator of nitric oxide reductase transcription
EYS05_RS12880	COG1132	(ABC) transporter
EYS05_RS12885	COG1132	(ABC) transporter
EYS05_RS12890	COG1129	ABC transporter
EYS05_RS12915	COG3843	relaxase mobilization nuclease domain protein
EYS05_RS12925	COG2315	Protein conserved in bacteria
EYS05_RS12945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYS05_RS12970	COG1773	rubredoxin
EYS05_RS12985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EYS05_RS12995	COG1592	Rubrerythrin
EYS05_RS13000	COG2033	superoxide reductase activity
EYS05_RS13005	COG1773	rubredoxin
EYS05_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
EYS05_RS13020	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EYS05_RS13030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EYS05_RS13035	COG3118	belongs to the thioredoxin family
EYS05_RS13040	COG0492	ferredoxin-NADP+ reductase activity
EYS05_RS13080	COG1192	Involved in chromosome partitioning
EYS05_RS13085	COG1475	DNA binding
EYS05_RS13150	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13215	COG1484	DNA-dependent DNA replication
EYS05_RS13260	COG3706	GGDEF domain
EYS05_RS13260	COG2203	Gaf domain
EYS05_RS13260	COG5001	Diguanylate cyclase
EYS05_RS13260	COG4251	negative regulation of phosphorylation
EYS05_RS13265	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYS05_RS13375	COG0791	NLP P60 protein
EYS05_RS13375	COG0741	lytic transglycosylase activity
EYS05_RS13390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EYS05_RS13390	COG0551	DNA topoisomerase type I activity
EYS05_RS13410	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13415	COG5002	protein histidine kinase activity
EYS05_RS13435	COG1136	(ABC) transporter
EYS05_RS13440	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13540	COG1129	ABC transporter
EYS05_RS13545	COG1132	(ABC) transporter
EYS05_RS13545	COG2375	cellular response to nickel ion
EYS05_RS13550	COG1132	(ABC) transporter
EYS05_RS13555	COG1321	iron dependent repressor
EYS05_RS13560	COG1396	sequence-specific DNA binding
EYS05_RS13570	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13575	COG2205	protein histidine kinase activity
EYS05_RS13580	COG1136	(ABC) transporter
EYS05_RS13595	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13600	COG0768	penicillin binding
EYS05_RS13625	COG0745	RESPONSE REGULATOR receiver
EYS05_RS13630	COG3843	relaxase mobilization nuclease domain protein
EYS05_RS13640	COG2315	Protein conserved in bacteria
EYS05_RS13650	COG1396	sequence-specific DNA binding
EYS05_RS13695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EYS05_RS13700	COG4120	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS13710	COG0860	N-Acetylmuramoyl-L-alanine amidase
EYS05_RS13735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYS05_RS13740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYS05_RS13740	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EYS05_RS13745	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EYS05_RS13745	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EYS05_RS13755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EYS05_RS13765	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EYS05_RS13775	COG0124	histidyl-tRNA synthetase
EYS05_RS13780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EYS05_RS13785	COG0730	response to heat
EYS05_RS13800	COG1136	(ABC) transporter
EYS05_RS13810	COG0577	efflux transmembrane transporter activity
EYS05_RS13820	COG1307	EDD domain protein, DegV family
EYS05_RS13830	COG2815	serine threonine protein kinase
EYS05_RS13830	COG0515	serine threonine protein kinase
EYS05_RS13850	COG1725	Transcriptional regulator
EYS05_RS13855	COG1131	(ABC) transporter
EYS05_RS13865	COG1187	pseudouridine synthase activity
EYS05_RS13870	COG0052	Belongs to the universal ribosomal protein uS2 family
EYS05_RS13875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EYS05_RS13905	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYS05_RS13905	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EYS05_RS13920	COG1216	Glycosyl transferase, family 2
EYS05_RS13970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EYS05_RS14015	COG0066	3-isopropylmalate dehydratase activity
EYS05_RS14020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYS05_RS14025	COG0066	3-isopropylmalate dehydratase activity
EYS05_RS14030	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EYS05_RS14050	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EYS05_RS14080	COG1053	succinate dehydrogenase
EYS05_RS14085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EYS05_RS14085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EYS05_RS14100	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EYS05_RS14140	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EYS05_RS14145	COG2239	Acts as a magnesium transporter
EYS05_RS14150	COG1115	amino acid carrier protein
EYS05_RS14195	COG0366	Alpha amylase catalytic
EYS05_RS14210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EYS05_RS14245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EYS05_RS14250	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EYS05_RS14260	COG5012	cobalamin binding
EYS05_RS14305	COG3344	reverse transcriptase
EYS05_RS14310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EYS05_RS14320	COG1459	type II secretion system
EYS05_RS14330	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EYS05_RS14390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EYS05_RS14395	COG0488	(ABC) transporter
EYS05_RS14400	COG1522	sequence-specific DNA binding
EYS05_RS14410	COG4485	Bacterial membrane protein, YfhO
EYS05_RS14415	COG0463	Glycosyl transferase, family 2
EYS05_RS14420	COG2246	polysaccharide biosynthetic process
EYS05_RS14425	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EYS05_RS14435	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EYS05_RS14440	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
EYS05_RS14445	COG0588	phosphoglycerate mutase activity
EYS05_RS14455	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYS05_RS14455	COG3608	succinylglutamate desuccinylase aspartoacylase
EYS05_RS14460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EYS05_RS14465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EYS05_RS14490	COG0534	Mate efflux family protein
EYS05_RS14500	COG2357	RelA SpoT domain protein
EYS05_RS14510	COG0425	Belongs to the sulfur carrier protein TusA family
EYS05_RS14525	COG1846	Transcriptional regulator
EYS05_RS14545	COG1733	regulation of RNA biosynthetic process
EYS05_RS14590	COG3608	succinylglutamate desuccinylase aspartoacylase
EYS05_RS14590	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EYS05_RS14600	COG1854	S-ribosylhomocysteine lyase activity
EYS05_RS14605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EYS05_RS14610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EYS05_RS14620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EYS05_RS14625	COG0564	pseudouridine synthase activity
EYS05_RS14635	COG0438	transferase activity, transferring glycosyl groups
EYS05_RS14640	COG0535	radical SAM domain protein
EYS05_RS14645	COG0463	Glycosyl transferase, family 2
EYS05_RS14645	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EYS05_RS14650	COG3475	LICD family
EYS05_RS14670	COG1088	dTDP-glucose 4,6-dehydratase activity
EYS05_RS14675	COG3594	Acyltransferase
EYS05_RS14680	COG0346	lactoylglutathione lyase activity
EYS05_RS14700	COG0534	Mate efflux family protein
EYS05_RS14705	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EYS05_RS14750	COG1492	cobalamin metabolic process
EYS05_RS14760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EYS05_RS14770	COG0488	(ABC) transporter
EYS05_RS14775	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EYS05_RS14780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EYS05_RS14780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EYS05_RS14785	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EYS05_RS14790	COG2337	Toxic component of a toxin-antitoxin (TA) module
EYS05_RS14795	COG0217	transcriptional regulatory protein
EYS05_RS14800	COG0740	serine-type endopeptidase activity
EYS05_RS14810	COG0493	'glutamate synthase
EYS05_RS14815	COG1968	undecaprenyl-diphosphatase activity
EYS05_RS14830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EYS05_RS14845	COG0601	transmembrane transport
EYS05_RS14850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS05_RS14855	COG0444	Belongs to the ABC transporter superfamily
EYS05_RS14860	COG4608	Belongs to the ABC transporter superfamily
EYS05_RS14865	COG3681	Belongs to the UPF0597 family
EYS05_RS14895	COG1702	phosphate starvation-inducible protein PhoH
EYS05_RS14900	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EYS05_RS14915	COG4224	UPF0291 protein
EYS05_RS14920	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EYS05_RS14925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EYS05_RS14940	COG1131	(ABC) transporter
EYS05_RS14980	COG5001	Diguanylate cyclase
EYS05_RS14985	COG1686	Belongs to the peptidase S11 family
EYS05_RS14995	COG1408	metallophosphoesterase
EYS05_RS15000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EYS05_RS15005	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EYS05_RS15015	COG1686	Belongs to the peptidase S11 family
EYS05_RS15020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EYS05_RS15030	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EYS05_RS15035	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EYS05_RS15045	COG2081	HI0933 family
EYS05_RS15050	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EYS05_RS15055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYS05_RS15060	COG0539	negative regulation of cytoplasmic translation
EYS05_RS15060	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EYS05_RS15070	COG4656	Part of a membrane complex involved in electron transport
EYS05_RS15075	COG4658	electron transport chain
EYS05_RS15080	COG4659	FMN binding
EYS05_RS15085	COG4660	Part of a membrane complex involved in electron transport
EYS05_RS15090	COG4657	Part of a membrane complex involved in electron transport
EYS05_RS15095	COG2878	Part of a membrane complex involved in electron transport
EYS05_RS15105	COG0632	four-way junction helicase activity
EYS05_RS15110	COG2255	four-way junction helicase activity
EYS05_RS15125	COG3344	reverse transcriptase
EYS05_RS15150	COG0826	peptidase U32
EYS05_RS15160	COG0768	penicillin binding
EYS05_RS15185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EYS05_RS15195	COG1461	Dihydroxyacetone kinase
EYS05_RS15200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EYS05_RS15220	COG1803	Methylglyoxal synthase
EYS05_RS15225	COG0742	ribosomal rna small subunit methyltransferase
EYS05_RS15230	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EYS05_RS15245	COG2195	Cleaves the N-terminal amino acid of tripeptides
EYS05_RS15250	COG2357	RelA SpoT domain protein
EYS05_RS15265	COG0564	pseudouridine synthase activity
EYS05_RS15270	COG0681	Belongs to the peptidase S26 family
EYS05_RS15275	COG3331	DNA recombination
EYS05_RS15280	COG0124	histidyl-tRNA synthetase
EYS05_RS15285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EYS05_RS15290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EYS05_RS15295	COG0131	Imidazoleglycerol-phosphate dehydratase
EYS05_RS15305	COG3608	succinylglutamate desuccinylase aspartoacylase
EYS05_RS15310	COG0601	transmembrane transport
EYS05_RS15315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EYS05_RS15320	COG0747	negative chemotaxis
EYS05_RS15325	COG0444	Belongs to the ABC transporter superfamily
EYS05_RS15330	COG4608	Belongs to the ABC transporter superfamily
EYS05_RS15340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EYS05_RS15345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EYS05_RS15345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EYS05_RS15350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EYS05_RS15355	COG1418	mRNA catabolic process
EYS05_RS15385	COG0328	RNA-DNA hybrid ribonuclease activity
EYS05_RS15395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EYS05_RS15400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EYS05_RS15405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EYS05_RS15410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYS05_RS15415	COG1937	Protein conserved in bacteria
EYS05_RS15435	COG3344	reverse transcriptase
EYS05_RS15440	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
EYS05_RS15445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EYS05_RS15455	COG0351	phosphomethylpyrimidine kinase
EYS05_RS15455	COG0352	thiamine-phosphate diphosphorylase activity
EYS05_RS15460	COG0006	proline dipeptidase activity
EYS05_RS15465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EYS05_RS15470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EYS05_RS15495	COG1595	DNA-templated transcription, initiation
EYS05_RS15505	COG0367	asparagine synthase
EYS05_RS15515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EYS05_RS15590	COG0745	RESPONSE REGULATOR receiver
EYS05_RS15595	COG5002	protein histidine kinase activity
EYS05_RS15615	COG1131	(ABC) transporter
EYS05_RS15630	COG2234	aminopeptidase activity
EYS05_RS15665	COG1595	DNA-templated transcription, initiation
EYS05_RS15755	COG1396	sequence-specific DNA binding
EYS05_RS15810	COG3620	sequence-specific DNA binding
EYS05_RS15820	COG5002	protein histidine kinase activity
EYS05_RS15825	COG1136	(ABC) transporter
EYS05_RS15855	COG0629	single-stranded DNA binding
EYS05_RS15890	COG1131	(ABC) transporter
EYS05_RS15925	COG0582	viral genome integration into host DNA
EYS05_RS15930	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EYS05_RS15940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EYS05_RS15945	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EYS05_RS15950	COG2081	HI0933 family
EYS05_RS15955	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EYS05_RS15965	COG0443	Heat shock 70 kDa protein
EYS05_RS15985	COG2894	cell division
EYS05_RS15990	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EYS05_RS15995	COG0772	Belongs to the SEDS family
EYS05_RS16000	COG1686	Belongs to the peptidase S11 family
EYS05_RS16015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EYS05_RS16025	COG4286	Uncharacterised protein family (UPF0160)
EYS05_RS16035	COG0366	Alpha amylase catalytic
EYS05_RS16040	COG0372	Belongs to the citrate synthase family
EYS05_RS16050	COG0745	RESPONSE REGULATOR receiver
EYS05_RS16055	COG3850	Histidine kinase
EYS05_RS16055	COG5002	protein histidine kinase activity
EYS05_RS16065	COG1307	EDD domain protein, DegV family
EYS05_RS16070	COG0235	Class ii aldolase
EYS05_RS16080	COG4974	Belongs to the 'phage' integrase family
EYS05_RS16085	COG1490	D-aminoacyl-tRNA deacylase activity
EYS05_RS16090	COG0628	permease
EYS05_RS16100	COG0564	pseudouridine synthase activity
EYS05_RS16105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EYS05_RS16110	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EYS05_RS16125	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EYS05_RS16135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EYS05_RS16140	COG0799	negative regulation of ribosome biogenesis
EYS05_RS16145	COG1713	HD superfamily hydrolase involved in NAD metabolism
EYS05_RS16150	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EYS05_RS16155	COG1534	Rna-binding protein
EYS05_RS16160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EYS05_RS16165	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EYS05_RS16170	COG2868	ribosomal protein
EYS05_RS16175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EYS05_RS16205	COG1757	Na H antiporter
EYS05_RS16210	COG0166	Belongs to the GPI family
EYS05_RS16215	COG0561	phosphatase activity
EYS05_RS16225	COG1058	Belongs to the CinA family
EYS05_RS16225	COG1546	Belongs to the CinA family
EYS05_RS16230	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EYS05_RS16235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EYS05_RS16245	COG0194	GDP metabolic process
EYS05_RS16255	COG1561	YicC-like family, N-terminal region
EYS05_RS16275	COG0038	chloride channel
EYS05_RS16290	COG0495	leucyl-tRNA aminoacylation
EYS05_RS16295	COG1301	dicarboxylic acid transport
EYS05_RS16305	COG0366	Alpha amylase catalytic
EYS05_RS16320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EYS05_RS16325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EYS05_RS16330	COG0287	Prephenate dehydrogenase
EYS05_RS16340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EYS05_RS16350	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EYS05_RS16360	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EYS05_RS16365	COG0336	Belongs to the RNA methyltransferase TrmD family
EYS05_RS16370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EYS05_RS16385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EYS05_RS16400	COG3835	regulator
EYS05_RS16410	COG2267	carboxylic ester hydrolase activity
EYS05_RS16415	COG1283	sodium-dependent phosphate transmembrane transporter activity
EYS05_RS16425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EYS05_RS16430	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EYS05_RS16435	COG0552	protein localization to endoplasmic reticulum
EYS05_RS16440	COG1196	nuclear chromosome segregation
EYS05_RS16445	COG0571	ribonuclease III activity
EYS05_RS16450	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EYS05_RS16455	COG0416	fatty acid biosynthetic process
EYS05_RS16460	COG0488	(ABC) transporter
EYS05_RS16465	COG3279	Response regulator of the LytR AlgR family
EYS05_RS16480	COG0534	Mate efflux family protein
EYS05_RS16485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EYS05_RS16500	COG0280	phosphate acetyltransferase
EYS05_RS16510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EYS05_RS16510	COG1116	anion transmembrane transporter activity
EYS05_RS16515	COG4120	Belongs to the binding-protein-dependent transport system permease family
EYS05_RS16525	COG2848	UPF0210 protein
EYS05_RS16535	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EYS05_RS16540	COG0237	dephospho-CoA kinase activity
EYS05_RS16545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYS05_RS16545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EYS05_RS16555	COG1307	EDD domain protein, DegV family
EYS05_RS16560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS05_RS16570	COG0534	Mate efflux family protein
EYS05_RS16600	COG2706	6-phosphogluconolactonase activity
EYS05_RS16605	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EYS05_RS16610	COG0113	porphobilinogen synthase activity
EYS05_RS16620	COG0181	hydroxymethylbilane synthase activity
EYS05_RS16630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EYS05_RS16645	COG1404	Belongs to the peptidase S8 family
EYS05_RS16655	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EYS05_RS16685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EYS05_RS16690	COG3404	Formiminotransferase-cyclodeaminase
EYS05_RS16695	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EYS05_RS16735	COG1151	hydroxylamine reductase activity
EYS05_RS16745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EYS05_RS16760	COG0656	L-ascorbic acid biosynthetic process
EYS05_RS16770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EYS05_RS16785	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EYS05_RS16790	COG1496	oxidoreductase activity
EYS05_RS16795	COG0792	nuclease activity
EYS05_RS16800	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EYS05_RS16815	COG0335	large ribosomal subunit rRNA binding
EYS05_RS16865	COG0406	alpha-ribazole phosphatase activity
EYS05_RS16870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EYS05_RS16870	COG0072	phenylalanine-tRNA ligase activity
EYS05_RS16875	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EYS05_RS16890	COG2017	converts alpha-aldose to the beta-anomer
EYS05_RS16900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EYS05_RS16905	COG3773	Cell wall hydrolase
EYS05_RS16905	COG3409	Peptidoglycan-binding domain 1 protein
EYS05_RS16915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EYS05_RS16920	COG1472	Belongs to the glycosyl hydrolase 3 family
EYS05_RS16975	COG3475	LICD family
EYS05_RS16980	COG1215	transferase activity, transferring glycosyl groups
EYS05_RS17050	COG2365	Tyrosine phosphatase family
EYS05_RS17060	COG0561	phosphatase activity
EYS05_RS17065	COG1362	aminopeptidase activity
EYS05_RS17080	COG0750	zinc metalloprotease
EYS05_RS17090	COG4589	Belongs to the CDS family
EYS05_RS17100	COG0233	cytoplasmic translational termination
EYS05_RS17105	COG0528	UMP kinase activity
EYS05_RS17120	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EYS05_RS17125	COG0557	exoribonuclease II activity
EYS05_RS17130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EYS05_RS17135	COG0148	phosphopyruvate hydratase activity
EYS05_RS17140	COG0726	polysaccharide deacetylase
EYS05_RS17150	COG0482	sulfurtransferase activity
EYS05_RS17155	COG0659	secondary active sulfate transmembrane transporter activity
EYS05_RS17160	COG0583	DNA-binding transcription factor activity
EYS05_RS17170	COG1132	(ABC) transporter
EYS05_RS17180	COG1132	(ABC) transporter
EYS05_RS17185	COG2375	cellular response to nickel ion
EYS05_RS17185	COG1132	(ABC) transporter
EYS05_RS17195	COG1160	GTP binding
EYS05_RS17210	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EYS05_RS17220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EYS05_RS17235	COG0346	lactoylglutathione lyase activity
EYS05_RS17240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EYS05_RS17245	COG2610	gluconate transmembrane transporter activity
EYS05_RS17250	COG0246	Mannitol dehydrogenase
EYS05_RS17295	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EYS05_RS17305	COG0542	response to heat
EYS05_RS17320	COG0151	Belongs to the GarS family