locus-tag	class	description
NQ550_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQ550_RS00010	COG0592	DNA-directed DNA polymerase activity
NQ550_RS00015	COG2501	S4 domain
NQ550_RS00030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQ550_RS00040	COG2357	RelA SpoT domain protein
NQ550_RS00060	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ550_RS00065	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQ550_RS00070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQ550_RS00075	COG5002	protein histidine kinase activity
NQ550_RS00080	COG0745	RESPONSE REGULATOR receiver
NQ550_RS00085	COG1982	Orn Lys Arg decarboxylase major
NQ550_RS00090	COG0194	GDP metabolic process
NQ550_RS00095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQ550_RS00100	COG1774	PSP1 C-terminal conserved region
NQ550_RS00105	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NQ550_RS00110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NQ550_RS00115	COG0187	DNA topoisomerase II activity
NQ550_RS00120	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQ550_RS00215	COG1609	Transcriptional regulator
NQ550_RS00220	COG2190	(PTS) system
NQ550_RS00220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ550_RS00220	COG1263	PTS System
NQ550_RS00225	COG1621	beta-fructofuranosidase activity
NQ550_RS00260	COG1609	Transcriptional regulator
NQ550_RS00270	COG0395	ABC-type sugar transport system, permease component
NQ550_RS00275	COG3833	ABC-type maltose transport systems, permease component
NQ550_RS00295	COG1874	Beta-galactosidase
NQ550_RS00300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NQ550_RS00305	COG2002	toxin-antitoxin pair type II binding
NQ550_RS00315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NQ550_RS00370	COG2205	protein histidine kinase activity
NQ550_RS00380	COG0235	Class ii aldolase
NQ550_RS00400	COG2996	Protein conserved in bacteria
NQ550_RS00415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQ550_RS00420	COG0569	domain protein
NQ550_RS00425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ550_RS00445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQ550_RS00450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NQ550_RS00450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NQ550_RS00460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NQ550_RS00465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQ550_RS00470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQ550_RS00475	COG4166	transmembrane transport
NQ550_RS00480	COG0444	Belongs to the ABC transporter superfamily
NQ550_RS00485	COG4608	Belongs to the ABC transporter superfamily
NQ550_RS00490	COG0601	transmembrane transport
NQ550_RS00495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ550_RS00500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQ550_RS00520	COG1686	Belongs to the peptidase S11 family
NQ550_RS00525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NQ550_RS00530	COG0058	SHG alpha-glucan phosphorylase activity
NQ550_RS00570	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ550_RS00655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NQ550_RS00660	COG1802	Transcriptional regulator
NQ550_RS00665	COG0697	spore germination
NQ550_RS00680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQ550_RS00705	COG0544	peptidyl-prolyl cis-trans isomerase activity
NQ550_RS00725	COG0523	cobalamin synthesis protein
NQ550_RS00740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NQ550_RS00765	COG1254	Belongs to the acylphosphatase family
NQ550_RS00805	COG0601	transmembrane transport
NQ550_RS00810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ550_RS00815	COG0747	negative chemotaxis
NQ550_RS00820	COG0444	Belongs to the ABC transporter superfamily
NQ550_RS00825	COG4608	Belongs to the ABC transporter superfamily
NQ550_RS00835	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ550_RS00850	COG1454	alcohol dehydrogenase
NQ550_RS00855	COG2357	RelA SpoT domain protein
NQ550_RS00860	COG2199	diguanylate cyclase activity
NQ550_RS00870	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NQ550_RS00895	COG0745	RESPONSE REGULATOR receiver
NQ550_RS00915	COG0358	DNA primase activity
NQ550_RS00985	COG0395	ABC-type sugar transport system, permease component
NQ550_RS00995	COG1609	Transcriptional regulator
NQ550_RS01000	COG3534	alpha-L-arabinofuranosidase
NQ550_RS01005	COG3534	alpha-L-arabinofuranosidase
NQ550_RS01025	COG3940	Belongs to the glycosyl hydrolase 43 family
NQ550_RS01030	COG3507	Belongs to the glycosyl hydrolase 43 family
NQ550_RS01040	COG1653	transport
NQ550_RS01045	COG1175	transmembrane transport
NQ550_RS01050	COG0395	ABC-type sugar transport system, permease component
NQ550_RS01055	COG3534	alpha-L-arabinofuranosidase
NQ550_RS01065	COG0363	glucosamine-6-phosphate deaminase activity
NQ550_RS01070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NQ550_RS01075	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NQ550_RS01080	COG1737	Transcriptional regulator
NQ550_RS01085	COG1175	transmembrane transport
NQ550_RS01095	COG1653	transport
NQ550_RS01100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ550_RS01105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ550_RS01110	COG1846	Transcriptional regulator
NQ550_RS01110	COG1940	carbohydrate kinase activity
NQ550_RS01120	COG0657	acetylesterase activity
NQ550_RS01135	COG2022	thiamine diphosphate biosynthetic process
NQ550_RS01145	COG0352	thiamine-phosphate diphosphorylase activity
NQ550_RS01150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NQ550_RS01155	COG1349	DNA-binding transcription factor activity
NQ550_RS01160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NQ550_RS01165	COG3959	Transketolase, thiamine diphosphate binding domain
NQ550_RS01170	COG3958	Transketolase
NQ550_RS01175	COG1063	alcohol dehydrogenase
NQ550_RS01185	COG1129	ABC transporter
NQ550_RS01190	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS01215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NQ550_RS01225	COG0058	SHG alpha-glucan phosphorylase activity
NQ550_RS01230	COG2207	Transcriptional regulator
NQ550_RS01230	COG1917	Cupin 2, conserved barrel domain protein
NQ550_RS01275	COG1451	nucleotide metabolic process
NQ550_RS01285	COG1379	DNA repair
NQ550_RS01305	COG1380	Effector of murein hydrolase LrgA
NQ550_RS01310	COG1346	cytolysis
NQ550_RS01320	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NQ550_RS01320	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NQ550_RS01335	COG1595	DNA-templated transcription, initiation
NQ550_RS01340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQ550_RS01375	COG0356	it plays a direct role in the translocation of protons across the membrane
NQ550_RS01380	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ550_RS01385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NQ550_RS01390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ550_RS01400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQ550_RS01405	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NQ550_RS01410	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NQ550_RS01420	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
NQ550_RS01480	COG0705	Rhomboid family
NQ550_RS01480	COG0457	Tetratricopeptide repeat
NQ550_RS01485	COG5002	protein histidine kinase activity
NQ550_RS01490	COG0537	adenosine 5'-monophosphoramidase activity
NQ550_RS01500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQ550_RS01510	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NQ550_RS01520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQ550_RS01540	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NQ550_RS01550	COG0017	Asparaginyl-tRNA synthetase
NQ550_RS01565	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NQ550_RS01570	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQ550_RS01585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQ550_RS01590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQ550_RS01595	COG2088	sporulation resulting in formation of a cellular spore
NQ550_RS01605	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS01620	COG0590	tRNA wobble adenosine to inosine editing
NQ550_RS01625	COG0534	Mate efflux family protein
NQ550_RS01635	COG0205	6-phosphofructokinase activity
NQ550_RS01640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQ550_RS01645	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQ550_RS01650	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NQ550_RS01665	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NQ550_RS01670	COG3958	Transketolase
NQ550_RS01825	COG3547	Transposase (IS116 IS110 IS902 family)
NQ550_RS01865	COG1362	aminopeptidase activity
NQ550_RS01870	COG0577	efflux transmembrane transporter activity
NQ550_RS01870	COG1136	(ABC) transporter
NQ550_RS01880	COG0577	efflux transmembrane transporter activity
NQ550_RS01895	COG1120	ATPase activity
NQ550_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ550_RS01915	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ550_RS01915	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NQ550_RS01925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQ550_RS01960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS01975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQ550_RS02030	COG1070	Carbohydrate kinase
NQ550_RS02035	COG0583	DNA-binding transcription factor activity
NQ550_RS02040	COG1027	Aspartate ammonia-lyase
NQ550_RS02045	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NQ550_RS02050	COG1982	Orn Lys Arg decarboxylase major
NQ550_RS02100	COG2160	L-arabinose isomerase activity
NQ550_RS02125	COG4753	response regulator
NQ550_RS02125	COG2207	Transcriptional regulator
NQ550_RS02130	COG2972	Histidine kinase
NQ550_RS02145	COG1175	transmembrane transport
NQ550_RS02150	COG0395	ABC-type sugar transport system, permease component
NQ550_RS02165	COG1082	Xylose isomerase domain protein TIM barrel
NQ550_RS02180	COG1484	DNA-dependent DNA replication
NQ550_RS02200	COG0622	Phosphoesterase
NQ550_RS02205	COG0116	Belongs to the methyltransferase superfamily
NQ550_RS02210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NQ550_RS02215	COG0622	Phosphoesterase
NQ550_RS02280	COG3328	transposase activity
NQ550_RS02290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS02355	COG1131	(ABC) transporter
NQ550_RS02365	COG2252	PERMEase
NQ550_RS02375	COG0628	permease
NQ550_RS02390	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NQ550_RS02395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NQ550_RS02400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NQ550_RS02405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQ550_RS02445	COG3706	GGDEF domain
NQ550_RS02485	COG0463	Glycosyl transferase, family 2
NQ550_RS02485	COG1216	Glycosyl transferase, family 2
NQ550_RS02510	COG1555	photosystem II stabilization
NQ550_RS02510	COG1596	polysaccharide export
NQ550_RS02515	COG0745	RESPONSE REGULATOR receiver
NQ550_RS02530	COG3383	formate dehydrogenase (NAD+) activity
NQ550_RS02560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NQ550_RS02575	COG0746	molybdenum cofactor guanylyltransferase activity
NQ550_RS02595	COG3209	COG3209 Rhs family protein
NQ550_RS02605	COG5002	protein histidine kinase activity
NQ550_RS02615	COG2333	competence protein COMEC
NQ550_RS02615	COG0658	competence protein
NQ550_RS02625	COG0157	Belongs to the NadC ModD family
NQ550_RS02630	COG1827	regulation of RNA biosynthetic process
NQ550_RS02635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NQ550_RS02645	COG0268	Binds directly to 16S ribosomal RNA
NQ550_RS02650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NQ550_RS02660	COG0481	GTPase activity
NQ550_RS02670	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQ550_RS02685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQ550_RS02690	COG1040	competence protein
NQ550_RS02705	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NQ550_RS02720	COG1376	ErfK ybiS ycfS ynhG family protein
NQ550_RS02740	COG0463	Glycosyl transferase, family 2
NQ550_RS02750	COG0151	Belongs to the GarS family
NQ550_RS02755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NQ550_RS02760	COG1686	Belongs to the peptidase S11 family
NQ550_RS02770	COG1682	transport, permease protein
NQ550_RS02785	COG1216	Glycosyl transferase, family 2
NQ550_RS02785	COG0438	transferase activity, transferring glycosyl groups
NQ550_RS02790	COG0438	transferase activity, transferring glycosyl groups
NQ550_RS02790	COG1216	Glycosyl transferase, family 2
NQ550_RS02800	COG1686	Belongs to the peptidase S11 family
NQ550_RS02805	COG0438	transferase activity, transferring glycosyl groups
NQ550_RS02805	COG1216	Glycosyl transferase, family 2
NQ550_RS02810	COG0463	Glycosyl transferase, family 2
NQ550_RS02820	COG1316	TRANSCRIPTIONal
NQ550_RS02830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQ550_RS02835	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NQ550_RS02875	COG1910	domain protein
NQ550_RS02880	COG3585	molybdate ion transport
NQ550_RS02885	COG0725	ABC transporter, periplasmic molybdate-binding protein
NQ550_RS02890	COG4149	molybdate abc transporter
NQ550_RS02895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NQ550_RS02900	COG3835	regulator
NQ550_RS02905	COG3842	ATPase activity
NQ550_RS02910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQ550_RS02915	COG1476	TRANSCRIPTIONal
NQ550_RS02930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQ550_RS02945	COG1957	nucleoside hydrolase
NQ550_RS02960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ550_RS02995	COG1695	Transcriptional regulator
NQ550_RS03000	COG0772	Belongs to the SEDS family
NQ550_RS03015	COG3279	Response regulator of the LytR AlgR family
NQ550_RS03055	COG1131	(ABC) transporter
NQ550_RS03065	COG3328	transposase activity
NQ550_RS03085	COG5002	protein histidine kinase activity
NQ550_RS03105	COG0534	Mate efflux family protein
NQ550_RS03110	COG1490	D-aminoacyl-tRNA deacylase activity
NQ550_RS03115	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NQ550_RS03120	COG2954	triphosphatase activity
NQ550_RS03125	COG1473	amidohydrolase
NQ550_RS03135	COG0544	peptidyl-prolyl cis-trans isomerase activity
NQ550_RS03150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQ550_RS03155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NQ550_RS03160	COG1122	ATPase activity
NQ550_RS03170	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NQ550_RS03175	COG0101	tRNA pseudouridine synthase activity
NQ550_RS03200	COG3620	sequence-specific DNA binding
NQ550_RS03215	COG5002	protein histidine kinase activity
NQ550_RS03220	COG1136	(ABC) transporter
NQ550_RS03250	COG0745	RESPONSE REGULATOR receiver
NQ550_RS03255	COG2205	protein histidine kinase activity
NQ550_RS03280	COG2205	protein histidine kinase activity
NQ550_RS03285	COG0745	RESPONSE REGULATOR receiver
NQ550_RS03290	COG1131	(ABC) transporter
NQ550_RS03320	COG0733	neurotransmitter:sodium symporter activity
NQ550_RS03335	COG0352	thiamine-phosphate diphosphorylase activity
NQ550_RS03335	COG0351	phosphomethylpyrimidine kinase
NQ550_RS03340	COG4667	esterase of the alpha-beta hydrolase superfamily
NQ550_RS03350	COG1175	transmembrane transport
NQ550_RS03355	COG0395	ABC-type sugar transport system, permease component
NQ550_RS03365	COG2207	Transcriptional regulator
NQ550_RS03365	COG4753	response regulator
NQ550_RS03370	COG2972	Histidine kinase
NQ550_RS03375	COG2188	Transcriptional regulator
NQ550_RS03380	COG1131	(ABC) transporter
NQ550_RS03395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ550_RS03400	COG1120	ATPase activity
NQ550_RS03425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQ550_RS03430	COG1283	sodium-dependent phosphate transmembrane transporter activity
NQ550_RS03435	COG0745	RESPONSE REGULATOR receiver
NQ550_RS03440	COG5002	protein histidine kinase activity
NQ550_RS03445	COG1653	transport
NQ550_RS03465	COG0395	ABC-type sugar transport system, permease component
NQ550_RS03480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQ550_RS03495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQ550_RS03500	COG0584	glycerophosphoryl diester phosphodiesterase
NQ550_RS03505	COG4868	Belongs to the UPF0371 family
NQ550_RS03510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ550_RS03515	COG0322	excinuclease ABC activity
NQ550_RS03520	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NQ550_RS03525	COG1940	carbohydrate kinase activity
NQ550_RS03530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NQ550_RS03535	COG1739	Uncharacterized protein family UPF0029
NQ550_RS03540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ550_RS03545	COG0802	atpase or kinase
NQ550_RS03550	COG1214	PFAM Peptidase M22, glycoprotease
NQ550_RS03555	COG0456	acetyltransferase
NQ550_RS03560	COG1234	tRNA 3'-trailer cleavage
NQ550_RS03565	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQ550_RS03570	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ550_RS03650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQ550_RS03670	COG4509	Sortase family
NQ550_RS03710	COG3279	Response regulator of the LytR AlgR family
NQ550_RS03725	COG0641	radical SAM
NQ550_RS03735	COG3279	Response regulator of the LytR AlgR family
NQ550_RS03755	COG1132	(ABC) transporter
NQ550_RS03770	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS03785	COG0577	efflux transmembrane transporter activity
NQ550_RS03785	COG1136	(ABC) transporter
NQ550_RS03795	COG2205	protein histidine kinase activity
NQ550_RS03800	COG0745	RESPONSE REGULATOR receiver
NQ550_RS03805	COG1396	sequence-specific DNA binding
NQ550_RS03815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQ550_RS03900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQ550_RS03910	COG2801	Transposase and inactivated derivatives
NQ550_RS03985	COG0745	RESPONSE REGULATOR receiver
NQ550_RS04030	COG2205	protein histidine kinase activity
NQ550_RS04075	COG0741	lytic transglycosylase activity
NQ550_RS04075	COG0791	NLP P60 protein
NQ550_RS04105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS04130	COG0745	RESPONSE REGULATOR receiver
NQ550_RS04220	COG0535	radical SAM domain protein
NQ550_RS04225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS04235	COG1131	(ABC) transporter
NQ550_RS04280	COG1247	-acetyltransferase
NQ550_RS04290	COG3279	Response regulator of the LytR AlgR family
NQ550_RS04340	COG0205	6-phosphofructokinase activity
NQ550_RS04345	COG1132	(ABC) transporter
NQ550_RS04365	COG4509	Sortase family
NQ550_RS04370	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQ550_RS04375	COG4481	Protein conserved in bacteria
NQ550_RS04380	COG0360	Binds together with S18 to 16S ribosomal RNA
NQ550_RS04385	COG0629	single-stranded DNA binding
NQ550_RS04390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NQ550_RS04395	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NQ550_RS04400	COG0359	binds to the 23S rRNA
NQ550_RS04405	COG0305	Participates in initiation and elongation during chromosome replication
NQ550_RS04415	COG2768	binding domain, Protein
NQ550_RS04425	COG3845	ABC transporter
NQ550_RS04430	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS04435	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS04445	COG4862	establishment of competence for transformation
NQ550_RS04460	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ550_RS04485	COG0009	L-threonylcarbamoyladenylate synthase
NQ550_RS04490	COG0698	ribose 5-phosphate isomerase
NQ550_RS04500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQ550_RS04505	COG0617	tRNA 3'-terminal CCA addition
NQ550_RS04515	COG0776	regulation of translation
NQ550_RS04520	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NQ550_RS04545	COG0037	tRNA processing
NQ550_RS04555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ550_RS04605	COG2972	Histidine kinase
NQ550_RS04610	COG4753	response regulator
NQ550_RS04610	COG2207	Transcriptional regulator
NQ550_RS04620	COG1175	transmembrane transport
NQ550_RS04625	COG0395	ABC-type sugar transport system, permease component
NQ550_RS04640	COG0330	HflC and HflK could
NQ550_RS04645	COG0330	HflC and HflK could
NQ550_RS04690	COG0426	domain, Protein
NQ550_RS04700	COG1595	DNA-templated transcription, initiation
NQ550_RS04710	COG0281	malic enzyme
NQ550_RS04735	COG0534	Mate efflux family protein
NQ550_RS04745	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NQ550_RS04760	COG1045	serine acetyltransferase
NQ550_RS04785	COG2155	Conserved Protein
NQ550_RS04825	COG2197	response regulator
NQ550_RS04850	COG1175	transmembrane transport
NQ550_RS04870	COG1917	Cupin 2, conserved barrel domain protein
NQ550_RS04870	COG2207	Transcriptional regulator
NQ550_RS04875	COG0366	Alpha amylase catalytic
NQ550_RS04885	COG0366	Alpha amylase catalytic
NQ550_RS04890	COG1597	lipid kinase activity
NQ550_RS04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQ550_RS04920	COG3853	Toxic anion resistance protein (TelA)
NQ550_RS04925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NQ550_RS04935	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NQ550_RS04940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NQ550_RS04950	COG1396	sequence-specific DNA binding
NQ550_RS04955	COG0606	chelatase, subunit chli
NQ550_RS04960	COG0758	DNA mediated transformation
NQ550_RS04965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ550_RS04975	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NQ550_RS04990	COG0516	GMP reductase activity
NQ550_RS04990	COG0517	IMP dehydrogenase activity
NQ550_RS05005	COG0138	bifunctional purine biosynthesis protein purh
NQ550_RS05040	COG1979	alcohol dehydrogenase
NQ550_RS05060	COG2972	Histidine kinase
NQ550_RS05065	COG4753	response regulator
NQ550_RS05065	COG2207	Transcriptional regulator
NQ550_RS05070	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ550_RS05085	COG0492	ferredoxin-NADP+ reductase activity
NQ550_RS05110	COG1309	transcriptional regulator
NQ550_RS05115	COG4716	Myosin-crossreactive antigen
NQ550_RS05125	COG5002	protein histidine kinase activity
NQ550_RS05130	COG0745	RESPONSE REGULATOR receiver
NQ550_RS05155	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQ550_RS05165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NQ550_RS05230	COG1484	DNA-dependent DNA replication
NQ550_RS05275	COG3279	Response regulator of the LytR AlgR family
NQ550_RS05310	COG1131	(ABC) transporter
NQ550_RS05415	COG1971	Probably functions as a manganese efflux pump
NQ550_RS05420	COG4086	secreted protein
NQ550_RS05430	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NQ550_RS05455	COG1748	Saccharopine dehydrogenase
NQ550_RS05465	COG1388	LysM domain
NQ550_RS05465	COG0791	NLP P60 protein
NQ550_RS05465	COG3103	Sh3 type 3 domain protein
NQ550_RS05505	COG1882	Formate acetyltransferase
NQ550_RS05510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NQ550_RS05515	COG0235	Class ii aldolase
NQ550_RS05525	COG1063	alcohol dehydrogenase
NQ550_RS05550	COG4869	propanediol catabolic process
NQ550_RS05555	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
NQ550_RS05560	COG4656	Part of a membrane complex involved in electron transport
NQ550_RS05570	COG1349	DNA-binding transcription factor activity
NQ550_RS05585	COG2207	Transcriptional regulator
NQ550_RS05585	COG1917	Cupin 2, conserved barrel domain protein
NQ550_RS05590	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NQ550_RS05595	COG4154	Belongs to the RbsD FucU family
NQ550_RS05600	COG2207	Transcriptional regulator
NQ550_RS05600	COG4753	response regulator
NQ550_RS05605	COG2972	Histidine kinase
NQ550_RS05615	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS05620	COG1129	ABC transporter
NQ550_RS05625	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS05635	COG1070	Carbohydrate kinase
NQ550_RS05640	COG0037	tRNA processing
NQ550_RS05650	COG1691	(AIR) carboxylase
NQ550_RS05655	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NQ550_RS05725	COG1115	amino acid carrier protein
NQ550_RS05765	COG0366	Alpha amylase catalytic
NQ550_RS05765	COG3103	Sh3 type 3 domain protein
NQ550_RS05785	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NQ550_RS05790	COG1122	ATPase activity
NQ550_RS05810	COG1720	tRNA m6t6A37 methyltransferase activity
NQ550_RS05815	COG0527	aspartate kinase activity
NQ550_RS05830	COG0371	Dehydrogenase
NQ550_RS05835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NQ550_RS05840	COG0215	cysteine-tRNA ligase activity
NQ550_RS05850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ550_RS05865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQ550_RS05880	COG0546	phosphoglycolate phosphatase activity
NQ550_RS05885	COG0561	phosphatase activity
NQ550_RS05905	COG0745	RESPONSE REGULATOR receiver
NQ550_RS05925	COG1278	Cold shock
NQ550_RS05930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQ550_RS05940	COG0543	2 iron, 2 sulfur cluster binding
NQ550_RS05945	COG0167	dihydroorotate dehydrogenase activity
NQ550_RS05975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NQ550_RS05980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NQ550_RS05990	COG0151	Belongs to the GarS family
NQ550_RS06010	COG0542	response to heat
NQ550_RS06020	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NQ550_RS06025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQ550_RS06030	COG0733	neurotransmitter:sodium symporter activity
NQ550_RS06035	COG0583	DNA-binding transcription factor activity
NQ550_RS06075	COG3279	Response regulator of the LytR AlgR family
NQ550_RS06145	COG1131	(ABC) transporter
NQ550_RS06170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ550_RS06175	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NQ550_RS06180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NQ550_RS06180	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ550_RS06185	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ550_RS06190	COG2169	Transcriptional regulator
NQ550_RS06205	COG4215	(ABC) transporter
NQ550_RS06210	COG1126	abc transporter atp-binding protein
NQ550_RS06225	COG0148	phosphopyruvate hydratase activity
NQ550_RS06230	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NQ550_RS06235	COG0557	exoribonuclease II activity
NQ550_RS06240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NQ550_RS06255	COG0528	UMP kinase activity
NQ550_RS06260	COG0233	cytoplasmic translational termination
NQ550_RS06265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQ550_RS06270	COG0575	Belongs to the CDS family
NQ550_RS06275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NQ550_RS06280	COG0750	zinc metalloprotease
NQ550_RS06290	COG1811	Na channel or pump
NQ550_RS06305	COG0163	prenyltransferase activity
NQ550_RS06325	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NQ550_RS06330	COG0358	DNA primase activity
NQ550_RS06335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NQ550_RS06345	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NQ550_RS06350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQ550_RS06360	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NQ550_RS06365	COG0540	Belongs to the ATCase OTCase family
NQ550_RS06375	COG0285	dihydrofolate synthase activity
NQ550_RS06380	COG0077	Prephenate dehydratase
NQ550_RS06380	COG1605	Chorismate mutase
NQ550_RS06395	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NQ550_RS06405	COG0187	DNA topoisomerase II activity
NQ550_RS06410	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQ550_RS06415	COG0779	Required for maturation of 30S ribosomal subunits
NQ550_RS06420	COG0195	Participates in both transcription termination and antitermination
NQ550_RS06425	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NQ550_RS06435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQ550_RS06435	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQ550_RS06440	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NQ550_RS06450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NQ550_RS06455	COG0196	riboflavin kinase activity
NQ550_RS06460	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NQ550_RS06465	COG1185	polyribonucleotide nucleotidyltransferase activity
NQ550_RS06470	COG0602	queuosine metabolic process
NQ550_RS06475	COG0756	dUTP diphosphatase activity
NQ550_RS06480	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NQ550_RS06490	COG3250	beta-galactosidase activity
NQ550_RS06500	COG0708	Exodeoxyribonuclease III
NQ550_RS06515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQ550_RS06520	COG0562	UDP-galactopyranose mutase
NQ550_RS06535	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQ550_RS06540	COG1381	Involved in DNA repair and RecF pathway recombination
NQ550_RS06550	COG1914	H( )-stimulated, divalent metal cation uptake system
NQ550_RS06555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NQ550_RS06560	COG1984	allophanate hydrolase subunit 2
NQ550_RS06565	COG0511	ligase activity, forming carbon-carbon bonds
NQ550_RS06570	COG0439	Biotin carboxylase
NQ550_RS06575	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NQ550_RS06585	COG2358	TRAP transporter, solute receptor (TAXI family
NQ550_RS06600	COG1088	dTDP-glucose 4,6-dehydratase activity
NQ550_RS06610	COG0789	Transcriptional regulator
NQ550_RS06610	COG4978	Transcriptional regulator
NQ550_RS06630	COG0534	Mate efflux family protein
NQ550_RS06640	COG2873	o-acetylhomoserine
NQ550_RS06645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQ550_RS06650	COG1116	anion transmembrane transporter activity
NQ550_RS06660	COG1183	phosphatidylcholine synthase activity
NQ550_RS06665	COG0688	phosphatidylethanolamine metabolic process
NQ550_RS06675	COG0165	Argininosuccinate lyase
NQ550_RS06690	COG0709	Synthesizes selenophosphate from selenide and ATP
NQ550_RS06695	COG2116	formate transmembrane transporter activity
NQ550_RS06700	COG0551	DNA topoisomerase type I activity
NQ550_RS06700	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ550_RS06705	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQ550_RS06765	COG2860	membrane
NQ550_RS06785	COG3279	Response regulator of the LytR AlgR family
NQ550_RS06825	COG0004	ammonium transporteR
NQ550_RS06835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NQ550_RS06845	COG0504	CTP synthase activity
NQ550_RS06850	COG0070	glutamate synthase
NQ550_RS06850	COG0069	glutamate synthase activity
NQ550_RS06850	COG0067	glutamate synthase
NQ550_RS06855	COG0493	'glutamate synthase
NQ550_RS06880	COG4152	abc transporter atp-binding protein
NQ550_RS06895	COG1598	PFAM Uncharacterised protein family UPF0150
NQ550_RS06910	COG0017	Asparaginyl-tRNA synthetase
NQ550_RS06915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQ550_RS06930	COG0436	Aminotransferase
NQ550_RS06945	COG1373	ATPase (AAA superfamily
NQ550_RS06980	COG3304	Inner membrane component domain
NQ550_RS07000	COG1192	Involved in chromosome partitioning
NQ550_RS07030	COG1401	restriction endodeoxyribonuclease activity
NQ550_RS07055	COG1484	DNA-dependent DNA replication
NQ550_RS07120	COG0242	peptide deformylase activity
NQ550_RS07125	COG0346	lactoylglutathione lyase activity
NQ550_RS07130	COG1671	Belongs to the UPF0178 family
NQ550_RS07135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ550_RS07145	COG0302	gtp cyclohydrolase
NQ550_RS07155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NQ550_RS07160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NQ550_RS07160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NQ550_RS07165	COG3257	ureidoglycine aminohydrolase activity
NQ550_RS07170	COG1362	aminopeptidase activity
NQ550_RS07175	COG0561	phosphatase activity
NQ550_RS07190	COG0440	acetolactate synthase activity
NQ550_RS07210	COG3279	Response regulator of the LytR AlgR family
NQ550_RS07230	COG0425	Belongs to the sulfur carrier protein TusA family
NQ550_RS07250	COG1854	S-ribosylhomocysteine lyase activity
NQ550_RS07255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ550_RS07260	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
NQ550_RS07265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQ550_RS07270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NQ550_RS07275	COG0564	pseudouridine synthase activity
NQ550_RS07280	COG0534	Mate efflux family protein
NQ550_RS07285	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NQ550_RS07320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ550_RS07325	COG1492	cobalamin metabolic process
NQ550_RS07335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ550_RS07355	COG0640	Transcriptional regulator
NQ550_RS07365	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQ550_RS07370	COG0569	domain protein
NQ550_RS07375	COG2205	protein histidine kinase activity
NQ550_RS07380	COG0745	RESPONSE REGULATOR receiver
NQ550_RS07395	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NQ550_RS07405	COG0181	hydroxymethylbilane synthase activity
NQ550_RS07415	COG0113	porphobilinogen synthase activity
NQ550_RS07420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NQ550_RS07425	COG2706	6-phosphogluconolactonase activity
NQ550_RS07470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ550_RS07480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQ550_RS07480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQ550_RS07485	COG0237	dephospho-CoA kinase activity
NQ550_RS07490	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NQ550_RS07500	COG2848	UPF0210 protein
NQ550_RS07515	COG4120	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS07520	COG1116	anion transmembrane transporter activity
NQ550_RS07520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQ550_RS07550	COG0280	phosphate acetyltransferase
NQ550_RS07565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQ550_RS07595	COG0488	(ABC) transporter
NQ550_RS07600	COG0416	fatty acid biosynthetic process
NQ550_RS07605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQ550_RS07610	COG0571	ribonuclease III activity
NQ550_RS07615	COG1196	nuclear chromosome segregation
NQ550_RS07620	COG0552	protein localization to endoplasmic reticulum
NQ550_RS07625	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQ550_RS07660	COG1129	ABC transporter
NQ550_RS07665	COG1132	(ABC) transporter
NQ550_RS07665	COG2375	cellular response to nickel ion
NQ550_RS07670	COG1132	(ABC) transporter
NQ550_RS07695	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NQ550_RS07710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NQ550_RS07715	COG0336	Belongs to the RNA methyltransferase TrmD family
NQ550_RS07720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NQ550_RS07740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ550_RS07750	COG0287	Prephenate dehydrogenase
NQ550_RS07755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQ550_RS07760	COG0495	leucyl-tRNA aminoacylation
NQ550_RS07765	COG0534	Mate efflux family protein
NQ550_RS07770	COG0488	(ABC) transporter
NQ550_RS07775	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NQ550_RS07780	COG1561	YicC-like family, N-terminal region
NQ550_RS07790	COG0194	GDP metabolic process
NQ550_RS07800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ550_RS07805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NQ550_RS07845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQ550_RS07850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NQ550_RS07855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQ550_RS07860	COG1686	Belongs to the peptidase S11 family
NQ550_RS07875	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NQ550_RS07880	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQ550_RS07890	COG1686	Belongs to the peptidase S11 family
NQ550_RS07895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ550_RS07935	COG0745	RESPONSE REGULATOR receiver
NQ550_RS07940	COG2205	protein histidine kinase activity
NQ550_RS07980	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NQ550_RS07985	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NQ550_RS07990	COG1447	Phosphotransferase system cellobiose-specific component IIA
NQ550_RS07995	COG2723	6-phospho-beta-galactosidase activity
NQ550_RS08035	COG0745	RESPONSE REGULATOR receiver
NQ550_RS08040	COG2205	protein histidine kinase activity
NQ550_RS08045	COG1131	(ABC) transporter
NQ550_RS08060	COG5002	protein histidine kinase activity
NQ550_RS08065	COG0745	RESPONSE REGULATOR receiver
NQ550_RS08075	COG1131	(ABC) transporter
NQ550_RS08110	COG3344	reverse transcriptase
NQ550_RS08175	COG3275	phosphorelay sensor kinase activity
NQ550_RS08185	COG1653	transport
NQ550_RS08190	COG1175	transmembrane transport
NQ550_RS08195	COG0395	ABC-type sugar transport system, permease component
NQ550_RS08200	COG4753	response regulator
NQ550_RS08200	COG2207	Transcriptional regulator
NQ550_RS08205	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ550_RS08210	COG4989	oxidoreductase activity
NQ550_RS08215	COG3681	Belongs to the UPF0597 family
NQ550_RS08225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQ550_RS08235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQ550_RS08245	COG0511	ligase activity, forming carbon-carbon bonds
NQ550_RS08250	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NQ550_RS08260	COG2081	HI0933 family
NQ550_RS08265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQ550_RS08270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQ550_RS08275	COG0539	negative regulation of cytoplasmic translation
NQ550_RS08275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQ550_RS08320	COG0562	UDP-galactopyranose mutase
NQ550_RS08335	COG1882	Formate acetyltransferase
NQ550_RS08340	COG3475	LICD family
NQ550_RS08345	COG0438	transferase activity, transferring glycosyl groups
NQ550_RS08355	COG1088	dTDP-glucose 4,6-dehydratase activity
NQ550_RS08675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQ550_RS08690	COG3344	reverse transcriptase
NQ550_RS08695	COG1484	DNA-dependent DNA replication
NQ550_RS08700	COG2390	Transcriptional regulator
NQ550_RS08700	COG4584	PFAM Integrase catalytic
NQ550_RS08705	COG2205	protein histidine kinase activity
NQ550_RS08715	COG1131	(ABC) transporter
NQ550_RS08720	COG0745	RESPONSE REGULATOR receiver
NQ550_RS08735	COG0745	RESPONSE REGULATOR receiver
NQ550_RS08740	COG5002	protein histidine kinase activity
NQ550_RS08795	COG1484	DNA-dependent DNA replication
NQ550_RS08805	COG2801	Transposase and inactivated derivatives
NQ550_RS08865	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NQ550_RS08870	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NQ550_RS08875	COG0385	Bile acid
NQ550_RS08880	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NQ550_RS08905	COG1028	Short-chain dehydrogenase reductase Sdr
NQ550_RS08940	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NQ550_RS08960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NQ550_RS08965	COG1366	Belongs to the anti-sigma-factor antagonist family
NQ550_RS08980	COG4656	Part of a membrane complex involved in electron transport
NQ550_RS08985	COG4658	electron transport chain
NQ550_RS08990	COG4659	FMN binding
NQ550_RS08995	COG4660	Part of a membrane complex involved in electron transport
NQ550_RS09000	COG4657	Part of a membrane complex involved in electron transport
NQ550_RS09005	COG1245	4Fe-4S binding domain
NQ550_RS09005	COG2878	Part of a membrane complex involved in electron transport
NQ550_RS09010	COG0632	four-way junction helicase activity
NQ550_RS09015	COG2255	four-way junction helicase activity
NQ550_RS09020	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NQ550_RS09025	COG0826	peptidase U32
NQ550_RS09035	COG0768	penicillin binding
NQ550_RS09060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQ550_RS09070	COG1461	Dihydroxyacetone kinase
NQ550_RS09075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NQ550_RS09085	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NQ550_RS09085	COG1918	ferrous iron import across plasma membrane
NQ550_RS09095	COG1803	Methylglyoxal synthase
NQ550_RS09100	COG0742	ribosomal rna small subunit methyltransferase
NQ550_RS09105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQ550_RS09120	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQ550_RS09125	COG2357	RelA SpoT domain protein
NQ550_RS09140	COG0564	pseudouridine synthase activity
NQ550_RS09150	COG3331	DNA recombination
NQ550_RS09155	COG0124	histidyl-tRNA synthetase
NQ550_RS09160	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NQ550_RS09165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NQ550_RS09170	COG0131	Imidazoleglycerol-phosphate dehydratase
NQ550_RS09200	COG1120	ATPase activity
NQ550_RS09205	COG0463	Glycosyl transferase, family 2
NQ550_RS09220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQ550_RS09225	COG0463	Glycosyl transferase, family 2
NQ550_RS09265	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
NQ550_RS09295	COG1053	succinate dehydrogenase
NQ550_RS09300	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ550_RS09300	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ550_RS09330	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NQ550_RS09345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQ550_RS09360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ550_RS09370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQ550_RS09390	COG1918	ferrous iron import across plasma membrane
NQ550_RS09390	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NQ550_RS09430	COG2217	Heavy metal translocating P-type atpase
NQ550_RS09435	COG0640	Transcriptional regulator
NQ550_RS09455	COG0348	domain, Protein
NQ550_RS09455	COG3901	Regulator of nitric oxide reductase transcription
NQ550_RS09460	COG1477	protein flavinylation
NQ550_RS09490	COG0148	phosphopyruvate hydratase activity
NQ550_RS09500	COG0372	Belongs to the citrate synthase family
NQ550_RS09510	COG0658	competence protein
NQ550_RS09510	COG2333	competence protein COMEC
NQ550_RS09525	COG0251	oxidation-reduction process
NQ550_RS09605	COG0739	heme binding
NQ550_RS09605	COG0741	lytic transglycosylase activity
NQ550_RS09605	COG1196	nuclear chromosome segregation
NQ550_RS09680	COG1278	Cold shock
NQ550_RS09725	COG4509	Sortase family
NQ550_RS09735	COG1131	(ABC) transporter
NQ550_RS09750	COG5002	protein histidine kinase activity
NQ550_RS09755	COG0745	RESPONSE REGULATOR receiver
NQ550_RS09765	COG1136	(ABC) transporter
NQ550_RS09770	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NQ550_RS09775	COG0352	thiamine-phosphate diphosphorylase activity
NQ550_RS09775	COG0351	phosphomethylpyrimidine kinase
NQ550_RS09780	COG0352	thiamine-phosphate diphosphorylase activity
NQ550_RS09785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQ550_RS09795	COG0456	acetyltransferase
NQ550_RS09800	COG0778	Nitroreductase
NQ550_RS09805	COG1733	regulation of RNA biosynthetic process
NQ550_RS09810	COG0745	RESPONSE REGULATOR receiver
NQ550_RS09825	COG2205	protein histidine kinase activity
NQ550_RS09845	COG5002	protein histidine kinase activity
NQ550_RS09850	COG0577	efflux transmembrane transporter activity
NQ550_RS09850	COG1136	(ABC) transporter
NQ550_RS09860	COG1136	(ABC) transporter
NQ550_RS09880	COG0745	RESPONSE REGULATOR receiver
NQ550_RS09885	COG2205	protein histidine kinase activity
NQ550_RS09955	COG0270	DNA (cytosine-5-)-methyltransferase activity
NQ550_RS10025	COG2003	Belongs to the UPF0758 family
NQ550_RS10045	COG0175	sulfate reduction
NQ550_RS10110	COG3279	Response regulator of the LytR AlgR family
NQ550_RS10130	COG2801	Transposase and inactivated derivatives
NQ550_RS10140	COG0535	radical SAM domain protein
NQ550_RS10145	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NQ550_RS10160	COG1132	(ABC) transporter
NQ550_RS10170	COG0577	efflux transmembrane transporter activity
NQ550_RS10170	COG1136	(ABC) transporter
NQ550_RS10180	COG0745	RESPONSE REGULATOR receiver
NQ550_RS10200	COG0439	Biotin carboxylase
NQ550_RS10205	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NQ550_RS10205	COG0825	malonyl-CoA metabolic process
NQ550_RS10215	COG3279	Response regulator of the LytR AlgR family
NQ550_RS10245	COG0534	Mate efflux family protein
NQ550_RS10265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQ550_RS10280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NQ550_RS10290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQ550_RS10295	COG0745	RESPONSE REGULATOR receiver
NQ550_RS10335	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NQ550_RS10385	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NQ550_RS10395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NQ550_RS10400	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NQ550_RS10405	COG1534	Rna-binding protein
NQ550_RS10410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQ550_RS10415	COG1713	HD superfamily hydrolase involved in NAD metabolism
NQ550_RS10420	COG0799	negative regulation of ribosome biogenesis
NQ550_RS10425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQ550_RS10435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NQ550_RS10450	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NQ550_RS10460	COG0564	pseudouridine synthase activity
NQ550_RS10470	COG0628	permease
NQ550_RS10480	COG0824	Thioesterase
NQ550_RS10490	COG4974	Belongs to the 'phage' integrase family
NQ550_RS10505	COG0582	viral genome integration into host DNA
NQ550_RS10555	COG1686	Belongs to the peptidase S11 family
NQ550_RS10565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NQ550_RS10570	COG2894	cell division
NQ550_RS10575	COG0768	penicillin binding
NQ550_RS10590	COG1077	Cell shape determining protein MreB Mrl
NQ550_RS10595	COG2003	Belongs to the UPF0758 family
NQ550_RS10600	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NQ550_RS10605	COG2081	HI0933 family
NQ550_RS10610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NQ550_RS10615	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NQ550_RS10625	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NQ550_RS10670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQ550_RS10700	COG1937	Protein conserved in bacteria
NQ550_RS10710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ550_RS10725	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NQ550_RS10730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NQ550_RS10735	COG4224	UPF0291 protein
NQ550_RS10740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NQ550_RS10745	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NQ550_RS10750	COG1702	phosphate starvation-inducible protein PhoH
NQ550_RS10770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NQ550_RS10785	COG1968	undecaprenyl-diphosphatase activity
NQ550_RS10790	COG1295	ribonuclease BN
NQ550_RS10805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NQ550_RS10820	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ550_RS10825	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NQ550_RS10830	COG1882	Formate acetyltransferase
NQ550_RS10835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ550_RS10865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ550_RS10870	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQ550_RS10875	COG0549	Belongs to the carbamate kinase family
NQ550_RS10885	COG3293	Transposase
NQ550_RS10890	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ550_RS10895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NQ550_RS10900	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NQ550_RS10900	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ550_RS10905	COG2080	2 iron, 2 sulfur cluster binding
NQ550_RS10910	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NQ550_RS10915	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQ550_RS10930	COG0493	'glutamate synthase
NQ550_RS10930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ550_RS10935	COG0402	S-adenosylhomocysteine deaminase activity
NQ550_RS10945	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
NQ550_RS10950	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NQ550_RS10960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NQ550_RS10965	COG2246	polysaccharide biosynthetic process
NQ550_RS10970	COG0463	Glycosyl transferase, family 2
NQ550_RS10975	COG4485	Bacterial membrane protein, YfhO
NQ550_RS10985	COG1959	2 iron, 2 sulfur cluster binding
NQ550_RS10990	COG0488	(ABC) transporter
NQ550_RS10995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NQ550_RS11035	COG1132	(ABC) transporter
NQ550_RS11040	COG1132	(ABC) transporter
NQ550_RS11040	COG2375	cellular response to nickel ion
NQ550_RS11045	COG2207	Transcriptional regulator
NQ550_RS11045	COG3708	Transcriptional regulator
NQ550_RS11055	COG0741	lytic transglycosylase activity
NQ550_RS11055	COG0791	NLP P60 protein
NQ550_RS11110	COG2946	Replication initiation factor
NQ550_RS11120	COG1674	ftsk spoiiie
NQ550_RS11145	COG4869	propanediol catabolic process
NQ550_RS11155	COG2199	diguanylate cyclase activity
NQ550_RS11160	COG0784	Response regulator, receiver
NQ550_RS11160	COG2205	protein histidine kinase activity
NQ550_RS11165	COG3711	transcriptional antiterminator
NQ550_RS11170	COG1263	PTS System
NQ550_RS11170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ550_RS11170	COG2190	(PTS) system
NQ550_RS11225	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NQ550_RS11240	COG1459	type II secretion system
NQ550_RS11250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NQ550_RS11275	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NQ550_RS11280	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQ550_RS11290	COG0726	polysaccharide deacetylase
NQ550_RS11305	COG1757	Na H antiporter
NQ550_RS11320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQ550_RS11345	COG0671	phosphoesterase, PA-phosphatase related
NQ550_RS11370	COG1454	alcohol dehydrogenase
NQ550_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
NQ550_RS11380	COG2357	RelA SpoT domain protein
NQ550_RS11415	COG2337	Toxic component of a toxin-antitoxin (TA) module
NQ550_RS11430	COG2205	protein histidine kinase activity
NQ550_RS11435	COG0745	RESPONSE REGULATOR receiver
NQ550_RS11445	COG1136	(ABC) transporter
NQ550_RS11470	COG2207	Transcriptional regulator
NQ550_RS11470	COG3708	Transcriptional regulator
NQ550_RS11480	COG0791	NLP P60 protein
NQ550_RS11480	COG0741	lytic transglycosylase activity
NQ550_RS11485	COG4509	Sortase family
NQ550_RS11610	COG1192	Involved in chromosome partitioning
NQ550_RS11620	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ550_RS11620	COG0574	Belongs to the PEP-utilizing enzyme family
NQ550_RS11635	COG1410	methionine synthase
NQ550_RS11635	COG0646	methionine synthase
NQ550_RS11650	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ550_RS11660	COG1177	transmembrane transport
NQ550_RS11670	COG3842	ATPase activity
NQ550_RS11675	COG1177	transmembrane transport
NQ550_RS11685	COG3842	ATPase activity
NQ550_RS11695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NQ550_RS11700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ550_RS11715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQ550_RS11720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NQ550_RS11725	COG0028	Belongs to the TPP enzyme family
NQ550_RS11740	COG1862	Preprotein translocase
NQ550_RS11745	COG0343	queuine tRNA-ribosyltransferase activity
NQ550_RS11765	COG0107	imidazoleglycerol-phosphate synthase activity
NQ550_RS11775	COG5002	protein histidine kinase activity
NQ550_RS11780	COG0745	RESPONSE REGULATOR receiver
NQ550_RS11800	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ550_RS11810	COG0372	Belongs to the citrate synthase family
NQ550_RS11815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQ550_RS11830	COG1191	sigma factor activity
NQ550_RS11845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NQ550_RS11845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQ550_RS11860	COG0438	transferase activity, transferring glycosyl groups
NQ550_RS11885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQ550_RS11895	COG2172	sigma factor antagonist activity
NQ550_RS11900	COG1366	Belongs to the anti-sigma-factor antagonist family
NQ550_RS11905	COG0110	maltose O-acetyltransferase activity
NQ550_RS11910	COG0534	Mate efflux family protein
NQ550_RS11930	COG0419	ATPase involved in DNA repair
NQ550_RS11940	COG1349	DNA-binding transcription factor activity
NQ550_RS11945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ550_RS11945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ550_RS11950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQ550_RS11950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQ550_RS11950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ550_RS11955	COG1105	Belongs to the carbohydrate kinase PfkB family
NQ550_RS11960	COG1115	amino acid carrier protein
NQ550_RS11975	COG1132	(ABC) transporter
NQ550_RS11980	COG1132	(ABC) transporter
NQ550_RS11985	COG0006	proline dipeptidase activity
NQ550_RS11990	COG1606	tRNA processing
NQ550_RS12000	COG2211	Major facilitator Superfamily
NQ550_RS12015	COG3620	sequence-specific DNA binding
NQ550_RS12020	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
NQ550_RS12070	COG5002	protein histidine kinase activity
NQ550_RS12070	COG0642	Histidine kinase
NQ550_RS12075	COG0745	RESPONSE REGULATOR receiver
NQ550_RS12200	COG3843	relaxase mobilization nuclease domain protein
NQ550_RS12220	COG0745	RESPONSE REGULATOR receiver
NQ550_RS12225	COG5002	protein histidine kinase activity
NQ550_RS12370	COG1475	DNA binding
NQ550_RS12375	COG1192	Involved in chromosome partitioning
NQ550_RS12390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NQ550_RS12395	COG0052	Belongs to the universal ribosomal protein uS2 family
NQ550_RS12400	COG1187	pseudouridine synthase activity
NQ550_RS12410	COG1131	(ABC) transporter
NQ550_RS12415	COG1725	Transcriptional regulator
NQ550_RS12435	COG0515	serine threonine protein kinase
NQ550_RS12435	COG2815	serine threonine protein kinase
NQ550_RS12445	COG1307	EDD domain protein, DegV family
NQ550_RS12450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ550_RS12460	COG0577	efflux transmembrane transporter activity
NQ550_RS12475	COG1136	(ABC) transporter
NQ550_RS12490	COG0730	response to heat
NQ550_RS12495	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQ550_RS12500	COG0124	histidyl-tRNA synthetase
NQ550_RS12510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQ550_RS12520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQ550_RS12525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQ550_RS12530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NQ550_RS12530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NQ550_RS12535	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQ550_RS12535	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQ550_RS12540	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ550_RS12560	COG1253	flavin adenine dinucleotide binding
NQ550_RS12570	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ550_RS12580	COG4120	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS12585	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NQ550_RS12595	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQ550_RS12625	COG2205	protein histidine kinase activity
NQ550_RS12625	COG2770	Histidine kinase
NQ550_RS12635	COG1396	sequence-specific DNA binding
NQ550_RS12645	COG3843	relaxase mobilization nuclease domain protein
NQ550_RS12665	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ550_RS12665	COG0551	DNA topoisomerase type I activity
NQ550_RS12735	COG0358	DNA primase activity
NQ550_RS12770	COG1396	sequence-specific DNA binding
NQ550_RS12775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQ550_RS12875	COG3340	Belongs to the peptidase S51 family
NQ550_RS12890	COG0582	viral genome integration into host DNA
NQ550_RS12900	COG1484	DNA-dependent DNA replication
NQ550_RS12925	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NQ550_RS12930	COG1053	succinate dehydrogenase
NQ550_RS12945	COG2217	Heavy metal translocating P-type atpase
NQ550_RS12980	COG2315	Protein conserved in bacteria
NQ550_RS12990	COG3843	relaxase mobilization nuclease domain protein
NQ550_RS12995	COG0745	RESPONSE REGULATOR receiver
NQ550_RS13000	COG0582	viral genome integration into host DNA
NQ550_RS13025	COG1136	(ABC) transporter
NQ550_RS13025	COG0577	efflux transmembrane transporter activity
NQ550_RS13065	COG1192	Involved in chromosome partitioning
NQ550_RS13085	COG0745	RESPONSE REGULATOR receiver
NQ550_RS13125	COG0768	penicillin binding
NQ550_RS13145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NQ550_RS13185	COG0582	viral genome integration into host DNA
NQ550_RS13190	COG1199	ATP-dependent helicase activity
NQ550_RS13190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NQ550_RS13230	COG2205	protein histidine kinase activity
NQ550_RS13235	COG0745	RESPONSE REGULATOR receiver
NQ550_RS13245	COG1136	(ABC) transporter
NQ550_RS13255	COG0741	lytic transglycosylase activity
NQ550_RS13255	COG0791	NLP P60 protein
NQ550_RS13345	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQ550_RS13350	COG4509	Sortase family
NQ550_RS13420	COG0583	DNA-binding transcription factor activity
NQ550_RS13440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NQ550_RS13445	COG1288	antiporter activity
NQ550_RS13450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQ550_RS13475	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NQ550_RS13480	COG3404	Formiminotransferase-cyclodeaminase
NQ550_RS13525	COG1151	hydroxylamine reductase activity
NQ550_RS13545	COG0656	L-ascorbic acid biosynthetic process
NQ550_RS13555	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NQ550_RS13570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NQ550_RS13580	COG0792	nuclease activity
NQ550_RS13585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQ550_RS13590	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NQ550_RS13600	COG0335	large ribosomal subunit rRNA binding
NQ550_RS13625	COG0072	phenylalanine-tRNA ligase activity
NQ550_RS13625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ550_RS13630	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NQ550_RS13635	COG0493	'glutamate synthase
NQ550_RS13645	COG0740	serine-type endopeptidase activity
NQ550_RS13650	COG0217	transcriptional regulatory protein
NQ550_RS13660	COG2337	Toxic component of a toxin-antitoxin (TA) module
NQ550_RS13670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NQ550_RS13670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NQ550_RS13675	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NQ550_RS13680	COG0488	(ABC) transporter
NQ550_RS13690	COG1404	Belongs to the peptidase S8 family
NQ550_RS13710	COG2315	Protein conserved in bacteria
NQ550_RS13750	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NQ550_RS13790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NQ550_RS13810	COG0534	Mate efflux family protein
NQ550_RS13835	COG0300	oxidoreductase activity
NQ550_RS13925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NQ550_RS13935	COG0564	pseudouridine synthase activity
NQ550_RS13945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQ550_RS13945	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQ550_RS13960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQ550_RS13980	COG3547	Transposase (IS116 IS110 IS902 family)
NQ550_RS13990	COG5426	von Willebrand factor, type A
NQ550_RS14010	COG0395	ABC-type sugar transport system, permease component
NQ550_RS14055	COG0745	RESPONSE REGULATOR receiver
NQ550_RS14065	COG1216	Glycosyl transferase, family 2
NQ550_RS14080	COG1194	a g-specific adenine glycosylase
NQ550_RS14095	COG0534	Mate efflux family protein
NQ550_RS14100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NQ550_RS14105	COG0460	homoserine dehydrogenase
NQ550_RS14130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQ550_RS14135	COG0149	triose-phosphate isomerase activity
NQ550_RS14150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQ550_RS14160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NQ550_RS14165	COG0822	iron-sulfur transferase activity
NQ550_RS14180	COG2244	polysaccharide biosynthetic process
NQ550_RS14185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQ550_RS14190	COG4974	Belongs to the 'phage' integrase family
NQ550_RS14200	COG1418	mRNA catabolic process
NQ550_RS14205	COG2137	regulation of response to DNA damage stimulus
NQ550_RS14210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NQ550_RS14215	COG0297	glycogen (starch) synthase activity
NQ550_RS14220	COG0745	RESPONSE REGULATOR receiver
NQ550_RS14225	COG0750	zinc metalloprotease
NQ550_RS14230	COG0497	DNA recombination
NQ550_RS14235	COG1438	arginine binding
NQ550_RS14240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQ550_RS14245	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NQ550_RS14250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ550_RS14265	COG1570	exodeoxyribonuclease VII activity
NQ550_RS14270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ550_RS14275	COG1302	Protein conserved in bacteria
NQ550_RS14280	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NQ550_RS14320	COG3854	ATPases associated with a variety of cellular activities
NQ550_RS14335	COG0210	DNA helicase
NQ550_RS14340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQ550_RS14350	COG0439	Biotin carboxylase
NQ550_RS14355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NQ550_RS14365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NQ550_RS14375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQ550_RS14385	COG0772	Belongs to the SEDS family
NQ550_RS14405	COG1234	tRNA 3'-trailer cleavage
NQ550_RS14485	COG0569	domain protein
NQ550_RS14500	COG1191	sigma factor activity
NQ550_RS14510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQ550_RS14520	COG0653	protein targeting
NQ550_RS14530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQ550_RS14545	COG1126	abc transporter atp-binding protein
NQ550_RS14550	COG0765	amino acid transport
NQ550_RS14580	COG0534	Mate efflux family protein
NQ550_RS14585	COG2070	2-Nitropropane dioxygenase
NQ550_RS14590	COG5002	protein histidine kinase activity
NQ550_RS14590	COG0784	Response regulator, receiver
NQ550_RS14615	COG1151	hydroxylamine reductase activity
NQ550_RS14620	COG2207	Transcriptional regulator
NQ550_RS14660	COG0534	Mate efflux family protein
NQ550_RS14720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NQ550_RS14725	COG1418	mRNA catabolic process
NQ550_RS14740	COG0826	peptidase U32
NQ550_RS14745	COG4122	O-methyltransferase activity
NQ550_RS14760	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NQ550_RS14775	COG4472	Bacterial protein of unknown function (DUF965)
NQ550_RS14780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ550_RS14795	COG1104	cysteine desulfurase activity
NQ550_RS14800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NQ550_RS14815	COG0484	heat shock protein binding
NQ550_RS14820	COG0443	Heat shock 70 kDa protein
NQ550_RS14825	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQ550_RS14830	COG1420	regulation of RNA biosynthetic process
NQ550_RS14840	COG0784	Response regulator, receiver
NQ550_RS14840	COG2205	protein histidine kinase activity
NQ550_RS14845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ550_RS14850	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ550_RS14855	COG0471	metal ion transport
NQ550_RS14860	COG0583	DNA-binding transcription factor activity
NQ550_RS14900	COG0431	NADPH-dependent FMN reductase
NQ550_RS14910	COG4085	toxin activity
NQ550_RS14910	COG1525	nuclease
NQ550_RS14910	COG0737	Belongs to the 5'-nucleotidase family
NQ550_RS14920	COG0793	Belongs to the peptidase S41A family
NQ550_RS14925	COG2177	Part of the ABC transporter FtsEX involved in
NQ550_RS14930	COG2884	Cell division ATP-binding protein ftsE
NQ550_RS14935	COG2508	Transcriptional regulator
NQ550_RS14940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ550_RS14950	COG1297	OPT oligopeptide transporter protein
NQ550_RS14980	COG0561	phosphatase activity
NQ550_RS14985	COG0159	tryptophan synthase activity
NQ550_RS15000	COG0134	indole-3-glycerol-phosphate synthase activity
NQ550_RS15005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NQ550_RS15010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NQ550_RS15010	COG0512	Glutamine amidotransferase of anthranilate synthase
NQ550_RS15060	COG1464	Belongs to the NlpA lipoprotein family
NQ550_RS15065	COG2011	ABC-type metal ion transport system permease component
NQ550_RS15070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQ550_RS15090	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQ550_RS15105	COG1937	Protein conserved in bacteria
NQ550_RS15115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQ550_RS15130	COG3442	glutamine amidotransferase
NQ550_RS15145	COG0203	ribosomal protein L17
NQ550_RS15150	COG0202	RNA polymerase activity
NQ550_RS15155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQ550_RS15160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NQ550_RS15170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NQ550_RS15175	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NQ550_RS15195	COG0200	Binds to the 23S rRNA
NQ550_RS15200	COG1841	ribosomal large subunit assembly
NQ550_RS15205	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQ550_RS15210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NQ550_RS15215	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NQ550_RS15220	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQ550_RS15225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NQ550_RS15245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQ550_RS15250	COG0255	Belongs to the universal ribosomal protein uL29 family
NQ550_RS15255	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NQ550_RS15265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NQ550_RS15275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NQ550_RS15285	COG0088	Forms part of the polypeptide exit tunnel
NQ550_RS15290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQ550_RS15295	COG0051	transcription antitermination factor activity, RNA binding
NQ550_RS15305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ550_RS15310	COG1481	regulation of sporulation
NQ550_RS15320	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQ550_RS15340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQ550_RS15370	COG1366	Belongs to the anti-sigma-factor antagonist family
NQ550_RS15385	COG0285	dihydrofolate synthase activity
NQ550_RS15395	COG0525	valine-tRNA ligase activity
NQ550_RS15410	COG1136	(ABC) transporter
NQ550_RS15480	COG1476	TRANSCRIPTIONal
NQ550_RS15530	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQ550_RS15530	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NQ550_RS15535	COG1074	ATP-dependent DNA helicase activity
NQ550_RS15540	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NQ550_RS15555	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NQ550_RS15560	COG2226	methyltransferase
NQ550_RS15570	COG3973	AAA domain
NQ550_RS15575	COG1132	(ABC) transporter
NQ550_RS15595	COG0733	neurotransmitter:sodium symporter activity
NQ550_RS15615	COG0542	response to heat
NQ550_RS15625	COG4974	Belongs to the 'phage' integrase family
NQ550_RS15630	COG4974	Belongs to the 'phage' integrase family
NQ550_RS15645	COG0778	Nitroreductase
NQ550_RS15650	COG1733	regulation of RNA biosynthetic process
NQ550_RS15755	COG0395	ABC-type sugar transport system, permease component
NQ550_RS15765	COG0745	RESPONSE REGULATOR receiver
NQ550_RS15770	COG2205	protein histidine kinase activity
NQ550_RS15805	COG1846	Transcriptional regulator
NQ550_RS15815	COG3300	MHYT domain
NQ550_RS15815	COG5001	Diguanylate cyclase
NQ550_RS15825	COG1132	(ABC) transporter
NQ550_RS15830	COG2375	cellular response to nickel ion
NQ550_RS15830	COG1132	(ABC) transporter
NQ550_RS15835	COG1309	transcriptional regulator
NQ550_RS15860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NQ550_RS15870	COG4106	trans-aconitate 2-methyltransferase activity
NQ550_RS15875	COG0297	glycogen (starch) synthase activity
NQ550_RS15885	COG0534	Mate efflux family protein
NQ550_RS15905	COG3547	Transposase (IS116 IS110 IS902 family)
NQ550_RS15935	COG2197	response regulator
NQ550_RS15955	COG0395	ABC-type sugar transport system, permease component
NQ550_RS15960	COG4209	transmembrane transport
NQ550_RS15965	COG1609	Transcriptional regulator
NQ550_RS15980	COG0395	ABC-type sugar transport system, permease component
NQ550_RS15985	COG1175	transmembrane transport
NQ550_RS15995	COG2972	Histidine kinase
NQ550_RS16000	COG4753	response regulator
NQ550_RS16000	COG2207	Transcriptional regulator
NQ550_RS16010	COG2200	EAL domain
NQ550_RS16045	COG0318	PFAM AMP-dependent synthetase and ligase
NQ550_RS16050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQ550_RS16065	COG5001	Diguanylate cyclase
NQ550_RS16085	COG3681	Belongs to the UPF0597 family
NQ550_RS16095	COG1611	Belongs to the LOG family
NQ550_RS16100	COG1122	ATPase activity
NQ550_RS16110	COG0310	cobalt ion transport
NQ550_RS16130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ550_RS16135	COG0601	transmembrane transport
NQ550_RS16140	COG0583	DNA-binding transcription factor activity
NQ550_RS16145	COG5001	Diguanylate cyclase
NQ550_RS16145	COG3300	MHYT domain
NQ550_RS16150	COG2239	Acts as a magnesium transporter
NQ550_RS16160	COG1760	l-serine dehydratase
NQ550_RS16200	COG0028	Belongs to the TPP enzyme family
NQ550_RS16205	COG0440	acetolactate synthase activity
NQ550_RS16210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ550_RS16230	COG4989	oxidoreductase activity
NQ550_RS16275	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS16280	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS16285	COG1129	ABC transporter
NQ550_RS16290	COG2207	Transcriptional regulator
NQ550_RS16290	COG4753	response regulator
NQ550_RS16295	COG2972	Histidine kinase
NQ550_RS16325	COG3191	aminopeptidase activity
NQ550_RS16340	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NQ550_RS16365	COG0366	Alpha amylase catalytic
NQ550_RS16380	COG0426	domain, Protein
NQ550_RS16385	COG1473	amidohydrolase
NQ550_RS16390	COG0514	ATP-dependent DNA helicase (RecQ)
NQ550_RS16410	COG2205	protein histidine kinase activity
NQ550_RS16410	COG2198	Histidine kinase
NQ550_RS16410	COG0784	Response regulator, receiver
NQ550_RS16420	COG0534	Mate efflux family protein
NQ550_RS16475	COG1937	Protein conserved in bacteria
NQ550_RS16495	COG2217	Heavy metal translocating P-type atpase
NQ550_RS16505	COG0640	Transcriptional regulator
NQ550_RS16515	COG1733	regulation of RNA biosynthetic process
NQ550_RS16535	COG0488	(ABC) transporter
NQ550_RS16565	COG1131	(ABC) transporter
NQ550_RS16585	COG1131	(ABC) transporter
NQ550_RS16590	COG0745	RESPONSE REGULATOR receiver
NQ550_RS16610	COG2207	Transcriptional regulator
NQ550_RS16610	COG3708	Transcriptional regulator
NQ550_RS16660	COG1011	Hydrolase
NQ550_RS16695	COG0395	ABC-type sugar transport system, permease component
NQ550_RS16705	COG1653	transport
NQ550_RS16710	COG2207	Transcriptional regulator
NQ550_RS16710	COG4753	response regulator
NQ550_RS16730	COG0395	ABC-type sugar transport system, permease component
NQ550_RS16735	COG1175	transmembrane transport
NQ550_RS16745	COG2207	Transcriptional regulator
NQ550_RS16755	COG0667	Aldo Keto reductase
NQ550_RS16760	COG3250	beta-galactosidase activity
NQ550_RS16765	COG4496	protein, YerC YecD
NQ550_RS16770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQ550_RS16775	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS16785	COG4213	ABC transporter substrate-binding protein
NQ550_RS16790	COG4213	ABC transporter substrate-binding protein
NQ550_RS16795	COG4753	response regulator
NQ550_RS16795	COG2207	Transcriptional regulator
NQ550_RS16800	COG2972	Histidine kinase
NQ550_RS16810	COG0726	polysaccharide deacetylase
NQ550_RS16820	COG1242	4 iron, 4 sulfur cluster binding
NQ550_RS16830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NQ550_RS16865	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NQ550_RS16875	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NQ550_RS16910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NQ550_RS16920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NQ550_RS16930	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NQ550_RS16940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQ550_RS16945	COG0772	Belongs to the SEDS family
NQ550_RS16950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NQ550_RS16955	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQ550_RS16960	COG0768	penicillin binding
NQ550_RS16965	COG0768	penicillin binding
NQ550_RS16975	COG0275	rRNA processing
NQ550_RS16980	COG2001	Belongs to the MraZ family
NQ550_RS16985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NQ550_RS16990	COG0012	GTP binding
NQ550_RS17005	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ550_RS17010	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ550_RS17045	COG1959	2 iron, 2 sulfur cluster binding
NQ550_RS17050	COG1564	THIamine pyrophosphokinase
NQ550_RS17055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NQ550_RS17065	COG2815	serine threonine protein kinase
NQ550_RS17065	COG0515	serine threonine protein kinase
NQ550_RS17070	COG0631	protein serine/threonine phosphatase activity
NQ550_RS17075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ550_RS17080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQ550_RS17080	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ550_RS17085	COG2738	Putative neutral zinc metallopeptidase
NQ550_RS17100	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQ550_RS17115	COG0549	Belongs to the carbamate kinase family
NQ550_RS17120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQ550_RS17120	COG1328	CTP reductase activity
NQ550_RS17135	COG2502	aspartate--ammonia ligase
NQ550_RS17145	COG0385	Bile acid
NQ550_RS17150	COG1126	abc transporter atp-binding protein
NQ550_RS17155	COG0765	amino acid transport
NQ550_RS17160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ550_RS17165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NQ550_RS17200	COG0482	sulfurtransferase activity
NQ550_RS17210	COG1959	2 iron, 2 sulfur cluster binding
NQ550_RS17220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQ550_RS17220	COG1328	CTP reductase activity
NQ550_RS17225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQ550_RS17235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQ550_RS17250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NQ550_RS17255	COG2890	protein-(glutamine-N5) methyltransferase activity
NQ550_RS17260	COG3872	metal-dependent enzyme
NQ550_RS17265	COG0254	rRNA binding
NQ550_RS17285	COG1459	type II secretion system
NQ550_RS17320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ550_RS17325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQ550_RS17330	COG3459	Glycosyltransferase 36 associated
NQ550_RS17335	COG1609	Transcriptional regulator
NQ550_RS17350	COG0395	ABC-type sugar transport system, permease component
NQ550_RS17360	COG0367	asparagine synthase
NQ550_RS17370	COG0367	asparagine synthase
NQ550_RS17385	COG0562	UDP-galactopyranose mutase
NQ550_RS17400	COG1216	Glycosyl transferase, family 2
NQ550_RS17415	COG1216	Glycosyl transferase, family 2
NQ550_RS17425	COG1216	Glycosyl transferase, family 2
NQ550_RS17425	COG1442	glycosyl transferase family 8
NQ550_RS17430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQ550_RS17435	COG0110	maltose O-acetyltransferase activity
NQ550_RS17455	COG0582	viral genome integration into host DNA
NQ550_RS17470	COG0646	methionine synthase
NQ550_RS17470	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NQ550_RS17480	COG4656	Part of a membrane complex involved in electron transport
NQ550_RS17500	COG1489	DNA binding
NQ550_RS17625	COG3843	relaxase mobilization nuclease domain protein
NQ550_RS17645	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ550_RS17705	COG1725	Transcriptional regulator
NQ550_RS17710	COG1131	(ABC) transporter
NQ550_RS17725	COG1404	Belongs to the peptidase S8 family
NQ550_RS17735	COG0583	DNA-binding transcription factor activity
NQ550_RS17745	COG1966	Carbon starvation protein
NQ550_RS17780	COG2390	Transcriptional regulator
NQ550_RS17830	COG1268	BioY protein
NQ550_RS17835	COG4753	response regulator
NQ550_RS17835	COG2207	Transcriptional regulator
NQ550_RS17840	COG3275	phosphorelay sensor kinase activity
NQ550_RS17845	COG0395	ABC-type sugar transport system, permease component
NQ550_RS17850	COG1175	transmembrane transport
NQ550_RS17860	COG0673	inositol 2-dehydrogenase activity
NQ550_RS17885	COG2211	Major facilitator Superfamily
NQ550_RS17890	COG1063	alcohol dehydrogenase
NQ550_RS17900	COG0534	Mate efflux family protein
NQ550_RS17935	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NQ550_RS17975	COG0582	viral genome integration into host DNA
NQ550_RS18015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQ550_RS18020	COG0583	DNA-binding transcription factor activity
NQ550_RS18025	COG3706	GGDEF domain
NQ550_RS18025	COG4251	negative regulation of phosphorylation
NQ550_RS18025	COG5001	Diguanylate cyclase
NQ550_RS18025	COG2203	Gaf domain
NQ550_RS18035	COG1131	(ABC) transporter
NQ550_RS18065	COG1349	DNA-binding transcription factor activity
NQ550_RS18070	COG4608	Belongs to the ABC transporter superfamily
NQ550_RS18075	COG0444	Belongs to the ABC transporter superfamily
NQ550_RS18090	COG0747	negative chemotaxis
NQ550_RS18095	COG0668	transmembrane transport
NQ550_RS18115	COG2183	response to ionizing radiation
NQ550_RS18120	COG2234	aminopeptidase activity
NQ550_RS18135	COG0460	homoserine dehydrogenase
NQ550_RS18140	COG4492	Belongs to the UPF0735 family
NQ550_RS18150	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NQ550_RS18160	COG0733	neurotransmitter:sodium symporter activity
NQ550_RS18165	COG0653	protein targeting
NQ550_RS18190	COG1686	Belongs to the peptidase S11 family
NQ550_RS18195	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NQ550_RS18200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ550_RS18215	COG1217	gtp-binding protein TYPA
NQ550_RS18220	COG1454	alcohol dehydrogenase
NQ550_RS18220	COG1012	belongs to the aldehyde dehydrogenase family
NQ550_RS18225	COG3347	Dehydrogenase
NQ550_RS18225	COG1028	Short-chain dehydrogenase reductase Sdr
NQ550_RS18230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQ550_RS18255	COG0246	Mannitol dehydrogenase
NQ550_RS18275	COG1283	sodium-dependent phosphate transmembrane transporter activity
NQ550_RS18280	COG1070	Carbohydrate kinase
NQ550_RS18285	COG0436	Aminotransferase
NQ550_RS18295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NQ550_RS18300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NQ550_RS18305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQ550_RS18310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NQ550_RS18315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ550_RS18320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NQ550_RS18330	COG0356	it plays a direct role in the translocation of protons across the membrane
NQ550_RS18350	COG0564	pseudouridine synthase activity
NQ550_RS18355	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQ550_RS18370	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQ550_RS18375	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQ550_RS18385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ550_RS18410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ550_RS18415	COG0116	Belongs to the methyltransferase superfamily
NQ550_RS18415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NQ550_RS18420	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS18425	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ550_RS18435	COG1879	ABC-type sugar transport system periplasmic component
NQ550_RS18440	COG2972	Histidine kinase
NQ550_RS18445	COG2207	Transcriptional regulator
NQ550_RS18445	COG4753	response regulator
NQ550_RS18465	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ550_RS18470	COG0395	ABC-type sugar transport system, permease component
NQ550_RS18475	COG4209	transmembrane transport
NQ550_RS18480	COG1653	transport
NQ550_RS18490	COG2207	Transcriptional regulator
NQ550_RS18490	COG2207	Transcriptional regulator
NQ550_RS18490	COG4753	response regulator
NQ550_RS18490	COG4753	response regulator
NQ550_RS18495	COG5002	protein histidine kinase activity
NQ550_RS18500	COG0704	Plays a role in the regulation of phosphate uptake
NQ550_RS18505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQ550_RS18510	COG0581	inorganic phosphate transmembrane transporter activity
NQ550_RS18515	COG0573	inorganic phosphate transmembrane transporter activity
NQ550_RS18535	COG1393	Belongs to the ArsC family
NQ550_RS18545	COG2205	protein histidine kinase activity
NQ550_RS18550	COG1136	(ABC) transporter
NQ550_RS18560	COG0829	nickel cation binding
NQ550_RS18570	COG0830	nickel cation binding
NQ550_RS18575	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NQ550_RS18585	COG0804	urea catabolic process
NQ550_RS18595	COG0831	urea catabolic process
NQ550_RS18600	COG1126	abc transporter atp-binding protein
NQ550_RS18605	COG0765	amino acid transport
NQ550_RS18610	COG1082	Xylose isomerase domain protein TIM barrel
NQ550_RS18615	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NQ550_RS18625	COG2222	sugar isomerase
NQ550_RS18630	COG1288	antiporter activity
NQ550_RS18635	COG0804	urea catabolic process
NQ550_RS18640	COG2188	Transcriptional regulator
NQ550_RS18655	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NQ550_RS18670	COG0534	Mate efflux family protein
NQ550_RS18685	COG0395	ABC-type sugar transport system, permease component
NQ550_RS18690	COG1175	transmembrane transport
NQ550_RS18700	COG1621	beta-fructofuranosidase activity
NQ550_RS18705	COG1609	Transcriptional regulator
NQ550_RS18720	COG0534	Mate efflux family protein
NQ550_RS18730	COG0393	Putative heavy-metal-binding
NQ550_RS18740	COG1757	Na H antiporter
NQ550_RS18745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ550_RS18755	COG1595	DNA-templated transcription, initiation
NQ550_RS18765	COG2723	6-phospho-beta-galactosidase activity
NQ550_RS18770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ550_RS18770	COG1263	PTS System
NQ550_RS18770	COG2190	(PTS) system
NQ550_RS18815	COG3547	Transposase (IS116 IS110 IS902 family)
NQ550_RS18820	COG1653	transport
NQ550_RS18825	COG1175	transmembrane transport
NQ550_RS18830	COG0395	ABC-type sugar transport system, permease component
NQ550_RS18845	COG4565	transcriptional regulatory protein
NQ550_RS18865	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQ550_RS18870	COG1051	belongs to the nudix hydrolase family
NQ550_RS18885	COG4555	ABC transporter
NQ550_RS18890	COG0789	Transcriptional regulator
NQ550_RS18895	COG3620	sequence-specific DNA binding
NQ550_RS18930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQ550_RS18935	COG0049	tRNA binding
NQ550_RS18940	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NQ550_RS18975	COG2815	serine threonine protein kinase
NQ550_RS18975	COG0515	serine threonine protein kinase
NQ550_RS18980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NQ550_RS18985	COG0085	RNA polymerase activity
NQ550_RS18995	COG0222	ribosome binding
NQ550_RS19005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NQ550_RS19050	COG0529	Catalyzes the synthesis of activated sulfate
NQ550_RS19050	COG2895	sulfate adenylyltransferase (ATP) activity
NQ550_RS19055	COG0175	sulfate reduction
NQ550_RS19070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NQ550_RS19075	COG4208	sulfate ABC transporter
NQ550_RS19080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NQ550_RS19085	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NQ550_RS19115	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NQ550_RS19130	COG1929	Belongs to the glycerate kinase type-1 family
NQ550_RS19145	COG0395	ABC-type sugar transport system, permease component
NQ550_RS19150	COG1175	transmembrane transport
NQ550_RS19165	COG4753	response regulator
NQ550_RS19165	COG2207	Transcriptional regulator
NQ550_RS19170	COG2972	Histidine kinase
NQ550_RS19190	COG1301	dicarboxylic acid transport
NQ550_RS19200	COG0395	ABC-type sugar transport system, permease component
NQ550_RS19205	COG1175	transmembrane transport
NQ550_RS19215	COG2207	Transcriptional regulator
NQ550_RS19215	COG4753	response regulator
NQ550_RS19220	COG2972	Histidine kinase
NQ550_RS19240	COG0523	cobalamin synthesis protein
NQ550_RS19245	COG1132	(ABC) transporter
NQ550_RS19250	COG1132	(ABC) transporter
NQ550_RS19265	COG1363	Peptidase, m42
NQ550_RS19275	COG0494	nUDIX hydrolase
NQ550_RS19280	COG4166	transmembrane transport
NQ550_RS19285	COG4608	Belongs to the ABC transporter superfamily
NQ550_RS19290	COG0444	Belongs to the ABC transporter superfamily
NQ550_RS19295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ550_RS19300	COG0601	transmembrane transport
NQ550_RS19305	COG0166	Belongs to the GPI family
NQ550_RS19320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NQ550_RS19330	COG3118	belongs to the thioredoxin family
NQ550_RS19345	COG0492	ferredoxin-NADP+ reductase activity
NQ550_RS19370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQ550_RS19410	COG0358	DNA primase activity
NQ550_RS19440	COG1131	(ABC) transporter
NQ550_RS19465	COG2197	response regulator
NQ550_RS19500	COG4377	Putative membrane peptidase family (DUF2324)
NQ550_RS19545	COG1204	response to ionizing radiation
NQ550_RS19580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NQ550_RS19590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NQ550_RS19645	COG3620	sequence-specific DNA binding
NQ550_RS19665	COG1131	(ABC) transporter
NQ550_RS19695	COG1475	DNA binding
NQ550_RS19720	COG1674	ftsk spoiiie
NQ550_RS19725	COG2946	Replication initiation factor
NQ550_RS19765	COG0741	lytic transglycosylase activity
NQ550_RS19765	COG0791	NLP P60 protein
NQ550_RS19850	COG2801	Transposase and inactivated derivatives
NQ550_RS19890	COG0745	RESPONSE REGULATOR receiver
NQ550_RS19905	COG1396	sequence-specific DNA binding
NQ550_RS19935	COG1131	(ABC) transporter
NQ550_RS19940	COG1725	Transcriptional regulator
NQ550_RS20005	COG0358	DNA primase activity
NQ550_RS20010	COG0582	viral genome integration into host DNA
NQ550_RS20050	COG1136	(ABC) transporter
NQ550_RS20055	COG2205	protein histidine kinase activity
NQ550_RS20060	COG0745	RESPONSE REGULATOR receiver
NQ550_RS20125	COG1192	Involved in chromosome partitioning
NQ550_RS20130	COG1475	DNA binding
NQ550_RS20150	COG3617	BRO family, N-terminal domain
NQ550_RS20230	COG0551	DNA topoisomerase type I activity
NQ550_RS20230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ550_RS20240	COG0358	DNA primase activity
NQ550_RS20260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NQ550_RS20285	COG4804	nuclease activity
NQ550_RS20320	COG1136	(ABC) transporter
NQ550_RS20375	COG4474	Belongs to the UPF0398 family
NQ550_RS20385	COG0756	dUTP diphosphatase activity
NQ550_RS20415	COG4509	Sortase family
NQ550_RS20430	COG0739	heme binding
NQ550_RS20485	COG0358	DNA primase activity
NQ550_RS20550	COG1484	DNA-dependent DNA replication
NQ550_RS20615	COG1484	DNA-dependent DNA replication
NQ550_RS20675	COG1131	(ABC) transporter
NQ550_RS20685	COG1595	DNA-templated transcription, initiation
NQ550_RS20835	COG0582	viral genome integration into host DNA
NQ550_RS20850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NQ550_RS20850	COG0519	Catalyzes the synthesis of GMP from XMP
NQ550_RS20855	COG1501	Belongs to the glycosyl hydrolase 31 family
NQ550_RS20860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQ550_RS20870	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQ550_RS20885	COG1269	ATP hydrolysis coupled proton transport
NQ550_RS20905	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NQ550_RS20915	COG1394	ATPase activity, coupled to movement of substances
NQ550_RS20940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NQ550_RS20945	COG2310	stress, protein
NQ550_RS20955	COG2310	stress, protein
NQ550_RS20960	COG3853	Toxic anion resistance protein (TelA)
NQ550_RS20985	COG1846	Transcriptional regulator
NQ550_RS20990	COG2843	Capsule synthesis protein
NQ550_RS20995	COG0084	hydrolase, TatD family'
NQ550_RS21005	COG0521	Mo-molybdopterin cofactor biosynthetic process
NQ550_RS21020	COG0641	radical SAM
NQ550_RS21025	COG0583	DNA-binding transcription factor activity
NQ550_RS21035	COG2059	Chromate
NQ550_RS21045	COG3119	arylsulfatase activity
NQ550_RS21060	COG4974	Belongs to the 'phage' integrase family
NQ550_RS21080	COG1773	rubredoxin
NQ550_RS21080	COG1592	Rubrerythrin
NQ550_RS21090	COG1686	Belongs to the peptidase S11 family
NQ550_RS21095	COG0081	regulation of translation
NQ550_RS21105	COG0250	Participates in transcription elongation, termination and antitermination
NQ550_RS21115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQ550_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
NQ550_RS21125	COG0028	Belongs to the TPP enzyme family
NQ550_RS21135	COG3475	LICD family
NQ550_RS21145	COG3594	Acyltransferase
NQ550_RS21150	COG1216	Glycosyl transferase, family 2
NQ550_RS21150	COG0463	Glycosyl transferase, family 2
NQ550_RS21155	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQ550_RS21170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NQ550_RS21225	COG5012	cobalamin binding
NQ550_RS21240	COG5012	cobalamin binding
NQ550_RS21270	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NQ550_RS21280	COG0484	heat shock protein binding
NQ550_RS21285	COG0071	Belongs to the small heat shock protein (HSP20) family
NQ550_RS21320	COG4753	response regulator
NQ550_RS21320	COG2207	Transcriptional regulator
NQ550_RS21325	COG2972	Histidine kinase
NQ550_RS21330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQ550_RS21335	COG0395	ABC-type sugar transport system, permease component
NQ550_RS21345	COG2182	Extracellular solute-binding protein
NQ550_RS21350	COG4804	nuclease activity
NQ550_RS21380	COG0149	triose-phosphate isomerase activity
NQ550_RS21390	COG0191	fructose-bisphosphate aldolase activity
NQ550_RS21400	COG0363	glucosamine-6-phosphate deaminase activity
NQ550_RS21410	COG1609	Transcriptional regulator
NQ550_RS21415	COG2222	sugar isomerase
NQ550_RS21425	COG1609	Transcriptional regulator
NQ550_RS21445	COG0205	6-phosphofructokinase activity
NQ550_RS21450	COG2059	Chromate
NQ550_RS21465	COG2205	protein histidine kinase activity
NQ550_RS21465	COG0784	Response regulator, receiver
NQ550_RS21465	COG2198	Histidine kinase
NQ550_RS21490	COG1917	Cupin 2, conserved barrel domain protein
NQ550_RS21490	COG2207	Transcriptional regulator
NQ550_RS21495	COG3901	Regulator of nitric oxide reductase transcription
NQ550_RS21495	COG0348	domain, Protein
NQ550_RS21505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NQ550_RS21515	COG0745	RESPONSE REGULATOR receiver
NQ550_RS21520	COG2205	protein histidine kinase activity
NQ550_RS21550	COG0534	Mate efflux family protein
NQ550_RS21560	COG0038	chloride channel
NQ550_RS21645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQ550_RS21660	COG0436	Aminotransferase
NQ550_RS21670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ550_RS21675	COG0066	3-isopropylmalate dehydratase activity
NQ550_RS21680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ550_RS21685	COG0066	3-isopropylmalate dehydratase activity
NQ550_RS21695	COG0295	cytidine deaminase activity
NQ550_RS21700	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NQ550_RS21750	COG1131	(ABC) transporter
NQ550_RS21795	COG1192	Involved in chromosome partitioning
NQ550_RS21805	COG1475	DNA binding
NQ550_RS21825	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NQ550_RS21835	COG1475	DNA binding
NQ550_RS21840	COG1192	Involved in chromosome partitioning
NQ550_RS21870	COG0357	Ribosomal RNA small subunit methyltransferase G
NQ550_RS21875	COG0445	tRNA wobble uridine modification
NQ550_RS21880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NQ550_RS21885	COG1847	R3H domain protein
NQ550_RS21890	COG0706	membrane insertase activity
NQ550_RS21895	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NQ550_RS21900	COG0594	ribonuclease P activity