locus-tag	class	description
BOBLI757_RS00005	COG0445	tRNA wobble uridine modification
BOBLI757_RS00010	COG0356	it plays a direct role in the translocation of protons across the membrane
BOBLI757_RS00020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BOBLI757_RS00025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BOBLI757_RS00030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BOBLI757_RS00040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BOBLI757_RS00045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BOBLI757_RS00055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BOBLI757_RS00060	COG0706	membrane insertase activity
BOBLI757_RS00065	COG0594	ribonuclease P activity
BOBLI757_RS00070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BOBLI757_RS00090	COG0071	Belongs to the small heat shock protein (HSP20) family
BOBLI757_RS00105	COG0751	glycine-tRNA ligase activity
BOBLI757_RS00110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BOBLI757_RS00115	COG0339	signal peptide processing
BOBLI757_RS00120	COG0306	phosphate transporter
BOBLI757_RS00125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BOBLI757_RS00130	COG0735	belongs to the Fur family
BOBLI757_RS00145	COG0025	NhaP-type Na H and K H
BOBLI757_RS00150	COG1301	dicarboxylic acid transport
BOBLI757_RS00155	COG0251	oxidation-reduction process
BOBLI757_RS00160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOBLI757_RS00165	COG0525	valine-tRNA ligase activity
BOBLI757_RS00170	COG2927	DNA polymerase III (CHI subunit)
BOBLI757_RS00180	COG0795	lipopolysaccharide-transporting ATPase activity
BOBLI757_RS00185	COG0795	lipopolysaccharide-transporting ATPase activity
BOBLI757_RS00195	COG1121	(ABC) transporter
BOBLI757_RS00200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOBLI757_RS00205	COG1137	ATPase activity
BOBLI757_RS00210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BOBLI757_RS00220	COG5007	Belongs to the BolA IbaG family
BOBLI757_RS00225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BOBLI757_RS00230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOBLI757_RS00240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BOBLI757_RS00245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BOBLI757_RS00255	COG2823	Periplasmic or secreted lipoprotein
BOBLI757_RS00260	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BOBLI757_RS00265	COG0586	Pfam SNARE associated Golgi protein
BOBLI757_RS00280	COG0358	DNA primase activity
BOBLI757_RS00290	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BOBLI757_RS00295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BOBLI757_RS00300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BOBLI757_RS00305	COG1968	undecaprenyl-diphosphatase activity
BOBLI757_RS00310	COG0617	tRNA 3'-terminal CCA addition
BOBLI757_RS00320	COG0204	Acyl-transferase
BOBLI757_RS00340	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BOBLI757_RS00345	COG0459	protein refolding
BOBLI757_RS00350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BOBLI757_RS00355	COG1511	domain protein
BOBLI757_RS00355	COG3264	Mechanosensitive ion channel
BOBLI757_RS00360	COG0688	phosphatidylethanolamine metabolic process
BOBLI757_RS00370	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BOBLI757_RS00380	COG0802	atpase or kinase
BOBLI757_RS00390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BOBLI757_RS00395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BOBLI757_RS00400	COG0330	HflC and HflK could
BOBLI757_RS00405	COG0330	HflC and HflK could
BOBLI757_RS00410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BOBLI757_RS00415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOBLI757_RS00420	COG0360	Binds together with S18 to 16S ribosomal RNA
BOBLI757_RS00425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BOBLI757_RS00430	COG0359	binds to the 23S rRNA
BOBLI757_RS00435	COG1218	3'(2'),5'-bisphosphate nucleotidase
BOBLI757_RS00440	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BOBLI757_RS00445	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BOBLI757_RS00450	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BOBLI757_RS00455	COG0142	geranyltranstransferase activity
BOBLI757_RS00470	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BOBLI757_RS00480	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BOBLI757_RS00485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BOBLI757_RS00490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BOBLI757_RS00505	COG0779	Required for maturation of 30S ribosomal subunits
BOBLI757_RS00510	COG0195	Participates in both transcription termination and antitermination
BOBLI757_RS00515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BOBLI757_RS00520	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BOBLI757_RS00525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BOBLI757_RS00530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BOBLI757_RS00535	COG1185	polyribonucleotide nucleotidyltransferase activity
BOBLI757_RS00540	COG0513	Belongs to the DEAD box helicase family
BOBLI757_RS00555	COG0083	homoserine kinase activity
BOBLI757_RS00565	COG0443	Heat shock 70 kDa protein
BOBLI757_RS00570	COG0484	heat shock protein binding
BOBLI757_RS00575	COG0268	Binds directly to 16S ribosomal RNA
BOBLI757_RS00580	COG0196	riboflavin kinase activity
BOBLI757_RS00585	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BOBLI757_RS00590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BOBLI757_RS00600	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BOBLI757_RS00605	COG0505	Belongs to the CarA family
BOBLI757_RS00610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BOBLI757_RS00620	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BOBLI757_RS00630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOBLI757_RS00635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BOBLI757_RS00640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOBLI757_RS00645	COG0473	3-isopropylmalate dehydrogenase activity
BOBLI757_RS00650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BOBLI757_RS00655	COG0066	3-isopropylmalate dehydratase activity
BOBLI757_RS00660	COG0275	rRNA processing
BOBLI757_RS00665	COG3116	cell division
BOBLI757_RS00670	COG0768	penicillin binding
BOBLI757_RS00675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BOBLI757_RS00680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BOBLI757_RS00685	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BOBLI757_RS00690	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BOBLI757_RS00695	COG0772	Belongs to the SEDS family
BOBLI757_RS00705	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BOBLI757_RS00715	COG0849	cell division
BOBLI757_RS00725	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BOBLI757_RS00730	COG0653	protein targeting
BOBLI757_RS00735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BOBLI757_RS00740	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOBLI757_RS00745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOBLI757_RS00750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BOBLI757_RS00760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOBLI757_RS00770	COG0316	Belongs to the HesB IscA family
BOBLI757_RS00775	COG0504	CTP synthase activity
BOBLI757_RS00780	COG0148	phosphopyruvate hydratase activity
BOBLI757_RS00785	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BOBLI757_RS00790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOBLI757_RS00795	COG0175	sulfate reduction
BOBLI757_RS00800	COG1648	precorrin-2 dehydrogenase activity
BOBLI757_RS00800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOBLI757_RS00810	COG2895	sulfate adenylyltransferase (ATP) activity
BOBLI757_RS00825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BOBLI757_RS00830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BOBLI757_RS00840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOBLI757_RS00845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BOBLI757_RS00860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BOBLI757_RS00875	COG0336	Belongs to the RNA methyltransferase TrmD family
BOBLI757_RS00880	COG0335	large ribosomal subunit rRNA binding
BOBLI757_RS00885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOBLI757_RS00890	COG1605	Chorismate mutase
BOBLI757_RS00890	COG0287	Prephenate dehydrogenase
BOBLI757_RS00895	COG0077	Prephenate dehydratase
BOBLI757_RS00895	COG1605	Chorismate mutase
BOBLI757_RS00900	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOBLI757_RS00905	COG0564	pseudouridine synthase activity
BOBLI757_RS00910	COG0542	response to heat
BOBLI757_RS00915	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BOBLI757_RS00955	COG0088	Forms part of the polypeptide exit tunnel
BOBLI757_RS00960	COG0089	rRNA binding
BOBLI757_RS00965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BOBLI757_RS00970	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BOBLI757_RS00975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BOBLI757_RS00980	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BOBLI757_RS00985	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BOBLI757_RS00990	COG0255	Belongs to the universal ribosomal protein uL29 family
BOBLI757_RS00995	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BOBLI757_RS01000	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BOBLI757_RS01010	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BOBLI757_RS01015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BOBLI757_RS01020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BOBLI757_RS01025	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BOBLI757_RS01035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BOBLI757_RS01040	COG1841	ribosomal large subunit assembly
BOBLI757_RS01045	COG0200	Binds to the 23S rRNA
BOBLI757_RS01050	COG0201	protein transport
BOBLI757_RS01055	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BOBLI757_RS01060	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BOBLI757_RS01065	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BOBLI757_RS01070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BOBLI757_RS01080	COG0203	ribosomal protein L17
BOBLI757_RS01085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BOBLI757_RS01090	COG0242	peptide deformylase activity
BOBLI757_RS01095	COG0009	L-threonylcarbamoyladenylate synthase
BOBLI757_RS01100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BOBLI757_RS01110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOBLI757_RS01115	COG2226	methyltransferase
BOBLI757_RS01120	COG0328	RNA-DNA hybrid ribonuclease activity
BOBLI757_RS01130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BOBLI757_RS01140	COG0450	alkyl hydroperoxide reductase
BOBLI757_RS01145	COG1862	Preprotein translocase
BOBLI757_RS01180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOBLI757_RS01185	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BOBLI757_RS01190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BOBLI757_RS01200	COG0301	tRNA thio-modification
BOBLI757_RS01200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOBLI757_RS01205	COG2814	Major facilitator Superfamily
BOBLI757_RS01210	COG0109	protoheme IX farnesyltransferase activity
BOBLI757_RS01215	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BOBLI757_RS01220	COG1845	cytochrome c oxidase, subunit III
BOBLI757_RS01225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOBLI757_RS01230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BOBLI757_RS01235	COG0740	serine-type endopeptidase activity
BOBLI757_RS01240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BOBLI757_RS01250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BOBLI757_RS01255	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BOBLI757_RS01260	COG1678	Uncharacterized ACR, COG1678
BOBLI757_RS01265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BOBLI757_RS01270	COG0010	Belongs to the arginase family
BOBLI757_RS01275	COG0126	phosphoglycerate kinase activity
BOBLI757_RS01285	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BOBLI757_RS01290	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BOBLI757_RS01295	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BOBLI757_RS01300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOBLI757_RS01310	COG0354	folic acid binding
BOBLI757_RS01315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BOBLI757_RS01320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BOBLI757_RS01330	COG0667	Aldo Keto reductase
BOBLI757_RS01335	COG1051	belongs to the nudix hydrolase family
BOBLI757_RS01340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BOBLI757_RS01345	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BOBLI757_RS01350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BOBLI757_RS01355	COG1074	ATP-dependent DNA helicase activity
BOBLI757_RS01360	COG2171	N-acyltransferase activity
BOBLI757_RS01365	COG0024	Methionine aminopeptidase
BOBLI757_RS01375	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BOBLI757_RS01380	COG0528	UMP kinase activity
BOBLI757_RS01385	COG0233	cytoplasmic translational termination
BOBLI757_RS01395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BOBLI757_RS01400	COG0575	Belongs to the CDS family
BOBLI757_RS01405	COG0750	zinc metalloprotease
BOBLI757_RS01410	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOBLI757_RS01415	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BOBLI757_RS01420	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOBLI757_RS01425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOBLI757_RS01430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOBLI757_RS01435	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOBLI757_RS01440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BOBLI757_RS01445	COG0587	DNA-directed DNA polymerase activity
BOBLI757_RS01450	COG0825	malonyl-CoA metabolic process
BOBLI757_RS01455	COG0037	tRNA processing
BOBLI757_RS01460	COG0442	prolyl-tRNA aminoacylation
BOBLI757_RS01470	COG1792	Involved in formation and maintenance of cell shape
BOBLI757_RS01475	COG1077	Cell shape determining protein MreB Mrl
BOBLI757_RS01480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BOBLI757_RS01485	COG0511	ligase activity, forming carbon-carbon bonds
BOBLI757_RS01490	COG0439	Biotin carboxylase
BOBLI757_RS01495	COG0312	modulator of DNA gyrase
BOBLI757_RS01500	COG0312	modulator of DNA gyrase
BOBLI757_RS01505	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BOBLI757_RS01510	COG0776	regulation of translation
BOBLI757_RS01525	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BOBLI757_RS01535	COG0563	adenylate kinase activity
BOBLI757_RS01540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOBLI757_RS01545	COG0215	cysteine-tRNA ligase activity
BOBLI757_RS01550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BOBLI757_RS01560	COG0697	spore germination
BOBLI757_RS01565	COG0772	Belongs to the SEDS family
BOBLI757_RS01570	COG0768	penicillin binding
BOBLI757_RS01575	COG0799	negative regulation of ribosome biogenesis
BOBLI757_RS01580	COG1466	dna polymerase III delta subunit
BOBLI757_RS01585	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BOBLI757_RS01590	COG0495	leucyl-tRNA aminoacylation
BOBLI757_RS01595	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BOBLI757_RS01600	COG4535	Mg2 and Co2 transporter CorC
BOBLI757_RS01605	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BOBLI757_RS01610	COG1702	phosphate starvation-inducible protein PhoH
BOBLI757_RS01615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOBLI757_RS01635	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BOBLI757_RS01640	COG0363	glucosamine-6-phosphate deaminase activity
BOBLI757_RS01645	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOBLI757_RS01650	COG0716	FMN binding
BOBLI757_RS01655	COG0596	Alpha beta hydrolase
BOBLI757_RS01660	COG0033	Phosphoglucomutase
BOBLI757_RS01670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BOBLI757_RS01675	COG1053	succinate dehydrogenase
BOBLI757_RS01685	COG0567	Dehydrogenase, E1 component
BOBLI757_RS01690	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOBLI757_RS01700	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BOBLI757_RS01705	COG0811	peptide transport
BOBLI757_RS01710	COG0848	biopolymer transport protein
BOBLI757_RS01720	COG0823	Involved in the tonB-independent uptake of proteins
BOBLI757_RS01725	COG2885	chlorophyll binding
BOBLI757_RS01730	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BOBLI757_RS01735	COG0588	phosphoglycerate mutase activity
BOBLI757_RS01740	COG2706	6-phosphogluconolactonase activity
BOBLI757_RS01745	COG0670	Belongs to the BI1 family
BOBLI757_RS01750	COG0193	aminoacyl-tRNA hydrolase activity
BOBLI757_RS01755	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BOBLI757_RS01765	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BOBLI757_RS01780	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BOBLI757_RS01790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BOBLI757_RS01795	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BOBLI757_RS01800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BOBLI757_RS01810	COG0095	Lipoate-protein ligase
BOBLI757_RS01815	COG0316	Belongs to the HesB IscA family
BOBLI757_RS01820	COG0719	Fe-S assembly protein
BOBLI757_RS01825	COG0396	ATPase activity
BOBLI757_RS01830	COG0719	Fe-S assembly protein
BOBLI757_RS01835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOBLI757_RS01840	COG2166	iron-sulfur cluster assembly
BOBLI757_RS01855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BOBLI757_RS01860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BOBLI757_RS01865	COG1846	Transcriptional regulator
BOBLI757_RS01870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BOBLI757_RS01875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BOBLI757_RS01880	COG0114	fumarate hydratase activity
BOBLI757_RS01890	COG0163	prenyltransferase activity
BOBLI757_RS01900	COG1663	tetraacyldisaccharide 4'-kinase activity
BOBLI757_RS01905	COG1132	(ABC) transporter
BOBLI757_RS01910	COG0539	negative regulation of cytoplasmic translation
BOBLI757_RS01915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BOBLI757_RS01920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOBLI757_RS01930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BOBLI757_RS01935	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BOBLI757_RS01945	COG1674	ftsk spoiiie
BOBLI757_RS01950	COG0492	ferredoxin-NADP+ reductase activity
BOBLI757_RS01955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BOBLI757_RS01960	COG3710	Transcriptional regulator
BOBLI757_RS01970	COG1321	iron dependent repressor
BOBLI757_RS01975	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BOBLI757_RS01980	COG0482	sulfurtransferase activity
BOBLI757_RS01985	COG4591	ABC-type transport system involved in lipoprotein release permease component
BOBLI757_RS01990	COG1136	(ABC) transporter
BOBLI757_RS01995	COG4591	ABC-type transport system involved in lipoprotein release permease component
BOBLI757_RS02000	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BOBLI757_RS02005	COG0537	adenosine 5'-monophosphoramidase activity
BOBLI757_RS02010	COG0084	hydrolase, TatD family'
BOBLI757_RS02015	COG0470	DNA polymerase III
BOBLI757_RS02020	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BOBLI757_RS02025	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BOBLI757_RS02030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOBLI757_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
BOBLI757_RS02040	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BOBLI757_RS02045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOBLI757_RS02050	COG0416	fatty acid biosynthetic process
BOBLI757_RS02065	COG1530	ribonuclease E activity
BOBLI757_RS02070	COG1560	Kdo2-lipid A biosynthetic process
BOBLI757_RS02085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BOBLI757_RS02100	COG3785	DNA binding
BOBLI757_RS02105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOBLI757_RS02115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOBLI757_RS02120	COG1448	Aminotransferase
BOBLI757_RS02125	COG0017	Asparaginyl-tRNA synthetase
BOBLI757_RS02130	COG0583	DNA-binding transcription factor activity
BOBLI757_RS02155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BOBLI757_RS02160	COG0135	phosphoribosylanthranilate isomerase activity
BOBLI757_RS02160	COG0134	indole-3-glycerol-phosphate synthase activity
BOBLI757_RS02165	COG0133	tryptophan synthase activity
BOBLI757_RS02170	COG0159	tryptophan synthase activity
BOBLI757_RS02180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOBLI757_RS02185	COG1435	thymidine kinase activity
BOBLI757_RS02195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BOBLI757_RS02200	COG0708	Exodeoxyribonuclease III
BOBLI757_RS02205	COG0616	signal peptide processing
BOBLI757_RS02215	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BOBLI757_RS02220	COG0850	regulation of cytokinetic process
BOBLI757_RS02225	COG2894	cell division
BOBLI757_RS02230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BOBLI757_RS02240	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BOBLI757_RS02245	COG1253	flavin adenine dinucleotide binding
BOBLI757_RS02250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOBLI757_RS02250	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOBLI757_RS02255	COG3715	PTS system
BOBLI757_RS02260	COG3716	PTS system mannose fructose sorbose family IID component
BOBLI757_RS02270	COG0501	Belongs to the peptidase M48B family
BOBLI757_RS02275	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BOBLI757_RS02280	COG0739	heme binding
BOBLI757_RS02285	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BOBLI757_RS02290	COG0018	arginyl-trna synthetase
BOBLI757_RS02300	COG0477	Major facilitator Superfamily
BOBLI757_RS02320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BOBLI757_RS02320	COG0517	IMP dehydrogenase activity
BOBLI757_RS02325	COG2926	Belongs to the UPF0265 family
BOBLI757_RS02330	COG2925	Exonuclease
BOBLI757_RS02335	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BOBLI757_RS02345	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOBLI757_RS02350	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOBLI757_RS02350	COG0131	Imidazoleglycerol-phosphate dehydratase
BOBLI757_RS02355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BOBLI757_RS02360	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BOBLI757_RS02365	COG0107	imidazoleglycerol-phosphate synthase activity
BOBLI757_RS02370	COG0140	phosphoribosyl-ATP diphosphatase activity
BOBLI757_RS02370	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BOBLI757_RS02375	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BOBLI757_RS02380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOBLI757_RS02380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOBLI757_RS02385	COG0302	gtp cyclohydrolase
BOBLI757_RS02390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BOBLI757_RS02395	COG1181	Belongs to the D-alanine--D-alanine ligase family
BOBLI757_RS02410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BOBLI757_RS02415	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOBLI757_RS02420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOBLI757_RS02425	COG0633	Ferredoxin
BOBLI757_RS02430	COG1007	ATP synthesis coupled electron transport
BOBLI757_RS02435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOBLI757_RS02440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BOBLI757_RS02450	COG0839	Belongs to the complex I subunit 6 family
BOBLI757_RS02455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOBLI757_RS02460	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BOBLI757_RS02475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BOBLI757_RS02480	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOBLI757_RS02480	COG0649	NAD binding
BOBLI757_RS02490	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOBLI757_RS02495	COG0285	dihydrofolate synthase activity
BOBLI757_RS02500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BOBLI757_RS02515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOBLI757_RS02520	COG2890	protein-(glutamine-N5) methyltransferase activity
BOBLI757_RS02525	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BOBLI757_RS02530	COG1914	H( )-stimulated, divalent metal cation uptake system
BOBLI757_RS02535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOBLI757_RS02550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BOBLI757_RS02555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BOBLI757_RS02560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOBLI757_RS02565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BOBLI757_RS02575	COG4208	sulfate ABC transporter
BOBLI757_RS02580	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BOBLI757_RS02585	COG4150	thiosulfate binding
BOBLI757_RS02590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BOBLI757_RS02595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BOBLI757_RS02605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOBLI757_RS02610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BOBLI757_RS02615	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BOBLI757_RS02620	COG0830	nickel cation binding
BOBLI757_RS02625	COG0804	urea catabolic process
BOBLI757_RS02630	COG0832	Belongs to the urease beta subunit family
BOBLI757_RS02635	COG0831	urea catabolic process
BOBLI757_RS02640	COG0829	nickel cation binding
BOBLI757_RS02645	COG0519	Catalyzes the synthesis of GMP from XMP
BOBLI757_RS02645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOBLI757_RS02650	COG0516	GMP reductase activity
BOBLI757_RS02650	COG0517	IMP dehydrogenase activity
BOBLI757_RS02655	COG0579	oxidoreductase
BOBLI757_RS02660	COG1160	GTP binding
BOBLI757_RS02665	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOBLI757_RS02670	COG0124	histidyl-tRNA synthetase
BOBLI757_RS02675	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BOBLI757_RS02690	COG0105	UTP biosynthetic process
BOBLI757_RS02695	COG1104	cysteine desulfurase activity
BOBLI757_RS02715	COG0736	holo-[acyl-carrier-protein] synthase activity
BOBLI757_RS02725	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BOBLI757_RS02730	COG0571	ribonuclease III activity
BOBLI757_RS02735	COG0681	Belongs to the peptidase S26 family
BOBLI757_RS02740	COG0481	GTPase activity
BOBLI757_RS02745	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BOBLI757_RS02750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BOBLI757_RS02755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BOBLI757_RS02775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOBLI757_RS02795	COG0138	bifunctional purine biosynthesis protein purh
BOBLI757_RS02810	COG0085	RNA polymerase activity
BOBLI757_RS02815	COG0222	ribosome binding
BOBLI757_RS02820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BOBLI757_RS02830	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BOBLI757_RS02835	COG0250	Participates in transcription elongation, termination and antitermination
BOBLI757_RS02845	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BOBLI757_RS02850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BOBLI757_RS02855	COG0049	tRNA binding
BOBLI757_RS02860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BOBLI757_RS02870	COG0180	Tryptophanyl-tRNA synthetase
BOBLI757_RS02875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BOBLI757_RS02880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BOBLI757_RS02885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BOBLI757_RS02895	COG0316	Belongs to the HesB IscA family
BOBLI757_RS02895	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BOBLI757_RS02900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BOBLI757_RS02905	COG2095	MarC family integral membrane protein
BOBLI757_RS02910	COG0561	phosphatase activity
BOBLI757_RS02915	COG0598	Magnesium transport protein CorA
BOBLI757_RS02925	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BOBLI757_RS02930	COG0181	hydroxymethylbilane synthase activity
BOBLI757_RS02935	COG1587	Uroporphyrinogen-III synthase
BOBLI757_RS02955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BOBLI757_RS02960	COG3118	belongs to the thioredoxin family
BOBLI757_RS02965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BOBLI757_RS02970	COG0129	dihydroxy-acid dehydratase activity
BOBLI757_RS02975	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BOBLI757_RS02980	COG3978	acetolactate synthase activity
BOBLI757_RS03005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BOBLI757_RS03015	COG0626	cystathionine gamma-synthase activity
BOBLI757_RS03020	COG0254	rRNA binding
BOBLI757_RS03025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOBLI757_RS03035	COG0205	6-phosphofructokinase activity
BOBLI757_RS03040	COG1045	serine acetyltransferase
BOBLI757_RS03045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BOBLI757_RS03050	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BOBLI757_RS03055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BOBLI757_RS03060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOBLI757_RS03065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOBLI757_RS03070	COG0859	PFAM glycosyl transferase family 9
BOBLI757_RS03080	COG1519	Transferase
BOBLI757_RS03105	COG0756	dUTP diphosphatase activity
BOBLI757_RS03110	COG1561	YicC-like family, N-terminal region
BOBLI757_RS03120	COG0194	GDP metabolic process
BOBLI757_RS03125	COG1758	RNA polymerase activity
BOBLI757_RS03140	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BOBLI757_RS03145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BOBLI757_RS03160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BOBLI757_RS03170	COG0552	protein localization to endoplasmic reticulum
BOBLI757_RS03175	COG0742	ribosomal rna small subunit methyltransferase
BOBLI757_RS03180	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BOBLI757_RS03215	COG1674	ftsk spoiiie
BOBLI757_RS03215	COG3107	peptidoglycan biosynthetic process
BOBLI757_RS03215	COG1674	ftsk spoiiie
BOBLI757_RS03215	COG3107	peptidoglycan biosynthetic process
BOBLI757_RS03230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase