locus_tag old_locus_tag gene Name start end strand product note type ID NCBI BOBLI757_RS00005 BOBLI757_001 BOBLI757_RS00005 1 1896 + hypothetical protein gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00005 BOBLI757_RS00010 BOBLI757_002 BOBLI757_RS00010 2291 3100 + ATP synthase F0F1 subunit A Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00010 BOBLI757_RS00015 BOBLI757_003 BOBLI757_RS00015 3158 3397 + ATP F0F1 synthase subunit C Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00015 BOBLI757_RS00020 BOBLI757_004 BOBLI757_RS00020 3503 3973 + hypothetical protein gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00020 BOBLI757_RS00025 BOBLI757_005 BOBLI757_RS00025 4006 4539 + hypothetical protein gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00025 BOBLI757_RS00030 BOBLI757_006 BOBLI757_RS00030 4559 6100 + ATP F0F1 synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00030 BOBLI757_RS00035 BOBLI757_007 BOBLI757_RS00035 6175 7038 + ATP F0F1 synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00035 BOBLI757_RS00040 BOBLI757_008 BOBLI757_RS00040 7074 8456 + ATP synthase F0F1 subunit beta gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00040 BOBLI757_RS00045 BOBLI757_009 atpC atpC 8510 8944 + ATP synthase F0F1 subunit epsilon part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00045 BOBLI757_RS00050 BOBLI757_010 glmU glmU 9020 10387 + bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00050 BOBLI757_RS00055 BOBLI757_011 trmE trmE 10464 11855 - tRNA modification GTPase TrmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00055 BOBLI757_RS00060 BOBLI757_012 BOBLI757_RS00060 11925 13583 - hypothetical protein gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00060 BOBLI757_RS00065 BOBLI757_013 BOBLI757_RS00065 13835 14185 - ribonuclease P protein component gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00065 BOBLI757_RS00070 BOBLI757_014 rpmH rpmH 14253 14393 - 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00070 BOBLI757_RS00080 BOBLI757_016 BOBLI757_RS00080 16450 17550 + DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00080 BOBLI757_RS00085 BOBLI757_017 gyrB gyrB 17836 20256 + DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00085 BOBLI757_RS00090 BOBLI757_018 BOBLI757_RS00090 20742 21149 + heat shock protein IbpA with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00090 BOBLI757_RS00095 BOBLI757_019 BOBLI757_RS00095 21377 22378 - membrane protein gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00095 BOBLI757_RS00100 BOBLI757_020 BOBLI757_RS00100 22898 23824 + glycyl-tRNA synthetase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00100 BOBLI757_RS00105 BOBLI757_021 BOBLI757_RS00105 23821 25896 + hypothetical protein gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00105 BOBLI757_RS00110 BOBLI757_022 BOBLI757_RS00110 26040 26675 - superoxide dismutase SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00110 BOBLI757_RS00115 BOBLI757_023 BOBLI757_RS00115 27233 29260 + oligopeptidase A gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00115 BOBLI757_RS00120 BOBLI757_024 BOBLI757_RS00120 29333 30973 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00120 BOBLI757_RS00125 BOBLI757_025 ubiA ubiA 31580 32431 + 4-hydroxybenzoate polyprenyltransferase catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate%2C as part of the ubiquinone biosynthesis pathway gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00125 BOBLI757_RS00130 BOBLI757_026 BOBLI757_RS00130 32733 33188 - transcriptional regulator Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00130 BOBLI757_RS00135 BOBLI757_027 BOBLI757_RS00135 33788 35185 + DNA helicase unwinds double stranded DNA gene gene26 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00135 BOBLI757_RS00140 BOBLI757_028 BOBLI757_RS00140 35684 36145 + single-stranded DNA-binding protein gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00140 BOBLI757_RS00145 BOBLI757_029 BOBLI757_RS00145 37121 38767 + sodium:proton antiporter gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00145 BOBLI757_RS00150 BOBLI757_030 BOBLI757_RS00150 39828 41120 + glutamate:protein symporter gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00150 BOBLI757_RS00155 BOBLI757_031 BOBLI757_RS00155 41295 41681 - hypothetical protein gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00155 BOBLI757_RS00160 BOBLI757_032 BOBLI757_RS00160 41799 42812 - ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00160 BOBLI757_RS00165 BOBLI757_033 BOBLI757_RS00165 43066 45954 - valine--tRNA ligase gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00165 BOBLI757_RS00170 BOBLI757_034 BOBLI757_RS00170 45941 46396 - hypothetical protein gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00170 BOBLI757_RS00175 BOBLI757_035 BOBLI757_RS00175 46461 47975 - multifunctional aminopeptidase A catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00175 BOBLI757_RS00180 BOBLI757_036 BOBLI757_RS00180 48162 49250 + hypothetical protein gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00180 BOBLI757_RS00185 BOBLI757_037 BOBLI757_RS00185 49247 50353 + LPS export ABC transporter permease LptG gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00185 BOBLI757_RS00190 BOBLI757_038 BOBLI757_RS00190 51099 51182 + tRNA-Leu tRNA gene37 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00190 BOBLI757_RS00195 BOBLI757_039 BOBLI757_RS00195 51554 52222 + hypothetical protein gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00195 BOBLI757_RS00200 BOBLI757_040 BOBLI757_RS00200 52299 53132 + iron ABC transporter gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00200 BOBLI757_RS00205 BOBLI757_041 BOBLI757_RS00205 53920 54645 - LPS export ABC transporter ATP-binding protein gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00205 BOBLI757_RS00210 BOBLI757_042 BOBLI757_RS00210 54700 55233 - hypothetical protein gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00210 BOBLI757_RS00215 BOBLI757_RS00215 BOBLI757_RS00215 55208 55615 - hypothetical protein gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00215 BOBLI757_RS00220 BOBLI757_044 BOBLI757_RS00220 56164 56412 + cell division protein BolA gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00220 BOBLI757_RS00225 BOBLI757_045 BOBLI757_RS00225 56457 57716 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00225 BOBLI757_RS00230 BOBLI757_046 BOBLI757_RS00230 57804 59174 - serine endoprotease DegQ gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00230 BOBLI757_RS00235 BOBLI757_047 BOBLI757_RS00235 59465 59842 - hypothetical protein gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00235 BOBLI757_RS00240 BOBLI757_048 BOBLI757_RS00240 60050 61195 + hypothetical protein gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00240 BOBLI757_RS00245 BOBLI757_049 BOBLI757_RS00245 61389 61823 + 50S ribosomal protein L13 gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00245 BOBLI757_RS00250 BOBLI757_050 BOBLI757_RS00250 61849 62241 + 30S ribosomal protein S9 gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00250 BOBLI757_RS00255 BOBLI757_051 BOBLI757_RS00255 62753 63256 - hypothetical protein gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00255 BOBLI757_RS00260 BOBLI757_052 BOBLI757_RS00260 63692 64549 + 16S rRNA (cytidine(1402)-2'-O)-methyltransferase gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00260 BOBLI757_RS00265 BOBLI757_054 BOBLI757_RS00265 65504 66052 + membrane protein gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00265 BOBLI757_RS00270 BOBLI757_055 BOBLI757_RS00270 66458 66532 - tRNA-Met tRNA gene53 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00270 BOBLI757_RS00275 BOBLI757_056 BOBLI757_RS00275 66868 68721 - RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00275 BOBLI757_RS00280 BOBLI757_057 dnaG dnaG 68903 70657 - DNA primase synthesizes RNA primers at the replication forks gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00280 BOBLI757_RS00285 BOBLI757_058 rpsU rpsU 70827 71042 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00285 BOBLI757_RS00290 BOBLI757_059 BOBLI757_RS00290 71303 72319 + UGMP family protein universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00290 BOBLI757_RS00295 BOBLI757_060 BOBLI757_RS00295 72383 72964 - glycerol-3-phosphate acyltransferase involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00295 BOBLI757_RS00300 BOBLI757_061 BOBLI757_RS00300 73141 73503 + hypothetical protein gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00300 BOBLI757_RS00305 BOBLI757_062 BOBLI757_RS00305 73607 74434 + UDP pyrophosphate phosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00305 BOBLI757_RS00310 BOBLI757_063 BOBLI757_RS00310 74503 75732 - hypothetical protein gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00310 BOBLI757_RS00315 BOBLI757_RS00315 BOBLI757_RS00315 76794 78169 + heptose 1-phosphate adenyltransferase catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D%2CD-heptose-1%2C7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D%2CD-heptose gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00315 BOBLI757_RS00320 BOBLI757_067 BOBLI757_RS00320 79600 80325 + acyl-phosphate glycerol 3-phosphate acyltransferase gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00320 BOBLI757_RS00325 BOBLI757_068 BOBLI757_RS00325 80892 82082 - cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00325 BOBLI757_RS00330 BOBLI757_069 BOBLI757_RS00330 82453 82525 - tRNA-Phe tRNA gene65 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00330 BOBLI757_RS00335 BOBLI757_070 BOBLI757_RS00335 82811 83134 - hypothetical protein gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00335 BOBLI757_RS00340 BOBLI757_071 groES groES 83672 83965 + molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00340 BOBLI757_RS00345 BOBLI757_072 groEL groEL 84012 85646 + molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00345 BOBLI757_RS00350 BOBLI757_073 BOBLI757_RS00350 86130 86657 + elongation factor P gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00350 BOBLI757_RS00355 BOBLI757_074 BOBLI757_RS00355 86931 90263 - hypothetical protein gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00355 BOBLI757_RS00360 BOBLI757_075 BOBLI757_RS00360 90294 91175 - phosphatidylserine decarboxylase gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00360 BOBLI757_RS00365 BOBLI757_RS00365 BOBLI757_RS00365 91212 91409 + hypothetical protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00365 BOBLI757_RS00370 BOBLI757_076 BOBLI757_RS00370 92068 92607 + oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00370 BOBLI757_RS00375 BOBLI757_077 BOBLI757_RS00375 92783 92855 + tRNA-Gly tRNA gene74 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00375 BOBLI757_RS00380 BOBLI757_078 BOBLI757_RS00380 93721 94185 + tRNA threonylcarbamoyladenosine biosynthesis protein TsaE gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00380 BOBLI757_RS00385 BOBLI757_079 BOBLI757_RS00385 94221 95534 + hypothetical protein gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00385 BOBLI757_RS00390 BOBLI757_080 miaA miaA 96232 97212 + tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00390 BOBLI757_RS00395 BOBLI757_081 BOBLI757_RS00395 97567 98871 + GTPase HflX involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00395 BOBLI757_RS00400 BOBLI757_082 BOBLI757_RS00400 98927 100150 + hypothetical protein gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00400 BOBLI757_RS00405 BOBLI757_083 BOBLI757_RS00405 100216 101229 + cell division protein FtsH with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00405 BOBLI757_RS00410 BOBLI757_084 BOBLI757_RS00410 101431 102729 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00410 BOBLI757_RS00415 BOBLI757_085 BOBLI757_RS00415 103211 103957 + 23S rRNA methyltransferase Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00415 BOBLI757_RS00420 BOBLI757_086 BOBLI757_RS00420 104369 104755 + 30S ribosomal protein S6 gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00420 BOBLI757_RS00425 BOBLI757_087 rpsR rpsR 104975 105202 + 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00425 BOBLI757_RS00430 BOBLI757_088 rplI rplI 105244 105702 + 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00430 BOBLI757_RS00435 BOBLI757_089 BOBLI757_RS00435 105891 106637 + adenosine-3'(2')%2C5'-bisphosphate nucleotidase catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00435 BOBLI757_RS00440 BOBLI757_090 BOBLI757_RS00440 107833 108855 - hypothetical protein gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00440 BOBLI757_RS00445 BOBLI757_091 rpmA rpmA 109208 109471 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00445 BOBLI757_RS00450 BOBLI757_092 rplU rplU 109493 109807 - 50S ribosomal protein L21 gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00450 BOBLI757_RS00455 BOBLI757_093 BOBLI757_RS00455 110047 111015 + octaprenyl diphosphate synthase gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00455 BOBLI757_RS00460 BOBLI757_094 BOBLI757_RS00460 111344 111871 + inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00460 BOBLI757_RS00465 BOBLI757_095 greA greA 112824 113300 + transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00465 BOBLI757_RS00470 BOBLI757_096 rrmJ rrmJ 113815 114441 + 23S rRNA methyltransferase Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00470 BOBLI757_RS00475 BOBLI757_097 hflB hflB 114504 116318 + ATP-dependent metalloprotease inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00475 BOBLI757_RS00480 BOBLI757_098 folP folP 116543 117379 + dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00480 BOBLI757_RS00485 BOBLI757_099 glmM glmM 117376 118716 + phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00485 BOBLI757_RS00490 BOBLI757_100 BOBLI757_RS00490 118912 119232 + preprotein translocase subunit SecG gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00490 BOBLI757_RS00495 BOBLI757_101 BOBLI757_RS00495 119311 119394 + tRNA-Leu tRNA gene98 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00495 BOBLI757_RS00500 BOBLI757_102 BOBLI757_RS00500 119509 119585 + tRNA-Met tRNA gene99 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00500 BOBLI757_RS00505 BOBLI757_103 BOBLI757_RS00505 119739 120212 + hypothetical protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00505 BOBLI757_RS00510 BOBLI757_104 nusA nusA 120233 121729 + transcription elongation factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00510 BOBLI757_RS00515 BOBLI757_105 infB infB 121767 124451 + translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00515 BOBLI757_RS00520 BOBLI757_106 rbfA rbfA 124555 124944 + ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00520 BOBLI757_RS00525 BOBLI757_107 truB truB 124937 125908 + tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00525 BOBLI757_RS00530 BOBLI757_108 BOBLI757_RS00530 125961 126230 + 30S ribosomal protein S15 gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00530 BOBLI757_RS00535 BOBLI757_109 BOBLI757_RS00535 126424 128511 + polynucleotide phosphorylase/polyadenylase gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00535 BOBLI757_RS00540 BOBLI757_110 BOBLI757_RS00540 129319 131025 + DEAD/DEAH box helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00540 BOBLI757_RS00545 BOBLI757_111 BOBLI757_RS00545 131093 131494 + hypothetical protein gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00545 BOBLI757_RS00550 BOBLI757_112 thrA thrA 132595 135054 + aspartate kinase multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine%3B functions in a number of amino acid biosynthetic pathways gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00550 BOBLI757_RS00555 BOBLI757_113 BOBLI757_RS00555 135069 136001 + homoserine kinase gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00555 BOBLI757_RS00560 BOBLI757_114 BOBLI757_RS00560 136005 137303 + threonine synthase gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00560 BOBLI757_RS00565 BOBLI757_115 dnaK dnaK 137783 139693 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00565 BOBLI757_RS00570 BOBLI757_116 BOBLI757_RS00570 139842 140963 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00570 BOBLI757_RS00575 BOBLI757_117 rpsT rpsT 141008 141271 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00575 BOBLI757_RS00580 BOBLI757_118 BOBLI757_RS00580 141577 142497 + hypothetical protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00580 BOBLI757_RS00585 BOBLI757_119 ileS ileS 142545 145370 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00585 BOBLI757_RS00590 BOBLI757_120 BOBLI757_RS00590 145370 145852 + signal peptidase II gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00590 BOBLI757_RS00595 BOBLI757_121 ispH ispH 146042 146983 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00595 BOBLI757_RS00600 BOBLI757_122 BOBLI757_RS00600 147404 148228 + 4-hydroxy-tetrahydrodipicolinate reductase gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00600 BOBLI757_RS00605 BOBLI757_123 BOBLI757_RS00605 148464 149618 + carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00605 BOBLI757_RS00610 BOBLI757_124 carB carB 149631 152870 + carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00610 BOBLI757_RS00615 BOBLI757_125 BOBLI757_RS00615 152977 153519 + hypothetical protein gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00615 BOBLI757_RS00620 BOBLI757_126 BOBLI757_RS00620 153843 154634 - hypothetical protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00620 BOBLI757_RS00625 BOBLI757_RS00625 BOBLI757_RS00625 154660 155642 - hypothetical protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00625 BOBLI757_RS00630 BOBLI757_128 BOBLI757_RS00630 155635 156963 - hypothetical protein gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00630 BOBLI757_RS00635 BOBLI757_129 BOBLI757_RS00635 157010 159346 - hypothetical protein gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00635 BOBLI757_RS00640 BOBLI757_130 BOBLI757_RS00640 160119 161666 + 2-isopropylmalate synthase gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00640 BOBLI757_RS00645 BOBLI757_131 BOBLI757_RS00645 161722 162807 + 3-isopropylmalate dehydrogenase gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00645 BOBLI757_RS00650 BOBLI757_132 BOBLI757_RS00650 162830 164227 + isopropylmalate isomerase dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00650 BOBLI757_RS00655 BOBLI757_133 leuD leuD 164241 164846 + isopropylmalate isomerase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis%3B forms a heterodimer of LeuC/D gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00655 BOBLI757_RS00660 BOBLI757_134 BOBLI757_RS00660 164995 165948 + 16S rRNA (cytosine(1402)-N(4))-methyltransferase gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00660 BOBLI757_RS00665 BOBLI757_135 BOBLI757_RS00665 165955 166272 + hypothetical protein gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00665 BOBLI757_RS00670 BOBLI757_136 BOBLI757_RS00670 166328 168013 + cell division protein FtsI penicillin-binding protein 3%3B transpeptidase involved in septal peptidoglycan synthesis gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00670 BOBLI757_RS00675 BOBLI757_137 murE murE 168046 169533 + UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00675 BOBLI757_RS00680 BOBLI757_138 murF murF 169534 170910 + UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00680 BOBLI757_RS00685 BOBLI757_139 mraY mraY 170898 171971 + phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00685 BOBLI757_RS00690 BOBLI757_140 murD murD 171993 173306 + UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00690 BOBLI757_RS00695 BOBLI757_141 BOBLI757_RS00695 173350 174468 + cell division protein FtsW integral membrane protein involved in stabilizing FstZ ring during cell division gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00695 BOBLI757_RS00700 BOBLI757_142 murG murG 174516 175556 + UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00700 BOBLI757_RS00705 BOBLI757_143 BOBLI757_RS00705 175630 177075 + UDP-N-acetylmuramate--alanine ligase gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00705 BOBLI757_RS00710 BOBLI757_144 BOBLI757_RS00710 177209 177976 + hypothetical protein gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00710 BOBLI757_RS00715 BOBLI757_145 ftsA ftsA 178014 179276 + cell division protein FtsA ATP-binding involved in recruitment of FtsK to Z ring%3B essential cell division protein%3B colocalizes with FtsZ through direct interaction to the septal ring structure%3B structurally similar to eukaryotic actin%3B binds directly to the cell membrane gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00715 BOBLI757_RS00720 BOBLI757_146 BOBLI757_RS00720 179347 180510 + cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00720 BOBLI757_RS00725 BOBLI757_147 lpxC lpxC 180626 181531 + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase zinc-dependent%3B catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00725 BOBLI757_RS00730 BOBLI757_148 secA secA 182427 185039 + preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00730 BOBLI757_RS00735 BOBLI757_149 aceE aceE 188071 190734 + pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00735 BOBLI757_RS00740 BOBLI757_150 BOBLI757_RS00740 190756 192018 + branched-chain alpha-keto acid dehydrogenase subunit E2 gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00740 BOBLI757_RS00745 BOBLI757_151 BOBLI757_RS00745 192178 193614 + dihydrolipoamide dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00745 BOBLI757_RS00750 BOBLI757_152 BOBLI757_RS00750 194111 194614 - hypothetical protein gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00750 BOBLI757_RS00755 BOBLI757_153 dksA dksA 194912 195367 - RNA polymerase-binding transcription factor gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00755 BOBLI757_RS00760 BOBLI757_154 mrcB mrcB 196013 198373 + bifunctional glycosyl transferase/transpeptidase penicillin-binding protein 1b%3B contains transglycosylase and transpeptidase activity%3B major enzyme for peptidoglycan biosynthesis in Escherichia coli%3B transmembrane protein%3B forms dimers%3B three variants%2C one of which may be a degradation product%2C while the other appears to result from an alternative initiation site%2C are found within the cell gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00760 BOBLI757_RS00765 BOBLI757_RS00765 BOBLI757_RS00765 198469 198651 + hypothetical protein gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00765 BOBLI757_RS00770 BOBLI757_155 BOBLI757_RS00770 199050 199397 + iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00770 BOBLI757_RS00775 BOBLI757_156 pyrG pyrG 200444 202090 + CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00775 BOBLI757_RS00780 BOBLI757_157 eno eno 202205 203506 + enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00780 BOBLI757_RS00785 BOBLI757_158 BOBLI757_RS00785 203820 205640 + hypothetical protein gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00785 BOBLI757_RS00790 BOBLI757_159 BOBLI757_RS00790 205641 207356 + sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00790 BOBLI757_RS00795 BOBLI757_160 BOBLI757_RS00795 207369 208106 + phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00795 BOBLI757_RS00800 BOBLI757_161 BOBLI757_RS00800 208451 209908 + sirohydrochlorin ferrochelatase gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00800 BOBLI757_RS00805 BOBLI757_162 BOBLI757_RS00805 209923 210837 + sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00805 BOBLI757_RS00810 BOBLI757_163 cysN cysN 210851 212293 + sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00810 BOBLI757_RS00815 BOBLI757_164 BOBLI757_RS00815 212298 212918 + adenylylsulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00815 BOBLI757_RS00820 BOBLI757_165 BOBLI757_RS00820 213030 213311 + hypothetical protein gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00820 BOBLI757_RS00825 BOBLI757_166 BOBLI757_RS00825 213364 214065 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00825 BOBLI757_RS00830 BOBLI757_167 ispF ispF 214079 214546 + 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00830 BOBLI757_RS00840 BOBLI757_169 BOBLI757_RS00840 216801 219434 + alanyl-tRNA synthetase gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00840 BOBLI757_RS00845 BOBLI757_170 BOBLI757_RS00845 219554 219721 + carbon storage regulator affects carbohydrate metabolism%3B has regulatory role in many processes gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00845 BOBLI757_RS00850 BOBLI757_171 BOBLI757_RS00850 219933 220021 + tRNA-Ser tRNA gene169 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00850 BOBLI757_RS00855 BOBLI757_172 BOBLI757_RS00855 220050 220123 + tRNA-Arg tRNA gene170 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00855 BOBLI757_RS00860 BOBLI757_173 BOBLI757_RS00860 220666 222036 + signal recognition particle gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00860 BOBLI757_RS00865 BOBLI757_174 BOBLI757_RS00865 222146 222394 + 30S ribosomal protein S16 gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00865 BOBLI757_RS00870 BOBLI757_175 rimM rimM 222410 222970 + 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00870 BOBLI757_RS00875 BOBLI757_176 trmD trmD 223017 223760 + tRNA (guanine(37)-N(1))-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00875 BOBLI757_RS00880 BOBLI757_177 BOBLI757_RS00880 223855 224202 + 50S ribosomal protein L19 gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00880 BOBLI757_RS00885 BOBLI757_178 BOBLI757_RS00885 224829 225914 + phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00885 BOBLI757_RS00890 BOBLI757_179 BOBLI757_RS00890 225911 227041 + hypothetical protein gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00890 BOBLI757_RS00895 BOBLI757_180 BOBLI757_RS00895 227278 227880 - hypothetical protein gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00895 BOBLI757_RS00900 BOBLI757_181 BOBLI757_RS00900 228062 228757 - hypothetical protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00900 BOBLI757_RS00905 BOBLI757_182 BOBLI757_RS00905 228916 229860 + hypothetical protein gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00905 BOBLI757_RS00910 BOBLI757_183 BOBLI757_RS00910 230134 232707 + protein disaggregation chaperone gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00910 BOBLI757_RS00915 BOBLI757_184 murB murB 233419 234459 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00915 BOBLI757_RS00920 BOBLI757_185 BOBLI757_RS00920 234596 235321 + hypothetical protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00920 BOBLI757_RS00925 BOBLI757_186 BOBLI757_RS00925 236649 236721 + tRNA-Thr tRNA gene184 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00925 BOBLI757_RS00930 BOBLI757_187 BOBLI757_RS00930 236744 236828 + tRNA-Tyr tRNA gene185 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00930 BOBLI757_RS00935 BOBLI757_189 BOBLI757_RS00935 237077 237152 + tRNA-Thr tRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00935 BOBLI757_RS00940 BOBLI757_190 BOBLI757_RS00940 237459 237929 + bacterioferritin iron storage protein gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00940 BOBLI757_RS00945 BOBLI757_191 rpsJ rpsJ 238360 238671 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00945 BOBLI757_RS00950 BOBLI757_192 BOBLI757_RS00950 238771 239385 + 50S ribosomal protein L3 gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00950 BOBLI757_RS00955 BOBLI757_193 rplD rplD 239461 240084 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00955 BOBLI757_RS00960 BOBLI757_194 rplW rplW 240085 240387 + 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00960 BOBLI757_RS00965 BOBLI757_195 BOBLI757_RS00965 240429 241253 + 50S ribosomal protein L2 gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00965 BOBLI757_RS00970 BOBLI757_196 BOBLI757_RS00970 241283 241564 + 30S ribosomal protein S19 gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00970 BOBLI757_RS00975 BOBLI757_197 BOBLI757_RS00975 241578 241910 + 50S ribosomal protein L22 gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00975 BOBLI757_RS00980 BOBLI757_198 BOBLI757_RS00980 241966 242679 + 30S ribosomal protein S3 gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00980 BOBLI757_RS00985 BOBLI757_199 BOBLI757_RS00985 242701 243111 + 50S ribosomal protein L16 gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00985 BOBLI757_RS00990 BOBLI757_200 BOBLI757_RS00990 243111 243326 + 50S ribosomal protein L29 gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00990 BOBLI757_RS00995 BOBLI757_201 BOBLI757_RS00995 243319 243576 + 30S ribosomal protein S17 gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS00995 BOBLI757_RS01000 BOBLI757_202 BOBLI757_RS01000 243651 244022 + 50S ribosomal protein L14 gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01000 BOBLI757_RS01005 BOBLI757_203 BOBLI757_RS01005 244089 244403 + 50S ribosomal protein L24 gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01005 BOBLI757_RS01010 BOBLI757_204 BOBLI757_RS01010 244428 244967 + 50S ribosomal protein L5 gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01010 BOBLI757_RS01015 BOBLI757_205 rpsN rpsN 245004 245309 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01015 BOBLI757_RS01020 BOBLI757_206 BOBLI757_RS01020 245356 245748 + 30S ribosomal protein S8 gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01020 BOBLI757_RS01025 BOBLI757_207 BOBLI757_RS01025 245774 246310 + 50S ribosomal protein L6 gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01025 BOBLI757_RS01030 BOBLI757_208 BOBLI757_RS01030 246362 246712 + 50S ribosomal protein L18 gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01030 BOBLI757_RS01035 BOBLI757_209 BOBLI757_RS01035 246762 247289 + 30S ribosomal protein S5 gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01035 BOBLI757_RS01040 BOBLI757_210 rpmD rpmD 247270 247452 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01040 BOBLI757_RS01045 BOBLI757_211 BOBLI757_RS01045 247455 247889 + 50S ribosomal protein L15 gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01045 BOBLI757_RS01050 BOBLI757_212 secY secY 247898 249238 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01050 BOBLI757_RS01055 BOBLI757_213 BOBLI757_RS01055 249283 249399 + 50S ribosomal protein L36 gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01055 BOBLI757_RS01060 BOBLI757_214 BOBLI757_RS01060 249520 249876 + 30S ribosomal protein S13 gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01060 BOBLI757_RS01065 BOBLI757_215 BOBLI757_RS01065 249897 250289 + 30S ribosomal protein S11 gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01065 BOBLI757_RS01070 BOBLI757_216 BOBLI757_RS01070 250328 250948 + 30S ribosomal protein S4 gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01070 BOBLI757_RS01075 BOBLI757_217 BOBLI757_RS01075 250974 251987 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01075 BOBLI757_RS01080 BOBLI757_218 rplQ rplQ 252029 252400 + 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01080 BOBLI757_RS01085 BOBLI757_219 fmt fmt 252544 253503 - methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01085 BOBLI757_RS01090 BOBLI757_220 BOBLI757_RS01090 253573 254019 - peptide deformylase gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01090 BOBLI757_RS01095 BOBLI757_221 BOBLI757_RS01095 254622 255209 + tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01095 BOBLI757_RS01100 BOBLI757_222 BOBLI757_RS01100 255272 256087 + shikimate dehydrogenase gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01100 BOBLI757_RS01105 BOBLI757_223 BOBLI757_RS01105 256472 256589 + 5S ribosomal RNA rRNA gene220 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01105 BOBLI757_RS01110 BOBLI757_224 BOBLI757_RS01110 256867 257619 - hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01110 BOBLI757_RS01115 BOBLI757_225 BOBLI757_RS01115 257680 258360 + hypothetical protein gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01115 BOBLI757_RS01120 BOBLI757_226 BOBLI757_RS01120 258412 258885 - ribonuclease H gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01120 BOBLI757_RS01125 BOBLI757_227 BOBLI757_RS01125 258940 259713 + DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01125 BOBLI757_RS01130 BOBLI757_228 gmhA gmhA 260108 260692 + phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01130 BOBLI757_RS01135 BOBLI757_229 BOBLI757_RS01135 261075 261148 - tRNA-Thr tRNA gene226 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01135 BOBLI757_RS01140 BOBLI757_230 BOBLI757_RS01140 261247 261849 - peroxiredoxin gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01140 BOBLI757_RS01145 BOBLI757_231 yajC yajC 263392 263730 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01145 BOBLI757_RS01150 BOBLI757_RS01150 BOBLI757_RS01150 263746 263985 + hypothetical protein gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01150 BOBLI757_RS01170 BOBLI757_RS01170 BOBLI757_RS01170 265609 266517 + hypothetical protein gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01170 BOBLI757_RS01175 BOBLI757_RS01175 BOBLI757_RS01175 266969 267199 + hypothetical protein gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01175 BOBLI757_RS01180 BOBLI757_235 BOBLI757_RS01180 268807 269226 + hypothetical protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01180 BOBLI757_RS01185 BOBLI757_236 BOBLI757_RS01185 269372 269839 + phosphatidylglycerophosphatase hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01185 BOBLI757_RS01190 BOBLI757_237 BOBLI757_RS01190 270025 271887 - 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01190 BOBLI757_RS01195 BOBLI757_238 BOBLI757_RS01195 271916 272829 - geranyl transferase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01195 BOBLI757_RS01200 BOBLI757_239 BOBLI757_RS01200 273212 274678 + tRNA s(4)U8 sulfurtransferase catalyzes the conversion of uridine to 4-thiouridinine tRNA%3B also required for the synthesis of the thiazole moiety gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01200 BOBLI757_RS01205 BOBLI757_240 BOBLI757_RS01205 274822 276024 - hypothetical protein gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01205 BOBLI757_RS01210 BOBLI757_241 BOBLI757_RS01210 276101 276961 - protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01210 BOBLI757_RS01215 BOBLI757_242 BOBLI757_RS01215 276976 277281 - cytochrome O ubiquinol oxidase gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01215 BOBLI757_RS01220 BOBLI757_243 BOBLI757_RS01220 277278 277850 - cytochrome o ubiquinol oxidase subunit III gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01220 BOBLI757_RS01225 BOBLI757_244 BOBLI757_RS01225 277899 279890 - cytochrome o ubiquinol oxidase subunit I gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01225 BOBLI757_RS01230 BOBLI757_245 BOBLI757_RS01230 279969 280820 - hypothetical protein gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01230 BOBLI757_RS01235 BOBLI757_246 BOBLI757_RS01235 281392 282015 + hypothetical protein gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01235 BOBLI757_RS01240 BOBLI757_247 clpX clpX 282093 283349 + ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01240 BOBLI757_RS01245 BOBLI757_248 BOBLI757_RS01245 283508 283765 - hypothetical protein gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01245 BOBLI757_RS01250 BOBLI757_249 BOBLI757_RS01250 284412 285122 - YggS family pyridoxal phosphate enzyme gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01250 BOBLI757_RS01255 BOBLI757_250 BOBLI757_RS01255 285398 285802 - hypothetical protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01255 BOBLI757_RS01260 BOBLI757_251 BOBLI757_RS01260 285811 286374 - hypothetical protein gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01260 BOBLI757_RS01265 BOBLI757_252 BOBLI757_RS01265 287050 288216 - S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01265 BOBLI757_RS01270 BOBLI757_253 BOBLI757_RS01270 288727 289647 + agmatinase catalyzes the formation of putrescine from agmatine gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01270 BOBLI757_RS01275 BOBLI757_254 BOBLI757_RS01275 290514 291692 + phosphoglycerate kinase gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01275 BOBLI757_RS01280 BOBLI757_255 BOBLI757_RS01280 291771 292847 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01280 BOBLI757_RS01285 BOBLI757_256 BOBLI757_RS01285 293083 293739 + hypothetical protein catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01285 BOBLI757_RS01290 BOBLI757_257 BOBLI757_RS01290 293975 294580 - 5-formyltetrahydrofolate cyclo-ligase gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01290 BOBLI757_RS01295 BOBLI757_258 BOBLI757_RS01295 294822 295151 - Z-ring-associated protein gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01295 BOBLI757_RS01300 BOBLI757_259 BOBLI757_RS01300 295592 296770 + hypothetical protein gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01300 BOBLI757_RS01305 BOBLI757_260 BOBLI757_RS01305 296803 298002 + hypothetical protein gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01305 BOBLI757_RS01310 BOBLI757_261 BOBLI757_RS01310 298311 299303 - hypothetical protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01310 BOBLI757_RS01315 BOBLI757_262 BOBLI757_RS01315 300078 301058 + peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01315 BOBLI757_RS01320 BOBLI757_263 lysS lysS 301098 302597 + lysine--tRNA ligase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01320 BOBLI757_RS01325 BOBLI757_264 BOBLI757_RS01325 303255 304511 + diaminopimelate decarboxylase catalyzes the decarboxylation of diaminopimelate into lysine%3B pyridoxal phosphate(PLP)-binding gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01325 BOBLI757_RS01330 BOBLI757_265 tas tas 304675 305721 - aldo/keto reductase complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain%3B member of the aldo/keto reductase 2 family%3B crystal structure of purified Escherichia coli protein shows bound NADPH gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01330 BOBLI757_RS01335 BOBLI757_266 BOBLI757_RS01335 306475 306960 + RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01335 BOBLI757_RS01340 BOBLI757_267 BOBLI757_RS01340 307209 308066 + prolipoprotein diacylglyceryl transferase gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01340 BOBLI757_RS01345 BOBLI757_268 BOBLI757_RS01345 308464 311889 + hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01345 BOBLI757_RS01350 BOBLI757_269 BOBLI757_RS01350 312265 314112 - exodeoxyribonuclease V subunit alpha gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01350 BOBLI757_RS01355 BOBLI757_270 BOBLI757_RS01355 314231 317785 - exodeoxyribonuclease V subunit beta gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01355 BOBLI757_RS01360 BOBLI757_271 dapD dapD 317943 318767 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-carboxylate N-succinyltransferase catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01360 BOBLI757_RS01365 BOBLI757_272 BOBLI757_RS01365 319174 319968 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01365 BOBLI757_RS01370 BOBLI757_273 BOBLI757_RS01370 320422 321147 + 30S ribosomal protein S2 gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01370 BOBLI757_RS01375 BOBLI757_274 BOBLI757_RS01375 321297 322109 + translation elongation factor Ts gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01375 BOBLI757_RS01380 BOBLI757_275 BOBLI757_RS01380 322329 323057 + uridylate kinase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01380 BOBLI757_RS01385 BOBLI757_276 frr frr 323135 323692 + ribosome recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01385 BOBLI757_RS01390 BOBLI757_277 BOBLI757_RS01390 323773 324975 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01390 BOBLI757_RS01395 BOBLI757_278 BOBLI757_RS01395 325151 325900 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01395 BOBLI757_RS01400 BOBLI757_279 cdsA cdsA 325950 326810 + CDP-diglyceride synthetase catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01400 BOBLI757_RS01405 BOBLI757_280 BOBLI757_RS01405 326835 328196 + zinc metallopeptidase RseP catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01405 BOBLI757_RS01410 BOBLI757_281 BOBLI757_RS01410 328239 330668 + outer membrane protein assembly protein YaeT part of a complex with YfgL%2C YfiO%2C and NlpB involved in outer membrane protein biosynthesis%3B involved in the assembly of outer membrane proteins gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01410 BOBLI757_RS01415 BOBLI757_282 BOBLI757_RS01415 330863 331333 + molecular chaperone gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01415 BOBLI757_RS01420 BOBLI757_283 lpxD lpxD 331337 332365 + UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01420 BOBLI757_RS01425 BOBLI757_284 BOBLI757_RS01425 332503 332958 + 3-hydroxyacyl-ACP dehydratase gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01425 BOBLI757_RS01430 BOBLI757_285 BOBLI757_RS01430 332963 333751 + UDP-N-acetylglucosamine acyltransferase catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01430 BOBLI757_RS01435 BOBLI757_286 lpxB lpxB 333757 334896 + lipid-A-disaccharide synthase catalyzes the formation of lipid A disaccharide from UDP-2%2C3-diacylglucosamine and 2%2C3-diacylglucosamine-1-phosphate%2C lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01435 BOBLI757_RS01440 BOBLI757_287 rnhB rnhB 334934 335521 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01440 BOBLI757_RS01445 BOBLI757_288 dnaE dnaE 335574 339065 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01445 BOBLI757_RS01450 BOBLI757_289 BOBLI757_RS01450 339068 340027 + acetyl-CoA carboxylase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01450 BOBLI757_RS01455 BOBLI757_290 BOBLI757_RS01455 340382 341878 + hypothetical protein gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01455 BOBLI757_RS01460 BOBLI757_291 BOBLI757_RS01460 342049 343752 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01460 BOBLI757_RS01465 BOBLI757_292 BOBLI757_RS01465 344649 345128 - hypothetical protein gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01465 BOBLI757_RS01470 BOBLI757_293 BOBLI757_RS01470 345286 346137 - hypothetical protein gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01470 BOBLI757_RS01475 BOBLI757_294 BOBLI757_RS01475 346249 347292 - rod shape-determining protein MreB gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01475 BOBLI757_RS01480 BOBLI757_295 BOBLI757_RS01480 347743 348198 + 3-dehydroquinate dehydratase gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01480 BOBLI757_RS01485 BOBLI757_296 BOBLI757_RS01485 348222 348698 + acetyl-CoA carboxylase gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01485 BOBLI757_RS01490 BOBLI757_297 BOBLI757_RS01490 348688 350049 + acetyl-CoA carboxylase an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01490 BOBLI757_RS01495 BOBLI757_298 tldD tldD 350884 352335 + protease TldD responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17%2C an exported protein that targets the essential topoisomerase II DNA gyrase%3B degrades the E. coli plasmid F-encoded CcdA gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01495 BOBLI757_RS01500 BOBLI757_299 pmbA pmbA 352951 354291 + peptidase PMbA protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01500 BOBLI757_RS01505 BOBLI757_300 BOBLI757_RS01505 354838 357174 + DNA-binding protein gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01505 BOBLI757_RS01510 BOBLI757_301 BOBLI757_RS01510 357299 357577 + transcriptional regulator HU subunit alpha histone-like DNA-binding protein gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01510 BOBLI757_RS01515 BOBLI757_RS01515 BOBLI757_RS01515 357835 358017 + hypothetical protein gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01515 BOBLI757_RS01520 BOBLI757_303 BOBLI757_RS01520 358094 358297 - transcriptional regulator with Hns involved in transcriptional regulation of hemolysin%3B non-specific DNA-binding protein which affects the production of multiple proteins gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01520 BOBLI757_RS01525 BOBLI757_304 BOBLI757_RS01525 358789 359352 + adenine phosphoribosyltransferase gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01525 BOBLI757_RS01530 BOBLI757_305 BOBLI757_RS01530 359462 361453 + hypothetical protein gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01530 BOBLI757_RS01535 BOBLI757_306 BOBLI757_RS01535 361623 362276 + hypothetical protein gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01535 BOBLI757_RS01540 BOBLI757_307 BOBLI757_RS01540 362464 363186 - hypothetical protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01540 BOBLI757_RS01545 BOBLI757_308 cysS cysS 363498 364910 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01545 BOBLI757_RS01550 BOBLI757_309 BOBLI757_RS01550 365021 365878 - methenyltetrahydrofolate cyclohydrolase gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01550 BOBLI757_RS01555 BOBLI757_310 BOBLI757_RS01555 366053 366129 + tRNA-Arg tRNA gene308 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01555 BOBLI757_RS01560 BOBLI757_311 BOBLI757_RS01560 366710 367645 + membrane protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01560 BOBLI757_RS01565 BOBLI757_312 BOBLI757_RS01565 367993 369102 - cell wall shape-determining protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01565 BOBLI757_RS01570 BOBLI757_313 BOBLI757_RS01570 369139 371019 - penicillin-binding protein 2 gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01570 BOBLI757_RS01575 BOBLI757_314 BOBLI757_RS01575 371127 371480 - ribosome silencing factor RsfS gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01575 BOBLI757_RS01580 BOBLI757_315 BOBLI757_RS01580 372017 373024 - hypothetical protein gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01580 BOBLI757_RS01585 BOBLI757_316 BOBLI757_RS01585 373093 373554 - hypothetical protein gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01585 BOBLI757_RS01590 BOBLI757_317 leuS leuS 373611 376196 - leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01590 BOBLI757_RS01595 BOBLI757_318 lnt lnt 376854 378395 - apolipoprotein acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01595 BOBLI757_RS01600 BOBLI757_319 BOBLI757_RS01600 378432 379277 - magnesium/cobalt efflux protein CorC involved in the transport of magnesium and cobalt ions gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01600 BOBLI757_RS01605 BOBLI757_320 BOBLI757_RS01605 379291 379761 - rRNA maturation RNase YbeY gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01605 BOBLI757_RS01610 BOBLI757_321 BOBLI757_RS01610 379822 380835 - nucleoside triphosphate hydrolase gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01610 BOBLI757_RS01615 BOBLI757_322 BOBLI757_RS01615 381280 382473 + hypothetical protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01615 BOBLI757_RS01620 BOBLI757_323 BOBLI757_RS01620 382825 382898 - tRNA-Gln tRNA gene321 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01620 BOBLI757_RS01625 BOBLI757_324 BOBLI757_RS01625 382936 383018 - tRNA-Leu tRNA gene322 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01625 BOBLI757_RS01630 BOBLI757_325 BOBLI757_RS01630 383135 383209 - tRNA-Met tRNA gene323 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01630 BOBLI757_RS01635 BOBLI757_326 nagA nagA 383589 384749 - N-acetylglucosamine-6-phosphate deacetylase catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01635 BOBLI757_RS01640 BOBLI757_327 nagB nagB 384752 385567 - glucosamine-6-phosphate deaminase catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01640 BOBLI757_RS01645 BOBLI757_328 BOBLI757_RS01645 386266 387948 + glutamine--tRNA ligase catalyzes a two-step reaction%2C first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01645 BOBLI757_RS01650 BOBLI757_329 BOBLI757_RS01650 388055 388573 - flavodoxin FldA An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01650 BOBLI757_RS01655 BOBLI757_330 BOBLI757_RS01655 388979 389761 - hypothetical protein gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01655 BOBLI757_RS01660 BOBLI757_331 BOBLI757_RS01660 389963 391612 + phosphoglucomutase catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01660 BOBLI757_RS01665 BOBLI757_332 BOBLI757_RS01665 392263 392640 + succinate dehydrogenase gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01665 BOBLI757_RS01670 BOBLI757_333 BOBLI757_RS01670 392637 392981 + hypothetical protein gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01670 BOBLI757_RS01675 BOBLI757_334 sdhA sdhA 392984 394756 + succinate dehydrogenase part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01675 BOBLI757_RS01680 BOBLI757_335 sdhB sdhB 394804 395526 + succinate dehydrogenase part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers)%3B SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556%3B SdhC binds ubiquinone%3B oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol%3B the catalytic subunits are similar to fumarate reductase gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01680 BOBLI757_RS01685 BOBLI757_336 BOBLI757_RS01685 395710 398502 + 2-oxoglutarate dehydrogenase gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01685 BOBLI757_RS01690 BOBLI757_337 BOBLI757_RS01690 398529 399716 + dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex%3B catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01690 BOBLI757_RS01695 BOBLI757_338 sucC sucC 399806 400966 + succinyl-CoA synthetase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01695 BOBLI757_RS01700 BOBLI757_339 BOBLI757_RS01700 400984 401856 + succinyl-CoA synthetase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01700 BOBLI757_RS01705 BOBLI757_340 BOBLI757_RS01705 402271 402930 + colicin uptake protein TolQ membrane spanning protein in TolA-TolQ-TolR complex%3B involved in the tonB-independent uptake of group A colicins gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01705 BOBLI757_RS01710 BOBLI757_341 BOBLI757_RS01710 402974 403402 + hypothetical protein gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01710 BOBLI757_RS01720 BOBLI757_343 tolB tolB 404411 405679 + translocation protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01720 BOBLI757_RS01725 BOBLI757_344 BOBLI757_RS01725 405736 406230 + hypothetical protein gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01725 BOBLI757_RS01730 BOBLI757_345 BOBLI757_RS01730 406227 407012 + hypothetical protein gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01730 BOBLI757_RS01735 BOBLI757_346 gpmA gpmA 407242 407943 - phosphoglyceromutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01735 BOBLI757_RS01740 BOBLI757_347 BOBLI757_RS01740 408278 409270 + hypothetical protein gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01740 BOBLI757_RS01745 BOBLI757_348 BOBLI757_RS01745 409556 410266 + membrane protein gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01745 BOBLI757_RS01750 BOBLI757_350 BOBLI757_RS01750 411624 412193 - peptidyl-tRNA hydrolase Enables the recycling of peptidyl-tRNAs produced at termination of translation gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01750 BOBLI757_RS01755 BOBLI757_351 BOBLI757_RS01755 412426 413379 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01755 BOBLI757_RS01760 BOBLI757_352 BOBLI757_RS01760 413483 414337 - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01760 BOBLI757_RS01765 BOBLI757_353 prfA prfA 414819 415895 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01765 BOBLI757_RS01770 BOBLI757_354 BOBLI757_RS01770 415908 416741 + SAM-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01770 BOBLI757_RS01775 BOBLI757_355 BOBLI757_RS01775 417143 417997 + 2-dehydro-3-deoxyphosphooctonate aldolase catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01775 BOBLI757_RS01780 BOBLI757_356 thrS thrS 418415 419650 + threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01780 BOBLI757_RS01785 BOBLI757_RS01785 BOBLI757_RS01785 419824 420159 + translation initiation factor IF-3 gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01785 BOBLI757_RS01790 BOBLI757_358 BOBLI757_RS01790 420266 420463 + 50S ribosomal protein L35 gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01790 BOBLI757_RS01795 BOBLI757_359 rplT rplT 420522 420881 + 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01795 BOBLI757_RS01800 BOBLI757_360 BOBLI757_RS01800 421115 422101 + phenylalanyl-tRNA synthetase gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01800 BOBLI757_RS01805 BOBLI757_361 BOBLI757_RS01805 422204 424516 + phenylalanine--tRNA ligase subunit beta gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01805 BOBLI757_RS01810 BOBLI757_362 lplA lplA 424625 425638 + lipoate--protein ligase Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01810 BOBLI757_RS01815 BOBLI757_363 sufA sufA 425998 426381 + (Fe-S)-cluster assembly protein functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01815 BOBLI757_RS01820 BOBLI757_364 BOBLI757_RS01820 426397 427896 + Fe-S cluster assembly protein SufB with SufCD activates cysteine desulfurase SufS gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01820 BOBLI757_RS01825 BOBLI757_365 sufC sufC 427980 428720 + Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01825 BOBLI757_RS01830 BOBLI757_366 BOBLI757_RS01830 428701 429984 + Fe-S cluster assembly protein SufD gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01830 BOBLI757_RS01835 BOBLI757_367 BOBLI757_RS01835 429981 431222 + cysteine sulfinate desulfinase gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01835 BOBLI757_RS01840 BOBLI757_368 BOBLI757_RS01840 431243 431668 + hypothetical protein gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01840 BOBLI757_RS01845 BOBLI757_369 BOBLI757_RS01845 431890 431962 - tRNA-Val tRNA gene366 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01845 BOBLI757_RS01850 BOBLI757_RS01850 BOBLI757_RS01850 432320 432571 + hypothetical protein gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01850 BOBLI757_RS01855 BOBLI757_371 BOBLI757_RS01855 433143 433484 + glutaredoxin gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01855 BOBLI757_RS01860 BOBLI757_372 BOBLI757_RS01860 433623 434258 - ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01860 BOBLI757_RS01865 BOBLI757_373 BOBLI757_RS01865 434836 435276 + SlyA family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01865 BOBLI757_RS01870 BOBLI757_374 BOBLI757_RS01870 436025 437305 + tyrosyl-tRNA synthetase gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01870 BOBLI757_RS01875 BOBLI757_375 BOBLI757_RS01875 437362 438006 - endonuclease III DNA-(apurinic or apyrimidinic site) lyase%3B has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity%3B removed damaged DNA at cytosines%2C thymines and guanines gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01875 BOBLI757_RS01880 BOBLI757_376 fumC fumC 438030 439430 - fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01880 BOBLI757_RS01885 BOBLI757_377 BOBLI757_RS01885 439941 441662 + hypothetical protein gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01885 BOBLI757_RS01890 BOBLI757_378 BOBLI757_RS01890 441869 442468 - hypothetical protein gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01890 BOBLI757_RS01895 BOBLI757_379 BOBLI757_RS01895 442782 443558 - 3-deoxy-manno-octulosonate cytidylyltransferase CMP-2-keto-3-deoxyoctulosonic acid synthetase%3B catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01895 BOBLI757_RS01900 BOBLI757_381 lpxK lpxK 443987 444979 - tetraacyldisaccharide 4'-kinase transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1%2C4'-bis-phosphate gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01900 BOBLI757_RS01905 BOBLI757_382 BOBLI757_RS01905 444979 446730 - lipid transporter ATP-binding/permease involved in the transport of lipid A across the inner membrane gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01905 BOBLI757_RS01910 BOBLI757_383 rpsA rpsA 447223 448905 - 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01910 BOBLI757_RS01915 BOBLI757_384 BOBLI757_RS01915 449036 449710 - cytidylate kinase gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01915 BOBLI757_RS01920 BOBLI757_385 BOBLI757_RS01920 449811 451097 - 3-phosphoshikimate 1-carboxyvinyltransferase gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01920 BOBLI757_RS01925 BOBLI757_386 BOBLI757_RS01925 451227 452315 - 3-phosphoserine/phosphohydroxythreonine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01925 BOBLI757_RS01930 BOBLI757_387 BOBLI757_RS01930 452509 453819 - seryl-tRNA synthetase gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01930 BOBLI757_RS01935 BOBLI757_388 BOBLI757_RS01935 454180 454788 - outer membrane lipoprotein carrier protein LolA gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01935 BOBLI757_RS01945 BOBLI757_RS01945 BOBLI757_RS01945 457144 457392 - hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01945 BOBLI757_RS01950 BOBLI757_390 BOBLI757_RS01950 457893 458849 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01950 BOBLI757_RS01955 BOBLI757_391 BOBLI757_RS01955 459137 459355 + translation initiation factor IF-1 gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01955 BOBLI757_RS01960 BOBLI757_392 BOBLI757_RS01960 459946 460590 + hypothetical protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01960 BOBLI757_RS01965 BOBLI757_RS01965 BOBLI757_RS01965 461449 461988 - hypothetical protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01965 BOBLI757_RS01970 BOBLI757_394 BOBLI757_RS01970 462443 462913 - hypothetical protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01970 BOBLI757_RS01975 BOBLI757_395 BOBLI757_RS01975 463487 464869 - adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01975 BOBLI757_RS01980 BOBLI757_396 mnmA mnmA 465257 466363 - tRNA 2-thiouridylase catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01980 BOBLI757_RS01985 BOBLI757_397 BOBLI757_RS01985 466761 468014 - hypothetical protein gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01985 BOBLI757_RS01990 BOBLI757_398 lolD lolD 468046 468738 - lipoprotein ABC transporter ATP-binding protein outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01990 BOBLI757_RS01995 BOBLI757_399 BOBLI757_RS01995 468728 469954 - hypothetical protein gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS01995 BOBLI757_RS02000 BOBLI757_RS02000 BOBLI757_RS02000 470038 470637 - hypothetical protein gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02000 BOBLI757_RS02005 BOBLI757_401 BOBLI757_RS02005 470818 471165 - purine nucleoside phosphoramidase gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02005 BOBLI757_RS02010 BOBLI757_402 BOBLI757_RS02010 471486 472274 - DNAse gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02010 BOBLI757_RS02015 BOBLI757_403 BOBLI757_RS02015 472324 473298 - hypothetical protein gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02015 BOBLI757_RS02020 BOBLI757_404 BOBLI757_RS02020 473301 473948 - thymidylate kinase gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02020 BOBLI757_RS02025 BOBLI757_405 BOBLI757_RS02025 474119 474928 - 4-amino-4-deoxychorismate lyase gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02025 BOBLI757_RS02030 BOBLI757_406 BOBLI757_RS02030 475124 475360 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02030 BOBLI757_RS02035 BOBLI757_407 fabG fabG 475477 476211 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02035 BOBLI757_RS02040 BOBLI757_408 BOBLI757_RS02040 476227 477156 - malonyl CoA-ACP transacylase gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02040 BOBLI757_RS02045 BOBLI757_409 BOBLI757_RS02045 477178 478131 - 3-oxoacyl-ACP synthase FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02045 BOBLI757_RS02050 BOBLI757_410 BOBLI757_RS02050 478143 479150 - phosphate acyltransferase gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02050 BOBLI757_RS02055 BOBLI757_411 rpmF rpmF 479201 479374 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02055 BOBLI757_RS02060 BOBLI757_412 BOBLI757_RS02060 480229 481188 - 23S rRNA pseudouridylate synthase catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02060 BOBLI757_RS02065 BOBLI757_RS02065 BOBLI757_RS02065 481790 483325 + ribonuclease E gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02065 BOBLI757_RS02070 BOBLI757_414 BOBLI757_RS02070 484366 485295 + lipid A biosynthesis lauroyl acyltransferase Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02070 BOBLI757_RS02075 BOBLI757_415 BOBLI757_RS02075 485704 485785 - tRNA-Leu tRNA gene412 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02075 BOBLI757_RS02080 BOBLI757_416 BOBLI757_RS02080 485806 485877 - tRNA-Cys tRNA gene413 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02080 BOBLI757_RS02085 BOBLI757_417 BOBLI757_RS02085 486349 486900 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02085 BOBLI757_RS02090 BOBLI757_418 BOBLI757_RS02090 487731 487803 - tRNA-Lys tRNA gene415 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02090 BOBLI757_RS02095 BOBLI757_419 BOBLI757_RS02095 488092 488177 - tRNA-Ser tRNA gene416 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02095 BOBLI757_RS02100 BOBLI757_420 BOBLI757_RS02100 489064 489381 + heat-shock protein HspQ gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02100 BOBLI757_RS02105 BOBLI757_421 BOBLI757_RS02105 490784 491305 + 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02105 BOBLI757_RS02110 BOBLI757_422 BOBLI757_RS02110 491900 492682 + enoyl-ACP reductase Catalyzes a key regulatory step in fatty acid biosynthesis gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02110 BOBLI757_RS02115 BOBLI757_423 BOBLI757_RS02115 492834 493472 + MBL fold metallo-hydrolase gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02115 BOBLI757_RS02120 BOBLI757_424 BOBLI757_RS02120 493585 494775 - aromatic amino acid aminotransferase gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02120 BOBLI757_RS02125 BOBLI757_425 BOBLI757_RS02125 494956 496356 - asparaginyl-tRNA synthetase gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02125 BOBLI757_RS02130 BOBLI757_427 cysB cysB 498288 499262 - CysB family transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02130 BOBLI757_RS02145 BOBLI757_429 BOBLI757_RS02145 503147 504709 + anthranilate synthase component I with component II%2C the glutamine amidotransferase%2C catalyzes the formation of anthranilate from chorismate and glutamine gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02145 BOBLI757_RS02150 BOBLI757_430 BOBLI757_RS02150 504709 505302 + anthranilate synthase subunit II gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02150 BOBLI757_RS02155 BOBLI757_431 BOBLI757_RS02155 505317 506339 + anthranilate phosphoribosyltransferase gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02155 BOBLI757_RS02160 BOBLI757_432 BOBLI757_RS02160 506329 507705 + indole-3-glycerol phosphate synthase monomeric bifunctional protein%3B functions in tryptophan biosynthesis pathway%3B phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02160 BOBLI757_RS02165 BOBLI757_433 BOBLI757_RS02165 507760 508953 + tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02165 BOBLI757_RS02170 BOBLI757_434 BOBLI757_RS02170 508946 509758 + tryptophan synthase subunit alpha gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02170 BOBLI757_RS02175 BOBLI757_435 BOBLI757_RS02175 510384 511112 + hypothetical protein gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02175 BOBLI757_RS02180 BOBLI757_436 cls cls 511762 513228 + cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02180 BOBLI757_RS02185 BOBLI757_437 BOBLI757_RS02185 513730 514311 - thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02185 BOBLI757_RS02190 BOBLI757_438 BOBLI757_RS02190 514905 515312 + transcriptional regulator gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02190 BOBLI757_RS02195 BOBLI757_439 BOBLI757_RS02195 516503 517414 - UTP--glucose-1-phosphate uridylyltransferase together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase%2C an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate%3B regulates cellular levels of UDP-glucose gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02195 BOBLI757_RS02200 BOBLI757_440 BOBLI757_RS02200 517876 518688 + hypothetical protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02200 BOBLI757_RS02205 BOBLI757_441 BOBLI757_RS02205 519448 521295 + signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02205 BOBLI757_RS02210 BOBLI757_442 BOBLI757_RS02210 521868 522866 + glyceraldehyde-3-phosphate dehydrogenase gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02210 BOBLI757_RS02215 BOBLI757_443 BOBLI757_RS02215 523730 524242 + disulfide bond formation protein B disulfide oxidoreductase%3B integral membrane protein%3B required for perioplasmic disulfide bond formation%3B oxidizes DsbA protein gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02215 BOBLI757_RS02220 BOBLI757_444 BOBLI757_RS02220 524740 525423 + hypothetical protein gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02220 BOBLI757_RS02225 BOBLI757_445 BOBLI757_RS02225 525449 526261 + cell division inhibitor MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02225 BOBLI757_RS02230 BOBLI757_RS02230 BOBLI757_RS02230 526266 526580 + hypothetical protein gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02230 BOBLI757_RS02235 BOBLI757_447 BOBLI757_RS02235 526698 527321 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02235 BOBLI757_RS02240 BOBLI757_448 BOBLI757_RS02240 527629 528996 + aminodeoxychorismate synthase gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02240 BOBLI757_RS02245 BOBLI757_449 BOBLI757_RS02245 529242 530786 - membrane protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02245 BOBLI757_RS02250 BOBLI757_450 BOBLI757_RS02250 531232 532197 + PTS mannose transporter subunit IIAB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02250 BOBLI757_RS02255 BOBLI757_451 BOBLI757_RS02255 532222 533022 + PTS mannose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02255 BOBLI757_RS02260 BOBLI757_452 BOBLI757_RS02260 533038 533892 + PTS mannose transporter subunit IID hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02260 BOBLI757_RS02265 BOBLI757_453 BOBLI757_RS02265 534140 534349 - cold-shock protein gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02265 BOBLI757_RS02270 BOBLI757_454 BOBLI757_RS02270 534865 535779 - heat-shock protein HtpX metalloprotease gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02270 BOBLI757_RS02275 BOBLI757_455 BOBLI757_RS02275 536730 538226 - glucose-6-phosphate dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02275 BOBLI757_RS02280 BOBLI757_RS02280 BOBLI757_RS02280 539489 540742 - hypothetical protein gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02280 BOBLI757_RS02285 BOBLI757_457 BOBLI757_RS02285 541546 543300 - aspartyl-tRNA synthetase gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02285 BOBLI757_RS02290 BOBLI757_458 BOBLI757_RS02290 543863 545599 + arginyl-tRNA synthetase gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02290 BOBLI757_RS02295 BOBLI757_459 BOBLI757_RS02295 545671 547227 - membrane protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02295 BOBLI757_RS02300 BOBLI757_460 BOBLI757_RS02300 547905 549113 + multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02300 BOBLI757_RS02305 BOBLI757_461 BOBLI757_RS02305 549445 549535 + tRNA-Ser tRNA gene458 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02305 BOBLI757_RS02310 BOBLI757_462 BOBLI757_RS02310 549645 549732 - tRNA-Ser tRNA gene459 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02310 BOBLI757_RS02315 BOBLI757_463 BOBLI757_RS02315 549966 550038 + tRNA-Asn tRNA gene460 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02315 BOBLI757_RS02320 BOBLI757_464 BOBLI757_RS02320 550425 551414 - arabinose 5-phosphate isomerase gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02320 BOBLI757_RS02325 BOBLI757_465 BOBLI757_RS02325 551916 552239 - hypothetical protein gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02325 BOBLI757_RS02330 BOBLI757_466 BOBLI757_RS02330 552502 553944 + hypothetical protein gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02330 BOBLI757_RS02335 BOBLI757_467 hisG hisG 554338 555237 + ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02335 BOBLI757_RS02340 BOBLI757_468 hisD hisD 555243 556562 + histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02340 BOBLI757_RS02345 BOBLI757_469 BOBLI757_RS02345 556552 557625 + histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02345 BOBLI757_RS02350 BOBLI757_470 BOBLI757_RS02350 557644 558723 + imidazoleglycerol-phosphate dehydratase catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02350 BOBLI757_RS02355 BOBLI757_471 BOBLI757_RS02355 558723 559319 + hypothetical protein gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02355 BOBLI757_RS02360 BOBLI757_472 BOBLI757_RS02360 559327 560070 + 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02360 BOBLI757_RS02365 BOBLI757_473 BOBLI757_RS02365 560052 560825 + imidazole glycerol phosphate synthase gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02365 BOBLI757_RS02370 BOBLI757_474 BOBLI757_RS02370 560822 561430 + phosphoribosyl-ATP pyrophosphatase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02370 BOBLI757_RS02375 BOBLI757_475 BOBLI757_RS02375 561549 562955 - 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02375 BOBLI757_RS02380 BOBLI757_476 metG metG 563701 565350 + methionine--tRNA ligase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02380 BOBLI757_RS02385 BOBLI757_477 folE folE 565746 566399 - GTP cyclohydrolase involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02385 BOBLI757_RS02390 BOBLI757_478 BOBLI757_RS02390 567014 567301 + hypothetical protein gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02390 BOBLI757_RS02395 BOBLI757_479 BOBLI757_RS02395 567533 568639 - D-alanine--D-alanine ligase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02395 BOBLI757_RS02400 BOBLI757_480 BOBLI757_RS02400 568842 570014 - membrane protein gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02400 BOBLI757_RS02405 BOBLI757_481 BOBLI757_RS02405 570574 573120 - DNA gyrase subunit A gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02405 BOBLI757_RS02410 BOBLI757_482 BOBLI757_RS02410 573310 574095 + 3-demethylubiquinone-9 3-methyltransferase Involved in ubiquinone biosynthesis gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02410 BOBLI757_RS02415 BOBLI757_483 BOBLI757_RS02415 574514 576796 + ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02415 BOBLI757_RS02420 BOBLI757_484 BOBLI757_RS02420 576856 577989 + ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02420 BOBLI757_RS02425 BOBLI757_485 BOBLI757_RS02425 578006 578269 + hypothetical protein gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02425 BOBLI757_RS02430 BOBLI757_486 BOBLI757_RS02430 578341 579795 - NADH:ubiquinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02430 BOBLI757_RS02435 BOBLI757_487 BOBLI757_RS02435 579840 581348 - NADH:ubiquinone oxidoreductase subunit M gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02435 BOBLI757_RS02440 BOBLI757_488 BOBLI757_RS02440 581426 583273 - NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02440 BOBLI757_RS02445 BOBLI757_489 BOBLI757_RS02445 583270 583572 - NADH:ubiquinone oxidoreductase subunit K gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02445 BOBLI757_RS02450 BOBLI757_490 BOBLI757_RS02450 583645 584133 - NADH:ubiquinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02450 BOBLI757_RS02455 BOBLI757_491 BOBLI757_RS02455 584177 584731 - NADH dehydrogenase gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02455 BOBLI757_RS02460 BOBLI757_492 BOBLI757_RS02460 584746 585723 - NADH:ubiquinone oxidoreductase gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02460 BOBLI757_RS02465 BOBLI757_493 BOBLI757_RS02465 585720 588467 - NADH dehydrogenase Catalyzes the transfer of electrons from NADH to quinone gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02465 BOBLI757_RS02470 BOBLI757_494 BOBLI757_RS02470 588633 589958 - NADH dehydrogenase part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02470 BOBLI757_RS02475 BOBLI757_495 BOBLI757_RS02475 589955 590437 - NADH dehydrogenase Catalyzes the transfer of electrons from NADH to quinone gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02475 BOBLI757_RS02480 BOBLI757_496 BOBLI757_RS02480 590491 592242 - NADH:ubiquinone oxidoreductase NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02480 BOBLI757_RS02485 BOBLI757_497 BOBLI757_RS02485 592420 593094 - NADH dehydrogenase gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02485 BOBLI757_RS02490 BOBLI757_498 BOBLI757_RS02490 593266 593664 - hypothetical protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02490 BOBLI757_RS02495 BOBLI757_499 BOBLI757_RS02495 594312 595595 - bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02495 BOBLI757_RS02500 BOBLI757_500 BOBLI757_RS02500 595659 596522 - acetyl-CoA carboxylase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02500 BOBLI757_RS02505 BOBLI757_501 truA truA 596762 597556 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02505 BOBLI757_RS02515 BOBLI757_503 BOBLI757_RS02515 599169 600380 - 3-oxoacyl-ACP synthase FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02515 BOBLI757_RS02520 BOBLI757_504 BOBLI757_RS02520 600867 601778 + hypothetical protein gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02520 BOBLI757_RS02525 BOBLI757_505 BOBLI757_RS02525 601870 602937 + chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02525 BOBLI757_RS02530 BOBLI757_507 BOBLI757_RS02530 603741 604994 - manganese transport protein MntH gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02530 BOBLI757_RS02535 BOBLI757_508 gltX gltX 605483 606898 - glutamyl-tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02535 BOBLI757_RS02540 BOBLI757_509 BOBLI757_RS02540 607081 607154 + tRNA-Val tRNA gene505 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02540 BOBLI757_RS02545 BOBLI757_510 BOBLI757_RS02545 607207 607279 + tRNA-Lys tRNA gene506 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02545 BOBLI757_RS02550 BOBLI757_511 ligA ligA 607446 609488 - NAD-dependent DNA ligase LigA this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02550 BOBLI757_RS02555 BOBLI757_512 BOBLI757_RS02555 610260 611210 + cysteine synthase gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02555 BOBLI757_RS02560 BOBLI757_513 BOBLI757_RS02560 611460 611717 + PTS sugar transporter gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02560 BOBLI757_RS02565 BOBLI757_514 BOBLI757_RS02565 611772 613499 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02565 BOBLI757_RS02570 BOBLI757_515 BOBLI757_RS02570 613761 614831 - sulfate/thiosulfate transporter subunit gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02570 BOBLI757_RS02575 BOBLI757_516 cysW cysW 614853 615695 - sulfate/thiosulfate transporter permease subunit Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02575 BOBLI757_RS02580 BOBLI757_517 BOBLI757_RS02580 615695 616528 - sulfate/thiosulfate transporter subunit gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02580 BOBLI757_RS02585 BOBLI757_518 BOBLI757_RS02585 616509 617528 - thiosulfate transporter subunit gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02585 BOBLI757_RS02590 BOBLI757_519 BOBLI757_RS02590 618920 619873 + transaldolase gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02590 BOBLI757_RS02595 BOBLI757_520 BOBLI757_RS02595 619888 621894 + transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02595 BOBLI757_RS02600 BOBLI757_521 BOBLI757_RS02600 622240 623373 + succinyl-diaminopimelate desuccinylase gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02600 BOBLI757_RS02605 BOBLI757_522 BOBLI757_RS02605 623622 624497 - 4-hydroxy-tetrahydrodipicolinate synthase gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02605 BOBLI757_RS02610 BOBLI757_523 upp upp 625468 626094 - uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02610 BOBLI757_RS02615 BOBLI757_524 BOBLI757_RS02615 627234 627851 - urease accessory protein UreG gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02615 BOBLI757_RS02620 BOBLI757_525 BOBLI757_RS02620 627901 628593 - hypothetical protein gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02620 BOBLI757_RS02625 BOBLI757_526 ureC ureC 628927 630630 - urease subunit alpha ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02625 BOBLI757_RS02630 BOBLI757_527 ureB ureB 630627 630944 - urease subunit beta ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta)%3B in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity%2C optimum growth%2C resistance to low-pH killing in-vitro and persistence in-vivo%2C while the other operon does not seem to be active gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02630 BOBLI757_RS02635 BOBLI757_528 ureA ureA 630976 631278 - urease subunit gamma UreA%2C with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide%3B nickel metalloenzyme%3B accessory proteins UreD%2C UreE%2C UreF%2C and UreG are necessary for assembly of the metallocenter gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02635 BOBLI757_RS02640 BOBLI757_529 BOBLI757_RS02640 631297 632106 - hypothetical protein gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02640 BOBLI757_RS02645 BOBLI757_530 guaA guaA 632418 634025 - GMP synthase contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02645 BOBLI757_RS02650 BOBLI757_531 BOBLI757_RS02650 634126 635589 - inosine-5-monophosphate dehydrogenase gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02650 BOBLI757_RS02655 BOBLI757_532 BOBLI757_RS02655 636247 637851 + malate:quinone oxidoreductase gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02655 BOBLI757_RS02660 BOBLI757_533 BOBLI757_RS02660 637871 639265 - GTP-binding protein Der gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02660 BOBLI757_RS02665 BOBLI757_534 BOBLI757_RS02665 639343 640467 - hypothetical protein gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02665 BOBLI757_RS02670 BOBLI757_535 hisS hisS 640762 642048 - histidine--tRNA ligase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02670 BOBLI757_RS02675 BOBLI757_536 BOBLI757_RS02675 642060 643202 - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02675 BOBLI757_RS02680 BOBLI757_537 BOBLI757_RS02680 643520 643933 - hypothetical protein gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02680 BOBLI757_RS02685 BOBLI757_538 BOBLI757_RS02685 644491 645576 - ribosomal RNA large subunit methyltransferase N 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02685 BOBLI757_RS02690 BOBLI757_539 BOBLI757_RS02690 645638 646057 - nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02690 BOBLI757_RS02695 BOBLI757_540 BOBLI757_RS02695 646313 647488 - cysteine desulfurase catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02695 BOBLI757_RS02700 BOBLI757_541 BOBLI757_RS02700 648268 649080 + hypothetical protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02700 BOBLI757_RS02705 BOBLI757_542 BOBLI757_RS02705 649155 650396 - serine hydroxymethyltransferase gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02705 BOBLI757_RS02710 BOBLI757_543 BOBLI757_RS02710 650809 651315 - hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02710 BOBLI757_RS02715 BOBLI757_544 acpS acpS 651663 652043 - 4'-phosphopantetheinyl transferase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02715 BOBLI757_RS02720 BOBLI757_RS02720 BOBLI757_RS02720 652043 652799 - hypothetical protein gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02720 BOBLI757_RS02725 BOBLI757_546 BOBLI757_RS02725 653043 653942 - GTPase Era gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02725 BOBLI757_RS02730 BOBLI757_547 rnc rnc 653935 654627 - ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02730 BOBLI757_RS02735 BOBLI757_548 BOBLI757_RS02735 654796 655794 - hypothetical protein gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02735 BOBLI757_RS02740 BOBLI757_549 BOBLI757_RS02740 655809 657608 - elongation factor 4 gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02740 BOBLI757_RS02745 BOBLI757_550 BOBLI757_RS02745 658137 658829 + uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02745 BOBLI757_RS02750 BOBLI757_551 BOBLI757_RS02750 658954 659553 - heat shock protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02750 BOBLI757_RS02755 BOBLI757_552 ppnK ppnK 659677 660555 + inorganic polyphosphate kinase catalyzes the phosphorylation of NAD to NADP gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02755 BOBLI757_RS02760 BOBLI757_553 BOBLI757_RS02760 661152 661589 - hypothetical protein gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02760 BOBLI757_RS02765 BOBLI757_554 BOBLI757_RS02765 661698 662195 + SsrA-binding protein gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02765 BOBLI757_RS02770 BOBLI757_556 BOBLI757_RS02770 662874 663203 + multidrug transporter gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02770 BOBLI757_RS02775 BOBLI757_557 pssA pssA 663309 664700 + phosphatidylserine synthase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02775 BOBLI757_RS02780 BOBLI757_558 BOBLI757_RS02780 664757 667693 - 23S ribosomal RNA rRNA gene553 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02780 BOBLI757_RS02785 BOBLI757_559 BOBLI757_RS02785 667902 667974 - tRNA-Glu tRNA gene554 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02785 BOBLI757_RS02790 BOBLI757_560 BOBLI757_RS02790 668115 669714 - 16S ribosomal RNA rRNA gene555 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02790 BOBLI757_RS02795 BOBLI757_561 purH purH 670286 671884 + phosphoribosylaminoimidazolecarboxamide formyltransferase involved in de novo purine biosynthesis gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02795 BOBLI757_RS02800 BOBLI757_562 BOBLI757_RS02800 672062 672334 - DNA-binding protein gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02800 BOBLI757_RS02805 BOBLI757_563 BOBLI757_RS02805 672577 676818 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02805 BOBLI757_RS02810 BOBLI757_564 rpoB rpoB 676896 680924 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02810 BOBLI757_RS02815 BOBLI757_565 BOBLI757_RS02815 681161 681532 - 50S ribosomal protein L7/L12 gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02815 BOBLI757_RS02820 BOBLI757_566 BOBLI757_RS02820 681602 682093 - hypothetical protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02820 BOBLI757_RS02825 BOBLI757_567 BOBLI757_RS02825 682293 682991 - 50S ribosomal protein L1 gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02825 BOBLI757_RS02830 BOBLI757_568 BOBLI757_RS02830 682993 683421 - 50S ribosomal protein L11 gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02830 BOBLI757_RS02835 BOBLI757_569 nusG nusG 683595 684140 - transcription antiterminator NusG Modulates Rho-dependent transcription termination gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02835 BOBLI757_RS02840 BOBLI757_570 BOBLI757_RS02840 684144 684518 - hypothetical protein gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02840 BOBLI757_RS02845 BOBLI757_571 tuf tuf 684632 685816 - elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02845 BOBLI757_RS02850 BOBLI757_572 fusA fusA 685904 688006 - elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02850 BOBLI757_RS02855 BOBLI757_573 BOBLI757_RS02855 688162 688635 - 30S ribosomal protein S7 gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02855 BOBLI757_RS02860 BOBLI757_574 BOBLI757_RS02860 688772 689146 - 30S ribosomal protein S12 gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02860 BOBLI757_RS02865 BOBLI757_575 BOBLI757_RS02865 690457 691044 - anthranilate synthase component II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02865 BOBLI757_RS02870 BOBLI757_576 BOBLI757_RS02870 691291 692304 - hypothetical protein gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02870 BOBLI757_RS02875 BOBLI757_577 BOBLI757_RS02875 692754 693419 - ribulose-phosphate 3-epimerase gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02875 BOBLI757_RS02880 BOBLI757_578 aroB aroB 694137 695225 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02880 BOBLI757_RS02885 BOBLI757_579 aroK aroK 695272 695790 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02885 BOBLI757_RS02890 BOBLI757_RS02890 nudE nudE 696846 697413 - adenosine nucleotide hydrolase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02890 BOBLI757_RS02895 BOBLI757_581 BOBLI757_RS02895 698009 698590 + Fe/S biogenesis protein NfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02895 BOBLI757_RS02900 BOBLI757_582 BOBLI757_RS02900 698753 699865 - aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02900 BOBLI757_RS02905 BOBLI757_583 BOBLI757_RS02905 700078 700671 + antibiotic transporter gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02905 BOBLI757_RS02910 BOBLI757_584 BOBLI757_RS02910 700740 701558 - hydrolase gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02910 BOBLI757_RS02915 BOBLI757_585 BOBLI757_RS02915 702249 703199 - magnesium transporter CorA responsible for the influx of magnesium ions gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02915 BOBLI757_RS02920 BOBLI757_RS02920 BOBLI757_RS02920 704625 704855 - hypothetical protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02920 BOBLI757_RS02925 BOBLI757_588 dapF dapF 707043 707873 - diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02925 BOBLI757_RS02930 BOBLI757_589 hemC hemC 709363 710268 + porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02930 BOBLI757_RS02935 BOBLI757_590 hemD hemD 710317 711063 + uroporphyrinogen-III synthase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02935 BOBLI757_RS02940 BOBLI757_591 BOBLI757_RS02940 711313 711386 - tRNA-Pro tRNA gene585 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02940 BOBLI757_RS02945 BOBLI757_593 BOBLI757_RS02945 711611 711686 - tRNA-His tRNA gene586 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02945 BOBLI757_RS02950 BOBLI757_594 BOBLI757_RS02950 711780 711854 - tRNA-Arg tRNA gene587 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02950 BOBLI757_RS02955 BOBLI757_595 rho rho 712425 713684 - transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02955 BOBLI757_RS02960 BOBLI757_596 trxA trxA 713977 714309 - thioredoxin gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02960 BOBLI757_RS02965 BOBLI757_597 BOBLI757_RS02965 714993 716465 - ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02965 BOBLI757_RS02970 BOBLI757_598 BOBLI757_RS02970 716850 718706 - dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02970 BOBLI757_RS02975 BOBLI757_599 BOBLI757_RS02975 718769 719695 - branched-chain amino acid aminotransferase gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02975 BOBLI757_RS02980 BOBLI757_600 BOBLI757_RS02980 719774 720019 - hypothetical protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02980 BOBLI757_RS02985 BOBLI757_601 BOBLI757_RS02985 720023 721666 - acetolactate synthase catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02985 BOBLI757_RS02990 BOBLI757_602 BOBLI757_RS02990 722941 723016 - tRNA-Trp tRNA gene595 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02990 BOBLI757_RS02995 BOBLI757_603 BOBLI757_RS02995 723035 723108 - tRNA-Asp tRNA gene596 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS02995 BOBLI757_RS03000 BOBLI757_604 BOBLI757_RS03000 723125 723197 - tRNA-Ala tRNA gene597 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03000 BOBLI757_RS03005 BOBLI757_605 BOBLI757_RS03005 723412 724230 - hypothetical protein gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03005 BOBLI757_RS03010 BOBLI757_606 metF metF 724467 725366 - 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03010 BOBLI757_RS03015 BOBLI757_607 BOBLI757_RS03015 726153 727319 - cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03015 BOBLI757_RS03020 BOBLI757_608 rpmE rpmE 727474 727683 - 50S ribosomal protein L31 RpmE%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03020 BOBLI757_RS03025 BOBLI757_609 BOBLI757_RS03025 729039 729788 + ferredoxin-NADP reductase gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03025 BOBLI757_RS03030 BOBLI757_610 BOBLI757_RS03030 730086 730856 + triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03030 BOBLI757_RS03035 BOBLI757_611 BOBLI757_RS03035 731132 732094 - 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03035 BOBLI757_RS03040 BOBLI757_612 cysE cysE 732847 733584 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03040 BOBLI757_RS03045 BOBLI757_613 BOBLI757_RS03045 733650 734651 - glycerol-3-phosphate dehydrogenase gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03045 BOBLI757_RS03050 BOBLI757_614 BOBLI757_RS03050 734648 735127 - preprotein translocase subunit SecB molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm%3B in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03050 BOBLI757_RS03055 BOBLI757_615 BOBLI757_RS03055 735206 735460 - hypothetical protein gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03055 BOBLI757_RS03060 BOBLI757_RS03060 BOBLI757_RS03060 735505 735813 - hypothetical protein gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03060 BOBLI757_RS03065 BOBLI757_617 rfaD rfaD 736758 737714 + ADP-L-glycero-D-manno-heptose-6-epimerase catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03065 BOBLI757_RS03070 BOBLI757_618 BOBLI757_RS03070 737754 738812 + ADP-heptose--LPS heptosyltransferase catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03070 BOBLI757_RS03075 BOBLI757_619 BOBLI757_RS03075 738827 739796 + hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03075 BOBLI757_RS03080 BOBLI757_620 BOBLI757_RS03080 739990 741264 + 3-deoxy-D-manno-octulosonic acid transferase catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03080 BOBLI757_RS03085 BOBLI757_621 BOBLI757_RS03085 741320 742036 + LPS biosynthesis protein gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03085 BOBLI757_RS03090 BOBLI757_622 BOBLI757_RS03090 742559 743368 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03090 BOBLI757_RS03095 BOBLI757_623 rpmG rpmG 743460 743630 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03095 BOBLI757_RS03100 BOBLI757_624 rpmB rpmB 743642 743890 - 50S ribosomal protein L28 required for 70S ribosome assembly gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03100 BOBLI757_RS03105 BOBLI757_625 BOBLI757_RS03105 745395 745853 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03105 BOBLI757_RS03110 BOBLI757_626 BOBLI757_RS03110 746212 747060 + hypothetical protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03110 BOBLI757_RS03115 BOBLI757_627 BOBLI757_RS03115 747727 748152 + MarR family transcriptional regulator gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03115 BOBLI757_RS03120 BOBLI757_628 BOBLI757_RS03120 748434 749048 + guanylate kinase gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03120 BOBLI757_RS03125 BOBLI757_629 rpoZ rpoZ 749118 749315 + DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly%3B latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03125 BOBLI757_RS03130 BOBLI757_631 BOBLI757_RS03130 751277 754087 - DNA polymerase I has 3'-5' exonuclease%2C 5'-3' exonuclease and 5'-3'polymerase activities%2C primarily functions to fill gaps during DNA replication and repair gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03130 BOBLI757_RS03135 BOBLI757_632 BOBLI757_RS03135 754480 755103 - protein disulfide isomerase gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03135 BOBLI757_RS03140 BOBLI757_633 BOBLI757_RS03140 755552 757069 - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03140 BOBLI757_RS03145 BOBLI757_634 ubiB ubiB 757246 758877 - ubiquinone biosynthesis protein UbiB an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone%3B functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis%3B similar to eukaryotic proteins that exhibit kinase functions gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03145 BOBLI757_RS03150 BOBLI757_635 ubiE ubiE 759375 760133 - ubiquinone biosynthesis methyltransferase UbiE Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone and menaquinone gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03150 BOBLI757_RS03155 BOBLI757_636 BOBLI757_RS03155 760275 761792 - hypothetical protein gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03155 BOBLI757_RS03160 BOBLI757_637 BOBLI757_RS03160 762789 765092 - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03160 BOBLI757_RS03165 BOBLI757_638 BOBLI757_RS03165 765440 766297 - RNA polymerase factor sigma-32 binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03165 BOBLI757_RS03170 BOBLI757_639 BOBLI757_RS03170 766892 767878 - signal recognition particle-docking protein FtsY gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03170 BOBLI757_RS03175 BOBLI757_640 BOBLI757_RS03175 768297 768896 + hypothetical protein gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03175 BOBLI757_RS03180 BOBLI757_641 BOBLI757_RS03180 771325 772218 - homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03180 BOBLI757_RS03185 BOBLI757_642 BOBLI757_RS03185 772623 772697 - tRNA-Ile tRNA gene634 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03185 BOBLI757_RS03195 BOBLI757_RS03195 BOBLI757_RS03195 15828 16010 + hypothetical protein gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03195 BOBLI757_RS03200 BOBLI757_RS03200 BOBLI757_RS03200 215686 216063 + hypothetical protein gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03200 BOBLI757_RS03205 BOBLI757_232 secD secD 264106 265597 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03205 BOBLI757_RS03210 BOBLI757_342 BOBLI757_RS03210 403462 404241 + hypothetical protein gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03210 BOBLI757_RS03215 BOBLI757_389 BOBLI757_RS03215 455030 457195 - hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03215 BOBLI757_RS03220 BOBLI757_RS03220 BOBLI757_RS03220 499790 500083 - hypothetical protein gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03220 BOBLI757_RS03225 BOBLI757_RS03225 BOBLI757_RS03225 500236 500454 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03225 BOBLI757_RS03230 BOBLI757_RS03230 BOBLI757_RS03230 598318 598521 - hypothetical protein gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=BOBLI757_RS03230