locus-tag	class	description
GN161_RS00010	ENOG4105M8F	Biopolymer transport protein exbD tolR
GN161_RS00015	ENOG4105E02	MotA TolQ exbB proton channel
GN161_RS00020	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
GN161_RS00025	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
GN161_RS00030	ENOG4105C7S	Dehydrogenase
GN161_RS00035	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GN161_RS00040	ENOG4105E33	succinate dehydrogenase
GN161_RS00045	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
GN161_RS00050	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
GN161_RS00055	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
GN161_RS00060	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
GN161_RS00065	ENOG4105EV9	Alpha Beta Hydrolase
GN161_RS00070	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
GN161_RS00075	ENOG4105CX6	glutaminyL-tRNA synthetase
GN161_RS00080	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GN161_RS00085	ENOG4105CE4	GlcNAc 6-P deacetylase
GN161_RS00105	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
GN161_RS00110	ENOG4105C9A	Phoh family
GN161_RS00115	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GN161_RS00120	ENOG4108JU5	Magnesium and cobalt efflux protein
GN161_RS00125	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GN161_RS00130	ENOG4105C8T	Leucyl-tRNA synthetase
GN161_RS00145	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
GN161_RS00150	ENOG4105CJN	penicillin-binding protein
GN161_RS00155	ENOG4105CNI	cell division protein FtsW
GN161_RS00160	ENOG4105DXC	membrane
GN161_RS00170	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GN161_RS00175	ENOG4105C8N	cysteinyl-tRNA synthetase
GN161_RS00180	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
GN161_RS00185	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GN161_RS00190	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GN161_RS00195	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GN161_RS00205	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GN161_RS00210	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GN161_RS00215	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GN161_RS00220	ENOG4105VQ7	Rod shape-determining protein MreD
GN161_RS00225	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
GN161_RS00230	ENOG4105DFF	Rod shape-determining protein mreb
GN161_RS00235	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GN161_RS00240	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
GN161_RS00245	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GN161_RS00255	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GN161_RS00260	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GN161_RS00265	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GN161_RS00270	ENOG4105C0B	DNA polymerase III (alpha subunit)
GN161_RS00275	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GN161_RS00280	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN161_RS00285	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN161_RS00290	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GN161_RS00295	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN161_RS00300	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
GN161_RS00305	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GN161_RS00310	ENOG4105DZP	Membrane-associated zinc metalloprotease
GN161_RS00315	ENOG4105KNE	Phosphatidate cytidylyltransferase
GN161_RS00320	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GN161_RS00325	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
GN161_RS00330	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GN161_RS00335	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GN161_RS00340	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GN161_RS00345	ENOG4105CE9	30S ribosomal protein S2
GN161_RS00350	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
GN161_RS00355	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GN161_RS00360	ENOG4107QKA	exodeoxyribonuclease V beta
GN161_RS00365	ENOG4107QYX	exodeoxyribonuclease v alpha
GN161_RS00370	ENOG4105DSY	exodeoxyribonuclease V, gamma
GN161_RS00375	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GN161_RS00380	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GN161_RS00385	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GN161_RS00390	ENOG4105CRK	lysyL-tRNA synthetase
GN161_RS00395	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
GN161_RS00400	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GN161_RS00410	ENOG4105D0A	hydroxylase
GN161_RS00415	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
GN161_RS00420	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
GN161_RS00425	ENOG4105E66	phosphoriboisomerase A
GN161_RS00430	ENOG4105D2N	Aldolase
GN161_RS00435	ENOG4105BZA	Phosphoglycerate kinase
GN161_RS00440	ENOG4105CYW	agmatinase
GN161_RS00445	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GN161_RS00450	ENOG4108UJU	UPF0301 protein
GN161_RS00455	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GN161_RS00460	ENOG4105CEN	a g-specific adenine glycosylase
GN161_RS00465	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
GN161_RS00470	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
GN161_RS00475	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GN161_RS00485	ENOG4105E2S	oxidase) subunit II
GN161_RS00490	ENOG4105BZ9	Cytochrome C oxidase, subunit I
GN161_RS00495	ENOG4105CCU	oxidase (Subunit III)
GN161_RS00500	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GN161_RS00505	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GN161_RS00510	ENOG4107RDB	Major Facilitator
GN161_RS00515	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
GN161_RS00520	ENOG4105CTB	Polyprenyl synthetase
GN161_RS00525	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GN161_RS00530	ENOG4108ZAI	phosphatidylglycerophosphatase a
GN161_RS00535	ENOG4107YIM	Involved in the transcription termination process (By similarity)
GN161_RS00540	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GN161_RS00545	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GN161_RS00550	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GN161_RS00555	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GN161_RS00560	ENOG4105VIE	preprotein translocase, subunit YajC
GN161_RS00565	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GN161_RS00570	ENOG4105D3R	alkyl hydroperoxide reductase
GN161_RS00580	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
GN161_RS00585	ENOG4108JDX	DNA polymerase iii, epsilon subunit
GN161_RS00590	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GN161_RS00595	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GN161_RS00605	ENOG4105E2X	shikimate dehydrogenase
GN161_RS00610	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GN161_RS00615	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GN161_RS00620	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GN161_RS00625	ENOG4108ZT0	50S ribosomal protein l17
GN161_RS00630	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN161_RS00635	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GN161_RS00640	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GN161_RS00645	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GN161_RS00650	ENOG41067V7	50S ribosomal protein L36
GN161_RS00655	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
GN161_RS00660	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GN161_RS00665	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GN161_RS00670	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GN161_RS00675	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GN161_RS00680	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GN161_RS00685	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GN161_RS00690	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GN161_RS00695	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GN161_RS00700	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GN161_RS00705	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GN161_RS00710	ENOG41083MP	50s ribosomal protein l29
GN161_RS00715	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GN161_RS00720	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GN161_RS00725	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GN161_RS00730	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GN161_RS00735	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GN161_RS00740	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GN161_RS00745	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GN161_RS00750	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GN161_RS00755	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GN161_RS00760	ENOG4108UQY	Iron-storage protein
GN161_RS00785	ENOG4105CS9	pantothenic acid kinase
GN161_RS00795	ENOG4105D4A	Cell wall formation (By similarity)
GN161_RS00800	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GN161_RS00805	ENOG4105C34	Pseudouridine synthase
GN161_RS00810	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GN161_RS00820	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
GN161_RS00825	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
GN161_RS00830	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GN161_RS00835	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GN161_RS00840	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
GN161_RS00845	ENOG4105K5M	30s ribosomal protein S16
GN161_RS00850	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GN161_RS00865	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
GN161_RS00870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GN161_RS00875	ENOG4108K5P	(LipO)protein
GN161_RS00880	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GN161_RS00885	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
GN161_RS00890	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
GN161_RS00895	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
GN161_RS00900	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
GN161_RS00905	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GN161_RS00910	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GN161_RS00915	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GN161_RS00920	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
GN161_RS00925	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
GN161_RS00930	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GN161_RS00935	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
GN161_RS00940	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GN161_RS00945	ENOG4105BZ4	penicillin-binding protein
GN161_RS00950	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
GN161_RS00955	ENOG4107QSN	dihydrolipoamide acetyltransferase
GN161_RS00960	ENOG4107QN2	dihydrolipoyl dehydrogenase
GN161_RS00965	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GN161_RS00970	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GN161_RS00975	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GN161_RS00980	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GN161_RS00985	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GN161_RS00990	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GN161_RS00995	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GN161_RS01000	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
GN161_RS01005	ENOG4105DFU	Cell wall formation (By similarity)
GN161_RS01010	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
GN161_RS01015	ENOG4105CNI	cell division protein FtsW
GN161_RS01020	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GN161_RS01025	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GN161_RS01030	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
GN161_RS01035	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
GN161_RS01040	ENOG4105CJN	penicillin-binding protein
GN161_RS01050	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GN161_RS01055	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GN161_RS01060	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GN161_RS01065	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GN161_RS01070	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GN161_RS01075	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
GN161_RS01085	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GN161_RS01090	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GN161_RS01095	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
GN161_RS01100	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
GN161_RS01105	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GN161_RS01110	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GN161_RS01115	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GN161_RS01120	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GN161_RS01125	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GN161_RS01130	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
GN161_RS01135	ENOG4105DTN	riboflavin biosynthesis protein ribF
GN161_RS01140	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GN161_RS01145	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GN161_RS01150	ENOG4105CFG	Acts as a chaperone (By similarity)
GN161_RS01160	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
GN161_RS01175	ENOG4105C1J	atp-dependent rna helicase
GN161_RS01180	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GN161_RS01185	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GN161_RS01190	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GN161_RS01195	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GN161_RS01200	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GN161_RS01205	ENOG4105CHV	Transcription elongation factor NusA
GN161_RS01225	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GN161_RS01230	ENOG4105EEI	dihydropteroate synthase
GN161_RS01235	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
GN161_RS01240	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
GN161_RS01245	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GN161_RS01250	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GN161_RS01255	ENOG4105K46	50S ribosomal protein l27
GN161_RS01260	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GN161_RS01265	ENOG4105EAH	synthase
GN161_RS01270	ENOG4105F0N	pyrophosphate phospho-hydrolase
GN161_RS01275	ENOG4105MA0	exported protein
GN161_RS01285	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GN161_RS01290	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GN161_RS01295	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GN161_RS01300	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GN161_RS01305	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GN161_RS01310	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GN161_RS01315	ENOG4105EPW	hflc protein
GN161_RS01320	ENOG4107QJR	hflk protein
GN161_RS01325	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GN161_RS01335	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GN161_RS01340	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
GN161_RS01345	ENOG4105K8N	protein family UPF0079, ATPase
GN161_RS01355	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
GN161_RS01360	ENOG4105DJ4	phosphatidylserine decarboxylase
GN161_RS01365	ENOG4105EGS	Mechanosensitive ion channel
GN161_RS01370	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GN161_RS01375	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GN161_RS01380	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GN161_RS01385	ENOG4105VF7	tolerance protein
GN161_RS01395	ENOG4105C28	cystathionine
GN161_RS01400	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
GN161_RS01405	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
GN161_RS01410	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GN161_RS01415	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GN161_RS01420	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GN161_RS01425	ENOG4107ZVW	dihydroneopterin aldolase
GN161_RS01430	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GN161_RS01435	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GN161_RS01440	ENOG4105VCC	30S ribosomal protein S21
GN161_RS01445	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
GN161_RS01450	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GN161_RS01460	ENOG4106W5V	Membrane
GN161_RS01470	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GN161_RS01475	ENOG4105W4M	Transport-associated protein
GN161_RS01480	ENOG4108UJD	30S ribosomal protein S9
GN161_RS01485	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GN161_RS01495	ENOG4105C0H	protease
GN161_RS01500	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GN161_RS01505	ENOG4105VFK	BolA family
GN161_RS01510	ENOG4108P1K	Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity)
GN161_RS01520	ENOG4108IUZ	ABC transporter
GN161_RS01525	ENOG4105CC5	ABC transporter
GN161_RS01530	ENOG4105DIK	(ABC) transporter
GN161_RS01550	ENOG4108K5H	permease YjgP YjgQ family protein
GN161_RS01555	ENOG4108M8S	permease YjgP YjgQ family protein
GN161_RS01560	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GN161_RS01575	ENOG4105DBV	ornithine carbamoyltransferase
GN161_RS01580	ENOG4105KME	endoribonuclease L-psp
GN161_RS01585	ENOG4105CK2	sodium dicarboxylate symporter
GN161_RS01590	ENOG4105EEQ	Na H antiporter
GN161_RS01595	ENOG4108UUM	single-stranded DNA-binding protein
GN161_RS01600	ENOG4105CDU	Replicative dna helicase
GN161_RS01605	ENOG4105MYN	Zinc uptake regulation protein
GN161_RS01610	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
GN161_RS01615	ENOG4105CJ3	phosphate transporter
GN161_RS01620	ENOG4105DGW	oligopeptidase A
GN161_RS01625	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GN161_RS01630	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GN161_RS01635	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GN161_RS01645	ENOG4108ZNX	Heat shock protein
GN161_RS01650	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GN161_RS01655	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GN161_RS01660	ENOG4105VG0	50S ribosomal protein l34
GN161_RS01665	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GN161_RS01670	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GN161_RS01675	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GN161_RS01680	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GN161_RS01685	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GN161_RS01690	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GN161_RS01695	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GN161_RS01700	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GN161_RS01705	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GN161_RS01710	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GN161_RS01715	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GN161_RS01720	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GN161_RS01725	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GN161_RS01735	ENOG4105CVG	Homoserine O-transsuccinylase
GN161_RS01740	ENOG4107QP8	phosphohexose isomerase
GN161_RS01745	ENOG4106H78	methyltransferase
GN161_RS01750	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GN161_RS01760	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GN161_RS01765	ENOG4108I5U	Uridine phosphorylase
GN161_RS01770	ENOG4105CGY	Dna recombination protein
GN161_RS01775	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GN161_RS01780	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
GN161_RS01785	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
GN161_RS01790	ENOG4108Z33	Thiol disulfide Interchange Protein
GN161_RS01795	ENOG4105C2M	dna polymerase I
GN161_RS01800	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GN161_RS01805	ENOG4105C5F	glutamine synthetase
GN161_RS01810	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GN161_RS01815	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GN161_RS01825	ENOG4105DSJ	YicC domain protein
GN161_RS01830	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GN161_RS01835	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GN161_RS01840	ENOG4105KDC	50s ribosomal protein l28
GN161_RS01845	ENOG4105W0E	50S ribosomal protein L33
GN161_RS01850	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GN161_RS01855	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
GN161_RS01860	ENOG4105D16	lipopolysaccharide heptosyltransferase i
GN161_RS01870	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
GN161_RS01875	ENOG4107YZP	Rhodanese domain protein
GN161_RS01880	ENOG4105VW4	glutaredoxin 3
GN161_RS01885	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GN161_RS01890	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GN161_RS01895	ENOG4105D7W	serine acetyltransferase
GN161_RS01900	ENOG4105CTQ	phosphohexokinase
GN161_RS01905	ENOG4105CP7	Triose-phosphate isomerase
GN161_RS01910	ENOG4105DP0	ferredoxin-NADP reductase
GN161_RS01915	ENOG4105VFB	Binds the 23S rRNA (By similarity)
GN161_RS01920	ENOG4105C28	cystathionine
GN161_RS01925	ENOG4105SYT	Methylenetetrahydrofolate reductase
GN161_RS01930	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
GN161_RS01955	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
GN161_RS01960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GN161_RS01965	ENOG4105C01	Dihydroxy-acid dehydratase
GN161_RS01970	ENOG4105C7B	Threonine dehydratase
GN161_RS01975	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GN161_RS01980	ENOG4105K63	Thioredoxin
GN161_RS01985	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
GN161_RS02010	ENOG41076E6	Uroporphyrinogen-III Synthase
GN161_RS02015	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GN161_RS02020	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GN161_RS02025	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
GN161_RS02030	ENOG4105C4R	Atp-dependent dna helicase
GN161_RS02035	ENOG4107QUT	magnesium and cobalt transport protein CorA
GN161_RS02040	ENOG4105DQF	Hydrolase
GN161_RS02045	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
GN161_RS02050	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GN161_RS02055	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
GN161_RS02060	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
GN161_RS02065	ENOG4105D49	3-dehydroquinate synthase
GN161_RS02075	ENOG4105C31	Tryptophanyl-tRNA synthetase
GN161_RS02080	ENOG4105DDQ	anthranilate synthase
GN161_RS02085	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GN161_RS02090	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GN161_RS02095	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GN161_RS02100	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GN161_RS02105	ENOG4105PM1	preprotein translocase subunit SecE
GN161_RS02110	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
GN161_RS02115	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GN161_RS02120	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GN161_RS02125	ENOG4108VZM	50s ribosomal protein L10
GN161_RS02130	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GN161_RS02135	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN161_RS02140	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GN161_RS02145	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GN161_RS02165	ENOG4105JIM	Phosphatidylserine synthase
GN161_RS02180	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GN161_RS02185	ENOG4108Z1B	Cyclase dehydrase
GN161_RS02190	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
GN161_RS02195	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GN161_RS02200	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GN161_RS02205	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
GN161_RS02210	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GN161_RS02215	ENOG4105C3F	Signal peptidase i
GN161_RS02220	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GN161_RS02225	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GN161_RS02230	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GN161_RS02235	ENOG4108Z6B	deaminase
GN161_RS02240	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GN161_RS02255	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GN161_RS02260	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GN161_RS02265	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GN161_RS02270	ENOG4105CUT	histidyl-tRNA synthetase
GN161_RS02275	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GN161_RS02280	ENOG4105DWT	malate dehydrogenase (quinone)
GN161_RS02285	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GN161_RS02290	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GN161_RS02295	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GN161_RS02300	ENOG4108YZ9	Urea amidohydrolase subunit gamma
GN161_RS02305	ENOG4105KI2	Urea amidohydrolase subunit beta
GN161_RS02310	ENOG4105CQM	Urea amidohydrolase subunit alpha
GN161_RS02315	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
GN161_RS02320	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
GN161_RS02330	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GN161_RS02335	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GN161_RS02340	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GN161_RS02350	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GN161_RS02355	ENOG4105CV1	Transketolase (EC 2.2.1.1)
GN161_RS02360	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
GN161_RS02365	ENOG4108I5D	sulfate abc transporter
GN161_RS02370	ENOG4105ECW	sulfate abc transporter
GN161_RS02385	ENOG4105KZ7	phosphocarrier protein hpr
GN161_RS02390	ENOG4105C6T	cysteine synthase
GN161_RS02395	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GN161_RS02410	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GN161_RS02420	ENOG4105D9N	nucleoside
GN161_RS02425	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GN161_RS02435	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GN161_RS02440	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
GN161_RS02445	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GN161_RS02450	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
GN161_RS02455	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GN161_RS02460	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GN161_RS02465	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
GN161_RS02470	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GN161_RS02475	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN161_RS02480	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN161_RS02485	ENOG4105GKE	subunit e
GN161_RS02490	ENOG4107QIZ	NADH dehydrogenase
GN161_RS02495	ENOG4107R0R	NADH dehydrogenase subunit g
GN161_RS02500	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
GN161_RS02505	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN161_RS02510	ENOG4107UFS	subunit j
GN161_RS02515	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN161_RS02520	ENOG4105D65	subunit l
GN161_RS02525	ENOG4105C8S	subunit m
GN161_RS02530	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GN161_RS02535	ENOG4105XPH	Ferredoxin
GN161_RS02540	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GN161_RS02545	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GN161_RS02555	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GN161_RS02560	ENOG4105FCK	Membrane
GN161_RS02575	ENOG4105QAV	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
GN161_RS02580	ENOG4105EUJ	GTP cyclohydrolase i
GN161_RS02585	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GN161_RS02590	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
GN161_RS02595	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GN161_RS02600	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GN161_RS02605	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GN161_RS02615	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GN161_RS02620	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GN161_RS02625	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
GN161_RS02630	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GN161_RS02635	ENOG4105CJB	Exodeoxyribonuclease I
GN161_RS02640	ENOG41090HJ	UPF0265 protein
GN161_RS02645	ENOG4105C2X	Arabinose 5-phosphate isomerase
GN161_RS02665	ENOG4105EV4	Multidrug resistance protein mdtH
GN161_RS02670	ENOG4105CJR	Integral membrane protein (MviN
GN161_RS02675	ENOG4105C75	arginyL-tRNA synthetase
GN161_RS02680	ENOG4105C9M	aspartyl-trna synthetase
GN161_RS02685	ENOG4105DR5	peptidase
GN161_RS02690	ENOG4105CA9	Pyruvate kinase
GN161_RS02695	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GN161_RS02700	ENOG4105D0M	Protease HtpX homolog
GN161_RS02705	ENOG4105VEQ	Cold shock protein
GN161_RS02710	ENOG4105F3R	pts system mannose fructose sorbose family iid
GN161_RS02715	ENOG4105ETZ	PTS System
GN161_RS02720	ENOG4108EQA	pts system
GN161_RS02725	ENOG4105EE5	Membrane protein terC
GN161_RS02735	ENOG41072GX	Peptidase M22 Glycoprotease
GN161_RS02740	ENOG410810J	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GN161_RS02745	ENOG4107QMS	site-determining protein
GN161_RS02750	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GN161_RS02755	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
GN161_RS02760	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GN161_RS02765	ENOG4105D07	Signal peptide peptidase, SppA
GN161_RS02770	ENOG4105CGK	Exodeoxyribonuclease III
GN161_RS02780	ENOG4107104	thymidine kinase
GN161_RS02785	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
GN161_RS02795	ENOG4108S3I	UPF0259 membrane protein
GN161_RS02800	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GN161_RS02805	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
GN161_RS02810	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GN161_RS02815	ENOG4108I0Q	anthranilate phosphoribosyltransferase
GN161_RS02830	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
GN161_RS02835	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GN161_RS02840	ENOG4105C5X	domain protein
GN161_RS02845	ENOG4105CGF	Aromatic amino acid aminotransferase
GN161_RS02850	ENOG4105C5S	asparaginyl-tRNA synthetase
GN161_RS02855	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
GN161_RS02860	ENOG4105GSS	Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress (By similarity)
GN161_RS02865	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
GN161_RS02880	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
GN161_RS02900	ENOG4105D1S	lipid A biosynthesis
GN161_RS02910	ENOG4105EI2	Pseudouridine synthase
GN161_RS02915	ENOG4105VGS	50s ribosomal protein l32
GN161_RS02920	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
GN161_RS02925	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GN161_RS02930	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GN161_RS02935	ENOG4105CHR	reductase
GN161_RS02940	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GN161_RS02945	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
GN161_RS02950	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GN161_RS02955	ENOG4107QRG	dna polymerase iii
GN161_RS02960	ENOG4105F8V	Hydrolase, tatD family
GN161_RS02965	ENOG4105K59	histidine triad (HIT) protein
GN161_RS02970	ENOG4108WEF	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) (By similarity)
GN161_RS02975	ENOG4105D60	lipoprotein releasing system transmembrane protein
GN161_RS02980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GN161_RS02985	ENOG4105D60	lipoprotein releasing system transmembrane protein
GN161_RS02990	ENOG4107QTF	adenylosuccinate lyase
GN161_RS02995	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GN161_RS03000	ENOG4105KST	dependent repressor
GN161_RS03005	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
GN161_RS03020	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GN161_RS03025	ENOG4105C3M	thioredoxin reductase
GN161_RS03030	ENOG4105CNU	cell division protein FtsK
GN161_RS03035	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
GN161_RS03040	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GN161_RS03045	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GN161_RS03050	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GN161_RS03055	ENOG4105CAT	Cytidine monophosphate kinase
GN161_RS03060	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GN161_RS03065	ENOG4105BZ1	(ABC) transporter
GN161_RS03070	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
GN161_RS03075	ENOG4105W49	UPF0434 protein
GN161_RS03080	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GN161_RS03085	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GN161_RS03095	ENOG4105C9Q	fumarate hydratase class II
GN161_RS03100	ENOG4105CSM	endonuclease III
GN161_RS03105	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GN161_RS03110	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GN161_RS03115	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
GN161_RS03120	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
GN161_RS03125	ENOG4105M2J	Glutaredoxin
GN161_RS03130	ENOG4108R6K	riboflavin synthase, subunit alpha
GN161_RS03145	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GN161_RS03150	ENOG4105C9B	Cysteine desulfurase
GN161_RS03155	ENOG4105JRK	feS assembly protein SufD
GN161_RS03160	ENOG4105C3K	feS assembly ATPase SufC
GN161_RS03165	ENOG4105DIW	FeS assembly protein SUFB
GN161_RS03170	ENOG4108Z4V	iron-sulfur cluster assembly
GN161_RS03175	ENOG4107RMF	Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes (By similarity)
GN161_RS03180	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GN161_RS03185	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GN161_RS03190	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GN161_RS03195	ENOG41082NX	50s ribosomal protein l35
GN161_RS03200	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GN161_RS03205	ENOG4105C22	threonyL-tRNA synthetase
GN161_RS03210	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
GN161_RS03215	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GN161_RS03220	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GN161_RS03225	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
GN161_RS03230	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GN161_RS03235	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GN161_RS03240	ENOG4105C3G	gtp-binding protein
GN161_RS03245	ENOG4105HFZ	Membrane
GN161_RS03250	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
GN161_RS03255	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GN161_RS03260	ENOG4105UFD	tol-pal system protein YbgF
GN161_RS03265	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GN161_RS03270	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)