locus-tag	class	description
BTURN675_RS00005	COG0445	tRNA wobble uridine modification
BTURN675_RS00030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTURN675_RS00035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTURN675_RS00040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BTURN675_RS00045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTURN675_RS00050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTURN675_RS00055	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTURN675_RS00060	COG0706	membrane insertase activity
BTURN675_RS00065	COG0594	ribonuclease P activity
BTURN675_RS00070	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTURN675_RS00075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTURN675_RS00080	COG0592	DNA-directed DNA polymerase activity
BTURN675_RS00100	COG0752	glycyl-tRNA synthetase alpha subunit
BTURN675_RS00105	COG0751	glycine-tRNA ligase activity
BTURN675_RS00110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTURN675_RS00115	COG0339	signal peptide processing
BTURN675_RS00120	COG0306	phosphate transporter
BTURN675_RS00125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BTURN675_RS00140	COG0629	single-stranded DNA binding
BTURN675_RS00145	COG0025	NhaP-type Na H and K H
BTURN675_RS00150	COG1301	dicarboxylic acid transport
BTURN675_RS00155	COG0251	oxidation-reduction process
BTURN675_RS00160	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTURN675_RS00165	COG0525	valine-tRNA ligase activity
BTURN675_RS00175	COG0795	lipopolysaccharide-transporting ATPase activity
BTURN675_RS00180	COG0795	lipopolysaccharide-transporting ATPase activity
BTURN675_RS00200	COG1137	ATPase activity
BTURN675_RS00210	COG0271	Belongs to the BolA IbaG family
BTURN675_RS00215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTURN675_RS00220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTURN675_RS00230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTURN675_RS00235	COG2823	Periplasmic or secreted lipoprotein
BTURN675_RS00240	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTURN675_RS00245	COG0586	Pfam SNARE associated Golgi protein
BTURN675_RS00260	COG0358	DNA primase activity
BTURN675_RS00275	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTURN675_RS00280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTURN675_RS00285	COG1968	undecaprenyl-diphosphatase activity
BTURN675_RS00290	COG0617	tRNA 3'-terminal CCA addition
BTURN675_RS00295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTURN675_RS00295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BTURN675_RS00305	COG0626	cystathionine gamma-synthase activity
BTURN675_RS00315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTURN675_RS00320	COG0459	protein refolding
BTURN675_RS00325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTURN675_RS00330	COG1511	domain protein
BTURN675_RS00330	COG3264	Mechanosensitive ion channel
BTURN675_RS00335	COG0688	phosphatidylethanolamine metabolic process
BTURN675_RS00340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BTURN675_RS00350	COG0802	atpase or kinase
BTURN675_RS00360	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTURN675_RS00365	COG0330	HflC and HflK could
BTURN675_RS00370	COG0330	HflC and HflK could
BTURN675_RS00375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTURN675_RS00380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTURN675_RS00385	COG0360	Binds together with S18 to 16S ribosomal RNA
BTURN675_RS00390	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTURN675_RS00395	COG0359	binds to the 23S rRNA
BTURN675_RS00400	COG1218	3'(2'),5'-bisphosphate nucleotidase
BTURN675_RS00410	COG2911	Protein conserved in bacteria
BTURN675_RS00415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BTURN675_RS00420	COG0142	geranyltranstransferase activity
BTURN675_RS00425	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTURN675_RS00445	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BTURN675_RS00455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTURN675_RS00460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTURN675_RS00465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTURN675_RS00480	COG0195	Participates in both transcription termination and antitermination
BTURN675_RS00485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTURN675_RS00495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTURN675_RS00505	COG1185	polyribonucleotide nucleotidyltransferase activity
BTURN675_RS00510	COG0513	Belongs to the DEAD box helicase family
BTURN675_RS00520	COG0083	homoserine kinase activity
BTURN675_RS00530	COG0443	Heat shock 70 kDa protein
BTURN675_RS00535	COG0484	heat shock protein binding
BTURN675_RS00540	COG0268	Binds directly to 16S ribosomal RNA
BTURN675_RS00545	COG0196	riboflavin kinase activity
BTURN675_RS00550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTURN675_RS00555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BTURN675_RS00560	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BTURN675_RS00565	COG0505	Belongs to the CarA family
BTURN675_RS00570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTURN675_RS00575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BTURN675_RS00585	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTURN675_RS00595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTURN675_RS00600	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BTURN675_RS00605	COG0066	3-isopropylmalate dehydratase activity
BTURN675_RS00610	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTURN675_RS00620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTURN675_RS00625	COG0275	rRNA processing
BTURN675_RS00630	COG3116	cell division
BTURN675_RS00635	COG0768	penicillin binding
BTURN675_RS00640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTURN675_RS00645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTURN675_RS00650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTURN675_RS00655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTURN675_RS00660	COG0772	Belongs to the SEDS family
BTURN675_RS00665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTURN675_RS00670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTURN675_RS00675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTURN675_RS00680	COG0849	cell division
BTURN675_RS00690	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BTURN675_RS00695	COG0653	protein targeting
BTURN675_RS00705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTURN675_RS00710	COG1049	propionate catabolic process, 2-methylcitrate cycle
BTURN675_RS00715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTURN675_RS00720	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTURN675_RS00725	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTURN675_RS00730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTURN675_RS00735	COG0316	Belongs to the HesB IscA family
BTURN675_RS00740	COG0504	CTP synthase activity
BTURN675_RS00745	COG0148	phosphopyruvate hydratase activity
BTURN675_RS00760	COG0175	sulfate reduction
BTURN675_RS00765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTURN675_RS00765	COG1648	precorrin-2 dehydrogenase activity
BTURN675_RS00775	COG2895	sulfate adenylyltransferase (ATP) activity
BTURN675_RS00785	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BTURN675_RS00790	COG4942	peptidase
BTURN675_RS00790	COG1388	LysM domain
BTURN675_RS00795	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BTURN675_RS00800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTURN675_RS00805	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BTURN675_RS00820	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTURN675_RS00835	COG0336	Belongs to the RNA methyltransferase TrmD family
BTURN675_RS00840	COG0335	large ribosomal subunit rRNA binding
BTURN675_RS00850	COG1605	Chorismate mutase
BTURN675_RS00850	COG0287	Prephenate dehydrogenase
BTURN675_RS00855	COG1605	Chorismate mutase
BTURN675_RS00855	COG0077	Prephenate dehydratase
BTURN675_RS00860	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTURN675_RS00865	COG0564	pseudouridine synthase activity
BTURN675_RS00870	COG0542	response to heat
BTURN675_RS00875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BTURN675_RS00880	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BTURN675_RS00880	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BTURN675_RS00910	COG0051	transcription antitermination factor activity, RNA binding
BTURN675_RS00915	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTURN675_RS00920	COG0088	Forms part of the polypeptide exit tunnel
BTURN675_RS00925	COG0089	rRNA binding
BTURN675_RS00930	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTURN675_RS00945	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTURN675_RS00950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTURN675_RS00960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTURN675_RS00965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTURN675_RS00970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTURN675_RS00980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTURN675_RS00985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTURN675_RS00990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BTURN675_RS01000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTURN675_RS01010	COG0201	protein transport
BTURN675_RS01015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTURN675_RS01025	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTURN675_RS01030	COG0202	RNA polymerase activity
BTURN675_RS01035	COG0203	ribosomal protein L17
BTURN675_RS01040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTURN675_RS01045	COG0242	peptide deformylase activity
BTURN675_RS01050	COG0009	L-threonylcarbamoyladenylate synthase
BTURN675_RS01055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTURN675_RS01065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTURN675_RS01070	COG0328	RNA-DNA hybrid ribonuclease activity
BTURN675_RS01075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTURN675_RS01080	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTURN675_RS01090	COG0450	alkyl hydroperoxide reductase
BTURN675_RS01100	COG1862	Preprotein translocase
BTURN675_RS01105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTURN675_RS01110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTURN675_RS01115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTURN675_RS01120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTURN675_RS01120	COG0301	tRNA thio-modification
BTURN675_RS01125	COG2814	Major facilitator Superfamily
BTURN675_RS01130	COG0109	protoheme IX farnesyltransferase activity
BTURN675_RS01135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTURN675_RS01140	COG1845	cytochrome c oxidase, subunit III
BTURN675_RS01145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTURN675_RS01150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTURN675_RS01155	COG0740	serine-type endopeptidase activity
BTURN675_RS01160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BTURN675_RS01165	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BTURN675_RS01170	COG1194	a g-specific adenine glycosylase
BTURN675_RS01175	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTURN675_RS01180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BTURN675_RS01185	COG1678	Uncharacterized ACR, COG1678
BTURN675_RS01190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTURN675_RS01195	COG0010	Belongs to the arginase family
BTURN675_RS01200	COG0126	phosphoglycerate kinase activity
BTURN675_RS01210	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BTURN675_RS01215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTURN675_RS01220	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BTURN675_RS01225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTURN675_RS01235	COG0354	folic acid binding
BTURN675_RS01245	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTURN675_RS01255	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTURN675_RS01260	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BTURN675_RS01270	COG0776	regulation of translation
BTURN675_RS01275	COG0312	modulator of DNA gyrase
BTURN675_RS01280	COG0312	modulator of DNA gyrase
BTURN675_RS01285	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BTURN675_RS01290	COG1792	Involved in formation and maintenance of cell shape
BTURN675_RS01295	COG1077	Cell shape determining protein MreB Mrl
BTURN675_RS01300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTURN675_RS01305	COG0511	ligase activity, forming carbon-carbon bonds
BTURN675_RS01310	COG0439	Biotin carboxylase
BTURN675_RS01315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTURN675_RS01320	COG0442	prolyl-tRNA aminoacylation
BTURN675_RS01325	COG0037	tRNA processing
BTURN675_RS01330	COG0825	malonyl-CoA metabolic process
BTURN675_RS01335	COG0587	DNA-directed DNA polymerase activity
BTURN675_RS01340	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTURN675_RS01345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTURN675_RS01350	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTURN675_RS01360	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BTURN675_RS01365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTURN675_RS01370	COG0750	zinc metalloprotease
BTURN675_RS01375	COG0575	Belongs to the CDS family
BTURN675_RS01380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTURN675_RS01390	COG0233	cytoplasmic translational termination
BTURN675_RS01395	COG0528	UMP kinase activity
BTURN675_RS01405	COG0052	Belongs to the universal ribosomal protein uS2 family
BTURN675_RS01415	COG2171	N-acyltransferase activity
BTURN675_RS01420	COG1074	ATP-dependent DNA helicase activity
BTURN675_RS01425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTURN675_RS01435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTURN675_RS01440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTURN675_RS01445	COG0563	adenylate kinase activity
BTURN675_RS01455	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTURN675_RS01460	COG0215	cysteine-tRNA ligase activity
BTURN675_RS01465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTURN675_RS01475	COG0697	spore germination
BTURN675_RS01485	COG0772	Belongs to the SEDS family
BTURN675_RS01490	COG0768	penicillin binding
BTURN675_RS01500	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BTURN675_RS01505	COG0495	leucyl-tRNA aminoacylation
BTURN675_RS01510	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BTURN675_RS01515	COG4535	Mg2 and Co2 transporter CorC
BTURN675_RS01520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTURN675_RS01540	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTURN675_RS01545	COG0363	glucosamine-6-phosphate deaminase activity
BTURN675_RS01550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTURN675_RS01555	COG0716	FMN binding
BTURN675_RS01565	COG0033	Phosphoglucomutase
BTURN675_RS01575	COG2009	succinate dehydrogenase
BTURN675_RS01580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BTURN675_RS01585	COG1053	succinate dehydrogenase
BTURN675_RS01590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTURN675_RS01595	COG0567	Dehydrogenase, E1 component
BTURN675_RS01600	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTURN675_RS01605	COG0045	succinate-CoA ligase (ADP-forming) activity
BTURN675_RS01610	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTURN675_RS01615	COG0811	peptide transport
BTURN675_RS01620	COG0848	biopolymer transport protein
BTURN675_RS01630	COG0823	Involved in the tonB-independent uptake of proteins
BTURN675_RS01635	COG2885	chlorophyll binding
BTURN675_RS01650	COG2706	6-phosphogluconolactonase activity
BTURN675_RS01655	COG0670	Belongs to the BI1 family
BTURN675_RS01660	COG0012	GTP binding
BTURN675_RS01670	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BTURN675_RS01680	COG0095	Lipoate-protein ligase
BTURN675_RS01685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTURN675_RS01685	COG0072	phenylalanine-tRNA ligase activity
BTURN675_RS01695	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTURN675_RS01700	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTURN675_RS01710	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTURN675_RS01725	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTURN675_RS01730	COG0316	Belongs to the HesB IscA family
BTURN675_RS01735	COG0719	Fe-S assembly protein
BTURN675_RS01740	COG0396	ATPase activity
BTURN675_RS01745	COG0719	Fe-S assembly protein
BTURN675_RS01750	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTURN675_RS01755	COG2166	iron-sulfur cluster assembly
BTURN675_RS01760	COG4238	major outer membrane lipoprotein
BTURN675_RS01770	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTURN675_RS01775	COG1846	Transcriptional regulator
BTURN675_RS01780	COG0259	pyridoxamine-phosphate oxidase activity
BTURN675_RS01785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTURN675_RS01790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTURN675_RS01795	COG0114	fumarate hydratase activity
BTURN675_RS01810	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTURN675_RS01820	COG1663	tetraacyldisaccharide 4'-kinase activity
BTURN675_RS01825	COG1132	(ABC) transporter
BTURN675_RS01830	COG0539	negative regulation of cytoplasmic translation
BTURN675_RS01835	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTURN675_RS01840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BTURN675_RS01845	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTURN675_RS01855	COG3107	peptidoglycan biosynthetic process
BTURN675_RS01855	COG1674	ftsk spoiiie
BTURN675_RS01860	COG0492	ferredoxin-NADP+ reductase activity
BTURN675_RS01865	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTURN675_RS01875	COG0537	adenosine 5'-monophosphoramidase activity
BTURN675_RS01880	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BTURN675_RS01885	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTURN675_RS01890	COG1136	(ABC) transporter
BTURN675_RS01895	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTURN675_RS01900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTURN675_RS01920	COG0084	hydrolase, TatD family'
BTURN675_RS01925	COG0470	DNA polymerase III
BTURN675_RS01930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTURN675_RS01935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTURN675_RS01940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTURN675_RS01955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTURN675_RS01970	COG0564	pseudouridine synthase activity
BTURN675_RS01975	COG1530	ribonuclease E activity
BTURN675_RS01980	COG1560	Kdo2-lipid A biosynthetic process
BTURN675_RS02000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTURN675_RS02020	COG3785	DNA binding
BTURN675_RS02030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTURN675_RS02035	COG0017	Asparaginyl-tRNA synthetase
BTURN675_RS02040	COG1448	Aminotransferase
BTURN675_RS02045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTURN675_RS02050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTURN675_RS02065	COG0512	Glutamine amidotransferase of anthranilate synthase
BTURN675_RS02065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTURN675_RS02070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTURN675_RS02080	COG0133	tryptophan synthase activity
BTURN675_RS02090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTURN675_RS02095	COG1435	thymidine kinase activity
BTURN675_RS02115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTURN675_RS02125	COG0616	signal peptide processing
BTURN675_RS02135	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BTURN675_RS02140	COG0850	regulation of cytokinetic process
BTURN675_RS02145	COG2894	cell division
BTURN675_RS02150	COG1214	PFAM Peptidase M22, glycoprotease
BTURN675_RS02155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTURN675_RS02160	COG1253	flavin adenine dinucleotide binding
BTURN675_RS02165	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTURN675_RS02165	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTURN675_RS02170	COG3715	PTS system
BTURN675_RS02175	COG3716	PTS system mannose fructose sorbose family IID component
BTURN675_RS02185	COG0501	Belongs to the peptidase M48B family
BTURN675_RS02190	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTURN675_RS02195	COG0469	pyruvate kinase activity
BTURN675_RS02200	COG0739	heme binding
BTURN675_RS02205	COG0217	transcriptional regulatory protein
BTURN675_RS02210	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTURN675_RS02215	COG0018	arginyl-trna synthetase
BTURN675_RS02225	COG2814	Major facilitator Superfamily
BTURN675_RS02245	COG0517	IMP dehydrogenase activity
BTURN675_RS02245	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BTURN675_RS02250	COG2926	Belongs to the UPF0265 family
BTURN675_RS02255	COG2925	Exonuclease
BTURN675_RS02260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BTURN675_RS02265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTURN675_RS02270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTURN675_RS02280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BTURN675_RS02285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BTURN675_RS02290	COG0107	imidazoleglycerol-phosphate synthase activity
BTURN675_RS02295	COG0140	phosphoribosyl-ATP diphosphatase activity
BTURN675_RS02295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BTURN675_RS02300	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BTURN675_RS02305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTURN675_RS02310	COG0302	gtp cyclohydrolase
BTURN675_RS02315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BTURN675_RS02320	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTURN675_RS02335	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTURN675_RS02340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTURN675_RS02345	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTURN675_RS02355	COG1007	ATP synthesis coupled electron transport
BTURN675_RS02360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTURN675_RS02365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTURN675_RS02370	COG0713	ATP synthesis coupled electron transport
BTURN675_RS02375	COG0839	Belongs to the complex I subunit 6 family
BTURN675_RS02380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTURN675_RS02385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTURN675_RS02400	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTURN675_RS02405	COG0649	NAD binding
BTURN675_RS02405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTURN675_RS02410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTURN675_RS02415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTURN675_RS02425	COG0285	dihydrofolate synthase activity
BTURN675_RS02430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTURN675_RS02445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTURN675_RS02455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTURN675_RS02465	COG1914	H( )-stimulated, divalent metal cation uptake system
BTURN675_RS02470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTURN675_RS02480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTURN675_RS02495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTURN675_RS02500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTURN675_RS02505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTURN675_RS02510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTURN675_RS02520	COG4208	sulfate ABC transporter
BTURN675_RS02525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BTURN675_RS02530	COG4150	thiosulfate binding
BTURN675_RS02540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTURN675_RS02545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTURN675_RS02555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTURN675_RS02565	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BTURN675_RS02570	COG0830	nickel cation binding
BTURN675_RS02575	COG0804	urea catabolic process
BTURN675_RS02580	COG0832	Belongs to the urease beta subunit family
BTURN675_RS02585	COG0831	urea catabolic process
BTURN675_RS02590	COG0829	nickel cation binding
BTURN675_RS02595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTURN675_RS02595	COG0519	Catalyzes the synthesis of GMP from XMP
BTURN675_RS02600	COG0517	IMP dehydrogenase activity
BTURN675_RS02600	COG0516	GMP reductase activity
BTURN675_RS02605	COG0579	oxidoreductase
BTURN675_RS02610	COG1160	GTP binding
BTURN675_RS02615	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTURN675_RS02620	COG0124	histidyl-tRNA synthetase
BTURN675_RS02635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTURN675_RS02640	COG0105	UTP biosynthetic process
BTURN675_RS02650	COG0483	inositol monophosphate 1-phosphatase activity
BTURN675_RS02655	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BTURN675_RS02665	COG0736	holo-[acyl-carrier-protein] synthase activity
BTURN675_RS02670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BTURN675_RS02675	COG0571	ribonuclease III activity
BTURN675_RS02680	COG0681	Belongs to the peptidase S26 family
BTURN675_RS02685	COG0481	GTPase activity
BTURN675_RS02690	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BTURN675_RS02695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTURN675_RS02700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTURN675_RS02705	COG2867	negative regulation of translational initiation
BTURN675_RS02710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BTURN675_RS02720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTURN675_RS02725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTURN675_RS02760	COG0085	RNA polymerase activity
BTURN675_RS02770	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTURN675_RS02775	COG0081	regulation of translation
BTURN675_RS02780	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTURN675_RS02785	COG0250	Participates in transcription elongation, termination and antitermination
BTURN675_RS02795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTURN675_RS02800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTURN675_RS02805	COG0049	tRNA binding
BTURN675_RS02810	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTURN675_RS02825	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTURN675_RS02830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTURN675_RS02840	COG0316	Belongs to the HesB IscA family
BTURN675_RS02840	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTURN675_RS02850	COG2095	MarC family integral membrane protein
BTURN675_RS02855	COG0561	phosphatase activity
BTURN675_RS02860	COG0598	Magnesium transport protein CorA
BTURN675_RS02865	COG1011	Hydrolase
BTURN675_RS02875	COG0181	hydroxymethylbilane synthase activity
BTURN675_RS02880	COG1587	Uroporphyrinogen-III synthase
BTURN675_RS02910	COG3118	belongs to the thioredoxin family
BTURN675_RS02925	COG0129	dihydroxy-acid dehydratase activity
BTURN675_RS02930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTURN675_RS02935	COG3978	acetolactate synthase activity
BTURN675_RS02960	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTURN675_RS02965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTURN675_RS02970	COG0626	cystathionine gamma-synthase activity
BTURN675_RS02975	COG0254	rRNA binding
BTURN675_RS02980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTURN675_RS02990	COG0149	triose-phosphate isomerase activity
BTURN675_RS02995	COG0205	6-phosphofructokinase activity
BTURN675_RS03000	COG1045	serine acetyltransferase
BTURN675_RS03005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTURN675_RS03010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTURN675_RS03015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTURN675_RS03020	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTURN675_RS03025	COG0859	PFAM glycosyl transferase family 9
BTURN675_RS03030	COG0859	PFAM glycosyl transferase family 9
BTURN675_RS03035	COG0438	transferase activity, transferring glycosyl groups
BTURN675_RS03040	COG1519	Transferase
BTURN675_RS03050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTURN675_RS03065	COG1561	YicC-like family, N-terminal region
BTURN675_RS03070	COG1846	Transcriptional regulator
BTURN675_RS03075	COG0194	GDP metabolic process
BTURN675_RS03085	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BTURN675_RS03090	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTURN675_RS03090	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTURN675_RS03100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTURN675_RS03105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTURN675_RS03115	COG1322	Protein conserved in bacteria
BTURN675_RS03125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BTURN675_RS03135	COG0552	protein localization to endoplasmic reticulum
BTURN675_RS03150	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BTURN675_RS03165	COG1074	ATP-dependent DNA helicase activity
BTURN675_RS03175	COG0596	Alpha beta hydrolase