locus-tag	class	description
GT348_RS00020	ENOG4105CKK	Glycosyl transferase, family 2
GT348_RS00025	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GT348_RS00030	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GT348_RS00040	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GT348_RS00090	ENOG4105II7	pyrroline-5-carboxylate reductase
GT348_RS00105	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
GT348_RS00120	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
GT348_RS00125	ENOG4105C3G	gtp-binding protein
GT348_RS00130	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
GT348_RS00140	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GT348_RS00155	ENOG4105C5X	domain protein
GT348_RS00165	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
GT348_RS00235	ENOG4105UFH	BadM Rrf2 family transcriptional regulator
GT348_RS00240	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
GT348_RS00270	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
GT348_RS00280	ENOG4105C8Y	Acetylornithine aminotransferase
GT348_RS00300	ENOG4105DTN	riboflavin biosynthesis protein ribF
GT348_RS00310	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
GT348_RS00320	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
GT348_RS00325	ENOG4105CXG	d-lactate dehydrogenase
GT348_RS00350	ENOG4108KK1	membrane protein AbrB duplication
GT348_RS00365	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
GT348_RS00375	ENOG4105D2N	Aldolase
GT348_RS00385	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
GT348_RS00405	ENOG41090R7	Ferric uptake
GT348_RS00415	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
GT348_RS00420	ENOG4108WRK	Transcriptional regulator
GT348_RS00445	ENOG4105F0N	pyrophosphate phospho-hydrolase
GT348_RS00465	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
GT348_RS00475	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
GT348_RS00480	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
GT348_RS00485	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
GT348_RS00490	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GT348_RS00495	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GT348_RS00500	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
GT348_RS00505	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GT348_RS00510	ENOG4105C1J	atp-dependent rna helicase
GT348_RS00515	ENOG4105EMU	Dehydrogenase
GT348_RS00520	ENOG4108UJU	UPF0301 protein
GT348_RS00570	ENOG4105CPN	adenine deaminase
GT348_RS00575	ENOG4105DQ4	alcohol dehydrogenase
GT348_RS00580	ENOG4108ZHJ	Organic hydroperoxide resistance protein
GT348_RS00585	ENOG4105DQ4	alcohol dehydrogenase
GT348_RS00590	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
GT348_RS00595	ENOG4105DJ9	glucan biosynthesis protein
GT348_RS00605	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
GT348_RS00615	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GT348_RS00660	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
GT348_RS00670	ENOG4105K64	Glycosyl transferase, family 2
GT348_RS00690	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
GT348_RS00705	ENOG4105E2Z	phosphate ABC transporter (Permease
GT348_RS00710	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
GT348_RS00720	ENOG4105C85	amino acid
GT348_RS00725	ENOG4105E4C	Lytic transglycosylase catalytic
GT348_RS00730	ENOG41060BG	Tetr family transcriptional regulator
GT348_RS00735	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
GT348_RS00745	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GT348_RS00770	ENOG4105DJV	ribulose-phosphate 3-epimerase
GT348_RS00780	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
GT348_RS00785	ENOG4105DHZ	alpha beta
GT348_RS00800	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
GT348_RS00810	ENOG4105C26	Dehydrogenase
GT348_RS00815	ENOG4105C5Q	Transcriptional regulator
GT348_RS00820	ENOG4105D3R	alkyl hydroperoxide reductase
GT348_RS00825	ENOG4108JU3	Alkyl hydroperoxide reductase
GT348_RS00840	ENOG4105F1S	paraquat-inducible protein a
GT348_RS00845	ENOG4105DY2	Paraquat-inducible protein b
GT348_RS00865	ENOG410683Z	Preprotein translocase SecE subunit
GT348_RS00880	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GT348_RS00885	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
GT348_RS00890	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
GT348_RS00895	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
GT348_RS00900	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
GT348_RS00965	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
GT348_RS00970	ENOG4105DZ1	carboxypeptidase
GT348_RS00990	ENOG4107QMP	dna polymerase iii subunits gamma and tau
GT348_RS00995	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
GT348_RS01000	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
GT348_RS01005	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
GT348_RS01020	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
GT348_RS01025	ENOG4105CAT	Cytidine monophosphate kinase
GT348_RS01030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
GT348_RS01040	ENOG4105K64	Glycosyl transferase, family 2
GT348_RS01060	ENOG4107R51	Glycosyl transferase, family 2
GT348_RS01070	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
GT348_RS01075	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
GT348_RS01085	ENOG4105SYT	Methylenetetrahydrofolate reductase
GT348_RS01095	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
GT348_RS01100	ENOG4105C22	threonyL-tRNA synthetase
GT348_RS01115	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
GT348_RS01120	ENOG4105EB3	Histidine kinase
GT348_RS01130	ENOG4107QNK	)-transporter
GT348_RS01145	ENOG4105EGS	Mechanosensitive ion channel
GT348_RS01175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
GT348_RS01180	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
GT348_RS01185	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
GT348_RS01205	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
GT348_RS01210	ENOG4108UJD	30S ribosomal protein S9
GT348_RS01215	ENOG4105CM2	brancheD-chain amino acid aminotransferase
GT348_RS01240	ENOG4108ZZ3	UPF0260 protein
GT348_RS01265	ENOG4105Y49	secretion protein, HlyD family
GT348_RS01290	ENOG4105DUX	Transporter
GT348_RS01295	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
GT348_RS01300	ENOG4105CI3	gtp-binding protein typa
GT348_RS01315	ENOG4105K8N	protein family UPF0079, ATPase
GT348_RS01330	ENOG4105K63	Thioredoxin
GT348_RS01355	ENOG410901P	UPF0249 protein
GT348_RS01375	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
GT348_RS01385	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GT348_RS01395	ENOG4105KUZ	arsenate reductase
GT348_RS01400	ENOG4105C85	amino acid
GT348_RS01420	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
GT348_RS01425	ENOG4105BZA	Phosphoglycerate kinase
GT348_RS01430	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
GT348_RS01445	ENOG4105YVS	arsR family transcriptional regulator
GT348_RS01450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GT348_RS01455	ENOG4105C2N	RNA methyltransferase TrmH family group 3
GT348_RS01480	ENOG4107UZV	polysaccharide biosynthesis
GT348_RS01495	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
GT348_RS01505	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
GT348_RS01510	ENOG4108TJN	glycosyl transferase group 1
GT348_RS01520	ENOG41084CK	capsule polysaccharide
GT348_RS01525	ENOG4105E12	capsule polysaccharide
GT348_RS01540	ENOG41080TC	multidrug resistance protein
GT348_RS01550	ENOG4105CV8	reductase
GT348_RS01585	ENOG4105CN1	protease
GT348_RS01600	ENOG4105C79	DNA protecting protein DprA
GT348_RS01605	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
GT348_RS01610	ENOG4105CD3	dihydroorotase
GT348_RS01615	ENOG4105CXT	aspartate transcarbamylase
GT348_RS01620	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GT348_RS01630	ENOG4105CSM	endonuclease III
GT348_RS01635	ENOG4105BZ1	(ABC) transporter
GT348_RS01645	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
GT348_RS01650	ENOG4107U9T	Pfam:Ribonuclease_BN
GT348_RS01655	ENOG4105K6T	rare lipoprotein A
GT348_RS01660	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
GT348_RS01670	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
GT348_RS01675	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
GT348_RS01690	ENOG4105E5Q	amino acid AbC transporter
GT348_RS01710	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
GT348_RS01720	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
GT348_RS01735	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
GT348_RS01740	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
GT348_RS01745	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
GT348_RS01750	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
GT348_RS01755	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
GT348_RS01770	ENOG4105CSA	Coproporphyrinogen iii oxidase
GT348_RS01775	ENOG4105DFH	Transport of potassium into the cell (By similarity)
GT348_RS01780	ENOG4105DFA	alanine racemase domain protein
GT348_RS01785	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GT348_RS01810	ENOG4108FN7	Aldo keto reductase
GT348_RS01835	ENOG4105DTT	CRISPR-associated helicase, cas3
GT348_RS01850	ENOG41060M0	Crispr-associated protein, cse4 family
GT348_RS01855	ENOG4108VWQ	crispr-associated protein
GT348_RS01870	ENOG4105PWE	CRISPR-associated protein cas2
GT348_RS01895	ENOG4108R85	Short chain dehydrogenase
GT348_RS01905	ENOG4105CMT	Dihydroxyacetone kinase
GT348_RS01910	ENOG4108YZG	isomerase
GT348_RS01915	ENOG4105DKT	Transcriptional regulator
GT348_RS01930	ENOG4105CKI	cobalamin synthesis protein
GT348_RS01970	ENOG4105DZ0	fad dependent oxidoreductase
GT348_RS01980	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GT348_RS02000	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
GT348_RS02010	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
GT348_RS02015	ENOG4107QNK	)-transporter
GT348_RS02020	ENOG4105C9Q	fumarate hydratase class II
GT348_RS02025	ENOG4107R1I	NAD-dependent malic enzyme
GT348_RS02035	ENOG4105KWW	Biogenesis protein
GT348_RS02040	ENOG4107QX9	Thiol disulfide interChange protein
GT348_RS02050	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
GT348_RS02055	ENOG41060IM	Heme exporter protein
GT348_RS02075	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
GT348_RS02085	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GT348_RS02095	ENOG4105D1H	recombination factor protein RarA
GT348_RS02120	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
GT348_RS02125	ENOG4105NWN	ApaG protein
GT348_RS02155	ENOG4105CEP	NADH dehydrogenase
GT348_RS02165	ENOG4107TF3	peptidylprolyl cis-trans isomerase
GT348_RS02170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
GT348_RS02175	ENOG4105CDY	transcriptional regulatory protein
GT348_RS02180	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
GT348_RS02185	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
GT348_RS02195	ENOG4107YD3	Thioesterase
GT348_RS02200	ENOG4105E02	MotA TolQ exbB proton channel
GT348_RS02205	ENOG4108ZZF	transport protein (ExbD)
GT348_RS02220	ENOG4105KCK	Peptidoglycan-associated lipoprotein
GT348_RS02230	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
GT348_RS02240	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
GT348_RS02245	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
GT348_RS02260	ENOG4105C88	aminopeptidase
GT348_RS02270	ENOG4105CIH	Imidazole acetol-phosphate transaminase
GT348_RS02285	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
GT348_RS02290	ENOG4108J5G	6-phosphogluconate dehydrogenase
GT348_RS02295	ENOG410667J	hydrolase
GT348_RS02300	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
GT348_RS02305	ENOG4105E66	phosphoriboisomerase A
GT348_RS02310	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
GT348_RS02325	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
GT348_RS02330	ENOG4105DFI	Membrane
GT348_RS02335	ENOG4105DCT	glycerol dehydrogenase
GT348_RS02340	ENOG4107VXZ	Hydrolase
GT348_RS02355	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
GT348_RS02360	ENOG4105CIF	Ornithine Cyclodeaminase
GT348_RS02405	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GT348_RS02415	ENOG4105C03	ribonuclease
GT348_RS02420	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
GT348_RS02425	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
GT348_RS02430	ENOG4107TSN	permease
GT348_RS02450	ENOG4105CJN	penicillin-binding protein
GT348_RS02455	ENOG4105CNI	cell division protein FtsW
GT348_RS02465	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
GT348_RS02470	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
GT348_RS02485	ENOG4105C9M	aspartyl-trna synthetase
GT348_RS02495	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
GT348_RS02500	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
GT348_RS02505	ENOG4105C75	arginyL-tRNA synthetase
GT348_RS02520	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
GT348_RS02530	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
GT348_RS02535	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
GT348_RS02550	ENOG4105DP0	ferredoxin-NADP reductase
GT348_RS02555	ENOG4105DC8	reductase
GT348_RS02560	ENOG4105DSW	Fusaric acid resistance protein
GT348_RS02580	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
GT348_RS02595	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
GT348_RS02605	ENOG4105C8N	cysteinyl-tRNA synthetase
GT348_RS02610	ENOG4107QI1	Mate efflux family protein
GT348_RS02615	ENOG4105F27	Major Facilitator
GT348_RS02620	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
GT348_RS02625	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
GT348_RS02635	ENOG4107B2H	carbonic anhydrase
GT348_RS02640	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
GT348_RS02660	ENOG4105D49	3-dehydroquinate synthase
GT348_RS02675	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
GT348_RS02680	ENOG4105CEV	competence damage-inducible protein
GT348_RS02690	ENOG4105M6F	mutator MutT protein
GT348_RS02705	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
GT348_RS02720	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
GT348_RS02730	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
GT348_RS02735	ENOG4105C3F	Signal peptidase i
GT348_RS02740	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
GT348_RS02745	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
GT348_RS02750	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
GT348_RS02755	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
GT348_RS02760	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
GT348_RS02765	ENOG4105KNE	Phosphatidate cytidylyltransferase
GT348_RS02780	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT348_RS02790	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
GT348_RS02795	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
GT348_RS02805	ENOG4105GYT	Protein of unknown function (DUF1009)
GT348_RS02810	ENOG4108UYE	Lactoylglutathione lyase
GT348_RS02820	ENOG4105VG0	50S ribosomal protein l34
GT348_RS02825	ENOG41087PG	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
GT348_RS02830	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
GT348_RS02835	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GT348_RS02840	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
GT348_RS02855	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
GT348_RS02860	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
GT348_RS02865	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
GT348_RS02870	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
GT348_RS02875	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
GT348_RS02880	ENOG4108ZNX	Heat shock protein
GT348_RS02890	ENOG4108IUZ	ABC transporter
GT348_RS02905	ENOG4105C2X	Arabinose 5-phosphate isomerase
GT348_RS02945	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
GT348_RS02955	ENOG4108RRZ	Transcription elongation factor GreB
GT348_RS02960	ENOG4105D7Z	glutathione synthase
GT348_RS02965	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
GT348_RS02975	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
GT348_RS02990	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
GT348_RS03010	ENOG4105RQ9	TPR repeat-containing protein
GT348_RS03035	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
GT348_RS03040	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
GT348_RS03050	ENOG4108V06	Glutathione peroxidase
GT348_RS03055	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
GT348_RS03060	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GT348_RS03065	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
GT348_RS03075	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
GT348_RS03085	ENOG4105CA3	membrane-bound lytic murein transglycosylase
GT348_RS03110	ENOG4108HWH	(ABC) transporter
GT348_RS03115	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
GT348_RS03120	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
GT348_RS03125	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
GT348_RS03130	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
GT348_RS03135	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
GT348_RS03160	ENOG4105HFZ	Membrane
GT348_RS03175	ENOG4105CCU	oxidase (Subunit III)
GT348_RS03180	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
GT348_RS03200	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GT348_RS03210	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
GT348_RS03220	ENOG4105C02	permease
GT348_RS03225	ENOG4105C5H	ABC transporter
GT348_RS03230	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
GT348_RS03235	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
GT348_RS03240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
GT348_RS03245	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GT348_RS03250	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
GT348_RS03290	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
GT348_RS03305	ENOG4105CA9	Pyruvate kinase
GT348_RS03325	ENOG4107R8N	Glycosyl transferase, family 2
GT348_RS03330	ENOG4105FBD	synthase
GT348_RS03335	ENOG4105FE1	phytoene synthase
GT348_RS03340	ENOG4107S11	squalene-associated FAD-dependent desaturase
GT348_RS03350	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
GT348_RS03355	ENOG4105CE9	30S ribosomal protein S2
GT348_RS03360	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
GT348_RS03365	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
GT348_RS03375	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GT348_RS03390	ENOG4105C28	cystathionine
GT348_RS03395	ENOG4105CHM	Aminotransferase
GT348_RS03400	ENOG4105C0P	Mg chelatase subunit ChlI
GT348_RS03405	ENOG4108JQ1	Dehydrogenase
GT348_RS03415	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
GT348_RS03420	ENOG4105CQC	Prephenate dehydratase
GT348_RS03425	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
GT348_RS03430	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
GT348_RS03435	ENOG4105VEQ	Cold shock protein
GT348_RS03440	ENOG4105CB5	ATP-dependent DNA helicase recG
GT348_RS03455	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
GT348_RS03460	ENOG4105KPV	Transcriptional regulator
GT348_RS03485	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
GT348_RS03495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
GT348_RS03500	ENOG4105CGK	Exodeoxyribonuclease III
GT348_RS03510	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
GT348_RS03525	ENOG4105W0E	50S ribosomal protein L33
GT348_RS03535	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
GT348_RS03560	ENOG4105CP7	Triose-phosphate isomerase
GT348_RS03570	ENOG4105CRQ	synthase (Component I)
GT348_RS03575	ENOG4107QYG	anthranilate phosphoribosyltransferase
GT348_RS03580	ENOG4105DK0	Indole-3-glycerol phosphate synthase
GT348_RS03585	ENOG4108JYK	Dehydrogenase
GT348_RS03590	ENOG4105CPP	Dehydrogenase, E1 component
GT348_RS03605	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
GT348_RS03610	ENOG4108Z1B	Cyclase dehydrase
GT348_RS03645	ENOG4105C28	cystathionine
GT348_RS03660	ENOG4107SC1	transglycosylase
GT348_RS03665	ENOG4108ZCF	integral membrane protein
GT348_RS03670	ENOG4105C83	adenylosuccinate lyase
GT348_RS03675	ENOG4107QPR	SAICAR synthetase
GT348_RS03680	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
GT348_RS03690	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
GT348_RS03695	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
GT348_RS03715	ENOG41082FP	UPF0102 protein
GT348_RS03720	ENOG4105D52	delta-aminolevulinic acid dehydratase
GT348_RS03725	ENOG4105CUB	amino acid
GT348_RS03730	ENOG4105CUB	amino acid
GT348_RS03735	ENOG4105CUB	amino acid
GT348_RS03740	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
GT348_RS03745	ENOG4105C1J	atp-dependent rna helicase
GT348_RS03805	ENOG4108IU3	tonb-dependent siderophore receptor
GT348_RS03830	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
GT348_RS03835	ENOG4105IE8	Alpha-ketoglutarate permease
GT348_RS03845	ENOG4105C4M	(Ubiquinol oxidase) subunit I
GT348_RS03850	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
GT348_RS03890	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
GT348_RS03910	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
GT348_RS03915	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
GT348_RS03930	ENOG4105DC7	peptidase M24
GT348_RS03935	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
GT348_RS03945	ENOG4105W5Q	DNA repair protein (RadC
GT348_RS03950	ENOG4105W5Q	DNA repair protein (RadC
GT348_RS03955	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
GT348_RS03975	ENOG41082FS	50S ribosomal protein L31
GT348_RS03980	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
GT348_RS03995	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
GT348_RS04005	ENOG4105C5H	ABC transporter
GT348_RS04010	ENOG4108JJ9	ABC, transporter
GT348_RS04015	ENOG4108JJ8	(ABC) transporter
GT348_RS04025	ENOG4105C9U	ATP-dependent DNA helicase RecQ
GT348_RS04035	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
GT348_RS04040	ENOG4107XZX	Involved in the transcription termination process (By similarity)
GT348_RS04045	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
GT348_RS04070	ENOG4105CMG	Carbohydrate kinase
GT348_RS04085	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
GT348_RS04090	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GT348_RS04095	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
GT348_RS04100	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
GT348_RS04125	ENOG4105CMR	udp-glucose 4-epimerase
GT348_RS04140	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
GT348_RS04145	ENOG4105C01	Dihydroxy-acid dehydratase
GT348_RS04150	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
GT348_RS04165	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
GT348_RS04170	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
GT348_RS04175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
GT348_RS04180	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
GT348_RS04185	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
GT348_RS04190	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
GT348_RS04195	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
GT348_RS04200	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
GT348_RS04220	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
GT348_RS04240	ENOG4105EU0	Major facilitator Superfamily
GT348_RS04260	ENOG4105DUX	Transporter
GT348_RS04265	ENOG4108UQY	Iron-storage protein
GT348_RS04275	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
GT348_RS04280	ENOG4107RCI	amp-dependent synthetase and ligase
GT348_RS04290	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
GT348_RS04350	ENOG4105HHA	aminodeoxychorismate lyase
GT348_RS04355	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
GT348_RS04360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
GT348_RS04370	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
GT348_RS04380	ENOG4105C9K	Endothelin-converting enzyme 1
GT348_RS04390	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
GT348_RS04405	ENOG4105CIG	ABC transporter
GT348_RS04425	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
GT348_RS04430	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
GT348_RS04435	ENOG4105C4W	S-formylglutathione hydrolase
GT348_RS04440	ENOG4107QPD	alcohol dehydrogenase
GT348_RS04445	ENOG4105FFC	UPF0187 protein
GT348_RS04450	ENOG4108VJ1	Transcriptional regulator (CarD family
GT348_RS04470	ENOG4105CFU	surface antigen
GT348_RS04480	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
GT348_RS04490	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
GT348_RS04495	ENOG4107RCQ	(CBS) domain
GT348_RS04505	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
GT348_RS04545	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
GT348_RS04555	ENOG4105EAH	synthase
GT348_RS04560	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
GT348_RS04570	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
GT348_RS04575	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
GT348_RS04580	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
GT348_RS04620	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
GT348_RS04630	ENOG4105D1K	glutamate--cysteine ligase
GT348_RS04645	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GT348_RS04655	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
GT348_RS04685	ENOG4107RZZ	dna polymerase iii epsilon subunit
GT348_RS04690	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
GT348_RS04695	ENOG4105E2X	shikimate dehydrogenase
GT348_RS04705	ENOG4105CH7	arginosuccinase
GT348_RS04715	ENOG4107YM4	Beta-lactamase domain-containing protein
GT348_RS04720	ENOG4105F8V	Hydrolase, tatD family
GT348_RS04725	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
GT348_RS04735	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
GT348_RS04740	ENOG4105DZ1	carboxypeptidase
GT348_RS04745	ENOG4105CVE	Lytic murein transglycosylase
GT348_RS04760	ENOG4107PE3	Mammalian cell entry related domain protein
GT348_RS04765	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
GT348_RS04770	ENOG4105CUB	amino acid
GT348_RS04785	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
GT348_RS04795	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
GT348_RS04800	ENOG4105CUT	histidyl-tRNA synthetase
GT348_RS04805	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
GT348_RS04820	ENOG4105CFH	Aspartokinase
GT348_RS04825	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
GT348_RS04830	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
GT348_RS04840	ENOG4105VW4	glutaredoxin 3
GT348_RS04845	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GT348_RS04865	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
GT348_RS04880	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GT348_RS04900	ENOG4105C0B	DNA polymerase III (alpha subunit)
GT348_RS04905	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
GT348_RS04910	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
GT348_RS04920	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
GT348_RS04935	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
GT348_RS04945	ENOG4105K70	DNA-binding protein
GT348_RS04950	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
GT348_RS04960	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GT348_RS04965	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
GT348_RS04975	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
GT348_RS04985	ENOG4105C1J	atp-dependent rna helicase
GT348_RS04990	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
GT348_RS05000	ENOG4105VG1	fes assembly suf system protein
GT348_RS05010	ENOG4105JRK	feS assembly protein SufD
GT348_RS05015	ENOG4105C3K	feS assembly ATPase SufC
GT348_RS05030	ENOG4106BRA	Membrane
GT348_RS05050	ENOG4107R4J	Chloride channel
GT348_RS05055	ENOG4107R4J	Chloride channel
GT348_RS05060	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
GT348_RS05065	ENOG4105KDC	50s ribosomal protein l28
GT348_RS05070	ENOG4108JJ7	ABC transporter
GT348_RS05080	ENOG4105F4G	Membrane
GT348_RS05095	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GT348_RS05100	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
GT348_RS05110	ENOG41082R8	50S ribosomal protein l32
GT348_RS05125	ENOG41090HR	transcriptional regulator
GT348_RS05130	ENOG4105K5G	30S ribosomal protein S21
GT348_RS05150	ENOG4105ETT	transcriptional Regulator, LysR family
GT348_RS05155	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
GT348_RS05165	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
GT348_RS05170	ENOG4105DSW	Fusaric acid resistance protein
GT348_RS05185	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
GT348_RS05190	ENOG4105K46	50S ribosomal protein l27
GT348_RS05195	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GT348_RS05205	ENOG4107QR9	Iron-sulfur cluster binding protein
GT348_RS05215	ENOG4105C7K	acetolactate synthase
GT348_RS05235	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
GT348_RS05250	ENOG4107YUR	Cell division protein mraZ
GT348_RS05255	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
GT348_RS05265	ENOG4105CJN	penicillin-binding protein
GT348_RS05280	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
GT348_RS05285	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
GT348_RS05300	ENOG4105DFU	Cell wall formation (By similarity)
GT348_RS05305	ENOG4105D4A	Cell wall formation (By similarity)
GT348_RS05310	ENOG4105CPF	Cell wall formation (By similarity)
GT348_RS05315	ENOG4108UFP	Essential cell division protein (By similarity)
GT348_RS05320	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
GT348_RS05325	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
GT348_RS05335	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GT348_RS05340	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
GT348_RS05345	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
GT348_RS05350	ENOG4105C37	(CBS) domain
GT348_RS05355	ENOG4108RWI	nicotinamidase
GT348_RS05405	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GT348_RS05410	ENOG4105CUV	Homoserine Kinase
GT348_RS05415	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
GT348_RS05465	ENOG4105CHM	Aminotransferase
GT348_RS05470	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
GT348_RS05475	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GT348_RS05480	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
GT348_RS05485	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
GT348_RS05490	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
GT348_RS05500	ENOG4105K5M	30s ribosomal protein S16
GT348_RS05520	ENOG4105C1J	atp-dependent rna helicase
GT348_RS05525	ENOG4105DWV	Homoserine O-trans-acetylase
GT348_RS05530	ENOG4105DWV	Homoserine O-trans-acetylase
GT348_RS05540	ENOG4108RCM	Nitroreductase
GT348_RS05575	ENOG4105D48	metallophosphoesterase
GT348_RS05580	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
GT348_RS05620	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
GT348_RS05625	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
GT348_RS05630	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
GT348_RS05635	ENOG4105ECY	inositol monophosphatase
GT348_RS05650	ENOG4106VK6	Flagellar motor protein
GT348_RS05655	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
GT348_RS05665	ENOG4105C7N	Xanthine uracil vitamin C permease
GT348_RS05670	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
GT348_RS05675	ENOG4105CTB	Polyprenyl synthetase
GT348_RS05680	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
GT348_RS05685	ENOG4105DX0	Hemolysin A
GT348_RS05690	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GT348_RS05695	ENOG4105CDH	Citrulline--aspartate ligase
GT348_RS05700	ENOG4108V1T	peptidylprolyl cis-trans isomerase
GT348_RS05705	ENOG4105C31	Tryptophanyl-tRNA synthetase
GT348_RS05715	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
GT348_RS05720	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
GT348_RS05725	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
GT348_RS05730	ENOG41082BR	50S ribosomal protein L35
GT348_RS05735	ENOG4105DZG	Dehydrogenase
GT348_RS05745	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
GT348_RS05750	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
GT348_RS05755	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
GT348_RS05765	ENOG4105BZU	Histidine kinase
GT348_RS05775	ENOG4107R39	(ABC) transporter
GT348_RS05790	ENOG4105E9Q	Acyl-transferase
GT348_RS05815	ENOG4108IYU	L-aspartate oxidase
GT348_RS05825	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
GT348_RS05830	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
GT348_RS05835	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
GT348_RS05840	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
GT348_RS05875	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
GT348_RS05880	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
GT348_RS05885	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
GT348_RS05915	ENOG4107SZR	mannose-6-phosphate isomerase
GT348_RS05920	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
GT348_RS05955	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
GT348_RS05960	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
GT348_RS05965	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
GT348_RS05970	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
GT348_RS05975	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
GT348_RS05980	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
GT348_RS05995	ENOG4105DXC	membrane
GT348_RS06005	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
GT348_RS06010	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
GT348_RS06015	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
GT348_RS06020	ENOG4105C7B	Threonine dehydratase
GT348_RS06025	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
GT348_RS06030	ENOG4105W8H	transhydrogenase (subunit alpha
GT348_RS06040	ENOG4105C26	Dehydrogenase
GT348_RS06045	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
GT348_RS06055	ENOG4105E0X	reductase
GT348_RS06070	ENOG4105CN1	protease
GT348_RS06075	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
GT348_RS06080	ENOG4105BZ1	(ABC) transporter
GT348_RS06085	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GT348_RS06125	ENOG4105CEC	DNA methylase N-4 N-6
GT348_RS06130	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
GT348_RS06155	ENOG4105BZS	acriflavin resistance protein
GT348_RS06160	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GT348_RS06170	ENOG4108ZT0	50S ribosomal protein l17
GT348_RS06175	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GT348_RS06180	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
GT348_RS06185	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GT348_RS06190	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
GT348_RS06200	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
GT348_RS06205	ENOG4105VPB	50S ribosomal protein L30
GT348_RS06210	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
GT348_RS06215	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
GT348_RS06220	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
GT348_RS06225	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
GT348_RS06230	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
GT348_RS06235	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GT348_RS06240	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
GT348_RS06245	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
GT348_RS06250	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
GT348_RS06260	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
GT348_RS06265	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
GT348_RS06270	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
GT348_RS06275	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
GT348_RS06280	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GT348_RS06285	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
GT348_RS06290	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
GT348_RS06295	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
GT348_RS06300	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
GT348_RS06305	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
GT348_RS06310	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
GT348_RS06315	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
GT348_RS06320	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
GT348_RS06330	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
GT348_RS06335	ENOG4108VZM	50s ribosomal protein L10
GT348_RS06340	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
GT348_RS06345	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
GT348_RS06350	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GT348_RS06365	ENOG41062D9	Histidine kinase
GT348_RS06375	ENOG4107QSV	RmuC domain protein
GT348_RS06390	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
GT348_RS06400	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
GT348_RS06405	ENOG4107E2E	PKHD-type hydroxylase
GT348_RS06420	ENOG4105C8T	Leucyl-tRNA synthetase
GT348_RS06430	ENOG4105KJF	protein tyrosine phosphatase
GT348_RS06435	ENOG4105C5I	Dehydrogenase
GT348_RS06440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
GT348_RS06450	ENOG4105DC1	bifunctional purine biosynthesis protein purh
GT348_RS06455	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GT348_RS06480	ENOG4107SC1	transglycosylase
GT348_RS06500	ENOG4105KK4	UPF0060 membrane protein
GT348_RS06505	ENOG4105BZU	Histidine kinase
GT348_RS06510	ENOG4108YZA	Nitrogen regulatory protein pii
GT348_RS06520	ENOG4105D7W	serine acetyltransferase
GT348_RS06525	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
GT348_RS06540	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
GT348_RS06545	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
GT348_RS06555	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
GT348_RS06565	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
GT348_RS06590	ENOG4108Z0Z	intracellular protease Pfpi family
GT348_RS06610	ENOG4108IG5	Transcriptional regulator
GT348_RS06615	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
GT348_RS06625	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
GT348_RS06660	ENOG4108ESX	Receptor
GT348_RS06665	ENOG4107E2E	PKHD-type hydroxylase
GT348_RS06675	ENOG4108ZZF	transport protein (ExbD)
GT348_RS06685	ENOG4108Z6B	deaminase
GT348_RS06690	ENOG4105FE9	pseudouridine synthase
GT348_RS06695	ENOG4106H78	methyltransferase
GT348_RS06715	ENOG41069NU	Nitroreductase
GT348_RS06720	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
GT348_RS06725	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
GT348_RS06730	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
GT348_RS06735	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
GT348_RS06740	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
GT348_RS06745	ENOG4105K59	histidine triad (HIT) protein
GT348_RS06780	ENOG4107YSK	Glycerol-3-phosphate cytidylyltransferase
GT348_RS06800	ENOG4108RXX	maleylacetoacetate isomerase
GT348_RS06820	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GT348_RS06825	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
GT348_RS06835	ENOG4105CPC	Aldo Keto reductase
GT348_RS06840	ENOG4105ETX	regulatoR
GT348_RS06845	ENOG4105DHQ	Histidine kinase
GT348_RS06865	ENOG4105CQ7	ATP-dependent helicase
GT348_RS06875	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
GT348_RS06880	ENOG4105F8J	Adenylate Guanylate cyclase
GT348_RS06900	ENOG4105F9N	Major Facilitator Superfamily
GT348_RS06905	ENOG4108URH	decarboxylase
GT348_RS06910	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
GT348_RS06915	ENOG4105DHP	deoxycytidine triphosphate deaminase
GT348_RS06925	ENOG4105CPK	Glycosyl transferase (Group 1
GT348_RS06935	ENOG4105CFG	Acts as a chaperone (By similarity)
GT348_RS06940	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
GT348_RS06945	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
GT348_RS06950	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
GT348_RS06955	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
GT348_RS06960	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
GT348_RS06965	ENOG4105BZJ	Electron transfer flavoprotein
GT348_RS06970	ENOG4105C10	Electron transfer flavoprotein
GT348_RS06985	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
GT348_RS06990	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
GT348_RS07000	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
GT348_RS07010	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
GT348_RS07020	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
GT348_RS07035	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
GT348_RS07040	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
GT348_RS07065	ENOG4106YXT	transposase
GT348_RS07070	ENOG4108WTW	DNA transposition protein
GT348_RS07120	ENOG4105CF2	Mu-like prophage FluMu protein GP28
GT348_RS07215	ENOG4105EFV	Major head subunit
GT348_RS07240	ENOG4105TKZ	Tail Sheath
GT348_RS07330	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
GT348_RS07335	ENOG4105KVH	Transcriptional regulator
GT348_RS07365	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
GT348_RS07370	ENOG4108JQC	penicillin-binding protein 1A
GT348_RS07410	ENOG4105D8X	mechanosensitive ion channel
GT348_RS07425	ENOG4105D01	(LipO)protein
GT348_RS07455	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
GT348_RS07460	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
GT348_RS07475	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
GT348_RS07480	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
GT348_RS07485	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
GT348_RS07510	ENOG4105YK5	50S ribosomal protein L36
GT348_RS07530	ENOG4105Z26	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
GT348_RS07590	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GT348_RS07595	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
GT348_RS07610	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
GT348_RS07615	ENOG4105EUJ	GTP cyclohydrolase i
GT348_RS07620	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GT348_RS07625	ENOG4105EEI	dihydropteroate synthase
GT348_RS07630	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
GT348_RS07635	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
GT348_RS07640	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
GT348_RS07650	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
GT348_RS07660	ENOG4105D6E	homoserine dehydrogenase
GT348_RS07670	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
GT348_RS07750	ENOG4105HDK	L-asparaginase
GT348_RS07775	ENOG4108BUD	transposase
GT348_RS07805	ENOG4105CKK	Glycosyl transferase, family 2
GT348_RS07810	ENOG4105C54	Major Facilitator superfamily
GT348_RS07815	ENOG4105DEI	Mannitol dehydrogenase
GT348_RS07820	ENOG4108QY0	Membrane
GT348_RS07825	ENOG4105C2I	pirin domain protein
GT348_RS07835	ENOG4108UUM	single-stranded DNA-binding protein
GT348_RS07860	ENOG4105C72	UPF0176 protein
GT348_RS07865	ENOG4105BZU	Histidine kinase
GT348_RS07890	ENOG4107RCI	amp-dependent synthetase and ligase
GT348_RS07915	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
GT348_RS07965	ENOG4105C11	sulfate adenylyltransferase), subunit 2
GT348_RS07970	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
GT348_RS07985	ENOG4105DHJ	ABC, transporter
GT348_RS08005	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
GT348_RS08050	ENOG4105E2X	shikimate dehydrogenase
GT348_RS08060	ENOG4108R6W	Transcriptional regulator, ARAC family
GT348_RS08065	ENOG4105C59	p-type ATPase
GT348_RS08075	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
GT348_RS08080	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
GT348_RS08090	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
GT348_RS08095	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
GT348_RS08100	ENOG4105Z85	coenzyme PQQ synthesis
GT348_RS08105	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
GT348_RS08110	ENOG4105X1N	Glycosyl transferase family 8
GT348_RS08120	ENOG4105X1N	Glycosyl transferase family 8
GT348_RS08125	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
GT348_RS08135	ENOG4108R6K	riboflavin synthase, subunit alpha
GT348_RS08140	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
GT348_RS08150	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
GT348_RS08170	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
GT348_RS08180	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
GT348_RS08200	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
GT348_RS08205	ENOG4108Z03	MAF-like protein
GT348_RS08215	ENOG4105VYE	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
GT348_RS08225	ENOG4105CV8	reductase
GT348_RS08235	ENOG4105DHU	Bile acid
GT348_RS08240	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
GT348_RS08260	ENOG4107VRP	DNA repair exonuclease
GT348_RS08265	ENOG4106D4I	domain protein
GT348_RS08275	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
GT348_RS08285	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
GT348_RS08320	ENOG4108YXA	Membrane
GT348_RS08330	ENOG4105D5K	Hemolysin activator protein
GT348_RS08335	ENOG4105CKT	filamentous hemagglutinin
GT348_RS08345	ENOG4105CKT	filamentous hemagglutinin
GT348_RS08405	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
GT348_RS08410	ENOG4108UHJ	MAF-like protein
GT348_RS08425	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
GT348_RS08445	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
GT348_RS08460	ENOG4108S55	polysaccharide biosynthesis protein
GT348_RS08470	ENOG4106FPV	ATP-binding protein YghR
GT348_RS08475	ENOG4108GH0	ATP-binding protein yghT
GT348_RS08485	ENOG4105FA0	parb-like partition protein
GT348_RS08490	ENOG4107QJE	Chromosome Partitioning Protein
GT348_RS08495	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
GT348_RS08500	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
GT348_RS08505	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
GT348_RS08510	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
GT348_RS08520	ENOG4105C7S	Dehydrogenase
GT348_RS08530	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
GT348_RS08550	ENOG4105CEN	a g-specific adenine glycosylase
GT348_RS08560	ENOG4105EAC	phosphoserine phosphatase
GT348_RS08565	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
GT348_RS08575	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
GT348_RS08580	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
GT348_RS08585	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
GT348_RS08590	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
GT348_RS08600	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
GT348_RS08605	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GT348_RS08615	ENOG4105DKQ	ROK family
GT348_RS08620	ENOG4105C5F	glutamine synthetase
GT348_RS08625	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
GT348_RS08655	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
GT348_RS08660	ENOG4105CKK	Glycosyl transferase, family 2
GT348_RS08665	ENOG4108733	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GT348_RS08670	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
GT348_RS08680	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
GT348_RS08780	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
GT348_RS08870	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
GT348_RS08885	ENOG4105KTQ	flagellar basal-body rod protein
GT348_RS08890	ENOG4105CGA	flagellar basal-body rod protein FlgG
GT348_RS08900	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GT348_RS08920	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
GT348_RS08925	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
GT348_RS08935	ENOG4105DD5	Flagellar motor switch protein
GT348_RS08945	ENOG4105CN7	Flagellar biosynthetic protein FliP
GT348_RS08955	ENOG4105D7B	Flagellar biosynthesis protein flha
GT348_RS08970	ENOG4107S6X	Glycosyl transferase, family 2
GT348_RS08980	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
GT348_RS09010	ENOG4108JIR	Flagellum-specific ATP synthase
GT348_RS09025	ENOG4105ER2	Ompa motb domain protein
GT348_RS09030	ENOG4107RD7	Flagellar Motor Protein, MotA
GT348_RS09055	ENOG4105BZE	flagellar hook protein, FlgE
GT348_RS09060	ENOG4105D00	flagellar biosynthetic protein flhB
GT348_RS09070	ENOG4105VS8	Flagellar biosynthetic protein fliq
GT348_RS09075	ENOG4105UVF	flagellar hook-basal body complex protein fliE
GT348_RS09090	ENOG41083MZ	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
GT348_RS09095	ENOG4108ZC9	flagellar basal-body rod protein flgc
GT348_RS09115	ENOG4105FA0	parb-like partition protein
GT348_RS09120	ENOG4107QJE	Chromosome Partitioning Protein
GT348_RS09145	ENOG4107W75	Flagellin