locus-tag	class	description
DS830_RS00025	COG1388	LysM domain
DS830_RS00025	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS830_RS00040	COG1388	LysM domain
DS830_RS00040	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS830_RS00065	COG0628	permease
DS830_RS00075	COG0588	phosphoglycerate mutase activity
DS830_RS00085	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DS830_RS00090	COG0351	phosphomethylpyrimidine kinase
DS830_RS00105	COG0436	Aminotransferase
DS830_RS00115	COG0463	Glycosyl transferase, family 2
DS830_RS00120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DS830_RS00145	COG2271	Major facilitator Superfamily
DS830_RS00150	COG3250	beta-galactosidase activity
DS830_RS00170	COG1114	Component of the transport system for branched-chain amino acids
DS830_RS00175	COG3973	AAA domain
DS830_RS00190	COG0737	Belongs to the 5'-nucleotidase family
DS830_RS00220	COG2814	Major facilitator Superfamily
DS830_RS00235	COG1881	PFAM PEBP family protein
DS830_RS00245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DS830_RS00255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS830_RS00255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS830_RS00260	COG0084	hydrolase, TatD family'
DS830_RS00265	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DS830_RS00270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DS830_RS00275	COG4466	Protein conserved in bacteria
DS830_RS00280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS830_RS00285	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DS830_RS00290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DS830_RS00305	COG1078	dGTPase activity
DS830_RS00310	COG0095	Lipoate-protein ligase
DS830_RS00320	COG3343	RNA polymerase activity
DS830_RS00330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DS830_RS00340	COG1376	ErfK ybiS ycfS ynhG family protein
DS830_RS00350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DS830_RS00365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DS830_RS00375	COG2337	Toxic component of a toxin-antitoxin (TA) module
DS830_RS00385	COG0039	L-malate dehydrogenase activity
DS830_RS00390	COG0193	aminoacyl-tRNA hydrolase activity
DS830_RS00395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DS830_RS00400	COG2244	polysaccharide biosynthetic process
DS830_RS00405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DS830_RS00415	COG1098	S1 RNA binding domain
DS830_RS00420	COG0037	tRNA processing
DS830_RS00435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DS830_RS00440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DS830_RS00445	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DS830_RS00485	COG0542	response to heat
DS830_RS00505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DS830_RS00510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DS830_RS00515	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DS830_RS00530	COG0051	transcription antitermination factor activity, RNA binding
DS830_RS00535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DS830_RS00540	COG0088	Forms part of the polypeptide exit tunnel
DS830_RS00545	COG0089	rRNA binding
DS830_RS00550	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DS830_RS00565	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DS830_RS00570	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DS830_RS00580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DS830_RS00585	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DS830_RS00590	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DS830_RS00595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DS830_RS00610	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DS830_RS00615	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DS830_RS00620	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DS830_RS00630	COG0200	Binds to the 23S rRNA
DS830_RS00650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DS830_RS00655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DS830_RS00670	COG0203	ribosomal protein L17
DS830_RS00680	COG1122	ATPase activity
DS830_RS00695	COG0101	tRNA pseudouridine synthase activity
DS830_RS00700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DS830_RS00705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DS830_RS00710	COG1846	Transcriptional regulator
DS830_RS00715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS830_RS00775	COG0588	phosphoglycerate mutase activity
DS830_RS00805	COG0756	dUTP diphosphatase activity
DS830_RS00810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DS830_RS00815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DS830_RS00820	COG0215	cysteine-tRNA ligase activity
DS830_RS00825	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DS830_RS00830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DS830_RS00835	COG3688	RNA-binding protein containing a PIN domain
DS830_RS00840	COG1686	Belongs to the peptidase S11 family
DS830_RS00860	COG0250	Participates in transcription elongation, termination and antitermination
DS830_RS00865	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DS830_RS00870	COG0081	regulation of translation
DS830_RS00875	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DS830_RS00880	COG0222	ribosome binding
DS830_RS00890	COG2813	Specifically methylates the guanine in position
DS830_RS00895	COG0590	tRNA wobble adenosine to inosine editing
DS830_RS00905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DS830_RS00910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DS830_RS00925	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DS830_RS00935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DS830_RS00940	COG3870	Protein conserved in bacteria
DS830_RS00945	COG0470	DNA polymerase III
DS830_RS00965	COG1418	mRNA catabolic process
DS830_RS00980	COG0745	RESPONSE REGULATOR receiver
DS830_RS00985	COG5002	protein histidine kinase activity
DS830_RS00990	COG1136	(ABC) transporter
DS830_RS01000	COG0577	efflux transmembrane transporter activity
DS830_RS01005	COG1396	sequence-specific DNA binding
DS830_RS01025	COG3655	Transcriptional regulator
DS830_RS01035	COG1228	amidohydrolase
DS830_RS01055	COG1136	(ABC) transporter
DS830_RS01070	COG1214	PFAM Peptidase M22, glycoprotease
DS830_RS01075	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DS830_RS01085	COG3715	PTS system
DS830_RS01090	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS01100	COG0488	(ABC) transporter
DS830_RS01110	COG1482	cell wall glycoprotein biosynthetic process
DS830_RS01115	COG1368	sulfuric ester hydrolase activity
DS830_RS01135	COG1692	metallophosphoesterase
DS830_RS01140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DS830_RS01150	COG0632	four-way junction helicase activity
DS830_RS01155	COG2255	four-way junction helicase activity
DS830_RS01160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DS830_RS01165	COG0343	queuine tRNA-ribosyltransferase activity
DS830_RS01170	COG1862	Preprotein translocase
DS830_RS01175	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DS830_RS01180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS830_RS01185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DS830_RS01190	COG0513	Belongs to the DEAD box helicase family
DS830_RS01205	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DS830_RS01225	COG3118	belongs to the thioredoxin family
DS830_RS01235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DS830_RS01240	COG1696	Membrane protein involved in D-alanine export
DS830_RS01245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS830_RS01250	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DS830_RS01255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DS830_RS01260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DS830_RS01265	COG0668	transmembrane transport
DS830_RS01285	COG2205	protein histidine kinase activity
DS830_RS01290	COG1136	(ABC) transporter
DS830_RS01310	COG1609	Transcriptional regulator
DS830_RS01320	COG2814	Major facilitator Superfamily
DS830_RS01330	COG0584	glycerophosphoryl diester phosphodiesterase
DS830_RS01340	COG0737	Belongs to the 5'-nucleotidase family
DS830_RS01345	COG4470	Protein conserved in bacteria
DS830_RS01350	COG0647	UMP catabolic process
DS830_RS01360	COG0586	Pfam SNARE associated Golgi protein
DS830_RS01365	COG0492	ferredoxin-NADP+ reductase activity
DS830_RS01370	COG0539	negative regulation of cytoplasmic translation
DS830_RS01530	COG1428	Deoxynucleoside kinase
DS830_RS01535	COG0438	transferase activity, transferring glycosyl groups
DS830_RS01540	COG0438	transferase activity, transferring glycosyl groups
DS830_RS01550	COG1368	sulfuric ester hydrolase activity
DS830_RS01555	COG0735	belongs to the Fur family
DS830_RS01620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DS830_RS01625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DS830_RS01630	COG0477	Major facilitator Superfamily
DS830_RS01640	COG3942	CHAP domain
DS830_RS01640	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS830_RS01645	COG0495	leucyl-tRNA aminoacylation
DS830_RS01650	COG2244	polysaccharide biosynthetic process
DS830_RS01655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DS830_RS01660	COG0514	ATP-dependent DNA helicase (RecQ)
DS830_RS01665	COG1396	sequence-specific DNA binding
DS830_RS01730	COG0018	arginyl-trna synthetase
DS830_RS01740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS830_RS01745	COG3679	Belongs to the UPF0342 family
DS830_RS01750	COG0420	3'-5' exonuclease activity
DS830_RS01755	COG4717	serine-type aminopeptidase activity
DS830_RS01760	COG3481	metal-dependent phosphohydrolase, HD sub domain
DS830_RS01765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DS830_RS01775	COG0537	adenosine 5'-monophosphoramidase activity
DS830_RS01780	COG1131	(ABC) transporter
DS830_RS01800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DS830_RS01805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DS830_RS01820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS830_RS01820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DS830_RS01830	COG0237	dephospho-CoA kinase activity
DS830_RS01835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DS830_RS01840	COG3611	Membrane attachment protein
DS830_RS01845	COG1484	DNA-dependent DNA replication
DS830_RS01855	COG0737	Belongs to the 5'-nucleotidase family
DS830_RS01860	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS830_RS01875	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DS830_RS01885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DS830_RS01890	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DS830_RS01895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DS830_RS01905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DS830_RS01910	COG1713	HD superfamily hydrolase involved in NAD metabolism
DS830_RS01915	COG0799	negative regulation of ribosome biogenesis
DS830_RS01920	COG1323	Belongs to the UPF0348 family
DS830_RS01930	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DS830_RS01935	COG0745	RESPONSE REGULATOR receiver
DS830_RS01940	COG5002	protein histidine kinase activity
DS830_RS01955	COG0706	membrane insertase activity
DS830_RS01965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DS830_RS01980	COG0072	phenylalanine-tRNA ligase activity
DS830_RS01985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DS830_RS01990	COG0572	uridine kinase
DS830_RS01995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DS830_RS02005	COG0768	penicillin binding
DS830_RS02010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DS830_RS02015	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DS830_RS02020	COG0705	Rhomboid family
DS830_RS02020	COG0457	Tetratricopeptide repeat
DS830_RS02030	COG1940	carbohydrate kinase activity
DS830_RS02035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DS830_RS02045	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DS830_RS02050	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
DS830_RS02055	COG0789	Transcriptional regulator
DS830_RS02070	COG0582	viral genome integration into host DNA
DS830_RS02085	COG2249	NAD(P)H dehydrogenase (quinone) activity
DS830_RS02100	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DS830_RS02110	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DS830_RS02115	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DS830_RS02125	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS830_RS02135	COG1570	exodeoxyribonuclease VII activity
DS830_RS02140	COG1722	exodeoxyribonuclease VII activity
DS830_RS02150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DS830_RS02155	COG0497	DNA recombination
DS830_RS02160	COG0194	GDP metabolic process
DS830_RS02165	COG1758	RNA polymerase activity
DS830_RS02170	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DS830_RS02175	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DS830_RS02180	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DS830_RS02180	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DS830_RS02190	COG2815	serine threonine protein kinase
DS830_RS02190	COG0515	serine threonine protein kinase
DS830_RS02195	COG1162	GTPase activity
DS830_RS02200	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DS830_RS02205	COG1564	THIamine pyrophosphokinase
DS830_RS02210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DS830_RS02215	COG1302	Protein conserved in bacteria
DS830_RS02220	COG1461	Dihydroxyacetone kinase
DS830_RS02225	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DS830_RS02230	COG0416	fatty acid biosynthetic process
DS830_RS02235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DS830_RS02240	COG0571	ribonuclease III activity
DS830_RS02245	COG1196	nuclear chromosome segregation
DS830_RS02250	COG0552	protein localization to endoplasmic reticulum
DS830_RS02255	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DS830_RS02260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DS830_RS02265	COG0228	four-way junction DNA binding
DS830_RS02270	COG1837	Belongs to the UPF0109 family
DS830_RS02275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DS830_RS02290	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DS830_RS02295	COG4224	UPF0291 protein
DS830_RS02305	COG1132	(ABC) transporter
DS830_RS02310	COG1132	(ABC) transporter
DS830_RS02315	COG0204	Acyl-transferase
DS830_RS02320	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DS830_RS02325	COG2827	Endonuclease containing a URI domain
DS830_RS02350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DS830_RS02355	COG4589	Belongs to the CDS family
DS830_RS02360	COG0750	zinc metalloprotease
DS830_RS02365	COG0442	prolyl-tRNA aminoacylation
DS830_RS02370	COG2176	DNA-directed DNA polymerase activity
DS830_RS02375	COG0779	Required for maturation of 30S ribosomal subunits
DS830_RS02380	COG0195	Participates in both transcription termination and antitermination
DS830_RS02385	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DS830_RS02395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DS830_RS02395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DS830_RS02400	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DS830_RS02405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DS830_RS02410	COG0196	riboflavin kinase activity
DS830_RS02420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DS830_RS02425	COG0443	Heat shock 70 kDa protein
DS830_RS02445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DS830_RS02445	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DS830_RS02515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DS830_RS02530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS02530	COG1263	PTS System
DS830_RS02530	COG2190	(PTS) system
DS830_RS02540	COG2190	(PTS) system
DS830_RS02540	COG1263	PTS System
DS830_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS02555	COG4690	dipeptidase activity
DS830_RS02570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DS830_RS02580	COG2264	protein methyltransferase activity
DS830_RS02585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DS830_RS02595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DS830_RS02600	COG1490	D-aminoacyl-tRNA deacylase activity
DS830_RS02605	COG0546	phosphoglycolate phosphatase activity
DS830_RS02610	COG3103	Sh3 type 3 domain protein
DS830_RS02610	COG4991	sh3 domain protein
DS830_RS02610	COG0860	N-Acetylmuramoyl-L-alanine amidase
DS830_RS02615	COG0124	histidyl-tRNA synthetase
DS830_RS02630	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DS830_RS02635	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DS830_RS02640	COG2267	carboxylic ester hydrolase activity
DS830_RS02645	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DS830_RS02650	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DS830_RS02655	COG1610	YqeY-like protein
DS830_RS02660	COG1702	phosphate starvation-inducible protein PhoH
DS830_RS02680	COG1381	Involved in DNA repair and RecF pathway recombination
DS830_RS02685	COG0752	glycyl-tRNA synthetase alpha subunit
DS830_RS02690	COG0751	glycine-tRNA ligase activity
DS830_RS02695	COG0358	DNA primase activity
DS830_RS02700	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DS830_RS02705	COG2384	SAM-dependent methyltransferase
DS830_RS02710	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DS830_RS02715	COG2195	Cleaves the N-terminal amino acid of tripeptides
DS830_RS02720	COG1942	4-Oxalocrotonate Tautomerase
DS830_RS02725	COG0308	aminopeptidase N
DS830_RS02730	COG2390	Transcriptional regulator
DS830_RS02735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DS830_RS02740	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DS830_RS02750	COG0813	purine-nucleoside phosphorylase activity
DS830_RS02755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS830_RS02775	COG1131	(ABC) transporter
DS830_RS02805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DS830_RS02820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DS830_RS02825	COG0789	Transcriptional regulator
DS830_RS02855	COG1396	sequence-specific DNA binding
DS830_RS02865	COG0655	NAD(P)H dehydrogenase (quinone) activity
DS830_RS02900	COG0577	efflux transmembrane transporter activity
DS830_RS02970	COG1396	sequence-specific DNA binding
DS830_RS02975	COG1131	(ABC) transporter
DS830_RS03005	COG1181	Belongs to the D-alanine--D-alanine ligase family
DS830_RS03020	COG1131	(ABC) transporter
DS830_RS03030	COG1396	sequence-specific DNA binding
DS830_RS03035	COG1131	(ABC) transporter
DS830_RS03055	COG2814	Major facilitator Superfamily
DS830_RS03060	COG0667	Aldo Keto reductase
DS830_RS03070	COG1131	(ABC) transporter
DS830_RS03075	COG1132	(ABC) transporter
DS830_RS03085	COG3279	Response regulator of the LytR AlgR family
DS830_RS03105	COG1136	(ABC) transporter
DS830_RS03120	COG2814	Major facilitator Superfamily
DS830_RS03150	COG1250	3-hydroxyacyl-CoA dehydrogenase
DS830_RS03175	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DS830_RS03185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DS830_RS03185	COG1199	ATP-dependent helicase activity
DS830_RS03195	COG0017	Asparaginyl-tRNA synthetase
DS830_RS03205	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DS830_RS03210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS830_RS03220	COG4474	Belongs to the UPF0398 family
DS830_RS03235	COG0116	Belongs to the methyltransferase superfamily
DS830_RS03250	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DS830_RS03260	COG0564	pseudouridine synthase activity
DS830_RS03270	COG0505	Belongs to the CarA family
DS830_RS03280	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DS830_RS03285	COG1307	EDD domain protein, DegV family
DS830_RS03290	COG2814	Major facilitator Superfamily
DS830_RS03295	COG4166	transmembrane transport
DS830_RS03300	COG2267	carboxylic ester hydrolase activity
DS830_RS03305	COG4974	Belongs to the 'phage' integrase family
DS830_RS03310	COG0577	efflux transmembrane transporter activity
DS830_RS03310	COG1136	(ABC) transporter
DS830_RS03330	COG0583	DNA-binding transcription factor activity
DS830_RS03335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DS830_RS03340	COG0187	DNA topoisomerase II activity
DS830_RS03345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DS830_RS03350	COG2011	ABC-type metal ion transport system permease component
DS830_RS03355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DS830_RS03365	COG1464	Belongs to the NlpA lipoprotein family
DS830_RS03390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DS830_RS03395	COG0758	DNA mediated transformation
DS830_RS03400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DS830_RS03410	COG3409	Peptidoglycan-binding domain 1 protein
DS830_RS03410	COG0793	Belongs to the peptidase S41A family
DS830_RS03420	COG4698	Protein conserved in bacteria
DS830_RS03430	COG1307	EDD domain protein, DegV family
DS830_RS03435	COG1272	protein, Hemolysin III
DS830_RS03440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DS830_RS03445	COG0488	(ABC) transporter
DS830_RS03450	COG0617	tRNA 3'-terminal CCA addition
DS830_RS03455	COG0457	Tetratricopeptide repeat
DS830_RS03470	COG0539	negative regulation of cytoplasmic translation
DS830_RS03475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DS830_RS03485	COG1187	pseudouridine synthase activity
DS830_RS03490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DS830_RS03495	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DS830_RS03530	COG0587	DNA-directed DNA polymerase activity
DS830_RS03550	COG0300	oxidoreductase activity
DS830_RS03555	COG1234	tRNA 3'-trailer cleavage
DS830_RS03560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DS830_RS03560	COG2755	lipolytic protein G-D-S-L family
DS830_RS03565	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DS830_RS03570	COG1349	DNA-binding transcription factor activity
DS830_RS03575	COG1105	Belongs to the carbohydrate kinase PfkB family
DS830_RS03580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS830_RS03580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS03580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DS830_RS03585	COG3142	Participates in the control of copper homeostasis
DS830_RS03595	COG0322	excinuclease ABC activity
DS830_RS03600	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DS830_RS03605	COG1461	Dihydroxyacetone kinase
DS830_RS03610	COG2376	Dihydroxyacetone kinase
DS830_RS03615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DS830_RS03620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DS830_RS03650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DS830_RS03660	COG1466	dna polymerase III delta subunit
DS830_RS03665	COG0658	competence protein
DS830_RS03665	COG2333	competence protein COMEC
DS830_RS03670	COG1555	photosystem II stabilization
DS830_RS03670	COG1596	polysaccharide export
DS830_RS03675	COG3480	Lon protease (S16) C-terminal proteolytic domain
DS830_RS03680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DS830_RS03685	COG0742	ribosomal rna small subunit methyltransferase
DS830_RS03695	COG0772	Belongs to the SEDS family
DS830_RS03700	COG1217	gtp-binding protein TYPA
DS830_RS03705	COG0483	inositol monophosphate 1-phosphatase activity
DS830_RS03730	COG0242	peptide deformylase activity
DS830_RS03740	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DS830_RS03745	COG1597	lipid kinase activity
DS830_RS03750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DS830_RS03760	COG0406	alpha-ribazole phosphatase activity
DS830_RS03765	COG0482	sulfurtransferase activity
DS830_RS03775	COG1104	cysteine desulfurase activity
DS830_RS03800	COG1278	Cold shock
DS830_RS03805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DS830_RS03810	COG3599	regulation of cell shape
DS830_RS03815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DS830_RS03830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DS830_RS03845	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DS830_RS03850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DS830_RS03855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DS830_RS03860	COG0768	penicillin binding
DS830_RS03885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS830_RS03890	COG1126	abc transporter atp-binding protein
DS830_RS03895	COG0765	amino acid transport
DS830_RS03900	COG2894	cell division
DS830_RS03905	COG0850	regulation of cytokinetic process
DS830_RS03915	COG1792	Involved in formation and maintenance of cell shape
DS830_RS03920	COG1077	Cell shape determining protein MreB Mrl
DS830_RS03925	COG2003	Belongs to the UPF0758 family
DS830_RS03935	COG0525	valine-tRNA ligase activity
DS830_RS03945	COG1104	cysteine desulfurase activity
DS830_RS03950	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DS830_RS03955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DS830_RS03960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DS830_RS03970	COG0589	response to stress
DS830_RS03975	COG0772	Belongs to the SEDS family
DS830_RS03985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DS830_RS03995	COG1077	Cell shape determining protein MreB Mrl
DS830_RS04010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DS830_RS04025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DS830_RS04030	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DS830_RS04035	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DS830_RS04040	COG0356	it plays a direct role in the translocation of protons across the membrane
DS830_RS04050	COG0009	L-threonylcarbamoyladenylate synthase
DS830_RS04055	COG2890	protein-(glutamine-N5) methyltransferase activity
DS830_RS04060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DS830_RS04065	COG1435	thymidine kinase activity
DS830_RS04070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DS830_RS04085	COG1131	(ABC) transporter
DS830_RS04090	COG4585	Histidine kinase
DS830_RS04095	COG2197	response regulator
DS830_RS04100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DS830_RS04105	COG1132	(ABC) transporter
DS830_RS04135	COG0531	amino acid
DS830_RS04155	COG1285	pathogenesis
DS830_RS04175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DS830_RS04180	COG0436	Aminotransferase
DS830_RS04185	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DS830_RS04190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DS830_RS04195	COG1473	amidohydrolase
DS830_RS04200	COG2171	N-acyltransferase activity
DS830_RS04205	COG0019	diaminopimelate decarboxylase activity
DS830_RS04210	COG0527	aspartate kinase activity
DS830_RS04215	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DS830_RS04220	COG2936	dipeptidyl-peptidase activity
DS830_RS04225	COG0531	amino acid
DS830_RS04235	COG0463	Glycosyl transferase, family 2
DS830_RS04250	COG1368	sulfuric ester hydrolase activity
DS830_RS04255	COG5002	protein histidine kinase activity
DS830_RS04255	COG3850	Histidine kinase
DS830_RS04260	COG0745	RESPONSE REGULATOR receiver
DS830_RS04265	COG0561	phosphatase activity
DS830_RS04295	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DS830_RS04300	COG0827	DNA restriction-modification system
DS830_RS04330	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DS830_RS04345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DS830_RS04365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DS830_RS04375	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DS830_RS04380	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DS830_RS04390	COG0802	atpase or kinase
DS830_RS04395	COG0280	phosphate acetyltransferase
DS830_RS04400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DS830_RS04405	COG0561	phosphatase activity
DS830_RS04430	COG0557	exoribonuclease II activity
DS830_RS04440	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DS830_RS04455	COG0148	phosphopyruvate hydratase activity
DS830_RS04495	COG0431	NADPH-dependent FMN reductase
DS830_RS04500	COG0740	serine-type endopeptidase activity
DS830_RS04505	COG0446	pyridine nucleotide-disulphide oxidoreductase
DS830_RS04510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DS830_RS04535	COG4166	transmembrane transport
DS830_RS04540	COG0738	Major facilitator superfamily
DS830_RS04545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DS830_RS04555	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DS830_RS04560	COG0287	Prephenate dehydrogenase
DS830_RS04565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DS830_RS04570	COG2197	response regulator
DS830_RS04575	COG4585	Histidine kinase
DS830_RS04585	COG1131	(ABC) transporter
DS830_RS04590	COG2365	Tyrosine phosphatase family
DS830_RS04615	COG0702	epimerase
DS830_RS04620	COG1481	regulation of sporulation
DS830_RS04630	COG1660	Displays ATPase and GTPase activities
DS830_RS04635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DS830_RS04650	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DS830_RS04655	COG0492	ferredoxin-NADP+ reductase activity
DS830_RS04660	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DS830_RS04670	COG1950	PFAM Membrane protein of
DS830_RS04675	COG0704	Plays a role in the regulation of phosphate uptake
DS830_RS04680	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS830_RS04685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DS830_RS04690	COG0581	inorganic phosphate transmembrane transporter activity
DS830_RS04695	COG0573	inorganic phosphate transmembrane transporter activity
DS830_RS04705	COG5002	protein histidine kinase activity
DS830_RS04710	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DS830_RS04720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DS830_RS04730	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DS830_RS04735	COG1739	Uncharacterized protein family UPF0029
DS830_RS04740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DS830_RS04760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DS830_RS04765	COG1426	Protein conserved in bacteria
DS830_RS04770	COG0300	oxidoreductase activity
DS830_RS04775	COG0612	Peptidase, M16
DS830_RS04780	COG0612	Peptidase, M16
DS830_RS04785	COG1674	ftsk spoiiie
DS830_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
DS830_RS04800	COG4708	membrane
DS830_RS04810	COG1091	dTDP-4-dehydrorhamnose reductase activity
DS830_RS04815	COG1088	dTDP-glucose 4,6-dehydratase activity
DS830_RS04825	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DS830_RS04865	COG1215	transferase activity, transferring glycosyl groups
DS830_RS04870	COG0463	Glycosyl transferase, family 2
DS830_RS04900	COG0628	permease
DS830_RS04910	COG2706	6-phosphogluconolactonase activity
DS830_RS04915	COG1968	undecaprenyl-diphosphatase activity
DS830_RS04920	COG2239	Acts as a magnesium transporter
DS830_RS04925	COG0564	pseudouridine synthase activity
DS830_RS04935	COG2357	RelA SpoT domain protein
DS830_RS04950	COG4862	establishment of competence for transformation
DS830_RS04955	COG1393	Belongs to the ArsC family
DS830_RS04960	COG1234	tRNA 3'-trailer cleavage
DS830_RS04970	COG2217	Heavy metal translocating P-type atpase
DS830_RS04995	COG0542	response to heat
DS830_RS05005	COG0577	efflux transmembrane transporter activity
DS830_RS05005	COG1136	(ABC) transporter
DS830_RS05025	COG1131	(ABC) transporter
DS830_RS05035	COG1695	Transcriptional regulator
DS830_RS05050	COG0406	alpha-ribazole phosphatase activity
DS830_RS05070	COG3557	Belongs to the UPF0374 family
DS830_RS05075	COG2137	regulation of response to DNA damage stimulus
DS830_RS05080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DS830_RS05085	COG3425	synthase
DS830_RS05095	COG0183	Belongs to the thiolase family
DS830_RS05105	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DS830_RS05115	COG0024	Methionine aminopeptidase
DS830_RS05120	COG0716	FMN binding
DS830_RS05130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DS830_RS05145	COG0673	inositol 2-dehydrogenase activity
DS830_RS05160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DS830_RS05180	COG0604	alcohol dehydrogenase
DS830_RS05185	COG1733	regulation of RNA biosynthetic process
DS830_RS05200	COG0640	Transcriptional regulator
DS830_RS05205	COG2217	Heavy metal translocating P-type atpase
DS830_RS05210	COG4166	transmembrane transport
DS830_RS05225	COG1309	transcriptional regulator
DS830_RS05245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS830_RS05255	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DS830_RS05260	COG1597	lipid kinase activity
DS830_RS05265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS830_RS05270	COG0154	amidase activity
DS830_RS05275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DS830_RS05280	COG4851	CamS sex pheromone cAM373 precursor
DS830_RS05295	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DS830_RS05305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DS830_RS05310	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS830_RS05315	COG1278	Cold shock
DS830_RS05330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DS830_RS05335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DS830_RS05340	COG0438	transferase activity, transferring glycosyl groups
DS830_RS05355	COG2188	Transcriptional regulator
DS830_RS05370	COG3104	oligopeptide transport
DS830_RS05375	COG2094	Belongs to the DNA glycosylase MPG family
DS830_RS05410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DS830_RS05475	COG0438	transferase activity, transferring glycosyl groups
DS830_RS05480	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DS830_RS05490	COG2814	Major facilitator Superfamily
DS830_RS05500	COG2252	PERMEase
DS830_RS05505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DS830_RS05515	COG0167	dihydroorotate dehydrogenase activity
DS830_RS05520	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DS830_RS05525	COG0505	Belongs to the CarA family
DS830_RS05530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DS830_RS05535	COG0540	Belongs to the ATCase OTCase family
DS830_RS05540	COG2244	polysaccharide biosynthetic process
DS830_RS05550	COG0546	phosphoglycolate phosphatase activity
DS830_RS05560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DS830_RS05570	COG1464	Belongs to the NlpA lipoprotein family
DS830_RS05575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DS830_RS05580	COG0501	Belongs to the peptidase M48B family
DS830_RS05585	COG1704	LemA family
DS830_RS05590	COG3527	Alpha-acetolactate decarboxylase
DS830_RS05595	COG0028	Belongs to the TPP enzyme family
DS830_RS05620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS05625	COG0564	pseudouridine synthase activity
DS830_RS05640	COG0583	DNA-binding transcription factor activity
DS830_RS05670	COG1518	maintenance of DNA repeat elements
DS830_RS05675	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DS830_RS05680	COG0367	asparagine synthase
DS830_RS05705	COG1442	glycosyl transferase family 8
DS830_RS05710	COG0517	IMP dehydrogenase activity
DS830_RS05715	COG0410	ABC transporter
DS830_RS05720	COG0411	ABC transporter
DS830_RS05740	COG0509	glycine decarboxylation via glycine cleavage system
DS830_RS05745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DS830_RS05760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DS830_RS05770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DS830_RS05775	COG1126	abc transporter atp-binding protein
DS830_RS05780	COG0765	amino acid transport
DS830_RS05785	COG1012	belongs to the aldehyde dehydrogenase family
DS830_RS05790	COG1136	(ABC) transporter
DS830_RS05795	COG4120	Belongs to the binding-protein-dependent transport system permease family
DS830_RS05810	COG0789	Transcriptional regulator
DS830_RS05815	COG2226	methyltransferase
DS830_RS05835	COG0165	Argininosuccinate lyase
DS830_RS05855	COG2207	Transcriptional regulator
DS830_RS05860	COG3507	Belongs to the glycosyl hydrolase 43 family
DS830_RS05865	COG2211	Major facilitator Superfamily
DS830_RS05870	COG2115	Belongs to the xylose isomerase family
DS830_RS05900	COG0419	ATPase involved in DNA repair
DS830_RS05905	COG0420	3'-5' exonuclease activity
DS830_RS05910	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DS830_RS05955	COG2814	Major facilitator Superfamily
DS830_RS05960	COG2190	(PTS) system
DS830_RS05960	COG1263	PTS System
DS830_RS05960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS05965	COG2723	6-phospho-beta-galactosidase activity
DS830_RS05980	COG0561	phosphatase activity
DS830_RS05995	COG2814	Major facilitator Superfamily
DS830_RS06005	COG0519	Catalyzes the synthesis of GMP from XMP
DS830_RS06005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DS830_RS06010	COG0561	phosphatase activity
DS830_RS06025	COG1113	amino acid transport
DS830_RS06030	COG4221	oxidoreductase activity
DS830_RS06035	COG2723	6-phospho-beta-galactosidase activity
DS830_RS06040	COG0406	alpha-ribazole phosphatase activity
DS830_RS06050	COG3711	transcriptional antiterminator
DS830_RS06055	COG3507	Belongs to the glycosyl hydrolase 43 family
DS830_RS06060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DS830_RS06080	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS06085	COG2723	6-phospho-beta-galactosidase activity
DS830_RS06090	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DS830_RS06105	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS06110	COG3715	PTS system
DS830_RS06115	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS06120	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DS830_RS06120	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DS830_RS06150	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS06155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS06155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS06160	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS06180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DS830_RS06205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DS830_RS06210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DS830_RS06215	COG1609	Transcriptional regulator
DS830_RS06225	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS06245	COG3933	PFAM sigma-54 factor interaction domain-containing protein
DS830_RS06245	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DS830_RS06250	COG2807	transmembrane transport
DS830_RS06260	COG3973	AAA domain
DS830_RS06275	COG1131	(ABC) transporter
DS830_RS06285	COG2267	carboxylic ester hydrolase activity
DS830_RS06295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DS830_RS06315	COG3052	prosthetic group binding
DS830_RS06335	COG2267	carboxylic ester hydrolase activity
DS830_RS06340	COG0471	metal ion transport
DS830_RS06345	COG0039	L-malate dehydrogenase activity
DS830_RS06355	COG0114	fumarate hydratase activity
DS830_RS06380	COG0431	NADPH-dependent FMN reductase
DS830_RS06380	COG3976	FMN-binding domain protein
DS830_RS06380	COG1053	succinate dehydrogenase
DS830_RS06385	COG0431	NADPH-dependent FMN reductase
DS830_RS06385	COG3976	FMN-binding domain protein
DS830_RS06385	COG1053	succinate dehydrogenase
DS830_RS06390	COG0765	amino acid transport
DS830_RS06395	COG0765	amino acid transport
DS830_RS06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS830_RS06410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DS830_RS06425	COG0531	amino acid
DS830_RS06430	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DS830_RS06435	COG4166	transmembrane transport
DS830_RS06440	COG0601	transmembrane transport
DS830_RS06445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DS830_RS06450	COG0444	Belongs to the ABC transporter superfamily
DS830_RS06455	COG4608	Belongs to the ABC transporter superfamily
DS830_RS06490	COG0778	Nitroreductase
DS830_RS06495	COG2135	peptidase activity
DS830_RS06505	COG2814	Major facilitator Superfamily
DS830_RS06510	COG1278	Cold shock
DS830_RS06520	COG0194	GDP metabolic process
DS830_RS06535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DS830_RS06540	COG1780	Probably involved in ribonucleotide reductase function
DS830_RS06545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DS830_RS06570	COG0708	Exodeoxyribonuclease III
DS830_RS06590	COG3048	D-serine ammonia-lyase activity
DS830_RS06595	COG1113	amino acid transport
DS830_RS06600	COG1063	alcohol dehydrogenase
DS830_RS06620	COG4166	transmembrane transport
DS830_RS06625	COG0406	alpha-ribazole phosphatase activity
DS830_RS06630	COG2814	Major facilitator Superfamily
DS830_RS06645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS06680	COG0488	(ABC) transporter
DS830_RS06685	COG1316	TRANSCRIPTIONal
DS830_RS06695	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DS830_RS06705	COG0745	RESPONSE REGULATOR receiver
DS830_RS06745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DS830_RS06765	COG3844	kynureninase activity
DS830_RS06790	COG1396	sequence-specific DNA binding
DS830_RS06795	COG2217	Heavy metal translocating P-type atpase
DS830_RS06815	COG2723	6-phospho-beta-galactosidase activity
DS830_RS06895	COG0477	Major facilitator Superfamily
DS830_RS06910	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DS830_RS06920	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS06925	COG3715	PTS system
DS830_RS06930	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS06930	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS06940	COG2365	Tyrosine phosphatase family
DS830_RS06960	COG1349	DNA-binding transcription factor activity
DS830_RS06975	COG3775	system Galactitol-specific IIC component
DS830_RS06980	COG0235	Class ii aldolase
DS830_RS06985	COG2188	Transcriptional regulator
DS830_RS06990	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS06995	COG3715	PTS system
DS830_RS07010	COG2222	sugar isomerase
DS830_RS07040	COG0531	amino acid
DS830_RS07050	COG3534	alpha-L-arabinofuranosidase
DS830_RS07060	COG2207	Transcriptional regulator
DS830_RS07080	COG0656	L-ascorbic acid biosynthetic process
DS830_RS07085	COG2814	Major facilitator Superfamily
DS830_RS07090	COG0284	orotidine-5'-phosphate decarboxylase activity
DS830_RS07095	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DS830_RS07100	COG0406	alpha-ribazole phosphatase activity
DS830_RS07105	COG2233	PERMEase
DS830_RS07110	COG0277	FAD linked oxidase domain protein
DS830_RS07115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DS830_RS07120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DS830_RS07125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DS830_RS07130	COG1940	carbohydrate kinase activity
DS830_RS07135	COG2233	PERMEase
DS830_RS07145	COG0697	spore germination
DS830_RS07150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS830_RS07155	COG1169	isochorismate synthase
DS830_RS07160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DS830_RS07180	COG0531	amino acid
DS830_RS07185	COG0561	phosphatase activity
DS830_RS07200	COG2217	Heavy metal translocating P-type atpase
DS830_RS07205	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DS830_RS07255	COG1131	(ABC) transporter
DS830_RS07270	COG3279	Response regulator of the LytR AlgR family
DS830_RS07275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DS830_RS07280	COG2274	protein secretion by the type I secretion system
DS830_RS07285	COG1652	LysM domain
DS830_RS07285	COG2823	Periplasmic or secreted lipoprotein
DS830_RS07290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DS830_RS07295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DS830_RS07300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DS830_RS07315	COG5002	protein histidine kinase activity
DS830_RS07320	COG0745	RESPONSE REGULATOR receiver
DS830_RS07330	COG0765	amino acid transport
DS830_RS07335	COG1126	abc transporter atp-binding protein
DS830_RS07345	COG4990	cell redox homeostasis
DS830_RS07360	COG2246	polysaccharide biosynthetic process
DS830_RS07365	COG0531	amino acid
DS830_RS07370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DS830_RS07395	COG0305	Participates in initiation and elongation during chromosome replication
DS830_RS07400	COG1346	cytolysis
DS830_RS07410	COG3279	Response regulator of the LytR AlgR family
DS830_RS07415	COG3275	phosphorelay sensor kinase activity
DS830_RS07430	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DS830_RS07435	COG0629	single-stranded DNA binding
DS830_RS07440	COG0360	Binds together with S18 to 16S ribosomal RNA
DS830_RS07450	COG0187	DNA topoisomerase II activity
DS830_RS07455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DS830_RS07465	COG0592	DNA-directed DNA polymerase activity
DS830_RS07470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DS830_RS07475	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DS830_RS07485	COG0706	membrane insertase activity
DS830_RS07495	COG2271	Major facilitator Superfamily
DS830_RS07500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DS830_RS07505	COG0445	tRNA wobble uridine modification
DS830_RS07510	COG0363	glucosamine-6-phosphate deaminase activity
DS830_RS07530	COG1252	NADH dehydrogenase
DS830_RS07535	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DS830_RS07540	COG1609	Transcriptional regulator
DS830_RS07550	COG0142	geranyltranstransferase activity
DS830_RS07555	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DS830_RS07560	COG4988	ABC transporter
DS830_RS07565	COG1294	oxidase, subunit
DS830_RS07570	COG1271	oxidase subunit
DS830_RS07580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DS830_RS07585	COG1136	(ABC) transporter
DS830_RS07585	COG1136	(ABC) transporter
DS830_RS07585	COG0577	efflux transmembrane transporter activity
DS830_RS07585	COG0577	efflux transmembrane transporter activity
DS830_RS07590	COG2084	Dehydrogenase
DS830_RS07595	COG0351	phosphomethylpyrimidine kinase
DS830_RS07605	COG0670	Belongs to the BI1 family
DS830_RS07610	COG1263	PTS System
DS830_RS07610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS07610	COG2190	(PTS) system
DS830_RS07615	COG2188	Transcriptional regulator
DS830_RS07620	COG0366	Alpha amylase catalytic
DS830_RS07625	COG0833	amino acid
DS830_RS07630	COG4684	Psort location CytoplasmicMembrane, score
DS830_RS07635	COG2814	Major facilitator Superfamily
DS830_RS07640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DS830_RS07645	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DS830_RS07655	COG1501	Belongs to the glycosyl hydrolase 31 family
DS830_RS07665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS07680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DS830_RS07685	COG3442	glutamine amidotransferase
DS830_RS07695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DS830_RS07700	COG2502	aspartate--ammonia ligase
DS830_RS07720	COG0038	chloride channel
DS830_RS07735	COG0357	Ribosomal RNA small subunit methyltransferase G
DS830_RS07740	COG1475	DNA binding
DS830_RS07745	COG1192	Involved in chromosome partitioning
DS830_RS07750	COG1475	DNA binding
DS830_RS07755	COG4481	Protein conserved in bacteria
DS830_RS07760	COG0012	GTP binding
DS830_RS07770	COG1609	Transcriptional regulator
DS830_RS07790	COG1511	domain protein
DS830_RS07795	COG2357	RelA SpoT domain protein
DS830_RS07800	COG0352	thiamine-phosphate diphosphorylase activity
DS830_RS07805	COG0351	phosphomethylpyrimidine kinase
DS830_RS07810	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DS830_RS07815	COG0402	S-adenosylhomocysteine deaminase activity
DS830_RS07830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DS830_RS07835	COG0556	nucleotide-excision repair
DS830_RS07870	COG3711	transcriptional antiterminator
DS830_RS07875	COG1263	PTS System
DS830_RS07875	COG2190	(PTS) system
DS830_RS07875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS07880	COG0363	glucosamine-6-phosphate deaminase activity
DS830_RS07890	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS07890	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS07895	COG3715	PTS system
DS830_RS07900	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS07910	COG3711	transcriptional antiterminator
DS830_RS07915	COG3711	transcriptional antiterminator
DS830_RS07930	COG0583	DNA-binding transcription factor activity
DS830_RS07940	COG2030	dehydratase
DS830_RS07950	COG1072	(Pantothenic acid kinase))
DS830_RS07955	COG4684	Psort location CytoplasmicMembrane, score
DS830_RS07960	COG1940	carbohydrate kinase activity
DS830_RS07970	COG2195	Cleaves the N-terminal amino acid of tripeptides
DS830_RS08010	COG0861	Integral membrane protein TerC family
DS830_RS08020	COG0095	Lipoate-protein ligase
DS830_RS08030	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS830_RS08040	COG2188	Transcriptional regulator
DS830_RS08045	COG2723	6-phospho-beta-galactosidase activity
DS830_RS08050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS08065	COG2723	6-phospho-beta-galactosidase activity
DS830_RS08070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS08075	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS08080	COG1447	Phosphotransferase system cellobiose-specific component IIA
DS830_RS08095	COG1914	H( )-stimulated, divalent metal cation uptake system
DS830_RS08120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DS830_RS08135	COG0328	RNA-DNA hybrid ribonuclease activity
DS830_RS08140	COG2340	Cysteine-rich secretory protein family
DS830_RS08150	COG1181	Belongs to the D-alanine--D-alanine ligase family
DS830_RS08155	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DS830_RS08175	COG2365	Tyrosine phosphatase family
DS830_RS08180	COG1216	Glycosyl transferase, family 2
DS830_RS08180	COG1442	glycosyl transferase family 8
DS830_RS08190	COG4166	transmembrane transport
DS830_RS08210	COG0546	phosphoglycolate phosphatase activity
DS830_RS08235	COG1253	flavin adenine dinucleotide binding
DS830_RS08240	COG1705	Flagellar rod assembly protein muramidase FlgJ
DS830_RS08245	COG2188	Transcriptional regulator
DS830_RS08250	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
DS830_RS08260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DS830_RS08265	COG3037	sugar-specific permease SgaT UlaA
DS830_RS08280	COG1349	DNA-binding transcription factor activity
DS830_RS08285	COG1744	ABC transporter substrate-binding protein PnrA-like
DS830_RS08290	COG3845	ABC transporter
DS830_RS08295	COG4603	Belongs to the binding-protein-dependent transport system permease family
DS830_RS08300	COG1079	Belongs to the binding-protein-dependent transport system permease family
DS830_RS08305	COG2365	Tyrosine phosphatase family
DS830_RS08310	COG0589	response to stress
DS830_RS08320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DS830_RS08350	COG3590	peptidase
DS830_RS08355	COG2723	6-phospho-beta-galactosidase activity
DS830_RS08360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DS830_RS08365	COG1609	Transcriptional regulator
DS830_RS08375	COG0235	Class ii aldolase
DS830_RS08380	COG2160	L-arabinose isomerase activity
DS830_RS08385	COG3940	Belongs to the glycosyl hydrolase 43 family
DS830_RS08415	COG3775	system Galactitol-specific IIC component
DS830_RS08425	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS830_RS08435	COG1070	Carbohydrate kinase
DS830_RS08440	COG3623	hexulose-6-phosphate isomerase
DS830_RS08445	COG0235	Class ii aldolase
DS830_RS08460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DS830_RS08465	COG2050	protein possibly involved in aromatic compounds catabolism
DS830_RS08470	COG0028	Belongs to the TPP enzyme family
DS830_RS08485	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DS830_RS08490	COG1131	(ABC) transporter
DS830_RS08515	COG2017	converts alpha-aldose to the beta-anomer
DS830_RS08520	COG0735	belongs to the Fur family
DS830_RS08530	COG1121	(ABC) transporter
DS830_RS08535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DS830_RS08580	COG1063	alcohol dehydrogenase
DS830_RS08585	COG1028	Short-chain dehydrogenase reductase Sdr
DS830_RS08600	COG0789	Transcriptional regulator
DS830_RS08605	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DS830_RS08610	COG0436	Aminotransferase
DS830_RS08615	COG0531	amino acid
DS830_RS08645	COG3715	PTS system
DS830_RS08650	COG3716	PTS system mannose fructose sorbose family IID component
DS830_RS08655	COG3394	polysaccharide catabolic process
DS830_RS08660	COG1136	(ABC) transporter
DS830_RS08665	COG0577	efflux transmembrane transporter activity
DS830_RS08675	COG1846	Transcriptional regulator
DS830_RS08680	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
DS830_RS08685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DS830_RS08690	COG0516	GMP reductase activity
DS830_RS08690	COG0517	IMP dehydrogenase activity
DS830_RS08700	COG0656	L-ascorbic acid biosynthetic process
DS830_RS08710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DS830_RS08715	COG0710	3-dehydroquinate dehydratase activity
DS830_RS08725	COG1263	PTS System
DS830_RS08725	COG2190	(PTS) system
DS830_RS08725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DS830_RS08740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DS830_RS08820	COG1285	pathogenesis
DS830_RS08825	COG0006	proline dipeptidase activity