locus-tag	class	description
B2B01_RS00005	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
B2B01_RS00010	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
B2B01_RS00015	ENOG4107QJE	Chromosome Partitioning Protein
B2B01_RS00020	ENOG4105FA0	parb-like partition protein
B2B01_RS00025	ENOG4105HDK	L-asparaginase
B2B01_RS00045	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B2B01_RS00055	ENOG410683Z	Preprotein translocase SecE subunit
B2B01_RS00065	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
B2B01_RS00070	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
B2B01_RS00075	ENOG4108VZM	50s ribosomal protein L10
B2B01_RS00080	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
B2B01_RS00085	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2B01_RS00090	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2B01_RS00120	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
B2B01_RS00125	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
B2B01_RS00130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
B2B01_RS00135	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
B2B01_RS00140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
B2B01_RS00145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
B2B01_RS00150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
B2B01_RS00155	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
B2B01_RS00160	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
B2B01_RS00165	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
B2B01_RS00170	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
B2B01_RS00175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
B2B01_RS00180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
B2B01_RS00185	ENOG41084PQ	50s ribosomal protein l29
B2B01_RS00190	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
B2B01_RS00200	ENOG4105ERH	Fumarylacetoacetate hydrolase
B2B01_RS00220	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
B2B01_RS00240	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
B2B01_RS00245	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
B2B01_RS00250	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
B2B01_RS00255	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
B2B01_RS00260	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
B2B01_RS00265	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
B2B01_RS00270	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
B2B01_RS00275	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
B2B01_RS00280	ENOG4105VPB	50S ribosomal protein L30
B2B01_RS00285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
B2B01_RS00290	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
B2B01_RS00295	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
B2B01_RS00305	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
B2B01_RS00310	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
B2B01_RS00315	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
B2B01_RS00320	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
B2B01_RS00325	ENOG4108ZT0	50S ribosomal protein l17
B2B01_RS00335	ENOG4105VF7	tolerance protein
B2B01_RS00340	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
B2B01_RS00345	ENOG4105D52	delta-aminolevulinic acid dehydratase
B2B01_RS00350	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
B2B01_RS00355	ENOG4106RE7	Cytochrome
B2B01_RS00360	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
B2B01_RS00365	ENOG4105CRE	cytochrome C
B2B01_RS00370	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
B2B01_RS00380	ENOG4105XQ6	frataxin-like protein
B2B01_RS00385	ENOG4108JQC	penicillin-binding protein 1A
B2B01_RS00390	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
B2B01_RS00395	ENOG4105D49	3-dehydroquinate synthase
B2B01_RS00400	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
B2B01_RS00415	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
B2B01_RS00420	ENOG4107RDB	Major Facilitator
B2B01_RS00425	ENOG4108UUM	single-stranded DNA-binding protein
B2B01_RS00455	ENOG410838F	Glycosyl transferase family 2
B2B01_RS00485	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
B2B01_RS00495	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
B2B01_RS00505	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
B2B01_RS00510	ENOG4105J5G	Transferase hexapeptide repeat containing protein
B2B01_RS00520	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2B01_RS00525	ENOG4105DHQ	Histidine kinase
B2B01_RS00530	ENOG4105C4Y	ABC transporter
B2B01_RS00535	ENOG4107Z33	ABC transporter, permease
B2B01_RS00540	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS00550	ENOG4107QP3	malate synthase g
B2B01_RS00560	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
B2B01_RS00565	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2B01_RS00575	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B2B01_RS00600	ENOG4105C9M	aspartyl-trna synthetase
B2B01_RS00605	ENOG4105X23	Endonuclease Exonuclease phosphatase
B2B01_RS00610	ENOG4105DZQ	phospholipase D Transphosphatidylase
B2B01_RS00630	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS00640	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
B2B01_RS00645	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
B2B01_RS00650	ENOG4105D16	lipopolysaccharide heptosyltransferase i
B2B01_RS00655	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
B2B01_RS00665	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
B2B01_RS00680	ENOG4105DHJ	ABC, transporter
B2B01_RS00700	ENOG4105DZ1	carboxypeptidase
B2B01_RS00705	ENOG4105F0I	Aminotransferase
B2B01_RS00710	ENOG4108Z43	UPF0250 protein
B2B01_RS00715	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
B2B01_RS00720	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
B2B01_RS00725	ENOG4108WBT	adenosyltransferase
B2B01_RS00735	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
B2B01_RS00740	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
B2B01_RS00750	ENOG4105CKI	cobalamin synthesis protein
B2B01_RS00755	ENOG4105MYN	Zinc uptake regulation protein
B2B01_RS00760	ENOG4105DIK	(ABC) transporter
B2B01_RS00765	ENOG4105CC5	ABC transporter
B2B01_RS00770	ENOG4105DSE	periplasmic solute binding protein
B2B01_RS00785	ENOG4105UGU	tonB-dependent Receptor
B2B01_RS00790	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2B01_RS00800	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
B2B01_RS00805	ENOG4105D1S	lipid A biosynthesis
B2B01_RS00815	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
B2B01_RS00835	ENOG41086DT	Membrane protein of unknown function
B2B01_RS00840	ENOG4105SYT	Methylenetetrahydrofolate reductase
B2B01_RS00865	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
B2B01_RS00870	ENOG4107SC1	transglycosylase
B2B01_RS00875	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
B2B01_RS00885	ENOG4105C1J	atp-dependent rna helicase
B2B01_RS00890	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
B2B01_RS00895	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
B2B01_RS00925	ENOG4105CSR	polyphosphate kinase 2
B2B01_RS00935	ENOG4105DZS	Phenylacetate-CoA ligase
B2B01_RS00940	ENOG4108IV0	ABC, transporter
B2B01_RS00960	ENOG4105C0Z	ABC transporter
B2B01_RS00995	ENOG4105DFA	alanine racemase domain protein
B2B01_RS01000	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2B01_RS01005	ENOG4107QXX	ABC transporter
B2B01_RS01015	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
B2B01_RS01020	ENOG4105C79	DNA protecting protein DprA
B2B01_RS01025	ENOG4105WH1	Two component transcriptional regulator luxr family
B2B01_RS01030	ENOG4105F7P	transcriptional regulator AsnC family
B2B01_RS01040	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
B2B01_RS01045	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
B2B01_RS01055	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
B2B01_RS01060	ENOG4108URH	decarboxylase
B2B01_RS01065	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
B2B01_RS01070	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
B2B01_RS01105	ENOG4105F95	Monooxygenase
B2B01_RS01110	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
B2B01_RS01120	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
B2B01_RS01125	ENOG4105MP9	class II Aldolase
B2B01_RS01155	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
B2B01_RS01160	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS01165	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2B01_RS01170	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
B2B01_RS01185	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2B01_RS01190	ENOG4105C1A	potassium transporter peripheral membrane
B2B01_RS01195	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
B2B01_RS01200	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
B2B01_RS01205	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
B2B01_RS01210	ENOG41081UC	Inherit from COG: Competence protein
B2B01_RS01225	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
B2B01_RS01230	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
B2B01_RS01235	ENOG4105VW4	glutaredoxin 3
B2B01_RS01245	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
B2B01_RS01250	ENOG41063SB	peptidase
B2B01_RS01255	ENOG4105CN1	protease
B2B01_RS01260	ENOG4105D06	uba thif-type nad fad binding protein
B2B01_RS01265	ENOG4107YCY	Transcriptional regulator
B2B01_RS01275	ENOG4105DU1	integral membrane protein, terc
B2B01_RS01280	ENOG41063Z6	transcriptional regulator, lysR family
B2B01_RS01285	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
B2B01_RS01290	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B2B01_RS01310	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
B2B01_RS01315	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
B2B01_RS01320	ENOG4105K46	50S ribosomal protein l27
B2B01_RS01325	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
B2B01_RS01330	ENOG4105EAH	synthase
B2B01_RS01350	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
B2B01_RS01385	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B2B01_RS01415	ENOG4105CK2	sodium dicarboxylate symporter
B2B01_RS01455	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS01465	ENOG4105RQF	LysR family Transcriptional regulator
B2B01_RS01475	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS01480	ENOG4105C0Z	ABC transporter
B2B01_RS01485	ENOG4108IV0	ABC, transporter
B2B01_RS01515	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
B2B01_RS01520	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
B2B01_RS01525	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
B2B01_RS01535	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
B2B01_RS01550	ENOG4107B2H	carbonic anhydrase
B2B01_RS01560	ENOG4105F2Z	3-oxoadipate enol-lactonase
B2B01_RS01575	ENOG4107QNJ	CoA-transferase subunit B
B2B01_RS01590	ENOG4105CRW	Short chain fatty acid transporter
B2B01_RS01595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B2B01_RS01620	ENOG4105C01	Dihydroxy-acid dehydratase
B2B01_RS01630	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
B2B01_RS01635	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
B2B01_RS01645	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
B2B01_RS01650	ENOG4105GP2	5'(3')-deoxyribonucleotidase
B2B01_RS01665	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2B01_RS01670	ENOG4105CBN	LysR family transcriptional regulator
B2B01_RS01675	ENOG4105IPI	Membrane
B2B01_RS01680	ENOG4105EV8	ectoine hydroxylase
B2B01_RS01685	ENOG4107SVH	Potassium channel protein
B2B01_RS01695	ENOG4105D7Q	type ii secretion system
B2B01_RS01700	ENOG4105GVR	general secretion pathway protein D
B2B01_RS01705	ENOG4107QHF	type ii secretion system protein e
B2B01_RS01730	ENOG4108WWZ	General secretion pathway protein J
B2B01_RS01735	ENOG4105X5Z	General secretion pathway protein I
B2B01_RS01745	ENOG4108VAU	general secretion pathway protein G
B2B01_RS01770	ENOG410839U	amino acid
B2B01_RS01775	ENOG4105C85	amino acid
B2B01_RS01785	ENOG4108M8H	domain protein
B2B01_RS01790	ENOG4107SDU	Methyl-accepting chemotaxis
B2B01_RS01795	ENOG4105QNF	Outer membrane lipoprotein
B2B01_RS01805	ENOG4105C7W	Xanthine dehydrogenase
B2B01_RS01810	ENOG4108Z9W	Outer membrane porin
B2B01_RS01815	ENOG41090ED	Protein with unknown function (DUF469)
B2B01_RS01865	ENOG4108R1E	Serine threonine protein phosphatase 1
B2B01_RS01895	ENOG4105CH6	catalase
B2B01_RS01900	ENOG4105C2W	permease
B2B01_RS01905	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
B2B01_RS01910	ENOG4108TGY	Glutathione S-transferase
B2B01_RS01925	ENOG4105CRE	cytochrome C
B2B01_RS01930	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2B01_RS01935	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B2B01_RS01945	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
B2B01_RS01965	ENOG4107QWB	Ornithine cyclodeaminase
B2B01_RS01975	ENOG4107S4Y	M20 DapE family protein YgeY
B2B01_RS01995	ENOG4105CYW	agmatinase
B2B01_RS02025	ENOG4105DIJ	Phosphoethanolamine transferase
B2B01_RS02030	ENOG4105DIJ	Phosphoethanolamine transferase
B2B01_RS02045	ENOG4105C72	UPF0176 protein
B2B01_RS02050	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
B2B01_RS02075	ENOG4105DHP	deoxycytidine triphosphate deaminase
B2B01_RS02090	ENOG4105CXN	decarboxylase
B2B01_RS02095	ENOG4105CBX	hi0933 family
B2B01_RS02100	ENOG4105ETE	Transcriptional regulator (LacI family
B2B01_RS02105	ENOG41083Z3	extracellular ligand-binding receptor
B2B01_RS02110	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS02115	ENOG4105C0Z	ABC transporter
B2B01_RS02120	ENOG4108IV0	ABC, transporter
B2B01_RS02130	ENOG4105CHR	reductase
B2B01_RS02135	ENOG4105DCT	glycerol dehydrogenase
B2B01_RS02145	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
B2B01_RS02150	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
B2B01_RS02155	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
B2B01_RS02185	ENOG4108JQ6	ABC transporter
B2B01_RS02210	ENOG4105C26	Dehydrogenase
B2B01_RS02215	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B2B01_RS02220	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2B01_RS02230	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
B2B01_RS02240	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
B2B01_RS02245	ENOG4107UKG	Glycosyl transferase, family 4
B2B01_RS02250	ENOG4107QQG	Dehydrogenase
B2B01_RS02265	ENOG4105CG5	Glycosyl transferase (Group 1
B2B01_RS02275	ENOG4107XU6	Glycosyl transferase (Group 1
B2B01_RS02280	ENOG4105CPK	Glycosyl transferase (Group 1
B2B01_RS02290	ENOG4107QP8	phosphohexose isomerase
B2B01_RS02295	ENOG4107QKV	phosphomannomutase
B2B01_RS02305	ENOG4105CQB	FAD linked oxidase domain protein
B2B01_RS02310	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2B01_RS02315	ENOG4105BZU	Histidine kinase
B2B01_RS02320	ENOG4107YCY	Transcriptional regulator
B2B01_RS02325	ENOG4105E0M	Sulfatase
B2B01_RS02335	ENOG4105F1J	Homogentisate 1,2-dioxygenase
B2B01_RS02350	ENOG4107SCK	Monooxygenase
B2B01_RS02360	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
B2B01_RS02365	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
B2B01_RS02370	ENOG41081V9	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
B2B01_RS02375	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
B2B01_RS02385	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
B2B01_RS02390	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
B2B01_RS02395	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
B2B01_RS02405	ENOG4105C3G	gtp-binding protein
B2B01_RS02420	ENOG4105DZR	Type I site-specific deoxyribonuclease
B2B01_RS02430	ENOG4105EKX	Restriction modification system DNA (Specificity
B2B01_RS02435	ENOG4105CVR	type I restriction-modification system
B2B01_RS02505	ENOG4105DKK	Benzoate
B2B01_RS02510	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
B2B01_RS02515	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
B2B01_RS02520	ENOG4106H78	methyltransferase
B2B01_RS02550	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
B2B01_RS02555	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
B2B01_RS02560	ENOG4107YIM	Involved in the transcription termination process (By similarity)
B2B01_RS02565	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
B2B01_RS02570	ENOG4108ZAI	phosphatidylglycerophosphatase a
B2B01_RS02580	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
B2B01_RS02585	ENOG4105CEP	NADH dehydrogenase
B2B01_RS02590	ENOG41080IJ	Diacylglycerol kinase
B2B01_RS02595	ENOG4107S2Z	UPF0761 membrane protein
B2B01_RS02600	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
B2B01_RS02605	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
B2B01_RS02620	ENOG4105D9P	serine threonine protein kinase
B2B01_RS02640	ENOG4105DXI	Major Facilitator superfamily
B2B01_RS02655	ENOG4105K89	arsenate reductase
B2B01_RS02660	ENOG4105CAU	Arsenical resistance protein, ArsH
B2B01_RS02675	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B2B01_RS02715	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
B2B01_RS02720	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
B2B01_RS02730	ENOG4105CSH	Transporter
B2B01_RS02760	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
B2B01_RS02775	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
B2B01_RS02780	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
B2B01_RS02790	ENOG4105ERH	Fumarylacetoacetate hydrolase
B2B01_RS02825	ENOG4105CHR	reductase
B2B01_RS02830	ENOG4105CHR	reductase
B2B01_RS02835	ENOG4105CR4	methylisocitrate lyase
B2B01_RS02840	ENOG4105DRR	Transcriptional regulator, GntR family
B2B01_RS02845	ENOG4107QM5	aconitate hydratase
B2B01_RS02850	ENOG4105CD3	dihydroorotase
B2B01_RS02855	ENOG4108UAU	isochorismatase
B2B01_RS02860	ENOG4105CKI	cobalamin synthesis protein
B2B01_RS02920	ENOG4105CMQ	Chloride channel
B2B01_RS02930	ENOG4105CHR	reductase
B2B01_RS02940	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS02945	ENOG4105E2Y	ABC, transporter
B2B01_RS02960	ENOG4105D9U	N-acetyltransferase
B2B01_RS02965	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
B2B01_RS02990	ENOG4105ERH	Fumarylacetoacetate hydrolase
B2B01_RS03035	ENOG4105CNV	Aldolase
B2B01_RS03055	ENOG4105EXG	Transcriptional regulator
B2B01_RS03065	ENOG4105C1J	atp-dependent rna helicase
B2B01_RS03075	ENOG4105C5I	Dehydrogenase
B2B01_RS03080	ENOG4105RQF	LysR family Transcriptional regulator
B2B01_RS03100	ENOG4105E89	ABC transporter
B2B01_RS03105	ENOG4105CDA	abc transporter atp-binding protein
B2B01_RS03110	ENOG4105E5Q	amino acid AbC transporter
B2B01_RS03115	ENOG4105E5Q	amino acid AbC transporter
B2B01_RS03120	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B2B01_RS03145	ENOG4105F7P	transcriptional regulator AsnC family
B2B01_RS03150	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
B2B01_RS03155	ENOG4105CPC	Aldo Keto reductase
B2B01_RS03165	ENOG4105KZX	Pterin carbinolamine dehydratase
B2B01_RS03175	ENOG4108S0S	Nucleotidyl transferase
B2B01_RS03180	ENOG4105EHM	Aminoglycoside phosphotransferase
B2B01_RS03185	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
B2B01_RS03190	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
B2B01_RS03195	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
B2B01_RS03200	ENOG4105BZW	Glycerate kinase
B2B01_RS03205	ENOG4105CA9	Pyruvate kinase
B2B01_RS03215	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
B2B01_RS03225	ENOG41079YP	Citrate utilization protein b
B2B01_RS03235	ENOG4105EF7	Transcriptional regulator
B2B01_RS03245	ENOG4105E9Q	Acyl-transferase
B2B01_RS03250	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
B2B01_RS03255	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
B2B01_RS03260	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
B2B01_RS03265	ENOG4106YT9	Enoyl-CoA hydratase
B2B01_RS03275	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS03275	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS03280	ENOG4108M9J	MaoC like domain protein
B2B01_RS03305	ENOG4105D3W	isochorismatase
B2B01_RS03310	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B2B01_RS03315	ENOG4105DJ0	Poly(A) Polymerase
B2B01_RS03325	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
B2B01_RS03330	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
B2B01_RS03335	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
B2B01_RS03340	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
B2B01_RS03345	ENOG4105DQR	SNARE associated Golgi
B2B01_RS03355	ENOG4105C7K	acetolactate synthase
B2B01_RS03360	ENOG4105DWT	malate dehydrogenase (quinone)
B2B01_RS03375	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
B2B01_RS03380	ENOG4105K8N	protein family UPF0079, ATPase
B2B01_RS03385	ENOG4105C9Q	fumarate hydratase class II
B2B01_RS03420	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
B2B01_RS03445	ENOG4105CYM	Glutathione S-transferase
B2B01_RS03450	ENOG4105CM2	brancheD-chain amino acid aminotransferase
B2B01_RS03460	ENOG4108MEJ	flavin reductase domain protein
B2B01_RS03470	ENOG4105KCK	Peptidoglycan-associated lipoprotein
B2B01_RS03485	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS03495	ENOG4108JJ7	ABC transporter
B2B01_RS03505	ENOG4108IQI	permease
B2B01_RS03515	ENOG4105BZU	Histidine kinase
B2B01_RS03535	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B2B01_RS03545	ENOG4107RN3	metallophosphoesterase
B2B01_RS03565	ENOG4105CY2	Citrate transporter
B2B01_RS03570	ENOG4108TGY	Glutathione S-transferase
B2B01_RS03575	ENOG4105EA8	2-Nitropropane dioxygenase
B2B01_RS03580	ENOG4105EGI	Transcriptional regulator
B2B01_RS03585	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
B2B01_RS03590	ENOG4107QSI	ABC, transporter
B2B01_RS03630	ENOG4108UYB	regulatoR
B2B01_RS03635	ENOG4105E2S	oxidase) subunit II
B2B01_RS03640	ENOG4105BZ9	Cytochrome C oxidase, subunit I
B2B01_RS03645	ENOG4105CCU	oxidase (Subunit III)
B2B01_RS03650	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
B2B01_RS03660	ENOG4107SDU	Methyl-accepting chemotaxis
B2B01_RS03665	ENOG4108K5P	(LipO)protein
B2B01_RS03670	ENOG4108VPT	UPF0234 protein
B2B01_RS03690	ENOG4105E6M	Sulphatase-modifying factor protein
B2B01_RS03700	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B2B01_RS03750	ENOG4105CHR	reductase
B2B01_RS03755	ENOG4107AQZ	Membrane
B2B01_RS03770	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
B2B01_RS03780	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
B2B01_RS03785	ENOG4108IEG	Formate dehydrogenase Alpha subunit
B2B01_RS03790	ENOG4107QIZ	NADH dehydrogenase
B2B01_RS03805	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B2B01_RS03815	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
B2B01_RS03820	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B2B01_RS03825	ENOG4108ZAF	Molybdopterin
B2B01_RS03830	ENOG4105M00	molybdopterin converting factor, subunit 1
B2B01_RS03835	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
B2B01_RS03855	ENOG4108TZV	Membrane
B2B01_RS03860	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
B2B01_RS03910	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
B2B01_RS03915	ENOG4105C9A	Phoh family
B2B01_RS03920	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
B2B01_RS03925	ENOG4108JU5	Magnesium and cobalt efflux protein
B2B01_RS03930	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
B2B01_RS03935	ENOG4108FN7	Aldo keto reductase
B2B01_RS03955	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B2B01_RS03960	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
B2B01_RS03965	ENOG4105VIE	preprotein translocase, subunit YajC
B2B01_RS03970	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
B2B01_RS03975	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
B2B01_RS03980	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
B2B01_RS03985	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
B2B01_RS03990	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
B2B01_RS04020	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
B2B01_RS04035	ENOG4105CHM	Aminotransferase
B2B01_RS04045	ENOG4105C6K	Malic enzyme
B2B01_RS04060	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
B2B01_RS04065	ENOG4105CV1	Transketolase (EC 2.2.1.1)
B2B01_RS04070	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
B2B01_RS04075	ENOG4105BZA	Phosphoglycerate kinase
B2B01_RS04085	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
B2B01_RS04090	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
B2B01_RS04105	ENOG4108SHQ	Glutathione S-transferase
B2B01_RS04135	ENOG4105CJ3	phosphate transporter
B2B01_RS04140	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
B2B01_RS04150	ENOG4105DR5	peptidase
B2B01_RS04160	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
B2B01_RS04170	ENOG410631K	Membrane
B2B01_RS04185	ENOG4108R6G	acetyltransferase
B2B01_RS04190	ENOG4105CK2	sodium dicarboxylate symporter
B2B01_RS04200	ENOG4105C8V	SAICAR synthetase
B2B01_RS04205	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
B2B01_RS04210	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
B2B01_RS04215	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B2B01_RS04220	ENOG4108FUF	Transcriptional regulator, IclR family
B2B01_RS04225	ENOG4105CYW	agmatinase
B2B01_RS04230	ENOG4105EAB	amino acid AbC transporter
B2B01_RS04235	ENOG4105E5Q	amino acid AbC transporter
B2B01_RS04240	ENOG4105CDA	abc transporter atp-binding protein
B2B01_RS04255	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS04260	ENOG4105C7K	acetolactate synthase
B2B01_RS04265	ENOG4105ETT	transcriptional Regulator, LysR family
B2B01_RS04270	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2B01_RS04275	ENOG4108Z66	YbaK ebsC protein
B2B01_RS04290	ENOG41061WM	D-Alanyl-D-Alanine
B2B01_RS04310	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
B2B01_RS04320	ENOG4107QMP	dna polymerase iii subunits gamma and tau
B2B01_RS04325	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
B2B01_RS04330	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
B2B01_RS04340	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
B2B01_RS04345	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
B2B01_RS04350	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
B2B01_RS04355	ENOG4105CVJ	phosphoglycerate mutase
B2B01_RS04360	ENOG4105DUM	transcriptional regulator, lysR family
B2B01_RS04365	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS04385	ENOG4105C2W	permease
B2B01_RS04390	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
B2B01_RS04395	ENOG4105HBR	Rna-binding protein
B2B01_RS04400	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
B2B01_RS04405	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
B2B01_RS04410	ENOG4105EEI	dihydropteroate synthase
B2B01_RS04415	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
B2B01_RS04425	ENOG4105C9X	ppx gppa phosphatase
B2B01_RS04435	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS04440	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS04445	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
B2B01_RS04450	ENOG4105C8U	phosphate abc transporter
B2B01_RS04455	ENOG4105E2Z	phosphate ABC transporter (Permease
B2B01_RS04460	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS04485	ENOG4105FDP	GntR family transcriptional regulator
B2B01_RS04490	ENOG4105CP9	extracellular ligand-binding receptor
B2B01_RS04495	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS04500	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2B01_RS04505	ENOG4105C0Z	ABC transporter
B2B01_RS04510	ENOG4108IV0	ABC, transporter
B2B01_RS04515	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B2B01_RS04520	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B2B01_RS04540	ENOG4107EFR	Flavocytochrome c
B2B01_RS04560	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2B01_RS04580	ENOG4105CH2	amidohydrolase
B2B01_RS04590	ENOG4105E1V	na solute symporter
B2B01_RS04605	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
B2B01_RS04630	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
B2B01_RS04640	ENOG4108MUZ	hydrolase
B2B01_RS04650	ENOG4105CEY	Amp-dependent synthetase and ligase
B2B01_RS04655	ENOG4108IV0	ABC, transporter
B2B01_RS04665	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2B01_RS04670	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS04705	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B2B01_RS04710	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B2B01_RS04730	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS04755	ENOG4108J59	Extracellular solute-binding protein, family 5
B2B01_RS04765	ENOG4105BZU	Histidine kinase
B2B01_RS04785	ENOG4105EEQ	Na H antiporter
B2B01_RS04800	ENOG4105J12	Multidrug resistance protein mdtN
B2B01_RS04815	ENOG4105CI2	imidazolone-5-propionate hydrolase
B2B01_RS04830	ENOG4107QM5	aconitate hydratase
B2B01_RS04835	ENOG4105FQ6	thiopurine methyltransferase
B2B01_RS04845	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS04855	ENOG4108KTQ	Methyltransferase
B2B01_RS04865	ENOG4105CBS	Chea signal transduction histidine kinase
B2B01_RS04870	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
B2B01_RS04880	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
B2B01_RS04885	ENOG4108J59	Extracellular solute-binding protein, family 5
B2B01_RS04905	ENOG4108R4R	Iron-regulated virulence regulatory protein
B2B01_RS04920	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2B01_RS04930	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
B2B01_RS04955	ENOG4108Z9W	Outer membrane porin
B2B01_RS04960	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B2B01_RS04965	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2B01_RS04970	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B2B01_RS04975	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2B01_RS04990	ENOG4108IEH	NADH dehydrogenase subunit g
B2B01_RS04995	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
B2B01_RS05000	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2B01_RS05005	ENOG4105DF2	NADH dehydrogenase subunit j
B2B01_RS05010	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2B01_RS05020	ENOG4105C8S	subunit m
B2B01_RS05025	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
B2B01_RS05045	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
B2B01_RS05050	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
B2B01_RS05055	ENOG4108JA2	transcriptioN-repair coupling factor
B2B01_RS05060	ENOG4105EAC	phosphoserine phosphatase
B2B01_RS05065	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
B2B01_RS05070	ENOG4105D3R	alkyl hydroperoxide reductase
B2B01_RS05075	ENOG4105E0F	Histidine kinase
B2B01_RS05085	ENOG41072GX	Peptidase M22 Glycoprotease
B2B01_RS05090	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
B2B01_RS05095	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
B2B01_RS05100	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
B2B01_RS05110	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
B2B01_RS05115	ENOG4107TF3	peptidylprolyl cis-trans isomerase
B2B01_RS05125	ENOG4107835	probably involved in intracellular septation (By similarity)
B2B01_RS05130	ENOG4105E0X	reductase
B2B01_RS05135	ENOG4108JJB	ABC transporter
B2B01_RS05140	ENOG4107QCX	Transporter
B2B01_RS05145	ENOG4107ZYJ	bioY protein
B2B01_RS05160	ENOG4105C0Z	ABC transporter
B2B01_RS05165	ENOG4108IV0	ABC, transporter
B2B01_RS05170	ENOG4105HSS	phospholipase C
B2B01_RS05175	ENOG4105CM2	brancheD-chain amino acid aminotransferase
B2B01_RS05185	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS05195	ENOG4108IV0	ABC, transporter
B2B01_RS05200	ENOG4105C0Z	ABC transporter
B2B01_RS05205	ENOG4105CSM	endonuclease III
B2B01_RS05210	ENOG4108R3D	Electron transport complex
B2B01_RS05220	ENOG4105DP0	ferredoxin-NADP reductase
B2B01_RS05225	ENOG4108Z4U	Ferredoxin
B2B01_RS05230	ENOG4107RH7	Nicotinate phosphoribosyltransferase
B2B01_RS05235	ENOG4105M4H	endoribonuclease L-psp
B2B01_RS05245	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
B2B01_RS05250	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B2B01_RS05265	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
B2B01_RS05270	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
B2B01_RS05275	ENOG41061N2	exported protein
B2B01_RS05290	ENOG4105C03	ribonuclease
B2B01_RS05295	ENOG4105EI2	Pseudouridine synthase
B2B01_RS05305	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
B2B01_RS05310	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
B2B01_RS05315	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
B2B01_RS05325	ENOG4108UHJ	MAF-like protein
B2B01_RS05330	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
B2B01_RS05335	ENOG4105VGS	50s ribosomal protein l32
B2B01_RS05345	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
B2B01_RS05350	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
B2B01_RS05355	ENOG4105CHR	reductase
B2B01_RS05360	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
B2B01_RS05365	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
B2B01_RS05370	ENOG4105EMN	RNA polymerase sigma factor
B2B01_RS05385	ENOG4105C0H	protease
B2B01_RS05390	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
B2B01_RS05395	ENOG4105C3F	Signal peptidase i
B2B01_RS05400	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
B2B01_RS05405	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
B2B01_RS05410	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
B2B01_RS05430	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
B2B01_RS05440	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
B2B01_RS05450	ENOG4105C26	Dehydrogenase
B2B01_RS05455	ENOG4107R11	Transcriptional regulator
B2B01_RS05465	ENOG4105K4H	Nlp p60 protein
B2B01_RS05470	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2B01_RS05475	ENOG4108ZJF	Glcg protein
B2B01_RS05485	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2B01_RS05490	ENOG4105C5W	Aldolase
B2B01_RS05500	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
B2B01_RS05525	ENOG4105D44	asparaginase
B2B01_RS05530	ENOG4108JQ6	ABC transporter
B2B01_RS05535	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS05540	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS05545	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS05565	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
B2B01_RS05570	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
B2B01_RS05585	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
B2B01_RS05590	ENOG4108Z0R	Transferase
B2B01_RS05595	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
B2B01_RS05610	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B2B01_RS05620	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
B2B01_RS05625	ENOG4108YXA	Membrane
B2B01_RS05630	ENOG4105BZN	citrate synthase
B2B01_RS05635	ENOG4105CR4	methylisocitrate lyase
B2B01_RS05640	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
B2B01_RS05645	ENOG4105FDP	GntR family transcriptional regulator
B2B01_RS05650	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
B2B01_RS05655	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
B2B01_RS05665	ENOG4105E33	succinate dehydrogenase
B2B01_RS05670	ENOG41060IS	Flavinator of succinate dehydrogenase
B2B01_RS05675	ENOG4105BZN	citrate synthase
B2B01_RS05680	ENOG4105BZU	Histidine kinase
B2B01_RS05690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS05700	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
B2B01_RS05710	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B2B01_RS05720	ENOG4107E2E	PKHD-type hydroxylase
B2B01_RS05725	ENOG4108ESX	Receptor
B2B01_RS05740	ENOG4105C6K	Malic enzyme
B2B01_RS05745	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
B2B01_RS05750	ENOG4105EPD	Oligopeptide transporter, Opt family
B2B01_RS05755	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
B2B01_RS05760	ENOG4105C7S	Dehydrogenase
B2B01_RS05765	ENOG4107QN2	dihydrolipoyl dehydrogenase
B2B01_RS05770	ENOG4105D6Z	AFG1 family ATPase
B2B01_RS05775	ENOG4108SF5	RNA Polymerase
B2B01_RS05780	ENOG4108S3W	Anti-feci sigma factor, fecr
B2B01_RS05785	ENOG4105E0K	tonB-dependent siderophore receptor
B2B01_RS05810	ENOG4105DVT	helicase
B2B01_RS05815	ENOG4105BZM	domain protein
B2B01_RS05830	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS05835	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2B01_RS05840	ENOG4105C34	Pseudouridine synthase
B2B01_RS05845	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
B2B01_RS05850	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
B2B01_RS05855	ENOG4105CHR	reductase
B2B01_RS05860	ENOG4108NVM	synthesis repressor PhaR
B2B01_RS05875	ENOG4105EKT	)-iron permease
B2B01_RS05885	ENOG4105JAB	phenazine biosynthesis protein, phzf family
B2B01_RS05900	ENOG4105VDW	Csbd family
B2B01_RS05915	ENOG4105BZ1	(ABC) transporter
B2B01_RS05925	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
B2B01_RS05930	ENOG4105ED9	Protein of unknown function (DUF455)
B2B01_RS05935	ENOG4105CVE	Lytic murein transglycosylase
B2B01_RS05950	ENOG4108KF1	Membrane
B2B01_RS05960	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
B2B01_RS05965	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
B2B01_RS05980	ENOG4108IUS	Transketolase
B2B01_RS05985	ENOG4108HHA	Transketolase
B2B01_RS06005	ENOG4105FAW	cDP-glucose 4,6-dehydratase
B2B01_RS06010	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
B2B01_RS06045	ENOG4105ERH	Fumarylacetoacetate hydrolase
B2B01_RS06050	ENOG4105C26	Dehydrogenase
B2B01_RS06055	ENOG4105KME	endoribonuclease L-psp
B2B01_RS06060	ENOG4105KME	endoribonuclease L-psp
B2B01_RS06070	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS06075	ENOG4108IV0	ABC, transporter
B2B01_RS06080	ENOG4105C0Z	ABC transporter
B2B01_RS06115	ENOG4105F27	Major Facilitator
B2B01_RS06120	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2B01_RS06125	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
B2B01_RS06130	ENOG4105UYK	outer membrane protein a
B2B01_RS06135	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2B01_RS06140	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
B2B01_RS06160	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
B2B01_RS06165	ENOG4105CAT	Cytidine monophosphate kinase
B2B01_RS06170	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
B2B01_RS06185	ENOG4105CFV	Tetratricopeptide repeat protein
B2B01_RS06190	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
B2B01_RS06195	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
B2B01_RS06205	ENOG4105C6T	cysteine synthase
B2B01_RS06210	ENOG4105CVE	Lytic murein transglycosylase
B2B01_RS06215	ENOG4105DGU	Histone deacetylase
B2B01_RS06220	ENOG4105BZJ	Electron transfer flavoprotein
B2B01_RS06225	ENOG4105C10	Electron transfer flavoprotein
B2B01_RS06230	ENOG4105D0C	transport protein
B2B01_RS06235	ENOG4105CSU	acyl-Coa dehydrogenase
B2B01_RS06240	ENOG4105D3R	alkyl hydroperoxide reductase
B2B01_RS06265	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
B2B01_RS06275	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
B2B01_RS06280	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
B2B01_RS06285	ENOG4105D0M	Protease HtpX homolog
B2B01_RS06290	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
B2B01_RS06295	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
B2B01_RS06300	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
B2B01_RS06305	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
B2B01_RS06310	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
B2B01_RS06315	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
B2B01_RS06320	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
B2B01_RS06330	ENOG4108UKI	Enoyl-CoA hydratase
B2B01_RS06335	ENOG4108ZJI	phenylacetic acid degradation protein
B2B01_RS06355	ENOG4105D4P	Coproporphyrinogen iii oxidase
B2B01_RS06360	ENOG41068CG	regulatoR
B2B01_RS06365	ENOG4105C22	threonyL-tRNA synthetase
B2B01_RS06370	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
B2B01_RS06385	ENOG41080Z8	PHOSPHOCARRIER protein
B2B01_RS06390	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
B2B01_RS06395	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
B2B01_RS06400	ENOG4105CIF	Ornithine Cyclodeaminase
B2B01_RS06410	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
B2B01_RS06430	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
B2B01_RS06445	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
B2B01_RS06450	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
B2B01_RS06455	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
B2B01_RS06460	ENOG4105DTN	riboflavin biosynthesis protein ribF
B2B01_RS06465	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
B2B01_RS06485	ENOG4105C4R	Atp-dependent dna helicase
B2B01_RS06490	ENOG4105C5H	ABC transporter
B2B01_RS06495	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
B2B01_RS06500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
B2B01_RS06505	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
B2B01_RS06520	ENOG4107R08	Integrase
B2B01_RS06545	ENOG4108PNI	recT protein
B2B01_RS06550	ENOG41076J9	exonuclease VIII
B2B01_RS06655	ENOG4105CAR	Terminase, large subunit
B2B01_RS06785	ENOG4105W08	virulence gene repressor rsal
B2B01_RS06815	ENOG4105VEQ	Cold shock protein
B2B01_RS06825	ENOG4105VEQ	Cold shock protein
B2B01_RS06830	ENOG4108TEB	UPF0114 protein
B2B01_RS06835	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
B2B01_RS06840	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
B2B01_RS06845	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
B2B01_RS06850	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
B2B01_RS06860	ENOG4105DKK	Benzoate
B2B01_RS06865	ENOG4105F27	Major Facilitator
B2B01_RS06870	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
B2B01_RS06875	ENOG4105CGF	Aromatic amino acid aminotransferase
B2B01_RS06880	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
B2B01_RS06895	ENOG4105C3J	Cysteine desulfurase
B2B01_RS06900	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
B2B01_RS06905	ENOG4108Z4V	iron-sulfur cluster assembly
B2B01_RS06910	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
B2B01_RS06915	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
B2B01_RS06920	ENOG4108ZIT	Ferredoxin, 2FE-2S
B2B01_RS06925	ENOG4105WVQ	Fe-S assembly protein IscX
B2B01_RS06930	ENOG4108Z5K	methylglyoxal synthase
B2B01_RS06940	ENOG4105CRK	lysyL-tRNA synthetase
B2B01_RS06945	ENOG410904N	short-chain dehydrogenase reductase
B2B01_RS06955	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
B2B01_RS06970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
B2B01_RS06975	ENOG4105F8V	Hydrolase, tatD family
B2B01_RS06990	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
B2B01_RS06995	ENOG4108UAU	isochorismatase
B2B01_RS07010	ENOG4105RE0	Asp Glu hydantoin racemase
B2B01_RS07020	ENOG4108XHQ	(2Fe-2S)-binding domain protein
B2B01_RS07025	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
B2B01_RS07030	ENOG41079KZ	Major Facilitator Superfamily
B2B01_RS07035	ENOG4108VHT	MarR family transcriptional regulator
B2B01_RS07040	ENOG4105DUM	transcriptional regulator, lysR family
B2B01_RS07045	ENOG4105CSP	Major Facilitator Superfamily
B2B01_RS07055	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
B2B01_RS07060	ENOG4108EC8	DNA internalization-related competence protein ComEC
B2B01_RS07065	ENOG4105BZU	Histidine kinase
B2B01_RS07075	ENOG4105DB7	PHP domain protein
B2B01_RS07080	ENOG4108RRZ	Transcription elongation factor GreB
B2B01_RS07085	ENOG4108ETH	Formylglycinamide ribotide synthetase
B2B01_RS07095	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS07095	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS07130	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS07135	ENOG4108JQ7	(ABC) transporter
B2B01_RS07140	ENOG4105C3U	ABC transporter
B2B01_RS07145	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS07150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS07155	ENOG4105E1J	oxidoreductase
B2B01_RS07170	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
B2B01_RS07175	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B2B01_RS07215	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
B2B01_RS07225	ENOG4105CH5	extracellular solute-binding protein, family 7
B2B01_RS07235	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
B2B01_RS07250	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
B2B01_RS07255	ENOG4105CSH	Transporter
B2B01_RS07260	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
B2B01_RS07280	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
B2B01_RS07285	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
B2B01_RS07290	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
B2B01_RS07315	ENOG4105XYF	acetyltransferase
B2B01_RS07320	ENOG4105EUJ	GTP cyclohydrolase i
B2B01_RS07330	ENOG4105DFA	alanine racemase domain protein
B2B01_RS07335	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
B2B01_RS07340	ENOG4105CSW	GntR family transcriptional regulator
B2B01_RS07355	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
B2B01_RS07365	ENOG4108RWP	Major Facilitator Superfamily protein
B2B01_RS07370	ENOG4105WAB	arsR family transcriptional regulator
B2B01_RS07375	ENOG4108IQI	permease
B2B01_RS07380	ENOG4105F27	Major Facilitator
B2B01_RS07425	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B2B01_RS07430	ENOG4105DC8	reductase
B2B01_RS07450	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
B2B01_RS07455	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B2B01_RS07505	ENOG4105CH7	arginosuccinase
B2B01_RS07510	ENOG4105CUY	Mechanosensitive ion channel
B2B01_RS07520	ENOG4108YZA	Nitrogen regulatory protein pii
B2B01_RS07545	ENOG4105DUM	transcriptional regulator, lysR family
B2B01_RS07550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
B2B01_RS07555	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS07560	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS07565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS07570	ENOG4108JQ6	ABC transporter
B2B01_RS07575	ENOG4105N14	lysine exporter protein LysE YggA
B2B01_RS07580	ENOG4108VWS	Yaeq family
B2B01_RS07585	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
B2B01_RS07590	ENOG4105FE9	pseudouridine synthase
B2B01_RS07595	ENOG4105JQN	Transcriptional regulator
B2B01_RS07600	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2B01_RS07605	ENOG4105BZS	acriflavin resistance protein
B2B01_RS07610	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2B01_RS07635	ENOG4105DGW	oligopeptidase A
B2B01_RS07640	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
B2B01_RS07645	ENOG4108ZXC	Two component transcriptional regulator, luxr family
B2B01_RS07650	ENOG4105BZU	Histidine kinase
B2B01_RS07655	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
B2B01_RS07660	ENOG4107QSN	dihydrolipoamide acetyltransferase
B2B01_RS07665	ENOG4107QN2	dihydrolipoyl dehydrogenase
B2B01_RS07670	ENOG4106R49	Methyltransferase
B2B01_RS07680	ENOG4105I03	Flagellin
B2B01_RS07685	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2B01_RS07690	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
B2B01_RS07695	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
B2B01_RS07700	ENOG4107RD7	Flagellar Motor Protein, MotA
B2B01_RS07705	ENOG4105ER2	Ompa motb domain protein
B2B01_RS07710	ENOG4108VYJ	response regulator receiver protein
B2B01_RS07715	ENOG4105CBS	Chea signal transduction histidine kinase
B2B01_RS07720	ENOG4108V3W	Chemotaxis protein, CheW
B2B01_RS07725	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS07730	ENOG4105BZU	Histidine kinase
B2B01_RS07735	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
B2B01_RS07740	ENOG4108VYJ	response regulator receiver protein
B2B01_RS07745	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
B2B01_RS07750	ENOG4105D00	flagellar biosynthetic protein flhB
B2B01_RS07755	ENOG4105D7B	Flagellar biosynthesis protein flha
B2B01_RS07760	ENOG4105FZW	flagellar biosynthesis regulator FlhF
B2B01_RS07770	ENOG4105M9M	anti-sigma28 factor FlgM
B2B01_RS07775	ENOG4105CKS	Flagella basal body P-ring formation protein flgA
B2B01_RS07780	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
B2B01_RS07785	ENOG4108ZC9	flagellar basal-body rod protein flgc
B2B01_RS07790	ENOG4105W00	Flagellar hook capping protein
B2B01_RS07795	ENOG4105BZE	flagellar hook protein, FlgE
B2B01_RS07800	ENOG4108KPB	Flagellar basal-body rod protein FlgF
B2B01_RS07805	ENOG4105CGA	flagellar basal-body rod protein FlgG
B2B01_RS07815	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
B2B01_RS07820	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
B2B01_RS07825	ENOG4105E1Q	flagellar hook-associated protein
B2B01_RS07830	ENOG4105DTJ	flagellar hook-associated protein
B2B01_RS07835	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS07840	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS07850	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS07855	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS07860	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
B2B01_RS07865	ENOG4105VS8	Flagellar biosynthetic protein fliq
B2B01_RS07870	ENOG4105CN7	Flagellar biosynthetic protein FliP
B2B01_RS07880	ENOG4105DD5	Flagellar motor switch protein
B2B01_RS07885	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
B2B01_RS07890	ENOG4107ZI8	flagellar basal body-associated protein flil
B2B01_RS07905	ENOG4108JIR	Flagellum-specific ATP synthase
B2B01_RS07910	ENOG4108CG0	Flagellar assembly protein
B2B01_RS07915	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
B2B01_RS07920	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
B2B01_RS07925	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
B2B01_RS07935	ENOG4105D00	flagellar biosynthetic protein flhB
B2B01_RS07950	ENOG4105MQ3	flagellar protein FliS
B2B01_RS07955	ENOG4105DTS	flagellar hook-associated
B2B01_RS07965	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
B2B01_RS07975	ENOG4105E96	Colicin v production protein
B2B01_RS07980	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
B2B01_RS07985	ENOG4105E32	cytoplasmic protein
B2B01_RS07995	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
B2B01_RS08000	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
B2B01_RS08005	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
B2B01_RS08010	ENOG4105CE9	30S ribosomal protein S2
B2B01_RS08015	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
B2B01_RS08020	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
B2B01_RS08025	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
B2B01_RS08030	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
B2B01_RS08035	ENOG4105KNE	Phosphatidate cytidylyltransferase
B2B01_RS08040	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
B2B01_RS08045	ENOG4105DZP	Membrane-associated zinc metalloprotease
B2B01_RS08050	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B2B01_RS08055	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
B2B01_RS08060	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2B01_RS08065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
B2B01_RS08075	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2B01_RS08080	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B2B01_RS08085	ENOG4108RWN	rrna methyltransferase
B2B01_RS08095	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
B2B01_RS08100	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
B2B01_RS08115	ENOG4105BZU	Histidine kinase
B2B01_RS08120	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
B2B01_RS08125	ENOG4108Z1B	Cyclase dehydrase
B2B01_RS08135	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS08140	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B2B01_RS08145	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2B01_RS08160	ENOG4105HHA	aminodeoxychorismate lyase
B2B01_RS08165	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
B2B01_RS08170	ENOG4107QMP	dna polymerase iii subunits gamma and tau
B2B01_RS08175	ENOG4105F8V	Hydrolase, tatD family
B2B01_RS08210	ENOG4105CW0	outer membrane usher protein
B2B01_RS08215	ENOG4108MQF	Chaperone
B2B01_RS08225	ENOG4106UCC	Fimbrial protein
B2B01_RS08240	ENOG4105BZU	Histidine kinase
B2B01_RS08265	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
B2B01_RS08270	ENOG4105MSY	salicylate hydroxylase
B2B01_RS08280	ENOG4105BZU	Histidine kinase
B2B01_RS08295	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
B2B01_RS08330	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
B2B01_RS08335	ENOG4108KB2	LysR family Transcriptional regulator
B2B01_RS08340	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2B01_RS08345	ENOG4105HSS	phospholipase C
B2B01_RS08365	ENOG4105NQN	cytochrome C
B2B01_RS08380	ENOG4105F2V	VRR-NUC domain-containing protein
B2B01_RS08395	ENOG4105D0S	secretion protein (HlyD
B2B01_RS08400	ENOG4105CJ1	ABC, transporter
B2B01_RS08405	ENOG4105CMI	transporter
B2B01_RS08415	ENOG4108VGI	doxx family
B2B01_RS08435	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS08440	ENOG4105CSH	Transporter
B2B01_RS08450	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
B2B01_RS08470	ENOG410846T	CoA-transferase family III
B2B01_RS08475	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
B2B01_RS08480	ENOG4105WAP	TPR repeat-containing protein
B2B01_RS08495	ENOG4105DF9	Lipoate-protein, ligase
B2B01_RS08505	ENOG4105D82	Glutamate dehydrogenase
B2B01_RS08510	ENOG4107SQD	Transcriptional regulator, GntR family
B2B01_RS08515	ENOG4105CSH	Transporter
B2B01_RS08520	ENOG41066VF	YeeE YedE family protein
B2B01_RS08525	ENOG4105KHC	sulfurtransferase
B2B01_RS08540	ENOG4108UZX	fmn reductase
B2B01_RS08545	ENOG4105DEN	Luciferase family
B2B01_RS08565	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS08580	ENOG4105NTW	Transcriptional regulator
B2B01_RS08590	ENOG4105NIV	Esterase
B2B01_RS08595	ENOG4107RNH	Outer membrane receptor FepA
B2B01_RS08620	ENOG4105E9K	Isocitrate dehydrogenase
B2B01_RS08640	ENOG4105CDA	abc transporter atp-binding protein
B2B01_RS08645	ENOG4105E5Q	amino acid AbC transporter
B2B01_RS08650	ENOG4105EAB	amino acid AbC transporter
B2B01_RS08660	ENOG4105BZU	Histidine kinase
B2B01_RS08675	ENOG4105EE5	Membrane protein terC
B2B01_RS08685	ENOG4108WQH	regulatoR
B2B01_RS08690	ENOG4105BZU	Histidine kinase
B2B01_RS08700	ENOG4107YCY	Transcriptional regulator
B2B01_RS08705	ENOG4105C7K	acetolactate synthase
B2B01_RS08715	ENOG4105DJ4	phosphatidylserine decarboxylase
B2B01_RS08725	ENOG4105D01	(LipO)protein
B2B01_RS08730	ENOG4108YYQ	gCN5-related N-acetyltransferase
B2B01_RS08735	ENOG4105VEJ	Heat shock protein
B2B01_RS08745	ENOG4108SXK	Transporter Drug Metabolite Exporter family
B2B01_RS08750	ENOG4108K3A	Glutathione S-transferase
B2B01_RS08760	ENOG4108IV0	ABC, transporter
B2B01_RS08765	ENOG4105C0Z	ABC transporter
B2B01_RS08770	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2B01_RS08775	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS08780	ENOG4105CP9	extracellular ligand-binding receptor
B2B01_RS08790	ENOG4105EX9	Membrane
B2B01_RS08795	ENOG4105II7	pyrroline-5-carboxylate reductase
B2B01_RS08800	ENOG4105BZ7	extracellular solute-binding protein family 1
B2B01_RS08815	ENOG4108IJ9	(ABC) transporter
B2B01_RS08820	ENOG4105CP9	extracellular ligand-binding receptor
B2B01_RS08860	ENOG4108IY8	ABC, transporter
B2B01_RS08870	ENOG4105KME	endoribonuclease L-psp
B2B01_RS08885	ENOG4105C6F	GntR Family Transcriptional Regulator
B2B01_RS08890	ENOG4105C26	Dehydrogenase
B2B01_RS08895	ENOG4105JQN	Transcriptional regulator
B2B01_RS08900	ENOG4105C5Q	Transcriptional regulator
B2B01_RS08905	ENOG4105CB5	ATP-dependent DNA helicase recG
B2B01_RS08910	ENOG4105KME	endoribonuclease L-psp
B2B01_RS08915	ENOG4105DP0	ferredoxin-NADP reductase
B2B01_RS08920	ENOG4107QKW	extracellular solute-binding protein family 1
B2B01_RS08930	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS08935	ENOG4105EUB	pirin domain protein
B2B01_RS08945	ENOG4105EQ1	Transcriptional regulator
B2B01_RS08950	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
B2B01_RS08955	ENOG4105CUX	Signal transduction histidine kinase
B2B01_RS08965	ENOG4105CSA	Coproporphyrinogen iii oxidase
B2B01_RS08970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
B2B01_RS08975	ENOG4105BZU	Histidine kinase
B2B01_RS08980	ENOG4105C8Q	Methyl-accepting chemotaxis
B2B01_RS08990	ENOG4105DSJ	YicC domain protein
B2B01_RS08995	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
B2B01_RS09010	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B2B01_RS09045	ENOG4108XG2	Histidine kinase
B2B01_RS09060	ENOG4105FYV	Amp nucleosidase
B2B01_RS09065	ENOG4107TT5	NLP P60 protein
B2B01_RS09070	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
B2B01_RS09075	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
B2B01_RS09080	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
B2B01_RS09085	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
B2B01_RS09090	ENOG4105CDA	abc transporter atp-binding protein
B2B01_RS09095	ENOG4105E5Q	amino acid AbC transporter
B2B01_RS09100	ENOG4107R0W	ABC transporter
B2B01_RS09105	ENOG4108YH7	hemolysin
B2B01_RS09120	ENOG4105GQR	Chaperone
B2B01_RS09130	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS09130	ENOG4108QZZ	filamentous hemagglutinin
B2B01_RS09135	ENOG4108I0Y	(ABC) transporter
B2B01_RS09140	ENOG4108UJV	acyl-CoA thioesterase i
B2B01_RS09145	ENOG4105EIN	peptidylprolyl cis-trans isomerase
B2B01_RS09150	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
B2B01_RS09155	ENOG4105D6S	protein involved in catabolism of external DNA
B2B01_RS09165	ENOG4105EHV	domain protein
B2B01_RS09180	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
B2B01_RS09195	ENOG4108K5P	(LipO)protein
B2B01_RS09200	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
B2B01_RS09205	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
B2B01_RS09210	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
B2B01_RS09215	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
B2B01_RS09220	ENOG4105C7N	Xanthine uracil vitamin C permease
B2B01_RS09225	ENOG4105DEN	Luciferase family
B2B01_RS09230	ENOG4105K63	Thioredoxin
B2B01_RS09260	ENOG4105C5H	ABC transporter
B2B01_RS09265	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
B2B01_RS09270	ENOG4108Z6B	deaminase
B2B01_RS09275	ENOG4106TCE	
B2B01_RS09285	ENOG4105KJM	monovalent cation h antiporter subunit g
B2B01_RS09290	ENOG4105W4C	monovalent cation H antiporter subunit F
B2B01_RS09295	ENOG4105SC1	monovalent cation H antiporter subunit E
B2B01_RS09300	ENOG4107R4Z	monovalent cation h antiporter subunit d
B2B01_RS09305	ENOG4108ZE9	Monovalent cation H antiporter subunit C
B2B01_RS09310	ENOG4105D65	subunit l
B2B01_RS09325	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2B01_RS09330	ENOG4105EW9	transcriptional regulator AsnC family
B2B01_RS09345	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
B2B01_RS09350	ENOG4105E98	transcriptional regulator DeoR family
B2B01_RS09355	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
B2B01_RS09360	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
B2B01_RS09385	ENOG4108YZN	class I peptide chain release factor
B2B01_RS09395	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
B2B01_RS09410	ENOG4105DSW	Fusaric acid resistance protein
B2B01_RS09420	ENOG4105Y49	secretion protein, HlyD family
B2B01_RS09430	ENOG4106KED	esterase YpfH
B2B01_RS09445	ENOG4105C0B	DNA polymerase III (alpha subunit)
B2B01_RS09450	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2B01_RS09465	ENOG4105KTH	gatB Yqey
B2B01_RS09470	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
B2B01_RS09490	ENOG4108JQC	penicillin-binding protein 1A
B2B01_RS09495	ENOG4108R1E	Serine threonine protein phosphatase 1
B2B01_RS09510	ENOG4107UNS	conserved inner membrane protein
B2B01_RS09545	ENOG4108ZJF	Glcg protein
B2B01_RS09570	ENOG4108YXU	transcriptional regulator AsnC family
B2B01_RS09585	ENOG4105C94	Transporter
B2B01_RS09610	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
B2B01_RS09615	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
B2B01_RS09620	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
B2B01_RS09625	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
B2B01_RS09630	ENOG4105VJV	50s ribosomal protein L35
B2B01_RS09635	ENOG4105C0P	Mg chelatase subunit ChlI
B2B01_RS09640	ENOG4105W0Z	cytoplasmic protein
B2B01_RS09655	ENOG4108YZA	Nitrogen regulatory protein pii
B2B01_RS09660	ENOG4105BZU	Histidine kinase
B2B01_RS09690	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
B2B01_RS09705	ENOG4105ECP	epimerase
B2B01_RS09710	ENOG4105C26	Dehydrogenase
B2B01_RS09720	ENOG4105DY2	Paraquat-inducible protein b
B2B01_RS09725	ENOG4105F1S	paraquat-inducible protein a
B2B01_RS09730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B2B01_RS09735	ENOG4108JQB	penicillin-binding protein 1C
B2B01_RS09745	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
B2B01_RS09750	ENOG4105VEQ	Cold shock protein
B2B01_RS09760	ENOG4105CHU	acetyl-coa acetyltransferase
B2B01_RS09765	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B2B01_RS09770	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B2B01_RS09780	ENOG4105M8F	Biopolymer transport protein exbD tolR
B2B01_RS09785	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
B2B01_RS09790	ENOG4105W49	UPF0434 protein
B2B01_RS09795	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
B2B01_RS09800	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
B2B01_RS09810	ENOG4105CJR	Integral membrane protein (MviN
B2B01_RS09820	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
B2B01_RS09825	ENOG4105C5I	Dehydrogenase
B2B01_RS09835	ENOG4105C8Y	Acetylornithine aminotransferase
B2B01_RS09840	ENOG4105DBV	ornithine carbamoyltransferase
B2B01_RS09855	ENOG4105DFH	Transport of potassium into the cell (By similarity)
B2B01_RS09860	ENOG4105DHQ	Histidine kinase
B2B01_RS09865	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
B2B01_RS09890	ENOG4105K70	DNA-binding protein
B2B01_RS09895	ENOG4105C28	cystathionine
B2B01_RS09900	ENOG4105C2N	RNA methyltransferase TrmH family group 3
B2B01_RS09905	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
B2B01_RS09930	ENOG4108HPG	-acetyltransferase
B2B01_RS09940	ENOG4105CUC	YeeE YedE family protein
B2B01_RS09950	ENOG4108PTX	LysR family Transcriptional regulator
B2B01_RS09955	ENOG4105CBC	glutamate synthase
B2B01_RS09965	ENOG4108KU3	Integrase
B2B01_RS09995	ENOG4105C2M	dna polymerase I
B2B01_RS10210	ENOG4106TD9	Diguanylate cyclase
B2B01_RS10215	ENOG4105BZU	Histidine kinase
B2B01_RS10225	ENOG4108MK9	spermidine N(1)-acetyltransferase
B2B01_RS10250	ENOG4105T86	cytochrome C
B2B01_RS10255	ENOG4107QTF	adenylosuccinate lyase
B2B01_RS10260	ENOG4108U78	Glutathione S-transferase
B2B01_RS10270	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
B2B01_RS10280	ENOG4105W8H	transhydrogenase (subunit alpha
B2B01_RS10285	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
B2B01_RS10290	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
B2B01_RS10295	ENOG4105EU8	FAD linked oxidase domain protein
B2B01_RS10300	ENOG4105CQB	FAD linked oxidase domain protein
B2B01_RS10305	ENOG4105CQB	FAD linked oxidase domain protein
B2B01_RS10310	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
B2B01_RS10315	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
B2B01_RS10320	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
B2B01_RS10330	ENOG4105CD8	aminopeptidase N
B2B01_RS10335	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
B2B01_RS10370	ENOG4105D6E	homoserine dehydrogenase
B2B01_RS10375	ENOG4105CHM	Aminotransferase
B2B01_RS10380	ENOG4108UIV	Protein of unknown function (DUF498/DUF598)
B2B01_RS10385	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2B01_RS10390	ENOG4108IAB	Phoh family
B2B01_RS10395	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
B2B01_RS10400	ENOG4105DHU	Bile acid
B2B01_RS10405	ENOG4105CDU	Replicative dna helicase
B2B01_RS10415	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
B2B01_RS10420	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
B2B01_RS10430	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
B2B01_RS10435	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
B2B01_RS10440	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
B2B01_RS10445	ENOG4105CTB	Polyprenyl synthetase
B2B01_RS10450	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
B2B01_RS10465	ENOG4105KHC	sulfurtransferase
B2B01_RS10475	ENOG4105D0M	Protease HtpX homolog
B2B01_RS10485	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
B2B01_RS10490	ENOG4106UX7	integral membrane protein
B2B01_RS10500	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
B2B01_RS10505	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
B2B01_RS10510	ENOG4105CW7	secretion protein, HlyD family
B2B01_RS10515	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2B01_RS10520	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B2B01_RS10530	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS10535	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS10540	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS10545	ENOG4108JQ6	ABC transporter
B2B01_RS10550	ENOG4108JPW	Aminotransferase
B2B01_RS10555	ENOG4105K8K	Cupin 2, conserved barrel
B2B01_RS10565	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
B2B01_RS10575	ENOG4105C26	Dehydrogenase
B2B01_RS10580	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
B2B01_RS10595	ENOG4105CDY	transcriptional regulatory protein
B2B01_RS10600	ENOG4105C12	Phosphoribosylglycinamide synthetase
B2B01_RS10610	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
B2B01_RS10615	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
B2B01_RS10620	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
B2B01_RS10625	ENOG4108Z03	MAF-like protein
B2B01_RS10645	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
B2B01_RS10650	ENOG4105CK2	sodium dicarboxylate symporter
B2B01_RS10675	ENOG4105EST	Metal Dependent Phosphohydrolase
B2B01_RS10685	ENOG4105CSH	Transporter
B2B01_RS10695	ENOG4105DND	Transcriptional regulator
B2B01_RS10730	ENOG4105C03	ribonuclease
B2B01_RS10735	ENOG4105BZ1	(ABC) transporter
B2B01_RS10750	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
B2B01_RS10755	ENOG4107BJW	polysaccharide deacetylase
B2B01_RS10760	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
B2B01_RS10765	ENOG4106WTF	Glycosyl transferase, family 2
B2B01_RS10770	ENOG4107BJW	polysaccharide deacetylase
B2B01_RS10775	ENOG4105CPK	Glycosyl transferase (Group 1
B2B01_RS10780	ENOG4105C0B	DNA polymerase III (alpha subunit)
B2B01_RS10790	ENOG4105CQ7	ATP-dependent helicase
B2B01_RS10795	ENOG4108EKC	n-acetylglutamate synthase
B2B01_RS10800	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
B2B01_RS10810	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
B2B01_RS10815	ENOG4105E66	phosphoriboisomerase A
B2B01_RS10820	ENOG4107QSV	RmuC domain protein
B2B01_RS10830	ENOG4108RB4	3-methyladenine DNA glycosylase
B2B01_RS10840	ENOG4105D38	putrescine abc transporter
B2B01_RS10845	ENOG4105F38	ABC transporter, permease
B2B01_RS10850	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS10860	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
B2B01_RS10865	ENOG4105CV6	ABC transporter, permease
B2B01_RS10870	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
B2B01_RS10880	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
B2B01_RS10905	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
B2B01_RS10910	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
B2B01_RS10920	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
B2B01_RS10925	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
B2B01_RS10930	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
B2B01_RS10940	ENOG4105D0M	Protease HtpX homolog
B2B01_RS10945	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
B2B01_RS10950	ENOG4105BZU	Histidine kinase
B2B01_RS10965	ENOG4105CNG	UPF0061 protein
B2B01_RS10970	ENOG4107S2Z	UPF0761 membrane protein
B2B01_RS10980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B2B01_RS10985	ENOG4105CUV	Homoserine Kinase
B2B01_RS11050	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
B2B01_RS11065	ENOG4105F0N	pyrophosphate phospho-hydrolase
B2B01_RS11085	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
B2B01_RS11090	ENOG4108ZCF	integral membrane protein
B2B01_RS11095	ENOG4108ZCF	integral membrane protein
B2B01_RS11100	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
B2B01_RS11105	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
B2B01_RS11115	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
B2B01_RS11120	ENOG4105DZ2	Transcriptional regulator
B2B01_RS11125	ENOG4108004	Modulates RecA activity (By similarity)
B2B01_RS11130	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
B2B01_RS11140	ENOG4105DHQ	Histidine kinase
B2B01_RS11145	ENOG4105CSH	Transporter
B2B01_RS11150	ENOG4105DH7	May be involved in recombination (By similarity)
B2B01_RS11155	ENOG4105CXT	aspartate transcarbamylase
B2B01_RS11185	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2B01_RS11200	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
B2B01_RS11215	ENOG4105VEQ	Cold shock protein
B2B01_RS11435	ENOG41076J9	exonuclease VIII
B2B01_RS11440	ENOG4108PNI	recT protein
B2B01_RS11480	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
B2B01_RS11490	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2B01_RS11500	ENOG4105VCC	30S ribosomal protein S21
B2B01_RS11510	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
B2B01_RS11515	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
B2B01_RS11520	ENOG4105EPW	hflc protein
B2B01_RS11525	ENOG4107QJR	hflk protein
B2B01_RS11530	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
B2B01_RS11535	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
B2B01_RS11540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B2B01_RS11545	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
B2B01_RS11550	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B2B01_RS11555	ENOG4105N21	Membrane
B2B01_RS11560	ENOG4105CUT	histidyl-tRNA synthetase
B2B01_RS11575	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
B2B01_RS11580	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
B2B01_RS11585	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
B2B01_RS11590	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
B2B01_RS11595	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
B2B01_RS11600	ENOG4105K5M	30s ribosomal protein S16
B2B01_RS11610	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
B2B01_RS11615	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
B2B01_RS11665	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
B2B01_RS11670	ENOG4108EX3	reductase
B2B01_RS11675	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
B2B01_RS11680	ENOG4105KPY	Small multidrug resistance protein
B2B01_RS11685	ENOG4105QVC	MOSC domain-containing protein
B2B01_RS11690	ENOG4105EV8	ectoine hydroxylase
B2B01_RS11695	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
B2B01_RS11705	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
B2B01_RS11715	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2B01_RS11725	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2B01_RS11730	ENOG4105K63	Thioredoxin
B2B01_RS11735	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
B2B01_RS11745	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
B2B01_RS11750	ENOG4105WPN	DNA integration recombination invertion protein
B2B01_RS11755	ENOG4105EJQ	L-serine dehydratase
B2B01_RS11760	ENOG4105EAM	Na Pi-cotransporter
B2B01_RS11765	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
B2B01_RS11775	ENOG4105C2M	dna polymerase I
B2B01_RS11790	ENOG4105CI3	gtp-binding protein typa
B2B01_RS11795	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
B2B01_RS11800	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
B2B01_RS11805	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
B2B01_RS11810	ENOG4105CHV	Transcription elongation factor NusA
B2B01_RS11815	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
B2B01_RS11825	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
B2B01_RS11835	ENOG4105CKI	cobalamin synthesis protein
B2B01_RS11850	ENOG4108RXX	maleylacetoacetate isomerase
B2B01_RS11855	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
B2B01_RS11865	ENOG4105W5Q	DNA repair protein (RadC
B2B01_RS11870	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
B2B01_RS11875	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
B2B01_RS11890	ENOG4107QI1	Mate efflux family protein
B2B01_RS11905	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
B2B01_RS11915	ENOG4105CHR	reductase
B2B01_RS11920	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
B2B01_RS11925	ENOG4105FE1	phytoene synthase
B2B01_RS11935	ENOG4105CVN	desaturase
B2B01_RS11955	ENOG4107RSM	transcriptional regulator
B2B01_RS11960	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
B2B01_RS11965	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
B2B01_RS11980	ENOG4108YZ4	nudix hydrolase
B2B01_RS11990	ENOG4106P55	Transcriptional regulator
B2B01_RS11995	ENOG4105VRT	cytoplasmic protein
B2B01_RS12035	ENOG4105D94	Major Facilitator Superfamily
B2B01_RS12045	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
B2B01_RS12050	ENOG4105BZU	Histidine kinase
B2B01_RS12055	ENOG4105IPI	Membrane
B2B01_RS12060	ENOG4105E3A	(ABC) transporter
B2B01_RS12065	ENOG4105DA5	(ABC) transporter
B2B01_RS12070	ENOG4108ZHJ	Organic hydroperoxide resistance protein
B2B01_RS12075	ENOG4105K56	Transcriptional regulator
B2B01_RS12080	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
B2B01_RS12085	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
B2B01_RS12095	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
B2B01_RS12110	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
B2B01_RS12120	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
B2B01_RS12125	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
B2B01_RS12130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
B2B01_RS12135	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
B2B01_RS12140	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
B2B01_RS12145	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2B01_RS12150	ENOG4105BZS	acriflavin resistance protein
B2B01_RS12155	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
B2B01_RS12160	ENOG4107EXC	regulatoR
B2B01_RS12170	ENOG4105F4R	Transcriptional regulator mode
B2B01_RS12175	ENOG4108IJ6	ABC transporter
B2B01_RS12180	ENOG4105E0C	molybdate abc transporter
B2B01_RS12185	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
B2B01_RS12195	ENOG4105C7J	ABC transporter, permease
B2B01_RS12210	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
B2B01_RS12225	ENOG4105CHU	acetyl-coa acetyltransferase
B2B01_RS12235	ENOG4108IJ7	Glycine betaine
B2B01_RS12240	ENOG4108HQS	Glycine betaine
B2B01_RS12250	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
B2B01_RS12255	ENOG4105C2C	drug resistance transporter, Bcr CflA
B2B01_RS12260	ENOG4105KDC	50s ribosomal protein l28
B2B01_RS12265	ENOG4105W0E	50S ribosomal protein L33
B2B01_RS12285	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
B2B01_RS12295	ENOG4105C8T	Leucyl-tRNA synthetase
B2B01_RS12310	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
B2B01_RS12325	ENOG4105EUF	amidase EC 3.5.1.4
B2B01_RS12370	ENOG4105CYC	Transferase
B2B01_RS12375	ENOG4105CMU	LysR family (Transcriptional regulator
B2B01_RS12380	ENOG4105EGS	Mechanosensitive ion channel
B2B01_RS12390	ENOG4108594	Permease of the drug metabolite transporter
B2B01_RS12410	ENOG4107QIJ	Aconitate hydratase 2
B2B01_RS12415	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
B2B01_RS12440	ENOG4107QM5	aconitate hydratase
B2B01_RS12445	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
B2B01_RS12460	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
B2B01_RS12465	ENOG4105EMU	Dehydrogenase
B2B01_RS12475	ENOG4105F27	Major Facilitator
B2B01_RS12480	ENOG4105CC0	LysR family Transcriptional regulator
B2B01_RS12545	ENOG4105BZU	Histidine kinase
B2B01_RS12565	ENOG4108JQ6	ABC transporter
B2B01_RS12570	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS12580	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
B2B01_RS12590	ENOG4105D7N	magnesium and cobalt transport protein CorA
B2B01_RS12600	ENOG4105I3N	Conserved Protein
B2B01_RS12610	ENOG4108JPW	Aminotransferase
B2B01_RS12615	ENOG4105C26	Dehydrogenase
B2B01_RS12620	ENOG4105ECY	inositol monophosphatase
B2B01_RS12625	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
B2B01_RS12630	ENOG4105D7W	serine acetyltransferase
B2B01_RS12640	ENOG4105CHU	acetyl-coa acetyltransferase
B2B01_RS12655	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
B2B01_RS12685	ENOG4105ED4	portal protein
B2B01_RS12855	ENOG4105DFP	Integrase
B2B01_RS12865	ENOG4105CFH	Aspartokinase
B2B01_RS12875	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
B2B01_RS12885	ENOG4105C8N	cysteinyl-tRNA synthetase
B2B01_RS12895	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
B2B01_RS12900	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
B2B01_RS12905	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
B2B01_RS12910	ENOG4105EE5	Membrane protein terC
B2B01_RS12915	ENOG4105ECY	inositol monophosphatase
B2B01_RS12920	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
B2B01_RS12945	ENOG4105D64	Mechanosensitive ion channel
B2B01_RS12995	ENOG4105DRR	Transcriptional regulator, GntR family
B2B01_RS13015	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
B2B01_RS13020	ENOG4105EZE	Cupin 4 family protein
B2B01_RS13030	ENOG4105GJM	(LipO)protein
B2B01_RS13035	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B2B01_RS13040	ENOG4108Z4T	Peptidase M50
B2B01_RS13045	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
B2B01_RS13050	ENOG4105CGZ	zinc metallopeptidase
B2B01_RS13090	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
B2B01_RS13095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
B2B01_RS13155	ENOG4105E5D	amino acid
B2B01_RS13160	ENOG41060V2	Acid-resistance protein
B2B01_RS13165	ENOG4105CVK	Glutamate decarboxylase
B2B01_RS13170	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
B2B01_RS13175	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
B2B01_RS13190	ENOG4105EJG	cellulose synthase
B2B01_RS13195	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
B2B01_RS13200	ENOG4107EEX	Cellulose synthase regulator protein
B2B01_RS13205	ENOG4107EEX	Cellulose synthase regulator protein
B2B01_RS13210	ENOG4107QZ7	Cellulose synthase catalytic subunit
B2B01_RS13215	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
B2B01_RS13245	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
B2B01_RS13250	ENOG4105DAY	polysaccharide export protein
B2B01_RS13325	ENOG4108IPW	abc transporter atp-binding protein
B2B01_RS13330	ENOG4105CM4	permease protein
B2B01_RS13335	ENOG4105DHS	permease protein
B2B01_RS13345	ENOG4105NTZ	Preprotein translocase subunit SecG
B2B01_RS13350	ENOG4105CP7	Triose-phosphate isomerase
B2B01_RS13380	ENOG4105C7B	Threonine dehydratase
B2B01_RS13390	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS13395	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
B2B01_RS13400	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
B2B01_RS13410	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
B2B01_RS13415	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
B2B01_RS13420	ENOG4108ZP8	Acetolactate synthase small subunit
B2B01_RS13425	ENOG4105C7K	acetolactate synthase
B2B01_RS13435	ENOG4105D1Q	UPF0246 protein
B2B01_RS13440	ENOG4105DTD	Dehydrogenase
B2B01_RS13450	ENOG4108V62	Rhodanese domain protein
B2B01_RS13455	ENOG41080HT	Transcriptional regulator, arsr family
B2B01_RS13460	ENOG4105CSR	polyphosphate kinase 2
B2B01_RS13465	ENOG4105BZU	Histidine kinase
B2B01_RS13485	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
B2B01_RS13490	ENOG4105D5Q	Arginine ornithine antiporter
B2B01_RS13495	ENOG4105CXN	decarboxylase
B2B01_RS13510	ENOG4105D1H	recombination factor protein RarA
B2B01_RS13520	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
B2B01_RS13525	ENOG4105CNU	cell division protein FtsK
B2B01_RS13530	ENOG4105C3M	thioredoxin reductase
B2B01_RS13535	ENOG4105C98	muts2 protein
B2B01_RS13545	ENOG4107QN1	sodium solute
B2B01_RS13560	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B2B01_RS13565	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
B2B01_RS13570	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
B2B01_RS13575	ENOG4105C08	Histidine kinase
B2B01_RS13580	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
B2B01_RS13595	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
B2B01_RS13610	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
B2B01_RS13630	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
B2B01_RS13635	ENOG4105CFG	Acts as a chaperone (By similarity)
B2B01_RS13645	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
B2B01_RS13655	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
B2B01_RS13660	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
B2B01_RS13665	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
B2B01_RS13670	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
B2B01_RS13675	ENOG41090R7	Ferric uptake
B2B01_RS13680	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
B2B01_RS13700	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
B2B01_RS13705	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B2B01_RS13710	ENOG4105EWC	Purine nucleoside phosphorylase
B2B01_RS13720	ENOG4108I0Z	Aconitate hydratase
B2B01_RS13725	ENOG4105C7F	AcnD-accessory protein PrpF
B2B01_RS13730	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2B01_RS13755	ENOG4106NZI	LysR family Transcriptional regulator
B2B01_RS13760	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B2B01_RS13765	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
B2B01_RS13770	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
B2B01_RS13775	ENOG4105C8Y	Acetylornithine aminotransferase
B2B01_RS13785	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
B2B01_RS13795	ENOG4105DFA	alanine racemase domain protein
B2B01_RS13800	ENOG4105DKK	Benzoate
B2B01_RS13815	ENOG4106NZI	LysR family Transcriptional regulator
B2B01_RS13860	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
B2B01_RS13895	ENOG4105W5Q	DNA repair protein (RadC
B2B01_RS13955	ENOG4105C0D	helicase
B2B01_RS13960	ENOG4105ESI	atpase involved in dna repair
B2B01_RS13970	ENOG4107QMH	DNA methylase
B2B01_RS14090	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
B2B01_RS14095	ENOG4107YH6	single-stranded DNA-binding protein
B2B01_RS14165	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
B2B01_RS14175	ENOG4108UAU	isochorismatase
B2B01_RS14190	ENOG4105RE0	Asp Glu hydantoin racemase
B2B01_RS14220	ENOG4105CC0	LysR family Transcriptional regulator
B2B01_RS14230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
B2B01_RS14235	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
B2B01_RS14240	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
B2B01_RS14255	ENOG41069M3	Transcriptional regulator
B2B01_RS14260	ENOG4107TH8	cina domain protein
B2B01_RS14275	ENOG4105C1J	atp-dependent rna helicase
B2B01_RS14300	ENOG4105DNZ	Alpha Beta Hydrolase
B2B01_RS14305	ENOG4105ERG	peptidase m48, ste24p
B2B01_RS14315	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
B2B01_RS14335	ENOG4107RAQ	aminopeptidase
B2B01_RS14340	ENOG4105D0A	hydroxylase
B2B01_RS14345	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
B2B01_RS14360	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
B2B01_RS14365	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
B2B01_RS14375	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
B2B01_RS14380	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B2B01_RS14410	ENOG4105CX6	glutaminyL-tRNA synthetase
B2B01_RS14415	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
B2B01_RS14420	ENOG4107QMS	site-determining protein
B2B01_RS14425	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
B2B01_RS14440	ENOG4105C5H	ABC transporter
B2B01_RS14445	ENOG4105CSV	Glutaminase
B2B01_RS14450	ENOG4105E5D	amino acid
B2B01_RS14455	ENOG41060V2	Acid-resistance protein
B2B01_RS14460	ENOG4105CVK	Glutamate decarboxylase
B2B01_RS14475	ENOG4108JQ7	(ABC) transporter
B2B01_RS14480	ENOG4105C3U	ABC transporter
B2B01_RS14485	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS14495	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS14500	ENOG4108SHN	Glycosyl transferase, family 2
B2B01_RS14510	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
B2B01_RS14515	ENOG4105CRQ	synthase (Component I)
B2B01_RS14525	ENOG4105CUZ	uba thif-type nad fad binding protein
B2B01_RS14530	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2B01_RS14535	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
B2B01_RS14550	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
B2B01_RS14570	ENOG4105D5U	fad dependent oxidoreductase
B2B01_RS14580	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
B2B01_RS14630	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS14635	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2B01_RS14640	ENOG4105C0Z	ABC transporter
B2B01_RS14645	ENOG4108IV0	ABC, transporter
B2B01_RS14650	ENOG4105E0M	Sulfatase
B2B01_RS14660	ENOG4105FN4	Depolymerizes alginate by cleaving the beta-1,4 glycosidic bond (By similarity)
B2B01_RS14685	ENOG4105MP9	class II Aldolase
B2B01_RS14705	ENOG41066T0	asmA family
B2B01_RS14710	ENOG4108R3E	Dna-3-methyladenine glycosylase i
B2B01_RS14715	ENOG4105PI0	Ferredoxin
B2B01_RS14725	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
B2B01_RS14735	ENOG4105D01	(LipO)protein
B2B01_RS14740	ENOG4108UMI	ABC transporter, permease
B2B01_RS14745	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS14750	ENOG4105CJQ	hydrolase, family 31
B2B01_RS14755	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
B2B01_RS14760	ENOG4105ECY	inositol monophosphatase
B2B01_RS14765	ENOG4105CEY	Amp-dependent synthetase and ligase
B2B01_RS14770	ENOG4105CH2	amidohydrolase
B2B01_RS14780	ENOG4105HMI	Membrane
B2B01_RS14785	ENOG4105NAU	thioesterase Superfamily protein
B2B01_RS14790	ENOG4105CJW	magnesium transporter
B2B01_RS14805	ENOG4108XM1	transcriptional regulator AsnC family
B2B01_RS14820	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
B2B01_RS14825	ENOG4105DR5	peptidase
B2B01_RS14840	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
B2B01_RS14845	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
B2B01_RS14850	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
B2B01_RS14855	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
B2B01_RS14860	ENOG4105CPF	Cell wall formation (By similarity)
B2B01_RS14865	ENOG4105DFU	Cell wall formation (By similarity)
B2B01_RS14870	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
B2B01_RS14880	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
B2B01_RS14885	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
B2B01_RS14890	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
B2B01_RS14900	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
B2B01_RS14905	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
B2B01_RS14910	ENOG4108V6E	Cell division protein mraZ
B2B01_RS14920	ENOG4105C5H	ABC transporter
B2B01_RS14925	ENOG4105EKE	dihydroorotase
B2B01_RS14930	ENOG4105CH2	amidohydrolase
B2B01_RS14970	ENOG4105EW9	transcriptional regulator AsnC family
B2B01_RS14975	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
B2B01_RS14985	ENOG4105W2Z	cytochrome C, class I
B2B01_RS14990	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
B2B01_RS15025	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
B2B01_RS15030	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
B2B01_RS15035	ENOG4105EXG	Transcriptional regulator
B2B01_RS15060	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
B2B01_RS15065	ENOG4107YD3	Thioesterase
B2B01_RS15070	ENOG4105E02	MotA TolQ exbB proton channel
B2B01_RS15085	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
B2B01_RS15090	ENOG4105KCK	Peptidoglycan-associated lipoprotein
B2B01_RS15105	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
B2B01_RS15120	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
B2B01_RS15125	ENOG4105T38	integral membrane protein
B2B01_RS15170	ENOG4107RZZ	dna polymerase iii epsilon subunit
B2B01_RS15175	ENOG4105BZS	acriflavin resistance protein
B2B01_RS15180	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
B2B01_RS15185	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
B2B01_RS15190	ENOG4105D1A	Methyltransferase
B2B01_RS15200	ENOG4105E9H	Lytic Murein transglycosylase
B2B01_RS15205	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
B2B01_RS15220	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
B2B01_RS15265	ENOG4105CNV	Aldolase
B2B01_RS15280	ENOG4105ED1	spovr family
B2B01_RS15285	ENOG4106AKX	UPF0229 protein
B2B01_RS15290	ENOG4105CYN	Serine protein kinase
B2B01_RS15300	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
B2B01_RS15315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
B2B01_RS15320	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
B2B01_RS15330	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
B2B01_RS15340	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
B2B01_RS15345	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
B2B01_RS15355	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
B2B01_RS15360	ENOG4108UJD	30S ribosomal protein S9
B2B01_RS15365	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
B2B01_RS15370	ENOG4105CH5	extracellular solute-binding protein, family 7
B2B01_RS15380	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
B2B01_RS15385	ENOG4105N42	UPF0307 protein
B2B01_RS15395	ENOG4105CD5	CoA-binding domain protein
B2B01_RS15395	ENOG4105CD5	CoA-binding domain protein
B2B01_RS15400	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
B2B01_RS15405	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2B01_RS15415	ENOG4105J0Q	Transcriptional regulator
B2B01_RS15425	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B2B01_RS15430	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
B2B01_RS15445	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
B2B01_RS15450	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
B2B01_RS15480	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
B2B01_RS15485	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
B2B01_RS15490	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
B2B01_RS15495	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
B2B01_RS15500	ENOG4107ZT5	Thiol disulfide interchange protein
B2B01_RS15505	ENOG4105DFU	Cell wall formation (By similarity)
B2B01_RS15510	ENOG4105IPS	esterase
B2B01_RS15525	ENOG4105E2X	shikimate dehydrogenase
B2B01_RS15530	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
B2B01_RS15540	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
B2B01_RS15545	ENOG4108Z20	Acyl-transferase
B2B01_RS15550	ENOG4105CD3	dihydroorotase
B2B01_RS15560	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
B2B01_RS15565	ENOG4108UJU	UPF0301 protein
B2B01_RS15570	ENOG4105VCQ	rubredoxin
B2B01_RS15575	ENOG4105DWF	phosphomethylpyrimidine kinase
B2B01_RS15580	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
B2B01_RS15585	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
B2B01_RS15610	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS15615	ENOG4108UKI	Enoyl-CoA hydratase
B2B01_RS15620	ENOG4105DTD	Dehydrogenase
B2B01_RS15630	ENOG4105BZU	Histidine kinase
B2B01_RS15650	ENOG4108IV0	ABC, transporter
B2B01_RS15655	ENOG4105C0Z	ABC transporter
B2B01_RS15660	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
B2B01_RS15665	ENOG4105C32	Amino acid ABC transporter (Permease)
B2B01_RS15700	ENOG4105X0I	Fimbrial
B2B01_RS15705	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
B2B01_RS15710	ENOG4105BZS	acriflavin resistance protein
B2B01_RS15725	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
B2B01_RS15730	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
B2B01_RS15735	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
B2B01_RS15745	ENOG4108Q9V	regulatoR
B2B01_RS15750	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
B2B01_RS15755	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
B2B01_RS15765	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2B01_RS15785	ENOG4105CDA	abc transporter atp-binding protein
B2B01_RS15790	ENOG4105DRP	amino acid AbC transporter
B2B01_RS15795	ENOG4105EZ7	amino acid ABC transporter
B2B01_RS15800	ENOG4107QXX	ABC transporter
B2B01_RS15805	ENOG4105CAK	Cell division ATP-binding protein ftsE
B2B01_RS15810	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
B2B01_RS15815	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
B2B01_RS15825	ENOG4105CEN	a g-specific adenine glycosylase
B2B01_RS15835	ENOG4105F2W	methyltransferase
B2B01_RS15840	ENOG4105C3R	Methionine synthase
B2B01_RS15845	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
B2B01_RS15850	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
B2B01_RS15855	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
B2B01_RS15860	ENOG4105DWF	phosphomethylpyrimidine kinase
B2B01_RS15865	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
B2B01_RS15870	ENOG4105DFG	type I secretion outer membrane protein
B2B01_RS15875	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
B2B01_RS15885	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
B2B01_RS15895	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
B2B01_RS15900	ENOG4105D3Q	Sugar transferase
B2B01_RS15925	ENOG4105CHR	reductase
B2B01_RS15930	ENOG4108P1X	synthase
B2B01_RS15955	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
B2B01_RS15960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
B2B01_RS15965	ENOG4105BZU	Histidine kinase
B2B01_RS15975	ENOG4108JQ1	Dehydrogenase
B2B01_RS15980	ENOG4107RSM	transcriptional regulator
B2B01_RS15990	ENOG4105P4J	Allophanate hydrolase, subunit 1
B2B01_RS16005	ENOG4105DRR	Transcriptional regulator, GntR family
B2B01_RS16015	ENOG4105W39	Membrane
B2B01_RS16020	ENOG4105C7B	Threonine dehydratase
B2B01_RS16025	ENOG4108Z9W	Outer membrane porin
B2B01_RS16030	ENOG4105EXG	Transcriptional regulator
B2B01_RS16035	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
B2B01_RS16040	ENOG4108JJ8	(ABC) transporter
B2B01_RS16045	ENOG4108JJ9	ABC, transporter
B2B01_RS16055	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
B2B01_RS16060	ENOG4105C4M	(Ubiquinol oxidase) subunit I
B2B01_RS16070	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
B2B01_RS16075	ENOG4105C2X	Arabinose 5-phosphate isomerase
B2B01_RS16095	ENOG4108IUZ	ABC transporter
B2B01_RS16100	ENOG4105R8A	Heat shock protein
B2B01_RS16105	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
B2B01_RS16110	ENOG4105CF1	Alkylated DNA repair protein
B2B01_RS16115	ENOG4105DND	Transcriptional regulator
B2B01_RS16125	ENOG4105CH2	amidohydrolase
B2B01_RS16130	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
B2B01_RS16135	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
B2B01_RS16145	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
B2B01_RS16155	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
B2B01_RS16160	ENOG4105EHG	Permease protein
B2B01_RS16165	ENOG4107R4I	Periplasmic binding protein
B2B01_RS16170	ENOG4106QJH	hemin transport protein
B2B01_RS16185	ENOG4108SF5	RNA Polymerase
B2B01_RS16205	ENOG4108S4H	thioesterase Superfamily protein
B2B01_RS16220	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
B2B01_RS16225	ENOG4108MG3	formate dehydrogenase
B2B01_RS16230	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
B2B01_RS16240	ENOG4105EM7	Selenocysteine-specific translation elongation factor
B2B01_RS16255	ENOG4105ETT	transcriptional Regulator, LysR family
B2B01_RS16265	ENOG4105DK0	Indole-3-glycerol phosphate synthase
B2B01_RS16270	ENOG4108I0Q	anthranilate phosphoribosyltransferase
B2B01_RS16275	ENOG4105DDQ	anthranilate synthase
B2B01_RS16280	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
B2B01_RS16285	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
B2B01_RS16290	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
B2B01_RS16295	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
B2B01_RS16300	ENOG4105K6T	rare lipoprotein A
B2B01_RS16305	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
B2B01_RS16310	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
B2B01_RS16315	ENOG41082FP	UPF0102 protein
B2B01_RS16320	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
B2B01_RS16325	ENOG4105W4M	Transport-associated protein
B2B01_RS16335	ENOG4105D01	(LipO)protein
B2B01_RS16340	ENOG4105CAS	nag kinase
B2B01_RS16350	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
B2B01_RS16355	ENOG4107QPK	)-transporter
B2B01_RS16360	ENOG4105DG4	malate L-lactate dehydrogenase
B2B01_RS16365	ENOG4105CNI	cell division protein FtsW
B2B01_RS16370	ENOG4105CJN	penicillin-binding protein
B2B01_RS16380	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
B2B01_RS16390	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS16395	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS16400	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS16405	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
B2B01_RS16415	ENOG4105D82	Glutamate dehydrogenase
B2B01_RS16420	ENOG4105EN6	Membrane
B2B01_RS16430	ENOG4105EYM	Major Facilitator superfamily
B2B01_RS16440	ENOG4105DWV	Homoserine O-trans-acetylase
B2B01_RS16475	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
B2B01_RS16485	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS16495	ENOG4105EA8	2-Nitropropane dioxygenase
B2B01_RS16500	ENOG4105E39	Enoyl-CoA hydratase
B2B01_RS16505	ENOG41060WC	Enoyl-CoA hydratase
B2B01_RS16510	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
B2B01_RS16520	ENOG4105DEF	Extracellular solute-binding protein, family 5
B2B01_RS16525	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS16530	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS16540	ENOG4108JQ7	(ABC) transporter
B2B01_RS16550	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
B2B01_RS16555	ENOG4105C4R	Atp-dependent dna helicase
B2B01_RS16560	ENOG4105C25	Primosomal protein n'
B2B01_RS16565	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
B2B01_RS16575	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
B2B01_RS16580	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
B2B01_RS16585	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
B2B01_RS16590	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
B2B01_RS16595	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B2B01_RS16600	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B2B01_RS16605	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
B2B01_RS16610	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
B2B01_RS16620	ENOG4105E39	Enoyl-CoA hydratase
B2B01_RS16630	ENOG4105C3M	thioredoxin reductase
B2B01_RS16640	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
B2B01_RS16650	ENOG4108JQ1	Dehydrogenase
B2B01_RS16655	ENOG4105T95	Thiol disulfide interChange protein
B2B01_RS16660	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
B2B01_RS16665	ENOG4105CA3	membrane-bound lytic murein transglycosylase
B2B01_RS16670	ENOG4105NWN	ApaG protein
B2B01_RS16680	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
B2B01_RS16690	ENOG4108UPT	UPF0178 protein
B2B01_RS16700	ENOG4105EK3	May be involved in the control of utilization of gamma- aminobutyric acid (By similarity)
B2B01_RS16705	ENOG4107RSM	transcriptional regulator
B2B01_RS16715	ENOG4105C01	Dihydroxy-acid dehydratase
B2B01_RS16725	ENOG4107R3E	Citrate transporter
B2B01_RS16730	ENOG4105CSR	polyphosphate kinase 2
B2B01_RS16775	ENOG4105EJC	lysr family transcriptional regulator
B2B01_RS16780	ENOG4107EFR	Flavocytochrome c
B2B01_RS16795	ENOG4105CHR	reductase
B2B01_RS16800	ENOG4107EFR	Flavocytochrome c
B2B01_RS16820	ENOG4105C10	Electron transfer flavoprotein
B2B01_RS16830	ENOG4107EFR	Flavocytochrome c
B2B01_RS16835	ENOG4105BZJ	Electron transfer flavoprotein
B2B01_RS16840	ENOG4105C10	Electron transfer flavoprotein
B2B01_RS16865	ENOG4105F7P	transcriptional regulator AsnC family
B2B01_RS16875	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
B2B01_RS16880	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
B2B01_RS16885	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
B2B01_RS16905	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
B2B01_RS16910	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
B2B01_RS16925	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
B2B01_RS16930	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2B01_RS16945	ENOG4105C4W	S-formylglutathione hydrolase
B2B01_RS16950	ENOG4107QPD	alcohol dehydrogenase
B2B01_RS17000	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
B2B01_RS17005	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
B2B01_RS17010	ENOG4105E7W	lamb ycsf family protein
B2B01_RS17015	ENOG4105DUM	transcriptional regulator, lysR family
B2B01_RS17020	ENOG4105EIF	outer membrane protein W
B2B01_RS17025	ENOG4105DHJ	ABC, transporter
B2B01_RS17030	ENOG4105CY3	ABC transporter, permease
B2B01_RS17035	ENOG4107PE3	Mammalian cell entry related domain protein
B2B01_RS17050	ENOG4105DA5	(ABC) transporter
B2B01_RS17055	ENOG4105E3A	(ABC) transporter
B2B01_RS17065	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
B2B01_RS17070	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
B2B01_RS17075	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
B2B01_RS17080	ENOG4105CIH	Imidazole acetol-phosphate transaminase
B2B01_RS17085	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
B2B01_RS17095	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
B2B01_RS17100	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
B2B01_RS17105	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
B2B01_RS17110	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
B2B01_RS17115	ENOG4107YU2	histidine triad (hIT) protein
B2B01_RS17120	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
B2B01_RS17125	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
B2B01_RS17135	ENOG4105C0H	protease
B2B01_RS17140	ENOG4107QNR	UPF0135 protein
B2B01_RS17145	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
B2B01_RS17150	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B2B01_RS17155	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
B2B01_RS17160	ENOG4105EIX	cytochrome c1
B2B01_RS17165	ENOG4107MKT	Stringent starvation protein a
B2B01_RS17170	ENOG4105KB2	stringent starvation protein b
B2B01_RS17190	ENOG4105KD1	integral membrane protein
B2B01_RS17195	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
B2B01_RS17205	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS17210	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS17220	ENOG4105HA9	of methanol dehydrogenase type
B2B01_RS17230	ENOG4105C1J	atp-dependent rna helicase
B2B01_RS17235	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2B01_RS17240	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
B2B01_RS17250	ENOG4108UQY	Iron-storage protein
B2B01_RS17260	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
B2B01_RS17270	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
B2B01_RS17275	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
B2B01_RS17280	ENOG4105ETE	Transcriptional regulator (LacI family
B2B01_RS17295	ENOG4105E0C	molybdate abc transporter
B2B01_RS17300	ENOG4108IJ6	ABC transporter
B2B01_RS17305	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
B2B01_RS17320	ENOG4105C75	arginyL-tRNA synthetase
B2B01_RS17330	ENOG4108Z33	Thiol disulfide Interchange Protein
B2B01_RS17335	ENOG4105CXC	rtn protein
B2B01_RS17345	ENOG410829K	Lysine exporter protein (Lyse ygga)
B2B01_RS17360	ENOG4105C1G	acyl-Coa dehydrogenase
B2B01_RS17365	ENOG4105CHU	acetyl-coa acetyltransferase
B2B01_RS17370	ENOG4107QX3	carboxylase
B2B01_RS17385	ENOG4105C8Y	Acetylornithine aminotransferase
B2B01_RS17395	ENOG4105X58	receptor
B2B01_RS17400	ENOG4108RPN	Protein smg homolog
B2B01_RS17405	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
B2B01_RS17415	ENOG4105C9U	ATP-dependent DNA helicase RecQ
B2B01_RS17420	ENOG4105D2X	ABC transporter substrate-binding protein
B2B01_RS17430	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
B2B01_RS17435	ENOG4105CHR	reductase
B2B01_RS17440	ENOG4105C26	Dehydrogenase
B2B01_RS17450	ENOG4105C7K	acetolactate synthase
B2B01_RS17455	ENOG4108YXU	transcriptional regulator AsnC family
B2B01_RS17460	ENOG4105FFC	UPF0187 protein
B2B01_RS17485	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
B2B01_RS17490	ENOG4107TFB	basic membrane
B2B01_RS17495	ENOG4108JQ9	ABC transporter
B2B01_RS17500	ENOG4105UIB	(ABC) transporter
B2B01_RS17510	ENOG4105DZC	cytosine deaminase
B2B01_RS17525	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
B2B01_RS17530	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
B2B01_RS17540	ENOG4105C7W	Xanthine dehydrogenase
B2B01_RS17555	ENOG4105E0Y	RtcB Protein
B2B01_RS17560	ENOG4105CYB	regulatoR
B2B01_RS17565	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
B2B01_RS17570	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
B2B01_RS17575	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
B2B01_RS17585	ENOG4105VG0	50S ribosomal protein l34
B2B01_RS17590	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
B2B01_RS17595	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
B2B01_RS17600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
B2B01_RS17605	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
B2B01_RS17610	ENOG4105CH2	amidohydrolase
B2B01_RS17615	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
B2B01_RS17630	ENOG4105C6K	Malic enzyme
B2B01_RS17645	ENOG4105CHM	Aminotransferase