locus-tag	class	description
C0J07_RS00005	COG0445	tRNA wobble uridine modification
C0J07_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
C0J07_RS00015	COG1192	Involved in chromosome partitioning
C0J07_RS00020	COG1475	DNA binding
C0J07_RS00025	COG0252	asparaginase activity
C0J07_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0J07_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0J07_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C0J07_RS00070	COG0081	regulation of translation
C0J07_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0J07_RS00080	COG0222	ribosome binding
C0J07_RS00085	COG0085	RNA polymerase activity
C0J07_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C0J07_RS00120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0J07_RS00125	COG0049	tRNA binding
C0J07_RS00130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C0J07_RS00135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0J07_RS00140	COG0051	transcription antitermination factor activity, RNA binding
C0J07_RS00145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C0J07_RS00150	COG0088	Forms part of the polypeptide exit tunnel
C0J07_RS00155	COG0089	rRNA binding
C0J07_RS00160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0J07_RS00165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C0J07_RS00170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C0J07_RS00175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C0J07_RS00180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0J07_RS00185	COG0255	Belongs to the universal ribosomal protein uL29 family
C0J07_RS00190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C0J07_RS00200	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0J07_RS00205	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS00240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C0J07_RS00245	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C0J07_RS00250	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C0J07_RS00255	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0J07_RS00260	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C0J07_RS00265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C0J07_RS00270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C0J07_RS00275	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0J07_RS00280	COG1841	ribosomal large subunit assembly
C0J07_RS00285	COG0200	Binds to the 23S rRNA
C0J07_RS00290	COG0201	protein transport
C0J07_RS00295	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0J07_RS00300	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0J07_RS00305	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0J07_RS00310	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0J07_RS00315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C0J07_RS00320	COG0202	RNA polymerase activity
C0J07_RS00325	COG0203	ribosomal protein L17
C0J07_RS00335	COG1324	tolerance protein
C0J07_RS00340	COG4232	protein-disulfide reductase activity
C0J07_RS00350	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C0J07_RS00360	COG1333	cytochrome c biogenesis protein
C0J07_RS00365	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0J07_RS00380	COG1965	Belongs to the frataxin family
C0J07_RS00390	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C0J07_RS00395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C0J07_RS00400	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C0J07_RS00420	COG2814	Major facilitator Superfamily
C0J07_RS00425	COG0629	single-stranded DNA binding
C0J07_RS00475	COG1086	Polysaccharide biosynthesis protein
C0J07_RS00485	COG0438	transferase activity, transferring glycosyl groups
C0J07_RS00490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0J07_RS00495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0J07_RS00530	COG1840	ABC-type Fe3 transport system, periplasmic component
C0J07_RS00535	COG1175	transmembrane transport
C0J07_RS00540	COG3842	ATPase activity
C0J07_RS00550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C0J07_RS00560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0J07_RS00565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS00570	COG1956	GAF domain-containing protein
C0J07_RS00575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0J07_RS00600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0J07_RS00605	COG3568	Endonuclease Exonuclease Phosphatase
C0J07_RS00620	COG2814	Major facilitator Superfamily
C0J07_RS00630	COG3064	Membrane
C0J07_RS00630	COG3210	domain, Protein
C0J07_RS00630	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS00650	COG0859	PFAM glycosyl transferase family 9
C0J07_RS00660	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
C0J07_RS00670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0J07_RS00675	COG1127	ABC transporter
C0J07_RS00695	COG1686	Belongs to the peptidase S11 family
C0J07_RS00705	COG2921	Belongs to the UPF0250 family
C0J07_RS00710	COG0321	lipoyl(octanoyl) transferase activity
C0J07_RS00715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C0J07_RS00720	COG2096	Adenosyltransferase
C0J07_RS00730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C0J07_RS00735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C0J07_RS00745	COG0523	cobalamin synthesis protein
C0J07_RS00750	COG0735	belongs to the Fur family
C0J07_RS00760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0J07_RS00765	COG0803	Belongs to the bacterial solute-binding protein 9 family
C0J07_RS00785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0J07_RS00795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C0J07_RS00800	COG1560	Kdo2-lipid A biosynthetic process
C0J07_RS00810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C0J07_RS00830	COG1950	PFAM Membrane protein of
C0J07_RS00835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C0J07_RS00860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0J07_RS00870	COG0617	tRNA 3'-terminal CCA addition
C0J07_RS00880	COG0513	Belongs to the DEAD box helicase family
C0J07_RS00885	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C0J07_RS00890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0J07_RS00985	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS00990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0J07_RS00995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS01000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS01015	COG0758	DNA mediated transformation
C0J07_RS01020	COG2197	response regulator
C0J07_RS01025	COG1522	sequence-specific DNA binding
C0J07_RS01035	COG0242	peptide deformylase activity
C0J07_RS01040	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C0J07_RS01050	COG0546	phosphoglycolate phosphatase activity
C0J07_RS01060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0J07_RS01065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0J07_RS01100	COG2072	flavoprotein involved in K transport
C0J07_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0J07_RS01110	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS01115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0J07_RS01125	COG0583	DNA-binding transcription factor activity
C0J07_RS01130	COG2188	Transcriptional regulator
C0J07_RS01155	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS01160	COG1280	lysine exporter protein (LysE YggA)
C0J07_RS01165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0J07_RS01165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0J07_RS01180	COG2204	response regulator
C0J07_RS01185	COG0569	domain protein
C0J07_RS01195	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
C0J07_RS01200	COG2226	methyltransferase
C0J07_RS01205	COG1040	competence protein
C0J07_RS01215	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS01220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C0J07_RS01225	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C0J07_RS01230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0J07_RS01240	COG0588	phosphoglycerate mutase activity
C0J07_RS01245	COG4942	peptidase
C0J07_RS01250	COG0793	Belongs to the peptidase S41A family
C0J07_RS01255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0J07_RS01260	COG2186	Transcriptional regulator
C0J07_RS01270	COG0861	Integral membrane protein TerC family
C0J07_RS01275	COG0583	DNA-binding transcription factor activity
C0J07_RS01280	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C0J07_RS01285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0J07_RS01285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0J07_RS01305	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C0J07_RS01310	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C0J07_RS01315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C0J07_RS01320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C0J07_RS01325	COG0142	geranyltranstransferase activity
C0J07_RS01345	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS01350	COG4689	acetoacetate decarboxylase
C0J07_RS01410	COG1301	dicarboxylic acid transport
C0J07_RS01450	COG0154	amidase activity
C0J07_RS01455	COG0683	leucine binding
C0J07_RS01460	COG0583	DNA-binding transcription factor activity
C0J07_RS01515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0J07_RS01520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C0J07_RS01525	COG2890	protein-(glutamine-N5) methyltransferase activity
C0J07_RS01530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0J07_RS01550	COG0288	reversible hydration of carbon dioxide
C0J07_RS01560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0J07_RS01570	COG4829	muconolactone delta-isomerase
C0J07_RS01575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C0J07_RS01590	COG2031	fatty acid transporter
C0J07_RS01595	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0J07_RS01600	COG3539	Fimbrial protein
C0J07_RS01605	COG3539	Fimbrial protein
C0J07_RS01610	COG3539	Fimbrial protein
C0J07_RS01615	COG3539	Fimbrial protein
C0J07_RS01620	COG0129	dihydroxy-acid dehydratase activity
C0J07_RS01630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C0J07_RS01635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C0J07_RS01645	COG0673	inositol 2-dehydrogenase activity
C0J07_RS01650	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
C0J07_RS01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0J07_RS01670	COG0583	DNA-binding transcription factor activity
C0J07_RS01675	COG0628	permease
C0J07_RS01680	COG5285	phytanoyl-CoA dioxygenase
C0J07_RS01685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0J07_RS01770	COG0531	amino acid
C0J07_RS01775	COG1113	amino acid transport
C0J07_RS01780	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
C0J07_RS01785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C0J07_RS01795	COG3040	lipid binding
C0J07_RS01805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C0J07_RS01810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C0J07_RS01820	COG3171	Protein conserved in bacteria
C0J07_RS01875	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0J07_RS01910	COG2233	PERMEase
C0J07_RS01915	COG0326	Molecular chaperone. Has ATPase activity
C0J07_RS01920	COG0625	glutathione transferase activity
C0J07_RS01930	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0J07_RS01935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C0J07_RS01950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C0J07_RS01970	COG2423	ornithine cyclodeaminase activity
C0J07_RS01980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0J07_RS01990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0J07_RS02000	COG0010	Belongs to the arginase family
C0J07_RS02025	COG2194	sulfuric ester hydrolase activity
C0J07_RS02045	COG1054	Belongs to the UPF0176 family
C0J07_RS02050	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J07_RS02050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J07_RS02060	COG0489	protein tyrosine kinase activity
C0J07_RS02075	COG0717	Belongs to the dCTP deaminase family
C0J07_RS02095	COG2081	HI0933 family
C0J07_RS02100	COG1609	Transcriptional regulator
C0J07_RS02105	COG0683	leucine binding
C0J07_RS02110	COG0559	Belongs to the binding-protein-dependent transport system permease family
C0J07_RS02135	COG0371	Dehydrogenase
C0J07_RS02145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C0J07_RS02150	COG0509	glycine decarboxylation via glycine cleavage system
C0J07_RS02155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0J07_RS02155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0J07_RS02180	COG4172	Belongs to the ABC transporter superfamily
C0J07_RS02185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS02190	COG0601	transmembrane transport
C0J07_RS02195	COG0747	negative chemotaxis
C0J07_RS02210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0J07_RS02215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS02225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C0J07_RS02235	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
C0J07_RS02240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0J07_RS02245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C0J07_RS02260	COG0438	transferase activity, transferring glycosyl groups
C0J07_RS02275	COG0438	transferase activity, transferring glycosyl groups
C0J07_RS02285	COG0166	Belongs to the GPI family
C0J07_RS02300	COG0277	FAD linked oxidase domain protein
C0J07_RS02305	COG0745	RESPONSE REGULATOR receiver
C0J07_RS02310	COG5002	protein histidine kinase activity
C0J07_RS02310	COG5000	phosphorelay sensor kinase activity
C0J07_RS02315	COG2186	Transcriptional regulator
C0J07_RS02320	COG1368	sulfuric ester hydrolase activity
C0J07_RS02330	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C0J07_RS02345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0J07_RS02355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C0J07_RS02365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C0J07_RS02370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C0J07_RS02380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0J07_RS02385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C0J07_RS02390	COG0193	aminoacyl-tRNA hydrolase activity
C0J07_RS02400	COG0012	GTP binding
C0J07_RS02415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C0J07_RS02425	COG0732	type I restriction modification DNA specificity domain
C0J07_RS02430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C0J07_RS02470	COG0387	Pfam Sodium calcium exchanger
C0J07_RS02500	COG3135	benzoate transporter
C0J07_RS02505	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0J07_RS02510	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C0J07_RS02515	COG0742	ribosomal rna small subunit methyltransferase
C0J07_RS02545	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C0J07_RS02550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0J07_RS02555	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C0J07_RS02560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0J07_RS02570	COG0284	orotidine-5'-phosphate decarboxylase activity
C0J07_RS02575	COG1252	NADH dehydrogenase
C0J07_RS02580	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0J07_RS02585	COG1295	ribonuclease BN
C0J07_RS02590	COG0459	protein refolding
C0J07_RS02595	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0J07_RS02635	COG2814	Major facilitator Superfamily
C0J07_RS02650	COG1393	Belongs to the ArsC family
C0J07_RS02655	COG0431	NADPH-dependent FMN reductase
C0J07_RS02665	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS02670	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0J07_RS02710	COG4569	acetaldehyde dehydrogenase (acetylating) activity
C0J07_RS02715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0J07_RS02725	COG0477	Major facilitator Superfamily
C0J07_RS02755	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS02770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0J07_RS02785	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0J07_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS02830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C0J07_RS02835	COG1802	Transcriptional regulator
C0J07_RS02840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0J07_RS02845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0J07_RS02850	COG1335	isochorismatase
C0J07_RS02855	COG0523	cobalamin synthesis protein
C0J07_RS02935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0J07_RS02940	COG1116	anion transmembrane transporter activity
C0J07_RS02965	COG3395	kinase activity
C0J07_RS02970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0J07_RS02985	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0J07_RS03010	COG2146	nitrite reductase [NAD(P)H] activity
C0J07_RS03025	COG3971	2-oxopent-4-enoate hydratase activity
C0J07_RS03060	COG0513	Belongs to the DEAD box helicase family
C0J07_RS03070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0J07_RS03075	COG0583	DNA-binding transcription factor activity
C0J07_RS03095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS03100	COG1126	abc transporter atp-binding protein
C0J07_RS03105	COG0765	amino acid transport
C0J07_RS03110	COG0765	amino acid transport
C0J07_RS03115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0J07_RS03140	COG1522	sequence-specific DNA binding
C0J07_RS03145	COG4106	trans-aconitate 2-methyltransferase activity
C0J07_RS03150	COG0667	Aldo Keto reductase
C0J07_RS03160	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0J07_RS03170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0J07_RS03180	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C0J07_RS03185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0J07_RS03190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C0J07_RS03195	COG1929	Belongs to the glycerate kinase type-1 family
C0J07_RS03205	COG0700	Nucleoside recognition
C0J07_RS03210	COG0242	peptide deformylase activity
C0J07_RS03230	COG0583	DNA-binding transcription factor activity
C0J07_RS03240	COG0204	Acyl-transferase
C0J07_RS03245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C0J07_RS03250	COG0751	glycine-tRNA ligase activity
C0J07_RS03255	COG0752	glycyl-tRNA synthetase alpha subunit
C0J07_RS03260	COG1024	Enoyl-CoA hydratase
C0J07_RS03270	COG3064	Membrane
C0J07_RS03270	COG3210	domain, Protein
C0J07_RS03270	COG3210	domain, Protein
C0J07_RS03270	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS03270	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS03270	COG3064	Membrane
C0J07_RS03275	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
C0J07_RS03300	COG1335	isochorismatase
C0J07_RS03310	COG0617	tRNA 3'-terminal CCA addition
C0J07_RS03320	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0J07_RS03325	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0J07_RS03330	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C0J07_RS03335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C0J07_RS03340	COG0586	Pfam SNARE associated Golgi protein
C0J07_RS03350	COG0028	Belongs to the TPP enzyme family
C0J07_RS03355	COG0579	oxidoreductase
C0J07_RS03370	COG0860	N-Acetylmuramoyl-L-alanine amidase
C0J07_RS03375	COG0802	atpase or kinase
C0J07_RS03380	COG0114	fumarate hydratase activity
C0J07_RS03390	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS03410	COG1116	anion transmembrane transporter activity
C0J07_RS03415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0J07_RS03440	COG0625	glutathione transferase activity
C0J07_RS03445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0J07_RS03455	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0J07_RS03465	COG2885	chlorophyll binding
C0J07_RS03480	COG0840	transmembrane signaling receptor activity
C0J07_RS03490	COG5265	(ABC) transporter
C0J07_RS03500	COG0833	amino acid
C0J07_RS03530	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C0J07_RS03540	COG1408	metallophosphoesterase
C0J07_RS03555	COG2814	Major facilitator Superfamily
C0J07_RS03560	COG2610	gluconate transmembrane transporter activity
C0J07_RS03565	COG0625	glutathione transferase activity
C0J07_RS03570	COG2070	2-Nitropropane dioxygenase
C0J07_RS03580	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C0J07_RS03605	COG0783	Belongs to the Dps family
C0J07_RS03625	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
C0J07_RS03630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0J07_RS03635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0J07_RS03640	COG1845	cytochrome c oxidase, subunit III
C0J07_RS03645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0J07_RS03665	COG1666	GTP binding
C0J07_RS03685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C0J07_RS03695	COG1136	(ABC) transporter
C0J07_RS03745	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS03750	COG5006	permease, DMT superfamily
C0J07_RS03765	COG2264	protein methyltransferase activity
C0J07_RS03775	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C0J07_RS03780	COG3383	formate dehydrogenase (NAD+) activity
C0J07_RS03800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0J07_RS03810	COG0303	'Molybdopterin
C0J07_RS03815	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0J07_RS03820	COG0314	molybdopterin synthase activity
C0J07_RS03825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C0J07_RS03830	COG0315	cyclic pyranopterin monophosphate synthase activity
C0J07_RS03840	COG0678	peroxiredoxin activity
C0J07_RS03850	COG0697	spore germination
C0J07_RS03855	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C0J07_RS03905	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C0J07_RS03910	COG1702	phosphate starvation-inducible protein PhoH
C0J07_RS03915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C0J07_RS03920	COG4535	Mg2 and Co2 transporter CorC
C0J07_RS03925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C0J07_RS03930	COG0667	Aldo Keto reductase
C0J07_RS03950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0J07_RS03955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0J07_RS03960	COG1862	Preprotein translocase
C0J07_RS03965	COG0343	queuine tRNA-ribosyltransferase activity
C0J07_RS03970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C0J07_RS03975	COG2027	D-alanyl-D-alanine carboxypeptidase
C0J07_RS03980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C0J07_RS03985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0J07_RS03985	COG1648	precorrin-2 dehydrogenase activity
C0J07_RS04015	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C0J07_RS04030	COG0436	Aminotransferase
C0J07_RS04040	COG0280	phosphate acetyltransferase
C0J07_RS04040	COG0281	malic enzyme
C0J07_RS04055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0J07_RS04060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0J07_RS04065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0J07_RS04070	COG0126	phosphoglycerate kinase activity
C0J07_RS04080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C0J07_RS04085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0J07_RS04100	COG0625	glutathione transferase activity
C0J07_RS04130	COG0306	phosphate transporter
C0J07_RS04135	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0J07_RS04145	COG0739	heme binding
C0J07_RS04155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0J07_RS04165	COG0697	spore germination
C0J07_RS04180	COG0456	acetyltransferase
C0J07_RS04185	COG1301	dicarboxylic acid transport
C0J07_RS04195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0J07_RS04200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C0J07_RS04205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C0J07_RS04210	COG0009	L-threonylcarbamoyladenylate synthase
C0J07_RS04215	COG1414	Transcriptional regulator
C0J07_RS04225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS04230	COG0765	amino acid transport
C0J07_RS04235	COG1126	abc transporter atp-binding protein
C0J07_RS04240	COG0028	Belongs to the TPP enzyme family
C0J07_RS04250	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS04255	COG0028	Belongs to the TPP enzyme family
C0J07_RS04260	COG0583	DNA-binding transcription factor activity
C0J07_RS04265	COG4974	Belongs to the 'phage' integrase family
C0J07_RS04270	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0J07_RS04285	COG1686	Belongs to the peptidase S11 family
C0J07_RS04305	COG1074	ATP-dependent DNA helicase activity
C0J07_RS04315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C0J07_RS04320	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0J07_RS04325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C0J07_RS04335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0J07_RS04340	COG0505	Belongs to the CarA family
C0J07_RS04345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0J07_RS04350	COG0406	alpha-ribazole phosphatase activity
C0J07_RS04360	COG3842	ATPase activity
C0J07_RS04380	COG2233	PERMEase
C0J07_RS04385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C0J07_RS04395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C0J07_RS04400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0J07_RS04410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0J07_RS04430	COG3064	Membrane
C0J07_RS04430	COG3210	domain, Protein
C0J07_RS04430	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS04435	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS04435	COG3210	domain, Protein
C0J07_RS04435	COG3064	Membrane
C0J07_RS04455	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0J07_RS04480	COG2188	Transcriptional regulator
C0J07_RS04510	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0J07_RS04515	COG0066	3-isopropylmalate dehydratase activity
C0J07_RS04535	COG3976	FMN-binding domain protein
C0J07_RS04535	COG1053	succinate dehydrogenase
C0J07_RS04550	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C0J07_RS04555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS04575	COG1473	amidohydrolase
C0J07_RS04585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0J07_RS04600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0J07_RS04625	COG1024	Enoyl-CoA hydratase
C0J07_RS04635	COG2267	carboxylic ester hydrolase activity
C0J07_RS04645	COG0318	PFAM AMP-dependent synthetase and ligase
C0J07_RS04695	COG1271	oxidase subunit
C0J07_RS04700	COG1294	oxidase, subunit
C0J07_RS04720	COG0154	amidase activity
C0J07_RS04725	COG4608	Belongs to the ABC transporter superfamily
C0J07_RS04730	COG0444	Belongs to the ABC transporter superfamily
C0J07_RS04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS04740	COG0601	transmembrane transport
C0J07_RS04745	COG4166	transmembrane transport
C0J07_RS04755	COG3706	GGDEF domain
C0J07_RS04775	COG0025	NhaP-type Na H and K H
C0J07_RS04805	COG1228	amidohydrolase
C0J07_RS04820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0J07_RS04825	COG0500	methyltransferase
C0J07_RS04830	COG0840	transmembrane signaling receptor activity
C0J07_RS04855	COG2201	protein-glutamate methylesterase activity
C0J07_RS04860	COG2203	Gaf domain
C0J07_RS04860	COG4251	negative regulation of phosphorylation
C0J07_RS04860	COG3706	GGDEF domain
C0J07_RS04860	COG5001	Diguanylate cyclase
C0J07_RS04865	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
C0J07_RS04870	COG4166	transmembrane transport
C0J07_RS04890	COG0583	DNA-binding transcription factor activity
C0J07_RS04900	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS04915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0J07_RS04940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C0J07_RS04945	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0J07_RS04950	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0J07_RS04955	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0J07_RS04960	COG0649	NAD binding
C0J07_RS04965	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
C0J07_RS04975	COG1034	ATP synthesis coupled electron transport
C0J07_RS04980	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C0J07_RS04985	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0J07_RS04995	COG0713	ATP synthesis coupled electron transport
C0J07_RS05010	COG1007	ATP synthesis coupled electron transport
C0J07_RS05030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C0J07_RS05035	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C0J07_RS05040	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0J07_RS05045	COG0560	Phosphoserine phosphatase
C0J07_RS05050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0J07_RS05055	COG0450	alkyl hydroperoxide reductase
C0J07_RS05070	COG1214	PFAM Peptidase M22, glycoprotease
C0J07_RS05075	COG1573	uracil-dna glycosylase
C0J07_RS05080	COG0477	Major facilitator Superfamily
C0J07_RS05085	COG1196	nuclear chromosome segregation
C0J07_RS05095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0J07_RS05100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0J07_RS05110	COG2917	probably involved in intracellular septation
C0J07_RS05115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C0J07_RS05120	COG1122	ATPase activity
C0J07_RS05125	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C0J07_RS05130	COG1268	BioY protein
C0J07_RS05190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0J07_RS05195	COG2878	Part of a membrane complex involved in electron transport
C0J07_RS05215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C0J07_RS05220	COG0251	oxidation-reduction process
C0J07_RS05230	COG3228	Belongs to the MtfA family
C0J07_RS05235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0J07_RS05250	COG0159	tryptophan synthase activity
C0J07_RS05255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C0J07_RS05260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C0J07_RS05275	COG1530	ribonuclease E activity
C0J07_RS05280	COG0564	pseudouridine synthase activity
C0J07_RS05285	COG0546	phosphoglycolate phosphatase activity
C0J07_RS05290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C0J07_RS05295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C0J07_RS05300	COG3023	N-Acetylmuramoyl-L-alanine amidase
C0J07_RS05310	COG0424	maF-like protein
C0J07_RS05315	COG1399	metal-binding, possibly nucleic acid-binding protein
C0J07_RS05320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C0J07_RS05330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0J07_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS05345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0J07_RS05350	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0J07_RS05375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0J07_RS05380	COG0481	GTPase activity
C0J07_RS05385	COG0681	Belongs to the peptidase S26 family
C0J07_RS05390	COG0571	ribonuclease III activity
C0J07_RS05395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C0J07_RS05400	COG1381	Involved in DNA repair and RecF pathway recombination
C0J07_RS05420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0J07_RS05430	COG0583	DNA-binding transcription factor activity
C0J07_RS05445	COG0583	DNA-binding transcription factor activity
C0J07_RS05455	COG0791	NLP P60 protein
C0J07_RS05460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0J07_RS05465	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C0J07_RS05475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0J07_RS05480	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C0J07_RS05515	COG1446	asparaginase
C0J07_RS05520	COG4172	Belongs to the ABC transporter superfamily
C0J07_RS05525	COG0747	negative chemotaxis
C0J07_RS05530	COG0601	transmembrane transport
C0J07_RS05535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS05555	COG0504	CTP synthase activity
C0J07_RS05560	COG0148	phosphopyruvate hydratase activity
C0J07_RS05575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0J07_RS05585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0J07_RS05600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0J07_RS05615	COG1981	membrane
C0J07_RS05630	COG0039	L-malate dehydrogenase activity
C0J07_RS05635	COG2188	Transcriptional regulator
C0J07_RS05640	COG2009	succinate dehydrogenase
C0J07_RS05645	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C0J07_RS05650	COG1053	succinate dehydrogenase
C0J07_RS05655	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0J07_RS05660	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C0J07_RS05665	COG0372	Belongs to the citrate synthase family
C0J07_RS05670	COG3706	GGDEF domain
C0J07_RS05675	COG0583	DNA-binding transcription factor activity
C0J07_RS05680	COG3842	ATPase activity
C0J07_RS05690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0J07_RS05695	COG1840	ABC-type Fe3 transport system, periplasmic component
C0J07_RS05700	COG2022	thiamine diphosphate biosynthetic process
C0J07_RS05700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS05710	COG3128	pkhd-type hydroxylase
C0J07_RS05715	COG4774	siderophore transport
C0J07_RS05730	COG0280	phosphate acetyltransferase
C0J07_RS05730	COG0281	malic enzyme
C0J07_RS05740	COG1297	OPT oligopeptide transporter protein
C0J07_RS05745	COG0567	Dehydrogenase, E1 component
C0J07_RS05750	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0J07_RS05755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0J07_RS05760	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C0J07_RS05765	COG1595	DNA-templated transcription, initiation
C0J07_RS05770	COG3712	iron ion homeostasis
C0J07_RS05775	COG4774	siderophore transport
C0J07_RS05800	COG1199	ATP-dependent helicase activity
C0J07_RS05805	COG2183	response to ionizing radiation
C0J07_RS05820	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS05820	COG3210	domain, Protein
C0J07_RS05820	COG3064	Membrane
C0J07_RS05830	COG0564	pseudouridine synthase activity
C0J07_RS05840	COG3243	poly(R)-hydroxyalkanoic acid synthase
C0J07_RS05845	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS05850	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
C0J07_RS05865	COG0672	)-iron permease
C0J07_RS05890	COG3237	CsbD-like
C0J07_RS05895	COG0189	ligase activity
C0J07_RS05895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C0J07_RS05900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C0J07_RS05900	COG0189	ligase activity
C0J07_RS05905	COG1132	(ABC) transporter
C0J07_RS05915	COG0297	glycogen (starch) synthase activity
C0J07_RS05920	COG2833	Protein of unknown function (DUF455)
C0J07_RS05925	COG2951	lytic endotransglycosylase activity
C0J07_RS05940	COG0586	Pfam SNARE associated Golgi protein
C0J07_RS05955	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C0J07_RS05960	COG0463	Glycosyl transferase, family 2
C0J07_RS05970	COG3958	Transketolase
C0J07_RS05975	COG3959	Transketolase, thiamine diphosphate binding domain
C0J07_RS06000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0J07_RS06020	COG3971	2-oxopent-4-enoate hydratase activity
C0J07_RS06035	COG0179	Fumarylacetoacetate (FAA) hydrolase
C0J07_RS06040	COG1012	belongs to the aldehyde dehydrogenase family
C0J07_RS06060	COG0154	amidase activity
C0J07_RS06115	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0J07_RS06130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0J07_RS06140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0J07_RS06150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C0J07_RS06155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C0J07_RS06175	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C0J07_RS06180	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C0J07_RS06185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0J07_RS06200	COG2951	lytic endotransglycosylase activity
C0J07_RS06220	COG2985	domain, Protein
C0J07_RS06225	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS06230	COG0450	alkyl hydroperoxide reductase
C0J07_RS06255	COG0335	large ribosomal subunit rRNA binding
C0J07_RS06265	COG3622	Belongs to the hyi family
C0J07_RS06270	COG1162	GTPase activity
C0J07_RS06275	COG0501	Belongs to the peptidase M48B family
C0J07_RS06280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C0J07_RS06285	COG3327	negative regulation of DNA-templated transcription, initiation
C0J07_RS06290	COG3396	Phenylacetate-CoA oxygenase
C0J07_RS06295	COG3460	Phenylacetate-CoA oxygenase
C0J07_RS06300	COG3396	Phenylacetate-CoA oxygenase
C0J07_RS06305	COG2151	metal-sulfur cluster biosynthetic enzyme
C0J07_RS06310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0J07_RS06320	COG1024	Enoyl-CoA hydratase
C0J07_RS06325	COG2050	protein possibly involved in aromatic compounds catabolism
C0J07_RS06345	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0J07_RS06350	COG2197	response regulator
C0J07_RS06355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C0J07_RS06360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0J07_RS06375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0J07_RS06380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0J07_RS06385	COG1914	H( )-stimulated, divalent metal cation uptake system
C0J07_RS06390	COG2423	ornithine cyclodeaminase activity
C0J07_RS06400	COG0756	dUTP diphosphatase activity
C0J07_RS06425	COG1522	sequence-specific DNA binding
C0J07_RS06435	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0J07_RS06440	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C0J07_RS06445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C0J07_RS06450	COG0196	riboflavin kinase activity
C0J07_RS06455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0J07_RS06460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0J07_RS06460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0J07_RS06475	COG0210	DNA helicase
C0J07_RS06480	COG0488	(ABC) transporter
C0J07_RS06485	COG2890	protein-(glutamine-N5) methyltransferase activity
C0J07_RS06490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0J07_RS06495	COG2171	N-acyltransferase activity
C0J07_RS06510	COG0582	viral genome integration into host DNA
C0J07_RS06540	COG3723	Recombinational DNA repair protein, rece pathway
C0J07_RS06545	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0J07_RS06660	COG4626	Terminase
C0J07_RS06660	COG1802	Transcriptional regulator
C0J07_RS06780	COG2944	sequence-specific DNA binding
C0J07_RS06810	COG1278	Cold shock
C0J07_RS06820	COG1278	Cold shock
C0J07_RS06830	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0J07_RS06835	COG0740	serine-type endopeptidase activity
C0J07_RS06840	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C0J07_RS06845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C0J07_RS06855	COG3135	benzoate transporter
C0J07_RS06860	COG2814	Major facilitator Superfamily
C0J07_RS06865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0J07_RS06875	COG0556	nucleotide-excision repair
C0J07_RS06880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0J07_RS06890	COG1104	cysteine desulfurase activity
C0J07_RS06895	COG0822	iron-sulfur transferase activity
C0J07_RS06905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C0J07_RS06910	COG0443	Heat shock 70 kDa protein
C0J07_RS06915	COG0633	Ferredoxin
C0J07_RS06920	COG2975	iron-sulfur cluster assembly
C0J07_RS06925	COG1803	Methylglyoxal synthase
C0J07_RS06935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C0J07_RS06940	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS06950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C0J07_RS06965	COG1136	(ABC) transporter
C0J07_RS06970	COG0084	hydrolase, TatD family'
C0J07_RS06985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C0J07_RS06985	COG2010	Cytochrome c
C0J07_RS06990	COG1335	isochorismatase
C0J07_RS06995	COG2309	aminopeptidase activity
C0J07_RS07000	COG0596	Alpha beta hydrolase
C0J07_RS07005	COG3473	Maleate cis-trans isomerase
C0J07_RS07015	COG2080	2 iron, 2 sulfur cluster binding
C0J07_RS07020	COG2010	Cytochrome c
C0J07_RS07020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C0J07_RS07025	COG0477	Major facilitator Superfamily
C0J07_RS07030	COG1846	Transcriptional regulator
C0J07_RS07040	COG2271	Major facilitator Superfamily
C0J07_RS07050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C0J07_RS07060	COG2200	EAL domain
C0J07_RS07070	COG0613	PHP domain protein
C0J07_RS07080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C0J07_RS07080	COG0047	phosphoribosylformylglycinamidine synthase activity
C0J07_RS07090	COG3064	Membrane
C0J07_RS07090	COG3064	Membrane
C0J07_RS07090	COG3210	domain, Protein
C0J07_RS07090	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS07090	COG3210	domain, Protein
C0J07_RS07090	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS07130	COG0747	negative chemotaxis
C0J07_RS07135	COG4608	Belongs to the ABC transporter superfamily
C0J07_RS07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS07150	COG0601	transmembrane transport
C0J07_RS07155	COG2072	flavoprotein involved in K transport
C0J07_RS07175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0J07_RS07175	COG0519	Catalyzes the synthesis of GMP from XMP
C0J07_RS07220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C0J07_RS07230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C0J07_RS07235	COG2146	nitrite reductase [NAD(P)H] activity
C0J07_RS07240	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0J07_RS07250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C0J07_RS07255	COG1846	Transcriptional regulator
C0J07_RS07260	COG0477	Major facilitator Superfamily
C0J07_RS07265	COG3608	succinylglutamate desuccinylase aspartoacylase
C0J07_RS07265	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C0J07_RS07285	COG3046	protein related to deoxyribodipyrimidine photolyase
C0J07_RS07290	COG0415	Belongs to the DNA photolyase family
C0J07_RS07295	COG0322	excinuclease ABC activity
C0J07_RS07325	COG0302	gtp cyclohydrolase
C0J07_RS07330	COG0789	Transcriptional regulator
C0J07_RS07335	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0J07_RS07340	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C0J07_RS07350	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C0J07_RS07360	COG0596	Alpha beta hydrolase
C0J07_RS07370	COG2814	Major facilitator Superfamily
C0J07_RS07375	COG0640	Transcriptional regulator
C0J07_RS07380	COG0833	amino acid
C0J07_RS07385	COG2814	Major facilitator Superfamily
C0J07_RS07430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0J07_RS07455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
C0J07_RS07460	COG1136	(ABC) transporter
C0J07_RS07460	COG0577	efflux transmembrane transporter activity
C0J07_RS07465	COG0390	transport system, permease component
C0J07_RS07510	COG0165	Argininosuccinate lyase
C0J07_RS07515	COG0668	transmembrane transport
C0J07_RS07550	COG0583	DNA-binding transcription factor activity
C0J07_RS07560	COG0747	negative chemotaxis
C0J07_RS07565	COG0601	transmembrane transport
C0J07_RS07570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS07575	COG4172	Belongs to the ABC transporter superfamily
C0J07_RS07580	COG1280	lysine exporter protein (LysE YggA)
C0J07_RS07590	COG3161	chorismate lyase activity
C0J07_RS07595	COG1187	pseudouridine synthase activity
C0J07_RS07635	COG1999	signal sequence binding
C0J07_RS07645	COG0339	signal peptide processing
C0J07_RS07650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0J07_RS07655	COG4566	intracellular signal transduction
C0J07_RS07665	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C0J07_RS07670	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0J07_RS07675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0J07_RS07680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0J07_RS07680	COG4797	methyltransferase
C0J07_RS07715	COG0745	RESPONSE REGULATOR receiver
C0J07_RS07720	COG2198	Histidine kinase
C0J07_RS07720	COG0643	Histidine kinase
C0J07_RS07730	COG0840	transmembrane signaling receptor activity
C0J07_RS07735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0J07_RS07740	COG2201	protein-glutamate methylesterase activity
C0J07_RS07745	COG0745	RESPONSE REGULATOR receiver
C0J07_RS07750	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C0J07_RS07775	COG2747	anti-sigma28 factor FlgM
C0J07_RS07785	COG1815	bacterial-type flagellum-dependent cell motility
C0J07_RS07800	COG1749	Flagellar hook protein flgE
C0J07_RS07805	COG4787	bacterial-type flagellum-dependent cell motility
C0J07_RS07820	COG1706	bacterial-type flagellum-dependent cell motility
C0J07_RS07840	COG0840	transmembrane signaling receptor activity
C0J07_RS07845	COG0840	transmembrane signaling receptor activity
C0J07_RS07855	COG0840	transmembrane signaling receptor activity
C0J07_RS07860	COG0840	transmembrane signaling receptor activity
C0J07_RS07895	COG1580	Controls the rotational direction of flagella during chemotaxis
C0J07_RS07915	COG1317	bacterial-type flagellum organization
C0J07_RS07920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0J07_RS07925	COG1766	The M ring may be actively involved in energy transduction
C0J07_RS07930	COG1677	Flagellar hook-basal body complex protein FliE
C0J07_RS07940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C0J07_RS07960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C0J07_RS07970	COG0285	dihydrofolate synthase activity
C0J07_RS07980	COG1286	toxin biosynthetic process
C0J07_RS07990	COG5383	Protein conserved in bacteria
C0J07_RS08000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C0J07_RS08005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C0J07_RS08010	COG0024	Methionine aminopeptidase
C0J07_RS08015	COG0052	Belongs to the universal ribosomal protein uS2 family
C0J07_RS08020	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0J07_RS08025	COG0528	UMP kinase activity
C0J07_RS08030	COG0233	cytoplasmic translational termination
C0J07_RS08035	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C0J07_RS08040	COG0575	Belongs to the CDS family
C0J07_RS08045	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C0J07_RS08050	COG0750	zinc metalloprotease
C0J07_RS08055	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0J07_RS08060	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C0J07_RS08065	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0J07_RS08070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0J07_RS08080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0J07_RS08085	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0J07_RS08090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0J07_RS08100	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C0J07_RS08125	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C0J07_RS08130	COG2867	negative regulation of translational initiation
C0J07_RS08135	COG2914	Belongs to the UPF0125 (RnfH) family
C0J07_RS08140	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS08145	COG1024	Enoyl-CoA hydratase
C0J07_RS08145	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0J07_RS08165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0J07_RS08170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C0J07_RS08180	COG0084	hydrolase, TatD family'
C0J07_RS08220	COG3121	Chaperone
C0J07_RS08230	COG3539	Fimbrial protein
C0J07_RS08240	COG0833	amino acid
C0J07_RS08275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0J07_RS08300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0J07_RS08305	COG0456	acetyltransferase
C0J07_RS08315	COG2900	Belongs to the SlyX family
C0J07_RS08320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0J07_RS08335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0J07_RS08335	COG0519	Catalyzes the synthesis of GMP from XMP
C0J07_RS08340	COG0583	DNA-binding transcription factor activity
C0J07_RS08345	COG0477	Major facilitator Superfamily
C0J07_RS08365	COG3258	Cytochrome c
C0J07_RS08395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0J07_RS08400	COG1129	ABC transporter
C0J07_RS08400	COG0842	Transport permease protein
C0J07_RS08405	COG0842	Transport permease protein
C0J07_RS08415	COG2259	Doxx family
C0J07_RS08435	COG0154	amidase activity
C0J07_RS08440	COG0477	Major facilitator Superfamily
C0J07_RS08450	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C0J07_RS08470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C0J07_RS08485	COG0386	Belongs to the glutathione peroxidase family
C0J07_RS08495	COG0095	Lipoate-protein ligase
C0J07_RS08505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0J07_RS08510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS08515	COG0477	Major facilitator Superfamily
C0J07_RS08520	COG2391	methyltransferase activity
C0J07_RS08525	COG2897	thiosulfate sulfurtransferase activity
C0J07_RS08540	COG0431	NADPH-dependent FMN reductase
C0J07_RS08545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J07_RS08550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J07_RS08555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J07_RS08565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS08580	COG1695	Transcriptional regulator
C0J07_RS08590	COG2819	hydrolase of the alpha beta superfamily
C0J07_RS08640	COG1126	abc transporter atp-binding protein
C0J07_RS08645	COG0765	amino acid transport
C0J07_RS08650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS08660	COG2200	EAL domain
C0J07_RS08675	COG1253	flavin adenine dinucleotide binding
C0J07_RS08680	COG2203	Gaf domain
C0J07_RS08680	COG3706	GGDEF domain
C0J07_RS08680	COG5001	Diguanylate cyclase
C0J07_RS08680	COG4251	negative regulation of phosphorylation
C0J07_RS08685	COG2197	response regulator
C0J07_RS08690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS08690	COG2205	protein histidine kinase activity
C0J07_RS08700	COG2186	Transcriptional regulator
C0J07_RS08705	COG0028	Belongs to the TPP enzyme family
C0J07_RS08715	COG0688	phosphatidylethanolamine metabolic process
C0J07_RS08725	COG1464	Belongs to the NlpA lipoprotein family
C0J07_RS08740	COG2363	Small membrane protein
C0J07_RS08745	COG0697	spore germination
C0J07_RS08750	COG0625	glutathione transferase activity
C0J07_RS08755	COG1794	racemase activity, acting on amino acids and derivatives
C0J07_RS08775	COG0559	Belongs to the binding-protein-dependent transport system permease family
C0J07_RS08790	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0J07_RS08800	COG1653	transport
C0J07_RS08805	COG1175	transmembrane transport
C0J07_RS08810	COG0395	ABC-type sugar transport system, permease component
C0J07_RS08815	COG3842	ATPase activity
C0J07_RS08830	COG0783	Belongs to the Dps family
C0J07_RS08840	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
C0J07_RS08865	COG0625	glutathione transferase activity
C0J07_RS08885	COG2186	Transcriptional regulator
C0J07_RS08900	COG0583	DNA-binding transcription factor activity
C0J07_RS08905	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0J07_RS08920	COG1840	ABC-type Fe3 transport system, periplasmic component
C0J07_RS08930	COG3842	ATPase activity
C0J07_RS08935	COG1741	Belongs to the pirin family
C0J07_RS08940	COG1741	Belongs to the pirin family
C0J07_RS08945	COG0583	DNA-binding transcription factor activity
C0J07_RS08955	COG3852	Histidine kinase
C0J07_RS08960	COG0174	glutamine synthetase
C0J07_RS08965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0J07_RS08970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C0J07_RS08975	COG3300	MHYT domain
C0J07_RS08975	COG5001	Diguanylate cyclase
C0J07_RS08980	COG0840	transmembrane signaling receptor activity
C0J07_RS08990	COG1561	YicC-like family, N-terminal region
C0J07_RS08995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0J07_RS09010	COG0653	protein targeting
C0J07_RS09045	COG4585	Histidine kinase
C0J07_RS09060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0J07_RS09065	COG0791	NLP P60 protein
C0J07_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS09075	COG0194	GDP metabolic process
C0J07_RS09080	COG1758	RNA polymerase activity
C0J07_RS09085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0J07_RS09090	COG1126	abc transporter atp-binding protein
C0J07_RS09095	COG0765	amino acid transport
C0J07_RS09100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS09105	COG2831	hemolysin activation secretion protein
C0J07_RS09115	COG3188	usher protein
C0J07_RS09120	COG3121	Chaperone
C0J07_RS09125	COG3539	Fimbrial protein
C0J07_RS09130	COG3210	domain, Protein
C0J07_RS09130	COG3064	Membrane
C0J07_RS09130	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS09130	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS09130	COG3210	domain, Protein
C0J07_RS09130	COG3064	Membrane
C0J07_RS09135	COG4181	ATPase activity
C0J07_RS09145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0J07_RS09150	COG0584	glycerophosphoryl diester phosphodiesterase
C0J07_RS09155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C0J07_RS09165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0J07_RS09165	COG0678	peroxiredoxin activity
C0J07_RS09180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0J07_RS09200	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C0J07_RS09205	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C0J07_RS09210	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C0J07_RS09215	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C0J07_RS09220	COG2252	PERMEase
C0J07_RS09225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C0J07_RS09230	COG3118	belongs to the thioredoxin family
C0J07_RS09260	COG0488	(ABC) transporter
C0J07_RS09265	COG1619	proteins homologs of microcin C7 resistance protein MccF
C0J07_RS09285	COG1320	monovalent cation:proton antiporter activity
C0J07_RS09290	COG2212	antiporter activity
C0J07_RS09295	COG1863	multisubunit Na H antiporter MnhE subunit
C0J07_RS09300	COG0651	ATP synthesis coupled electron transport
C0J07_RS09305	COG1006	Multisubunit Na H antiporter MnhC subunit
C0J07_RS09310	COG2111	Na H antiporter
C0J07_RS09310	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C0J07_RS09325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS09345	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0J07_RS09355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C0J07_RS09360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0J07_RS09395	COG0602	queuosine metabolic process
C0J07_RS09400	COG0720	synthase
C0J07_RS09410	COG1289	transmembrane transporter activity
C0J07_RS09420	COG1566	PFAM secretion protein HlyD family protein
C0J07_RS09430	COG0400	carboxylic ester hydrolase activity
C0J07_RS09445	COG0587	DNA-directed DNA polymerase activity
C0J07_RS09450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS09465	COG1610	YqeY-like protein
C0J07_RS09545	COG3193	protein, possibly involved in utilization of glycolate and propanediol
C0J07_RS09570	COG1522	sequence-specific DNA binding
C0J07_RS09585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0J07_RS09615	COG0776	regulation of translation
C0J07_RS09620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0J07_RS09620	COG0072	phenylalanine-tRNA ligase activity
C0J07_RS09625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0J07_RS09630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0J07_RS09635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0J07_RS09645	COG2960	long-chain fatty acid transporting porin activity
C0J07_RS09670	COG0004	ammonium transporteR
C0J07_RS09700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0J07_RS09715	COG1090	epimerase
C0J07_RS09720	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C0J07_RS09720	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C0J07_RS09720	COG0506	proline dehydrogenase activity
C0J07_RS09730	COG3008	intermembrane lipid transfer
C0J07_RS09735	COG2995	paraquat-inducible protein a
C0J07_RS09740	COG0542	response to heat
C0J07_RS09745	COG4953	penicillin-binding protein 1C
C0J07_RS09755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C0J07_RS09760	COG1278	Cold shock
C0J07_RS09770	COG0183	Belongs to the thiolase family
C0J07_RS09775	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0J07_RS09780	COG1570	exodeoxyribonuclease VII activity
C0J07_RS09785	COG0811	peptide transport
C0J07_RS09795	COG1663	tetraacyldisaccharide 4'-kinase activity
C0J07_RS09800	COG2835	tetraacyldisaccharide 4'-kinase activity
C0J07_RS09805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C0J07_RS09810	COG0563	adenylate kinase activity
C0J07_RS09820	COG0728	peptidoglycan biosynthetic process
C0J07_RS09830	COG0268	Binds directly to 16S ribosomal RNA
C0J07_RS09835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0J07_RS09845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0J07_RS09850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0J07_RS09865	COG3158	transport of potassium into the cell
C0J07_RS09870	COG0642	Histidine kinase
C0J07_RS09900	COG0776	regulation of translation
C0J07_RS09905	COG0626	cystathionine gamma-synthase activity
C0J07_RS09910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0J07_RS09915	COG0557	exoribonuclease II activity
C0J07_RS09945	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C0J07_RS09950	COG2391	methyltransferase activity
C0J07_RS09960	COG0583	DNA-binding transcription factor activity
C0J07_RS09965	COG0069	glutamate synthase activity
C0J07_RS09975	COG0582	viral genome integration into host DNA
C0J07_RS10220	COG3706	GGDEF domain
C0J07_RS10225	COG3706	GGDEF domain
C0J07_RS10235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0J07_RS10260	COG3909	cytochrome
C0J07_RS10270	COG0625	glutathione transferase activity
C0J07_RS10275	COG0730	response to heat
C0J07_RS10280	COG0482	sulfurtransferase activity
C0J07_RS10300	COG0247	lactate metabolic process
C0J07_RS10305	COG0277	FAD linked oxidase domain protein
C0J07_RS10310	COG0277	FAD linked oxidase domain protein
C0J07_RS10315	COG0277	FAD linked oxidase domain protein
C0J07_RS10320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0J07_RS10325	COG0312	modulator of DNA gyrase
C0J07_RS10340	COG0308	aminopeptidase N
C0J07_RS10345	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C0J07_RS10350	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS10350	COG3064	Membrane
C0J07_RS10350	COG3210	domain, Protein
C0J07_RS10360	COG3210	domain, Protein
C0J07_RS10360	COG3064	Membrane
C0J07_RS10360	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS10380	COG0436	Aminotransferase
C0J07_RS10385	COG3737	Protein of unknown function (DUF498/DUF598)
C0J07_RS10390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0J07_RS10395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0J07_RS10400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0J07_RS10410	COG0305	Participates in initiation and elongation during chromosome replication
C0J07_RS10420	COG0359	binds to the 23S rRNA
C0J07_RS10425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C0J07_RS10430	COG2965	DNA replication, synthesis of RNA primer
C0J07_RS10435	COG0360	Binds together with S18 to 16S ribosomal RNA
C0J07_RS10440	COG1469	GTP cyclohydrolase I activity
C0J07_RS10445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C0J07_RS10450	COG0142	geranyltranstransferase activity
C0J07_RS10455	COG1722	exodeoxyribonuclease VII activity
C0J07_RS10480	COG0501	Belongs to the peptidase M48B family
C0J07_RS10495	COG0697	spore germination
C0J07_RS10505	COG1846	Transcriptional regulator
C0J07_RS10510	COG1538	Outer membrane efflux protein
C0J07_RS10515	COG1566	PFAM secretion protein HlyD family protein
C0J07_RS10520	COG2814	Major facilitator Superfamily
C0J07_RS10525	COG0473	3-isopropylmalate dehydrogenase activity
C0J07_RS10535	COG0747	negative chemotaxis
C0J07_RS10540	COG0601	transmembrane transport
C0J07_RS10545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS10555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0J07_RS10580	COG1012	belongs to the aldehyde dehydrogenase family
C0J07_RS10590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0J07_RS10600	COG0217	transcriptional regulatory protein
C0J07_RS10605	COG0151	Belongs to the GarS family
C0J07_RS10615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0J07_RS10620	COG0799	negative regulation of ribosome biogenesis
C0J07_RS10625	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C0J07_RS10630	COG0424	maF-like protein
C0J07_RS10650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0J07_RS10650	COG2169	Transcriptional regulator
C0J07_RS10655	COG1301	dicarboxylic acid transport
C0J07_RS10660	COG4191	Histidine kinase
C0J07_RS10665	COG2204	response regulator
C0J07_RS10680	COG1418	mRNA catabolic process
C0J07_RS10685	COG0500	methyltransferase
C0J07_RS10690	COG0477	Major facilitator Superfamily
C0J07_RS10700	COG0583	DNA-binding transcription factor activity
C0J07_RS10735	COG1530	ribonuclease E activity
C0J07_RS10740	COG1132	(ABC) transporter
C0J07_RS10760	COG0297	glycogen (starch) synthase activity
C0J07_RS10765	COG0726	polysaccharide deacetylase
C0J07_RS10770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0J07_RS10775	COG0463	Glycosyl transferase, family 2
C0J07_RS10780	COG0726	polysaccharide deacetylase
C0J07_RS10785	COG0438	transferase activity, transferring glycosyl groups
C0J07_RS10800	COG1643	Atp-dependent helicase
C0J07_RS10805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0J07_RS10805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0J07_RS10810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C0J07_RS10820	COG0704	Plays a role in the regulation of phosphate uptake
C0J07_RS10825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C0J07_RS10830	COG1322	Protein conserved in bacteria
C0J07_RS10840	COG2094	Belongs to the DNA glycosylase MPG family
C0J07_RS10850	COG1177	transmembrane transport
C0J07_RS10855	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0J07_RS10860	COG3842	ATPase activity
C0J07_RS10870	COG3642	lipopolysaccharide core region biosynthetic process
C0J07_RS10875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C0J07_RS10880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C0J07_RS10915	COG0135	phosphoribosylanthranilate isomerase activity
C0J07_RS10920	COG0101	tRNA pseudouridine synthase activity
C0J07_RS10930	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0J07_RS10935	COG0473	3-isopropylmalate dehydrogenase activity
C0J07_RS10940	COG0066	3-isopropylmalate dehydratase activity
C0J07_RS10950	COG0501	Belongs to the peptidase M48B family
C0J07_RS10955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C0J07_RS10965	COG2205	protein histidine kinase activity
C0J07_RS10975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0J07_RS10980	COG1295	ribonuclease BN
C0J07_RS10990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0J07_RS10995	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0J07_RS11060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C0J07_RS11075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C0J07_RS11095	COG0181	hydroxymethylbilane synthase activity
C0J07_RS11100	COG0861	Integral membrane protein TerC family
C0J07_RS11105	COG0861	Integral membrane protein TerC family
C0J07_RS11110	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0J07_RS11115	COG0045	succinate-CoA ligase (ADP-forming) activity
C0J07_RS11125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0J07_RS11135	COG2137	regulation of response to DNA damage stimulus
C0J07_RS11140	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C0J07_RS11155	COG0477	Major facilitator Superfamily
C0J07_RS11160	COG2974	May be involved in recombination
C0J07_RS11165	COG0540	Belongs to the ATCase OTCase family
C0J07_RS11195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS11210	COG3437	response regulator, receiver
C0J07_RS11210	COG2770	Histidine kinase
C0J07_RS11225	COG1278	Cold shock
C0J07_RS11455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0J07_RS11460	COG3723	Recombinational DNA repair protein, rece pathway
C0J07_RS11505	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C0J07_RS11525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0J07_RS11535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0J07_RS11540	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
C0J07_RS11545	COG0330	HflC and HflK could
C0J07_RS11550	COG0330	HflC and HflK could
C0J07_RS11555	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0J07_RS11560	COG1923	regulation of RNA biosynthetic process
C0J07_RS11565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0J07_RS11570	COG1160	GTP binding
C0J07_RS11575	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0J07_RS11580	COG2976	Protein conserved in bacteria
C0J07_RS11585	COG0124	histidyl-tRNA synthetase
C0J07_RS11600	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C0J07_RS11605	COG0105	UTP biosynthetic process
C0J07_RS11610	COG0525	valine-tRNA ligase activity
C0J07_RS11615	COG0336	Belongs to the RNA methyltransferase TrmD family
C0J07_RS11620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C0J07_RS11625	COG0228	four-way junction DNA binding
C0J07_RS11635	COG0425	Belongs to the sulfur carrier protein TusA family
C0J07_RS11640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0J07_RS11685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS11690	COG0543	2 iron, 2 sulfur cluster binding
C0J07_RS11690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0J07_RS11695	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
C0J07_RS11700	COG2076	Multidrug Resistance protein
C0J07_RS11705	COG3217	Mosc domain protein beta barrel domain protein
C0J07_RS11705	COG0633	Ferredoxin
C0J07_RS11710	COG5285	phytanoyl-CoA dioxygenase
C0J07_RS11715	COG0662	Cupin 2, conserved barrel domain protein
C0J07_RS11725	COG0456	acetyltransferase
C0J07_RS11755	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C0J07_RS11765	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C0J07_RS11770	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C0J07_RS11775	COG1760	l-serine dehydratase
C0J07_RS11780	COG1283	sodium-dependent phosphate transmembrane transporter activity
C0J07_RS11785	COG0412	Dienelactone hydrolase
C0J07_RS11795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0J07_RS11795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0J07_RS11800	COG1611	Belongs to the LOG family
C0J07_RS11810	COG1217	gtp-binding protein TYPA
C0J07_RS11815	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C0J07_RS11820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C0J07_RS11825	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C0J07_RS11830	COG2251	uridine kinase activity
C0J07_RS11830	COG0195	Participates in both transcription termination and antitermination
C0J07_RS11835	COG0779	Required for maturation of 30S ribosomal subunits
C0J07_RS11845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C0J07_RS11855	COG0523	cobalamin synthesis protein
C0J07_RS11870	COG0625	glutathione transferase activity
C0J07_RS11875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C0J07_RS11885	COG2003	Belongs to the UPF0758 family
C0J07_RS11890	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
C0J07_RS11895	COG3483	tryptophan 2,3-dioxygenase activity
C0J07_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS11940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0J07_RS11945	COG1562	ergosterol biosynthetic process
C0J07_RS11950	COG1562	ergosterol biosynthetic process
C0J07_RS11955	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C0J07_RS11960	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C0J07_RS11970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
C0J07_RS11975	COG0583	DNA-binding transcription factor activity
C0J07_RS11980	COG0542	response to heat
C0J07_RS11985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0J07_RS12000	COG0494	nUDIX hydrolase
C0J07_RS12010	COG0583	DNA-binding transcription factor activity
C0J07_RS12015	COG3530	Putative quorum-sensing-regulated virulence factor
C0J07_RS12055	COG2814	Major facilitator Superfamily
C0J07_RS12065	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
C0J07_RS12075	COG0628	permease
C0J07_RS12080	COG0842	Transport permease protein
C0J07_RS12085	COG1131	(ABC) transporter
C0J07_RS12090	COG1764	response to oxidative stress
C0J07_RS12095	COG1846	Transcriptional regulator
C0J07_RS12100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C0J07_RS12105	COG0156	8-amino-7-oxononanoate synthase activity
C0J07_RS12115	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C0J07_RS12115	COG4106	trans-aconitate 2-methyltransferase activity
C0J07_RS12135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C0J07_RS12135	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C0J07_RS12145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0J07_RS12150	COG0322	excinuclease ABC activity
C0J07_RS12155	COG1472	Belongs to the glycosyl hydrolase 3 family
C0J07_RS12160	COG0736	holo-[acyl-carrier-protein] synthase activity
C0J07_RS12165	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C0J07_RS12175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0J07_RS12180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0J07_RS12185	COG0745	RESPONSE REGULATOR receiver
C0J07_RS12200	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0J07_RS12205	COG4149	molybdate abc transporter
C0J07_RS12210	COG0725	ABC transporter, periplasmic molybdate-binding protein
C0J07_RS12215	COG1122	ATPase activity
C0J07_RS12220	COG4120	Belongs to the binding-protein-dependent transport system permease family
C0J07_RS12225	COG2984	ABC transporter substrate binding protein
C0J07_RS12235	COG2032	superoxide dismutase activity
C0J07_RS12250	COG0183	Belongs to the thiolase family
C0J07_RS12260	COG4175	Glycine betaine
C0J07_RS12260	COG3448	diguanylate cyclase activity
C0J07_RS12265	COG4176	ABC-type proline glycine betaine transport system permease component
C0J07_RS12275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C0J07_RS12280	COG2814	Major facilitator Superfamily
C0J07_RS12285	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0J07_RS12290	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0J07_RS12315	COG2814	Major facilitator Superfamily
C0J07_RS12320	COG0495	leucyl-tRNA aminoacylation
C0J07_RS12335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C0J07_RS12350	COG0154	amidase activity
C0J07_RS12395	COG0427	acetyl-CoA hydrolase
C0J07_RS12400	COG0583	DNA-binding transcription factor activity
C0J07_RS12405	COG3264	Mechanosensitive ion channel
C0J07_RS12405	COG1511	domain protein
C0J07_RS12415	COG0697	spore germination
C0J07_RS12440	COG0243	molybdopterin cofactor binding
C0J07_RS12460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C0J07_RS12465	COG3384	dioxygenase
C0J07_RS12480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C0J07_RS12485	COG4221	oxidoreductase activity
C0J07_RS12495	COG2814	Major facilitator Superfamily
C0J07_RS12500	COG0583	DNA-binding transcription factor activity
C0J07_RS12565	COG3300	MHYT domain
C0J07_RS12565	COG5001	Diguanylate cyclase
C0J07_RS12585	COG4172	Belongs to the ABC transporter superfamily
C0J07_RS12590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS12595	COG0601	transmembrane transport
C0J07_RS12600	COG0747	negative chemotaxis
C0J07_RS12610	COG0598	Magnesium transport protein CorA
C0J07_RS12620	COG1801	Protein of unknown function DUF72
C0J07_RS12630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C0J07_RS12635	COG1012	belongs to the aldehyde dehydrogenase family
C0J07_RS12645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0J07_RS12650	COG1045	serine acetyltransferase
C0J07_RS12660	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0J07_RS12660	COG1024	Enoyl-CoA hydratase
C0J07_RS12665	COG0183	Belongs to the thiolase family
C0J07_RS12680	COG1902	pentaerythritol trinitrate reductase activity
C0J07_RS12710	COG4695	Portal protein
C0J07_RS12880	COG0582	viral genome integration into host DNA
C0J07_RS12890	COG0527	aspartate kinase activity
C0J07_RS12900	COG0825	malonyl-CoA metabolic process
C0J07_RS12910	COG0215	cysteine-tRNA ligase activity
C0J07_RS12920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0J07_RS12925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0J07_RS12930	COG1968	undecaprenyl-diphosphatase activity
C0J07_RS12935	COG1253	flavin adenine dinucleotide binding
C0J07_RS12940	COG0483	inositol monophosphate 1-phosphatase activity
C0J07_RS12970	COG0668	transmembrane transport
C0J07_RS13020	COG1802	Transcriptional regulator
C0J07_RS13040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C0J07_RS13045	COG2850	peptidyl-arginine hydroxylation
C0J07_RS13060	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C0J07_RS13065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0J07_RS13070	COG1994	Peptidase M50
C0J07_RS13075	COG0009	L-threonylcarbamoyladenylate synthase
C0J07_RS13080	COG2321	neutral zinc metallopeptidase
C0J07_RS13105	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0J07_RS13120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0J07_RS13125	COG1404	Belongs to the peptidase S8 family
C0J07_RS13185	COG0531	amino acid
C0J07_RS13195	COG0076	glutamate decarboxylase activity
C0J07_RS13220	COG0457	Tetratricopeptide repeat
C0J07_RS13225	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
C0J07_RS13230	COG1215	transferase activity, transferring glycosyl groups
C0J07_RS13235	COG1215	transferase activity, transferring glycosyl groups
C0J07_RS13240	COG1215	transferase activity, transferring glycosyl groups
C0J07_RS13245	COG1192	Involved in chromosome partitioning
C0J07_RS13275	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
C0J07_RS13280	COG1596	polysaccharide export
C0J07_RS13305	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS13345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
C0J07_RS13355	COG4604	ABC transporter, ATP-binding protein
C0J07_RS13360	COG4605	iron ion homeostasis
C0J07_RS13365	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0J07_RS13370	COG4607	ABC-type enterochelin transport system periplasmic component
C0J07_RS13375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0J07_RS13380	COG0149	triose-phosphate isomerase activity
C0J07_RS13385	COG3321	synthase
C0J07_RS13385	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS13385	COG0604	alcohol dehydrogenase
C0J07_RS13410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0J07_RS13420	COG0154	amidase activity
C0J07_RS13425	COG1185	polyribonucleotide nucleotidyltransferase activity
C0J07_RS13430	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0J07_RS13440	COG1183	phosphatidylcholine synthase activity
C0J07_RS13445	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C0J07_RS13450	COG0440	acetolactate synthase activity
C0J07_RS13455	COG0028	Belongs to the TPP enzyme family
C0J07_RS13460	COG1289	transmembrane transporter activity
C0J07_RS13465	COG3022	response to hydroperoxide
C0J07_RS13470	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS13480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0J07_RS13485	COG0640	Transcriptional regulator
C0J07_RS13500	COG5001	Diguanylate cyclase
C0J07_RS13500	COG5002	protein histidine kinase activity
C0J07_RS13520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0J07_RS13525	COG0531	amino acid
C0J07_RS13530	COG1982	Orn Lys Arg decarboxylase major
C0J07_RS13545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0J07_RS13555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C0J07_RS13560	COG1674	ftsk spoiiie
C0J07_RS13565	COG0492	ferredoxin-NADP+ reductase activity
C0J07_RS13570	COG1193	negative regulation of DNA recombination
C0J07_RS13580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0J07_RS13595	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C0J07_RS13600	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C0J07_RS13605	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
C0J07_RS13610	COG2205	protein histidine kinase activity
C0J07_RS13615	COG0745	RESPONSE REGULATOR receiver
C0J07_RS13630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0J07_RS13645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0J07_RS13660	COG0612	Peptidase, M16
C0J07_RS13665	COG0484	heat shock protein binding
C0J07_RS13670	COG0443	Heat shock 70 kDa protein
C0J07_RS13680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C0J07_RS13685	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C0J07_RS13690	COG1420	regulation of RNA biosynthetic process
C0J07_RS13695	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0J07_RS13700	COG0497	DNA recombination
C0J07_RS13705	COG0735	belongs to the Fur family
C0J07_RS13710	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0J07_RS13735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0J07_RS13740	COG1683	Conserved Protein
C0J07_RS13755	COG2828	Protein conserved in bacteria
C0J07_RS13760	COG1280	lysine exporter protein (LysE YggA)
C0J07_RS13770	COG0582	viral genome integration into host DNA
C0J07_RS13780	COG1396	sequence-specific DNA binding
C0J07_RS13785	COG0583	DNA-binding transcription factor activity
C0J07_RS13790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C0J07_RS13795	COG0159	tryptophan synthase activity
C0J07_RS13800	COG0133	tryptophan synthase activity
C0J07_RS13805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0J07_RS13810	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C0J07_RS13815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C0J07_RS13830	COG3135	benzoate transporter
C0J07_RS13840	COG1794	racemase activity, acting on amino acids and derivatives
C0J07_RS13845	COG0583	DNA-binding transcription factor activity
C0J07_RS13930	COG2003	Belongs to the UPF0758 family
C0J07_RS13990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0J07_RS13995	COG1196	nuclear chromosome segregation
C0J07_RS14005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C0J07_RS14130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C0J07_RS14135	COG0629	single-stranded DNA binding
C0J07_RS14215	COG1335	isochorismatase
C0J07_RS14220	COG2309	aminopeptidase activity
C0J07_RS14225	COG0596	Alpha beta hydrolase
C0J07_RS14230	COG3473	Maleate cis-trans isomerase
C0J07_RS14260	COG0583	DNA-binding transcription factor activity
C0J07_RS14270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C0J07_RS14275	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C0J07_RS14280	COG0167	dihydroorotate dehydrogenase activity
C0J07_RS14295	COG1414	Transcriptional regulator
C0J07_RS14300	COG1546	Belongs to the CinA family
C0J07_RS14300	COG1058	Belongs to the CinA family
C0J07_RS14315	COG0513	Belongs to the DEAD box helicase family
C0J07_RS14340	COG0429	hydrolase of the alpha beta-hydrolase fold
C0J07_RS14345	COG4783	chaperone-mediated protein folding
C0J07_RS14355	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0J07_RS14375	COG0006	proline dipeptidase activity
C0J07_RS14380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0J07_RS14400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C0J07_RS14405	COG0632	four-way junction helicase activity
C0J07_RS14415	COG2255	four-way junction helicase activity
C0J07_RS14420	COG0514	ATP-dependent DNA helicase (RecQ)
C0J07_RS14450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0J07_RS14455	COG0850	regulation of cytokinetic process
C0J07_RS14460	COG2894	cell division
C0J07_RS14465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C0J07_RS14480	COG0488	(ABC) transporter
C0J07_RS14485	COG2066	Belongs to the glutaminase family
C0J07_RS14490	COG0531	amino acid
C0J07_RS14500	COG0076	glutamate decarboxylase activity
C0J07_RS14515	COG4608	Belongs to the ABC transporter superfamily
C0J07_RS14520	COG0444	Belongs to the ABC transporter superfamily
C0J07_RS14525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS14530	COG0601	transmembrane transport
C0J07_RS14535	COG0747	negative chemotaxis
C0J07_RS14540	COG1215	transferase activity, transferring glycosyl groups
C0J07_RS14550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C0J07_RS14555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0J07_RS14565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0J07_RS14570	COG1538	Outer membrane efflux protein
C0J07_RS14575	COG0577	efflux transmembrane transporter activity
C0J07_RS14575	COG1136	(ABC) transporter
C0J07_RS14590	COG0405	Gamma-glutamyltransferase
C0J07_RS14610	COG0579	oxidoreductase
C0J07_RS14615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C0J07_RS14620	COG0259	pyridoxamine-phosphate oxidase activity
C0J07_RS14685	COG1368	sulfuric ester hydrolase activity
C0J07_RS14740	COG2982	Protein involved in outer membrane biogenesis
C0J07_RS14745	COG2818	Glycosylase
C0J07_RS14750	COG0727	PFAM Uncharacterised protein family (UPF0153)
C0J07_RS14765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C0J07_RS14775	COG1464	Belongs to the NlpA lipoprotein family
C0J07_RS14780	COG2011	ABC-type metal ion transport system permease component
C0J07_RS14785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0J07_RS14790	COG1501	Belongs to the glycosyl hydrolase 31 family
C0J07_RS14795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0J07_RS14795	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C0J07_RS14805	COG0318	PFAM AMP-dependent synthetase and ligase
C0J07_RS14810	COG1473	amidohydrolase
C0J07_RS14815	COG0583	DNA-binding transcription factor activity
C0J07_RS14820	COG2855	membrane
C0J07_RS14830	COG2239	Acts as a magnesium transporter
C0J07_RS14845	COG1522	sequence-specific DNA binding
C0J07_RS14860	COG0653	protein targeting
C0J07_RS14865	COG0739	heme binding
C0J07_RS14880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C0J07_RS14895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C0J07_RS14900	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0J07_RS14905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0J07_RS14910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0J07_RS14920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C0J07_RS14925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0J07_RS14930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C0J07_RS14940	COG3116	cell division
C0J07_RS14945	COG0275	rRNA processing
C0J07_RS14950	COG2001	Belongs to the MraZ family
C0J07_RS14960	COG0488	(ABC) transporter
C0J07_RS14965	COG0418	dihydroorotase activity
C0J07_RS14970	COG1473	amidohydrolase
C0J07_RS15025	COG4654	Cytochrome c, class I
C0J07_RS15030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C0J07_RS15065	COG2084	Dehydrogenase
C0J07_RS15070	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C0J07_RS15100	COG0442	prolyl-tRNA aminoacylation
C0J07_RS15105	COG0824	Thioesterase
C0J07_RS15110	COG0811	peptide transport
C0J07_RS15115	COG0848	biopolymer transport protein
C0J07_RS15125	COG0823	Involved in the tonB-independent uptake of proteins
C0J07_RS15145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C0J07_RS15160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0J07_RS15165	COG0697	spore germination
C0J07_RS15190	COG0463	Glycosyl transferase, family 2
C0J07_RS15210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0J07_RS15215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0J07_RS15220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0J07_RS15225	COG0328	RNA-DNA hybrid ribonuclease activity
C0J07_RS15230	COG2226	methyltransferase
C0J07_RS15235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0J07_RS15240	COG0741	lytic transglycosylase activity
C0J07_RS15240	COG1388	LysM domain
C0J07_RS15285	COG2816	NAD+ diphosphatase activity
C0J07_RS15325	COG2719	SpoVR family
C0J07_RS15330	COG2718	Belongs to the UPF0229 family
C0J07_RS15335	COG2766	serine protein kinase
C0J07_RS15345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0J07_RS15345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0J07_RS15360	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0J07_RS15365	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C0J07_RS15375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C0J07_RS15385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C0J07_RS15390	COG0316	Belongs to the HesB IscA family
C0J07_RS15400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C0J07_RS15405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0J07_RS15410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C0J07_RS15415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C0J07_RS15425	COG0312	modulator of DNA gyrase
C0J07_RS15430	COG3028	Belongs to the UPF0307 family
C0J07_RS15440	COG1042	CoA-binding domain protein
C0J07_RS15440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0J07_RS15440	COG1042	CoA-binding domain protein
C0J07_RS15440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0J07_RS15440	COG0045	succinate-CoA ligase (ADP-forming) activity
C0J07_RS15440	COG0045	succinate-CoA ligase (ADP-forming) activity
C0J07_RS15445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0J07_RS15490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C0J07_RS15495	COG1696	Membrane protein involved in D-alanine export
C0J07_RS15530	COG2264	protein methyltransferase activity
C0J07_RS15535	COG0439	Biotin carboxylase
C0J07_RS15540	COG0511	ligase activity, forming carbon-carbon bonds
C0J07_RS15545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C0J07_RS15550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0J07_RS15555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0J07_RS15560	COG3150	esterase
C0J07_RS15565	COG0557	exoribonuclease II activity
C0J07_RS15575	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C0J07_RS15580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0J07_RS15590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0J07_RS15610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C0J07_RS15615	COG1678	Uncharacterized ACR, COG1678
C0J07_RS15625	COG0351	phosphomethylpyrimidine kinase
C0J07_RS15630	COG0352	thiamine-phosphate diphosphorylase activity
C0J07_RS15635	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C0J07_RS15660	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS15665	COG1024	Enoyl-CoA hydratase
C0J07_RS15670	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS15700	COG0410	ABC transporter
C0J07_RS15750	COG3539	Fimbrial protein
C0J07_RS15775	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C0J07_RS15780	COG0237	dephospho-CoA kinase activity
C0J07_RS15785	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C0J07_RS15800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C0J07_RS15805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C0J07_RS15815	COG0477	Major facilitator Superfamily
C0J07_RS15835	COG1126	abc transporter atp-binding protein
C0J07_RS15840	COG0765	amino acid transport
C0J07_RS15845	COG4597	amino acid ABC transporter
C0J07_RS15850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0J07_RS15855	COG2884	Cell division ATP-binding protein ftsE
C0J07_RS15860	COG2177	Part of the ABC transporter FtsEX involved in
C0J07_RS15865	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C0J07_RS15885	COG2226	methyltransferase
C0J07_RS15895	COG4206	TonB-dependent receptor
C0J07_RS15900	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0J07_RS15905	COG2022	thiamine diphosphate biosynthetic process
C0J07_RS15910	COG0351	phosphomethylpyrimidine kinase
C0J07_RS15920	COG1538	Outer membrane efflux protein
C0J07_RS15925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C0J07_RS15935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0J07_RS15945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0J07_RS15950	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0J07_RS15980	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0J07_RS16005	COG2226	methyltransferase
C0J07_RS16010	COG0745	RESPONSE REGULATOR receiver
C0J07_RS16015	COG5002	protein histidine kinase activity
C0J07_RS16025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0J07_RS16030	COG0583	DNA-binding transcription factor activity
C0J07_RS16040	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C0J07_RS16045	COG1984	allophanate hydrolase subunit 2
C0J07_RS16055	COG1802	Transcriptional regulator
C0J07_RS16065	COG1238	metal cluster binding
C0J07_RS16070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C0J07_RS16075	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C0J07_RS16085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0J07_RS16090	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0J07_RS16095	COG4988	ABC transporter
C0J07_RS16100	COG4890	Cyd operon protein YbgT
C0J07_RS16105	COG1294	oxidase, subunit
C0J07_RS16120	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C0J07_RS16130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C0J07_RS16145	COG1137	ATPase activity
C0J07_RS16150	COG0443	Heat shock 70 kDa protein
C0J07_RS16155	COG2169	Transcriptional regulator
C0J07_RS16155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0J07_RS16160	COG3145	DNA-N1-methyladenine dioxygenase activity
C0J07_RS16165	COG0583	DNA-binding transcription factor activity
C0J07_RS16175	COG1473	amidohydrolase
C0J07_RS16180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0J07_RS16185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0J07_RS16200	COG1120	ATPase activity
C0J07_RS16205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0J07_RS16210	COG4558	Periplasmic binding protein
C0J07_RS16215	COG3720	iron ion transport
C0J07_RS16230	COG1595	DNA-templated transcription, initiation
C0J07_RS16250	COG1607	acyl-coa hydrolase
C0J07_RS16260	COG3383	formate dehydrogenase (NAD+) activity
C0J07_RS16260	COG0243	molybdopterin cofactor binding
C0J07_RS16265	COG0243	molybdopterin cofactor binding
C0J07_RS16265	COG3383	formate dehydrogenase (NAD+) activity
C0J07_RS16270	COG0437	4 iron, 4 sulfur cluster binding
C0J07_RS16275	COG2864	formate dehydrogenase
C0J07_RS16290	COG3276	selenocysteine insertion sequence binding
C0J07_RS16305	COG0583	DNA-binding transcription factor activity
C0J07_RS16315	COG0134	indole-3-glycerol-phosphate synthase activity
C0J07_RS16320	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0J07_RS16330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0J07_RS16340	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
C0J07_RS16345	COG1660	Displays ATPase and GTPase activities
C0J07_RS16350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0J07_RS16355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C0J07_RS16360	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C0J07_RS16365	COG0792	nuclease activity
C0J07_RS16370	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C0J07_RS16375	COG2823	Periplasmic or secreted lipoprotein
C0J07_RS16390	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0J07_RS16400	COG1309	transcriptional regulator
C0J07_RS16405	COG0471	metal ion transport
C0J07_RS16410	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
C0J07_RS16415	COG0772	Belongs to the SEDS family
C0J07_RS16420	COG0768	penicillin binding
C0J07_RS16430	COG1792	Involved in formation and maintenance of cell shape
C0J07_RS16435	COG1077	Cell shape determining protein MreB Mrl
C0J07_RS16440	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0J07_RS16445	COG0154	amidase activity
C0J07_RS16450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C0J07_RS16455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C0J07_RS16465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0J07_RS16470	COG2860	membrane
C0J07_RS16480	COG2223	nitrite transmembrane transporter activity
C0J07_RS16490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C0J07_RS16525	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0J07_RS16535	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS16545	COG2070	2-Nitropropane dioxygenase
C0J07_RS16550	COG1024	Enoyl-CoA hydratase
C0J07_RS16555	COG1024	Enoyl-CoA hydratase
C0J07_RS16560	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0J07_RS16570	COG0747	negative chemotaxis
C0J07_RS16575	COG0601	transmembrane transport
C0J07_RS16580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS16585	COG0444	Belongs to the ABC transporter superfamily
C0J07_RS16590	COG4608	Belongs to the ABC transporter superfamily
C0J07_RS16605	COG0210	DNA helicase
C0J07_RS16610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C0J07_RS16615	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C0J07_RS16625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C0J07_RS16630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C0J07_RS16635	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C0J07_RS16640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C0J07_RS16645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C0J07_RS16650	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C0J07_RS16660	COG0356	it plays a direct role in the translocation of protons across the membrane
C0J07_RS16670	COG1024	Enoyl-CoA hydratase
C0J07_RS16680	COG0492	ferredoxin-NADP+ reductase activity
C0J07_RS16690	COG0037	tRNA processing
C0J07_RS16700	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0J07_RS16705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0J07_RS16710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0J07_RS16715	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C0J07_RS16720	COG2967	ApaG domain
C0J07_RS16725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0J07_RS16730	COG0546	phosphoglycolate phosphatase activity
C0J07_RS16740	COG1671	Belongs to the UPF0178 family
C0J07_RS16755	COG0583	DNA-binding transcription factor activity
C0J07_RS16765	COG0129	dihydroxy-acid dehydratase activity
C0J07_RS16780	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
C0J07_RS16785	COG2326	polyphosphate kinase activity
C0J07_RS16790	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C0J07_RS16825	COG3181	Tripartite tricarboxylate transporter family receptor
C0J07_RS16830	COG0583	DNA-binding transcription factor activity
C0J07_RS16835	COG3976	FMN-binding domain protein
C0J07_RS16835	COG1053	succinate dehydrogenase
C0J07_RS16855	COG0431	NADPH-dependent FMN reductase
C0J07_RS16855	COG1053	succinate dehydrogenase
C0J07_RS16855	COG3976	FMN-binding domain protein
C0J07_RS16885	COG1053	succinate dehydrogenase
C0J07_RS16920	COG1522	sequence-specific DNA binding
C0J07_RS16935	COG2814	Major facilitator Superfamily
C0J07_RS16940	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C0J07_RS16955	COG1999	signal sequence binding
C0J07_RS16960	COG0109	protoheme IX farnesyltransferase activity
C0J07_RS16965	COG1612	heme a metabolic process
C0J07_RS16980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0J07_RS16985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0J07_RS17000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
C0J07_RS17015	COG0069	glutamate synthase activity
C0J07_RS17015	COG0070	glutamate synthase
C0J07_RS17015	COG0067	glutamate synthase
C0J07_RS17045	COG1984	allophanate hydrolase subunit 2
C0J07_RS17060	COG0511	ligase activity, forming carbon-carbon bonds
C0J07_RS17065	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C0J07_RS17075	COG3047	cAMP biosynthetic process
C0J07_RS17080	COG1127	ABC transporter
C0J07_RS17085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0J07_RS17090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0J07_RS17095	COG2853	Lipoprotein
C0J07_RS17105	COG1131	(ABC) transporter
C0J07_RS17110	COG0842	Transport permease protein
C0J07_RS17120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0J07_RS17125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C0J07_RS17130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C0J07_RS17135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0J07_RS17140	COG0131	Imidazoleglycerol-phosphate dehydratase
C0J07_RS17150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C0J07_RS17155	COG0107	imidazoleglycerol-phosphate synthase activity
C0J07_RS17160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0J07_RS17165	COG0140	phosphoribosyl-ATP diphosphatase activity
C0J07_RS17170	COG0537	adenosine 5'-monophosphoramidase activity
C0J07_RS17175	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0J07_RS17180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0J07_RS17190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0J07_RS17195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C0J07_RS17200	COG1970	mechanosensitive ion channel activity
C0J07_RS17205	COG0723	plastoquinol--plastocyanin reductase activity
C0J07_RS17210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0J07_RS17215	COG2857	Cytochrome c1
C0J07_RS17220	COG0625	glutathione transferase activity
C0J07_RS17225	COG2969	positive regulation of protein catabolic process
C0J07_RS17250	COG1160	GTP binding
C0J07_RS17260	COG0601	transmembrane transport
C0J07_RS17265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0J07_RS17275	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C0J07_RS17285	COG0513	Belongs to the DEAD box helicase family
C0J07_RS17290	COG1280	lysine exporter protein (LysE YggA)
C0J07_RS17295	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C0J07_RS17315	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C0J07_RS17325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0J07_RS17330	COG0154	amidase activity
C0J07_RS17335	COG1609	Transcriptional regulator
C0J07_RS17355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0J07_RS17360	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C0J07_RS17375	COG0018	arginyl-trna synthetase
C0J07_RS17385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0J07_RS17390	COG2200	EAL domain
C0J07_RS17400	COG1280	lysine exporter protein (LysE YggA)
C0J07_RS17415	COG1960	acyl-CoA dehydrogenase activity
C0J07_RS17420	COG0183	Belongs to the thiolase family
C0J07_RS17425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0J07_RS17440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0J07_RS17450	COG1629	transport
C0J07_RS17455	COG2922	Belongs to the Smg family
C0J07_RS17460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0J07_RS17475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0J07_RS17480	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C0J07_RS17485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0J07_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
C0J07_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
C0J07_RS17505	COG0028	Belongs to the TPP enzyme family
C0J07_RS17510	COG1522	sequence-specific DNA binding
C0J07_RS17515	COG3781	membrane
C0J07_RS17540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0J07_RS17545	COG1744	ABC transporter substrate-binding protein PnrA-like
C0J07_RS17550	COG3845	ABC transporter
C0J07_RS17555	COG4603	Belongs to the binding-protein-dependent transport system permease family
C0J07_RS17560	COG1079	Belongs to the binding-protein-dependent transport system permease family
C0J07_RS17565	COG0402	S-adenosylhomocysteine deaminase activity
C0J07_RS17580	COG1254	Belongs to the acylphosphatase family
C0J07_RS17585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C0J07_RS17585	COG2010	Cytochrome c
C0J07_RS17595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C0J07_RS17610	COG1690	Belongs to the RtcB family
C0J07_RS17615	COG4650	regulator
C0J07_RS17630	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0J07_RS17635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C0J07_RS17640	COG0594	ribonuclease P activity
C0J07_RS17645	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0J07_RS17650	COG0706	membrane insertase activity
C0J07_RS17655	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C0J07_RS17660	COG1473	amidohydrolase
C0J07_RS17665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C0J07_RS17670	COG1505	serine-type exopeptidase activity
C0J07_RS17680	COG0280	phosphate acetyltransferase
C0J07_RS17680	COG0281	malic enzyme
C0J07_RS17695	COG0436	Aminotransferase
C0J07_RS17700	COG1278	Cold shock