locus-tag	class	description
BTL45_RS00005	COG0445	tRNA wobble uridine modification
BTL45_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BTL45_RS00015	COG1192	Involved in chromosome partitioning
BTL45_RS00025	COG1475	DNA binding
BTL45_RS00030	COG0252	asparaginase activity
BTL45_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL45_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTL45_RS00075	COG0081	regulation of translation
BTL45_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTL45_RS00085	COG0222	ribosome binding
BTL45_RS00090	COG0085	RNA polymerase activity
BTL45_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTL45_RS00130	COG1230	cation diffusion facilitator family transporter
BTL45_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTL45_RS00145	COG0049	tRNA binding
BTL45_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL45_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTL45_RS00160	COG0051	transcription antitermination factor activity, RNA binding
BTL45_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTL45_RS00175	COG0089	rRNA binding
BTL45_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTL45_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BTL45_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTL45_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTL45_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
BTL45_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTL45_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTL45_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTL45_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTL45_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTL45_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTL45_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BTL45_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTL45_RS00270	COG1841	ribosomal large subunit assembly
BTL45_RS00275	COG0200	Binds to the 23S rRNA
BTL45_RS00280	COG0201	protein transport
BTL45_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL45_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTL45_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTL45_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTL45_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTL45_RS00310	COG0202	RNA polymerase activity
BTL45_RS00315	COG0203	ribosomal protein L17
BTL45_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
BTL45_RS00325	COG1324	tolerance protein
BTL45_RS00330	COG4232	protein-disulfide reductase activity
BTL45_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BTL45_RS00355	COG1333	cytochrome c biogenesis protein
BTL45_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTL45_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BTL45_RS00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTL45_RS00395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTL45_RS00410	COG2814	Major facilitator Superfamily
BTL45_RS00415	COG0629	single-stranded DNA binding
BTL45_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
BTL45_RS00460	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS00505	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTL45_RS00510	COG2186	Transcriptional regulator
BTL45_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS00535	COG1956	GAF domain-containing protein
BTL45_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS00570	COG0531	amino acid
BTL45_RS00600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTL45_RS00605	COG3568	Endonuclease Exonuclease Phosphatase
BTL45_RS00610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL45_RS00620	COG0477	Major facilitator Superfamily
BTL45_RS00630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL45_RS00640	COG0367	asparagine synthase
BTL45_RS00660	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTL45_RS00665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTL45_RS00705	COG0367	asparagine synthase
BTL45_RS00710	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BTL45_RS00735	COG0367	asparagine synthase
BTL45_RS00745	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS00765	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS00770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTL45_RS00775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTL45_RS00805	COG0859	PFAM glycosyl transferase family 9
BTL45_RS00820	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BTL45_RS00830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL45_RS00835	COG1127	ABC transporter
BTL45_RS00855	COG1686	Belongs to the peptidase S11 family
BTL45_RS00865	COG2921	Belongs to the UPF0250 family
BTL45_RS00870	COG0321	lipoyl(octanoyl) transferase activity
BTL45_RS00875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BTL45_RS00895	COG2096	Adenosyltransferase
BTL45_RS00905	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BTL45_RS00920	COG0523	cobalamin synthesis protein
BTL45_RS00925	COG0735	belongs to the Fur family
BTL45_RS00935	COG1121	(ABC) transporter
BTL45_RS00945	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTL45_RS00955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BTL45_RS00965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BTL45_RS00975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTL45_RS00980	COG1560	Kdo2-lipid A biosynthetic process
BTL45_RS00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTL45_RS01005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BTL45_RS01010	COG1950	PFAM Membrane protein of
BTL45_RS01020	COG0583	DNA-binding transcription factor activity
BTL45_RS01030	COG0477	Major facilitator Superfamily
BTL45_RS01045	COG0617	tRNA 3'-terminal CCA addition
BTL45_RS01055	COG0513	Belongs to the DEAD box helicase family
BTL45_RS01060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BTL45_RS01065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL45_RS01070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL45_RS01090	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS01115	COG0640	Transcriptional regulator
BTL45_RS01175	COG0583	DNA-binding transcription factor activity
BTL45_RS01190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTL45_RS01195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS01200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS01215	COG0758	DNA mediated transformation
BTL45_RS01220	COG1522	sequence-specific DNA binding
BTL45_RS01230	COG0242	peptide deformylase activity
BTL45_RS01235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTL45_RS01245	COG0546	phosphoglycolate phosphatase activity
BTL45_RS01265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTL45_RS01270	COG1942	4-Oxalocrotonate Tautomerase
BTL45_RS01275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL45_RS01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL45_RS01315	COG5000	phosphorelay sensor kinase activity
BTL45_RS01320	COG2204	response regulator
BTL45_RS01345	COG2068	MobA-Related Protein
BTL45_RS01355	COG3473	Maleate cis-trans isomerase
BTL45_RS01360	COG0596	Alpha beta hydrolase
BTL45_RS01365	COG2309	aminopeptidase activity
BTL45_RS01370	COG1335	isochorismatase
BTL45_RS01395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS01425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS01445	COG2226	methyltransferase
BTL45_RS01460	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS01465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTL45_RS01470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BTL45_RS01475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL45_RS01480	COG1054	Belongs to the UPF0176 family
BTL45_RS01485	COG0588	phosphoglycerate mutase activity
BTL45_RS01490	COG4942	peptidase
BTL45_RS01495	COG0793	Belongs to the peptidase S41A family
BTL45_RS01500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTL45_RS01515	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS01525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL45_RS01555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTL45_RS01560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTL45_RS01565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTL45_RS01570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTL45_RS01580	COG0142	geranyltranstransferase activity
BTL45_RS01590	COG0583	DNA-binding transcription factor activity
BTL45_RS01600	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BTL45_RS01605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS01620	COG2994	toxin metabolic process
BTL45_RS01630	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BTL45_RS01635	COG2274	protein secretion by the type I secretion system
BTL45_RS01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS01645	COG1538	Outer membrane efflux protein
BTL45_RS01660	COG0765	amino acid transport
BTL45_RS01665	COG0765	amino acid transport
BTL45_RS01670	COG1126	abc transporter atp-binding protein
BTL45_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS01700	COG1802	Transcriptional regulator
BTL45_RS01710	COG1802	Transcriptional regulator
BTL45_RS01720	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS01730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS01750	COG0028	Belongs to the TPP enzyme family
BTL45_RS01760	COG0583	DNA-binding transcription factor activity
BTL45_RS01765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS01770	COG2301	Belongs to the HpcH HpaI aldolase family
BTL45_RS01775	COG2188	Transcriptional regulator
BTL45_RS01820	COG0583	DNA-binding transcription factor activity
BTL45_RS01825	COG1024	Enoyl-CoA hydratase
BTL45_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS01875	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS01910	COG0745	RESPONSE REGULATOR receiver
BTL45_RS01945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTL45_RS01950	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL45_RS01955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTL45_RS01965	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02000	COG1464	Belongs to the NlpA lipoprotein family
BTL45_RS02040	COG4211	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS02045	COG0583	DNA-binding transcription factor activity
BTL45_RS02050	COG0683	leucine binding
BTL45_RS02055	COG0154	amidase activity
BTL45_RS02060	COG0288	reversible hydration of carbon dioxide
BTL45_RS02080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL45_RS02095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTL45_RS02105	COG1414	Transcriptional regulator
BTL45_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS02115	COG2031	fatty acid transporter
BTL45_RS02120	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS02130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BTL45_RS02135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BTL45_RS02150	COG2808	Putative FMN-binding domain
BTL45_RS02160	COG0747	negative chemotaxis
BTL45_RS02165	COG0657	acetylesterase activity
BTL45_RS02175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL45_RS02180	COG2207	Transcriptional regulator
BTL45_RS02185	COG0129	dihydroxy-acid dehydratase activity
BTL45_RS02190	COG2814	Major facilitator Superfamily
BTL45_RS02195	COG0583	DNA-binding transcription factor activity
BTL45_RS02200	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BTL45_RS02205	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BTL45_RS02215	COG1538	Outer membrane efflux protein
BTL45_RS02230	COG0583	DNA-binding transcription factor activity
BTL45_RS02235	COG0628	permease
BTL45_RS02245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTL45_RS02250	COG0251	oxidation-reduction process
BTL45_RS02260	COG0330	HflC and HflK could
BTL45_RS02265	COG3422	double-strand break repair
BTL45_RS02280	COG0583	DNA-binding transcription factor activity
BTL45_RS02315	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02320	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS02325	COG1414	Transcriptional regulator
BTL45_RS02330	COG1024	Enoyl-CoA hydratase
BTL45_RS02335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS02345	COG0604	alcohol dehydrogenase
BTL45_RS02360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02375	COG0251	oxidation-reduction process
BTL45_RS02380	COG1017	nitric oxide dioxygenase activity
BTL45_RS02380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL45_RS02385	COG2031	fatty acid transporter
BTL45_RS02410	COG1278	Cold shock
BTL45_RS02415	COG0583	DNA-binding transcription factor activity
BTL45_RS02425	COG3119	arylsulfatase activity
BTL45_RS02435	COG1819	glycosyl
BTL45_RS02480	COG0326	Molecular chaperone. Has ATPase activity
BTL45_RS02490	COG0625	glutathione transferase activity
BTL45_RS02505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTL45_RS02510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTL45_RS02515	COG1652	LysM domain
BTL45_RS02530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BTL45_RS02540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL45_RS02590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS02630	COG0583	DNA-binding transcription factor activity
BTL45_RS02635	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02645	COG1024	Enoyl-CoA hydratase
BTL45_RS02650	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02675	COG0028	Belongs to the TPP enzyme family
BTL45_RS02680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02685	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS02685	COG1024	Enoyl-CoA hydratase
BTL45_RS02690	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02695	COG1414	Transcriptional regulator
BTL45_RS02715	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS02720	COG1609	Transcriptional regulator
BTL45_RS02730	COG3976	FMN-binding domain protein
BTL45_RS02730	COG1053	succinate dehydrogenase
BTL45_RS02765	COG0683	leucine binding
BTL45_RS02770	COG1309	transcriptional regulator
BTL45_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS02795	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS02800	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS02805	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS02815	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTL45_RS02820	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS02845	COG2030	dehydratase
BTL45_RS02855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02865	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS02890	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS02910	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS02910	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTL45_RS02925	COG0427	acetyl-CoA hydrolase
BTL45_RS02930	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS02945	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTL45_RS02950	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS02965	COG0183	Belongs to the thiolase family
BTL45_RS02970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL45_RS02980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS02985	COG0583	DNA-binding transcription factor activity
BTL45_RS02990	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS03005	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BTL45_RS03035	COG1309	transcriptional regulator
BTL45_RS03045	COG1024	Enoyl-CoA hydratase
BTL45_RS03065	COG1024	Enoyl-CoA hydratase
BTL45_RS03075	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS03080	COG1454	alcohol dehydrogenase
BTL45_RS03085	COG1024	Enoyl-CoA hydratase
BTL45_RS03105	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS03110	COG0431	NADPH-dependent FMN reductase
BTL45_RS03115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS03120	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL45_RS03135	COG1414	Transcriptional regulator
BTL45_RS03140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTL45_RS03145	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS03170	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS03175	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS03195	COG1024	Enoyl-CoA hydratase
BTL45_RS03205	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS03210	COG1024	Enoyl-CoA hydratase
BTL45_RS03215	COG0183	Belongs to the thiolase family
BTL45_RS03220	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS03235	COG0583	DNA-binding transcription factor activity
BTL45_RS03240	COG2267	carboxylic ester hydrolase activity
BTL45_RS03255	COG0625	glutathione transferase activity
BTL45_RS03260	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS03270	COG2186	Transcriptional regulator
BTL45_RS03275	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS03280	COG0626	cystathionine gamma-synthase activity
BTL45_RS03300	COG0523	cobalamin synthesis protein
BTL45_RS03320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS03325	COG0436	Aminotransferase
BTL45_RS03330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS03335	COG0765	amino acid transport
BTL45_RS03345	COG1473	amidohydrolase
BTL45_RS03350	COG1414	Transcriptional regulator
BTL45_RS03360	COG0154	amidase activity
BTL45_RS03420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS03435	COG3135	benzoate transporter
BTL45_RS03450	COG0583	DNA-binding transcription factor activity
BTL45_RS03460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL45_RS03465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS03470	COG1335	isochorismatase
BTL45_RS03520	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS03525	COG0633	Ferredoxin
BTL45_RS03525	COG0543	2 iron, 2 sulfur cluster binding
BTL45_RS03530	COG4638	Rieske (2fe-2S)
BTL45_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS03550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL45_RS03570	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS03575	COG3384	dioxygenase
BTL45_RS03585	COG3971	2-oxopent-4-enoate hydratase activity
BTL45_RS03605	COG0028	Belongs to the TPP enzyme family
BTL45_RS03640	COG1024	Enoyl-CoA hydratase
BTL45_RS03645	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS03650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS03665	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS03710	COG0183	Belongs to the thiolase family
BTL45_RS03715	COG2030	dehydratase
BTL45_RS03725	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS03765	COG1459	type II secretion system
BTL45_RS03770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTL45_RS03775	COG3267	Type II secretory pathway component ExeA
BTL45_RS03775	COG3409	Peptidoglycan-binding domain 1 protein
BTL45_RS03785	COG1450	Type ii and iii secretion system protein
BTL45_RS03850	COG5444	nuclease activity
BTL45_RS03960	COG0387	Pfam Sodium calcium exchanger
BTL45_RS03970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL45_RS04020	COG4772	TonB-dependent receptor
BTL45_RS04030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL45_RS04055	COG1054	Belongs to the UPF0176 family
BTL45_RS04060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL45_RS04060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL45_RS04070	COG0489	protein tyrosine kinase activity
BTL45_RS04115	COG2081	HI0933 family
BTL45_RS04120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTL45_RS04130	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTL45_RS04135	COG0509	glycine decarboxylation via glycine cleavage system
BTL45_RS04140	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL45_RS04140	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTL45_RS04160	COG1024	Enoyl-CoA hydratase
BTL45_RS04180	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS04185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS04190	COG0601	transmembrane transport
BTL45_RS04195	COG0747	negative chemotaxis
BTL45_RS04205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL45_RS04210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS04220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTL45_RS04235	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL45_RS04240	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL45_RS04255	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS04270	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS04275	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS04280	COG0166	Belongs to the GPI family
BTL45_RS04295	COG0277	FAD linked oxidase domain protein
BTL45_RS04300	COG0745	RESPONSE REGULATOR receiver
BTL45_RS04305	COG0642	Histidine kinase
BTL45_RS04310	COG1368	sulfuric ester hydrolase activity
BTL45_RS04320	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BTL45_RS04345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTL45_RS04355	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BTL45_RS04360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTL45_RS04390	COG0012	GTP binding
BTL45_RS04415	COG4804	nuclease activity
BTL45_RS04450	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS04455	COG1309	transcriptional regulator
BTL45_RS04465	COG2814	Major facilitator Superfamily
BTL45_RS04470	COG0280	phosphate acetyltransferase
BTL45_RS04470	COG0281	malic enzyme
BTL45_RS04480	COG0601	transmembrane transport
BTL45_RS04485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS04490	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS04495	COG0747	negative chemotaxis
BTL45_RS04505	COG0583	DNA-binding transcription factor activity
BTL45_RS04520	COG0640	Transcriptional regulator
BTL45_RS04535	COG3135	benzoate transporter
BTL45_RS04540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTL45_RS04545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BTL45_RS04550	COG0742	ribosomal rna small subunit methyltransferase
BTL45_RS04565	COG3639	organic phosphonate transmembrane transporter activity
BTL45_RS04570	COG3639	organic phosphonate transmembrane transporter activity
BTL45_RS04575	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL45_RS04600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BTL45_RS04605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL45_RS04615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTL45_RS04620	COG1546	Belongs to the CinA family
BTL45_RS04620	COG1058	Belongs to the CinA family
BTL45_RS04630	COG0284	orotidine-5'-phosphate decarboxylase activity
BTL45_RS04635	COG1252	NADH dehydrogenase
BTL45_RS04650	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS04660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTL45_RS04680	COG1053	succinate dehydrogenase
BTL45_RS04690	COG0583	DNA-binding transcription factor activity
BTL45_RS04695	COG1053	succinate dehydrogenase
BTL45_RS04700	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS04705	COG1414	Transcriptional regulator
BTL45_RS04720	COG1335	isochorismatase
BTL45_RS04735	COG0405	Gamma-glutamyltransferase
BTL45_RS04770	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS04775	COG0583	DNA-binding transcription factor activity
BTL45_RS04780	COG2199	diguanylate cyclase activity
BTL45_RS04805	COG3842	ATPase activity
BTL45_RS04830	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS04830	COG1024	Enoyl-CoA hydratase
BTL45_RS04835	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS04850	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS04860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS04865	COG0747	negative chemotaxis
BTL45_RS04885	COG2423	ornithine cyclodeaminase activity
BTL45_RS04895	COG0473	3-isopropylmalate dehydrogenase activity
BTL45_RS04900	COG0066	3-isopropylmalate dehydratase activity
BTL45_RS04905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTL45_RS04915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS04925	COG0583	DNA-binding transcription factor activity
BTL45_RS04945	COG1024	Enoyl-CoA hydratase
BTL45_RS04955	COG2084	Dehydrogenase
BTL45_RS04975	COG1850	ribulose-bisphosphate carboxylase activity
BTL45_RS04985	COG0583	DNA-binding transcription factor activity
BTL45_RS04990	COG1024	Enoyl-CoA hydratase
BTL45_RS05015	COG3842	ATPase activity
BTL45_RS05020	COG1177	transmembrane transport
BTL45_RS05035	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05040	COG3386	PFAM SMP-30 Gluconolaconase
BTL45_RS05050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL45_RS05070	COG0583	DNA-binding transcription factor activity
BTL45_RS05080	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS05095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS05135	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS05170	COG1802	Transcriptional regulator
BTL45_RS05175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS05210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05225	COG0183	Belongs to the thiolase family
BTL45_RS05230	COG1024	Enoyl-CoA hydratase
BTL45_RS05240	COG1024	Enoyl-CoA hydratase
BTL45_RS05245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05250	COG0583	DNA-binding transcription factor activity
BTL45_RS05255	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05285	COG0583	DNA-binding transcription factor activity
BTL45_RS05290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05295	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS05300	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS05340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL45_RS05385	COG0583	DNA-binding transcription factor activity
BTL45_RS05405	COG1024	Enoyl-CoA hydratase
BTL45_RS05410	COG1024	Enoyl-CoA hydratase
BTL45_RS05415	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS05420	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS05455	COG3795	YCII-related domain
BTL45_RS05460	COG2188	Transcriptional regulator
BTL45_RS05480	COG0154	amidase activity
BTL45_RS05485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05490	COG1024	Enoyl-CoA hydratase
BTL45_RS05500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS05520	COG1414	Transcriptional regulator
BTL45_RS05535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL45_RS05540	COG0251	oxidation-reduction process
BTL45_RS05545	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS05565	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS05575	COG0583	DNA-binding transcription factor activity
BTL45_RS05585	COG0590	tRNA wobble adenosine to inosine editing
BTL45_RS05590	COG2807	transmembrane transport
BTL45_RS05600	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05605	COG0154	amidase activity
BTL45_RS05610	COG0307	riboflavin synthase, alpha
BTL45_RS05615	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS05620	COG1522	sequence-specific DNA binding
BTL45_RS05630	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS05640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS05650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL45_RS05660	COG1063	alcohol dehydrogenase
BTL45_RS05680	COG1418	mRNA catabolic process
BTL45_RS05685	COG1448	Aminotransferase
BTL45_RS05690	COG0583	DNA-binding transcription factor activity
BTL45_RS05700	COG0477	Major facilitator Superfamily
BTL45_RS05705	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS05715	COG1335	isochorismatase
BTL45_RS05740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS05745	COG2274	protein secretion by the type I secretion system
BTL45_RS05755	COG1538	Outer membrane efflux protein
BTL45_RS05760	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTL45_RS05760	COG0493	'glutamate synthase
BTL45_RS05770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTL45_RS05780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS05790	COG1309	transcriptional regulator
BTL45_RS05795	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS05805	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS05810	COG2076	Multidrug Resistance protein
BTL45_RS05815	COG1309	transcriptional regulator
BTL45_RS05845	COG0840	transmembrane signaling receptor activity
BTL45_RS05870	COG0642	Histidine kinase
BTL45_RS05885	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS05895	COG4221	oxidoreductase activity
BTL45_RS05915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS05935	COG0028	Belongs to the TPP enzyme family
BTL45_RS05940	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS05950	COG1024	Enoyl-CoA hydratase
BTL45_RS05960	COG2199	diguanylate cyclase activity
BTL45_RS05960	COG2203	Gaf domain
BTL45_RS05980	COG0154	amidase activity
BTL45_RS05985	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS05985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS05995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS06010	COG3945	hemerythrin HHE cation binding domain
BTL45_RS06025	COG2169	Transcriptional regulator
BTL45_RS06025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL45_RS06045	COG1271	oxidase subunit
BTL45_RS06050	COG1294	oxidase, subunit
BTL45_RS06060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS06090	COG0596	Alpha beta hydrolase
BTL45_RS06095	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL45_RS06135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTL45_RS06140	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BTL45_RS06150	COG2070	2-Nitropropane dioxygenase
BTL45_RS06185	COG2900	Belongs to the SlyX family
BTL45_RS06195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL45_RS06220	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS06225	COG0583	DNA-binding transcription factor activity
BTL45_RS06230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS06240	COG0583	DNA-binding transcription factor activity
BTL45_RS06265	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BTL45_RS06275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL45_RS06280	COG1845	cytochrome c oxidase, subunit III
BTL45_RS06285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL45_RS06290	COG0640	Transcriptional regulator
BTL45_RS06310	COG3220	belongs to the UPF0276 family
BTL45_RS06340	COG4942	peptidase
BTL45_RS06355	COG1666	GTP binding
BTL45_RS06385	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS06395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTL45_RS06400	COG1845	cytochrome c oxidase, subunit III
BTL45_RS06405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL45_RS06410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTL45_RS06415	COG0477	Major facilitator Superfamily
BTL45_RS06430	COG5006	permease, DMT superfamily
BTL45_RS06450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTL45_RS06460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTL45_RS06465	COG3383	formate dehydrogenase (NAD+) activity
BTL45_RS06485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTL45_RS06490	COG0303	'Molybdopterin
BTL45_RS06495	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL45_RS06510	COG0315	cyclic pyranopterin monophosphate synthase activity
BTL45_RS06520	COG0412	Dienelactone hydrolase
BTL45_RS06530	COG0678	peroxiredoxin activity
BTL45_RS06540	COG0697	spore germination
BTL45_RS06585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL45_RS06590	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BTL45_RS06595	COG1335	isochorismatase
BTL45_RS06600	COG0523	cobalamin synthesis protein
BTL45_RS06620	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS06630	COG1802	Transcriptional regulator
BTL45_RS06655	COG0667	Aldo Keto reductase
BTL45_RS06660	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BTL45_RS06665	COG4535	Mg2 and Co2 transporter CorC
BTL45_RS06670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTL45_RS06675	COG1702	phosphate starvation-inducible protein PhoH
BTL45_RS06680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTL45_RS06690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL45_RS06695	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTL45_RS06700	COG1862	Preprotein translocase
BTL45_RS06705	COG0343	queuine tRNA-ribosyltransferase activity
BTL45_RS06710	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BTL45_RS06715	COG2027	D-alanyl-D-alanine carboxypeptidase
BTL45_RS06730	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS06760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTL45_RS06765	COG0741	lytic transglycosylase activity
BTL45_RS06770	COG0436	Aminotransferase
BTL45_RS06780	COG0280	phosphate acetyltransferase
BTL45_RS06780	COG0281	malic enzyme
BTL45_RS06790	COG2732	(Barnase) inhibitor
BTL45_RS06795	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTL45_RS06800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTL45_RS06805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTL45_RS06810	COG0126	phosphoglycerate kinase activity
BTL45_RS06815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTL45_RS06820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BTL45_RS06835	COG0625	glutathione transferase activity
BTL45_RS06865	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BTL45_RS06875	COG0306	phosphate transporter
BTL45_RS06880	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTL45_RS06890	COG0739	heme binding
BTL45_RS06900	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTL45_RS06950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTL45_RS06960	COG2944	sequence-specific DNA binding
BTL45_RS06970	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BTL45_RS06975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTL45_RS06980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTL45_RS06985	COG0009	L-threonylcarbamoyladenylate synthase
BTL45_RS06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS06995	COG1414	Transcriptional regulator
BTL45_RS07010	COG0765	amino acid transport
BTL45_RS07015	COG1126	abc transporter atp-binding protein
BTL45_RS07020	COG0028	Belongs to the TPP enzyme family
BTL45_RS07035	COG0028	Belongs to the TPP enzyme family
BTL45_RS07040	COG0583	DNA-binding transcription factor activity
BTL45_RS07045	COG4974	Belongs to the 'phage' integrase family
BTL45_RS07050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTL45_RS07055	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BTL45_RS07065	COG1686	Belongs to the peptidase S11 family
BTL45_RS07075	COG2814	Major facilitator Superfamily
BTL45_RS07085	COG1074	ATP-dependent DNA helicase activity
BTL45_RS07100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BTL45_RS07115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS07120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL45_RS07130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS07135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTL45_RS07140	COG0505	Belongs to the CarA family
BTL45_RS07145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTL45_RS07150	COG4221	oxidoreductase activity
BTL45_RS07155	COG0406	alpha-ribazole phosphatase activity
BTL45_RS07165	COG3842	ATPase activity
BTL45_RS07185	COG2233	PERMEase
BTL45_RS07190	COG0840	transmembrane signaling receptor activity
BTL45_RS07195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTL45_RS07200	COG1534	Rna-binding protein
BTL45_RS07210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL45_RS07220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTL45_RS07230	COG0248	Ppx GppA phosphatase
BTL45_RS07330	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS07360	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS07380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS07430	COG1137	ATPase activity
BTL45_RS07440	COG0154	amidase activity
BTL45_RS07445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS07470	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS07475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS07480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS07490	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL45_RS07500	COG1522	sequence-specific DNA binding
BTL45_RS07505	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL45_RS07510	COG1473	amidohydrolase
BTL45_RS07515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS07520	COG4597	amino acid ABC transporter
BTL45_RS07525	COG0765	amino acid transport
BTL45_RS07530	COG1126	abc transporter atp-binding protein
BTL45_RS07545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL45_RS07590	COG2985	domain, Protein
BTL45_RS07595	COG0583	DNA-binding transcription factor activity
BTL45_RS07630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTL45_RS07665	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BTL45_RS07675	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL45_RS07695	COG1132	(ABC) transporter
BTL45_RS07700	COG0500	methyltransferase
BTL45_RS07720	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BTL45_RS07730	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS07740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTL45_RS07750	COG0511	ligase activity, forming carbon-carbon bonds
BTL45_RS07775	COG2188	Transcriptional regulator
BTL45_RS07780	COG0439	Biotin carboxylase
BTL45_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
BTL45_RS07800	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL45_RS07800	COG1042	CoA-binding domain protein
BTL45_RS07800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTL45_RS07805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS07835	COG3971	2-oxopent-4-enoate hydratase activity
BTL45_RS07840	COG0583	DNA-binding transcription factor activity
BTL45_RS07855	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL45_RS07895	COG1129	ABC transporter
BTL45_RS07905	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS07930	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS07935	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS07940	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTL45_RS07945	COG0583	DNA-binding transcription factor activity
BTL45_RS07950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS07975	COG0251	oxidation-reduction process
BTL45_RS07980	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS08010	COG4789	Type iii secretion
BTL45_RS08075	COG4669	(LipO)protein
BTL45_RS08110	COG4790	Type iii secretion
BTL45_RS08115	COG4794	Type iii secretion
BTL45_RS08120	COG4791	protein targeting
BTL45_RS08125	COG4792	protein secretion
BTL45_RS08140	COG1595	DNA-templated transcription, initiation
BTL45_RS08160	COG2208	phosphoserine phosphatase activity
BTL45_RS08160	COG2770	Histidine kinase
BTL45_RS08170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTL45_RS08175	COG2172	sigma factor antagonist activity
BTL45_RS08180	COG1366	Belongs to the anti-sigma-factor antagonist family
BTL45_RS08185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL45_RS08230	COG2321	neutral zinc metallopeptidase
BTL45_RS08235	COG0009	L-threonylcarbamoyladenylate synthase
BTL45_RS08240	COG1994	Peptidase M50
BTL45_RS08245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS08250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BTL45_RS08255	COG3539	Fimbrial protein
BTL45_RS08265	COG2850	peptidyl-arginine hydroxylation
BTL45_RS08275	COG3360	Dodecin
BTL45_RS08310	COG0668	transmembrane transport
BTL45_RS08330	COG0483	inositol monophosphate 1-phosphatase activity
BTL45_RS08335	COG1253	flavin adenine dinucleotide binding
BTL45_RS08345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL45_RS08360	COG0215	cysteine-tRNA ligase activity
BTL45_RS08370	COG0825	malonyl-CoA metabolic process
BTL45_RS08375	COG0037	tRNA processing
BTL45_RS08380	COG0527	aspartate kinase activity
BTL45_RS08400	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS08405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS08405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS08420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL45_RS08425	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BTL45_RS08430	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS08440	COG0583	DNA-binding transcription factor activity
BTL45_RS08465	COG3842	ATPase activity
BTL45_RS08475	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTL45_RS08475	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS08480	COG1414	Transcriptional regulator
BTL45_RS08485	COG1832	CoA-binding protein
BTL45_RS08495	COG0251	oxidation-reduction process
BTL45_RS08520	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS08530	COG1215	transferase activity, transferring glycosyl groups
BTL45_RS08535	COG0726	polysaccharide deacetylase
BTL45_RS08535	COG1649	PFAM Uncharacterised BCR, COG1649
BTL45_RS08555	COG1846	Transcriptional regulator
BTL45_RS08585	COG2010	Cytochrome c
BTL45_RS08585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BTL45_RS08590	COG2080	2 iron, 2 sulfur cluster binding
BTL45_RS08595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL45_RS08600	COG3473	Maleate cis-trans isomerase
BTL45_RS08605	COG0596	Alpha beta hydrolase
BTL45_RS08610	COG2309	aminopeptidase activity
BTL45_RS08615	COG1335	isochorismatase
BTL45_RS08620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BTL45_RS08620	COG2010	Cytochrome c
BTL45_RS08625	COG1017	nitric oxide dioxygenase activity
BTL45_RS08625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL45_RS08640	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS08650	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS08660	COG0183	Belongs to the thiolase family
BTL45_RS08665	COG1024	Enoyl-CoA hydratase
BTL45_RS08665	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS08680	COG0183	Belongs to the thiolase family
BTL45_RS08695	COG2197	response regulator
BTL45_RS08710	COG0166	Belongs to the GPI family
BTL45_RS08715	COG1045	serine acetyltransferase
BTL45_RS08725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BTL45_RS08730	COG0483	inositol monophosphate 1-phosphatase activity
BTL45_RS08740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTL45_RS08755	COG0210	DNA helicase
BTL45_RS08760	COG0598	Magnesium transport protein CorA
BTL45_RS08770	COG0747	negative chemotaxis
BTL45_RS08775	COG0601	transmembrane transport
BTL45_RS08780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS08785	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS08790	COG1846	Transcriptional regulator
BTL45_RS08835	COG4964	Belongs to the GSP D family
BTL45_RS08875	COG2204	response regulator
BTL45_RS08900	COG3474	cytochrome
BTL45_RS08905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTL45_RS08920	COG3384	dioxygenase
BTL45_RS08925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTL45_RS08945	COG2885	chlorophyll binding
BTL45_RS08980	COG0697	spore germination
BTL45_RS08985	COG0730	response to heat
BTL45_RS09000	COG3264	Mechanosensitive ion channel
BTL45_RS09000	COG1511	domain protein
BTL45_RS09005	COG0583	DNA-binding transcription factor activity
BTL45_RS09010	COG0427	acetyl-CoA hydrolase
BTL45_RS09015	COG0385	Bile acid
BTL45_RS09065	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS09070	COG0154	amidase activity
BTL45_RS09080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTL45_RS09095	COG0495	leucyl-tRNA aminoacylation
BTL45_RS09100	COG2814	Major facilitator Superfamily
BTL45_RS09120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTL45_RS09125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTL45_RS09130	COG2814	Major facilitator Superfamily
BTL45_RS09135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTL45_RS09145	COG4176	ABC-type proline glycine betaine transport system permease component
BTL45_RS09155	COG1942	4-Oxalocrotonate Tautomerase
BTL45_RS09160	COG0183	Belongs to the thiolase family
BTL45_RS09170	COG1802	Transcriptional regulator
BTL45_RS09180	COG1024	Enoyl-CoA hydratase
BTL45_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS09195	COG2032	superoxide dismutase activity
BTL45_RS09210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTL45_RS09235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS09240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL45_RS09250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BTL45_RS09255	COG0736	holo-[acyl-carrier-protein] synthase activity
BTL45_RS09265	COG0322	excinuclease ABC activity
BTL45_RS09270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTL45_RS09280	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL45_RS09280	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTL45_RS09285	COG2224	Isocitrate lyase
BTL45_RS09295	COG1346	cytolysis
BTL45_RS09300	COG1380	Effector of murein hydrolase LrgA
BTL45_RS09305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BTL45_RS09305	COG4106	trans-aconitate 2-methyltransferase activity
BTL45_RS09315	COG0156	8-amino-7-oxononanoate synthase activity
BTL45_RS09335	COG3278	Belongs to the heme-copper respiratory oxidase family
BTL45_RS09380	COG1131	(ABC) transporter
BTL45_RS09385	COG0842	Transport permease protein
BTL45_RS09390	COG0628	permease
BTL45_RS09405	COG2814	Major facilitator Superfamily
BTL45_RS09410	COG2841	Protein conserved in bacteria
BTL45_RS09435	COG0765	amino acid transport
BTL45_RS09440	COG0765	amino acid transport
BTL45_RS09445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS09480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS09485	COG1595	DNA-templated transcription, initiation
BTL45_RS09495	COG3530	Putative quorum-sensing-regulated virulence factor
BTL45_RS09500	COG0494	nUDIX hydrolase
BTL45_RS09515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTL45_RS09520	COG0542	response to heat
BTL45_RS09525	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS09540	COG5441	Belongs to the UPF0261 family
BTL45_RS09545	COG5564	TIM-barrel signal transduction protein
BTL45_RS09560	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BTL45_RS09575	COG1477	protein flavinylation
BTL45_RS09595	COG1131	(ABC) transporter
BTL45_RS09600	COG0842	Transport permease protein
BTL45_RS09610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BTL45_RS09615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL45_RS09615	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BTL45_RS09620	COG1562	ergosterol biosynthetic process
BTL45_RS09625	COG1562	ergosterol biosynthetic process
BTL45_RS09630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTL45_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS09650	COG2304	oxidoreductase activity
BTL45_RS09670	COG0534	Mate efflux family protein
BTL45_RS09680	COG0254	rRNA binding
BTL45_RS09685	COG3483	tryptophan 2,3-dioxygenase activity
BTL45_RS09690	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BTL45_RS09695	COG2003	Belongs to the UPF0758 family
BTL45_RS09700	COG1047	Peptidyl-prolyl cis-trans
BTL45_RS09705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BTL45_RS09710	COG0625	glutathione transferase activity
BTL45_RS09730	COG0523	cobalamin synthesis protein
BTL45_RS09740	COG0583	DNA-binding transcription factor activity
BTL45_RS09750	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BTL45_RS09755	COG1187	pseudouridine synthase activity
BTL45_RS09760	COG0779	Required for maturation of 30S ribosomal subunits
BTL45_RS09765	COG0195	Participates in both transcription termination and antitermination
BTL45_RS09765	COG2251	uridine kinase activity
BTL45_RS09770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTL45_RS09775	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTL45_RS09780	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTL45_RS09800	COG1611	Belongs to the LOG family
BTL45_RS09815	COG0412	Dienelactone hydrolase
BTL45_RS09820	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTL45_RS09825	COG1760	l-serine dehydratase
BTL45_RS09830	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTL45_RS09845	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTL45_RS09870	COG2311	Membrane
BTL45_RS09880	COG2358	TRAP transporter, solute receptor (TAXI family
BTL45_RS09885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL45_RS09900	COG0456	acetyltransferase
BTL45_RS09915	COG5285	phytanoyl-CoA dioxygenase
BTL45_RS09925	COG3395	kinase activity
BTL45_RS09930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTL45_RS09945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BTL45_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS09980	COG0747	negative chemotaxis
BTL45_RS09985	COG0601	transmembrane transport
BTL45_RS09990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS09995	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS10045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTL45_RS10050	COG0425	Belongs to the sulfur carrier protein TusA family
BTL45_RS10060	COG0228	four-way junction DNA binding
BTL45_RS10070	COG0336	Belongs to the RNA methyltransferase TrmD family
BTL45_RS10075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTL45_RS10085	COG0642	Histidine kinase
BTL45_RS10100	COG0525	valine-tRNA ligase activity
BTL45_RS10105	COG0105	UTP biosynthetic process
BTL45_RS10110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTL45_RS10130	COG2976	Protein conserved in bacteria
BTL45_RS10135	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL45_RS10140	COG1160	GTP binding
BTL45_RS10145	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTL45_RS10150	COG1923	regulation of RNA biosynthetic process
BTL45_RS10155	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTL45_RS10160	COG0330	HflC and HflK could
BTL45_RS10165	COG0330	HflC and HflK could
BTL45_RS10175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTL45_RS10180	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BTL45_RS10185	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTL45_RS10195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTL45_RS10265	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS10275	COG4638	Rieske (2fe-2S)
BTL45_RS10285	COG1024	Enoyl-CoA hydratase
BTL45_RS10295	COG0633	Ferredoxin
BTL45_RS10300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS10315	COG0183	Belongs to the thiolase family
BTL45_RS10330	COG0583	DNA-binding transcription factor activity
BTL45_RS10345	COG0028	Belongs to the TPP enzyme family
BTL45_RS10350	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS10355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS10390	COG3829	transcription factor binding
BTL45_RS10420	COG0833	amino acid
BTL45_RS10435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL45_RS10440	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BTL45_RS10445	COG0840	transmembrane signaling receptor activity
BTL45_RS10475	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS10480	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS10515	COG5265	(ABC) transporter
BTL45_RS10525	COG0667	Aldo Keto reductase
BTL45_RS10540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BTL45_RS10580	COG1959	2 iron, 2 sulfur cluster binding
BTL45_RS10585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS10590	COG0587	DNA-directed DNA polymerase activity
BTL45_RS10605	COG0400	carboxylic ester hydrolase activity
BTL45_RS10615	COG1566	PFAM secretion protein HlyD family protein
BTL45_RS10640	COG0235	Class ii aldolase
BTL45_RS10645	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS10650	COG0720	synthase
BTL45_RS10655	COG0602	queuosine metabolic process
BTL45_RS10680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS10720	COG3842	ATPase activity
BTL45_RS10730	COG0395	ABC-type sugar transport system, permease component
BTL45_RS10760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS10765	COG0420	3'-5' exonuclease activity
BTL45_RS10775	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS10780	COG2111	Na H antiporter
BTL45_RS10780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTL45_RS10785	COG1006	Multisubunit Na H antiporter MnhC subunit
BTL45_RS10790	COG0651	ATP synthesis coupled electron transport
BTL45_RS10795	COG1863	multisubunit Na H antiporter MnhE subunit
BTL45_RS10800	COG2212	antiporter activity
BTL45_RS10820	COG0590	tRNA wobble adenosine to inosine editing
BTL45_RS10825	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL45_RS10830	COG1024	Enoyl-CoA hydratase
BTL45_RS10835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS10845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS10850	COG0488	(ABC) transporter
BTL45_RS10880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL45_RS10885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BTL45_RS10890	COG2252	PERMEase
BTL45_RS10895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BTL45_RS10900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTL45_RS10905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BTL45_RS10935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTL45_RS10940	COG0789	Transcriptional regulator
BTL45_RS10950	COG0678	peroxiredoxin activity
BTL45_RS10950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTL45_RS10960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTL45_RS10965	COG0584	glycerophosphoryl diester phosphodiesterase
BTL45_RS10970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL45_RS10980	COG4181	ATPase activity
BTL45_RS11005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS11020	COG4336	lyase activity
BTL45_RS11030	COG2205	protein histidine kinase activity
BTL45_RS11030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS11035	COG2197	response regulator
BTL45_RS11040	COG3210	domain, Protein
BTL45_RS11040	COG3064	Membrane
BTL45_RS11040	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL45_RS11050	COG3121	Chaperone
BTL45_RS11055	COG3188	usher protein
BTL45_RS11060	COG3539	Fimbrial protein
BTL45_RS11065	COG2831	hemolysin activation secretion protein
BTL45_RS11080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS11105	COG0583	DNA-binding transcription factor activity
BTL45_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS11130	COG0765	amino acid transport
BTL45_RS11135	COG1126	abc transporter atp-binding protein
BTL45_RS11140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL45_RS11145	COG1758	RNA polymerase activity
BTL45_RS11150	COG0194	GDP metabolic process
BTL45_RS11155	COG3258	Cytochrome c
BTL45_RS11160	COG2863	cytochrome
BTL45_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS11170	COG0791	NLP P60 protein
BTL45_RS11175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTL45_RS11190	COG1561	YicC-like family, N-terminal region
BTL45_RS11195	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BTL45_RS11210	COG0840	transmembrane signaling receptor activity
BTL45_RS11215	COG5002	protein histidine kinase activity
BTL45_RS11215	COG5001	Diguanylate cyclase
BTL45_RS11220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTL45_RS11225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL45_RS11230	COG0174	glutamine synthetase
BTL45_RS11240	COG2204	response regulator
BTL45_RS11245	COG0583	DNA-binding transcription factor activity
BTL45_RS11250	COG1741	Belongs to the pirin family
BTL45_RS11255	COG1741	Belongs to the pirin family
BTL45_RS11260	COG3842	ATPase activity
BTL45_RS11265	COG1178	ABC-type Fe3 transport system permease component
BTL45_RS11270	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL45_RS11290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTL45_RS11295	COG0583	DNA-binding transcription factor activity
BTL45_RS11310	COG0783	Belongs to the Dps family
BTL45_RS11325	COG0463	Glycosyl transferase, family 2
BTL45_RS11345	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS11360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BTL45_RS11380	COG0300	oxidoreductase activity
BTL45_RS11390	COG0156	8-amino-7-oxononanoate synthase activity
BTL45_RS11395	COG3321	synthase
BTL45_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS11395	COG0604	alcohol dehydrogenase
BTL45_RS11410	COG3842	ATPase activity
BTL45_RS11415	COG0395	ABC-type sugar transport system, permease component
BTL45_RS11420	COG1175	transmembrane transport
BTL45_RS11425	COG1653	transport
BTL45_RS11435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BTL45_RS11445	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS11465	COG1794	racemase activity, acting on amino acids and derivatives
BTL45_RS11470	COG0625	glutathione transferase activity
BTL45_RS11475	COG2133	pyrroloquinoline quinone binding
BTL45_RS11485	COG0697	spore germination
BTL45_RS11490	COG2363	Small membrane protein
BTL45_RS11505	COG1464	Belongs to the NlpA lipoprotein family
BTL45_RS11515	COG0688	phosphatidylethanolamine metabolic process
BTL45_RS11530	COG0095	Lipoate-protein ligase
BTL45_RS11545	COG0625	glutathione transferase activity
BTL45_RS11550	COG0386	Belongs to the glutathione peroxidase family
BTL45_RS11570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS11580	COG1629	transport
BTL45_RS11580	COG4771	TonB-dependent receptor
BTL45_RS11595	COG2259	Doxx family
BTL45_RS11610	COG0667	Aldo Keto reductase
BTL45_RS11660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BTL45_RS11670	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BTL45_RS11680	COG0366	Alpha amylase catalytic
BTL45_RS11685	COG0297	glycogen (starch) synthase activity
BTL45_RS11695	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTL45_RS11700	COG2204	response regulator
BTL45_RS11705	COG2204	response regulator
BTL45_RS11710	COG0028	Belongs to the TPP enzyme family
BTL45_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS11770	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BTL45_RS11775	COG4575	ribosome binding
BTL45_RS11810	COG0392	lysyltransferase activity
BTL45_RS11815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL45_RS11820	COG3568	Endonuclease Exonuclease Phosphatase
BTL45_RS11830	COG1695	Transcriptional regulator
BTL45_RS11835	COG2375	cellular response to nickel ion
BTL45_RS11840	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS11850	COG0583	DNA-binding transcription factor activity
BTL45_RS11865	COG1802	Transcriptional regulator
BTL45_RS11875	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS11885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS11890	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS11900	COG0066	3-isopropylmalate dehydratase activity
BTL45_RS11905	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTL45_RS11910	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS11915	COG4948	Mandelate Racemase Muconate Lactonizing
BTL45_RS11945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL45_RS11955	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BTL45_RS11975	COG4133	protoheme IX ABC transporter activity
BTL45_RS11980	COG3005	denitrification pathway
BTL45_RS11985	COG3043	anaerobic respiration
BTL45_RS12005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS12010	COG0765	amino acid transport
BTL45_RS12015	COG1126	abc transporter atp-binding protein
BTL45_RS12020	COG0330	HflC and HflK could
BTL45_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS12030	COG1454	alcohol dehydrogenase
BTL45_RS12035	COG4251	negative regulation of phosphorylation
BTL45_RS12035	COG3706	GGDEF domain
BTL45_RS12035	COG2203	Gaf domain
BTL45_RS12035	COG5001	Diguanylate cyclase
BTL45_RS12045	COG0583	DNA-binding transcription factor activity
BTL45_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS12080	COG0431	NADPH-dependent FMN reductase
BTL45_RS12085	COG0583	DNA-binding transcription factor activity
BTL45_RS12105	COG0824	Thioesterase
BTL45_RS12110	COG1454	alcohol dehydrogenase
BTL45_RS12115	COG0183	Belongs to the thiolase family
BTL45_RS12120	COG1024	Enoyl-CoA hydratase
BTL45_RS12120	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS12125	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS12135	COG1024	Enoyl-CoA hydratase
BTL45_RS12140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS12145	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS12150	COG0583	DNA-binding transcription factor activity
BTL45_RS12170	COG0183	Belongs to the thiolase family
BTL45_RS12175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS12180	COG1414	Transcriptional regulator
BTL45_RS12185	COG1309	transcriptional regulator
BTL45_RS12230	COG3119	arylsulfatase activity
BTL45_RS12260	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL45_RS12265	COG1304	FMN binding
BTL45_RS12290	COG0625	glutathione transferase activity
BTL45_RS12300	COG2197	response regulator
BTL45_RS12315	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS12320	COG0861	Integral membrane protein TerC family
BTL45_RS12350	COG1228	amidohydrolase
BTL45_RS12360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL45_RS12370	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS12390	COG0583	DNA-binding transcription factor activity
BTL45_RS12395	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS12420	COG2188	Transcriptional regulator
BTL45_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS12435	COG1414	Transcriptional regulator
BTL45_RS12440	COG3842	ATPase activity
BTL45_RS12450	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTL45_RS12455	COG0395	ABC-type sugar transport system, permease component
BTL45_RS12470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS12485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTL45_RS12490	COG0439	Biotin carboxylase
BTL45_RS12495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BTL45_RS12500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS12515	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS12525	COG0583	DNA-binding transcription factor activity
BTL45_RS12535	COG2814	Major facilitator Superfamily
BTL45_RS12550	COG1619	proteins homologs of microcin C7 resistance protein MccF
BTL45_RS12565	COG2084	Dehydrogenase
BTL45_RS12570	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS12580	COG1253	flavin adenine dinucleotide binding
BTL45_RS12595	COG2988	succinylglutamate desuccinylase activity
BTL45_RS12620	COG0861	Integral membrane protein TerC family
BTL45_RS12630	COG1595	DNA-templated transcription, initiation
BTL45_RS12645	COG0076	glutamate decarboxylase activity
BTL45_RS12650	COG2985	domain, Protein
BTL45_RS12655	COG2010	Cytochrome c
BTL45_RS12660	COG3189	MarR family transcriptional regulator
BTL45_RS12670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS12680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS12680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS12690	COG0028	Belongs to the TPP enzyme family
BTL45_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS12705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL45_RS12710	COG0010	Belongs to the arginase family
BTL45_RS12715	COG1126	abc transporter atp-binding protein
BTL45_RS12720	COG0765	amino acid transport
BTL45_RS12725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS12740	COG0084	hydrolase, TatD family'
BTL45_RS12750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTL45_RS12755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTL45_RS12780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BTL45_RS12785	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS12795	COG2867	negative regulation of translational initiation
BTL45_RS12800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BTL45_RS12805	COG3706	GGDEF domain
BTL45_RS12810	COG0330	HflC and HflK could
BTL45_RS12820	COG0519	Catalyzes the synthesis of GMP from XMP
BTL45_RS12820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL45_RS12835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL45_RS12840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTL45_RS12855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTL45_RS12860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTL45_RS12865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BTL45_RS12870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL45_RS12875	COG0750	zinc metalloprotease
BTL45_RS12880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BTL45_RS12885	COG0575	Belongs to the CDS family
BTL45_RS12890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTL45_RS12895	COG0233	cytoplasmic translational termination
BTL45_RS12900	COG0528	UMP kinase activity
BTL45_RS12905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTL45_RS12910	COG0052	Belongs to the universal ribosomal protein uS2 family
BTL45_RS12915	COG0024	Methionine aminopeptidase
BTL45_RS12920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BTL45_RS12950	COG0285	dihydrofolate synthase activity
BTL45_RS12980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BTL45_RS12990	COG1677	Flagellar hook-basal body complex protein FliE
BTL45_RS13000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL45_RS13010	COG1157	protein secretion by the type III secretion system
BTL45_RS13025	COG1580	Controls the rotational direction of flagella during chemotaxis
BTL45_RS13035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTL45_RS13045	COG1338	Plays a role in the flagellum-specific transport system
BTL45_RS13060	COG0840	transmembrane signaling receptor activity
BTL45_RS13075	COG0840	transmembrane signaling receptor activity
BTL45_RS13080	COG0840	transmembrane signaling receptor activity
BTL45_RS13090	COG1256	bacterial-type flagellum assembly
BTL45_RS13105	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BTL45_RS13120	COG1749	Flagellar hook protein flgE
BTL45_RS13130	COG1558	bacterial-type flagellum-dependent cell motility
BTL45_RS13135	COG1815	bacterial-type flagellum-dependent cell motility
BTL45_RS13170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BTL45_RS13175	COG0745	RESPONSE REGULATOR receiver
BTL45_RS13180	COG2201	protein-glutamate methylesterase activity
BTL45_RS13185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTL45_RS13190	COG0840	transmembrane signaling receptor activity
BTL45_RS13200	COG0643	Histidine kinase
BTL45_RS13200	COG2198	Histidine kinase
BTL45_RS13205	COG0745	RESPONSE REGULATOR receiver
BTL45_RS13240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTL45_RS13245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL45_RS13250	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL45_RS13255	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTL45_RS13265	COG4566	intracellular signal transduction
BTL45_RS13270	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTL45_RS13275	COG0339	signal peptide processing
BTL45_RS13280	COG1999	signal sequence binding
BTL45_RS13300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS13310	COG1187	pseudouridine synthase activity
BTL45_RS13315	COG3161	chorismate lyase activity
BTL45_RS13320	COG2814	Major facilitator Superfamily
BTL45_RS13330	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS13335	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS13340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS13345	COG0601	transmembrane transport
BTL45_RS13350	COG0747	negative chemotaxis
BTL45_RS13395	COG0668	transmembrane transport
BTL45_RS13400	COG0165	Argininosuccinate lyase
BTL45_RS13410	COG0789	Transcriptional regulator
BTL45_RS13420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS13425	COG0765	amino acid transport
BTL45_RS13430	COG1126	abc transporter atp-binding protein
BTL45_RS13440	COG2346	COG2346, Truncated hemoglobins
BTL45_RS13500	COG1335	isochorismatase
BTL45_RS13505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS13525	COG2837	iron assimilation
BTL45_RS13555	COG4691	Plasmid stability protein
BTL45_RS13590	COG0583	DNA-binding transcription factor activity
BTL45_RS13595	COG2814	Major facilitator Superfamily
BTL45_RS13605	COG0501	Belongs to the peptidase M48B family
BTL45_RS13615	COG0583	DNA-binding transcription factor activity
BTL45_RS13625	COG2188	Transcriptional regulator
BTL45_RS13640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTL45_RS13650	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS13655	COG0129	dihydroxy-acid dehydratase activity
BTL45_RS13670	COG0129	dihydroxy-acid dehydratase activity
BTL45_RS13680	COG3622	Belongs to the hyi family
BTL45_RS13685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL45_RS13690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS13705	COG0583	DNA-binding transcription factor activity
BTL45_RS13710	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS13715	COG3246	L-lysine catabolic process to acetate
BTL45_RS13730	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BTL45_RS13735	COG0534	Mate efflux family protein
BTL45_RS13750	COG0697	spore germination
BTL45_RS13765	COG0625	glutathione transferase activity
BTL45_RS13785	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS13790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL45_RS13825	COG2207	Transcriptional regulator
BTL45_RS13865	COG1132	(ABC) transporter
BTL45_RS13890	COG0659	secondary active sulfate transmembrane transporter activity
BTL45_RS13920	COG2169	Transcriptional regulator
BTL45_RS13925	COG5507	3-demethylubiquinone-9 3-methyltransferase
BTL45_RS13930	COG0384	phenazine biosynthesis protein PhzF
BTL45_RS13935	COG0583	DNA-binding transcription factor activity
BTL45_RS13940	COG2733	membrane
BTL45_RS13955	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS13960	COG3284	Transcriptional regulator
BTL45_RS13965	COG0656	L-ascorbic acid biosynthetic process
BTL45_RS13985	COG1131	(ABC) transporter
BTL45_RS13990	COG0842	Transport permease protein
BTL45_RS13995	COG0842	Transport permease protein
BTL45_RS14010	COG1802	Transcriptional regulator
BTL45_RS14030	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS14035	COG2188	Transcriptional regulator
BTL45_RS14060	COG0789	Transcriptional regulator
BTL45_RS14075	COG1609	Transcriptional regulator
BTL45_RS14080	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS14085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS14090	COG0601	transmembrane transport
BTL45_RS14095	COG0747	negative chemotaxis
BTL45_RS14110	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS14130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BTL45_RS14155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS14160	COG1116	anion transmembrane transporter activity
BTL45_RS14170	COG1228	amidohydrolase
BTL45_RS14175	COG1414	Transcriptional regulator
BTL45_RS14185	COG0477	Major facilitator Superfamily
BTL45_RS14195	COG3550	peptidyl-serine autophosphorylation
BTL45_RS14225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTL45_RS14265	COG0798	PFAM Bile acid sodium symporter
BTL45_RS14300	COG4691	Plasmid stability protein
BTL45_RS14325	COG0519	Catalyzes the synthesis of GMP from XMP
BTL45_RS14325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTL45_RS14360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL45_RS14375	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS14395	COG3064	Membrane
BTL45_RS14395	COG3210	domain, Protein
BTL45_RS14395	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL45_RS14400	COG0047	phosphoribosylformylglycinamidine synthase activity
BTL45_RS14400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTL45_RS14405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS14410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS14410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS14415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS14425	COG0613	PHP domain protein
BTL45_RS14435	COG0658	competence protein
BTL45_RS14435	COG2333	competence protein COMEC
BTL45_RS14445	COG0084	hydrolase, TatD family'
BTL45_RS14450	COG1136	(ABC) transporter
BTL45_RS14465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTL45_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS14480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BTL45_RS14495	COG1022	Amp-dependent synthetase and ligase
BTL45_RS14525	COG1024	Enoyl-CoA hydratase
BTL45_RS14540	COG0633	Ferredoxin
BTL45_RS14545	COG0443	Heat shock 70 kDa protein
BTL45_RS14555	COG0316	Belongs to the HesB IscA family
BTL45_RS14560	COG0822	iron-sulfur transferase activity
BTL45_RS14565	COG1104	cysteine desulfurase activity
BTL45_RS14575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTL45_RS14580	COG0556	nucleotide-excision repair
BTL45_RS14595	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS14605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BTL45_RS14620	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS14630	COG0183	Belongs to the thiolase family
BTL45_RS14640	COG1024	Enoyl-CoA hydratase
BTL45_RS14655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS14660	COG0583	DNA-binding transcription factor activity
BTL45_RS14665	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTL45_RS14675	COG0740	serine-type endopeptidase activity
BTL45_RS14680	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTL45_RS14690	COG1278	Cold shock
BTL45_RS14700	COG1278	Cold shock
BTL45_RS14730	COG0436	Aminotransferase
BTL45_RS14735	COG2171	N-acyltransferase activity
BTL45_RS14745	COG2890	protein-(glutamine-N5) methyltransferase activity
BTL45_RS14750	COG0488	(ABC) transporter
BTL45_RS14755	COG4771	TonB-dependent receptor
BTL45_RS14760	COG0210	DNA helicase
BTL45_RS14775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTL45_RS14775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTL45_RS14780	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTL45_RS14785	COG0196	riboflavin kinase activity
BTL45_RS14790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTL45_RS14795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BTL45_RS14800	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTL45_RS14810	COG1522	sequence-specific DNA binding
BTL45_RS14820	COG0586	Pfam SNARE associated Golgi protein
BTL45_RS14830	COG0756	dUTP diphosphatase activity
BTL45_RS14835	COG1126	abc transporter atp-binding protein
BTL45_RS14840	COG0765	amino acid transport
BTL45_RS14845	COG0765	amino acid transport
BTL45_RS14850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS14860	COG2423	ornithine cyclodeaminase activity
BTL45_RS14865	COG1764	response to oxidative stress
BTL45_RS14875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTL45_RS14880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTL45_RS14895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTL45_RS14900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTL45_RS14905	COG2197	response regulator
BTL45_RS14915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTL45_RS14965	COG0135	phosphoribosylanthranilate isomerase activity
BTL45_RS14980	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS14985	COG0101	tRNA pseudouridine synthase activity
BTL45_RS14995	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTL45_RS15020	COG1122	ATPase activity
BTL45_RS15050	COG0437	4 iron, 4 sulfur cluster binding
BTL45_RS15055	COG0243	molybdopterin cofactor binding
BTL45_RS15055	COG3383	formate dehydrogenase (NAD+) activity
BTL45_RS15085	COG0489	protein tyrosine kinase activity
BTL45_RS15090	COG0746	molybdenum cofactor guanylyltransferase activity
BTL45_RS15095	COG0303	'Molybdopterin
BTL45_RS15100	COG1763	Mo-molybdopterin cofactor biosynthetic process
BTL45_RS15110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTL45_RS15115	COG5001	Diguanylate cyclase
BTL45_RS15115	COG3300	MHYT domain
BTL45_RS15120	COG2205	protein histidine kinase activity
BTL45_RS15125	COG0745	RESPONSE REGULATOR receiver
BTL45_RS15140	COG1295	ribonuclease BN
BTL45_RS15150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTL45_RS15185	COG4964	Belongs to the GSP D family
BTL45_RS15245	COG0181	hydroxymethylbilane synthase activity
BTL45_RS15250	COG0861	Integral membrane protein TerC family
BTL45_RS15255	COG0861	Integral membrane protein TerC family
BTL45_RS15260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BTL45_RS15265	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL45_RS15285	COG2137	regulation of response to DNA damage stimulus
BTL45_RS15290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTL45_RS15310	COG1024	Enoyl-CoA hydratase
BTL45_RS15310	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS15315	COG3842	ATPase activity
BTL45_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS15345	COG0183	Belongs to the thiolase family
BTL45_RS15350	COG0583	DNA-binding transcription factor activity
BTL45_RS15355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS15365	COG2974	May be involved in recombination
BTL45_RS15370	COG0540	Belongs to the ATCase OTCase family
BTL45_RS15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS15420	COG1522	sequence-specific DNA binding
BTL45_RS15430	COG2367	Beta-lactamase
BTL45_RS15445	COG0500	methyltransferase
BTL45_RS15480	COG0072	phenylalanine-tRNA ligase activity
BTL45_RS15480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTL45_RS15485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTL45_RS15490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTL45_RS15495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTL45_RS15515	COG0004	ammonium transporteR
BTL45_RS15525	COG1309	transcriptional regulator
BTL45_RS15530	COG2271	Major facilitator Superfamily
BTL45_RS15560	COG0506	proline dehydrogenase activity
BTL45_RS15560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL45_RS15560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BTL45_RS15570	COG3008	intermembrane lipid transfer
BTL45_RS15570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTL45_RS15575	COG2995	paraquat-inducible protein a
BTL45_RS15580	COG0542	response to heat
BTL45_RS15585	COG4953	penicillin-binding protein 1C
BTL45_RS15595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BTL45_RS15600	COG1278	Cold shock
BTL45_RS15610	COG0183	Belongs to the thiolase family
BTL45_RS15615	COG0038	chloride channel
BTL45_RS15620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTL45_RS15630	COG0811	peptide transport
BTL45_RS15635	COG0848	biopolymer transport protein
BTL45_RS15645	COG2835	tetraacyldisaccharide 4'-kinase activity
BTL45_RS15655	COG0563	adenylate kinase activity
BTL45_RS15665	COG0728	peptidoglycan biosynthetic process
BTL45_RS15675	COG0268	Binds directly to 16S ribosomal RNA
BTL45_RS15695	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL45_RS15700	COG2186	Transcriptional regulator
BTL45_RS15720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTL45_RS15730	COG0583	DNA-binding transcription factor activity
BTL45_RS15740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL45_RS15745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTL45_RS15750	COG0137	argininosuccinate synthase activity
BTL45_RS15755	COG3158	transport of potassium into the cell
BTL45_RS15760	COG0642	Histidine kinase
BTL45_RS15790	COG0776	regulation of translation
BTL45_RS15795	COG3128	pkhd-type hydroxylase
BTL45_RS15805	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTL45_RS15810	COG0557	exoribonuclease II activity
BTL45_RS15835	COG0679	Auxin Efflux Carrier
BTL45_RS15840	COG2391	methyltransferase activity
BTL45_RS15845	COG0069	glutamate synthase activity
BTL45_RS15850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTL45_RS15860	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BTL45_RS15865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BTL45_RS15920	COG3706	GGDEF domain
BTL45_RS15950	COG3909	cytochrome
BTL45_RS15955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTL45_RS15960	COG0625	glutathione transferase activity
BTL45_RS15965	COG0730	response to heat
BTL45_RS15970	COG0482	sulfurtransferase activity
BTL45_RS15975	COG0583	DNA-binding transcription factor activity
BTL45_RS16015	COG2819	hydrolase of the alpha beta superfamily
BTL45_RS16020	COG0247	lactate metabolic process
BTL45_RS16025	COG0277	FAD linked oxidase domain protein
BTL45_RS16030	COG0277	FAD linked oxidase domain protein
BTL45_RS16035	COG0277	FAD linked oxidase domain protein
BTL45_RS16040	COG3064	Membrane
BTL45_RS16040	COG3064	Membrane
BTL45_RS16040	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL45_RS16040	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BTL45_RS16040	COG3210	domain, Protein
BTL45_RS16040	COG3210	domain, Protein
BTL45_RS16045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTL45_RS16050	COG0312	modulator of DNA gyrase
BTL45_RS16070	COG0308	aminopeptidase N
BTL45_RS16075	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BTL45_RS16095	COG0436	Aminotransferase
BTL45_RS16100	COG3737	Protein of unknown function (DUF498/DUF598)
BTL45_RS16105	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTL45_RS16110	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTL45_RS16115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTL45_RS16125	COG0305	Participates in initiation and elongation during chromosome replication
BTL45_RS16140	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTL45_RS16145	COG2965	DNA replication, synthesis of RNA primer
BTL45_RS16150	COG0360	Binds together with S18 to 16S ribosomal RNA
BTL45_RS16155	COG1469	GTP cyclohydrolase I activity
BTL45_RS16165	COG0142	geranyltranstransferase activity
BTL45_RS16170	COG1722	exodeoxyribonuclease VII activity
BTL45_RS16180	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS16200	COG1840	ABC-type Fe3 transport system, periplasmic component
BTL45_RS16205	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTL45_RS16210	COG1178	ABC-type Fe3 transport system permease component
BTL45_RS16215	COG3842	ATPase activity
BTL45_RS16220	COG0583	DNA-binding transcription factor activity
BTL45_RS16240	COG0501	Belongs to the peptidase M48B family
BTL45_RS16250	COG0697	spore germination
BTL45_RS16260	COG1846	Transcriptional regulator
BTL45_RS16270	COG1566	PFAM secretion protein HlyD family protein
BTL45_RS16275	COG2814	Major facilitator Superfamily
BTL45_RS16280	COG0473	3-isopropylmalate dehydrogenase activity
BTL45_RS16290	COG0747	negative chemotaxis
BTL45_RS16300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS16310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTL45_RS16335	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS16345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL45_RS16350	COG1115	amino acid carrier protein
BTL45_RS16355	COG0433	COG0433 Predicted ATPase
BTL45_RS16365	COG0151	Belongs to the GarS family
BTL45_RS16375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BTL45_RS16380	COG0799	negative regulation of ribosome biogenesis
BTL45_RS16385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BTL45_RS16390	COG0424	maF-like protein
BTL45_RS16395	COG3468	outer membrane autotransporter barrel domain protein
BTL45_RS16425	COG1530	ribonuclease E activity
BTL45_RS16445	COG1132	(ABC) transporter
BTL45_RS16450	COG0859	PFAM glycosyl transferase family 9
BTL45_RS16475	COG2194	sulfuric ester hydrolase activity
BTL45_RS16480	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS16485	COG0463	Glycosyl transferase, family 2
BTL45_RS16490	COG0726	polysaccharide deacetylase
BTL45_RS16495	COG0438	transferase activity, transferring glycosyl groups
BTL45_RS16510	COG1643	Atp-dependent helicase
BTL45_RS16515	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTL45_RS16515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL45_RS16520	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BTL45_RS16530	COG0704	Plays a role in the regulation of phosphate uptake
BTL45_RS16540	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS16565	COG1177	transmembrane transport
BTL45_RS16570	COG1176	ABC-type spermidine putrescine transport system, permease component I
BTL45_RS16575	COG3842	ATPase activity
BTL45_RS16580	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTL45_RS16595	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BTL45_RS16600	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS16610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS16610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS16615	COG3539	Fimbrial protein
BTL45_RS16620	COG3539	Fimbrial protein
BTL45_RS16625	COG3539	Fimbrial protein
BTL45_RS16630	COG3539	Fimbrial protein
BTL45_RS16640	COG2050	protein possibly involved in aromatic compounds catabolism
BTL45_RS16645	COG1024	Enoyl-CoA hydratase
BTL45_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS16655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTL45_RS16660	COG2151	metal-sulfur cluster biosynthetic enzyme
BTL45_RS16665	COG3396	Phenylacetate-CoA oxygenase
BTL45_RS16670	COG3460	Phenylacetate-CoA oxygenase
BTL45_RS16675	COG3396	Phenylacetate-CoA oxygenase
BTL45_RS16680	COG3327	negative regulation of DNA-templated transcription, initiation
BTL45_RS16690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BTL45_RS16695	COG0501	Belongs to the peptidase M48B family
BTL45_RS16700	COG1162	GTPase activity
BTL45_RS16705	COG0667	Aldo Keto reductase
BTL45_RS16715	COG0335	large ribosomal subunit rRNA binding
BTL45_RS16745	COG0175	sulfate reduction
BTL45_RS16755	COG4208	sulfate ABC transporter
BTL45_RS16760	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BTL45_RS16770	COG0450	alkyl hydroperoxide reductase
BTL45_RS16775	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS16790	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTL45_RS16795	COG2951	lytic endotransglycosylase activity
BTL45_RS16805	COG1555	photosystem II stabilization
BTL45_RS16805	COG1596	polysaccharide export
BTL45_RS16810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL45_RS16815	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BTL45_RS16820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BTL45_RS16840	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BTL45_RS16845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTL45_RS16850	COG0287	Prephenate dehydrogenase
BTL45_RS16860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BTL45_RS16875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTL45_RS16885	COG2814	Major facilitator Superfamily
BTL45_RS16905	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTL45_RS16910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTL45_RS16920	COG0583	DNA-binding transcription factor activity
BTL45_RS16930	COG0583	DNA-binding transcription factor activity
BTL45_RS16970	COG0583	DNA-binding transcription factor activity
BTL45_RS16985	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTL45_RS17010	COG1053	succinate dehydrogenase
BTL45_RS17015	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS17020	COG2079	MmgE PrpD family protein
BTL45_RS17030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS17045	COG0583	DNA-binding transcription factor activity
BTL45_RS17055	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BTL45_RS17055	COG0028	Belongs to the TPP enzyme family
BTL45_RS17060	COG0436	Aminotransferase
BTL45_RS17080	COG0778	Nitroreductase
BTL45_RS17085	COG2814	Major facilitator Superfamily
BTL45_RS17090	COG3706	GGDEF domain
BTL45_RS17095	COG0589	response to stress
BTL45_RS17105	COG2951	lytic endotransglycosylase activity
BTL45_RS17110	COG2833	Protein of unknown function (DUF455)
BTL45_RS17125	COG1132	(ABC) transporter
BTL45_RS17130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTL45_RS17130	COG0189	ligase activity
BTL45_RS17135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTL45_RS17135	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTL45_RS17140	COG3237	CsbD-like
BTL45_RS17150	COG2823	Periplasmic or secreted lipoprotein
BTL45_RS17165	COG0672	)-iron permease
BTL45_RS17180	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BTL45_RS17185	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS17190	COG3243	poly(R)-hydroxyalkanoic acid synthase
BTL45_RS17200	COG0564	pseudouridine synthase activity
BTL45_RS17210	COG1199	ATP-dependent helicase activity
BTL45_RS17215	COG2183	response to ionizing radiation
BTL45_RS17240	COG4774	siderophore transport
BTL45_RS17245	COG3712	iron ion homeostasis
BTL45_RS17250	COG1595	DNA-templated transcription, initiation
BTL45_RS17255	COG2175	clavaminate synthase activity
BTL45_RS17265	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS17270	COG0583	DNA-binding transcription factor activity
BTL45_RS17275	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS17280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BTL45_RS17285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL45_RS17290	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL45_RS17295	COG0567	Dehydrogenase, E1 component
BTL45_RS17300	COG1297	OPT oligopeptide transporter protein
BTL45_RS17305	COG1522	sequence-specific DNA binding
BTL45_RS17315	COG0281	malic enzyme
BTL45_RS17315	COG0280	phosphate acetyltransferase
BTL45_RS17320	COG3539	Fimbrial protein
BTL45_RS17335	COG0372	Belongs to the citrate synthase family
BTL45_RS17340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BTL45_RS17345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTL45_RS17350	COG1053	succinate dehydrogenase
BTL45_RS17355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BTL45_RS17360	COG2009	succinate dehydrogenase
BTL45_RS17365	COG2188	Transcriptional regulator
BTL45_RS17370	COG0039	L-malate dehydrogenase activity
BTL45_RS17390	COG2828	Protein conserved in bacteria
BTL45_RS17400	COG1981	membrane
BTL45_RS17425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL45_RS17435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BTL45_RS17465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BTL45_RS17470	COG0148	phosphopyruvate hydratase activity
BTL45_RS17480	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BTL45_RS17485	COG0504	CTP synthase activity
BTL45_RS17505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS17515	COG0747	negative chemotaxis
BTL45_RS17520	COG4172	Belongs to the ABC transporter superfamily
BTL45_RS17525	COG1446	asparaginase
BTL45_RS17555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTL45_RS17570	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BTL45_RS17575	COG0697	spore germination
BTL45_RS17580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL45_RS17590	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BTL45_RS17595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTL45_RS17600	COG0791	NLP P60 protein
BTL45_RS17610	COG0583	DNA-binding transcription factor activity
BTL45_RS17625	COG0583	DNA-binding transcription factor activity
BTL45_RS17635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTL45_RS17650	COG0670	Belongs to the BI1 family
BTL45_RS17665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTL45_RS17675	COG1381	Involved in DNA repair and RecF pathway recombination
BTL45_RS17680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTL45_RS17685	COG0571	ribonuclease III activity
BTL45_RS17690	COG0681	Belongs to the peptidase S26 family
BTL45_RS17700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTL45_RS17725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTL45_RS17730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTL45_RS17745	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL45_RS17750	COG0416	fatty acid biosynthetic process
BTL45_RS17755	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTL45_RS17760	COG1399	metal-binding, possibly nucleic acid-binding protein
BTL45_RS17765	COG0424	maF-like protein
BTL45_RS17775	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTL45_RS17780	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BTL45_RS17785	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BTL45_RS17790	COG0546	phosphoglycolate phosphatase activity
BTL45_RS17800	COG1530	ribonuclease E activity
BTL45_RS17810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTL45_RS17815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTL45_RS17820	COG0159	tryptophan synthase activity
BTL45_RS17825	COG0133	tryptophan synthase activity
BTL45_RS17835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTL45_RS17840	COG3228	Belongs to the MtfA family
BTL45_RS17850	COG0251	oxidation-reduction process
BTL45_RS17855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTL45_RS17860	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BTL45_RS17875	COG2878	Part of a membrane complex involved in electron transport
BTL45_RS17880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTL45_RS17915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL45_RS17940	COG1268	BioY protein
BTL45_RS17945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BTL45_RS17950	COG1122	ATPase activity
BTL45_RS17955	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL45_RS17965	COG0271	Belongs to the BolA IbaG family
BTL45_RS17970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL45_RS17975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTL45_RS17985	COG1196	nuclear chromosome segregation
BTL45_RS17990	COG0477	Major facilitator Superfamily
BTL45_RS17995	COG1573	uracil-dna glycosylase
BTL45_RS18000	COG1214	PFAM Peptidase M22, glycoprotease
BTL45_RS18015	COG0450	alkyl hydroperoxide reductase
BTL45_RS18020	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS18030	COG2223	nitrite transmembrane transporter activity
BTL45_RS18035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BTL45_RS18045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTL45_RS18050	COG0560	Phosphoserine phosphatase
BTL45_RS18055	COG0583	DNA-binding transcription factor activity
BTL45_RS18060	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS18065	COG0028	Belongs to the TPP enzyme family
BTL45_RS18080	COG4774	siderophore transport
BTL45_RS18085	COG4774	siderophore transport
BTL45_RS18095	COG1007	ATP synthesis coupled electron transport
BTL45_RS18110	COG0713	ATP synthesis coupled electron transport
BTL45_RS18120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL45_RS18125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTL45_RS18130	COG1034	ATP synthesis coupled electron transport
BTL45_RS18140	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTL45_RS18150	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL45_RS18155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL45_RS18160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTL45_RS18165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL45_RS18185	COG0671	phosphoesterase, PA-phosphatase related
BTL45_RS18195	COG1597	lipid kinase activity
BTL45_RS18200	COG0583	DNA-binding transcription factor activity
BTL45_RS18205	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTL45_RS18210	COG1733	regulation of RNA biosynthetic process
BTL45_RS18215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS18220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL45_RS18235	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BTL45_RS18255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS18275	COG3608	succinylglutamate desuccinylase aspartoacylase
BTL45_RS18280	COG0626	cystathionine gamma-synthase activity
BTL45_RS18285	COG0583	DNA-binding transcription factor activity
BTL45_RS18295	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS18300	COG0165	Argininosuccinate lyase
BTL45_RS18315	COG3799	methylaspartate ammonia-lyase activity
BTL45_RS18325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTL45_RS18335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTL45_RS18340	COG0149	triose-phosphate isomerase activity
BTL45_RS18360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL45_RS18370	COG1185	polyribonucleotide nucleotidyltransferase activity
BTL45_RS18375	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BTL45_RS18390	COG1183	phosphatidylcholine synthase activity
BTL45_RS18400	COG0440	acetolactate synthase activity
BTL45_RS18405	COG0028	Belongs to the TPP enzyme family
BTL45_RS18410	COG1289	transmembrane transporter activity
BTL45_RS18420	COG3022	response to hydroperoxide
BTL45_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS18440	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BTL45_RS18485	COG1024	Enoyl-CoA hydratase
BTL45_RS18490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS18515	COG3706	GGDEF domain
BTL45_RS18545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTL45_RS18550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTL45_RS18555	COG1674	ftsk spoiiie
BTL45_RS18560	COG0492	ferredoxin-NADP+ reductase activity
BTL45_RS18565	COG1193	negative regulation of DNA recombination
BTL45_RS18575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTL45_RS18590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BTL45_RS18595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BTL45_RS18600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BTL45_RS18605	COG2205	protein histidine kinase activity
BTL45_RS18610	COG0745	RESPONSE REGULATOR receiver
BTL45_RS18645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTL45_RS18665	COG0612	Peptidase, M16
BTL45_RS18670	COG0484	heat shock protein binding
BTL45_RS18675	COG0443	Heat shock 70 kDa protein
BTL45_RS18685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTL45_RS18695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BTL45_RS18700	COG1420	regulation of RNA biosynthetic process
BTL45_RS18710	COG0497	DNA recombination
BTL45_RS18715	COG0735	belongs to the Fur family
BTL45_RS18720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTL45_RS18730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BTL45_RS18765	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTL45_RS18765	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTL45_RS18770	COG4311	Sarcosine oxidase, delta subunit
BTL45_RS18775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS18785	COG0583	DNA-binding transcription factor activity
BTL45_RS18795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTL45_RS18805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS18810	COG2030	dehydratase
BTL45_RS18820	COG1024	Enoyl-CoA hydratase
BTL45_RS18835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTL45_RS18845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTL45_RS18845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTL45_RS18860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BTL45_RS18865	COG0730	response to heat
BTL45_RS18875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS18885	COG0405	Gamma-glutamyltransferase
BTL45_RS18900	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS18930	COG0583	DNA-binding transcription factor activity
BTL45_RS18940	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BTL45_RS18945	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BTL45_RS18950	COG0167	dihydroorotate dehydrogenase activity
BTL45_RS18965	COG1414	Transcriptional regulator
BTL45_RS18970	COG1546	Belongs to the CinA family
BTL45_RS18970	COG1058	Belongs to the CinA family
BTL45_RS18985	COG0513	Belongs to the DEAD box helicase family
BTL45_RS19015	COG0429	hydrolase of the alpha beta-hydrolase fold
BTL45_RS19020	COG4783	chaperone-mediated protein folding
BTL45_RS19035	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL45_RS19050	COG0006	proline dipeptidase activity
BTL45_RS19060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL45_RS19105	COG0514	ATP-dependent DNA helicase (RecQ)
BTL45_RS19130	COG1271	oxidase subunit
BTL45_RS19135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL45_RS19140	COG0850	regulation of cytokinetic process
BTL45_RS19145	COG2894	cell division
BTL45_RS19150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTL45_RS19165	COG0488	(ABC) transporter
BTL45_RS19190	COG4608	Belongs to the ABC transporter superfamily
BTL45_RS19195	COG0444	Belongs to the ABC transporter superfamily
BTL45_RS19200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS19205	COG0601	transmembrane transport
BTL45_RS19215	COG1215	transferase activity, transferring glycosyl groups
BTL45_RS19220	COG0583	DNA-binding transcription factor activity
BTL45_RS19230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTL45_RS19240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTL45_RS19255	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS19260	COG2188	Transcriptional regulator
BTL45_RS19265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTL45_RS19270	COG2814	Major facilitator Superfamily
BTL45_RS19280	COG0259	pyridoxamine-phosphate oxidase activity
BTL45_RS19285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTL45_RS19300	COG0583	DNA-binding transcription factor activity
BTL45_RS19305	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS19315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS19320	COG0405	Gamma-glutamyltransferase
BTL45_RS19330	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS19345	COG0802	atpase or kinase
BTL45_RS19350	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTL45_RS19355	COG0586	Pfam SNARE associated Golgi protein
BTL45_RS19360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTL45_RS19365	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTL45_RS19370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTL45_RS19385	COG0617	tRNA 3'-terminal CCA addition
BTL45_RS19410	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS19415	COG2188	Transcriptional regulator
BTL45_RS19425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTL45_RS19430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTL45_RS19435	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS19445	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS19450	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS19455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTL45_RS19460	COG2301	Belongs to the HpcH HpaI aldolase family
BTL45_RS19465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS19470	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BTL45_RS19480	COG1024	Enoyl-CoA hydratase
BTL45_RS19490	COG2188	Transcriptional regulator
BTL45_RS19495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTL45_RS19500	COG0066	3-isopropylmalate dehydratase activity
BTL45_RS19515	COG0752	glycyl-tRNA synthetase alpha subunit
BTL45_RS19520	COG0751	glycine-tRNA ligase activity
BTL45_RS19525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTL45_RS19530	COG0204	Acyl-transferase
BTL45_RS19545	COG0242	peptide deformylase activity
BTL45_RS19550	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS19555	COG0700	Nucleoside recognition
BTL45_RS19560	COG0469	pyruvate kinase activity
BTL45_RS19565	COG1929	Belongs to the glycerate kinase type-1 family
BTL45_RS19570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTL45_RS19575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTL45_RS19590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BTL45_RS19600	COG2154	pterin-4-alpha-carbinolamine dehydratase
BTL45_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS19630	COG0028	Belongs to the TPP enzyme family
BTL45_RS19635	COG3386	PFAM SMP-30 Gluconolaconase
BTL45_RS19645	COG1802	Transcriptional regulator
BTL45_RS19655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTL45_RS19660	COG0154	amidase activity
BTL45_RS19670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS19675	COG0601	transmembrane transport
BTL45_RS19680	COG0747	negative chemotaxis
BTL45_RS19700	COG0019	diaminopimelate decarboxylase activity
BTL45_RS19715	COG3712	iron ion homeostasis
BTL45_RS19720	COG4774	siderophore transport
BTL45_RS19725	COG2353	YceI-like domain
BTL45_RS19750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTL45_RS19765	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS19780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTL45_RS19825	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS19830	COG1309	transcriptional regulator
BTL45_RS19835	COG2982	Protein involved in outer membrane biogenesis
BTL45_RS19840	COG2818	Glycosylase
BTL45_RS19865	COG2011	ABC-type metal ion transport system permease component
BTL45_RS19870	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTL45_RS19875	COG1501	Belongs to the glycosyl hydrolase 31 family
BTL45_RS19880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS19880	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BTL45_RS19890	COG0318	PFAM AMP-dependent synthetase and ligase
BTL45_RS19895	COG1473	amidohydrolase
BTL45_RS19905	COG2855	membrane
BTL45_RS19915	COG2239	Acts as a magnesium transporter
BTL45_RS19930	COG1522	sequence-specific DNA binding
BTL45_RS19935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS19940	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS19960	COG0653	protein targeting
BTL45_RS19965	COG0739	heme binding
BTL45_RS19975	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BTL45_RS19980	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTL45_RS19990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTL45_RS19995	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTL45_RS20005	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTL45_RS20015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTL45_RS20020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTL45_RS20025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTL45_RS20035	COG3116	cell division
BTL45_RS20040	COG0275	rRNA processing
BTL45_RS20045	COG2001	Belongs to the MraZ family
BTL45_RS20055	COG0488	(ABC) transporter
BTL45_RS20060	COG0418	dihydroorotase activity
BTL45_RS20065	COG1473	amidohydrolase
BTL45_RS20115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTL45_RS20120	COG4654	Cytochrome c, class I
BTL45_RS20125	COG0129	dihydroxy-acid dehydratase activity
BTL45_RS20130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTL45_RS20170	COG2084	Dehydrogenase
BTL45_RS20210	COG0442	prolyl-tRNA aminoacylation
BTL45_RS20215	COG0824	Thioesterase
BTL45_RS20220	COG0811	peptide transport
BTL45_RS20225	COG0848	biopolymer transport protein
BTL45_RS20235	COG0823	Involved in the tonB-independent uptake of proteins
BTL45_RS20250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL45_RS20255	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BTL45_RS20260	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS20275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTL45_RS20300	COG0183	Belongs to the thiolase family
BTL45_RS20310	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS20315	COG0583	DNA-binding transcription factor activity
BTL45_RS20320	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS20325	COG1024	Enoyl-CoA hydratase
BTL45_RS20330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS20335	COG1253	flavin adenine dinucleotide binding
BTL45_RS20340	COG1285	pathogenesis
BTL45_RS20345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTL45_RS20360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTL45_RS20365	COG0697	spore germination
BTL45_RS20395	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BTL45_RS20400	COG0463	Glycosyl transferase, family 2
BTL45_RS20410	COG0786	glutamate:sodium symporter activity
BTL45_RS20420	COG2031	fatty acid transporter
BTL45_RS20435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTL45_RS20440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTL45_RS20445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTL45_RS20450	COG0328	RNA-DNA hybrid ribonuclease activity
BTL45_RS20455	COG2226	methyltransferase
BTL45_RS20460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTL45_RS20465	COG0741	lytic transglycosylase activity
BTL45_RS20465	COG1388	LysM domain
BTL45_RS20480	COG2979	Protein of unknown function (DUF533)
BTL45_RS20550	COG0154	amidase activity
BTL45_RS20560	COG2816	NAD+ diphosphatase activity
BTL45_RS20565	COG1309	transcriptional regulator
BTL45_RS20570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS20585	COG1024	Enoyl-CoA hydratase
BTL45_RS20600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS20615	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS20630	COG3119	arylsulfatase activity
BTL45_RS20655	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BTL45_RS20660	COG0830	nickel cation binding
BTL45_RS20670	COG0804	urea catabolic process
BTL45_RS20675	COG0832	Belongs to the urease beta subunit family
BTL45_RS20685	COG0831	urea catabolic process
BTL45_RS20690	COG0829	nickel cation binding
BTL45_RS20700	COG0633	Ferredoxin
BTL45_RS20715	COG2188	Transcriptional regulator
BTL45_RS20720	COG3799	methylaspartate ammonia-lyase activity
BTL45_RS20740	COG2719	SpoVR family
BTL45_RS20745	COG2718	Belongs to the UPF0229 family
BTL45_RS20750	COG2766	serine protein kinase
BTL45_RS20755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL45_RS20755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTL45_RS20765	COG4977	sequence-specific DNA binding
BTL45_RS20770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTL45_RS20775	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BTL45_RS20785	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTL45_RS20800	COG0316	Belongs to the HesB IscA family
BTL45_RS20810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTL45_RS20815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTL45_RS20820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BTL45_RS20825	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTL45_RS20830	COG0312	modulator of DNA gyrase
BTL45_RS20850	COG1116	anion transmembrane transporter activity
BTL45_RS20855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS20860	COG1335	isochorismatase
BTL45_RS20865	COG0346	lactoylglutathione lyase activity
BTL45_RS20870	COG0513	Belongs to the DEAD box helicase family
BTL45_RS20875	COG3069	C4-dicarboxylate transmembrane transporter activity
BTL45_RS20880	COG1802	Transcriptional regulator
BTL45_RS20885	COG0045	succinate-CoA ligase (ADP-forming) activity
BTL45_RS20885	COG1042	CoA-binding domain protein
BTL45_RS20885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTL45_RS20890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL45_RS20905	COG1522	sequence-specific DNA binding
BTL45_RS20935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTL45_RS20940	COG1696	Membrane protein involved in D-alanine export
BTL45_RS20965	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTL45_RS20975	COG2264	protein methyltransferase activity
BTL45_RS20980	COG0439	Biotin carboxylase
BTL45_RS20985	COG0511	ligase activity, forming carbon-carbon bonds
BTL45_RS20990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTL45_RS20995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTL45_RS21000	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTL45_RS21005	COG3150	esterase
BTL45_RS21010	COG0557	exoribonuclease II activity
BTL45_RS21020	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTL45_RS21025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTL45_RS21050	COG0540	Belongs to the ATCase OTCase family
BTL45_RS21060	COG1678	Uncharacterized ACR, COG1678
BTL45_RS21075	COG0352	thiamine-phosphate diphosphorylase activity
BTL45_RS21080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BTL45_RS21105	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS21110	COG1024	Enoyl-CoA hydratase
BTL45_RS21115	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS21175	COG0494	nUDIX hydrolase
BTL45_RS21200	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BTL45_RS21210	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BTL45_RS21225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTL45_RS21230	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BTL45_RS21240	COG0477	Major facilitator Superfamily
BTL45_RS21260	COG1126	abc transporter atp-binding protein
BTL45_RS21265	COG0765	amino acid transport
BTL45_RS21270	COG4597	amino acid ABC transporter
BTL45_RS21275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS21280	COG2884	Cell division ATP-binding protein ftsE
BTL45_RS21285	COG2177	Part of the ABC transporter FtsEX involved in
BTL45_RS21290	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BTL45_RS21300	COG1194	a g-specific adenine glycosylase
BTL45_RS21310	COG2226	methyltransferase
BTL45_RS21320	COG4206	TonB-dependent receptor
BTL45_RS21325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTL45_RS21330	COG2022	thiamine diphosphate biosynthetic process
BTL45_RS21335	COG0351	phosphomethylpyrimidine kinase
BTL45_RS21340	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTL45_RS21350	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTL45_RS21360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTL45_RS21375	COG2226	methyltransferase
BTL45_RS21380	COG0745	RESPONSE REGULATOR receiver
BTL45_RS21385	COG5002	protein histidine kinase activity
BTL45_RS21395	COG5002	protein histidine kinase activity
BTL45_RS21405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL45_RS21410	COG0583	DNA-binding transcription factor activity
BTL45_RS21420	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTL45_RS21425	COG1984	allophanate hydrolase subunit 2
BTL45_RS21440	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS21450	COG1024	Enoyl-CoA hydratase
BTL45_RS21465	COG1802	Transcriptional regulator
BTL45_RS21475	COG1238	metal cluster binding
BTL45_RS21480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTL45_RS21485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL45_RS21505	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTL45_RS21510	COG4988	ABC transporter
BTL45_RS21520	COG1294	oxidase, subunit
BTL45_RS21540	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BTL45_RS21550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BTL45_RS21565	COG1137	ATPase activity
BTL45_RS21570	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTL45_RS21585	COG2010	Cytochrome c
BTL45_RS21585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BTL45_RS21595	COG1660	Displays ATPase and GTPase activities
BTL45_RS21605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTL45_RS21620	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTL45_RS21625	COG2823	Periplasmic or secreted lipoprotein
BTL45_RS21640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTL45_RS21650	COG1309	transcriptional regulator
BTL45_RS21655	COG0471	metal ion transport
BTL45_RS21660	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL45_RS21665	COG0772	Belongs to the SEDS family
BTL45_RS21670	COG0768	penicillin binding
BTL45_RS21680	COG1792	Involved in formation and maintenance of cell shape
BTL45_RS21685	COG1077	Cell shape determining protein MreB Mrl
BTL45_RS21690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL45_RS21700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTL45_RS21705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTL45_RS21710	COG0708	Exodeoxyribonuclease III
BTL45_RS21715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTL45_RS21720	COG2860	membrane
BTL45_RS21730	COG0583	DNA-binding transcription factor activity
BTL45_RS21735	COG0473	3-isopropylmalate dehydrogenase activity
BTL45_RS21740	COG3391	amine dehydrogenase activity
BTL45_RS21760	COG0583	DNA-binding transcription factor activity
BTL45_RS21765	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTL45_RS21770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTL45_RS21775	COG0765	amino acid transport
BTL45_RS21780	COG0765	amino acid transport
BTL45_RS21785	COG1126	abc transporter atp-binding protein
BTL45_RS21790	COG1794	racemase activity, acting on amino acids and derivatives
BTL45_RS21795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL45_RS21800	COG2223	nitrite transmembrane transporter activity
BTL45_RS21805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BTL45_RS21805	COG2813	Specifically methylates the guanine in position
BTL45_RS21815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BTL45_RS21840	COG2918	glutathione biosynthetic process
BTL45_RS21860	COG0583	DNA-binding transcription factor activity
BTL45_RS21865	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTL45_RS21870	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTL45_RS21905	COG0154	amidase activity
BTL45_RS21915	COG1414	Transcriptional regulator
BTL45_RS21925	COG1024	Enoyl-CoA hydratase
BTL45_RS21925	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS21935	COG2132	Multicopper oxidase
BTL45_RS21955	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTL45_RS21980	COG1024	Enoyl-CoA hydratase
BTL45_RS21985	COG1024	Enoyl-CoA hydratase
BTL45_RS21990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BTL45_RS22000	COG0747	negative chemotaxis
BTL45_RS22010	COG0601	transmembrane transport
BTL45_RS22015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS22020	COG0444	Belongs to the ABC transporter superfamily
BTL45_RS22025	COG4608	Belongs to the ABC transporter superfamily
BTL45_RS22035	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTL45_RS22040	COG0210	DNA helicase
BTL45_RS22045	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTL45_RS22050	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BTL45_RS22060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTL45_RS22070	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTL45_RS22080	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTL45_RS22095	COG0356	it plays a direct role in the translocation of protons across the membrane
BTL45_RS22110	COG1024	Enoyl-CoA hydratase
BTL45_RS22130	COG0037	tRNA processing
BTL45_RS22135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTL45_RS22145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTL45_RS22150	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BTL45_RS22155	COG2967	ApaG domain
BTL45_RS22160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTL45_RS22165	COG0546	phosphoglycolate phosphatase activity
BTL45_RS22175	COG0512	Glutamine amidotransferase of anthranilate synthase
BTL45_RS22180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTL45_RS22190	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS22210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTL45_RS22220	COG1607	acyl-coa hydrolase
BTL45_RS22270	COG3069	C4-dicarboxylate transmembrane transporter activity
BTL45_RS22280	COG1802	Transcriptional regulator
BTL45_RS22310	COG1595	DNA-templated transcription, initiation
BTL45_RS22315	COG3712	iron ion homeostasis
BTL45_RS22325	COG3720	iron ion transport
BTL45_RS22330	COG4558	Periplasmic binding protein
BTL45_RS22335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTL45_RS22340	COG1120	ATPase activity
BTL45_RS22345	COG1683	Conserved Protein
BTL45_RS22375	COG3064	Membrane
BTL45_RS22380	COG0583	DNA-binding transcription factor activity
BTL45_RS22390	COG1234	tRNA 3'-trailer cleavage
BTL45_RS22415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BTL45_RS22420	COG1802	Transcriptional regulator
BTL45_RS22430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL45_RS22435	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS22470	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22475	COG0583	DNA-binding transcription factor activity
BTL45_RS22485	COG1053	succinate dehydrogenase
BTL45_RS22490	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTL45_RS22515	COG0411	ABC transporter
BTL45_RS22520	COG0559	Belongs to the binding-protein-dependent transport system permease family
BTL45_RS22525	COG0683	leucine binding
BTL45_RS22545	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTL45_RS22550	COG1024	Enoyl-CoA hydratase
BTL45_RS22555	COG0022	dehydrogenase e1 component
BTL45_RS22560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTL45_RS22585	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS22590	COG1024	Enoyl-CoA hydratase
BTL45_RS22595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTL45_RS22615	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS22620	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS22635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTL45_RS22650	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTL45_RS22655	COG1984	allophanate hydrolase subunit 2
BTL45_RS22660	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BTL45_RS22665	COG0747	negative chemotaxis
BTL45_RS22670	COG0601	transmembrane transport
BTL45_RS22675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS22705	COG0511	ligase activity, forming carbon-carbon bonds
BTL45_RS22710	COG0439	Biotin carboxylase
BTL45_RS22725	COG0709	Synthesizes selenophosphate from selenide and ATP
BTL45_RS22730	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BTL45_RS22765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS22775	COG0604	alcohol dehydrogenase
BTL45_RS22785	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS22795	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS22805	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22810	COG1024	Enoyl-CoA hydratase
BTL45_RS22815	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTL45_RS22815	COG1902	pentaerythritol trinitrate reductase activity
BTL45_RS22820	COG1024	Enoyl-CoA hydratase
BTL45_RS22825	COG1846	Transcriptional regulator
BTL45_RS22845	COG4771	TonB-dependent receptor
BTL45_RS22860	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS22865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS22870	COG0183	Belongs to the thiolase family
BTL45_RS22875	COG2030	dehydratase
BTL45_RS22880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS22890	COG0346	lactoylglutathione lyase activity
BTL45_RS22920	COG3842	ATPase activity
BTL45_RS22930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTL45_RS22940	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BTL45_RS22945	COG0583	DNA-binding transcription factor activity
BTL45_RS22960	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS22970	COG0277	FAD linked oxidase domain protein
BTL45_RS22975	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS22980	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS22990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTL45_RS23005	COG2072	flavoprotein involved in K transport
BTL45_RS23010	COG0604	alcohol dehydrogenase
BTL45_RS23025	COG1024	Enoyl-CoA hydratase
BTL45_RS23035	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS23050	COG1522	sequence-specific DNA binding
BTL45_RS23060	COG2207	Transcriptional regulator
BTL45_RS23060	COG3708	Transcriptional regulator
BTL45_RS23075	COG2814	Major facilitator Superfamily
BTL45_RS23080	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTL45_RS23100	COG1999	signal sequence binding
BTL45_RS23145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTL45_RS23170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BTL45_RS23175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTL45_RS23185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BTL45_RS23190	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BTL45_RS23200	COG0070	glutamate synthase
BTL45_RS23200	COG0069	glutamate synthase activity
BTL45_RS23200	COG0067	glutamate synthase
BTL45_RS23210	COG3047	cAMP biosynthetic process
BTL45_RS23220	COG1127	ABC transporter
BTL45_RS23225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTL45_RS23230	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTL45_RS23235	COG2853	Lipoprotein
BTL45_RS23245	COG1131	(ABC) transporter
BTL45_RS23250	COG0842	Transport permease protein
BTL45_RS23260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTL45_RS23270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTL45_RS23275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTL45_RS23280	COG0131	Imidazoleglycerol-phosphate dehydratase
BTL45_RS23290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BTL45_RS23295	COG0107	imidazoleglycerol-phosphate synthase activity
BTL45_RS23305	COG0140	phosphoribosyl-ATP diphosphatase activity
BTL45_RS23310	COG0537	adenosine 5'-monophosphoramidase activity
BTL45_RS23315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL45_RS23320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTL45_RS23325	COG0805	protein transport
BTL45_RS23340	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTL45_RS23345	COG1970	mechanosensitive ion channel activity
BTL45_RS23350	COG0723	plastoquinol--plastocyanin reductase activity
BTL45_RS23355	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTL45_RS23360	COG2857	Cytochrome c1
BTL45_RS23365	COG0625	glutathione transferase activity
BTL45_RS23370	COG2969	positive regulation of protein catabolic process
BTL45_RS23400	COG0583	DNA-binding transcription factor activity
BTL45_RS23405	COG0492	ferredoxin-NADP+ reductase activity
BTL45_RS23425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS23440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BTL45_RS23460	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS23480	COG0697	spore germination
BTL45_RS23500	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTL45_RS23505	COG0747	negative chemotaxis
BTL45_RS23510	COG0601	transmembrane transport
BTL45_RS23515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTL45_RS23525	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BTL45_RS23535	COG0513	Belongs to the DEAD box helicase family
BTL45_RS23540	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS23545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BTL45_RS23565	COG0583	DNA-binding transcription factor activity
BTL45_RS23575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BTL45_RS23585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTL45_RS23590	COG0154	amidase activity
BTL45_RS23595	COG1609	Transcriptional regulator
BTL45_RS23615	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BTL45_RS23620	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BTL45_RS23625	COG3842	ATPase activity
BTL45_RS23630	COG1653	transport
BTL45_RS23635	COG1175	transmembrane transport
BTL45_RS23640	COG0395	ABC-type sugar transport system, permease component
BTL45_RS23655	COG0018	arginyl-trna synthetase
BTL45_RS23675	COG1280	lysine exporter protein (LysE YggA)
BTL45_RS23690	COG1960	acyl-CoA dehydrogenase activity
BTL45_RS23695	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BTL45_RS23700	COG0183	Belongs to the thiolase family
BTL45_RS23705	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BTL45_RS23720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTL45_RS23725	COG3181	Tripartite tricarboxylate transporter family receptor
BTL45_RS23735	COG2358	TRAP transporter, solute receptor (TAXI family
BTL45_RS23745	COG1629	transport
BTL45_RS23750	COG2922	Belongs to the Smg family
BTL45_RS23755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTL45_RS23775	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL45_RS23780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS23785	COG1028	Short-chain dehydrogenase reductase Sdr
BTL45_RS23790	COG1012	belongs to the aldehyde dehydrogenase family
BTL45_RS23800	COG0028	Belongs to the TPP enzyme family
BTL45_RS23805	COG1522	sequence-specific DNA binding
BTL45_RS23810	COG3781	membrane
BTL45_RS23840	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTL45_RS23865	COG1304	FMN binding
BTL45_RS23880	COG0154	amidase activity
BTL45_RS23885	COG1414	Transcriptional regulator
BTL45_RS23900	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTL45_RS23905	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTL45_RS23910	COG0594	ribonuclease P activity
BTL45_RS23915	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTL45_RS23920	COG0706	membrane insertase activity
BTL45_RS23925	COG0753	catalase activity
BTL45_RS23930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTL45_RS23935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BTL45_RS23945	COG2175	clavaminate synthase activity
BTL45_RS23950	COG1473	amidohydrolase
BTL45_RS23955	COG4608	Belongs to the ABC transporter superfamily
BTL45_RS23960	COG0444	Belongs to the ABC transporter superfamily
BTL45_RS23970	COG0601	transmembrane transport
BTL45_RS23975	COG0747	negative chemotaxis
BTL45_RS24015	COG0436	Aminotransferase
BTL45_RS24025	COG1278	Cold shock