locus-tag	class	description
CS344_RS00005	COG0445	tRNA wobble uridine modification
CS344_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CS344_RS00015	COG1192	Involved in chromosome partitioning
CS344_RS00025	COG1475	DNA binding
CS344_RS00030	COG0252	asparaginase activity
CS344_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS344_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS344_RS00075	COG0081	regulation of translation
CS344_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CS344_RS00085	COG0222	ribosome binding
CS344_RS00090	COG0085	RNA polymerase activity
CS344_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CS344_RS00130	COG1230	cation diffusion facilitator family transporter
CS344_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CS344_RS00145	COG0049	tRNA binding
CS344_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS344_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS344_RS00160	COG0051	transcription antitermination factor activity, RNA binding
CS344_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CS344_RS00175	COG0089	rRNA binding
CS344_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CS344_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CS344_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CS344_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CS344_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
CS344_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CS344_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CS344_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CS344_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CS344_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CS344_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CS344_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CS344_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CS344_RS00270	COG1841	ribosomal large subunit assembly
CS344_RS00275	COG0200	Binds to the 23S rRNA
CS344_RS00280	COG0201	protein transport
CS344_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS344_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CS344_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CS344_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CS344_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CS344_RS00310	COG0202	RNA polymerase activity
CS344_RS00315	COG0203	ribosomal protein L17
CS344_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
CS344_RS00325	COG1324	tolerance protein
CS344_RS00330	COG4232	protein-disulfide reductase activity
CS344_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CS344_RS00355	COG1333	cytochrome c biogenesis protein
CS344_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS344_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CS344_RS00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CS344_RS00395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CS344_RS00410	COG2814	Major facilitator Superfamily
CS344_RS00415	COG0629	single-stranded DNA binding
CS344_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
CS344_RS00460	COG0438	transferase activity, transferring glycosyl groups
CS344_RS00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS00510	COG2186	Transcriptional regulator
CS344_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS00535	COG1956	GAF domain-containing protein
CS344_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS00570	COG0531	amino acid
CS344_RS00605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CS344_RS00610	COG3568	Endonuclease Exonuclease Phosphatase
CS344_RS00615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS344_RS00625	COG0477	Major facilitator Superfamily
CS344_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS344_RS00645	COG0367	asparagine synthase
CS344_RS00665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CS344_RS00675	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS344_RS00710	COG0367	asparagine synthase
CS344_RS00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CS344_RS00740	COG0367	asparagine synthase
CS344_RS00750	COG0438	transferase activity, transferring glycosyl groups
CS344_RS00770	COG0438	transferase activity, transferring glycosyl groups
CS344_RS00775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS344_RS00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CS344_RS00810	COG0859	PFAM glycosyl transferase family 9
CS344_RS00825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CS344_RS00835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS344_RS00840	COG1127	ABC transporter
CS344_RS00860	COG1686	Belongs to the peptidase S11 family
CS344_RS00875	COG0321	lipoyl(octanoyl) transferase activity
CS344_RS00880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CS344_RS00900	COG2096	Adenosyltransferase
CS344_RS00910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CS344_RS00925	COG0523	cobalamin synthesis protein
CS344_RS00930	COG0735	belongs to the Fur family
CS344_RS00935	COG1121	(ABC) transporter
CS344_RS00945	COG0803	Belongs to the bacterial solute-binding protein 9 family
CS344_RS00955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CS344_RS00965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CS344_RS00975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CS344_RS00980	COG1560	Kdo2-lipid A biosynthetic process
CS344_RS00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CS344_RS01010	COG1950	PFAM Membrane protein of
CS344_RS01020	COG0583	DNA-binding transcription factor activity
CS344_RS01030	COG0477	Major facilitator Superfamily
CS344_RS01045	COG0617	tRNA 3'-terminal CCA addition
CS344_RS01055	COG0513	Belongs to the DEAD box helicase family
CS344_RS01065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS344_RS01070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS344_RS01090	COG0438	transferase activity, transferring glycosyl groups
CS344_RS01115	COG0640	Transcriptional regulator
CS344_RS01175	COG0583	DNA-binding transcription factor activity
CS344_RS01190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CS344_RS01195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS01200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS01215	COG0758	DNA mediated transformation
CS344_RS01220	COG1522	sequence-specific DNA binding
CS344_RS01230	COG0242	peptide deformylase activity
CS344_RS01235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS344_RS01245	COG0546	phosphoglycolate phosphatase activity
CS344_RS01265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS344_RS01270	COG1942	4-Oxalocrotonate Tautomerase
CS344_RS01275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS344_RS01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS344_RS01315	COG5000	phosphorelay sensor kinase activity
CS344_RS01320	COG2204	response regulator
CS344_RS01345	COG2068	MobA-Related Protein
CS344_RS01355	COG3473	Maleate cis-trans isomerase
CS344_RS01360	COG0596	Alpha beta hydrolase
CS344_RS01365	COG2309	aminopeptidase activity
CS344_RS01370	COG1335	isochorismatase
CS344_RS01395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS01420	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS344_RS01425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS01445	COG2226	methyltransferase
CS344_RS01460	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS01465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CS344_RS01470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CS344_RS01475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS344_RS01480	COG1054	Belongs to the UPF0176 family
CS344_RS01485	COG0588	phosphoglycerate mutase activity
CS344_RS01490	COG4942	peptidase
CS344_RS01495	COG0793	Belongs to the peptidase S41A family
CS344_RS01500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS344_RS01520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS344_RS01550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CS344_RS01555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CS344_RS01560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CS344_RS01565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CS344_RS01575	COG0142	geranyltranstransferase activity
CS344_RS01585	COG0583	DNA-binding transcription factor activity
CS344_RS01595	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CS344_RS01600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS01615	COG2994	toxin metabolic process
CS344_RS01625	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
CS344_RS01630	COG2274	protein secretion by the type I secretion system
CS344_RS01635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS01640	COG1538	Outer membrane efflux protein
CS344_RS01655	COG0765	amino acid transport
CS344_RS01660	COG0765	amino acid transport
CS344_RS01665	COG1126	abc transporter atp-binding protein
CS344_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS01695	COG1802	Transcriptional regulator
CS344_RS01710	COG1802	Transcriptional regulator
CS344_RS01720	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS01730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS01750	COG0028	Belongs to the TPP enzyme family
CS344_RS01760	COG0583	DNA-binding transcription factor activity
CS344_RS01765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS01770	COG2301	Belongs to the HpcH HpaI aldolase family
CS344_RS01775	COG2188	Transcriptional regulator
CS344_RS01810	COG0583	DNA-binding transcription factor activity
CS344_RS01835	COG0583	DNA-binding transcription factor activity
CS344_RS01840	COG1024	Enoyl-CoA hydratase
CS344_RS01875	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS01890	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS01915	COG0745	RESPONSE REGULATOR receiver
CS344_RS01950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CS344_RS01955	COG2890	protein-(glutamine-N5) methyltransferase activity
CS344_RS01960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CS344_RS01970	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02005	COG1464	Belongs to the NlpA lipoprotein family
CS344_RS02040	COG4211	Belongs to the binding-protein-dependent transport system permease family
CS344_RS02045	COG0583	DNA-binding transcription factor activity
CS344_RS02050	COG0683	leucine binding
CS344_RS02055	COG0154	amidase activity
CS344_RS02060	COG0288	reversible hydration of carbon dioxide
CS344_RS02080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS344_RS02095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS344_RS02105	COG1414	Transcriptional regulator
CS344_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS02115	COG2031	fatty acid transporter
CS344_RS02120	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS02130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CS344_RS02135	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CS344_RS02145	COG4257	antibiotic catabolic process
CS344_RS02150	COG2808	Putative FMN-binding domain
CS344_RS02155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS344_RS02160	COG0747	negative chemotaxis
CS344_RS02165	COG0657	acetylesterase activity
CS344_RS02175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS344_RS02180	COG2207	Transcriptional regulator
CS344_RS02190	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CS344_RS02195	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CS344_RS02205	COG1538	Outer membrane efflux protein
CS344_RS02220	COG0583	DNA-binding transcription factor activity
CS344_RS02225	COG0628	permease
CS344_RS02235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS344_RS02240	COG0251	oxidation-reduction process
CS344_RS02250	COG0330	HflC and HflK could
CS344_RS02255	COG3422	double-strand break repair
CS344_RS02270	COG0583	DNA-binding transcription factor activity
CS344_RS02305	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02310	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS02315	COG1414	Transcriptional regulator
CS344_RS02320	COG1024	Enoyl-CoA hydratase
CS344_RS02325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS02335	COG0604	alcohol dehydrogenase
CS344_RS02340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02345	COG0583	DNA-binding transcription factor activity
CS344_RS02355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02370	COG0251	oxidation-reduction process
CS344_RS02375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS344_RS02375	COG1017	nitric oxide dioxygenase activity
CS344_RS02380	COG2031	fatty acid transporter
CS344_RS02410	COG1278	Cold shock
CS344_RS02415	COG0583	DNA-binding transcription factor activity
CS344_RS02420	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02425	COG3119	arylsulfatase activity
CS344_RS02440	COG1228	amidohydrolase
CS344_RS02445	COG0523	cobalamin synthesis protein
CS344_RS02450	COG1819	glycosyl
CS344_RS02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS344_RS02495	COG1204	response to ionizing radiation
CS344_RS02520	COG0326	Molecular chaperone. Has ATPase activity
CS344_RS02525	COG0625	glutathione transferase activity
CS344_RS02540	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS344_RS02545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CS344_RS02550	COG1652	LysM domain
CS344_RS02575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS344_RS02615	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS02670	COG0583	DNA-binding transcription factor activity
CS344_RS02675	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02685	COG1024	Enoyl-CoA hydratase
CS344_RS02690	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02715	COG0028	Belongs to the TPP enzyme family
CS344_RS02720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02725	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS02725	COG1024	Enoyl-CoA hydratase
CS344_RS02730	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02735	COG1414	Transcriptional regulator
CS344_RS02755	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS02760	COG1609	Transcriptional regulator
CS344_RS02770	COG3976	FMN-binding domain protein
CS344_RS02770	COG1053	succinate dehydrogenase
CS344_RS02805	COG0683	leucine binding
CS344_RS02815	COG1309	transcriptional regulator
CS344_RS02835	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS02840	COG1960	acyl-CoA dehydrogenase activity
CS344_RS02845	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS02850	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS02860	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CS344_RS02870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CS344_RS02875	COG1053	succinate dehydrogenase
CS344_RS02885	COG2030	dehydratase
CS344_RS02895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS02905	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS02930	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS02950	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS02950	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS344_RS02965	COG0427	acetyl-CoA hydrolase
CS344_RS02970	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS02985	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CS344_RS02990	COG1960	acyl-CoA dehydrogenase activity
CS344_RS03005	COG0183	Belongs to the thiolase family
CS344_RS03010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS344_RS03020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS03025	COG0583	DNA-binding transcription factor activity
CS344_RS03030	COG1960	acyl-CoA dehydrogenase activity
CS344_RS03045	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CS344_RS03070	COG1309	transcriptional regulator
CS344_RS03080	COG1024	Enoyl-CoA hydratase
CS344_RS03100	COG1024	Enoyl-CoA hydratase
CS344_RS03105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS03110	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03115	COG1454	alcohol dehydrogenase
CS344_RS03120	COG1024	Enoyl-CoA hydratase
CS344_RS03140	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS03145	COG0431	NADPH-dependent FMN reductase
CS344_RS03150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS03155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS344_RS03170	COG1414	Transcriptional regulator
CS344_RS03175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS344_RS03180	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS03185	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03190	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS03200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS03210	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03235	COG1960	acyl-CoA dehydrogenase activity
CS344_RS03260	COG1024	Enoyl-CoA hydratase
CS344_RS03270	COG1960	acyl-CoA dehydrogenase activity
CS344_RS03275	COG1024	Enoyl-CoA hydratase
CS344_RS03280	COG0183	Belongs to the thiolase family
CS344_RS03285	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03300	COG0583	DNA-binding transcription factor activity
CS344_RS03305	COG2267	carboxylic ester hydrolase activity
CS344_RS03320	COG0625	glutathione transferase activity
CS344_RS03325	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03335	COG2186	Transcriptional regulator
CS344_RS03340	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS03345	COG0626	cystathionine gamma-synthase activity
CS344_RS03385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS03390	COG0436	Aminotransferase
CS344_RS03395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS03400	COG0765	amino acid transport
CS344_RS03410	COG1473	amidohydrolase
CS344_RS03415	COG1414	Transcriptional regulator
CS344_RS03425	COG0154	amidase activity
CS344_RS03485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS03500	COG3135	benzoate transporter
CS344_RS03525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS344_RS03530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS03535	COG1335	isochorismatase
CS344_RS03550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS03585	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03590	COG0633	Ferredoxin
CS344_RS03590	COG0543	2 iron, 2 sulfur cluster binding
CS344_RS03595	COG4638	Rieske (2fe-2S)
CS344_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS03615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS344_RS03635	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS03640	COG3384	dioxygenase
CS344_RS03650	COG3971	2-oxopent-4-enoate hydratase activity
CS344_RS03705	COG1024	Enoyl-CoA hydratase
CS344_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS03715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS03730	COG1960	acyl-CoA dehydrogenase activity
CS344_RS03775	COG0183	Belongs to the thiolase family
CS344_RS03780	COG2030	dehydratase
CS344_RS03790	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS03830	COG1459	type II secretion system
CS344_RS03835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS344_RS03840	COG3409	Peptidoglycan-binding domain 1 protein
CS344_RS03840	COG3267	Type II secretory pathway component ExeA
CS344_RS03850	COG1450	Type ii and iii secretion system protein
CS344_RS03915	COG5444	nuclease activity
CS344_RS04025	COG0387	Pfam Sodium calcium exchanger
CS344_RS04035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS344_RS04085	COG4772	TonB-dependent receptor
CS344_RS04095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS344_RS04120	COG1054	Belongs to the UPF0176 family
CS344_RS04135	COG0489	protein tyrosine kinase activity
CS344_RS04180	COG2081	HI0933 family
CS344_RS04185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS344_RS04195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS344_RS04200	COG0509	glycine decarboxylation via glycine cleavage system
CS344_RS04205	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS344_RS04205	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS344_RS04225	COG1024	Enoyl-CoA hydratase
CS344_RS04245	COG4172	Belongs to the ABC transporter superfamily
CS344_RS04250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS04255	COG0601	transmembrane transport
CS344_RS04260	COG0747	negative chemotaxis
CS344_RS04270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS344_RS04275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS04300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS344_RS04305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS344_RS04320	COG0438	transferase activity, transferring glycosyl groups
CS344_RS04335	COG0438	transferase activity, transferring glycosyl groups
CS344_RS04340	COG0438	transferase activity, transferring glycosyl groups
CS344_RS04345	COG0166	Belongs to the GPI family
CS344_RS04360	COG0277	FAD linked oxidase domain protein
CS344_RS04365	COG0745	RESPONSE REGULATOR receiver
CS344_RS04370	COG0642	Histidine kinase
CS344_RS04375	COG1368	sulfuric ester hydrolase activity
CS344_RS04410	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CS344_RS04425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CS344_RS04455	COG0012	GTP binding
CS344_RS04465	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CS344_RS04485	COG0556	nucleotide-excision repair
CS344_RS04525	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS04530	COG1309	transcriptional regulator
CS344_RS04540	COG2814	Major facilitator Superfamily
CS344_RS04565	COG0281	malic enzyme
CS344_RS04565	COG0280	phosphate acetyltransferase
CS344_RS04575	COG0601	transmembrane transport
CS344_RS04580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS04585	COG4172	Belongs to the ABC transporter superfamily
CS344_RS04590	COG0747	negative chemotaxis
CS344_RS04600	COG0583	DNA-binding transcription factor activity
CS344_RS04615	COG0640	Transcriptional regulator
CS344_RS04630	COG3135	benzoate transporter
CS344_RS04635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS344_RS04640	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CS344_RS04645	COG0742	ribosomal rna small subunit methyltransferase
CS344_RS04660	COG3639	organic phosphonate transmembrane transporter activity
CS344_RS04665	COG3639	organic phosphonate transmembrane transporter activity
CS344_RS04670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS344_RS04695	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CS344_RS04700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS344_RS04710	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CS344_RS04715	COG1546	Belongs to the CinA family
CS344_RS04715	COG1058	Belongs to the CinA family
CS344_RS04720	COG0284	orotidine-5'-phosphate decarboxylase activity
CS344_RS04725	COG1252	NADH dehydrogenase
CS344_RS04740	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS04750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CS344_RS04770	COG1053	succinate dehydrogenase
CS344_RS04785	COG0583	DNA-binding transcription factor activity
CS344_RS04790	COG1053	succinate dehydrogenase
CS344_RS04795	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS04800	COG1414	Transcriptional regulator
CS344_RS04815	COG1335	isochorismatase
CS344_RS04830	COG0405	Gamma-glutamyltransferase
CS344_RS04845	COG1960	acyl-CoA dehydrogenase activity
CS344_RS04850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS04855	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS04860	COG0583	DNA-binding transcription factor activity
CS344_RS04885	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS04890	COG0583	DNA-binding transcription factor activity
CS344_RS04895	COG2199	diguanylate cyclase activity
CS344_RS04920	COG3842	ATPase activity
CS344_RS04945	COG1024	Enoyl-CoA hydratase
CS344_RS04945	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS04950	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS04965	COG4172	Belongs to the ABC transporter superfamily
CS344_RS04975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS05000	COG2423	ornithine cyclodeaminase activity
CS344_RS05010	COG0473	3-isopropylmalate dehydrogenase activity
CS344_RS05015	COG0066	3-isopropylmalate dehydratase activity
CS344_RS05020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS344_RS05030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS05040	COG0583	DNA-binding transcription factor activity
CS344_RS05055	COG0583	DNA-binding transcription factor activity
CS344_RS05065	COG1024	Enoyl-CoA hydratase
CS344_RS05075	COG2084	Dehydrogenase
CS344_RS05095	COG1850	ribulose-bisphosphate carboxylase activity
CS344_RS05105	COG0583	DNA-binding transcription factor activity
CS344_RS05110	COG1024	Enoyl-CoA hydratase
CS344_RS05135	COG3842	ATPase activity
CS344_RS05140	COG1177	transmembrane transport
CS344_RS05155	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05160	COG3386	PFAM SMP-30 Gluconolaconase
CS344_RS05170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS344_RS05190	COG0583	DNA-binding transcription factor activity
CS344_RS05200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS05215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS05255	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS05290	COG1802	Transcriptional regulator
CS344_RS05295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS05330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05345	COG0183	Belongs to the thiolase family
CS344_RS05350	COG1024	Enoyl-CoA hydratase
CS344_RS05360	COG1024	Enoyl-CoA hydratase
CS344_RS05365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05370	COG0583	DNA-binding transcription factor activity
CS344_RS05375	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05395	COG0583	DNA-binding transcription factor activity
CS344_RS05400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05405	COG1960	acyl-CoA dehydrogenase activity
CS344_RS05410	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CS344_RS05420	COG4191	Histidine kinase
CS344_RS05425	COG4566	intracellular signal transduction
CS344_RS05455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS05465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS344_RS05485	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05510	COG0583	DNA-binding transcription factor activity
CS344_RS05530	COG1024	Enoyl-CoA hydratase
CS344_RS05535	COG1024	Enoyl-CoA hydratase
CS344_RS05540	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS05545	COG1960	acyl-CoA dehydrogenase activity
CS344_RS05580	COG3795	YCII-related domain
CS344_RS05585	COG2188	Transcriptional regulator
CS344_RS05605	COG0154	amidase activity
CS344_RS05610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05615	COG1024	Enoyl-CoA hydratase
CS344_RS05625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS05640	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS05645	COG1414	Transcriptional regulator
CS344_RS05660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS344_RS05665	COG0251	oxidation-reduction process
CS344_RS05670	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS05690	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS05695	COG0583	DNA-binding transcription factor activity
CS344_RS05705	COG0590	tRNA wobble adenosine to inosine editing
CS344_RS05710	COG2807	transmembrane transport
CS344_RS05720	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05725	COG0154	amidase activity
CS344_RS05730	COG0307	riboflavin synthase, alpha
CS344_RS05735	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS05740	COG1522	sequence-specific DNA binding
CS344_RS05750	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS05760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS05770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS344_RS05780	COG1063	alcohol dehydrogenase
CS344_RS05800	COG1418	mRNA catabolic process
CS344_RS05805	COG1448	Aminotransferase
CS344_RS05810	COG1335	isochorismatase
CS344_RS05835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS05840	COG2274	protein secretion by the type I secretion system
CS344_RS05850	COG1538	Outer membrane efflux protein
CS344_RS05855	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS344_RS05855	COG0493	'glutamate synthase
CS344_RS05865	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CS344_RS05875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS05885	COG1309	transcriptional regulator
CS344_RS05890	COG1960	acyl-CoA dehydrogenase activity
CS344_RS05895	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS05900	COG2076	Multidrug Resistance protein
CS344_RS05905	COG1309	transcriptional regulator
CS344_RS05915	COG0583	DNA-binding transcription factor activity
CS344_RS05930	COG0840	transmembrane signaling receptor activity
CS344_RS05945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS05970	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS05980	COG1024	Enoyl-CoA hydratase
CS344_RS05990	COG2199	diguanylate cyclase activity
CS344_RS05990	COG2203	Gaf domain
CS344_RS06005	COG0456	acetyltransferase
CS344_RS06015	COG0154	amidase activity
CS344_RS06020	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS06020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS06030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS06045	COG3945	hemerythrin HHE cation binding domain
CS344_RS06060	COG2169	Transcriptional regulator
CS344_RS06060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS344_RS06080	COG1271	oxidase subunit
CS344_RS06085	COG1294	oxidase, subunit
CS344_RS06095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS06125	COG0596	Alpha beta hydrolase
CS344_RS06130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS344_RS06170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS344_RS06175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CS344_RS06185	COG2070	2-Nitropropane dioxygenase
CS344_RS06220	COG2900	Belongs to the SlyX family
CS344_RS06230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS344_RS06255	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS06260	COG0583	DNA-binding transcription factor activity
CS344_RS06265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS06275	COG0583	DNA-binding transcription factor activity
CS344_RS06300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CS344_RS06310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS344_RS06315	COG1845	cytochrome c oxidase, subunit III
CS344_RS06320	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS344_RS06325	COG0640	Transcriptional regulator
CS344_RS06375	COG4942	peptidase
CS344_RS06390	COG1666	GTP binding
CS344_RS06415	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS06425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS344_RS06430	COG1845	cytochrome c oxidase, subunit III
CS344_RS06435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS344_RS06440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CS344_RS06445	COG0477	Major facilitator Superfamily
CS344_RS06460	COG5006	permease, DMT superfamily
CS344_RS06480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CS344_RS06490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CS344_RS06495	COG3383	formate dehydrogenase (NAD+) activity
CS344_RS06515	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CS344_RS06520	COG0303	'Molybdopterin
CS344_RS06525	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS344_RS06535	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CS344_RS06550	COG0412	Dienelactone hydrolase
CS344_RS06560	COG0678	peroxiredoxin activity
CS344_RS06570	COG0697	spore germination
CS344_RS06615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS344_RS06620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CS344_RS06625	COG1335	isochorismatase
CS344_RS06630	COG0523	cobalamin synthesis protein
CS344_RS06660	COG1802	Transcriptional regulator
CS344_RS06680	COG0667	Aldo Keto reductase
CS344_RS06685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CS344_RS06690	COG4535	Mg2 and Co2 transporter CorC
CS344_RS06695	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CS344_RS06700	COG1702	phosphate starvation-inducible protein PhoH
CS344_RS06705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS344_RS06715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS344_RS06720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS344_RS06725	COG1862	Preprotein translocase
CS344_RS06730	COG0343	queuine tRNA-ribosyltransferase activity
CS344_RS06740	COG2027	D-alanyl-D-alanine carboxypeptidase
CS344_RS06780	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CS344_RS06785	COG0741	lytic transglycosylase activity
CS344_RS06795	COG0436	Aminotransferase
CS344_RS06815	COG2732	(Barnase) inhibitor
CS344_RS06820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CS344_RS06825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS344_RS06830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CS344_RS06840	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CS344_RS06845	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS344_RS06860	COG0625	glutathione transferase activity
CS344_RS06890	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CS344_RS06900	COG0306	phosphate transporter
CS344_RS06905	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS344_RS06915	COG0739	heme binding
CS344_RS06925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS344_RS06975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CS344_RS06985	COG2944	sequence-specific DNA binding
CS344_RS06995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CS344_RS07000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CS344_RS07005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CS344_RS07010	COG0009	L-threonylcarbamoyladenylate synthase
CS344_RS07015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS07020	COG1414	Transcriptional regulator
CS344_RS07035	COG0765	amino acid transport
CS344_RS07040	COG1126	abc transporter atp-binding protein
CS344_RS07045	COG0028	Belongs to the TPP enzyme family
CS344_RS07060	COG0028	Belongs to the TPP enzyme family
CS344_RS07065	COG0583	DNA-binding transcription factor activity
CS344_RS07070	COG4974	Belongs to the 'phage' integrase family
CS344_RS07075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CS344_RS07080	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CS344_RS07090	COG1686	Belongs to the peptidase S11 family
CS344_RS07100	COG2814	Major facilitator Superfamily
CS344_RS07110	COG1074	ATP-dependent DNA helicase activity
CS344_RS07120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS344_RS07135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS07140	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS344_RS07150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS07160	COG0505	Belongs to the CarA family
CS344_RS07165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CS344_RS07170	COG4221	oxidoreductase activity
CS344_RS07175	COG0406	alpha-ribazole phosphatase activity
CS344_RS07185	COG3842	ATPase activity
CS344_RS07205	COG2233	PERMEase
CS344_RS07210	COG0840	transmembrane signaling receptor activity
CS344_RS07215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS344_RS07220	COG1534	Rna-binding protein
CS344_RS07230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS344_RS07250	COG0248	Ppx GppA phosphatase
CS344_RS07290	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS07300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS07305	COG3620	sequence-specific DNA binding
CS344_RS07395	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS07430	COG2072	flavoprotein involved in K transport
CS344_RS07435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS07465	COG1137	ATPase activity
CS344_RS07475	COG0154	amidase activity
CS344_RS07480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS07495	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS07500	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS07505	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS07510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS07515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS07525	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS344_RS07535	COG1522	sequence-specific DNA binding
CS344_RS07540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS344_RS07545	COG1473	amidohydrolase
CS344_RS07550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS07555	COG4597	amino acid ABC transporter
CS344_RS07560	COG0765	amino acid transport
CS344_RS07565	COG1126	abc transporter atp-binding protein
CS344_RS07580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS344_RS07610	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS07625	COG2985	domain, Protein
CS344_RS07630	COG0583	DNA-binding transcription factor activity
CS344_RS07665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS344_RS07705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS344_RS07715	COG1132	(ABC) transporter
CS344_RS07740	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CS344_RS07750	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS07760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CS344_RS07770	COG0511	ligase activity, forming carbon-carbon bonds
CS344_RS07795	COG2188	Transcriptional regulator
CS344_RS07800	COG0439	Biotin carboxylase
CS344_RS07810	COG0511	ligase activity, forming carbon-carbon bonds
CS344_RS07825	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS07855	COG3971	2-oxopent-4-enoate hydratase activity
CS344_RS07860	COG0583	DNA-binding transcription factor activity
CS344_RS07875	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS344_RS07915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS344_RS07925	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS07965	COG0251	oxidation-reduction process
CS344_RS07970	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS08000	COG4789	Type iii secretion
CS344_RS08065	COG4669	(LipO)protein
CS344_RS08100	COG4790	Type iii secretion
CS344_RS08105	COG4794	Type iii secretion
CS344_RS08110	COG4791	protein targeting
CS344_RS08115	COG4792	protein secretion
CS344_RS08130	COG1595	DNA-templated transcription, initiation
CS344_RS08150	COG2208	phosphoserine phosphatase activity
CS344_RS08150	COG2770	Histidine kinase
CS344_RS08160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS344_RS08165	COG2172	sigma factor antagonist activity
CS344_RS08170	COG1366	Belongs to the anti-sigma-factor antagonist family
CS344_RS08175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS344_RS08220	COG2321	neutral zinc metallopeptidase
CS344_RS08225	COG0009	L-threonylcarbamoyladenylate synthase
CS344_RS08230	COG1994	Peptidase M50
CS344_RS08235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS08240	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CS344_RS08245	COG3539	Fimbrial protein
CS344_RS08255	COG2850	peptidyl-arginine hydroxylation
CS344_RS08265	COG3360	Dodecin
CS344_RS08300	COG0668	transmembrane transport
CS344_RS08320	COG0483	inositol monophosphate 1-phosphatase activity
CS344_RS08325	COG1253	flavin adenine dinucleotide binding
CS344_RS08335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS344_RS08345	COG3063	Type IV pilus biogenesis stability protein PilW
CS344_RS08360	COG0825	malonyl-CoA metabolic process
CS344_RS08365	COG0037	tRNA processing
CS344_RS08370	COG0527	aspartate kinase activity
CS344_RS08390	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS08395	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS08395	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS08410	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS344_RS08420	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS08430	COG0583	DNA-binding transcription factor activity
CS344_RS08455	COG3842	ATPase activity
CS344_RS08465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS344_RS08465	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS08470	COG1414	Transcriptional regulator
CS344_RS08475	COG1832	CoA-binding protein
CS344_RS08485	COG0251	oxidation-reduction process
CS344_RS08510	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS08520	COG1215	transferase activity, transferring glycosyl groups
CS344_RS08525	COG1649	PFAM Uncharacterised BCR, COG1649
CS344_RS08525	COG0726	polysaccharide deacetylase
CS344_RS08545	COG1846	Transcriptional regulator
CS344_RS08570	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS344_RS08570	COG2010	Cytochrome c
CS344_RS08575	COG2080	2 iron, 2 sulfur cluster binding
CS344_RS08580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS344_RS08585	COG3473	Maleate cis-trans isomerase
CS344_RS08590	COG0596	Alpha beta hydrolase
CS344_RS08595	COG2309	aminopeptidase activity
CS344_RS08600	COG1335	isochorismatase
CS344_RS08605	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS344_RS08605	COG2010	Cytochrome c
CS344_RS08610	COG1017	nitric oxide dioxygenase activity
CS344_RS08610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS344_RS08625	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS08635	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS08645	COG0183	Belongs to the thiolase family
CS344_RS08650	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS08650	COG1024	Enoyl-CoA hydratase
CS344_RS08665	COG0183	Belongs to the thiolase family
CS344_RS08680	COG2197	response regulator
CS344_RS08695	COG0166	Belongs to the GPI family
CS344_RS08700	COG1045	serine acetyltransferase
CS344_RS08710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS344_RS08715	COG0483	inositol monophosphate 1-phosphatase activity
CS344_RS08725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS344_RS08740	COG0210	DNA helicase
CS344_RS08745	COG0598	Magnesium transport protein CorA
CS344_RS08755	COG0747	negative chemotaxis
CS344_RS08760	COG0601	transmembrane transport
CS344_RS08765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS08770	COG4172	Belongs to the ABC transporter superfamily
CS344_RS08775	COG1846	Transcriptional regulator
CS344_RS08820	COG4964	Belongs to the GSP D family
CS344_RS08885	COG3474	cytochrome
CS344_RS08890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CS344_RS08905	COG3384	dioxygenase
CS344_RS08910	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS344_RS08930	COG2885	chlorophyll binding
CS344_RS08965	COG0697	spore germination
CS344_RS08970	COG0730	response to heat
CS344_RS08985	COG3264	Mechanosensitive ion channel
CS344_RS08985	COG1511	domain protein
CS344_RS08990	COG0583	DNA-binding transcription factor activity
CS344_RS08995	COG0427	acetyl-CoA hydrolase
CS344_RS09000	COG0385	Bile acid
CS344_RS09040	COG3012	SEC-C Motif Domain Protein
CS344_RS09050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS09055	COG0154	amidase activity
CS344_RS09065	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CS344_RS09080	COG0495	leucyl-tRNA aminoacylation
CS344_RS09085	COG2814	Major facilitator Superfamily
CS344_RS09105	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CS344_RS09110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CS344_RS09115	COG2814	Major facilitator Superfamily
CS344_RS09120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CS344_RS09130	COG4176	ABC-type proline glycine betaine transport system permease component
CS344_RS09140	COG1942	4-Oxalocrotonate Tautomerase
CS344_RS09145	COG0183	Belongs to the thiolase family
CS344_RS09155	COG1802	Transcriptional regulator
CS344_RS09165	COG1024	Enoyl-CoA hydratase
CS344_RS09170	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS09180	COG2032	superoxide dismutase activity
CS344_RS09195	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS344_RS09220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS09225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS344_RS09235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CS344_RS09240	COG0736	holo-[acyl-carrier-protein] synthase activity
CS344_RS09255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CS344_RS09265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS344_RS09265	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS344_RS09270	COG2224	Isocitrate lyase
CS344_RS09280	COG1346	cytolysis
CS344_RS09285	COG1380	Effector of murein hydrolase LrgA
CS344_RS09290	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CS344_RS09290	COG4106	trans-aconitate 2-methyltransferase activity
CS344_RS09300	COG0156	8-amino-7-oxononanoate synthase activity
CS344_RS09320	COG3278	Belongs to the heme-copper respiratory oxidase family
CS344_RS09365	COG1131	(ABC) transporter
CS344_RS09370	COG0842	Transport permease protein
CS344_RS09375	COG0628	permease
CS344_RS09385	COG0583	DNA-binding transcription factor activity
CS344_RS09390	COG2814	Major facilitator Superfamily
CS344_RS09395	COG2841	Protein conserved in bacteria
CS344_RS09420	COG0765	amino acid transport
CS344_RS09425	COG0765	amino acid transport
CS344_RS09430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS09465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS09470	COG1595	DNA-templated transcription, initiation
CS344_RS09480	COG3530	Putative quorum-sensing-regulated virulence factor
CS344_RS09485	COG0494	nUDIX hydrolase
CS344_RS09500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS344_RS09505	COG0542	response to heat
CS344_RS09510	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS09515	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS09520	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS09530	COG5441	Belongs to the UPF0261 family
CS344_RS09535	COG5564	TIM-barrel signal transduction protein
CS344_RS09550	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS344_RS09565	COG1477	protein flavinylation
CS344_RS09585	COG1131	(ABC) transporter
CS344_RS09590	COG0842	Transport permease protein
CS344_RS09600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CS344_RS09605	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS344_RS09605	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS344_RS09610	COG1562	ergosterol biosynthetic process
CS344_RS09615	COG1562	ergosterol biosynthetic process
CS344_RS09620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS344_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS09640	COG2304	oxidoreductase activity
CS344_RS09660	COG0534	Mate efflux family protein
CS344_RS09675	COG3483	tryptophan 2,3-dioxygenase activity
CS344_RS09680	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CS344_RS09685	COG2003	Belongs to the UPF0758 family
CS344_RS09690	COG1047	Peptidyl-prolyl cis-trans
CS344_RS09695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CS344_RS09700	COG0625	glutathione transferase activity
CS344_RS09720	COG0523	cobalamin synthesis protein
CS344_RS09730	COG0583	DNA-binding transcription factor activity
CS344_RS09740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CS344_RS09745	COG1187	pseudouridine synthase activity
CS344_RS09750	COG0779	Required for maturation of 30S ribosomal subunits
CS344_RS09755	COG0195	Participates in both transcription termination and antitermination
CS344_RS09755	COG2251	uridine kinase activity
CS344_RS09760	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CS344_RS09765	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CS344_RS09770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CS344_RS09790	COG1611	Belongs to the LOG family
CS344_RS09805	COG0412	Dienelactone hydrolase
CS344_RS09810	COG1283	sodium-dependent phosphate transmembrane transporter activity
CS344_RS09815	COG1760	l-serine dehydratase
CS344_RS09820	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CS344_RS09825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CS344_RS09835	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CS344_RS09860	COG2311	Membrane
CS344_RS09870	COG2358	TRAP transporter, solute receptor (TAXI family
CS344_RS09875	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS344_RS09890	COG0456	acetyltransferase
CS344_RS09905	COG5285	phytanoyl-CoA dioxygenase
CS344_RS09915	COG3395	kinase activity
CS344_RS09920	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS344_RS09945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS09970	COG0747	negative chemotaxis
CS344_RS09975	COG0601	transmembrane transport
CS344_RS09980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS09985	COG4172	Belongs to the ABC transporter superfamily
CS344_RS10035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CS344_RS10040	COG0425	Belongs to the sulfur carrier protein TusA family
CS344_RS10050	COG0228	four-way junction DNA binding
CS344_RS10065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CS344_RS10075	COG0642	Histidine kinase
CS344_RS10090	COG0525	valine-tRNA ligase activity
CS344_RS10095	COG0105	UTP biosynthetic process
CS344_RS10100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CS344_RS10120	COG2976	Protein conserved in bacteria
CS344_RS10125	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS344_RS10130	COG1160	GTP binding
CS344_RS10140	COG1923	regulation of RNA biosynthetic process
CS344_RS10145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CS344_RS10150	COG0330	HflC and HflK could
CS344_RS10155	COG0330	HflC and HflK could
CS344_RS10165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CS344_RS10170	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CS344_RS10175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CS344_RS10185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS344_RS10195	COG4680	protein conserved in bacteria
CS344_RS10245	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS10255	COG4638	Rieske (2fe-2S)
CS344_RS10265	COG1024	Enoyl-CoA hydratase
CS344_RS10275	COG0633	Ferredoxin
CS344_RS10280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS10295	COG0183	Belongs to the thiolase family
CS344_RS10305	COG4692	amylo-alpha-1,6-glucosidase activity
CS344_RS10310	COG0583	DNA-binding transcription factor activity
CS344_RS10325	COG0028	Belongs to the TPP enzyme family
CS344_RS10330	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS10335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS10355	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CS344_RS10365	COG3829	transcription factor binding
CS344_RS10395	COG0833	amino acid
CS344_RS10410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS344_RS10415	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CS344_RS10420	COG0840	transmembrane signaling receptor activity
CS344_RS10450	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS10455	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS10490	COG5265	(ABC) transporter
CS344_RS10500	COG0667	Aldo Keto reductase
CS344_RS10515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS344_RS10555	COG1959	2 iron, 2 sulfur cluster binding
CS344_RS10560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS10565	COG0587	DNA-directed DNA polymerase activity
CS344_RS10580	COG0400	carboxylic ester hydrolase activity
CS344_RS10590	COG1566	PFAM secretion protein HlyD family protein
CS344_RS10615	COG0235	Class ii aldolase
CS344_RS10620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS10625	COG0720	synthase
CS344_RS10630	COG0602	queuosine metabolic process
CS344_RS10655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS10690	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS10720	COG3842	ATPase activity
CS344_RS10730	COG0395	ABC-type sugar transport system, permease component
CS344_RS10760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS10765	COG0420	3'-5' exonuclease activity
CS344_RS10775	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS10780	COG2111	Na H antiporter
CS344_RS10780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CS344_RS10785	COG1006	Multisubunit Na H antiporter MnhC subunit
CS344_RS10790	COG0651	ATP synthesis coupled electron transport
CS344_RS10795	COG1863	multisubunit Na H antiporter MnhE subunit
CS344_RS10800	COG2212	antiporter activity
CS344_RS10820	COG0590	tRNA wobble adenosine to inosine editing
CS344_RS10825	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS344_RS10830	COG1024	Enoyl-CoA hydratase
CS344_RS10835	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS10845	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS10850	COG0488	(ABC) transporter
CS344_RS10880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS344_RS10885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS344_RS10890	COG2252	PERMEase
CS344_RS10895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CS344_RS10900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CS344_RS10935	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CS344_RS10940	COG0789	Transcriptional regulator
CS344_RS10950	COG0678	peroxiredoxin activity
CS344_RS10950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS344_RS10960	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CS344_RS10965	COG0584	glycerophosphoryl diester phosphodiesterase
CS344_RS10970	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS344_RS10980	COG4181	ATPase activity
CS344_RS11005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS11030	COG2205	protein histidine kinase activity
CS344_RS11030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS11035	COG2197	response regulator
CS344_RS11040	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS344_RS11040	COG3210	domain, Protein
CS344_RS11040	COG3064	Membrane
CS344_RS11050	COG3121	Chaperone
CS344_RS11055	COG3188	usher protein
CS344_RS11060	COG3539	Fimbrial protein
CS344_RS11065	COG2831	hemolysin activation secretion protein
CS344_RS11080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS11105	COG0583	DNA-binding transcription factor activity
CS344_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS11130	COG0765	amino acid transport
CS344_RS11135	COG1126	abc transporter atp-binding protein
CS344_RS11140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS344_RS11145	COG1758	RNA polymerase activity
CS344_RS11150	COG0194	GDP metabolic process
CS344_RS11155	COG3258	Cytochrome c
CS344_RS11160	COG2863	cytochrome
CS344_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS11170	COG0791	NLP P60 protein
CS344_RS11175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS344_RS11195	COG1561	YicC-like family, N-terminal region
CS344_RS11200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CS344_RS11220	COG5002	protein histidine kinase activity
CS344_RS11220	COG5001	Diguanylate cyclase
CS344_RS11225	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CS344_RS11230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS344_RS11235	COG0174	glutamine synthetase
CS344_RS11245	COG2204	response regulator
CS344_RS11250	COG0583	DNA-binding transcription factor activity
CS344_RS11255	COG1741	Belongs to the pirin family
CS344_RS11260	COG1741	Belongs to the pirin family
CS344_RS11265	COG3842	ATPase activity
CS344_RS11270	COG1178	ABC-type Fe3 transport system permease component
CS344_RS11275	COG1840	ABC-type Fe3 transport system, periplasmic component
CS344_RS11285	COG0583	DNA-binding transcription factor activity
CS344_RS11290	COG2814	Major facilitator Superfamily
CS344_RS11295	COG0656	L-ascorbic acid biosynthetic process
CS344_RS11310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CS344_RS11315	COG0583	DNA-binding transcription factor activity
CS344_RS11330	COG0783	Belongs to the Dps family
CS344_RS11345	COG0463	Glycosyl transferase, family 2
CS344_RS11365	COG0438	transferase activity, transferring glycosyl groups
CS344_RS11380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS344_RS11400	COG0300	oxidoreductase activity
CS344_RS11410	COG0156	8-amino-7-oxononanoate synthase activity
CS344_RS11415	COG0604	alcohol dehydrogenase
CS344_RS11415	COG3321	synthase
CS344_RS11415	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS11430	COG3842	ATPase activity
CS344_RS11435	COG0395	ABC-type sugar transport system, permease component
CS344_RS11440	COG1175	transmembrane transport
CS344_RS11445	COG1653	transport
CS344_RS11455	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CS344_RS11465	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS11485	COG1794	racemase activity, acting on amino acids and derivatives
CS344_RS11490	COG0625	glutathione transferase activity
CS344_RS11495	COG2133	pyrroloquinoline quinone binding
CS344_RS11505	COG0697	spore germination
CS344_RS11510	COG2363	Small membrane protein
CS344_RS11525	COG1464	Belongs to the NlpA lipoprotein family
CS344_RS11535	COG0688	phosphatidylethanolamine metabolic process
CS344_RS11550	COG0095	Lipoate-protein ligase
CS344_RS11565	COG0625	glutathione transferase activity
CS344_RS11570	COG0386	Belongs to the glutathione peroxidase family
CS344_RS11590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS11610	COG2259	Doxx family
CS344_RS11625	COG0667	Aldo Keto reductase
CS344_RS11670	COG1640	4-alpha-glucanotransferase
CS344_RS11685	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS344_RS11695	COG0366	Alpha amylase catalytic
CS344_RS11700	COG0297	glycogen (starch) synthase activity
CS344_RS11710	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS344_RS11715	COG2204	response regulator
CS344_RS11720	COG2204	response regulator
CS344_RS11725	COG0028	Belongs to the TPP enzyme family
CS344_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS11785	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CS344_RS11790	COG4575	ribosome binding
CS344_RS11825	COG0392	lysyltransferase activity
CS344_RS11830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS344_RS11835	COG3568	Endonuclease Exonuclease Phosphatase
CS344_RS11845	COG1695	Transcriptional regulator
CS344_RS11855	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS11865	COG0583	DNA-binding transcription factor activity
CS344_RS11880	COG1802	Transcriptional regulator
CS344_RS11890	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS11900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS11905	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS11915	COG0066	3-isopropylmalate dehydratase activity
CS344_RS11920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS344_RS11925	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS11930	COG4948	Mandelate Racemase Muconate Lactonizing
CS344_RS11960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS344_RS11970	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CS344_RS11990	COG4133	protoheme IX ABC transporter activity
CS344_RS11995	COG3005	denitrification pathway
CS344_RS12000	COG3043	anaerobic respiration
CS344_RS12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS12025	COG0765	amino acid transport
CS344_RS12030	COG1126	abc transporter atp-binding protein
CS344_RS12035	COG0330	HflC and HflK could
CS344_RS12045	COG1454	alcohol dehydrogenase
CS344_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS12050	COG5001	Diguanylate cyclase
CS344_RS12050	COG3706	GGDEF domain
CS344_RS12050	COG4251	negative regulation of phosphorylation
CS344_RS12050	COG2203	Gaf domain
CS344_RS12060	COG0583	DNA-binding transcription factor activity
CS344_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS12095	COG0431	NADPH-dependent FMN reductase
CS344_RS12100	COG0583	DNA-binding transcription factor activity
CS344_RS12120	COG0824	Thioesterase
CS344_RS12125	COG1454	alcohol dehydrogenase
CS344_RS12130	COG0183	Belongs to the thiolase family
CS344_RS12135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS12135	COG1024	Enoyl-CoA hydratase
CS344_RS12140	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS12150	COG1024	Enoyl-CoA hydratase
CS344_RS12155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS12160	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS12165	COG0583	DNA-binding transcription factor activity
CS344_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS12185	COG0183	Belongs to the thiolase family
CS344_RS12190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS12195	COG1414	Transcriptional regulator
CS344_RS12205	COG3119	arylsulfatase activity
CS344_RS12220	COG0625	glutathione transferase activity
CS344_RS12225	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CS344_RS12230	COG2944	sequence-specific DNA binding
CS344_RS12240	COG2197	response regulator
CS344_RS12260	COG3119	arylsulfatase activity
CS344_RS12295	COG0714	Associated with various cellular activities
CS344_RS12300	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS344_RS12315	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS12320	COG0861	Integral membrane protein TerC family
CS344_RS12350	COG1228	amidohydrolase
CS344_RS12360	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS344_RS12370	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS344_RS12390	COG0583	DNA-binding transcription factor activity
CS344_RS12395	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS12420	COG2188	Transcriptional regulator
CS344_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS12435	COG1414	Transcriptional regulator
CS344_RS12440	COG3842	ATPase activity
CS344_RS12450	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS344_RS12455	COG0395	ABC-type sugar transport system, permease component
CS344_RS12470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS12490	COG0439	Biotin carboxylase
CS344_RS12495	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CS344_RS12500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS12515	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS12525	COG0583	DNA-binding transcription factor activity
CS344_RS12535	COG2814	Major facilitator Superfamily
CS344_RS12550	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS344_RS12565	COG2084	Dehydrogenase
CS344_RS12580	COG1253	flavin adenine dinucleotide binding
CS344_RS12595	COG2988	succinylglutamate desuccinylase activity
CS344_RS12620	COG0861	Integral membrane protein TerC family
CS344_RS12630	COG1595	DNA-templated transcription, initiation
CS344_RS12645	COG0076	glutamate decarboxylase activity
CS344_RS12650	COG2985	domain, Protein
CS344_RS12660	COG3189	MarR family transcriptional regulator
CS344_RS12670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS12680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS12680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS12690	COG0028	Belongs to the TPP enzyme family
CS344_RS12700	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS12705	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS344_RS12710	COG0010	Belongs to the arginase family
CS344_RS12715	COG1126	abc transporter atp-binding protein
CS344_RS12720	COG0765	amino acid transport
CS344_RS12725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS12740	COG0084	hydrolase, TatD family'
CS344_RS12745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS344_RS12750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS344_RS12755	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CS344_RS12780	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CS344_RS12785	COG1960	acyl-CoA dehydrogenase activity
CS344_RS12795	COG2867	negative regulation of translational initiation
CS344_RS12800	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CS344_RS12805	COG3706	GGDEF domain
CS344_RS12810	COG0330	HflC and HflK could
CS344_RS12820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS344_RS12820	COG0519	Catalyzes the synthesis of GMP from XMP
CS344_RS12835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS344_RS12840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CS344_RS12855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CS344_RS12865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CS344_RS12870	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS344_RS12875	COG0750	zinc metalloprotease
CS344_RS12880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CS344_RS12890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CS344_RS12895	COG0233	cytoplasmic translational termination
CS344_RS12900	COG0528	UMP kinase activity
CS344_RS12905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CS344_RS12910	COG0052	Belongs to the universal ribosomal protein uS2 family
CS344_RS12915	COG0024	Methionine aminopeptidase
CS344_RS12920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CS344_RS12950	COG0285	dihydrofolate synthase activity
CS344_RS12980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CS344_RS12990	COG1677	Flagellar hook-basal body complex protein FliE
CS344_RS13000	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS344_RS13005	COG1317	bacterial-type flagellum organization
CS344_RS13010	COG1157	protein secretion by the type III secretion system
CS344_RS13025	COG1580	Controls the rotational direction of flagella during chemotaxis
CS344_RS13035	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS344_RS13045	COG1338	Plays a role in the flagellum-specific transport system
CS344_RS13060	COG0840	transmembrane signaling receptor activity
CS344_RS13065	COG0840	transmembrane signaling receptor activity
CS344_RS13075	COG0840	transmembrane signaling receptor activity
CS344_RS13080	COG0840	transmembrane signaling receptor activity
CS344_RS13090	COG1256	bacterial-type flagellum assembly
CS344_RS13105	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CS344_RS13120	COG1749	Flagellar hook protein flgE
CS344_RS13130	COG1558	bacterial-type flagellum-dependent cell motility
CS344_RS13135	COG1815	bacterial-type flagellum-dependent cell motility
CS344_RS13170	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CS344_RS13175	COG0745	RESPONSE REGULATOR receiver
CS344_RS13180	COG2201	protein-glutamate methylesterase activity
CS344_RS13185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CS344_RS13190	COG0840	transmembrane signaling receptor activity
CS344_RS13200	COG0643	Histidine kinase
CS344_RS13200	COG2198	Histidine kinase
CS344_RS13205	COG0745	RESPONSE REGULATOR receiver
CS344_RS13235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CS344_RS13240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS344_RS13245	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS344_RS13250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CS344_RS13260	COG4566	intracellular signal transduction
CS344_RS13265	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS344_RS13270	COG0339	signal peptide processing
CS344_RS13275	COG1999	signal sequence binding
CS344_RS13295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS13305	COG1187	pseudouridine synthase activity
CS344_RS13310	COG3161	chorismate lyase activity
CS344_RS13315	COG2814	Major facilitator Superfamily
CS344_RS13325	COG1280	lysine exporter protein (LysE YggA)
CS344_RS13330	COG4172	Belongs to the ABC transporter superfamily
CS344_RS13335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS13340	COG0601	transmembrane transport
CS344_RS13345	COG0747	negative chemotaxis
CS344_RS13390	COG0668	transmembrane transport
CS344_RS13395	COG0165	Argininosuccinate lyase
CS344_RS13405	COG0789	Transcriptional regulator
CS344_RS13415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS13420	COG0765	amino acid transport
CS344_RS13425	COG1126	abc transporter atp-binding protein
CS344_RS13435	COG2346	COG2346, Truncated hemoglobins
CS344_RS13495	COG1335	isochorismatase
CS344_RS13500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS13520	COG2837	iron assimilation
CS344_RS13550	COG4691	Plasmid stability protein
CS344_RS13585	COG0583	DNA-binding transcription factor activity
CS344_RS13590	COG2814	Major facilitator Superfamily
CS344_RS13600	COG0501	Belongs to the peptidase M48B family
CS344_RS13610	COG0583	DNA-binding transcription factor activity
CS344_RS13620	COG2188	Transcriptional regulator
CS344_RS13635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS344_RS13645	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS13650	COG0129	dihydroxy-acid dehydratase activity
CS344_RS13665	COG0129	dihydroxy-acid dehydratase activity
CS344_RS13675	COG3622	Belongs to the hyi family
CS344_RS13680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS344_RS13685	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS13700	COG0583	DNA-binding transcription factor activity
CS344_RS13705	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS13710	COG3246	L-lysine catabolic process to acetate
CS344_RS13725	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CS344_RS13730	COG0534	Mate efflux family protein
CS344_RS13745	COG0697	spore germination
CS344_RS13760	COG0625	glutathione transferase activity
CS344_RS13780	COG1280	lysine exporter protein (LysE YggA)
CS344_RS13785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS344_RS13820	COG2207	Transcriptional regulator
CS344_RS13860	COG1132	(ABC) transporter
CS344_RS13885	COG0659	secondary active sulfate transmembrane transporter activity
CS344_RS13915	COG2169	Transcriptional regulator
CS344_RS13920	COG5507	3-demethylubiquinone-9 3-methyltransferase
CS344_RS13925	COG0384	phenazine biosynthesis protein PhzF
CS344_RS13930	COG0583	DNA-binding transcription factor activity
CS344_RS13935	COG2733	membrane
CS344_RS13950	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS13955	COG3284	Transcriptional regulator
CS344_RS13960	COG0656	L-ascorbic acid biosynthetic process
CS344_RS13980	COG1131	(ABC) transporter
CS344_RS13985	COG0842	Transport permease protein
CS344_RS13990	COG0842	Transport permease protein
CS344_RS14005	COG1802	Transcriptional regulator
CS344_RS14025	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS14030	COG2188	Transcriptional regulator
CS344_RS14055	COG0789	Transcriptional regulator
CS344_RS14070	COG1609	Transcriptional regulator
CS344_RS14075	COG4172	Belongs to the ABC transporter superfamily
CS344_RS14080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS14085	COG0601	transmembrane transport
CS344_RS14090	COG0747	negative chemotaxis
CS344_RS14105	COG1280	lysine exporter protein (LysE YggA)
CS344_RS14125	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CS344_RS14150	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS14155	COG2079	MmgE PrpD family protein
CS344_RS14180	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS14190	COG3618	amidohydrolase
CS344_RS14205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CS344_RS14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS14235	COG1116	anion transmembrane transporter activity
CS344_RS14245	COG1228	amidohydrolase
CS344_RS14250	COG1414	Transcriptional regulator
CS344_RS14260	COG0477	Major facilitator Superfamily
CS344_RS14280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS344_RS14280	COG0519	Catalyzes the synthesis of GMP from XMP
CS344_RS14300	COG2197	response regulator
CS344_RS14315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS344_RS14330	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS14350	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS344_RS14350	COG3210	domain, Protein
CS344_RS14350	COG3064	Membrane
CS344_RS14355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CS344_RS14355	COG0047	phosphoribosylformylglycinamidine synthase activity
CS344_RS14360	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS14365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS14365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS14370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS14380	COG0613	PHP domain protein
CS344_RS14390	COG0658	competence protein
CS344_RS14390	COG2333	competence protein COMEC
CS344_RS14400	COG0084	hydrolase, TatD family'
CS344_RS14405	COG1136	(ABC) transporter
CS344_RS14420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CS344_RS14430	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS14435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CS344_RS14450	COG1022	Amp-dependent synthetase and ligase
CS344_RS14480	COG1024	Enoyl-CoA hydratase
CS344_RS14495	COG0633	Ferredoxin
CS344_RS14500	COG0443	Heat shock 70 kDa protein
CS344_RS14505	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CS344_RS14510	COG0316	Belongs to the HesB IscA family
CS344_RS14515	COG0822	iron-sulfur transferase activity
CS344_RS14520	COG1104	cysteine desulfurase activity
CS344_RS14530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS344_RS14535	COG0556	nucleotide-excision repair
CS344_RS14545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS344_RS14550	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS14560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS344_RS14575	COG1960	acyl-CoA dehydrogenase activity
CS344_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS14585	COG0183	Belongs to the thiolase family
CS344_RS14595	COG1024	Enoyl-CoA hydratase
CS344_RS14610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS14615	COG0583	DNA-binding transcription factor activity
CS344_RS14620	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS344_RS14630	COG0740	serine-type endopeptidase activity
CS344_RS14635	COG0544	peptidyl-prolyl cis-trans isomerase activity
CS344_RS14645	COG1278	Cold shock
CS344_RS14655	COG1278	Cold shock
CS344_RS14685	COG0436	Aminotransferase
CS344_RS14690	COG2171	N-acyltransferase activity
CS344_RS14695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS344_RS14700	COG2890	protein-(glutamine-N5) methyltransferase activity
CS344_RS14705	COG0488	(ABC) transporter
CS344_RS14710	COG4771	TonB-dependent receptor
CS344_RS14715	COG0210	DNA helicase
CS344_RS14730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS344_RS14730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS344_RS14735	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CS344_RS14740	COG0196	riboflavin kinase activity
CS344_RS14745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CS344_RS14750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CS344_RS14755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CS344_RS14765	COG1522	sequence-specific DNA binding
CS344_RS14775	COG0586	Pfam SNARE associated Golgi protein
CS344_RS14790	COG1126	abc transporter atp-binding protein
CS344_RS14795	COG0765	amino acid transport
CS344_RS14800	COG0765	amino acid transport
CS344_RS14805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS14815	COG2423	ornithine cyclodeaminase activity
CS344_RS14820	COG1764	response to oxidative stress
CS344_RS14830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS344_RS14835	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS344_RS14850	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CS344_RS14855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CS344_RS14860	COG2197	response regulator
CS344_RS14870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS344_RS14915	COG0135	phosphoribosylanthranilate isomerase activity
CS344_RS14930	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS14945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS344_RS14970	COG1122	ATPase activity
CS344_RS15000	COG0437	4 iron, 4 sulfur cluster binding
CS344_RS15005	COG3383	formate dehydrogenase (NAD+) activity
CS344_RS15005	COG0243	molybdopterin cofactor binding
CS344_RS15035	COG0489	protein tyrosine kinase activity
CS344_RS15040	COG0746	molybdenum cofactor guanylyltransferase activity
CS344_RS15045	COG0303	'Molybdopterin
CS344_RS15050	COG1763	Mo-molybdopterin cofactor biosynthetic process
CS344_RS15060	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CS344_RS15065	COG5001	Diguanylate cyclase
CS344_RS15065	COG3300	MHYT domain
CS344_RS15070	COG2205	protein histidine kinase activity
CS344_RS15075	COG0745	RESPONSE REGULATOR receiver
CS344_RS15090	COG1295	ribonuclease BN
CS344_RS15100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS344_RS15135	COG4964	Belongs to the GSP D family
CS344_RS15200	COG0861	Integral membrane protein TerC family
CS344_RS15205	COG0861	Integral membrane protein TerC family
CS344_RS15210	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS344_RS15215	COG0045	succinate-CoA ligase (ADP-forming) activity
CS344_RS15235	COG2137	regulation of response to DNA damage stimulus
CS344_RS15240	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CS344_RS15260	COG1024	Enoyl-CoA hydratase
CS344_RS15260	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS15265	COG3842	ATPase activity
CS344_RS15280	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS15300	COG0583	DNA-binding transcription factor activity
CS344_RS15305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS15315	COG2974	May be involved in recombination
CS344_RS15320	COG0540	Belongs to the ATCase OTCase family
CS344_RS15360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS15375	COG1522	sequence-specific DNA binding
CS344_RS15385	COG2367	Beta-lactamase
CS344_RS15400	COG0500	methyltransferase
CS344_RS15435	COG0072	phenylalanine-tRNA ligase activity
CS344_RS15435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS344_RS15440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CS344_RS15445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CS344_RS15450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CS344_RS15475	COG0004	ammonium transporteR
CS344_RS15485	COG1309	transcriptional regulator
CS344_RS15490	COG2271	Major facilitator Superfamily
CS344_RS15520	COG0506	proline dehydrogenase activity
CS344_RS15520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS344_RS15520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS344_RS15530	COG3008	intermembrane lipid transfer
CS344_RS15530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS344_RS15535	COG2995	paraquat-inducible protein a
CS344_RS15540	COG0542	response to heat
CS344_RS15545	COG4953	penicillin-binding protein 1C
CS344_RS15560	COG1278	Cold shock
CS344_RS15570	COG0183	Belongs to the thiolase family
CS344_RS15575	COG0038	chloride channel
CS344_RS15580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS344_RS15590	COG0811	peptide transport
CS344_RS15595	COG0848	biopolymer transport protein
CS344_RS15605	COG2835	tetraacyldisaccharide 4'-kinase activity
CS344_RS15615	COG0563	adenylate kinase activity
CS344_RS15625	COG0728	peptidoglycan biosynthetic process
CS344_RS15635	COG0268	Binds directly to 16S ribosomal RNA
CS344_RS15655	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS344_RS15660	COG2186	Transcriptional regulator
CS344_RS15680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS344_RS15690	COG0583	DNA-binding transcription factor activity
CS344_RS15700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS344_RS15705	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CS344_RS15715	COG3158	transport of potassium into the cell
CS344_RS15720	COG0642	Histidine kinase
CS344_RS15750	COG0776	regulation of translation
CS344_RS15755	COG3128	pkhd-type hydroxylase
CS344_RS15765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS344_RS15770	COG0557	exoribonuclease II activity
CS344_RS15795	COG0679	Auxin Efflux Carrier
CS344_RS15800	COG2391	methyltransferase activity
CS344_RS15805	COG0069	glutamate synthase activity
CS344_RS15810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS344_RS15820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CS344_RS15825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS344_RS15860	COG3706	GGDEF domain
CS344_RS15890	COG3909	cytochrome
CS344_RS15895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CS344_RS15900	COG0625	glutathione transferase activity
CS344_RS15905	COG0730	response to heat
CS344_RS15910	COG0482	sulfurtransferase activity
CS344_RS15915	COG0583	DNA-binding transcription factor activity
CS344_RS15955	COG2819	hydrolase of the alpha beta superfamily
CS344_RS15960	COG0247	lactate metabolic process
CS344_RS15965	COG0277	FAD linked oxidase domain protein
CS344_RS15970	COG0277	FAD linked oxidase domain protein
CS344_RS15975	COG0277	FAD linked oxidase domain protein
CS344_RS15980	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS344_RS15980	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS344_RS15980	COG3064	Membrane
CS344_RS15980	COG3064	Membrane
CS344_RS15980	COG3210	domain, Protein
CS344_RS15980	COG3210	domain, Protein
CS344_RS15985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS344_RS15990	COG0312	modulator of DNA gyrase
CS344_RS16010	COG0308	aminopeptidase N
CS344_RS16015	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CS344_RS16035	COG0436	Aminotransferase
CS344_RS16040	COG3737	Protein of unknown function (DUF498/DUF598)
CS344_RS16045	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS344_RS16050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CS344_RS16055	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS344_RS16065	COG0305	Participates in initiation and elongation during chromosome replication
CS344_RS16080	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CS344_RS16085	COG2965	DNA replication, synthesis of RNA primer
CS344_RS16090	COG0360	Binds together with S18 to 16S ribosomal RNA
CS344_RS16095	COG1469	GTP cyclohydrolase I activity
CS344_RS16105	COG0142	geranyltranstransferase activity
CS344_RS16110	COG1722	exodeoxyribonuclease VII activity
CS344_RS16120	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS16155	COG1840	ABC-type Fe3 transport system, periplasmic component
CS344_RS16160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS344_RS16165	COG1178	ABC-type Fe3 transport system permease component
CS344_RS16170	COG3842	ATPase activity
CS344_RS16175	COG0583	DNA-binding transcription factor activity
CS344_RS16195	COG0501	Belongs to the peptidase M48B family
CS344_RS16205	COG0697	spore germination
CS344_RS16215	COG1846	Transcriptional regulator
CS344_RS16225	COG1566	PFAM secretion protein HlyD family protein
CS344_RS16230	COG2814	Major facilitator Superfamily
CS344_RS16235	COG0473	3-isopropylmalate dehydrogenase activity
CS344_RS16245	COG0747	negative chemotaxis
CS344_RS16255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS16260	COG4172	Belongs to the ABC transporter superfamily
CS344_RS16265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS344_RS16290	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS16300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS344_RS16305	COG0433	COG0433 Predicted ATPase
CS344_RS16315	COG0151	Belongs to the GarS family
CS344_RS16325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CS344_RS16330	COG0799	negative regulation of ribosome biogenesis
CS344_RS16335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CS344_RS16345	COG3468	outer membrane autotransporter barrel domain protein
CS344_RS16375	COG1530	ribonuclease E activity
CS344_RS16380	COG0077	Prephenate dehydratase
CS344_RS16395	COG1132	(ABC) transporter
CS344_RS16400	COG0859	PFAM glycosyl transferase family 9
CS344_RS16425	COG2194	sulfuric ester hydrolase activity
CS344_RS16430	COG0438	transferase activity, transferring glycosyl groups
CS344_RS16435	COG0463	Glycosyl transferase, family 2
CS344_RS16440	COG0726	polysaccharide deacetylase
CS344_RS16445	COG0438	transferase activity, transferring glycosyl groups
CS344_RS16460	COG1643	Atp-dependent helicase
CS344_RS16465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS344_RS16465	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CS344_RS16470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CS344_RS16480	COG0704	Plays a role in the regulation of phosphate uptake
CS344_RS16490	COG1960	acyl-CoA dehydrogenase activity
CS344_RS16515	COG1177	transmembrane transport
CS344_RS16520	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS344_RS16525	COG3842	ATPase activity
CS344_RS16530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CS344_RS16545	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CS344_RS16560	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS16560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS16565	COG3539	Fimbrial protein
CS344_RS16570	COG3539	Fimbrial protein
CS344_RS16575	COG3539	Fimbrial protein
CS344_RS16580	COG3539	Fimbrial protein
CS344_RS16590	COG2050	protein possibly involved in aromatic compounds catabolism
CS344_RS16595	COG1024	Enoyl-CoA hydratase
CS344_RS16600	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS16605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS344_RS16610	COG2151	metal-sulfur cluster biosynthetic enzyme
CS344_RS16615	COG3396	Phenylacetate-CoA oxygenase
CS344_RS16620	COG3460	Phenylacetate-CoA oxygenase
CS344_RS16625	COG3396	Phenylacetate-CoA oxygenase
CS344_RS16630	COG3327	negative regulation of DNA-templated transcription, initiation
CS344_RS16640	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CS344_RS16645	COG0501	Belongs to the peptidase M48B family
CS344_RS16650	COG1162	GTPase activity
CS344_RS16655	COG0667	Aldo Keto reductase
CS344_RS16665	COG0335	large ribosomal subunit rRNA binding
CS344_RS16695	COG0175	sulfate reduction
CS344_RS16700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS344_RS16705	COG4208	sulfate ABC transporter
CS344_RS16720	COG0450	alkyl hydroperoxide reductase
CS344_RS16725	COG1960	acyl-CoA dehydrogenase activity
CS344_RS16740	COG0123	including yeast histone deacetylase and acetoin utilization protein
CS344_RS16745	COG2951	lytic endotransglycosylase activity
CS344_RS16755	COG1555	photosystem II stabilization
CS344_RS16755	COG1596	polysaccharide export
CS344_RS16765	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CS344_RS16770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CS344_RS16790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CS344_RS16795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CS344_RS16800	COG0287	Prephenate dehydrogenase
CS344_RS16825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CS344_RS16835	COG2814	Major facilitator Superfamily
CS344_RS16845	COG2135	peptidase activity
CS344_RS16915	COG1196	nuclear chromosome segregation
CS344_RS17145	COG0582	viral genome integration into host DNA
CS344_RS17150	COG0583	DNA-binding transcription factor activity
CS344_RS17190	COG0583	DNA-binding transcription factor activity
CS344_RS17205	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS344_RS17230	COG1053	succinate dehydrogenase
CS344_RS17235	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS17240	COG2079	MmgE PrpD family protein
CS344_RS17250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS17265	COG0583	DNA-binding transcription factor activity
CS344_RS17275	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CS344_RS17275	COG0028	Belongs to the TPP enzyme family
CS344_RS17280	COG0436	Aminotransferase
CS344_RS17300	COG0778	Nitroreductase
CS344_RS17305	COG2814	Major facilitator Superfamily
CS344_RS17310	COG3706	GGDEF domain
CS344_RS17315	COG0589	response to stress
CS344_RS17325	COG2951	lytic endotransglycosylase activity
CS344_RS17330	COG2833	Protein of unknown function (DUF455)
CS344_RS17345	COG1132	(ABC) transporter
CS344_RS17350	COG0189	ligase activity
CS344_RS17350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS344_RS17355	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS344_RS17355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS344_RS17360	COG3237	CsbD-like
CS344_RS17370	COG2823	Periplasmic or secreted lipoprotein
CS344_RS17385	COG0672	)-iron permease
CS344_RS17400	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CS344_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS17410	COG3243	poly(R)-hydroxyalkanoic acid synthase
CS344_RS17420	COG0564	pseudouridine synthase activity
CS344_RS17430	COG1199	ATP-dependent helicase activity
CS344_RS17435	COG2183	response to ionizing radiation
CS344_RS17460	COG4774	siderophore transport
CS344_RS17465	COG3712	iron ion homeostasis
CS344_RS17470	COG1595	DNA-templated transcription, initiation
CS344_RS17475	COG2175	clavaminate synthase activity
CS344_RS17485	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS17490	COG0583	DNA-binding transcription factor activity
CS344_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS17500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CS344_RS17505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS344_RS17510	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS344_RS17515	COG0567	Dehydrogenase, E1 component
CS344_RS17520	COG1297	OPT oligopeptide transporter protein
CS344_RS17525	COG1522	sequence-specific DNA binding
CS344_RS17535	COG0281	malic enzyme
CS344_RS17535	COG0280	phosphate acetyltransferase
CS344_RS17540	COG3539	Fimbrial protein
CS344_RS17555	COG0372	Belongs to the citrate synthase family
CS344_RS17560	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CS344_RS17565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CS344_RS17570	COG1053	succinate dehydrogenase
CS344_RS17575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CS344_RS17580	COG2009	succinate dehydrogenase
CS344_RS17585	COG2188	Transcriptional regulator
CS344_RS17590	COG0039	L-malate dehydrogenase activity
CS344_RS17610	COG2828	Protein conserved in bacteria
CS344_RS17620	COG1981	membrane
CS344_RS17645	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS344_RS17655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CS344_RS17685	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CS344_RS17690	COG0148	phosphopyruvate hydratase activity
CS344_RS17700	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CS344_RS17705	COG0504	CTP synthase activity
CS344_RS17725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS17735	COG0747	negative chemotaxis
CS344_RS17740	COG4172	Belongs to the ABC transporter superfamily
CS344_RS17745	COG1446	asparaginase
CS344_RS17775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CS344_RS17790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CS344_RS17795	COG0697	spore germination
CS344_RS17800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS344_RS17810	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CS344_RS17815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS344_RS17820	COG0791	NLP P60 protein
CS344_RS17830	COG0583	DNA-binding transcription factor activity
CS344_RS17845	COG0583	DNA-binding transcription factor activity
CS344_RS17870	COG0670	Belongs to the BI1 family
CS344_RS17885	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CS344_RS17895	COG1381	Involved in DNA repair and RecF pathway recombination
CS344_RS17900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CS344_RS17905	COG0571	ribonuclease III activity
CS344_RS17910	COG0681	Belongs to the peptidase S26 family
CS344_RS17920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS344_RS17945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS344_RS17950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CS344_RS17965	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS344_RS17975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CS344_RS17980	COG1399	metal-binding, possibly nucleic acid-binding protein
CS344_RS17995	COG3023	N-Acetylmuramoyl-L-alanine amidase
CS344_RS18005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CS344_RS18010	COG0546	phosphoglycolate phosphatase activity
CS344_RS18020	COG1530	ribonuclease E activity
CS344_RS18030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CS344_RS18035	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CS344_RS18040	COG0159	tryptophan synthase activity
CS344_RS18055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS344_RS18060	COG3228	Belongs to the MtfA family
CS344_RS18070	COG0251	oxidation-reduction process
CS344_RS18075	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CS344_RS18080	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CS344_RS18095	COG2878	Part of a membrane complex involved in electron transport
CS344_RS18100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CS344_RS18135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS344_RS18160	COG1268	BioY protein
CS344_RS18165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CS344_RS18170	COG1122	ATPase activity
CS344_RS18175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS344_RS18185	COG0271	Belongs to the BolA IbaG family
CS344_RS18190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS344_RS18195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CS344_RS18205	COG1196	nuclear chromosome segregation
CS344_RS18210	COG0477	Major facilitator Superfamily
CS344_RS18215	COG1573	uracil-dna glycosylase
CS344_RS18220	COG1214	PFAM Peptidase M22, glycoprotease
CS344_RS18235	COG0450	alkyl hydroperoxide reductase
CS344_RS18240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS18250	COG2223	nitrite transmembrane transporter activity
CS344_RS18255	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CS344_RS18260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CS344_RS18265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CS344_RS18270	COG0560	Phosphoserine phosphatase
CS344_RS18275	COG0583	DNA-binding transcription factor activity
CS344_RS18280	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS18285	COG0028	Belongs to the TPP enzyme family
CS344_RS18300	COG4774	siderophore transport
CS344_RS18305	COG4774	siderophore transport
CS344_RS18315	COG1007	ATP synthesis coupled electron transport
CS344_RS18330	COG0713	ATP synthesis coupled electron transport
CS344_RS18340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS344_RS18345	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CS344_RS18350	COG1034	ATP synthesis coupled electron transport
CS344_RS18360	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CS344_RS18370	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS344_RS18375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS344_RS18380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS344_RS18385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS344_RS18405	COG0671	phosphoesterase, PA-phosphatase related
CS344_RS18415	COG1597	lipid kinase activity
CS344_RS18420	COG0583	DNA-binding transcription factor activity
CS344_RS18425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS344_RS18430	COG1733	regulation of RNA biosynthetic process
CS344_RS18435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS18440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS344_RS18455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CS344_RS18475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS18495	COG3608	succinylglutamate desuccinylase aspartoacylase
CS344_RS18500	COG0626	cystathionine gamma-synthase activity
CS344_RS18505	COG0583	DNA-binding transcription factor activity
CS344_RS18515	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS18520	COG0165	Argininosuccinate lyase
CS344_RS18535	COG3799	methylaspartate ammonia-lyase activity
CS344_RS18545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS344_RS18555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS344_RS18560	COG0149	triose-phosphate isomerase activity
CS344_RS18580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS344_RS18590	COG1185	polyribonucleotide nucleotidyltransferase activity
CS344_RS18595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CS344_RS18610	COG1183	phosphatidylcholine synthase activity
CS344_RS18620	COG0440	acetolactate synthase activity
CS344_RS18625	COG0028	Belongs to the TPP enzyme family
CS344_RS18630	COG1289	transmembrane transporter activity
CS344_RS18640	COG3022	response to hydroperoxide
CS344_RS18645	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS18660	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CS344_RS18690	COG2814	Major facilitator Superfamily
CS344_RS18710	COG3706	GGDEF domain
CS344_RS18740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CS344_RS18745	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CS344_RS18750	COG1674	ftsk spoiiie
CS344_RS18755	COG0492	ferredoxin-NADP+ reductase activity
CS344_RS18760	COG1193	negative regulation of DNA recombination
CS344_RS18770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CS344_RS18785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CS344_RS18790	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CS344_RS18795	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CS344_RS18800	COG2205	protein histidine kinase activity
CS344_RS18805	COG0745	RESPONSE REGULATOR receiver
CS344_RS18840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS344_RS18860	COG0612	Peptidase, M16
CS344_RS18865	COG0484	heat shock protein binding
CS344_RS18870	COG0443	Heat shock 70 kDa protein
CS344_RS18880	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CS344_RS18890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CS344_RS18895	COG1420	regulation of RNA biosynthetic process
CS344_RS18905	COG0497	DNA recombination
CS344_RS18910	COG0735	belongs to the Fur family
CS344_RS18915	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS344_RS18925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CS344_RS18945	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS18960	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS344_RS18960	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS344_RS18965	COG4311	Sarcosine oxidase, delta subunit
CS344_RS18970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS18980	COG0583	DNA-binding transcription factor activity
CS344_RS18990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS344_RS19000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS19005	COG2030	dehydratase
CS344_RS19015	COG1024	Enoyl-CoA hydratase
CS344_RS19040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS344_RS19050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS344_RS19050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS344_RS19065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS344_RS19070	COG0730	response to heat
CS344_RS19080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS19090	COG0405	Gamma-glutamyltransferase
CS344_RS19105	COG1280	lysine exporter protein (LysE YggA)
CS344_RS19135	COG0583	DNA-binding transcription factor activity
CS344_RS19145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CS344_RS19150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CS344_RS19155	COG0167	dihydroorotate dehydrogenase activity
CS344_RS19175	COG1414	Transcriptional regulator
CS344_RS19180	COG1058	Belongs to the CinA family
CS344_RS19180	COG1546	Belongs to the CinA family
CS344_RS19195	COG0513	Belongs to the DEAD box helicase family
CS344_RS19230	COG0429	hydrolase of the alpha beta-hydrolase fold
CS344_RS19235	COG4783	chaperone-mediated protein folding
CS344_RS19250	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS344_RS19265	COG0006	proline dipeptidase activity
CS344_RS19275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS344_RS19295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CS344_RS19300	COG0632	four-way junction helicase activity
CS344_RS19315	COG2255	four-way junction helicase activity
CS344_RS19320	COG0514	ATP-dependent DNA helicase (RecQ)
CS344_RS19345	COG1271	oxidase subunit
CS344_RS19350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS344_RS19355	COG0850	regulation of cytokinetic process
CS344_RS19360	COG2894	cell division
CS344_RS19365	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CS344_RS19380	COG0488	(ABC) transporter
CS344_RS19405	COG4608	Belongs to the ABC transporter superfamily
CS344_RS19410	COG0444	Belongs to the ABC transporter superfamily
CS344_RS19415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS19420	COG0601	transmembrane transport
CS344_RS19430	COG1215	transferase activity, transferring glycosyl groups
CS344_RS19445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CS344_RS19455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS344_RS19470	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS19475	COG2188	Transcriptional regulator
CS344_RS19480	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CS344_RS19485	COG2814	Major facilitator Superfamily
CS344_RS19495	COG0259	pyridoxamine-phosphate oxidase activity
CS344_RS19500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS344_RS19515	COG0583	DNA-binding transcription factor activity
CS344_RS19520	COG1960	acyl-CoA dehydrogenase activity
CS344_RS19530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS19535	COG0405	Gamma-glutamyltransferase
CS344_RS19545	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS19560	COG0802	atpase or kinase
CS344_RS19565	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS344_RS19570	COG0586	Pfam SNARE associated Golgi protein
CS344_RS19575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CS344_RS19580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CS344_RS19585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CS344_RS19600	COG0617	tRNA 3'-terminal CCA addition
CS344_RS19625	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS19630	COG2188	Transcriptional regulator
CS344_RS19640	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS344_RS19645	COG1234	tRNA 3'-trailer cleavage
CS344_RS19650	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS19660	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS19665	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS19670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS344_RS19675	COG2301	Belongs to the HpcH HpaI aldolase family
CS344_RS19680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS19685	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CS344_RS19695	COG1024	Enoyl-CoA hydratase
CS344_RS19705	COG2188	Transcriptional regulator
CS344_RS19710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS344_RS19715	COG0066	3-isopropylmalate dehydratase activity
CS344_RS19730	COG0752	glycyl-tRNA synthetase alpha subunit
CS344_RS19735	COG0751	glycine-tRNA ligase activity
CS344_RS19740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS344_RS19745	COG0204	Acyl-transferase
CS344_RS19760	COG0242	peptide deformylase activity
CS344_RS19765	COG1960	acyl-CoA dehydrogenase activity
CS344_RS19770	COG0700	Nucleoside recognition
CS344_RS19775	COG0469	pyruvate kinase activity
CS344_RS19780	COG1929	Belongs to the glycerate kinase type-1 family
CS344_RS19785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CS344_RS19790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS344_RS19805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CS344_RS19815	COG2154	pterin-4-alpha-carbinolamine dehydratase
CS344_RS19835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS344_RS19840	COG0154	amidase activity
CS344_RS19850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS19855	COG0601	transmembrane transport
CS344_RS19860	COG0747	negative chemotaxis
CS344_RS19875	COG0019	diaminopimelate decarboxylase activity
CS344_RS19890	COG3712	iron ion homeostasis
CS344_RS19895	COG4774	siderophore transport
CS344_RS19900	COG2353	YceI-like domain
CS344_RS19905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS344_RS19920	COG0583	DNA-binding transcription factor activity
CS344_RS19940	COG3384	dioxygenase
CS344_RS19945	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS344_RS19980	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS19985	COG1309	transcriptional regulator
CS344_RS19990	COG2982	Protein involved in outer membrane biogenesis
CS344_RS19995	COG2818	Glycosylase
CS344_RS20015	COG1653	transport
CS344_RS20020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS344_RS20025	COG3842	ATPase activity
CS344_RS20030	COG0395	ABC-type sugar transport system, permease component
CS344_RS20035	COG1175	transmembrane transport
CS344_RS20050	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS20055	COG2186	Transcriptional regulator
CS344_RS20075	COG1454	alcohol dehydrogenase
CS344_RS20300	COG0629	single-stranded DNA binding
CS344_RS20355	COG0582	viral genome integration into host DNA
CS344_RS20370	COG2011	ABC-type metal ion transport system permease component
CS344_RS20375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS344_RS20380	COG1501	Belongs to the glycosyl hydrolase 31 family
CS344_RS20385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS20385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CS344_RS20395	COG0318	PFAM AMP-dependent synthetase and ligase
CS344_RS20400	COG1473	amidohydrolase
CS344_RS20410	COG2855	membrane
CS344_RS20420	COG2239	Acts as a magnesium transporter
CS344_RS20435	COG1522	sequence-specific DNA binding
CS344_RS20440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS20445	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS20455	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS20465	COG0653	protein targeting
CS344_RS20470	COG0739	heme binding
CS344_RS20480	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CS344_RS20485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CS344_RS20495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CS344_RS20500	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS344_RS20510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CS344_RS20520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CS344_RS20525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS344_RS20530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS344_RS20540	COG3116	cell division
CS344_RS20545	COG0275	rRNA processing
CS344_RS20550	COG2001	Belongs to the MraZ family
CS344_RS20560	COG0488	(ABC) transporter
CS344_RS20565	COG0418	dihydroorotase activity
CS344_RS20570	COG1473	amidohydrolase
CS344_RS20620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS344_RS20625	COG4654	Cytochrome c, class I
CS344_RS20630	COG0129	dihydroxy-acid dehydratase activity
CS344_RS20635	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CS344_RS20675	COG2084	Dehydrogenase
CS344_RS20680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CS344_RS20710	COG0494	nUDIX hydrolase
CS344_RS20715	COG0442	prolyl-tRNA aminoacylation
CS344_RS20720	COG0824	Thioesterase
CS344_RS20725	COG0811	peptide transport
CS344_RS20730	COG0848	biopolymer transport protein
CS344_RS20740	COG0823	Involved in the tonB-independent uptake of proteins
CS344_RS20755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS344_RS20760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CS344_RS20765	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS20780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS344_RS20805	COG0183	Belongs to the thiolase family
CS344_RS20815	COG1960	acyl-CoA dehydrogenase activity
CS344_RS20820	COG0583	DNA-binding transcription factor activity
CS344_RS20825	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS20830	COG1024	Enoyl-CoA hydratase
CS344_RS20835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS20840	COG1253	flavin adenine dinucleotide binding
CS344_RS20845	COG1285	pathogenesis
CS344_RS20850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS344_RS20865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS344_RS20870	COG0697	spore germination
CS344_RS20900	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CS344_RS20905	COG0463	Glycosyl transferase, family 2
CS344_RS20915	COG0786	glutamate:sodium symporter activity
CS344_RS20925	COG2031	fatty acid transporter
CS344_RS20940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS344_RS20945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS344_RS20950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS344_RS20955	COG0328	RNA-DNA hybrid ribonuclease activity
CS344_RS20960	COG2226	methyltransferase
CS344_RS20965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS344_RS20970	COG0741	lytic transglycosylase activity
CS344_RS20970	COG1388	LysM domain
CS344_RS20985	COG2979	Protein of unknown function (DUF533)
CS344_RS21065	COG2816	NAD+ diphosphatase activity
CS344_RS21070	COG1309	transcriptional regulator
CS344_RS21075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS21090	COG1024	Enoyl-CoA hydratase
CS344_RS21105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS21120	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS21135	COG3119	arylsulfatase activity
CS344_RS21160	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CS344_RS21175	COG0804	urea catabolic process
CS344_RS21180	COG0832	Belongs to the urease beta subunit family
CS344_RS21190	COG0831	urea catabolic process
CS344_RS21195	COG0829	nickel cation binding
CS344_RS21205	COG0633	Ferredoxin
CS344_RS21220	COG2188	Transcriptional regulator
CS344_RS21245	COG2719	SpoVR family
CS344_RS21250	COG2718	Belongs to the UPF0229 family
CS344_RS21255	COG2766	serine protein kinase
CS344_RS21260	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS344_RS21260	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS344_RS21270	COG4977	sequence-specific DNA binding
CS344_RS21275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CS344_RS21280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CS344_RS21290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CS344_RS21305	COG0316	Belongs to the HesB IscA family
CS344_RS21320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS344_RS21325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CS344_RS21330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS344_RS21335	COG0312	modulator of DNA gyrase
CS344_RS21355	COG1116	anion transmembrane transporter activity
CS344_RS21360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS21365	COG1335	isochorismatase
CS344_RS21370	COG0346	lactoylglutathione lyase activity
CS344_RS21375	COG0513	Belongs to the DEAD box helicase family
CS344_RS21380	COG3069	C4-dicarboxylate transmembrane transporter activity
CS344_RS21385	COG1802	Transcriptional regulator
CS344_RS21390	COG0045	succinate-CoA ligase (ADP-forming) activity
CS344_RS21390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS344_RS21390	COG1042	CoA-binding domain protein
CS344_RS21395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS344_RS21410	COG1522	sequence-specific DNA binding
CS344_RS21440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS344_RS21445	COG1696	Membrane protein involved in D-alanine export
CS344_RS21470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS344_RS21480	COG2264	protein methyltransferase activity
CS344_RS21485	COG0439	Biotin carboxylase
CS344_RS21490	COG0511	ligase activity, forming carbon-carbon bonds
CS344_RS21495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS344_RS21500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS344_RS21505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS344_RS21510	COG3150	esterase
CS344_RS21515	COG0557	exoribonuclease II activity
CS344_RS21525	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CS344_RS21530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CS344_RS21555	COG0540	Belongs to the ATCase OTCase family
CS344_RS21565	COG1678	Uncharacterized ACR, COG1678
CS344_RS21580	COG0352	thiamine-phosphate diphosphorylase activity
CS344_RS21585	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CS344_RS21610	COG1960	acyl-CoA dehydrogenase activity
CS344_RS21615	COG1024	Enoyl-CoA hydratase
CS344_RS21620	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS21680	COG0494	nUDIX hydrolase
CS344_RS21705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CS344_RS21715	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CS344_RS21730	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CS344_RS21735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CS344_RS21745	COG0477	Major facilitator Superfamily
CS344_RS21765	COG1126	abc transporter atp-binding protein
CS344_RS21770	COG0765	amino acid transport
CS344_RS21775	COG4597	amino acid ABC transporter
CS344_RS21780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS21785	COG2884	Cell division ATP-binding protein ftsE
CS344_RS21790	COG2177	Part of the ABC transporter FtsEX involved in
CS344_RS21795	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CS344_RS21805	COG1194	a g-specific adenine glycosylase
CS344_RS21815	COG2226	methyltransferase
CS344_RS21825	COG4206	TonB-dependent receptor
CS344_RS21830	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS344_RS21835	COG2022	thiamine diphosphate biosynthetic process
CS344_RS21840	COG0351	phosphomethylpyrimidine kinase
CS344_RS21845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CS344_RS21855	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CS344_RS21865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CS344_RS21880	COG2226	methyltransferase
CS344_RS21885	COG0745	RESPONSE REGULATOR receiver
CS344_RS21890	COG5002	protein histidine kinase activity
CS344_RS21900	COG5002	protein histidine kinase activity
CS344_RS21910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS344_RS21915	COG0583	DNA-binding transcription factor activity
CS344_RS21925	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS344_RS21930	COG1984	allophanate hydrolase subunit 2
CS344_RS21945	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS21955	COG1024	Enoyl-CoA hydratase
CS344_RS21960	COG0657	acetylesterase activity
CS344_RS21970	COG1802	Transcriptional regulator
CS344_RS21980	COG1238	metal cluster binding
CS344_RS21985	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS344_RS21990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS344_RS22010	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CS344_RS22015	COG4988	ABC transporter
CS344_RS22025	COG1294	oxidase, subunit
CS344_RS22040	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CS344_RS22050	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CS344_RS22065	COG1137	ATPase activity
CS344_RS22070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CS344_RS22085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS344_RS22085	COG2010	Cytochrome c
CS344_RS22095	COG1660	Displays ATPase and GTPase activities
CS344_RS22105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS344_RS22120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CS344_RS22125	COG2823	Periplasmic or secreted lipoprotein
CS344_RS22140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS344_RS22150	COG1309	transcriptional regulator
CS344_RS22155	COG0471	metal ion transport
CS344_RS22160	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS344_RS22165	COG0772	Belongs to the SEDS family
CS344_RS22170	COG0768	penicillin binding
CS344_RS22180	COG1792	Involved in formation and maintenance of cell shape
CS344_RS22185	COG1077	Cell shape determining protein MreB Mrl
CS344_RS22190	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS344_RS22200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS344_RS22205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CS344_RS22210	COG0708	Exodeoxyribonuclease III
CS344_RS22215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS344_RS22220	COG2860	membrane
CS344_RS22230	COG0583	DNA-binding transcription factor activity
CS344_RS22235	COG0473	3-isopropylmalate dehydrogenase activity
CS344_RS22240	COG3391	amine dehydrogenase activity
CS344_RS22260	COG0583	DNA-binding transcription factor activity
CS344_RS22265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CS344_RS22270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS344_RS22275	COG0765	amino acid transport
CS344_RS22280	COG0765	amino acid transport
CS344_RS22285	COG1126	abc transporter atp-binding protein
CS344_RS22290	COG1794	racemase activity, acting on amino acids and derivatives
CS344_RS22295	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS344_RS22300	COG2223	nitrite transmembrane transporter activity
CS344_RS22305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS344_RS22305	COG2813	Specifically methylates the guanine in position
CS344_RS22315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS344_RS22340	COG2918	glutathione biosynthetic process
CS344_RS22360	COG0583	DNA-binding transcription factor activity
CS344_RS22365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CS344_RS22370	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS344_RS22405	COG0154	amidase activity
CS344_RS22415	COG1414	Transcriptional regulator
CS344_RS22435	COG2132	Multicopper oxidase
CS344_RS22455	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS344_RS22480	COG1024	Enoyl-CoA hydratase
CS344_RS22485	COG1024	Enoyl-CoA hydratase
CS344_RS22490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CS344_RS22500	COG0747	negative chemotaxis
CS344_RS22510	COG0601	transmembrane transport
CS344_RS22515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS22520	COG0444	Belongs to the ABC transporter superfamily
CS344_RS22525	COG4608	Belongs to the ABC transporter superfamily
CS344_RS22535	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS344_RS22540	COG0210	DNA helicase
CS344_RS22545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CS344_RS22550	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CS344_RS22560	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CS344_RS22570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CS344_RS22580	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CS344_RS22595	COG0356	it plays a direct role in the translocation of protons across the membrane
CS344_RS22610	COG1024	Enoyl-CoA hydratase
CS344_RS22630	COG0037	tRNA processing
CS344_RS22635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS344_RS22645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS344_RS22650	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CS344_RS22655	COG2967	ApaG domain
CS344_RS22660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS344_RS22665	COG0546	phosphoglycolate phosphatase activity
CS344_RS22675	COG0512	Glutamine amidotransferase of anthranilate synthase
CS344_RS22690	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS22710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS344_RS22720	COG1607	acyl-coa hydrolase
CS344_RS22765	COG3069	C4-dicarboxylate transmembrane transporter activity
CS344_RS22775	COG1802	Transcriptional regulator
CS344_RS22805	COG1595	DNA-templated transcription, initiation
CS344_RS22810	COG3712	iron ion homeostasis
CS344_RS22820	COG3720	iron ion transport
CS344_RS22825	COG4558	Periplasmic binding protein
CS344_RS22830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS344_RS22835	COG1120	ATPase activity
CS344_RS22840	COG1683	Conserved Protein
CS344_RS22870	COG3064	Membrane
CS344_RS22875	COG0583	DNA-binding transcription factor activity
CS344_RS22885	COG1234	tRNA 3'-trailer cleavage
CS344_RS22895	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CS344_RS22900	COG1802	Transcriptional regulator
CS344_RS22910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS344_RS22915	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS22930	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS22950	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS22965	COG2186	Transcriptional regulator
CS344_RS22970	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS22975	COG4948	Mandelate Racemase Muconate Lactonizing
CS344_RS22995	COG1053	succinate dehydrogenase
CS344_RS23015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS344_RS23025	COG0411	ABC transporter
CS344_RS23030	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS344_RS23055	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS344_RS23060	COG1024	Enoyl-CoA hydratase
CS344_RS23065	COG0022	dehydrogenase e1 component
CS344_RS23070	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CS344_RS23095	COG1960	acyl-CoA dehydrogenase activity
CS344_RS23100	COG1024	Enoyl-CoA hydratase
CS344_RS23105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS344_RS23125	COG1960	acyl-CoA dehydrogenase activity
CS344_RS23130	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS23135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS23145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS344_RS23160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS344_RS23165	COG1984	allophanate hydrolase subunit 2
CS344_RS23170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CS344_RS23175	COG0747	negative chemotaxis
CS344_RS23180	COG0601	transmembrane transport
CS344_RS23185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS23215	COG0511	ligase activity, forming carbon-carbon bonds
CS344_RS23220	COG0439	Biotin carboxylase
CS344_RS23235	COG0709	Synthesizes selenophosphate from selenide and ATP
CS344_RS23240	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CS344_RS23275	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS23285	COG0604	alcohol dehydrogenase
CS344_RS23295	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS23305	COG1960	acyl-CoA dehydrogenase activity
CS344_RS23310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS23315	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS23320	COG1024	Enoyl-CoA hydratase
CS344_RS23325	COG1902	pentaerythritol trinitrate reductase activity
CS344_RS23325	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS344_RS23330	COG1024	Enoyl-CoA hydratase
CS344_RS23335	COG1846	Transcriptional regulator
CS344_RS23350	COG4771	TonB-dependent receptor
CS344_RS23365	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS23370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS23375	COG0183	Belongs to the thiolase family
CS344_RS23380	COG2030	dehydratase
CS344_RS23385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS23425	COG3842	ATPase activity
CS344_RS23435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS344_RS23445	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CS344_RS23450	COG0583	DNA-binding transcription factor activity
CS344_RS23465	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS23475	COG0277	FAD linked oxidase domain protein
CS344_RS23480	COG1960	acyl-CoA dehydrogenase activity
CS344_RS23485	COG1960	acyl-CoA dehydrogenase activity
CS344_RS23495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS344_RS23510	COG2072	flavoprotein involved in K transport
CS344_RS23515	COG0604	alcohol dehydrogenase
CS344_RS23530	COG1024	Enoyl-CoA hydratase
CS344_RS23540	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS23555	COG1522	sequence-specific DNA binding
CS344_RS23565	COG3708	Transcriptional regulator
CS344_RS23565	COG2207	Transcriptional regulator
CS344_RS23580	COG2814	Major facilitator Superfamily
CS344_RS23605	COG1999	signal sequence binding
CS344_RS23650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS344_RS23675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS344_RS23685	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CS344_RS23690	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CS344_RS23700	COG0067	glutamate synthase
CS344_RS23700	COG0070	glutamate synthase
CS344_RS23700	COG0069	glutamate synthase activity
CS344_RS23710	COG3047	cAMP biosynthetic process
CS344_RS23720	COG1127	ABC transporter
CS344_RS23725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS344_RS23730	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS344_RS23735	COG2853	Lipoprotein
CS344_RS23745	COG1131	(ABC) transporter
CS344_RS23750	COG0842	Transport permease protein
CS344_RS23760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS344_RS23770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CS344_RS23775	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS344_RS23780	COG0131	Imidazoleglycerol-phosphate dehydratase
CS344_RS23790	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CS344_RS23795	COG0107	imidazoleglycerol-phosphate synthase activity
CS344_RS23805	COG0140	phosphoribosyl-ATP diphosphatase activity
CS344_RS23810	COG0537	adenosine 5'-monophosphoramidase activity
CS344_RS23815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS344_RS23820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS344_RS23840	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CS344_RS23845	COG1970	mechanosensitive ion channel activity
CS344_RS23850	COG0723	plastoquinol--plastocyanin reductase activity
CS344_RS23855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CS344_RS23860	COG2857	Cytochrome c1
CS344_RS23865	COG0625	glutathione transferase activity
CS344_RS23870	COG2969	positive regulation of protein catabolic process
CS344_RS23880	COG0582	viral genome integration into host DNA
CS344_RS23990	COG0583	DNA-binding transcription factor activity
CS344_RS23995	COG0492	ferredoxin-NADP+ reductase activity
CS344_RS24015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS24025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS344_RS24040	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS24075	COG3702	type iv secretory pathway
CS344_RS24095	COG3736	Type IV secretory pathway, component VirB8
CS344_RS24105	COG2948	multi-organism process
CS344_RS24110	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CS344_RS24120	COG0697	spore germination
CS344_RS24140	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CS344_RS24145	COG0747	negative chemotaxis
CS344_RS24150	COG0601	transmembrane transport
CS344_RS24155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS344_RS24165	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CS344_RS24175	COG0513	Belongs to the DEAD box helicase family
CS344_RS24180	COG1280	lysine exporter protein (LysE YggA)
CS344_RS24185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CS344_RS24205	COG0583	DNA-binding transcription factor activity
CS344_RS24215	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS344_RS24225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS344_RS24230	COG0154	amidase activity
CS344_RS24235	COG1609	Transcriptional regulator
CS344_RS24255	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS344_RS24260	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS344_RS24265	COG3842	ATPase activity
CS344_RS24270	COG1653	transport
CS344_RS24275	COG1175	transmembrane transport
CS344_RS24280	COG0395	ABC-type sugar transport system, permease component
CS344_RS24295	COG0018	arginyl-trna synthetase
CS344_RS24315	COG1280	lysine exporter protein (LysE YggA)
CS344_RS24330	COG1960	acyl-CoA dehydrogenase activity
CS344_RS24335	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CS344_RS24340	COG0183	Belongs to the thiolase family
CS344_RS24345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CS344_RS24360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS344_RS24365	COG3181	Tripartite tricarboxylate transporter family receptor
CS344_RS24375	COG2358	TRAP transporter, solute receptor (TAXI family
CS344_RS24385	COG1629	transport
CS344_RS24390	COG2922	Belongs to the Smg family
CS344_RS24395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS344_RS24415	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS344_RS24420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS24425	COG1028	Short-chain dehydrogenase reductase Sdr
CS344_RS24430	COG1012	belongs to the aldehyde dehydrogenase family
CS344_RS24440	COG0028	Belongs to the TPP enzyme family
CS344_RS24445	COG1522	sequence-specific DNA binding
CS344_RS24450	COG3781	membrane
CS344_RS24480	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS344_RS24505	COG1304	FMN binding
CS344_RS24520	COG0154	amidase activity
CS344_RS24525	COG1414	Transcriptional regulator
CS344_RS24550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CS344_RS24555	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CS344_RS24560	COG0594	ribonuclease P activity
CS344_RS24565	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CS344_RS24570	COG0706	membrane insertase activity
CS344_RS24575	COG0753	catalase activity
CS344_RS24580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS344_RS24585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS344_RS24595	COG2175	clavaminate synthase activity
CS344_RS24600	COG1473	amidohydrolase
CS344_RS24605	COG4608	Belongs to the ABC transporter superfamily
CS344_RS24610	COG0444	Belongs to the ABC transporter superfamily
CS344_RS24620	COG0601	transmembrane transport
CS344_RS24625	COG0747	negative chemotaxis
CS344_RS24665	COG0436	Aminotransferase
CS344_RS24670	COG1278	Cold shock