locus-tag	class	description
CS345_RS00005	COG0445	tRNA wobble uridine modification
CS345_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CS345_RS00015	COG1192	Involved in chromosome partitioning
CS345_RS00025	COG1475	DNA binding
CS345_RS00030	COG0252	asparaginase activity
CS345_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS345_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS345_RS00075	COG0081	regulation of translation
CS345_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CS345_RS00085	COG0222	ribosome binding
CS345_RS00090	COG0085	RNA polymerase activity
CS345_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CS345_RS00130	COG1230	cation diffusion facilitator family transporter
CS345_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CS345_RS00145	COG0049	tRNA binding
CS345_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS345_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS345_RS00160	COG0051	transcription antitermination factor activity, RNA binding
CS345_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CS345_RS00175	COG0089	rRNA binding
CS345_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CS345_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CS345_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CS345_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CS345_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
CS345_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CS345_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CS345_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CS345_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CS345_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CS345_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CS345_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CS345_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CS345_RS00270	COG1841	ribosomal large subunit assembly
CS345_RS00275	COG0200	Binds to the 23S rRNA
CS345_RS00280	COG0201	protein transport
CS345_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS345_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CS345_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CS345_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CS345_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CS345_RS00310	COG0202	RNA polymerase activity
CS345_RS00315	COG0203	ribosomal protein L17
CS345_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
CS345_RS00325	COG1324	tolerance protein
CS345_RS00330	COG4232	protein-disulfide reductase activity
CS345_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CS345_RS00355	COG1333	cytochrome c biogenesis protein
CS345_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS345_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CS345_RS00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CS345_RS00395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CS345_RS00410	COG2814	Major facilitator Superfamily
CS345_RS00415	COG0629	single-stranded DNA binding
CS345_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
CS345_RS00460	COG0438	transferase activity, transferring glycosyl groups
CS345_RS00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS00510	COG2186	Transcriptional regulator
CS345_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS00535	COG1956	GAF domain-containing protein
CS345_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS00570	COG0531	amino acid
CS345_RS00605	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CS345_RS00610	COG3568	Endonuclease Exonuclease Phosphatase
CS345_RS00615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS345_RS00625	COG0477	Major facilitator Superfamily
CS345_RS00635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS345_RS00645	COG0367	asparagine synthase
CS345_RS00665	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS345_RS00670	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS345_RS00710	COG0367	asparagine synthase
CS345_RS00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CS345_RS00740	COG0367	asparagine synthase
CS345_RS00750	COG0438	transferase activity, transferring glycosyl groups
CS345_RS00770	COG0438	transferase activity, transferring glycosyl groups
CS345_RS00775	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS345_RS00780	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CS345_RS00810	COG0859	PFAM glycosyl transferase family 9
CS345_RS00825	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CS345_RS00835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS345_RS00840	COG1127	ABC transporter
CS345_RS00860	COG1686	Belongs to the peptidase S11 family
CS345_RS00870	COG2921	Belongs to the UPF0250 family
CS345_RS00875	COG0321	lipoyl(octanoyl) transferase activity
CS345_RS00880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CS345_RS00900	COG2096	Adenosyltransferase
CS345_RS00910	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CS345_RS00925	COG0523	cobalamin synthesis protein
CS345_RS00930	COG0735	belongs to the Fur family
CS345_RS00945	COG0803	Belongs to the bacterial solute-binding protein 9 family
CS345_RS00955	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CS345_RS00965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CS345_RS00975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CS345_RS00980	COG1560	Kdo2-lipid A biosynthetic process
CS345_RS00990	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CS345_RS01010	COG1950	PFAM Membrane protein of
CS345_RS01020	COG0583	DNA-binding transcription factor activity
CS345_RS01030	COG0477	Major facilitator Superfamily
CS345_RS01045	COG0617	tRNA 3'-terminal CCA addition
CS345_RS01055	COG0513	Belongs to the DEAD box helicase family
CS345_RS01065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS345_RS01070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS345_RS01090	COG0438	transferase activity, transferring glycosyl groups
CS345_RS01115	COG0640	Transcriptional regulator
CS345_RS01175	COG0583	DNA-binding transcription factor activity
CS345_RS01190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CS345_RS01195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS01200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS01215	COG0758	DNA mediated transformation
CS345_RS01220	COG1522	sequence-specific DNA binding
CS345_RS01230	COG0242	peptide deformylase activity
CS345_RS01235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS345_RS01245	COG0546	phosphoglycolate phosphatase activity
CS345_RS01265	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS345_RS01270	COG1942	4-Oxalocrotonate Tautomerase
CS345_RS01275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS345_RS01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS345_RS01315	COG5000	phosphorelay sensor kinase activity
CS345_RS01320	COG2204	response regulator
CS345_RS01345	COG2068	MobA-Related Protein
CS345_RS01355	COG3473	Maleate cis-trans isomerase
CS345_RS01360	COG0596	Alpha beta hydrolase
CS345_RS01365	COG2309	aminopeptidase activity
CS345_RS01370	COG1335	isochorismatase
CS345_RS01395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS01420	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS345_RS01425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS01445	COG2226	methyltransferase
CS345_RS01460	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS01465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CS345_RS01470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CS345_RS01475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS345_RS01480	COG1054	Belongs to the UPF0176 family
CS345_RS01485	COG0588	phosphoglycerate mutase activity
CS345_RS01490	COG4942	peptidase
CS345_RS01495	COG0793	Belongs to the peptidase S41A family
CS345_RS01500	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS345_RS01520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS345_RS01550	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CS345_RS01555	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CS345_RS01560	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CS345_RS01565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CS345_RS01575	COG0142	geranyltranstransferase activity
CS345_RS01585	COG0583	DNA-binding transcription factor activity
CS345_RS01595	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CS345_RS01600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS01615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS345_RS01645	COG0601	transmembrane transport
CS345_RS01650	COG0747	negative chemotaxis
CS345_RS01665	COG0765	amino acid transport
CS345_RS01670	COG0765	amino acid transport
CS345_RS01675	COG1126	abc transporter atp-binding protein
CS345_RS01695	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS01705	COG1802	Transcriptional regulator
CS345_RS01720	COG1802	Transcriptional regulator
CS345_RS01730	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS01740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS01760	COG0028	Belongs to the TPP enzyme family
CS345_RS01770	COG0583	DNA-binding transcription factor activity
CS345_RS01775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS01780	COG2301	Belongs to the HpcH HpaI aldolase family
CS345_RS01785	COG2188	Transcriptional regulator
CS345_RS01830	COG0583	DNA-binding transcription factor activity
CS345_RS01835	COG1024	Enoyl-CoA hydratase
CS345_RS01870	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS01885	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS01910	COG0745	RESPONSE REGULATOR receiver
CS345_RS01945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CS345_RS01950	COG2890	protein-(glutamine-N5) methyltransferase activity
CS345_RS01955	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CS345_RS01965	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02000	COG1464	Belongs to the NlpA lipoprotein family
CS345_RS02035	COG4211	Belongs to the binding-protein-dependent transport system permease family
CS345_RS02040	COG0583	DNA-binding transcription factor activity
CS345_RS02045	COG0683	leucine binding
CS345_RS02050	COG0154	amidase activity
CS345_RS02055	COG0288	reversible hydration of carbon dioxide
CS345_RS02075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS345_RS02090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS345_RS02100	COG1414	Transcriptional regulator
CS345_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS02110	COG2031	fatty acid transporter
CS345_RS02115	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS02125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CS345_RS02130	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CS345_RS02140	COG4257	antibiotic catabolic process
CS345_RS02145	COG2808	Putative FMN-binding domain
CS345_RS02150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS345_RS02155	COG0747	negative chemotaxis
CS345_RS02160	COG0657	acetylesterase activity
CS345_RS02170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS345_RS02175	COG2207	Transcriptional regulator
CS345_RS02185	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CS345_RS02190	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CS345_RS02200	COG1538	Outer membrane efflux protein
CS345_RS02215	COG0583	DNA-binding transcription factor activity
CS345_RS02220	COG0628	permease
CS345_RS02230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS345_RS02235	COG0251	oxidation-reduction process
CS345_RS02245	COG0330	HflC and HflK could
CS345_RS02250	COG3422	double-strand break repair
CS345_RS02265	COG0583	DNA-binding transcription factor activity
CS345_RS02300	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02305	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS02310	COG1414	Transcriptional regulator
CS345_RS02315	COG1024	Enoyl-CoA hydratase
CS345_RS02320	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS02330	COG0604	alcohol dehydrogenase
CS345_RS02335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02340	COG0583	DNA-binding transcription factor activity
CS345_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02365	COG0251	oxidation-reduction process
CS345_RS02370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS345_RS02370	COG1017	nitric oxide dioxygenase activity
CS345_RS02375	COG2031	fatty acid transporter
CS345_RS02405	COG1278	Cold shock
CS345_RS02410	COG0583	DNA-binding transcription factor activity
CS345_RS02415	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02420	COG3119	arylsulfatase activity
CS345_RS02435	COG1228	amidohydrolase
CS345_RS02440	COG0523	cobalamin synthesis protein
CS345_RS02445	COG1819	glycosyl
CS345_RS02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS345_RS02490	COG1204	response to ionizing radiation
CS345_RS02515	COG0326	Molecular chaperone. Has ATPase activity
CS345_RS02520	COG0625	glutathione transferase activity
CS345_RS02535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS345_RS02540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CS345_RS02545	COG1652	LysM domain
CS345_RS02570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02575	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS345_RS02610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS02665	COG0583	DNA-binding transcription factor activity
CS345_RS02670	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02680	COG1024	Enoyl-CoA hydratase
CS345_RS02685	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02710	COG0028	Belongs to the TPP enzyme family
CS345_RS02715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02720	COG1024	Enoyl-CoA hydratase
CS345_RS02720	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS02725	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02730	COG1414	Transcriptional regulator
CS345_RS02750	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS02755	COG1609	Transcriptional regulator
CS345_RS02765	COG1053	succinate dehydrogenase
CS345_RS02765	COG3976	FMN-binding domain protein
CS345_RS02800	COG0683	leucine binding
CS345_RS02810	COG1309	transcriptional regulator
CS345_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS02835	COG1960	acyl-CoA dehydrogenase activity
CS345_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS02845	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS02855	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CS345_RS02865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CS345_RS02870	COG1053	succinate dehydrogenase
CS345_RS02880	COG2030	dehydratase
CS345_RS02890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS02900	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS02925	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS02945	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS345_RS02945	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS02960	COG0427	acetyl-CoA hydrolase
CS345_RS02965	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS02980	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CS345_RS02985	COG1960	acyl-CoA dehydrogenase activity
CS345_RS03000	COG0183	Belongs to the thiolase family
CS345_RS03005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS345_RS03015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS03020	COG0583	DNA-binding transcription factor activity
CS345_RS03025	COG1960	acyl-CoA dehydrogenase activity
CS345_RS03040	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CS345_RS03065	COG1309	transcriptional regulator
CS345_RS03075	COG1024	Enoyl-CoA hydratase
CS345_RS03095	COG1024	Enoyl-CoA hydratase
CS345_RS03100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS03105	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03110	COG1454	alcohol dehydrogenase
CS345_RS03115	COG1024	Enoyl-CoA hydratase
CS345_RS03135	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS03140	COG0431	NADPH-dependent FMN reductase
CS345_RS03145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS03150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS345_RS03165	COG1414	Transcriptional regulator
CS345_RS03170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS345_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS03180	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS03195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS03205	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03230	COG1960	acyl-CoA dehydrogenase activity
CS345_RS03255	COG1024	Enoyl-CoA hydratase
CS345_RS03265	COG1960	acyl-CoA dehydrogenase activity
CS345_RS03270	COG1024	Enoyl-CoA hydratase
CS345_RS03275	COG0183	Belongs to the thiolase family
CS345_RS03280	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03295	COG0583	DNA-binding transcription factor activity
CS345_RS03300	COG2267	carboxylic ester hydrolase activity
CS345_RS03315	COG0625	glutathione transferase activity
CS345_RS03320	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03330	COG2186	Transcriptional regulator
CS345_RS03335	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS03340	COG0626	cystathionine gamma-synthase activity
CS345_RS03380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS03385	COG0436	Aminotransferase
CS345_RS03395	COG0765	amino acid transport
CS345_RS03405	COG1473	amidohydrolase
CS345_RS03410	COG1414	Transcriptional regulator
CS345_RS03420	COG0154	amidase activity
CS345_RS03480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS03495	COG3135	benzoate transporter
CS345_RS03520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS345_RS03525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS03530	COG1335	isochorismatase
CS345_RS03545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS03580	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03585	COG0543	2 iron, 2 sulfur cluster binding
CS345_RS03585	COG0633	Ferredoxin
CS345_RS03590	COG4638	Rieske (2fe-2S)
CS345_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS03610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS345_RS03630	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS03635	COG3384	dioxygenase
CS345_RS03645	COG3971	2-oxopent-4-enoate hydratase activity
CS345_RS03700	COG1024	Enoyl-CoA hydratase
CS345_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS03710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS03725	COG1960	acyl-CoA dehydrogenase activity
CS345_RS03770	COG0183	Belongs to the thiolase family
CS345_RS03775	COG2030	dehydratase
CS345_RS03785	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS03825	COG1459	type II secretion system
CS345_RS03830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CS345_RS03835	COG3267	Type II secretory pathway component ExeA
CS345_RS03835	COG3409	Peptidoglycan-binding domain 1 protein
CS345_RS03845	COG1450	Type ii and iii secretion system protein
CS345_RS03910	COG5444	nuclease activity
CS345_RS04020	COG0387	Pfam Sodium calcium exchanger
CS345_RS04030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS345_RS04080	COG4772	TonB-dependent receptor
CS345_RS04090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS345_RS04115	COG1054	Belongs to the UPF0176 family
CS345_RS04130	COG0489	protein tyrosine kinase activity
CS345_RS04175	COG2081	HI0933 family
CS345_RS04180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS345_RS04190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS345_RS04195	COG0509	glycine decarboxylation via glycine cleavage system
CS345_RS04200	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS345_RS04200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS345_RS04220	COG1024	Enoyl-CoA hydratase
CS345_RS04240	COG4172	Belongs to the ABC transporter superfamily
CS345_RS04245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS04250	COG0601	transmembrane transport
CS345_RS04255	COG0747	negative chemotaxis
CS345_RS04265	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS345_RS04270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS04290	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CS345_RS04295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS345_RS04300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS345_RS04315	COG0438	transferase activity, transferring glycosyl groups
CS345_RS04330	COG0438	transferase activity, transferring glycosyl groups
CS345_RS04335	COG0438	transferase activity, transferring glycosyl groups
CS345_RS04340	COG0166	Belongs to the GPI family
CS345_RS04355	COG0277	FAD linked oxidase domain protein
CS345_RS04360	COG0745	RESPONSE REGULATOR receiver
CS345_RS04365	COG0642	Histidine kinase
CS345_RS04370	COG1368	sulfuric ester hydrolase activity
CS345_RS04405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CS345_RS04420	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CS345_RS04450	COG0012	GTP binding
CS345_RS04460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CS345_RS04480	COG0556	nucleotide-excision repair
CS345_RS04520	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS04525	COG1309	transcriptional regulator
CS345_RS04535	COG2814	Major facilitator Superfamily
CS345_RS04560	COG0280	phosphate acetyltransferase
CS345_RS04560	COG0281	malic enzyme
CS345_RS04570	COG0601	transmembrane transport
CS345_RS04575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS04580	COG4172	Belongs to the ABC transporter superfamily
CS345_RS04585	COG0747	negative chemotaxis
CS345_RS04595	COG0583	DNA-binding transcription factor activity
CS345_RS04610	COG0640	Transcriptional regulator
CS345_RS04625	COG3135	benzoate transporter
CS345_RS04630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS345_RS04635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CS345_RS04640	COG0742	ribosomal rna small subunit methyltransferase
CS345_RS04655	COG3639	organic phosphonate transmembrane transporter activity
CS345_RS04660	COG3639	organic phosphonate transmembrane transporter activity
CS345_RS04665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS345_RS04690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CS345_RS04695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS345_RS04705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CS345_RS04710	COG1058	Belongs to the CinA family
CS345_RS04710	COG1546	Belongs to the CinA family
CS345_RS04715	COG0284	orotidine-5'-phosphate decarboxylase activity
CS345_RS04720	COG1252	NADH dehydrogenase
CS345_RS04735	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS04745	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CS345_RS04765	COG1053	succinate dehydrogenase
CS345_RS04780	COG0583	DNA-binding transcription factor activity
CS345_RS04790	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS04795	COG1414	Transcriptional regulator
CS345_RS04810	COG1335	isochorismatase
CS345_RS04825	COG0405	Gamma-glutamyltransferase
CS345_RS04840	COG1960	acyl-CoA dehydrogenase activity
CS345_RS04845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS04850	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS04855	COG0583	DNA-binding transcription factor activity
CS345_RS04880	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS04885	COG0583	DNA-binding transcription factor activity
CS345_RS04890	COG2199	diguanylate cyclase activity
CS345_RS04915	COG3842	ATPase activity
CS345_RS04940	COG1024	Enoyl-CoA hydratase
CS345_RS04940	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS04945	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS04960	COG4172	Belongs to the ABC transporter superfamily
CS345_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS04995	COG2423	ornithine cyclodeaminase activity
CS345_RS05005	COG0473	3-isopropylmalate dehydrogenase activity
CS345_RS05010	COG0066	3-isopropylmalate dehydratase activity
CS345_RS05015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS345_RS05025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS05035	COG0583	DNA-binding transcription factor activity
CS345_RS05050	COG0583	DNA-binding transcription factor activity
CS345_RS05060	COG1024	Enoyl-CoA hydratase
CS345_RS05070	COG2084	Dehydrogenase
CS345_RS05090	COG1850	ribulose-bisphosphate carboxylase activity
CS345_RS05100	COG0583	DNA-binding transcription factor activity
CS345_RS05105	COG1024	Enoyl-CoA hydratase
CS345_RS05130	COG3842	ATPase activity
CS345_RS05135	COG1177	transmembrane transport
CS345_RS05140	COG0436	Aminotransferase
CS345_RS05150	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05155	COG3386	PFAM SMP-30 Gluconolaconase
CS345_RS05165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS345_RS05185	COG0583	DNA-binding transcription factor activity
CS345_RS05195	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS05210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS05250	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS05285	COG1802	Transcriptional regulator
CS345_RS05290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS05325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05340	COG0183	Belongs to the thiolase family
CS345_RS05345	COG1024	Enoyl-CoA hydratase
CS345_RS05355	COG1024	Enoyl-CoA hydratase
CS345_RS05360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05365	COG0583	DNA-binding transcription factor activity
CS345_RS05370	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05390	COG0583	DNA-binding transcription factor activity
CS345_RS05395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05400	COG1960	acyl-CoA dehydrogenase activity
CS345_RS05405	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CS345_RS05415	COG4191	Histidine kinase
CS345_RS05420	COG4566	intracellular signal transduction
CS345_RS05450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS05460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS345_RS05480	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05505	COG0583	DNA-binding transcription factor activity
CS345_RS05525	COG1024	Enoyl-CoA hydratase
CS345_RS05530	COG1024	Enoyl-CoA hydratase
CS345_RS05535	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS05540	COG1960	acyl-CoA dehydrogenase activity
CS345_RS05575	COG3795	YCII-related domain
CS345_RS05580	COG2188	Transcriptional regulator
CS345_RS05600	COG0154	amidase activity
CS345_RS05605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05610	COG1024	Enoyl-CoA hydratase
CS345_RS05620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS05635	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS05640	COG1414	Transcriptional regulator
CS345_RS05655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS345_RS05660	COG0251	oxidation-reduction process
CS345_RS05665	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS05685	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS05690	COG0583	DNA-binding transcription factor activity
CS345_RS05700	COG0590	tRNA wobble adenosine to inosine editing
CS345_RS05705	COG2807	transmembrane transport
CS345_RS05710	COG0307	riboflavin synthase, alpha
CS345_RS05715	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS05720	COG1522	sequence-specific DNA binding
CS345_RS05730	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS05740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS05750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS345_RS05760	COG1063	alcohol dehydrogenase
CS345_RS05780	COG1418	mRNA catabolic process
CS345_RS05785	COG1448	Aminotransferase
CS345_RS05790	COG1335	isochorismatase
CS345_RS05815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS345_RS05820	COG2274	protein secretion by the type I secretion system
CS345_RS05830	COG1538	Outer membrane efflux protein
CS345_RS05835	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS345_RS05835	COG0493	'glutamate synthase
CS345_RS05845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CS345_RS05855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS05865	COG1309	transcriptional regulator
CS345_RS05870	COG1960	acyl-CoA dehydrogenase activity
CS345_RS05875	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS05880	COG2076	Multidrug Resistance protein
CS345_RS05885	COG1309	transcriptional regulator
CS345_RS05895	COG0583	DNA-binding transcription factor activity
CS345_RS05910	COG0840	transmembrane signaling receptor activity
CS345_RS05925	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS05950	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS05960	COG1024	Enoyl-CoA hydratase
CS345_RS05970	COG2203	Gaf domain
CS345_RS05970	COG2199	diguanylate cyclase activity
CS345_RS05985	COG0456	acetyltransferase
CS345_RS05995	COG0154	amidase activity
CS345_RS06000	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS06000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS06010	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS06025	COG3945	hemerythrin HHE cation binding domain
CS345_RS06040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS345_RS06040	COG2169	Transcriptional regulator
CS345_RS06060	COG1271	oxidase subunit
CS345_RS06065	COG1294	oxidase, subunit
CS345_RS06075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS06105	COG0596	Alpha beta hydrolase
CS345_RS06110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS345_RS06150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS345_RS06155	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CS345_RS06165	COG2070	2-Nitropropane dioxygenase
CS345_RS06180	COG1917	Cupin 2, conserved barrel domain protein
CS345_RS06180	COG2207	Transcriptional regulator
CS345_RS06200	COG2900	Belongs to the SlyX family
CS345_RS06210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS345_RS06240	COG0583	DNA-binding transcription factor activity
CS345_RS06245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS06255	COG0583	DNA-binding transcription factor activity
CS345_RS06280	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CS345_RS06290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS345_RS06295	COG1845	cytochrome c oxidase, subunit III
CS345_RS06300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS345_RS06305	COG0640	Transcriptional regulator
CS345_RS06355	COG4942	peptidase
CS345_RS06370	COG1666	GTP binding
CS345_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS06405	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS345_RS06410	COG1845	cytochrome c oxidase, subunit III
CS345_RS06415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS345_RS06420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CS345_RS06425	COG0477	Major facilitator Superfamily
CS345_RS06440	COG5006	permease, DMT superfamily
CS345_RS06460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CS345_RS06470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CS345_RS06475	COG3383	formate dehydrogenase (NAD+) activity
CS345_RS06495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CS345_RS06500	COG0303	'Molybdopterin
CS345_RS06505	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS345_RS06515	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CS345_RS06520	COG0315	cyclic pyranopterin monophosphate synthase activity
CS345_RS06530	COG0412	Dienelactone hydrolase
CS345_RS06540	COG0678	peroxiredoxin activity
CS345_RS06550	COG0697	spore germination
CS345_RS06595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS345_RS06600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CS345_RS06605	COG1335	isochorismatase
CS345_RS06610	COG0523	cobalamin synthesis protein
CS345_RS06640	COG1802	Transcriptional regulator
CS345_RS06660	COG0667	Aldo Keto reductase
CS345_RS06665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CS345_RS06670	COG4535	Mg2 and Co2 transporter CorC
CS345_RS06675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CS345_RS06680	COG1702	phosphate starvation-inducible protein PhoH
CS345_RS06685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS345_RS06695	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS345_RS06700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS345_RS06705	COG1862	Preprotein translocase
CS345_RS06710	COG0343	queuine tRNA-ribosyltransferase activity
CS345_RS06715	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CS345_RS06720	COG2027	D-alanyl-D-alanine carboxypeptidase
CS345_RS06760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CS345_RS06765	COG0741	lytic transglycosylase activity
CS345_RS06775	COG0436	Aminotransferase
CS345_RS06785	COG0280	phosphate acetyltransferase
CS345_RS06785	COG0281	malic enzyme
CS345_RS06795	COG2732	(Barnase) inhibitor
CS345_RS06800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CS345_RS06805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS345_RS06810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CS345_RS06815	COG0126	phosphoglycerate kinase activity
CS345_RS06820	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CS345_RS06825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS345_RS06840	COG0625	glutathione transferase activity
CS345_RS06870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CS345_RS06880	COG0306	phosphate transporter
CS345_RS06885	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS345_RS06895	COG0739	heme binding
CS345_RS06905	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS345_RS06955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CS345_RS06965	COG2944	sequence-specific DNA binding
CS345_RS06975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CS345_RS06980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CS345_RS06985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CS345_RS06990	COG0009	L-threonylcarbamoyladenylate synthase
CS345_RS06995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS07000	COG1414	Transcriptional regulator
CS345_RS07015	COG0765	amino acid transport
CS345_RS07020	COG1126	abc transporter atp-binding protein
CS345_RS07025	COG0028	Belongs to the TPP enzyme family
CS345_RS07040	COG0028	Belongs to the TPP enzyme family
CS345_RS07045	COG0583	DNA-binding transcription factor activity
CS345_RS07050	COG4974	Belongs to the 'phage' integrase family
CS345_RS07055	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CS345_RS07060	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CS345_RS07070	COG1686	Belongs to the peptidase S11 family
CS345_RS07080	COG2814	Major facilitator Superfamily
CS345_RS07090	COG1074	ATP-dependent DNA helicase activity
CS345_RS07100	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS345_RS07115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS07120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS345_RS07130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS07140	COG0505	Belongs to the CarA family
CS345_RS07145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CS345_RS07150	COG4221	oxidoreductase activity
CS345_RS07155	COG0406	alpha-ribazole phosphatase activity
CS345_RS07165	COG3842	ATPase activity
CS345_RS07185	COG2233	PERMEase
CS345_RS07190	COG0840	transmembrane signaling receptor activity
CS345_RS07195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS345_RS07200	COG1534	Rna-binding protein
CS345_RS07210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS345_RS07230	COG0248	Ppx GppA phosphatase
CS345_RS07270	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS07280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS07285	COG3620	sequence-specific DNA binding
CS345_RS07345	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS07375	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS07410	COG2072	flavoprotein involved in K transport
CS345_RS07415	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS07445	COG1137	ATPase activity
CS345_RS07455	COG0154	amidase activity
CS345_RS07460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS07485	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS07490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS07495	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS07505	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS345_RS07515	COG1522	sequence-specific DNA binding
CS345_RS07520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS345_RS07525	COG1473	amidohydrolase
CS345_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS07535	COG4597	amino acid ABC transporter
CS345_RS07540	COG0765	amino acid transport
CS345_RS07545	COG1126	abc transporter atp-binding protein
CS345_RS07555	COG0436	Aminotransferase
CS345_RS07560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS345_RS07605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CS345_RS07625	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS07630	COG3546	catalase activity
CS345_RS07635	COG2985	domain, Protein
CS345_RS07640	COG0583	DNA-binding transcription factor activity
CS345_RS07675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS345_RS07695	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS07715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS345_RS07725	COG1132	(ABC) transporter
CS345_RS07750	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CS345_RS07760	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS07770	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CS345_RS07780	COG0511	ligase activity, forming carbon-carbon bonds
CS345_RS07805	COG2188	Transcriptional regulator
CS345_RS07810	COG0439	Biotin carboxylase
CS345_RS07820	COG0511	ligase activity, forming carbon-carbon bonds
CS345_RS07835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS07865	COG3971	2-oxopent-4-enoate hydratase activity
CS345_RS07870	COG0583	DNA-binding transcription factor activity
CS345_RS07885	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS345_RS07925	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS345_RS07935	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS07975	COG0251	oxidation-reduction process
CS345_RS07980	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS08010	COG4789	Type iii secretion
CS345_RS08110	COG4790	Type iii secretion
CS345_RS08115	COG4794	Type iii secretion
CS345_RS08120	COG4791	protein targeting
CS345_RS08125	COG4792	protein secretion
CS345_RS08140	COG1595	DNA-templated transcription, initiation
CS345_RS08160	COG2208	phosphoserine phosphatase activity
CS345_RS08160	COG2770	Histidine kinase
CS345_RS08170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS345_RS08175	COG2172	sigma factor antagonist activity
CS345_RS08180	COG1366	Belongs to the anti-sigma-factor antagonist family
CS345_RS08185	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS345_RS08235	COG2321	neutral zinc metallopeptidase
CS345_RS08240	COG0009	L-threonylcarbamoyladenylate synthase
CS345_RS08245	COG1994	Peptidase M50
CS345_RS08250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS08255	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CS345_RS08260	COG3539	Fimbrial protein
CS345_RS08270	COG2850	peptidyl-arginine hydroxylation
CS345_RS08280	COG3360	Dodecin
CS345_RS08315	COG0668	transmembrane transport
CS345_RS08335	COG0483	inositol monophosphate 1-phosphatase activity
CS345_RS08340	COG1253	flavin adenine dinucleotide binding
CS345_RS08350	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS345_RS08360	COG3063	Type IV pilus biogenesis stability protein PilW
CS345_RS08375	COG0825	malonyl-CoA metabolic process
CS345_RS08380	COG0037	tRNA processing
CS345_RS08385	COG0527	aspartate kinase activity
CS345_RS08405	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS08410	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS08410	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS08425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS345_RS08435	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS08445	COG0583	DNA-binding transcription factor activity
CS345_RS08470	COG3842	ATPase activity
CS345_RS08480	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS08480	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS345_RS08485	COG1414	Transcriptional regulator
CS345_RS08490	COG1832	CoA-binding protein
CS345_RS08500	COG0251	oxidation-reduction process
CS345_RS08525	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS08535	COG1215	transferase activity, transferring glycosyl groups
CS345_RS08540	COG0726	polysaccharide deacetylase
CS345_RS08540	COG1649	PFAM Uncharacterised BCR, COG1649
CS345_RS08560	COG1846	Transcriptional regulator
CS345_RS08585	COG2010	Cytochrome c
CS345_RS08585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS345_RS08590	COG2080	2 iron, 2 sulfur cluster binding
CS345_RS08595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS345_RS08600	COG3473	Maleate cis-trans isomerase
CS345_RS08605	COG0596	Alpha beta hydrolase
CS345_RS08610	COG2309	aminopeptidase activity
CS345_RS08615	COG1335	isochorismatase
CS345_RS08620	COG2010	Cytochrome c
CS345_RS08620	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS345_RS08625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS345_RS08625	COG1017	nitric oxide dioxygenase activity
CS345_RS08650	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS08660	COG0183	Belongs to the thiolase family
CS345_RS08665	COG1024	Enoyl-CoA hydratase
CS345_RS08665	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS08680	COG0183	Belongs to the thiolase family
CS345_RS08695	COG2197	response regulator
CS345_RS08710	COG0166	Belongs to the GPI family
CS345_RS08715	COG1045	serine acetyltransferase
CS345_RS08725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS345_RS08730	COG0483	inositol monophosphate 1-phosphatase activity
CS345_RS08740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS345_RS08755	COG0210	DNA helicase
CS345_RS08760	COG0598	Magnesium transport protein CorA
CS345_RS08770	COG0747	negative chemotaxis
CS345_RS08775	COG0601	transmembrane transport
CS345_RS08780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS08785	COG4172	Belongs to the ABC transporter superfamily
CS345_RS08790	COG1846	Transcriptional regulator
CS345_RS08835	COG4964	Belongs to the GSP D family
CS345_RS08900	COG3474	cytochrome
CS345_RS08905	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CS345_RS08920	COG3384	dioxygenase
CS345_RS08925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS345_RS08945	COG2885	chlorophyll binding
CS345_RS08980	COG0697	spore germination
CS345_RS08985	COG0730	response to heat
CS345_RS09000	COG3264	Mechanosensitive ion channel
CS345_RS09000	COG1511	domain protein
CS345_RS09005	COG0583	DNA-binding transcription factor activity
CS345_RS09010	COG0427	acetyl-CoA hydrolase
CS345_RS09015	COG0385	Bile acid
CS345_RS09055	COG3012	SEC-C Motif Domain Protein
CS345_RS09065	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS09070	COG0154	amidase activity
CS345_RS09080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CS345_RS09095	COG0495	leucyl-tRNA aminoacylation
CS345_RS09100	COG2814	Major facilitator Superfamily
CS345_RS09120	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CS345_RS09125	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CS345_RS09130	COG2814	Major facilitator Superfamily
CS345_RS09135	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CS345_RS09145	COG4176	ABC-type proline glycine betaine transport system permease component
CS345_RS09155	COG1942	4-Oxalocrotonate Tautomerase
CS345_RS09160	COG0183	Belongs to the thiolase family
CS345_RS09170	COG1802	Transcriptional regulator
CS345_RS09180	COG1024	Enoyl-CoA hydratase
CS345_RS09185	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS09195	COG2032	superoxide dismutase activity
CS345_RS09210	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS345_RS09235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS345_RS09240	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS345_RS09250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CS345_RS09255	COG0736	holo-[acyl-carrier-protein] synthase activity
CS345_RS09270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CS345_RS09280	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS345_RS09280	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS345_RS09285	COG2224	Isocitrate lyase
CS345_RS09295	COG1346	cytolysis
CS345_RS09300	COG1380	Effector of murein hydrolase LrgA
CS345_RS09305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CS345_RS09305	COG4106	trans-aconitate 2-methyltransferase activity
CS345_RS09315	COG0156	8-amino-7-oxononanoate synthase activity
CS345_RS09335	COG3278	Belongs to the heme-copper respiratory oxidase family
CS345_RS09380	COG1131	(ABC) transporter
CS345_RS09385	COG0842	Transport permease protein
CS345_RS09390	COG0628	permease
CS345_RS09405	COG2814	Major facilitator Superfamily
CS345_RS09410	COG2841	Protein conserved in bacteria
CS345_RS09435	COG0765	amino acid transport
CS345_RS09440	COG0765	amino acid transport
CS345_RS09445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS09480	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS09485	COG1595	DNA-templated transcription, initiation
CS345_RS09495	COG3530	Putative quorum-sensing-regulated virulence factor
CS345_RS09500	COG0494	nUDIX hydrolase
CS345_RS09515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS345_RS09520	COG0542	response to heat
CS345_RS09525	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS09535	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS09545	COG5441	Belongs to the UPF0261 family
CS345_RS09550	COG5564	TIM-barrel signal transduction protein
CS345_RS09565	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS345_RS09580	COG1477	protein flavinylation
CS345_RS09600	COG1131	(ABC) transporter
CS345_RS09605	COG0842	Transport permease protein
CS345_RS09615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CS345_RS09620	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS345_RS09620	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS345_RS09625	COG1562	ergosterol biosynthetic process
CS345_RS09630	COG1562	ergosterol biosynthetic process
CS345_RS09635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS345_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS09655	COG2304	oxidoreductase activity
CS345_RS09675	COG0534	Mate efflux family protein
CS345_RS09690	COG3483	tryptophan 2,3-dioxygenase activity
CS345_RS09695	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CS345_RS09700	COG2003	Belongs to the UPF0758 family
CS345_RS09705	COG1047	Peptidyl-prolyl cis-trans
CS345_RS09710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CS345_RS09715	COG0625	glutathione transferase activity
CS345_RS09735	COG0523	cobalamin synthesis protein
CS345_RS09745	COG0583	DNA-binding transcription factor activity
CS345_RS09755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CS345_RS09760	COG1187	pseudouridine synthase activity
CS345_RS09765	COG0779	Required for maturation of 30S ribosomal subunits
CS345_RS09770	COG2251	uridine kinase activity
CS345_RS09770	COG0195	Participates in both transcription termination and antitermination
CS345_RS09775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CS345_RS09780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CS345_RS09785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CS345_RS09805	COG1611	Belongs to the LOG family
CS345_RS09820	COG0412	Dienelactone hydrolase
CS345_RS09825	COG1283	sodium-dependent phosphate transmembrane transporter activity
CS345_RS09830	COG1760	l-serine dehydratase
CS345_RS09835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CS345_RS09840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CS345_RS09850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CS345_RS09875	COG2311	Membrane
CS345_RS09885	COG2358	TRAP transporter, solute receptor (TAXI family
CS345_RS09890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS345_RS09905	COG0456	acetyltransferase
CS345_RS09920	COG5285	phytanoyl-CoA dioxygenase
CS345_RS09930	COG3395	kinase activity
CS345_RS09935	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS345_RS09950	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CS345_RS09960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS09985	COG0747	negative chemotaxis
CS345_RS09990	COG0601	transmembrane transport
CS345_RS09995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS10000	COG4172	Belongs to the ABC transporter superfamily
CS345_RS10005	COG0154	amidase activity
CS345_RS10050	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CS345_RS10055	COG0425	Belongs to the sulfur carrier protein TusA family
CS345_RS10065	COG0228	four-way junction DNA binding
CS345_RS10075	COG0336	Belongs to the RNA methyltransferase TrmD family
CS345_RS10080	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CS345_RS10090	COG0642	Histidine kinase
CS345_RS10105	COG0525	valine-tRNA ligase activity
CS345_RS10110	COG0105	UTP biosynthetic process
CS345_RS10115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CS345_RS10135	COG2976	Protein conserved in bacteria
CS345_RS10140	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS345_RS10145	COG1160	GTP binding
CS345_RS10155	COG1923	regulation of RNA biosynthetic process
CS345_RS10160	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CS345_RS10165	COG0330	HflC and HflK could
CS345_RS10170	COG0330	HflC and HflK could
CS345_RS10180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CS345_RS10185	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CS345_RS10190	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CS345_RS10200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS345_RS10210	COG4680	protein conserved in bacteria
CS345_RS10260	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS10270	COG4638	Rieske (2fe-2S)
CS345_RS10290	COG0633	Ferredoxin
CS345_RS10295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS10325	COG0583	DNA-binding transcription factor activity
CS345_RS10340	COG0028	Belongs to the TPP enzyme family
CS345_RS10345	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS10350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS10370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CS345_RS10380	COG3829	transcription factor binding
CS345_RS10410	COG0833	amino acid
CS345_RS10425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS345_RS10430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CS345_RS10435	COG0840	transmembrane signaling receptor activity
CS345_RS10465	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS10505	COG5265	(ABC) transporter
CS345_RS10515	COG0667	Aldo Keto reductase
CS345_RS10530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS345_RS10570	COG1959	2 iron, 2 sulfur cluster binding
CS345_RS10575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS10580	COG0587	DNA-directed DNA polymerase activity
CS345_RS10595	COG0400	carboxylic ester hydrolase activity
CS345_RS10605	COG1566	PFAM secretion protein HlyD family protein
CS345_RS10630	COG0235	Class ii aldolase
CS345_RS10635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS10640	COG0720	synthase
CS345_RS10645	COG0602	queuosine metabolic process
CS345_RS10670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS10705	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS10730	COG3842	ATPase activity
CS345_RS10735	COG3842	ATPase activity
CS345_RS10745	COG0395	ABC-type sugar transport system, permease component
CS345_RS10775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS10780	COG0420	3'-5' exonuclease activity
CS345_RS10790	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS10795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CS345_RS10795	COG2111	Na H antiporter
CS345_RS10800	COG1006	Multisubunit Na H antiporter MnhC subunit
CS345_RS10805	COG0651	ATP synthesis coupled electron transport
CS345_RS10810	COG1863	multisubunit Na H antiporter MnhE subunit
CS345_RS10815	COG2212	antiporter activity
CS345_RS10835	COG0590	tRNA wobble adenosine to inosine editing
CS345_RS10840	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS345_RS10845	COG1024	Enoyl-CoA hydratase
CS345_RS10850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS10860	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS10865	COG0488	(ABC) transporter
CS345_RS10895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS345_RS10900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS345_RS10905	COG2252	PERMEase
CS345_RS10910	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CS345_RS10915	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CS345_RS10950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CS345_RS10955	COG0789	Transcriptional regulator
CS345_RS10965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS345_RS10965	COG0678	peroxiredoxin activity
CS345_RS10975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CS345_RS10980	COG0584	glycerophosphoryl diester phosphodiesterase
CS345_RS10985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS345_RS10995	COG4181	ATPase activity
CS345_RS11020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS11045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS11045	COG2205	protein histidine kinase activity
CS345_RS11050	COG2197	response regulator
CS345_RS11070	COG3121	Chaperone
CS345_RS11075	COG3188	usher protein
CS345_RS11080	COG3539	Fimbrial protein
CS345_RS11085	COG2831	hemolysin activation secretion protein
CS345_RS11100	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS11125	COG0583	DNA-binding transcription factor activity
CS345_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS11150	COG0765	amino acid transport
CS345_RS11155	COG1126	abc transporter atp-binding protein
CS345_RS11160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS345_RS11165	COG1758	RNA polymerase activity
CS345_RS11170	COG0194	GDP metabolic process
CS345_RS11175	COG3258	Cytochrome c
CS345_RS11180	COG2863	cytochrome
CS345_RS11185	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS11190	COG0791	NLP P60 protein
CS345_RS11195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS345_RS11215	COG1561	YicC-like family, N-terminal region
CS345_RS11220	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CS345_RS11240	COG5002	protein histidine kinase activity
CS345_RS11240	COG5001	Diguanylate cyclase
CS345_RS11245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CS345_RS11250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS345_RS11255	COG0174	glutamine synthetase
CS345_RS11265	COG2204	response regulator
CS345_RS11270	COG0583	DNA-binding transcription factor activity
CS345_RS11275	COG1741	Belongs to the pirin family
CS345_RS11280	COG1741	Belongs to the pirin family
CS345_RS11285	COG3842	ATPase activity
CS345_RS11290	COG1178	ABC-type Fe3 transport system permease component
CS345_RS11295	COG1840	ABC-type Fe3 transport system, periplasmic component
CS345_RS11305	COG0583	DNA-binding transcription factor activity
CS345_RS11310	COG2814	Major facilitator Superfamily
CS345_RS11315	COG0656	L-ascorbic acid biosynthetic process
CS345_RS11330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CS345_RS11335	COG0583	DNA-binding transcription factor activity
CS345_RS11350	COG0783	Belongs to the Dps family
CS345_RS11365	COG0463	Glycosyl transferase, family 2
CS345_RS11385	COG0438	transferase activity, transferring glycosyl groups
CS345_RS11400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS345_RS11420	COG0300	oxidoreductase activity
CS345_RS11430	COG0156	8-amino-7-oxononanoate synthase activity
CS345_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS11435	COG3321	synthase
CS345_RS11435	COG0604	alcohol dehydrogenase
CS345_RS11450	COG3842	ATPase activity
CS345_RS11455	COG0395	ABC-type sugar transport system, permease component
CS345_RS11460	COG1175	transmembrane transport
CS345_RS11465	COG1653	transport
CS345_RS11475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CS345_RS11485	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS11505	COG1794	racemase activity, acting on amino acids and derivatives
CS345_RS11510	COG0625	glutathione transferase activity
CS345_RS11515	COG2133	pyrroloquinoline quinone binding
CS345_RS11525	COG0697	spore germination
CS345_RS11530	COG2363	Small membrane protein
CS345_RS11545	COG1464	Belongs to the NlpA lipoprotein family
CS345_RS11555	COG0688	phosphatidylethanolamine metabolic process
CS345_RS11570	COG0095	Lipoate-protein ligase
CS345_RS11585	COG0625	glutathione transferase activity
CS345_RS11590	COG0386	Belongs to the glutathione peroxidase family
CS345_RS11610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS11630	COG2259	Doxx family
CS345_RS11645	COG0667	Aldo Keto reductase
CS345_RS11690	COG1640	4-alpha-glucanotransferase
CS345_RS11705	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS345_RS11715	COG0366	Alpha amylase catalytic
CS345_RS11720	COG0297	glycogen (starch) synthase activity
CS345_RS11730	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS345_RS11735	COG2204	response regulator
CS345_RS11740	COG2204	response regulator
CS345_RS11745	COG0028	Belongs to the TPP enzyme family
CS345_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS11805	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CS345_RS11810	COG4575	ribosome binding
CS345_RS11845	COG0392	lysyltransferase activity
CS345_RS11850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS345_RS11855	COG3568	Endonuclease Exonuclease Phosphatase
CS345_RS11865	COG1695	Transcriptional regulator
CS345_RS11875	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS11885	COG0583	DNA-binding transcription factor activity
CS345_RS11900	COG1802	Transcriptional regulator
CS345_RS11910	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS11920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS11925	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS11935	COG0066	3-isopropylmalate dehydratase activity
CS345_RS11940	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS345_RS11945	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS11950	COG4948	Mandelate Racemase Muconate Lactonizing
CS345_RS11980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS345_RS11990	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CS345_RS12010	COG4133	protoheme IX ABC transporter activity
CS345_RS12015	COG3005	denitrification pathway
CS345_RS12020	COG3043	anaerobic respiration
CS345_RS12040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS12045	COG0765	amino acid transport
CS345_RS12050	COG1126	abc transporter atp-binding protein
CS345_RS12055	COG0330	HflC and HflK could
CS345_RS12065	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS12065	COG1454	alcohol dehydrogenase
CS345_RS12070	COG3706	GGDEF domain
CS345_RS12070	COG2203	Gaf domain
CS345_RS12070	COG4251	negative regulation of phosphorylation
CS345_RS12070	COG5001	Diguanylate cyclase
CS345_RS12080	COG0583	DNA-binding transcription factor activity
CS345_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS12115	COG0431	NADPH-dependent FMN reductase
CS345_RS12120	COG0583	DNA-binding transcription factor activity
CS345_RS12140	COG0824	Thioesterase
CS345_RS12145	COG1454	alcohol dehydrogenase
CS345_RS12150	COG0183	Belongs to the thiolase family
CS345_RS12155	COG1024	Enoyl-CoA hydratase
CS345_RS12155	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS12160	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS12170	COG1024	Enoyl-CoA hydratase
CS345_RS12175	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS12180	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS12185	COG0583	DNA-binding transcription factor activity
CS345_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS12205	COG0183	Belongs to the thiolase family
CS345_RS12210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS12215	COG1414	Transcriptional regulator
CS345_RS12225	COG3119	arylsulfatase activity
CS345_RS12240	COG0625	glutathione transferase activity
CS345_RS12245	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CS345_RS12250	COG2944	sequence-specific DNA binding
CS345_RS12260	COG2197	response regulator
CS345_RS12280	COG3119	arylsulfatase activity
CS345_RS12315	COG0714	Associated with various cellular activities
CS345_RS12320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS345_RS12335	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS12340	COG0861	Integral membrane protein TerC family
CS345_RS12370	COG1228	amidohydrolase
CS345_RS12380	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS345_RS12390	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS345_RS12410	COG0583	DNA-binding transcription factor activity
CS345_RS12415	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS12440	COG2188	Transcriptional regulator
CS345_RS12450	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS12455	COG1414	Transcriptional regulator
CS345_RS12460	COG3842	ATPase activity
CS345_RS12470	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS345_RS12475	COG0395	ABC-type sugar transport system, permease component
CS345_RS12490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS12510	COG0439	Biotin carboxylase
CS345_RS12515	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CS345_RS12520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS12535	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS12545	COG0583	DNA-binding transcription factor activity
CS345_RS12555	COG2814	Major facilitator Superfamily
CS345_RS12570	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS345_RS12585	COG2084	Dehydrogenase
CS345_RS12600	COG1253	flavin adenine dinucleotide binding
CS345_RS12615	COG2988	succinylglutamate desuccinylase activity
CS345_RS12640	COG0861	Integral membrane protein TerC family
CS345_RS12650	COG1595	DNA-templated transcription, initiation
CS345_RS12665	COG0076	glutamate decarboxylase activity
CS345_RS12670	COG2985	domain, Protein
CS345_RS12680	COG3189	MarR family transcriptional regulator
CS345_RS12690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS12700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS12700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS12710	COG0028	Belongs to the TPP enzyme family
CS345_RS12720	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS12725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS345_RS12730	COG0010	Belongs to the arginase family
CS345_RS12735	COG1126	abc transporter atp-binding protein
CS345_RS12740	COG0765	amino acid transport
CS345_RS12745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS12760	COG0084	hydrolase, TatD family'
CS345_RS12765	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS345_RS12770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS345_RS12775	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CS345_RS12800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS12800	COG1024	Enoyl-CoA hydratase
CS345_RS12805	COG1960	acyl-CoA dehydrogenase activity
CS345_RS12815	COG2867	negative regulation of translational initiation
CS345_RS12820	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CS345_RS12825	COG3706	GGDEF domain
CS345_RS12830	COG0330	HflC and HflK could
CS345_RS12840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS345_RS12840	COG0519	Catalyzes the synthesis of GMP from XMP
CS345_RS12855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS345_RS12860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CS345_RS12875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CS345_RS12880	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS345_RS12885	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CS345_RS12890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS345_RS12895	COG0750	zinc metalloprotease
CS345_RS12900	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CS345_RS12905	COG0575	Belongs to the CDS family
CS345_RS12910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CS345_RS12915	COG0233	cytoplasmic translational termination
CS345_RS12920	COG0528	UMP kinase activity
CS345_RS12925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CS345_RS12930	COG0052	Belongs to the universal ribosomal protein uS2 family
CS345_RS12935	COG0024	Methionine aminopeptidase
CS345_RS12940	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CS345_RS12970	COG0285	dihydrofolate synthase activity
CS345_RS13000	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CS345_RS13010	COG1677	Flagellar hook-basal body complex protein FliE
CS345_RS13020	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS345_RS13030	COG1157	protein secretion by the type III secretion system
CS345_RS13045	COG1580	Controls the rotational direction of flagella during chemotaxis
CS345_RS13055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS345_RS13065	COG1338	Plays a role in the flagellum-specific transport system
CS345_RS13080	COG0840	transmembrane signaling receptor activity
CS345_RS13085	COG0840	transmembrane signaling receptor activity
CS345_RS13095	COG0840	transmembrane signaling receptor activity
CS345_RS13100	COG0840	transmembrane signaling receptor activity
CS345_RS13110	COG1256	bacterial-type flagellum assembly
CS345_RS13125	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CS345_RS13140	COG1749	Flagellar hook protein flgE
CS345_RS13150	COG1558	bacterial-type flagellum-dependent cell motility
CS345_RS13155	COG1815	bacterial-type flagellum-dependent cell motility
CS345_RS13190	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CS345_RS13195	COG0745	RESPONSE REGULATOR receiver
CS345_RS13200	COG2201	protein-glutamate methylesterase activity
CS345_RS13205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CS345_RS13210	COG0840	transmembrane signaling receptor activity
CS345_RS13220	COG2198	Histidine kinase
CS345_RS13220	COG0643	Histidine kinase
CS345_RS13225	COG0745	RESPONSE REGULATOR receiver
CS345_RS13255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CS345_RS13260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS345_RS13265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS345_RS13270	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CS345_RS13280	COG4566	intracellular signal transduction
CS345_RS13285	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS345_RS13290	COG0339	signal peptide processing
CS345_RS13295	COG1999	signal sequence binding
CS345_RS13315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS345_RS13325	COG1187	pseudouridine synthase activity
CS345_RS13330	COG3161	chorismate lyase activity
CS345_RS13335	COG2814	Major facilitator Superfamily
CS345_RS13345	COG1280	lysine exporter protein (LysE YggA)
CS345_RS13350	COG4172	Belongs to the ABC transporter superfamily
CS345_RS13355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS13360	COG0601	transmembrane transport
CS345_RS13365	COG0747	negative chemotaxis
CS345_RS13410	COG0668	transmembrane transport
CS345_RS13415	COG0165	Argininosuccinate lyase
CS345_RS13425	COG0789	Transcriptional regulator
CS345_RS13435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS13440	COG0765	amino acid transport
CS345_RS13445	COG1126	abc transporter atp-binding protein
CS345_RS13455	COG2346	COG2346, Truncated hemoglobins
CS345_RS13515	COG1335	isochorismatase
CS345_RS13520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS13540	COG2837	iron assimilation
CS345_RS13570	COG4691	Plasmid stability protein
CS345_RS13610	COG2814	Major facilitator Superfamily
CS345_RS13620	COG0501	Belongs to the peptidase M48B family
CS345_RS13630	COG0583	DNA-binding transcription factor activity
CS345_RS13640	COG2188	Transcriptional regulator
CS345_RS13655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS345_RS13665	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS13670	COG0129	dihydroxy-acid dehydratase activity
CS345_RS13685	COG0129	dihydroxy-acid dehydratase activity
CS345_RS13695	COG3622	Belongs to the hyi family
CS345_RS13700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS345_RS13705	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS13720	COG0583	DNA-binding transcription factor activity
CS345_RS13725	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS13730	COG3246	L-lysine catabolic process to acetate
CS345_RS13745	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CS345_RS13750	COG0534	Mate efflux family protein
CS345_RS13765	COG0697	spore germination
CS345_RS13780	COG0625	glutathione transferase activity
CS345_RS13800	COG1280	lysine exporter protein (LysE YggA)
CS345_RS13805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS345_RS13840	COG2207	Transcriptional regulator
CS345_RS13880	COG1132	(ABC) transporter
CS345_RS13905	COG0659	secondary active sulfate transmembrane transporter activity
CS345_RS13935	COG2169	Transcriptional regulator
CS345_RS13940	COG5507	3-demethylubiquinone-9 3-methyltransferase
CS345_RS13945	COG0384	phenazine biosynthesis protein PhzF
CS345_RS13950	COG0583	DNA-binding transcription factor activity
CS345_RS13955	COG2733	membrane
CS345_RS13970	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS13975	COG3284	Transcriptional regulator
CS345_RS13980	COG0656	L-ascorbic acid biosynthetic process
CS345_RS14000	COG1131	(ABC) transporter
CS345_RS14005	COG0842	Transport permease protein
CS345_RS14010	COG0842	Transport permease protein
CS345_RS14025	COG1802	Transcriptional regulator
CS345_RS14045	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS14050	COG2188	Transcriptional regulator
CS345_RS14075	COG0789	Transcriptional regulator
CS345_RS14090	COG1609	Transcriptional regulator
CS345_RS14095	COG4172	Belongs to the ABC transporter superfamily
CS345_RS14100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS14105	COG0601	transmembrane transport
CS345_RS14110	COG0747	negative chemotaxis
CS345_RS14125	COG1280	lysine exporter protein (LysE YggA)
CS345_RS14145	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CS345_RS14170	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS14175	COG2079	MmgE PrpD family protein
CS345_RS14200	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS14210	COG3618	amidohydrolase
CS345_RS14225	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CS345_RS14250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS14255	COG1116	anion transmembrane transporter activity
CS345_RS14265	COG1228	amidohydrolase
CS345_RS14270	COG1414	Transcriptional regulator
CS345_RS14280	COG0477	Major facilitator Superfamily
CS345_RS14300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS345_RS14300	COG0519	Catalyzes the synthesis of GMP from XMP
CS345_RS14320	COG2197	response regulator
CS345_RS14335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS345_RS14350	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS14370	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS345_RS14370	COG3064	Membrane
CS345_RS14370	COG3210	domain, Protein
CS345_RS14375	COG0047	phosphoribosylformylglycinamidine synthase activity
CS345_RS14375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CS345_RS14380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS14385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS14385	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS14390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS14400	COG0613	PHP domain protein
CS345_RS14410	COG0658	competence protein
CS345_RS14410	COG2333	competence protein COMEC
CS345_RS14420	COG0084	hydrolase, TatD family'
CS345_RS14425	COG1136	(ABC) transporter
CS345_RS14440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CS345_RS14450	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS14455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CS345_RS14470	COG1022	Amp-dependent synthetase and ligase
CS345_RS14500	COG1024	Enoyl-CoA hydratase
CS345_RS14515	COG0633	Ferredoxin
CS345_RS14520	COG0443	Heat shock 70 kDa protein
CS345_RS14525	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CS345_RS14530	COG0316	Belongs to the HesB IscA family
CS345_RS14535	COG0822	iron-sulfur transferase activity
CS345_RS14540	COG1104	cysteine desulfurase activity
CS345_RS14550	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS345_RS14555	COG0556	nucleotide-excision repair
CS345_RS14565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS345_RS14570	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS14580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS345_RS14595	COG1960	acyl-CoA dehydrogenase activity
CS345_RS14600	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS14605	COG0183	Belongs to the thiolase family
CS345_RS14615	COG1024	Enoyl-CoA hydratase
CS345_RS14630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS14635	COG0583	DNA-binding transcription factor activity
CS345_RS14640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS345_RS14650	COG0740	serine-type endopeptidase activity
CS345_RS14655	COG0544	peptidyl-prolyl cis-trans isomerase activity
CS345_RS14665	COG1278	Cold shock
CS345_RS14675	COG1278	Cold shock
CS345_RS14700	COG2135	peptidase activity
CS345_RS14775	COG1196	nuclear chromosome segregation
CS345_RS14955	COG3723	Recombinational DNA repair protein, rece pathway
CS345_RS15015	COG0582	viral genome integration into host DNA
CS345_RS15025	COG0436	Aminotransferase
CS345_RS15030	COG2171	N-acyltransferase activity
CS345_RS15035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS345_RS15040	COG2890	protein-(glutamine-N5) methyltransferase activity
CS345_RS15045	COG0488	(ABC) transporter
CS345_RS15050	COG4771	TonB-dependent receptor
CS345_RS15055	COG0210	DNA helicase
CS345_RS15070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS345_RS15070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS345_RS15075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CS345_RS15080	COG0196	riboflavin kinase activity
CS345_RS15085	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CS345_RS15090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CS345_RS15095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CS345_RS15105	COG1522	sequence-specific DNA binding
CS345_RS15115	COG0586	Pfam SNARE associated Golgi protein
CS345_RS15130	COG1126	abc transporter atp-binding protein
CS345_RS15135	COG0765	amino acid transport
CS345_RS15140	COG0765	amino acid transport
CS345_RS15145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS15155	COG2423	ornithine cyclodeaminase activity
CS345_RS15160	COG1764	response to oxidative stress
CS345_RS15170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS345_RS15175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS345_RS15190	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CS345_RS15195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CS345_RS15200	COG2197	response regulator
CS345_RS15210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS345_RS15255	COG0135	phosphoribosylanthranilate isomerase activity
CS345_RS15270	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS15285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS345_RS15310	COG1122	ATPase activity
CS345_RS15340	COG0437	4 iron, 4 sulfur cluster binding
CS345_RS15345	COG0243	molybdopterin cofactor binding
CS345_RS15345	COG3383	formate dehydrogenase (NAD+) activity
CS345_RS15375	COG0489	protein tyrosine kinase activity
CS345_RS15380	COG0746	molybdenum cofactor guanylyltransferase activity
CS345_RS15385	COG0303	'Molybdopterin
CS345_RS15390	COG1763	Mo-molybdopterin cofactor biosynthetic process
CS345_RS15400	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CS345_RS15405	COG3300	MHYT domain
CS345_RS15405	COG5001	Diguanylate cyclase
CS345_RS15410	COG2205	protein histidine kinase activity
CS345_RS15415	COG0745	RESPONSE REGULATOR receiver
CS345_RS15430	COG1295	ribonuclease BN
CS345_RS15440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS345_RS15475	COG4964	Belongs to the GSP D family
CS345_RS15540	COG0861	Integral membrane protein TerC family
CS345_RS15545	COG0861	Integral membrane protein TerC family
CS345_RS15550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS345_RS15555	COG0045	succinate-CoA ligase (ADP-forming) activity
CS345_RS15575	COG2137	regulation of response to DNA damage stimulus
CS345_RS15580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CS345_RS15600	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS15600	COG1024	Enoyl-CoA hydratase
CS345_RS15605	COG3842	ATPase activity
CS345_RS15620	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS15640	COG0583	DNA-binding transcription factor activity
CS345_RS15645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS15655	COG2974	May be involved in recombination
CS345_RS15660	COG0540	Belongs to the ATCase OTCase family
CS345_RS15700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS15715	COG1522	sequence-specific DNA binding
CS345_RS15725	COG2367	Beta-lactamase
CS345_RS15740	COG0500	methyltransferase
CS345_RS15775	COG0072	phenylalanine-tRNA ligase activity
CS345_RS15775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS345_RS15780	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CS345_RS15785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CS345_RS15790	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CS345_RS15815	COG0004	ammonium transporteR
CS345_RS15820	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS15825	COG1309	transcriptional regulator
CS345_RS15830	COG2271	Major facilitator Superfamily
CS345_RS15860	COG0506	proline dehydrogenase activity
CS345_RS15860	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS345_RS15860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS345_RS15870	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS345_RS15870	COG3008	intermembrane lipid transfer
CS345_RS15875	COG2995	paraquat-inducible protein a
CS345_RS15880	COG0542	response to heat
CS345_RS15885	COG4953	penicillin-binding protein 1C
CS345_RS15895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CS345_RS15900	COG1278	Cold shock
CS345_RS15910	COG0183	Belongs to the thiolase family
CS345_RS15915	COG0038	chloride channel
CS345_RS15920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS345_RS15930	COG0811	peptide transport
CS345_RS15935	COG0848	biopolymer transport protein
CS345_RS15945	COG2835	tetraacyldisaccharide 4'-kinase activity
CS345_RS15955	COG0563	adenylate kinase activity
CS345_RS15965	COG0728	peptidoglycan biosynthetic process
CS345_RS15975	COG0268	Binds directly to 16S ribosomal RNA
CS345_RS15995	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS345_RS16000	COG2186	Transcriptional regulator
CS345_RS16015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS345_RS16025	COG0583	DNA-binding transcription factor activity
CS345_RS16035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS345_RS16040	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CS345_RS16045	COG0137	argininosuccinate synthase activity
CS345_RS16050	COG3158	transport of potassium into the cell
CS345_RS16055	COG0642	Histidine kinase
CS345_RS16090	COG0776	regulation of translation
CS345_RS16095	COG3128	pkhd-type hydroxylase
CS345_RS16105	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS345_RS16110	COG0557	exoribonuclease II activity
CS345_RS16135	COG0679	Auxin Efflux Carrier
CS345_RS16140	COG2391	methyltransferase activity
CS345_RS16145	COG0069	glutamate synthase activity
CS345_RS16150	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS345_RS16160	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CS345_RS16165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS345_RS16200	COG3706	GGDEF domain
CS345_RS16230	COG3909	cytochrome
CS345_RS16235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CS345_RS16240	COG0625	glutathione transferase activity
CS345_RS16245	COG0730	response to heat
CS345_RS16250	COG0482	sulfurtransferase activity
CS345_RS16255	COG0583	DNA-binding transcription factor activity
CS345_RS16295	COG2819	hydrolase of the alpha beta superfamily
CS345_RS16300	COG0247	lactate metabolic process
CS345_RS16305	COG0277	FAD linked oxidase domain protein
CS345_RS16310	COG0277	FAD linked oxidase domain protein
CS345_RS16315	COG0277	FAD linked oxidase domain protein
CS345_RS16320	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS345_RS16320	COG3210	domain, Protein
CS345_RS16320	COG3064	Membrane
CS345_RS16320	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS345_RS16320	COG3210	domain, Protein
CS345_RS16320	COG3064	Membrane
CS345_RS16325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS345_RS16330	COG0312	modulator of DNA gyrase
CS345_RS16350	COG0308	aminopeptidase N
CS345_RS16355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CS345_RS16375	COG0436	Aminotransferase
CS345_RS16380	COG3737	Protein of unknown function (DUF498/DUF598)
CS345_RS16385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS345_RS16390	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CS345_RS16395	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS345_RS16405	COG0305	Participates in initiation and elongation during chromosome replication
CS345_RS16420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CS345_RS16425	COG2965	DNA replication, synthesis of RNA primer
CS345_RS16430	COG0360	Binds together with S18 to 16S ribosomal RNA
CS345_RS16435	COG1469	GTP cyclohydrolase I activity
CS345_RS16445	COG0142	geranyltranstransferase activity
CS345_RS16450	COG1722	exodeoxyribonuclease VII activity
CS345_RS16460	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS16495	COG1840	ABC-type Fe3 transport system, periplasmic component
CS345_RS16500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS345_RS16505	COG1178	ABC-type Fe3 transport system permease component
CS345_RS16510	COG3842	ATPase activity
CS345_RS16515	COG0583	DNA-binding transcription factor activity
CS345_RS16535	COG0501	Belongs to the peptidase M48B family
CS345_RS16545	COG0697	spore germination
CS345_RS16555	COG1846	Transcriptional regulator
CS345_RS16565	COG1566	PFAM secretion protein HlyD family protein
CS345_RS16570	COG2814	Major facilitator Superfamily
CS345_RS16575	COG0473	3-isopropylmalate dehydrogenase activity
CS345_RS16585	COG0747	negative chemotaxis
CS345_RS16595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS16605	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS345_RS16630	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS16640	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS345_RS16645	COG0433	COG0433 Predicted ATPase
CS345_RS16655	COG0151	Belongs to the GarS family
CS345_RS16665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CS345_RS16670	COG0799	negative regulation of ribosome biogenesis
CS345_RS16675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CS345_RS16685	COG3468	outer membrane autotransporter barrel domain protein
CS345_RS16715	COG1530	ribonuclease E activity
CS345_RS16720	COG0077	Prephenate dehydratase
CS345_RS16735	COG1132	(ABC) transporter
CS345_RS16740	COG0859	PFAM glycosyl transferase family 9
CS345_RS16765	COG2194	sulfuric ester hydrolase activity
CS345_RS16770	COG0438	transferase activity, transferring glycosyl groups
CS345_RS16775	COG0463	Glycosyl transferase, family 2
CS345_RS16780	COG0726	polysaccharide deacetylase
CS345_RS16785	COG0438	transferase activity, transferring glycosyl groups
CS345_RS16800	COG1643	Atp-dependent helicase
CS345_RS16805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS345_RS16805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CS345_RS16810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CS345_RS16820	COG0704	Plays a role in the regulation of phosphate uptake
CS345_RS16830	COG1960	acyl-CoA dehydrogenase activity
CS345_RS16845	COG2094	Belongs to the DNA glycosylase MPG family
CS345_RS16855	COG1177	transmembrane transport
CS345_RS16860	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS345_RS16865	COG3842	ATPase activity
CS345_RS16870	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CS345_RS16885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CS345_RS16900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS345_RS16900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS345_RS16905	COG3539	Fimbrial protein
CS345_RS16910	COG3539	Fimbrial protein
CS345_RS16915	COG3539	Fimbrial protein
CS345_RS16920	COG3539	Fimbrial protein
CS345_RS16925	COG3539	Fimbrial protein
CS345_RS16935	COG2050	protein possibly involved in aromatic compounds catabolism
CS345_RS16940	COG1024	Enoyl-CoA hydratase
CS345_RS16945	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS16950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS345_RS16955	COG2151	metal-sulfur cluster biosynthetic enzyme
CS345_RS16960	COG3396	Phenylacetate-CoA oxygenase
CS345_RS16965	COG3460	Phenylacetate-CoA oxygenase
CS345_RS16970	COG3396	Phenylacetate-CoA oxygenase
CS345_RS16975	COG3327	negative regulation of DNA-templated transcription, initiation
CS345_RS16985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CS345_RS16990	COG0501	Belongs to the peptidase M48B family
CS345_RS16995	COG1162	GTPase activity
CS345_RS17000	COG0667	Aldo Keto reductase
CS345_RS17010	COG0335	large ribosomal subunit rRNA binding
CS345_RS17040	COG0175	sulfate reduction
CS345_RS17045	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS345_RS17050	COG4208	sulfate ABC transporter
CS345_RS17065	COG0450	alkyl hydroperoxide reductase
CS345_RS17070	COG1960	acyl-CoA dehydrogenase activity
CS345_RS17085	COG0123	including yeast histone deacetylase and acetoin utilization protein
CS345_RS17090	COG2951	lytic endotransglycosylase activity
CS345_RS17100	COG1555	photosystem II stabilization
CS345_RS17100	COG1596	polysaccharide export
CS345_RS17110	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CS345_RS17115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CS345_RS17135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CS345_RS17140	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CS345_RS17145	COG0287	Prephenate dehydrogenase
CS345_RS17170	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CS345_RS17180	COG2814	Major facilitator Superfamily
CS345_RS17190	COG2135	peptidase activity
CS345_RS17460	COG0582	viral genome integration into host DNA
CS345_RS17465	COG0583	DNA-binding transcription factor activity
CS345_RS17505	COG0583	DNA-binding transcription factor activity
CS345_RS17520	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS345_RS17545	COG1053	succinate dehydrogenase
CS345_RS17550	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS17555	COG2079	MmgE PrpD family protein
CS345_RS17565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS17580	COG0583	DNA-binding transcription factor activity
CS345_RS17590	COG0028	Belongs to the TPP enzyme family
CS345_RS17590	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
CS345_RS17595	COG0436	Aminotransferase
CS345_RS17615	COG0778	Nitroreductase
CS345_RS17620	COG2814	Major facilitator Superfamily
CS345_RS17625	COG3706	GGDEF domain
CS345_RS17630	COG0589	response to stress
CS345_RS17640	COG2951	lytic endotransglycosylase activity
CS345_RS17645	COG2833	Protein of unknown function (DUF455)
CS345_RS17660	COG1132	(ABC) transporter
CS345_RS17665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS345_RS17665	COG0189	ligase activity
CS345_RS17670	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS345_RS17670	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS345_RS17675	COG3237	CsbD-like
CS345_RS17685	COG2823	Periplasmic or secreted lipoprotein
CS345_RS17700	COG0672	)-iron permease
CS345_RS17715	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CS345_RS17720	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS17725	COG3243	poly(R)-hydroxyalkanoic acid synthase
CS345_RS17735	COG0564	pseudouridine synthase activity
CS345_RS17745	COG1199	ATP-dependent helicase activity
CS345_RS17750	COG2183	response to ionizing radiation
CS345_RS17775	COG4774	siderophore transport
CS345_RS17780	COG3712	iron ion homeostasis
CS345_RS17785	COG1595	DNA-templated transcription, initiation
CS345_RS17790	COG2175	clavaminate synthase activity
CS345_RS17800	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS17805	COG0583	DNA-binding transcription factor activity
CS345_RS17810	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS17815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CS345_RS17820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS345_RS17825	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS345_RS17830	COG0567	Dehydrogenase, E1 component
CS345_RS17835	COG1297	OPT oligopeptide transporter protein
CS345_RS17840	COG1522	sequence-specific DNA binding
CS345_RS17850	COG0280	phosphate acetyltransferase
CS345_RS17850	COG0281	malic enzyme
CS345_RS17855	COG3539	Fimbrial protein
CS345_RS17870	COG0372	Belongs to the citrate synthase family
CS345_RS17875	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CS345_RS17880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CS345_RS17885	COG1053	succinate dehydrogenase
CS345_RS17890	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CS345_RS17895	COG2009	succinate dehydrogenase
CS345_RS17900	COG2188	Transcriptional regulator
CS345_RS17905	COG0039	L-malate dehydrogenase activity
CS345_RS17925	COG2828	Protein conserved in bacteria
CS345_RS17930	COG2079	MmgE PrpD family protein
CS345_RS17935	COG1981	membrane
CS345_RS17960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS345_RS17970	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CS345_RS18000	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CS345_RS18005	COG0148	phosphopyruvate hydratase activity
CS345_RS18015	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CS345_RS18020	COG0504	CTP synthase activity
CS345_RS18040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS18050	COG0747	negative chemotaxis
CS345_RS18055	COG4172	Belongs to the ABC transporter superfamily
CS345_RS18060	COG1446	asparaginase
CS345_RS18105	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CS345_RS18110	COG0697	spore germination
CS345_RS18115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS345_RS18125	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CS345_RS18130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS345_RS18135	COG0791	NLP P60 protein
CS345_RS18145	COG0583	DNA-binding transcription factor activity
CS345_RS18160	COG0583	DNA-binding transcription factor activity
CS345_RS18170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CS345_RS18185	COG0670	Belongs to the BI1 family
CS345_RS18200	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CS345_RS18210	COG1381	Involved in DNA repair and RecF pathway recombination
CS345_RS18215	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CS345_RS18220	COG0571	ribonuclease III activity
CS345_RS18225	COG0681	Belongs to the peptidase S26 family
CS345_RS18235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS345_RS18260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS345_RS18265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CS345_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS18280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS345_RS18285	COG0416	fatty acid biosynthetic process
CS345_RS18290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CS345_RS18295	COG1399	metal-binding, possibly nucleic acid-binding protein
CS345_RS18300	COG0424	maF-like protein
CS345_RS18310	COG3023	N-Acetylmuramoyl-L-alanine amidase
CS345_RS18315	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CS345_RS18320	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CS345_RS18325	COG0546	phosphoglycolate phosphatase activity
CS345_RS18335	COG1530	ribonuclease E activity
CS345_RS18345	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CS345_RS18350	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CS345_RS18355	COG0159	tryptophan synthase activity
CS345_RS18370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS345_RS18375	COG3228	Belongs to the MtfA family
CS345_RS18385	COG0251	oxidation-reduction process
CS345_RS18390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CS345_RS18395	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CS345_RS18410	COG2878	Part of a membrane complex involved in electron transport
CS345_RS18415	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CS345_RS18450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS345_RS18475	COG1268	BioY protein
CS345_RS18480	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CS345_RS18485	COG1122	ATPase activity
CS345_RS18490	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS345_RS18500	COG0271	Belongs to the BolA IbaG family
CS345_RS18505	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS345_RS18510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CS345_RS18520	COG1196	nuclear chromosome segregation
CS345_RS18525	COG0477	Major facilitator Superfamily
CS345_RS18530	COG1573	uracil-dna glycosylase
CS345_RS18535	COG1214	PFAM Peptidase M22, glycoprotease
CS345_RS18550	COG0450	alkyl hydroperoxide reductase
CS345_RS18555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS18565	COG2223	nitrite transmembrane transporter activity
CS345_RS18570	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CS345_RS18575	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CS345_RS18580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CS345_RS18585	COG0560	Phosphoserine phosphatase
CS345_RS18590	COG0583	DNA-binding transcription factor activity
CS345_RS18595	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS18600	COG0028	Belongs to the TPP enzyme family
CS345_RS18615	COG4774	siderophore transport
CS345_RS18620	COG4774	siderophore transport
CS345_RS18630	COG1007	ATP synthesis coupled electron transport
CS345_RS18645	COG0713	ATP synthesis coupled electron transport
CS345_RS18655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS345_RS18660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CS345_RS18665	COG1034	ATP synthesis coupled electron transport
CS345_RS18675	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CS345_RS18685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS345_RS18690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS345_RS18695	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS345_RS18700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS345_RS18720	COG0671	phosphoesterase, PA-phosphatase related
CS345_RS18730	COG1597	lipid kinase activity
CS345_RS18735	COG0583	DNA-binding transcription factor activity
CS345_RS18740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS345_RS18745	COG1733	regulation of RNA biosynthetic process
CS345_RS18750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS345_RS18755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS345_RS18770	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CS345_RS18790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS18810	COG3608	succinylglutamate desuccinylase aspartoacylase
CS345_RS18815	COG0626	cystathionine gamma-synthase activity
CS345_RS18820	COG0583	DNA-binding transcription factor activity
CS345_RS18830	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS18835	COG0165	Argininosuccinate lyase
CS345_RS18850	COG3799	methylaspartate ammonia-lyase activity
CS345_RS18860	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS345_RS18870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS345_RS18875	COG0149	triose-phosphate isomerase activity
CS345_RS18895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS345_RS18905	COG1185	polyribonucleotide nucleotidyltransferase activity
CS345_RS18910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CS345_RS18925	COG1183	phosphatidylcholine synthase activity
CS345_RS18935	COG0440	acetolactate synthase activity
CS345_RS18940	COG0028	Belongs to the TPP enzyme family
CS345_RS18945	COG1289	transmembrane transporter activity
CS345_RS18955	COG3022	response to hydroperoxide
CS345_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS18975	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CS345_RS19005	COG2814	Major facilitator Superfamily
CS345_RS19025	COG3706	GGDEF domain
CS345_RS19055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CS345_RS19060	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CS345_RS19065	COG1674	ftsk spoiiie
CS345_RS19070	COG0492	ferredoxin-NADP+ reductase activity
CS345_RS19075	COG1193	negative regulation of DNA recombination
CS345_RS19085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CS345_RS19100	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CS345_RS19105	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CS345_RS19110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CS345_RS19115	COG2205	protein histidine kinase activity
CS345_RS19120	COG0745	RESPONSE REGULATOR receiver
CS345_RS19155	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS345_RS19175	COG0612	Peptidase, M16
CS345_RS19180	COG0484	heat shock protein binding
CS345_RS19185	COG0443	Heat shock 70 kDa protein
CS345_RS19195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CS345_RS19205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CS345_RS19210	COG1420	regulation of RNA biosynthetic process
CS345_RS19220	COG0497	DNA recombination
CS345_RS19225	COG0735	belongs to the Fur family
CS345_RS19230	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS345_RS19240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CS345_RS19260	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS19275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS345_RS19275	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS345_RS19280	COG4311	Sarcosine oxidase, delta subunit
CS345_RS19285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS19295	COG0583	DNA-binding transcription factor activity
CS345_RS19305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS345_RS19315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS19320	COG2030	dehydratase
CS345_RS19330	COG1024	Enoyl-CoA hydratase
CS345_RS19355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS345_RS19380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS345_RS19385	COG0730	response to heat
CS345_RS19395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS19405	COG0405	Gamma-glutamyltransferase
CS345_RS19420	COG1280	lysine exporter protein (LysE YggA)
CS345_RS19450	COG0583	DNA-binding transcription factor activity
CS345_RS19460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CS345_RS19465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CS345_RS19470	COG0167	dihydroorotate dehydrogenase activity
CS345_RS19490	COG1414	Transcriptional regulator
CS345_RS19495	COG1546	Belongs to the CinA family
CS345_RS19495	COG1058	Belongs to the CinA family
CS345_RS19510	COG0513	Belongs to the DEAD box helicase family
CS345_RS19545	COG0429	hydrolase of the alpha beta-hydrolase fold
CS345_RS19550	COG4783	chaperone-mediated protein folding
CS345_RS19565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS345_RS19580	COG0006	proline dipeptidase activity
CS345_RS19590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS345_RS19610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CS345_RS19615	COG0632	four-way junction helicase activity
CS345_RS19630	COG2255	four-way junction helicase activity
CS345_RS19635	COG0514	ATP-dependent DNA helicase (RecQ)
CS345_RS19660	COG1271	oxidase subunit
CS345_RS19665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS345_RS19670	COG0850	regulation of cytokinetic process
CS345_RS19675	COG2894	cell division
CS345_RS19680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CS345_RS19695	COG0488	(ABC) transporter
CS345_RS19720	COG4608	Belongs to the ABC transporter superfamily
CS345_RS19725	COG0444	Belongs to the ABC transporter superfamily
CS345_RS19730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS19735	COG0601	transmembrane transport
CS345_RS19740	COG0747	negative chemotaxis
CS345_RS19745	COG1215	transferase activity, transferring glycosyl groups
CS345_RS19750	COG0583	DNA-binding transcription factor activity
CS345_RS19760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CS345_RS19770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS345_RS19785	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS19790	COG2188	Transcriptional regulator
CS345_RS19795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CS345_RS19800	COG2814	Major facilitator Superfamily
CS345_RS19810	COG0259	pyridoxamine-phosphate oxidase activity
CS345_RS19815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS345_RS19830	COG0583	DNA-binding transcription factor activity
CS345_RS19835	COG1960	acyl-CoA dehydrogenase activity
CS345_RS19845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS19850	COG0405	Gamma-glutamyltransferase
CS345_RS19860	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS19875	COG0802	atpase or kinase
CS345_RS19880	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS345_RS19885	COG0586	Pfam SNARE associated Golgi protein
CS345_RS19890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CS345_RS19895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CS345_RS19900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CS345_RS19915	COG0617	tRNA 3'-terminal CCA addition
CS345_RS19940	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS19945	COG2188	Transcriptional regulator
CS345_RS19955	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS345_RS19960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS345_RS19965	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS19975	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS19980	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS19985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS345_RS19990	COG2301	Belongs to the HpcH HpaI aldolase family
CS345_RS19995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS20000	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CS345_RS20010	COG1024	Enoyl-CoA hydratase
CS345_RS20020	COG2188	Transcriptional regulator
CS345_RS20025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS345_RS20030	COG0066	3-isopropylmalate dehydratase activity
CS345_RS20045	COG0752	glycyl-tRNA synthetase alpha subunit
CS345_RS20050	COG0751	glycine-tRNA ligase activity
CS345_RS20055	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS345_RS20060	COG0204	Acyl-transferase
CS345_RS20075	COG0242	peptide deformylase activity
CS345_RS20080	COG1960	acyl-CoA dehydrogenase activity
CS345_RS20085	COG0700	Nucleoside recognition
CS345_RS20090	COG0469	pyruvate kinase activity
CS345_RS20095	COG1929	Belongs to the glycerate kinase type-1 family
CS345_RS20100	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CS345_RS20105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS345_RS20120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CS345_RS20130	COG2154	pterin-4-alpha-carbinolamine dehydratase
CS345_RS20150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS345_RS20155	COG0154	amidase activity
CS345_RS20165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS20170	COG0601	transmembrane transport
CS345_RS20175	COG0747	negative chemotaxis
CS345_RS20190	COG0019	diaminopimelate decarboxylase activity
CS345_RS20205	COG3712	iron ion homeostasis
CS345_RS20210	COG4774	siderophore transport
CS345_RS20215	COG2353	YceI-like domain
CS345_RS20220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS345_RS20235	COG0583	DNA-binding transcription factor activity
CS345_RS20255	COG3384	dioxygenase
CS345_RS20260	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS345_RS20295	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS20300	COG1309	transcriptional regulator
CS345_RS20305	COG2982	Protein involved in outer membrane biogenesis
CS345_RS20310	COG2818	Glycosylase
CS345_RS20330	COG1653	transport
CS345_RS20335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS345_RS20340	COG3842	ATPase activity
CS345_RS20345	COG0395	ABC-type sugar transport system, permease component
CS345_RS20350	COG1175	transmembrane transport
CS345_RS20365	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS20370	COG2186	Transcriptional regulator
CS345_RS20390	COG1454	alcohol dehydrogenase
CS345_RS20405	COG2011	ABC-type metal ion transport system permease component
CS345_RS20410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS345_RS20415	COG1501	Belongs to the glycosyl hydrolase 31 family
CS345_RS20420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS20420	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CS345_RS20430	COG0318	PFAM AMP-dependent synthetase and ligase
CS345_RS20435	COG1473	amidohydrolase
CS345_RS20445	COG2855	membrane
CS345_RS20455	COG2239	Acts as a magnesium transporter
CS345_RS20470	COG1522	sequence-specific DNA binding
CS345_RS20475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS20490	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS20500	COG0653	protein targeting
CS345_RS20505	COG0739	heme binding
CS345_RS20515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CS345_RS20520	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CS345_RS20530	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CS345_RS20535	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS345_RS20545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CS345_RS20555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CS345_RS20560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS345_RS20565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS345_RS20575	COG3116	cell division
CS345_RS20580	COG0275	rRNA processing
CS345_RS20585	COG2001	Belongs to the MraZ family
CS345_RS20595	COG0488	(ABC) transporter
CS345_RS20600	COG0418	dihydroorotase activity
CS345_RS20605	COG1473	amidohydrolase
CS345_RS20655	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS345_RS20660	COG4654	Cytochrome c, class I
CS345_RS20665	COG0129	dihydroxy-acid dehydratase activity
CS345_RS20670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CS345_RS20710	COG2084	Dehydrogenase
CS345_RS20715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CS345_RS20745	COG0494	nUDIX hydrolase
CS345_RS20750	COG0442	prolyl-tRNA aminoacylation
CS345_RS20755	COG0824	Thioesterase
CS345_RS20760	COG0811	peptide transport
CS345_RS20765	COG0848	biopolymer transport protein
CS345_RS20775	COG0823	Involved in the tonB-independent uptake of proteins
CS345_RS20790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS345_RS20795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CS345_RS20800	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS20815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS345_RS20840	COG0183	Belongs to the thiolase family
CS345_RS20850	COG1960	acyl-CoA dehydrogenase activity
CS345_RS20855	COG0583	DNA-binding transcription factor activity
CS345_RS20860	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS20865	COG1024	Enoyl-CoA hydratase
CS345_RS20870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS20875	COG1253	flavin adenine dinucleotide binding
CS345_RS20880	COG1285	pathogenesis
CS345_RS20885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS345_RS20900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS345_RS20905	COG0697	spore germination
CS345_RS20935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CS345_RS20940	COG0463	Glycosyl transferase, family 2
CS345_RS20950	COG0786	glutamate:sodium symporter activity
CS345_RS20960	COG2031	fatty acid transporter
CS345_RS20975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS345_RS20980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS345_RS20985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS345_RS20990	COG0328	RNA-DNA hybrid ribonuclease activity
CS345_RS20995	COG2226	methyltransferase
CS345_RS21000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS345_RS21005	COG0741	lytic transglycosylase activity
CS345_RS21005	COG1388	LysM domain
CS345_RS21020	COG2979	Protein of unknown function (DUF533)
CS345_RS21100	COG2816	NAD+ diphosphatase activity
CS345_RS21105	COG1309	transcriptional regulator
CS345_RS21110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS21125	COG1024	Enoyl-CoA hydratase
CS345_RS21140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS21155	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS21170	COG3119	arylsulfatase activity
CS345_RS21195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CS345_RS21210	COG0804	urea catabolic process
CS345_RS21215	COG0832	Belongs to the urease beta subunit family
CS345_RS21225	COG0831	urea catabolic process
CS345_RS21230	COG0829	nickel cation binding
CS345_RS21240	COG0633	Ferredoxin
CS345_RS21255	COG2188	Transcriptional regulator
CS345_RS21260	COG3799	methylaspartate ammonia-lyase activity
CS345_RS21280	COG2719	SpoVR family
CS345_RS21285	COG2718	Belongs to the UPF0229 family
CS345_RS21290	COG2766	serine protein kinase
CS345_RS21295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS345_RS21295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS345_RS21305	COG4977	sequence-specific DNA binding
CS345_RS21310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CS345_RS21315	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CS345_RS21325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CS345_RS21340	COG0316	Belongs to the HesB IscA family
CS345_RS21355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS345_RS21360	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CS345_RS21365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS345_RS21370	COG0312	modulator of DNA gyrase
CS345_RS21390	COG1116	anion transmembrane transporter activity
CS345_RS21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS21400	COG1335	isochorismatase
CS345_RS21405	COG0346	lactoylglutathione lyase activity
CS345_RS21410	COG0513	Belongs to the DEAD box helicase family
CS345_RS21415	COG3069	C4-dicarboxylate transmembrane transporter activity
CS345_RS21420	COG1802	Transcriptional regulator
CS345_RS21425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS345_RS21425	COG0045	succinate-CoA ligase (ADP-forming) activity
CS345_RS21425	COG1042	CoA-binding domain protein
CS345_RS21430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS345_RS21445	COG1522	sequence-specific DNA binding
CS345_RS21475	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS345_RS21480	COG1696	Membrane protein involved in D-alanine export
CS345_RS21505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS345_RS21515	COG2264	protein methyltransferase activity
CS345_RS21520	COG0439	Biotin carboxylase
CS345_RS21525	COG0511	ligase activity, forming carbon-carbon bonds
CS345_RS21530	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS345_RS21535	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS345_RS21540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS345_RS21545	COG3150	esterase
CS345_RS21550	COG0557	exoribonuclease II activity
CS345_RS21560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CS345_RS21565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CS345_RS21590	COG0540	Belongs to the ATCase OTCase family
CS345_RS21600	COG1678	Uncharacterized ACR, COG1678
CS345_RS21615	COG0352	thiamine-phosphate diphosphorylase activity
CS345_RS21620	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CS345_RS21645	COG1960	acyl-CoA dehydrogenase activity
CS345_RS21650	COG1024	Enoyl-CoA hydratase
CS345_RS21655	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS21715	COG0494	nUDIX hydrolase
CS345_RS21740	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CS345_RS21750	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CS345_RS21765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CS345_RS21770	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CS345_RS21780	COG0477	Major facilitator Superfamily
CS345_RS21800	COG1126	abc transporter atp-binding protein
CS345_RS21805	COG0765	amino acid transport
CS345_RS21810	COG4597	amino acid ABC transporter
CS345_RS21815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS21820	COG2884	Cell division ATP-binding protein ftsE
CS345_RS21825	COG2177	Part of the ABC transporter FtsEX involved in
CS345_RS21830	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CS345_RS21840	COG1194	a g-specific adenine glycosylase
CS345_RS21850	COG2226	methyltransferase
CS345_RS21860	COG4206	TonB-dependent receptor
CS345_RS21865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS345_RS21870	COG2022	thiamine diphosphate biosynthetic process
CS345_RS21875	COG0351	phosphomethylpyrimidine kinase
CS345_RS21880	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CS345_RS21890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CS345_RS21900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CS345_RS21915	COG2226	methyltransferase
CS345_RS21920	COG0745	RESPONSE REGULATOR receiver
CS345_RS21925	COG5002	protein histidine kinase activity
CS345_RS21935	COG5002	protein histidine kinase activity
CS345_RS21945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS345_RS21950	COG0583	DNA-binding transcription factor activity
CS345_RS21960	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS345_RS21965	COG1984	allophanate hydrolase subunit 2
CS345_RS21980	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS21990	COG1024	Enoyl-CoA hydratase
CS345_RS21995	COG0657	acetylesterase activity
CS345_RS22005	COG1802	Transcriptional regulator
CS345_RS22015	COG1238	metal cluster binding
CS345_RS22020	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS345_RS22025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS345_RS22045	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CS345_RS22050	COG4988	ABC transporter
CS345_RS22060	COG1294	oxidase, subunit
CS345_RS22075	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CS345_RS22085	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CS345_RS22100	COG1137	ATPase activity
CS345_RS22105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CS345_RS22120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CS345_RS22120	COG2010	Cytochrome c
CS345_RS22130	COG1660	Displays ATPase and GTPase activities
CS345_RS22140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS345_RS22155	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CS345_RS22160	COG2823	Periplasmic or secreted lipoprotein
CS345_RS22175	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS345_RS22185	COG1309	transcriptional regulator
CS345_RS22190	COG0471	metal ion transport
CS345_RS22195	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS345_RS22200	COG0772	Belongs to the SEDS family
CS345_RS22205	COG0768	penicillin binding
CS345_RS22215	COG1792	Involved in formation and maintenance of cell shape
CS345_RS22220	COG1077	Cell shape determining protein MreB Mrl
CS345_RS22225	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS345_RS22235	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS345_RS22240	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CS345_RS22245	COG0708	Exodeoxyribonuclease III
CS345_RS22250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS345_RS22255	COG2860	membrane
CS345_RS22265	COG0583	DNA-binding transcription factor activity
CS345_RS22270	COG0473	3-isopropylmalate dehydrogenase activity
CS345_RS22275	COG3391	amine dehydrogenase activity
CS345_RS22295	COG0583	DNA-binding transcription factor activity
CS345_RS22300	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CS345_RS22305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS345_RS22310	COG0765	amino acid transport
CS345_RS22315	COG0765	amino acid transport
CS345_RS22320	COG1126	abc transporter atp-binding protein
CS345_RS22325	COG1794	racemase activity, acting on amino acids and derivatives
CS345_RS22330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS345_RS22335	COG2223	nitrite transmembrane transporter activity
CS345_RS22340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS345_RS22340	COG2813	Specifically methylates the guanine in position
CS345_RS22350	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS345_RS22375	COG2918	glutathione biosynthetic process
CS345_RS22395	COG0583	DNA-binding transcription factor activity
CS345_RS22400	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CS345_RS22405	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS345_RS22440	COG0154	amidase activity
CS345_RS22450	COG1414	Transcriptional regulator
CS345_RS22470	COG2132	Multicopper oxidase
CS345_RS22490	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS345_RS22515	COG1024	Enoyl-CoA hydratase
CS345_RS22520	COG1024	Enoyl-CoA hydratase
CS345_RS22525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CS345_RS22535	COG0747	negative chemotaxis
CS345_RS22545	COG0601	transmembrane transport
CS345_RS22550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS22555	COG0444	Belongs to the ABC transporter superfamily
CS345_RS22560	COG4608	Belongs to the ABC transporter superfamily
CS345_RS22570	COG2195	Cleaves the N-terminal amino acid of tripeptides
CS345_RS22575	COG0210	DNA helicase
CS345_RS22580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CS345_RS22585	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CS345_RS22595	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CS345_RS22605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CS345_RS22615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CS345_RS22620	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CS345_RS22630	COG0356	it plays a direct role in the translocation of protons across the membrane
CS345_RS22645	COG1024	Enoyl-CoA hydratase
CS345_RS22665	COG0037	tRNA processing
CS345_RS22670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS345_RS22680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS345_RS22685	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CS345_RS22690	COG2967	ApaG domain
CS345_RS22695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS345_RS22700	COG0546	phosphoglycolate phosphatase activity
CS345_RS22710	COG0512	Glutamine amidotransferase of anthranilate synthase
CS345_RS22725	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS22745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS345_RS22755	COG1607	acyl-coa hydrolase
CS345_RS22800	COG3069	C4-dicarboxylate transmembrane transporter activity
CS345_RS22810	COG1802	Transcriptional regulator
CS345_RS22840	COG1595	DNA-templated transcription, initiation
CS345_RS22845	COG3712	iron ion homeostasis
CS345_RS22855	COG3720	iron ion transport
CS345_RS22860	COG4558	Periplasmic binding protein
CS345_RS22865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS345_RS22870	COG1120	ATPase activity
CS345_RS22875	COG1683	Conserved Protein
CS345_RS22905	COG3064	Membrane
CS345_RS22910	COG0583	DNA-binding transcription factor activity
CS345_RS22920	COG1234	tRNA 3'-trailer cleavage
CS345_RS22930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CS345_RS22935	COG1802	Transcriptional regulator
CS345_RS22945	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS345_RS22965	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS22985	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS23000	COG2186	Transcriptional regulator
CS345_RS23005	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS23010	COG4948	Mandelate Racemase Muconate Lactonizing
CS345_RS23030	COG1053	succinate dehydrogenase
CS345_RS23050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS345_RS23060	COG0411	ABC transporter
CS345_RS23065	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS345_RS23090	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS345_RS23095	COG1024	Enoyl-CoA hydratase
CS345_RS23100	COG0022	dehydrogenase e1 component
CS345_RS23105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CS345_RS23130	COG1960	acyl-CoA dehydrogenase activity
CS345_RS23135	COG1024	Enoyl-CoA hydratase
CS345_RS23140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS345_RS23160	COG1960	acyl-CoA dehydrogenase activity
CS345_RS23165	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS23170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS345_RS23195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS345_RS23200	COG1984	allophanate hydrolase subunit 2
CS345_RS23205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CS345_RS23210	COG0747	negative chemotaxis
CS345_RS23215	COG0601	transmembrane transport
CS345_RS23220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS23250	COG0511	ligase activity, forming carbon-carbon bonds
CS345_RS23255	COG0439	Biotin carboxylase
CS345_RS23270	COG0709	Synthesizes selenophosphate from selenide and ATP
CS345_RS23275	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CS345_RS23310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23320	COG0604	alcohol dehydrogenase
CS345_RS23330	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS23340	COG1960	acyl-CoA dehydrogenase activity
CS345_RS23345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23350	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS23355	COG1024	Enoyl-CoA hydratase
CS345_RS23360	COG0446	pyridine nucleotide-disulphide oxidoreductase
CS345_RS23360	COG1902	pentaerythritol trinitrate reductase activity
CS345_RS23365	COG1024	Enoyl-CoA hydratase
CS345_RS23370	COG1846	Transcriptional regulator
CS345_RS23390	COG4771	TonB-dependent receptor
CS345_RS23405	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS23410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23415	COG0183	Belongs to the thiolase family
CS345_RS23420	COG2030	dehydratase
CS345_RS23425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23465	COG3842	ATPase activity
CS345_RS23475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS345_RS23485	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CS345_RS23490	COG0583	DNA-binding transcription factor activity
CS345_RS23500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS345_RS23505	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS23515	COG0277	FAD linked oxidase domain protein
CS345_RS23520	COG1960	acyl-CoA dehydrogenase activity
CS345_RS23525	COG1960	acyl-CoA dehydrogenase activity
CS345_RS23550	COG2072	flavoprotein involved in K transport
CS345_RS23555	COG0604	alcohol dehydrogenase
CS345_RS23570	COG1024	Enoyl-CoA hydratase
CS345_RS23595	COG1522	sequence-specific DNA binding
CS345_RS23605	COG3708	Transcriptional regulator
CS345_RS23605	COG2207	Transcriptional regulator
CS345_RS23620	COG2814	Major facilitator Superfamily
CS345_RS23625	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CS345_RS23645	COG1999	signal sequence binding
CS345_RS23690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS345_RS23710	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS345_RS23715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS345_RS23725	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CS345_RS23730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CS345_RS23740	COG0069	glutamate synthase activity
CS345_RS23740	COG0070	glutamate synthase
CS345_RS23740	COG0067	glutamate synthase
CS345_RS23750	COG3047	cAMP biosynthetic process
CS345_RS23760	COG1127	ABC transporter
CS345_RS23765	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS345_RS23770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS345_RS23775	COG2853	Lipoprotein
CS345_RS23785	COG1131	(ABC) transporter
CS345_RS23790	COG0842	Transport permease protein
CS345_RS23800	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS345_RS23810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CS345_RS23815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS345_RS23820	COG0131	Imidazoleglycerol-phosphate dehydratase
CS345_RS23825	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CS345_RS23830	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CS345_RS23835	COG0107	imidazoleglycerol-phosphate synthase activity
CS345_RS23845	COG0140	phosphoribosyl-ATP diphosphatase activity
CS345_RS23850	COG0537	adenosine 5'-monophosphoramidase activity
CS345_RS23855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS345_RS23860	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS345_RS23880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CS345_RS23885	COG1970	mechanosensitive ion channel activity
CS345_RS23890	COG0723	plastoquinol--plastocyanin reductase activity
CS345_RS23895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CS345_RS23900	COG2857	Cytochrome c1
CS345_RS23905	COG0625	glutathione transferase activity
CS345_RS23910	COG2969	positive regulation of protein catabolic process
CS345_RS23945	COG1073	alpha beta
CS345_RS23955	COG0583	DNA-binding transcription factor activity
CS345_RS23960	COG0492	ferredoxin-NADP+ reductase activity
CS345_RS23980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS23990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS345_RS24005	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS24040	COG3702	type iv secretory pathway
CS345_RS24045	COG3451	type IV secretory pathway VirB4
CS345_RS24060	COG3736	Type IV secretory pathway, component VirB8
CS345_RS24070	COG2948	multi-organism process
CS345_RS24075	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CS345_RS24085	COG0697	spore germination
CS345_RS24105	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CS345_RS24110	COG0747	negative chemotaxis
CS345_RS24115	COG0601	transmembrane transport
CS345_RS24120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS345_RS24130	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CS345_RS24140	COG0513	Belongs to the DEAD box helicase family
CS345_RS24145	COG1280	lysine exporter protein (LysE YggA)
CS345_RS24150	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CS345_RS24170	COG0583	DNA-binding transcription factor activity
CS345_RS24180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS345_RS24190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS345_RS24195	COG0154	amidase activity
CS345_RS24200	COG1609	Transcriptional regulator
CS345_RS24220	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS345_RS24225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS345_RS24230	COG3842	ATPase activity
CS345_RS24235	COG1653	transport
CS345_RS24240	COG1175	transmembrane transport
CS345_RS24245	COG0395	ABC-type sugar transport system, permease component
CS345_RS24260	COG0018	arginyl-trna synthetase
CS345_RS24280	COG1280	lysine exporter protein (LysE YggA)
CS345_RS24295	COG1960	acyl-CoA dehydrogenase activity
CS345_RS24300	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CS345_RS24305	COG0183	Belongs to the thiolase family
CS345_RS24310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CS345_RS24325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS345_RS24330	COG3181	Tripartite tricarboxylate transporter family receptor
CS345_RS24340	COG2358	TRAP transporter, solute receptor (TAXI family
CS345_RS24350	COG1629	transport
CS345_RS24355	COG2922	Belongs to the Smg family
CS345_RS24360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS345_RS24380	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS345_RS24385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS24390	COG1028	Short-chain dehydrogenase reductase Sdr
CS345_RS24395	COG1012	belongs to the aldehyde dehydrogenase family
CS345_RS24405	COG0028	Belongs to the TPP enzyme family
CS345_RS24410	COG1522	sequence-specific DNA binding
CS345_RS24415	COG3781	membrane
CS345_RS24445	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS345_RS24470	COG1304	FMN binding
CS345_RS24485	COG0154	amidase activity
CS345_RS24490	COG1414	Transcriptional regulator
CS345_RS24515	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CS345_RS24520	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CS345_RS24525	COG0594	ribonuclease P activity
CS345_RS24530	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CS345_RS24535	COG0706	membrane insertase activity
CS345_RS24540	COG0753	catalase activity
CS345_RS24545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS345_RS24550	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CS345_RS24560	COG2175	clavaminate synthase activity
CS345_RS24565	COG1473	amidohydrolase
CS345_RS24570	COG4608	Belongs to the ABC transporter superfamily
CS345_RS24575	COG0444	Belongs to the ABC transporter superfamily
CS345_RS24585	COG0601	transmembrane transport
CS345_RS24590	COG0747	negative chemotaxis
CS345_RS24630	COG0436	Aminotransferase
CS345_RS24635	COG1278	Cold shock