locus-tag	class	description
CWR61_RS00005	COG0445	tRNA wobble uridine modification
CWR61_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
CWR61_RS00015	COG1192	Involved in chromosome partitioning
CWR61_RS00025	COG1475	DNA binding
CWR61_RS00030	COG0252	asparaginase activity
CWR61_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWR61_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWR61_RS00075	COG0081	regulation of translation
CWR61_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CWR61_RS00085	COG0222	ribosome binding
CWR61_RS00090	COG0085	RNA polymerase activity
CWR61_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CWR61_RS00130	COG1230	cation diffusion facilitator family transporter
CWR61_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CWR61_RS00145	COG0049	tRNA binding
CWR61_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWR61_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CWR61_RS00160	COG0051	transcription antitermination factor activity, RNA binding
CWR61_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CWR61_RS00175	COG0089	rRNA binding
CWR61_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CWR61_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CWR61_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CWR61_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CWR61_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
CWR61_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWR61_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CWR61_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CWR61_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CWR61_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CWR61_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CWR61_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CWR61_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWR61_RS00270	COG1841	ribosomal large subunit assembly
CWR61_RS00275	COG0200	Binds to the 23S rRNA
CWR61_RS00280	COG0201	protein transport
CWR61_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWR61_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWR61_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CWR61_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWR61_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CWR61_RS00310	COG0202	RNA polymerase activity
CWR61_RS00315	COG0203	ribosomal protein L17
CWR61_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
CWR61_RS00325	COG1324	tolerance protein
CWR61_RS00330	COG4232	protein-disulfide reductase activity
CWR61_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CWR61_RS00355	COG1333	cytochrome c biogenesis protein
CWR61_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWR61_RS00385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWR61_RS00390	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CWR61_RS00395	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CWR61_RS00410	COG2814	Major facilitator Superfamily
CWR61_RS00415	COG0629	single-stranded DNA binding
CWR61_RS00450	COG0402	S-adenosylhomocysteine deaminase activity
CWR61_RS00460	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS00480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS00510	COG2186	Transcriptional regulator
CWR61_RS00530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS00535	COG1956	GAF domain-containing protein
CWR61_RS00540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS00565	COG0531	amino acid
CWR61_RS00595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CWR61_RS00600	COG3568	Endonuclease Exonuclease Phosphatase
CWR61_RS00605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR61_RS00615	COG0477	Major facilitator Superfamily
CWR61_RS00640	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWR61_RS00660	COG0367	asparagine synthase
CWR61_RS00665	COG0463	Glycosyl transferase, family 2
CWR61_RS00720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWR61_RS00750	COG0859	PFAM glycosyl transferase family 9
CWR61_RS00765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CWR61_RS00775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWR61_RS00780	COG1127	ABC transporter
CWR61_RS00800	COG1686	Belongs to the peptidase S11 family
CWR61_RS00810	COG2921	Belongs to the UPF0250 family
CWR61_RS00815	COG0321	lipoyl(octanoyl) transferase activity
CWR61_RS00820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CWR61_RS00840	COG2096	Adenosyltransferase
CWR61_RS00855	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CWR61_RS00870	COG0523	cobalamin synthesis protein
CWR61_RS00875	COG0735	belongs to the Fur family
CWR61_RS00890	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWR61_RS00900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
CWR61_RS00910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CWR61_RS00920	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CWR61_RS00925	COG1560	Kdo2-lipid A biosynthetic process
CWR61_RS00935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CWR61_RS00955	COG1950	PFAM Membrane protein of
CWR61_RS00970	COG0583	DNA-binding transcription factor activity
CWR61_RS00985	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWR61_RS00995	COG0617	tRNA 3'-terminal CCA addition
CWR61_RS01005	COG0513	Belongs to the DEAD box helicase family
CWR61_RS01010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CWR61_RS01015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWR61_RS01025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWR61_RS01040	COG0735	belongs to the Fur family
CWR61_RS01060	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS01085	COG0640	Transcriptional regulator
CWR61_RS01145	COG0583	DNA-binding transcription factor activity
CWR61_RS01160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWR61_RS01165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS01170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS01185	COG0758	DNA mediated transformation
CWR61_RS01190	COG1522	sequence-specific DNA binding
CWR61_RS01200	COG0242	peptide deformylase activity
CWR61_RS01205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CWR61_RS01215	COG0546	phosphoglycolate phosphatase activity
CWR61_RS01235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWR61_RS01240	COG1942	4-Oxalocrotonate Tautomerase
CWR61_RS01245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS01275	COG0129	dihydroxy-acid dehydratase activity
CWR61_RS01280	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS01285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWR61_RS01295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWR61_RS01295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR61_RS01305	COG5000	phosphorelay sensor kinase activity
CWR61_RS01310	COG2204	response regulator
CWR61_RS01335	COG2068	MobA-Related Protein
CWR61_RS01345	COG3473	Maleate cis-trans isomerase
CWR61_RS01350	COG0596	Alpha beta hydrolase
CWR61_RS01355	COG2309	aminopeptidase activity
CWR61_RS01360	COG1335	isochorismatase
CWR61_RS01375	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR61_RS01385	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS01410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR61_RS01415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS01435	COG2226	methyltransferase
CWR61_RS01450	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS01455	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CWR61_RS01460	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CWR61_RS01465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWR61_RS01470	COG1054	Belongs to the UPF0176 family
CWR61_RS01475	COG0588	phosphoglycerate mutase activity
CWR61_RS01480	COG4942	peptidase
CWR61_RS01485	COG0793	Belongs to the peptidase S41A family
CWR61_RS01490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CWR61_RS01510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR61_RS01540	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CWR61_RS01545	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWR61_RS01550	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CWR61_RS01555	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CWR61_RS01565	COG0142	geranyltranstransferase activity
CWR61_RS01575	COG0583	DNA-binding transcription factor activity
CWR61_RS01585	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
CWR61_RS01590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS01615	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS01625	COG1802	Transcriptional regulator
CWR61_RS01650	COG1802	Transcriptional regulator
CWR61_RS01660	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS01670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS01690	COG0028	Belongs to the TPP enzyme family
CWR61_RS01700	COG0583	DNA-binding transcription factor activity
CWR61_RS01705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS01710	COG2301	Belongs to the HpcH HpaI aldolase family
CWR61_RS01715	COG2188	Transcriptional regulator
CWR61_RS01760	COG0583	DNA-binding transcription factor activity
CWR61_RS01765	COG1024	Enoyl-CoA hydratase
CWR61_RS01800	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS01815	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS01840	COG0745	RESPONSE REGULATOR receiver
CWR61_RS01870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CWR61_RS01875	COG2890	protein-(glutamine-N5) methyltransferase activity
CWR61_RS01880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CWR61_RS01890	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS01925	COG1464	Belongs to the NlpA lipoprotein family
CWR61_RS01955	COG4211	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS01960	COG0583	DNA-binding transcription factor activity
CWR61_RS01965	COG0683	leucine binding
CWR61_RS01970	COG0154	amidase activity
CWR61_RS01975	COG0288	reversible hydration of carbon dioxide
CWR61_RS01995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR61_RS02010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWR61_RS02020	COG1414	Transcriptional regulator
CWR61_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS02030	COG2031	fatty acid transporter
CWR61_RS02035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS02050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CWR61_RS02055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CWR61_RS02075	COG2808	Putative FMN-binding domain
CWR61_RS02080	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR61_RS02085	COG0747	negative chemotaxis
CWR61_RS02090	COG0657	acetylesterase activity
CWR61_RS02105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR61_RS02110	COG2207	Transcriptional regulator
CWR61_RS02120	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CWR61_RS02125	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CWR61_RS02135	COG1538	Outer membrane efflux protein
CWR61_RS02150	COG0583	DNA-binding transcription factor activity
CWR61_RS02155	COG0628	permease
CWR61_RS02165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CWR61_RS02170	COG0251	oxidation-reduction process
CWR61_RS02180	COG0330	HflC and HflK could
CWR61_RS02185	COG3422	double-strand break repair
CWR61_RS02200	COG0583	DNA-binding transcription factor activity
CWR61_RS02235	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS02240	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS02245	COG1414	Transcriptional regulator
CWR61_RS02250	COG1024	Enoyl-CoA hydratase
CWR61_RS02255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS02265	COG0604	alcohol dehydrogenase
CWR61_RS02270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02275	COG0583	DNA-binding transcription factor activity
CWR61_RS02285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02300	COG0251	oxidation-reduction process
CWR61_RS02305	COG1017	nitric oxide dioxygenase activity
CWR61_RS02305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWR61_RS02310	COG2031	fatty acid transporter
CWR61_RS02315	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS02340	COG1278	Cold shock
CWR61_RS02345	COG0583	DNA-binding transcription factor activity
CWR61_RS02355	COG3119	arylsulfatase activity
CWR61_RS02365	COG1819	glycosyl
CWR61_RS02375	COG1204	response to ionizing radiation
CWR61_RS02395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWR61_RS02400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS02405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS02425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CWR61_RS02440	COG0326	Molecular chaperone. Has ATPase activity
CWR61_RS02445	COG0625	glutathione transferase activity
CWR61_RS02460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CWR61_RS02465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWR61_RS02475	COG1652	LysM domain
CWR61_RS02500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR61_RS02540	COG0583	DNA-binding transcription factor activity
CWR61_RS02555	COG1024	Enoyl-CoA hydratase
CWR61_RS02560	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS02585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02590	COG1024	Enoyl-CoA hydratase
CWR61_RS02590	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS02595	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS02600	COG1414	Transcriptional regulator
CWR61_RS02620	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS02625	COG1609	Transcriptional regulator
CWR61_RS02635	COG1053	succinate dehydrogenase
CWR61_RS02635	COG3976	FMN-binding domain protein
CWR61_RS02670	COG0683	leucine binding
CWR61_RS02675	COG1309	transcriptional regulator
CWR61_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS02700	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS02710	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS02720	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CWR61_RS02730	COG2030	dehydratase
CWR61_RS02740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02765	COG1024	Enoyl-CoA hydratase
CWR61_RS02775	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS02795	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR61_RS02795	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS02810	COG0427	acetyl-CoA hydrolase
CWR61_RS02815	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS02835	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS02850	COG0183	Belongs to the thiolase family
CWR61_RS02855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR61_RS02865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS02870	COG0583	DNA-binding transcription factor activity
CWR61_RS02875	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS02890	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CWR61_RS02915	COG1309	transcriptional regulator
CWR61_RS02925	COG1024	Enoyl-CoA hydratase
CWR61_RS02950	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS02955	COG0431	NADPH-dependent FMN reductase
CWR61_RS02960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS02965	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR61_RS02980	COG1414	Transcriptional regulator
CWR61_RS02985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWR61_RS02990	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS02995	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS03025	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS03050	COG1024	Enoyl-CoA hydratase
CWR61_RS03060	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS03065	COG1024	Enoyl-CoA hydratase
CWR61_RS03070	COG0183	Belongs to the thiolase family
CWR61_RS03075	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS03090	COG0583	DNA-binding transcription factor activity
CWR61_RS03095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR61_RS03110	COG0625	glutathione transferase activity
CWR61_RS03115	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS03125	COG2186	Transcriptional regulator
CWR61_RS03130	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS03135	COG0626	cystathionine gamma-synthase activity
CWR61_RS03175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS03180	COG0436	Aminotransferase
CWR61_RS03185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS03190	COG0765	amino acid transport
CWR61_RS03195	COG1126	abc transporter atp-binding protein
CWR61_RS03200	COG1473	amidohydrolase
CWR61_RS03205	COG1414	Transcriptional regulator
CWR61_RS03215	COG0154	amidase activity
CWR61_RS03275	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS03290	COG3135	benzoate transporter
CWR61_RS03315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR61_RS03320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS03325	COG1335	isochorismatase
CWR61_RS03375	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS03380	COG0633	Ferredoxin
CWR61_RS03380	COG0543	2 iron, 2 sulfur cluster binding
CWR61_RS03385	COG4638	Rieske (2fe-2S)
CWR61_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS03405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR61_RS03425	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS03430	COG3384	dioxygenase
CWR61_RS03440	COG3971	2-oxopent-4-enoate hydratase activity
CWR61_RS03460	COG0028	Belongs to the TPP enzyme family
CWR61_RS03495	COG1024	Enoyl-CoA hydratase
CWR61_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS03505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS03520	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS03565	COG0183	Belongs to the thiolase family
CWR61_RS03570	COG2030	dehydratase
CWR61_RS03580	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS03595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS03645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWR61_RS03650	COG3409	Peptidoglycan-binding domain 1 protein
CWR61_RS03650	COG3267	Type II secretory pathway component ExeA
CWR61_RS03660	COG1450	Type ii and iii secretion system protein
CWR61_RS03705	COG0387	Pfam Sodium calcium exchanger
CWR61_RS03715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR61_RS03765	COG4772	TonB-dependent receptor
CWR61_RS03775	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWR61_RS03800	COG1054	Belongs to the UPF0176 family
CWR61_RS03815	COG0489	protein tyrosine kinase activity
CWR61_RS03860	COG2081	HI0933 family
CWR61_RS03865	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWR61_RS03875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWR61_RS03880	COG0509	glycine decarboxylation via glycine cleavage system
CWR61_RS03885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CWR61_RS03885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CWR61_RS03905	COG1024	Enoyl-CoA hydratase
CWR61_RS03925	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS03935	COG0601	transmembrane transport
CWR61_RS03940	COG0747	negative chemotaxis
CWR61_RS03950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR61_RS03955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS03975	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CWR61_RS03980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWR61_RS03985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWR61_RS04000	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS04015	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS04020	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS04025	COG0166	Belongs to the GPI family
CWR61_RS04040	COG0277	FAD linked oxidase domain protein
CWR61_RS04045	COG0745	RESPONSE REGULATOR receiver
CWR61_RS04050	COG2205	protein histidine kinase activity
CWR61_RS04055	COG1368	sulfuric ester hydrolase activity
CWR61_RS04065	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CWR61_RS04090	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWR61_RS04100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CWR61_RS04105	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CWR61_RS04135	COG0012	GTP binding
CWR61_RS04150	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CWR61_RS04155	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CWR61_RS04190	COG1309	transcriptional regulator
CWR61_RS04200	COG2814	Major facilitator Superfamily
CWR61_RS04225	COG0281	malic enzyme
CWR61_RS04225	COG0280	phosphate acetyltransferase
CWR61_RS04235	COG0601	transmembrane transport
CWR61_RS04240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS04245	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS04250	COG0747	negative chemotaxis
CWR61_RS04260	COG0583	DNA-binding transcription factor activity
CWR61_RS04275	COG0640	Transcriptional regulator
CWR61_RS04290	COG3135	benzoate transporter
CWR61_RS04295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWR61_RS04300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CWR61_RS04305	COG0742	ribosomal rna small subunit methyltransferase
CWR61_RS04320	COG3639	organic phosphonate transmembrane transporter activity
CWR61_RS04325	COG3639	organic phosphonate transmembrane transporter activity
CWR61_RS04330	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CWR61_RS04355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CWR61_RS04360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR61_RS04370	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CWR61_RS04375	COG1058	Belongs to the CinA family
CWR61_RS04375	COG1546	Belongs to the CinA family
CWR61_RS04380	COG0284	orotidine-5'-phosphate decarboxylase activity
CWR61_RS04385	COG1252	NADH dehydrogenase
CWR61_RS04400	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS04410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWR61_RS04435	COG0431	NADPH-dependent FMN reductase
CWR61_RS04455	COG1053	succinate dehydrogenase
CWR61_RS04465	COG0583	DNA-binding transcription factor activity
CWR61_RS04470	COG1053	succinate dehydrogenase
CWR61_RS04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS04490	COG0789	Transcriptional regulator
CWR61_RS04495	COG0633	Ferredoxin
CWR61_RS04505	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS04525	COG1335	isochorismatase
CWR61_RS04540	COG0405	Gamma-glutamyltransferase
CWR61_RS04555	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS04560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS04565	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS04570	COG0583	DNA-binding transcription factor activity
CWR61_RS04595	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS04600	COG0583	DNA-binding transcription factor activity
CWR61_RS04605	COG2199	diguanylate cyclase activity
CWR61_RS04630	COG3842	ATPase activity
CWR61_RS04655	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS04655	COG1024	Enoyl-CoA hydratase
CWR61_RS04660	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS04675	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS04685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS04690	COG0747	negative chemotaxis
CWR61_RS04710	COG2423	ornithine cyclodeaminase activity
CWR61_RS04720	COG0473	3-isopropylmalate dehydrogenase activity
CWR61_RS04725	COG0066	3-isopropylmalate dehydratase activity
CWR61_RS04730	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWR61_RS04740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS04750	COG0583	DNA-binding transcription factor activity
CWR61_RS04770	COG0583	DNA-binding transcription factor activity
CWR61_RS04775	COG3119	arylsulfatase activity
CWR61_RS04785	COG0583	DNA-binding transcription factor activity
CWR61_RS04795	COG1024	Enoyl-CoA hydratase
CWR61_RS04805	COG2084	Dehydrogenase
CWR61_RS04825	COG1850	ribulose-bisphosphate carboxylase activity
CWR61_RS04845	COG0583	DNA-binding transcription factor activity
CWR61_RS04850	COG1024	Enoyl-CoA hydratase
CWR61_RS04875	COG3842	ATPase activity
CWR61_RS04880	COG1177	transmembrane transport
CWR61_RS04895	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS04900	COG3386	PFAM SMP-30 Gluconolaconase
CWR61_RS04910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR61_RS04930	COG0583	DNA-binding transcription factor activity
CWR61_RS04940	COG0583	DNA-binding transcription factor activity
CWR61_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS04960	COG3246	L-lysine catabolic process to acetate
CWR61_RS04965	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS04980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS04985	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS05005	COG0596	Alpha beta hydrolase
CWR61_RS05020	COG1335	isochorismatase
CWR61_RS05025	COG0583	DNA-binding transcription factor activity
CWR61_RS05040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS05055	COG0183	Belongs to the thiolase family
CWR61_RS05060	COG1024	Enoyl-CoA hydratase
CWR61_RS05070	COG1024	Enoyl-CoA hydratase
CWR61_RS05075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS05080	COG0583	DNA-binding transcription factor activity
CWR61_RS05085	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS05110	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS05120	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWR61_RS05125	COG4191	Histidine kinase
CWR61_RS05130	COG4566	intracellular signal transduction
CWR61_RS05160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS05170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWR61_RS05215	COG0583	DNA-binding transcription factor activity
CWR61_RS05235	COG1024	Enoyl-CoA hydratase
CWR61_RS05240	COG1024	Enoyl-CoA hydratase
CWR61_RS05245	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS05250	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS05290	COG3685	Protein conserved in bacteria
CWR61_RS05300	COG0387	Pfam Sodium calcium exchanger
CWR61_RS05305	COG3795	YCII-related domain
CWR61_RS05310	COG2188	Transcriptional regulator
CWR61_RS05330	COG0154	amidase activity
CWR61_RS05335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS05340	COG1024	Enoyl-CoA hydratase
CWR61_RS05350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS05370	COG1414	Transcriptional regulator
CWR61_RS05385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR61_RS05390	COG0251	oxidation-reduction process
CWR61_RS05395	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS05415	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS05420	COG1414	Transcriptional regulator
CWR61_RS05440	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS05450	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS05460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWR61_RS05465	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS05470	COG0583	DNA-binding transcription factor activity
CWR61_RS05480	COG0590	tRNA wobble adenosine to inosine editing
CWR61_RS05485	COG2807	transmembrane transport
CWR61_RS05495	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS05500	COG0154	amidase activity
CWR61_RS05505	COG0307	riboflavin synthase, alpha
CWR61_RS05515	COG1522	sequence-specific DNA binding
CWR61_RS05525	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS05535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS05545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWR61_RS05555	COG1063	alcohol dehydrogenase
CWR61_RS05575	COG1418	mRNA catabolic process
CWR61_RS05580	COG1448	Aminotransferase
CWR61_RS05585	COG0583	DNA-binding transcription factor activity
CWR61_RS05595	COG0477	Major facilitator Superfamily
CWR61_RS05600	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS05610	COG1335	isochorismatase
CWR61_RS05635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS05640	COG2274	protein secretion by the type I secretion system
CWR61_RS05650	COG1538	Outer membrane efflux protein
CWR61_RS05655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CWR61_RS05655	COG0493	'glutamate synthase
CWR61_RS05665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CWR61_RS05675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS05685	COG1309	transcriptional regulator
CWR61_RS05690	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS05700	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS05710	COG1309	transcriptional regulator
CWR61_RS05720	COG0583	DNA-binding transcription factor activity
CWR61_RS05765	COG0840	transmembrane signaling receptor activity
CWR61_RS05770	COG0653	protein targeting
CWR61_RS05785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS05800	COG2203	Gaf domain
CWR61_RS05800	COG2199	diguanylate cyclase activity
CWR61_RS05825	COG0154	amidase activity
CWR61_RS05830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS05830	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS05840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS05855	COG3945	hemerythrin HHE cation binding domain
CWR61_RS05870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWR61_RS05870	COG2169	Transcriptional regulator
CWR61_RS05890	COG1271	oxidase subunit
CWR61_RS05895	COG1294	oxidase, subunit
CWR61_RS05905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS05935	COG0596	Alpha beta hydrolase
CWR61_RS05940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWR61_RS05960	COG0583	DNA-binding transcription factor activity
CWR61_RS05980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CWR61_RS05985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CWR61_RS05995	COG2070	2-Nitropropane dioxygenase
CWR61_RS06015	COG1917	Cupin 2, conserved barrel domain protein
CWR61_RS06015	COG2207	Transcriptional regulator
CWR61_RS06035	COG2900	Belongs to the SlyX family
CWR61_RS06045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR61_RS06070	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS06075	COG0583	DNA-binding transcription factor activity
CWR61_RS06080	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS06090	COG0583	DNA-binding transcription factor activity
CWR61_RS06115	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CWR61_RS06125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR61_RS06130	COG1845	cytochrome c oxidase, subunit III
CWR61_RS06135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CWR61_RS06140	COG0640	Transcriptional regulator
CWR61_RS06160	COG3220	belongs to the UPF0276 family
CWR61_RS06215	COG1666	GTP binding
CWR61_RS06245	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS06255	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CWR61_RS06260	COG1845	cytochrome c oxidase, subunit III
CWR61_RS06265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR61_RS06270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CWR61_RS06275	COG0477	Major facilitator Superfamily
CWR61_RS06290	COG5006	permease, DMT superfamily
CWR61_RS06310	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWR61_RS06320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CWR61_RS06325	COG3383	formate dehydrogenase (NAD+) activity
CWR61_RS06345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CWR61_RS06350	COG0303	'Molybdopterin
CWR61_RS06355	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWR61_RS06365	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CWR61_RS06370	COG0315	cyclic pyranopterin monophosphate synthase activity
CWR61_RS06380	COG0412	Dienelactone hydrolase
CWR61_RS06390	COG0678	peroxiredoxin activity
CWR61_RS06400	COG0697	spore germination
CWR61_RS06445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWR61_RS06455	COG1335	isochorismatase
CWR61_RS06460	COG0523	cobalamin synthesis protein
CWR61_RS06490	COG1802	Transcriptional regulator
CWR61_RS06510	COG0667	Aldo Keto reductase
CWR61_RS06515	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CWR61_RS06520	COG4535	Mg2 and Co2 transporter CorC
CWR61_RS06525	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CWR61_RS06530	COG1702	phosphate starvation-inducible protein PhoH
CWR61_RS06535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CWR61_RS06545	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR61_RS06550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CWR61_RS06555	COG1862	Preprotein translocase
CWR61_RS06560	COG0343	queuine tRNA-ribosyltransferase activity
CWR61_RS06565	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CWR61_RS06570	COG2027	D-alanyl-D-alanine carboxypeptidase
CWR61_RS06580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CWR61_RS06580	COG1648	precorrin-2 dehydrogenase activity
CWR61_RS06605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CWR61_RS06610	COG0741	lytic transglycosylase activity
CWR61_RS06615	COG0436	Aminotransferase
CWR61_RS06625	COG0281	malic enzyme
CWR61_RS06625	COG0280	phosphate acetyltransferase
CWR61_RS06635	COG2732	(Barnase) inhibitor
CWR61_RS06640	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWR61_RS06645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWR61_RS06650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CWR61_RS06655	COG0126	phosphoglycerate kinase activity
CWR61_RS06660	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CWR61_RS06665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CWR61_RS06680	COG0625	glutathione transferase activity
CWR61_RS06710	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CWR61_RS06720	COG0306	phosphate transporter
CWR61_RS06725	COG0521	Mo-molybdopterin cofactor biosynthetic process
CWR61_RS06735	COG0739	heme binding
CWR61_RS06745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWR61_RS06795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CWR61_RS06805	COG2944	sequence-specific DNA binding
CWR61_RS06815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CWR61_RS06820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWR61_RS06825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CWR61_RS06830	COG0009	L-threonylcarbamoyladenylate synthase
CWR61_RS06835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS06840	COG1414	Transcriptional regulator
CWR61_RS06855	COG0765	amino acid transport
CWR61_RS06860	COG1126	abc transporter atp-binding protein
CWR61_RS06865	COG0028	Belongs to the TPP enzyme family
CWR61_RS06880	COG0028	Belongs to the TPP enzyme family
CWR61_RS06885	COG0583	DNA-binding transcription factor activity
CWR61_RS06890	COG4974	Belongs to the 'phage' integrase family
CWR61_RS06895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWR61_RS06900	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CWR61_RS06910	COG1686	Belongs to the peptidase S11 family
CWR61_RS06920	COG2814	Major facilitator Superfamily
CWR61_RS06930	COG1074	ATP-dependent DNA helicase activity
CWR61_RS06940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWR61_RS06955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS06960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWR61_RS06970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS06980	COG0505	Belongs to the CarA family
CWR61_RS06985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CWR61_RS06990	COG4221	oxidoreductase activity
CWR61_RS06995	COG0406	alpha-ribazole phosphatase activity
CWR61_RS07005	COG3842	ATPase activity
CWR61_RS07025	COG2233	PERMEase
CWR61_RS07030	COG0840	transmembrane signaling receptor activity
CWR61_RS07035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWR61_RS07040	COG1534	Rna-binding protein
CWR61_RS07045	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CWR61_RS07050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWR61_RS07135	COG2010	Cytochrome c
CWR61_RS07180	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS07205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS07250	COG1137	ATPase activity
CWR61_RS07260	COG0154	amidase activity
CWR61_RS07265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS07290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS07295	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS07300	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS07310	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR61_RS07320	COG1522	sequence-specific DNA binding
CWR61_RS07325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR61_RS07330	COG1473	amidohydrolase
CWR61_RS07335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS07340	COG4597	amino acid ABC transporter
CWR61_RS07345	COG0765	amino acid transport
CWR61_RS07350	COG1126	abc transporter atp-binding protein
CWR61_RS07360	COG0436	Aminotransferase
CWR61_RS07365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR61_RS07405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CWR61_RS07410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWR61_RS07430	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS07435	COG3546	catalase activity
CWR61_RS07440	COG2985	domain, Protein
CWR61_RS07445	COG0583	DNA-binding transcription factor activity
CWR61_RS07480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWR61_RS07500	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS07520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWR61_RS07530	COG1132	(ABC) transporter
CWR61_RS07555	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CWR61_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS07575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CWR61_RS07585	COG0511	ligase activity, forming carbon-carbon bonds
CWR61_RS07610	COG2188	Transcriptional regulator
CWR61_RS07615	COG0439	Biotin carboxylase
CWR61_RS07625	COG0511	ligase activity, forming carbon-carbon bonds
CWR61_RS07640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS07670	COG3971	2-oxopent-4-enoate hydratase activity
CWR61_RS07675	COG0583	DNA-binding transcription factor activity
CWR61_RS07690	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR61_RS07730	COG1129	ABC transporter
CWR61_RS07740	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS07780	COG0251	oxidation-reduction process
CWR61_RS07790	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS07820	COG4789	Type iii secretion
CWR61_RS07920	COG4790	Type iii secretion
CWR61_RS07925	COG4794	Type iii secretion
CWR61_RS07930	COG4791	protein targeting
CWR61_RS07935	COG4792	protein secretion
CWR61_RS07950	COG1595	DNA-templated transcription, initiation
CWR61_RS07970	COG2208	phosphoserine phosphatase activity
CWR61_RS07970	COG2770	Histidine kinase
CWR61_RS07980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWR61_RS07985	COG2172	sigma factor antagonist activity
CWR61_RS07990	COG1366	Belongs to the anti-sigma-factor antagonist family
CWR61_RS07995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR61_RS08045	COG2321	neutral zinc metallopeptidase
CWR61_RS08050	COG0009	L-threonylcarbamoyladenylate synthase
CWR61_RS08055	COG1994	Peptidase M50
CWR61_RS08060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS08065	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CWR61_RS08070	COG3539	Fimbrial protein
CWR61_RS08080	COG2850	peptidyl-arginine hydroxylation
CWR61_RS08090	COG3360	Dodecin
CWR61_RS08125	COG0668	transmembrane transport
CWR61_RS08145	COG0483	inositol monophosphate 1-phosphatase activity
CWR61_RS08150	COG1253	flavin adenine dinucleotide binding
CWR61_RS08160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWR61_RS08185	COG0825	malonyl-CoA metabolic process
CWR61_RS08190	COG0037	tRNA processing
CWR61_RS08195	COG0527	aspartate kinase activity
CWR61_RS08205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWR61_RS08210	COG4948	Mandelate Racemase Muconate Lactonizing
CWR61_RS08220	COG2186	Transcriptional regulator
CWR61_RS08240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS08240	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS08255	COG2267	carboxylic ester hydrolase activity
CWR61_RS08265	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS08275	COG0583	DNA-binding transcription factor activity
CWR61_RS08300	COG3842	ATPase activity
CWR61_RS08310	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR61_RS08310	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS08315	COG1414	Transcriptional regulator
CWR61_RS08320	COG1832	CoA-binding protein
CWR61_RS08330	COG0251	oxidation-reduction process
CWR61_RS08355	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS08365	COG1215	transferase activity, transferring glycosyl groups
CWR61_RS08370	COG0726	polysaccharide deacetylase
CWR61_RS08370	COG1649	PFAM Uncharacterised BCR, COG1649
CWR61_RS08390	COG1846	Transcriptional regulator
CWR61_RS08410	COG0410	ABC transporter
CWR61_RS08415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWR61_RS08415	COG2010	Cytochrome c
CWR61_RS08420	COG2080	2 iron, 2 sulfur cluster binding
CWR61_RS08425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR61_RS08430	COG3473	Maleate cis-trans isomerase
CWR61_RS08435	COG0596	Alpha beta hydrolase
CWR61_RS08440	COG2309	aminopeptidase activity
CWR61_RS08445	COG1335	isochorismatase
CWR61_RS08455	COG1017	nitric oxide dioxygenase activity
CWR61_RS08455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWR61_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS08475	COG0183	Belongs to the thiolase family
CWR61_RS08480	COG1024	Enoyl-CoA hydratase
CWR61_RS08480	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS08490	COG1024	Enoyl-CoA hydratase
CWR61_RS08490	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS08495	COG0183	Belongs to the thiolase family
CWR61_RS08515	COG2197	response regulator
CWR61_RS08530	COG0166	Belongs to the GPI family
CWR61_RS08535	COG1045	serine acetyltransferase
CWR61_RS08545	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CWR61_RS08555	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS08560	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWR61_RS08575	COG0210	DNA helicase
CWR61_RS08580	COG0598	Magnesium transport protein CorA
CWR61_RS08590	COG0747	negative chemotaxis
CWR61_RS08595	COG0601	transmembrane transport
CWR61_RS08600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS08605	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS08610	COG1846	Transcriptional regulator
CWR61_RS08655	COG4964	Belongs to the GSP D family
CWR61_RS08720	COG3474	cytochrome
CWR61_RS08725	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CWR61_RS08740	COG3384	dioxygenase
CWR61_RS08745	COG0583	DNA-binding transcription factor activity
CWR61_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS08755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CWR61_RS08810	COG0697	spore germination
CWR61_RS08815	COG0730	response to heat
CWR61_RS08830	COG1511	domain protein
CWR61_RS08830	COG3264	Mechanosensitive ion channel
CWR61_RS08835	COG0583	DNA-binding transcription factor activity
CWR61_RS08840	COG0427	acetyl-CoA hydrolase
CWR61_RS08845	COG0385	Bile acid
CWR61_RS08895	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS08900	COG0154	amidase activity
CWR61_RS08910	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CWR61_RS08925	COG0495	leucyl-tRNA aminoacylation
CWR61_RS08930	COG2814	Major facilitator Superfamily
CWR61_RS08955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWR61_RS08960	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWR61_RS08965	COG2814	Major facilitator Superfamily
CWR61_RS08970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CWR61_RS08980	COG4176	ABC-type proline glycine betaine transport system permease component
CWR61_RS08985	COG0517	IMP dehydrogenase activity
CWR61_RS08985	COG4175	Glycine betaine
CWR61_RS08990	COG1942	4-Oxalocrotonate Tautomerase
CWR61_RS08995	COG0183	Belongs to the thiolase family
CWR61_RS09005	COG1802	Transcriptional regulator
CWR61_RS09015	COG1024	Enoyl-CoA hydratase
CWR61_RS09020	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS09045	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CWR61_RS09065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS09070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWR61_RS09080	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CWR61_RS09085	COG0736	holo-[acyl-carrier-protein] synthase activity
CWR61_RS09100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWR61_RS09110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CWR61_RS09110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CWR61_RS09115	COG2224	Isocitrate lyase
CWR61_RS09125	COG1346	cytolysis
CWR61_RS09130	COG1380	Effector of murein hydrolase LrgA
CWR61_RS09135	COG4106	trans-aconitate 2-methyltransferase activity
CWR61_RS09135	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CWR61_RS09145	COG0156	8-amino-7-oxononanoate synthase activity
CWR61_RS09155	COG2217	Heavy metal translocating P-type atpase
CWR61_RS09165	COG3278	Belongs to the heme-copper respiratory oxidase family
CWR61_RS09185	COG0348	domain, Protein
CWR61_RS09210	COG1131	(ABC) transporter
CWR61_RS09215	COG0842	Transport permease protein
CWR61_RS09220	COG0628	permease
CWR61_RS09235	COG2814	Major facilitator Superfamily
CWR61_RS09240	COG2841	Protein conserved in bacteria
CWR61_RS09265	COG0765	amino acid transport
CWR61_RS09270	COG0765	amino acid transport
CWR61_RS09275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS09310	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS09325	COG3530	Putative quorum-sensing-regulated virulence factor
CWR61_RS09330	COG0494	nUDIX hydrolase
CWR61_RS09345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CWR61_RS09350	COG0542	response to heat
CWR61_RS09355	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS09365	COG5441	Belongs to the UPF0261 family
CWR61_RS09370	COG5564	TIM-barrel signal transduction protein
CWR61_RS09385	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWR61_RS09400	COG1477	protein flavinylation
CWR61_RS09420	COG1131	(ABC) transporter
CWR61_RS09425	COG0842	Transport permease protein
CWR61_RS09435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWR61_RS09440	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CWR61_RS09440	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CWR61_RS09445	COG1562	ergosterol biosynthetic process
CWR61_RS09450	COG1562	ergosterol biosynthetic process
CWR61_RS09455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CWR61_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS09475	COG2304	oxidoreductase activity
CWR61_RS09495	COG0534	Mate efflux family protein
CWR61_RS09510	COG3483	tryptophan 2,3-dioxygenase activity
CWR61_RS09515	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CWR61_RS09520	COG2003	Belongs to the UPF0758 family
CWR61_RS09525	COG1047	Peptidyl-prolyl cis-trans
CWR61_RS09530	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CWR61_RS09555	COG0523	cobalamin synthesis protein
CWR61_RS09565	COG0583	DNA-binding transcription factor activity
CWR61_RS09575	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CWR61_RS09580	COG1187	pseudouridine synthase activity
CWR61_RS09585	COG0779	Required for maturation of 30S ribosomal subunits
CWR61_RS09590	COG2251	uridine kinase activity
CWR61_RS09590	COG0195	Participates in both transcription termination and antitermination
CWR61_RS09595	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWR61_RS09600	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CWR61_RS09605	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWR61_RS09610	COG1217	gtp-binding protein TYPA
CWR61_RS09625	COG1611	Belongs to the LOG family
CWR61_RS09640	COG0412	Dienelactone hydrolase
CWR61_RS09645	COG1283	sodium-dependent phosphate transmembrane transporter activity
CWR61_RS09650	COG1760	l-serine dehydratase
CWR61_RS09655	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CWR61_RS09660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CWR61_RS09670	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CWR61_RS09695	COG2311	Membrane
CWR61_RS09705	COG2358	TRAP transporter, solute receptor (TAXI family
CWR61_RS09710	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR61_RS09725	COG0456	acetyltransferase
CWR61_RS09740	COG5285	phytanoyl-CoA dioxygenase
CWR61_RS09750	COG3395	kinase activity
CWR61_RS09755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CWR61_RS09770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CWR61_RS09780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS09805	COG0747	negative chemotaxis
CWR61_RS09810	COG0601	transmembrane transport
CWR61_RS09815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS09825	COG0154	amidase activity
CWR61_RS09870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CWR61_RS09875	COG0425	Belongs to the sulfur carrier protein TusA family
CWR61_RS09885	COG0228	four-way junction DNA binding
CWR61_RS09895	COG0336	Belongs to the RNA methyltransferase TrmD family
CWR61_RS09900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWR61_RS09910	COG0642	Histidine kinase
CWR61_RS09925	COG0525	valine-tRNA ligase activity
CWR61_RS09930	COG0105	UTP biosynthetic process
CWR61_RS09935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CWR61_RS09955	COG2976	Protein conserved in bacteria
CWR61_RS09960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR61_RS09965	COG1160	GTP binding
CWR61_RS09975	COG1923	regulation of RNA biosynthetic process
CWR61_RS09980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWR61_RS09985	COG0330	HflC and HflK could
CWR61_RS09990	COG0330	HflC and HflK could
CWR61_RS10000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CWR61_RS10005	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CWR61_RS10010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CWR61_RS10020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWR61_RS10030	COG4680	protein conserved in bacteria
CWR61_RS10075	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS10085	COG4638	Rieske (2fe-2S)
CWR61_RS10105	COG0633	Ferredoxin
CWR61_RS10110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS10140	COG0583	DNA-binding transcription factor activity
CWR61_RS10155	COG0028	Belongs to the TPP enzyme family
CWR61_RS10160	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS10165	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS10185	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CWR61_RS10195	COG3829	transcription factor binding
CWR61_RS10225	COG0833	amino acid
CWR61_RS10240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWR61_RS10245	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CWR61_RS10250	COG0840	transmembrane signaling receptor activity
CWR61_RS10275	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS10280	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS10305	COG0583	DNA-binding transcription factor activity
CWR61_RS10310	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS10330	COG5265	(ABC) transporter
CWR61_RS10340	COG0667	Aldo Keto reductase
CWR61_RS10355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWR61_RS10395	COG1959	2 iron, 2 sulfur cluster binding
CWR61_RS10400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS10405	COG0587	DNA-directed DNA polymerase activity
CWR61_RS10420	COG0400	carboxylic ester hydrolase activity
CWR61_RS10430	COG1566	PFAM secretion protein HlyD family protein
CWR61_RS10440	COG1289	transmembrane transporter activity
CWR61_RS10455	COG0235	Class ii aldolase
CWR61_RS10460	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS10465	COG0720	synthase
CWR61_RS10470	COG0602	queuosine metabolic process
CWR61_RS10495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS10535	COG3842	ATPase activity
CWR61_RS10545	COG0395	ABC-type sugar transport system, permease component
CWR61_RS10575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS10580	COG0420	3'-5' exonuclease activity
CWR61_RS10590	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS10595	COG2111	Na H antiporter
CWR61_RS10595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CWR61_RS10600	COG1006	Multisubunit Na H antiporter MnhC subunit
CWR61_RS10605	COG0651	ATP synthesis coupled electron transport
CWR61_RS10610	COG1863	multisubunit Na H antiporter MnhE subunit
CWR61_RS10615	COG2212	antiporter activity
CWR61_RS10635	COG0590	tRNA wobble adenosine to inosine editing
CWR61_RS10640	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWR61_RS10645	COG1024	Enoyl-CoA hydratase
CWR61_RS10660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS10665	COG0488	(ABC) transporter
CWR61_RS10695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR61_RS10700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CWR61_RS10705	COG2252	PERMEase
CWR61_RS10710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWR61_RS10715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CWR61_RS10720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CWR61_RS10750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWR61_RS10755	COG0789	Transcriptional regulator
CWR61_RS10765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWR61_RS10765	COG0678	peroxiredoxin activity
CWR61_RS10775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CWR61_RS10780	COG0584	glycerophosphoryl diester phosphodiesterase
CWR61_RS10785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWR61_RS10795	COG4181	ATPase activity
CWR61_RS10820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS10835	COG4336	lyase activity
CWR61_RS10850	COG2197	response regulator
CWR61_RS10855	COG3064	Membrane
CWR61_RS10855	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR61_RS10855	COG3210	domain, Protein
CWR61_RS10865	COG3121	Chaperone
CWR61_RS10875	COG3539	Fimbrial protein
CWR61_RS10880	COG2831	hemolysin activation secretion protein
CWR61_RS10895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS10920	COG0583	DNA-binding transcription factor activity
CWR61_RS10940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS10945	COG0765	amino acid transport
CWR61_RS10950	COG1126	abc transporter atp-binding protein
CWR61_RS10955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWR61_RS10960	COG1758	RNA polymerase activity
CWR61_RS10965	COG0194	GDP metabolic process
CWR61_RS10970	COG3258	Cytochrome c
CWR61_RS10975	COG2863	cytochrome
CWR61_RS10980	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS10985	COG0791	NLP P60 protein
CWR61_RS10990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWR61_RS11000	COG1561	YicC-like family, N-terminal region
CWR61_RS11005	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CWR61_RS11030	COG5002	protein histidine kinase activity
CWR61_RS11030	COG5001	Diguanylate cyclase
CWR61_RS11035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CWR61_RS11040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWR61_RS11045	COG0174	glutamine synthetase
CWR61_RS11055	COG2204	response regulator
CWR61_RS11060	COG0583	DNA-binding transcription factor activity
CWR61_RS11065	COG1741	Belongs to the pirin family
CWR61_RS11070	COG1741	Belongs to the pirin family
CWR61_RS11075	COG3842	ATPase activity
CWR61_RS11080	COG1178	ABC-type Fe3 transport system permease component
CWR61_RS11085	COG1840	ABC-type Fe3 transport system, periplasmic component
CWR61_RS11095	COG0583	DNA-binding transcription factor activity
CWR61_RS11100	COG2814	Major facilitator Superfamily
CWR61_RS11105	COG0656	L-ascorbic acid biosynthetic process
CWR61_RS11120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWR61_RS11125	COG0583	DNA-binding transcription factor activity
CWR61_RS11140	COG0783	Belongs to the Dps family
CWR61_RS11155	COG0463	Glycosyl transferase, family 2
CWR61_RS11180	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS11195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CWR61_RS11215	COG0300	oxidoreductase activity
CWR61_RS11225	COG0156	8-amino-7-oxononanoate synthase activity
CWR61_RS11230	COG0604	alcohol dehydrogenase
CWR61_RS11230	COG3321	synthase
CWR61_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS11245	COG3842	ATPase activity
CWR61_RS11250	COG0395	ABC-type sugar transport system, permease component
CWR61_RS11255	COG1175	transmembrane transport
CWR61_RS11260	COG1653	transport
CWR61_RS11270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CWR61_RS11280	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS11300	COG1794	racemase activity, acting on amino acids and derivatives
CWR61_RS11305	COG0625	glutathione transferase activity
CWR61_RS11310	COG2133	pyrroloquinoline quinone binding
CWR61_RS11320	COG0697	spore germination
CWR61_RS11325	COG2363	Small membrane protein
CWR61_RS11345	COG1464	Belongs to the NlpA lipoprotein family
CWR61_RS11355	COG0688	phosphatidylethanolamine metabolic process
CWR61_RS11370	COG0095	Lipoate-protein ligase
CWR61_RS11385	COG0625	glutathione transferase activity
CWR61_RS11390	COG0386	Belongs to the glutathione peroxidase family
CWR61_RS11410	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS11430	COG2259	Doxx family
CWR61_RS11445	COG0667	Aldo Keto reductase
CWR61_RS11490	COG1640	4-alpha-glucanotransferase
CWR61_RS11495	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWR61_RS11505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWR61_RS11515	COG0366	Alpha amylase catalytic
CWR61_RS11525	COG0668	transmembrane transport
CWR61_RS11535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWR61_RS11540	COG2204	response regulator
CWR61_RS11545	COG2204	response regulator
CWR61_RS11550	COG0028	Belongs to the TPP enzyme family
CWR61_RS11580	COG5265	(ABC) transporter
CWR61_RS11595	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS11600	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS11605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWR61_RS11615	COG2192	nodulation
CWR61_RS11620	COG1216	Glycosyl transferase, family 2
CWR61_RS11635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR61_RS11670	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS11680	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CWR61_RS11685	COG4575	ribosome binding
CWR61_RS11705	COG1058	Belongs to the CinA family
CWR61_RS11705	COG1546	Belongs to the CinA family
CWR61_RS11720	COG0392	lysyltransferase activity
CWR61_RS11725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR61_RS11730	COG3568	Endonuclease Exonuclease Phosphatase
CWR61_RS11740	COG1695	Transcriptional regulator
CWR61_RS11745	COG2375	cellular response to nickel ion
CWR61_RS11750	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS11760	COG0583	DNA-binding transcription factor activity
CWR61_RS11775	COG1802	Transcriptional regulator
CWR61_RS11785	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS11795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS11800	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS11810	COG0066	3-isopropylmalate dehydratase activity
CWR61_RS11815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWR61_RS11820	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS11825	COG4948	Mandelate Racemase Muconate Lactonizing
CWR61_RS11840	COG2205	protein histidine kinase activity
CWR61_RS11870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR61_RS11880	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CWR61_RS11900	COG4133	protoheme IX ABC transporter activity
CWR61_RS11905	COG3005	denitrification pathway
CWR61_RS11910	COG3043	anaerobic respiration
CWR61_RS11930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS11935	COG0765	amino acid transport
CWR61_RS11940	COG1126	abc transporter atp-binding protein
CWR61_RS11945	COG0330	HflC and HflK could
CWR61_RS11955	COG1454	alcohol dehydrogenase
CWR61_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS11960	COG3706	GGDEF domain
CWR61_RS11960	COG2203	Gaf domain
CWR61_RS11960	COG4251	negative regulation of phosphorylation
CWR61_RS11960	COG5001	Diguanylate cyclase
CWR61_RS11970	COG0583	DNA-binding transcription factor activity
CWR61_RS11975	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS11990	COG0583	DNA-binding transcription factor activity
CWR61_RS12000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR61_RS12010	COG0824	Thioesterase
CWR61_RS12015	COG1454	alcohol dehydrogenase
CWR61_RS12020	COG0183	Belongs to the thiolase family
CWR61_RS12025	COG1024	Enoyl-CoA hydratase
CWR61_RS12025	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS12030	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS12040	COG1024	Enoyl-CoA hydratase
CWR61_RS12045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS12050	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS12055	COG0583	DNA-binding transcription factor activity
CWR61_RS12070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWR61_RS12075	COG0183	Belongs to the thiolase family
CWR61_RS12085	COG1414	Transcriptional regulator
CWR61_RS12090	COG1309	transcriptional regulator
CWR61_RS12135	COG3119	arylsulfatase activity
CWR61_RS12150	COG0625	glutathione transferase activity
CWR61_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS12165	COG0861	Integral membrane protein TerC family
CWR61_RS12195	COG1228	amidohydrolase
CWR61_RS12205	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR61_RS12215	COG1172	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS12225	COG0583	DNA-binding transcription factor activity
CWR61_RS12230	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS12255	COG2188	Transcriptional regulator
CWR61_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS12270	COG1414	Transcriptional regulator
CWR61_RS12275	COG3842	ATPase activity
CWR61_RS12285	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWR61_RS12290	COG0395	ABC-type sugar transport system, permease component
CWR61_RS12305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS12320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWR61_RS12325	COG0439	Biotin carboxylase
CWR61_RS12330	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CWR61_RS12335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS12350	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS12360	COG0583	DNA-binding transcription factor activity
CWR61_RS12370	COG2814	Major facilitator Superfamily
CWR61_RS12390	COG1619	proteins homologs of microcin C7 resistance protein MccF
CWR61_RS12405	COG2084	Dehydrogenase
CWR61_RS12410	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS12420	COG1253	flavin adenine dinucleotide binding
CWR61_RS12435	COG2988	succinylglutamate desuccinylase activity
CWR61_RS12455	COG1716	ATPase activity
CWR61_RS12455	COG5001	Diguanylate cyclase
CWR61_RS12460	COG0861	Integral membrane protein TerC family
CWR61_RS12470	COG1595	DNA-templated transcription, initiation
CWR61_RS12485	COG0076	glutamate decarboxylase activity
CWR61_RS12490	COG2985	domain, Protein
CWR61_RS12495	COG2010	Cytochrome c
CWR61_RS12500	COG3189	MarR family transcriptional regulator
CWR61_RS12510	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS12520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS12520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS12530	COG0028	Belongs to the TPP enzyme family
CWR61_RS12540	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS12545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWR61_RS12550	COG0010	Belongs to the arginase family
CWR61_RS12555	COG1126	abc transporter atp-binding protein
CWR61_RS12560	COG0765	amino acid transport
CWR61_RS12565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS12580	COG0084	hydrolase, TatD family'
CWR61_RS12590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CWR61_RS12595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWR61_RS12620	COG1024	Enoyl-CoA hydratase
CWR61_RS12620	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS12625	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS12635	COG2867	negative regulation of translational initiation
CWR61_RS12640	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CWR61_RS12645	COG3706	GGDEF domain
CWR61_RS12650	COG0330	HflC and HflK could
CWR61_RS12660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWR61_RS12660	COG0519	Catalyzes the synthesis of GMP from XMP
CWR61_RS12675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWR61_RS12680	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CWR61_RS12695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CWR61_RS12700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CWR61_RS12705	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CWR61_RS12710	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR61_RS12715	COG0750	zinc metalloprotease
CWR61_RS12720	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CWR61_RS12725	COG0575	Belongs to the CDS family
CWR61_RS12730	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWR61_RS12735	COG0233	cytoplasmic translational termination
CWR61_RS12740	COG0528	UMP kinase activity
CWR61_RS12745	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CWR61_RS12750	COG0052	Belongs to the universal ribosomal protein uS2 family
CWR61_RS12755	COG0024	Methionine aminopeptidase
CWR61_RS12760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CWR61_RS12790	COG0285	dihydrofolate synthase activity
CWR61_RS12795	COG1334	flagellar protein FlaG
CWR61_RS12820	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CWR61_RS12830	COG1677	Flagellar hook-basal body complex protein FliE
CWR61_RS12840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CWR61_RS12850	COG1157	protein secretion by the type III secretion system
CWR61_RS12865	COG1580	Controls the rotational direction of flagella during chemotaxis
CWR61_RS12885	COG1338	Plays a role in the flagellum-specific transport system
CWR61_RS12900	COG0840	transmembrane signaling receptor activity
CWR61_RS12915	COG0840	transmembrane signaling receptor activity
CWR61_RS12920	COG0840	transmembrane signaling receptor activity
CWR61_RS12930	COG1256	bacterial-type flagellum assembly
CWR61_RS12945	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CWR61_RS12960	COG1749	Flagellar hook protein flgE
CWR61_RS12970	COG1558	bacterial-type flagellum-dependent cell motility
CWR61_RS12975	COG1815	bacterial-type flagellum-dependent cell motility
CWR61_RS13010	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CWR61_RS13015	COG0745	RESPONSE REGULATOR receiver
CWR61_RS13020	COG2201	protein-glutamate methylesterase activity
CWR61_RS13025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CWR61_RS13030	COG0840	transmembrane signaling receptor activity
CWR61_RS13040	COG0643	Histidine kinase
CWR61_RS13040	COG2198	Histidine kinase
CWR61_RS13045	COG0745	RESPONSE REGULATOR receiver
CWR61_RS13050	COG1360	Flagellar Motor Protein
CWR61_RS13075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CWR61_RS13080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR61_RS13085	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWR61_RS13090	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CWR61_RS13100	COG4566	intracellular signal transduction
CWR61_RS13105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWR61_RS13110	COG0339	signal peptide processing
CWR61_RS13115	COG1999	signal sequence binding
CWR61_RS13135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS13145	COG1187	pseudouridine synthase activity
CWR61_RS13150	COG3161	chorismate lyase activity
CWR61_RS13155	COG2814	Major facilitator Superfamily
CWR61_RS13170	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS13175	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS13180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS13185	COG0601	transmembrane transport
CWR61_RS13190	COG0747	negative chemotaxis
CWR61_RS13235	COG0668	transmembrane transport
CWR61_RS13240	COG0165	Argininosuccinate lyase
CWR61_RS13250	COG0789	Transcriptional regulator
CWR61_RS13260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS13265	COG0765	amino acid transport
CWR61_RS13270	COG1126	abc transporter atp-binding protein
CWR61_RS13280	COG2346	COG2346, Truncated hemoglobins
CWR61_RS13340	COG1335	isochorismatase
CWR61_RS13345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS13365	COG2837	iron assimilation
CWR61_RS13400	COG1487	ribonuclease activity
CWR61_RS13420	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS13430	COG0583	DNA-binding transcription factor activity
CWR61_RS13435	COG2814	Major facilitator Superfamily
CWR61_RS13445	COG0501	Belongs to the peptidase M48B family
CWR61_RS13455	COG0583	DNA-binding transcription factor activity
CWR61_RS13465	COG2188	Transcriptional regulator
CWR61_RS13480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWR61_RS13490	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS13495	COG0129	dihydroxy-acid dehydratase activity
CWR61_RS13510	COG0129	dihydroxy-acid dehydratase activity
CWR61_RS13520	COG3622	Belongs to the hyi family
CWR61_RS13525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR61_RS13530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS13545	COG0583	DNA-binding transcription factor activity
CWR61_RS13550	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS13555	COG3246	L-lysine catabolic process to acetate
CWR61_RS13570	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CWR61_RS13575	COG0534	Mate efflux family protein
CWR61_RS13595	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS13600	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS13620	COG0583	DNA-binding transcription factor activity
CWR61_RS13625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWR61_RS13640	COG0697	spore germination
CWR61_RS13655	COG0625	glutathione transferase activity
CWR61_RS13675	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS13680	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS13685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWR61_RS13720	COG2207	Transcriptional regulator
CWR61_RS13785	COG0659	secondary active sulfate transmembrane transporter activity
CWR61_RS13810	COG2169	Transcriptional regulator
CWR61_RS13815	COG5507	3-demethylubiquinone-9 3-methyltransferase
CWR61_RS13820	COG0384	phenazine biosynthesis protein PhzF
CWR61_RS13825	COG0583	DNA-binding transcription factor activity
CWR61_RS13830	COG2733	membrane
CWR61_RS13845	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS13850	COG3284	Transcriptional regulator
CWR61_RS13855	COG0656	L-ascorbic acid biosynthetic process
CWR61_RS13875	COG1131	(ABC) transporter
CWR61_RS13880	COG0842	Transport permease protein
CWR61_RS13885	COG0842	Transport permease protein
CWR61_RS13900	COG1802	Transcriptional regulator
CWR61_RS13920	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS13930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWR61_RS13935	COG2188	Transcriptional regulator
CWR61_RS13950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS13975	COG1609	Transcriptional regulator
CWR61_RS13980	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS13985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS13990	COG0601	transmembrane transport
CWR61_RS13995	COG0747	negative chemotaxis
CWR61_RS14010	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS14030	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CWR61_RS14035	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CWR61_RS14050	COG0625	glutathione transferase activity
CWR61_RS14065	COG2814	Major facilitator Superfamily
CWR61_RS14070	COG0477	Major facilitator Superfamily
CWR61_RS14100	COG1061	Type III restriction enzyme res subunit
CWR61_RS14125	COG0519	Catalyzes the synthesis of GMP from XMP
CWR61_RS14125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CWR61_RS14145	COG2197	response regulator
CWR61_RS14160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR61_RS14180	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS14200	COG3210	domain, Protein
CWR61_RS14200	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR61_RS14200	COG3064	Membrane
CWR61_RS14205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWR61_RS14205	COG0047	phosphoribosylformylglycinamidine synthase activity
CWR61_RS14210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS14215	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS14215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS14220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS14230	COG0613	PHP domain protein
CWR61_RS14240	COG0658	competence protein
CWR61_RS14240	COG2333	competence protein COMEC
CWR61_RS14265	COG0084	hydrolase, TatD family'
CWR61_RS14270	COG1136	(ABC) transporter
CWR61_RS14285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWR61_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS14300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CWR61_RS14310	COG1309	transcriptional regulator
CWR61_RS14315	COG1022	Amp-dependent synthetase and ligase
CWR61_RS14345	COG1024	Enoyl-CoA hydratase
CWR61_RS14350	COG1803	Methylglyoxal synthase
CWR61_RS14360	COG0633	Ferredoxin
CWR61_RS14365	COG0443	Heat shock 70 kDa protein
CWR61_RS14375	COG0316	Belongs to the HesB IscA family
CWR61_RS14380	COG0822	iron-sulfur transferase activity
CWR61_RS14385	COG1104	cysteine desulfurase activity
CWR61_RS14395	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWR61_RS14400	COG0556	nucleotide-excision repair
CWR61_RS14410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CWR61_RS14415	COG3468	outer membrane autotransporter barrel domain protein
CWR61_RS14425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CWR61_RS14440	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS14445	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS14450	COG0183	Belongs to the thiolase family
CWR61_RS14460	COG1024	Enoyl-CoA hydratase
CWR61_RS14475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS14480	COG0583	DNA-binding transcription factor activity
CWR61_RS14485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CWR61_RS14495	COG0740	serine-type endopeptidase activity
CWR61_RS14500	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWR61_RS14510	COG1278	Cold shock
CWR61_RS14520	COG1278	Cold shock
CWR61_RS14550	COG0436	Aminotransferase
CWR61_RS14555	COG2171	N-acyltransferase activity
CWR61_RS14565	COG2890	protein-(glutamine-N5) methyltransferase activity
CWR61_RS14570	COG0488	(ABC) transporter
CWR61_RS14575	COG4771	TonB-dependent receptor
CWR61_RS14580	COG0210	DNA helicase
CWR61_RS14595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWR61_RS14595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWR61_RS14600	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWR61_RS14605	COG0196	riboflavin kinase activity
CWR61_RS14610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CWR61_RS14615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWR61_RS14620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWR61_RS14630	COG1522	sequence-specific DNA binding
CWR61_RS14640	COG0586	Pfam SNARE associated Golgi protein
CWR61_RS14650	COG0756	dUTP diphosphatase activity
CWR61_RS14655	COG1126	abc transporter atp-binding protein
CWR61_RS14660	COG0765	amino acid transport
CWR61_RS14665	COG0765	amino acid transport
CWR61_RS14670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS14680	COG2423	ornithine cyclodeaminase activity
CWR61_RS14685	COG1764	response to oxidative stress
CWR61_RS14700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWR61_RS14715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CWR61_RS14720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWR61_RS14725	COG2197	response regulator
CWR61_RS14735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWR61_RS14785	COG0135	phosphoribosylanthranilate isomerase activity
CWR61_RS14800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS14805	COG0101	tRNA pseudouridine synthase activity
CWR61_RS14815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWR61_RS14840	COG1122	ATPase activity
CWR61_RS14870	COG0437	4 iron, 4 sulfur cluster binding
CWR61_RS14875	COG0243	molybdopterin cofactor binding
CWR61_RS14875	COG3383	formate dehydrogenase (NAD+) activity
CWR61_RS14905	COG0489	protein tyrosine kinase activity
CWR61_RS14910	COG0746	molybdenum cofactor guanylyltransferase activity
CWR61_RS14915	COG0303	'Molybdopterin
CWR61_RS14920	COG1763	Mo-molybdopterin cofactor biosynthetic process
CWR61_RS14930	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CWR61_RS14935	COG3300	MHYT domain
CWR61_RS14935	COG5001	Diguanylate cyclase
CWR61_RS14940	COG2205	protein histidine kinase activity
CWR61_RS14945	COG0745	RESPONSE REGULATOR receiver
CWR61_RS14960	COG1295	ribonuclease BN
CWR61_RS14970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWR61_RS15005	COG4964	Belongs to the GSP D family
CWR61_RS15065	COG0181	hydroxymethylbilane synthase activity
CWR61_RS15070	COG0861	Integral membrane protein TerC family
CWR61_RS15075	COG0861	Integral membrane protein TerC family
CWR61_RS15085	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CWR61_RS15090	COG0045	succinate-CoA ligase (ADP-forming) activity
CWR61_RS15110	COG2137	regulation of response to DNA damage stimulus
CWR61_RS15115	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CWR61_RS15140	COG3842	ATPase activity
CWR61_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS15170	COG0183	Belongs to the thiolase family
CWR61_RS15175	COG0583	DNA-binding transcription factor activity
CWR61_RS15180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS15190	COG2974	May be involved in recombination
CWR61_RS15195	COG0540	Belongs to the ATCase OTCase family
CWR61_RS15235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS15250	COG1522	sequence-specific DNA binding
CWR61_RS15260	COG2367	Beta-lactamase
CWR61_RS15270	COG0456	acetyltransferase
CWR61_RS15355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWR61_RS15355	COG0072	phenylalanine-tRNA ligase activity
CWR61_RS15360	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CWR61_RS15365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CWR61_RS15370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CWR61_RS15390	COG0004	ammonium transporteR
CWR61_RS15395	COG1309	transcriptional regulator
CWR61_RS15400	COG2271	Major facilitator Superfamily
CWR61_RS15430	COG0506	proline dehydrogenase activity
CWR61_RS15430	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CWR61_RS15430	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CWR61_RS15440	COG3008	intermembrane lipid transfer
CWR61_RS15440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWR61_RS15445	COG2995	paraquat-inducible protein a
CWR61_RS15450	COG0542	response to heat
CWR61_RS15455	COG4953	penicillin-binding protein 1C
CWR61_RS15465	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CWR61_RS15470	COG1278	Cold shock
CWR61_RS15480	COG0183	Belongs to the thiolase family
CWR61_RS15485	COG0038	chloride channel
CWR61_RS15490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWR61_RS15500	COG0811	peptide transport
CWR61_RS15505	COG0848	biopolymer transport protein
CWR61_RS15515	COG2835	tetraacyldisaccharide 4'-kinase activity
CWR61_RS15525	COG0563	adenylate kinase activity
CWR61_RS15535	COG0728	peptidoglycan biosynthetic process
CWR61_RS15545	COG0268	Binds directly to 16S ribosomal RNA
CWR61_RS15565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR61_RS15570	COG2186	Transcriptional regulator
CWR61_RS15585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CWR61_RS15595	COG0583	DNA-binding transcription factor activity
CWR61_RS15605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWR61_RS15610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CWR61_RS15615	COG0137	argininosuccinate synthase activity
CWR61_RS15620	COG3158	transport of potassium into the cell
CWR61_RS15625	COG0642	Histidine kinase
CWR61_RS15660	COG0776	regulation of translation
CWR61_RS15665	COG3128	pkhd-type hydroxylase
CWR61_RS15675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWR61_RS15680	COG0557	exoribonuclease II activity
CWR61_RS15705	COG0679	Auxin Efflux Carrier
CWR61_RS15710	COG2391	methyltransferase activity
CWR61_RS15715	COG0069	glutamate synthase activity
CWR61_RS15720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWR61_RS15730	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CWR61_RS15735	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWR61_RS15775	COG3706	GGDEF domain
CWR61_RS15810	COG3909	cytochrome
CWR61_RS15820	COG0625	glutathione transferase activity
CWR61_RS15825	COG0730	response to heat
CWR61_RS15830	COG0482	sulfurtransferase activity
CWR61_RS15835	COG0583	DNA-binding transcription factor activity
CWR61_RS15875	COG2819	hydrolase of the alpha beta superfamily
CWR61_RS15880	COG0247	lactate metabolic process
CWR61_RS15885	COG0277	FAD linked oxidase domain protein
CWR61_RS15890	COG0277	FAD linked oxidase domain protein
CWR61_RS15895	COG0277	FAD linked oxidase domain protein
CWR61_RS15900	COG3064	Membrane
CWR61_RS15900	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CWR61_RS15900	COG3210	domain, Protein
CWR61_RS15905	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWR61_RS15910	COG0312	modulator of DNA gyrase
CWR61_RS15930	COG0308	aminopeptidase N
CWR61_RS15935	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CWR61_RS15955	COG0436	Aminotransferase
CWR61_RS15960	COG3737	Protein of unknown function (DUF498/DUF598)
CWR61_RS15965	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CWR61_RS15970	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CWR61_RS15975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CWR61_RS15985	COG0305	Participates in initiation and elongation during chromosome replication
CWR61_RS16000	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWR61_RS16005	COG2965	DNA replication, synthesis of RNA primer
CWR61_RS16010	COG0360	Binds together with S18 to 16S ribosomal RNA
CWR61_RS16015	COG1469	GTP cyclohydrolase I activity
CWR61_RS16025	COG0142	geranyltranstransferase activity
CWR61_RS16030	COG1722	exodeoxyribonuclease VII activity
CWR61_RS16040	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS16075	COG1840	ABC-type Fe3 transport system, periplasmic component
CWR61_RS16080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CWR61_RS16085	COG1178	ABC-type Fe3 transport system permease component
CWR61_RS16090	COG3842	ATPase activity
CWR61_RS16095	COG0583	DNA-binding transcription factor activity
CWR61_RS16115	COG0501	Belongs to the peptidase M48B family
CWR61_RS16125	COG0697	spore germination
CWR61_RS16135	COG1846	Transcriptional regulator
CWR61_RS16145	COG1566	PFAM secretion protein HlyD family protein
CWR61_RS16150	COG2814	Major facilitator Superfamily
CWR61_RS16155	COG0473	3-isopropylmalate dehydrogenase activity
CWR61_RS16165	COG0747	negative chemotaxis
CWR61_RS16175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS16180	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS16185	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CWR61_RS16210	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS16220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR61_RS16225	COG1115	amino acid carrier protein
CWR61_RS16230	COG0433	COG0433 Predicted ATPase
CWR61_RS16240	COG0151	Belongs to the GarS family
CWR61_RS16250	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWR61_RS16255	COG0799	negative regulation of ribosome biogenesis
CWR61_RS16260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CWR61_RS16265	COG0424	maF-like protein
CWR61_RS16295	COG1530	ribonuclease E activity
CWR61_RS16325	COG1132	(ABC) transporter
CWR61_RS16355	COG2194	sulfuric ester hydrolase activity
CWR61_RS16360	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS16365	COG0463	Glycosyl transferase, family 2
CWR61_RS16370	COG0726	polysaccharide deacetylase
CWR61_RS16375	COG0438	transferase activity, transferring glycosyl groups
CWR61_RS16390	COG1643	Atp-dependent helicase
CWR61_RS16395	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CWR61_RS16395	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CWR61_RS16400	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CWR61_RS16410	COG0704	Plays a role in the regulation of phosphate uptake
CWR61_RS16420	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS16445	COG1177	transmembrane transport
CWR61_RS16450	COG1176	ABC-type spermidine putrescine transport system, permease component I
CWR61_RS16455	COG3842	ATPase activity
CWR61_RS16460	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CWR61_RS16465	COG3642	lipopolysaccharide core region biosynthetic process
CWR61_RS16475	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CWR61_RS16480	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS16490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS16490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS16495	COG3539	Fimbrial protein
CWR61_RS16500	COG3539	Fimbrial protein
CWR61_RS16505	COG3539	Fimbrial protein
CWR61_RS16510	COG3539	Fimbrial protein
CWR61_RS16520	COG2050	protein possibly involved in aromatic compounds catabolism
CWR61_RS16525	COG1024	Enoyl-CoA hydratase
CWR61_RS16530	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS16535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWR61_RS16540	COG2151	metal-sulfur cluster biosynthetic enzyme
CWR61_RS16545	COG3396	Phenylacetate-CoA oxygenase
CWR61_RS16550	COG3460	Phenylacetate-CoA oxygenase
CWR61_RS16555	COG3396	Phenylacetate-CoA oxygenase
CWR61_RS16560	COG3327	negative regulation of DNA-templated transcription, initiation
CWR61_RS16570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CWR61_RS16575	COG0501	Belongs to the peptidase M48B family
CWR61_RS16580	COG1162	GTPase activity
CWR61_RS16585	COG0667	Aldo Keto reductase
CWR61_RS16600	COG0335	large ribosomal subunit rRNA binding
CWR61_RS16630	COG0175	sulfate reduction
CWR61_RS16635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CWR61_RS16640	COG4208	sulfate ABC transporter
CWR61_RS16655	COG0450	alkyl hydroperoxide reductase
CWR61_RS16660	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS16675	COG0123	including yeast histone deacetylase and acetoin utilization protein
CWR61_RS16680	COG2951	lytic endotransglycosylase activity
CWR61_RS16690	COG1555	photosystem II stabilization
CWR61_RS16690	COG1596	polysaccharide export
CWR61_RS16700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CWR61_RS16705	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CWR61_RS16725	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWR61_RS16730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CWR61_RS16735	COG0287	Prephenate dehydrogenase
CWR61_RS16745	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CWR61_RS16760	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CWR61_RS16770	COG2814	Major facilitator Superfamily
CWR61_RS16780	COG0583	DNA-binding transcription factor activity
CWR61_RS16805	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS16820	COG0583	DNA-binding transcription factor activity
CWR61_RS16835	COG0179	Fumarylacetoacetate (FAA) hydrolase
CWR61_RS16860	COG1053	succinate dehydrogenase
CWR61_RS16865	COG2079	MmgE PrpD family protein
CWR61_RS16875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS16890	COG2814	Major facilitator Superfamily
CWR61_RS16895	COG3706	GGDEF domain
CWR61_RS16900	COG0589	response to stress
CWR61_RS16910	COG2951	lytic endotransglycosylase activity
CWR61_RS16915	COG2833	Protein of unknown function (DUF455)
CWR61_RS16930	COG1132	(ABC) transporter
CWR61_RS16935	COG0189	ligase activity
CWR61_RS16935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWR61_RS16940	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWR61_RS16940	COG0189	ligase activity
CWR61_RS16945	COG3237	CsbD-like
CWR61_RS16955	COG2823	Periplasmic or secreted lipoprotein
CWR61_RS16970	COG0672	)-iron permease
CWR61_RS16985	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CWR61_RS16990	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS16995	COG3243	poly(R)-hydroxyalkanoic acid synthase
CWR61_RS17005	COG0564	pseudouridine synthase activity
CWR61_RS17015	COG1199	ATP-dependent helicase activity
CWR61_RS17020	COG2183	response to ionizing radiation
CWR61_RS17045	COG4774	siderophore transport
CWR61_RS17050	COG3712	iron ion homeostasis
CWR61_RS17055	COG1595	DNA-templated transcription, initiation
CWR61_RS17060	COG2175	clavaminate synthase activity
CWR61_RS17070	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS17075	COG0583	DNA-binding transcription factor activity
CWR61_RS17080	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS17085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CWR61_RS17090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR61_RS17095	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWR61_RS17100	COG0567	Dehydrogenase, E1 component
CWR61_RS17105	COG1297	OPT oligopeptide transporter protein
CWR61_RS17110	COG1522	sequence-specific DNA binding
CWR61_RS17120	COG0280	phosphate acetyltransferase
CWR61_RS17120	COG0281	malic enzyme
CWR61_RS17125	COG3539	Fimbrial protein
CWR61_RS17140	COG0372	Belongs to the citrate synthase family
CWR61_RS17145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CWR61_RS17150	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CWR61_RS17155	COG1053	succinate dehydrogenase
CWR61_RS17160	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CWR61_RS17165	COG2009	succinate dehydrogenase
CWR61_RS17170	COG2188	Transcriptional regulator
CWR61_RS17175	COG0039	L-malate dehydrogenase activity
CWR61_RS17195	COG2828	Protein conserved in bacteria
CWR61_RS17200	COG2079	MmgE PrpD family protein
CWR61_RS17205	COG1981	membrane
CWR61_RS17230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR61_RS17240	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CWR61_RS17270	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CWR61_RS17275	COG0148	phosphopyruvate hydratase activity
CWR61_RS17285	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CWR61_RS17290	COG0504	CTP synthase activity
CWR61_RS17310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS17320	COG0747	negative chemotaxis
CWR61_RS17325	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS17330	COG1446	asparaginase
CWR61_RS17375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CWR61_RS17380	COG0697	spore germination
CWR61_RS17385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR61_RS17395	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CWR61_RS17400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CWR61_RS17405	COG0791	NLP P60 protein
CWR61_RS17415	COG0583	DNA-binding transcription factor activity
CWR61_RS17430	COG0583	DNA-binding transcription factor activity
CWR61_RS17440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CWR61_RS17455	COG0670	Belongs to the BI1 family
CWR61_RS17470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CWR61_RS17480	COG1381	Involved in DNA repair and RecF pathway recombination
CWR61_RS17485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CWR61_RS17490	COG0571	ribonuclease III activity
CWR61_RS17495	COG0681	Belongs to the peptidase S26 family
CWR61_RS17505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWR61_RS17530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWR61_RS17535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWR61_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS17550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWR61_RS17555	COG0416	fatty acid biosynthetic process
CWR61_RS17560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CWR61_RS17565	COG1399	metal-binding, possibly nucleic acid-binding protein
CWR61_RS17580	COG3023	N-Acetylmuramoyl-L-alanine amidase
CWR61_RS17585	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CWR61_RS17590	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CWR61_RS17595	COG0546	phosphoglycolate phosphatase activity
CWR61_RS17605	COG1530	ribonuclease E activity
CWR61_RS17615	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CWR61_RS17620	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CWR61_RS17625	COG0159	tryptophan synthase activity
CWR61_RS17630	COG0133	tryptophan synthase activity
CWR61_RS17640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CWR61_RS17645	COG3228	Belongs to the MtfA family
CWR61_RS17655	COG0251	oxidation-reduction process
CWR61_RS17660	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWR61_RS17665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CWR61_RS17680	COG2878	Part of a membrane complex involved in electron transport
CWR61_RS17685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWR61_RS17720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWR61_RS17745	COG1268	BioY protein
CWR61_RS17750	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWR61_RS17755	COG1122	ATPase activity
CWR61_RS17760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWR61_RS17770	COG0271	Belongs to the BolA IbaG family
CWR61_RS17775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWR61_RS17780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CWR61_RS17790	COG1196	nuclear chromosome segregation
CWR61_RS17795	COG0477	Major facilitator Superfamily
CWR61_RS17800	COG1573	uracil-dna glycosylase
CWR61_RS17805	COG1214	PFAM Peptidase M22, glycoprotease
CWR61_RS17820	COG0450	alkyl hydroperoxide reductase
CWR61_RS17825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS17835	COG2223	nitrite transmembrane transporter activity
CWR61_RS17845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CWR61_RS17850	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CWR61_RS17855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWR61_RS17860	COG0560	Phosphoserine phosphatase
CWR61_RS17865	COG0583	DNA-binding transcription factor activity
CWR61_RS17870	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS17875	COG0028	Belongs to the TPP enzyme family
CWR61_RS17885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWR61_RS17890	COG4774	siderophore transport
CWR61_RS17895	COG4774	siderophore transport
CWR61_RS17905	COG1007	ATP synthesis coupled electron transport
CWR61_RS17920	COG0713	ATP synthesis coupled electron transport
CWR61_RS17930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR61_RS17935	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CWR61_RS17940	COG1034	ATP synthesis coupled electron transport
CWR61_RS17950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CWR61_RS17960	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR61_RS17965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR61_RS17970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CWR61_RS17975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR61_RS17995	COG0671	phosphoesterase, PA-phosphatase related
CWR61_RS18005	COG1597	lipid kinase activity
CWR61_RS18010	COG0583	DNA-binding transcription factor activity
CWR61_RS18015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWR61_RS18020	COG1733	regulation of RNA biosynthetic process
CWR61_RS18025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS18030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWR61_RS18045	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CWR61_RS18085	COG3608	succinylglutamate desuccinylase aspartoacylase
CWR61_RS18090	COG0626	cystathionine gamma-synthase activity
CWR61_RS18095	COG0583	DNA-binding transcription factor activity
CWR61_RS18105	COG2301	Belongs to the HpcH HpaI aldolase family
CWR61_RS18125	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS18130	COG2030	dehydratase
CWR61_RS18135	COG0427	acetyl-CoA hydrolase
CWR61_RS18140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS18150	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS18155	COG0165	Argininosuccinate lyase
CWR61_RS18170	COG3799	methylaspartate ammonia-lyase activity
CWR61_RS18180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CWR61_RS18190	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CWR61_RS18195	COG0149	triose-phosphate isomerase activity
CWR61_RS18215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR61_RS18225	COG1185	polyribonucleotide nucleotidyltransferase activity
CWR61_RS18230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CWR61_RS18245	COG1183	phosphatidylcholine synthase activity
CWR61_RS18255	COG0440	acetolactate synthase activity
CWR61_RS18260	COG0028	Belongs to the TPP enzyme family
CWR61_RS18265	COG1289	transmembrane transporter activity
CWR61_RS18275	COG3022	response to hydroperoxide
CWR61_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS18295	COG3486	L-lysine 6-monooxygenase (NADPH) activity
CWR61_RS18325	COG2814	Major facilitator Superfamily
CWR61_RS18340	COG1024	Enoyl-CoA hydratase
CWR61_RS18345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS18375	COG1215	transferase activity, transferring glycosyl groups
CWR61_RS18380	COG0726	polysaccharide deacetylase
CWR61_RS18380	COG1649	PFAM Uncharacterised BCR, COG1649
CWR61_RS18385	COG0457	Tetratricopeptide repeat
CWR61_RS18390	COG3706	GGDEF domain
CWR61_RS18420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWR61_RS18430	COG0747	negative chemotaxis
CWR61_RS18435	COG0601	transmembrane transport
CWR61_RS18460	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CWR61_RS18470	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CWR61_RS18475	COG1674	ftsk spoiiie
CWR61_RS18480	COG0492	ferredoxin-NADP+ reductase activity
CWR61_RS18485	COG1193	negative regulation of DNA recombination
CWR61_RS18495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CWR61_RS18510	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CWR61_RS18515	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CWR61_RS18520	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CWR61_RS18525	COG2205	protein histidine kinase activity
CWR61_RS18530	COG0745	RESPONSE REGULATOR receiver
CWR61_RS18565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWR61_RS18585	COG0612	Peptidase, M16
CWR61_RS18590	COG0484	heat shock protein binding
CWR61_RS18595	COG0443	Heat shock 70 kDa protein
CWR61_RS18605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CWR61_RS18615	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CWR61_RS18620	COG1420	regulation of RNA biosynthetic process
CWR61_RS18630	COG0497	DNA recombination
CWR61_RS18635	COG0735	belongs to the Fur family
CWR61_RS18640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CWR61_RS18650	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CWR61_RS18670	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS18685	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR61_RS18685	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CWR61_RS18690	COG4311	Sarcosine oxidase, delta subunit
CWR61_RS18695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS18705	COG0583	DNA-binding transcription factor activity
CWR61_RS18715	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWR61_RS18735	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CWR61_RS18745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CWR61_RS18745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CWR61_RS18760	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CWR61_RS18765	COG0730	response to heat
CWR61_RS18775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS18785	COG0405	Gamma-glutamyltransferase
CWR61_RS18830	COG0583	DNA-binding transcription factor activity
CWR61_RS18840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CWR61_RS18845	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CWR61_RS18850	COG0167	dihydroorotate dehydrogenase activity
CWR61_RS18865	COG1414	Transcriptional regulator
CWR61_RS18870	COG1058	Belongs to the CinA family
CWR61_RS18870	COG1546	Belongs to the CinA family
CWR61_RS18885	COG0513	Belongs to the DEAD box helicase family
CWR61_RS18915	COG0429	hydrolase of the alpha beta-hydrolase fold
CWR61_RS18925	COG4783	chaperone-mediated protein folding
CWR61_RS18940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR61_RS18955	COG0006	proline dipeptidase activity
CWR61_RS18965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR61_RS18990	COG0632	four-way junction helicase activity
CWR61_RS19010	COG0514	ATP-dependent DNA helicase (RecQ)
CWR61_RS19035	COG1271	oxidase subunit
CWR61_RS19040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWR61_RS19045	COG0850	regulation of cytokinetic process
CWR61_RS19050	COG2894	cell division
CWR61_RS19055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CWR61_RS19070	COG0488	(ABC) transporter
CWR61_RS19095	COG4608	Belongs to the ABC transporter superfamily
CWR61_RS19100	COG0444	Belongs to the ABC transporter superfamily
CWR61_RS19105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS19110	COG0601	transmembrane transport
CWR61_RS19115	COG0747	negative chemotaxis
CWR61_RS19120	COG1215	transferase activity, transferring glycosyl groups
CWR61_RS19125	COG0583	DNA-binding transcription factor activity
CWR61_RS19135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWR61_RS19140	COG0800	Aldolase
CWR61_RS19145	COG1414	Transcriptional regulator
CWR61_RS19150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWR61_RS19160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWR61_RS19180	COG2188	Transcriptional regulator
CWR61_RS19185	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CWR61_RS19190	COG2814	Major facilitator Superfamily
CWR61_RS19200	COG0259	pyridoxamine-phosphate oxidase activity
CWR61_RS19205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CWR61_RS19220	COG0583	DNA-binding transcription factor activity
CWR61_RS19225	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS19235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS19240	COG0405	Gamma-glutamyltransferase
CWR61_RS19250	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS19265	COG0802	atpase or kinase
CWR61_RS19270	COG0860	N-Acetylmuramoyl-L-alanine amidase
CWR61_RS19275	COG0586	Pfam SNARE associated Golgi protein
CWR61_RS19280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CWR61_RS19285	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CWR61_RS19290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CWR61_RS19305	COG0617	tRNA 3'-terminal CCA addition
CWR61_RS19330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS19335	COG2188	Transcriptional regulator
CWR61_RS19345	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CWR61_RS19350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWR61_RS19355	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS19365	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS19370	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS19375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWR61_RS19380	COG2301	Belongs to the HpcH HpaI aldolase family
CWR61_RS19385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS19390	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CWR61_RS19400	COG1024	Enoyl-CoA hydratase
CWR61_RS19410	COG2188	Transcriptional regulator
CWR61_RS19415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CWR61_RS19420	COG0066	3-isopropylmalate dehydratase activity
CWR61_RS19435	COG0752	glycyl-tRNA synthetase alpha subunit
CWR61_RS19440	COG0751	glycine-tRNA ligase activity
CWR61_RS19445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWR61_RS19450	COG0204	Acyl-transferase
CWR61_RS19465	COG0242	peptide deformylase activity
CWR61_RS19470	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS19475	COG0700	Nucleoside recognition
CWR61_RS19480	COG0469	pyruvate kinase activity
CWR61_RS19485	COG1929	Belongs to the glycerate kinase type-1 family
CWR61_RS19495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWR61_RS19500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CWR61_RS19515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CWR61_RS19525	COG2154	pterin-4-alpha-carbinolamine dehydratase
CWR61_RS19540	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS19550	COG0028	Belongs to the TPP enzyme family
CWR61_RS19555	COG3386	PFAM SMP-30 Gluconolaconase
CWR61_RS19565	COG1802	Transcriptional regulator
CWR61_RS19575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CWR61_RS19580	COG0154	amidase activity
CWR61_RS19590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS19595	COG0601	transmembrane transport
CWR61_RS19600	COG0747	negative chemotaxis
CWR61_RS19615	COG0019	diaminopimelate decarboxylase activity
CWR61_RS19625	COG2353	YceI-like domain
CWR61_RS19630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CWR61_RS19670	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS19675	COG1309	transcriptional regulator
CWR61_RS19680	COG2982	Protein involved in outer membrane biogenesis
CWR61_RS19685	COG2818	Glycosylase
CWR61_RS19690	COG0727	PFAM Uncharacterised protein family (UPF0153)
CWR61_RS19710	COG1653	transport
CWR61_RS19715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR61_RS19720	COG3842	ATPase activity
CWR61_RS19725	COG0395	ABC-type sugar transport system, permease component
CWR61_RS19730	COG1175	transmembrane transport
CWR61_RS19750	COG1454	alcohol dehydrogenase
CWR61_RS19765	COG2011	ABC-type metal ion transport system permease component
CWR61_RS19770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWR61_RS19775	COG1501	Belongs to the glycosyl hydrolase 31 family
CWR61_RS19780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CWR61_RS19780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS19790	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS19795	COG1473	amidohydrolase
CWR61_RS19805	COG2855	membrane
CWR61_RS19815	COG2239	Acts as a magnesium transporter
CWR61_RS19830	COG1522	sequence-specific DNA binding
CWR61_RS19835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS19840	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS19860	COG0653	protein targeting
CWR61_RS19865	COG0739	heme binding
CWR61_RS19875	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CWR61_RS19880	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CWR61_RS19890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CWR61_RS19895	COG1181	Belongs to the D-alanine--D-alanine ligase family
CWR61_RS19905	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CWR61_RS19915	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CWR61_RS19920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CWR61_RS19925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWR61_RS19935	COG3116	cell division
CWR61_RS19940	COG0275	rRNA processing
CWR61_RS19945	COG2001	Belongs to the MraZ family
CWR61_RS19955	COG0488	(ABC) transporter
CWR61_RS19960	COG0418	dihydroorotase activity
CWR61_RS19965	COG1473	amidohydrolase
CWR61_RS20015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWR61_RS20020	COG4654	Cytochrome c, class I
CWR61_RS20025	COG0129	dihydroxy-acid dehydratase activity
CWR61_RS20030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CWR61_RS20070	COG2084	Dehydrogenase
CWR61_RS20115	COG0824	Thioesterase
CWR61_RS20120	COG0811	peptide transport
CWR61_RS20125	COG0848	biopolymer transport protein
CWR61_RS20135	COG0823	Involved in the tonB-independent uptake of proteins
CWR61_RS20150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWR61_RS20155	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CWR61_RS20160	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS20175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS20195	COG0318	PFAM AMP-dependent synthetase and ligase
CWR61_RS20200	COG0183	Belongs to the thiolase family
CWR61_RS20205	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS20210	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS20215	COG0583	DNA-binding transcription factor activity
CWR61_RS20220	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS20225	COG1024	Enoyl-CoA hydratase
CWR61_RS20235	COG1253	flavin adenine dinucleotide binding
CWR61_RS20240	COG1285	pathogenesis
CWR61_RS20245	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CWR61_RS20260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWR61_RS20265	COG0697	spore germination
CWR61_RS20295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CWR61_RS20300	COG0463	Glycosyl transferase, family 2
CWR61_RS20310	COG0786	glutamate:sodium symporter activity
CWR61_RS20320	COG2031	fatty acid transporter
CWR61_RS20335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CWR61_RS20340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CWR61_RS20345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWR61_RS20350	COG0328	RNA-DNA hybrid ribonuclease activity
CWR61_RS20355	COG2226	methyltransferase
CWR61_RS20360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWR61_RS20365	COG0741	lytic transglycosylase activity
CWR61_RS20365	COG1388	LysM domain
CWR61_RS20380	COG2979	Protein of unknown function (DUF533)
CWR61_RS20450	COG0154	amidase activity
CWR61_RS20460	COG2816	NAD+ diphosphatase activity
CWR61_RS20465	COG1309	transcriptional regulator
CWR61_RS20470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS20485	COG1024	Enoyl-CoA hydratase
CWR61_RS20500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS20515	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS20530	COG3119	arylsulfatase activity
CWR61_RS20555	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CWR61_RS20560	COG0830	nickel cation binding
CWR61_RS20570	COG0804	urea catabolic process
CWR61_RS20575	COG0832	Belongs to the urease beta subunit family
CWR61_RS20585	COG0831	urea catabolic process
CWR61_RS20590	COG0829	nickel cation binding
CWR61_RS20630	COG2188	Transcriptional regulator
CWR61_RS20635	COG3799	methylaspartate ammonia-lyase activity
CWR61_RS20655	COG2719	SpoVR family
CWR61_RS20660	COG2718	Belongs to the UPF0229 family
CWR61_RS20665	COG2766	serine protein kinase
CWR61_RS20670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWR61_RS20670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CWR61_RS20680	COG4977	sequence-specific DNA binding
CWR61_RS20685	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWR61_RS20690	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CWR61_RS20700	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CWR61_RS20715	COG0316	Belongs to the HesB IscA family
CWR61_RS20725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CWR61_RS20730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CWR61_RS20735	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWR61_RS20740	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CWR61_RS20745	COG0312	modulator of DNA gyrase
CWR61_RS20765	COG1116	anion transmembrane transporter activity
CWR61_RS20770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS20775	COG1335	isochorismatase
CWR61_RS20780	COG0346	lactoylglutathione lyase activity
CWR61_RS20785	COG0513	Belongs to the DEAD box helicase family
CWR61_RS20790	COG3069	C4-dicarboxylate transmembrane transporter activity
CWR61_RS20795	COG1802	Transcriptional regulator
CWR61_RS20800	COG1042	CoA-binding domain protein
CWR61_RS20800	COG0045	succinate-CoA ligase (ADP-forming) activity
CWR61_RS20800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWR61_RS20805	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWR61_RS20820	COG1522	sequence-specific DNA binding
CWR61_RS20855	COG1696	Membrane protein involved in D-alanine export
CWR61_RS20880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CWR61_RS20890	COG2264	protein methyltransferase activity
CWR61_RS20895	COG0439	Biotin carboxylase
CWR61_RS20900	COG0511	ligase activity, forming carbon-carbon bonds
CWR61_RS20905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CWR61_RS20910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR61_RS20915	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CWR61_RS20920	COG3150	esterase
CWR61_RS20925	COG0557	exoribonuclease II activity
CWR61_RS20935	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CWR61_RS20940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWR61_RS20965	COG0540	Belongs to the ATCase OTCase family
CWR61_RS20975	COG1678	Uncharacterized ACR, COG1678
CWR61_RS20985	COG0351	phosphomethylpyrimidine kinase
CWR61_RS20990	COG0352	thiamine-phosphate diphosphorylase activity
CWR61_RS20995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CWR61_RS21020	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS21025	COG1024	Enoyl-CoA hydratase
CWR61_RS21030	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS21090	COG0494	nUDIX hydrolase
CWR61_RS21115	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CWR61_RS21125	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CWR61_RS21140	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CWR61_RS21145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CWR61_RS21175	COG1126	abc transporter atp-binding protein
CWR61_RS21180	COG0765	amino acid transport
CWR61_RS21185	COG4597	amino acid ABC transporter
CWR61_RS21190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS21195	COG2884	Cell division ATP-binding protein ftsE
CWR61_RS21200	COG2177	Part of the ABC transporter FtsEX involved in
CWR61_RS21205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CWR61_RS21215	COG1194	a g-specific adenine glycosylase
CWR61_RS21225	COG2226	methyltransferase
CWR61_RS21235	COG4206	TonB-dependent receptor
CWR61_RS21240	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CWR61_RS21245	COG2022	thiamine diphosphate biosynthetic process
CWR61_RS21250	COG0351	phosphomethylpyrimidine kinase
CWR61_RS21255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CWR61_RS21265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CWR61_RS21275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CWR61_RS21290	COG2226	methyltransferase
CWR61_RS21295	COG0745	RESPONSE REGULATOR receiver
CWR61_RS21300	COG5002	protein histidine kinase activity
CWR61_RS21310	COG5002	protein histidine kinase activity
CWR61_RS21320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR61_RS21335	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CWR61_RS21340	COG1984	allophanate hydrolase subunit 2
CWR61_RS21355	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS21365	COG1024	Enoyl-CoA hydratase
CWR61_RS21380	COG1802	Transcriptional regulator
CWR61_RS21390	COG1238	metal cluster binding
CWR61_RS21395	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWR61_RS21400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR61_RS21420	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CWR61_RS21425	COG4988	ABC transporter
CWR61_RS21435	COG1294	oxidase, subunit
CWR61_RS21450	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CWR61_RS21460	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CWR61_RS21475	COG1137	ATPase activity
CWR61_RS21480	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CWR61_RS21495	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CWR61_RS21495	COG2010	Cytochrome c
CWR61_RS21505	COG1660	Displays ATPase and GTPase activities
CWR61_RS21515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWR61_RS21530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CWR61_RS21535	COG2823	Periplasmic or secreted lipoprotein
CWR61_RS21540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWR61_RS21550	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CWR61_RS21560	COG1309	transcriptional regulator
CWR61_RS21565	COG0471	metal ion transport
CWR61_RS21570	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR61_RS21575	COG0772	Belongs to the SEDS family
CWR61_RS21580	COG0768	penicillin binding
CWR61_RS21590	COG1792	Involved in formation and maintenance of cell shape
CWR61_RS21595	COG1077	Cell shape determining protein MreB Mrl
CWR61_RS21600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWR61_RS21605	COG0154	amidase activity
CWR61_RS21610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWR61_RS21615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CWR61_RS21620	COG0708	Exodeoxyribonuclease III
CWR61_RS21625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWR61_RS21630	COG2860	membrane
CWR61_RS21640	COG0583	DNA-binding transcription factor activity
CWR61_RS21645	COG0473	3-isopropylmalate dehydrogenase activity
CWR61_RS21650	COG3391	amine dehydrogenase activity
CWR61_RS21670	COG0583	DNA-binding transcription factor activity
CWR61_RS21675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CWR61_RS21680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWR61_RS21685	COG0765	amino acid transport
CWR61_RS21690	COG0765	amino acid transport
CWR61_RS21695	COG1126	abc transporter atp-binding protein
CWR61_RS21700	COG1794	racemase activity, acting on amino acids and derivatives
CWR61_RS21705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR61_RS21710	COG2223	nitrite transmembrane transporter activity
CWR61_RS21715	COG2813	Specifically methylates the guanine in position
CWR61_RS21715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR61_RS21720	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CWR61_RS21725	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CWR61_RS21750	COG2918	glutathione biosynthetic process
CWR61_RS21770	COG0583	DNA-binding transcription factor activity
CWR61_RS21775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CWR61_RS21780	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CWR61_RS21815	COG0154	amidase activity
CWR61_RS21825	COG1414	Transcriptional regulator
CWR61_RS21835	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS21835	COG1024	Enoyl-CoA hydratase
CWR61_RS21845	COG2132	Multicopper oxidase
CWR61_RS21865	COG1250	3-hydroxyacyl-CoA dehydrogenase
CWR61_RS21890	COG1024	Enoyl-CoA hydratase
CWR61_RS21900	COG1024	Enoyl-CoA hydratase
CWR61_RS21905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWR61_RS21915	COG0747	negative chemotaxis
CWR61_RS21925	COG0601	transmembrane transport
CWR61_RS21930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS21935	COG0444	Belongs to the ABC transporter superfamily
CWR61_RS21940	COG4608	Belongs to the ABC transporter superfamily
CWR61_RS21950	COG2195	Cleaves the N-terminal amino acid of tripeptides
CWR61_RS21955	COG0210	DNA helicase
CWR61_RS21960	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWR61_RS21965	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CWR61_RS21975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CWR61_RS21985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CWR61_RS21995	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CWR61_RS22010	COG0356	it plays a direct role in the translocation of protons across the membrane
CWR61_RS22025	COG1024	Enoyl-CoA hydratase
CWR61_RS22030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWR61_RS22045	COG0037	tRNA processing
CWR61_RS22050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CWR61_RS22060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CWR61_RS22065	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CWR61_RS22070	COG2967	ApaG domain
CWR61_RS22075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CWR61_RS22080	COG0546	phosphoglycolate phosphatase activity
CWR61_RS22090	COG0512	Glutamine amidotransferase of anthranilate synthase
CWR61_RS22105	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS22125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CWR61_RS22135	COG1607	acyl-coa hydrolase
CWR61_RS22170	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS22180	COG3069	C4-dicarboxylate transmembrane transporter activity
CWR61_RS22190	COG1802	Transcriptional regulator
CWR61_RS22220	COG1595	DNA-templated transcription, initiation
CWR61_RS22225	COG3712	iron ion homeostasis
CWR61_RS22235	COG3720	iron ion transport
CWR61_RS22240	COG4558	Periplasmic binding protein
CWR61_RS22245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWR61_RS22250	COG1120	ATPase activity
CWR61_RS22255	COG1683	Conserved Protein
CWR61_RS22285	COG3064	Membrane
CWR61_RS22290	COG0583	DNA-binding transcription factor activity
CWR61_RS22300	COG1234	tRNA 3'-trailer cleavage
CWR61_RS22310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CWR61_RS22315	COG1802	Transcriptional regulator
CWR61_RS22330	COG3842	ATPase activity
CWR61_RS22340	COG1177	transmembrane transport
CWR61_RS22350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWR61_RS22360	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR61_RS22365	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS22390	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22400	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22415	COG2186	Transcriptional regulator
CWR61_RS22420	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS22425	COG4948	Mandelate Racemase Muconate Lactonizing
CWR61_RS22445	COG1053	succinate dehydrogenase
CWR61_RS22450	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWR61_RS22475	COG0411	ABC transporter
CWR61_RS22480	COG0559	Belongs to the binding-protein-dependent transport system permease family
CWR61_RS22485	COG0683	leucine binding
CWR61_RS22505	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWR61_RS22510	COG1024	Enoyl-CoA hydratase
CWR61_RS22515	COG0022	dehydrogenase e1 component
CWR61_RS22520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWR61_RS22545	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS22550	COG1024	Enoyl-CoA hydratase
CWR61_RS22555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CWR61_RS22575	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS22580	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS22595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWR61_RS22610	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CWR61_RS22615	COG1984	allophanate hydrolase subunit 2
CWR61_RS22620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CWR61_RS22625	COG0747	negative chemotaxis
CWR61_RS22630	COG0601	transmembrane transport
CWR61_RS22635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS22640	COG4172	Belongs to the ABC transporter superfamily
CWR61_RS22670	COG0439	Biotin carboxylase
CWR61_RS22685	COG0709	Synthesizes selenophosphate from selenide and ATP
CWR61_RS22690	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CWR61_RS22700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS22710	COG0604	alcohol dehydrogenase
CWR61_RS22720	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS22730	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS22740	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22745	COG1024	Enoyl-CoA hydratase
CWR61_RS22750	COG0446	pyridine nucleotide-disulphide oxidoreductase
CWR61_RS22750	COG1902	pentaerythritol trinitrate reductase activity
CWR61_RS22755	COG1024	Enoyl-CoA hydratase
CWR61_RS22760	COG1846	Transcriptional regulator
CWR61_RS22775	COG4771	TonB-dependent receptor
CWR61_RS22790	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS22795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS22800	COG0183	Belongs to the thiolase family
CWR61_RS22805	COG2030	dehydratase
CWR61_RS22810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS22850	COG3842	ATPase activity
CWR61_RS22860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CWR61_RS22870	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CWR61_RS22875	COG0583	DNA-binding transcription factor activity
CWR61_RS22890	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS22900	COG0277	FAD linked oxidase domain protein
CWR61_RS22905	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS22910	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS22935	COG2072	flavoprotein involved in K transport
CWR61_RS22940	COG0604	alcohol dehydrogenase
CWR61_RS22955	COG1024	Enoyl-CoA hydratase
CWR61_RS22980	COG1522	sequence-specific DNA binding
CWR61_RS22990	COG3708	Transcriptional regulator
CWR61_RS22990	COG2207	Transcriptional regulator
CWR61_RS23005	COG2814	Major facilitator Superfamily
CWR61_RS23010	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CWR61_RS23030	COG1999	signal sequence binding
CWR61_RS23075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CWR61_RS23095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWR61_RS23100	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWR61_RS23110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CWR61_RS23115	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CWR61_RS23125	COG0067	glutamate synthase
CWR61_RS23125	COG0069	glutamate synthase activity
CWR61_RS23125	COG0070	glutamate synthase
CWR61_RS23135	COG3047	cAMP biosynthetic process
CWR61_RS23145	COG1127	ABC transporter
CWR61_RS23150	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CWR61_RS23155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CWR61_RS23160	COG2853	Lipoprotein
CWR61_RS23170	COG1131	(ABC) transporter
CWR61_RS23175	COG0842	Transport permease protein
CWR61_RS23185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWR61_RS23195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CWR61_RS23200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CWR61_RS23205	COG0131	Imidazoleglycerol-phosphate dehydratase
CWR61_RS23215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CWR61_RS23220	COG0107	imidazoleglycerol-phosphate synthase activity
CWR61_RS23230	COG0140	phosphoribosyl-ATP diphosphatase activity
CWR61_RS23235	COG0537	adenosine 5'-monophosphoramidase activity
CWR61_RS23240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWR61_RS23245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CWR61_RS23265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWR61_RS23270	COG1970	mechanosensitive ion channel activity
CWR61_RS23275	COG0723	plastoquinol--plastocyanin reductase activity
CWR61_RS23280	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CWR61_RS23285	COG2857	Cytochrome c1
CWR61_RS23290	COG0625	glutathione transferase activity
CWR61_RS23295	COG2969	positive regulation of protein catabolic process
CWR61_RS23325	COG0583	DNA-binding transcription factor activity
CWR61_RS23330	COG0492	ferredoxin-NADP+ reductase activity
CWR61_RS23350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS23360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CWR61_RS23375	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS23410	COG3702	type iv secretory pathway
CWR61_RS23415	COG3451	type IV secretory pathway VirB4
CWR61_RS23430	COG3736	Type IV secretory pathway, component VirB8
CWR61_RS23440	COG2948	multi-organism process
CWR61_RS23445	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
CWR61_RS23455	COG0697	spore germination
CWR61_RS23475	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWR61_RS23485	COG0601	transmembrane transport
CWR61_RS23490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWR61_RS23500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CWR61_RS23510	COG0513	Belongs to the DEAD box helicase family
CWR61_RS23515	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS23520	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CWR61_RS23540	COG0583	DNA-binding transcription factor activity
CWR61_RS23550	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CWR61_RS23560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CWR61_RS23565	COG0154	amidase activity
CWR61_RS23570	COG1609	Transcriptional regulator
CWR61_RS23590	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CWR61_RS23595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CWR61_RS23600	COG3842	ATPase activity
CWR61_RS23605	COG1653	transport
CWR61_RS23610	COG1175	transmembrane transport
CWR61_RS23615	COG0395	ABC-type sugar transport system, permease component
CWR61_RS23630	COG0018	arginyl-trna synthetase
CWR61_RS23650	COG1280	lysine exporter protein (LysE YggA)
CWR61_RS23665	COG1960	acyl-CoA dehydrogenase activity
CWR61_RS23670	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CWR61_RS23675	COG0183	Belongs to the thiolase family
CWR61_RS23680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CWR61_RS23695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CWR61_RS23700	COG3181	Tripartite tricarboxylate transporter family receptor
CWR61_RS23710	COG2358	TRAP transporter, solute receptor (TAXI family
CWR61_RS23720	COG1629	transport
CWR61_RS23725	COG2922	Belongs to the Smg family
CWR61_RS23730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CWR61_RS23750	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR61_RS23755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS23760	COG1028	Short-chain dehydrogenase reductase Sdr
CWR61_RS23765	COG1012	belongs to the aldehyde dehydrogenase family
CWR61_RS23775	COG0028	Belongs to the TPP enzyme family
CWR61_RS23780	COG1522	sequence-specific DNA binding
CWR61_RS23785	COG3781	membrane
CWR61_RS23815	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CWR61_RS23840	COG1304	FMN binding
CWR61_RS23855	COG0154	amidase activity
CWR61_RS23860	COG1414	Transcriptional regulator
CWR61_RS23885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CWR61_RS23890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CWR61_RS23895	COG0594	ribonuclease P activity
CWR61_RS23900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CWR61_RS23905	COG0706	membrane insertase activity
CWR61_RS23910	COG0753	catalase activity
CWR61_RS23915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWR61_RS23920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CWR61_RS23930	COG2175	clavaminate synthase activity
CWR61_RS23935	COG1473	amidohydrolase
CWR61_RS23940	COG4608	Belongs to the ABC transporter superfamily
CWR61_RS23955	COG0601	transmembrane transport
CWR61_RS23960	COG0747	negative chemotaxis
CWR61_RS24000	COG0436	Aminotransferase
CWR61_RS24005	COG1278	Cold shock