locus-tag	class	description
BB_RS00005	COG0445	tRNA wobble uridine modification
BB_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
BB_RS00015	COG1192	Involved in chromosome partitioning
BB_RS00025	COG1475	DNA binding
BB_RS00030	COG0252	asparaginase activity
BB_RS00050	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB_RS00060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB_RS00075	COG0081	regulation of translation
BB_RS00080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BB_RS00085	COG0222	ribosome binding
BB_RS00090	COG0085	RNA polymerase activity
BB_RS00095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BB_RS00130	COG1230	cation diffusion facilitator family transporter
BB_RS00140	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BB_RS00145	COG0049	tRNA binding
BB_RS00150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BB_RS00155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BB_RS00160	COG0051	transcription antitermination factor activity, RNA binding
BB_RS00165	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BB_RS00175	COG0089	rRNA binding
BB_RS00180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BB_RS00190	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BB_RS00195	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BB_RS00200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BB_RS00205	COG0255	Belongs to the universal ribosomal protein uL29 family
BB_RS00210	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BB_RS00230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BB_RS00235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BB_RS00240	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BB_RS00245	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BB_RS00250	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BB_RS00260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BB_RS00265	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BB_RS00270	COG1841	ribosomal large subunit assembly
BB_RS00275	COG0200	Binds to the 23S rRNA
BB_RS00280	COG0201	protein transport
BB_RS00285	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB_RS00290	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB_RS00295	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BB_RS00300	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BB_RS00305	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BB_RS00310	COG0202	RNA polymerase activity
BB_RS00315	COG0203	ribosomal protein L17
BB_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
BB_RS00325	COG1324	tolerance protein
BB_RS00330	COG4232	protein-disulfide reductase activity
BB_RS00345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BB_RS00355	COG1333	cytochrome c biogenesis protein
BB_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB_RS00380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BB_RS00385	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BB_RS00390	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BB_RS00405	COG2814	Major facilitator Superfamily
BB_RS00410	COG0629	single-stranded DNA binding
BB_RS00445	COG0402	S-adenosylhomocysteine deaminase activity
BB_RS00455	COG0438	transferase activity, transferring glycosyl groups
BB_RS00475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS00505	COG2186	Transcriptional regulator
BB_RS00525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS00530	COG1956	GAF domain-containing protein
BB_RS00535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS00560	COG0531	amino acid
BB_RS00595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BB_RS00600	COG3568	Endonuclease Exonuclease Phosphatase
BB_RS00605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB_RS00615	COG0477	Major facilitator Superfamily
BB_RS00625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB_RS00635	COG0367	asparagine synthase
BB_RS00655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB_RS00695	COG0367	asparagine synthase
BB_RS00700	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BB_RS00725	COG0367	asparagine synthase
BB_RS00735	COG0438	transferase activity, transferring glycosyl groups
BB_RS00755	COG0438	transferase activity, transferring glycosyl groups
BB_RS00760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BB_RS00765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BB_RS00795	COG0859	PFAM glycosyl transferase family 9
BB_RS00815	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BB_RS00825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB_RS00830	COG1127	ABC transporter
BB_RS00850	COG1686	Belongs to the peptidase S11 family
BB_RS00865	COG0321	lipoyl(octanoyl) transferase activity
BB_RS00870	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BB_RS00890	COG2096	Adenosyltransferase
BB_RS00900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BB_RS00915	COG0523	cobalamin synthesis protein
BB_RS00920	COG0735	belongs to the Fur family
BB_RS00925	COG1121	(ABC) transporter
BB_RS00935	COG0803	Belongs to the bacterial solute-binding protein 9 family
BB_RS00945	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BB_RS00955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB_RS00965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB_RS00970	COG1560	Kdo2-lipid A biosynthetic process
BB_RS00980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BB_RS01000	COG1950	PFAM Membrane protein of
BB_RS01010	COG0583	DNA-binding transcription factor activity
BB_RS01020	COG0477	Major facilitator Superfamily
BB_RS01035	COG0617	tRNA 3'-terminal CCA addition
BB_RS01045	COG0513	Belongs to the DEAD box helicase family
BB_RS01050	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BB_RS01055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB_RS01060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB_RS01075	COG0735	belongs to the Fur family
BB_RS01095	COG0438	transferase activity, transferring glycosyl groups
BB_RS01120	COG0640	Transcriptional regulator
BB_RS01180	COG0583	DNA-binding transcription factor activity
BB_RS01195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB_RS01200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS01205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS01220	COG0758	DNA mediated transformation
BB_RS01225	COG1522	sequence-specific DNA binding
BB_RS01235	COG0242	peptide deformylase activity
BB_RS01240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BB_RS01250	COG0546	phosphoglycolate phosphatase activity
BB_RS01270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB_RS01275	COG1942	4-Oxalocrotonate Tautomerase
BB_RS01280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS01300	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB_RS01310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB_RS01310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB_RS01320	COG5000	phosphorelay sensor kinase activity
BB_RS01325	COG2204	response regulator
BB_RS01350	COG2068	MobA-Related Protein
BB_RS01360	COG3473	Maleate cis-trans isomerase
BB_RS01365	COG0596	Alpha beta hydrolase
BB_RS01370	COG2309	aminopeptidase activity
BB_RS01375	COG1335	isochorismatase
BB_RS01400	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS01425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB_RS01430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS01450	COG2226	methyltransferase
BB_RS01465	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS01470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BB_RS01475	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BB_RS01480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB_RS01485	COG1054	Belongs to the UPF0176 family
BB_RS01490	COG0588	phosphoglycerate mutase activity
BB_RS01495	COG4942	peptidase
BB_RS01500	COG0793	Belongs to the peptidase S41A family
BB_RS01505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB_RS01525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB_RS01555	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BB_RS01560	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BB_RS01565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BB_RS01570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BB_RS01580	COG0142	geranyltranstransferase activity
BB_RS01590	COG0583	DNA-binding transcription factor activity
BB_RS01600	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
BB_RS01605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS01620	COG2994	toxin metabolic process
BB_RS01630	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BB_RS01635	COG2274	protein secretion by the type I secretion system
BB_RS01640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS01645	COG1538	Outer membrane efflux protein
BB_RS01660	COG0765	amino acid transport
BB_RS01665	COG0765	amino acid transport
BB_RS01670	COG1126	abc transporter atp-binding protein
BB_RS01690	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS01700	COG1802	Transcriptional regulator
BB_RS01710	COG1802	Transcriptional regulator
BB_RS01720	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS01730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS01750	COG0028	Belongs to the TPP enzyme family
BB_RS01760	COG0583	DNA-binding transcription factor activity
BB_RS01765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS01770	COG2301	Belongs to the HpcH HpaI aldolase family
BB_RS01775	COG2188	Transcriptional regulator
BB_RS01820	COG0583	DNA-binding transcription factor activity
BB_RS01825	COG1024	Enoyl-CoA hydratase
BB_RS01860	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS01875	COG1902	pentaerythritol trinitrate reductase activity
BB_RS01900	COG0745	RESPONSE REGULATOR receiver
BB_RS01925	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BB_RS01930	COG2890	protein-(glutamine-N5) methyltransferase activity
BB_RS01935	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BB_RS01945	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS01980	COG1464	Belongs to the NlpA lipoprotein family
BB_RS02015	COG4211	Belongs to the binding-protein-dependent transport system permease family
BB_RS02020	COG0583	DNA-binding transcription factor activity
BB_RS02025	COG0683	leucine binding
BB_RS02030	COG0154	amidase activity
BB_RS02035	COG0288	reversible hydration of carbon dioxide
BB_RS02055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB_RS02070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BB_RS02080	COG1414	Transcriptional regulator
BB_RS02085	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS02090	COG2031	fatty acid transporter
BB_RS02095	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS02105	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB_RS02110	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BB_RS02120	COG4257	antibiotic catabolic process
BB_RS02125	COG2808	Putative FMN-binding domain
BB_RS02130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB_RS02135	COG0747	negative chemotaxis
BB_RS02140	COG0657	acetylesterase activity
BB_RS02150	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB_RS02155	COG2207	Transcriptional regulator
BB_RS02165	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BB_RS02170	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BB_RS02180	COG1538	Outer membrane efflux protein
BB_RS02195	COG0583	DNA-binding transcription factor activity
BB_RS02200	COG0628	permease
BB_RS02210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BB_RS02215	COG0251	oxidation-reduction process
BB_RS02225	COG0330	HflC and HflK could
BB_RS02230	COG3422	double-strand break repair
BB_RS02245	COG0583	DNA-binding transcription factor activity
BB_RS02275	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02280	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS02285	COG1414	Transcriptional regulator
BB_RS02290	COG1024	Enoyl-CoA hydratase
BB_RS02295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS02305	COG0604	alcohol dehydrogenase
BB_RS02310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02315	COG0583	DNA-binding transcription factor activity
BB_RS02325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02340	COG0251	oxidation-reduction process
BB_RS02345	COG1017	nitric oxide dioxygenase activity
BB_RS02345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB_RS02350	COG2031	fatty acid transporter
BB_RS02370	COG1278	Cold shock
BB_RS02375	COG0583	DNA-binding transcription factor activity
BB_RS02385	COG3119	arylsulfatase activity
BB_RS02400	COG1228	amidohydrolase
BB_RS02405	COG0523	cobalamin synthesis protein
BB_RS02410	COG1819	glycosyl
BB_RS02485	COG0326	Molecular chaperone. Has ATPase activity
BB_RS02490	COG0625	glutathione transferase activity
BB_RS02505	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BB_RS02510	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BB_RS02515	COG1652	LysM domain
BB_RS02540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02570	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS02610	COG0583	DNA-binding transcription factor activity
BB_RS02615	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02625	COG1024	Enoyl-CoA hydratase
BB_RS02630	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02655	COG0028	Belongs to the TPP enzyme family
BB_RS02660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02665	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS02665	COG1024	Enoyl-CoA hydratase
BB_RS02670	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02675	COG1414	Transcriptional regulator
BB_RS02695	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS02700	COG1609	Transcriptional regulator
BB_RS02730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS02735	COG1024	Enoyl-CoA hydratase
BB_RS02750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02755	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02760	COG0583	DNA-binding transcription factor activity
BB_RS02775	COG1960	acyl-CoA dehydrogenase activity
BB_RS02785	COG0066	3-isopropylmalate dehydratase activity
BB_RS02790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB_RS02795	COG0583	DNA-binding transcription factor activity
BB_RS02800	COG1053	succinate dehydrogenase
BB_RS02800	COG3976	FMN-binding domain protein
BB_RS02835	COG0683	leucine binding
BB_RS02840	COG1309	transcriptional regulator
BB_RS02860	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS02865	COG1960	acyl-CoA dehydrogenase activity
BB_RS02870	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS02875	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS02885	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BB_RS02895	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
BB_RS02900	COG1053	succinate dehydrogenase
BB_RS02910	COG2030	dehydratase
BB_RS02920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS02930	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS02955	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS02975	COG1902	pentaerythritol trinitrate reductase activity
BB_RS02975	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB_RS02990	COG0427	acetyl-CoA hydrolase
BB_RS02995	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS03010	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BB_RS03015	COG1960	acyl-CoA dehydrogenase activity
BB_RS03030	COG0183	Belongs to the thiolase family
BB_RS03035	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB_RS03045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS03050	COG0583	DNA-binding transcription factor activity
BB_RS03055	COG1960	acyl-CoA dehydrogenase activity
BB_RS03070	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BB_RS03095	COG1309	transcriptional regulator
BB_RS03105	COG1024	Enoyl-CoA hydratase
BB_RS03125	COG1024	Enoyl-CoA hydratase
BB_RS03130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS03135	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03140	COG1454	alcohol dehydrogenase
BB_RS03145	COG1024	Enoyl-CoA hydratase
BB_RS03165	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS03170	COG0431	NADPH-dependent FMN reductase
BB_RS03175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS03180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB_RS03195	COG1414	Transcriptional regulator
BB_RS03200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB_RS03205	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS03210	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03215	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS03225	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS03240	COG1960	acyl-CoA dehydrogenase activity
BB_RS03275	COG1960	acyl-CoA dehydrogenase activity
BB_RS03280	COG1024	Enoyl-CoA hydratase
BB_RS03285	COG0183	Belongs to the thiolase family
BB_RS03290	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03305	COG0583	DNA-binding transcription factor activity
BB_RS03310	COG2267	carboxylic ester hydrolase activity
BB_RS03325	COG0625	glutathione transferase activity
BB_RS03330	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03340	COG2186	Transcriptional regulator
BB_RS03345	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS03350	COG0626	cystathionine gamma-synthase activity
BB_RS03390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS03395	COG0436	Aminotransferase
BB_RS03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS03405	COG0765	amino acid transport
BB_RS03415	COG1473	amidohydrolase
BB_RS03420	COG1414	Transcriptional regulator
BB_RS03430	COG0154	amidase activity
BB_RS03490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS03500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB_RS03505	COG3135	benzoate transporter
BB_RS03530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB_RS03535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS03540	COG1335	isochorismatase
BB_RS03555	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS03590	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03595	COG0633	Ferredoxin
BB_RS03595	COG0543	2 iron, 2 sulfur cluster binding
BB_RS03600	COG4638	Rieske (2fe-2S)
BB_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS03620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB_RS03640	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS03645	COG3384	dioxygenase
BB_RS03655	COG3971	2-oxopent-4-enoate hydratase activity
BB_RS03710	COG1024	Enoyl-CoA hydratase
BB_RS03715	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS03720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS03735	COG1960	acyl-CoA dehydrogenase activity
BB_RS03780	COG0183	Belongs to the thiolase family
BB_RS03785	COG2030	dehydratase
BB_RS03795	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS03805	COG1414	Transcriptional regulator
BB_RS03810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS03855	COG1459	type II secretion system
BB_RS03860	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BB_RS03865	COG3267	Type II secretory pathway component ExeA
BB_RS03865	COG3409	Peptidoglycan-binding domain 1 protein
BB_RS03875	COG1450	Type ii and iii secretion system protein
BB_RS03940	COG5444	nuclease activity
BB_RS04050	COG0387	Pfam Sodium calcium exchanger
BB_RS04060	COG3468	outer membrane autotransporter barrel domain protein
BB_RS04065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB_RS04115	COG4772	TonB-dependent receptor
BB_RS04125	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB_RS04150	COG1054	Belongs to the UPF0176 family
BB_RS04155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB_RS04155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB_RS04165	COG0489	protein tyrosine kinase activity
BB_RS04210	COG2081	HI0933 family
BB_RS04215	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB_RS04225	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BB_RS04230	COG0509	glycine decarboxylation via glycine cleavage system
BB_RS04235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB_RS04235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BB_RS04255	COG1024	Enoyl-CoA hydratase
BB_RS04275	COG4172	Belongs to the ABC transporter superfamily
BB_RS04280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS04285	COG0601	transmembrane transport
BB_RS04290	COG0747	negative chemotaxis
BB_RS04300	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB_RS04305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS04330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB_RS04335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BB_RS04350	COG0438	transferase activity, transferring glycosyl groups
BB_RS04365	COG0438	transferase activity, transferring glycosyl groups
BB_RS04370	COG0438	transferase activity, transferring glycosyl groups
BB_RS04375	COG0166	Belongs to the GPI family
BB_RS04390	COG0277	FAD linked oxidase domain protein
BB_RS04395	COG0745	RESPONSE REGULATOR receiver
BB_RS04400	COG0642	Histidine kinase
BB_RS04405	COG1368	sulfuric ester hydrolase activity
BB_RS04440	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BB_RS04450	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BB_RS04455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BB_RS04485	COG0012	GTP binding
BB_RS04490	COG0582	viral genome integration into host DNA
BB_RS04510	COG0464	growth
BB_RS04515	COG1404	Belongs to the peptidase S8 family
BB_RS04550	COG0745	RESPONSE REGULATOR receiver
BB_RS04555	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS04560	COG1309	transcriptional regulator
BB_RS04570	COG2814	Major facilitator Superfamily
BB_RS04595	COG0281	malic enzyme
BB_RS04595	COG0280	phosphate acetyltransferase
BB_RS04605	COG0601	transmembrane transport
BB_RS04610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS04615	COG4172	Belongs to the ABC transporter superfamily
BB_RS04620	COG0747	negative chemotaxis
BB_RS04630	COG0583	DNA-binding transcription factor activity
BB_RS04645	COG0640	Transcriptional regulator
BB_RS04660	COG3135	benzoate transporter
BB_RS04665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BB_RS04670	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BB_RS04675	COG0742	ribosomal rna small subunit methyltransferase
BB_RS04690	COG3639	organic phosphonate transmembrane transporter activity
BB_RS04695	COG3639	organic phosphonate transmembrane transporter activity
BB_RS04700	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BB_RS04725	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BB_RS04730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB_RS04740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BB_RS04745	COG1058	Belongs to the CinA family
BB_RS04745	COG1546	Belongs to the CinA family
BB_RS04750	COG0284	orotidine-5'-phosphate decarboxylase activity
BB_RS04755	COG1252	NADH dehydrogenase
BB_RS04780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BB_RS04800	COG1053	succinate dehydrogenase
BB_RS04810	COG0583	DNA-binding transcription factor activity
BB_RS04815	COG1053	succinate dehydrogenase
BB_RS04820	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS04825	COG1414	Transcriptional regulator
BB_RS04840	COG1335	isochorismatase
BB_RS04855	COG0405	Gamma-glutamyltransferase
BB_RS04870	COG1960	acyl-CoA dehydrogenase activity
BB_RS04875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS04880	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS04885	COG0583	DNA-binding transcription factor activity
BB_RS04910	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS04915	COG0583	DNA-binding transcription factor activity
BB_RS04920	COG2199	diguanylate cyclase activity
BB_RS04945	COG3842	ATPase activity
BB_RS04970	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS04970	COG1024	Enoyl-CoA hydratase
BB_RS04975	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS04990	COG4172	Belongs to the ABC transporter superfamily
BB_RS05000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS05025	COG2423	ornithine cyclodeaminase activity
BB_RS05035	COG0473	3-isopropylmalate dehydrogenase activity
BB_RS05040	COG0066	3-isopropylmalate dehydratase activity
BB_RS05045	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB_RS05055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS05065	COG0583	DNA-binding transcription factor activity
BB_RS05080	COG0583	DNA-binding transcription factor activity
BB_RS05085	COG3119	arylsulfatase activity
BB_RS05095	COG0583	DNA-binding transcription factor activity
BB_RS05105	COG1024	Enoyl-CoA hydratase
BB_RS05115	COG2084	Dehydrogenase
BB_RS05135	COG1850	ribulose-bisphosphate carboxylase activity
BB_RS05145	COG0583	DNA-binding transcription factor activity
BB_RS05150	COG1024	Enoyl-CoA hydratase
BB_RS05175	COG3842	ATPase activity
BB_RS05180	COG1177	transmembrane transport
BB_RS05195	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05200	COG3386	PFAM SMP-30 Gluconolaconase
BB_RS05210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB_RS05230	COG0583	DNA-binding transcription factor activity
BB_RS05240	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS05255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS05295	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS05330	COG1802	Transcriptional regulator
BB_RS05335	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS05360	COG1335	isochorismatase
BB_RS05365	COG0583	DNA-binding transcription factor activity
BB_RS05380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05395	COG0183	Belongs to the thiolase family
BB_RS05400	COG1024	Enoyl-CoA hydratase
BB_RS05410	COG1024	Enoyl-CoA hydratase
BB_RS05415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05420	COG0583	DNA-binding transcription factor activity
BB_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05445	COG0583	DNA-binding transcription factor activity
BB_RS05450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05455	COG1960	acyl-CoA dehydrogenase activity
BB_RS05460	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05465	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB_RS05470	COG4191	Histidine kinase
BB_RS05475	COG4566	intracellular signal transduction
BB_RS05505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS05515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB_RS05560	COG0583	DNA-binding transcription factor activity
BB_RS05580	COG1024	Enoyl-CoA hydratase
BB_RS05585	COG1024	Enoyl-CoA hydratase
BB_RS05590	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS05595	COG1960	acyl-CoA dehydrogenase activity
BB_RS05635	COG3685	Protein conserved in bacteria
BB_RS05645	COG0387	Pfam Sodium calcium exchanger
BB_RS05650	COG3795	YCII-related domain
BB_RS05655	COG2188	Transcriptional regulator
BB_RS05675	COG0154	amidase activity
BB_RS05680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05685	COG1024	Enoyl-CoA hydratase
BB_RS05695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS05715	COG1414	Transcriptional regulator
BB_RS05730	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB_RS05735	COG0251	oxidation-reduction process
BB_RS05740	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS05760	COG1902	pentaerythritol trinitrate reductase activity
BB_RS05765	COG0583	DNA-binding transcription factor activity
BB_RS05775	COG0590	tRNA wobble adenosine to inosine editing
BB_RS05780	COG2807	transmembrane transport
BB_RS05790	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05795	COG0154	amidase activity
BB_RS05800	COG0307	riboflavin synthase, alpha
BB_RS05805	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS05810	COG1522	sequence-specific DNA binding
BB_RS05820	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS05830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS05840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB_RS05850	COG1063	alcohol dehydrogenase
BB_RS05870	COG1418	mRNA catabolic process
BB_RS05875	COG1448	Aminotransferase
BB_RS05880	COG1335	isochorismatase
BB_RS05905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS05910	COG2274	protein secretion by the type I secretion system
BB_RS05920	COG1538	Outer membrane efflux protein
BB_RS05935	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BB_RS05945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS05955	COG1309	transcriptional regulator
BB_RS05960	COG1960	acyl-CoA dehydrogenase activity
BB_RS05965	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS05970	COG2076	Multidrug Resistance protein
BB_RS05975	COG1309	transcriptional regulator
BB_RS05985	COG0583	DNA-binding transcription factor activity
BB_RS05995	COG0840	transmembrane signaling receptor activity
BB_RS06010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS06035	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS06045	COG1024	Enoyl-CoA hydratase
BB_RS06055	COG2199	diguanylate cyclase activity
BB_RS06055	COG2203	Gaf domain
BB_RS06070	COG0456	acetyltransferase
BB_RS06080	COG0154	amidase activity
BB_RS06085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS06085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS06095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS06110	COG3945	hemerythrin HHE cation binding domain
BB_RS06125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB_RS06125	COG2169	Transcriptional regulator
BB_RS06145	COG1271	oxidase subunit
BB_RS06150	COG1294	oxidase, subunit
BB_RS06155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS06185	COG0596	Alpha beta hydrolase
BB_RS06190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB_RS06230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BB_RS06235	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BB_RS06245	COG2070	2-Nitropropane dioxygenase
BB_RS06260	COG1917	Cupin 2, conserved barrel domain protein
BB_RS06260	COG2207	Transcriptional regulator
BB_RS06280	COG2900	Belongs to the SlyX family
BB_RS06285	COG1671	Belongs to the UPF0178 family
BB_RS06290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB_RS06320	COG0583	DNA-binding transcription factor activity
BB_RS06325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS06335	COG0583	DNA-binding transcription factor activity
BB_RS06360	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BB_RS06370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB_RS06375	COG1845	cytochrome c oxidase, subunit III
BB_RS06380	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BB_RS06385	COG0640	Transcriptional regulator
BB_RS06405	COG3220	belongs to the UPF0276 family
BB_RS06435	COG4942	peptidase
BB_RS06450	COG1666	GTP binding
BB_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS06485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BB_RS06490	COG1845	cytochrome c oxidase, subunit III
BB_RS06495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB_RS06500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BB_RS06505	COG0477	Major facilitator Superfamily
BB_RS06520	COG5006	permease, DMT superfamily
BB_RS06540	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BB_RS06550	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BB_RS06555	COG3383	formate dehydrogenase (NAD+) activity
BB_RS06575	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BB_RS06580	COG0303	'Molybdopterin
BB_RS06585	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB_RS06595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BB_RS06600	COG0315	cyclic pyranopterin monophosphate synthase activity
BB_RS06610	COG0412	Dienelactone hydrolase
BB_RS06620	COG0678	peroxiredoxin activity
BB_RS06630	COG0697	spore germination
BB_RS06675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BB_RS06680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB_RS06685	COG1335	isochorismatase
BB_RS06690	COG0523	cobalamin synthesis protein
BB_RS06710	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS06720	COG1802	Transcriptional regulator
BB_RS06740	COG0667	Aldo Keto reductase
BB_RS06745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BB_RS06750	COG4535	Mg2 and Co2 transporter CorC
BB_RS06755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BB_RS06760	COG1702	phosphate starvation-inducible protein PhoH
BB_RS06765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BB_RS06775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB_RS06780	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BB_RS06785	COG1862	Preprotein translocase
BB_RS06790	COG0343	queuine tRNA-ribosyltransferase activity
BB_RS06795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BB_RS06800	COG2027	D-alanyl-D-alanine carboxypeptidase
BB_RS06810	COG3468	outer membrane autotransporter barrel domain protein
BB_RS06840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BB_RS06845	COG0741	lytic transglycosylase activity
BB_RS06850	COG0436	Aminotransferase
BB_RS06860	COG0281	malic enzyme
BB_RS06860	COG0280	phosphate acetyltransferase
BB_RS06870	COG2732	(Barnase) inhibitor
BB_RS06875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB_RS06880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BB_RS06885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BB_RS06890	COG0126	phosphoglycerate kinase activity
BB_RS06895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BB_RS06900	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB_RS06915	COG0625	glutathione transferase activity
BB_RS06945	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BB_RS06955	COG0306	phosphate transporter
BB_RS06960	COG0521	Mo-molybdopterin cofactor biosynthetic process
BB_RS06970	COG0739	heme binding
BB_RS06980	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BB_RS07030	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BB_RS07040	COG2944	sequence-specific DNA binding
BB_RS07045	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BB_RS07050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB_RS07055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BB_RS07060	COG0009	L-threonylcarbamoyladenylate synthase
BB_RS07065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS07070	COG1414	Transcriptional regulator
BB_RS07085	COG0765	amino acid transport
BB_RS07090	COG1126	abc transporter atp-binding protein
BB_RS07095	COG0028	Belongs to the TPP enzyme family
BB_RS07110	COG0028	Belongs to the TPP enzyme family
BB_RS07115	COG0583	DNA-binding transcription factor activity
BB_RS07120	COG4974	Belongs to the 'phage' integrase family
BB_RS07125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB_RS07130	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BB_RS07140	COG1686	Belongs to the peptidase S11 family
BB_RS07150	COG2814	Major facilitator Superfamily
BB_RS07160	COG1074	ATP-dependent DNA helicase activity
BB_RS07165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB_RS07180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS07185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB_RS07195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS07205	COG0505	Belongs to the CarA family
BB_RS07210	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BB_RS07215	COG4221	oxidoreductase activity
BB_RS07220	COG0406	alpha-ribazole phosphatase activity
BB_RS07230	COG3842	ATPase activity
BB_RS07250	COG2233	PERMEase
BB_RS07255	COG0840	transmembrane signaling receptor activity
BB_RS07260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB_RS07265	COG1534	Rna-binding protein
BB_RS07275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB_RS07295	COG0248	Ppx GppA phosphatase
BB_RS07335	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS07345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS07350	COG3620	sequence-specific DNA binding
BB_RS07410	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS07440	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS07475	COG2072	flavoprotein involved in K transport
BB_RS07480	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS07510	COG1137	ATPase activity
BB_RS07520	COG0154	amidase activity
BB_RS07525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS07540	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS07545	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS07550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS07555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS07560	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS07570	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB_RS07580	COG1522	sequence-specific DNA binding
BB_RS07585	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB_RS07590	COG1473	amidohydrolase
BB_RS07595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS07600	COG4597	amino acid ABC transporter
BB_RS07605	COG0765	amino acid transport
BB_RS07610	COG1126	abc transporter atp-binding protein
BB_RS07625	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB_RS07655	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS07670	COG2985	domain, Protein
BB_RS07675	COG0583	DNA-binding transcription factor activity
BB_RS07710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB_RS07750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB_RS07760	COG1132	(ABC) transporter
BB_RS07780	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BB_RS07790	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS07800	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BB_RS07810	COG0511	ligase activity, forming carbon-carbon bonds
BB_RS07835	COG2188	Transcriptional regulator
BB_RS07840	COG0439	Biotin carboxylase
BB_RS07850	COG0511	ligase activity, forming carbon-carbon bonds
BB_RS07865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS07895	COG3971	2-oxopent-4-enoate hydratase activity
BB_RS07900	COG0583	DNA-binding transcription factor activity
BB_RS07915	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB_RS07955	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BB_RS07965	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS08005	COG0251	oxidation-reduction process
BB_RS08010	COG1902	pentaerythritol trinitrate reductase activity
BB_RS08040	COG4789	Type iii secretion
BB_RS08105	COG4669	(LipO)protein
BB_RS08140	COG4790	Type iii secretion
BB_RS08145	COG4794	Type iii secretion
BB_RS08150	COG4791	protein targeting
BB_RS08155	COG4792	protein secretion
BB_RS08170	COG1595	DNA-templated transcription, initiation
BB_RS08190	COG2208	phosphoserine phosphatase activity
BB_RS08190	COG2770	Histidine kinase
BB_RS08200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB_RS08205	COG2172	sigma factor antagonist activity
BB_RS08210	COG1366	Belongs to the anti-sigma-factor antagonist family
BB_RS08215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB_RS08250	COG2321	neutral zinc metallopeptidase
BB_RS08255	COG0009	L-threonylcarbamoyladenylate synthase
BB_RS08260	COG1994	Peptidase M50
BB_RS08265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS08270	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BB_RS08275	COG3539	Fimbrial protein
BB_RS08285	COG2850	peptidyl-arginine hydroxylation
BB_RS08290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BB_RS08355	COG1475	DNA binding
BB_RS08455	COG4695	Portal protein
BB_RS08460	COG0740	serine-type endopeptidase activity
BB_RS08570	COG3360	Dodecin
BB_RS08605	COG0668	transmembrane transport
BB_RS08625	COG0483	inositol monophosphate 1-phosphatase activity
BB_RS08630	COG1253	flavin adenine dinucleotide binding
BB_RS08650	COG3063	Type IV pilus biogenesis stability protein PilW
BB_RS08665	COG0825	malonyl-CoA metabolic process
BB_RS08670	COG0037	tRNA processing
BB_RS08675	COG0527	aspartate kinase activity
BB_RS08700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS08700	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS08715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB_RS08720	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS08735	COG0583	DNA-binding transcription factor activity
BB_RS08760	COG3842	ATPase activity
BB_RS08770	COG1902	pentaerythritol trinitrate reductase activity
BB_RS08770	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB_RS08775	COG1414	Transcriptional regulator
BB_RS08780	COG1832	CoA-binding protein
BB_RS08790	COG0251	oxidation-reduction process
BB_RS08815	COG1902	pentaerythritol trinitrate reductase activity
BB_RS08825	COG1215	transferase activity, transferring glycosyl groups
BB_RS08830	COG0726	polysaccharide deacetylase
BB_RS08830	COG1649	PFAM Uncharacterised BCR, COG1649
BB_RS08850	COG1846	Transcriptional regulator
BB_RS08875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB_RS08875	COG2010	Cytochrome c
BB_RS08880	COG2080	2 iron, 2 sulfur cluster binding
BB_RS08885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB_RS08890	COG3473	Maleate cis-trans isomerase
BB_RS08895	COG0596	Alpha beta hydrolase
BB_RS08900	COG2309	aminopeptidase activity
BB_RS08905	COG1335	isochorismatase
BB_RS08910	COG2010	Cytochrome c
BB_RS08910	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB_RS08915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB_RS08915	COG1017	nitric oxide dioxygenase activity
BB_RS08930	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS08940	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS08950	COG0183	Belongs to the thiolase family
BB_RS08955	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS08955	COG1024	Enoyl-CoA hydratase
BB_RS08970	COG0183	Belongs to the thiolase family
BB_RS08985	COG2197	response regulator
BB_RS09000	COG0166	Belongs to the GPI family
BB_RS09005	COG1045	serine acetyltransferase
BB_RS09015	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB_RS09020	COG0483	inositol monophosphate 1-phosphatase activity
BB_RS09030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB_RS09045	COG0210	DNA helicase
BB_RS09050	COG0598	Magnesium transport protein CorA
BB_RS09060	COG0747	negative chemotaxis
BB_RS09065	COG0601	transmembrane transport
BB_RS09070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS09075	COG4172	Belongs to the ABC transporter superfamily
BB_RS09080	COG1846	Transcriptional regulator
BB_RS09125	COG4964	Belongs to the GSP D family
BB_RS09190	COG3474	cytochrome
BB_RS09195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BB_RS09210	COG3384	dioxygenase
BB_RS09215	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BB_RS09235	COG2885	chlorophyll binding
BB_RS09270	COG0697	spore germination
BB_RS09275	COG0730	response to heat
BB_RS09290	COG1511	domain protein
BB_RS09290	COG3264	Mechanosensitive ion channel
BB_RS09295	COG0583	DNA-binding transcription factor activity
BB_RS09300	COG0427	acetyl-CoA hydrolase
BB_RS09305	COG0385	Bile acid
BB_RS09345	COG3468	outer membrane autotransporter barrel domain protein
BB_RS09355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BB_RS09360	COG0799	negative regulation of ribosome biogenesis
BB_RS09365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB_RS09375	COG0151	Belongs to the GarS family
BB_RS09385	COG0433	COG0433 Predicted ATPase
BB_RS09390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB_RS09400	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS09425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BB_RS09435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS09445	COG0747	negative chemotaxis
BB_RS09455	COG0473	3-isopropylmalate dehydrogenase activity
BB_RS09460	COG2814	Major facilitator Superfamily
BB_RS09465	COG1566	PFAM secretion protein HlyD family protein
BB_RS09475	COG1846	Transcriptional regulator
BB_RS09485	COG0697	spore germination
BB_RS09495	COG0501	Belongs to the peptidase M48B family
BB_RS09515	COG0583	DNA-binding transcription factor activity
BB_RS09520	COG3842	ATPase activity
BB_RS09525	COG1178	ABC-type Fe3 transport system permease component
BB_RS09530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB_RS09535	COG1840	ABC-type Fe3 transport system, periplasmic component
BB_RS09570	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS09580	COG1722	exodeoxyribonuclease VII activity
BB_RS09585	COG0142	geranyltranstransferase activity
BB_RS09595	COG1469	GTP cyclohydrolase I activity
BB_RS09600	COG0360	Binds together with S18 to 16S ribosomal RNA
BB_RS09605	COG2965	DNA replication, synthesis of RNA primer
BB_RS09610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BB_RS09625	COG0305	Participates in initiation and elongation during chromosome replication
BB_RS09635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BB_RS09640	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BB_RS09645	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BB_RS09650	COG3737	Protein of unknown function (DUF498/DUF598)
BB_RS09655	COG0436	Aminotransferase
BB_RS09675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BB_RS09680	COG0308	aminopeptidase N
BB_RS09700	COG0312	modulator of DNA gyrase
BB_RS09705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB_RS09710	COG3210	domain, Protein
BB_RS09710	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB_RS09710	COG3064	Membrane
BB_RS09710	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB_RS09710	COG3064	Membrane
BB_RS09710	COG3210	domain, Protein
BB_RS09715	COG0277	FAD linked oxidase domain protein
BB_RS09720	COG0277	FAD linked oxidase domain protein
BB_RS09725	COG0277	FAD linked oxidase domain protein
BB_RS09730	COG0247	lactate metabolic process
BB_RS09735	COG2819	hydrolase of the alpha beta superfamily
BB_RS09775	COG0583	DNA-binding transcription factor activity
BB_RS09780	COG0482	sulfurtransferase activity
BB_RS09785	COG0730	response to heat
BB_RS09790	COG0625	glutathione transferase activity
BB_RS09795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB_RS09800	COG3909	cytochrome
BB_RS09830	COG3706	GGDEF domain
BB_RS09865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BB_RS09870	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BB_RS09880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB_RS09885	COG0069	glutamate synthase activity
BB_RS09890	COG2391	methyltransferase activity
BB_RS09895	COG0679	Auxin Efflux Carrier
BB_RS09920	COG0557	exoribonuclease II activity
BB_RS09925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB_RS09935	COG3128	pkhd-type hydroxylase
BB_RS09940	COG0776	regulation of translation
BB_RS09970	COG0642	Histidine kinase
BB_RS09975	COG3158	transport of potassium into the cell
BB_RS09985	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BB_RS09990	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB_RS10000	COG0583	DNA-binding transcription factor activity
BB_RS10010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB_RS10030	COG2186	Transcriptional regulator
BB_RS10035	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB_RS10055	COG0268	Binds directly to 16S ribosomal RNA
BB_RS10065	COG0728	peptidoglycan biosynthetic process
BB_RS10075	COG0563	adenylate kinase activity
BB_RS10080	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BB_RS10085	COG2835	tetraacyldisaccharide 4'-kinase activity
BB_RS10095	COG0848	biopolymer transport protein
BB_RS10100	COG0811	peptide transport
BB_RS10110	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BB_RS10120	COG0183	Belongs to the thiolase family
BB_RS10130	COG1278	Cold shock
BB_RS10145	COG4953	penicillin-binding protein 1C
BB_RS10150	COG0542	response to heat
BB_RS10155	COG2995	paraquat-inducible protein a
BB_RS10160	COG3008	intermembrane lipid transfer
BB_RS10160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB_RS10170	COG0506	proline dehydrogenase activity
BB_RS10170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB_RS10170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BB_RS10200	COG2271	Major facilitator Superfamily
BB_RS10205	COG1309	transcriptional regulator
BB_RS10210	COG3468	outer membrane autotransporter barrel domain protein
BB_RS10215	COG0004	ammonium transporteR
BB_RS10235	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BB_RS10240	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BB_RS10245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BB_RS10250	COG0072	phenylalanine-tRNA ligase activity
BB_RS10250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB_RS10285	COG0500	methyltransferase
BB_RS10300	COG2367	Beta-lactamase
BB_RS10310	COG1522	sequence-specific DNA binding
BB_RS10325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS10365	COG0540	Belongs to the ATCase OTCase family
BB_RS10370	COG2974	May be involved in recombination
BB_RS10380	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS10385	COG0583	DNA-binding transcription factor activity
BB_RS10390	COG0183	Belongs to the thiolase family
BB_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS10420	COG3842	ATPase activity
BB_RS10425	COG1024	Enoyl-CoA hydratase
BB_RS10425	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS10445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BB_RS10450	COG2137	regulation of response to DNA damage stimulus
BB_RS10470	COG0045	succinate-CoA ligase (ADP-forming) activity
BB_RS10475	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BB_RS10480	COG0861	Integral membrane protein TerC family
BB_RS10485	COG0861	Integral membrane protein TerC family
BB_RS10555	COG4964	Belongs to the GSP D family
BB_RS10585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BB_RS10595	COG1295	ribonuclease BN
BB_RS10610	COG0745	RESPONSE REGULATOR receiver
BB_RS10615	COG2205	protein histidine kinase activity
BB_RS10620	COG3300	MHYT domain
BB_RS10620	COG5001	Diguanylate cyclase
BB_RS10625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BB_RS10635	COG1763	Mo-molybdopterin cofactor biosynthetic process
BB_RS10640	COG0303	'Molybdopterin
BB_RS10645	COG0746	molybdenum cofactor guanylyltransferase activity
BB_RS10650	COG0489	protein tyrosine kinase activity
BB_RS10680	COG0243	molybdopterin cofactor binding
BB_RS10680	COG3383	formate dehydrogenase (NAD+) activity
BB_RS10685	COG0437	4 iron, 4 sulfur cluster binding
BB_RS10715	COG1122	ATPase activity
BB_RS10740	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BB_RS10755	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS10770	COG0135	phosphoribosylanthranilate isomerase activity
BB_RS10810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB_RS10820	COG2197	response regulator
BB_RS10825	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BB_RS10830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB_RS10845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB_RS10850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB_RS10860	COG1764	response to oxidative stress
BB_RS10865	COG2423	ornithine cyclodeaminase activity
BB_RS10875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS10880	COG0765	amino acid transport
BB_RS10885	COG0765	amino acid transport
BB_RS10890	COG1126	abc transporter atp-binding protein
BB_RS10905	COG0586	Pfam SNARE associated Golgi protein
BB_RS10915	COG1522	sequence-specific DNA binding
BB_RS10925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BB_RS10930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BB_RS10935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BB_RS10940	COG0196	riboflavin kinase activity
BB_RS10945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BB_RS10950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BB_RS10950	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BB_RS10965	COG0210	DNA helicase
BB_RS10970	COG4771	TonB-dependent receptor
BB_RS10975	COG0488	(ABC) transporter
BB_RS10980	COG2890	protein-(glutamine-N5) methyltransferase activity
BB_RS10985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB_RS10990	COG2171	N-acyltransferase activity
BB_RS10995	COG0436	Aminotransferase
BB_RS11005	COG0582	viral genome integration into host DNA
BB_RS11035	COG3723	Recombinational DNA repair protein, rece pathway
BB_RS11220	COG1196	nuclear chromosome segregation
BB_RS11285	COG2135	peptidase activity
BB_RS11310	COG1278	Cold shock
BB_RS11320	COG1278	Cold shock
BB_RS11330	COG0544	peptidyl-prolyl cis-trans isomerase activity
BB_RS11335	COG0740	serine-type endopeptidase activity
BB_RS11345	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BB_RS11350	COG0583	DNA-binding transcription factor activity
BB_RS11355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS11370	COG1024	Enoyl-CoA hydratase
BB_RS11380	COG0183	Belongs to the thiolase family
BB_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS11390	COG1960	acyl-CoA dehydrogenase activity
BB_RS11405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BB_RS11420	COG3468	outer membrane autotransporter barrel domain protein
BB_RS11425	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BB_RS11435	COG0556	nucleotide-excision repair
BB_RS11440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB_RS11450	COG1104	cysteine desulfurase activity
BB_RS11455	COG0822	iron-sulfur transferase activity
BB_RS11460	COG0316	Belongs to the HesB IscA family
BB_RS11465	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BB_RS11470	COG0443	Heat shock 70 kDa protein
BB_RS11475	COG0633	Ferredoxin
BB_RS11490	COG1024	Enoyl-CoA hydratase
BB_RS11520	COG1022	Amp-dependent synthetase and ligase
BB_RS11535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BB_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS11545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB_RS11550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BB_RS11565	COG1136	(ABC) transporter
BB_RS11570	COG0084	hydrolase, TatD family'
BB_RS11590	COG0658	competence protein
BB_RS11590	COG2333	competence protein COMEC
BB_RS11600	COG0613	PHP domain protein
BB_RS11610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS11615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS11615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS11620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS11625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB_RS11625	COG0047	phosphoribosylformylglycinamidine synthase activity
BB_RS11630	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB_RS11630	COG3064	Membrane
BB_RS11630	COG3210	domain, Protein
BB_RS11650	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS11665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB_RS11680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB_RS11685	COG2197	response regulator
BB_RS11705	COG0519	Catalyzes the synthesis of GMP from XMP
BB_RS11705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB_RS11715	COG0477	Major facilitator Superfamily
BB_RS11720	COG2814	Major facilitator Superfamily
BB_RS11760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BB_RS11775	COG3618	amidohydrolase
BB_RS11785	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS11810	COG2079	MmgE PrpD family protein
BB_RS11815	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS11850	COG1280	lysine exporter protein (LysE YggA)
BB_RS11865	COG0747	negative chemotaxis
BB_RS11870	COG0601	transmembrane transport
BB_RS11875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS11880	COG4172	Belongs to the ABC transporter superfamily
BB_RS11885	COG1609	Transcriptional regulator
BB_RS11900	COG0789	Transcriptional regulator
BB_RS11925	COG2188	Transcriptional regulator
BB_RS11930	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS11950	COG1802	Transcriptional regulator
BB_RS11965	COG0842	Transport permease protein
BB_RS11970	COG0842	Transport permease protein
BB_RS11975	COG1131	(ABC) transporter
BB_RS11995	COG0656	L-ascorbic acid biosynthetic process
BB_RS12000	COG3284	Transcriptional regulator
BB_RS12005	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS12020	COG2733	membrane
BB_RS12025	COG0583	DNA-binding transcription factor activity
BB_RS12030	COG0384	phenazine biosynthesis protein PhzF
BB_RS12035	COG5507	3-demethylubiquinone-9 3-methyltransferase
BB_RS12040	COG2169	Transcriptional regulator
BB_RS12070	COG0659	secondary active sulfate transmembrane transporter activity
BB_RS12095	COG1132	(ABC) transporter
BB_RS12135	COG2207	Transcriptional regulator
BB_RS12170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB_RS12175	COG1280	lysine exporter protein (LysE YggA)
BB_RS12195	COG0625	glutathione transferase activity
BB_RS12210	COG0697	spore germination
BB_RS12225	COG0534	Mate efflux family protein
BB_RS12230	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BB_RS12245	COG3246	L-lysine catabolic process to acetate
BB_RS12250	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS12255	COG0583	DNA-binding transcription factor activity
BB_RS12270	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS12275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB_RS12280	COG3622	Belongs to the hyi family
BB_RS12290	COG0129	dihydroxy-acid dehydratase activity
BB_RS12320	COG0129	dihydroxy-acid dehydratase activity
BB_RS12325	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS12335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BB_RS12350	COG2188	Transcriptional regulator
BB_RS12360	COG0583	DNA-binding transcription factor activity
BB_RS12370	COG0501	Belongs to the peptidase M48B family
BB_RS12380	COG2814	Major facilitator Superfamily
BB_RS12385	COG0583	DNA-binding transcription factor activity
BB_RS12450	COG2837	iron assimilation
BB_RS12470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS12475	COG1335	isochorismatase
BB_RS12515	COG2801	Transposase and inactivated derivatives
BB_RS12525	COG2963	transposase activity
BB_RS12555	COG2346	COG2346, Truncated hemoglobins
BB_RS12565	COG1126	abc transporter atp-binding protein
BB_RS12570	COG0765	amino acid transport
BB_RS12575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS12585	COG0789	Transcriptional regulator
BB_RS12595	COG0165	Argininosuccinate lyase
BB_RS12600	COG0668	transmembrane transport
BB_RS12645	COG0747	negative chemotaxis
BB_RS12650	COG0601	transmembrane transport
BB_RS12655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS12660	COG4172	Belongs to the ABC transporter superfamily
BB_RS12665	COG1280	lysine exporter protein (LysE YggA)
BB_RS12675	COG2814	Major facilitator Superfamily
BB_RS12680	COG3161	chorismate lyase activity
BB_RS12685	COG1187	pseudouridine synthase activity
BB_RS12695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS12715	COG1999	signal sequence binding
BB_RS12720	COG0339	signal peptide processing
BB_RS12725	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BB_RS12730	COG4566	intracellular signal transduction
BB_RS12740	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BB_RS12745	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB_RS12750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB_RS12755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BB_RS12785	COG0745	RESPONSE REGULATOR receiver
BB_RS12790	COG2198	Histidine kinase
BB_RS12790	COG0643	Histidine kinase
BB_RS12800	COG0840	transmembrane signaling receptor activity
BB_RS12805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BB_RS12810	COG2201	protein-glutamate methylesterase activity
BB_RS12815	COG0745	RESPONSE REGULATOR receiver
BB_RS12820	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BB_RS12855	COG1815	bacterial-type flagellum-dependent cell motility
BB_RS12860	COG1558	bacterial-type flagellum-dependent cell motility
BB_RS12870	COG1749	Flagellar hook protein flgE
BB_RS12885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BB_RS12900	COG1256	bacterial-type flagellum assembly
BB_RS12910	COG0840	transmembrane signaling receptor activity
BB_RS12925	COG0840	transmembrane signaling receptor activity
BB_RS12930	COG0840	transmembrane signaling receptor activity
BB_RS12945	COG1338	Plays a role in the flagellum-specific transport system
BB_RS12955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB_RS12965	COG1580	Controls the rotational direction of flagella during chemotaxis
BB_RS12980	COG1157	protein secretion by the type III secretion system
BB_RS12990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BB_RS13000	COG1677	Flagellar hook-basal body complex protein FliE
BB_RS13010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BB_RS13040	COG0285	dihydrofolate synthase activity
BB_RS13070	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB_RS13075	COG0024	Methionine aminopeptidase
BB_RS13080	COG0052	Belongs to the universal ribosomal protein uS2 family
BB_RS13085	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BB_RS13090	COG0528	UMP kinase activity
BB_RS13095	COG0233	cytoplasmic translational termination
BB_RS13100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BB_RS13110	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BB_RS13115	COG0750	zinc metalloprotease
BB_RS13120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB_RS13125	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BB_RS13130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BB_RS13135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BB_RS13150	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB_RS13155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB_RS13170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BB_RS13170	COG0519	Catalyzes the synthesis of GMP from XMP
BB_RS13180	COG0330	HflC and HflK could
BB_RS13185	COG3706	GGDEF domain
BB_RS13190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BB_RS13195	COG2867	negative regulation of translational initiation
BB_RS13205	COG1960	acyl-CoA dehydrogenase activity
BB_RS13210	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BB_RS13235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BB_RS13240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BB_RS13245	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB_RS13250	COG0084	hydrolase, TatD family'
BB_RS13270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS13275	COG0765	amino acid transport
BB_RS13280	COG1126	abc transporter atp-binding protein
BB_RS13285	COG0010	Belongs to the arginase family
BB_RS13290	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB_RS13295	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS13305	COG0028	Belongs to the TPP enzyme family
BB_RS13315	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS13315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS13325	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS13335	COG3189	MarR family transcriptional regulator
BB_RS13345	COG2985	domain, Protein
BB_RS13350	COG0076	glutamate decarboxylase activity
BB_RS13365	COG1595	DNA-templated transcription, initiation
BB_RS13375	COG0861	Integral membrane protein TerC family
BB_RS13400	COG2988	succinylglutamate desuccinylase activity
BB_RS13415	COG1253	flavin adenine dinucleotide binding
BB_RS13425	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS13430	COG2084	Dehydrogenase
BB_RS13445	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB_RS13460	COG2814	Major facilitator Superfamily
BB_RS13470	COG0583	DNA-binding transcription factor activity
BB_RS13480	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS13495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS13500	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BB_RS13505	COG0439	Biotin carboxylase
BB_RS13525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS13540	COG0395	ABC-type sugar transport system, permease component
BB_RS13545	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB_RS13555	COG3842	ATPase activity
BB_RS13560	COG1414	Transcriptional regulator
BB_RS13565	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS13575	COG2188	Transcriptional regulator
BB_RS13600	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS13605	COG0583	DNA-binding transcription factor activity
BB_RS13625	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB_RS13635	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB_RS13645	COG1228	amidohydrolase
BB_RS13675	COG0861	Integral membrane protein TerC family
BB_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS13695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BB_RS13700	COG0714	Associated with various cellular activities
BB_RS13735	COG3119	arylsulfatase activity
BB_RS13755	COG2197	response regulator
BB_RS13765	COG2944	sequence-specific DNA binding
BB_RS13770	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
BB_RS13775	COG0625	glutathione transferase activity
BB_RS13790	COG3119	arylsulfatase activity
BB_RS13800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB_RS13805	COG1902	pentaerythritol trinitrate reductase activity
BB_RS13815	COG0583	DNA-binding transcription factor activity
BB_RS13855	COG1309	transcriptional regulator
BB_RS13860	COG1414	Transcriptional regulator
BB_RS13865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS13870	COG0183	Belongs to the thiolase family
BB_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS13890	COG0583	DNA-binding transcription factor activity
BB_RS13895	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS13900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS13905	COG1024	Enoyl-CoA hydratase
BB_RS13915	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS13920	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS13920	COG1024	Enoyl-CoA hydratase
BB_RS13925	COG0183	Belongs to the thiolase family
BB_RS13930	COG1454	alcohol dehydrogenase
BB_RS13935	COG0824	Thioesterase
BB_RS13955	COG0583	DNA-binding transcription factor activity
BB_RS13960	COG0431	NADPH-dependent FMN reductase
BB_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS13995	COG0583	DNA-binding transcription factor activity
BB_RS14005	COG3706	GGDEF domain
BB_RS14005	COG4251	negative regulation of phosphorylation
BB_RS14005	COG5001	Diguanylate cyclase
BB_RS14005	COG2203	Gaf domain
BB_RS14010	COG1454	alcohol dehydrogenase
BB_RS14010	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS14020	COG0330	HflC and HflK could
BB_RS14030	COG1126	abc transporter atp-binding protein
BB_RS14035	COG0765	amino acid transport
BB_RS14040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS14055	COG0243	molybdopterin cofactor binding
BB_RS14060	COG3043	anaerobic respiration
BB_RS14065	COG3005	denitrification pathway
BB_RS14070	COG4133	protoheme IX ABC transporter activity
BB_RS14090	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BB_RS14100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB_RS14130	COG4948	Mandelate Racemase Muconate Lactonizing
BB_RS14135	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS14140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB_RS14145	COG0066	3-isopropylmalate dehydratase activity
BB_RS14160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS14170	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS14180	COG1802	Transcriptional regulator
BB_RS14195	COG0583	DNA-binding transcription factor activity
BB_RS14205	COG3468	outer membrane autotransporter barrel domain protein
BB_RS14215	COG1695	Transcriptional regulator
BB_RS14225	COG3568	Endonuclease Exonuclease Phosphatase
BB_RS14230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BB_RS14235	COG0392	lysyltransferase activity
BB_RS14270	COG4575	ribosome binding
BB_RS14275	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BB_RS14285	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS14335	COG0028	Belongs to the TPP enzyme family
BB_RS14345	COG2204	response regulator
BB_RS14350	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BB_RS14360	COG0297	glycogen (starch) synthase activity
BB_RS14365	COG0366	Alpha amylase catalytic
BB_RS14375	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BB_RS14390	COG1640	4-alpha-glucanotransferase
BB_RS14435	COG0667	Aldo Keto reductase
BB_RS14450	COG2259	Doxx family
BB_RS14470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS14490	COG0386	Belongs to the glutathione peroxidase family
BB_RS14495	COG0625	glutathione transferase activity
BB_RS14510	COG0095	Lipoate-protein ligase
BB_RS14525	COG0688	phosphatidylethanolamine metabolic process
BB_RS14550	COG2363	Small membrane protein
BB_RS14555	COG0697	spore germination
BB_RS14565	COG2133	pyrroloquinoline quinone binding
BB_RS14570	COG0625	glutathione transferase activity
BB_RS14575	COG1794	racemase activity, acting on amino acids and derivatives
BB_RS14595	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS14605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BB_RS14615	COG1653	transport
BB_RS14620	COG1175	transmembrane transport
BB_RS14625	COG0395	ABC-type sugar transport system, permease component
BB_RS14630	COG3842	ATPase activity
BB_RS14645	COG0604	alcohol dehydrogenase
BB_RS14645	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS14645	COG3321	synthase
BB_RS14650	COG0156	8-amino-7-oxononanoate synthase activity
BB_RS14660	COG0300	oxidoreductase activity
BB_RS14680	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BB_RS14695	COG0438	transferase activity, transferring glycosyl groups
BB_RS14735	COG0783	Belongs to the Dps family
BB_RS14750	COG0583	DNA-binding transcription factor activity
BB_RS14755	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BB_RS14770	COG0656	L-ascorbic acid biosynthetic process
BB_RS14775	COG2814	Major facilitator Superfamily
BB_RS14780	COG0583	DNA-binding transcription factor activity
BB_RS14790	COG1840	ABC-type Fe3 transport system, periplasmic component
BB_RS14795	COG1178	ABC-type Fe3 transport system permease component
BB_RS14800	COG3842	ATPase activity
BB_RS14805	COG1741	Belongs to the pirin family
BB_RS14810	COG1741	Belongs to the pirin family
BB_RS14815	COG0583	DNA-binding transcription factor activity
BB_RS14820	COG2204	response regulator
BB_RS14830	COG0174	glutamine synthetase
BB_RS14835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BB_RS14840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BB_RS14845	COG5002	protein histidine kinase activity
BB_RS14845	COG5001	Diguanylate cyclase
BB_RS14875	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BB_RS14880	COG1561	YicC-like family, N-terminal region
BB_RS14900	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BB_RS14905	COG0791	NLP P60 protein
BB_RS14910	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS14915	COG2863	cytochrome
BB_RS14920	COG3258	Cytochrome c
BB_RS14925	COG0194	GDP metabolic process
BB_RS14930	COG1758	RNA polymerase activity
BB_RS14935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB_RS14940	COG1126	abc transporter atp-binding protein
BB_RS14945	COG0765	amino acid transport
BB_RS14950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS14970	COG0583	DNA-binding transcription factor activity
BB_RS14995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS15010	COG2831	hemolysin activation secretion protein
BB_RS15015	COG3539	Fimbrial protein
BB_RS15020	COG3188	usher protein
BB_RS15025	COG3121	Chaperone
BB_RS15035	COG3210	domain, Protein
BB_RS15035	COG3064	Membrane
BB_RS15035	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
BB_RS15040	COG2197	response regulator
BB_RS15045	COG2205	protein histidine kinase activity
BB_RS15045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS15055	COG4336	lyase activity
BB_RS15070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS15095	COG4181	ATPase activity
BB_RS15105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB_RS15110	COG0584	glycerophosphoryl diester phosphodiesterase
BB_RS15115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BB_RS15125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BB_RS15125	COG0678	peroxiredoxin activity
BB_RS15135	COG0789	Transcriptional regulator
BB_RS15140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BB_RS15175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BB_RS15180	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BB_RS15185	COG2252	PERMEase
BB_RS15190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BB_RS15195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB_RS15225	COG0488	(ABC) transporter
BB_RS15230	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS15240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS15245	COG1024	Enoyl-CoA hydratase
BB_RS15250	COG1619	proteins homologs of microcin C7 resistance protein MccF
BB_RS15255	COG0590	tRNA wobble adenosine to inosine editing
BB_RS15275	COG2212	antiporter activity
BB_RS15280	COG1863	multisubunit Na H antiporter MnhE subunit
BB_RS15285	COG0651	ATP synthesis coupled electron transport
BB_RS15290	COG1006	Multisubunit Na H antiporter MnhC subunit
BB_RS15295	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BB_RS15295	COG2111	Na H antiporter
BB_RS15300	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS15310	COG0420	3'-5' exonuclease activity
BB_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS15345	COG0395	ABC-type sugar transport system, permease component
BB_RS15355	COG3842	ATPase activity
BB_RS15385	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS15420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS15445	COG0602	queuosine metabolic process
BB_RS15450	COG0720	synthase
BB_RS15455	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS15460	COG0235	Class ii aldolase
BB_RS15485	COG1566	PFAM secretion protein HlyD family protein
BB_RS15495	COG0400	carboxylic ester hydrolase activity
BB_RS15510	COG0587	DNA-directed DNA polymerase activity
BB_RS15515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS15520	COG1959	2 iron, 2 sulfur cluster binding
BB_RS15560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BB_RS15575	COG0667	Aldo Keto reductase
BB_RS15585	COG5265	(ABC) transporter
BB_RS15620	COG3468	outer membrane autotransporter barrel domain protein
BB_RS15625	COG3468	outer membrane autotransporter barrel domain protein
BB_RS15650	COG0840	transmembrane signaling receptor activity
BB_RS15655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BB_RS15660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BB_RS15675	COG0833	amino acid
BB_RS15705	COG3829	transcription factor binding
BB_RS15715	COG4943	cyclic-guanylate-specific phosphodiesterase activity
BB_RS15730	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS15735	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS15740	COG0028	Belongs to the TPP enzyme family
BB_RS15755	COG0583	DNA-binding transcription factor activity
BB_RS15760	COG4692	amylo-alpha-1,6-glucosidase activity
BB_RS15770	COG0183	Belongs to the thiolase family
BB_RS15785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS15790	COG0633	Ferredoxin
BB_RS15800	COG1024	Enoyl-CoA hydratase
BB_RS15810	COG4638	Rieske (2fe-2S)
BB_RS15820	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS15870	COG4680	protein conserved in bacteria
BB_RS15880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB_RS15890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BB_RS15895	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BB_RS15900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BB_RS15910	COG0330	HflC and HflK could
BB_RS15915	COG0330	HflC and HflK could
BB_RS15920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB_RS15925	COG1923	regulation of RNA biosynthetic process
BB_RS15930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB_RS15935	COG1160	GTP binding
BB_RS15940	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB_RS15945	COG2976	Protein conserved in bacteria
BB_RS15965	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BB_RS15970	COG0105	UTP biosynthetic process
BB_RS15975	COG0525	valine-tRNA ligase activity
BB_RS15990	COG0642	Histidine kinase
BB_RS16000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB_RS16015	COG0228	four-way junction DNA binding
BB_RS16025	COG0425	Belongs to the sulfur carrier protein TusA family
BB_RS16030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BB_RS16080	COG4172	Belongs to the ABC transporter superfamily
BB_RS16085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS16090	COG0601	transmembrane transport
BB_RS16095	COG0747	negative chemotaxis
BB_RS16120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS16145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BB_RS16150	COG3395	kinase activity
BB_RS16160	COG5285	phytanoyl-CoA dioxygenase
BB_RS16175	COG0456	acetyltransferase
BB_RS16190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB_RS16195	COG2358	TRAP transporter, solute receptor (TAXI family
BB_RS16205	COG2311	Membrane
BB_RS16230	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BB_RS16240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BB_RS16245	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BB_RS16250	COG1760	l-serine dehydratase
BB_RS16255	COG1283	sodium-dependent phosphate transmembrane transporter activity
BB_RS16260	COG0412	Dienelactone hydrolase
BB_RS16275	COG1611	Belongs to the LOG family
BB_RS16295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BB_RS16300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BB_RS16305	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BB_RS16310	COG0195	Participates in both transcription termination and antitermination
BB_RS16310	COG2251	uridine kinase activity
BB_RS16315	COG0779	Required for maturation of 30S ribosomal subunits
BB_RS16320	COG1187	pseudouridine synthase activity
BB_RS16325	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BB_RS16335	COG0583	DNA-binding transcription factor activity
BB_RS16345	COG0523	cobalamin synthesis protein
BB_RS16365	COG0625	glutathione transferase activity
BB_RS16370	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BB_RS16375	COG1047	Peptidyl-prolyl cis-trans
BB_RS16380	COG2003	Belongs to the UPF0758 family
BB_RS16385	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BB_RS16390	COG3483	tryptophan 2,3-dioxygenase activity
BB_RS16405	COG0534	Mate efflux family protein
BB_RS16425	COG2304	oxidoreductase activity
BB_RS16440	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS16445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB_RS16450	COG1562	ergosterol biosynthetic process
BB_RS16455	COG1562	ergosterol biosynthetic process
BB_RS16460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BB_RS16460	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BB_RS16465	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BB_RS16475	COG0842	Transport permease protein
BB_RS16480	COG1131	(ABC) transporter
BB_RS16500	COG1477	protein flavinylation
BB_RS16515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BB_RS16530	COG5564	TIM-barrel signal transduction protein
BB_RS16535	COG5441	Belongs to the UPF0261 family
BB_RS16545	COG3468	outer membrane autotransporter barrel domain protein
BB_RS16550	COG3468	outer membrane autotransporter barrel domain protein
BB_RS16555	COG0542	response to heat
BB_RS16560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB_RS16575	COG0494	nUDIX hydrolase
BB_RS16580	COG3530	Putative quorum-sensing-regulated virulence factor
BB_RS16590	COG1595	DNA-templated transcription, initiation
BB_RS16595	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS16630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS16635	COG0765	amino acid transport
BB_RS16640	COG0765	amino acid transport
BB_RS16665	COG2841	Protein conserved in bacteria
BB_RS16670	COG2814	Major facilitator Superfamily
BB_RS16685	COG0628	permease
BB_RS16690	COG0842	Transport permease protein
BB_RS16695	COG1131	(ABC) transporter
BB_RS16740	COG3278	Belongs to the heme-copper respiratory oxidase family
BB_RS16760	COG0156	8-amino-7-oxononanoate synthase activity
BB_RS16770	COG4106	trans-aconitate 2-methyltransferase activity
BB_RS16770	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BB_RS16775	COG1380	Effector of murein hydrolase LrgA
BB_RS16780	COG1346	cytolysis
BB_RS16790	COG2224	Isocitrate lyase
BB_RS16795	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB_RS16795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BB_RS16805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB_RS16820	COG0736	holo-[acyl-carrier-protein] synthase activity
BB_RS16825	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BB_RS16835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB_RS16840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS16865	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BB_RS16880	COG2032	superoxide dismutase activity
BB_RS16890	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS16895	COG1024	Enoyl-CoA hydratase
BB_RS16905	COG1802	Transcriptional regulator
BB_RS16915	COG0183	Belongs to the thiolase family
BB_RS16920	COG1942	4-Oxalocrotonate Tautomerase
BB_RS16930	COG4176	ABC-type proline glycine betaine transport system permease component
BB_RS16940	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB_RS16945	COG2814	Major facilitator Superfamily
BB_RS16950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BB_RS16955	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB_RS16975	COG2814	Major facilitator Superfamily
BB_RS16980	COG0495	leucyl-tRNA aminoacylation
BB_RS16995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BB_RS17005	COG0154	amidase activity
BB_RS17010	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS17020	COG3012	SEC-C Motif Domain Protein
BB_RS17050	COG1530	ribonuclease E activity
BB_RS17055	COG0077	Prephenate dehydratase
BB_RS17070	COG1132	(ABC) transporter
BB_RS17075	COG0859	PFAM glycosyl transferase family 9
BB_RS17100	COG2194	sulfuric ester hydrolase activity
BB_RS17105	COG0438	transferase activity, transferring glycosyl groups
BB_RS17110	COG0463	Glycosyl transferase, family 2
BB_RS17115	COG0726	polysaccharide deacetylase
BB_RS17120	COG0438	transferase activity, transferring glycosyl groups
BB_RS17135	COG1643	Atp-dependent helicase
BB_RS17140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BB_RS17140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB_RS17145	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BB_RS17155	COG0704	Plays a role in the regulation of phosphate uptake
BB_RS17160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BB_RS17165	COG1960	acyl-CoA dehydrogenase activity
BB_RS17190	COG1177	transmembrane transport
BB_RS17195	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB_RS17200	COG3842	ATPase activity
BB_RS17205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BB_RS17220	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BB_RS17225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS17235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS17235	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS17240	COG3539	Fimbrial protein
BB_RS17245	COG3539	Fimbrial protein
BB_RS17250	COG3539	Fimbrial protein
BB_RS17260	COG2050	protein possibly involved in aromatic compounds catabolism
BB_RS17265	COG1024	Enoyl-CoA hydratase
BB_RS17270	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS17275	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BB_RS17280	COG2151	metal-sulfur cluster biosynthetic enzyme
BB_RS17285	COG3396	Phenylacetate-CoA oxygenase
BB_RS17290	COG3460	Phenylacetate-CoA oxygenase
BB_RS17295	COG3396	Phenylacetate-CoA oxygenase
BB_RS17300	COG3327	negative regulation of DNA-templated transcription, initiation
BB_RS17305	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BB_RS17310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BB_RS17315	COG0501	Belongs to the peptidase M48B family
BB_RS17320	COG1162	GTPase activity
BB_RS17325	COG0667	Aldo Keto reductase
BB_RS17335	COG0335	large ribosomal subunit rRNA binding
BB_RS17365	COG0175	sulfate reduction
BB_RS17370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BB_RS17375	COG4208	sulfate ABC transporter
BB_RS17390	COG0450	alkyl hydroperoxide reductase
BB_RS17395	COG1960	acyl-CoA dehydrogenase activity
BB_RS17410	COG0123	including yeast histone deacetylase and acetoin utilization protein
BB_RS17415	COG2951	lytic endotransglycosylase activity
BB_RS17435	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB_RS17440	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BB_RS17460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BB_RS17465	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BB_RS17470	COG0287	Prephenate dehydrogenase
BB_RS17495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BB_RS17505	COG2814	Major facilitator Superfamily
BB_RS17510	COG2135	peptidase activity
BB_RS17560	COG1196	nuclear chromosome segregation
BB_RS17775	COG0582	viral genome integration into host DNA
BB_RS17780	COG0583	DNA-binding transcription factor activity
BB_RS17820	COG0583	DNA-binding transcription factor activity
BB_RS17835	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB_RS17860	COG1053	succinate dehydrogenase
BB_RS17865	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS17870	COG2079	MmgE PrpD family protein
BB_RS17880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS17895	COG0583	DNA-binding transcription factor activity
BB_RS17905	COG0028	Belongs to the TPP enzyme family
BB_RS17905	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
BB_RS17910	COG0436	Aminotransferase
BB_RS17930	COG0778	Nitroreductase
BB_RS17935	COG2814	Major facilitator Superfamily
BB_RS17940	COG3706	GGDEF domain
BB_RS17945	COG0589	response to stress
BB_RS17955	COG2951	lytic endotransglycosylase activity
BB_RS17960	COG2833	Protein of unknown function (DUF455)
BB_RS17975	COG1132	(ABC) transporter
BB_RS17980	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB_RS17980	COG0189	ligase activity
BB_RS17985	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB_RS17985	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB_RS17990	COG3237	CsbD-like
BB_RS18000	COG2823	Periplasmic or secreted lipoprotein
BB_RS18015	COG0672	)-iron permease
BB_RS18030	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BB_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS18040	COG3243	poly(R)-hydroxyalkanoic acid synthase
BB_RS18050	COG0564	pseudouridine synthase activity
BB_RS18060	COG1199	ATP-dependent helicase activity
BB_RS18065	COG2183	response to ionizing radiation
BB_RS18140	COG4228	DNA circulation
BB_RS18205	COG2369	cell adhesion
BB_RS18215	COG4373	Mu-like prophage FluMu protein gp28
BB_RS18225	COG0640	Transcriptional regulator
BB_RS18305	COG0776	regulation of translation
BB_RS18330	COG4774	siderophore transport
BB_RS18335	COG3712	iron ion homeostasis
BB_RS18340	COG1595	DNA-templated transcription, initiation
BB_RS18345	COG2175	clavaminate synthase activity
BB_RS18355	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS18360	COG0583	DNA-binding transcription factor activity
BB_RS18365	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS18370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BB_RS18375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB_RS18380	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB_RS18385	COG0567	Dehydrogenase, E1 component
BB_RS18390	COG1297	OPT oligopeptide transporter protein
BB_RS18395	COG1522	sequence-specific DNA binding
BB_RS18405	COG0280	phosphate acetyltransferase
BB_RS18405	COG0281	malic enzyme
BB_RS18410	COG3539	Fimbrial protein
BB_RS18425	COG0372	Belongs to the citrate synthase family
BB_RS18430	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BB_RS18435	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BB_RS18440	COG1053	succinate dehydrogenase
BB_RS18445	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BB_RS18450	COG2009	succinate dehydrogenase
BB_RS18455	COG2188	Transcriptional regulator
BB_RS18460	COG0039	L-malate dehydrogenase activity
BB_RS18480	COG2828	Protein conserved in bacteria
BB_RS18490	COG1981	membrane
BB_RS18515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB_RS18525	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BB_RS18555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BB_RS18560	COG0148	phosphopyruvate hydratase activity
BB_RS18570	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BB_RS18575	COG0504	CTP synthase activity
BB_RS18595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS18605	COG0747	negative chemotaxis
BB_RS18610	COG4172	Belongs to the ABC transporter superfamily
BB_RS18615	COG1446	asparaginase
BB_RS18645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BB_RS18660	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BB_RS18665	COG0697	spore germination
BB_RS18670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB_RS18680	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BB_RS18685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BB_RS18690	COG0791	NLP P60 protein
BB_RS18700	COG0583	DNA-binding transcription factor activity
BB_RS18715	COG0583	DNA-binding transcription factor activity
BB_RS18725	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BB_RS18740	COG0670	Belongs to the BI1 family
BB_RS18755	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BB_RS18765	COG1381	Involved in DNA repair and RecF pathway recombination
BB_RS18770	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BB_RS18775	COG0571	ribonuclease III activity
BB_RS18780	COG0681	Belongs to the peptidase S26 family
BB_RS18790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BB_RS18815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BB_RS18820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BB_RS18835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB_RS18845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BB_RS18850	COG1399	metal-binding, possibly nucleic acid-binding protein
BB_RS18865	COG3023	N-Acetylmuramoyl-L-alanine amidase
BB_RS18875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BB_RS18880	COG0546	phosphoglycolate phosphatase activity
BB_RS18890	COG1530	ribonuclease E activity
BB_RS18900	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BB_RS18905	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BB_RS18910	COG0159	tryptophan synthase activity
BB_RS18925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB_RS18930	COG3228	Belongs to the MtfA family
BB_RS18940	COG0251	oxidation-reduction process
BB_RS18945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BB_RS18950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BB_RS18965	COG2878	Part of a membrane complex involved in electron transport
BB_RS18970	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BB_RS19005	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB_RS19030	COG1268	BioY protein
BB_RS19035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BB_RS19040	COG1122	ATPase activity
BB_RS19045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB_RS19055	COG0271	Belongs to the BolA IbaG family
BB_RS19060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB_RS19065	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BB_RS19075	COG1196	nuclear chromosome segregation
BB_RS19080	COG0477	Major facilitator Superfamily
BB_RS19085	COG1573	uracil-dna glycosylase
BB_RS19090	COG1214	PFAM Peptidase M22, glycoprotease
BB_RS19105	COG0450	alkyl hydroperoxide reductase
BB_RS19110	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS19120	COG2223	nitrite transmembrane transporter activity
BB_RS19125	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BB_RS19130	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BB_RS19135	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BB_RS19140	COG0560	Phosphoserine phosphatase
BB_RS19145	COG0583	DNA-binding transcription factor activity
BB_RS19150	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS19155	COG0028	Belongs to the TPP enzyme family
BB_RS19170	COG4774	siderophore transport
BB_RS19175	COG4774	siderophore transport
BB_RS19185	COG1007	ATP synthesis coupled electron transport
BB_RS19200	COG0713	ATP synthesis coupled electron transport
BB_RS19210	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB_RS19215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BB_RS19220	COG1034	ATP synthesis coupled electron transport
BB_RS19230	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BB_RS19240	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB_RS19245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB_RS19250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BB_RS19255	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB_RS19275	COG0671	phosphoesterase, PA-phosphatase related
BB_RS19285	COG1597	lipid kinase activity
BB_RS19290	COG0583	DNA-binding transcription factor activity
BB_RS19295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB_RS19300	COG1733	regulation of RNA biosynthetic process
BB_RS19305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS19310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB_RS19325	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BB_RS19345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS19365	COG3608	succinylglutamate desuccinylase aspartoacylase
BB_RS19370	COG0626	cystathionine gamma-synthase activity
BB_RS19375	COG0583	DNA-binding transcription factor activity
BB_RS19385	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS19390	COG0165	Argininosuccinate lyase
BB_RS19405	COG3799	methylaspartate ammonia-lyase activity
BB_RS19415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BB_RS19425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB_RS19430	COG0149	triose-phosphate isomerase activity
BB_RS19450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB_RS19460	COG1185	polyribonucleotide nucleotidyltransferase activity
BB_RS19465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BB_RS19475	COG1183	phosphatidylcholine synthase activity
BB_RS19485	COG0440	acetolactate synthase activity
BB_RS19490	COG0028	Belongs to the TPP enzyme family
BB_RS19495	COG1289	transmembrane transporter activity
BB_RS19505	COG3022	response to hydroperoxide
BB_RS19510	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS19525	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BB_RS19575	COG3706	GGDEF domain
BB_RS19605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BB_RS19610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BB_RS19615	COG1674	ftsk spoiiie
BB_RS19620	COG0492	ferredoxin-NADP+ reductase activity
BB_RS19625	COG1193	negative regulation of DNA recombination
BB_RS19635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB_RS19645	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BB_RS19650	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BB_RS19655	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BB_RS19660	COG2205	protein histidine kinase activity
BB_RS19665	COG0745	RESPONSE REGULATOR receiver
BB_RS19700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB_RS19720	COG0612	Peptidase, M16
BB_RS19725	COG0484	heat shock protein binding
BB_RS19730	COG0443	Heat shock 70 kDa protein
BB_RS19740	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BB_RS19750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BB_RS19755	COG1420	regulation of RNA biosynthetic process
BB_RS19765	COG0497	DNA recombination
BB_RS19770	COG0735	belongs to the Fur family
BB_RS19775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BB_RS19785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB_RS19795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS19800	COG2030	dehydratase
BB_RS19810	COG1024	Enoyl-CoA hydratase
BB_RS19835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BB_RS19845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BB_RS19845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BB_RS19860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BB_RS19865	COG0730	response to heat
BB_RS19875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS19885	COG0405	Gamma-glutamyltransferase
BB_RS19900	COG1280	lysine exporter protein (LysE YggA)
BB_RS19930	COG0583	DNA-binding transcription factor activity
BB_RS19940	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BB_RS19945	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BB_RS19950	COG0167	dihydroorotate dehydrogenase activity
BB_RS19970	COG1414	Transcriptional regulator
BB_RS19975	COG1546	Belongs to the CinA family
BB_RS19975	COG1058	Belongs to the CinA family
BB_RS19990	COG0513	Belongs to the DEAD box helicase family
BB_RS20020	COG0429	hydrolase of the alpha beta-hydrolase fold
BB_RS20025	COG4783	chaperone-mediated protein folding
BB_RS20040	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB_RS20055	COG0006	proline dipeptidase activity
BB_RS20065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB_RS20085	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BB_RS20090	COG0632	four-way junction helicase activity
BB_RS20105	COG2255	four-way junction helicase activity
BB_RS20110	COG0514	ATP-dependent DNA helicase (RecQ)
BB_RS20135	COG1271	oxidase subunit
BB_RS20140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB_RS20145	COG0850	regulation of cytokinetic process
BB_RS20150	COG2894	cell division
BB_RS20155	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BB_RS20170	COG0488	(ABC) transporter
BB_RS20195	COG4608	Belongs to the ABC transporter superfamily
BB_RS20200	COG0444	Belongs to the ABC transporter superfamily
BB_RS20205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS20210	COG0601	transmembrane transport
BB_RS20220	COG1215	transferase activity, transferring glycosyl groups
BB_RS20235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB_RS20245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB_RS20260	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS20265	COG2188	Transcriptional regulator
BB_RS20270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BB_RS20275	COG2814	Major facilitator Superfamily
BB_RS20285	COG0259	pyridoxamine-phosphate oxidase activity
BB_RS20290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BB_RS20305	COG0583	DNA-binding transcription factor activity
BB_RS20310	COG1960	acyl-CoA dehydrogenase activity
BB_RS20315	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS20320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS20325	COG0405	Gamma-glutamyltransferase
BB_RS20335	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS20350	COG0802	atpase or kinase
BB_RS20355	COG0860	N-Acetylmuramoyl-L-alanine amidase
BB_RS20360	COG0586	Pfam SNARE associated Golgi protein
BB_RS20365	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BB_RS20370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BB_RS20375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BB_RS20390	COG0617	tRNA 3'-terminal CCA addition
BB_RS20415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS20420	COG2188	Transcriptional regulator
BB_RS20430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BB_RS20435	COG1234	tRNA 3'-trailer cleavage
BB_RS20440	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS20450	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS20455	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS20460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB_RS20465	COG2301	Belongs to the HpcH HpaI aldolase family
BB_RS20470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS20475	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BB_RS20485	COG1024	Enoyl-CoA hydratase
BB_RS20495	COG2188	Transcriptional regulator
BB_RS20500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BB_RS20505	COG0066	3-isopropylmalate dehydratase activity
BB_RS20520	COG0752	glycyl-tRNA synthetase alpha subunit
BB_RS20525	COG0751	glycine-tRNA ligase activity
BB_RS20530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BB_RS20535	COG0204	Acyl-transferase
BB_RS20550	COG0242	peptide deformylase activity
BB_RS20560	COG0700	Nucleoside recognition
BB_RS20565	COG0469	pyruvate kinase activity
BB_RS20570	COG1929	Belongs to the glycerate kinase type-1 family
BB_RS20575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BB_RS20580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BB_RS20585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BB_RS20595	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BB_RS20605	COG2154	pterin-4-alpha-carbinolamine dehydratase
BB_RS20625	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BB_RS20630	COG0154	amidase activity
BB_RS20640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS20645	COG0601	transmembrane transport
BB_RS20650	COG0747	negative chemotaxis
BB_RS20670	COG0019	diaminopimelate decarboxylase activity
BB_RS20685	COG3712	iron ion homeostasis
BB_RS20690	COG4774	siderophore transport
BB_RS20695	COG2353	YceI-like domain
BB_RS20700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB_RS20715	COG0583	DNA-binding transcription factor activity
BB_RS20735	COG3384	dioxygenase
BB_RS20740	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB_RS20820	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS20825	COG1309	transcriptional regulator
BB_RS20830	COG2982	Protein involved in outer membrane biogenesis
BB_RS20835	COG2818	Glycosylase
BB_RS20855	COG1653	transport
BB_RS20860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB_RS20865	COG3842	ATPase activity
BB_RS20870	COG0395	ABC-type sugar transport system, permease component
BB_RS20875	COG1175	transmembrane transport
BB_RS20890	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS20895	COG2186	Transcriptional regulator
BB_RS20915	COG1454	alcohol dehydrogenase
BB_RS20930	COG2011	ABC-type metal ion transport system permease component
BB_RS20935	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BB_RS20940	COG1501	Belongs to the glycosyl hydrolase 31 family
BB_RS20945	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BB_RS20945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS20955	COG0318	PFAM AMP-dependent synthetase and ligase
BB_RS20960	COG1473	amidohydrolase
BB_RS20970	COG2855	membrane
BB_RS20980	COG2239	Acts as a magnesium transporter
BB_RS20995	COG1522	sequence-specific DNA binding
BB_RS21000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS21005	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS21025	COG0653	protein targeting
BB_RS21030	COG0739	heme binding
BB_RS21040	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BB_RS21045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BB_RS21055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BB_RS21060	COG1181	Belongs to the D-alanine--D-alanine ligase family
BB_RS21070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BB_RS21080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BB_RS21085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB_RS21090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BB_RS21100	COG3116	cell division
BB_RS21105	COG0275	rRNA processing
BB_RS21110	COG2001	Belongs to the MraZ family
BB_RS21115	COG0488	(ABC) transporter
BB_RS21120	COG0418	dihydroorotase activity
BB_RS21125	COG1473	amidohydrolase
BB_RS21175	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BB_RS21180	COG4654	Cytochrome c, class I
BB_RS21185	COG0129	dihydroxy-acid dehydratase activity
BB_RS21190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BB_RS21225	COG2084	Dehydrogenase
BB_RS21230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BB_RS21260	COG0494	nUDIX hydrolase
BB_RS21265	COG0442	prolyl-tRNA aminoacylation
BB_RS21270	COG0824	Thioesterase
BB_RS21275	COG0811	peptide transport
BB_RS21280	COG0848	biopolymer transport protein
BB_RS21290	COG0823	Involved in the tonB-independent uptake of proteins
BB_RS21305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB_RS21310	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BB_RS21315	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS21330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BB_RS21355	COG0183	Belongs to the thiolase family
BB_RS21365	COG1960	acyl-CoA dehydrogenase activity
BB_RS21370	COG0583	DNA-binding transcription factor activity
BB_RS21375	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS21380	COG1024	Enoyl-CoA hydratase
BB_RS21385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS21390	COG1253	flavin adenine dinucleotide binding
BB_RS21395	COG1285	pathogenesis
BB_RS21400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BB_RS21415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB_RS21420	COG0697	spore germination
BB_RS21445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BB_RS21450	COG0463	Glycosyl transferase, family 2
BB_RS21460	COG0786	glutamate:sodium symporter activity
BB_RS21470	COG2031	fatty acid transporter
BB_RS21485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BB_RS21490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BB_RS21495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BB_RS21500	COG0328	RNA-DNA hybrid ribonuclease activity
BB_RS21505	COG2226	methyltransferase
BB_RS21510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB_RS21515	COG1388	LysM domain
BB_RS21515	COG0741	lytic transglycosylase activity
BB_RS21530	COG2979	Protein of unknown function (DUF533)
BB_RS21610	COG2816	NAD+ diphosphatase activity
BB_RS21615	COG1309	transcriptional regulator
BB_RS21620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS21635	COG1024	Enoyl-CoA hydratase
BB_RS21650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS21665	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS21680	COG3119	arylsulfatase activity
BB_RS21705	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BB_RS21720	COG0804	urea catabolic process
BB_RS21725	COG0832	Belongs to the urease beta subunit family
BB_RS21735	COG0831	urea catabolic process
BB_RS21740	COG0829	nickel cation binding
BB_RS21745	COG0583	DNA-binding transcription factor activity
BB_RS21750	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS21775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS21790	COG2188	Transcriptional regulator
BB_RS21815	COG2719	SpoVR family
BB_RS21820	COG2718	Belongs to the UPF0229 family
BB_RS21825	COG2766	serine protein kinase
BB_RS21830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB_RS21830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BB_RS21840	COG4977	sequence-specific DNA binding
BB_RS21845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB_RS21850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BB_RS21860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BB_RS21875	COG0316	Belongs to the HesB IscA family
BB_RS21890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BB_RS21895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BB_RS21900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BB_RS21905	COG0312	modulator of DNA gyrase
BB_RS21925	COG1116	anion transmembrane transporter activity
BB_RS21930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS21935	COG1335	isochorismatase
BB_RS21940	COG0346	lactoylglutathione lyase activity
BB_RS21945	COG0513	Belongs to the DEAD box helicase family
BB_RS21950	COG3069	C4-dicarboxylate transmembrane transporter activity
BB_RS21955	COG1802	Transcriptional regulator
BB_RS21960	COG1042	CoA-binding domain protein
BB_RS21960	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB_RS21960	COG0045	succinate-CoA ligase (ADP-forming) activity
BB_RS21965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB_RS21980	COG1522	sequence-specific DNA binding
BB_RS22010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BB_RS22015	COG1696	Membrane protein involved in D-alanine export
BB_RS22040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB_RS22050	COG2264	protein methyltransferase activity
BB_RS22055	COG0439	Biotin carboxylase
BB_RS22060	COG0511	ligase activity, forming carbon-carbon bonds
BB_RS22065	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB_RS22070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BB_RS22075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BB_RS22080	COG3150	esterase
BB_RS22085	COG0557	exoribonuclease II activity
BB_RS22095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB_RS22100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB_RS22125	COG0540	Belongs to the ATCase OTCase family
BB_RS22135	COG1678	Uncharacterized ACR, COG1678
BB_RS22150	COG0352	thiamine-phosphate diphosphorylase activity
BB_RS22155	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BB_RS22180	COG1960	acyl-CoA dehydrogenase activity
BB_RS22185	COG1024	Enoyl-CoA hydratase
BB_RS22190	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS22250	COG0494	nUDIX hydrolase
BB_RS22275	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BB_RS22285	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BB_RS22300	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BB_RS22305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB_RS22315	COG0477	Major facilitator Superfamily
BB_RS22335	COG1126	abc transporter atp-binding protein
BB_RS22340	COG0765	amino acid transport
BB_RS22345	COG4597	amino acid ABC transporter
BB_RS22350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS22355	COG2884	Cell division ATP-binding protein ftsE
BB_RS22360	COG2177	Part of the ABC transporter FtsEX involved in
BB_RS22365	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BB_RS22375	COG1194	a g-specific adenine glycosylase
BB_RS22385	COG2226	methyltransferase
BB_RS22395	COG4206	TonB-dependent receptor
BB_RS22400	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BB_RS22405	COG2022	thiamine diphosphate biosynthetic process
BB_RS22410	COG0351	phosphomethylpyrimidine kinase
BB_RS22415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BB_RS22425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB_RS22435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BB_RS22450	COG2226	methyltransferase
BB_RS22455	COG0745	RESPONSE REGULATOR receiver
BB_RS22460	COG5002	protein histidine kinase activity
BB_RS22470	COG5002	protein histidine kinase activity
BB_RS22480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB_RS22485	COG0583	DNA-binding transcription factor activity
BB_RS22495	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB_RS22500	COG1984	allophanate hydrolase subunit 2
BB_RS22515	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS22525	COG1024	Enoyl-CoA hydratase
BB_RS22530	COG0657	acetylesterase activity
BB_RS22540	COG1802	Transcriptional regulator
BB_RS22550	COG1238	metal cluster binding
BB_RS22555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB_RS22560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB_RS22580	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BB_RS22585	COG4988	ABC transporter
BB_RS22595	COG1294	oxidase, subunit
BB_RS22610	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BB_RS22620	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BB_RS22635	COG1137	ATPase activity
BB_RS22640	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB_RS22655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BB_RS22655	COG2010	Cytochrome c
BB_RS22665	COG1660	Displays ATPase and GTPase activities
BB_RS22675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB_RS22685	COG0792	nuclease activity
BB_RS22690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BB_RS22695	COG2823	Periplasmic or secreted lipoprotein
BB_RS22710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BB_RS22720	COG1309	transcriptional regulator
BB_RS22725	COG0471	metal ion transport
BB_RS22730	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB_RS22735	COG0772	Belongs to the SEDS family
BB_RS22740	COG0768	penicillin binding
BB_RS22750	COG1792	Involved in formation and maintenance of cell shape
BB_RS22755	COG1077	Cell shape determining protein MreB Mrl
BB_RS22760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB_RS22765	COG0154	amidase activity
BB_RS22770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BB_RS22775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BB_RS22780	COG0708	Exodeoxyribonuclease III
BB_RS22785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB_RS22790	COG2860	membrane
BB_RS22800	COG0583	DNA-binding transcription factor activity
BB_RS22805	COG0473	3-isopropylmalate dehydrogenase activity
BB_RS22810	COG3391	amine dehydrogenase activity
BB_RS22830	COG0583	DNA-binding transcription factor activity
BB_RS22835	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BB_RS22840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB_RS22845	COG0765	amino acid transport
BB_RS22850	COG0765	amino acid transport
BB_RS22855	COG1126	abc transporter atp-binding protein
BB_RS22860	COG1794	racemase activity, acting on amino acids and derivatives
BB_RS22865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB_RS22870	COG2223	nitrite transmembrane transporter activity
BB_RS22875	COG2813	Specifically methylates the guanine in position
BB_RS22875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB_RS22880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BB_RS22885	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BB_RS22910	COG2918	glutathione biosynthetic process
BB_RS22930	COG0583	DNA-binding transcription factor activity
BB_RS22935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BB_RS22940	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BB_RS22985	COG1414	Transcriptional regulator
BB_RS23005	COG2132	Multicopper oxidase
BB_RS23025	COG1250	3-hydroxyacyl-CoA dehydrogenase
BB_RS23050	COG1024	Enoyl-CoA hydratase
BB_RS23055	COG1024	Enoyl-CoA hydratase
BB_RS23060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BB_RS23070	COG0747	negative chemotaxis
BB_RS23080	COG0601	transmembrane transport
BB_RS23085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS23090	COG0444	Belongs to the ABC transporter superfamily
BB_RS23095	COG4608	Belongs to the ABC transporter superfamily
BB_RS23105	COG2195	Cleaves the N-terminal amino acid of tripeptides
BB_RS23110	COG0210	DNA helicase
BB_RS23115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB_RS23120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BB_RS23130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB_RS23140	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BB_RS23150	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BB_RS23165	COG0356	it plays a direct role in the translocation of protons across the membrane
BB_RS23180	COG1024	Enoyl-CoA hydratase
BB_RS23200	COG0037	tRNA processing
BB_RS23205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB_RS23215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BB_RS23220	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BB_RS23225	COG2967	ApaG domain
BB_RS23230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB_RS23235	COG0546	phosphoglycolate phosphatase activity
BB_RS23245	COG0512	Glutamine amidotransferase of anthranilate synthase
BB_RS23260	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS23280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BB_RS23290	COG1607	acyl-coa hydrolase
BB_RS23335	COG3069	C4-dicarboxylate transmembrane transporter activity
BB_RS23345	COG1802	Transcriptional regulator
BB_RS23375	COG1595	DNA-templated transcription, initiation
BB_RS23380	COG3712	iron ion homeostasis
BB_RS23390	COG3720	iron ion transport
BB_RS23395	COG4558	Periplasmic binding protein
BB_RS23400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BB_RS23405	COG1120	ATPase activity
BB_RS23410	COG1683	Conserved Protein
BB_RS23440	COG3064	Membrane
BB_RS23445	COG0583	DNA-binding transcription factor activity
BB_RS23455	COG1234	tRNA 3'-trailer cleavage
BB_RS23465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BB_RS23470	COG1802	Transcriptional regulator
BB_RS23480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB_RS23485	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS23500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23520	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS23535	COG2186	Transcriptional regulator
BB_RS23540	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS23545	COG4948	Mandelate Racemase Muconate Lactonizing
BB_RS23565	COG1053	succinate dehydrogenase
BB_RS23570	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS23585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB_RS23595	COG0411	ABC transporter
BB_RS23600	COG0559	Belongs to the binding-protein-dependent transport system permease family
BB_RS23625	COG0508	dehydrogenase complex catalyzes the overall conversion of
BB_RS23630	COG1024	Enoyl-CoA hydratase
BB_RS23635	COG0022	dehydrogenase e1 component
BB_RS23640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BB_RS23665	COG1960	acyl-CoA dehydrogenase activity
BB_RS23670	COG1024	Enoyl-CoA hydratase
BB_RS23675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BB_RS23695	COG1960	acyl-CoA dehydrogenase activity
BB_RS23700	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS23705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB_RS23730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BB_RS23735	COG1984	allophanate hydrolase subunit 2
BB_RS23740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BB_RS23745	COG0747	negative chemotaxis
BB_RS23750	COG0601	transmembrane transport
BB_RS23755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS23785	COG0511	ligase activity, forming carbon-carbon bonds
BB_RS23790	COG0439	Biotin carboxylase
BB_RS23805	COG0709	Synthesizes selenophosphate from selenide and ATP
BB_RS23810	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BB_RS23845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23855	COG0604	alcohol dehydrogenase
BB_RS23865	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS23875	COG1960	acyl-CoA dehydrogenase activity
BB_RS23880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23885	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS23890	COG1024	Enoyl-CoA hydratase
BB_RS23895	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB_RS23895	COG1902	pentaerythritol trinitrate reductase activity
BB_RS23900	COG1024	Enoyl-CoA hydratase
BB_RS23905	COG1846	Transcriptional regulator
BB_RS23920	COG4771	TonB-dependent receptor
BB_RS23935	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS23940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23945	COG0183	Belongs to the thiolase family
BB_RS23950	COG2030	dehydratase
BB_RS23955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS23995	COG3842	ATPase activity
BB_RS24005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BB_RS24020	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
BB_RS24025	COG0583	DNA-binding transcription factor activity
BB_RS24040	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS24050	COG0277	FAD linked oxidase domain protein
BB_RS24055	COG1960	acyl-CoA dehydrogenase activity
BB_RS24060	COG1960	acyl-CoA dehydrogenase activity
BB_RS24070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB_RS24085	COG2072	flavoprotein involved in K transport
BB_RS24090	COG0604	alcohol dehydrogenase
BB_RS24105	COG1024	Enoyl-CoA hydratase
BB_RS24115	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS24130	COG1522	sequence-specific DNA binding
BB_RS24135	COG0183	Belongs to the thiolase family
BB_RS24145	COG1960	acyl-CoA dehydrogenase activity
BB_RS24180	COG3708	Transcriptional regulator
BB_RS24180	COG2207	Transcriptional regulator
BB_RS24195	COG2814	Major facilitator Superfamily
BB_RS24220	COG1999	signal sequence binding
BB_RS24265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BB_RS24285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB_RS24290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB_RS24300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BB_RS24305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BB_RS24315	COG0069	glutamate synthase activity
BB_RS24315	COG0067	glutamate synthase
BB_RS24315	COG0070	glutamate synthase
BB_RS24325	COG3047	cAMP biosynthetic process
BB_RS24335	COG1127	ABC transporter
BB_RS24340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BB_RS24345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BB_RS24350	COG2853	Lipoprotein
BB_RS24360	COG1131	(ABC) transporter
BB_RS24365	COG0842	Transport permease protein
BB_RS24375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB_RS24385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BB_RS24390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BB_RS24395	COG0131	Imidazoleglycerol-phosphate dehydratase
BB_RS24405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BB_RS24410	COG0107	imidazoleglycerol-phosphate synthase activity
BB_RS24420	COG0140	phosphoribosyl-ATP diphosphatase activity
BB_RS24425	COG0537	adenosine 5'-monophosphoramidase activity
BB_RS24430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB_RS24435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BB_RS24455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB_RS24460	COG1970	mechanosensitive ion channel activity
BB_RS24465	COG0723	plastoquinol--plastocyanin reductase activity
BB_RS24470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BB_RS24475	COG2857	Cytochrome c1
BB_RS24480	COG0625	glutathione transferase activity
BB_RS24485	COG2969	positive regulation of protein catabolic process
BB_RS24515	COG0583	DNA-binding transcription factor activity
BB_RS24520	COG0492	ferredoxin-NADP+ reductase activity
BB_RS24540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS24550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BB_RS24565	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS24600	COG3702	type iv secretory pathway
BB_RS24605	COG3451	type IV secretory pathway VirB4
BB_RS24620	COG3736	Type IV secretory pathway, component VirB8
BB_RS24630	COG2948	multi-organism process
BB_RS24635	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BB_RS24645	COG0697	spore germination
BB_RS24665	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BB_RS24670	COG0747	negative chemotaxis
BB_RS24675	COG0601	transmembrane transport
BB_RS24680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB_RS24690	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BB_RS24700	COG0513	Belongs to the DEAD box helicase family
BB_RS24705	COG1280	lysine exporter protein (LysE YggA)
BB_RS24710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BB_RS24730	COG0583	DNA-binding transcription factor activity
BB_RS24740	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BB_RS24750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BB_RS24755	COG0154	amidase activity
BB_RS24760	COG1609	Transcriptional regulator
BB_RS24780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BB_RS24785	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BB_RS24790	COG3842	ATPase activity
BB_RS24795	COG1653	transport
BB_RS24800	COG1175	transmembrane transport
BB_RS24805	COG0395	ABC-type sugar transport system, permease component
BB_RS24820	COG0018	arginyl-trna synthetase
BB_RS24840	COG1280	lysine exporter protein (LysE YggA)
BB_RS24855	COG1960	acyl-CoA dehydrogenase activity
BB_RS24860	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BB_RS24865	COG0183	Belongs to the thiolase family
BB_RS24870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB_RS24885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BB_RS24890	COG3181	Tripartite tricarboxylate transporter family receptor
BB_RS24900	COG2358	TRAP transporter, solute receptor (TAXI family
BB_RS24910	COG1629	transport
BB_RS24915	COG2922	Belongs to the Smg family
BB_RS24920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BB_RS24940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB_RS24945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS24950	COG1028	Short-chain dehydrogenase reductase Sdr
BB_RS24955	COG1012	belongs to the aldehyde dehydrogenase family
BB_RS24965	COG0028	Belongs to the TPP enzyme family
BB_RS24970	COG1522	sequence-specific DNA binding
BB_RS24975	COG3781	membrane
BB_RS25005	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BB_RS25030	COG1304	FMN binding
BB_RS25045	COG0154	amidase activity
BB_RS25050	COG1414	Transcriptional regulator
BB_RS25075	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BB_RS25080	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BB_RS25085	COG0594	ribonuclease P activity
BB_RS25090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BB_RS25095	COG0706	membrane insertase activity
BB_RS25100	COG0753	catalase activity
BB_RS25105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB_RS25110	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BB_RS25120	COG2175	clavaminate synthase activity
BB_RS25125	COG1473	amidohydrolase
BB_RS25130	COG4608	Belongs to the ABC transporter superfamily
BB_RS25135	COG0444	Belongs to the ABC transporter superfamily
BB_RS25145	COG0601	transmembrane transport
BB_RS25150	COG0747	negative chemotaxis
BB_RS25155	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BB_RS25190	COG0436	Aminotransferase
BB_RS25195	COG1278	Cold shock
BB_RS25255	COG2801	Transposase and inactivated derivatives
BB_RS25260	COG1555	photosystem II stabilization
BB_RS25260	COG1596	polysaccharide export