locus-tag	class	description
CAL15_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAL15_RS00010	COG0592	DNA-directed DNA polymerase activity
CAL15_RS00030	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CAL15_RS00040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CAL15_RS00045	COG0463	Glycosyl transferase, family 2
CAL15_RS00070	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS00075	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00080	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00095	COG0154	amidase activity
CAL15_RS00110	COG0583	DNA-binding transcription factor activity
CAL15_RS00120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS00125	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00135	COG1024	Enoyl-CoA hydratase
CAL15_RS00145	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS00160	COG2188	Transcriptional regulator
CAL15_RS00170	COG3842	ATPase activity
CAL15_RS00175	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS00180	COG1177	transmembrane transport
CAL15_RS00210	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS00215	COG2721	sulfolactate sulfo-lyase activity
CAL15_RS00240	COG0402	S-adenosylhomocysteine deaminase activity
CAL15_RS00245	COG1079	Belongs to the binding-protein-dependent transport system permease family
CAL15_RS00250	COG4603	Belongs to the binding-protein-dependent transport system permease family
CAL15_RS00255	COG3845	ABC transporter
CAL15_RS00260	COG1744	ABC transporter substrate-binding protein PnrA-like
CAL15_RS00270	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL15_RS00275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL15_RS00295	COG1522	sequence-specific DNA binding
CAL15_RS00300	COG0028	Belongs to the TPP enzyme family
CAL15_RS00305	COG0154	amidase activity
CAL15_RS00310	COG1609	Transcriptional regulator
CAL15_RS00330	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL15_RS00335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL15_RS00340	COG3842	ATPase activity
CAL15_RS00345	COG1653	transport
CAL15_RS00355	COG0395	ABC-type sugar transport system, permease component
CAL15_RS00405	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00410	COG0183	Belongs to the thiolase family
CAL15_RS00415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAL15_RS00425	COG0183	Belongs to the thiolase family
CAL15_RS00430	COG1024	Enoyl-CoA hydratase
CAL15_RS00430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS00440	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS00460	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00465	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00470	COG1902	pentaerythritol trinitrate reductase activity
CAL15_RS00470	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAL15_RS00480	COG4221	oxidoreductase activity
CAL15_RS00480	COG3321	synthase
CAL15_RS00480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAL15_RS00480	COG0604	alcohol dehydrogenase
CAL15_RS00485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS00490	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS00495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS00505	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS00510	COG1024	Enoyl-CoA hydratase
CAL15_RS00515	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS00520	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CAL15_RS00525	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS00530	COG2204	response regulator
CAL15_RS00535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAL15_RS00550	COG2358	TRAP transporter, solute receptor (TAXI family
CAL15_RS00560	COG2922	Belongs to the Smg family
CAL15_RS00565	COG4774	siderophore transport
CAL15_RS00580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL15_RS00590	COG0551	DNA topoisomerase type I activity
CAL15_RS00590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAL15_RS00625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS00630	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS00635	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS00645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL15_RS00655	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL15_RS00665	COG0583	DNA-binding transcription factor activity
CAL15_RS00685	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CAL15_RS00690	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS00695	COG0513	Belongs to the DEAD box helicase family
CAL15_RS00705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS00710	COG0601	transmembrane transport
CAL15_RS00720	COG1160	GTP binding
CAL15_RS00725	COG2155	Conserved Protein
CAL15_RS00730	COG3047	cAMP biosynthetic process
CAL15_RS00740	COG0408	coproporphyrinogen oxidase activity
CAL15_RS00745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAL15_RS00765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS00770	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS00775	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS00780	COG0583	DNA-binding transcription factor activity
CAL15_RS00815	COG2969	positive regulation of protein catabolic process
CAL15_RS00820	COG0625	glutathione transferase activity
CAL15_RS00825	COG2857	Cytochrome c1
CAL15_RS00830	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAL15_RS00835	COG0723	plastoquinol--plastocyanin reductase activity
CAL15_RS00840	COG1970	mechanosensitive ion channel activity
CAL15_RS00845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAL15_RS00850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL15_RS00860	COG0805	protein transport
CAL15_RS00865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL15_RS00870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL15_RS00880	COG0140	phosphoribosyl-ATP diphosphatase activity
CAL15_RS00885	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CAL15_RS00890	COG0107	imidazoleglycerol-phosphate synthase activity
CAL15_RS00895	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAL15_RS00905	COG0131	Imidazoleglycerol-phosphate dehydratase
CAL15_RS00910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL15_RS00915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAL15_RS00925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAL15_RS00935	COG0842	Transport permease protein
CAL15_RS00940	COG1131	(ABC) transporter
CAL15_RS00950	COG2853	Lipoprotein
CAL15_RS00955	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL15_RS00960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL15_RS00965	COG1127	ABC transporter
CAL15_RS00975	COG0583	DNA-binding transcription factor activity
CAL15_RS00980	COG4221	oxidoreductase activity
CAL15_RS00985	COG0693	protein deglycase activity
CAL15_RS00995	COG0069	glutamate synthase activity
CAL15_RS00995	COG0070	glutamate synthase
CAL15_RS00995	COG0067	glutamate synthase
CAL15_RS01020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAL15_RS01025	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL15_RS01035	COG1609	Transcriptional regulator
CAL15_RS01040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL15_RS01045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS01050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS01055	COG0129	dihydroxy-acid dehydratase activity
CAL15_RS01070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL15_RS01100	COG1612	heme a metabolic process
CAL15_RS01110	COG1999	signal sequence binding
CAL15_RS01130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAL15_RS01135	COG2814	Major facilitator Superfamily
CAL15_RS01155	COG1522	sequence-specific DNA binding
CAL15_RS01170	COG3550	peptidyl-serine autophosphorylation
CAL15_RS01175	COG0583	DNA-binding transcription factor activity
CAL15_RS01220	COG1429	ligase activity, forming nitrogen-metal bonds
CAL15_RS01225	COG4771	TonB-dependent receptor
CAL15_RS01240	COG2197	response regulator
CAL15_RS01245	COG4585	Histidine kinase
CAL15_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS01275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL15_RS01280	COG0583	DNA-binding transcription factor activity
CAL15_RS01300	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS01305	COG1177	transmembrane transport
CAL15_RS01310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL15_RS01330	COG3842	ATPase activity
CAL15_RS01335	COG0489	protein tyrosine kinase activity
CAL15_RS01365	COG3383	formate dehydrogenase (NAD+) activity
CAL15_RS01365	COG0243	molybdopterin cofactor binding
CAL15_RS01370	COG0437	4 iron, 4 sulfur cluster binding
CAL15_RS01400	COG1122	ATPase activity
CAL15_RS01410	COG1763	Mo-molybdopterin cofactor biosynthetic process
CAL15_RS01420	COG0746	molybdenum cofactor guanylyltransferase activity
CAL15_RS01435	COG0463	Glycosyl transferase, family 2
CAL15_RS01440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL15_RS01455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CAL15_RS01460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAL15_RS01510	COG0154	amidase activity
CAL15_RS01520	COG0583	DNA-binding transcription factor activity
CAL15_RS01525	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS01565	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAL15_RS01580	COG1733	regulation of RNA biosynthetic process
CAL15_RS01600	COG1056	cytidyltransferase-related domain
CAL15_RS01600	COG1051	belongs to the nudix hydrolase family
CAL15_RS01605	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CAL15_RS01605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAL15_RS01615	COG1538	Outer membrane efflux protein
CAL15_RS01620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL15_RS01630	COG1309	transcriptional regulator
CAL15_RS01645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAL15_RS01660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL15_RS01680	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL15_RS01680	COG2169	Transcriptional regulator
CAL15_RS01695	COG1120	ATPase activity
CAL15_RS01700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAL15_RS01705	COG4558	Periplasmic binding protein
CAL15_RS01710	COG3720	iron ion transport
CAL15_RS01715	COG1607	acyl-coa hydrolase
CAL15_RS01720	COG0583	DNA-binding transcription factor activity
CAL15_RS01735	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS01750	COG3284	Transcriptional regulator
CAL15_RS01755	COG1278	Cold shock
CAL15_RS01760	COG0134	indole-3-glycerol-phosphate synthase activity
CAL15_RS01765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAL15_RS01770	COG0512	Glutamine amidotransferase of anthranilate synthase
CAL15_RS01790	COG0583	DNA-binding transcription factor activity
CAL15_RS01795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS01825	COG3220	belongs to the UPF0276 family
CAL15_RS01835	COG1595	DNA-templated transcription, initiation
CAL15_RS01840	COG4944	Protein of unknown function (DUF1109)
CAL15_RS01855	COG0546	phosphoglycolate phosphatase activity
CAL15_RS01860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CAL15_RS01865	COG2967	ApaG domain
CAL15_RS01870	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CAL15_RS01875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL15_RS01885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL15_RS01890	COG0037	tRNA processing
CAL15_RS01895	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CAL15_RS01900	COG0492	ferredoxin-NADP+ reductase activity
CAL15_RS01910	COG1024	Enoyl-CoA hydratase
CAL15_RS01925	COG0356	it plays a direct role in the translocation of protons across the membrane
CAL15_RS01935	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CAL15_RS01940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAL15_RS01950	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAL15_RS01955	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAL15_RS01960	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAL15_RS01970	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAL15_RS01975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAL15_RS01980	COG0210	DNA helicase
CAL15_RS01990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL15_RS02005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAL15_RS02015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAL15_RS02020	COG1024	Enoyl-CoA hydratase
CAL15_RS02025	COG1024	Enoyl-CoA hydratase
CAL15_RS02050	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS02055	COG3245	cytochrome
CAL15_RS02075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL15_RS02080	COG1304	FMN binding
CAL15_RS02085	COG2072	flavoprotein involved in K transport
CAL15_RS02235	COG2918	glutathione biosynthetic process
CAL15_RS02240	COG2267	carboxylic ester hydrolase activity
CAL15_RS02250	COG2197	response regulator
CAL15_RS02260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL15_RS02265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL15_RS02275	COG2721	sulfolactate sulfo-lyase activity
CAL15_RS02280	COG2721	sulfolactate sulfo-lyase activity
CAL15_RS02295	COG2813	Specifically methylates the guanine in position
CAL15_RS02295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL15_RS02305	COG2223	nitrite transmembrane transporter activity
CAL15_RS02310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS02315	COG0531	amino acid
CAL15_RS02320	COG2378	regulation of single-species biofilm formation
CAL15_RS02330	COG0708	Exodeoxyribonuclease III
CAL15_RS02335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAL15_RS02345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL15_RS02350	COG0154	amidase activity
CAL15_RS02355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL15_RS02360	COG1077	Cell shape determining protein MreB Mrl
CAL15_RS02365	COG1792	Involved in formation and maintenance of cell shape
CAL15_RS02375	COG0768	penicillin binding
CAL15_RS02380	COG0772	Belongs to the SEDS family
CAL15_RS02385	COG0471	metal ion transport
CAL15_RS02405	COG1309	transcriptional regulator
CAL15_RS02415	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL15_RS02425	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CAL15_RS02430	COG0784	Response regulator, receiver
CAL15_RS02430	COG4191	Histidine kinase
CAL15_RS02440	COG2823	Periplasmic or secreted lipoprotein
CAL15_RS02445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CAL15_RS02450	COG0792	nuclease activity
CAL15_RS02460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL15_RS02470	COG1660	Displays ATPase and GTPase activities
CAL15_RS02475	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAL15_RS02485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAL15_RS02490	COG1137	ATPase activity
CAL15_RS02515	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CAL15_RS02525	COG1271	oxidase subunit
CAL15_RS02530	COG1294	oxidase, subunit
CAL15_RS02540	COG4988	ABC transporter
CAL15_RS02545	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CAL15_RS02550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAL15_RS02560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL15_RS02575	COG1238	metal cluster binding
CAL15_RS02590	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS02595	COG0583	DNA-binding transcription factor activity
CAL15_RS02600	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS02605	COG0443	Heat shock 70 kDa protein
CAL15_RS02615	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS02615	COG3321	synthase
CAL15_RS02615	COG0604	alcohol dehydrogenase
CAL15_RS02620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CAL15_RS02625	COG0583	DNA-binding transcription factor activity
CAL15_RS02630	COG0668	transmembrane transport
CAL15_RS02660	COG2084	Dehydrogenase
CAL15_RS02685	COG0326	Molecular chaperone. Has ATPase activity
CAL15_RS02700	COG2271	Major facilitator Superfamily
CAL15_RS02705	COG4948	Mandelate Racemase Muconate Lactonizing
CAL15_RS02710	COG0800	Aldolase
CAL15_RS02715	COG3734	2-keto-3-deoxy-galactonokinase
CAL15_RS02720	COG1414	Transcriptional regulator
CAL15_RS02725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CAL15_RS02730	COG0625	glutathione transferase activity
CAL15_RS02745	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAL15_RS02750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAL15_RS02770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CAL15_RS02780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS02785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL15_RS02790	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS02805	COG0784	Response regulator, receiver
CAL15_RS02805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS02805	COG2205	protein histidine kinase activity
CAL15_RS02805	COG2198	Histidine kinase
CAL15_RS02815	COG0582	viral genome integration into host DNA
CAL15_RS02820	COG4974	Belongs to the 'phage' integrase family
CAL15_RS02825	COG0517	IMP dehydrogenase activity
CAL15_RS02835	COG3932	Exopolysaccharide synthesis, ExoD
CAL15_RS02850	COG2212	antiporter activity
CAL15_RS02855	COG1863	multisubunit Na H antiporter MnhE subunit
CAL15_RS02860	COG0651	ATP synthesis coupled electron transport
CAL15_RS02865	COG1006	Multisubunit Na H antiporter MnhC subunit
CAL15_RS02870	COG2111	Na H antiporter
CAL15_RS02870	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAL15_RS02875	COG0530	calcium, potassium:sodium antiporter activity
CAL15_RS02895	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL15_RS02920	COG0670	Belongs to the BI1 family
CAL15_RS02995	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAL15_RS03000	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL15_RS03005	COG0129	dihydroxy-acid dehydratase activity
CAL15_RS03010	COG0418	dihydroorotase activity
CAL15_RS03050	COG0501	Belongs to the peptidase M48B family
CAL15_RS03075	COG0583	DNA-binding transcription factor activity
CAL15_RS03080	COG0009	L-threonylcarbamoyladenylate synthase
CAL15_RS03090	COG2003	Belongs to the UPF0758 family
CAL15_RS03150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CAL15_RS03165	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CAL15_RS03320	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAL15_RS03385	COG0583	DNA-binding transcription factor activity
CAL15_RS03395	COG0583	DNA-binding transcription factor activity
CAL15_RS03405	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAL15_RS03415	COG1178	ABC-type Fe3 transport system permease component
CAL15_RS03420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL15_RS03435	COG0583	DNA-binding transcription factor activity
CAL15_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS03450	COG0028	Belongs to the TPP enzyme family
CAL15_RS03460	COG0583	DNA-binding transcription factor activity
CAL15_RS03465	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS03485	COG0477	Major facilitator Superfamily
CAL15_RS03545	COG1132	(ABC) transporter
CAL15_RS03570	COG4221	oxidoreductase activity
CAL15_RS03580	COG0583	DNA-binding transcription factor activity
CAL15_RS03605	COG4177	L-phenylalanine transmembrane transporter activity
CAL15_RS03645	COG4789	Type iii secretion
CAL15_RS03730	COG1317	bacterial-type flagellum organization
CAL15_RS03750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL15_RS03755	COG4790	Type iii secretion
CAL15_RS03760	COG4794	Type iii secretion
CAL15_RS03765	COG4791	protein targeting
CAL15_RS03770	COG4792	protein secretion
CAL15_RS03785	COG1595	DNA-templated transcription, initiation
CAL15_RS03805	COG2208	phosphoserine phosphatase activity
CAL15_RS03805	COG2770	Histidine kinase
CAL15_RS03815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAL15_RS03820	COG2172	sigma factor antagonist activity
CAL15_RS03825	COG1366	Belongs to the anti-sigma-factor antagonist family
CAL15_RS03885	COG0583	DNA-binding transcription factor activity
CAL15_RS03895	COG4772	TonB-dependent receptor
CAL15_RS03925	COG0010	Belongs to the arginase family
CAL15_RS04020	COG2203	Gaf domain
CAL15_RS04020	COG3706	GGDEF domain
CAL15_RS04020	COG5001	Diguanylate cyclase
CAL15_RS04020	COG4251	negative regulation of phosphorylation
CAL15_RS04035	COG1054	Belongs to the UPF0176 family
CAL15_RS04050	COG0489	protein tyrosine kinase activity
CAL15_RS04065	COG0717	Belongs to the dCTP deaminase family
CAL15_RS04070	COG0583	DNA-binding transcription factor activity
CAL15_RS04075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS04085	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS04115	COG2081	HI0933 family
CAL15_RS04120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL15_RS04135	COG4948	Mandelate Racemase Muconate Lactonizing
CAL15_RS04145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAL15_RS04150	COG0509	glycine decarboxylation via glycine cleavage system
CAL15_RS04155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL15_RS04155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL15_RS04170	COG4172	Belongs to the ABC transporter superfamily
CAL15_RS04175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS04180	COG0601	transmembrane transport
CAL15_RS04185	COG0747	negative chemotaxis
CAL15_RS04195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL15_RS04200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS04210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAL15_RS04220	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CAL15_RS04225	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL15_RS04230	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAL15_RS04255	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS04260	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS04265	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS04275	COG1464	Belongs to the NlpA lipoprotein family
CAL15_RS04285	COG2011	ABC-type metal ion transport system permease component
CAL15_RS04290	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAL15_RS04295	COG1464	Belongs to the NlpA lipoprotein family
CAL15_RS04310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS04315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL15_RS04320	COG0166	Belongs to the GPI family
CAL15_RS04330	COG0277	FAD linked oxidase domain protein
CAL15_RS04335	COG0745	RESPONSE REGULATOR receiver
CAL15_RS04340	COG0642	Histidine kinase
CAL15_RS04345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL15_RS04345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS04355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS04365	COG2186	Transcriptional regulator
CAL15_RS04370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS04375	COG1368	sulfuric ester hydrolase activity
CAL15_RS04380	COG1414	Transcriptional regulator
CAL15_RS04390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS04405	COG1024	Enoyl-CoA hydratase
CAL15_RS04430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL15_RS04440	COG0583	DNA-binding transcription factor activity
CAL15_RS04460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAL15_RS04470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CAL15_RS04475	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CAL15_RS04490	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CAL15_RS04505	COG3958	Transketolase
CAL15_RS04510	COG3959	Transketolase, thiamine diphosphate binding domain
CAL15_RS04515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS04525	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS04530	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS04535	COG0583	DNA-binding transcription factor activity
CAL15_RS04540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL15_RS04545	COG0012	GTP binding
CAL15_RS04560	COG2814	Major facilitator Superfamily
CAL15_RS04585	COG0604	alcohol dehydrogenase
CAL15_RS04595	COG0583	DNA-binding transcription factor activity
CAL15_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS04615	COG0583	DNA-binding transcription factor activity
CAL15_RS04620	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS04630	COG2267	carboxylic ester hydrolase activity
CAL15_RS04635	COG3622	Belongs to the hyi family
CAL15_RS04650	COG3135	benzoate transporter
CAL15_RS04655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAL15_RS04660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAL15_RS04665	COG0742	ribosomal rna small subunit methyltransferase
CAL15_RS04675	COG3025	triphosphatase activity
CAL15_RS04690	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAL15_RS04695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL15_RS04705	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CAL15_RS04715	COG0284	orotidine-5'-phosphate decarboxylase activity
CAL15_RS04720	COG1252	NADH dehydrogenase
CAL15_RS04725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CAL15_RS04730	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL15_RS04740	COG1335	isochorismatase
CAL15_RS04755	COG0459	protein refolding
CAL15_RS04760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL15_RS04775	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL15_RS04790	COG1595	DNA-templated transcription, initiation
CAL15_RS04800	COG0583	DNA-binding transcription factor activity
CAL15_RS04805	COG1764	response to oxidative stress
CAL15_RS04820	COG1335	isochorismatase
CAL15_RS04875	COG0300	oxidoreductase activity
CAL15_RS04880	COG2207	Transcriptional regulator
CAL15_RS04890	COG2985	domain, Protein
CAL15_RS04905	COG0693	protein deglycase activity
CAL15_RS04920	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS04930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS04940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL15_RS04945	COG2721	sulfolactate sulfo-lyase activity
CAL15_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS04985	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CAL15_RS05065	COG4191	Histidine kinase
CAL15_RS05070	COG4566	intracellular signal transduction
CAL15_RS05085	COG2995	paraquat-inducible protein a
CAL15_RS05090	COG3008	intermembrane lipid transfer
CAL15_RS05090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL15_RS05125	COG2202	Pas domain
CAL15_RS05125	COG3920	Histidine kinase
CAL15_RS05135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL15_RS05160	COG0596	Alpha beta hydrolase
CAL15_RS05175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAL15_RS05175	COG1793	dna ligase
CAL15_RS05180	COG1793	dna ligase
CAL15_RS05185	COG1201	RNA secondary structure unwinding
CAL15_RS05200	COG0583	DNA-binding transcription factor activity
CAL15_RS05225	COG0702	epimerase
CAL15_RS05235	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CAL15_RS05240	COG2223	nitrite transmembrane transporter activity
CAL15_RS05250	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS05255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS05260	COG2301	Belongs to the HpcH HpaI aldolase family
CAL15_RS05285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS05290	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL15_RS05295	COG2080	2 iron, 2 sulfur cluster binding
CAL15_RS05315	COG1360	Flagellar Motor Protein
CAL15_RS05335	COG0477	Major facilitator Superfamily
CAL15_RS05350	COG2814	Major facilitator Superfamily
CAL15_RS05360	COG2203	Gaf domain
CAL15_RS05360	COG3706	GGDEF domain
CAL15_RS05360	COG4251	negative regulation of phosphorylation
CAL15_RS05360	COG5001	Diguanylate cyclase
CAL15_RS05370	COG0058	SHG alpha-glucan phosphorylase activity
CAL15_RS05380	COG4191	Histidine kinase
CAL15_RS05380	COG0784	Response regulator, receiver
CAL15_RS05385	COG0456	acetyltransferase
CAL15_RS05400	COG2814	Major facilitator Superfamily
CAL15_RS05410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS05410	COG4191	Histidine kinase
CAL15_RS05415	COG5001	Diguanylate cyclase
CAL15_RS05415	COG3300	MHYT domain
CAL15_RS05420	COG2943	transferase activity, transferring hexosyl groups
CAL15_RS05440	COG2070	2-Nitropropane dioxygenase
CAL15_RS05450	COG0477	Major facilitator Superfamily
CAL15_RS05460	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS05480	COG1408	metallophosphoesterase
CAL15_RS05490	COG5002	protein histidine kinase activity
CAL15_RS05490	COG2198	Histidine kinase
CAL15_RS05490	COG0784	Response regulator, receiver
CAL15_RS05510	COG0411	ABC transporter
CAL15_RS05530	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAL15_RS05540	COG1121	(ABC) transporter
CAL15_RS05550	COG0405	Gamma-glutamyltransferase
CAL15_RS05565	COG1937	Protein conserved in bacteria
CAL15_RS05575	COG1846	Transcriptional regulator
CAL15_RS05580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL15_RS05585	COG0642	Histidine kinase
CAL15_RS05610	COG2066	Belongs to the glutaminase family
CAL15_RS05645	COG4942	peptidase
CAL15_RS05660	COG1666	GTP binding
CAL15_RS05665	COG0583	DNA-binding transcription factor activity
CAL15_RS05685	COG3657	addiction module killer protein
CAL15_RS05690	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAL15_RS05705	COG0405	Gamma-glutamyltransferase
CAL15_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS05805	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAL15_RS05810	COG3383	formate dehydrogenase (NAD+) activity
CAL15_RS05830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAL15_RS05835	COG0303	'Molybdopterin
CAL15_RS05840	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL15_RS05845	COG0314	molybdopterin synthase activity
CAL15_RS05855	COG0315	cyclic pyranopterin monophosphate synthase activity
CAL15_RS05860	COG0412	Dienelactone hydrolase
CAL15_RS05865	COG0678	peroxiredoxin activity
CAL15_RS05880	COG0697	spore germination
CAL15_RS05885	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAL15_RS05890	COG0737	Belongs to the 5'-nucleotidase family
CAL15_RS05910	COG0667	Aldo Keto reductase
CAL15_RS05915	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CAL15_RS05920	COG4535	Mg2 and Co2 transporter CorC
CAL15_RS05925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAL15_RS05930	COG1702	phosphate starvation-inducible protein PhoH
CAL15_RS05935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL15_RS05940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL15_RS05945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL15_RS05950	COG1862	Preprotein translocase
CAL15_RS05965	COG0343	queuine tRNA-ribosyltransferase activity
CAL15_RS05970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CAL15_RS05985	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS05990	COG2027	D-alanyl-D-alanine carboxypeptidase
CAL15_RS05995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAL15_RS06000	COG1648	precorrin-2 dehydrogenase activity
CAL15_RS06000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAL15_RS06005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL15_RS06010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS06015	COG1116	anion transmembrane transporter activity
CAL15_RS06020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL15_RS06025	COG0243	molybdopterin cofactor binding
CAL15_RS06030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS06040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL15_RS06065	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CAL15_RS06070	COG0741	lytic transglycosylase activity
CAL15_RS06075	COG0436	Aminotransferase
CAL15_RS06085	COG0280	phosphate acetyltransferase
CAL15_RS06085	COG0281	malic enzyme
CAL15_RS06095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL15_RS06100	COG0714	Associated with various cellular activities
CAL15_RS06110	COG2304	oxidoreductase activity
CAL15_RS06195	COG0840	transmembrane signaling receptor activity
CAL15_RS06225	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS06245	COG0235	Class ii aldolase
CAL15_RS06250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS06250	COG2010	Cytochrome c
CAL15_RS06255	COG2010	Cytochrome c
CAL15_RS06255	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS06260	COG2080	2 iron, 2 sulfur cluster binding
CAL15_RS06275	COG0154	amidase activity
CAL15_RS06280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL15_RS06285	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS06290	COG0235	Class ii aldolase
CAL15_RS06300	COG1561	YicC-like family, N-terminal region
CAL15_RS06320	COG2079	MmgE PrpD family protein
CAL15_RS06325	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS06335	COG0840	transmembrane signaling receptor activity
CAL15_RS06340	COG2200	EAL domain
CAL15_RS06345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAL15_RS06350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAL15_RS06355	COG0174	glutamine synthetase
CAL15_RS06365	COG2204	response regulator
CAL15_RS06405	COG0583	DNA-binding transcription factor activity
CAL15_RS06410	COG1741	Belongs to the pirin family
CAL15_RS06415	COG1741	Belongs to the pirin family
CAL15_RS06420	COG3842	ATPase activity
CAL15_RS06430	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL15_RS06475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAL15_RS06480	COG0583	DNA-binding transcription factor activity
CAL15_RS06485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS06495	COG0783	Belongs to the Dps family
CAL15_RS06500	COG0300	oxidoreductase activity
CAL15_RS06550	COG2089	acid synthase
CAL15_RS06555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL15_RS06565	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
CAL15_RS06570	COG1086	Polysaccharide biosynthesis protein
CAL15_RS06575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAL15_RS06580	COG1083	cytidylyl-transferase
CAL15_RS06585	COG0156	8-amino-7-oxononanoate synthase activity
CAL15_RS06590	COG0604	alcohol dehydrogenase
CAL15_RS06590	COG3321	synthase
CAL15_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS06610	COG3971	2-oxopent-4-enoate hydratase activity
CAL15_RS06630	COG3842	ATPase activity
CAL15_RS06635	COG0395	ABC-type sugar transport system, permease component
CAL15_RS06640	COG1175	transmembrane transport
CAL15_RS06645	COG1653	transport
CAL15_RS06660	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CAL15_RS06670	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL15_RS06680	COG0411	ABC transporter
CAL15_RS06690	COG1794	racemase activity, acting on amino acids and derivatives
CAL15_RS06695	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL15_RS06705	COG0583	DNA-binding transcription factor activity
CAL15_RS06715	COG0625	glutathione transferase activity
CAL15_RS06720	COG0697	spore germination
CAL15_RS06725	COG2363	Small membrane protein
CAL15_RS06730	COG1464	Belongs to the NlpA lipoprotein family
CAL15_RS06735	COG0688	phosphatidylethanolamine metabolic process
CAL15_RS06745	COG3416	Protein conserved in bacteria
CAL15_RS06750	COG0861	Integral membrane protein TerC family
CAL15_RS06760	COG3685	Protein conserved in bacteria
CAL15_RS06770	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL15_RS06775	COG2204	response regulator
CAL15_RS06785	COG0028	Belongs to the TPP enzyme family
CAL15_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS06835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS06840	COG3842	ATPase activity
CAL15_RS06845	COG0395	ABC-type sugar transport system, permease component
CAL15_RS06850	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS06860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAL15_RS06880	COG1414	Transcriptional regulator
CAL15_RS06895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL15_RS06905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL15_RS06910	COG0366	Alpha amylase catalytic
CAL15_RS06915	COG0366	Alpha amylase catalytic
CAL15_RS06920	COG0297	glycogen (starch) synthase activity
CAL15_RS06935	COG5265	(ABC) transporter
CAL15_RS06940	COG0297	glycogen (starch) synthase activity
CAL15_RS06945	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS06950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL15_RS06955	COG0859	PFAM glycosyl transferase family 9
CAL15_RS06960	COG2192	nodulation
CAL15_RS06980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL15_RS07000	COG1546	Belongs to the CinA family
CAL15_RS07000	COG1058	Belongs to the CinA family
CAL15_RS07015	COG0392	lysyltransferase activity
CAL15_RS07020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL15_RS07025	COG3568	Endonuclease Exonuclease Phosphatase
CAL15_RS07035	COG3850	Histidine kinase
CAL15_RS07035	COG3437	response regulator, receiver
CAL15_RS07035	COG4999	Histidine kinase
CAL15_RS07035	COG2205	protein histidine kinase activity
CAL15_RS07040	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL15_RS07045	COG5002	protein histidine kinase activity
CAL15_RS07085	COG0028	Belongs to the TPP enzyme family
CAL15_RS07095	COG1414	Transcriptional regulator
CAL15_RS07100	COG3706	GGDEF domain
CAL15_RS07125	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS07160	COG1802	Transcriptional regulator
CAL15_RS07170	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS07175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL15_RS07180	COG3842	ATPase activity
CAL15_RS07195	COG0395	ABC-type sugar transport system, permease component
CAL15_RS07220	COG0583	DNA-binding transcription factor activity
CAL15_RS07225	COG1063	alcohol dehydrogenase
CAL15_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS07245	COG3064	Membrane
CAL15_RS07255	COG0737	Belongs to the 5'-nucleotidase family
CAL15_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS07270	COG4977	sequence-specific DNA binding
CAL15_RS07275	COG0431	NADPH-dependent FMN reductase
CAL15_RS07285	COG0798	PFAM Bile acid sodium symporter
CAL15_RS07295	COG0640	Transcriptional regulator
CAL15_RS07300	COG1802	Transcriptional regulator
CAL15_RS07305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS07310	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS07320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS07345	COG0024	Methionine aminopeptidase
CAL15_RS07370	COG0114	fumarate hydratase activity
CAL15_RS07380	COG0235	Class ii aldolase
CAL15_RS07410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS07415	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS07455	COG1393	Belongs to the ArsC family
CAL15_RS07480	COG0386	Belongs to the glutathione peroxidase family
CAL15_RS07485	COG1522	sequence-specific DNA binding
CAL15_RS07495	COG0625	glutathione transferase activity
CAL15_RS07510	COG0095	Lipoate-protein ligase
CAL15_RS07520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAL15_RS07530	COG0084	hydrolase, TatD family'
CAL15_RS07535	COG0470	DNA polymerase III
CAL15_RS07540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CAL15_RS07545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAL15_RS07570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CAL15_RS07575	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS07580	COG2914	Belongs to the UPF0125 (RnfH) family
CAL15_RS07590	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CAL15_RS07600	COG0330	HflC and HflK could
CAL15_RS07610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL15_RS07610	COG0519	Catalyzes the synthesis of GMP from XMP
CAL15_RS07625	COG2084	Dehydrogenase
CAL15_RS07640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CAL15_RS07645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL15_RS07650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAL15_RS07660	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL15_RS07665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAL15_RS07670	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL15_RS07675	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CAL15_RS07680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL15_RS07685	COG0750	zinc metalloprotease
CAL15_RS07690	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAL15_RS07695	COG0575	Belongs to the CDS family
CAL15_RS07700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAL15_RS07705	COG0233	cytoplasmic translational termination
CAL15_RS07710	COG0528	UMP kinase activity
CAL15_RS07715	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAL15_RS07720	COG0052	Belongs to the universal ribosomal protein uS2 family
CAL15_RS07725	COG0024	Methionine aminopeptidase
CAL15_RS07730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CAL15_RS07740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAL15_RS07760	COG0285	dihydrofolate synthase activity
CAL15_RS07770	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAL15_RS07775	COG1516	flagellar protein fliS
CAL15_RS07790	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAL15_RS07800	COG1677	Flagellar hook-basal body complex protein FliE
CAL15_RS07810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL15_RS07815	COG1317	bacterial-type flagellum organization
CAL15_RS07820	COG1157	protein secretion by the type III secretion system
CAL15_RS07835	COG1580	Controls the rotational direction of flagella during chemotaxis
CAL15_RS07845	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL15_RS07860	COG1987	bacterial-type flagellum assembly
CAL15_RS07870	COG0840	transmembrane signaling receptor activity
CAL15_RS07880	COG0840	transmembrane signaling receptor activity
CAL15_RS07885	COG0840	transmembrane signaling receptor activity
CAL15_RS07895	COG1256	bacterial-type flagellum assembly
CAL15_RS07920	COG4787	bacterial-type flagellum-dependent cell motility
CAL15_RS07935	COG1558	bacterial-type flagellum-dependent cell motility
CAL15_RS07940	COG1815	bacterial-type flagellum-dependent cell motility
CAL15_RS07975	COG3706	GGDEF domain
CAL15_RS07980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CAL15_RS07985	COG0745	RESPONSE REGULATOR receiver
CAL15_RS07990	COG2201	protein-glutamate methylesterase activity
CAL15_RS07995	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL15_RS08000	COG0840	transmembrane signaling receptor activity
CAL15_RS08005	COG0835	chemotaxis
CAL15_RS08010	COG0643	Histidine kinase
CAL15_RS08010	COG2198	Histidine kinase
CAL15_RS08015	COG0745	RESPONSE REGULATOR receiver
CAL15_RS08040	COG1191	sigma factor activity
CAL15_RS08055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CAL15_RS08100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL15_RS08105	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL15_RS08110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CAL15_RS08120	COG4566	intracellular signal transduction
CAL15_RS08125	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAL15_RS08130	COG0339	signal peptide processing
CAL15_RS08135	COG1999	signal sequence binding
CAL15_RS08165	COG3161	chorismate lyase activity
CAL15_RS08180	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS08185	COG4172	Belongs to the ABC transporter superfamily
CAL15_RS08190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS08195	COG0601	transmembrane transport
CAL15_RS08290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CAL15_RS08290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CAL15_RS08295	COG0165	Argininosuccinate lyase
CAL15_RS08300	COG0778	Nitroreductase
CAL15_RS08305	COG0789	Transcriptional regulator
CAL15_RS08320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS08325	COG0765	amino acid transport
CAL15_RS08330	COG1126	abc transporter atp-binding protein
CAL15_RS08340	COG0583	DNA-binding transcription factor activity
CAL15_RS08350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL15_RS08365	COG3706	GGDEF domain
CAL15_RS08370	COG2203	Gaf domain
CAL15_RS08370	COG2199	diguanylate cyclase activity
CAL15_RS08390	COG2988	succinylglutamate desuccinylase activity
CAL15_RS08400	COG0583	DNA-binding transcription factor activity
CAL15_RS08405	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAL15_RS08415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CAL15_RS08420	COG2188	Transcriptional regulator
CAL15_RS08425	COG3624	Phosphonate C-P lyase system protein PhnG
CAL15_RS08430	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CAL15_RS08435	COG3626	phosphonate metabolism
CAL15_RS08440	COG3627	carbon phosphorus lyase activity
CAL15_RS08445	COG4107	phosphonate C-P lyase system protein PhnK
CAL15_RS08450	COG4778	phosphonate C-P lyase system protein PhnL
CAL15_RS08455	COG3454	Phosphonate metabolism
CAL15_RS08460	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CAL15_RS08465	COG0501	Belongs to the peptidase M48B family
CAL15_RS08470	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS08475	COG0129	dihydroxy-acid dehydratase activity
CAL15_RS08480	COG0583	DNA-binding transcription factor activity
CAL15_RS08485	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS08490	COG3246	L-lysine catabolic process to acetate
CAL15_RS08500	COG0583	DNA-binding transcription factor activity
CAL15_RS08505	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS08530	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CAL15_RS08575	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS08580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL15_RS08600	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CAL15_RS08605	COG2207	Transcriptional regulator
CAL15_RS08650	COG4691	Plasmid stability protein
CAL15_RS08685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL15_RS08745	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CAL15_RS08755	COG1418	mRNA catabolic process
CAL15_RS08760	COG3795	YCII-related domain
CAL15_RS08775	COG4941	Belongs to the sigma-70 factor family
CAL15_RS08780	COG0183	Belongs to the thiolase family
CAL15_RS08790	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CAL15_RS08795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS08800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL15_RS08815	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS08830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS08855	COG3585	molybdate ion transport
CAL15_RS08865	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAL15_RS08870	COG0431	NADPH-dependent FMN reductase
CAL15_RS08885	COG5265	(ABC) transporter
CAL15_RS08895	COG0387	Pfam Sodium calcium exchanger
CAL15_RS08905	COG4191	Histidine kinase
CAL15_RS08905	COG0784	Response regulator, receiver
CAL15_RS08915	COG2910	NAD(P)H-binding
CAL15_RS08920	COG0583	DNA-binding transcription factor activity
CAL15_RS08945	COG1309	transcriptional regulator
CAL15_RS08955	COG0596	Alpha beta hydrolase
CAL15_RS08965	COG0583	DNA-binding transcription factor activity
CAL15_RS08990	COG1846	Transcriptional regulator
CAL15_RS09015	COG1733	regulation of RNA biosynthetic process
CAL15_RS09020	COG0583	DNA-binding transcription factor activity
CAL15_RS09030	COG1335	isochorismatase
CAL15_RS09040	COG0667	Aldo Keto reductase
CAL15_RS09060	COG0667	Aldo Keto reductase
CAL15_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS09080	COG0519	Catalyzes the synthesis of GMP from XMP
CAL15_RS09080	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL15_RS09105	COG3842	ATPase activity
CAL15_RS09110	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS09115	COG1177	transmembrane transport
CAL15_RS09125	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAL15_RS09130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS09140	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS09170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAL15_RS09170	COG0047	phosphoribosylformylglycinamidine synthase activity
CAL15_RS09180	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL15_RS09180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS09185	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS09195	COG0596	Alpha beta hydrolase
CAL15_RS09205	COG0613	PHP domain protein
CAL15_RS09240	COG0583	DNA-binding transcription factor activity
CAL15_RS09260	COG0640	Transcriptional regulator
CAL15_RS09280	COG4604	ABC transporter, ATP-binding protein
CAL15_RS09285	COG4605	iron ion homeostasis
CAL15_RS09290	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAL15_RS09295	COG4607	ABC-type enterochelin transport system periplasmic component
CAL15_RS09300	COG4771	TonB-dependent receptor
CAL15_RS09305	COG0745	RESPONSE REGULATOR receiver
CAL15_RS09310	COG2205	protein histidine kinase activity
CAL15_RS09315	COG0084	hydrolase, TatD family'
CAL15_RS09320	COG1136	(ABC) transporter
CAL15_RS09345	COG2271	Major facilitator Superfamily
CAL15_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS09360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAL15_RS09375	COG1022	Amp-dependent synthetase and ligase
CAL15_RS09410	COG1803	Methylglyoxal synthase
CAL15_RS09425	COG0633	Ferredoxin
CAL15_RS09430	COG0443	Heat shock 70 kDa protein
CAL15_RS09440	COG0316	Belongs to the HesB IscA family
CAL15_RS09445	COG0822	iron-sulfur transferase activity
CAL15_RS09450	COG1104	cysteine desulfurase activity
CAL15_RS09460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAL15_RS09465	COG0556	nucleotide-excision repair
CAL15_RS09475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CAL15_RS09485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAL15_RS09495	COG0740	serine-type endopeptidase activity
CAL15_RS09500	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAL15_RS09510	COG1278	Cold shock
CAL15_RS09515	COG1278	Cold shock
CAL15_RS09530	COG3706	GGDEF domain
CAL15_RS09530	COG5001	Diguanylate cyclase
CAL15_RS09530	COG4251	negative regulation of phosphorylation
CAL15_RS09530	COG2203	Gaf domain
CAL15_RS09540	COG0436	Aminotransferase
CAL15_RS09545	COG2171	N-acyltransferase activity
CAL15_RS09555	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL15_RS09560	COG0488	(ABC) transporter
CAL15_RS09565	COG0210	DNA helicase
CAL15_RS09580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL15_RS09580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL15_RS09585	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAL15_RS09590	COG0196	riboflavin kinase activity
CAL15_RS09595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAL15_RS09600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAL15_RS09605	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAL15_RS09615	COG1522	sequence-specific DNA binding
CAL15_RS09635	COG0756	dUTP diphosphatase activity
CAL15_RS09640	COG1902	pentaerythritol trinitrate reductase activity
CAL15_RS09645	COG1126	abc transporter atp-binding protein
CAL15_RS09650	COG0765	amino acid transport
CAL15_RS09655	COG0765	amino acid transport
CAL15_RS09660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS09670	COG2423	ornithine cyclodeaminase activity
CAL15_RS09675	COG1764	response to oxidative stress
CAL15_RS09680	COG1914	H( )-stimulated, divalent metal cation uptake system
CAL15_RS09690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAL15_RS09695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAL15_RS09710	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CAL15_RS09715	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAL15_RS09720	COG2197	response regulator
CAL15_RS09740	COG0135	phosphoribosylanthranilate isomerase activity
CAL15_RS09745	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL15_RS09750	COG0101	tRNA pseudouridine synthase activity
CAL15_RS09760	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAL15_RS09770	COG0066	3-isopropylmalate dehydratase activity
CAL15_RS09780	COG4783	chaperone-mediated protein folding
CAL15_RS09785	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAL15_RS09795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CAL15_RS09805	COG1295	ribonuclease BN
CAL15_RS09815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAL15_RS09845	COG4964	Belongs to the GSP D family
CAL15_RS09875	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAL15_RS09880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL15_RS09895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CAL15_RS09915	COG0181	hydroxymethylbilane synthase activity
CAL15_RS09920	COG0861	Integral membrane protein TerC family
CAL15_RS09925	COG0861	Integral membrane protein TerC family
CAL15_RS09930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CAL15_RS09935	COG0045	succinate-CoA ligase (ADP-forming) activity
CAL15_RS09955	COG2137	regulation of response to DNA damage stimulus
CAL15_RS09960	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAL15_RS09995	COG0540	Belongs to the ATCase OTCase family
CAL15_RS10030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS10050	COG0784	Response regulator, receiver
CAL15_RS10050	COG4191	Histidine kinase
CAL15_RS10070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAL15_RS10080	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CAL15_RS10085	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CAL15_RS10090	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAL15_RS10095	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CAL15_RS10100	COG0330	HflC and HflK could
CAL15_RS10105	COG0330	HflC and HflK could
CAL15_RS10110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAL15_RS10115	COG1923	regulation of RNA biosynthetic process
CAL15_RS10125	COG1160	GTP binding
CAL15_RS10130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL15_RS10155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAL15_RS10160	COG0105	UTP biosynthetic process
CAL15_RS10165	COG0525	valine-tRNA ligase activity
CAL15_RS10200	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS10215	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL15_RS10235	COG1139	Iron-sulfur cluster binding protein
CAL15_RS10240	COG0247	lactate metabolic process
CAL15_RS10245	COG2186	Transcriptional regulator
CAL15_RS10250	COG3713	MltA-interacting MipA family protein
CAL15_RS10260	COG0642	Histidine kinase
CAL15_RS10265	COG0336	Belongs to the RNA methyltransferase TrmD family
CAL15_RS10275	COG0228	four-way junction DNA binding
CAL15_RS10280	COG0425	Belongs to the sulfur carrier protein TusA family
CAL15_RS10285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CAL15_RS10335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS10350	COG0633	Ferredoxin
CAL15_RS10350	COG3217	Mosc domain protein beta barrel domain protein
CAL15_RS10360	COG5285	phytanoyl-CoA dioxygenase
CAL15_RS10365	COG0662	Cupin 2, conserved barrel domain protein
CAL15_RS10375	COG0456	acetyltransferase
CAL15_RS10400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CAL15_RS10410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CAL15_RS10415	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAL15_RS10420	COG1760	l-serine dehydratase
CAL15_RS10460	COG1217	gtp-binding protein TYPA
CAL15_RS10465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAL15_RS10470	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAL15_RS10475	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAL15_RS10480	COG2251	uridine kinase activity
CAL15_RS10480	COG0195	Participates in both transcription termination and antitermination
CAL15_RS10485	COG0779	Required for maturation of 30S ribosomal subunits
CAL15_RS10490	COG1187	pseudouridine synthase activity
CAL15_RS10495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAL15_RS10505	COG0523	cobalamin synthesis protein
CAL15_RS10520	COG0625	glutathione transferase activity
CAL15_RS10525	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAL15_RS10530	COG1047	Peptidyl-prolyl cis-trans
CAL15_RS10535	COG2003	Belongs to the UPF0758 family
CAL15_RS10550	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS10555	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CAL15_RS10560	COG3844	kynureninase activity
CAL15_RS10565	COG3483	tryptophan 2,3-dioxygenase activity
CAL15_RS10580	COG0534	Mate efflux family protein
CAL15_RS10600	COG2304	oxidoreductase activity
CAL15_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS10620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAL15_RS10625	COG1562	ergosterol biosynthetic process
CAL15_RS10640	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAL15_RS10655	COG0542	response to heat
CAL15_RS10690	COG0494	nUDIX hydrolase
CAL15_RS10710	COG0745	RESPONSE REGULATOR receiver
CAL15_RS10725	COG2814	Major facilitator Superfamily
CAL15_RS10740	COG0583	DNA-binding transcription factor activity
CAL15_RS10745	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CAL15_RS10765	COG2900	Belongs to the SlyX family
CAL15_RS10780	COG0842	Transport permease protein
CAL15_RS10785	COG1131	(ABC) transporter
CAL15_RS10790	COG1764	response to oxidative stress
CAL15_RS10795	COG1846	Transcriptional regulator
CAL15_RS10805	COG2224	Isocitrate lyase
CAL15_RS10810	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL15_RS10810	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL15_RS10820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAL15_RS10835	COG0736	holo-[acyl-carrier-protein] synthase activity
CAL15_RS10845	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CAL15_RS10855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL15_RS10860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL15_RS10900	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS10905	COG1024	Enoyl-CoA hydratase
CAL15_RS10915	COG1802	Transcriptional regulator
CAL15_RS10925	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS10930	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS10945	COG1024	Enoyl-CoA hydratase
CAL15_RS10955	COG0183	Belongs to the thiolase family
CAL15_RS10960	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS10965	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS10975	COG0583	DNA-binding transcription factor activity
CAL15_RS11000	COG4176	ABC-type proline glycine betaine transport system permease component
CAL15_RS11010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL15_RS11015	COG2814	Major facilitator Superfamily
CAL15_RS11020	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CAL15_RS11025	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAL15_RS11045	COG1846	Transcriptional regulator
CAL15_RS11050	COG2814	Major facilitator Superfamily
CAL15_RS11055	COG0495	leucyl-tRNA aminoacylation
CAL15_RS11065	COG1466	dna polymerase III delta subunit
CAL15_RS11070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAL15_RS11090	COG0625	glutathione transferase activity
CAL15_RS11130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS11135	COG1132	(ABC) transporter
CAL15_RS11155	COG0726	polysaccharide deacetylase
CAL15_RS11175	COG0405	Gamma-glutamyltransferase
CAL15_RS11180	COG0583	DNA-binding transcription factor activity
CAL15_RS11190	COG1643	Atp-dependent helicase
CAL15_RS11195	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL15_RS11195	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAL15_RS11200	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CAL15_RS11210	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS11230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAL15_RS11235	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS11240	COG3384	dioxygenase
CAL15_RS11255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAL15_RS11275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL15_RS11280	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS11285	COG1024	Enoyl-CoA hydratase
CAL15_RS11315	COG4172	Belongs to the ABC transporter superfamily
CAL15_RS11320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS11325	COG0601	transmembrane transport
CAL15_RS11340	COG0598	Magnesium transport protein CorA
CAL15_RS11375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAL15_RS11380	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS11385	COG3707	response regulator
CAL15_RS11395	COG0515	serine threonine protein kinase
CAL15_RS11395	COG2815	serine threonine protein kinase
CAL15_RS11400	COG2116	formate transmembrane transporter activity
CAL15_RS11405	COG2146	nitrite reductase [NAD(P)H] activity
CAL15_RS11405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL15_RS11410	COG2146	nitrite reductase [NAD(P)H] activity
CAL15_RS11410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL15_RS11430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAL15_RS11435	COG1045	serine acetyltransferase
CAL15_RS11445	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS11450	COG0183	Belongs to the thiolase family
CAL15_RS11455	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS11455	COG1024	Enoyl-CoA hydratase
CAL15_RS11460	COG2067	long-chain fatty acid transport protein
CAL15_RS11465	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS11465	COG1024	Enoyl-CoA hydratase
CAL15_RS11470	COG0183	Belongs to the thiolase family
CAL15_RS11475	COG2010	Cytochrome c
CAL15_RS11475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS11480	COG1335	isochorismatase
CAL15_RS11485	COG2309	aminopeptidase activity
CAL15_RS11490	COG0596	Alpha beta hydrolase
CAL15_RS11495	COG3473	Maleate cis-trans isomerase
CAL15_RS11500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL15_RS11505	COG2080	2 iron, 2 sulfur cluster binding
CAL15_RS11510	COG2010	Cytochrome c
CAL15_RS11510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS11535	COG1846	Transcriptional regulator
CAL15_RS11540	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS11545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS11555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL15_RS11600	COG1104	cysteine desulfurase activity
CAL15_RS11605	COG2223	nitrite transmembrane transporter activity
CAL15_RS11610	COG4977	sequence-specific DNA binding
CAL15_RS11610	COG1917	Cupin 2, conserved barrel domain protein
CAL15_RS11640	COG1902	pentaerythritol trinitrate reductase activity
CAL15_RS11645	COG0640	Transcriptional regulator
CAL15_RS11660	COG0667	Aldo Keto reductase
CAL15_RS11675	COG0459	protein refolding
CAL15_RS11680	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL15_RS11695	COG0537	adenosine 5'-monophosphoramidase activity
CAL15_RS11700	COG3706	GGDEF domain
CAL15_RS11700	COG5001	Diguanylate cyclase
CAL15_RS11700	COG2203	Gaf domain
CAL15_RS11700	COG4251	negative regulation of phosphorylation
CAL15_RS11705	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS11715	COG2217	Heavy metal translocating P-type atpase
CAL15_RS11720	COG3278	Belongs to the heme-copper respiratory oxidase family
CAL15_RS11755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAL15_RS11760	COG0859	PFAM glycosyl transferase family 9
CAL15_RS11780	COG0527	aspartate kinase activity
CAL15_RS11790	COG0037	tRNA processing
CAL15_RS11795	COG0825	malonyl-CoA metabolic process
CAL15_RS11805	COG0215	cysteine-tRNA ligase activity
CAL15_RS11815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAL15_RS11820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL15_RS11830	COG1253	flavin adenine dinucleotide binding
CAL15_RS11835	COG0483	inositol monophosphate 1-phosphatase activity
CAL15_RS11855	COG0668	transmembrane transport
CAL15_RS11895	COG3360	Dodecin
CAL15_RS11905	COG2831	hemolysin activation secretion protein
CAL15_RS11925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CAL15_RS11930	COG2850	peptidyl-arginine hydroxylation
CAL15_RS11940	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CAL15_RS11945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS11950	COG1994	Peptidase M50
CAL15_RS11955	COG0009	L-threonylcarbamoyladenylate synthase
CAL15_RS11960	COG2321	neutral zinc metallopeptidase
CAL15_RS11995	COG1131	(ABC) transporter
CAL15_RS12025	COG1129	ABC transporter
CAL15_RS12060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS12065	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CAL15_RS12090	COG2205	protein histidine kinase activity
CAL15_RS12125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL15_RS12140	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12175	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CAL15_RS12225	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL15_RS12230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS12250	COG0683	leucine binding
CAL15_RS12280	COG0165	Argininosuccinate lyase
CAL15_RS12285	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CAL15_RS12285	COG0493	'glutamate synthase
CAL15_RS12315	COG2197	response regulator
CAL15_RS12320	COG0297	glycogen (starch) synthase activity
CAL15_RS12325	COG0110	maltose O-acetyltransferase activity
CAL15_RS12335	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS12355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL15_RS12370	COG1051	belongs to the nudix hydrolase family
CAL15_RS12380	COG1596	polysaccharide export
CAL15_RS12385	COG3206	protein involved in exopolysaccharide biosynthesis
CAL15_RS12385	COG0489	protein tyrosine kinase activity
CAL15_RS12400	COG2197	response regulator
CAL15_RS12410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL15_RS12415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS12420	COG1116	anion transmembrane transporter activity
CAL15_RS12425	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CAL15_RS12445	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12455	COG0583	DNA-binding transcription factor activity
CAL15_RS12480	COG0444	Belongs to the ABC transporter superfamily
CAL15_RS12485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS12490	COG0601	transmembrane transport
CAL15_RS12495	COG0747	negative chemotaxis
CAL15_RS12500	COG1335	isochorismatase
CAL15_RS12505	COG2309	aminopeptidase activity
CAL15_RS12510	COG0596	Alpha beta hydrolase
CAL15_RS12515	COG3473	Maleate cis-trans isomerase
CAL15_RS12535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS12565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL15_RS12570	COG2146	nitrite reductase [NAD(P)H] activity
CAL15_RS12575	COG0446	pyridine nucleotide-disulphide oxidoreductase
CAL15_RS12605	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12625	COG0583	DNA-binding transcription factor activity
CAL15_RS12635	COG0028	Belongs to the TPP enzyme family
CAL15_RS12645	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12650	COG1414	Transcriptional regulator
CAL15_RS12655	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS12670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL15_RS12675	COG2188	Transcriptional regulator
CAL15_RS12685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL15_RS12695	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12705	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12710	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS12715	COG4302	ethanolamine ammonia-lyase activity
CAL15_RS12720	COG4303	Ethanolamine ammonia lyase large subunit
CAL15_RS12730	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CAL15_RS12770	COG2084	Dehydrogenase
CAL15_RS12780	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12805	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL15_RS12820	COG3119	arylsulfatase activity
CAL15_RS12825	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS12830	COG1809	phosphosulfolactate synthase activity
CAL15_RS12850	COG0129	dihydroxy-acid dehydratase activity
CAL15_RS12860	COG4214	carbohydrate transport
CAL15_RS12885	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS12915	COG3246	L-lysine catabolic process to acetate
CAL15_RS12920	COG2354	Protein conserved in bacteria
CAL15_RS12940	COG0683	leucine binding
CAL15_RS12980	COG1115	amino acid carrier protein
CAL15_RS12995	COG3713	MltA-interacting MipA family protein
CAL15_RS13000	COG0745	RESPONSE REGULATOR receiver
CAL15_RS13005	COG0642	Histidine kinase
CAL15_RS13035	COG0693	protein deglycase activity
CAL15_RS13050	COG1230	cation diffusion facilitator family transporter
CAL15_RS13060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL15_RS13065	COG0463	Glycosyl transferase, family 2
CAL15_RS13090	COG5002	protein histidine kinase activity
CAL15_RS13100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS13125	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS13140	COG0587	DNA-directed DNA polymerase activity
CAL15_RS13155	COG5377	YqaJ viral recombinase family
CAL15_RS13225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL15_RS13255	COG0811	peptide transport
CAL15_RS13260	COG2831	hemolysin activation secretion protein
CAL15_RS13300	COG1272	protein, Hemolysin III
CAL15_RS13310	COG1737	Transcriptional regulator
CAL15_RS13315	COG0647	UMP catabolic process
CAL15_RS13325	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CAL15_RS13350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAL15_RS13375	COG0248	Ppx GppA phosphatase
CAL15_RS13385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAL15_RS13395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL15_RS13400	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CAL15_RS13405	COG1534	Rna-binding protein
CAL15_RS13410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAL15_RS13415	COG2233	PERMEase
CAL15_RS13425	COG0406	alpha-ribazole phosphatase activity
CAL15_RS13430	COG4221	oxidoreductase activity
CAL15_RS13440	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAL15_RS13445	COG0505	Belongs to the CarA family
CAL15_RS13450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAL15_RS13465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS13480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL15_RS13490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS13500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL15_RS13505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAL15_RS13535	COG2271	Major facilitator Superfamily
CAL15_RS13550	COG1686	Belongs to the peptidase S11 family
CAL15_RS13565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL15_RS13570	COG4974	Belongs to the 'phage' integrase family
CAL15_RS13575	COG0583	DNA-binding transcription factor activity
CAL15_RS13580	COG0028	Belongs to the TPP enzyme family
CAL15_RS13595	COG0028	Belongs to the TPP enzyme family
CAL15_RS13600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS13605	COG1126	abc transporter atp-binding protein
CAL15_RS13610	COG0765	amino acid transport
CAL15_RS13625	COG1414	Transcriptional regulator
CAL15_RS13630	COG0009	L-threonylcarbamoyladenylate synthase
CAL15_RS13635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CAL15_RS13640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CAL15_RS13650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAL15_RS13660	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CAL15_RS13680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAL15_RS13690	COG0739	heme binding
CAL15_RS13700	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL15_RS13740	COG0625	glutathione transferase activity
CAL15_RS13745	COG3706	GGDEF domain
CAL15_RS13750	COG3437	response regulator, receiver
CAL15_RS13755	COG2198	Histidine kinase
CAL15_RS13755	COG2205	protein histidine kinase activity
CAL15_RS13755	COG0784	Response regulator, receiver
CAL15_RS13770	COG0859	PFAM glycosyl transferase family 9
CAL15_RS13775	COG0126	phosphoglycerate kinase activity
CAL15_RS13780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAL15_RS13785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAL15_RS13790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAL15_RS13795	COG2732	(Barnase) inhibitor
CAL15_RS13805	COG0281	malic enzyme
CAL15_RS13805	COG0280	phosphate acetyltransferase
CAL15_RS13810	COG0583	DNA-binding transcription factor activity
CAL15_RS13825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAL15_RS13830	COG0791	NLP P60 protein
CAL15_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS13840	COG0194	GDP metabolic process
CAL15_RS13845	COG1758	RNA polymerase activity
CAL15_RS13850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL15_RS13855	COG1126	abc transporter atp-binding protein
CAL15_RS13860	COG0765	amino acid transport
CAL15_RS13865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS13905	COG0583	DNA-binding transcription factor activity
CAL15_RS13930	COG4336	lyase activity
CAL15_RS13945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS13970	COG4181	ATPase activity
CAL15_RS13980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL15_RS13985	COG0584	glycerophosphoryl diester phosphodiesterase
CAL15_RS13990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CAL15_RS14010	COG0678	peroxiredoxin activity
CAL15_RS14010	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAL15_RS14020	COG2217	Heavy metal translocating P-type atpase
CAL15_RS14025	COG0789	Transcriptional regulator
CAL15_RS14035	COG2832	Protein of unknown function (DUF454)
CAL15_RS14040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAL15_RS14075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL15_RS14085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CAL15_RS14090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAL15_RS14095	COG2252	PERMEase
CAL15_RS14100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAL15_RS14105	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL15_RS14120	COG0573	inorganic phosphate transmembrane transporter activity
CAL15_RS14135	COG0488	(ABC) transporter
CAL15_RS14140	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL15_RS14150	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS14155	COG1024	Enoyl-CoA hydratase
CAL15_RS14160	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAL15_RS14165	COG0590	tRNA wobble adenosine to inosine editing
CAL15_RS14185	COG2212	antiporter activity
CAL15_RS14195	COG0651	ATP synthesis coupled electron transport
CAL15_RS14200	COG1006	Multisubunit Na H antiporter MnhC subunit
CAL15_RS14205	COG2111	Na H antiporter
CAL15_RS14205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CAL15_RS14220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS14235	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAL15_RS14245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL15_RS14260	COG0602	queuosine metabolic process
CAL15_RS14265	COG0720	synthase
CAL15_RS14300	COG0400	carboxylic ester hydrolase activity
CAL15_RS14320	COG0587	DNA-directed DNA polymerase activity
CAL15_RS14325	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS14330	COG1959	2 iron, 2 sulfur cluster binding
CAL15_RS14340	COG1610	YqeY-like protein
CAL15_RS14385	COG5265	(ABC) transporter
CAL15_RS14430	COG0776	regulation of translation
CAL15_RS14435	COG0072	phenylalanine-tRNA ligase activity
CAL15_RS14435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAL15_RS14440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CAL15_RS14445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CAL15_RS14450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CAL15_RS14465	COG1024	Enoyl-CoA hydratase
CAL15_RS14480	COG0583	DNA-binding transcription factor activity
CAL15_RS14490	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS14500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS14515	COG0606	chelatase, subunit chli
CAL15_RS14525	COG0347	Belongs to the P(II) protein family
CAL15_RS14530	COG0004	ammonium transporteR
CAL15_RS14545	COG2207	Transcriptional regulator
CAL15_RS14550	COG4221	oxidoreductase activity
CAL15_RS14565	COG2271	Major facilitator Superfamily
CAL15_RS14570	COG1253	flavin adenine dinucleotide binding
CAL15_RS14610	COG0402	S-adenosylhomocysteine deaminase activity
CAL15_RS14615	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL15_RS14615	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL15_RS14615	COG0506	proline dehydrogenase activity
CAL15_RS14620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAL15_RS14625	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS14630	COG3842	ATPase activity
CAL15_RS14635	COG1178	ABC-type Fe3 transport system permease component
CAL15_RS14645	COG3008	intermembrane lipid transfer
CAL15_RS14650	COG2995	paraquat-inducible protein a
CAL15_RS14655	COG0542	response to heat
CAL15_RS14660	COG4953	penicillin-binding protein 1C
CAL15_RS14665	COG2373	Large extracellular alpha-helical protein
CAL15_RS14670	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CAL15_RS14675	COG1278	Cold shock
CAL15_RS14685	COG0183	Belongs to the thiolase family
CAL15_RS14690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL15_RS14695	COG1570	exodeoxyribonuclease VII activity
CAL15_RS14700	COG0811	peptide transport
CAL15_RS14715	COG2835	tetraacyldisaccharide 4'-kinase activity
CAL15_RS14720	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CAL15_RS14725	COG0563	adenylate kinase activity
CAL15_RS14735	COG0728	peptidoglycan biosynthetic process
CAL15_RS14745	COG0268	Binds directly to 16S ribosomal RNA
CAL15_RS14765	COG2186	Transcriptional regulator
CAL15_RS14780	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS14790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL15_RS14800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAL15_RS14805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAL15_RS14810	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS14820	COG0745	RESPONSE REGULATOR receiver
CAL15_RS14825	COG3158	transport of potassium into the cell
CAL15_RS14830	COG0642	Histidine kinase
CAL15_RS14860	COG0776	regulation of translation
CAL15_RS14865	COG0626	cystathionine gamma-synthase activity
CAL15_RS14870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL15_RS14875	COG0557	exoribonuclease II activity
CAL15_RS14885	COG4589	Belongs to the CDS family
CAL15_RS14905	COG1271	oxidase subunit
CAL15_RS14910	COG1294	oxidase, subunit
CAL15_RS14925	COG2010	Cytochrome c
CAL15_RS14925	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS14930	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CAL15_RS14935	COG0069	glutamate synthase activity
CAL15_RS14940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL15_RS14950	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CAL15_RS14955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAL15_RS14990	COG0778	Nitroreductase
CAL15_RS15000	COG1742	UPF0060 membrane protein
CAL15_RS15005	COG0628	permease
CAL15_RS15025	COG3909	cytochrome
CAL15_RS15035	COG0625	glutathione transferase activity
CAL15_RS15040	COG0730	response to heat
CAL15_RS15050	COG0583	DNA-binding transcription factor activity
CAL15_RS15085	COG0247	lactate metabolic process
CAL15_RS15090	COG0277	FAD linked oxidase domain protein
CAL15_RS15095	COG0277	FAD linked oxidase domain protein
CAL15_RS15100	COG0277	FAD linked oxidase domain protein
CAL15_RS15105	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL15_RS15110	COG0312	modulator of DNA gyrase
CAL15_RS15130	COG0308	aminopeptidase N
CAL15_RS15135	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAL15_RS15155	COG0436	Aminotransferase
CAL15_RS15160	COG3737	Protein of unknown function (DUF498/DUF598)
CAL15_RS15165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAL15_RS15170	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAL15_RS15175	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CAL15_RS15180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL15_RS15200	COG0305	Participates in initiation and elongation during chromosome replication
CAL15_RS15205	COG0359	binds to the 23S rRNA
CAL15_RS15210	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CAL15_RS15215	COG2965	DNA replication, synthesis of RNA primer
CAL15_RS15220	COG0360	Binds together with S18 to 16S ribosomal RNA
CAL15_RS15225	COG1469	GTP cyclohydrolase I activity
CAL15_RS15235	COG0142	geranyltranstransferase activity
CAL15_RS15240	COG1722	exodeoxyribonuclease VII activity
CAL15_RS15245	COG1414	Transcriptional regulator
CAL15_RS15270	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL15_RS15275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAL15_RS15285	COG3842	ATPase activity
CAL15_RS15290	COG0583	DNA-binding transcription factor activity
CAL15_RS15310	COG0501	Belongs to the peptidase M48B family
CAL15_RS15330	COG1846	Transcriptional regulator
CAL15_RS15340	COG1566	PFAM secretion protein HlyD family protein
CAL15_RS15345	COG2814	Major facilitator Superfamily
CAL15_RS15350	COG0235	Class ii aldolase
CAL15_RS15355	COG0583	DNA-binding transcription factor activity
CAL15_RS15360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL15_RS15365	COG0747	negative chemotaxis
CAL15_RS15370	COG0601	transmembrane transport
CAL15_RS15375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS15410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL15_RS15425	COG0433	COG0433 Predicted ATPase
CAL15_RS15430	COG0217	transcriptional regulatory protein
CAL15_RS15435	COG0151	Belongs to the GarS family
CAL15_RS15445	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAL15_RS15450	COG0799	negative regulation of ribosome biogenesis
CAL15_RS15455	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CAL15_RS15465	COG1301	dicarboxylic acid transport
CAL15_RS15470	COG4191	Histidine kinase
CAL15_RS15475	COG2204	response regulator
CAL15_RS15515	COG3540	Alkaline phosphatase
CAL15_RS15520	COG3264	Mechanosensitive ion channel
CAL15_RS15520	COG1511	domain protein
CAL15_RS15575	COG4774	siderophore transport
CAL15_RS15580	COG0704	Plays a role in the regulation of phosphate uptake
CAL15_RS15590	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS15600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAL15_RS15605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CAL15_RS15610	COG1335	isochorismatase
CAL15_RS15625	COG1053	succinate dehydrogenase
CAL15_RS15630	COG1802	Transcriptional regulator
CAL15_RS15640	COG0737	Belongs to the 5'-nucleotidase family
CAL15_RS15650	COG1393	Belongs to the ArsC family
CAL15_RS15655	COG1177	transmembrane transport
CAL15_RS15660	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL15_RS15665	COG3842	ATPase activity
CAL15_RS15685	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CAL15_RS15695	COG2050	protein possibly involved in aromatic compounds catabolism
CAL15_RS15700	COG1024	Enoyl-CoA hydratase
CAL15_RS15710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL15_RS15715	COG2151	metal-sulfur cluster biosynthetic enzyme
CAL15_RS15720	COG3396	Phenylacetate-CoA oxygenase
CAL15_RS15725	COG3460	Phenylacetate-CoA oxygenase
CAL15_RS15730	COG3396	Phenylacetate-CoA oxygenase
CAL15_RS15735	COG3327	negative regulation of DNA-templated transcription, initiation
CAL15_RS15745	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CAL15_RS15750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CAL15_RS15755	COG0501	Belongs to the peptidase M48B family
CAL15_RS15760	COG1162	GTPase activity
CAL15_RS15770	COG0335	large ribosomal subunit rRNA binding
CAL15_RS15785	COG2895	sulfate adenylyltransferase (ATP) activity
CAL15_RS15795	COG0175	sulfate reduction
CAL15_RS15800	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL15_RS15805	COG4208	sulfate ABC transporter
CAL15_RS15810	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL15_RS15815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CAL15_RS15820	COG0450	alkyl hydroperoxide reductase
CAL15_RS15825	COG1960	acyl-CoA dehydrogenase activity
CAL15_RS15840	COG4774	siderophore transport
CAL15_RS15855	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAL15_RS15885	COG0583	DNA-binding transcription factor activity
CAL15_RS15890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL15_RS15925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL15_RS15930	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CAL15_RS15935	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CAL15_RS15945	COG0473	3-isopropylmalate dehydrogenase activity
CAL15_RS15950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CAL15_RS15975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAL15_RS15980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAL15_RS15985	COG0287	Prephenate dehydrogenase
CAL15_RS15990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL15_RS16000	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAL15_RS16015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAL15_RS16040	COG0582	viral genome integration into host DNA
CAL15_RS16045	COG0583	DNA-binding transcription factor activity
CAL15_RS16050	COG0625	glutathione transferase activity
CAL15_RS16055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL15_RS16055	COG1017	nitric oxide dioxygenase activity
CAL15_RS16060	COG2116	formate transmembrane transporter activity
CAL15_RS16075	COG4149	molybdate abc transporter
CAL15_RS16080	COG0725	ABC transporter, periplasmic molybdate-binding protein
CAL15_RS16090	COG2207	Transcriptional regulator
CAL15_RS16095	COG2264	protein methyltransferase activity
CAL15_RS16100	COG0667	Aldo Keto reductase
CAL15_RS16115	COG0589	response to stress
CAL15_RS16120	COG2951	lytic endotransglycosylase activity
CAL15_RS16125	COG2833	Protein of unknown function (DUF455)
CAL15_RS16140	COG1132	(ABC) transporter
CAL15_RS16145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL15_RS16145	COG0189	ligase activity
CAL15_RS16150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL15_RS16150	COG0189	ligase activity
CAL15_RS16160	COG3237	CsbD-like
CAL15_RS16185	COG0672	)-iron permease
CAL15_RS16200	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CAL15_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS16210	COG3243	poly(R)-hydroxyalkanoic acid synthase
CAL15_RS16220	COG0564	pseudouridine synthase activity
CAL15_RS16230	COG1199	ATP-dependent helicase activity
CAL15_RS16235	COG2183	response to ionizing radiation
CAL15_RS16270	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CAL15_RS16275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL15_RS16280	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL15_RS16285	COG0567	Dehydrogenase, E1 component
CAL15_RS16290	COG1522	sequence-specific DNA binding
CAL15_RS16300	COG0280	phosphate acetyltransferase
CAL15_RS16300	COG0281	malic enzyme
CAL15_RS16320	COG0372	Belongs to the citrate synthase family
CAL15_RS16325	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CAL15_RS16330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAL15_RS16335	COG1053	succinate dehydrogenase
CAL15_RS16340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CAL15_RS16345	COG2009	succinate dehydrogenase
CAL15_RS16350	COG2188	Transcriptional regulator
CAL15_RS16355	COG0039	L-malate dehydrogenase activity
CAL15_RS16380	COG2828	Protein conserved in bacteria
CAL15_RS16390	COG1981	membrane
CAL15_RS16420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL15_RS16430	COG2186	Transcriptional regulator
CAL15_RS16435	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS16450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS16455	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CAL15_RS16465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CAL15_RS16470	COG0148	phosphopyruvate hydratase activity
CAL15_RS16475	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CAL15_RS16480	COG0504	CTP synthase activity
CAL15_RS16520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS16525	COG0601	transmembrane transport
CAL15_RS16530	COG0747	negative chemotaxis
CAL15_RS16535	COG4172	Belongs to the ABC transporter superfamily
CAL15_RS16540	COG1446	asparaginase
CAL15_RS16550	COG2153	protein acetylation
CAL15_RS16565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL15_RS16595	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CAL15_RS16600	COG0697	spore germination
CAL15_RS16605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL15_RS16615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAL15_RS16625	COG0747	negative chemotaxis
CAL15_RS16630	COG0601	transmembrane transport
CAL15_RS16635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS16645	COG4608	Belongs to the ABC transporter superfamily
CAL15_RS16660	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CAL15_RS16665	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL15_RS16670	COG0791	NLP P60 protein
CAL15_RS16680	COG0583	DNA-binding transcription factor activity
CAL15_RS16710	COG0583	DNA-binding transcription factor activity
CAL15_RS16720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAL15_RS16740	COG1381	Involved in DNA repair and RecF pathway recombination
CAL15_RS16745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAL15_RS16750	COG0571	ribonuclease III activity
CAL15_RS16755	COG0681	Belongs to the peptidase S26 family
CAL15_RS16765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL15_RS16790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAL15_RS16795	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL15_RS16805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CAL15_RS16810	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAL15_RS16820	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CAL15_RS16825	COG1399	metal-binding, possibly nucleic acid-binding protein
CAL15_RS16830	COG0424	maF-like protein
CAL15_RS16840	COG3023	N-Acetylmuramoyl-L-alanine amidase
CAL15_RS16845	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CAL15_RS16850	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAL15_RS16855	COG0546	phosphoglycolate phosphatase activity
CAL15_RS16860	COG0564	pseudouridine synthase activity
CAL15_RS16865	COG1530	ribonuclease E activity
CAL15_RS16870	COG0477	Major facilitator Superfamily
CAL15_RS16895	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CAL15_RS16900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CAL15_RS16905	COG0159	tryptophan synthase activity
CAL15_RS16910	COG0133	tryptophan synthase activity
CAL15_RS16915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL15_RS16920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL15_RS16945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL15_RS16950	COG3228	Belongs to the MtfA family
CAL15_RS16960	COG0251	oxidation-reduction process
CAL15_RS16965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CAL15_RS16985	COG2878	Part of a membrane complex involved in electron transport
CAL15_RS16990	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAL15_RS16995	COG0411	ABC transporter
CAL15_RS17045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL15_RS17050	COG2917	probably involved in intracellular septation
CAL15_RS17060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL15_RS17070	COG3712	iron ion homeostasis
CAL15_RS17075	COG4774	siderophore transport
CAL15_RS17080	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAL15_RS17090	COG1196	nuclear chromosome segregation
CAL15_RS17095	COG0477	Major facilitator Superfamily
CAL15_RS17100	COG1573	uracil-dna glycosylase
CAL15_RS17120	COG0450	alkyl hydroperoxide reductase
CAL15_RS17125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL15_RS17130	COG1609	Transcriptional regulator
CAL15_RS17150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CAL15_RS17155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CAL15_RS17160	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAL15_RS17165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAL15_RS17170	COG0560	Phosphoserine phosphatase
CAL15_RS17190	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS17205	COG1007	ATP synthesis coupled electron transport
CAL15_RS17220	COG0713	ATP synthesis coupled electron transport
CAL15_RS17230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL15_RS17235	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CAL15_RS17240	COG1034	ATP synthesis coupled electron transport
CAL15_RS17250	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CAL15_RS17255	COG0649	NAD binding
CAL15_RS17260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL15_RS17265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL15_RS17270	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL15_RS17275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS17300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL15_RS17305	COG1597	lipid kinase activity
CAL15_RS17315	COG1309	transcriptional regulator
CAL15_RS17320	COG0500	methyltransferase
CAL15_RS17340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL15_RS17350	COG4251	negative regulation of phosphorylation
CAL15_RS17355	COG4191	Histidine kinase
CAL15_RS17355	COG0784	Response regulator, receiver
CAL15_RS17360	COG2733	membrane
CAL15_RS17365	COG0415	Belongs to the DNA photolyase family
CAL15_RS17385	COG0659	secondary active sulfate transmembrane transporter activity
CAL15_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS17400	COG0436	Aminotransferase
CAL15_RS17405	COG3685	Protein conserved in bacteria
CAL15_RS17430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAL15_RS17465	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAL15_RS17465	COG0475	glutathione-regulated potassium exporter activity
CAL15_RS17470	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL15_RS17475	COG0149	triose-phosphate isomerase activity
CAL15_RS17490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL15_RS17500	COG0583	DNA-binding transcription factor activity
CAL15_RS17540	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL15_RS17550	COG1185	polyribonucleotide nucleotidyltransferase activity
CAL15_RS17555	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAL15_RS17565	COG1183	phosphatidylcholine synthase activity
CAL15_RS17570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAL15_RS17575	COG0440	acetolactate synthase activity
CAL15_RS17580	COG0028	Belongs to the TPP enzyme family
CAL15_RS17585	COG1289	transmembrane transporter activity
CAL15_RS17595	COG3022	response to hydroperoxide
CAL15_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS17635	COG0840	transmembrane signaling receptor activity
CAL15_RS17640	COG2226	methyltransferase
CAL15_RS17655	COG0251	oxidation-reduction process
CAL15_RS17665	COG4191	Histidine kinase
CAL15_RS17670	COG4566	intracellular signal transduction
CAL15_RS17685	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CAL15_RS17700	COG4566	intracellular signal transduction
CAL15_RS17715	COG2200	EAL domain
CAL15_RS17735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAL15_RS17740	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAL15_RS17750	COG0747	negative chemotaxis
CAL15_RS17755	COG0601	transmembrane transport
CAL15_RS17780	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL15_RS17790	COG0745	RESPONSE REGULATOR receiver
CAL15_RS17795	COG2205	protein histidine kinase activity
CAL15_RS17800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CAL15_RS17805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CAL15_RS17810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CAL15_RS17825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAL15_RS17830	COG0583	DNA-binding transcription factor activity
CAL15_RS17835	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS17845	COG3246	L-lysine catabolic process to acetate
CAL15_RS17870	COG1193	negative regulation of DNA recombination
CAL15_RS17875	COG0492	ferredoxin-NADP+ reductase activity
CAL15_RS17880	COG1674	ftsk spoiiie
CAL15_RS17885	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CAL15_RS17900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS17905	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CAL15_RS17935	COG2010	Cytochrome c
CAL15_RS17935	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL15_RS17960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL15_RS17970	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS17985	COG3639	organic phosphonate transmembrane transporter activity
CAL15_RS17990	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CAL15_RS18000	COG0612	Peptidase, M16
CAL15_RS18005	COG0667	Aldo Keto reductase
CAL15_RS18010	COG1309	transcriptional regulator
CAL15_RS18050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL15_RS18055	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS18080	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS18090	COG0583	DNA-binding transcription factor activity
CAL15_RS18095	COG0484	heat shock protein binding
CAL15_RS18100	COG0443	Heat shock 70 kDa protein
CAL15_RS18110	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAL15_RS18120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAL15_RS18125	COG1420	regulation of RNA biosynthetic process
CAL15_RS18155	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS18170	COG0753	catalase activity
CAL15_RS18185	COG0497	DNA recombination
CAL15_RS18190	COG0735	belongs to the Fur family
CAL15_RS18195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL15_RS18215	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS18235	COG0582	viral genome integration into host DNA
CAL15_RS18285	COG1396	sequence-specific DNA binding
CAL15_RS18290	COG0583	DNA-binding transcription factor activity
CAL15_RS18330	COG2132	Multicopper oxidase
CAL15_RS18335	COG0745	RESPONSE REGULATOR receiver
CAL15_RS18340	COG5002	protein histidine kinase activity
CAL15_RS18350	COG0640	Transcriptional regulator
CAL15_RS18365	COG0798	PFAM Bile acid sodium symporter
CAL15_RS18375	COG1695	Transcriptional regulator
CAL15_RS18455	COG2003	Belongs to the UPF0758 family
CAL15_RS18510	COG3311	Transcriptional regulator
CAL15_RS18515	COG1569	PIN domain
CAL15_RS18520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL15_RS18670	COG0789	Transcriptional regulator
CAL15_RS18715	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAL15_RS18725	COG0789	Transcriptional regulator
CAL15_RS18745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAL15_RS18750	COG0629	single-stranded DNA binding
CAL15_RS18805	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS18810	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS18840	COG0477	Major facilitator Superfamily
CAL15_RS18855	COG2031	fatty acid transporter
CAL15_RS18870	COG3275	phosphorelay sensor kinase activity
CAL15_RS18890	COG2816	NAD+ diphosphatase activity
CAL15_RS18920	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CAL15_RS18925	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CAL15_RS18930	COG0167	dihydroorotate dehydrogenase activity
CAL15_RS18945	COG3180	Ammonia monooxygenase
CAL15_RS18950	COG1414	Transcriptional regulator
CAL15_RS18955	COG1058	Belongs to the CinA family
CAL15_RS18955	COG1546	Belongs to the CinA family
CAL15_RS18970	COG0513	Belongs to the DEAD box helicase family
CAL15_RS18995	COG0429	hydrolase of the alpha beta-hydrolase fold
CAL15_RS19000	COG4783	chaperone-mediated protein folding
CAL15_RS19005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CAL15_RS19025	COG0006	proline dipeptidase activity
CAL15_RS19035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL15_RS19085	COG2255	four-way junction helicase activity
CAL15_RS19090	COG0514	ATP-dependent DNA helicase (RecQ)
CAL15_RS19120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL15_RS19125	COG0850	regulation of cytokinetic process
CAL15_RS19130	COG2894	cell division
CAL15_RS19135	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CAL15_RS19150	COG0488	(ABC) transporter
CAL15_RS19165	COG1216	Glycosyl transferase, family 2
CAL15_RS19165	COG0463	Glycosyl transferase, family 2
CAL15_RS19170	COG0583	DNA-binding transcription factor activity
CAL15_RS19185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAL15_RS19215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAL15_RS19220	COG1538	Outer membrane efflux protein
CAL15_RS19225	COG0577	efflux transmembrane transporter activity
CAL15_RS19225	COG1136	(ABC) transporter
CAL15_RS19230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL15_RS19245	COG0259	pyridoxamine-phosphate oxidase activity
CAL15_RS19250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL15_RS19255	COG0579	oxidoreductase
CAL15_RS19265	COG3387	PFAM Glycoside hydrolase 15-related
CAL15_RS19320	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS19335	COG1573	uracil-dna glycosylase
CAL15_RS19340	COG0583	DNA-binding transcription factor activity
CAL15_RS19345	COG0583	DNA-binding transcription factor activity
CAL15_RS19355	COG1304	FMN binding
CAL15_RS19365	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS19375	COG0114	fumarate hydratase activity
CAL15_RS19380	COG0802	atpase or kinase
CAL15_RS19385	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAL15_RS19415	COG0586	Pfam SNARE associated Golgi protein
CAL15_RS19420	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAL15_RS19425	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CAL15_RS19440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS19450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAL15_RS19470	COG0617	tRNA 3'-terminal CCA addition
CAL15_RS19480	COG2301	Belongs to the HpcH HpaI aldolase family
CAL15_RS19485	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS19490	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CAL15_RS19495	COG0432	Pfam Uncharacterised protein family UPF0047
CAL15_RS19505	COG1024	Enoyl-CoA hydratase
CAL15_RS19515	COG0752	glycyl-tRNA synthetase alpha subunit
CAL15_RS19520	COG0751	glycine-tRNA ligase activity
CAL15_RS19525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL15_RS19530	COG0204	Acyl-transferase
CAL15_RS19550	COG0242	peptide deformylase activity
CAL15_RS19555	COG0700	Nucleoside recognition
CAL15_RS19560	COG0469	pyruvate kinase activity
CAL15_RS19565	COG1929	Belongs to the glycerate kinase type-1 family
CAL15_RS19570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CAL15_RS19575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL15_RS19590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CAL15_RS19610	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL15_RS19620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CAL15_RS19655	COG1573	uracil-dna glycosylase
CAL15_RS19665	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS19675	COG2175	clavaminate synthase activity
CAL15_RS19680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL15_RS19685	COG0583	DNA-binding transcription factor activity
CAL15_RS19695	COG1902	pentaerythritol trinitrate reductase activity
CAL15_RS19700	COG2610	gluconate transmembrane transporter activity
CAL15_RS19705	COG3866	Pectate lyase
CAL15_RS19710	COG1560	Kdo2-lipid A biosynthetic process
CAL15_RS19710	COG4783	chaperone-mediated protein folding
CAL15_RS19735	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS19740	COG0457	Tetratricopeptide repeat
CAL15_RS19800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS19805	COG2982	Protein involved in outer membrane biogenesis
CAL15_RS19810	COG2818	Glycosylase
CAL15_RS19845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL15_RS19875	COG2011	ABC-type metal ion transport system permease component
CAL15_RS19880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAL15_RS19885	COG1501	Belongs to the glycosyl hydrolase 31 family
CAL15_RS19890	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CAL15_RS19890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL15_RS19900	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS19905	COG1473	amidohydrolase
CAL15_RS19910	COG0583	DNA-binding transcription factor activity
CAL15_RS19915	COG2855	membrane
CAL15_RS19925	COG2239	Acts as a magnesium transporter
CAL15_RS19935	COG1522	sequence-specific DNA binding
CAL15_RS19950	COG0653	protein targeting
CAL15_RS19955	COG0739	heme binding
CAL15_RS19965	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CAL15_RS19980	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAL15_RS19985	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAL15_RS20010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAL15_RS20015	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL15_RS20020	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL15_RS20030	COG3116	cell division
CAL15_RS20035	COG0275	rRNA processing
CAL15_RS20040	COG2001	Belongs to the MraZ family
CAL15_RS20050	COG0488	(ABC) transporter
CAL15_RS20055	COG0418	dihydroorotase activity
CAL15_RS20060	COG1473	amidohydrolase
CAL15_RS20110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL15_RS20115	COG4654	Cytochrome c, class I
CAL15_RS20120	COG0129	dihydroxy-acid dehydratase activity
CAL15_RS20125	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAL15_RS20165	COG2084	Dehydrogenase
CAL15_RS20190	COG0494	nUDIX hydrolase
CAL15_RS20195	COG0442	prolyl-tRNA aminoacylation
CAL15_RS20200	COG0824	Thioesterase
CAL15_RS20220	COG0823	Involved in the tonB-independent uptake of proteins
CAL15_RS20250	COG1285	pathogenesis
CAL15_RS20255	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL15_RS20270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS20275	COG0697	spore germination
CAL15_RS20280	COG1280	lysine exporter protein (LysE YggA)
CAL15_RS20290	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL15_RS20300	COG1346	cytolysis
CAL15_RS20305	COG1380	Effector of murein hydrolase LrgA
CAL15_RS20310	COG0583	DNA-binding transcription factor activity
CAL15_RS20330	COG4948	Mandelate Racemase Muconate Lactonizing
CAL15_RS20335	COG0583	DNA-binding transcription factor activity
CAL15_RS20365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAL15_RS20370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL15_RS20375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL15_RS20380	COG0328	RNA-DNA hybrid ribonuclease activity
CAL15_RS20385	COG2226	methyltransferase
CAL15_RS20390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL15_RS20395	COG1388	LysM domain
CAL15_RS20395	COG0741	lytic transglycosylase activity
CAL15_RS20410	COG2979	Protein of unknown function (DUF533)
CAL15_RS20435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL15_RS20460	COG0643	Histidine kinase
CAL15_RS20460	COG2198	Histidine kinase
CAL15_RS20465	COG0840	transmembrane signaling receptor activity
CAL15_RS20470	COG0835	chemotaxis
CAL15_RS20475	COG2200	EAL domain
CAL15_RS20475	COG2199	diguanylate cyclase activity
CAL15_RS20475	COG2202	Pas domain
CAL15_RS20480	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL15_RS20485	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAL15_RS20500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAL15_RS20540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS20545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS20555	COG0583	DNA-binding transcription factor activity
CAL15_RS20575	COG1024	Enoyl-CoA hydratase
CAL15_RS20595	COG2079	MmgE PrpD family protein
CAL15_RS20605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAL15_RS20615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CAL15_RS20635	COG0114	fumarate hydratase activity
CAL15_RS20690	COG2080	2 iron, 2 sulfur cluster binding
CAL15_RS20705	COG0583	DNA-binding transcription factor activity
CAL15_RS20715	COG0840	transmembrane signaling receptor activity
CAL15_RS20725	COG3799	methylaspartate ammonia-lyase activity
CAL15_RS20745	COG2154	pterin-4-alpha-carbinolamine dehydratase
CAL15_RS20750	COG2719	SpoVR family
CAL15_RS20755	COG2718	Belongs to the UPF0229 family
CAL15_RS20760	COG2766	serine protein kinase
CAL15_RS20770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL15_RS20770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL15_RS20785	COG1686	Belongs to the peptidase S11 family
CAL15_RS20790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAL15_RS20795	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAL15_RS20810	COG1053	succinate dehydrogenase
CAL15_RS20820	COG1881	PFAM PEBP family protein
CAL15_RS20825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAL15_RS20830	COG0739	heme binding
CAL15_RS20835	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CAL15_RS20840	COG0316	Belongs to the HesB IscA family
CAL15_RS20850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAL15_RS20855	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAL15_RS20860	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CAL15_RS20865	COG0312	modulator of DNA gyrase
CAL15_RS20890	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS20895	COG0583	DNA-binding transcription factor activity
CAL15_RS20905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL15_RS20910	COG0477	Major facilitator Superfamily
CAL15_RS20925	COG0066	3-isopropylmalate dehydratase activity
CAL15_RS20930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAL15_RS20935	COG2188	Transcriptional regulator
CAL15_RS20945	COG1522	sequence-specific DNA binding
CAL15_RS20960	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAL15_RS20970	COG0762	integral membrane protein
CAL15_RS20975	COG3133	Outer membrane lipoprotein
CAL15_RS20980	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAL15_RS20990	COG2264	protein methyltransferase activity
CAL15_RS20995	COG0439	Biotin carboxylase
CAL15_RS21000	COG0511	ligase activity, forming carbon-carbon bonds
CAL15_RS21005	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAL15_RS21010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL15_RS21015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAL15_RS21020	COG3150	esterase
CAL15_RS21025	COG0557	exoribonuclease II activity
CAL15_RS21035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL15_RS21040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAL15_RS21050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL15_RS21055	COG0583	DNA-binding transcription factor activity
CAL15_RS21075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAL15_RS21080	COG1678	Uncharacterized ACR, COG1678
CAL15_RS21090	COG0351	phosphomethylpyrimidine kinase
CAL15_RS21095	COG0352	thiamine-phosphate diphosphorylase activity
CAL15_RS21100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAL15_RS21145	COG1024	Enoyl-CoA hydratase
CAL15_RS21150	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS21160	COG2199	diguanylate cyclase activity
CAL15_RS21160	COG2202	Pas domain
CAL15_RS21160	COG2200	EAL domain
CAL15_RS21190	COG0411	ABC transporter
CAL15_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS21240	COG0494	nUDIX hydrolase
CAL15_RS21255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL15_RS21270	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CAL15_RS21295	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAL15_RS21300	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CAL15_RS21310	COG0477	Major facilitator Superfamily
CAL15_RS21320	COG3468	outer membrane autotransporter barrel domain protein
CAL15_RS21335	COG1126	abc transporter atp-binding protein
CAL15_RS21340	COG0765	amino acid transport
CAL15_RS21345	COG4597	amino acid ABC transporter
CAL15_RS21350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS21355	COG2884	Cell division ATP-binding protein ftsE
CAL15_RS21360	COG2177	Part of the ABC transporter FtsEX involved in
CAL15_RS21365	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAL15_RS21370	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS21385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL15_RS21390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL15_RS21400	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS21410	COG2375	cellular response to nickel ion
CAL15_RS21415	COG1695	Transcriptional regulator
CAL15_RS21425	COG1194	a g-specific adenine glycosylase
CAL15_RS21460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAL15_RS21525	COG2022	thiamine diphosphate biosynthetic process
CAL15_RS21530	COG0351	phosphomethylpyrimidine kinase
CAL15_RS21535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL15_RS21545	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CAL15_RS21555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAL15_RS21570	COG2226	methyltransferase
CAL15_RS21575	COG0745	RESPONSE REGULATOR receiver
CAL15_RS21580	COG5002	protein histidine kinase activity
CAL15_RS21585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL15_RS21600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAL15_RS21605	COG1984	allophanate hydrolase subunit 2
CAL15_RS21620	COG3077	Addiction module antitoxin, RelB DinJ family
CAL15_RS21630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAL15_RS21635	COG1518	maintenance of DNA repeat elements
CAL15_RS21650	COG1857	crispr-associated protein
CAL15_RS21670	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL15_RS21675	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL15_RS21680	COG2080	2 iron, 2 sulfur cluster binding
CAL15_RS21685	COG2814	Major facilitator Superfamily
CAL15_RS21695	COG0657	acetylesterase activity
CAL15_RS21705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAL15_RS21710	COG1845	cytochrome c oxidase, subunit III
CAL15_RS21715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL15_RS21725	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CAL15_RS21735	COG4948	Mandelate Racemase Muconate Lactonizing
CAL15_RS21740	COG0583	DNA-binding transcription factor activity
CAL15_RS21745	COG4608	Belongs to the ABC transporter superfamily
CAL15_RS21750	COG0444	Belongs to the ABC transporter superfamily
CAL15_RS21755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS21765	COG0747	negative chemotaxis
CAL15_RS21790	COG0628	permease
CAL15_RS21795	COG0583	DNA-binding transcription factor activity
CAL15_RS21800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL15_RS21820	COG4977	sequence-specific DNA binding
CAL15_RS21825	COG2814	Major facilitator Superfamily
CAL15_RS21835	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CAL15_RS21840	COG2175	clavaminate synthase activity
CAL15_RS21855	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CAL15_RS21865	COG0583	DNA-binding transcription factor activity
CAL15_RS21870	COG2814	Major facilitator Superfamily
CAL15_RS21875	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS21880	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS21885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL15_RS21920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CAL15_RS21925	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CAL15_RS21930	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAL15_RS21940	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL15_RS21950	COG1414	Transcriptional regulator
CAL15_RS21960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL15_RS21970	COG0288	reversible hydration of carbon dioxide
CAL15_RS21990	COG3181	Tripartite tricarboxylate transporter family receptor
CAL15_RS22010	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS22035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAL15_RS22040	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL15_RS22045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAL15_RS22080	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CAL15_RS22085	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CAL15_RS22115	COG4191	Histidine kinase
CAL15_RS22115	COG0784	Response regulator, receiver
CAL15_RS22125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL15_RS22130	COG2818	Glycosylase
CAL15_RS22140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CAL15_RS22155	COG1116	anion transmembrane transporter activity
CAL15_RS22160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS22170	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS22180	COG0318	PFAM AMP-dependent synthetase and ligase
CAL15_RS22210	COG2814	Major facilitator Superfamily
CAL15_RS22220	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
CAL15_RS22220	COG0778	Nitroreductase
CAL15_RS22225	COG2186	Transcriptional regulator
CAL15_RS22230	COG4638	Rieske (2fe-2S)
CAL15_RS22260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL15_RS22270	COG3932	Exopolysaccharide synthesis, ExoD
CAL15_RS22275	COG0513	Belongs to the DEAD box helicase family
CAL15_RS22295	COG0142	geranyltranstransferase activity
CAL15_RS22310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAL15_RS22315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAL15_RS22320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAL15_RS22325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAL15_RS22340	COG0492	ferredoxin-NADP+ reductase activity
CAL15_RS22350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL15_RS22370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAL15_RS22375	COG0793	Belongs to the peptidase S41A family
CAL15_RS22380	COG4942	peptidase
CAL15_RS22385	COG0588	phosphoglycerate mutase activity
CAL15_RS22390	COG1054	Belongs to the UPF0176 family
CAL15_RS22395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAL15_RS22400	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CAL15_RS22405	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAL15_RS22420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CAL15_RS22425	COG1040	competence protein
CAL15_RS22430	COG2226	methyltransferase
CAL15_RS22435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CAL15_RS22445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAL15_RS22450	COG0569	domain protein
CAL15_RS22455	COG2204	response regulator
CAL15_RS22460	COG5000	phosphorelay sensor kinase activity
CAL15_RS22470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL15_RS22470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL15_RS22475	COG0546	phosphoglycolate phosphatase activity
CAL15_RS22485	COG0300	oxidoreductase activity
CAL15_RS22495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL15_RS22520	COG0546	phosphoglycolate phosphatase activity
CAL15_RS22525	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAL15_RS22535	COG0242	peptide deformylase activity
CAL15_RS22540	COG0758	DNA mediated transformation
CAL15_RS22555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS22560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS22620	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CAL15_RS22640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAL15_RS22645	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAL15_RS22650	COG0513	Belongs to the DEAD box helicase family
CAL15_RS22675	COG0617	tRNA 3'-terminal CCA addition
CAL15_RS22685	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAL15_RS22690	COG2308	Evidence 4 Homologs of previously reported genes of
CAL15_RS22745	COG1950	PFAM Membrane protein of
CAL15_RS22765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS22770	COG4948	Mandelate Racemase Muconate Lactonizing
CAL15_RS22775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL15_RS22785	COG0596	Alpha beta hydrolase
CAL15_RS22790	COG0066	3-isopropylmalate dehydratase activity
CAL15_RS22795	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAL15_RS22805	COG0583	DNA-binding transcription factor activity
CAL15_RS22810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL15_RS22815	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAL15_RS22825	COG1560	Kdo2-lipid A biosynthetic process
CAL15_RS22830	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAL15_RS22840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CAL15_RS22860	COG0735	belongs to the Fur family
CAL15_RS22865	COG0523	cobalamin synthesis protein
CAL15_RS22875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CAL15_RS22880	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CAL15_RS22890	COG2096	Adenosyltransferase
CAL15_RS22905	COG0667	Aldo Keto reductase
CAL15_RS22915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAL15_RS22920	COG0321	lipoyl(octanoyl) transferase activity
CAL15_RS22925	COG2921	Belongs to the UPF0250 family
CAL15_RS22930	COG1686	Belongs to the peptidase S11 family
CAL15_RS22950	COG1127	ABC transporter
CAL15_RS22955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL15_RS22960	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CAL15_RS22960	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CAL15_RS22965	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CAL15_RS22985	COG0859	PFAM glycosyl transferase family 9
CAL15_RS22990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CAL15_RS23005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAL15_RS23025	COG1215	transferase activity, transferring glycosyl groups
CAL15_RS23035	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL15_RS23050	COG0477	Major facilitator Superfamily
CAL15_RS23065	COG0673	inositol 2-dehydrogenase activity
CAL15_RS23085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS23095	COG1024	Enoyl-CoA hydratase
CAL15_RS23110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL15_RS23115	COG3568	Endonuclease Exonuclease Phosphatase
CAL15_RS23120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAL15_RS23155	COG0531	amino acid
CAL15_RS23160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL15_RS23165	COG1956	GAF domain-containing protein
CAL15_RS23170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL15_RS23175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CAL15_RS23180	COG2186	Transcriptional regulator
CAL15_RS23195	COG0251	oxidation-reduction process
CAL15_RS23220	COG0583	DNA-binding transcription factor activity
CAL15_RS23225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL15_RS23230	COG1024	Enoyl-CoA hydratase
CAL15_RS23275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL15_RS23280	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CAL15_RS23285	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS23290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL15_RS23315	COG1012	belongs to the aldehyde dehydrogenase family
CAL15_RS23325	COG1609	Transcriptional regulator
CAL15_RS23330	COG1671	Belongs to the UPF0178 family
CAL15_RS23355	COG2205	protein histidine kinase activity
CAL15_RS23370	COG2814	Major facilitator Superfamily
CAL15_RS23390	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CAL15_RS23395	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CAL15_RS23400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL15_RS23410	COG1965	Belongs to the frataxin family
CAL15_RS23425	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAL15_RS23430	COG1333	cytochrome c biogenesis protein
CAL15_RS23440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAL15_RS23450	COG4232	protein-disulfide reductase activity
CAL15_RS23455	COG1324	tolerance protein
CAL15_RS23470	COG1132	(ABC) transporter
CAL15_RS23485	COG3546	catalase activity
CAL15_RS23490	COG3685	Protein conserved in bacteria
CAL15_RS23495	COG0203	ribosomal protein L17
CAL15_RS23500	COG0202	RNA polymerase activity
CAL15_RS23505	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CAL15_RS23510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAL15_RS23515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAL15_RS23520	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAL15_RS23525	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAL15_RS23530	COG0201	protein transport
CAL15_RS23535	COG0200	Binds to the 23S rRNA
CAL15_RS23540	COG1841	ribosomal large subunit assembly
CAL15_RS23545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CAL15_RS23550	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAL15_RS23555	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAL15_RS23560	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CAL15_RS23565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CAL15_RS23570	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAL15_RS23575	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CAL15_RS23580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CAL15_RS23635	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAL15_RS23640	COG0255	Belongs to the universal ribosomal protein uL29 family
CAL15_RS23645	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAL15_RS23650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAL15_RS23655	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CAL15_RS23660	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAL15_RS23665	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAL15_RS23670	COG0089	rRNA binding
CAL15_RS23675	COG0088	Forms part of the polypeptide exit tunnel
CAL15_RS23680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAL15_RS23735	COG0051	transcription antitermination factor activity, RNA binding
CAL15_RS23740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL15_RS23745	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL15_RS23750	COG0049	tRNA binding
CAL15_RS23755	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAL15_RS23765	COG0745	RESPONSE REGULATOR receiver
CAL15_RS23770	COG5002	protein histidine kinase activity
CAL15_RS23785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAL15_RS23790	COG0085	RNA polymerase activity
CAL15_RS23795	COG0222	ribosome binding
CAL15_RS23800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAL15_RS23805	COG0081	regulation of translation
CAL15_RS23810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAL15_RS23820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL15_RS23830	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL15_RS23850	COG0252	asparaginase activity
CAL15_RS23855	COG1475	DNA binding
CAL15_RS23860	COG0456	acetyltransferase
CAL15_RS23865	COG1192	Involved in chromosome partitioning
CAL15_RS23870	COG0357	Ribosomal RNA small subunit methyltransferase G
CAL15_RS23875	COG0445	tRNA wobble uridine modification
CAL15_RS23880	COG1278	Cold shock
CAL15_RS23885	COG0436	Aminotransferase
CAL15_RS23920	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CAL15_RS23935	COG1028	Short-chain dehydrogenase reductase Sdr
CAL15_RS23950	COG0489	protein tyrosine kinase activity
CAL15_RS23990	COG1216	Glycosyl transferase, family 2
CAL15_RS23990	COG1442	glycosyl transferase family 8
CAL15_RS24000	COG1596	polysaccharide export
CAL15_RS24020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAL15_RS24025	COG0662	Cupin 2, conserved barrel domain protein
CAL15_RS24025	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CAL15_RS24040	COG0489	protein tyrosine kinase activity
CAL15_RS24045	COG1215	transferase activity, transferring glycosyl groups
CAL15_RS24050	COG1215	transferase activity, transferring glycosyl groups
CAL15_RS24055	COG1215	transferase activity, transferring glycosyl groups
CAL15_RS24060	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CAL15_RS24065	COG0457	Tetratricopeptide repeat
CAL15_RS24090	COG2130	NADP-dependent
CAL15_RS24105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL15_RS24130	COG0154	amidase activity
CAL15_RS24135	COG4166	transmembrane transport
CAL15_RS24140	COG0601	transmembrane transport
CAL15_RS24145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS24165	COG0154	amidase activity
CAL15_RS24170	COG0154	amidase activity
CAL15_RS24190	COG0436	Aminotransferase
CAL15_RS24195	COG0251	oxidation-reduction process
CAL15_RS24200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL15_RS24210	COG0438	transferase activity, transferring glycosyl groups
CAL15_RS24215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CAL15_RS24225	COG0601	transmembrane transport
CAL15_RS24230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL15_RS24235	COG0444	Belongs to the ABC transporter superfamily
CAL15_RS24240	COG4608	Belongs to the ABC transporter superfamily
CAL15_RS24245	COG1473	amidohydrolase
CAL15_RS24250	COG2175	clavaminate synthase activity
CAL15_RS24260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CAL15_RS24265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL15_RS24270	COG0753	catalase activity
CAL15_RS24275	COG0706	membrane insertase activity
CAL15_RS24280	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAL15_RS24285	COG0594	ribonuclease P activity
CAL15_RS24290	COG0230	Belongs to the bacterial ribosomal protein bL34 family