CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 Gene3D G3DSA:3.50.50.60 284 358 8.8E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 Gene3D G3DSA:3.50.50.60 3 182 8.8E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 SUPERFAMILY SSF51905 284 364 1.05E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 SUPERFAMILY SSF51905 3 177 1.05E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.6E-20 T 06-07-2017 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 1.6E-20 T 06-07-2017 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 1.6E-20 T 06-07-2017 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 1.6E-20 T 06-07-2017 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 Pfam PF01494 FAD binding domain 3 356 9.0E-22 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS25200 1e72cacdfd602b0a6fc6b9c14730f276 418 SUPERFAMILY SSF54373 182 288 2.55E-32 T 06-07-2017 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 Hamap MF_00484 Glycogen synthase [glgA]. 4 485 38.365 T 06-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 Pfam PF00534 Glycosyl transferases group 1 288 451 4.7E-15 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 SUPERFAMILY SSF53756 5 486 4.19E-106 T 06-07-2017 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 Pfam PF08323 Starch synthase catalytic domain 5 239 2.1E-71 T 06-07-2017 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 Gene3D G3DSA:3.40.50.2000 254 466 3.4E-61 T 06-07-2017 CAL12_RS16140 b99d7fb243958591e747a74846f06117 540 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 5 485 9.0E-152 T 06-07-2017 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 Gene3D G3DSA:1.10.10.10 6 80 3.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 SMART SM00345 21 79 1.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.9E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 50 69 7.7E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 50 7.7E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 Gene3D G3DSA:1.20.120.530 82 218 7.6E-33 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 SMART SM00895 89 213 9.4E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 Pfam PF07729 FCD domain 89 212 3.8E-29 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 SUPERFAMILY SSF46785 10 83 7.68E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 79 1.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04630 552e3aed8b6999cc53c6e5a5b44894e4 235 SUPERFAMILY SSF48008 85 218 8.11E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 452 7.8E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SUPERFAMILY SSF158472 187 234 1.12E-5 T 06-07-2017 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Pfam PF00672 HAMP domain 167 233 9.6E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Gene3D G3DSA:1.10.287.130 228 293 2.5E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 3.0E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 3.0E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 3.0E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 3.0E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SMART SM00388 238 297 3.9E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SUPERFAMILY SSF55874 296 453 3.67E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Gene3D G3DSA:3.30.565.10 303 452 3.9E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SUPERFAMILY SSF47384 222 293 3.34E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SMART SM00387 339 453 9.1E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 SMART SM00304 185 237 1.4E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 51 157 1.6E-39 T 06-07-2017 IPR032408 Sensor histidine kinase RisS, periplasmic domain CAL12_RS19590 f06a6d72543579b1be460595b0f599a5 463 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 293 5.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 Gene3D G3DSA:3.40.50.300 11 265 8.8E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 328 3.5E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 SMART SM00382 41 241 2.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 SUPERFAMILY SSF52540 12 262 3.85E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 6.4E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS13455 c354e14e0d90d5067e791a07d10ea449 344 Pfam PF00005 ABC transporter 33 191 8.6E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27760 1dd7f3970494de232410e4d54e3c5334 174 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 06-07-2017 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27760 1dd7f3970494de232410e4d54e3c5334 174 SUPERFAMILY SSF160369 3 171 9.29E-55 T 06-07-2017 CAL12_RS27760 1dd7f3970494de232410e4d54e3c5334 174 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.724 T 06-07-2017 IPR022973 Ribosomal protein L10 CAL12_RS27760 1dd7f3970494de232410e4d54e3c5334 174 Pfam PF00466 Ribosomal protein L10 4 100 1.5E-23 T 06-07-2017 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CAL12_RS27760 1dd7f3970494de232410e4d54e3c5334 174 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 143 4.0E-4 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Pfam PF00476 DNA polymerase family A 528 902 4.3E-150 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:3.30.420.10 308 520 1.1E-75 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 768 779 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 707 720 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 756 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 700 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 852 865 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 838 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 790 801 1.8E-67 T 06-07-2017 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SMART SM00475 2 259 1.4E-111 T 06-07-2017 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Pfam PF01612 3'-5' exonuclease 310 495 3.6E-37 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 250 8.0E-22 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SUPERFAMILY SSF53098 309 494 4.41E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:1.20.1060.10 521 641 1.2E-35 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 9.7E-53 T 06-07-2017 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:1.10.150.20 182 241 1.1E-22 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 TIGRFAM TIGR00593 pola: DNA polymerase I 5 905 3.0E-270 T 06-07-2017 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:1.10.150.20 689 794 6.7E-36 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SMART SM00474 310 496 1.4E-31 T 06-07-2017 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 ProSitePatterns PS00447 DNA polymerase family A signature. 731 750 - T 06-07-2017 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:3.40.50.1010 3 181 3.7E-68 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SMART SM00482 664 869 5.4E-110 T 06-07-2017 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SMART SM00279 169 204 1.4E-10 T 06-07-2017 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SUPERFAMILY SSF88723 2 166 1.4E-56 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SUPERFAMILY SSF56672 502 905 3.11E-151 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:3.30.70.370 642 688 2.2E-62 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 Gene3D G3DSA:3.30.70.370 795 905 2.2E-62 T 06-07-2017 CAL12_RS18355 3cd0f589a7a4352f235110aa92c9cebb 905 SUPERFAMILY SSF47807 167 284 3.89E-29 T 06-07-2017 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 Pfam PF13476 AAA domain 5 268 1.2E-11 T 06-07-2017 CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 Gene3D G3DSA:3.40.50.300 2 169 1.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 Gene3D G3DSA:3.40.50.300 205 233 1.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 Gene3D G3DSA:3.40.50.300 781 866 1.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 Gene3D G3DSA:3.40.50.300 533 556 1.2E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 SUPERFAMILY SSF52540 774 866 9.16E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 SUPERFAMILY SSF52540 2 114 9.16E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01985 7ac2a5f7e9145f99fb0f1ee876935193 884 SUPERFAMILY SSF52540 247 278 9.16E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Pfam PF00975 Thioesterase domain 654 751 4.9E-21 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:3.40.50.980 179 338 8.0E-45 T 06-07-2017 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:3.30.300.30 413 507 1.4E-20 T 06-07-2017 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Pfam PF00501 AMP-binding enzyme 17 419 4.2E-90 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Pfam PF00550 Phosphopantetheine attachment site 561 623 1.1E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 SUPERFAMILY SSF47336 557 623 9.55E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 SUPERFAMILY SSF53474 645 891 1.53E-40 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 SMART SM00824 Thioesterase 657 887 5.4E-4 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:2.30.38.10 339 408 7.6E-12 T 06-07-2017 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 31 440 6.1E-108 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:3.40.50.980 8 178 9.6E-40 T 06-07-2017 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 SUPERFAMILY SSF56801 6 507 9.81E-123 T 06-07-2017 CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:1.10.1200.10 557 628 1.8E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 ProSitePatterns PS00012 Phosphopantetheine attachment site. 582 597 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:3.40.50.1820 828 892 8.1E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 Gene3D G3DSA:3.40.50.1820 646 751 8.1E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24360 d8c66f8836ae1f62d93747ec6e605da8 903 SMART SM00823 Phosphopantetheine attachment site 559 627 1.0E-7 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS24785 c667cc9bee287c52f45c4ea4ec74e4ac 183 Gene3D G3DSA:1.10.60.30 31 105 1.0E-26 T 06-07-2017 IPR023153 PSPTO4464-like domain CAL12_RS24785 c667cc9bee287c52f45c4ea4ec74e4ac 183 Gene3D G3DSA:1.10.60.30 107 181 9.0E-23 T 06-07-2017 IPR023153 PSPTO4464-like domain CAL12_RS24785 c667cc9bee287c52f45c4ea4ec74e4ac 183 PIRSF PIRSF016183 5 183 8.0E-59 T 06-07-2017 IPR006839 Ribosome-associated, YjgA CAL12_RS24785 c667cc9bee287c52f45c4ea4ec74e4ac 183 SUPERFAMILY SSF158710 31 181 3.66E-41 T 06-07-2017 CAL12_RS24785 c667cc9bee287c52f45c4ea4ec74e4ac 183 Pfam PF04751 Protein of unknown function (DUF615) 21 179 1.6E-49 T 06-07-2017 IPR006839 Ribosome-associated, YjgA CAL12_RS26155 d7837df2dd15b89d46cee82f2306ea8b 261 Gene3D G3DSA:3.40.190.10 24 151 1.4E-55 T 06-07-2017 CAL12_RS26155 d7837df2dd15b89d46cee82f2306ea8b 261 PIRSF PIRSF002854 1 261 3.6E-108 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS26155 d7837df2dd15b89d46cee82f2306ea8b 261 SUPERFAMILY SSF53850 25 261 5.04E-87 T 06-07-2017 CAL12_RS26155 d7837df2dd15b89d46cee82f2306ea8b 261 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 43 260 2.0E-72 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS26155 d7837df2dd15b89d46cee82f2306ea8b 261 Pfam PF03180 NLPA lipoprotein 26 261 6.4E-101 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 Pfam PF00561 alpha/beta hydrolase fold 85 316 4.1E-25 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 125 6.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 PRINTS PR00111 Alpha/beta hydrolase fold signature 154 167 6.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 PRINTS PR00111 Alpha/beta hydrolase fold signature 168 181 6.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 PRINTS PR00111 Alpha/beta hydrolase fold signature 276 290 6.5E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 SUPERFAMILY SSF53474 64 329 2.62E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05835 564879ba02433f9fffddf15b7f4aecea 334 Gene3D G3DSA:3.40.50.1820 65 329 5.6E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 SUPERFAMILY SSF56770 10 152 1.13E-65 T 06-07-2017 CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 146 2.8E-22 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 Gene3D G3DSA:3.40.50.700 22 149 1.8E-31 T 06-07-2017 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 119 135 - T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 2 152 41.189 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19705 2236cc8af53f1d732ce154f763f12dab 159 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 12 152 2.1E-75 T 06-07-2017 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 SUPERFAMILY SSF47203 231 397 3.87E-24 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Gene3D G3DSA:1.10.540.10 2 120 1.1E-25 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Gene3D G3DSA:2.40.110.10 124 220 3.8E-36 T 06-07-2017 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 SUPERFAMILY SSF56645 2 244 1.2E-75 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Gene3D G3DSA:1.20.140.10 221 397 2.7E-33 T 06-07-2017 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 1.3E-19 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 2.4E-21 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS01405 fb79d201717275991ba15979fe56042a 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 394 3.8E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 Gene3D G3DSA:1.10.10.10 20 87 6.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 Gene3D G3DSA:3.90.1150.10 374 479 1.1E-7 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.7E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.7E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 81 1.5E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 Gene3D G3DSA:3.40.640.10 171 372 1.2E-43 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 SUPERFAMILY SSF53383 129 479 4.7E-77 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 SUPERFAMILY SSF46785 16 88 7.67E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 Pfam PF00155 Aminotransferase class I and II 169 472 4.0E-25 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS08170 3baf3672e519e6af5bb8d4cfcce7821f 481 SMART SM00345 25 84 1.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Pfam PF00005 ABC transporter 21 162 3.4E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 SUPERFAMILY SSF50331 237 359 1.09E-22 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 SUPERFAMILY SSF52540 4 244 4.88E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Gene3D G3DSA:3.40.50.300 3 235 1.0E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Pfam PF08402 TOBE domain 279 346 8.4E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Gene3D G3DSA:2.40.50.100 240 283 7.8E-8 T 06-07-2017 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Gene3D G3DSA:2.40.50.100 345 359 7.8E-8 T 06-07-2017 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 SMART SM00382 29 212 1.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15540 9870fca30005fc337fabb7fd93bef093 362 Gene3D G3DSA:2.40.50.140 284 343 2.9E-13 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF52540 5 221 9.81E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF50465 304 396 1.44E-36 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.4E-17 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:2.40.30.10 211 300 6.7E-36 T 06-07-2017 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.392 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 4.1E-15 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 7.9E-59 T 06-07-2017 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.4E-228 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF50447 207 303 1.28E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.7E-33 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:2.40.30.10 302 395 2.6E-46 T 06-07-2017 CAL12_RS27665 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:3.40.50.300 5 210 3.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF52540 5 221 9.81E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF50465 304 396 1.44E-36 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.3E-25 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.4E-17 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:2.40.30.10 211 300 6.7E-36 T 06-07-2017 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.392 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 4.1E-15 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 7.9E-59 T 06-07-2017 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.4E-228 T 06-07-2017 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 SUPERFAMILY SSF50447 207 303 1.28E-30 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 3.7E-33 T 06-07-2017 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:2.40.30.10 302 395 2.6E-46 T 06-07-2017 CAL12_RS27790 428b0b4a1de8245cde5aafada62a5d8c 396 Gene3D G3DSA:3.40.50.300 5 210 3.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 PIRSF PIRSF500136 3 424 1.2E-148 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 203 291 5.8E-24 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 SUPERFAMILY SSF48179 201 292 5.78E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 SUPERFAMILY SSF51735 8 192 2.19E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 SMART SM00984 318 418 1.0E-34 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 8 412 9.2E-121 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 Gene3D G3DSA:3.40.50.720 233 418 2.9E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 PIRSF PIRSF000124 7 422 4.1E-54 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 SUPERFAMILY SSF52413 301 417 2.09E-28 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 Gene3D G3DSA:3.40.50.720 6 223 7.6E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 8 180 2.6E-35 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS02700 c60d9eb007872d4d465ebcaad465348d 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 418 1.3E-20 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 Pfam PF02911 Formyl transferase, C-terminal domain 211 309 3.2E-20 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 SUPERFAMILY SSF53328 1 214 1.44E-66 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 311 1.2E-82 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 SUPERFAMILY SSF50486 212 311 5.69E-24 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 Gene3D G3DSA:3.40.50.170 1 212 4.5E-78 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 Pfam PF00551 Formyl transferase 1 188 7.1E-43 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 140 163 - T 06-07-2017 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 313 35.157 T 06-07-2017 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CAL12_RS26375 50d64f3439380d0f50b80e146effa3d8 314 Gene3D G3DSA:3.10.25.10 214 312 4.8E-25 T 06-07-2017 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS17485 6bf8d2704e17bdfe2dd25762f0a0485a 254 Gene3D G3DSA:3.20.20.60 4 252 6.1E-74 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS17485 6bf8d2704e17bdfe2dd25762f0a0485a 254 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 7 253 1.7E-135 T 06-07-2017 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 CAL12_RS17485 6bf8d2704e17bdfe2dd25762f0a0485a 254 SUPERFAMILY SSF51621 5 253 6.28E-80 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS17485 6bf8d2704e17bdfe2dd25762f0a0485a 254 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 243 7.2E-53 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAL12_RS08310 bd8a37695d8cf565191d5e894d29f537 218 Gene3D G3DSA:1.10.150.240 17 71 1.2E-8 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAL12_RS08310 bd8a37695d8cf565191d5e894d29f537 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 86 176 2.0E-11 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS08310 bd8a37695d8cf565191d5e894d29f537 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 3.8E-34 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS08310 bd8a37695d8cf565191d5e894d29f537 218 SUPERFAMILY SSF56784 4 212 6.08E-58 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS08310 bd8a37695d8cf565191d5e894d29f537 218 Gene3D G3DSA:3.40.50.1000 72 213 3.0E-41 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS18755 93ace9f6e21bcdfbb8018d268aed134e 293 SUPERFAMILY SSF161098 29 279 5.61E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18755 93ace9f6e21bcdfbb8018d268aed134e 293 Gene3D G3DSA:1.10.3720.10 32 283 8.6E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18755 93ace9f6e21bcdfbb8018d268aed134e 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 280 1.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18755 93ace9f6e21bcdfbb8018d268aed134e 293 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 24 286 2.3E-120 T 06-07-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CAL12_RS18755 93ace9f6e21bcdfbb8018d268aed134e 293 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 25 283 9.8E-95 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 SUPERFAMILY SSF46785 8 120 3.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 Gene3D G3DSA:3.40.190.10 100 192 2.2E-14 T 06-07-2017 CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 Pfam PF03466 LysR substrate binding domain 98 301 1.7E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 4.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 SUPERFAMILY SSF53850 100 306 1.33E-31 T 06-07-2017 CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 Gene3D G3DSA:1.10.10.10 11 90 9.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20630 43ce00a0905ea4643aa5951f41a927eb 310 Gene3D G3DSA:3.40.190.10 193 271 1.1E-11 T 06-07-2017 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 Gene3D G3DSA:2.40.50.140 671 758 8.0E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 ProSitePatterns PS01175 Ribonuclease II family signature. 577 601 - T 06-07-2017 IPR022966 Ribonuclease II/R, conserved site CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 TIGRFAM TIGR02063 RNase_R: ribonuclease R 30 753 2.2E-248 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SUPERFAMILY SSF50249 79 157 2.53E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 91 752 8.9E-207 T 06-07-2017 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SMART SM00316 669 752 2.0E-12 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SMART SM00316 91 152 58.0 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 Pfam PF08206 Ribonuclease B OB domain 98 154 2.8E-20 T 06-07-2017 IPR013223 Ribonuclease B, N-terminal OB domain CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SMART SM00955 270 610 7.3E-179 T 06-07-2017 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SMART SM00357 97 155 3.3E-11 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SUPERFAMILY SSF50249 671 751 1.64E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 Hamap MF_01895 Ribonuclease R [rnr]. 49 752 54.174 T 06-07-2017 IPR011805 Ribonuclease R GO:0003723|GO:0004518 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 Pfam PF00773 RNB domain 270 609 6.5E-100 T 06-07-2017 CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SUPERFAMILY SSF50249 230 668 3.26E-134 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 SUPERFAMILY SSF50249 149 247 8.91E-22 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17595 536ef1ebac0d5c2af76af80eb9af2494 821 Pfam PF00575 S1 RNA binding domain 669 749 2.3E-10 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 SMART SM00862 159 235 4.8E-18 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 Pfam PF00072 Response regulator receiver domain 7 118 2.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 SMART SM00448 5 117 1.9E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 Gene3D G3DSA:1.10.10.10 136 237 5.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 Gene3D G3DSA:3.40.50.2300 6 127 3.1E-40 T 06-07-2017 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 SUPERFAMILY SSF52172 6 135 9.11E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 SUPERFAMILY SSF46894 136 235 3.68E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS04775 2040048715118fc499b7bceef4d88f87 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 235 9.7E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS06100 54b57e823e1aa11d08ad05471e0f6fd8 421 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 146 416 1.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06100 54b57e823e1aa11d08ad05471e0f6fd8 421 SUPERFAMILY SSF53850 207 384 7.78E-7 T 06-07-2017 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 Pfam PF03466 LysR substrate binding domain 89 295 3.6E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 Gene3D G3DSA:3.40.190.10 195 269 2.0E-16 T 06-07-2017 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.2E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 Gene3D G3DSA:3.40.190.10 89 194 1.1E-18 T 06-07-2017 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 SUPERFAMILY SSF46785 1 83 6.81E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 SUPERFAMILY SSF53850 89 301 3.37E-41 T 06-07-2017 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 Gene3D G3DSA:1.10.10.10 1 84 1.7E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27235 fce18d61c04df17496d2e455235ce5f0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.1E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.1E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.1E-31 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 Gene3D G3DSA:3.90.930.12 2 82 2.3E-28 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 34.625 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 SUPERFAMILY SSF56053 83 177 4.32E-34 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 Pfam PF00347 Ribosomal protein L6 11 82 1.6E-16 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 Pfam PF00347 Ribosomal protein L6 90 164 1.6E-17 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 06-07-2017 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 PIRSF PIRSF002162 1 177 6.6E-49 T 06-07-2017 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.5E-70 T 06-07-2017 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 Gene3D G3DSA:3.90.930.12 83 177 4.7E-38 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27550 46cdeebb77c977260506a5240b53c2e7 177 SUPERFAMILY SSF56053 1 82 2.22E-25 T 06-07-2017 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 ProSitePatterns PS00194 Thioredoxin family active site. 589 607 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 SUPERFAMILY SSF74863 51 170 7.32E-33 T 06-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 29 681 33.316 T 06-07-2017 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 SUPERFAMILY SSF52833 568 678 2.08E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Pfam PF11412 Disulphide bond corrector protein DsbC 53 169 1.6E-32 T 06-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Gene3D G3DSA:3.40.30.10 590 681 6.5E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 258 459 2.1E-17 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Gene3D G3DSA:2.60.40.1250 48 170 8.4E-37 T 06-07-2017 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Pfam PF13899 Thioredoxin-like 575 654 9.8E-10 T 06-07-2017 CAL12_RS27480 72bf02b93a044267e9303db13afd22f0 683 Gene3D G3DSA:3.40.30.10 540 589 2.0E-4 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 TIGRFAM TIGR03178 allantoinase: allantoinase 3 438 2.2E-115 T 06-07-2017 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 Gene3D G3DSA:3.20.20.140 70 414 8.5E-112 T 06-07-2017 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 SUPERFAMILY SSF51556 55 374 3.92E-100 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 ProSitePatterns PS00483 Dihydroorotase signature 2. 308 319 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 Gene3D G3DSA:2.30.40.10 3 69 1.7E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 431 5.7E-99 T 06-07-2017 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 SUPERFAMILY SSF51338 1 54 2.57E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 SUPERFAMILY SSF51338 374 444 2.57E-32 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS13670 c912a468ed00962bb3a77774a0b4d8b4 454 Pfam PF01979 Amidohydrolase family 52 428 7.1E-33 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 SUPERFAMILY SSF46894 138 210 1.67E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 4.2E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 Gene3D G3DSA:1.10.10.10 120 210 1.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 SMART SM00421 147 204 2.6E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.0E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 SUPERFAMILY SSF52172 4 179 1.47E-6 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07950 fe3902ee73a3ef9497de88c2bc27dc73 229 Gene3D G3DSA:3.40.50.2300 5 119 4.3E-4 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF56801 2746 2822 1.57E-147 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF56801 2191 2698 1.57E-147 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00501 AMP-binding enzyme 532 980 1.1E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00501 AMP-binding enzyme 2229 2660 2.6E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 1224 1403 1.45E-35 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.40.50.980 2223 2404 2.7E-43 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.40.50.980 526 707 1.1E-43 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SMART SM00823 Phosphopantetheine attachment site 2809 2880 0.0015 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SMART SM00823 Phosphopantetheine attachment site 1108 1176 0.0036 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.30.300.30 2739 2812 1.7E-35 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.30.300.30 2655 2694 1.7E-35 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.30.300.30 975 1111 1.9E-36 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00550 Phosphopantetheine attachment site 1110 1170 1.4E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00550 Phosphopantetheine attachment site 2811 2872 8.8E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF56801 835 1121 3.01E-149 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF56801 478 806 3.01E-149 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1132 1147 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 1929 2186 4.56E-47 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 234 481 2.11E-52 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF47336 1100 1170 4.71E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 1724 1743 4.82E-40 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 1778 1943 4.82E-40 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 1448 1694 1.11E-36 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF13745 HxxPF-repeated domain 368 460 1.6E-20 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00668 Condensation domain 1787 2053 2.3E-49 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00668 Condensation domain 1223 1559 7.2E-52 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF00668 Condensation domain 49 342 7.6E-67 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:1.10.1200.10 2813 2872 9.6E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:1.10.1200.10 1112 1173 1.2E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:2.30.38.10 2573 2650 3.1E-26 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:2.30.38.10 893 970 8.1E-27 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2390 2401 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1565 1717 3.5E-38 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 ProSitePatterns PS00455 Putative AMP-binding domain signature. 693 704 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF13193 AMP-binding enzyme C-terminal domain 2739 2784 3.1E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Pfam PF13193 AMP-binding enzyme C-terminal domain 1037 1083 5.5E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2271 2684 1.9E-133 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF47336 2801 2872 3.8E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 SUPERFAMILY SSF52777 49 228 5.89E-47 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.40.50.980 714 796 5.9E-44 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.40.50.980 833 892 5.9E-44 T 06-07-2017 CAL12_RS11055 8936615ce0af3603c90766f9ff6d7faa 2901 Gene3D G3DSA:3.40.50.980 2411 2572 2.6E-44 T 06-07-2017 CAL12_RS03970 063d5e076e9259cccd9328b486396041 156 SMART SM00347 34 133 2.6E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS03970 063d5e076e9259cccd9328b486396041 156 SUPERFAMILY SSF46785 17 143 3.04E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03970 063d5e076e9259cccd9328b486396041 156 Pfam PF12802 MarR family 40 97 2.0E-10 T 06-07-2017 CAL12_RS03970 063d5e076e9259cccd9328b486396041 156 Gene3D G3DSA:1.10.10.10 19 141 6.3E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03195 8fc5ce3d6867a5a1635d6a5786fecfee 352 Pfam PF13343 Bacterial extracellular solute-binding protein 87 333 1.9E-30 T 06-07-2017 CAL12_RS03195 8fc5ce3d6867a5a1635d6a5786fecfee 352 Gene3D G3DSA:3.40.190.10 150 291 2.8E-30 T 06-07-2017 CAL12_RS03195 8fc5ce3d6867a5a1635d6a5786fecfee 352 SUPERFAMILY SSF53850 44 346 9.88E-50 T 06-07-2017 CAL12_RS03195 8fc5ce3d6867a5a1635d6a5786fecfee 352 Gene3D G3DSA:3.40.190.10 49 149 1.8E-6 T 06-07-2017 CAL12_RS03295 2ee5ea278b49e4f0a742af22a7484986 326 SUPERFAMILY SSF53850 114 287 7.17E-15 T 06-07-2017 CAL12_RS03295 2ee5ea278b49e4f0a742af22a7484986 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 1.5E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03295 2ee5ea278b49e4f0a742af22a7484986 326 PIRSF PIRSF017082 1 326 2.0E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07105 d1b29a82a1c4726393cc1c6d0fdcaa83 102 Gene3D G3DSA:3.10.20.30 10 87 1.2E-4 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS07105 d1b29a82a1c4726393cc1c6d0fdcaa83 102 SUPERFAMILY SSF54292 17 94 9.57E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS07105 d1b29a82a1c4726393cc1c6d0fdcaa83 102 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 94 3.0E-24 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:3.30.70.1430 40 142 3.2E-30 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 625 639 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82714 183 266 1.57E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:3.30.2090.10 183 265 1.1E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:3.30.2090.10 724 809 2.3E-15 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:1.20.1640.10 286 499 4.9E-58 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82866 291 490 3.53E-49 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 809 854 1.2E-8 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 687 722 1.2E-8 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 574 670 2.46E-15 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Pfam PF00873 AcrB/AcrD/AcrF family 6 1030 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 40 133 2.62E-23 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82866 832 1032 1.15E-39 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 136 182 2.43E-20 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82693 268 324 2.43E-20 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:3.30.70.1430 577 666 1.1E-11 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 Gene3D G3DSA:1.10.3850.10 822 1032 5.9E-49 T 06-07-2017 CAL12_RS25095 7d8ad2125fbe601126f085ac7418c354 1053 SUPERFAMILY SSF82714 724 808 1.31E-15 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 SUPERFAMILY SSF88659 98 163 4.49E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 152 4.1E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 Pfam PF04542 Sigma-70 region 2 14 79 2.5E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 Gene3D G3DSA:1.10.10.10 107 153 1.9E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 Gene3D G3DSA:1.10.1740.10 9 92 5.8E-14 T 06-07-2017 CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 SUPERFAMILY SSF88946 9 94 2.16E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11005 2f5c066ea786d507c6fb415f4991921d 173 Pfam PF08281 Sigma-70, region 4 115 158 6.8E-10 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 8.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 6.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 6.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 6.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04640 fd761722026345644cff917adf0fe946 255 SUPERFAMILY SSF51735 11 253 3.97E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04640 fd761722026345644cff917adf0fe946 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 250 4.0E-56 T 06-07-2017 CAL12_RS04640 fd761722026345644cff917adf0fe946 255 Gene3D G3DSA:3.40.50.720 9 252 3.4E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27520 708f100e46d11f6120db928812f5349f 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 7.3E-27 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CAL12_RS27520 708f100e46d11f6120db928812f5349f 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.141 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAL12_RS27520 708f100e46d11f6120db928812f5349f 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 1.0E-36 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAL12_RS27520 708f100e46d11f6120db928812f5349f 72 Gene3D G3DSA:2.40.50.140 1 72 6.9E-38 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27520 708f100e46d11f6120db928812f5349f 72 SUPERFAMILY SSF50249 1 70 4.0E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS06950 ffbb4acb2a01bdafd7ae90f141743a2e 146 Pfam PF03928 Haem-degrading 6 132 3.3E-21 T 06-07-2017 IPR005624 Haem-degrading CAL12_RS06950 ffbb4acb2a01bdafd7ae90f141743a2e 146 SUPERFAMILY SSF143744 6 135 9.55E-28 T 06-07-2017 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Gene3D G3DSA:3.40.50.300 230 413 3.0E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Gene3D G3DSA:1.10.8.60 415 498 2.3E-31 T 06-07-2017 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Pfam PF07724 AAA domain (Cdc48 subfamily) 607 775 1.5E-49 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SMART SM01086 781 872 1.9E-22 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 164 213 4.7E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 85 132 9.7E-9 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SMART SM00382 607 753 7.3E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SMART SM00382 267 414 4.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 674 2.6E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 718 732 2.6E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 685 703 2.6E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 611 629 2.6E-40 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SUPERFAMILY SSF81923 75 214 1.37E-23 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Gene3D G3DSA:1.10.8.60 790 873 2.0E-23 T 06-07-2017 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 781 861 3.5E-20 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 641 659 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Gene3D G3DSA:3.40.50.300 560 789 1.2E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 272 404 5.7E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SUPERFAMILY SSF52540 228 536 1.33E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 365 377 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 SUPERFAMILY SSF52540 556 865 3.4E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13880 7e8e4a9f34768c70d881730a04010723 894 Gene3D G3DSA:1.10.1780.10 74 212 1.7E-34 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 SMART SM00862 159 232 1.3E-16 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 Gene3D G3DSA:1.10.10.10 142 232 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 232 8.3E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 Gene3D G3DSA:3.40.50.2300 12 133 1.8E-36 T 06-07-2017 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 Pfam PF00072 Response regulator receiver domain 15 125 1.6E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 SMART SM00448 13 125 1.3E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 SUPERFAMILY SSF46894 141 233 4.82E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS02720 ed18a48bbb12ed5f9b750595983ccd13 240 SUPERFAMILY SSF52172 8 134 1.05E-37 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.4E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 Gene3D G3DSA:3.40.190.10 191 260 7.4E-11 T 06-07-2017 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 SUPERFAMILY SSF46785 1 109 8.46E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 Gene3D G3DSA:3.40.190.10 83 190 1.3E-17 T 06-07-2017 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 SUPERFAMILY SSF53850 87 290 1.44E-34 T 06-07-2017 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 Gene3D G3DSA:1.10.10.10 1 82 3.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 Pfam PF03466 LysR substrate binding domain 86 286 7.6E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16415 0905a17286d0a39552bab5a7fa6dc056 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 177 1.8E-28 T 06-07-2017 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 PRINTS PR00095 Anthranilate synthase component I signature 429 443 2.7E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 PRINTS PR00095 Anthranilate synthase component I signature 444 458 2.7E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 PRINTS PR00095 Anthranilate synthase component I signature 335 348 2.7E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 PRINTS PR00095 Anthranilate synthase component I signature 349 362 2.7E-22 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 Gene3D G3DSA:3.60.120.10 12 498 3.1E-171 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 Pfam PF00425 chorismate binding enzyme 226 487 1.9E-93 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 495 1.2E-157 T 06-07-2017 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26105 928ff57311596a35b2fbaa28a90e6db0 506 SUPERFAMILY SSF56322 14 495 1.7E-151 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAL12_RS02980 5f55e1c42d47ae5027aace957117a8aa 168 PIRSF PIRSF006162 10 167 4.0E-40 T 06-07-2017 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAL12_RS02980 5f55e1c42d47ae5027aace957117a8aa 168 SUPERFAMILY SSF101307 16 162 4.32E-36 T 06-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CAL12_RS02980 5f55e1c42d47ae5027aace957117a8aa 168 Pfam PF04608 Phosphatidylglycerophosphatase A 21 161 2.6E-47 T 06-07-2017 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CAL12_RS12465 3b0910ae0d662d218224c598aa903fcb 558 SMART SM00244 28 197 2.6E-6 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS12465 3b0910ae0d662d218224c598aa903fcb 558 Pfam PF15975 Flotillin 415 535 3.2E-33 T 06-07-2017 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CAL12_RS12465 3b0910ae0d662d218224c598aa903fcb 558 Pfam PF01145 SPFH domain / Band 7 family 37 186 5.4E-16 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS12465 3b0910ae0d662d218224c598aa903fcb 558 SUPERFAMILY SSF117892 59 201 4.84E-19 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 17 144 1.9E-19 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 Gene3D G3DSA:3.90.470.20 17 143 8.8E-32 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 19 118 2.2E-18 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 16 144 2.9E-27 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 SUPERFAMILY SSF56214 17 143 4.71E-26 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 23 127 2.0E-38 T 06-07-2017 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAL12_RS08875 450eb7e13c007b32b5b64d46bdebc1fa 147 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 18 144 24.395 T 06-07-2017 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 Gene3D G3DSA:3.40.50.300 19 255 2.6E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 235 257 1.5E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 SMART SM00382 44 237 2.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 SUPERFAMILY SSF52540 20 258 1.25E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 Pfam PF00005 ABC transporter 36 187 1.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01720 33310c6fb2f544554d19e87b909ecdf5 262 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 20 262 1.5E-115 T 06-07-2017 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 CAL12_RS21270 243ecc22ff6f283e7f713c2deebb5f86 445 Pfam PF07690 Major Facilitator Superfamily 80 404 1.2E-17 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21270 243ecc22ff6f283e7f713c2deebb5f86 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS21270 243ecc22ff6f283e7f713c2deebb5f86 445 SUPERFAMILY SSF103473 34 434 1.96E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS21270 243ecc22ff6f283e7f713c2deebb5f86 445 Gene3D G3DSA:1.20.1250.20 266 434 8.0E-7 T 06-07-2017 CAL12_RS21270 243ecc22ff6f283e7f713c2deebb5f86 445 Gene3D G3DSA:1.20.1250.20 55 234 5.8E-17 T 06-07-2017 CAL12_RS23470 776115dbc466c49397c2a87481f2774b 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 290 2.8E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23470 776115dbc466c49397c2a87481f2774b 295 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 69 5.5E-7 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS23470 776115dbc466c49397c2a87481f2774b 295 Gene3D G3DSA:1.10.3720.10 84 289 1.2E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23470 776115dbc466c49397c2a87481f2774b 295 SUPERFAMILY SSF161098 87 273 2.09E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Gene3D G3DSA:3.40.50.720 161 438 1.1E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Gene3D G3DSA:3.40.50.10750 573 730 1.9E-49 T 06-07-2017 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 SMART SM01274 18 151 1.7E-77 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 2.1E-26 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 PIRSF PIRSF036684 1 762 0.0 T 06-07-2017 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 SMART SM00919 163 400 2.2E-130 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Pfam PF03949 Malic enzyme, NAD binding domain 165 360 4.5E-20 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 SUPERFAMILY SSF53223 11 161 2.45E-51 T 06-07-2017 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Pfam PF01515 Phosphate acetyl/butaryl transferase 432 755 1.4E-94 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 SUPERFAMILY SSF53659 444 759 6.99E-88 T 06-07-2017 CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 SUPERFAMILY SSF51735 163 436 2.5E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04995 05add388df2ee8f9ac7e571b574db035 762 Gene3D G3DSA:3.40.50.10380 9 160 2.4E-50 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 Gene3D G3DSA:3.40.50.880 292 544 3.1E-97 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 SUPERFAMILY SSF52540 2 270 4.31E-121 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 TIGRFAM TIGR00337 PyrG: CTP synthase 1 538 4.1E-239 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 Pfam PF06418 CTP synthase N-terminus 3 270 1.4E-124 T 06-07-2017 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 Hamap MF_01227 CTP synthase [pyrG]. 2 543 51.023 T 06-07-2017 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 Gene3D G3DSA:3.40.50.300 1 288 6.2E-132 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 SUPERFAMILY SSF52317 292 544 1.15E-85 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS08645 a56be5e54374d8483c7aaefda36bd277 551 Pfam PF00117 Glutamine amidotransferase class-I 305 537 1.7E-56 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS13190 ae5b1501ef3ec2d0a759b9388a070002 348 SUPERFAMILY SSF143865 27 280 4.18E-41 T 06-07-2017 CAL12_RS13190 ae5b1501ef3ec2d0a759b9388a070002 348 Gene3D G3DSA:1.20.58.340 273 346 5.7E-21 T 06-07-2017 CAL12_RS13190 ae5b1501ef3ec2d0a759b9388a070002 348 Pfam PF01544 CorA-like Mg2+ transporter protein 59 344 4.7E-61 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAL12_RS13190 ae5b1501ef3ec2d0a759b9388a070002 348 Gene3D G3DSA:1.20.58.340 166 267 2.1E-12 T 06-07-2017 CAL12_RS13190 ae5b1501ef3ec2d0a759b9388a070002 348 SUPERFAMILY SSF144083 283 345 1.83E-15 T 06-07-2017 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 22 207 2.3E-44 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 Gene3D G3DSA:3.40.50.150 15 215 6.9E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 Gene3D G3DSA:3.90.120.10 262 314 3.3E-6 T 06-07-2017 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 Pfam PF00145 C-5 cytosine-specific DNA methylase 21 326 5.4E-60 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 308 326 - T 06-07-2017 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 20 36 4.1E-16 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 164 177 4.1E-16 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 118 132 4.1E-16 T 06-07-2017 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 80 92 - T 06-07-2017 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CAL12_RS24620 2e9d685404a9fd8ea13fdd46d0e9c945 331 SUPERFAMILY SSF53335 20 328 6.14E-73 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25755 d03a9f9373fcc789b7aebef591880931 305 Pfam PF00005 ABC transporter 64 207 2.0E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25755 d03a9f9373fcc789b7aebef591880931 305 Gene3D G3DSA:3.40.50.300 43 254 3.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25755 d03a9f9373fcc789b7aebef591880931 305 ProSitePatterns PS00211 ABC transporters family signature. 180 194 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS25755 d03a9f9373fcc789b7aebef591880931 305 SUPERFAMILY SSF52540 48 283 2.66E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25755 d03a9f9373fcc789b7aebef591880931 305 SMART SM00382 72 258 1.7E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 ProSitePatterns PS00474 Ribosomal protein L3 signature. 119 142 - T 06-07-2017 IPR019926 Ribosomal protein L3, conserved site CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 SUPERFAMILY SSF50447 13 230 3.71E-79 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 Gene3D G3DSA:4.10.960.10 95 175 9.3E-29 T 06-07-2017 CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 18 222 5.9E-85 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 Pfam PF00297 Ribosomal protein L3 77 200 1.1E-18 T 06-07-2017 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 Gene3D G3DSA:2.40.30.10 176 230 3.3E-8 T 06-07-2017 CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 Gene3D G3DSA:2.40.30.10 18 47 3.3E-8 T 06-07-2017 CAL12_RS27655 0b5fb657c8dde2224250f62c562c3dbc 233 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 16 225 38.575 T 06-07-2017 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 350 2.0E-27 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 Gene3D G3DSA:3.90.650.10 174 354 5.1E-19 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 PIRSF PIRSF036407 12 356 3.4E-117 T 06-07-2017 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 SUPERFAMILY SSF55326 16 170 3.14E-41 T 06-07-2017 CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 TIGRFAM TIGR00476 selD: selenide, water dikinase 16 324 1.2E-131 T 06-07-2017 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 SUPERFAMILY SSF56042 173 352 5.83E-48 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 166 1.3E-20 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 Gene3D G3DSA:3.30.1330.10 37 171 4.5E-33 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS26540 f6769e7f5742665d486ed35739dc7bc9 357 Hamap MF_00625 Selenide, water dikinase [selD]. 14 357 44.326 T 06-07-2017 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 281 1.3E-50 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 SUPERFAMILY SSF51735 98 282 1.77E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 Gene3D G3DSA:3.40.50.720 6 109 4.5E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 Gene3D G3DSA:3.40.50.720 110 284 4.8E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 8 313 1.6E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS04090 8860c51d37eca958b5cf6c558f1a250b 321 SUPERFAMILY SSF52283 29 123 5.29E-20 T 06-07-2017 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 Gene3D G3DSA:1.10.10.10 6 82 4.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 Gene3D G3DSA:3.40.190.10 96 180 9.9E-25 T 06-07-2017 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 Pfam PF03466 LysR substrate binding domain 93 293 1.7E-27 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 2.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 Gene3D G3DSA:3.40.190.10 181 263 1.8E-24 T 06-07-2017 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 SUPERFAMILY SSF53850 91 295 5.97E-32 T 06-07-2017 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05355 cf8f03b97b8ef75af7123634f25393e7 297 SUPERFAMILY SSF46785 5 82 1.02E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01900 b6df714433741654b2e0735812647ccb 445 SUPERFAMILY SSF51735 14 150 4.6E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01900 b6df714433741654b2e0735812647ccb 445 Gene3D G3DSA:3.40.50.720 13 173 2.1E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01900 b6df714433741654b2e0735812647ccb 445 SMART SM00858 361 426 1.4E-5 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS01900 b6df714433741654b2e0735812647ccb 445 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 23 133 7.1E-7 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Gene3D G3DSA:3.40.50.300 170 337 3.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00005 42637403708d556a10305e71bdb083db 509 SUPERFAMILY SSF52540 173 384 2.34E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Gene3D G3DSA:1.10.8.60 339 407 6.8E-27 T 06-07-2017 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 SUPERFAMILY SSF48295 405 508 4.45E-35 T 06-07-2017 IPR010921 Trp repressor/replication initiator GO:0043565 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 418 486 2.5E-31 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 SMART SM00382 205 339 3.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00005 42637403708d556a10305e71bdb083db 509 SMART SM00760 417 486 3.0E-43 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 238 252 4.9E-49 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAL12_RS00005 42637403708d556a10305e71bdb083db 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 270 284 4.9E-49 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAL12_RS00005 42637403708d556a10305e71bdb083db 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 304 331 4.9E-49 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAL12_RS00005 42637403708d556a10305e71bdb083db 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 467 486 4.9E-49 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAL12_RS00005 42637403708d556a10305e71bdb083db 509 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 206 226 4.9E-49 T 06-07-2017 IPR020591 Chromosomal replication control, initiator DnaA-like CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Pfam PF11638 DnaA N-terminal domain 3 66 9.0E-18 T 06-07-2017 IPR024633 DnaA N-terminal domain CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Pfam PF00308 Bacterial dnaA protein 173 390 7.8E-86 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA CAL12_RS00005 42637403708d556a10305e71bdb083db 509 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 507 5.4E-162 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 508 31.504 T 06-07-2017 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 ProSitePatterns PS01008 DnaA protein signature. 467 486 - T 06-07-2017 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CAL12_RS00005 42637403708d556a10305e71bdb083db 509 Gene3D G3DSA:1.10.1750.10 408 508 6.7E-39 T 06-07-2017 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CAL12_RS18905 98d643202cfd6a0295d4f82ddf7bea56 406 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 404 32.786 T 06-07-2017 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 CAL12_RS18905 98d643202cfd6a0295d4f82ddf7bea56 406 Gene3D G3DSA:1.25.40.10 41 166 2.6E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS18905 98d643202cfd6a0295d4f82ddf7bea56 406 SUPERFAMILY SSF48452 40 206 1.47E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 SMART SM00257 425 468 3.8E-15 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 SMART SM00257 332 377 2.0 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Gene3D G3DSA:1.10.530.10 99 261 8.5E-46 T 06-07-2017 CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 SUPERFAMILY SSF53955 103 250 4.5E-41 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Gene3D G3DSA:3.10.350.10 332 377 6.1E-8 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 124 152 - T 06-07-2017 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Pfam PF01476 LysM domain 426 468 1.9E-13 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Pfam PF01476 LysM domain 336 377 1.1E-4 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 SUPERFAMILY SSF54106 424 468 9.68E-11 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Gene3D G3DSA:3.10.350.10 423 469 5.0E-17 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 SUPERFAMILY SSF54106 330 377 2.09E-6 T 06-07-2017 IPR018392 LysM domain CAL12_RS24250 6385d35a540043a64ef9690d17976cb8 474 Pfam PF01464 Transglycosylase SLT domain 107 213 4.4E-24 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.0E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 SUPERFAMILY SSF53850 91 270 4.52E-23 T 06-07-2017 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 Gene3D G3DSA:3.40.190.10 86 187 2.7E-12 T 06-07-2017 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 Pfam PF03466 LysR substrate binding domain 88 268 3.6E-22 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 Gene3D G3DSA:3.40.190.10 188 235 5.4E-9 T 06-07-2017 CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 Gene3D G3DSA:1.10.10.10 1 82 6.1E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00670 2c725cda45999cfec26d2e49296c1cb0 308 SUPERFAMILY SSF46785 3 84 1.47E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 233 1.5E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 SUPERFAMILY SSF88659 80 145 8.63E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PRINTS PR00046 Major sigma-70 factor signature 34 47 2.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PRINTS PR00046 Major sigma-70 factor signature 218 229 2.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PRINTS PR00046 Major sigma-70 factor signature 203 218 2.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PRINTS PR00046 Major sigma-70 factor signature 58 66 2.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PRINTS PR00046 Major sigma-70 factor signature 186 198 2.2E-12 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 SUPERFAMILY SSF88946 8 79 1.57E-21 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Pfam PF04542 Sigma-70 region 2 9 79 6.5E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 9 234 3.5E-78 T 06-07-2017 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 PIRSF PIRSF000770 3 249 4.1E-32 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 1 236 58.97 T 06-07-2017 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Pfam PF04539 Sigma-70 region 3 87 145 4.0E-11 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 SUPERFAMILY SSF88659 163 237 8.04E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Gene3D G3DSA:1.10.601.10 11 77 5.6E-13 T 06-07-2017 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Gene3D G3DSA:1.10.10.10 79 126 1.8E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Pfam PF04545 Sigma-70, region 4 182 231 1.6E-14 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 34 47 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11795 68d34469df4e8a58a5cdf8bea3f88fab 251 Gene3D G3DSA:1.10.10.10 171 235 4.6E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:1.20.1580.10 631 757 4.6E-48 T 06-07-2017 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:1.10.8.280 162 289 7.8E-29 T 06-07-2017 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 SUPERFAMILY SSF52540 543 585 1.29E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 SUPERFAMILY SSF52540 616 850 1.29E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:3.40.50.300 758 873 2.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:3.40.50.300 530 574 2.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:3.40.50.300 610 629 2.7E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:3.40.50.300 405 522 5.0E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:3.40.50.300 19 65 5.0E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 ProSitePatterns PS00211 ABC transporters family signature. 414 428 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 SUPERFAMILY SSF52540 20 101 6.34E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 SUPERFAMILY SSF52540 357 496 6.34E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 SUPERFAMILY SSF52540 155 280 6.34E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:1.20.1580.10 374 404 1.1E-32 T 06-07-2017 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:1.20.1580.10 106 160 1.1E-32 T 06-07-2017 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 Gene3D G3DSA:1.20.1580.10 290 329 1.1E-32 T 06-07-2017 CAL12_RS14025 3c0760c6c3383ce8ed3e02a4394aa41e 889 ProSitePatterns PS00211 ABC transporters family signature. 767 781 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS09145 3c7e44bf167749a9ce71360f326d7191 435 Pfam PF06864 Pilin accessory protein (PilO) 28 139 7.9E-7 T 06-07-2017 IPR009663 Pilin accessory predicted CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 SUPERFAMILY SSF46785 2 83 7.07E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 Gene3D G3DSA:3.40.190.10 92 178 2.9E-16 T 06-07-2017 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 SUPERFAMILY SSF53850 93 295 9.01E-37 T 06-07-2017 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 Gene3D G3DSA:1.10.10.10 3 88 4.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 Pfam PF03466 LysR substrate binding domain 93 291 1.2E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 3.5E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14005 d2a80720a546b856bf6474c31eecc088 297 Gene3D G3DSA:3.40.190.10 179 263 3.7E-22 T 06-07-2017 CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 Pfam PF13458 Periplasmic binding protein 30 372 1.7E-58 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 Gene3D G3DSA:3.40.50.2300 30 231 1.5E-62 T 06-07-2017 CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 SUPERFAMILY SSF53822 30 377 1.73E-90 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 5.8E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 261 279 5.8E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS17360 bfb9c49dc087585ce2ecfc6d993575c3 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 96 106 5.8E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 341 4.2E-157 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 SMART SM00861 362 545 9.2E-66 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Pfam PF02779 Transketolase, pyrimidine binding domain 361 544 1.3E-43 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 SUPERFAMILY SSF52518 342 546 1.5E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Gene3D G3DSA:3.40.50.970 10 326 7.1E-126 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Gene3D G3DSA:3.40.50.970 334 552 4.1E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 SUPERFAMILY SSF52518 11 335 1.32E-115 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 SUPERFAMILY SSF52922 555 681 8.77E-43 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Gene3D G3DSA:3.40.50.920 558 681 1.9E-46 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 680 4.5E-280 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CAL12_RS05010 4e29ca883228efe56117910a4cab2eb1 681 Pfam PF02780 Transketolase, C-terminal domain 560 673 3.7E-15 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAL12_RS23830 22a01a45488bdca1618b6b7d0f8249a4 220 Pfam PF01966 HD domain 29 132 1.1E-13 T 06-07-2017 IPR006674 HD domain CAL12_RS23830 22a01a45488bdca1618b6b7d0f8249a4 220 Gene3D G3DSA:1.10.3210.10 22 146 5.3E-37 T 06-07-2017 IPR006674 HD domain CAL12_RS23830 22a01a45488bdca1618b6b7d0f8249a4 220 Gene3D G3DSA:1.10.3210.10 185 215 5.3E-37 T 06-07-2017 IPR006674 HD domain CAL12_RS23830 22a01a45488bdca1618b6b7d0f8249a4 220 SMART SM00471 24 142 2.5E-9 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS23830 22a01a45488bdca1618b6b7d0f8249a4 220 SUPERFAMILY SSF109604 14 215 4.28E-58 T 06-07-2017 CAL12_RS13920 97bbd0fb9c50ca0fdc9a1038c9c54edd 404 Gene3D G3DSA:1.20.1250.20 24 207 1.6E-29 T 06-07-2017 CAL12_RS13920 97bbd0fb9c50ca0fdc9a1038c9c54edd 404 Gene3D G3DSA:1.20.1250.20 221 397 6.7E-7 T 06-07-2017 CAL12_RS13920 97bbd0fb9c50ca0fdc9a1038c9c54edd 404 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 23 398 5.4E-80 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAL12_RS13920 97bbd0fb9c50ca0fdc9a1038c9c54edd 404 SUPERFAMILY SSF103473 6 395 8.11E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13920 97bbd0fb9c50ca0fdc9a1038c9c54edd 404 Pfam PF07690 Major Facilitator Superfamily 28 365 2.0E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 SMART SM00100 40 160 6.6E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 SUPERFAMILY SSF46785 174 249 1.42E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 Pfam PF13545 Crp-like helix-turn-helix domain 177 249 2.8E-20 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 202 218 2.8E-10 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 218 233 2.8E-10 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 Gene3D G3DSA:2.60.120.10 59 178 2.8E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 SUPERFAMILY SSF51206 58 170 1.57E-20 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 Pfam PF00027 Cyclic nucleotide-binding domain 59 143 1.4E-12 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 Gene3D G3DSA:1.10.10.10 179 249 4.3E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15180 b107f17d6eb9fa079a7009f0f2dd05d4 251 SMART SM00419 196 244 1.0E-13 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 Pfam PF13545 Crp-like helix-turn-helix domain 151 222 5.7E-11 T 06-07-2017 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 Gene3D G3DSA:2.60.120.10 12 141 3.0E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 SMART SM00100 13 131 7.3E-7 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 SUPERFAMILY SSF46785 148 222 2.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 1.4E-13 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 Gene3D G3DSA:1.10.10.10 148 222 1.1E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26440 71a9236a6cf528afb26e4b7d36c0d377 228 SUPERFAMILY SSF51206 12 140 1.02E-24 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Pfam PF00072 Response regulator receiver domain 410 522 1.8E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Gene3D G3DSA:3.40.50.2300 407 526 5.0E-33 T 06-07-2017 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SUPERFAMILY SSF47384 146 222 1.0E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 26 146 3.9E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 222 3.6E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SUPERFAMILY SSF52172 409 526 9.68E-27 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SMART SM00448 408 521 3.7E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 346 2.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 318 332 2.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 349 367 2.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 386 2.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SMART SM00091 22 91 4.7E-6 T 06-07-2017 IPR000014 PAS domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 269 388 7.8E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Gene3D G3DSA:3.30.450.20 35 139 2.2E-35 T 06-07-2017 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SMART SM00086 97 139 1.4E-9 T 06-07-2017 IPR001610 PAC motif CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Pfam PF13426 PAS domain 42 137 2.8E-20 T 06-07-2017 IPR000014 PAS domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SUPERFAMILY SSF55874 214 387 2.1E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Gene3D G3DSA:3.30.565.10 211 390 4.4E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SMART SM00388 154 224 2.9E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SUPERFAMILY SSF55785 31 139 1.54E-28 T 06-07-2017 IPR000014 PAS domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 SMART SM00387 264 389 6.0E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14695 6022192279edeb1ce1650100cc05a7f6 532 Gene3D G3DSA:1.10.287.130 147 210 4.4E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.2E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.2E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.2E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.2E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.2E-11 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 SUPERFAMILY SSF52540 7 273 8.81E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 SUPERFAMILY SSF54980 388 459 2.45E-16 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 SUPERFAMILY SSF50447 257 387 3.3E-26 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Pfam PF16658 Class II release factor RF3, C-terminal domain 383 511 9.1E-44 T 06-07-2017 IPR032090 Peptide chain release factor 3, C-terminal CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 145 8.5E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 526 2.6E-212 T 06-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Pfam PF00009 Elongation factor Tu GTP binding domain 10 273 7.0E-53 T 06-07-2017 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Gene3D G3DSA:3.40.50.300 4 278 7.5E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Gene3D G3DSA:2.40.30.10 288 387 9.7E-20 T 06-07-2017 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Gene3D G3DSA:3.30.70.870 391 460 2.9E-15 T 06-07-2017 CAL12_RS00690 06d1ff9076f1734028e1c3c472eadb54 537 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 524 50.859 T 06-07-2017 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Pfam PF00072 Response regulator receiver domain 929 1038 2.7E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SUPERFAMILY SSF47384 667 748 6.08E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SMART SM00448 927 1038 1.5E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Gene3D G3DSA:1.10.287.130 674 743 3.6E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SMART SM00388 681 747 2.4E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Gene3D G3DSA:3.30.565.10 748 905 5.1E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SUPERFAMILY SSF52172 926 1050 4.41E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SUPERFAMILY SSF55874 737 901 8.38E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 SMART SM00387 794 905 7.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 PRINTS PR00344 Bacterial sensor protein C-terminal signature 830 844 2.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 PRINTS PR00344 Bacterial sensor protein C-terminal signature 889 902 2.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 PRINTS PR00344 Bacterial sensor protein C-terminal signature 848 858 2.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 PRINTS PR00344 Bacterial sensor protein C-terminal signature 865 883 2.2E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Gene3D G3DSA:3.40.50.2300 926 1049 1.1E-33 T 06-07-2017 CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 795 902 8.1E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03785 9158dce3d65534b578395eab44f75846 1136 Pfam PF00512 His Kinase A (phospho-acceptor) domain 681 747 1.8E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 6.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 Pfam PF00106 short chain dehydrogenase 13 194 2.0E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 Gene3D G3DSA:3.40.50.720 6 233 4.0E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22970 1611fc382e17139f25467c8cd8f0f402 242 SUPERFAMILY SSF51735 8 228 7.89E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 SUPERFAMILY SSF50249 1 67 2.1E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.1E-29 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 PRINTS PR00050 Cold shock protein signature 40 58 3.8E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 PRINTS PR00050 Cold shock protein signature 25 34 3.8E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 PRINTS PR00050 Cold shock protein signature 4 19 3.8E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 Gene3D G3DSA:2.40.50.140 1 66 1.3E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 SMART SM00357 3 67 5.9E-29 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS17230 9ba470a248e97b968035d0c57ed64a44 68 PIRSF PIRSF002599 1 68 6.7E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS08585 835fd0d9c9bab729e023333f3c536e17 254 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 14 245 1.0E-19 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS08585 835fd0d9c9bab729e023333f3c536e17 254 SUPERFAMILY SSF56219 8 251 1.44E-50 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS08585 835fd0d9c9bab729e023333f3c536e17 254 Gene3D G3DSA:3.60.10.10 7 251 1.3E-14 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 Pfam PF00210 Ferritin-like domain 42 175 7.4E-28 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 Gene3D G3DSA:1.20.1260.10 19 176 2.1E-55 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 157 175 8.6E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 8.6E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 85 101 8.6E-9 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 SUPERFAMILY SSF47240 25 178 3.69E-47 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS23080 19b39c87fa5901b3efe81f94ed24fde0 187 PIRSF PIRSF005900 18 184 4.1E-48 T 06-07-2017 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 Gene3D G3DSA:3.40.190.10 92 175 6.6E-18 T 06-07-2017 CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 Gene3D G3DSA:1.10.10.10 2 84 1.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 Gene3D G3DSA:3.40.190.10 176 267 1.4E-15 T 06-07-2017 CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 SUPERFAMILY SSF53850 92 292 1.09E-38 T 06-07-2017 CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 SUPERFAMILY SSF46785 2 85 3.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.5E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19420 9607d1a261cf6f34f3e66751113e36cd 293 Pfam PF03466 LysR substrate binding domain 92 292 6.9E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 SUPERFAMILY SSF53850 101 301 4.52E-26 T 06-07-2017 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 3.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Gene3D G3DSA:1.10.10.10 8 90 1.3E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 SUPERFAMILY SSF46785 11 90 1.11E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 9.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 9.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 9.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Gene3D G3DSA:3.40.190.10 179 274 1.3E-15 T 06-07-2017 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Gene3D G3DSA:3.40.190.10 101 178 3.2E-13 T 06-07-2017 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Gene3D G3DSA:3.40.190.10 278 304 3.2E-13 T 06-07-2017 CAL12_RS21055 1a572008905a6adb0855f516008fabb1 310 Pfam PF03466 LysR substrate binding domain 105 303 2.0E-17 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 213 238 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 127 144 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 65 87 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 88 106 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 145 167 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 196 212 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 PRINTS PR01003 Flagellar assembly protein FliH signature 168 195 2.5E-20 T 06-07-2017 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 CAL12_RS12015 e18ae822c31b02476366cb4519e41486 245 Pfam PF02108 Flagellar assembly protein FliH 105 231 1.8E-36 T 06-07-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 Pfam PF00005 ABC transporter 17 166 2.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 Gene3D G3DSA:3.40.50.300 1 232 1.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 SMART SM00382 26 217 8.6E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 SUPERFAMILY SSF52540 2 237 5.21E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 237 5.3E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS26450 6ff162a18fde5298b97bb94bf3638d84 240 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10430 83ba2238f6acfbd753dc7181e48b8db6 265 SUPERFAMILY SSF161098 6 258 1.12E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10430 83ba2238f6acfbd753dc7181e48b8db6 265 Gene3D G3DSA:1.10.3720.10 13 258 1.1E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10430 83ba2238f6acfbd753dc7181e48b8db6 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 253 3.0E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 SMART SM00342 220 303 4.5E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 Gene3D G3DSA:1.10.10.60 257 307 8.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 SMART SM00448 66 178 2.1E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 SUPERFAMILY SSF46689 257 307 8.36E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 Gene3D G3DSA:1.10.10.60 206 251 8.8E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 Pfam PF12833 Helix-turn-helix domain 226 305 4.6E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 SUPERFAMILY SSF52172 61 192 1.42E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 Pfam PF00072 Response regulator receiver domain 68 178 4.6E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22160 aa6ca07bd52c8d643a1d19052b2a1ed2 316 Gene3D G3DSA:3.40.50.2300 63 189 4.4E-23 T 06-07-2017 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 Gene3D G3DSA:3.30.1490.10 75 130 3.2E-28 T 06-07-2017 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 Pfam PF00410 Ribosomal protein S8 5 130 2.1E-50 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 Gene3D G3DSA:3.30.1370.30 2 72 9.5E-29 T 06-07-2017 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 SUPERFAMILY SSF56047 2 130 6.02E-48 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27555 a09af91f3227f266581c7570416a3304 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.597 T 06-07-2017 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 SUPERFAMILY SSF52540 87 323 4.47E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 Pfam PF01883 Domain of unknown function DUF59 6 68 2.5E-10 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 Gene3D G3DSA:3.40.50.300 91 338 7.6E-105 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 339 36.958 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 ProSitePatterns PS01215 Mrp family signature. 202 218 - T 06-07-2017 IPR000808 Mrp, conserved site GO:0005524 CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 338 2.5E-101 T 06-07-2017 IPR019591 Mrp/NBP35 ATP-binding protein CAL12_RS02605 a6488a4865e4b7cdee23edbd63791db2 361 SUPERFAMILY SSF117916 5 84 1.08E-7 T 06-07-2017 CAL12_RS02435 52c7be72320d927354d1e9a22a0c9732 300 SUPERFAMILY SSF161098 96 281 5.36E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02435 52c7be72320d927354d1e9a22a0c9732 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 297 2.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02435 52c7be72320d927354d1e9a22a0c9732 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 64 3.4E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS02435 52c7be72320d927354d1e9a22a0c9732 300 Gene3D G3DSA:1.10.3720.10 94 296 7.4E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24330 7b44a95c2014b7cab2a44d964912bc23 443 Pfam PF01425 Amidase 24 416 9.0E-71 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24330 7b44a95c2014b7cab2a44d964912bc23 443 Gene3D G3DSA:3.90.1300.10 5 423 8.4E-114 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24330 7b44a95c2014b7cab2a44d964912bc23 443 SUPERFAMILY SSF75304 2 422 9.94E-107 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Pfam PF12951 Passenger-associated-transport-repeat 73 100 6.2E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Pfam PF12951 Passenger-associated-transport-repeat 138 166 4.4E-4 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Pfam PF12951 Passenger-associated-transport-repeat 7 35 3.5E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 6 35 5.8E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 136 167 6.9E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 73 100 6.4E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Gene3D G3DSA:2.160.20.20 2 102 9.9E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 SMART SM00869 422 690 4.0E-53 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 211 700 1.2E-41 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 SUPERFAMILY SSF51126 2 280 5.02E-21 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Gene3D G3DSA:2.40.128.130 397 700 4.4E-66 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 Pfam PF03797 Autotransporter beta-domain 422 685 1.8E-61 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 SUPERFAMILY SSF103515 360 387 2.22E-66 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23615 a359c79f412fbbdfa2d8c56709e9487d 700 SUPERFAMILY SSF103515 418 700 2.22E-66 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 607 629 4.7E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 Pfam PF00005 ABC transporter 399 558 1.2E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 Pfam PF02653 Branched-chain amino acid transport system / permease component 78 337 4.9E-33 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 SUPERFAMILY SSF52540 383 628 1.21E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 Gene3D G3DSA:3.40.50.300 381 625 6.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00365 472e568a6fe9a3a142dce15f6ef04769 630 SMART SM00382 407 615 2.8E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 Gene3D G3DSA:2.40.10.240 83 153 5.2E-12 T 06-07-2017 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 Gene3D G3DSA:3.40.1780.10 22 81 5.9E-99 T 06-07-2017 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 Gene3D G3DSA:3.40.1780.10 194 356 5.9E-99 T 06-07-2017 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 21 357 45.529 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 22 356 1.1E-127 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 SUPERFAMILY SSF111337 22 356 3.92E-131 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAL12_RS04935 38014e0b17a804dd15de3497e943cab0 364 Pfam PF02547 Queuosine biosynthesis protein 23 356 1.8E-132 T 06-07-2017 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 Gene3D G3DSA:3.90.76.10 29 170 1.2E-28 T 06-07-2017 CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 Gene3D G3DSA:3.40.190.10 171 279 8.2E-28 T 06-07-2017 CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 50 411 2.1E-76 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 SUPERFAMILY SSF53850 15 506 8.51E-107 T 06-07-2017 CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 PIRSF PIRSF002741 33 501 1.4E-70 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS24295 af1d77eac6f2f5cc86404c5a1f377a52 508 Gene3D G3DSA:3.10.105.10 280 477 1.0E-40 T 06-07-2017 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 137 6.6E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.90.1170.50 12 126 2.7E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 153 720 2.4E-153 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 461 610 3.9E-44 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 373 460 2.9E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 635 785 2.9E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 SUPERFAMILY SSF54665 12 141 3.27E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 289 366 2.8E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 127 181 2.8E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 SUPERFAMILY SSF56003 129 784 1.57E-178 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 SMART SM01008 28 137 1.0E-23 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS12865 924359bb6e409828ec264c9143ad39b2 798 Gene3D G3DSA:3.30.365.10 182 287 8.1E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS06280 5d97d89a8b8a6b21f647784f33809750 234 SUPERFAMILY SSF53448 1 225 3.6E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS06280 5d97d89a8b8a6b21f647784f33809750 234 Gene3D G3DSA:3.90.550.10 1 230 9.1E-49 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS06280 5d97d89a8b8a6b21f647784f33809750 234 Pfam PF00483 Nucleotidyl transferase 3 140 9.2E-19 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAL12_RS03170 42d82ee3671733bda6965c5192de4dc8 324 SUPERFAMILY SSF161098 95 308 6.15E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03170 42d82ee3671733bda6965c5192de4dc8 324 Gene3D G3DSA:1.10.3720.10 93 315 1.5E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03170 42d82ee3671733bda6965c5192de4dc8 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 322 3.3E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07380 5966bafa90047423f5329563f93356a7 283 Pfam PF04228 Putative neutral zinc metallopeptidase 1 278 3.1E-119 T 06-07-2017 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 Gene3D G3DSA:3.20.20.10 17 225 1.8E-42 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 SMART SM01005 245 370 9.8E-48 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 Pfam PF00842 Alanine racemase, C-terminal domain 245 367 6.2E-31 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 Pfam PF01168 Alanine racemase, N-terminal domain 14 231 1.3E-43 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 Gene3D G3DSA:2.40.37.10 226 368 1.5E-46 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 Hamap MF_01201 Alanine racemase. 7 370 26.236 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 SUPERFAMILY SSF50621 240 368 1.43E-38 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 TIGRFAM TIGR00492 alr: alanine racemase 11 368 4.6E-74 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 40 50 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 SUPERFAMILY SSF51419 14 246 1.76E-41 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 69 87 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 204 231 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 352 365 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 299 316 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 278 293 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 35 51 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 261 276 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS14980 e0566bc2b9901795b45615abf4589c89 381 PRINTS PR00992 Alanine racemase signature 167 178 8.2E-42 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 Gene3D G3DSA:3.40.190.10 180 262 1.2E-15 T 06-07-2017 CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 Gene3D G3DSA:3.40.190.10 95 179 2.5E-15 T 06-07-2017 CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 Pfam PF03466 LysR substrate binding domain 91 295 1.5E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 Gene3D G3DSA:1.10.10.10 5 89 5.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 SUPERFAMILY SSF53850 92 295 3.08E-36 T 06-07-2017 CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 SUPERFAMILY SSF46785 6 90 1.89E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16470 7bcf484b422a046346d551bbb4645547 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 2.2E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 SUPERFAMILY SSF51621 170 344 3.45E-92 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 SUPERFAMILY SSF51621 3 78 3.45E-92 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Gene3D G3DSA:3.20.20.60 5 75 1.5E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Gene3D G3DSA:3.20.20.60 172 330 1.5E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 476 2.8E-24 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 477 3.0E-161 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 SUPERFAMILY SSF50800 73 168 6.63E-26 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 249 273 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 318 334 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 222 248 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 299 317 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 189 203 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 PRINTS PR01050 Pyruvate kinase family signature 274 298 1.3E-50 T 06-07-2017 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 SUPERFAMILY SSF52935 328 479 2.22E-35 T 06-07-2017 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Pfam PF00224 Pyruvate kinase, barrel domain 5 343 3.1E-124 T 06-07-2017 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 06-07-2017 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Gene3D G3DSA:2.40.33.10 76 171 8.0E-29 T 06-07-2017 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS06310 3250cd4695a688f01a717d058af78174 480 Gene3D G3DSA:3.40.1380.20 331 479 2.9E-34 T 06-07-2017 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Pfam PF01568 Molydopterin dinucleotide binding domain 690 760 3.0E-6 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 SUPERFAMILY SSF54292 1 74 3.77E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Gene3D G3DSA:3.40.50.740 273 345 2.0E-41 T 06-07-2017 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Gene3D G3DSA:3.40.50.740 483 651 2.0E-41 T 06-07-2017 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Gene3D G3DSA:3.10.20.30 3 60 4.1E-6 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 119 2.4E-16 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Pfam PF00384 Molybdopterin oxidoreductase 524 631 5.9E-10 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Pfam PF00384 Molybdopterin oxidoreductase 273 411 4.1E-17 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 76 5.0E-20 T 06-07-2017 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 SUPERFAMILY SSF53706 214 654 2.22E-82 T 06-07-2017 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 06-07-2017 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 SUPERFAMILY SSF54862 75 211 3.39E-35 T 06-07-2017 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 SMART SM00929 83 123 2.9E-20 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19680 5776931e79d3ab41c9fddd34e4b6d4ae 775 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 630 2.9E-198 T 06-07-2017 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS15385 40beeba99865dfc5e53ef93386eee6cf 384 Pfam PF01882 Protein of unknown function DUF58 74 158 3.1E-21 T 06-07-2017 IPR002881 Domain of unknown function DUF58 CAL12_RS15385 40beeba99865dfc5e53ef93386eee6cf 384 SUPERFAMILY SSF53300 113 234 1.11E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 Gene3D G3DSA:3.40.920.10 746 945 3.9E-14 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 479 563 1.5E-6 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 Gene3D G3DSA:3.40.50.970 512 669 3.9E-11 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 752 939 6.0E-21 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 SUPERFAMILY SSF52518 459 642 4.34E-14 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 Gene3D G3DSA:3.40.50.970 111 228 1.8E-4 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 SUPERFAMILY SSF52518 58 240 1.77E-20 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS25275 c50b7a80ca4027161e61a39167e86bc1 1241 SUPERFAMILY SSF53323 744 954 4.71E-30 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAL12_RS18395 a9620f96cd3f4b08e2a6a32a03c873da 230 Hamap MF_01385 Urease accessory protein UreF [ureF]. 10 230 30.922 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAL12_RS18395 a9620f96cd3f4b08e2a6a32a03c873da 230 PIRSF PIRSF009467 7 230 3.8E-64 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAL12_RS18395 a9620f96cd3f4b08e2a6a32a03c873da 230 Pfam PF01730 UreF 42 188 3.9E-37 T 06-07-2017 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Pfam PF00330 Aconitase family (aconitate hydratase) 10 461 1.2E-134 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 470 51.351 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 290 304 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 137 152 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 199 212 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 403 416 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 123 136 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 347 358 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 112 120 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 PRINTS PR00415 Aconitase family signature 213 226 4.5E-42 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Gene3D G3DSA:3.30.499.10 339 469 1.2E-59 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Gene3D G3DSA:3.30.499.10 297 307 1.2E-59 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Gene3D G3DSA:3.40.1060.10 170 284 1.5E-30 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 SUPERFAMILY SSF53732 3 470 4.05E-151 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 ProSitePatterns PS00450 Aconitase family signature 1. 343 359 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 ProSitePatterns PS01244 Aconitase family signature 2. 403 416 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 469 2.8E-183 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS26645 98618676d11f76ea73cf61328459f17b 475 Gene3D G3DSA:3.30.499.10 11 163 2.0E-22 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 Pfam PF07690 Major Facilitator Superfamily 28 419 1.8E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 Gene3D G3DSA:1.20.1250.20 487 512 4.7E-19 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 Gene3D G3DSA:1.20.1250.20 267 430 4.7E-19 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 Gene3D G3DSA:1.20.1250.20 24 206 7.1E-31 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 2.1E-8 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 2.1E-8 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 2.1E-8 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 PRINTS PR01036 Tetracycline resistance protein TetB signature 410 429 2.1E-8 T 06-07-2017 CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 SUPERFAMILY SSF103473 486 515 2.88E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 SUPERFAMILY SSF103473 257 429 2.88E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS27215 51840e58d8640f9926114dd5d6ce54dc 531 SUPERFAMILY SSF103473 8 206 2.88E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 SUPERFAMILY SSF52172 1 176 1.43E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 SMART SM00862 145 216 5.6E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 Gene3D G3DSA:1.10.10.10 124 216 1.5E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 SMART SM00448 1 112 1.3E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 Pfam PF00072 Response regulator receiver domain 3 112 1.7E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.6E-19 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS14250 5910c32623e79eb3cba59be9926e8d4f 223 Gene3D G3DSA:3.40.50.2300 1 123 3.7E-34 T 06-07-2017 CAL12_RS26090 9baf9d6dd291b2d1b23497c98b08d5f9 124 Pfam PF04379 Protein of unknown function (DUF525) 17 101 4.3E-37 T 06-07-2017 IPR007474 ApaG domain CAL12_RS26090 9baf9d6dd291b2d1b23497c98b08d5f9 124 SUPERFAMILY SSF110069 5 124 1.96E-48 T 06-07-2017 IPR007474 ApaG domain CAL12_RS26090 9baf9d6dd291b2d1b23497c98b08d5f9 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.644 T 06-07-2017 IPR023065 Uncharacterised protein family ApaG CAL12_RS26090 9baf9d6dd291b2d1b23497c98b08d5f9 124 Gene3D G3DSA:2.60.40.1470 6 124 2.9E-47 T 06-07-2017 IPR007474 ApaG domain CAL12_RS26370 c88d63fc9c9cde707dade82fcb1fb379 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 125 6.0E-14 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS26370 c88d63fc9c9cde707dade82fcb1fb379 208 SUPERFAMILY SSF50475 34 154 2.69E-21 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS26370 c88d63fc9c9cde707dade82fcb1fb379 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 1.6E-80 T 06-07-2017 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CAL12_RS26370 c88d63fc9c9cde707dade82fcb1fb379 208 Gene3D G3DSA:2.30.110.10 30 151 4.3E-23 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 Gene3D G3DSA:3.50.50.60 8 261 3.4E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 Gene3D G3DSA:3.50.50.60 433 495 3.4E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 Pfam PF00890 FAD binding domain 9 475 3.0E-49 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 SUPERFAMILY SSF51905 436 496 1.15E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 SUPERFAMILY SSF51905 8 279 1.15E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 Gene3D G3DSA:3.90.700.10 292 428 4.4E-21 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS13620 00eff0df362d8645499e0b388dd14c4c 500 SUPERFAMILY SSF56425 294 437 3.42E-25 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 Gene3D G3DSA:2.40.50.140 16 79 2.2E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 39 48 3.1E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 54 72 3.1E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 18 33 3.1E-17 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 PIRSF PIRSF002599 12 81 5.2E-24 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 SMART SM00357 17 81 2.3E-32 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 ProSitePatterns PS00352 'Cold-shock' domain signature. 29 48 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 Pfam PF00313 'Cold-shock' DNA-binding domain 17 80 3.0E-31 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17405 df0e3e94b55d12014c0c9be2fb3a54d5 81 SUPERFAMILY SSF50249 15 79 2.36E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 248 261 1.8E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 171 182 1.8E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 221 238 1.8E-12 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 Gene3D G3DSA:3.40.710.10 137 382 2.2E-66 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 136 364 2.5E-54 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAL12_RS06445 cf7493d1ccbfe3179edb51f9d04bb31c 388 SUPERFAMILY SSF56601 128 381 4.95E-58 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 276 283 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 Pfam PF00171 Aldehyde dehydrogenase family 33 501 2.3E-177 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 304 315 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 Gene3D G3DSA:3.40.309.10 290 476 3.8E-69 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 Gene3D G3DSA:3.40.605.10 24 289 7.1E-107 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS19760 7cee42e3755904e551940e9190abea24 506 SUPERFAMILY SSF53720 20 504 1.44E-173 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Pfam PF00563 EAL domain 25 258 1.2E-44 T 06-07-2017 IPR001633 EAL domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Gene3D G3DSA:3.20.20.450 24 259 8.3E-45 T 06-07-2017 IPR001633 EAL domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Gene3D G3DSA:3.30.70.270 429 591 7.5E-20 T 06-07-2017 CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 SUPERFAMILY SSF54631 303 427 5.5E-8 T 06-07-2017 CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 SUPERFAMILY SSF141868 23 259 1.24E-50 T 06-07-2017 IPR001633 EAL domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 SMART SM00052 16 263 3.8E-19 T 06-07-2017 IPR001633 EAL domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Gene3D G3DSA:3.10.580.10 306 417 1.1E-7 T 06-07-2017 CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Pfam PF00990 Diguanylate cyclase, GGDEF domain 454 523 1.8E-10 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 SUPERFAMILY SSF55073 431 594 1.26E-19 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 Pfam PF00571 CBS domain 307 343 1.3E-5 T 06-07-2017 IPR000644 CBS domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 SMART SM00267 414 579 5.8E-5 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS15335 53d93cd24cd1685932fde7e45e91a1e9 609 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 459 518 3.0E-10 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 PIRSF PIRSF039085 2 245 4.0E-107 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 Gene3D G3DSA:3.40.50.300 4 240 1.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 SMART SM00382 30 217 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 Pfam PF00005 ABC transporter 21 169 1.9E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24140 86ac2845aa204c06de18668755b3e88d 256 SUPERFAMILY SSF52540 5 239 4.83E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Gene3D G3DSA:3.40.120.10 178 254 1.7E-11 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Gene3D G3DSA:3.30.310.50 374 463 5.9E-17 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 SUPERFAMILY SSF53738 161 259 1.53E-13 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Gene3D G3DSA:3.40.120.10 16 142 1.2E-23 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 SUPERFAMILY SSF55957 372 466 3.66E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 SUPERFAMILY SSF53738 13 135 1.37E-26 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 258 3.2E-11 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Gene3D G3DSA:3.40.120.10 256 371 3.6E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 SUPERFAMILY SSF53738 263 360 3.81E-24 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 16 143 2.7E-24 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS08025 09fd23416cfe8f5c583f75f97152867e 466 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 369 6.8E-16 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 Gene3D G3DSA:3.40.190.10 88 175 2.8E-26 T 06-07-2017 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 Gene3D G3DSA:3.40.190.10 176 270 2.4E-28 T 06-07-2017 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.1E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 Gene3D G3DSA:1.10.10.10 1 84 4.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 Pfam PF03466 LysR substrate binding domain 87 294 8.5E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 SUPERFAMILY SSF53850 87 294 4.1E-32 T 06-07-2017 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.9E-25 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12405 85ba2f84b816e6c8a69b29c6a64b509e 297 SUPERFAMILY SSF46785 1 84 6.47E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 Pfam PF02913 FAD linked oxidases, C-terminal domain 235 472 2.2E-67 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 SUPERFAMILY SSF55103 206 475 2.78E-72 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 SUPERFAMILY SSF56176 20 232 2.34E-67 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 Gene3D G3DSA:3.30.43.10 14 111 9.0E-27 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 Pfam PF01565 FAD binding domain 57 196 4.0E-39 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 Gene3D G3DSA:1.10.45.10 433 472 9.5E-7 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS17770 f27be6e12ae6c6b3e54a208b0bd51f3d 500 Gene3D G3DSA:3.30.465.10 113 232 9.7E-33 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 SUPERFAMILY SSF51604 95 359 6.42E-81 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 SUPERFAMILY SSF54826 1 112 1.21E-31 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 3.3E-27 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 Gene3D G3DSA:3.20.20.120 118 344 1.3E-86 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 Pfam PF13378 Enolase C-terminal domain-like 130 355 1.0E-62 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 SMART SM00922 125 230 9.4E-25 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS02220 ba43bb2f00d4715edc48d7fa5fc72d5c 382 Gene3D G3DSA:3.30.390.10 1 117 1.6E-53 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS24020 de68c1ec81e9e2163b8c73533b029cab 289 SUPERFAMILY SSF88713 11 280 4.0E-53 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS24020 de68c1ec81e9e2163b8c73533b029cab 289 Pfam PF04794 YdjC-like protein 12 269 6.7E-45 T 06-07-2017 IPR006879 Chitooligosaccharide deacetylase ChbG-like CAL12_RS24020 de68c1ec81e9e2163b8c73533b029cab 289 Gene3D G3DSA:3.20.20.370 10 281 3.1E-52 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 SUPERFAMILY SSF53850 86 286 2.93E-35 T 06-07-2017 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 Gene3D G3DSA:3.40.190.10 187 251 4.0E-14 T 06-07-2017 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 Gene3D G3DSA:1.10.10.10 2 79 9.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 7.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 7.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 7.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.1E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 Pfam PF03466 LysR substrate binding domain 84 285 2.7E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 SUPERFAMILY SSF46785 5 107 2.73E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25615 35c1320ad9681494ec0e3e4a4a34b946 287 Gene3D G3DSA:3.40.190.10 86 186 1.3E-22 T 06-07-2017 CAL12_RS06030 4738e3070bc1742557b544700e1d8c36 347 PIRSF PIRSF017082 20 347 4.7E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06030 4738e3070bc1742557b544700e1d8c36 347 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 71 343 1.8E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06030 4738e3070bc1742557b544700e1d8c36 347 SUPERFAMILY SSF53850 134 310 1.25E-10 T 06-07-2017 CAL12_RS04745 c8cfda7a8fca253a015b3737e54fe0d2 225 SUPERFAMILY SSF56784 4 210 1.44E-12 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS04745 c8cfda7a8fca253a015b3737e54fe0d2 225 Gene3D G3DSA:3.40.50.1000 70 213 8.6E-61 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 SUPERFAMILY SSF46894 4 66 3.2E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 Pfam PF00196 Bacterial regulatory proteins, luxR family 5 59 2.6E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 20 36 5.6E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 6 20 5.6E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 36 48 5.6E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 SMART SM00421 3 60 1.8E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25365 4feb0088df4334cf792865c6d8cfe904 76 Gene3D G3DSA:1.10.10.10 5 65 6.7E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16520 776ea3947edf5a7a339e48a3061a589f 275 Gene3D G3DSA:1.20.950.20 7 42 5.7E-50 T 06-07-2017 CAL12_RS16520 776ea3947edf5a7a339e48a3061a589f 275 Gene3D G3DSA:1.20.950.20 102 266 5.7E-50 T 06-07-2017 CAL12_RS16520 776ea3947edf5a7a339e48a3061a589f 275 SUPERFAMILY SSF81342 8 58 7.36E-35 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS16520 776ea3947edf5a7a339e48a3061a589f 275 SUPERFAMILY SSF81342 116 266 7.36E-35 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS16520 776ea3947edf5a7a339e48a3061a589f 275 Pfam PF01292 Prokaryotic cytochrome b561 11 264 3.8E-39 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS09250 7b8208d3fc5a94a29898f033b8c096be 78 SUPERFAMILY SSF50182 8 70 3.47E-24 T 06-07-2017 IPR010920 LSM domain CAL12_RS09250 7b8208d3fc5a94a29898f033b8c096be 78 Gene3D G3DSA:2.30.30.100 2 71 6.7E-37 T 06-07-2017 CAL12_RS09250 7b8208d3fc5a94a29898f033b8c096be 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 3.9E-29 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CAL12_RS09250 7b8208d3fc5a94a29898f033b8c096be 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 28.324 T 06-07-2017 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 Pfam PF01614 Bacterial transcriptional regulator 168 232 6.2E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 Pfam PF09339 IclR helix-turn-helix domain 19 62 2.4E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 SUPERFAMILY SSF46785 17 91 1.16E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 SUPERFAMILY SSF55781 84 237 2.22E-29 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 Gene3D G3DSA:3.30.450.40 84 238 1.7E-32 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 Gene3D G3DSA:1.10.10.10 17 80 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02105 92573240d294228ed241eefe41448ac1 250 SMART SM00346 17 107 2.5E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 SUPERFAMILY SSF51905 1 152 1.62E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 SUPERFAMILY SSF51905 254 368 1.62E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 438 766 1.4E-57 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 Gene3D G3DSA:3.50.50.60 1 42 1.7E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 Gene3D G3DSA:3.50.50.60 263 403 1.7E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 Gene3D G3DSA:3.50.50.60 96 168 1.7E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 SUPERFAMILY SSF51395 435 789 1.13E-112 T 06-07-2017 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 Gene3D G3DSA:3.20.20.70 435 767 3.6E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 4.1E-8 T 06-07-2017 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 4.1E-8 T 06-07-2017 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 4.1E-8 T 06-07-2017 CAL12_RS25010 120df76fb74ec8c1806f69bdadd3bfd7 811 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-8 T 06-07-2017 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 Gene3D G3DSA:3.30.930.10 159 506 8.3E-112 T 06-07-2017 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 24 510 43.542 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 SUPERFAMILY SSF50249 17 157 8.76E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 SUPERFAMILY SSF55681 164 508 8.89E-115 T 06-07-2017 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 Pfam PF01336 OB-fold nucleic acid binding domain 71 147 1.0E-15 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 Pfam PF00152 tRNA synthetases class II (D, K and N) 164 507 3.0E-81 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 19 509 8.6E-194 T 06-07-2017 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 Gene3D G3DSA:2.40.50.140 19 156 5.9E-47 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 1.1E-37 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 1.1E-37 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 1.1E-37 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 1.1E-37 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS17135 6cdc24c5cc01eb35f4c57b54dc2117e7 511 PRINTS PR00982 Lysyl-tRNA synthetase signature 392 408 1.1E-37 T 06-07-2017 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 26 156 1.1E-53 T 06-07-2017 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 24 46 1.5E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 SUPERFAMILY SSF54523 54 156 1.2E-34 T 06-07-2017 CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 Pfam PF08334 Type II secretion system (T2SS), protein G 50 156 1.8E-40 T 06-07-2017 IPR013545 Type II secretion system protein G CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 25 47 1.4E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 PRINTS PR00813 Bacterial general secretion pathway protein G signature 27 52 4.5E-17 T 06-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 PRINTS PR00813 Bacterial general secretion pathway protein G signature 63 81 4.5E-17 T 06-07-2017 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 26 46 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27310 b220927f9dccaf17da3adcc55b91e332 158 Gene3D G3DSA:3.30.700.10 28 94 8.0E-9 T 06-07-2017 CAL12_RS13495 20df578b7c671e638cfcaf4cfec1c3db 392 Pfam PF10005 zinc-ribbon domain 25 121 4.3E-25 T 06-07-2017 IPR011201 Zinc-ribbon domain, bacteria CAL12_RS13495 20df578b7c671e638cfcaf4cfec1c3db 392 Pfam PF15887 Putative zinc-binding metallo-peptidase 126 375 1.1E-99 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CAL12_RS13495 20df578b7c671e638cfcaf4cfec1c3db 392 PIRSF PIRSF012641 22 391 3.2E-123 T 06-07-2017 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 06-07-2017 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 418 7.1E-186 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 418 1.8E-124 T 06-07-2017 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 418 50.081 T 06-07-2017 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 Gene3D G3DSA:1.10.645.10 6 257 3.0E-45 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 Gene3D G3DSA:1.10.645.10 259 404 7.1E-18 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 SUPERFAMILY SSF56762 194 418 1.44E-138 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19695 77081cd13192e4a072e2de0cf5e27ec8 418 SUPERFAMILY SSF56762 16 167 1.44E-138 T 06-07-2017 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 Gene3D G3DSA:1.10.10.10 234 292 3.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 89 102 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 SUPERFAMILY SSF88946 27 134 3.53E-40 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 Pfam PF04542 Sigma-70 region 2 65 134 1.5E-19 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 PIRSF PIRSF000770 30 295 9.8E-34 T 06-07-2017 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 Pfam PF04545 Sigma-70, region 4 238 289 2.1E-16 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 290 4.5E-35 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 SUPERFAMILY SSF88659 199 293 9.53E-19 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 27 292 2.8E-122 T 06-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 9 294 51.602 T 06-07-2017 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 Gene3D G3DSA:1.10.601.10 28 134 4.4E-37 T 06-07-2017 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 262 288 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 PRINTS PR00046 Major sigma-70 factor signature 89 102 5.6E-19 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 PRINTS PR00046 Major sigma-70 factor signature 242 254 5.6E-19 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 PRINTS PR00046 Major sigma-70 factor signature 262 277 5.6E-19 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00945 54eb8df42decf118adfaaa2b56b09e68 295 PRINTS PR00046 Major sigma-70 factor signature 277 288 5.6E-19 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS03645 c4147514f0840be7dce23dc20e18b89a 294 Gene3D G3DSA:3.40.50.150 4 139 4.2E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS03645 c4147514f0840be7dce23dc20e18b89a 294 Pfam PF13649 Methyltransferase domain 48 138 5.8E-9 T 06-07-2017 CAL12_RS03645 c4147514f0840be7dce23dc20e18b89a 294 SUPERFAMILY SSF53335 17 273 1.76E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.4E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 Gene3D G3DSA:3.40.190.10 165 260 6.3E-21 T 06-07-2017 CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 Gene3D G3DSA:1.10.10.10 3 84 9.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 SUPERFAMILY SSF46785 4 111 1.75E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 SUPERFAMILY SSF53850 90 296 1.01E-40 T 06-07-2017 CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 Pfam PF03466 LysR substrate binding domain 89 293 4.9E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16900 ab9d1e427eeea266cba1a5752306054e 303 Gene3D G3DSA:3.40.190.10 89 164 6.9E-4 T 06-07-2017 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.6E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.6E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.6E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 SUPERFAMILY SSF46785 1 86 1.82E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 Gene3D G3DSA:3.40.190.10 178 267 5.3E-28 T 06-07-2017 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 Pfam PF03466 LysR substrate binding domain 87 294 1.5E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.6E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 SUPERFAMILY SSF53850 88 298 9.19E-36 T 06-07-2017 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 Gene3D G3DSA:3.40.190.10 88 177 1.9E-23 T 06-07-2017 CAL12_RS04610 5edea5d3aa51b437f11f0bdd51cf52c8 301 Gene3D G3DSA:1.10.10.10 1 85 9.9E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 SUPERFAMILY SSF53623 132 275 1.28E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 SUPERFAMILY SSF53623 312 365 1.28E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Gene3D G3DSA:3.40.50.720 14 112 2.1E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Pfam PF02875 Mur ligase family, glutamate ligase domain 370 438 2.0E-5 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 SUPERFAMILY SSF51984 14 113 2.55E-11 T 06-07-2017 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Pfam PF08245 Mur ligase middle domain 139 273 8.7E-28 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 503 6.2E-109 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 SUPERFAMILY SSF53244 367 506 1.5E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Gene3D G3DSA:3.40.1190.10 114 273 6.2E-65 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Gene3D G3DSA:3.40.1190.10 305 366 6.2E-65 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 506 32.023 T 06-07-2017 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22420 361752e696bfe17a3df4c659ca58079d 514 Gene3D G3DSA:3.90.190.20 369 501 3.7E-47 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS11500 2df9c40855cdad1214c856f2a6f621b0 139 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 8 38 6.1E-5 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11500 2df9c40855cdad1214c856f2a6f621b0 139 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 45 139 3.1E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 432 1.0E-66 T 06-07-2017 IPR021886 MgsA AAA+ ATPase C-terminal CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 SUPERFAMILY SSF48019 253 434 5.1E-72 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 SUPERFAMILY SSF52540 13 237 1.9E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Pfam PF16193 AAA C-terminal domain 191 268 1.4E-21 T 06-07-2017 IPR032423 AAA ATPase, C-terminal domain CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Gene3D G3DSA:1.20.272.10 250 348 4.3E-43 T 06-07-2017 CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Gene3D G3DSA:1.10.8.60 156 225 4.3E-7 T 06-07-2017 CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Gene3D G3DSA:1.10.3710.10 349 443 5.4E-33 T 06-07-2017 CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 SMART SM00382 51 167 4.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 161 1.2E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS21440 af40a7bf532d445f1cca6f5914701b5c 446 Gene3D G3DSA:3.40.50.300 13 155 3.1E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12705 13fc4d07562a5f301b4cc9b5cc46fa46 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 4.1E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12705 13fc4d07562a5f301b4cc9b5cc46fa46 323 PIRSF PIRSF017082 1 322 1.4E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12705 13fc4d07562a5f301b4cc9b5cc46fa46 323 SUPERFAMILY SSF53850 109 282 1.19E-9 T 06-07-2017 CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Gene3D G3DSA:3.40.50.300 23 52 5.0E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Gene3D G3DSA:3.40.50.300 93 208 5.8E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Gene3D G3DSA:3.40.50.300 9 22 5.8E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 SUPERFAMILY SSF52540 9 194 2.48E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 SMART SM00072 10 192 3.1E-57 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Hamap MF_00328 Guanylate kinase [gmk]. 9 192 35.748 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Pfam PF00625 Guanylate kinase 14 190 2.0E-43 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 11 189 1.6E-68 T 06-07-2017 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 ProSitePatterns PS00856 Guanylate kinase-like signature. 45 62 - T 06-07-2017 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CAL12_RS15430 650e99b8f5806a1d17915d952177d51a 215 Gene3D G3DSA:3.30.63.10 53 92 4.5E-25 T 06-07-2017 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 191 297 1.9E-22 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.90.1170.50 10 135 2.5E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 301 376 7.3E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 136 190 7.3E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 471 651 8.0E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.530.20 868 1017 1.2E-44 T 06-07-2017 IPR023393 START-like domain CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 378 470 4.7E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Gene3D G3DSA:3.30.365.10 666 810 4.7E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 869 1006 9.4E-27 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 SUPERFAMILY SSF55961 868 1008 1.96E-34 T 06-07-2017 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 163 751 9.2E-146 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 146 3.9E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 SUPERFAMILY SSF54665 17 168 1.57E-43 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 SUPERFAMILY SSF56003 139 810 1.57E-163 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15840 63c0c143fd312adb899c1585be2377c3 1032 SMART SM01008 36 147 6.6E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Gene3D G3DSA:3.40.440.10 191 280 8.9E-41 T 06-07-2017 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Gene3D G3DSA:3.40.440.10 337 412 8.9E-41 T 06-07-2017 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Gene3D G3DSA:3.90.170.10 452 500 4.6E-8 T 06-07-2017 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 SUPERFAMILY SSF52540 2 183 9.2E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Pfam PF13238 AAA domain 7 130 2.1E-7 T 06-07-2017 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 101 562 37.548 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Pfam PF00709 Adenylosuccinate synthetase 349 499 2.8E-24 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Pfam PF00709 Adenylosuccinate synthetase 193 324 2.8E-24 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 SMART SM00788 191 545 3.1E-55 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS16970 045147b01661ab54fa9e213771950454 562 Gene3D G3DSA:3.40.50.300 6 173 1.8E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16970 045147b01661ab54fa9e213771950454 562 SUPERFAMILY SSF52540 191 539 4.65E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 Pfam PF02682 Allophanate hydrolase subunit 1 12 218 5.8E-65 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 SUPERFAMILY SSF160467 13 110 2.62E-15 T 06-07-2017 CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 SUPERFAMILY SSF50891 105 235 6.45E-42 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 Gene3D G3DSA:3.30.1360.40 13 88 2.0E-16 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 Gene3D G3DSA:2.40.100.10 105 240 6.9E-46 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 17 228 7.6E-51 T 06-07-2017 IPR010016 KipI family CAL12_RS08695 9ca18a71db9db376b6b7b8b6f8bec018 243 SMART SM00796 12 219 5.6E-85 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 SMART SM00382 28 211 1.1E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 SUPERFAMILY SSF52540 4 241 5.19E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 Gene3D G3DSA:3.40.50.300 4 232 6.8E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 SUPERFAMILY SSF50331 253 342 9.35E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 Pfam PF00005 ABC transporter 20 161 7.8E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07085 3aefc4046a92d4096b3dc083a518e09e 351 Pfam PF08402 TOBE domain 272 342 2.5E-11 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 Gene3D G3DSA:3.20.20.140 62 355 1.3E-69 T 06-07-2017 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 Gene3D G3DSA:2.30.40.10 356 380 3.1E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 Pfam PF01979 Amidohydrolase family 55 409 2.0E-22 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 SUPERFAMILY SSF51556 59 365 1.62E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS12500 da19560324fbdef4559423bd484da951 426 SUPERFAMILY SSF51338 371 410 5.19E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 SUPERFAMILY SSF51338 1 59 5.19E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 Gene3D G3DSA:2.30.40.10 381 413 9.3E-24 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12500 da19560324fbdef4559423bd484da951 426 Gene3D G3DSA:2.30.40.10 2 60 9.3E-24 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS16385 8c326ceb8d53280bcfe680eb58cee2ba 172 Pfam PF01625 Peptide methionine sulfoxide reductase 6 152 1.9E-57 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16385 8c326ceb8d53280bcfe680eb58cee2ba 172 Gene3D G3DSA:3.30.1060.10 2 153 7.7E-67 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16385 8c326ceb8d53280bcfe680eb58cee2ba 172 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 5 152 8.3E-51 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16385 8c326ceb8d53280bcfe680eb58cee2ba 172 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 34.394 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16385 8c326ceb8d53280bcfe680eb58cee2ba 172 SUPERFAMILY SSF55068 2 161 1.57E-65 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 Pfam PF02272 DHHA1 domain 799 867 2.8E-14 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 651 693 1.0E-15 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 SUPERFAMILY SSF50447 451 550 2.16E-19 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 SUPERFAMILY SSF55186 550 708 8.24E-50 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 SUPERFAMILY SSF101353 252 442 1.83E-60 T 06-07-2017 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 SUPERFAMILY SSF55681 2 251 1.14E-107 T 06-07-2017 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 1.3E-31 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 1.3E-31 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 1.3E-31 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 1.3E-31 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 1.3E-31 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 Pfam PF01411 tRNA synthetases class II (A) 5 552 6.6E-221 T 06-07-2017 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 SMART SM00863 651 693 2.3E-19 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 Gene3D G3DSA:3.30.930.10 1 248 9.0E-124 T 06-07-2017 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 852 0.0 T 06-07-2017 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CAL12_RS09175 cabcc31aece91ff8e76bc7ce1212b01a 873 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 873 201.172 T 06-07-2017 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CAL12_RS16295 5e6d28c5ece334c19b990a4f91cfda2d 264 SUPERFAMILY SSF52540 8 239 5.71E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16295 5e6d28c5ece334c19b990a4f91cfda2d 264 Gene3D G3DSA:3.40.50.300 5 215 8.3E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16295 5e6d28c5ece334c19b990a4f91cfda2d 264 SMART SM00382 33 217 2.1E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS16295 5e6d28c5ece334c19b990a4f91cfda2d 264 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS16295 5e6d28c5ece334c19b990a4f91cfda2d 264 Pfam PF00005 ABC transporter 25 167 5.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 SMART SM00346 29 117 8.3E-4 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 SUPERFAMILY SSF46785 31 90 2.82E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 Gene3D G3DSA:1.10.10.10 25 90 2.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 Pfam PF01614 Bacterial transcriptional regulator 149 261 5.4E-10 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 Pfam PF09339 IclR helix-turn-helix domain 32 83 4.0E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 Gene3D G3DSA:3.30.450.40 104 262 9.8E-29 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13955 084a8591054e91486ad8e6405abfa421 267 SUPERFAMILY SSF55781 104 264 2.42E-30 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 Gene3D G3DSA:1.10.10.60 230 277 2.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 SMART SM00342 192 275 2.9E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 Pfam PF12833 Helix-turn-helix domain 198 276 2.6E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 SUPERFAMILY SSF46689 228 276 6.57E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 Pfam PF02311 AraC-like ligand binding domain 25 135 4.5E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 177 221 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 Gene3D G3DSA:1.10.10.60 174 229 2.8E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 2.0E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 2.0E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 SUPERFAMILY SSF51215 26 152 8.24E-7 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS03300 1df451c7499a5b025e85946f4b6f250a 287 SUPERFAMILY SSF46689 175 223 8.56E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 Pfam PF07690 Major Facilitator Superfamily 25 390 9.2E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 27 427 2.1E-128 T 06-07-2017 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 PIRSF PIRSF002808 11 434 4.2E-37 T 06-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 SUPERFAMILY SSF103473 12 429 4.58E-81 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 Gene3D G3DSA:1.20.1250.20 15 206 2.1E-53 T 06-07-2017 CAL12_RS02215 00e9d11ee4db58ed028fe1370d1412a0 435 Gene3D G3DSA:1.20.1250.20 241 429 4.1E-23 T 06-07-2017 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Pfam PF09107 Elongation factor SelB, winged helix 599 637 3.6E-17 T 06-07-2017 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF52540 2 194 7.52E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Pfam PF09106 Elongation factor SelB, winged helix 449 504 1.1E-15 T 06-07-2017 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF46785 439 510 2.29E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Gene3D G3DSA:1.10.10.10 513 573 3.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Pfam PF00009 Elongation factor Tu GTP binding domain 2 130 1.8E-24 T 06-07-2017 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Gene3D G3DSA:1.10.10.10 597 638 1.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF50447 175 265 4.64E-18 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF50465 273 369 1.2E-18 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 PRINTS PR00315 GTP-binding elongation factor signature 70 81 9.6E-5 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 PRINTS PR00315 GTP-binding elongation factor signature 2 15 9.6E-5 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 PRINTS PR00315 GTP-binding elongation factor signature 54 64 9.6E-5 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Gene3D G3DSA:1.10.10.10 439 505 6.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 638 8.5E-122 T 06-07-2017 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Gene3D G3DSA:2.40.30.10 177 303 3.1E-26 T 06-07-2017 CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF46785 512 574 7.71E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 SUPERFAMILY SSF46785 578 639 1.09E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19455 9cf12dec156063a79c8fcdc469c90feb 655 Gene3D G3DSA:3.40.50.300 3 149 8.1E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00200 7ba902c1d68cd3bc0bf1fa99d435accf 356 SUPERFAMILY SSF53850 145 319 3.26E-14 T 06-07-2017 CAL12_RS00200 7ba902c1d68cd3bc0bf1fa99d435accf 356 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 80 352 1.0E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00200 7ba902c1d68cd3bc0bf1fa99d435accf 356 PIRSF PIRSF017082 22 355 2.2E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 261 6.9E-48 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 Gene3D G3DSA:3.40.190.10 29 109 2.5E-28 T 06-07-2017 CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 Gene3D G3DSA:3.40.190.10 221 263 2.5E-28 T 06-07-2017 CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 SMART SM00062 32 263 6.6E-41 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 Gene3D G3DSA:3.40.190.10 110 220 6.8E-20 T 06-07-2017 CAL12_RS25495 dab5a8c5e42480284fc75e94d5d27e1f 276 SUPERFAMILY SSF53850 1 262 6.86E-53 T 06-07-2017 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 292 6.8E-131 T 06-07-2017 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 SUPERFAMILY SSF48179 162 292 5.89E-41 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 PIRSF PIRSF000103 1 293 1.0E-79 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 291 4.9E-35 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 Gene3D G3DSA:3.40.50.720 3 162 2.7E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 8.3E-52 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 Gene3D G3DSA:1.10.1040.10 163 292 6.5E-45 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 SUPERFAMILY SSF51735 3 162 8.06E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12255 14cf840beb05d4e5d44b3acf39fb443e 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 5.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 5.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 5.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 Gene3D G3DSA:3.40.190.10 204 277 3.1E-6 T 06-07-2017 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 75 1.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 Pfam PF03466 LysR substrate binding domain 102 305 1.9E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 SUPERFAMILY SSF53850 102 305 2.84E-27 T 06-07-2017 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 Gene3D G3DSA:3.40.190.10 104 203 9.5E-16 T 06-07-2017 CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 Gene3D G3DSA:1.10.10.10 15 94 4.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27735 e3b464466ea3f05abf43f70fc009d8b8 317 SUPERFAMILY SSF46785 14 123 1.16E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 Gene3D G3DSA:3.30.420.40 253 514 4.0E-101 T 06-07-2017 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 513 1.0E-213 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 379 399 - T 06-07-2017 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 467 1.6E-59 T 06-07-2017 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 251 1.4E-78 T 06-07-2017 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 SUPERFAMILY SSF53067 254 513 9.5E-79 T 06-07-2017 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 Gene3D G3DSA:3.30.420.40 1 252 7.5E-101 T 06-07-2017 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 PIRSF PIRSF000538 3 516 4.0E-172 T 06-07-2017 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 SUPERFAMILY SSF53067 5 254 2.19E-93 T 06-07-2017 CAL12_RS25155 2b8018474d985ddee6251df5cb6d6fe6 518 Hamap MF_00186 Glycerol kinase [glpK]. 3 514 56.249 T 06-07-2017 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 Pfam PF00672 HAMP domain 194 260 1.2E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 SMART SM00283 266 513 7.1E-89 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 320 512 4.6E-59 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 182 6.0E-12 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 SMART SM00304 213 265 2.6E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 Gene3D G3DSA:1.10.287.950 281 485 1.7E-59 T 06-07-2017 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 SUPERFAMILY SSF58104 233 518 2.49E-75 T 06-07-2017 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.5E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.5E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.5E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 7 32 1.5E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS20620 8ae8766cdd7a5888c23b1df89f7b0762 548 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.5E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS17535 2217eb4f59b378015dbc2d1bd4304a03 636 Pfam PF02705 K+ potassium transporter 26 556 6.7E-202 T 06-07-2017 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 CAL12_RS17535 2217eb4f59b378015dbc2d1bd4304a03 636 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 17 636 33.036 T 06-07-2017 IPR023051 Potassium uptake protein, low affinity, Kup CAL12_RS02110 f22c65ff9ea41cd303472df13c81f03f 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 1.3E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02110 f22c65ff9ea41cd303472df13c81f03f 324 Gene3D G3DSA:3.40.190.10 129 238 2.0E-4 T 06-07-2017 CAL12_RS02110 f22c65ff9ea41cd303472df13c81f03f 324 PIRSF PIRSF017082 1 323 7.9E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02110 f22c65ff9ea41cd303472df13c81f03f 324 SUPERFAMILY SSF53850 89 231 8.54E-10 T 06-07-2017 CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Gene3D G3DSA:3.40.50.300 421 450 1.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Gene3D G3DSA:3.40.50.300 155 387 1.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Pfam PF13604 AAA domain 204 387 1.2E-27 T 06-07-2017 CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 31 716 2.8E-166 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Gene3D G3DSA:3.40.50.300 638 697 8.1E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 SUPERFAMILY SSF52540 32 431 1.79E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Pfam PF13538 UvrD-like helicase C-terminal domain 646 692 9.2E-15 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 SUPERFAMILY SSF52540 351 390 1.44E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 SUPERFAMILY SSF52540 418 449 1.44E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 SUPERFAMILY SSF52540 541 698 1.44E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01565 4db68506952aa43a0ae515f0bfb264d8 717 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 39 717 46.915 T 06-07-2017 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 Gene3D G3DSA:3.40.190.10 179 258 4.9E-8 T 06-07-2017 CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 SUPERFAMILY SSF53850 90 296 2.33E-49 T 06-07-2017 CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 SUPERFAMILY SSF46785 2 88 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 Gene3D G3DSA:1.10.10.10 1 87 3.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 Gene3D G3DSA:3.40.190.10 93 178 1.9E-23 T 06-07-2017 CAL12_RS10800 c366033e76a2732542f942c22f7179b6 304 Pfam PF03466 LysR substrate binding domain 89 292 8.0E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 Pfam PF00672 HAMP domain 207 274 3.5E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 SUPERFAMILY SSF158472 226 274 1.22E-5 T 06-07-2017 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 SMART SM00304 226 277 3.9E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 Gene3D G3DSA:1.10.287.130 268 330 8.9E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 SUPERFAMILY SSF47384 261 332 1.61E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 486 4.9E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 Gene3D G3DSA:3.30.565.10 362 486 4.6E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 SMART SM00387 378 487 2.0E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 4.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 4.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 4.2E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05540 bdb315aa592f6a27b625b6f28901e136 487 SUPERFAMILY SSF55874 339 486 1.31E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Hamap MF_00974 DNA primase [dnaG]. 1 668 27.361 T 06-07-2017 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SMART SM00400 33 87 4.2E-34 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Gene3D G3DSA:1.10.860.10 530 664 3.8E-8 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 TIGRFAM TIGR01391 dnaG: DNA primase 2 412 1.7E-134 T 06-07-2017 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Pfam PF10410 DnaB-helicase binding domain of primase 366 421 1.1E-9 T 06-07-2017 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Gene3D G3DSA:3.90.580.10 2 98 2.4E-39 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SMART SM00766 537 661 8.8E-15 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SMART SM00493 256 327 1.2E-19 T 06-07-2017 IPR006171 Toprim domain CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SUPERFAMILY SSF57783 2 98 3.06E-36 T 06-07-2017 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Pfam PF13662 Toprim domain 257 322 1.2E-14 T 06-07-2017 IPR006171 Toprim domain CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Gene3D G3DSA:1.20.50.20 365 422 2.3E-18 T 06-07-2017 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Pfam PF08278 DNA primase DnaG DnaB-binding 539 660 4.6E-13 T 06-07-2017 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SUPERFAMILY SSF117023 535 663 5.23E-13 T 06-07-2017 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 SUPERFAMILY SSF56731 119 419 1.44E-99 T 06-07-2017 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Gene3D G3DSA:3.90.980.10 119 237 6.2E-39 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Gene3D G3DSA:3.40.1360.10 238 362 3.0E-44 T 06-07-2017 CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Pfam PF08275 DNA primase catalytic core, N-terminal domain 128 248 7.8E-36 T 06-07-2017 IPR013264 DNA primase, catalytic core, N-terminal CAL12_RS09290 ffb050d982a8e6589a69b3b905cbad05 676 Pfam PF01807 CHC2 zinc finger 3 97 1.6E-36 T 06-07-2017 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 Gene3D G3DSA:3.40.50.300 1 236 1.6E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 PIRSF PIRSF039085 1 241 3.7E-102 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 Pfam PF00005 ABC transporter 17 165 9.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 SMART SM00382 26 213 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07500 02d4e18bc9ed44d6c66c180a569c64ee 241 SUPERFAMILY SSF52540 1 235 2.54E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Gene3D G3DSA:3.30.70.260 684 753 1.0E-4 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Gene3D G3DSA:3.30.70.260 803 853 1.5E-10 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 880 308.236 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SUPERFAMILY SSF55021 684 741 2.71E-8 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Pfam PF08335 GlnD PII-uridylyltransferase 174 312 5.6E-31 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SUPERFAMILY SSF81301 7 166 2.13E-23 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SMART SM00471 445 592 1.2E-6 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 PIRSF PIRSF006288 6 879 0.0 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SUPERFAMILY SSF109604 417 540 2.56E-15 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 36 869 9.9E-234 T 06-07-2017 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Pfam PF01966 HD domain 450 552 2.3E-9 T 06-07-2017 IPR006674 HD domain CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SUPERFAMILY SSF81593 181 286 3.37E-8 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 SUPERFAMILY SSF55021 800 856 1.57E-9 T 06-07-2017 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Pfam PF01909 Nucleotidyltransferase domain 68 131 1.9E-6 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Gene3D G3DSA:1.10.3210.10 423 602 5.5E-23 T 06-07-2017 IPR006674 HD domain CAL12_RS12105 6fa77aafc1004f6d6510af833ca96ed7 880 Gene3D G3DSA:3.30.460.10 73 161 5.0E-6 T 06-07-2017 CAL12_RS11225 b490a8657648c153944a4e202bd397c3 463 Gene3D G3DSA:3.20.20.140 58 401 1.9E-64 T 06-07-2017 CAL12_RS11225 b490a8657648c153944a4e202bd397c3 463 SUPERFAMILY SSF51556 54 381 3.58E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS11225 b490a8657648c153944a4e202bd397c3 463 Pfam PF01979 Amidohydrolase family 52 435 1.4E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS11225 b490a8657648c153944a4e202bd397c3 463 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 5 459 1.2E-178 T 06-07-2017 IPR010252 Formiminoglutamate deiminase CAL12_RS11225 b490a8657648c153944a4e202bd397c3 463 SUPERFAMILY SSF51338 353 451 9.21E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 Pfam PF00464 Serine hydroxymethyltransferase 8 382 5.7E-171 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 SUPERFAMILY SSF53383 6 414 4.21E-177 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 51.962 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 06-07-2017 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 Gene3D G3DSA:3.90.1150.10 282 414 3.7E-55 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 Gene3D G3DSA:3.40.640.10 37 281 9.8E-98 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS24705 6780b490f2eb93573a569b191da5dfc4 414 PIRSF PIRSF000412 1 414 5.2E-165 T 06-07-2017 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 SUPERFAMILY SSF52402 153 276 1.0E-18 T 06-07-2017 CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 PRINTS PR01438 Universal stress protein signature 152 170 1.7E-5 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 PRINTS PR01438 Universal stress protein signature 256 278 1.7E-5 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 PRINTS PR01438 Universal stress protein signature 238 250 1.7E-5 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 Gene3D G3DSA:3.40.50.620 1 143 3.0E-9 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 SUPERFAMILY SSF52402 1 143 2.51E-14 T 06-07-2017 CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 Pfam PF00582 Universal stress protein family 1 143 4.3E-5 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 Pfam PF00582 Universal stress protein family 154 275 3.0E-8 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS14260 bec2c1ebda6376d10100a0e99ca7eb22 278 Gene3D G3DSA:3.40.50.620 153 277 1.8E-15 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.4E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 Pfam PF03466 LysR substrate binding domain 93 298 2.6E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 Gene3D G3DSA:3.40.190.10 96 196 3.2E-20 T 06-07-2017 CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 SUPERFAMILY SSF53850 94 300 2.35E-32 T 06-07-2017 CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 SUPERFAMILY SSF46785 7 87 1.85E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05465 fac72bd2eeb1d81c7c1d2b0edfbbc482 306 Gene3D G3DSA:1.10.10.10 7 87 2.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Pfam PF00072 Response regulator receiver domain 568 676 1.2E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SUPERFAMILY SSF47384 307 379 7.85E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00388 316 382 1.3E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Gene3D G3DSA:1.10.287.130 310 378 2.5E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00091 178 245 8.7E-6 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00091 50 117 0.11 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 62 173 1.7E-22 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 177 301 2.5E-23 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Pfam PF00512 His Kinase A (phospho-acceptor) domain 318 380 2.3E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Gene3D G3DSA:3.30.450.20 63 163 2.2E-23 T 06-07-2017 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SUPERFAMILY SSF52172 566 677 9.68E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00448 566 676 3.5E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 424 542 8.0E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Gene3D G3DSA:3.30.450.20 164 292 5.2E-30 T 06-07-2017 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 7.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 541 7.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 487 7.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 501 7.1E-17 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SUPERFAMILY SSF55874 372 545 1.83E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00086 252 294 0.033 T 06-07-2017 IPR001610 PAC motif CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00086 124 166 0.091 T 06-07-2017 IPR001610 PAC motif CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SUPERFAMILY SSF55785 162 289 4.67E-30 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Gene3D G3DSA:3.30.565.10 382 543 2.6E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Pfam PF13426 PAS domain 191 293 1.2E-14 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Pfam PF13426 PAS domain 63 165 2.2E-14 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SUPERFAMILY SSF55785 63 173 5.06E-25 T 06-07-2017 IPR000014 PAS domain CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 Gene3D G3DSA:3.40.50.2300 565 676 2.0E-25 T 06-07-2017 CAL12_RS01570 b9feada5c874938eae7765c16471bb83 713 SMART SM00387 423 544 3.9E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS06730 6421af4c1373491235e19eca5394fde5 461 Pfam PF03313 Serine dehydratase alpha chain 190 455 1.8E-106 T 06-07-2017 IPR005130 Serine dehydratase-like, alpha subunit CAL12_RS06730 6421af4c1373491235e19eca5394fde5 461 Pfam PF03315 Serine dehydratase beta chain 4 155 2.7E-58 T 06-07-2017 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CAL12_RS06730 6421af4c1373491235e19eca5394fde5 461 Gene3D G3DSA:3.30.1330.90 11 156 2.1E-54 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAL12_RS06730 6421af4c1373491235e19eca5394fde5 461 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 458 1.6E-210 T 06-07-2017 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CAL12_RS06730 6421af4c1373491235e19eca5394fde5 461 SUPERFAMILY SSF143548 17 156 1.52E-47 T 06-07-2017 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CAL12_RS16545 31c0c6dd477f3147ad916cfcb6684034 290 Pfam PF05368 NmrA-like family 3 221 3.5E-25 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAL12_RS16545 31c0c6dd477f3147ad916cfcb6684034 290 SUPERFAMILY SSF51735 3 259 2.42E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16545 31c0c6dd477f3147ad916cfcb6684034 290 Gene3D G3DSA:3.40.50.720 1 220 1.2E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23430 07cbf65dcf82335f2945fd219fbe0353 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 322 5.2E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23430 07cbf65dcf82335f2945fd219fbe0353 325 SUPERFAMILY SSF53850 111 290 3.75E-13 T 06-07-2017 CAL12_RS23430 07cbf65dcf82335f2945fd219fbe0353 325 PIRSF PIRSF017082 2 325 4.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21690 500ec089a60ea537ff4f081a7cdbdae8 117 Pfam PF00034 Cytochrome c 46 116 4.8E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21690 500ec089a60ea537ff4f081a7cdbdae8 117 Gene3D G3DSA:1.10.760.10 35 116 6.6E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21690 500ec089a60ea537ff4f081a7cdbdae8 117 SUPERFAMILY SSF46626 13 117 1.89E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 Pfam PF01476 LysM domain 66 109 4.6E-13 T 06-07-2017 IPR018392 LysM domain CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 Gene3D G3DSA:2.70.70.10 177 304 5.3E-38 T 06-07-2017 CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 SUPERFAMILY SSF51261 66 303 3.3E-45 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 SMART SM00257 65 109 1.2E-16 T 06-07-2017 IPR018392 LysM domain CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 Gene3D G3DSA:3.10.350.10 64 109 4.0E-18 T 06-07-2017 IPR018392 LysM domain CAL12_RS15975 f5b8ee84477118c2aa4aa79fd4f8f7a7 306 Pfam PF01551 Peptidase family M23 205 299 6.8E-30 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS14595 c46664eba63d9d81653c5c450a8604ff 339 SUPERFAMILY SSF53187 38 316 6.95E-33 T 06-07-2017 CAL12_RS14595 c46664eba63d9d81653c5c450a8604ff 339 PIRSF PIRSF039012 3 338 2.6E-59 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS14595 c46664eba63d9d81653c5c450a8604ff 339 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 46 326 7.9E-28 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS14595 c46664eba63d9d81653c5c450a8604ff 339 Gene3D G3DSA:3.40.630.10 26 152 2.5E-13 T 06-07-2017 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 Gene3D G3DSA:3.40.309.10 261 442 2.5E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 SUPERFAMILY SSF53720 2 482 2.75E-154 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 Pfam PF00171 Aldehyde dehydrogenase family 19 477 3.3E-144 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 481 1.1E-215 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 Gene3D G3DSA:3.40.605.10 3 260 1.9E-92 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS02665 8d8bd58cab0b2b652baec2c1e2f324f8 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 SUPERFAMILY SSF53187 10 231 6.29E-86 T 06-07-2017 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 SUPERFAMILY SSF53187 342 415 6.29E-86 T 06-07-2017 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 Gene3D G3DSA:3.30.70.360 235 327 1.3E-25 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 Pfam PF07687 Peptidase dimerisation domain 219 319 1.8E-5 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 SUPERFAMILY SSF55031 221 326 9.72E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 Pfam PF01546 Peptidase family M20/M25/M40 87 412 2.6E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 Gene3D G3DSA:3.40.630.10 357 416 8.8E-105 T 06-07-2017 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 Gene3D G3DSA:3.40.630.10 12 234 8.8E-105 T 06-07-2017 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 15 413 3.2E-112 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS02065 a06a4f9b3d53ca975401a295863b22ec 420 PIRSF PIRSF001235 10 419 4.3E-123 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS08840 582b527b0b4b25d0b74a710fc33e3d95 318 Pfam PF00248 Aldo/keto reductase family 15 314 5.2E-68 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS08840 582b527b0b4b25d0b74a710fc33e3d95 318 Gene3D G3DSA:3.20.20.100 1 314 2.1E-93 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS08840 582b527b0b4b25d0b74a710fc33e3d95 318 SUPERFAMILY SSF51430 1 314 1.7E-93 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 Gene3D G3DSA:3.40.190.10 181 269 5.4E-21 T 06-07-2017 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 2.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 Gene3D G3DSA:3.40.190.10 97 180 5.1E-21 T 06-07-2017 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 SUPERFAMILY SSF53850 95 302 2.71E-39 T 06-07-2017 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 Gene3D G3DSA:1.10.10.10 13 89 6.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 Pfam PF03466 LysR substrate binding domain 94 301 1.6E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11435 604526d3e0c752f34cade2c3513091ed 303 SUPERFAMILY SSF46785 12 89 2.79E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 Gene3D G3DSA:3.10.20.30 1 102 6.4E-30 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 112 1.5E-53 T 06-07-2017 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 43 53 - T 06-07-2017 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 92 6.9E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 PRINTS PR00355 Adrenodoxin signature 61 75 2.8E-9 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 PRINTS PR00355 Adrenodoxin signature 43 53 2.8E-9 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 PRINTS PR00355 Adrenodoxin signature 84 92 2.8E-9 T 06-07-2017 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CAL12_RS17150 78204c24726afe5267c5bc7d1223d13e 113 SUPERFAMILY SSF54292 7 109 9.26E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 26 314 1.5E-76 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 Gene3D G3DSA:3.10.290.10 29 80 4.3E-11 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 Pfam PF00849 RNA pseudouridylate synthase 103 258 9.7E-29 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 145 159 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 Pfam PF01479 S4 domain 29 74 6.3E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 SMART SM00363 28 86 5.8E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 SUPERFAMILY SSF55120 88 316 2.67E-65 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS19180 8b81357bcfd7346b502e0b6e9e97a7e9 322 SUPERFAMILY SSF55174 29 79 7.06E-10 T 06-07-2017 CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 Gene3D G3DSA:3.40.50.300 4 232 6.9E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 SMART SM00382 29 216 9.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 Pfam PF00005 ABC transporter 20 168 2.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 PIRSF PIRSF039085 1 242 3.4E-100 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS10770 a87141dabd357bbb8beee994f04c02a5 242 SUPERFAMILY SSF52540 4 223 5.33E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 SUPERFAMILY SSF48008 102 239 9.15E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 Pfam PF07729 FCD domain 103 234 3.1E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 Gene3D G3DSA:1.10.10.10 8 75 5.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 SMART SM00345 14 73 6.7E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 Gene3D G3DSA:1.20.120.530 103 239 2.5E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 SUPERFAMILY SSF46785 1 77 7.72E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 SMART SM00895 103 235 1.6E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 2.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 1.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21805 ef391ddc57a07b5d84704aad06d4d0a0 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 1.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.387 T 06-07-2017 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 SMART SM00963 1 86 2.4E-33 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Gene3D G3DSA:3.40.50.300 99 310 3.1E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 SUPERFAMILY SSF52540 42 370 3.92E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 282 295 - T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 SUPERFAMILY SSF47446 311 445 9.68E-44 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Pfam PF00448 SRP54-type protein, GTPase domain 104 308 2.0E-67 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Pfam PF02978 Signal peptide binding domain 342 441 1.2E-31 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 SMART SM00962 104 309 9.5E-110 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Gene3D G3DSA:1.20.120.140 2 88 1.9E-34 T 06-07-2017 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 443 6.0E-169 T 06-07-2017 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 7.7E-20 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 SMART SM00382 103 283 3.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02255 797160bcf9850d97c7564cfc05d5cba1 469 Gene3D G3DSA:1.10.260.30 341 446 6.1E-37 T 06-07-2017 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 Pfam PF00582 Universal stress protein family 1 146 7.9E-31 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 PRINTS PR01438 Universal stress protein signature 2 20 5.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 PRINTS PR01438 Universal stress protein signature 106 118 5.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 PRINTS PR01438 Universal stress protein signature 124 146 5.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 SUPERFAMILY SSF52402 1 147 1.17E-34 T 06-07-2017 CAL12_RS14140 e6c54f90bc4377c638836a5fbf652360 158 Gene3D G3DSA:3.40.50.620 1 148 3.6E-37 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 SUPERFAMILY SSF51735 6 247 4.23E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 1.1E-60 T 06-07-2017 CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 Gene3D G3DSA:3.40.50.720 5 247 2.5E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16940 0f28552e9f129287ecbd345fcba679a4 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 19 35 5.7E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 78 5.7E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 41 57 5.7E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 293 5.7E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 Gene3D G3DSA:3.40.50.2300 17 217 4.1E-51 T 06-07-2017 CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 SUPERFAMILY SSF53822 18 365 5.23E-69 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS00375 7183923cbc8156aed1408d342e24ba7c 381 Pfam PF13458 Periplasmic binding protein 18 361 4.9E-58 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS18670 15588f1958eb7589a3708e53985556dd 172 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 20 171 2.1E-55 T 06-07-2017 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CAL12_RS18670 15588f1958eb7589a3708e53985556dd 172 Pfam PF01883 Domain of unknown function DUF59 11 76 3.3E-11 T 06-07-2017 IPR002744 Domain of unknown function DUF59 CAL12_RS18670 15588f1958eb7589a3708e53985556dd 172 SUPERFAMILY SSF117916 11 106 3.6E-21 T 06-07-2017 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 SUPERFAMILY SSF53697 248 610 2.23E-109 T 06-07-2017 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Gene3D G3DSA:3.40.50.10490 444 610 3.7E-63 T 06-07-2017 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 39.145 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Gene3D G3DSA:3.40.50.10490 247 443 1.6E-70 T 06-07-2017 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Pfam PF13522 Glutamine amidotransferase domain 64 195 1.3E-21 T 06-07-2017 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 8.7E-248 T 06-07-2017 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Gene3D G3DSA:3.60.20.10 2 241 5.7E-78 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Pfam PF01380 SIS domain 464 591 3.1E-25 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 Pfam PF01380 SIS domain 293 418 2.9E-27 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS01080 5efd88cdd262dff5e2514453a2b8c2e6 610 SUPERFAMILY SSF56235 2 237 3.77E-72 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 SUPERFAMILY SSF52540 6 256 1.85E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 Pfam PF00005 ABC transporter 34 184 7.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 321 1.8E-24 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 Gene3D G3DSA:3.40.50.300 6 257 2.2E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 2.6E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS13460 39345f9870a1a24b177f63da81f00536 327 SMART SM00382 42 234 3.8E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 PIRSF PIRSF017245 4 799 0.0 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 407 584 2.2E-83 T 06-07-2017 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 ProSitePatterns PS60003 Phosphoketolase signature 2. 165 183 - T 06-07-2017 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 Gene3D G3DSA:3.40.50.970 12 271 1.7E-16 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 Pfam PF09364 XFP N-terminal domain 18 392 2.5E-184 T 06-07-2017 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 SUPERFAMILY SSF52518 384 598 3.88E-24 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 Hamap MF_01403 Probable phosphoketolase. 13 799 39.885 T 06-07-2017 IPR023962 Probable phosphoketolase CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 SUPERFAMILY SSF52518 14 377 8.14E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 ProSitePatterns PS60002 Phosphoketolase signature 1. 152 158 - T 06-07-2017 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CAL12_RS21340 8fabdce9271749cc246ed8b1204229e5 799 Pfam PF09363 XFP C-terminal domain 596 797 1.2E-87 T 06-07-2017 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 SUPERFAMILY SSF46626 40 173 5.19E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 PRINTS PR00605 Class IC cytochrome C signature 348 359 6.5E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 PRINTS PR00605 Class IC cytochrome C signature 401 423 6.5E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 SUPERFAMILY SSF46626 200 311 8.88E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 Pfam PF00034 Cytochrome c 342 426 9.9E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 PIRSF PIRSF000018 17 457 1.9E-147 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 SUPERFAMILY SSF46626 342 443 4.15E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 Gene3D G3DSA:1.10.760.10 199 311 7.5E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 Gene3D G3DSA:1.10.760.10 48 149 5.4E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21190 2fe1d30d1bf25aa0f0e6e807da7c3e57 459 Gene3D G3DSA:1.10.760.10 342 446 4.6E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 Gene3D G3DSA:3.40.50.2300 9 130 1.7E-35 T 06-07-2017 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 SUPERFAMILY SSF46689 173 222 9.86E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 271 4.5E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 240 255 4.5E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 Pfam PF12833 Helix-turn-helix domain 194 272 3.3E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 SMART SM00448 11 125 2.2E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 Gene3D G3DSA:1.10.10.60 225 274 4.3E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 Pfam PF00072 Response regulator receiver domain 14 125 2.4E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 SUPERFAMILY SSF46689 225 274 9.86E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 225 267 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 SMART SM00342 188 271 4.9E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 Gene3D G3DSA:1.10.10.60 169 224 3.5E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22155 834695afc96be2bd0f169f9f907b5cb5 299 SUPERFAMILY SSF52172 6 137 3.84E-37 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 Gene3D G3DSA:3.90.180.10 1 145 1.9E-40 T 06-07-2017 IPR011032 GroES-like CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 SMART SM00829 10 326 2.5E-52 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 SUPERFAMILY SSF51735 112 294 8.46E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 SUPERFAMILY SSF50129 1 140 2.13E-32 T 06-07-2017 IPR011032 GroES-like CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.8E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 Pfam PF00107 Zinc-binding dehydrogenase 151 286 2.5E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS00140 a21d764a433f2092dbc96eea559ca9ce 333 Gene3D G3DSA:3.40.50.720 146 265 2.7E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 SUPERFAMILY SSF46548 830 948 1.12E-12 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Gene3D G3DSA:3.30.43.10 150 311 6.1E-32 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF02754 Cysteine-rich domain 1063 1152 3.0E-7 T 06-07-2017 IPR004017 Cysteine-rich domain CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF02754 Cysteine-rich domain 1188 1274 6.9E-4 T 06-07-2017 IPR004017 Cysteine-rich domain CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 SUPERFAMILY SSF55103 458 583 1.44E-15 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF02913 FAD linked oxidases, C-terminal domain 719 817 2.1E-17 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF02913 FAD linked oxidases, C-terminal domain 459 576 4.3E-4 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 918 929 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Gene3D G3DSA:1.10.1060.10 852 948 3.1E-13 T 06-07-2017 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF01565 FAD binding domain 195 340 7.1E-24 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 SUPERFAMILY SSF55103 713 820 7.36E-27 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF11880 Domain of unknown function (DUF3400) 1277 1321 2.3E-23 T 06-07-2017 IPR021817 Protein of unknown function DUF3400 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 SUPERFAMILY SSF56176 159 426 3.74E-52 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF12447 Protein of unknown function (DUF3683) 21 145 2.4E-51 T 06-07-2017 IPR022153 Protein of unknown function DUF3683 CAL12_RS25645 7aef3142adfc16bb2f8713a56f27fbf3 1321 Pfam PF13183 4Fe-4S dicluster domain 854 932 9.3E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS24365 7cb98da542445552c5d75c400f6eec06 403 Pfam PF07690 Major Facilitator Superfamily 23 365 4.4E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS24365 7cb98da542445552c5d75c400f6eec06 403 SUPERFAMILY SSF103473 14 401 8.63E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS24365 7cb98da542445552c5d75c400f6eec06 403 Gene3D G3DSA:1.20.1250.20 21 196 3.6E-18 T 06-07-2017 CAL12_RS09660 f5acb06edb87b2744956bb67a5742c4c 282 Pfam PF01435 Peptidase family M48 83 266 1.4E-38 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAL12_RS09660 f5acb06edb87b2744956bb67a5742c4c 282 Gene3D G3DSA:3.30.2010.10 77 167 8.8E-20 T 06-07-2017 CAL12_RS25400 22e60bcf091d096a561d6b2a7f33444f 201 Gene3D G3DSA:3.20.19.10 1 194 3.3E-46 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS25400 22e60bcf091d096a561d6b2a7f33444f 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 199 37.063 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS25400 22e60bcf091d096a561d6b2a7f33444f 201 SUPERFAMILY SSF52016 1 181 1.06E-54 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS25400 22e60bcf091d096a561d6b2a7f33444f 201 Pfam PF00694 Aconitase C-terminal domain 1 122 4.2E-32 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25400 22e60bcf091d096a561d6b2a7f33444f 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 187 1.1E-65 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.5E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 SUPERFAMILY SSF53850 88 296 1.45E-36 T 06-07-2017 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 Gene3D G3DSA:3.40.190.10 90 176 2.4E-18 T 06-07-2017 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 Pfam PF03466 LysR substrate binding domain 88 292 2.4E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 SUPERFAMILY SSF46785 1 81 2.61E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 Gene3D G3DSA:1.10.10.10 1 87 2.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02395 f700ed0dd252453dbb84c8918dbc6037 306 Gene3D G3DSA:3.40.190.10 177 261 1.6E-17 T 06-07-2017 CAL12_RS25560 bdaebe9c28f85a2264063dcd9402b853 269 Pfam PF08543 Phosphomethylpyrimidine kinase 12 263 1.3E-89 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAL12_RS25560 bdaebe9c28f85a2264063dcd9402b853 269 Gene3D G3DSA:3.40.1190.20 3 266 3.3E-101 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS25560 bdaebe9c28f85a2264063dcd9402b853 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 265 5.9E-91 T 06-07-2017 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS25560 bdaebe9c28f85a2264063dcd9402b853 269 SUPERFAMILY SSF53613 1 268 7.33E-77 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82693 566 676 2.93E-20 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82693 40 133 1.15E-25 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:1.20.1640.10 295 509 1.3E-61 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1039 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82866 811 1035 4.97E-45 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82693 138 184 8.2E-26 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82693 278 334 8.2E-26 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:3.30.70.1430 568 676 1.4E-23 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:3.30.2090.10 184 279 7.6E-23 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82866 300 501 2.22E-51 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 340 363 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 474 497 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 395 419 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 449 472 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 PRINTS PR00702 Acriflavin resistance protein family signature 367 388 2.1E-95 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:1.10.3850.10 819 1033 1.1E-55 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82714 185 275 6.28E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 SUPERFAMILY SSF82714 728 811 9.55E-21 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:3.30.70.1430 40 141 1.6E-31 T 06-07-2017 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Pfam PF00873 AcrB/AcrD/AcrF family 3 1031 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS22300 0f5c2e7aefad5f71eb8a127fcc7ab17b 1086 Gene3D G3DSA:3.30.2090.10 728 811 1.5E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 Gene3D G3DSA:3.40.50.2300 1 96 9.8E-33 T 06-07-2017 CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 Gene3D G3DSA:1.10.10.10 108 166 1.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 SUPERFAMILY SSF52172 1 160 4.2E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 SMART SM01012 105 160 2.5E-10 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 PIRSF PIRSF036382 1 167 1.3E-24 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator CAL12_RS07805 3d288fa10309400b563db22bd8a413e8 175 Pfam PF03861 ANTAR domain 108 160 7.3E-12 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 Pfam PF13411 MerR HTH family regulatory protein 1 67 9.9E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 SUPERFAMILY SSF46955 1 114 9.52E-33 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 Gene3D G3DSA:1.10.1660.10 1 55 5.0E-24 T 06-07-2017 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 128 1.4E-47 T 06-07-2017 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 Gene3D G3DSA:1.10.1660.10 56 132 1.0E-22 T 06-07-2017 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 SMART SM00422 1 70 4.2E-24 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 4.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 4.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11665 c2cba32297c9852cbbbb3babbc658145 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 4.7E-11 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS18220 85f68547da58e867075d02259417e794 469 Gene3D G3DSA:3.90.1380.10 1 82 2.3E-28 T 06-07-2017 IPR029144 Threonine synthase, N-terminal CAL12_RS18220 85f68547da58e867075d02259417e794 469 Gene3D G3DSA:3.40.50.1100 112 203 3.5E-6 T 06-07-2017 CAL12_RS18220 85f68547da58e867075d02259417e794 469 Pfam PF14821 Threonine synthase N terminus 2 79 1.7E-27 T 06-07-2017 IPR029144 Threonine synthase, N-terminal CAL12_RS18220 85f68547da58e867075d02259417e794 469 SUPERFAMILY SSF53686 1 465 1.55E-151 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS18220 85f68547da58e867075d02259417e794 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 107 345 9.0E-13 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS18220 85f68547da58e867075d02259417e794 469 Gene3D G3DSA:3.40.50.1100 204 440 3.6E-85 T 06-07-2017 CAL12_RS18220 85f68547da58e867075d02259417e794 469 TIGRFAM TIGR00260 thrC: threonine synthase 102 427 9.6E-72 T 06-07-2017 IPR004450 Threonine synthase-like CAL12_RS05720 04d90b15cca4810d4d5dfe13e1753728 126 Pfam PF00085 Thioredoxin 16 86 1.2E-10 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAL12_RS05720 04d90b15cca4810d4d5dfe13e1753728 126 Gene3D G3DSA:3.40.30.10 21 89 1.2E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS05720 04d90b15cca4810d4d5dfe13e1753728 126 SUPERFAMILY SSF52833 24 99 2.9E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14655 774b6aef74afaceb6c78ae5c3a3cc314 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 4.7E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14655 774b6aef74afaceb6c78ae5c3a3cc314 323 PIRSF PIRSF017082 2 322 6.3E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14655 774b6aef74afaceb6c78ae5c3a3cc314 323 SUPERFAMILY SSF53850 109 283 1.16E-15 T 06-07-2017 CAL12_RS14655 774b6aef74afaceb6c78ae5c3a3cc314 323 Gene3D G3DSA:3.40.190.10 179 222 9.5E-4 T 06-07-2017 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52980 1064 1097 2.9E-69 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52980 1127 1377 2.9E-69 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:1.10.3170.10 222 282 6.0E-38 T 06-07-2017 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:1.10.3170.10 325 462 6.0E-38 T 06-07-2017 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Pfam PF13361 UvrD-like helicase C-terminal domain 832 963 2.9E-12 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52540 438 611 3.19E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52540 183 267 3.19E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52540 648 969 3.19E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 SUPERFAMILY SSF52540 68 137 3.19E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 65 1376 1.0E-281 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1144 1360 1.4E-8 T 06-07-2017 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 63 1377 21.382 T 06-07-2017 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.40.50.300 464 566 3.0E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.40.50.300 185 215 3.0E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.40.50.300 67 139 3.0E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.40.50.300 567 721 1.2E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.40.50.300 874 1013 1.2E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:3.90.320.10 1056 1378 9.6E-86 T 06-07-2017 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Gene3D G3DSA:1.10.486.10 725 869 5.3E-45 T 06-07-2017 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Pfam PF00580 UvrD/REP helicase N-terminal domain 72 223 3.1E-24 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS01560 a2b235282ce693d18f9d130b81dd9886 1385 Pfam PF00580 UvrD/REP helicase N-terminal domain 433 551 1.0E-25 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 179 192 - T 06-07-2017 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 213 3.1E-85 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 PIRSF PIRSF000190 1 213 3.4E-80 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 213 38.3 T 06-07-2017 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 SUPERFAMILY SSF50475 6 213 2.5E-65 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 118 1.0E-28 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 169 213 3.7E-20 T 06-07-2017 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS05395 23374cf6204c3da0748581729b4980ba 213 Gene3D G3DSA:2.30.110.10 16 213 2.0E-84 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 Gene3D G3DSA:2.30.33.40 2 95 1.3E-38 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 06-07-2017 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 SUPERFAMILY SSF50129 1 94 1.7E-34 T 06-07-2017 IPR011032 GroES-like CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 SMART SM00883 2 94 4.6E-55 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.55 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 PRINTS PR00297 10kDa chaperonin signature 3 18 1.2E-32 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 PRINTS PR00297 10kDa chaperonin signature 60 72 1.2E-32 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 PRINTS PR00297 10kDa chaperonin signature 81 94 1.2E-32 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 PRINTS PR00297 10kDa chaperonin signature 25 46 1.2E-32 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS03105 94309c2a570668a3d122842d0772fb4a 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.8E-35 T 06-07-2017 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 SMART SM00895 101 229 4.1E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 SUPERFAMILY SSF46785 9 81 2.73E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 Gene3D G3DSA:1.20.120.530 95 239 1.1E-34 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 8.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 8.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 SUPERFAMILY SSF48008 98 237 2.25E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.3E-23 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 SMART SM00345 18 77 3.7E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 Pfam PF07729 FCD domain 102 228 1.6E-26 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS02755 f2098ef995940f450df0ac36a265a81c 240 Gene3D G3DSA:1.10.10.10 9 80 1.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Pfam PF00158 Sigma-54 interaction domain 346 513 4.5E-66 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SUPERFAMILY SSF55785 208 312 5.76E-11 T 06-07-2017 IPR000014 PAS domain CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 648 667 4.0E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 631 648 4.0E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 TIGRFAM TIGR02329 propionate_PrpR: propionate catabolism operon regulatory protein PrpR 25 663 2.1E-177 T 06-07-2017 IPR012704 Signal transduction response regulator, propionate catabolism, transcriptional regulator PrpR GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0005737|GO:0019629 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:3.40.50.300 343 519 5.6E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:3.40.50.2300 23 113 4.3E-29 T 06-07-2017 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SMART SM00091 218 285 4.9E-4 T 06-07-2017 IPR000014 PAS domain CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 215 265 1.7E-5 T 06-07-2017 IPR000014 PAS domain CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SUPERFAMILY SSF46689 562 663 3.54E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:3.30.450.20 214 314 2.2E-11 T 06-07-2017 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SMART SM00382 366 514 7.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SUPERFAMILY SSF159800 28 209 1.7E-42 T 06-07-2017 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Pfam PF02954 Bacterial regulatory protein, Fis family 628 663 3.8E-13 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 433 448 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 562 571 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 SUPERFAMILY SSF52540 345 579 1.02E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:1.10.10.60 567 663 7.4E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 370 383 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:1.10.8.60 520 566 9.0E-17 T 06-07-2017 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Pfam PF00989 PAS fold 219 265 1.6E-5 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Pfam PF06506 Propionate catabolism activator 49 212 5.7E-45 T 06-07-2017 IPR010524 Signal transduction response regulator, propionate catabolism activator, N-terminal GO:0000156|GO:0000160|GO:0003677|GO:0005524 CAL12_RS21860 c64673b60d91cbeb41aa178c1cb805f6 667 Gene3D G3DSA:3.40.50.10660 114 190 1.1E-27 T 06-07-2017 CAL12_RS14295 287a25a54ff9aa70a976e3d6bbf0d75d 244 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 62 216 7.9E-38 T 06-07-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 Gene3D G3DSA:1.10.1200.80 255 324 3.5E-23 T 06-07-2017 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 SUPERFAMILY SSF51395 10 321 3.26E-88 T 06-07-2017 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 1.1E-117 T 06-07-2017 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 PIRSF PIRSF006621 1 328 2.7E-103 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 Gene3D G3DSA:3.20.20.70 7 247 9.2E-83 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 Pfam PF01207 Dihydrouridine synthase (Dus) 14 313 3.1E-101 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAL12_RS05600 3eb21db4ce2786796ff4f468092f2327 341 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 324 49.932 T 06-07-2017 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 SUPERFAMILY SSF50615 10 94 2.75E-28 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 51.064 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 27 92 2.1E-16 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 7.9E-251 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Gene3D G3DSA:2.40.30.20 1 93 1.0E-33 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 PIRSF PIRSF039088 1 513 5.3E-239 T 06-07-2017 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Gene3D G3DSA:3.40.50.300 94 382 5.7E-116 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 SUPERFAMILY SSF52540 96 381 3.13E-95 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Gene3D G3DSA:1.20.150.20 383 509 3.4E-48 T 06-07-2017 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 SUPERFAMILY SSF47917 383 510 1.28E-46 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.3E-45 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.3E-75 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25805 e5d045d51a4a524333b5852ab9186aa5 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS03155 0ba2f3a60312cdbb02ce3d6eb7d97f35 321 Gene3D G3DSA:3.40.50.720 106 287 1.7E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03155 0ba2f3a60312cdbb02ce3d6eb7d97f35 321 SUPERFAMILY SSF51735 104 287 1.17E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03155 0ba2f3a60312cdbb02ce3d6eb7d97f35 321 SUPERFAMILY SSF52283 45 113 2.42E-7 T 06-07-2017 CAL12_RS03155 0ba2f3a60312cdbb02ce3d6eb7d97f35 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 286 2.3E-38 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Pfam PF00271 Helicase conserved C-terminal domain 450 553 7.8E-19 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SUPERFAMILY SSF52540 46 91 4.93E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SUPERFAMILY SSF52540 467 587 4.93E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SUPERFAMILY SSF52540 13 423 1.09E-133 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:3.40.50.300 287 347 5.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:3.40.50.300 15 98 5.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:3.40.50.300 397 418 5.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:3.30.2060.10 170 240 1.3E-9 T 06-07-2017 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:3.40.50.300 427 589 9.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SMART SM00487 18 433 3.2E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Pfam PF04851 Type III restriction enzyme, res subunit 49 141 3.5E-8 T 06-07-2017 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Gene3D G3DSA:4.10.860.10 629 669 1.5E-12 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SUPERFAMILY SSF46600 629 668 9.29E-9 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Hamap MF_00204 UvrABC system protein B [uvrB]. 12 668 43.144 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 Pfam PF12344 Ultra-violet resistance protein B 560 602 9.3E-20 T 06-07-2017 IPR024759 UvrB, YAD/RRR-motif-containing domain CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 SMART SM00490 468 554 1.9E-19 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS17190 13cdba09f02a2a159151fc16db0fdf23 675 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 14 666 0.0 T 06-07-2017 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Gene3D G3DSA:3.30.499.10 368 577 3.8E-64 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 146 159 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 371 385 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 170 178 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 495 508 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 277 290 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 291 304 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 201 214 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 215 230 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 PRINTS PR00415 Aconitase family signature 433 444 1.5E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Pfam PF00694 Aconitase C-terminal domain 693 825 4.2E-40 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Gene3D G3DSA:3.30.499.10 21 247 8.3E-76 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Gene3D G3DSA:3.20.19.10 638 899 2.3E-78 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Pfam PF00330 Aconitase family (aconitate hydratase) 69 564 2.7E-178 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 SUPERFAMILY SSF53732 4 619 2.49E-213 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 SUPERFAMILY SSF52016 637 899 3.73E-83 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAL12_RS08165 eb2192701978daf81d89d56f0f2f7767 901 Gene3D G3DSA:3.40.1060.10 248 366 8.4E-37 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 1.1E-94 T 06-07-2017 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Pfam PF00330 Aconitase family (aconitate hydratase) 472 814 8.1E-41 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 SUPERFAMILY SSF52016 162 370 1.43E-66 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Gene3D G3DSA:3.30.499.10 403 520 1.0E-62 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 PIRSF PIRSF036687 1 859 0.0 T 06-07-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Gene3D G3DSA:3.20.19.10 163 359 2.7E-89 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Gene3D G3DSA:3.40.1060.10 521 683 4.0E-86 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Pfam PF11791 Aconitate B N-terminal domain 5 156 3.9E-63 T 06-07-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 SUPERFAMILY SSF74778 1 160 1.96E-65 T 06-07-2017 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 SUPERFAMILY SSF53732 377 853 6.28E-145 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 Gene3D G3DSA:3.30.499.10 684 859 2.1E-52 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 06-07-2017 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 CAL12_RS19410 ae5406a12f82a88d18601b71360cf2d8 861 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.8E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 Pfam PF03466 LysR substrate binding domain 95 286 4.3E-24 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 Gene3D G3DSA:1.10.10.10 9 85 2.1E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 SUPERFAMILY SSF53850 95 289 6.88E-28 T 06-07-2017 CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 Gene3D G3DSA:3.40.190.10 98 180 5.1E-14 T 06-07-2017 CAL12_RS04445 f348356a7a3bc9c524a77ae5a5f51e0f 295 SUPERFAMILY SSF46785 7 117 1.82E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 SUPERFAMILY SSF53850 92 295 3.8E-39 T 06-07-2017 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Pfam PF03466 LysR substrate binding domain 99 297 6.2E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Gene3D G3DSA:1.10.10.10 2 88 2.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 SUPERFAMILY SSF46785 5 86 4.52E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Gene3D G3DSA:3.40.190.10 273 296 1.3E-27 T 06-07-2017 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Gene3D G3DSA:3.40.190.10 92 174 1.3E-27 T 06-07-2017 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Gene3D G3DSA:3.40.190.10 175 268 4.2E-27 T 06-07-2017 CAL12_RS12940 50eb2b0946d6582d680c5db3d4232e18 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 8.2E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 Gene3D G3DSA:3.40.190.10 26 105 9.1E-38 T 06-07-2017 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 Gene3D G3DSA:3.40.190.10 214 252 9.1E-38 T 06-07-2017 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 Gene3D G3DSA:3.40.190.10 106 196 3.5E-18 T 06-07-2017 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 SMART SM00062 27 254 2.0E-52 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 SUPERFAMILY SSF53850 2 252 1.76E-64 T 06-07-2017 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 SMART SM00079 27 252 0.0021 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAL12_RS01335 15796256483b5c232c77c62d2bd993c3 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 252 1.1E-58 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14100 19e66dc051502b813e7c08df22792cd6 229 SUPERFAMILY SSF110857 47 161 1.27E-10 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS14100 19e66dc051502b813e7c08df22792cd6 229 Pfam PF04752 ChaC-like protein 47 211 7.9E-45 T 06-07-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 CAL12_RS14100 19e66dc051502b813e7c08df22792cd6 229 Gene3D G3DSA:3.10.490.10 42 207 1.9E-33 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 Pfam PF03466 LysR substrate binding domain 88 291 7.5E-48 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 SUPERFAMILY SSF46785 1 85 4.02E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 SUPERFAMILY SSF53850 89 291 1.63E-43 T 06-07-2017 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 Gene3D G3DSA:1.10.10.10 1 85 1.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 Gene3D G3DSA:3.40.190.10 175 265 5.2E-32 T 06-07-2017 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.8E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21515 9f393be32d2030bb4bd22c231b06adc4 293 Gene3D G3DSA:3.40.190.10 89 174 1.1E-31 T 06-07-2017 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 SUPERFAMILY SSF46689 259 310 1.84E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 Gene3D G3DSA:1.10.10.60 205 260 6.0E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 Gene3D G3DSA:1.10.10.60 261 311 1.6E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 Pfam PF12833 Helix-turn-helix domain 229 308 7.0E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 Pfam PF12852 Cupin 6 189 2.1E-39 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 SMART SM00342 223 306 7.3E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21850 81efce51b89c690a49020d2f2c775241 319 SUPERFAMILY SSF46689 206 254 2.04E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 Gene3D G3DSA:3.40.605.10 15 273 9.4E-105 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 SUPERFAMILY SSF53720 14 487 2.62E-172 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 35 481 3.1E-221 T 06-07-2017 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 287 298 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 Gene3D G3DSA:3.40.309.10 274 458 5.4E-71 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS12540 e979b219e2e21471370689c3a3e54b08 489 Pfam PF00171 Aldehyde dehydrogenase family 24 481 1.4E-174 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 309 77.159 T 06-07-2017 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 306 1.2E-45 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 308 3.5E-110 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 9.3E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 273 296 9.3E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 9.3E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 270 9.3E-28 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 287 298 7.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 225 235 7.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 7.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 7.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 7.9E-30 T 06-07-2017 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 151 8.0E-51 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 Gene3D G3DSA:3.40.50.1370 149 295 1.9E-54 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 Gene3D G3DSA:3.40.50.1370 11 148 2.6E-57 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS17520 976b0e1451b982a7cb21391901701d4b 313 SUPERFAMILY SSF53671 11 308 5.89E-102 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 Gene3D G3DSA:2.60.40.1180 598 692 4.3E-13 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 Gene3D G3DSA:2.60.40.10 11 162 5.1E-54 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 SUPERFAMILY SSF51011 598 692 2.45E-15 T 06-07-2017 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 SMART SM00642 143 577 3.8E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 16 104 2.2E-16 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 Gene3D G3DSA:3.20.20.80 163 584 6.0E-111 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 SUPERFAMILY SSF81296 11 157 7.84E-47 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 SUPERFAMILY SSF51445 144 478 1.36E-120 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 SUPERFAMILY SSF51445 507 584 1.36E-120 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 Pfam PF00128 Alpha amylase, catalytic domain 199 283 2.2E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16160 2dcc8aba9cc844de72ca8c9c8001e719 702 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 12 692 0.0 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 SUPERFAMILY SSF53474 40 300 2.45E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 Pfam PF12697 Alpha/beta hydrolase family 66 291 2.1E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 Gene3D G3DSA:3.40.50.1820 35 299 2.5E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 147 160 4.8E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 133 146 4.8E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 104 4.8E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13260 00f3779ba41e2c74beadc1cdf7252506 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 246 260 4.8E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 SUPERFAMILY SSF55874 10 222 5.11E-67 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 Hamap MF_00505 Chaperone protein HtpG [htpG]. 8 633 32.819 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 Gene3D G3DSA:3.30.565.10 11 247 2.3E-83 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 SMART SM00387 33 190 5.2E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 178 195 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 99 116 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 32 54 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 81 98 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 11 31 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 126 148 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PRINTS PR00775 90kDa heat shock protein signature 196 214 1.5E-60 T 06-07-2017 IPR020575 Heat shock protein Hsp90, N-terminal CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 188 3.8E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 PIRSF PIRSF002583 1 635 6.2E-219 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 SUPERFAMILY SSF54211 240 495 2.12E-99 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 Pfam PF00183 Hsp90 protein 223 633 7.3E-133 T 06-07-2017 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 SUPERFAMILY SSF110942 521 633 3.79E-35 T 06-07-2017 CAL12_RS02210 8f13202ae672b9957774c3227e423e45 635 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 31 40 - T 06-07-2017 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CAL12_RS01910 3efccc613c43319f0b05fe1b9a6d8c13 207 SUPERFAMILY SSF55144 32 204 1.83E-34 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAL12_RS01910 3efccc613c43319f0b05fe1b9a6d8c13 207 Pfam PF02834 LigT like Phosphoesterase 39 115 4.4E-14 T 06-07-2017 IPR014051 Phosphoesterase, HXTX CAL12_RS01910 3efccc613c43319f0b05fe1b9a6d8c13 207 Gene3D G3DSA:3.90.1140.10 31 204 4.6E-34 T 06-07-2017 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase CAL12_RS01910 3efccc613c43319f0b05fe1b9a6d8c13 207 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 31 207 16.832 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAL12_RS01910 3efccc613c43319f0b05fe1b9a6d8c13 207 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 31 205 1.0E-26 T 06-07-2017 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 Gene3D G3DSA:3.30.950.10 138 254 4.1E-35 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 SUPERFAMILY SSF53790 30 251 1.57E-71 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 31 305 1.7E-67 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 Gene3D G3DSA:3.40.1010.10 30 137 2.6E-14 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 30 254 32.903 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 108 119 - T 06-07-2017 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 30 232 6.2E-28 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS01675 3b4b2e6938cd3f9ef9a7ce07f5711d95 310 PIRSF PIRSF005917 18 310 3.1E-91 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 Gene3D G3DSA:1.10.287.1040 20 79 4.1E-25 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 Pfam PF02609 Exonuclease VII small subunit 22 72 9.7E-21 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 SUPERFAMILY SSF116842 19 82 9.55E-20 T 06-07-2017 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 21 75 4.2E-22 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 21 81 15.179 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS18310 886e39515eb383764ae156db0d95d6bf 93 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 22 62 9.0E-13 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Gene3D G3DSA:2.40.110.10 119 219 3.6E-30 T 06-07-2017 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 217 3.7E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Gene3D G3DSA:1.20.140.10 220 384 2.0E-54 T 06-07-2017 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 SUPERFAMILY SSF47203 230 383 9.5E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 SUPERFAMILY SSF56645 4 229 1.96E-60 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 113 3.0E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 363 5.4E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS00055 6684ed85722e1eabdbbea3febd90d20e 385 Gene3D G3DSA:1.10.540.10 5 115 6.0E-30 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 SMART SM00382 365 534 4.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 SMART SM00382 46 258 2.7E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 Gene3D G3DSA:3.40.50.300 21 290 9.6E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 Gene3D G3DSA:3.40.50.300 341 551 1.8E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 Pfam PF00005 ABC transporter 38 204 1.1E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 Pfam PF00005 ABC transporter 357 489 9.6E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 SUPERFAMILY SSF52540 26 257 6.83E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 SUPERFAMILY SSF52540 317 544 4.7E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10935 b0edbc4ae56c07fff87817a07405bcfc 554 Pfam PF12848 ABC transporter 244 331 1.2E-17 T 06-07-2017 IPR032781 ABC-transporter extension domain CAL12_RS18795 8b8eeab07b13b917680d1ac135128e25 552 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 9 552 6.4E-293 T 06-07-2017 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 CAL12_RS18795 8b8eeab07b13b917680d1ac135128e25 552 SUPERFAMILY SSF100950 229 491 2.86E-20 T 06-07-2017 CAL12_RS18795 8b8eeab07b13b917680d1ac135128e25 552 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 10 552 3.7E-298 T 06-07-2017 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 CAL12_RS18795 8b8eeab07b13b917680d1ac135128e25 552 Gene3D G3DSA:3.40.1080.10 43 232 3.2E-7 T 06-07-2017 CAL12_RS18795 8b8eeab07b13b917680d1ac135128e25 552 SUPERFAMILY SSF100950 41 281 1.38E-31 T 06-07-2017 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SUPERFAMILY SSF55874 249 419 1.31E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 395 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 414 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 1.1E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SUPERFAMILY SSF47384 184 256 1.96E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Pfam PF00072 Response regulator receiver domain 440 546 3.3E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SUPERFAMILY SSF52172 439 554 8.68E-27 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Gene3D G3DSA:3.30.565.10 245 415 1.4E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Gene3D G3DSA:3.40.50.2300 438 554 9.7E-30 T 06-07-2017 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SMART SM00388 194 259 2.5E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 301 414 8.5E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Gene3D G3DSA:1.10.287.130 189 244 5.5E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SMART SM00387 300 417 1.2E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 257 1.0E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 SMART SM00448 438 549 2.5E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13485 e1a05c1303e6ac87c5fe4865f61215c9 562 Gene3D G3DSA:3.40.50.2300 26 137 6.6E-4 T 06-07-2017 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 SUPERFAMILY SSF54292 2 78 1.02E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 SUPERFAMILY SSF47741 73 149 3.53E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 Gene3D G3DSA:3.10.20.30 3 74 1.1E-24 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 Pfam PF01799 [2Fe-2S] binding domain 73 144 2.3E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 58 5.9E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS14730 847b320802b3e3095a89db09b81cd7a5 152 Gene3D G3DSA:1.10.150.120 75 150 4.3E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03405 ef0bea6b91181c65a314a17a6869071f 293 SUPERFAMILY SSF51735 7 241 6.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03405 ef0bea6b91181c65a314a17a6869071f 293 Pfam PF05368 NmrA-like family 7 226 2.6E-21 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAL12_RS03405 ef0bea6b91181c65a314a17a6869071f 293 Gene3D G3DSA:3.40.50.720 5 223 1.9E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16825 a9186a3f050a8b446628e345f546b322 163 Gene3D G3DSA:3.30.310.70 48 161 2.1E-21 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAL12_RS16825 a9186a3f050a8b446628e345f546b322 163 SUPERFAMILY SSF103247 48 161 1.96E-17 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAL12_RS16825 a9186a3f050a8b446628e345f546b322 163 Pfam PF03625 Domain of unknown function DUF302 88 131 1.8E-5 T 06-07-2017 IPR005180 Domain of unknown function DUF302 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 SUPERFAMILY SSF49503 102 258 7.57E-46 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Gene3D G3DSA:2.60.40.420 102 234 5.0E-43 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 SUPERFAMILY SSF46626 235 314 9.26E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 21 214 1.1E-51 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Gene3D G3DSA:1.10.287.90 18 92 3.1E-9 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Gene3D G3DSA:1.10.760.10 235 314 9.2E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 199 9.9E-19 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Pfam PF00034 Cytochrome c 225 314 2.8E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 SUPERFAMILY SSF81464 16 97 4.58E-9 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 150 198 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14895 c06f75092d880bfc38d0f1e8fb8da599 323 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 16 87 1.4E-4 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 SMART SM00895 76 203 2.4E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 SMART SM00345 8 66 1.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 Gene3D G3DSA:1.10.10.10 7 67 6.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 66 1.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 Gene3D G3DSA:1.20.120.530 72 212 2.7E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 Pfam PF07729 FCD domain 76 202 7.7E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 SUPERFAMILY SSF46785 6 70 7.07E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01160 5c1d87bba7976e614b109dbe307d003d 220 SUPERFAMILY SSF48008 73 210 7.06E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 SUPERFAMILY SSF53474 8 256 9.02E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 Gene3D G3DSA:3.40.50.1820 8 257 1.2E-56 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 Pfam PF00561 alpha/beta hydrolase fold 21 246 7.3E-28 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 203 217 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS12505 3f0f1874553f72269ec03539642ff6fc 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 1.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS10155 f290772ceeeb8c4adc4feab1a1dca003 413 Gene3D G3DSA:3.50.50.60 283 326 1.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10155 f290772ceeeb8c4adc4feab1a1dca003 413 Gene3D G3DSA:3.50.50.60 3 185 1.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10155 f290772ceeeb8c4adc4feab1a1dca003 413 Pfam PF01494 FAD binding domain 5 181 4.2E-13 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS10155 f290772ceeeb8c4adc4feab1a1dca003 413 SUPERFAMILY SSF51905 287 392 6.24E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10155 f290772ceeeb8c4adc4feab1a1dca003 413 SUPERFAMILY SSF51905 3 180 6.24E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 SUPERFAMILY SSF56954 70 485 3.14E-109 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 SUPERFAMILY SSF56954 4 39 3.14E-109 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Pfam PF02321 Outer membrane efflux protein 295 481 6.8E-25 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Pfam PF02321 Outer membrane efflux protein 79 271 9.8E-26 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Gene3D G3DSA:1.20.1600.10 159 329 3.3E-104 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Gene3D G3DSA:1.20.1600.10 68 105 3.3E-104 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Gene3D G3DSA:1.20.1600.10 371 485 3.3E-104 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Gene3D G3DSA:2.20.200.10 330 360 3.4E-14 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 Gene3D G3DSA:2.20.200.10 115 158 3.4E-14 T 06-07-2017 CAL12_RS01915 57563dca42eab39714b0e5076f7480ab 521 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 484 4.3E-128 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS03935 6d876793029df9862f79c430eda203af 303 SUPERFAMILY SSF46785 2 84 6.35E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03935 6d876793029df9862f79c430eda203af 303 Gene3D G3DSA:3.40.190.10 180 265 1.3E-15 T 06-07-2017 CAL12_RS03935 6d876793029df9862f79c430eda203af 303 Gene3D G3DSA:3.40.190.10 101 179 2.7E-15 T 06-07-2017 CAL12_RS03935 6d876793029df9862f79c430eda203af 303 Gene3D G3DSA:1.10.10.10 2 81 6.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03935 6d876793029df9862f79c430eda203af 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.5E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03935 6d876793029df9862f79c430eda203af 303 Pfam PF03466 LysR substrate binding domain 89 297 5.2E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03935 6d876793029df9862f79c430eda203af 303 SUPERFAMILY SSF53850 89 300 4.5E-34 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 97 1.6E-24 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF00037 4Fe-4S binding domain 211 226 3.7E-5 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.40.50.740 567 769 2.6E-88 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.40.50.740 297 374 2.6E-88 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SMART SM00926 240 294 3.1E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 143 9.6E-17 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:2.20.25.90 251 295 2.9E-19 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 920 1.4E-284 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.30.70.20 220 250 3.1E-4 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 170 181 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SUPERFAMILY SSF54862 96 233 1.72E-37 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SUPERFAMILY SSF50692 768 922 3.39E-41 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SUPERFAMILY SSF53706 241 768 1.31E-193 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.10.20.30 19 75 1.1E-8 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:2.40.40.20 770 922 4.0E-43 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.30.70.20 154 219 4.2E-15 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 241 292 2.8E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Gene3D G3DSA:3.40.228.10 375 566 1.1E-55 T 06-07-2017 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SMART SM00929 104 144 9.9E-19 T 06-07-2017 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF00384 Molybdopterin oxidoreductase 297 728 2.0E-72 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 Pfam PF01568 Molydopterin dinucleotide binding domain 812 916 1.3E-28 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 PIRSF PIRSF036643 18 952 0.0 T 06-07-2017 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 CAL12_RS23960 ddd861d145b59c626b46136537fa7a8f 954 SUPERFAMILY SSF54292 22 95 2.85E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 36.458 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 SUPERFAMILY SSF52418 78 339 6.54E-95 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 6.3E-10 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 Gene3D G3DSA:3.40.1030.10 75 339 1.8E-104 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 336 2.8E-124 T 06-07-2017 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 Gene3D G3DSA:1.20.970.10 7 72 2.4E-24 T 06-07-2017 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 Pfam PF00591 Glycosyl transferase family, a/b domain 78 327 8.1E-92 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS26115 18911cc76b3a14d682e6b833f7eaebe9 341 SUPERFAMILY SSF47648 5 71 3.01E-15 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 325 1.0E-34 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 22 315 1.3E-107 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Gene3D G3DSA:3.30.1360.10 6 62 2.2E-10 T 06-07-2017 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 307 8.7E-25 T 06-07-2017 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 SUPERFAMILY SSF47789 250 322 1.07E-26 T 06-07-2017 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 SUPERFAMILY SSF56553 51 175 5.49E-42 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 316 35.525 T 06-07-2017 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Gene3D G3DSA:2.170.120.12 63 174 8.8E-42 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 224 1.1E-23 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Gene3D G3DSA:1.10.150.20 246 322 9.5E-36 T 06-07-2017 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 151 5.8E-24 T 06-07-2017 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 SMART SM00662 21 231 9.7E-101 T 06-07-2017 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 SUPERFAMILY SSF55257 176 229 2.75E-32 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27495 f64c125df850c3f86b3ab358e765df98 328 SUPERFAMILY SSF55257 5 51 2.75E-32 T 06-07-2017 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 Pfam PF13378 Enolase C-terminal domain-like 161 366 4.4E-53 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 SMART SM00922 157 249 1.7E-18 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 SUPERFAMILY SSF51604 126 372 6.8E-61 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 113 138 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 SUPERFAMILY SSF54826 11 141 3.09E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 Gene3D G3DSA:3.30.390.10 10 144 3.0E-39 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 198 229 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 Gene3D G3DSA:3.20.20.120 145 372 2.1E-59 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00120 20bc57fa11c0df05ba675d0ec5f0f7ea 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 41 138 3.8E-17 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS16790 e23a878b51ad6b464e6ab8082e895b7b 285 Gene3D G3DSA:1.20.1250.20 95 271 6.9E-10 T 06-07-2017 CAL12_RS16790 e23a878b51ad6b464e6ab8082e895b7b 285 SUPERFAMILY SSF103473 32 274 1.44E-21 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 Gene3D G3DSA:2.40.160.10 11 347 5.6E-78 T 06-07-2017 IPR023614 Porin domain CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 Pfam PF13609 Gram-negative porin 2 321 9.3E-46 T 06-07-2017 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00184 Neisseria sp. porin signature 46 71 1.4E-5 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00184 Neisseria sp. porin signature 146 163 1.4E-5 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00184 Neisseria sp. porin signature 296 320 1.4E-5 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 SUPERFAMILY SSF56935 10 347 5.83E-72 T 06-07-2017 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 44 55 2.5E-7 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 299 316 2.5E-7 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 88 98 2.5E-7 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS09965 c31cae8d7090131c206efefbf52a2f52 347 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 147 158 2.5E-7 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.8E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 183 2.3E-24 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 Gene3D G3DSA:1.10.357.10 55 187 2.8E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 Gene3D G3DSA:1.10.10.60 7 54 1.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 SUPERFAMILY SSF48498 73 189 1.48E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16865 64c2fd8449a4ce90c7ce476ffe7b1d11 190 SUPERFAMILY SSF46689 7 66 1.9E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.803 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 9.0E-29 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.0E-27 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 Pfam PF01649 Ribosomal protein S20 2 84 3.5E-27 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 SUPERFAMILY SSF46992 3 86 3.53E-30 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS17480 d27ddd5f132c2d877320def71deef405 87 Gene3D G3DSA:1.20.58.110 1 86 2.8E-30 T 06-07-2017 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS09805 630f083528328371b001dca8f68a3289 331 Pfam PF00005 ABC transporter 29 186 1.7E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09805 630f083528328371b001dca8f68a3289 331 Gene3D G3DSA:3.40.50.300 8 259 1.1E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09805 630f083528328371b001dca8f68a3289 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 321 1.4E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS09805 630f083528328371b001dca8f68a3289 331 SMART SM00382 37 236 1.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09805 630f083528328371b001dca8f68a3289 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 304 4.3E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS09805 630f083528328371b001dca8f68a3289 331 SUPERFAMILY SSF52540 8 257 1.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26240 4dc735802e4caca1e200da8f8d567f45 415 SUPERFAMILY SSF55931 4 364 1.08E-101 T 06-07-2017 CAL12_RS26240 4dc735802e4caca1e200da8f8d567f45 415 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 288 5.3E-52 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS26240 4dc735802e4caca1e200da8f8d567f45 415 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 415 89.468 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS26240 4dc735802e4caca1e200da8f8d567f45 415 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 296 2.6E-87 T 06-07-2017 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS06215 c379709eb0f41225cb03febdd0281597 299 Gene3D G3DSA:2.60.200.30 144 264 5.2E-39 T 06-07-2017 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAL12_RS06215 c379709eb0f41225cb03febdd0281597 299 Hamap MF_00361 NAD kinase [nadK]. 4 288 32.252 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAL12_RS06215 c379709eb0f41225cb03febdd0281597 299 SUPERFAMILY SSF111331 5 290 5.63E-85 T 06-07-2017 IPR016064 NAD kinase/diacylglycerol kinase-like domain CAL12_RS06215 c379709eb0f41225cb03febdd0281597 299 Gene3D G3DSA:3.40.50.10330 3 143 6.3E-36 T 06-07-2017 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAL12_RS06215 c379709eb0f41225cb03febdd0281597 299 Pfam PF01513 ATP-NAD kinase 56 271 2.5E-54 T 06-07-2017 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 Gene3D G3DSA:1.20.120.530 75 211 1.2E-33 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 SUPERFAMILY SSF48008 77 201 1.1E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 5.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 SMART SM00895 81 199 3.5E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 Pfam PF07729 FCD domain 81 198 7.8E-28 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 SMART SM00345 13 71 5.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 Gene3D G3DSA:1.10.10.10 4 72 1.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08755 a35705c7b66adb51a7cadb6b7584067d 216 SUPERFAMILY SSF46785 8 75 8.78E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19965 4e6fc73cd01b464280702c1c37b92d26 240 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 5 239 1.7E-43 T 06-07-2017 IPR012807 Anti-sigma factor ChrR, putative CAL12_RS19965 4e6fc73cd01b464280702c1c37b92d26 240 SUPERFAMILY SSF51182 123 225 6.93E-11 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS19965 4e6fc73cd01b464280702c1c37b92d26 240 Gene3D G3DSA:2.60.120.10 135 226 4.1E-7 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS19965 4e6fc73cd01b464280702c1c37b92d26 240 Pfam PF12973 ChrR Cupin-like domain 154 215 1.2E-8 T 06-07-2017 IPR025979 ChrR-like cupin domain CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SMART SM00260 512 652 7.3E-12 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SMART SM00073 8 105 1.8E-15 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SUPERFAMILY SSF47226 8 112 2.49E-23 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Gene3D G3DSA:3.40.50.2300 677 801 8.6E-34 T 06-07-2017 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Gene3D G3DSA:1.20.120.160 8 142 8.5E-29 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 519 1.3E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Pfam PF01627 Hpt domain 11 100 3.2E-13 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Pfam PF01584 CheW-like domain 526 655 3.7E-17 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Pfam PF00072 Response regulator receiver domain 682 794 7.3E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SUPERFAMILY SSF52172 677 800 4.41E-32 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Gene3D G3DSA:2.30.30.40 520 541 2.2E-10 T 06-07-2017 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Gene3D G3DSA:2.30.30.40 607 651 2.2E-10 T 06-07-2017 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 Gene3D G3DSA:3.30.565.10 339 518 3.8E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SUPERFAMILY SSF55874 336 518 3.01E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 517 6.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 498 6.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 6.5E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SMART SM00448 680 794 1.3E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SMART SM00387 377 520 9.4E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19070 e346cbe980fe5ad27d8cf0ef74b8bbb1 803 SUPERFAMILY SSF50341 519 652 2.09E-21 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS15185 1ff7ee6d92cdf46117420e97add49ba3 159 SMART SM00347 48 149 1.6E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS15185 1ff7ee6d92cdf46117420e97add49ba3 159 ProSitePatterns PS01117 MarR-type HTH domain signature. 89 123 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS15185 1ff7ee6d92cdf46117420e97add49ba3 159 Pfam PF12802 MarR family 54 113 3.7E-14 T 06-07-2017 CAL12_RS15185 1ff7ee6d92cdf46117420e97add49ba3 159 SUPERFAMILY SSF46785 26 141 1.69E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15185 1ff7ee6d92cdf46117420e97add49ba3 159 Gene3D G3DSA:1.10.10.10 31 141 2.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 Gene3D G3DSA:1.10.40.50 256 316 4.6E-24 T 06-07-2017 CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 28 319 34.214 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 Pfam PF03193 Protein of unknown function, DUF258 82 254 2.6E-46 T 06-07-2017 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 SUPERFAMILY SSF50249 28 85 3.43E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 Gene3D G3DSA:3.40.50.300 97 253 7.4E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 Gene3D G3DSA:2.40.50.140 28 84 5.8E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 SUPERFAMILY SSF52540 99 315 3.44E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18705 6d101626aeb2663930a2936a7d35bf1d 321 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 63 312 7.0E-57 T 06-07-2017 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 Gene3D G3DSA:3.30.450.40 85 235 6.1E-32 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 SUPERFAMILY SSF46785 20 92 3.25E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 Pfam PF09339 IclR helix-turn-helix domain 22 73 2.3E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 Gene3D G3DSA:1.10.10.10 11 80 7.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 Pfam PF01614 Bacterial transcriptional regulator 170 220 7.9E-5 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 SUPERFAMILY SSF55781 77 235 1.77E-29 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS24190 95050e8de69780f3ab06582fe922316e 242 SMART SM00346 20 109 9.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS07780 c61ff839994dc970a977fdd7a8024d35 387 SUPERFAMILY SSF53822 28 373 2.71E-88 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS07780 c61ff839994dc970a977fdd7a8024d35 387 Gene3D G3DSA:3.40.50.2300 144 326 9.5E-54 T 06-07-2017 CAL12_RS07780 c61ff839994dc970a977fdd7a8024d35 387 Pfam PF13458 Periplasmic binding protein 28 366 2.2E-77 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS07780 c61ff839994dc970a977fdd7a8024d35 387 Gene3D G3DSA:3.40.50.2300 26 111 9.2E-6 T 06-07-2017 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 Gene3D G3DSA:1.10.3080.10 10 424 9.5E-61 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 SUPERFAMILY SSF81340 5 429 1.83E-79 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 Pfam PF00654 Voltage gated chloride channel 64 414 8.0E-70 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 77 94 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 364 380 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 167 186 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 111 130 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 334 354 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS17420 017e8ab3b3f075165a366180cdb293e3 453 PRINTS PR00762 Chloride channel signature 382 401 5.3E-27 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Pfam PF08521 Two-component sensor kinase N-terminal 39 191 2.1E-31 T 06-07-2017 IPR013727 Two-component sensor kinase, N-terminal CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 SUPERFAMILY SSF47384 255 337 1.28E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 335 3.5E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Gene3D G3DSA:1.10.287.130 265 322 2.0E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 483 5.6E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 443 5.6E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 SUPERFAMILY SSF55874 337 509 4.32E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 393 507 3.3E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Gene3D G3DSA:3.30.565.10 323 512 8.2E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 Pfam PF00672 HAMP domain 207 260 1.4E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 SMART SM00388 272 337 4.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22600 7fe50605cbfaa91cbd2d48007e919ac0 525 SMART SM00387 392 510 5.6E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 181 281 1.2E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 3.7E-42 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 SUPERFAMILY SSF55447 178 283 5.49E-22 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 SUPERFAMILY SSF56176 1 173 1.2E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 Gene3D G3DSA:3.30.43.10 1 53 1.7E-18 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 Gene3D G3DSA:3.30.390.50 178 286 3.1E-26 T 06-07-2017 CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 Gene3D G3DSA:3.30.465.10 58 173 3.6E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS00195 8bccf77de20e5a9f27377f7d8dc4b464 296 SMART SM01092 180 281 5.4E-24 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 SUPERFAMILY SSF52540 63 349 2.77E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 Pfam PF00271 Helicase conserved C-terminal domain 224 328 1.1E-24 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 142 150 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 SMART SM00487 8 211 5.7E-61 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 Gene3D G3DSA:3.40.50.300 201 356 1.7E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 Pfam PF00270 DEAD/DEAH box helicase 13 184 9.6E-49 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 SMART SM00490 247 328 2.7E-29 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS00700 e1f59fa4a8bdfe7b84a2b4ecf59d8bca 357 Gene3D G3DSA:3.40.50.300 1 200 1.2E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SUPERFAMILY SSF141868 802 1048 5.36E-90 T 06-07-2017 IPR001633 EAL domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00267 612 785 2.9E-64 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Gene3D G3DSA:3.30.450.20 507 611 1.5E-18 T 06-07-2017 CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Pfam PF00563 EAL domain 803 1036 1.6E-74 T 06-07-2017 IPR001633 EAL domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Gene3D G3DSA:3.20.20.450 799 1048 1.1E-98 T 06-07-2017 IPR001633 EAL domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Pfam PF13426 PAS domain 509 611 7.0E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SUPERFAMILY SSF55785 487 610 6.46E-19 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 621 783 9.4E-42 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SUPERFAMILY SSF158472 320 368 2.88E-8 T 06-07-2017 CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Gene3D G3DSA:3.30.70.270 624 793 1.5E-56 T 06-07-2017 CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00304 319 372 9.4E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 495 618 6.7E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Pfam PF00672 HAMP domain 302 368 1.4E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00086 570 612 0.0062 T 06-07-2017 IPR001610 PAC motif CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00091 498 564 0.0059 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00091 385 453 16.0 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SMART SM00052 795 1041 2.1E-118 T 06-07-2017 IPR001633 EAL domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Pfam PF13188 PAS domain 388 420 0.093 T 06-07-2017 IPR000014 PAS domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 Pfam PF00990 Diguanylate cyclase, GGDEF domain 623 781 3.6E-49 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19805 2343b476a4520709ea06c90cfcd58779 1058 SUPERFAMILY SSF55073 628 787 1.65E-48 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 SUPERFAMILY SSF55781 27 160 6.76E-27 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 SMART SM00267 151 323 1.1E-47 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 SMART SM00065 26 168 1.1E-14 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 Gene3D G3DSA:3.30.70.270 166 322 2.4E-47 T 06-07-2017 CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 SUPERFAMILY SSF55073 169 322 5.96E-43 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 163 322 1.2E-42 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 Pfam PF00990 Diguanylate cyclase, GGDEF domain 164 320 4.6E-41 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 Pfam PF01590 GAF domain 28 158 6.1E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS04755 9b741afc54ef234528c5d610af8573de 323 Gene3D G3DSA:3.30.450.40 26 158 1.4E-12 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 SUPERFAMILY SSF52540 13 258 8.84E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 Gene3D G3DSA:3.40.50.300 12 260 2.9E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 Pfam PF00005 ABC transporter 29 188 1.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 PIRSF PIRSF039085 10 264 3.9E-102 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS25510 44381eea6421a9be73e91fd041002a0e 274 SMART SM00382 38 236 1.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 274 302 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 SUPERFAMILY SSF52440 33 125 2.4E-30 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 33 331 1.0E-95 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 32 332 35.808 T 06-07-2017 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 92 103 - T 06-07-2017 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Gene3D G3DSA:3.30.1490.20 135 202 9.4E-20 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 SUPERFAMILY SSF56059 125 328 2.12E-57 T 06-07-2017 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Pfam PF01820 D-ala D-ala ligase N-terminus 33 115 4.4E-22 T 06-07-2017 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Gene3D G3DSA:3.30.470.20 203 331 5.6E-51 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Gene3D G3DSA:3.30.470.20 114 132 5.6E-51 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Pfam PF07478 D-ala D-ala ligase C-terminus 133 328 5.0E-55 T 06-07-2017 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22400 4eab3189e80f67bcab06a07249653f52 342 Gene3D G3DSA:3.40.50.20 33 113 4.5E-28 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 Gene3D G3DSA:3.20.20.140 293 366 9.7E-9 T 06-07-2017 CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 Gene3D G3DSA:2.30.40.10 16 104 2.2E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 Pfam PF07969 Amidohydrolase family 155 372 1.3E-7 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 SUPERFAMILY SSF51556 61 108 1.41E-14 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 SUPERFAMILY SSF51556 148 350 1.41E-14 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 PIRSF PIRSF038971 12 384 2.6E-103 T 06-07-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 SUPERFAMILY SSF51338 350 389 2.81E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05130 fb784552c51781d9e2abd4af0c9e2a00 398 SUPERFAMILY SSF51338 25 60 2.81E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 2.8E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 2.8E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 SMART SM00895 94 218 3.3E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 Gene3D G3DSA:1.10.10.10 16 82 9.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 SMART SM00345 26 84 1.3E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 Pfam PF07729 FCD domain 96 217 1.0E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 SUPERFAMILY SSF46785 19 88 2.69E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 Gene3D G3DSA:1.20.120.530 87 228 2.0E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 SUPERFAMILY SSF48008 91 225 5.49E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS24220 0ec241ad00d165a3f0278e6971f8bebe 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 82 4.0E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 SUPERFAMILY SSF53850 32 262 1.09E-46 T 06-07-2017 CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 5.7E-30 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 SMART SM00062 41 271 1.8E-46 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 Gene3D G3DSA:3.40.190.10 39 131 3.1E-17 T 06-07-2017 CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 Gene3D G3DSA:3.40.190.10 233 261 3.1E-17 T 06-07-2017 CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 Gene3D G3DSA:3.40.190.10 132 232 8.7E-13 T 06-07-2017 CAL12_RS26400 faf7a92073a1ba257105bf3f9969b067 347 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 64 77 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 PIRSF PIRSF001455 18 356 3.0E-107 T 06-07-2017 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 Gene3D G3DSA:3.40.50.1970 3 171 1.3E-64 T 06-07-2017 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 SUPERFAMILY SSF56796 9 354 1.96E-112 T 06-07-2017 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 Gene3D G3DSA:1.20.1090.10 172 354 1.2E-64 T 06-07-2017 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 Pfam PF01761 3-dehydroquinate synthase 66 323 9.6E-107 T 06-07-2017 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 350 1.2E-118 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAL12_RS27425 a555d4a42a16128e09d925935db1596a 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 356 41.217 T 06-07-2017 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 Gene3D G3DSA:3.30.390.50 180 285 9.6E-28 T 06-07-2017 CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 SUPERFAMILY SSF55447 182 285 1.44E-21 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 SUPERFAMILY SSF56176 1 175 1.23E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 SMART SM01092 182 283 8.1E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 Gene3D G3DSA:3.30.43.10 1 55 7.9E-17 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 Gene3D G3DSA:3.30.465.10 59 175 2.5E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 184 282 4.1E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS00170 31f2535bc68590ef695f6096ca9d2368 295 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 175 1.1E-38 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 238 247 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 Gene3D G3DSA:1.10.8.60 199 247 1.2E-21 T 06-07-2017 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 SUPERFAMILY SSF46689 236 329 2.58E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 Gene3D G3DSA:3.40.50.300 26 198 2.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 SMART SM00382 46 189 6.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 50 63 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 Pfam PF00158 Sigma-54 interaction domain 28 192 2.2E-68 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 SUPERFAMILY SSF52540 28 257 1.52E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 112 127 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 Pfam PF02954 Bacterial regulatory protein, Fis family 292 328 9.3E-9 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS17640 6723c844e47197fa8f58de9bc9f95b65 338 Gene3D G3DSA:1.10.10.60 248 329 2.0E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 Pfam PF13602 Zinc-binding dehydrogenase 192 332 6.7E-23 T 06-07-2017 CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 148 169 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 Gene3D G3DSA:3.90.180.10 1 157 5.5E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 335 2.3E-158 T 06-07-2017 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 SUPERFAMILY SSF50129 1 144 2.74E-33 T 06-07-2017 IPR011032 GroES-like CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 SUPERFAMILY SSF51735 116 285 4.29E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 Gene3D G3DSA:3.40.50.720 158 245 2.6E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 90 1.4E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS16210 d562aa8f55300ae7f3bffda8a13e03d8 337 SMART SM00829 10 332 2.6E-11 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 Pfam PF07690 Major Facilitator Superfamily 31 257 3.6E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 Gene3D G3DSA:1.20.1250.20 25 214 1.7E-35 T 06-07-2017 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 Gene3D G3DSA:1.20.1250.20 232 403 1.0E-25 T 06-07-2017 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 SUPERFAMILY SSF103473 22 412 2.62E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 PRINTS PR01035 Tetracycline resistance protein signature 125 146 6.0E-12 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 PRINTS PR01035 Tetracycline resistance protein signature 358 381 6.0E-12 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 PRINTS PR01035 Tetracycline resistance protein signature 155 177 6.0E-12 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 PRINTS PR01035 Tetracycline resistance protein signature 36 52 6.0E-12 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS16050 bb4b52c72562b2f7da81477f4d2110c1 414 PRINTS PR01035 Tetracycline resistance protein signature 98 122 6.0E-12 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 Pfam PF00919 Uncharacterized protein family UPF0004 18 108 1.2E-20 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 18 447 2.0E-181 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 Gene3D G3DSA:2.40.50.140 390 452 6.7E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 SUPERFAMILY SSF102114 133 381 4.45E-54 T 06-07-2017 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 SMART SM00729 150 375 1.9E-56 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 154 174 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 Pfam PF04055 Radical SAM superfamily 156 332 7.8E-30 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 17 450 62.601 T 06-07-2017 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 18 448 3.2E-104 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAL12_RS26345 60698ae8f62e94798bc071b0bc8e7a7b 453 Gene3D G3DSA:3.80.30.20 148 387 6.8E-75 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAL12_RS01505 71de1cc402ddd7f7bc564675be9e26b2 317 SUPERFAMILY SSF53850 100 277 3.91E-10 T 06-07-2017 CAL12_RS01505 71de1cc402ddd7f7bc564675be9e26b2 317 PIRSF PIRSF017082 1 317 9.7E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01505 71de1cc402ddd7f7bc564675be9e26b2 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 313 2.6E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 SMART SM00852 174 312 2.0E-39 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Pfam PF00994 Probable molybdopterin binding domain 174 311 7.1E-28 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Gene3D G3DSA:2.40.340.10 327 397 4.7E-8 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 281 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Pfam PF03454 MoeA C-terminal region (domain IV) 327 395 2.8E-9 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 SUPERFAMILY SSF53218 171 317 2.49E-40 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 SUPERFAMILY SSF63867 323 400 3.27E-11 T 06-07-2017 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Gene3D G3DSA:3.90.105.10 125 156 9.5E-22 T 06-07-2017 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 SUPERFAMILY SSF63882 1 168 5.49E-51 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 161 1.3E-34 T 06-07-2017 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 308 2.5E-28 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Gene3D G3DSA:3.40.980.10 157 321 2.5E-60 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23930 75f2b6b408fc3b4383eda9d50137e32a 401 Gene3D G3DSA:2.170.190.11 45 124 1.1E-29 T 06-07-2017 CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 SMART SM00382 28 214 3.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 Gene3D G3DSA:3.40.50.300 2 239 8.5E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 SUPERFAMILY SSF52540 3 237 1.14E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 Pfam PF00005 ABC transporter 19 167 3.2E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 PIRSF PIRSF039085 1 242 2.5E-109 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS15465 529c1ba600ba0d4ef652b24f1cbcef58 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 SUPERFAMILY SSF46785 9 113 4.09E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 Pfam PF03466 LysR substrate binding domain 90 295 4.5E-48 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 Gene3D G3DSA:3.40.190.10 179 262 2.1E-22 T 06-07-2017 CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 Gene3D G3DSA:3.40.190.10 94 178 9.4E-28 T 06-07-2017 CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 Gene3D G3DSA:1.10.10.10 8 88 1.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 SUPERFAMILY SSF53850 91 297 4.65E-50 T 06-07-2017 CAL12_RS22870 49e69db6ce4816c07d9a37a3bdaa1003 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 6.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11625 944a95a0bec37d68523cee7040a2776e 458 Gene3D G3DSA:3.30.1330.120 263 399 3.0E-20 T 06-07-2017 CAL12_RS11625 944a95a0bec37d68523cee7040a2776e 458 Pfam PF03972 MmgE/PrpD family 12 431 1.3E-87 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS11625 944a95a0bec37d68523cee7040a2776e 458 SUPERFAMILY SSF103378 7 430 2.75E-82 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 SMART SM01092 181 270 2.2E-15 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 SUPERFAMILY SSF56176 1 175 1.42E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 Gene3D G3DSA:3.30.390.50 178 271 1.5E-15 T 06-07-2017 CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 3.6E-41 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 SUPERFAMILY SSF55447 179 270 8.11E-17 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 182 270 1.2E-7 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 Gene3D G3DSA:3.30.465.10 59 174 4.6E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS03310 951ba34bbeebab9ab886c339fa801a30 272 Gene3D G3DSA:3.30.43.10 1 54 3.2E-21 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00387 468 581 7.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00387 1216 1339 1.6E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF47384 1101 1172 1.75E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.40.50.2300 1357 1481 4.4E-30 T 06-07-2017 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.40.50.2300 1507 1618 5.8E-26 T 06-07-2017 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1323 1336 1.6E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1299 1317 1.6E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1286 1296 1.6E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1268 1282 1.6E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.30.450.40 769 950 3.1E-25 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.30.450.40 171 349 2.4E-8 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00091 977 1043 3.5E-4 T 06-07-2017 IPR000014 PAS domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.30.450.20 979 1113 9.1E-22 T 06-07-2017 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF08447 PAS fold 1001 1077 4.4E-12 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00388 1109 1175 0.0036 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00388 356 422 1.1E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF52172 1359 1482 6.26E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.30.565.10 1172 1340 2.2E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF55874 1165 1337 1.31E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF52172 1506 1620 2.85E-23 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF55781 193 347 9.81E-9 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:1.10.287.130 350 408 1.8E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:1.10.287.130 1114 1170 9.8E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF55874 411 579 1.44E-45 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.40.50.2300 639 766 1.9E-40 T 06-07-2017 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00065 793 948 2.4E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF52172 638 773 6.83E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1217 1338 6.6E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 474 579 8.9E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 981 1094 8.5E-11 T 06-07-2017 IPR000014 PAS domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF55781 775 968 4.36E-25 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF47384 341 423 1.94E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00448 1358 1471 1.1E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00448 1507 1617 9.8E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SMART SM00448 641 754 2.2E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF00072 Response regulator receiver domain 1360 1471 9.5E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF00072 Response regulator receiver domain 1509 1616 1.0E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF00072 Response regulator receiver domain 643 754 5.9E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF13185 GAF domain 792 939 1.4E-16 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF13185 GAF domain 189 335 1.5E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 422 2.1E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 SUPERFAMILY SSF55785 982 1090 6.28E-19 T 06-07-2017 IPR000014 PAS domain CAL12_RS07280 23c71b82339f511bb6cd0ac1bc5058b3 1621 Gene3D G3DSA:3.30.565.10 409 579 3.8E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SUPERFAMILY SSF55874 192 350 3.93E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Gene3D G3DSA:3.30.450.20 5 95 2.2E-12 T 06-07-2017 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SMART SM00388 124 189 4.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Gene3D G3DSA:1.10.287.130 117 181 2.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Gene3D G3DSA:3.30.565.10 188 351 6.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 351 4.7E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SMART SM00387 229 352 3.0E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 5.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 5.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 349 5.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 5.3E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Pfam PF13426 PAS domain 12 82 1.3E-6 T 06-07-2017 IPR000014 PAS domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 Pfam PF00512 His Kinase A (phospho-acceptor) domain 126 181 1.5E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SMART SM00091 1 66 4.5E-5 T 06-07-2017 IPR000014 PAS domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SUPERFAMILY SSF47384 113 184 6.87E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 114 3.2E-6 T 06-07-2017 IPR000014 PAS domain CAL12_RS15315 f1fc43f8794046be57d56a68529397dd 353 SUPERFAMILY SSF55785 5 83 1.59E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS14515 62ea647eff80368d4714977aee0745a6 437 Pfam PF07804 HipA-like C-terminal domain 287 404 7.6E-23 T 06-07-2017 IPR012893 HipA-like, C-terminal CAL12_RS14515 62ea647eff80368d4714977aee0745a6 437 Pfam PF07805 HipA-like N-terminal domain 176 245 6.1E-11 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 PIRSF PIRSF006485 3 471 1.7E-167 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Gene3D G3DSA:3.40.50.300 4 174 6.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Gene3D G3DSA:3.40.50.300 207 389 7.6E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 3.4E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 93 3.4E-8 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Pfam PF01926 50S ribosome-binding GTPase 7 123 3.6E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Pfam PF01926 50S ribosome-binding GTPase 210 327 1.9E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 SMART SM00382 3 143 0.69 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 SMART SM00382 206 349 0.32 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 463 5.5E-167 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Hamap MF_00195 GTPase Der [der]. 4 466 37.879 T 06-07-2017 IPR016484 GTP-binding protein EngA GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 207 374 3.5E-26 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 157 3.1E-16 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 SUPERFAMILY SSF52540 6 168 4.05E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 383 463 9.1E-25 T 06-07-2017 IPR032859 GTPase Der, C-terminal KH-domain-like CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 SUPERFAMILY SSF52540 140 169 4.09E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 SUPERFAMILY SSF52540 205 469 4.09E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09240 e4e380561e5cd6c0f3f1a052c9cc7f28 473 Gene3D G3DSA:3.30.300.20 390 465 4.4E-23 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS25110 2d90c463e4ba67a37af67f0e00e86be1 249 Gene3D G3DSA:2.60.440.10 171 248 1.6E-22 T 06-07-2017 IPR027462 Z ring-associated protein D, C-terminal domain CAL12_RS25110 2d90c463e4ba67a37af67f0e00e86be1 249 Gene3D G3DSA:1.10.3900.10 10 170 7.2E-55 T 06-07-2017 CAL12_RS25110 2d90c463e4ba67a37af67f0e00e86be1 249 Pfam PF07072 Protein of unknown function (DUF1342) 16 224 3.3E-70 T 06-07-2017 IPR009777 Cell division protein ZapD CAL12_RS25110 2d90c463e4ba67a37af67f0e00e86be1 249 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 248 31.126 T 06-07-2017 IPR009777 Cell division protein ZapD CAL12_RS25110 2d90c463e4ba67a37af67f0e00e86be1 249 SUPERFAMILY SSF160950 2 248 3.92E-81 T 06-07-2017 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 SMART SM01340 208 326 5.6E-54 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 SUPERFAMILY SSF55874 5 203 1.7E-50 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 208 325 2.9E-36 T 06-07-2017 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 SUPERFAMILY SSF54211 196 326 2.88E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 SMART SM00853 482 625 5.5E-55 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Gene3D G3DSA:3.30.565.10 6 209 3.4E-67 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 128 9.0E-12 T 06-07-2017 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Pfam PF08676 MutL C terminal dimerisation domain 478 625 2.0E-49 T 06-07-2017 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 06-07-2017 IPR014762 DNA mismatch repair, conserved site CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 SUPERFAMILY SSF118116 478 667 1.19E-58 T 06-07-2017 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 665 27.289 T 06-07-2017 IPR020667 DNA mismatch repair protein, MutL GO:0006298 CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 Gene3D G3DSA:3.30.230.10 210 325 3.0E-36 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS06400 fcbdec7242b8c113848dca821b19113e 669 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 7 306 6.0E-88 T 06-07-2017 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF55781 99 256 3.89E-15 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF47384 341 425 1.16E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF52172 814 939 5.12E-23 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF52172 693 809 2.99E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF00072 Response regulator receiver domain 816 924 9.8E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF00072 Response regulator receiver domain 961 1071 2.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF00072 Response regulator receiver domain 693 801 3.3E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF55874 413 579 1.11E-44 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 1.3E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:3.30.565.10 410 579 2.1E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00388 355 424 4.7E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:1.10.287.130 346 409 1.3E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF00512 His Kinase A (phospho-acceptor) domain 356 424 1.1E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:3.30.450.40 111 271 2.0E-13 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00065 124 266 1.3E-8 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00448 959 1073 1.3E-36 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00448 691 801 3.8E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00448 813 927 7.7E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SUPERFAMILY SSF52172 952 1077 4.98E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 472 579 7.3E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:3.40.50.2300 691 809 3.3E-25 T 06-07-2017 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 SMART SM00387 471 583 2.0E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:3.40.50.2300 953 1077 3.9E-41 T 06-07-2017 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Gene3D G3DSA:3.40.50.2300 813 934 4.8E-22 T 06-07-2017 CAL12_RS22760 0feca81f24bf86ccf723139c1d73990c 1079 Pfam PF13185 GAF domain 123 256 9.0E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS23910 5b8a718f6d8a079d172da48478fbd273 162 Pfam PF01967 MoaC family 19 154 1.9E-48 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAL12_RS23910 5b8a718f6d8a079d172da48478fbd273 162 Gene3D G3DSA:3.30.70.640 8 160 1.2E-61 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAL12_RS23910 5b8a718f6d8a079d172da48478fbd273 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 156 6.1E-55 T 06-07-2017 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CAL12_RS23910 5b8a718f6d8a079d172da48478fbd273 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 6 162 33.477 T 06-07-2017 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type Reactome: R-HSA-947581 CAL12_RS23910 5b8a718f6d8a079d172da48478fbd273 162 SUPERFAMILY SSF55040 15 159 1.07E-55 T 06-07-2017 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 Gene3D G3DSA:1.20.120.640 324 404 5.2E-20 T 06-07-2017 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 6.2E-28 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 6.2E-28 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 6.2E-28 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 6.2E-28 T 06-07-2017 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 Gene3D G3DSA:3.40.50.620 20 322 1.5E-89 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 Pfam PF09190 DALR domain 359 414 2.2E-15 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 481 8.7E-144 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 330 4.9E-110 T 06-07-2017 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 SUPERFAMILY SSF47323 333 480 9.42E-32 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 SUPERFAMILY SSF52374 2 331 4.22E-82 T 06-07-2017 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 SMART SM00840 359 414 2.3E-21 T 06-07-2017 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CAL12_RS07610 5e7e53ee8c5ce4bbe1d5bdf7d25c0cd5 482 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 481 36.429 T 06-07-2017 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 463 2.7E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 310 1.8E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 Gene3D G3DSA:3.30.565.10 313 469 4.5E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SUPERFAMILY SSF55874 300 467 3.93E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SUPERFAMILY SSF47384 228 310 4.12E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SUPERFAMILY SSF158472 192 241 1.23E-6 T 06-07-2017 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SMART SM00387 354 464 1.9E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 6 463 2.3E-144 T 06-07-2017 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 Gene3D G3DSA:1.10.287.130 235 307 4.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SMART SM00304 191 244 4.4E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 1.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 1.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 1.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 1.7E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 Pfam PF00672 HAMP domain 172 240 6.4E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS00220 304b27c9617b2db3a51f26cbc75927b2 485 SMART SM00388 245 311 1.3E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 Gene3D G3DSA:1.20.1250.20 269 424 7.7E-14 T 06-07-2017 CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 Gene3D G3DSA:1.20.1250.20 478 507 7.7E-14 T 06-07-2017 CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 Gene3D G3DSA:1.20.1250.20 14 200 1.1E-31 T 06-07-2017 CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 Pfam PF07690 Major Facilitator Superfamily 22 412 5.9E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 SUPERFAMILY SSF103473 16 206 6.8E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 SUPERFAMILY SSF103473 477 508 6.8E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06070 a7f97718435003d9b20319cef1343e56 512 SUPERFAMILY SSF103473 252 422 6.8E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 Gene3D G3DSA:3.40.50.300 13 222 3.6E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 Gene3D G3DSA:3.40.50.300 273 422 1.4E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 13 856 0.0 T 06-07-2017 IPR026362 DEXH box helicase, DNA ligase-associated CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 Pfam PF00271 Helicase conserved C-terminal domain 279 373 1.6E-11 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 SUPERFAMILY SSF52540 93 219 9.82E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 SUPERFAMILY SSF52540 250 385 9.82E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 SUPERFAMILY SSF52540 35 66 9.82E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 SMART SM00490 296 378 8.9E-16 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 Pfam PF00270 DEAD/DEAH box helicase 27 217 1.7E-23 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 Pfam PF08494 DEAD/H associated 640 827 1.7E-42 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 PIRSF PIRSF037307 2 863 1.3E-133 T 06-07-2017 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 CAL12_RS06920 9b660bdec835bce6803f70c8456decb3 868 SMART SM00487 21 245 5.1E-22 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 Gene3D G3DSA:3.90.76.10 65 150 1.6E-30 T 06-07-2017 CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 Gene3D G3DSA:3.10.105.10 294 489 1.9E-52 T 06-07-2017 CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 PIRSF PIRSF002741 6 521 6.6E-136 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 SUPERFAMILY SSF53850 29 514 1.25E-136 T 06-07-2017 CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 433 2.9E-89 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS03175 cc60d8391cd40d13c4489767c05a9a39 521 Gene3D G3DSA:3.40.190.10 151 293 6.3E-42 T 06-07-2017 CAL12_RS03770 949660d46070813a274785017d4bf405 225 Gene3D G3DSA:3.40.50.880 3 223 1.1E-70 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS03770 949660d46070813a274785017d4bf405 225 SUPERFAMILY SSF52317 5 221 1.99E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS03770 949660d46070813a274785017d4bf405 225 Pfam PF01965 DJ-1/PfpI family 29 210 1.4E-16 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 SUPERFAMILY SSF81296 415 533 1.96E-22 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 41 530 2.8E-172 T 06-07-2017 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 SUPERFAMILY SSF74650 41 413 5.65E-142 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 PIRSF PIRSF006281 1 534 1.5E-189 T 06-07-2017 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 Gene3D G3DSA:2.70.98.10 40 413 3.8E-150 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAL12_RS20890 e15c6103b474dcda02f291115393dedd 541 Gene3D G3DSA:2.60.40.10 416 540 2.3E-28 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS27580 0f177d9ff4f466460346c9a426aa27d4 254 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 57 212 4.0E-49 T 06-07-2017 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CAL12_RS27580 0f177d9ff4f466460346c9a426aa27d4 254 Gene3D G3DSA:2.60.120.330 110 214 6.9E-15 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAL12_RS27580 0f177d9ff4f466460346c9a426aa27d4 254 SUPERFAMILY SSF51197 69 247 7.96E-23 T 06-07-2017 CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 62 90 4.2E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 276 291 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 177 187 - T 06-07-2017 IPR019819 Carboxylesterase type B, conserved site CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 SUPERFAMILY SSF53474 93 571 4.65E-103 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 Gene3D G3DSA:3.40.50.1820 90 581 5.4E-128 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02840 511680b1e61551135d2de82870a80b0c 606 Pfam PF00135 Carboxylesterase family 92 575 7.0E-101 T 06-07-2017 IPR002018 Carboxylesterase, type B CAL12_RS22005 88cf1ed99115428b1653fff25cdc8b2f 124 Gene3D G3DSA:3.40.50.2300 3 116 3.6E-25 T 06-07-2017 CAL12_RS22005 88cf1ed99115428b1653fff25cdc8b2f 124 SUPERFAMILY SSF52172 6 116 1.32E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22005 88cf1ed99115428b1653fff25cdc8b2f 124 SMART SM00448 6 116 1.1E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22005 88cf1ed99115428b1653fff25cdc8b2f 124 Pfam PF00072 Response regulator receiver domain 8 112 7.2E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 Gene3D G3DSA:3.40.190.10 104 192 4.0E-17 T 06-07-2017 CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 SUPERFAMILY SSF53850 11 239 2.11E-48 T 06-07-2017 CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 15 239 1.5E-44 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 SMART SM00062 14 241 9.9E-41 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 Gene3D G3DSA:3.40.190.10 200 241 5.0E-33 T 06-07-2017 CAL12_RS14480 ac0a25c6e4d6281039e0e8f8b48d5619 250 Gene3D G3DSA:3.40.190.10 12 100 5.0E-33 T 06-07-2017 CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 SUPERFAMILY SSF55920 3 253 1.44E-88 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 252 6.3E-92 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 Pfam PF00557 Metallopeptidase family M24 12 245 6.9E-53 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 Hamap MF_01974 Methionine aminopeptidase [map]. 3 254 40.287 T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 Gene3D G3DSA:3.90.230.10 5 253 7.4E-89 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 171 189 - T 06-07-2017 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAL12_RS12110 8b2019eb0324f27912119866f4293333 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.1E-22 T 06-07-2017 IPR001714 Peptidase M24, methionine aminopeptidase CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 Pfam PF13525 Outer membrane lipoprotein 26 229 9.8E-58 T 06-07-2017 CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 237 36.822 T 06-07-2017 IPR017689 Outer membrane protein assembly factor BamD CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 SUPERFAMILY SSF48452 25 103 1.79E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 2 242 4.9E-81 T 06-07-2017 IPR017689 Outer membrane protein assembly factor BamD CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 Gene3D G3DSA:1.25.40.10 177 220 7.1E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS19185 e6c0717d87d22e2f16faec20a1f211a8 260 Gene3D G3DSA:1.25.40.10 26 104 7.1E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 Gene3D G3DSA:1.10.10.10 1 84 1.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 SUPERFAMILY SSF53850 90 300 1.81E-22 T 06-07-2017 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 Gene3D G3DSA:3.40.190.10 90 176 1.3E-9 T 06-07-2017 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 Pfam PF03466 LysR substrate binding domain 89 296 1.6E-19 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 SUPERFAMILY SSF46785 1 85 7.11E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14145 c4eb6115a61af25271aca79266f2432b 305 Gene3D G3DSA:3.40.190.10 231 264 7.3E-6 T 06-07-2017 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Pfam PF09285 Elongation factor P, C-terminal 128 183 7.0E-25 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 SUPERFAMILY SSF50104 1 63 1.75E-14 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 SMART SM00841 128 183 5.2E-29 T 06-07-2017 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Gene3D G3DSA:2.40.50.140 128 184 1.6E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 PIRSF PIRSF005901 1 185 8.0E-57 T 06-07-2017 IPR020599 Translation elongation factor P/YeiP CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 SMART SM01185 67 120 8.8E-22 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.1E-18 T 06-07-2017 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Gene3D G3DSA:2.40.50.140 65 126 6.7E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Hamap MF_00141 Elongation factor P [efp]. 1 184 47.162 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Gene3D G3DSA:2.30.30.30 1 62 1.3E-18 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.4E-17 T 06-07-2017 IPR013185 Translation elongation factor, KOW-like CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 8.0E-65 T 06-07-2017 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 06-07-2017 IPR013852 Translation elongation factor P/YeiP, conserved site CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 SUPERFAMILY SSF50249 128 184 3.08E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08145 b7705afc6f5f78e0bdf8491e2b7af91e 186 SUPERFAMILY SSF50249 65 126 2.12E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 5.7E-14 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 61 72 5.7E-14 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 35 43 5.7E-14 T 06-07-2017 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 7 310 1.5E-124 T 06-07-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 PIRSF PIRSF006431 1 314 7.5E-137 T 06-07-2017 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 Pfam PF00561 alpha/beta hydrolase fold 36 293 9.2E-29 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 Gene3D G3DSA:3.40.50.1820 7 297 9.4E-70 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02265 66815d005d88ed100872960d6783ac52 316 SUPERFAMILY SSF53474 4 304 6.49E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 PIRSF PIRSF019422 2 438 2.2E-121 T 06-07-2017 IPR026044 Membrane-bound lytic murein transglycosylase A CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 Pfam PF06725 3D domain 355 428 8.0E-23 T 06-07-2017 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 SUPERFAMILY SSF50685 57 432 9.42E-122 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 SMART SM00925 172 332 6.1E-88 T 06-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 Gene3D G3DSA:2.40.40.10 69 235 1.8E-27 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 Gene3D G3DSA:2.40.40.10 240 433 8.3E-56 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAL12_RS26085 2300f7a9a2fd9ae80487caa97017ccd9 439 Pfam PF03562 MltA specific insert domain 80 332 2.0E-78 T 06-07-2017 IPR005300 Lytic transglycosylase MltA GO:0004553 CAL12_RS06430 efcd46b8fb4dd4428f2600bd0b6a32d8 162 Pfam PF04073 Aminoacyl-tRNA editing domain 37 151 3.6E-26 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS06430 efcd46b8fb4dd4428f2600bd0b6a32d8 162 Gene3D G3DSA:3.90.960.10 4 159 4.0E-50 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS06430 efcd46b8fb4dd4428f2600bd0b6a32d8 162 SUPERFAMILY SSF55826 7 159 4.32E-43 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS06430 efcd46b8fb4dd4428f2600bd0b6a32d8 162 PIRSF PIRSF006181 5 162 1.8E-46 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAL12_RS06430 efcd46b8fb4dd4428f2600bd0b6a32d8 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 155 1.2E-47 T 06-07-2017 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 SMART SM00345 8 67 3.9E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 SUPERFAMILY SSF53383 102 460 2.85E-82 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 5.2E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 Gene3D G3DSA:3.40.640.10 137 352 6.2E-55 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 SUPERFAMILY SSF46785 3 69 1.52E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.6E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.6E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 Gene3D G3DSA:1.10.10.10 2 68 3.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21895 aab93c38e397d6d6dd30b586545c4b1f 462 Pfam PF00155 Aminotransferase class I and II 137 436 1.7E-21 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 Pfam PF07729 FCD domain 109 233 6.9E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 SUPERFAMILY SSF46785 23 89 1.09E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 Gene3D G3DSA:1.20.120.530 108 239 2.2E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 SMART SM00345 26 85 2.3E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 SMART SM00895 109 234 2.7E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 Gene3D G3DSA:1.10.10.10 23 89 9.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 SUPERFAMILY SSF48008 108 239 6.54E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21390 e1a4e0446206eb757a5f5ca9510670d4 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 85 7.8E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 SMART SM00644 64 206 1.7E-31 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 Gene3D G3DSA:3.40.80.10 68 225 4.2E-54 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 SUPERFAMILY SSF47090 230 298 1.96E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 Gene3D G3DSA:1.10.101.10 243 295 5.1E-5 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 74 207 1.4E-19 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 SUPERFAMILY SSF55846 66 224 1.37E-45 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS08325 de0e2a83fc05461181b5b2e914b777cc 312 Pfam PF01471 Putative peptidoglycan binding domain 242 295 1.2E-7 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 SUPERFAMILY SSF140490 355 453 2.48E-37 T 06-07-2017 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 SMART SM00928 358 403 1.9E-24 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 SUPERFAMILY SSF142984 270 353 2.22E-27 T 06-07-2017 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 SUPERFAMILY SSF142019 45 269 6.8E-84 T 06-07-2017 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 77 248 2.7E-46 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 44 444 2.8E-192 T 06-07-2017 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 371 382 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 362 443 1.9E-29 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19685 b44a00609932624ebc8a3869a9c98dfc 455 Pfam PF10531 SLBB domain 272 320 1.5E-13 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 SUPERFAMILY SSF46689 2 65 7.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 Gene3D G3DSA:1.10.357.10 2 189 6.2E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 49 4.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 5 18 4.8E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 SUPERFAMILY SSF48498 95 189 1.57E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS03235 d17fdbf665f36adda88b47f3dd10e337 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 5.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS27650 fa0d24b424f948e67b1d146acca4dc23 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 7.5E-70 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27650 fa0d24b424f948e67b1d146acca4dc23 205 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 7 205 31.56 T 06-07-2017 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27650 fa0d24b424f948e67b1d146acca4dc23 205 Gene3D G3DSA:3.40.1370.10 56 204 4.9E-55 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAL12_RS27650 fa0d24b424f948e67b1d146acca4dc23 205 SUPERFAMILY SSF52166 1 205 1.7E-69 T 06-07-2017 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CAL12_RS27650 fa0d24b424f948e67b1d146acca4dc23 205 Pfam PF00573 Ribosomal protein L4/L1 family 18 202 2.0E-62 T 06-07-2017 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CAL12_RS19045 1ccde1d226547d06d78bd0046d9a4111 379 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 13 374 4.1E-147 T 06-07-2017 IPR007434 Peptidogalycan biosysnthesis/recognition CAL12_RS19045 1ccde1d226547d06d78bd0046d9a4111 379 Gene3D G3DSA:3.40.630.30 176 326 1.5E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS19045 1ccde1d226547d06d78bd0046d9a4111 379 SUPERFAMILY SSF55729 176 350 3.81E-33 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 SMART SM00052 436 682 6.1E-120 T 06-07-2017 IPR001633 EAL domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 264 425 5.7E-45 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 SUPERFAMILY SSF141868 442 685 9.15E-90 T 06-07-2017 IPR001633 EAL domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Pfam PF00563 EAL domain 442 677 4.2E-73 T 06-07-2017 IPR001633 EAL domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 SMART SM00267 255 426 1.4E-63 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Gene3D G3DSA:3.20.20.450 440 687 2.6E-99 T 06-07-2017 IPR001633 EAL domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 110 1.1E-19 T 06-07-2017 IPR005330 MHYT domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Pfam PF03707 Bacterial signalling protein N terminal repeat 115 165 1.6E-15 T 06-07-2017 IPR005330 MHYT domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 248 2.2E-11 T 06-07-2017 IPR005330 MHYT domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Pfam PF00990 Diguanylate cyclase, GGDEF domain 266 422 5.2E-49 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 SUPERFAMILY SSF55073 271 427 4.12E-52 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS25335 1fbdde8b758ed7619e81fc4692047af1 696 Gene3D G3DSA:3.30.70.270 268 434 7.3E-61 T 06-07-2017 CAL12_RS03420 e6f776cd974d4655405748b9fbb377c1 335 PIRSF PIRSF017082 3 334 5.6E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03420 e6f776cd974d4655405748b9fbb377c1 335 SUPERFAMILY SSF53850 119 287 7.17E-16 T 06-07-2017 CAL12_RS03420 e6f776cd974d4655405748b9fbb377c1 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 4.9E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03420 e6f776cd974d4655405748b9fbb377c1 335 Gene3D G3DSA:3.40.190.10 136 234 7.5E-7 T 06-07-2017 CAL12_RS13060 501f193c7b41d7616bc8b9e16fcdf320 159 Gene3D G3DSA:3.40.50.2300 7 132 1.1E-34 T 06-07-2017 CAL12_RS13060 501f193c7b41d7616bc8b9e16fcdf320 159 SUPERFAMILY SSF52172 6 133 6.12E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS13060 501f193c7b41d7616bc8b9e16fcdf320 159 Pfam PF00072 Response regulator receiver domain 7 129 3.3E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13060 501f193c7b41d7616bc8b9e16fcdf320 159 SMART SM00448 5 129 6.9E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 127 2.9E-31 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 101 8.0E-14 T 06-07-2017 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 127 26.032 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 Gene3D G3DSA:1.20.5.710 2 52 1.8E-21 T 06-07-2017 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 SUPERFAMILY SSF54736 56 127 1.01E-24 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 5.0E-19 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 SUPERFAMILY SSF48300 4 63 4.05E-16 T 06-07-2017 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 Gene3D G3DSA:3.30.1390.10 55 127 3.4E-34 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAL12_RS27755 a07be5f0f3475cd6c2659eb227bd2065 127 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 127 3.4E-49 T 06-07-2017 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 Gene3D G3DSA:3.90.76.10 47 192 2.0E-35 T 06-07-2017 CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 422 1.7E-71 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 Gene3D G3DSA:3.10.105.10 301 484 6.9E-34 T 06-07-2017 CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 PIRSF PIRSF002741 1 516 5.7E-69 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 SUPERFAMILY SSF53850 34 514 2.4E-102 T 06-07-2017 CAL12_RS21475 9f546bb73696e043e6df12f179809eef 518 Gene3D G3DSA:3.40.190.10 193 300 1.8E-22 T 06-07-2017 CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 Gene3D G3DSA:1.20.1050.10 85 212 1.2E-28 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 Gene3D G3DSA:3.40.30.10 2 75 5.7E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 75 4.7E-12 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 SUPERFAMILY SSF52833 2 105 9.35E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 SUPERFAMILY SSF47616 80 213 6.25E-24 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS23835 4eb427ed83e143d22d075dc36feeac71 219 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 190 1.3E-9 T 06-07-2017 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 Gene3D G3DSA:1.10.10.10 7 84 8.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 SUPERFAMILY SSF53850 95 300 3.08E-23 T 06-07-2017 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 Pfam PF03466 LysR substrate binding domain 94 286 2.9E-18 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 Gene3D G3DSA:3.40.190.10 85 201 9.7E-8 T 06-07-2017 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 3.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 3.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 3.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 Gene3D G3DSA:3.40.190.10 202 251 2.2E-6 T 06-07-2017 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20105 5c0f3c4583e70c1631b10061b1c9e7bc 328 SUPERFAMILY SSF46785 8 90 1.11E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 786 0.0 T 06-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Gene3D G3DSA:3.30.470.20 192 346 1.9E-58 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 478 784 1.7E-56 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Gene3D G3DSA:3.20.20.60 479 786 5.3E-98 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 453 1.1E-25 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 347 3.6E-115 T 06-07-2017 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Gene3D G3DSA:3.50.30.10 371 472 5.5E-36 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 PIRSF PIRSF000854 1 787 0.0 T 06-07-2017 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 SUPERFAMILY SSF52009 345 465 9.29E-34 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 Gene3D G3DSA:3.30.1490.20 2 190 1.4E-66 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 SUPERFAMILY SSF56059 1 382 3.04E-108 T 06-07-2017 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 SUPERFAMILY SSF51621 464 786 4.71E-91 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS12200 348dab849168067e57c65c1462a5020a 787 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 692 710 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CAL12_RS02270 ff66ca703dc5cce4e4eeff826fd209e2 263 Pfam PF02390 Putative methyltransferase 90 257 2.6E-54 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAL12_RS02270 ff66ca703dc5cce4e4eeff826fd209e2 263 SUPERFAMILY SSF53335 44 261 3.44E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02270 ff66ca703dc5cce4e4eeff826fd209e2 263 Gene3D G3DSA:3.40.50.150 67 229 1.3E-16 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02270 ff66ca703dc5cce4e4eeff826fd209e2 263 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 50 262 30.623 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAL12_RS02270 ff66ca703dc5cce4e4eeff826fd209e2 263 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 83 261 7.7E-53 T 06-07-2017 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CAL12_RS27700 b9cce8c9a74cef67ab30eb3235a0f8cd 231 Gene3D G3DSA:1.10.3720.10 15 214 9.4E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27700 b9cce8c9a74cef67ab30eb3235a0f8cd 231 SUPERFAMILY SSF161098 15 206 9.55E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27700 b9cce8c9a74cef67ab30eb3235a0f8cd 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 112 1.6E-21 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS27700 b9cce8c9a74cef67ab30eb3235a0f8cd 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 202 7.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10815 cf6dac5a351bf820a784626d122b4448 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 3.5E-29 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS10815 cf6dac5a351bf820a784626d122b4448 224 Gene3D G3DSA:1.10.3720.10 10 210 2.6E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10815 cf6dac5a351bf820a784626d122b4448 224 SUPERFAMILY SSF161098 11 202 1.44E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10815 cf6dac5a351bf820a784626d122b4448 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 213 4.7E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14590 8a377b537fef47fc7603351f3f06e678 373 SUPERFAMILY SSF53850 149 336 4.44E-12 T 06-07-2017 CAL12_RS14590 8a377b537fef47fc7603351f3f06e678 373 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 97 352 9.0E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14590 8a377b537fef47fc7603351f3f06e678 373 PIRSF PIRSF017082 44 373 4.5E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 125 140 - T 06-07-2017 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 8.3E-47 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 308 2.0E-119 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 199 308 1.1E-26 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 309 47.677 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 SUPERFAMILY SSF53271 65 300 1.28E-64 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 SMART SM01400 1 117 9.9E-71 T 06-07-2017 CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 Gene3D G3DSA:3.40.50.2020 156 282 6.9E-54 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS02800 19584c959fb31f36d57284d38107b2f7 310 Gene3D G3DSA:3.40.50.2020 1 155 3.9E-70 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 134 188 1.5E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 298 372 1.5E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 29 145 4.5E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 375 472 2.8E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 632 780 2.8E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 SMART SM01008 28 145 5.3E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 165 717 2.7E-166 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 189 295 9.4E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 SUPERFAMILY SSF56003 137 780 1.16E-182 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.90.1170.50 12 133 8.2E-34 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 SUPERFAMILY SSF54665 12 167 3.53E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS15650 4daf7ced9662fe4fb000c3a1ca9f3566 785 Gene3D G3DSA:3.30.365.10 473 630 1.8E-41 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS18150 a864d274a7957c643a4c709bf68f4829 323 SUPERFAMILY SSF53850 115 283 8.36E-11 T 06-07-2017 CAL12_RS18150 a864d274a7957c643a4c709bf68f4829 323 PIRSF PIRSF017082 1 323 2.9E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18150 a864d274a7957c643a4c709bf68f4829 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 317 6.2E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 Gene3D G3DSA:3.40.50.300 4 242 2.3E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 SUPERFAMILY SSF52540 5 240 2.66E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 Pfam PF00005 ABC transporter 21 169 1.5E-38 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 PIRSF PIRSF039085 2 246 1.7E-107 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS25240 77145176790365b5961732c2e46af8c9 246 SMART SM00382 30 218 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Pfam PF06827 Zinc finger found in FPG and IleRS 246 273 1.8E-9 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 SUPERFAMILY SSF57716 221 273 2.38E-14 T 06-07-2017 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 SMART SM00898 2 115 9.5E-47 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Gene3D G3DSA:1.10.8.50 134 274 9.9E-45 T 06-07-2017 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 1.2E-80 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 39.857 T 06-07-2017 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 SUPERFAMILY SSF46946 134 225 1.21E-25 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.8E-29 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Gene3D G3DSA:3.20.190.10 2 133 9.1E-35 T 06-07-2017 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 1.4E-20 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 SUPERFAMILY SSF81624 2 142 1.57E-37 T 06-07-2017 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 SMART SM01232 133 225 1.1E-40 T 06-07-2017 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CAL12_RS02775 3d85f3969c528d53889dfaf493ad78bd 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 06-07-2017 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CAL12_RS05990 2bd0fdd95ce545d48ddfee564870023a 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 1.2E-103 T 06-07-2017 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CAL12_RS05990 2bd0fdd95ce545d48ddfee564870023a 232 SUPERFAMILY SSF52540 2 219 3.17E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05990 2bd0fdd95ce545d48ddfee564870023a 232 SMART SM00382 26 211 4.6E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05990 2bd0fdd95ce545d48ddfee564870023a 232 Gene3D G3DSA:3.40.50.300 1 220 2.6E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05990 2bd0fdd95ce545d48ddfee564870023a 232 Pfam PF00005 ABC transporter 17 161 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 SUPERFAMILY SSF51735 1 112 4.68E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 SUPERFAMILY SSF48179 199 332 1.39E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 333 1.8E-52 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 199 330 1.2E-26 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 171 1.0E-19 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 Gene3D G3DSA:3.40.50.720 1 195 4.3E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04655 8ede3acb6eb3d249aaff7c7cb6efe098 340 Gene3D G3DSA:1.10.1040.10 200 334 5.0E-26 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS15750 56d0569319e6797ca17e31704be83056 218 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 43 202 1.4E-27 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS15750 56d0569319e6797ca17e31704be83056 218 Gene3D G3DSA:3.40.50.1110 39 217 1.1E-52 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS15750 56d0569319e6797ca17e31704be83056 218 SUPERFAMILY SSF52266 37 217 9.47E-49 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 Pfam PF12833 Helix-turn-helix domain 254 332 2.0E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 SUPERFAMILY SSF46689 284 333 7.62E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 Gene3D G3DSA:1.10.10.60 238 284 5.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 SMART SM00342 248 331 4.8E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 Gene3D G3DSA:3.40.50.880 21 237 1.9E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 Gene3D G3DSA:1.10.10.60 285 333 1.2E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 Pfam PF01965 DJ-1/PfpI family 56 190 9.1E-13 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 SUPERFAMILY SSF52317 21 211 4.23E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06150 03f65d43e1c52423a0afccf74fa6ce0b 338 SUPERFAMILY SSF46689 231 281 2.51E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12185 6c49dbf54714cba8b1403b03e75e7db9 202 SUPERFAMILY SSF53098 15 199 6.98E-63 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS12185 6c49dbf54714cba8b1403b03e75e7db9 202 Gene3D G3DSA:3.30.420.10 16 155 6.7E-41 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS12185 6c49dbf54714cba8b1403b03e75e7db9 202 Hamap MF_00052_B Ribonuclease HII [rnhB]. 16 195 35.589 T 06-07-2017 IPR022898 Ribonuclease HII GO:0004523 CAL12_RS12185 6c49dbf54714cba8b1403b03e75e7db9 202 Pfam PF01351 Ribonuclease HII 19 193 1.0E-34 T 06-07-2017 IPR024567 Ribonuclease HII/HIII domain CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 SUPERFAMILY SSF53474 15 347 1.53E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 323 534 2.5E-25 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Gene3D G3DSA:1.10.3020.10 151 229 5.4E-7 T 06-07-2017 CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 21 287 5.2E-63 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 SMART SM00939 311 550 8.1E-59 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Gene3D G3DSA:2.60.120.260 341 552 1.7E-46 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 SUPERFAMILY SSF49785 341 551 1.42E-42 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Gene3D G3DSA:3.40.50.1820 13 150 1.8E-77 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 Gene3D G3DSA:3.40.50.1820 230 340 1.8E-77 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24480 e5c794d0a6974f6f9c88d3e717451ecb 563 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 17 552 7.2E-128 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 SMART SM00347 39 137 4.3E-25 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 Pfam PF01047 MarR family 46 104 4.3E-16 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 Gene3D G3DSA:1.10.10.10 9 153 4.0E-43 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 SUPERFAMILY SSF46785 15 152 5.62E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08750 6170aee7b3b58e763f0b30c049830db7 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 1.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 SUPERFAMILY SSF56524 86 326 1.96E-70 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 292 406 5.8E-15 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 8 419 6.6E-183 T 06-07-2017 IPR030835 Sulfite dehydrogenase SoxC CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 Gene3D G3DSA:3.90.420.10 64 296 4.2E-66 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 Gene3D G3DSA:2.60.40.650 297 411 3.1E-27 T 06-07-2017 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 Pfam PF00174 Oxidoreductase molybdopterin binding domain 112 269 7.9E-48 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 SUPERFAMILY SSF81296 295 410 4.41E-31 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 220 236 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 237 250 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 253 266 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 56 70 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 318 332 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS07325 ae4c5f743d0b8adf70fcfc922e7f3a89 421 PRINTS PR00407 Eukaryotic molybdopterin domain signature 375 387 1.1E-15 T 06-07-2017 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 Gene3D G3DSA:3.30.1330.60 1057 1099 8.8E-10 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 Gene3D G3DSA:3.30.1330.60 1181 1213 8.8E-10 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 SUPERFAMILY SSF103088 1055 1101 5.1E-5 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 Pfam PF05359 Domain of Unknown Function (DUF748) 157 310 5.1E-22 T 06-07-2017 IPR008023 Protein of unknown function DUF748 CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 Pfam PF05359 Domain of Unknown Function (DUF748) 844 989 9.5E-36 T 06-07-2017 IPR008023 Protein of unknown function DUF748 CAL12_RS23905 b2cb2ef5b510008670832cd31e0295f8 1237 Pfam PF05359 Domain of Unknown Function (DUF748) 585 738 7.0E-23 T 06-07-2017 IPR008023 Protein of unknown function DUF748 CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 SUPERFAMILY SSF52972 13 203 3.53E-58 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 PIRSF PIRSF006305 6 208 1.7E-54 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 Hamap MF_00528 Septum formation protein Maf [maf]. 14 208 29.841 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 Gene3D G3DSA:3.90.950.10 13 206 2.3E-64 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 TIGRFAM TIGR00172 maf: septum formation protein Maf 13 202 5.0E-44 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS17895 7705c84e020fb0ed1e35ed66f40de1f7 209 Pfam PF02545 Maf-like protein 14 203 1.3E-53 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Gene3D G3DSA:3.30.450.20 8 118 3.2E-12 T 06-07-2017 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SUPERFAMILY SSF55785 118 247 4.03E-31 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 14 127 2.2E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 129 255 1.5E-36 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SUPERFAMILY SSF55874 337 487 4.58E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Pfam PF00989 PAS fold 134 246 2.1E-16 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00086 80 121 0.48 T 06-07-2017 IPR001610 PAC motif CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00086 209 249 6.7 T 06-07-2017 IPR001610 PAC motif CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00388 269 337 1.4E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00091 133 199 1.6E-14 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00091 9 76 8.9 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 484 8.5E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SUPERFAMILY SSF55785 20 129 4.19E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SMART SM00387 376 487 1.5E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Pfam PF08448 PAS fold 18 123 3.8E-7 T 06-07-2017 IPR013656 PAS fold-4 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Gene3D G3DSA:3.30.565.10 339 489 9.6E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Gene3D G3DSA:3.30.450.20 120 247 1.3E-33 T 06-07-2017 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 335 8.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 2.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 2.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 484 2.9E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 Gene3D G3DSA:1.10.287.130 262 333 6.3E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14375 2b5dcc86b09665ca46e9c2a56438d2d3 499 SUPERFAMILY SSF47384 256 335 3.92E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 SUPERFAMILY SSF53850 1 267 1.9E-53 T 06-07-2017 CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 SMART SM00062 45 268 2.5E-36 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 268 6.9E-40 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 Gene3D G3DSA:3.40.190.10 124 204 1.8E-4 T 06-07-2017 CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 Gene3D G3DSA:3.40.190.10 228 267 6.5E-31 T 06-07-2017 CAL12_RS04895 7b6b30ef804a93f16f996ef94684a2b9 268 Gene3D G3DSA:3.40.190.10 42 123 6.5E-31 T 06-07-2017 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 PIRSF PIRSF000124 1 418 1.7E-47 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 PIRSF PIRSF500136 1 419 1.7E-135 T 06-07-2017 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 307 406 5.8E-18 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 401 1.2E-109 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 SMART SM00984 307 407 7.2E-18 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 Gene3D G3DSA:3.40.50.720 222 411 2.3E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 SUPERFAMILY SSF48179 191 281 1.0E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 SUPERFAMILY SSF52413 291 406 1.83E-19 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 170 3.4E-31 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 SUPERFAMILY SSF51735 1 182 2.66E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 280 1.7E-23 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS21960 a127e100045914bf1caa1ae457189eec 419 Gene3D G3DSA:3.40.50.720 1 212 1.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 SUPERFAMILY SSF51126 833 1048 8.16E-41 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Gene3D G3DSA:2.160.20.20 822 901 3.9E-12 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Gene3D G3DSA:2.160.20.20 906 1048 1.7E-23 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Gene3D G3DSA:2.160.20.20 96 469 3.1E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Gene3D G3DSA:2.160.20.20 474 821 1.4E-11 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 SUPERFAMILY SSF51126 626 849 4.08E-13 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Gene3D G3DSA:2.40.128.130 1057 1395 3.2E-58 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 SMART SM00869 1119 1382 7.2E-34 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 SUPERFAMILY SSF103515 1078 1395 3.01E-37 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Pfam PF03797 Autotransporter beta-domain 1120 1376 5.4E-41 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 928 1395 5.8E-67 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Pfam PF12951 Passenger-associated-transport-repeat 862 891 1.3E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Pfam PF12951 Passenger-associated-transport-repeat 794 823 3.0E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 Pfam PF12951 Passenger-associated-transport-repeat 507 537 0.0012 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 506 538 7.1E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 861 892 2.3E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 793 824 7.4E-12 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05335 f47fe67c9c911fd202285a21bbe7e013 1395 SUPERFAMILY SSF51126 484 626 2.29E-9 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 SUPERFAMILY SSF46785 27 97 1.32E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 SMART SM00345 35 93 1.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 Gene3D G3DSA:1.20.120.530 97 241 9.2E-10 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 Gene3D G3DSA:1.10.10.10 26 93 1.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 93 3.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 SMART SM00895 103 233 2.9E-4 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 SUPERFAMILY SSF48008 100 240 4.45E-9 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS07645 c4f47487a955e4fdb1f72a266a478b8f 245 Pfam PF07729 FCD domain 103 231 8.3E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS09000 7f2fb6e57c2882f37c9da6450f339613 197 Gene3D G3DSA:3.90.79.10 15 183 6.6E-54 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS09000 7f2fb6e57c2882f37c9da6450f339613 197 Pfam PF00293 NUDIX domain 51 160 8.7E-16 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS09000 7f2fb6e57c2882f37c9da6450f339613 197 SUPERFAMILY SSF55811 17 183 7.31E-48 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 Gene3D G3DSA:3.90.650.10 143 318 4.0E-45 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 25 136 8.0E-26 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 149 300 4.3E-11 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 PIRSF PIRSF005303 2 318 7.3E-78 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 315 28.314 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 SUPERFAMILY SSF56042 141 304 3.74E-35 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 SUPERFAMILY SSF55326 4 136 1.02E-35 T 06-07-2017 CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 Gene3D G3DSA:3.30.1330.10 3 139 1.6E-44 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS02975 3b61aca7c4b6873017ab8a02e8c3f363 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 318 1.9E-95 T 06-07-2017 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 Pfam PF08281 Sigma-70, region 4 134 182 1.2E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 184 6.9E-34 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 SUPERFAMILY SSF88946 3 104 2.67E-32 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 191 1.2E-93 T 06-07-2017 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 Gene3D G3DSA:1.10.1740.10 3 112 5.7E-38 T 06-07-2017 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 Gene3D G3DSA:1.10.10.10 125 189 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 Pfam PF04542 Sigma-70 region 2 25 92 7.7E-19 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08385 0ae491af4448a53cbb9509f772ef856c 199 SUPERFAMILY SSF88659 125 187 2.01E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Gene3D G3DSA:3.30.300.30 413 511 1.3E-26 T 06-07-2017 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 SUPERFAMILY SSF56801 13 512 3.14E-137 T 06-07-2017 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Gene3D G3DSA:2.30.38.10 342 412 1.8E-16 T 06-07-2017 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Gene3D G3DSA:3.40.50.980 187 341 4.3E-43 T 06-07-2017 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 502 1.1E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Pfam PF00501 AMP-binding enzyme 14 418 2.9E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Gene3D G3DSA:3.40.50.980 16 114 4.2E-34 T 06-07-2017 CAL12_RS12780 dd131423d5f2f2360397bc16d54e8ca5 515 Gene3D G3DSA:3.40.50.980 163 186 4.2E-34 T 06-07-2017 CAL12_RS08085 31df858f33dd2a5e6d46cd08c3e4bc11 310 Gene3D G3DSA:3.20.20.410 11 302 1.1E-85 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08085 31df858f33dd2a5e6d46cd08c3e4bc11 310 SUPERFAMILY SSF117396 15 143 1.44E-77 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08085 31df858f33dd2a5e6d46cd08c3e4bc11 310 SUPERFAMILY SSF117396 171 301 1.44E-77 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08085 31df858f33dd2a5e6d46cd08c3e4bc11 310 Pfam PF01904 Protein of unknown function DUF72 32 298 9.5E-67 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS09375 029263069382c5fbfbe8816a64e1d291 91 Pfam PF07369 Protein of unknown function (DUF1488) 10 71 9.4E-5 T 06-07-2017 IPR009962 Protein of unknown function DUF1488 CAL12_RS10875 9a31b8cddb5c6ad50506a3c4632b4ebd 173 Pfam PF06172 Cupin superfamily (DUF985) 10 145 1.0E-46 T 06-07-2017 IPR009327 Cupin domain of unknown function DUF985 CAL12_RS10875 9a31b8cddb5c6ad50506a3c4632b4ebd 173 Gene3D G3DSA:2.60.120.10 4 165 3.1E-61 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS10875 9a31b8cddb5c6ad50506a3c4632b4ebd 173 SUPERFAMILY SSF51182 6 165 4.45E-58 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 Pfam PF02355 Protein export membrane protein 435 597 7.8E-20 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 616 48.099 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 Gene3D G3DSA:1.20.1640.10 447 612 3.7E-24 T 06-07-2017 CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 Pfam PF07549 SecD/SecF GG Motif 131 152 2.1E-4 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 135 601 9.5E-144 T 06-07-2017 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 361 595 8.8E-74 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 SUPERFAMILY SSF82866 412 611 9.55E-40 T 06-07-2017 CAL12_RS04920 ab9967e3bd2bf4eb93f172f85d75b39d 631 Pfam PF13721 SecD export protein N-terminal TM region 1 112 1.3E-35 T 06-07-2017 IPR027398 SecD export protein N-terminal TM domain CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 Gene3D G3DSA:1.10.260.40 36 136 1.4E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 Gene3D G3DSA:2.60.120.10 137 213 1.2E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 SMART SM00530 39 94 7.2E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 SUPERFAMILY SSF47413 34 98 7.32E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 Pfam PF01381 Helix-turn-helix 40 93 1.2E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 Pfam PF07883 Cupin domain 143 211 2.3E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS01330 6d4e3e6ead08c3e70d3e3e0d2f307192 239 SUPERFAMILY SSF51182 79 214 2.56E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 192 2.4E-5 T 06-07-2017 CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 SUPERFAMILY SSF51735 2 250 7.35E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 248 1.2E-53 T 06-07-2017 CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 5.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 5.2E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 Gene3D G3DSA:3.40.50.720 2 250 5.4E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10670 521591e6bf59de6147fe5f66900114b2 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.2E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 Gene3D G3DSA:1.10.45.10 429 468 2.5E-14 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 Gene3D G3DSA:3.30.465.10 94 215 1.6E-38 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 Gene3D G3DSA:3.30.43.10 3 93 9.9E-25 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 SUPERFAMILY SSF56176 3 215 4.36E-77 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 Pfam PF01565 FAD binding domain 38 175 3.4E-37 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 SUPERFAMILY SSF55103 218 469 1.41E-57 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS02715 c60e06a86d0c483035970e86626a0eb6 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 468 2.6E-55 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 304 1.0E-38 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Gene3D G3DSA:3.40.50.720 13 138 1.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 SUPERFAMILY SSF51735 10 146 5.76E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 SUPERFAMILY SSF52210 314 463 2.93E-20 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 SUPERFAMILY SSF52210 163 305 3.66E-29 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 SUPERFAMILY SSF56059 499 710 9.86E-33 T 06-07-2017 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Gene3D G3DSA:3.40.50.261 139 303 1.8E-18 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Pfam PF13549 ATP-grasp domain 496 710 1.1E-53 T 06-07-2017 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Pfam PF13380 CoA binding domain 21 139 5.4E-19 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 Gene3D G3DSA:3.30.470.20 503 608 1.5E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS16600 4412e5cc7a8e56b31b62e4501a127b7f 713 SMART SM00881 16 111 1.1E-28 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Gene3D G3DSA:2.30.38.10 402 469 4.9E-13 T 06-07-2017 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 ProSitePatterns PS00455 Putative AMP-binding domain signature. 238 249 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Gene3D G3DSA:3.30.300.30 474 576 2.2E-30 T 06-07-2017 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 SUPERFAMILY SSF56801 54 578 6.8E-133 T 06-07-2017 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Pfam PF13193 AMP-binding enzyme C-terminal domain 488 566 2.3E-23 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Gene3D G3DSA:3.40.50.980 70 243 4.7E-34 T 06-07-2017 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Pfam PF00501 AMP-binding enzyme 77 479 8.4E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS24990 d6629da066c0cec98f17a2a1106a1d35 579 Gene3D G3DSA:3.40.50.980 244 401 1.4E-32 T 06-07-2017 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 Pfam PF01380 SIS domain 46 177 2.1E-29 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 319 3.1E-102 T 06-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 SUPERFAMILY SSF53697 15 327 4.45E-67 T 06-07-2017 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 Gene3D G3DSA:3.10.580.10 200 325 4.5E-36 T 06-07-2017 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 Gene3D G3DSA:3.40.50.10490 16 199 2.3E-50 T 06-07-2017 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 PIRSF PIRSF004692 2 329 4.5E-128 T 06-07-2017 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 SMART SM00116 280 328 20.0 T 06-07-2017 IPR000644 CBS domain CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 SMART SM00116 215 263 0.0071 T 06-07-2017 IPR000644 CBS domain CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 Pfam PF00571 CBS domain 277 326 8.4E-6 T 06-07-2017 IPR000644 CBS domain CAL12_RS01740 de56697d9f2b7e6af157df4d0e9b8f09 329 Pfam PF00571 CBS domain 206 262 1.6E-6 T 06-07-2017 IPR000644 CBS domain CAL12_RS14270 ad1cbed6024e514f914dabc50260c9dc 451 SUPERFAMILY SSF103378 3 443 8.89E-89 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS14270 ad1cbed6024e514f914dabc50260c9dc 451 Gene3D G3DSA:3.30.1330.120 264 385 1.6E-19 T 06-07-2017 CAL12_RS14270 ad1cbed6024e514f914dabc50260c9dc 451 Pfam PF03972 MmgE/PrpD family 7 436 6.3E-88 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS15160 b35420cb98617610a67fbee3757a9a6d 239 Pfam PF03737 Demethylmenaquinone methyltransferase 17 182 7.3E-32 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS15160 b35420cb98617610a67fbee3757a9a6d 239 Gene3D G3DSA:3.50.30.40 14 190 1.2E-43 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS15160 b35420cb98617610a67fbee3757a9a6d 239 SUPERFAMILY SSF89562 14 193 1.23E-42 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS02340 d36e364b0139bc8a1da03016d7f8cae5 409 Pfam PF07805 HipA-like N-terminal domain 174 244 1.9E-8 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAL12_RS02340 d36e364b0139bc8a1da03016d7f8cae5 409 Pfam PF13657 HipA N-terminal domain 18 92 3.2E-6 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS02340 d36e364b0139bc8a1da03016d7f8cae5 409 Pfam PF07804 HipA-like C-terminal domain 250 383 5.1E-27 T 06-07-2017 IPR012893 HipA-like, C-terminal CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1087 1344 4.9E-94 T 06-07-2017 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1345 20.36 T 06-07-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF55326 643 839 9.16E-62 T 06-07-2017 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Pfam PF02769 AIR synthase related protein, C-terminal domain 847 1013 3.0E-13 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Pfam PF02769 AIR synthase related protein, C-terminal domain 444 600 7.2E-27 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF56042 441 679 2.69E-47 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SMART SM01211 1087 1344 1.1E-125 T 06-07-2017 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF109736 167 230 3.92E-21 T 06-07-2017 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF52317 1083 1344 1.03E-83 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF82697 5 160 1.46E-41 T 06-07-2017 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 9 1344 0.0 T 06-07-2017 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Gene3D G3DSA:3.40.50.880 1088 1311 2.7E-9 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Gene3D G3DSA:3.30.1330.10 221 433 3.5E-38 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 Gene3D G3DSA:3.30.1330.10 669 833 4.8E-14 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF56042 848 1081 2.39E-49 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS17065 a675423b96794ac2d3a76f096691f302 1345 SUPERFAMILY SSF55326 231 434 2.34E-55 T 06-07-2017 CAL12_RS21415 5aaa26abd5ac2280b52ab37670697379 231 Pfam PF13531 Bacterial extracellular solute-binding protein 3 229 7.1E-27 T 06-07-2017 CAL12_RS21415 5aaa26abd5ac2280b52ab37670697379 231 Gene3D G3DSA:3.40.190.10 2 134 1.0E-11 T 06-07-2017 CAL12_RS21415 5aaa26abd5ac2280b52ab37670697379 231 SUPERFAMILY SSF53850 2 230 1.3E-27 T 06-07-2017 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.3E-43 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 Gene3D G3DSA:2.40.50.140 1 123 3.0E-65 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.1E-61 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 PIRSF PIRSF002133 1 124 1.8E-54 T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 06-07-2017 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.0E-69 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 SUPERFAMILY SSF50249 2 124 1.63E-52 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27680 b9dbd71027973b3e6f9b5ee83d62a697 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.404 T 06-07-2017 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08790 4c96510b7d639b795af272de1292feaa 391 Gene3D G3DSA:1.20.1250.20 7 175 6.0E-25 T 06-07-2017 CAL12_RS08790 4c96510b7d639b795af272de1292feaa 391 Pfam PF07690 Major Facilitator Superfamily 5 344 4.8E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS08790 4c96510b7d639b795af272de1292feaa 391 SUPERFAMILY SSF103473 3 372 5.62E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS08790 4c96510b7d639b795af272de1292feaa 391 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 373 8.2E-90 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAL12_RS08790 4c96510b7d639b795af272de1292feaa 391 Gene3D G3DSA:1.20.1250.20 196 373 8.0E-7 T 06-07-2017 CAL12_RS12240 e9db13ec95a6dae6b9114899fa650c47 112 Pfam PF03658 RnfH family Ubiquitin 8 89 2.1E-29 T 06-07-2017 IPR005346 RnfH protein CAL12_RS12240 e9db13ec95a6dae6b9114899fa650c47 112 SUPERFAMILY SSF54285 6 81 5.23E-23 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAL12_RS12240 e9db13ec95a6dae6b9114899fa650c47 112 Gene3D G3DSA:3.10.20.280 3 91 1.5E-31 T 06-07-2017 IPR005346 RnfH protein CAL12_RS12240 e9db13ec95a6dae6b9114899fa650c47 112 Hamap MF_00460 Protein RnfH [rnfH]. 7 98 21.815 T 06-07-2017 IPR005346 RnfH protein CAL12_RS21285 f4cfc77207ecdf77a090fea128a28cc3 213 Pfam PF00510 Cytochrome c oxidase subunit III 30 210 8.0E-15 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21285 f4cfc77207ecdf77a090fea128a28cc3 213 SUPERFAMILY SSF81452 28 210 2.35E-58 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21285 f4cfc77207ecdf77a090fea128a28cc3 213 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 33 212 5.0E-83 T 06-07-2017 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 CAL12_RS21285 f4cfc77207ecdf77a090fea128a28cc3 213 Gene3D G3DSA:1.20.120.80 30 210 8.5E-52 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 100 117 - T 06-07-2017 IPR018046 Pili assembly chaperone, conserved site CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 PRINTS PR00969 Pili chaperone signature 24 33 1.3E-30 T 06-07-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 PRINTS PR00969 Pili chaperone signature 167 182 1.3E-30 T 06-07-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 PRINTS PR00969 Pili chaperone signature 73 94 1.3E-30 T 06-07-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 PRINTS PR00969 Pili chaperone signature 101 118 1.3E-30 T 06-07-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 PRINTS PR00969 Pili chaperone signature 128 143 1.3E-30 T 06-07-2017 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 Gene3D G3DSA:2.60.40.1070 148 239 6.1E-16 T 06-07-2017 IPR016148 Pili assembly chaperone, C-terminal CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 146 6.3E-46 T 06-07-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 SUPERFAMILY SSF49584 147 240 4.06E-13 T 06-07-2017 IPR016148 Pili assembly chaperone, C-terminal CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 Gene3D G3DSA:2.60.40.360 23 147 1.0E-47 T 06-07-2017 IPR008962 PapD-like CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 173 236 1.5E-9 T 06-07-2017 IPR016148 Pili assembly chaperone, C-terminal CAL12_RS04575 196075c13b6a41f8c7484042123bf9b5 243 SUPERFAMILY SSF49354 18 146 1.13E-45 T 06-07-2017 IPR008962 PapD-like CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 Gene3D G3DSA:3.30.450.40 76 248 4.1E-61 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 Pfam PF01614 Bacterial transcriptional regulator 121 243 3.2E-31 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 Gene3D G3DSA:1.10.10.10 4 72 5.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 SUPERFAMILY SSF46785 3 76 4.5E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 SUPERFAMILY SSF55781 68 248 4.97E-55 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 SMART SM00346 2 93 6.2E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS12760 4b8fd0c5afd85f358958973b48815053 251 Pfam PF09339 IclR helix-turn-helix domain 5 55 2.0E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 Pfam PF01799 [2Fe-2S] binding domain 77 150 3.1E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 Gene3D G3DSA:3.10.20.30 4 78 6.7E-31 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 SUPERFAMILY SSF47741 89 160 4.58E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 Gene3D G3DSA:1.10.150.120 79 161 5.3E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 SUPERFAMILY SSF54292 6 92 4.19E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS20665 77a1fb97f4af330a8501d92ff06ea792 166 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 67 7.5E-11 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Pfam PF12626 Polymerase A arginine-rich C-terminus 317 440 6.4E-41 T 06-07-2017 IPR025866 Polymerase A arginine-rich C-terminal domain CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 22 442 7.7E-157 T 06-07-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 204 264 1.1E-18 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Gene3D G3DSA:3.30.460.10 34 176 4.2E-49 T 06-07-2017 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Pfam PF01743 Poly A polymerase head domain 52 177 1.7E-34 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 SUPERFAMILY SSF81301 26 174 1.09E-40 T 06-07-2017 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Gene3D G3DSA:1.10.3090.10 177 408 7.7E-50 T 06-07-2017 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 SUPERFAMILY SSF81891 175 406 5.49E-53 T 06-07-2017 CAL12_RS06375 7125de33c6e31afb2464611df4cd11c6 458 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 16 441 37.185 T 06-07-2017 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 CAL12_RS16445 86a975095b355582896b02715b2158de 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16445 86a975095b355582896b02715b2158de 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.6E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16445 86a975095b355582896b02715b2158de 192 Gene3D G3DSA:1.10.357.10 2 190 3.5E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16445 86a975095b355582896b02715b2158de 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS16445 86a975095b355582896b02715b2158de 192 SUPERFAMILY SSF46689 3 79 8.03E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16445 86a975095b355582896b02715b2158de 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS09350 f9d2324ddc2eb17faccacc170ccf79d9 349 Gene3D G3DSA:3.30.1780.10 2 138 2.2E-36 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS09350 f9d2324ddc2eb17faccacc170ccf79d9 349 SUPERFAMILY SSF51735 2 336 8.59E-94 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09350 f9d2324ddc2eb17faccacc170ccf79d9 349 Gene3D G3DSA:3.40.50.720 139 296 1.4E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09350 f9d2324ddc2eb17faccacc170ccf79d9 349 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 13 314 2.7E-98 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 Gene3D G3DSA:3.30.70.250 123 194 1.0E-29 T 06-07-2017 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 PIRSF PIRSF000446 1 308 2.5E-105 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 SUPERFAMILY SSF52151 2 126 2.96E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 SUPERFAMILY SSF52151 196 295 2.96E-68 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 Gene3D G3DSA:3.40.366.10 2 120 7.9E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 Gene3D G3DSA:3.40.366.10 195 295 7.9E-63 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 Pfam PF00698 Acyl transferase domain 5 275 6.2E-35 T 06-07-2017 IPR014043 Acyl transferase CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 305 2.0E-32 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 288 4.2E-102 T 06-07-2017 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CAL12_RS08360 94f060fdd6565f2beccfd028033177aa 311 SUPERFAMILY SSF55048 126 195 3.66E-17 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAL12_RS24470 b8b00a6c5f56d1a030d913bd4cd046c2 257 SUPERFAMILY SSF52499 33 254 2.88E-47 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS24470 b8b00a6c5f56d1a030d913bd4cd046c2 257 Pfam PF00857 Isochorismatase family 53 252 3.7E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS24470 b8b00a6c5f56d1a030d913bd4cd046c2 257 Gene3D G3DSA:3.40.50.850 20 254 1.9E-63 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 Gene3D G3DSA:1.10.287.890 201 283 1.2E-34 T 06-07-2017 CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 305 29.583 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 291 4.1E-95 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 Gene3D G3DSA:3.40.50.300 4 172 1.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 SUPERFAMILY SSF52540 6 150 2.83E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 Pfam PF01715 IPP transferase 40 285 9.1E-87 T 06-07-2017 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 SUPERFAMILY SSF52540 146 238 1.17E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06395 09d3a2df2c8ab73809271fbd04c8b923 311 SUPERFAMILY SSF52540 5 36 1.17E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07180 2b464c35eb6c49de437a35e2bd9bc3e5 290 TIGRFAM TIGR02321 Pphn_pyruv_hyd: phosphonopyruvate hydrolase 1 290 1.6E-166 T 06-07-2017 IPR012649 Phosphonopyruvate hydrolase KEGG: 00440+3.11.1.3 CAL12_RS07180 2b464c35eb6c49de437a35e2bd9bc3e5 290 SUPERFAMILY SSF51621 1 289 1.79E-77 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS07180 2b464c35eb6c49de437a35e2bd9bc3e5 290 Gene3D G3DSA:3.20.20.60 2 273 3.2E-73 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS07180 2b464c35eb6c49de437a35e2bd9bc3e5 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 253 2.2E-70 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Hamap MF_01588 DNA ligase [ligA]. 8 697 53.543 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00292 623 700 1.9E-10 T 06-07-2017 IPR001357 BRCT domain CAL12_RS19555 509677984c24138643c4182274536642 701 SUPERFAMILY SSF56091 8 348 2.72E-113 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00532 9 480 1.3E-262 T 06-07-2017 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 10 243 9.0E-97 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 261 350 1.2E-21 T 06-07-2017 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF12826 Helix-hairpin-helix motif 542 605 1.4E-25 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:2.40.50.140 351 422 8.5E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00278 544 563 300.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00278 576 595 7.9 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00278 512 531 4.5 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 SMART SM00278 478 497 23.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 17 692 2.7E-247 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 353 430 5.6E-37 T 06-07-2017 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:1.10.150.20 467 534 3.6E-27 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 626 697 1.5E-11 T 06-07-2017 IPR001357 BRCT domain CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 440 466 2.5E-11 T 06-07-2017 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 SUPERFAMILY SSF50249 349 432 7.37E-30 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS19555 509677984c24138643c4182274536642 701 Pfam PF14520 Helix-hairpin-helix domain 479 531 2.2E-8 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:3.30.470.30 131 283 8.9E-52 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:1.10.150.20 536 615 8.1E-33 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 SUPERFAMILY SSF47781 436 615 1.48E-61 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS19555 509677984c24138643c4182274536642 701 SUPERFAMILY SSF52113 624 697 4.42E-17 T 06-07-2017 IPR001357 BRCT domain CAL12_RS19555 509677984c24138643c4182274536642 701 PIRSF PIRSF001604 2 701 6.2E-240 T 06-07-2017 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CAL12_RS19555 509677984c24138643c4182274536642 701 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 363 378 - T 06-07-2017 IPR033136 NAD-dependent DNA ligase, conserved site CAL12_RS19555 509677984c24138643c4182274536642 701 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 127 156 - T 06-07-2017 IPR018239 NAD-dependent DNA ligase, active site CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:1.10.287.610 7 73 5.7E-31 T 06-07-2017 CAL12_RS19555 509677984c24138643c4182274536642 701 Gene3D G3DSA:3.40.50.10190 626 697 9.9E-22 T 06-07-2017 IPR001357 BRCT domain CAL12_RS08865 11cce185cf6df5c9c232a68398ab58de 119 Pfam PF00486 Transcriptional regulatory protein, C terminal 40 111 8.0E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS08865 11cce185cf6df5c9c232a68398ab58de 119 SMART SM00862 40 111 1.3E-12 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS08865 11cce185cf6df5c9c232a68398ab58de 119 SUPERFAMILY SSF46894 30 113 7.94E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS08865 11cce185cf6df5c9c232a68398ab58de 119 Gene3D G3DSA:1.10.10.10 36 112 2.4E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 189 3.3E-17 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 189 2.5E-28 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 Gene3D G3DSA:3.40.50.1000 93 219 5.2E-46 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 Gene3D G3DSA:3.40.50.1000 3 20 5.2E-46 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 171 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 178 191 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 133 149 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 102 115 2.3E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS14120 9e6bc032a548de2f302e96725f3ae62b 236 SUPERFAMILY SSF56784 6 218 2.85E-50 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 SUPERFAMILY SSF56935 141 815 9.57E-130 T 06-07-2017 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 Gene3D G3DSA:2.170.130.10 141 294 5.1E-35 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 Pfam PF00593 TonB dependent receptor 583 814 6.6E-29 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 Pfam PF07715 TonB-dependent Receptor Plug Domain 181 282 1.5E-21 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 SMART SM00965 88 139 3.7E-7 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 183 815 6.7E-100 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS11010 eefa033ead066d046a4637fd92c22cdf 815 Gene3D G3DSA:2.40.170.20 297 815 5.8E-132 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 Pfam PF00117 Glutamine amidotransferase class-I 6 219 8.5E-17 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 PIRSF PIRSF000495 2 224 5.9E-62 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 222 33.523 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 Gene3D G3DSA:3.40.50.880 3 222 1.0E-79 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 SUPERFAMILY SSF52317 4 222 2.58E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS00825 d246c046b8788d1af78134342f7ada26 224 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 131 221 7.9E-32 T 06-07-2017 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 4.6E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 4.6E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 4.6E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 4.6E-33 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Gene3D G3DSA:1.20.200.10 138 415 2.1E-102 T 06-07-2017 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 459 3.7E-233 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Gene3D G3DSA:1.10.40.30 416 462 3.2E-31 T 06-07-2017 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Pfam PF00206 Lyase 11 341 9.5E-111 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 SUPERFAMILY SSF48557 3 459 1.47E-152 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Gene3D G3DSA:1.10.275.10 1 137 3.1E-60 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 91.087 T 06-07-2017 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 Pfam PF10415 Fumarase C C-terminus 407 460 1.0E-25 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 4.8E-6 T 06-07-2017 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 4.8E-6 T 06-07-2017 CAL12_RS06420 6e228a98541156639aa2018e0fb53047 465 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 4.8E-6 T 06-07-2017 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 SMART SM01005 255 380 8.1E-63 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 SUPERFAMILY SSF50621 249 378 1.92E-44 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 42 58 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 173 184 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 271 286 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 76 94 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 214 241 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 136 148 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 288 303 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 362 375 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 PRINTS PR00992 Alanine racemase signature 309 326 3.5E-56 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 SUPERFAMILY SSF51419 9 256 7.41E-50 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 Gene3D G3DSA:2.40.37.10 238 378 8.0E-54 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 TIGRFAM TIGR00492 alr: alanine racemase 4 380 5.8E-94 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 Hamap MF_01201 Alanine racemase. 2 380 31.885 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 Gene3D G3DSA:3.20.20.10 12 237 2.0E-52 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 Pfam PF01168 Alanine racemase, N-terminal domain 9 241 2.5E-56 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS18180 9ddadc6c3bf2e21babba8abb34b244c6 381 Pfam PF00842 Alanine racemase, C-terminal domain 255 377 4.2E-38 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 38 327 1.7E-97 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 PIRSF PIRSF004486 1 329 3.0E-92 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 328 36.237 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 Gene3D G3DSA:1.10.150.170 132 235 6.3E-36 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 SUPERFAMILY SSF81799 134 233 1.29E-33 T 06-07-2017 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 Pfam PF01795 MraW methylase family 3 327 3.0E-99 T 06-07-2017 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 SUPERFAMILY SSF53335 233 327 7.22E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 SUPERFAMILY SSF53335 35 133 7.22E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 Gene3D G3DSA:3.40.50.150 236 329 8.3E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22445 e9bc357bd573086cb5d70f105c2dcd78 359 Gene3D G3DSA:3.40.50.150 43 130 8.3E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS04750 7332dab22f5b34ca64dff6344011b4a7 306 Gene3D G3DSA:3.20.20.70 10 287 1.5E-14 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS04750 7332dab22f5b34ca64dff6344011b4a7 306 SUPERFAMILY SSF51569 7 285 1.03E-10 T 06-07-2017 CAL12_RS04750 7332dab22f5b34ca64dff6344011b4a7 306 Pfam PF09863 Uncharacterized protein conserved in bacteria (DUF2090) 7 301 4.0E-38 T 06-07-2017 IPR018659 Protein of unknown function DUF2090 CAL12_RS04125 22f82779f4b0ab83dbaadbe1f36073ae 273 SUPERFAMILY SSF52540 27 250 4.87E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04125 22f82779f4b0ab83dbaadbe1f36073ae 273 Pfam PF00005 ABC transporter 43 181 3.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04125 22f82779f4b0ab83dbaadbe1f36073ae 273 SMART SM00382 51 232 1.5E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04125 22f82779f4b0ab83dbaadbe1f36073ae 273 Gene3D G3DSA:3.40.50.300 22 229 3.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25205 9c4aca563cef8a6a281fae61998ccdca 321 PIRSF PIRSF017082 1 321 5.0E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25205 9c4aca563cef8a6a281fae61998ccdca 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 317 7.0E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25205 9c4aca563cef8a6a281fae61998ccdca 321 SUPERFAMILY SSF53850 111 279 1.68E-16 T 06-07-2017 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 1.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 Gene3D G3DSA:3.40.190.10 179 264 1.4E-19 T 06-07-2017 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 Gene3D G3DSA:1.10.10.10 6 83 2.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 Pfam PF03466 LysR substrate binding domain 91 296 2.6E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 SUPERFAMILY SSF53850 93 300 8.69E-44 T 06-07-2017 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 SUPERFAMILY SSF46785 5 115 1.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00025 d9341a51753982809c1adff2d54022bd 307 Gene3D G3DSA:3.40.190.10 84 178 6.7E-10 T 06-07-2017 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 SUPERFAMILY SSF46785 11 122 1.31E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 SUPERFAMILY SSF53850 99 312 1.63E-28 T 06-07-2017 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 2.1E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 Pfam PF03466 LysR substrate binding domain 98 308 9.5E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 Gene3D G3DSA:1.10.10.10 12 98 5.7E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 Gene3D G3DSA:3.40.190.10 204 272 2.7E-7 T 06-07-2017 CAL12_RS12695 70012c44033f072a48eb7a90438bfe63 327 Gene3D G3DSA:3.40.190.10 100 203 5.2E-17 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 SUPERFAMILY SSF55979 8 120 1.23E-21 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 9 122 7.9E-28 T 06-07-2017 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Gene3D G3DSA:3.10.150.10 129 252 9.4E-38 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 370 1.6E-30 T 06-07-2017 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Gene3D G3DSA:3.10.150.10 253 371 8.6E-37 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Gene3D G3DSA:3.10.150.10 7 123 1.4E-25 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 247 9.9E-33 T 06-07-2017 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 SUPERFAMILY SSF55979 129 248 1.76E-28 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 SUPERFAMILY SSF55979 250 371 8.11E-34 T 06-07-2017 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 PIRSF PIRSF000804 3 371 6.2E-111 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 SMART SM00480 20 367 3.5E-105 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS00010 314281b2963c5eb1b2d2701fa919b33a 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 8 370 1.2E-91 T 06-07-2017 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS15415 36037491ea954b107c19f82b4f103808 699 Pfam PF00593 TonB dependent receptor 440 697 6.3E-28 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS15415 36037491ea954b107c19f82b4f103808 699 Gene3D G3DSA:2.40.170.20 168 699 5.4E-74 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS15415 36037491ea954b107c19f82b4f103808 699 SUPERFAMILY SSF56935 52 699 1.26E-92 T 06-07-2017 CAL12_RS15415 36037491ea954b107c19f82b4f103808 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 166 2.3E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS15415 36037491ea954b107c19f82b4f103808 699 Gene3D G3DSA:2.170.130.10 42 167 1.8E-25 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 SUPERFAMILY SSF51735 3 259 2.99E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 Gene3D G3DSA:3.40.50.720 1 258 2.0E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.4E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 4.3E-103 T 06-07-2017 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 9.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.3E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20960 561ed0b604e028c7d8ad7d7c80736979 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 258 4.7E-54 T 06-07-2017 CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 Pfam PF07729 FCD domain 84 204 3.0E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 SUPERFAMILY SSF46785 8 75 5.85E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 SMART SM00345 13 71 7.1E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 Gene3D G3DSA:1.10.10.10 3 71 2.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 SUPERFAMILY SSF48008 82 206 1.75E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 Gene3D G3DSA:1.20.120.530 80 207 5.0E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 SMART SM00895 81 205 4.0E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03055 eb356daab9d2de2dcb3345e68b6530aa 208 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.1E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 SUPERFAMILY SSF53448 5 227 4.06E-49 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 225 5.8E-56 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 225 2.3E-58 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 06-07-2017 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 Gene3D G3DSA:3.90.550.10 5 227 4.1E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS19610 f0604cc3fa968d638daaf76cd0d02dac 227 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 226 26.865 T 06-07-2017 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SMART SM00533 274 593 4.1E-81 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Gene3D G3DSA:1.10.1420.10 254 470 1.0E-48 T 06-07-2017 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Pfam PF00488 MutS domain V 612 798 1.6E-78 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Pfam PF05192 MutS domain III 261 561 1.3E-34 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SUPERFAMILY SSF48334 258 567 3.14E-81 T 06-07-2017 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Gene3D G3DSA:3.40.1170.10 1 111 6.1E-45 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 856 23.89 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Pfam PF05188 MutS domain II 121 244 2.4E-18 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Gene3D G3DSA:3.30.420.110 119 246 1.5E-35 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SUPERFAMILY SSF53150 108 271 1.03E-35 T 06-07-2017 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 861 0.0 T 06-07-2017 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SUPERFAMILY SSF55271 1 106 1.26E-37 T 06-07-2017 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 689 705 - T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SUPERFAMILY SSF52540 569 798 1.31E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 SMART SM00534 608 795 2.7E-102 T 06-07-2017 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Gene3D G3DSA:3.40.50.300 571 798 1.3E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Pfam PF01624 MutS domain I 1 110 1.7E-38 T 06-07-2017 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 CAL12_RS07415 bf24328a45e1646a9d9bac8bf51bfc55 865 Pfam PF05190 MutS family domain IV 430 521 5.7E-28 T 06-07-2017 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 SUPERFAMILY SSF56935 34 730 7.82E-125 T 06-07-2017 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 76 729 4.9E-108 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 Pfam PF07715 TonB-dependent Receptor Plug Domain 74 175 6.4E-16 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 Gene3D G3DSA:2.40.170.20 192 730 9.5E-125 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 Gene3D G3DSA:2.170.130.10 54 184 2.6E-35 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS06645 e661a855875d2dfb435abc0140ba94f7 730 Pfam PF00593 TonB dependent receptor 491 729 9.2E-30 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 SUPERFAMILY SSF88946 6 84 3.26E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 Gene3D G3DSA:1.10.10.10 97 158 8.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 156 2.0E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 Gene3D G3DSA:1.10.1740.10 4 74 5.1E-18 T 06-07-2017 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 Pfam PF08281 Sigma-70, region 4 104 154 2.4E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 SUPERFAMILY SSF88659 98 158 4.86E-17 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS13235 ab7c806b85bf460ed7bf37e16f3d1638 188 Pfam PF04542 Sigma-70 region 2 7 73 2.2E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 SUPERFAMILY SSF53067 2 122 1.1E-27 T 06-07-2017 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 318 4.6E-130 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 1.1E-48 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 Gene3D G3DSA:3.30.420.40 1 159 8.1E-47 T 06-07-2017 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 Pfam PF00814 Glycoprotease family 24 312 2.3E-98 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 SUPERFAMILY SSF53067 101 313 8.74E-44 T 06-07-2017 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 340 61.177 T 06-07-2017 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS15995 a2039907be27749a454046f1baa84368 347 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 311 1.5E-111 T 06-07-2017 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 Pfam PF07729 FCD domain 93 214 1.7E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 SMART SM00895 93 215 8.8E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 SUPERFAMILY SSF46785 22 87 1.18E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 SMART SM00345 25 83 1.1E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 SUPERFAMILY SSF48008 89 219 3.92E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 1.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 Gene3D G3DSA:1.10.10.10 23 84 4.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14710 2f461b2bc51d78a81b840dcd6a20dc09 234 Gene3D G3DSA:1.20.120.530 87 224 1.9E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 SUPERFAMILY SSF54506 168 293 1.96E-44 T 06-07-2017 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 9 294 36.627 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 Gene3D G3DSA:3.10.310.10 127 281 9.4E-47 T 06-07-2017 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 SUPERFAMILY SSF54506 10 138 5.34E-45 T 06-07-2017 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 72 86 - T 06-07-2017 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 10 291 6.5E-82 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 Pfam PF01678 Diaminopimelate epimerase 175 285 4.7E-25 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 Pfam PF01678 Diaminopimelate epimerase 11 128 2.1E-31 T 06-07-2017 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CAL12_RS26695 b20291db656dfb9f8191340137394e9c 305 Gene3D G3DSA:3.10.310.10 6 126 3.1E-49 T 06-07-2017 CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.0E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 9.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 9.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 9.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 Gene3D G3DSA:3.40.50.720 1 246 6.3E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 180 7.9E-5 T 06-07-2017 CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.9E-64 T 06-07-2017 CAL12_RS10540 0f82c510c6473170e5dfbc29770341d6 248 SUPERFAMILY SSF51735 5 246 2.38E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 Gene3D G3DSA:3.90.1150.10 264 395 3.2E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 31 392 1.4E-95 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 PIRSF PIRSF001434 1 396 3.2E-118 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 Gene3D G3DSA:3.40.640.10 7 262 2.4E-68 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 SUPERFAMILY SSF53383 43 394 1.58E-92 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS00555 a7cb7c80048f6ce7decfde0acd6d65b8 401 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 19 394 1.3E-112 T 06-07-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 Gene3D G3DSA:1.10.1040.10 169 298 1.4E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 SUPERFAMILY SSF51735 8 164 4.43E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 162 3.9E-37 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 Gene3D G3DSA:3.40.50.720 6 165 4.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 PIRSF PIRSF000103 1 299 6.1E-61 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 SUPERFAMILY SSF48179 168 298 6.57E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS06745 9fa21a637f16d318182e580185a46807 308 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 169 289 1.3E-37 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:2.40.30.110 903 1002 2.4E-19 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.50.50.60 168 286 2.1E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.50.50.60 416 479 2.1E-22 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 101 3.2E-24 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 190 2.1E-6 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 298 2.1E-6 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 SUPERFAMILY SSF101790 898 1001 8.01E-16 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PIRSF PIRSF037980 1 1002 0.0 T 06-07-2017 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 3 1001 0.0 T 06-07-2017 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 SUPERFAMILY SSF103025 608 895 4.55E-97 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.30.1360.120 763 857 1.1E-29 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.30.1360.120 609 668 1.1E-29 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 170 431 3.1E-14 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 192 1.6E-9 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 349 1.6E-9 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 292 1.6E-9 T 06-07-2017 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Pfam PF01571 Aminomethyltransferase folate-binding domain 614 878 2.0E-79 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.50.50.60 287 414 8.9E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 SUPERFAMILY SSF51905 159 477 2.46E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 887 989 2.0E-13 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAL12_RS06130 2f359d5b480b77413a890445e2148503 1003 Gene3D G3DSA:3.30.70.1400 669 754 1.1E-27 T 06-07-2017 CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 Gene3D G3DSA:3.40.190.10 180 252 2.4E-6 T 06-07-2017 CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 Gene3D G3DSA:3.40.190.10 91 179 3.7E-20 T 06-07-2017 CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 SUPERFAMILY SSF53850 88 296 3.08E-37 T 06-07-2017 CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 SUPERFAMILY SSF46785 2 110 2.91E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 Pfam PF03466 LysR substrate binding domain 87 291 2.3E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 7.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14180 dd2b7b9e2cbea62e17019eb566789259 311 Gene3D G3DSA:1.10.10.10 2 85 3.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11580 74222e62497783b9c3232b72f78560b7 255 Gene3D G3DSA:3.40.225.10 19 223 3.6E-55 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS11580 74222e62497783b9c3232b72f78560b7 255 SUPERFAMILY SSF53639 19 224 7.46E-55 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS11580 74222e62497783b9c3232b72f78560b7 255 SMART SM01007 24 205 7.8E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS11580 74222e62497783b9c3232b72f78560b7 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 24 204 3.7E-41 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS25380 02155e6927080deb1352a9f272474348 189 Gene3D G3DSA:2.40.128.20 9 183 8.9E-47 T 06-07-2017 IPR012674 Calycin CAL12_RS25380 02155e6927080deb1352a9f272474348 189 PRINTS PR01171 Bacterial lipocalin signature 170 180 4.9E-9 T 06-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 CAL12_RS25380 02155e6927080deb1352a9f272474348 189 PRINTS PR01171 Bacterial lipocalin signature 111 125 4.9E-9 T 06-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 CAL12_RS25380 02155e6927080deb1352a9f272474348 189 PRINTS PR01171 Bacterial lipocalin signature 143 154 4.9E-9 T 06-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 CAL12_RS25380 02155e6927080deb1352a9f272474348 189 PRINTS PR01171 Bacterial lipocalin signature 41 55 4.9E-9 T 06-07-2017 IPR002446 Lipocalin, bacterial GO:0005215 CAL12_RS25380 02155e6927080deb1352a9f272474348 189 SUPERFAMILY SSF50814 32 183 1.12E-37 T 06-07-2017 IPR011038 Calycin-like CAL12_RS25380 02155e6927080deb1352a9f272474348 189 PIRSF PIRSF036893 5 188 3.6E-49 T 06-07-2017 IPR022271 Lipocalin, ApoD type CAL12_RS25380 02155e6927080deb1352a9f272474348 189 Pfam PF08212 Lipocalin-like domain 41 181 1.6E-43 T 06-07-2017 IPR000566 Lipocalin/cytosolic fatty-acid binding domain CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 SMART SM00382 42 229 1.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 PIRSF PIRSF039085 14 256 3.9E-98 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 SUPERFAMILY SSF52540 18 250 1.39E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 Gene3D G3DSA:3.40.50.300 16 253 1.8E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14465 f8018dcc972266496bb5bf769c60002f 256 Pfam PF00005 ABC transporter 33 181 7.3E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Gene3D G3DSA:3.40.190.10 174 268 2.5E-21 T 06-07-2017 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Pfam PF03466 LysR substrate binding domain 96 298 3.1E-17 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Gene3D G3DSA:1.10.10.10 2 86 3.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 SUPERFAMILY SSF46785 5 86 5.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Gene3D G3DSA:3.40.190.10 91 173 5.7E-29 T 06-07-2017 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Gene3D G3DSA:3.40.190.10 273 300 5.7E-29 T 06-07-2017 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 SUPERFAMILY SSF53850 91 296 2.31E-36 T 06-07-2017 CAL12_RS02770 03a135c3314fa7a449a3134472f0f9cb 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 8.9E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01130 3eb7d6159e3c0970b4d4aeea0027eeec 257 PIRSF PIRSF015736 1 252 3.3E-72 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS01130 3eb7d6159e3c0970b4d4aeea0027eeec 257 Hamap MF_00943 Maleate isomerase [maiA]. 5 251 50.08 T 06-07-2017 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 Gene3D G3DSA:3.90.226.10 21 286 1.3E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 Pfam PF01039 Carboxyl transferase domain 100 243 2.5E-12 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 2.4E-39 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 2.4E-39 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 2.4E-39 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 2.4E-39 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 2.4E-39 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 284 3.8E-124 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 37.636 T 06-07-2017 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS08270 e560886690e4933a11dfcc500a107a30 291 SUPERFAMILY SSF52096 27 284 1.23E-81 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 345 2.0E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Pfam PF13426 PAS domain 156 258 2.4E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Pfam PF13426 PAS domain 29 130 4.4E-9 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Gene3D G3DSA:3.30.565.10 347 509 7.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00086 89 131 4.2 T 06-07-2017 IPR001610 PAC motif CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00086 217 259 1.3 T 06-07-2017 IPR001610 PAC motif CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 266 1.7E-22 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 28 138 2.2E-11 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SUPERFAMILY SSF55874 336 509 3.14E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Pfam PF00072 Response regulator receiver domain 532 643 4.1E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00091 15 84 0.03 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00091 143 210 3.4E-4 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 508 4.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 489 4.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 468 4.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 454 4.7E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Gene3D G3DSA:3.30.450.20 141 257 1.0E-26 T 06-07-2017 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SUPERFAMILY SSF47384 271 344 2.55E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SUPERFAMILY SSF52172 531 654 1.42E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00387 388 511 5.5E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Gene3D G3DSA:3.30.450.20 27 140 2.1E-14 T 06-07-2017 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Gene3D G3DSA:3.40.50.2300 529 654 4.9E-30 T 06-07-2017 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SUPERFAMILY SSF55785 130 257 2.9E-25 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00448 530 643 1.3E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SUPERFAMILY SSF55785 28 140 1.33E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 SMART SM00388 281 347 5.9E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 389 509 8.6E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03650 bc7ee36bb2d6836eaa88eaa8dcda553b 656 Gene3D G3DSA:1.10.287.130 270 310 2.9E-4 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 SUPERFAMILY SSF52922 723 877 1.43E-38 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 SUPERFAMILY SSF52518 490 717 2.1E-93 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 Gene3D G3DSA:3.40.50.970 71 484 2.9E-140 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 Gene3D G3DSA:3.40.50.970 490 721 1.2E-110 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 149 312 9.3E-7 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 SUPERFAMILY SSF52518 71 484 3.63E-123 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 PIRSF PIRSF000156 12 896 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 Gene3D G3DSA:3.40.50.920 727 879 3.7E-51 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 SMART SM00861 510 715 0.01 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 TIGRFAM TIGR03186 AKGDH_not_PDH: alpha-ketoglutarate dehydrogenase 19 901 0.0 T 06-07-2017 IPR017600 Alpha-ketoglutarate dehydrogenase CAL12_RS15790 2c7e4fced361c37dc33afcb5db787133 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 19 876 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 117 141 - T 06-07-2017 IPR020458 Zinc finger, DksA/TraR C4-type conserved site CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 112 146 1.0E-10 T 06-07-2017 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 32 153 28.337 T 06-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 SUPERFAMILY SSF57716 114 152 1.85E-8 T 06-07-2017 CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 SUPERFAMILY SSF109635 20 113 1.31E-28 T 06-07-2017 CAL12_RS26735 2122e7a5906f7b46fc3877ce3e640d4e 154 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 36 144 1.3E-42 T 06-07-2017 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Gene3D G3DSA:3.30.1360.70 6 111 8.7E-30 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Gene3D G3DSA:3.40.50.620 118 447 6.0E-106 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Pfam PF05746 DALR anticodon binding domain 444 561 1.4E-33 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 SMART SM01016 7 93 6.0E-33 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 11 93 6.6E-22 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 131 140 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 SUPERFAMILY SSF47323 439 561 4.25E-35 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 SMART SM00836 444 561 5.1E-49 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Pfam PF00750 tRNA synthetases class I (R) 105 406 1.1E-24 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 561 25.421 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 20 561 1.4E-126 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 SUPERFAMILY SSF55190 6 113 3.79E-21 T 06-07-2017 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 311 332 2.2E-22 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 160 173 2.2E-22 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 136 152 2.2E-22 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 PRINTS PR01038 Arginyl-tRNA synthetase signature 121 136 2.2E-22 T 06-07-2017 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 Gene3D G3DSA:1.10.730.10 448 561 4.7E-42 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS00575 72612ec295601afb86a0a1850b233dba 561 SUPERFAMILY SSF52374 118 456 2.95E-84 T 06-07-2017 CAL12_RS06870 b37b2d7bf179f26fe462143a789d3761 268 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS06870 b37b2d7bf179f26fe462143a789d3761 268 Gene3D G3DSA:3.40.50.300 8 256 2.9E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06870 b37b2d7bf179f26fe462143a789d3761 268 SUPERFAMILY SSF52540 11 257 7.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06870 b37b2d7bf179f26fe462143a789d3761 268 Pfam PF00005 ABC transporter 26 186 1.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS06870 b37b2d7bf179f26fe462143a789d3761 268 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 1.9E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS04370 e6df0800e52a18d31b6439e1dfb07b9c 376 Pfam PF07690 Major Facilitator Superfamily 4 319 3.3E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS04370 e6df0800e52a18d31b6439e1dfb07b9c 376 Gene3D G3DSA:1.20.1250.20 191 359 3.3E-9 T 06-07-2017 CAL12_RS04370 e6df0800e52a18d31b6439e1dfb07b9c 376 Gene3D G3DSA:1.20.1250.20 3 164 2.1E-11 T 06-07-2017 CAL12_RS04370 e6df0800e52a18d31b6439e1dfb07b9c 376 SUPERFAMILY SSF103473 4 360 6.02E-33 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 240 250 4.8E-10 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 56 68 4.8E-10 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 70 81 4.8E-10 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 PRINTS PR00987 Glutamyl-tRNA synthetase signature 85 98 4.8E-10 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 SUPERFAMILY SSF52374 53 380 2.68E-94 T 06-07-2017 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:1.10.1160.10 298 373 4.8E-33 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 53 372 7.1E-103 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 53 586 1.2E-202 T 06-07-2017 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:3.40.50.620 53 121 1.8E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:3.40.50.620 242 297 1.8E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 586 51.156 T 06-07-2017 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:2.40.240.10 499 584 2.9E-24 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 375 565 2.7E-47 T 06-07-2017 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 SUPERFAMILY SSF50715 375 585 2.88E-63 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:2.40.240.10 383 498 1.2E-45 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS05525 852e8d4f8e5fc54e6eb8fc9d86d30364 589 Gene3D G3DSA:3.90.800.10 131 239 9.5E-44 T 06-07-2017 CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 3.9E-7 T 06-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Pfam PF00107 Zinc-binding dehydrogenase 189 258 4.4E-12 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 3.7E-28 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 SUPERFAMILY SSF51735 156 268 1.97E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 SUPERFAMILY SSF51735 297 363 1.97E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 SUPERFAMILY SSF50129 1 195 3.96E-57 T 06-07-2017 IPR011032 GroES-like CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Gene3D G3DSA:3.90.180.10 1 180 1.7E-54 T 06-07-2017 IPR011032 GroES-like CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 SMART SM00829 7 391 0.0014 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Gene3D G3DSA:3.40.50.720 181 257 1.3E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18580 137325a5ea171bf8f8ffc8279390e51c 402 Gene3D G3DSA:3.40.50.720 301 342 1.3E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 181 209 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 Gene3D G3DSA:3.40.50.720 41 284 6.9E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 47 64 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 232 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 249 269 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 213 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 133 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 184 1.8E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 213 3.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 133 3.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 182 3.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 SUPERFAMILY SSF51735 45 285 3.88E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16455 131c89b1d34a712a0203cfd08d1055c1 288 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 55 284 1.5E-64 T 06-07-2017 CAL12_RS16020 d83b01246e666946cc9debca9a231621 185 Pfam PF11188 Protein of unknown function (DUF2975) 66 182 2.4E-13 T 06-07-2017 IPR021354 Protein of unknown function DUF2975 CAL12_RS13195 72db47c2a75c2aa4658d03400440d414 543 Pfam PF01384 Phosphate transporter family 87 242 2.5E-33 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAL12_RS13195 72db47c2a75c2aa4658d03400440d414 543 Pfam PF01384 Phosphate transporter family 257 532 2.8E-43 T 06-07-2017 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CAL12_RS02430 e61f46156e035f61975ad8bc3c4c1efb 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 315 1.7E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02430 e61f46156e035f61975ad8bc3c4c1efb 317 Gene3D G3DSA:1.10.3720.10 89 311 9.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02430 e61f46156e035f61975ad8bc3c4c1efb 317 SUPERFAMILY SSF161098 90 300 1.96E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03555 4e1cd7b1a9dda934b4e7e6b5af49d582 462 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 435 1.5E-39 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 117 733 2.3E-280 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Pfam PF00128 Alpha amylase, catalytic domain 287 357 6.7E-7 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Gene3D G3DSA:2.60.40.1180 634 735 2.4E-36 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 109 736 44.449 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 133 216 4.8E-21 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 SUPERFAMILY SSF81296 146 204 1.05E-9 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Gene3D G3DSA:3.20.20.80 255 621 9.5E-89 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Gene3D G3DSA:2.60.40.10 121 229 9.9E-37 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Gene3D G3DSA:2.60.40.10 22 114 1.1E-13 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 SUPERFAMILY SSF81296 24 125 1.09E-16 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 SMART SM00642 274 628 2.6E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 SUPERFAMILY SSF51445 188 627 1.1E-110 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 SUPERFAMILY SSF51011 634 736 3.12E-35 T 06-07-2017 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 639 735 3.7E-25 T 06-07-2017 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAL12_RS16155 d7a9d76d808f94b8308c5385e8c99ee4 737 PIRSF PIRSF000463 14 737 1.1E-284 T 06-07-2017 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 Gene3D G3DSA:1.10.10.10 123 220 6.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 SUPERFAMILY SSF52172 1 170 4.41E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.2E-19 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 SMART SM00862 145 218 3.5E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-41 T 06-07-2017 CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 SMART SM00448 1 112 1.3E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS17545 6e804c29a2ed0e9d72d85d294a1e1609 223 Pfam PF00072 Response regulator receiver domain 3 112 4.0E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21120 eb5772faddb8101d435c7e5bc63198b0 458 Pfam PF07287 Protein of unknown function (DUF1446) 9 359 5.4E-122 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 CAL12_RS01715 ae6d96a7ae32c82f9bc7c5ad084f1a3a 108 SUPERFAMILY SSF69754 1 101 5.1E-33 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAL12_RS01715 ae6d96a7ae32c82f9bc7c5ad084f1a3a 108 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 3.3E-25 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAL12_RS01715 ae6d96a7ae32c82f9bc7c5ad084f1a3a 108 Gene3D G3DSA:3.30.160.100 1 95 2.8E-33 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAL12_RS01715 ae6d96a7ae32c82f9bc7c5ad084f1a3a 108 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 2.3E-31 T 06-07-2017 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CAL12_RS09535 4408b4657e34343bfe2256ae00bc326a 540 Gene3D G3DSA:1.25.40.10 267 389 3.9E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS09535 4408b4657e34343bfe2256ae00bc326a 540 Gene3D G3DSA:1.25.40.10 87 209 3.9E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS09535 4408b4657e34343bfe2256ae00bc326a 540 SUPERFAMILY SSF48452 267 390 1.66E-7 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS09535 4408b4657e34343bfe2256ae00bc326a 540 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 5 389 5.7E-85 T 06-07-2017 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 CAL12_RS09535 4408b4657e34343bfe2256ae00bc326a 540 Pfam PF07219 HemY protein N-terminus 26 133 3.6E-28 T 06-07-2017 IPR010817 HemY, N-terminal CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 SMART SM00421 143 200 2.3E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 Pfam PF00072 Response regulator receiver domain 10 119 4.4E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 SUPERFAMILY SSF52172 8 157 5.98E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 4.6E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 Gene3D G3DSA:3.40.50.2300 9 151 2.6E-35 T 06-07-2017 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.3E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 Gene3D G3DSA:1.10.10.10 152 202 3.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 SUPERFAMILY SSF46894 138 200 2.34E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS11730 1be638889a884bd347811d12f57b5ffb 208 SMART SM00448 8 119 1.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 SUPERFAMILY SSF56645 423 652 2.49E-61 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 641 788 8.6E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 371 2.4E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:1.10.540.10 423 531 4.0E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 536 629 1.8E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 423 530 1.0E-15 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 88 5.0E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:2.40.110.10 137 217 2.0E-9 T 06-07-2017 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:2.40.110.10 534 629 1.6E-30 T 06-07-2017 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:1.20.140.10 630 792 1.3E-26 T 06-07-2017 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:1.20.140.10 218 372 4.1E-28 T 06-07-2017 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 SUPERFAMILY SSF47203 236 375 1.03E-30 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 SUPERFAMILY SSF47203 641 790 7.89E-18 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 SUPERFAMILY SSF56645 14 228 3.4E-31 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS18155 4e8731088d94fd9ac490209873dc252b 794 Gene3D G3DSA:1.10.540.10 14 101 7.3E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS08060 6d9b5979aafa6a5dcea2a3bb9a101c90 609 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 190 599 3.1E-95 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS08060 6d9b5979aafa6a5dcea2a3bb9a101c90 609 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 151 5.0E-29 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS08060 6d9b5979aafa6a5dcea2a3bb9a101c90 609 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 200 601 4.9E-88 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 SUPERFAMILY SSF53850 94 291 4.53E-28 T 06-07-2017 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 Gene3D G3DSA:3.40.190.10 181 263 1.1E-7 T 06-07-2017 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 Gene3D G3DSA:3.40.190.10 94 180 1.1E-16 T 06-07-2017 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 Gene3D G3DSA:1.10.10.10 6 90 9.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 Pfam PF03466 LysR substrate binding domain 92 290 1.7E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 SUPERFAMILY SSF46785 5 114 1.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04425 9f079e31ee0f855465ec4dbc16011c1f 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 SMART SM00422 1 70 5.6E-30 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 Gene3D G3DSA:1.10.1660.10 1 55 1.3E-23 T 06-07-2017 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 9.3E-53 T 06-07-2017 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 Pfam PF00376 MerR family regulatory protein 2 39 3.5E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 Gene3D G3DSA:1.10.1660.10 56 128 4.7E-29 T 06-07-2017 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.9E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.9E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 6.9E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 SUPERFAMILY SSF46955 1 126 2.09E-38 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS11675 9b5e00759ef7ee05a5eb4a86d9560333 129 Pfam PF09278 MerR, DNA binding 44 108 1.0E-18 T 06-07-2017 IPR015358 Transcription regulator MerR, DNA binding CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 806 851 3.8E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 699 2.8E-10 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 648 1.2E-8 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 755 801 2.6E-11 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 749 7.6E-13 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 594 6.8E-10 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Gene3D G3DSA:3.30.1360.40 236 333 1.1E-39 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Gene3D G3DSA:2.120.10.90 542 851 3.2E-134 T 06-07-2017 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 508 1.8E-153 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 SUPERFAMILY SSF56719 30 523 5.36E-177 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Gene3D G3DSA:1.10.268.10 363 504 3.3E-48 T 06-07-2017 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 852 0.0 T 06-07-2017 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 SUPERFAMILY SSF101904 544 864 2.35E-111 T 06-07-2017 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Gene3D G3DSA:3.90.199.10 34 216 6.8E-85 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 SMART SM00434 11 506 7.4E-290 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS18955 d09fb1417091ceb1166c5c2318a9495a 885 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 853 24.016 T 06-07-2017 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 Gene3D G3DSA:1.25.20.10 95 452 1.1E-78 T 06-07-2017 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 Gene3D G3DSA:1.10.530.10 540 702 2.8E-43 T 06-07-2017 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 Pfam PF14718 Soluble lytic murein transglycosylase L domain 472 531 2.9E-9 T 06-07-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 Pfam PF01464 Transglycosylase SLT domain 551 655 1.6E-18 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 SUPERFAMILY SSF53955 549 705 6.86E-43 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 Gene3D G3DSA:1.10.1240.20 472 528 3.3E-6 T 06-07-2017 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CAL12_RS26575 34fc9ad200b22d90dd81ed1a5832a068 718 SUPERFAMILY SSF48435 94 541 4.18E-97 T 06-07-2017 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 CAL12_RS21395 54b12afbf455a221b5d75704a079302e 292 Gene3D G3DSA:3.90.850.10 72 291 1.1E-86 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS21395 54b12afbf455a221b5d75704a079302e 292 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 292 4.0E-71 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS21395 54b12afbf455a221b5d75704a079302e 292 SUPERFAMILY SSF56529 72 291 4.06E-78 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 Gene3D G3DSA:3.40.640.10 49 318 5.0E-106 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 SUPERFAMILY SSF53383 2 400 1.45E-119 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 Pfam PF00155 Aminotransferase class I and II 31 394 2.8E-79 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 PRINTS PR00799 Aspartate aminotransferase signature 276 301 5.1E-40 T 06-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 PRINTS PR00799 Aspartate aminotransferase signature 344 362 5.1E-40 T 06-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 PRINTS PR00799 Aspartate aminotransferase signature 209 221 5.1E-40 T 06-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CAL12_RS17195 8c4ddadfd16d08c9b7cac8479a653afc 401 PRINTS PR00799 Aspartate aminotransferase signature 178 197 5.1E-40 T 06-07-2017 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CAL12_RS15740 7953a494eb708daeb81ac7470d517b1c 464 Gene3D G3DSA:3.30.43.10 33 99 1.6E-11 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS15740 7953a494eb708daeb81ac7470d517b1c 464 Pfam PF08031 Berberine and berberine like 415 458 1.5E-13 T 06-07-2017 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CAL12_RS15740 7953a494eb708daeb81ac7470d517b1c 464 SUPERFAMILY SSF56176 17 207 1.64E-54 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS15740 7953a494eb708daeb81ac7470d517b1c 464 Gene3D G3DSA:3.30.465.10 100 207 4.1E-17 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS15740 7953a494eb708daeb81ac7470d517b1c 464 Pfam PF01565 FAD binding domain 43 177 2.9E-33 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 2.0E-60 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 5.3E-131 T 06-07-2017 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 06-07-2017 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 Gene3D G3DSA:3.40.50.720 1 163 6.3E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 SUPERFAMILY SSF51735 3 176 1.32E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PIRSF PIRSF000149 1 336 1.7E-137 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 SMART SM00846 3 155 6.7E-99 T 06-07-2017 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 1.1E-39 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 1.1E-39 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 1.1E-39 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 1.1E-39 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 1.1E-39 T 06-07-2017 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 Gene3D G3DSA:3.30.360.10 164 317 1.3E-70 T 06-07-2017 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 SUPERFAMILY SSF55347 155 316 9.82E-69 T 06-07-2017 CAL12_RS05015 3e1226e15846415f18ae75dd61ce55d7 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 2.0E-62 T 06-07-2017 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS08175 55a45b35cae84abfb5b2fd3f38e0830b 314 SUPERFAMILY SSF103481 196 293 6.28E-6 T 06-07-2017 CAL12_RS08175 55a45b35cae84abfb5b2fd3f38e0830b 314 SUPERFAMILY SSF103481 48 148 2.88E-15 T 06-07-2017 CAL12_RS08175 55a45b35cae84abfb5b2fd3f38e0830b 314 Pfam PF00892 EamA-like transporter family 16 146 2.2E-23 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS08175 55a45b35cae84abfb5b2fd3f38e0830b 314 Pfam PF00892 EamA-like transporter family 161 293 3.4E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS00295 8e36bf52565c5c6077ad99c5bdaa1f81 259 TIGRFAM TIGR03371 cellulose_yhjQ: cellulose synthase operon protein YhjQ 1 251 4.8E-69 T 06-07-2017 IPR017746 Cellulose synthase operon protein BcsQ CAL12_RS00295 8e36bf52565c5c6077ad99c5bdaa1f81 259 SUPERFAMILY SSF52540 2 251 3.13E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00295 8e36bf52565c5c6077ad99c5bdaa1f81 259 Pfam PF06564 Cellulose biosynthesis protein BcsQ 3 248 2.5E-39 T 06-07-2017 IPR017746 Cellulose synthase operon protein BcsQ CAL12_RS00295 8e36bf52565c5c6077ad99c5bdaa1f81 259 Gene3D G3DSA:3.40.50.300 2 252 2.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21085 cdafa82caf7e20ee9f5644e3230a6062 202 Pfam PF13649 Methyltransferase domain 47 127 3.5E-12 T 06-07-2017 CAL12_RS21085 cdafa82caf7e20ee9f5644e3230a6062 202 SUPERFAMILY SSF53335 4 188 4.34E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS21085 cdafa82caf7e20ee9f5644e3230a6062 202 Gene3D G3DSA:3.40.50.150 2 183 4.5E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 Pfam PF06144 DNA polymerase III, delta subunit 25 198 8.1E-22 T 06-07-2017 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 Gene3D G3DSA:3.40.50.300 5 145 2.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 Gene3D G3DSA:1.10.8.60 152 230 1.5E-33 T 06-07-2017 CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 SUPERFAMILY SSF48019 220 348 1.7E-26 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 344 1.1E-76 T 06-07-2017 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 Gene3D G3DSA:1.20.272.20 231 346 7.9E-31 T 06-07-2017 CAL12_RS08720 f900c3108d656a1a06be103268fae92a 352 SUPERFAMILY SSF52540 14 218 1.86E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 2.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 2.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 2.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 SMART SM00421 147 204 8.8E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 SUPERFAMILY SSF46894 146 205 9.18E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 202 8.4E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS11475 f62196b735e97bdd9d2579732a5ac705 209 Gene3D G3DSA:1.10.10.10 126 204 1.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 Gene3D G3DSA:3.90.380.10 179 378 7.5E-9 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 SUPERFAMILY SSF55961 161 377 2.43E-44 T 06-07-2017 CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 SUPERFAMILY SSF50022 8 154 8.51E-26 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 Pfam PF00355 Rieske [2Fe-2S] domain 71 135 1.7E-7 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 Gene3D G3DSA:2.102.10.10 41 159 1.8E-18 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS18315 8b18281f9fa34059c81545ced2e72617 384 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 180 378 4.5E-34 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Pfam PF00501 AMP-binding enzyme 19 416 6.8E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 SUPERFAMILY SSF56801 5 511 5.36E-144 T 06-07-2017 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Gene3D G3DSA:3.40.50.980 6 167 6.8E-33 T 06-07-2017 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 500 6.9E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Gene3D G3DSA:2.30.38.10 327 409 7.2E-28 T 06-07-2017 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Gene3D G3DSA:3.40.50.980 168 321 2.5E-40 T 06-07-2017 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 Gene3D G3DSA:3.30.300.30 411 509 1.4E-31 T 06-07-2017 CAL12_RS08830 35cc555f9776b1ce7565720a408a5f05 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS00490 4e6314bda4675babe5fe015146f4a89a 222 Gene3D G3DSA:1.10.3720.10 12 216 1.9E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00490 4e6314bda4675babe5fe015146f4a89a 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 216 8.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00490 4e6314bda4675babe5fe015146f4a89a 222 SUPERFAMILY SSF161098 15 202 1.42E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00490 4e6314bda4675babe5fe015146f4a89a 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 3.7E-27 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS16080 ba9db0a7641fe6a10c0616f2b194c1c6 334 Gene3D G3DSA:3.30.1780.10 6 144 4.6E-36 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS16080 ba9db0a7641fe6a10c0616f2b194c1c6 334 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 13 323 1.1E-59 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS16080 ba9db0a7641fe6a10c0616f2b194c1c6 334 Gene3D G3DSA:3.40.50.720 145 304 7.6E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16080 ba9db0a7641fe6a10c0616f2b194c1c6 334 PIRSF PIRSF001439 2 334 6.8E-87 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS16080 ba9db0a7641fe6a10c0616f2b194c1c6 334 SUPERFAMILY SSF51735 3 333 3.2E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 SUPERFAMILY SSF53474 65 353 3.21E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 Pfam PF00561 alpha/beta hydrolase fold 86 207 5.6E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 Gene3D G3DSA:3.40.50.1820 65 354 7.0E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 PRINTS PR00412 Epoxide hydrolase signature 173 186 1.0E-13 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 PRINTS PR00412 Epoxide hydrolase signature 332 354 1.0E-13 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 PRINTS PR00412 Epoxide hydrolase signature 111 126 1.0E-13 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 PRINTS PR00412 Epoxide hydrolase signature 159 172 1.0E-13 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS05840 8a5994cd2761a9618b0991736fa7d777 357 PRINTS PR00412 Epoxide hydrolase signature 91 109 1.0E-13 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 SUPERFAMILY SSF55298 157 284 3.93E-15 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 SUPERFAMILY SSF55298 305 424 5.34E-10 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 Gene3D G3DSA:3.30.1330.40 21 139 3.0E-12 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 Gene3D G3DSA:3.30.1330.40 307 420 1.0E-6 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 Gene3D G3DSA:3.30.1330.40 157 284 7.4E-18 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 Pfam PF01042 Endoribonuclease L-PSP 159 283 1.2E-7 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS04825 0a70f5e4cd04ff038f67221c84a3fa59 426 SUPERFAMILY SSF55298 19 137 1.73E-10 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 SUPERFAMILY SSF82861 642 728 4.58E-12 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 SUPERFAMILY SSF50182 730 789 2.13E-12 T 06-07-2017 IPR010920 LSM domain CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 SUPERFAMILY SSF82689 798 894 2.09E-14 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 Gene3D G3DSA:2.30.30.60 746 792 1.2E-11 T 06-07-2017 CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 Pfam PF00924 Mechanosensitive ion channel 688 887 1.2E-38 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAL12_RS19750 ec065cd4ec6889f5091e3977e8a53aa5 929 Gene3D G3DSA:3.30.70.100 801 885 1.9E-8 T 06-07-2017 CAL12_RS21400 9ac35f1bdd48713373c946bd25b10a05 326 SUPERFAMILY SSF53850 107 290 1.31E-17 T 06-07-2017 CAL12_RS21400 9ac35f1bdd48713373c946bd25b10a05 326 Gene3D G3DSA:3.40.190.10 128 243 1.8E-5 T 06-07-2017 CAL12_RS21400 9ac35f1bdd48713373c946bd25b10a05 326 PIRSF PIRSF017082 1 325 2.4E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21400 9ac35f1bdd48713373c946bd25b10a05 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.0E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Gene3D G3DSA:3.40.50.980 4 166 2.4E-26 T 06-07-2017 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Pfam PF00501 AMP-binding enzyme 7 407 4.9E-79 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Gene3D G3DSA:3.30.300.30 403 500 2.7E-26 T 06-07-2017 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 491 1.2E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 SUPERFAMILY SSF56801 4 503 1.7E-131 T 06-07-2017 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Gene3D G3DSA:3.40.50.980 167 317 2.5E-29 T 06-07-2017 CAL12_RS13945 6f2556a877f19e8550f5d4f510d8c16d 506 Gene3D G3DSA:2.30.38.10 325 397 7.3E-23 T 06-07-2017 CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 SMART SM00345 34 92 1.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 SUPERFAMILY SSF48008 101 231 3.4E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 66 1.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 66 82 1.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 92 1.1E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 Gene3D G3DSA:1.10.10.10 26 93 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 SUPERFAMILY SSF46785 29 96 2.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 Gene3D G3DSA:1.20.120.530 97 234 1.9E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 Pfam PF07729 FCD domain 102 223 2.7E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS26025 264c1a78a4f89abb931a2b2fa817dfa8 239 SMART SM00895 102 224 2.5E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 PRINTS PR01713 Nucleotide sugar epimerase signature 62 78 5.0E-9 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 PRINTS PR01713 Nucleotide sugar epimerase signature 319 336 5.0E-9 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 PRINTS PR01713 Nucleotide sugar epimerase signature 251 266 5.0E-9 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 PRINTS PR01713 Nucleotide sugar epimerase signature 275 290 5.0E-9 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 SUPERFAMILY SSF51735 36 356 5.07E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 Gene3D G3DSA:3.40.50.720 34 214 1.0E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 Pfam PF01370 NAD dependent epimerase/dehydratase family 36 281 1.1E-57 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS21920 af635c580ca10ed07b7590d6fcba9491 363 Gene3D G3DSA:3.90.25.10 215 342 1.2E-32 T 06-07-2017 CAL12_RS06905 0b0622e3bfb30640730ccad5cca20d03 640 SUPERFAMILY SSF54001 275 381 9.81E-10 T 06-07-2017 CAL12_RS06905 0b0622e3bfb30640730ccad5cca20d03 640 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 76 226 2.0E-18 T 06-07-2017 IPR024618 Domain of unknown function DUF3857 CAL12_RS06905 0b0622e3bfb30640730ccad5cca20d03 640 Pfam PF01841 Transglutaminase-like superfamily 278 355 2.0E-10 T 06-07-2017 IPR002931 Transglutaminase-like CAL12_RS04815 9db0fa4185be1870d860628d8e49f574 2176 SUPERFAMILY SSF103515 1871 2176 3.01E-43 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS04815 9db0fa4185be1870d860628d8e49f574 2176 SMART SM00869 1900 2166 2.9E-31 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS04815 9db0fa4185be1870d860628d8e49f574 2176 Gene3D G3DSA:2.40.128.130 1893 2176 5.2E-37 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 5 304 6.8E-55 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 Gene3D G3DSA:3.40.50.720 1 176 5.0E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 179 301 2.8E-21 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 Gene3D G3DSA:1.10.1040.10 179 302 8.3E-22 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 SUPERFAMILY SSF51735 1 129 5.6E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 150 1.1E-34 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS00415 88218f3cb21bda071d41a8d80714595e 307 SUPERFAMILY SSF48179 179 302 2.11E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 SUPERFAMILY SSF53850 90 293 1.46E-40 T 06-07-2017 CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 Pfam PF03466 LysR substrate binding domain 89 293 8.5E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.6E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 Gene3D G3DSA:3.40.190.10 91 174 5.2E-22 T 06-07-2017 CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 Gene3D G3DSA:1.10.10.10 3 85 4.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 Gene3D G3DSA:3.40.190.10 175 258 1.8E-17 T 06-07-2017 CAL12_RS05800 96e79ea5dea552e37e455ab0b4172a41 320 SUPERFAMILY SSF46785 4 110 1.36E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11105 405762aa94c953831ba601bb3f4f9f3d 423 Gene3D G3DSA:1.20.1250.20 228 419 6.1E-22 T 06-07-2017 CAL12_RS11105 405762aa94c953831ba601bb3f4f9f3d 423 SUPERFAMILY SSF103473 17 419 1.96E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS11105 405762aa94c953831ba601bb3f4f9f3d 423 Pfam PF07690 Major Facilitator Superfamily 33 273 1.0E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS11105 405762aa94c953831ba601bb3f4f9f3d 423 Gene3D G3DSA:1.20.1250.20 19 197 4.7E-24 T 06-07-2017 CAL12_RS11105 405762aa94c953831ba601bb3f4f9f3d 423 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 19 422 1.2E-126 T 06-07-2017 IPR026355 Oxalate/formate antiporter GO:0005215|GO:0006810|GO:0016021 CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 SUPERFAMILY SSF52518 7 184 2.58E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Gene3D G3DSA:3.40.50.970 8 184 4.4E-61 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Gene3D G3DSA:3.40.50.1220 189 337 1.4E-36 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 323 4.6E-28 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 175 5.6E-51 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 392 537 1.3E-45 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 SUPERFAMILY SSF52467 162 360 7.95E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 Gene3D G3DSA:3.40.50.970 366 548 2.2E-64 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS15800 92b98d258e722ce887306e56733acbb8 560 SUPERFAMILY SSF52518 368 548 5.72E-62 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20800 f524a236d262121211a9adbf434091b9 359 SUPERFAMILY SSF51182 13 349 8.58E-84 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS20800 f524a236d262121211a9adbf434091b9 359 Gene3D G3DSA:2.60.120.10 242 350 3.6E-29 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS20800 f524a236d262121211a9adbf434091b9 359 Gene3D G3DSA:2.60.120.10 42 192 5.0E-38 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS20800 f524a236d262121211a9adbf434091b9 359 Pfam PF07883 Cupin domain 95 163 2.2E-19 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS20800 f524a236d262121211a9adbf434091b9 359 Pfam PF07883 Cupin domain 266 331 8.4E-14 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 SUPERFAMILY SSF46785 17 133 2.72E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 81 5.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 Gene3D G3DSA:3.40.190.10 115 198 2.3E-27 T 06-07-2017 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 SUPERFAMILY SSF53850 111 313 9.23E-37 T 06-07-2017 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 Gene3D G3DSA:3.40.190.10 199 279 1.3E-23 T 06-07-2017 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 Gene3D G3DSA:1.10.10.10 22 106 1.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 Pfam PF03466 LysR substrate binding domain 110 311 2.6E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 5.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 59 70 5.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07710 414414b55398537f158a4932541f2a0b 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 59 5.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 Gene3D G3DSA:1.10.3360.10 303 400 7.6E-8 T 06-07-2017 IPR023289 VPA0735-like domain CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 SUPERFAMILY SSF160935 121 568 1.57E-94 T 06-07-2017 CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 Pfam PF06742 Protein of unknown function (DUF1214) 446 552 7.2E-26 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 Gene3D G3DSA:2.60.120.600 410 568 2.9E-39 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 Pfam PF06863 Protein of unknown function (DUF1254) 173 303 2.9E-30 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS27115 b765081bcf67ee89389ca37c0842fc23 569 Gene3D G3DSA:2.60.40.1610 191 302 2.7E-14 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS11135 b8cdada321128e5b017e8e0873131ead 320 SUPERFAMILY SSF53850 109 287 1.55E-14 T 06-07-2017 CAL12_RS11135 b8cdada321128e5b017e8e0873131ead 320 PIRSF PIRSF017082 1 320 7.3E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11135 b8cdada321128e5b017e8e0873131ead 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 317 1.5E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13510 59d59b6bc7024221b5ef0313c1bc7656 367 SUPERFAMILY SSF51395 1 352 8.64E-113 T 06-07-2017 CAL12_RS13510 59d59b6bc7024221b5ef0313c1bc7656 367 Gene3D G3DSA:3.20.20.70 1 345 1.0E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS13510 59d59b6bc7024221b5ef0313c1bc7656 367 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 340 6.3E-65 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SUPERFAMILY SSF50494 60 108 6.66E-67 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SUPERFAMILY SSF50494 136 304 6.66E-67 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SUPERFAMILY SSF50156 271 396 2.89E-23 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Gene3D G3DSA:2.30.42.10 431 517 9.2E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Gene3D G3DSA:2.30.42.10 315 411 1.9E-30 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SUPERFAMILY SSF50156 430 517 6.97E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Gene3D G3DSA:2.40.10.10 205 314 9.7E-43 T 06-07-2017 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 63 513 1.2E-145 T 06-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Pfam PF13180 PDZ domain 313 404 2.5E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Gene3D G3DSA:2.40.10.10 61 204 9.5E-39 T 06-07-2017 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SMART SM00228 313 395 9.7E-10 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 SMART SM00228 429 507 9.5E-4 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 213 237 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 353 365 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 245 262 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 173 193 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 152 164 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 PRINTS PR00834 HtrA/DegQ protease family signature 267 284 1.0E-53 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08400 92481b0d529ac7281d99fb8ba338402c 518 Pfam PF13365 Trypsin-like peptidase domain 143 274 1.8E-35 T 06-07-2017 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 377 6.8E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 SUPERFAMILY SSF56645 2 240 7.07E-78 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 6.2E-25 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Gene3D G3DSA:1.10.540.10 1 117 2.8E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Gene3D G3DSA:2.40.110.10 121 216 5.9E-40 T 06-07-2017 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 2.0E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 SUPERFAMILY SSF47203 225 378 1.77E-57 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 Gene3D G3DSA:1.20.140.10 217 380 9.7E-67 T 06-07-2017 CAL12_RS12245 15d35b5000c0506b5c2bbb21075bf3e7 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS01440 f41a2ea587ef31a1c6201d883f5ed961 131 SUPERFAMILY SSF50249 6 106 1.54E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS01440 f41a2ea587ef31a1c6201d883f5ed961 131 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 105 6.5E-12 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAL12_RS00975 5af04487dfe20637990c37960839eda7 339 PIRSF PIRSF006470 1 335 2.4E-116 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS00975 5af04487dfe20637990c37960839eda7 339 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 291 5.6E-82 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS00975 5af04487dfe20637990c37960839eda7 339 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 318 1.6E-93 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 Gene3D G3DSA:1.10.8.50 1 71 1.4E-27 T 06-07-2017 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.9E-50 T 06-07-2017 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 06-07-2017 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 SUPERFAMILY SSF46946 2 114 2.08E-42 T 06-07-2017 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 26.714 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.3E-30 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 Gene3D G3DSA:4.10.910.10 72 121 8.2E-25 T 06-07-2017 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27510 84a3f0354e290d24beca38a9a9442e8c 121 PIRSF PIRSF002134 1 121 1.6E-39 T 06-07-2017 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82714 183 265 1.02E-14 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:3.30.70.1430 40 142 4.6E-26 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 450 473 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 475 498 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 342 365 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 555 572 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 369 390 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 397 421 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 7.3E-74 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82866 827 1026 2.09E-42 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:1.20.1640.10 297 509 3.1E-56 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82866 302 502 1.02E-46 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:1.10.3850.10 809 1026 5.0E-54 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82714 717 800 1.09E-11 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 136 182 2.44E-20 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 280 336 2.44E-20 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:3.30.2090.10 716 800 3.2E-14 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:3.30.2090.10 182 261 1.2E-15 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Gene3D G3DSA:3.30.70.1430 570 656 4.1E-4 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 Pfam PF00873 AcrB/AcrD/AcrF family 4 1024 2.9E-303 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 674 715 3.4E-11 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 804 846 3.4E-11 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 568 660 1.05E-8 T 06-07-2017 CAL12_RS23240 dfb95965f0a1558baac070713326b04e 1061 SUPERFAMILY SSF82693 40 132 4.71E-20 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 199 247 - T 06-07-2017 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 33 113 5.9E-13 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 SUPERFAMILY SSF46626 276 367 5.25E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 236 253 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 174 195 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 218 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 102 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 218 235 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 102 122 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 PRINTS PR01166 Cytochrome c oxidase subunit II signature 124 143 2.2E-39 T 06-07-2017 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 SUPERFAMILY SSF49503 176 318 2.43E-52 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 SUPERFAMILY SSF49503 120 147 2.43E-52 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Gene3D G3DSA:1.10.287.90 33 119 1.6E-23 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 287 360 1.3E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 263 1.2E-57 T 06-07-2017 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 252 1.3E-37 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 SUPERFAMILY SSF81464 32 122 4.91E-25 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Gene3D G3DSA:2.60.40.420 120 300 5.8E-56 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS00990 e03fec3fd70d656eef4afd00ed79cb9b 386 Gene3D G3DSA:1.10.760.10 301 382 3.9E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Pfam PF13365 Trypsin-like peptidase domain 118 251 1.8E-34 T 06-07-2017 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Gene3D G3DSA:2.40.10.10 57 180 3.6E-36 T 06-07-2017 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 SMART SM00228 290 372 2.0E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 SMART SM00228 401 476 2.9E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Gene3D G3DSA:2.40.10.10 181 291 5.1E-42 T 06-07-2017 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 SUPERFAMILY SSF50494 56 280 7.07E-65 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 399 470 1.1E-8 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Pfam PF13180 PDZ domain 291 380 2.3E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 58 481 3.4E-145 T 06-07-2017 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 SUPERFAMILY SSF50156 248 373 2.63E-24 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 SUPERFAMILY SSF50156 401 484 2.37E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 222 239 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 330 342 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 244 261 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 PRINTS PR00834 HtrA/DegQ protease family signature 127 139 1.3E-48 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Gene3D G3DSA:2.30.42.10 292 386 6.1E-28 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS08945 ff9b71039cc838860ca90f1577fa9485 486 Gene3D G3DSA:2.30.42.10 399 485 2.9E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Pfam PF00005 ABC transporter 505 653 6.8E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 SUPERFAMILY SSF52540 479 712 2.56E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Pfam PF03412 Peptidase C39 family 23 143 7.5E-5 T 06-07-2017 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 SMART SM00382 514 700 9.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Gene3D G3DSA:3.40.50.300 487 712 1.9E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 24 717 7.9E-297 T 06-07-2017 IPR017750 ATPase, type I secretion system CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Gene3D G3DSA:3.90.70.10 21 145 1.0E-40 T 06-07-2017 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Pfam PF00664 ABC transporter transmembrane region 176 436 1.9E-21 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 SUPERFAMILY SSF90123 161 473 1.31E-52 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS11465 f806616ace299fb5938824bdffec31f9 723 Gene3D G3DSA:1.20.1560.10 161 473 2.9E-51 T 06-07-2017 CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 SUPERFAMILY SSF51735 4 139 8.92E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 Gene3D G3DSA:1.10.3730.10 162 255 4.2E-4 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 93 2.6E-16 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 255 1.2E-5 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 SUPERFAMILY SSF48179 162 255 2.55E-5 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 PIRSF PIRSF000193 2 257 1.1E-41 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAL12_RS20725 72001c390e4671495f8deb0da62b2a84 257 Gene3D G3DSA:3.40.50.720 4 145 4.1E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 Gene3D G3DSA:1.20.200.10 201 502 1.9E-124 T 06-07-2017 CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 Gene3D G3DSA:1.10.275.10 6 200 2.3E-69 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 8 500 1.5E-202 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 5 506 42.581 T 06-07-2017 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 SUPERFAMILY SSF48557 8 503 6.12E-187 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 141 156 - T 06-07-2017 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CAL12_RS03655 30a142b81b084259dfab6d827a6603b6 512 Pfam PF00221 Aromatic amino acid lyase 16 473 6.4E-183 T 06-07-2017 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 SUPERFAMILY SSF54862 3 76 1.02E-22 T 06-07-2017 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 2.1E-18 T 06-07-2017 IPR022569 Ferredoxin, C-terminal CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 Gene3D G3DSA:3.30.70.20 4 99 1.6E-20 T 06-07-2017 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-15 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-15 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-15 T 06-07-2017 IPR000813 7Fe ferredoxin GO:0009055 CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 Pfam PF00037 4Fe-4S binding domain 34 56 1.6E-6 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS08230 bc15f964c77d4df42b68caf8428bff98 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS13830 c32050fb5304d8354993656761b35f66 224 Pfam PF00578 AhpC/TSA family 51 196 1.3E-28 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS13830 c32050fb5304d8354993656761b35f66 224 Gene3D G3DSA:3.40.30.10 44 219 3.2E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS13830 c32050fb5304d8354993656761b35f66 224 SUPERFAMILY SSF52833 47 218 5.69E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 Pfam PF03466 LysR substrate binding domain 106 313 1.6E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 SUPERFAMILY SSF46785 19 129 1.36E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 Gene3D G3DSA:1.10.10.10 18 97 3.2E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 81 2.9E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 Gene3D G3DSA:3.40.190.10 108 195 2.5E-17 T 06-07-2017 CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 Gene3D G3DSA:3.40.190.10 196 281 1.6E-16 T 06-07-2017 CAL12_RS09885 984af86b3f03479a26d6d8e509ab5081 322 SUPERFAMILY SSF53850 106 316 8.15E-40 T 06-07-2017 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 321 512 1.6E-64 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 Pfam PF02203 Tar ligand binding domain homologue 1 159 1.5E-15 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 SMART SM00304 213 265 1.9E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 SUPERFAMILY SSF47170 25 175 1.96E-13 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 Pfam PF00672 HAMP domain 194 261 1.0E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 SMART SM00283 266 513 4.7E-98 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 Gene3D G3DSA:1.10.287.950 281 485 1.0E-64 T 06-07-2017 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 Gene3D G3DSA:1.20.120.30 42 149 1.2E-6 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11945 a77c06500a2809ca061979b38ce951bf 627 SUPERFAMILY SSF58104 233 514 9.81E-78 T 06-07-2017 CAL12_RS18380 842dedc31da34839fd67a9dcd28e41ff 101 SUPERFAMILY SSF51278 1 101 4.97E-48 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18380 842dedc31da34839fd67a9dcd28e41ff 101 Pfam PF00699 Urease beta subunit 3 100 2.5E-46 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18380 842dedc31da34839fd67a9dcd28e41ff 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.308 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18380 842dedc31da34839fd67a9dcd28e41ff 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 100 2.8E-45 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18380 842dedc31da34839fd67a9dcd28e41ff 101 Gene3D G3DSA:2.10.150.10 1 101 3.0E-51 T 06-07-2017 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 Pfam PF00107 Zinc-binding dehydrogenase 167 300 8.8E-30 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 Gene3D G3DSA:3.90.180.10 3 162 9.0E-46 T 06-07-2017 IPR011032 GroES-like CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 SUPERFAMILY SSF50129 5 156 3.2E-40 T 06-07-2017 IPR011032 GroES-like CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 Gene3D G3DSA:3.40.50.720 163 285 2.2E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 SUPERFAMILY SSF51735 132 310 1.47E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 SMART SM00829 14 336 2.2E-38 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS12980 ac550bfb961e8133c5646aab85915f4c 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 96 1.3E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 SUPERFAMILY SSF51126 192 319 5.02E-5 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 SUPERFAMILY SSF51126 125 160 5.02E-5 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 Gene3D G3DSA:2.160.20.20 2 120 9.4E-13 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 Pfam PF12951 Passenger-associated-transport-repeat 7 36 1.8E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 Pfam PF12951 Passenger-associated-transport-repeat 295 319 9.1E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 6 36 1.6E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 293 320 3.1E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23650 ce24297e3124b3d3f9f660c9e1b98efb 321 SUPERFAMILY SSF51126 1 128 2.61E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23915 0df5ed2c5352ea656504227aa28d4df9 77 Pfam PF02597 ThiS family 1 77 5.0E-17 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAL12_RS23915 0df5ed2c5352ea656504227aa28d4df9 77 Gene3D G3DSA:3.10.20.30 1 77 1.9E-18 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS23915 0df5ed2c5352ea656504227aa28d4df9 77 SUPERFAMILY SSF54285 1 77 1.48E-14 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 Gene3D G3DSA:1.10.10.10 11 81 5.3E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 SMART SM00346 16 103 4.8E-18 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 Pfam PF01614 Bacterial transcriptional regulator 133 256 5.6E-20 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 Pfam PF09339 IclR helix-turn-helix domain 18 64 3.1E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 SUPERFAMILY SSF46785 17 86 1.21E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 Gene3D G3DSA:3.30.450.40 82 265 9.8E-54 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02235 1424377645eba55045f3ee1389df40a9 269 SUPERFAMILY SSF55781 71 261 1.11E-42 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 SMART SM01130 4 296 5.0E-77 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 SUPERFAMILY SSF51569 4 290 4.92E-75 T 06-07-2017 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 3.9E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 3.9E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 3.9E-11 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 PIRSF PIRSF001365 1 297 7.1E-70 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 Gene3D G3DSA:3.20.20.70 3 290 7.8E-81 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS20750 45cdf514086475110ca6eadd89b86821 300 Pfam PF00701 Dihydrodipicolinate synthetase family 6 289 2.3E-49 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 Gene3D G3DSA:3.30.160.20 150 218 9.4E-22 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 Pfam PF00035 Double-stranded RNA binding motif 153 218 5.2E-9 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 SMART SM00535 18 146 9.2E-52 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 218 2.7E-69 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 Pfam PF14622 Ribonuclease-III-like 17 137 8.4E-37 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 29.286 T 06-07-2017 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 SUPERFAMILY SSF54768 106 220 2.99E-22 T 06-07-2017 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 SUPERFAMILY SSF69065 2 144 5.76E-46 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 SMART SM00358 153 221 2.9E-13 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAL12_RS08415 8ca7bfe90e9fbd8d36ac48d3db9fdb9a 252 Gene3D G3DSA:1.10.1520.10 2 143 2.4E-46 T 06-07-2017 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CAL12_RS17025 dc6c7b8ce434039dfa64552d84e65235 128 SUPERFAMILY SSF54427 8 127 1.67E-28 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS17025 dc6c7b8ce434039dfa64552d84e65235 128 Pfam PF12893 Putative lumazine-binding 12 125 1.6E-22 T 06-07-2017 CAL12_RS17025 dc6c7b8ce434039dfa64552d84e65235 128 Gene3D G3DSA:3.10.450.50 6 127 2.2E-30 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 223 238 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 169 182 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 303 323 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 367 383 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 245 273 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PRINTS PR00143 Citrate synthase signature 387 401 4.3E-53 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 PIRSF PIRSF001369 41 434 2.7E-157 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 4.6E-128 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 430 2.1E-231 T 06-07-2017 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 Gene3D G3DSA:1.10.580.10 56 285 9.9E-95 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 SUPERFAMILY SSF48256 9 430 6.93E-157 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19245 92210c0e5ecdac8e8cd431aa4b7b6666 434 Gene3D G3DSA:1.10.230.10 286 380 6.4E-38 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 Pfam PF10135 Rod binding protein 56 102 1.6E-12 T 06-07-2017 IPR019301 Flagellar protein FlgJ, N-terminal CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 SMART SM00047 172 332 3.1E-44 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 SUPERFAMILY SSF53955 168 219 1.12E-5 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 16 324 2.5E-107 T 06-07-2017 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 PRINTS PR01002 Flagellar protein FlgJ signature 195 216 3.0E-6 T 06-07-2017 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 PRINTS PR01002 Flagellar protein FlgJ signature 34 57 3.0E-6 T 06-07-2017 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 PRINTS PR01002 Flagellar protein FlgJ signature 59 79 3.0E-6 T 06-07-2017 CAL12_RS11930 d41e13ce7e84c3ccc7f06786423b4de2 356 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 188 325 7.0E-21 T 06-07-2017 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 Gene3D G3DSA:1.10.10.10 10 84 8.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 Pfam PF07729 FCD domain 93 217 8.6E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 82 8.9E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 SUPERFAMILY SSF48008 89 225 1.83E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 SMART SM00895 92 217 1.4E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 Gene3D G3DSA:1.20.120.530 86 229 2.4E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 SUPERFAMILY SSF46785 17 98 2.94E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10280 e44b74167962fd9ca1d81e9b259338ba 238 SMART SM00345 24 82 1.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 124 1.5E-12 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 SUPERFAMILY SSF51604 112 363 4.85E-58 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 SUPERFAMILY SSF54826 1 126 1.69E-22 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 Pfam PF13378 Enolase C-terminal domain-like 145 358 9.1E-48 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 Gene3D G3DSA:3.20.20.120 128 364 1.6E-55 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 SMART SM00922 142 238 4.2E-17 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS04075 5fb5374da65bf7606c5cae145d1507c5 369 Gene3D G3DSA:3.30.390.10 1 127 3.3E-30 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS05300 2f613cd9d3f492ea51e284f26deb1d11 149 Pfam PF01575 MaoC like domain 15 110 4.0E-15 T 06-07-2017 IPR002539 MaoC-like domain CAL12_RS05300 2f613cd9d3f492ea51e284f26deb1d11 149 SUPERFAMILY SSF54637 2 142 4.02E-32 T 06-07-2017 IPR029069 HotDog domain CAL12_RS05300 2f613cd9d3f492ea51e284f26deb1d11 149 Gene3D G3DSA:3.10.129.10 2 141 6.4E-37 T 06-07-2017 IPR029069 HotDog domain CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 8.2E-134 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 PIRSF PIRSF001456 3 351 1.3E-131 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 Gene3D G3DSA:3.60.150.10 9 351 5.0E-149 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 35.674 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 Pfam PF01264 Chorismate synthase 10 345 7.2E-132 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 SUPERFAMILY SSF103263 4 351 2.22E-142 T 06-07-2017 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS09655 b1911c6e77d20d35e7b76eea46fea6f8 352 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 06-07-2017 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 PRINTS PR00139 Asparaginase/glutaminase family signature 10 21 2.9E-13 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 PRINTS PR00139 Asparaginase/glutaminase family signature 278 296 2.9E-13 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 PRINTS PR00139 Asparaginase/glutaminase family signature 93 111 2.9E-13 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 SMART SM00870 9 336 4.0E-95 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 Gene3D G3DSA:3.40.50.1170 6 207 1.7E-55 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 PIRSF PIRSF001220 4 340 6.9E-72 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 Pfam PF00710 Asparaginase, N-terminal 9 204 1.7E-48 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 PIRSF PIRSF500176 6 341 1.9E-64 T 06-07-2017 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 Gene3D G3DSA:3.40.50.40 231 340 1.3E-27 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CAL12_RS00350 bb9be16d8d92afc48b667efe1be27a1d 342 SUPERFAMILY SSF53774 3 341 1.57E-81 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 SMART SM00866 98 240 3.3E-27 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 SMART SM00345 19 78 5.6E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 Pfam PF07702 UTRA domain 103 239 4.9E-29 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 Gene3D G3DSA:3.40.1410.10 76 241 6.6E-37 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 Gene3D G3DSA:1.10.10.10 13 75 8.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 3.4E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 SUPERFAMILY SSF46785 13 82 7.64E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18590 78683689e60d4dbc81f84a820ec7b0b6 250 SUPERFAMILY SSF64288 68 242 9.26E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS21160 35ad5a49d2a0591971042c47e2236479 504 SUPERFAMILY SSF53850 22 498 4.54E-127 T 06-07-2017 CAL12_RS21160 35ad5a49d2a0591971042c47e2236479 504 Gene3D G3DSA:3.10.105.10 281 473 9.3E-52 T 06-07-2017 CAL12_RS21160 35ad5a49d2a0591971042c47e2236479 504 PIRSF PIRSF002741 9 504 1.5E-101 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS21160 35ad5a49d2a0591971042c47e2236479 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 420 2.3E-80 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS21160 35ad5a49d2a0591971042c47e2236479 504 Gene3D G3DSA:3.40.190.10 125 280 2.0E-41 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 349 355 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 32 716 0.0 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 591 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 492 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 347 361 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 503 513 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 190 204 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 575 6.1E-25 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Pfam PF00702 haloacid dehalogenase-like hydrolase 343 570 8.4E-32 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Gene3D G3DSA:3.40.50.1000 483 603 3.2E-36 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Gene3D G3DSA:2.70.150.10 70 244 8.0E-22 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Pfam PF00122 E1-E2 ATPase 97 338 2.5E-37 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF56784 335 359 1.24E-37 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF56784 394 444 1.24E-37 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF56784 475 599 1.24E-37 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF81653 156 243 9.02E-20 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 33 720 40.333 T 06-07-2017 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 Gene3D G3DSA:3.40.1110.10 358 482 2.5E-45 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 132 369 2.5E-28 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 411 643 3.1E-46 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF81665 244 341 5.23E-12 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF81665 643 699 5.23E-12 T 06-07-2017 CAL12_RS21585 44ac143d3bc9c1aebe1b6796d8681258 722 SUPERFAMILY SSF81665 54 128 5.23E-12 T 06-07-2017 CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 289 2.5E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Gene3D G3DSA:3.40.50.300 343 586 2.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 ProSitePatterns PS00211 ABC transporters family signature. 741 755 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 563 585 1.0E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 SUPERFAMILY SSF52540 610 834 2.22E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 SMART SM00382 634 817 6.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 SMART SM00382 369 563 7.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 SUPERFAMILY SSF52540 344 586 4.44E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Gene3D G3DSA:3.40.50.300 610 834 2.1E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Pfam PF00005 ABC transporter 625 768 3.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01520 25558f3c788c3eda2d74284de6770a79 843 Pfam PF00005 ABC transporter 362 514 4.9E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 237 4.1E-42 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 Gene3D G3DSA:3.40.710.10 251 611 1.4E-104 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 Gene3D G3DSA:3.90.1310.10 129 250 9.1E-36 T 06-07-2017 CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 SUPERFAMILY SSF56601 252 611 2.73E-97 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 SUPERFAMILY SSF56519 54 251 7.59E-48 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 612 2.3E-220 T 06-07-2017 IPR017790 Penicillin-binding protein 2 GO:0016020 CAL12_RS25290 b3007900ec0109120ba18108a7357f10 691 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 607 5.8E-66 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:3.30.2090.10 183 276 1.8E-26 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:3.30.2090.10 731 820 3.5E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82714 731 815 1.2E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82714 184 273 1.96E-21 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:3.30.70.1430 40 136 1.0E-30 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 681 730 4.19E-26 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 817 866 4.19E-26 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 40 131 9.68E-26 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 139 183 4.19E-18 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 276 332 4.19E-18 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Pfam PF00873 AcrB/AcrD/AcrF family 4 1037 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:1.10.3850.10 824 1038 1.5E-59 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1047 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82866 298 498 4.84E-50 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82693 574 680 1.15E-20 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 SUPERFAMILY SSF82866 840 1037 3.53E-45 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:1.20.1640.10 296 505 5.4E-57 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 Gene3D G3DSA:3.30.70.1430 577 680 3.2E-22 T 06-07-2017 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 446 469 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS20550 24d2cead2d94807bed6b151ac812d7c6 1053 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 3.4E-83 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 SUPERFAMILY SSF88659 97 180 2.99E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 SUPERFAMILY SSF88946 3 109 1.44E-24 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 180 5.0E-27 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 Pfam PF04542 Sigma-70 region 2 25 90 1.4E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 Gene3D G3DSA:1.10.1740.10 7 111 4.0E-25 T 06-07-2017 CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 Gene3D G3DSA:1.10.10.10 118 180 6.1E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02155 be27786aa3858865b27ba12f3afc2d75 181 Pfam PF08281 Sigma-70, region 4 124 176 2.1E-13 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS07495 2b7f914ce46122cc3d6126482387a2cc 230 Gene3D G3DSA:1.10.3720.10 22 222 1.7E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07495 2b7f914ce46122cc3d6126482387a2cc 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 116 3.0E-23 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS07495 2b7f914ce46122cc3d6126482387a2cc 230 SUPERFAMILY SSF161098 21 211 7.98E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07495 2b7f914ce46122cc3d6126482387a2cc 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 222 2.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08900 04927cc8bf792004dbca03f95627dd08 326 PIRSF PIRSF017082 1 325 2.0E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08900 04927cc8bf792004dbca03f95627dd08 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 1.9E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08900 04927cc8bf792004dbca03f95627dd08 326 SUPERFAMILY SSF53850 115 289 4.22E-15 T 06-07-2017 CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Gene3D G3DSA:1.10.10.10 12 91 4.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 72 1.4E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 116 173 1.3E-12 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Pfam PF03466 LysR substrate binding domain 198 402 6.1E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Gene3D G3DSA:1.10.10.10 115 197 4.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 SUPERFAMILY SSF46785 12 95 4.81E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Gene3D G3DSA:3.40.190.10 292 372 1.4E-11 T 06-07-2017 CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 SUPERFAMILY SSF53850 200 405 1.05E-34 T 06-07-2017 CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 SUPERFAMILY SSF46785 111 222 9.91E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13730 e070c18f8c67d2af06700c242ad3ed5e 422 Gene3D G3DSA:3.40.190.10 200 291 2.9E-20 T 06-07-2017 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 Gene3D G3DSA:1.10.10.60 179 231 9.5E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 SUPERFAMILY SSF51215 28 161 4.45E-23 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 Pfam PF12833 Helix-turn-helix domain 200 278 2.1E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 Gene3D G3DSA:1.10.10.60 232 278 2.2E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 SMART SM00342 194 276 9.6E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 SUPERFAMILY SSF46689 180 228 1.79E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 SUPERFAMILY SSF46689 230 280 2.42E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 Gene3D G3DSA:2.60.120.280 26 141 6.1E-18 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS16660 10a212758bec8d43220e332a6c04ae1b 284 Pfam PF02311 AraC-like ligand binding domain 24 151 5.8E-24 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 SUPERFAMILY SSF52540 31 324 1.41E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 Pfam PF00005 ABC transporter 23 197 4.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 313 4.4E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 332 3.1E-26 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 SMART SM00382 32 255 1.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS20085 47b799ab45a110d7fac100008f56fc9e 349 Gene3D G3DSA:3.40.50.300 3 271 3.6E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11385 d18e10bc74b265c9dce9266658f380ea 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 2.0E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 SMART SM00450 160 280 1.4E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 SMART SM00450 9 135 4.0E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 ProSitePatterns PS00380 Rhodanese signature 1. 42 53 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 Gene3D G3DSA:3.40.250.10 1 146 6.9E-45 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 Gene3D G3DSA:3.40.250.10 162 286 2.2E-31 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 Pfam PF00581 Rhodanese-like domain 11 131 3.4E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 Pfam PF00581 Rhodanese-like domain 162 275 3.5E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 SUPERFAMILY SSF52821 2 148 1.31E-38 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 ProSitePatterns PS00683 Rhodanese C-terminal signature. 264 274 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAL12_RS14845 4fd483eb654a8e53bc2925e60f2906f6 288 SUPERFAMILY SSF52821 163 286 1.31E-28 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 Pfam PF00005 ABC transporter 17 171 1.4E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 PIRSF PIRSF039085 1 247 1.6E-98 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 SMART SM00382 26 219 8.8E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 SUPERFAMILY SSF52540 1 241 4.66E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21825 ac61c0e0074b751429bfd0221e7af309 256 Gene3D G3DSA:3.40.50.300 1 242 7.1E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 SUPERFAMILY SSF55326 9 171 1.43E-52 T 06-07-2017 CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 63 166 1.8E-14 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 Gene3D G3DSA:3.30.1330.10 24 171 1.6E-62 T 06-07-2017 IPR016188 PurM-like, N-terminal domain CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 342 1.7E-38 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 338 3.4E-134 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 Gene3D G3DSA:3.90.650.10 173 345 4.7E-66 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 347 46.264 T 06-07-2017 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS06390 f424f3c926bd48a61b4b7ed18c7faede 349 SUPERFAMILY SSF56042 173 343 1.26E-57 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 SUPERFAMILY SSF51735 8 168 6.86E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 PIRSF PIRSF000103 1 298 5.0E-71 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 290 2.3E-14 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 Gene3D G3DSA:3.40.50.720 6 169 8.9E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 Gene3D G3DSA:1.10.1040.10 171 293 8.9E-22 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 SUPERFAMILY SSF48179 169 294 1.93E-24 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS19035 9124211770038dd1af3111dc75dd58b3 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 168 2.0E-38 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 337 2.1E-150 T 06-07-2017 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 Gene3D G3DSA:3.90.25.10 192 348 3.2E-55 T 06-07-2017 CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 Gene3D G3DSA:3.40.50.720 1 191 8.0E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 SUPERFAMILY SSF51735 1 349 8.06E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27015 29a0f79df1b9811cb87f21865d236538 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 6.8E-98 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 Pfam PF03466 LysR substrate binding domain 86 288 6.4E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 SUPERFAMILY SSF46785 4 82 9.98E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 Gene3D G3DSA:1.10.10.10 3 83 2.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.0E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 Gene3D G3DSA:3.40.190.10 87 193 7.4E-17 T 06-07-2017 CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 Gene3D G3DSA:3.40.190.10 194 266 9.3E-13 T 06-07-2017 CAL12_RS07865 220563ce0e91fa04b9f8dec5f0fca392 318 SUPERFAMILY SSF53850 86 290 1.21E-32 T 06-07-2017 CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 Gene3D G3DSA:3.40.50.970 11 208 2.6E-36 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 SUPERFAMILY SSF52518 399 581 1.04E-30 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 432 578 1.4E-21 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 Gene3D G3DSA:3.40.50.1220 217 407 7.1E-9 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 194 1.3E-38 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 SUPERFAMILY SSF52467 181 375 2.2E-15 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 SUPERFAMILY SSF52518 11 200 3.2E-32 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 Gene3D G3DSA:3.40.50.970 408 581 4.3E-32 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05820 f84f192576566112f3c46856a9c91063 584 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 455 474 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS22325 74fca6c9cf37815eda3732c042f796e3 215 Pfam PF04752 ChaC-like protein 46 209 3.0E-40 T 06-07-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 CAL12_RS22325 74fca6c9cf37815eda3732c042f796e3 215 SUPERFAMILY SSF110857 46 155 1.44E-10 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS22325 74fca6c9cf37815eda3732c042f796e3 215 Gene3D G3DSA:3.10.490.10 43 202 1.0E-19 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 Gene3D G3DSA:3.40.50.720 2 257 6.7E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 SUPERFAMILY SSF51735 1 258 3.49E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 2.1E-48 T 06-07-2017 CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.2E-27 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02180 767a795022a7ff9ec4f86799bb0f3a10 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23535 7141bc3d90f25bddf4ca1edf77152d80 276 SUPERFAMILY SSF161098 13 266 1.44E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23535 7141bc3d90f25bddf4ca1edf77152d80 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 260 7.5E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23535 7141bc3d90f25bddf4ca1edf77152d80 276 Gene3D G3DSA:1.10.3720.10 20 265 3.5E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 81 270 8.3E-18 T 06-07-2017 IPR001761 Periplasmic binding protein/LacI sugar binding domain CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 SMART SM00354 22 92 2.8E-17 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 Gene3D G3DSA:1.10.260.40 24 74 1.1E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 Gene3D G3DSA:3.40.50.2300 193 321 1.6E-30 T 06-07-2017 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 SUPERFAMILY SSF47413 23 81 3.92E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 SUPERFAMILY SSF53822 80 334 8.99E-47 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 26 69 3.1E-14 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS11600 44bc692c90e8e0e676e3c8305f587d43 344 Gene3D G3DSA:3.40.50.2300 75 192 1.1E-29 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Pfam PF00072 Response regulator receiver domain 569 683 3.1E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SUPERFAMILY SSF55874 364 538 1.24E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:3.40.50.2300 566 676 8.7E-36 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 537 1.3E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SMART SM00062 39 262 1.6E-23 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:3.40.190.10 128 212 6.1E-8 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 259 8.5E-27 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SUPERFAMILY SSF47384 302 376 7.46E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:1.10.287.130 306 371 1.1E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:3.30.565.10 376 539 3.4E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SMART SM00448 567 683 1.7E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SUPERFAMILY SSF47226 666 768 1.06E-9 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:3.40.190.10 37 127 2.0E-17 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:3.40.190.10 222 260 2.0E-17 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 1.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 493 1.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 518 1.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 PRINTS PR00344 Bacterial sensor protein C-terminal signature 524 537 1.3E-15 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SMART SM00387 422 540 4.8E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Gene3D G3DSA:1.20.120.160 677 763 8.3E-7 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SUPERFAMILY SSF53850 33 260 3.55E-35 T 06-07-2017 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SMART SM00388 310 375 1.3E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 Pfam PF00512 His Kinase A (phospho-acceptor) domain 311 375 2.6E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04560 ede924e97a55a70b4ac1232ab97b1575 790 SUPERFAMILY SSF52172 567 688 1.42E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 169 183 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 38 258 6.7E-74 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 29 260 35.816 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 49 64 - T 06-07-2017 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 SUPERFAMILY SSF53335 22 251 5.36E-45 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 Pfam PF01209 ubiE/COQ5 methyltransferase family 34 259 1.3E-80 T 06-07-2017 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CAL12_RS25595 a2a8534d61ab842eaaed5a5f889ecfce 262 Gene3D G3DSA:3.40.50.150 37 258 1.3E-51 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS06790 6c3826d33c69a70df646d7c270b14298 322 SUPERFAMILY SSF51735 1 317 2.63E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06790 6c3826d33c69a70df646d7c270b14298 322 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 5 309 3.5E-62 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS06790 6c3826d33c69a70df646d7c270b14298 322 PIRSF PIRSF001439 1 318 4.3E-72 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS06790 6c3826d33c69a70df646d7c270b14298 322 Gene3D G3DSA:3.40.50.720 131 291 3.5E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06790 6c3826d33c69a70df646d7c270b14298 322 Gene3D G3DSA:3.30.1780.10 1 130 2.1E-32 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS03895 a85aa0c622facdc46fb519fed0e204b5 320 SUPERFAMILY SSF53850 108 283 1.57E-9 T 06-07-2017 CAL12_RS03895 a85aa0c622facdc46fb519fed0e204b5 320 PIRSF PIRSF017082 1 319 2.7E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03895 a85aa0c622facdc46fb519fed0e204b5 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 2.6E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23285 4534956e8a8e7810d1a6c55872bbd8f5 287 Pfam PF04909 Amidohydrolase 23 285 5.6E-35 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23285 4534956e8a8e7810d1a6c55872bbd8f5 287 SUPERFAMILY SSF51556 22 285 1.8E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23285 4534956e8a8e7810d1a6c55872bbd8f5 287 Gene3D G3DSA:3.20.20.140 14 285 1.0E-87 T 06-07-2017 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 315 404 3.2E-19 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 469 43.099 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Pfam PF01225 Mur ligase family, catalytic domain 7 105 2.3E-25 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Pfam PF08245 Mur ligase middle domain 110 294 1.5E-26 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 SUPERFAMILY SSF51984 6 92 4.71E-28 T 06-07-2017 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Gene3D G3DSA:3.40.50.720 6 92 4.4E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 SUPERFAMILY SSF53244 313 458 3.66E-46 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Gene3D G3DSA:3.40.1190.10 94 315 7.7E-81 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 SUPERFAMILY SSF53623 91 312 7.06E-70 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 Gene3D G3DSA:3.90.190.20 316 464 4.8E-53 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22405 ebc6bb3b2d8f5d80c3fe343d82f3d5f8 481 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 461 7.2E-164 T 06-07-2017 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS12295 c4fc9b5780961c77e90454ba2b91aa20 110 SMART SM00530 52 108 0.0052 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS12295 c4fc9b5780961c77e90454ba2b91aa20 110 Pfam PF13744 Helix-turn-helix domain 37 109 1.2E-16 T 06-07-2017 CAL12_RS12295 c4fc9b5780961c77e90454ba2b91aa20 110 SUPERFAMILY SSF47413 42 109 6.65E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS12295 c4fc9b5780961c77e90454ba2b91aa20 110 Gene3D G3DSA:1.10.260.40 41 102 9.3E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 SMART SM00987 55 215 5.9E-28 T 06-07-2017 CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 25 214 1.8E-70 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 Pfam PF03167 Uracil DNA glycosylase superfamily 55 209 7.7E-34 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 SMART SM00986 55 215 5.9E-28 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 Gene3D G3DSA:3.40.470.10 35 214 1.2E-57 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 41 201 1.3E-38 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAL12_RS00205 8db590b37c0fb1e58bd07652ce1e75c0 233 SUPERFAMILY SSF52141 34 212 6.21E-48 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS22980 a72e29308e3b929a4c203ea60eafe11c 392 Gene3D G3DSA:3.40.50.2000 35 190 2.9E-32 T 06-07-2017 CAL12_RS22980 a72e29308e3b929a4c203ea60eafe11c 392 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 107 356 2.3E-31 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS22980 a72e29308e3b929a4c203ea60eafe11c 392 Gene3D G3DSA:3.40.50.2000 209 379 3.0E-51 T 06-07-2017 CAL12_RS22980 a72e29308e3b929a4c203ea60eafe11c 392 SUPERFAMILY SSF53756 34 378 1.1E-78 T 06-07-2017 CAL12_RS11215 d07c0fb766f842668597c9137c3e7ce6 322 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 153 165 - T 06-07-2017 IPR033140 Lipase, GDXG, putative serine active site CAL12_RS11215 d07c0fb766f842668597c9137c3e7ce6 322 Pfam PF07859 alpha/beta hydrolase fold 81 289 2.9E-65 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS11215 d07c0fb766f842668597c9137c3e7ce6 322 Gene3D G3DSA:3.40.50.1820 29 311 2.2E-85 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11215 d07c0fb766f842668597c9137c3e7ce6 322 SUPERFAMILY SSF53474 45 294 1.11E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 SUPERFAMILY SSF53822 56 415 1.68E-95 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 57 415 1.8E-161 T 06-07-2017 IPR017777 ABC transporter, urea, substrate-binding, UrtA CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 Pfam PF13433 Periplasmic binding protein domain 58 417 2.7E-133 T 06-07-2017 CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 Gene3D G3DSA:3.40.50.2300 330 385 1.1E-52 T 06-07-2017 CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 Gene3D G3DSA:3.40.50.2300 53 175 1.1E-52 T 06-07-2017 CAL12_RS03790 f4ad46022978f7bc6157c1b3fa4f10c9 420 Gene3D G3DSA:3.40.50.2300 176 329 4.3E-20 T 06-07-2017 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 Pfam PF03309 Type III pantothenate kinase 157 243 1.6E-23 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 Pfam PF03309 Type III pantothenate kinase 4 144 7.9E-17 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 SUPERFAMILY SSF53067 64 142 7.12E-14 T 06-07-2017 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 SUPERFAMILY SSF53067 4 20 7.12E-14 T 06-07-2017 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 Hamap MF_01274 Type III pantothenate kinase [coaX]. 3 307 15.056 T 06-07-2017 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 SUPERFAMILY SSF53067 165 271 2.04E-21 T 06-07-2017 CAL12_RS26840 fc02907a8fd41ac3b410d93d5cece21d 311 Gene3D G3DSA:3.30.420.40 118 306 9.6E-33 T 06-07-2017 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 Gene3D G3DSA:3.40.190.10 96 181 2.5E-24 T 06-07-2017 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 Pfam PF03466 LysR substrate binding domain 95 296 2.0E-48 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 5.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 5.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 5.5E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 SUPERFAMILY SSF46785 6 117 2.23E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 SUPERFAMILY SSF53850 96 298 3.26E-47 T 06-07-2017 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 Gene3D G3DSA:3.40.190.10 182 267 1.1E-24 T 06-07-2017 CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 Gene3D G3DSA:1.10.10.10 7 91 1.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02570 2784ec29d4730c0dd1f04439441d8354 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 3.7E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24245 9b172d31368c9b18980366088422d823 277 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 67 87 - T 06-07-2017 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 CAL12_RS24245 9b172d31368c9b18980366088422d823 277 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 189 276 6.0E-27 T 06-07-2017 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAL12_RS24245 9b172d31368c9b18980366088422d823 277 SMART SM00849 29 188 1.2E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24245 9b172d31368c9b18980366088422d823 277 Gene3D G3DSA:3.60.15.10 22 277 7.2E-87 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24245 9b172d31368c9b18980366088422d823 277 Pfam PF00753 Metallo-beta-lactamase superfamily 31 188 1.4E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24245 9b172d31368c9b18980366088422d823 277 SUPERFAMILY SSF56281 22 276 1.82E-68 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24245 9b172d31368c9b18980366088422d823 277 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 22 276 2.2E-101 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAL12_RS24245 9b172d31368c9b18980366088422d823 277 PIRSF PIRSF005457 16 276 1.3E-98 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAL12_RS24245 9b172d31368c9b18980366088422d823 277 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 19 276 43.01 T 06-07-2017 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 279 312 9.4E-42 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 427 444 9.4E-42 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 93 130 9.4E-42 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 1327 1458 2.5E-49 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 480 532 9.4E-42 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 1164 1198 2.5E-49 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 1675 1801 3.8E-45 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.20.1580.10 747 877 2.5E-42 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 ProSitePatterns PS00211 ABC transporters family signature. 1811 1825 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SMART SM00382 686 1079 0.23 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SMART SM00382 1613 1900 3.8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SMART SM00382 1092 1545 2.9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 1067 1127 4.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 1459 1580 4.8E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 5 52 4.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 655 745 2.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 1802 1935 1.5E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 878 1008 2.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 533 645 4.1E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.40.50.300 1585 1661 1.5E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 991 1.6E-283 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 ProSitePatterns PS00211 ABC transporters family signature. 1468 1482 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 1596 1907 4.52E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 6 214 9.63E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 480 624 9.63E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 1075 1273 3.09E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 1411 1550 3.09E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:1.10.8.280 314 426 1.6E-25 T 06-07-2017 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.30.1490.20 1269 1303 2.9E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 Gene3D G3DSA:3.30.1490.20 1199 1222 2.9E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS05435 84b3e72ffa4aac209f4cd8992de74d34 1938 SUPERFAMILY SSF52540 673 977 3.49E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 Gene3D G3DSA:1.20.1250.20 38 215 3.8E-33 T 06-07-2017 CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 38 519 1.4E-156 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 Pfam PF07690 Major Facilitator Superfamily 42 434 4.1E-54 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 Gene3D G3DSA:1.20.1250.20 290 450 4.6E-18 T 06-07-2017 CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 Gene3D G3DSA:1.20.1250.20 501 526 4.6E-18 T 06-07-2017 CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 SUPERFAMILY SSF103473 273 444 2.09E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 SUPERFAMILY SSF103473 20 218 2.09E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS17845 be36f4fee77e759221a045d11a2b13e5 537 SUPERFAMILY SSF103473 496 523 2.09E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 Gene3D G3DSA:1.10.10.10 103 186 6.2E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 104 183 4.2E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 105 184 2.1E-27 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 154 160 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 SUPERFAMILY SSF46767 103 185 2.62E-27 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 SUPERFAMILY SSF53155 7 48 1.69E-13 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS01680 5f54fd46864a4237d16b14007b4530df 207 SUPERFAMILY SSF53155 75 109 1.69E-13 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 Gene3D G3DSA:3.40.1410.10 108 257 2.9E-47 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 SUPERFAMILY SSF64288 81 258 9.42E-44 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 SMART SM00866 112 254 8.8E-39 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 91 3.9E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 SMART SM00345 32 91 4.5E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 Gene3D G3DSA:1.10.10.10 26 96 2.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 SUPERFAMILY SSF46785 26 103 2.63E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 Pfam PF07702 UTRA domain 113 254 3.3E-36 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 65 81 5.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19275 6925959e5dec73825e5afcd51066b67f 260 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 65 5.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24005 843e4b15379ce30aa7eebc1427efef8a 311 Gene3D G3DSA:3.40.50.1820 68 289 1.2E-39 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24005 843e4b15379ce30aa7eebc1427efef8a 311 Pfam PF12146 Serine aminopeptidase, S33 86 197 5.1E-16 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAL12_RS24005 843e4b15379ce30aa7eebc1427efef8a 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 126 5.3E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS24005 843e4b15379ce30aa7eebc1427efef8a 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 158 171 5.3E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS24005 843e4b15379ce30aa7eebc1427efef8a 311 SUPERFAMILY SSF53474 10 289 6.73E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS15990 c7c6d5b145e8f813421803c5833e43b3 215 Pfam PF02660 Glycerol-3-phosphate acyltransferase 17 201 9.3E-52 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAL12_RS15990 c7c6d5b145e8f813421803c5833e43b3 215 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 13 210 20.926 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAL12_RS15990 c7c6d5b145e8f813421803c5833e43b3 215 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 11 212 5.9E-61 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAL12_RS15990 c7c6d5b145e8f813421803c5833e43b3 215 SMART SM01207 16 202 1.9E-89 T 06-07-2017 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 Gene3D G3DSA:3.30.70.920 69 143 4.2E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 Pfam PF01037 Lrp/AsnC ligand binding domain 72 139 1.3E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 Pfam PF13404 AsnC-type helix-turn-helix domain 5 45 2.7E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 Gene3D G3DSA:1.10.10.10 2 57 1.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 SMART SM00344 5 111 1.5E-29 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 SUPERFAMILY SSF54909 66 143 1.47E-16 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 SUPERFAMILY SSF46785 4 60 7.33E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS09355 adc006b15327319670af93d8b5bf3a30 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.8E-10 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS20625 fc2e93bc1c0699d535cc1a95984d5185 383 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 14 379 1.7E-123 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAL12_RS20625 fc2e93bc1c0699d535cc1a95984d5185 383 Pfam PF06965 Na+/H+ antiporter 1 13 379 4.6E-139 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAL12_RS20625 fc2e93bc1c0699d535cc1a95984d5185 383 Gene3D G3DSA:1.20.1530.10 10 382 1.0E-136 T 06-07-2017 IPR023171 Na/H antiporter domain CAL12_RS20625 fc2e93bc1c0699d535cc1a95984d5185 383 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 11 383 21.895 T 06-07-2017 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 SUPERFAMILY SSF46689 294 343 7.89E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 Gene3D G3DSA:1.10.10.60 247 295 1.7E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 SUPERFAMILY SSF46689 243 289 1.47E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 SMART SM00342 258 341 2.5E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 287 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 Gene3D G3DSA:1.10.10.60 296 343 3.1E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 Pfam PF12852 Cupin 41 226 3.5E-24 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAL12_RS17030 0b7c49f2c2eae15b931cfca88368c986 345 Pfam PF12833 Helix-turn-helix domain 264 341 7.2E-16 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 SMART SM01192 139 426 3.9E-219 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PIRSF PIRSF001400 1 426 2.9E-188 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 Gene3D G3DSA:3.20.20.120 130 425 3.3E-132 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 ProSitePatterns PS00164 Enolase signature. 335 348 - T 06-07-2017 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 SUPERFAMILY SSF51604 139 427 1.84E-128 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 Gene3D G3DSA:3.30.390.10 4 126 2.3E-53 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 1.2E-130 T 06-07-2017 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 Pfam PF03952 Enolase, N-terminal domain 4 133 6.1E-56 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 161 174 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 335 349 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 37 51 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 312 323 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 107 123 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 PRINTS PR00148 Enolase signature 364 381 3.1E-45 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 1.5E-205 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 SMART SM01193 4 134 8.3E-89 T 06-07-2017 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 SUPERFAMILY SSF54826 4 136 1.28E-53 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08650 d03a234383989250fdff7db490a5b49b 428 Hamap MF_00318 Enolase [eno]. 2 412 44.489 T 06-07-2017 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 ProSitePatterns PS01081 TetR-type HTH domain signature. 8 39 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 SUPERFAMILY SSF46689 2 63 9.23E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 Gene3D G3DSA:1.10.357.10 53 175 1.1E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 42 3.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 SUPERFAMILY SSF48498 62 175 2.38E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16675 5b4a6e44ed59894f25a2db9b0571c3b6 176 Gene3D G3DSA:1.10.10.60 1 48 3.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 3.1E-33 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 3.1E-33 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 3.1E-33 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 3.1E-33 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 Gene3D G3DSA:3.40.50.720 2 124 4.5E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 3.2E-126 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 06-07-2017 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 SMART SM00881 4 103 1.7E-29 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 Pfam PF00549 CoA-ligase 156 271 2.0E-16 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 PIRSF PIRSF001553 1 293 2.5E-115 T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 06-07-2017 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 SUPERFAMILY SSF51735 1 127 1.18E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 SUPERFAMILY SSF52210 128 291 9.03E-52 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 Gene3D G3DSA:3.40.50.261 125 292 1.3E-70 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09505 0ec5af11e41deebbe55afb79ba1f76b8 293 Pfam PF02629 CoA binding domain 6 102 1.5E-23 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 SUPERFAMILY SSF55031 228 341 3.44E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 Gene3D G3DSA:3.30.70.360 239 336 2.2E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 29 422 2.2E-80 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 SUPERFAMILY SSF53187 22 233 7.07E-67 T 06-07-2017 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 SUPERFAMILY SSF53187 352 425 7.07E-67 T 06-07-2017 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 Pfam PF01546 Peptidase family M20/M25/M40 83 422 7.6E-27 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 Pfam PF07687 Peptidase dimerisation domain 223 327 1.4E-4 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 Gene3D G3DSA:3.40.630.10 18 238 3.4E-76 T 06-07-2017 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 Gene3D G3DSA:3.40.630.10 367 425 3.4E-76 T 06-07-2017 CAL12_RS10495 e6f2269792aadee0f89a9eb2f3a8e295 428 PIRSF PIRSF001235 9 428 1.1E-109 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 SUPERFAMILY SSF53850 92 294 5.58E-43 T 06-07-2017 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 SUPERFAMILY SSF46785 7 87 2.62E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 Gene3D G3DSA:1.10.10.10 6 86 1.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 Gene3D G3DSA:3.40.190.10 168 265 2.7E-21 T 06-07-2017 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 Gene3D G3DSA:3.40.190.10 93 167 1.3E-4 T 06-07-2017 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.8E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16120 aa07d72cdefbefb25f6d94a0923708ea 304 Pfam PF03466 LysR substrate binding domain 91 294 1.4E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03035 829c10bbbc97196421b9152c093ec57d 287 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 277 1.8E-71 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03035 829c10bbbc97196421b9152c093ec57d 287 Gene3D G3DSA:3.90.850.10 68 278 2.9E-88 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03035 829c10bbbc97196421b9152c093ec57d 287 SUPERFAMILY SSF56529 60 279 5.49E-84 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS12995 9640fc81e9399135e26c51a47d542eb0 247 SMART SM00382 30 213 5.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12995 9640fc81e9399135e26c51a47d542eb0 247 Pfam PF00005 ABC transporter 21 162 5.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12995 9640fc81e9399135e26c51a47d542eb0 247 Gene3D G3DSA:3.40.50.300 3 234 6.3E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12995 9640fc81e9399135e26c51a47d542eb0 247 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12995 9640fc81e9399135e26c51a47d542eb0 247 SUPERFAMILY SSF52540 6 239 1.06E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14740 145c522cedf9341c6a08840dc24a9206 163 Gene3D G3DSA:3.30.1330.40 13 162 1.6E-57 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS14740 145c522cedf9341c6a08840dc24a9206 163 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 15 162 9.2E-31 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS14740 145c522cedf9341c6a08840dc24a9206 163 SUPERFAMILY SSF55298 13 162 3.93E-48 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 113 126 - T 06-07-2017 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 SMART SM00839 196 426 1.4E-99 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 SUPERFAMILY SSF51735 194 428 5.34E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 176 3.3E-55 T 06-07-2017 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 SUPERFAMILY SSF53223 9 196 6.08E-69 T 06-07-2017 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 194 426 4.0E-74 T 06-07-2017 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 PIRSF PIRSF000185 23 429 2.3E-159 T 06-07-2017 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 185 207 1.1E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 1.1E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 227 247 1.1E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 105 119 1.1E-31 T 06-07-2017 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-70614 CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 Gene3D G3DSA:3.40.50.720 194 428 2.8E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15690 c74b7dda23cee4e1609a75759694f91b 429 Gene3D G3DSA:3.40.192.10 52 192 4.7E-58 T 06-07-2017 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Gene3D G3DSA:1.10.8.60 333 398 2.0E-29 T 06-07-2017 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 1.5E-45 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Pfam PF06480 FtsH Extracellular 10 82 1.8E-6 T 06-07-2017 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 599 37.392 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 06-07-2017 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Gene3D G3DSA:3.40.50.300 147 332 3.0E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 SUPERFAMILY SSF52540 146 393 3.72E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 593 6.4E-239 T 06-07-2017 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 Pfam PF01434 Peptidase family M41 384 592 8.0E-79 T 06-07-2017 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 SMART SM00382 186 325 1.5E-25 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS06550 627c441416b1cb5b7dee6ea313653481 629 SUPERFAMILY SSF140990 404 602 1.57E-73 T 06-07-2017 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 75 86 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 65 75 3.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 Gene3D G3DSA:3.40.190.10 213 300 4.1E-25 T 06-07-2017 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 SUPERFAMILY SSF46785 36 146 6.87E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 39 98 5.6E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 Pfam PF03466 LysR substrate binding domain 124 326 8.5E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 Gene3D G3DSA:3.40.190.10 124 212 3.2E-24 T 06-07-2017 CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 Gene3D G3DSA:1.10.10.10 37 121 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00135 59d71a455703416ef486130f56eb66fd 335 SUPERFAMILY SSF53850 127 333 5.43E-33 T 06-07-2017 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 Gene3D G3DSA:1.10.10.10 21 105 2.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 SUPERFAMILY SSF53850 109 314 1.7E-35 T 06-07-2017 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 SUPERFAMILY SSF46785 21 104 5.89E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 Pfam PF03466 LysR substrate binding domain 109 310 4.8E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 Gene3D G3DSA:3.40.190.10 113 197 2.1E-23 T 06-07-2017 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 85 2.4E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 Gene3D G3DSA:3.40.190.10 198 280 2.4E-21 T 06-07-2017 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 73 2.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13305 90ee507242a0358d5b13e718becc259b 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 62 2.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 5 256 5.0E-112 T 06-07-2017 IPR012700 Phosphonate C-P lyase system, PhnK CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 SMART SM00382 31 229 2.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 Gene3D G3DSA:3.40.50.300 3 254 4.0E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 SUPERFAMILY SSF52540 4 254 2.66E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 Pfam PF00005 ABC transporter 23 180 1.2E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05160 377af036f6db80ea640148094797aaa2 258 PIRSF PIRSF037116 1 258 1.4E-134 T 06-07-2017 IPR012700 Phosphonate C-P lyase system, PhnK CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 59 2.7E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 Gene3D G3DSA:3.10.20.30 2 73 2.6E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 Gene3D G3DSA:1.10.150.120 74 154 1.3E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 Pfam PF01799 [2Fe-2S] binding domain 72 144 5.6E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 SUPERFAMILY SSF47741 83 153 2.22E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21725 0e23b5d561fd90f698a07df6bf988741 169 SUPERFAMILY SSF54292 2 77 6.29E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 350 2.1E-127 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 354 47.954 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 Gene3D G3DSA:3.40.718.10 2 352 6.0E-117 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 SUPERFAMILY SSF53659 2 351 1.31E-112 T 06-07-2017 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 SMART SM01329 2 350 6.0E-179 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 349 1.1E-139 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAL12_RS25395 951696c4cffde233d9882304f341c60b 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 241 260 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 415 1.3E-125 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 158 2.3E-45 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 SUPERFAMILY SSF69742 5 160 1.83E-42 T 06-07-2017 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 306 4.7E-44 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 417 28.893 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 SUPERFAMILY SSF51735 165 316 9.47E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 417 2.2E-27 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 06-07-2017 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 PIRSF PIRSF000445 3 424 1.4E-144 T 06-07-2017 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 SUPERFAMILY SSF69075 320 418 5.62E-25 T 06-07-2017 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CAL12_RS25890 7be84afcab895c0922669dee1e179c90 424 Gene3D G3DSA:3.40.50.720 165 312 3.2E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 Gene3D G3DSA:3.30.1130.10 53 181 1.3E-61 T 06-07-2017 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 181 36.467 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 SUPERFAMILY SSF55620 3 181 5.26E-77 T 06-07-2017 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 60 76 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 Pfam PF01227 GTP cyclohydrolase I 4 180 2.5E-74 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 108 118 - T 06-07-2017 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 Gene3D G3DSA:1.10.286.10 3 50 4.1E-21 T 06-07-2017 CAL12_RS09015 6f0af58051df5573a3b5276eb9dbbae2 181 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 4 181 4.5E-74 T 06-07-2017 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 71.102 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 SUPERFAMILY SSF52304 4 143 5.23E-60 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 Gene3D G3DSA:3.40.50.9100 2 144 1.9E-63 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 142 6.0E-59 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 Pfam PF01220 Dehydroquinase class II 4 141 1.1E-57 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 PIRSF PIRSF001399 1 144 6.4E-57 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 143 9.5E-58 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS24875 24c73c1569645469f8a24c2e6df90e2a 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 06-07-2017 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 Gene3D G3DSA:3.40.190.10 87 184 3.1E-17 T 06-07-2017 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 SUPERFAMILY SSF46785 1 82 1.72E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 Gene3D G3DSA:3.40.190.10 185 250 2.2E-16 T 06-07-2017 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 Gene3D G3DSA:1.10.10.10 1 80 4.2E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 SUPERFAMILY SSF53850 87 298 1.12E-31 T 06-07-2017 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.4E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14280 1aed0edff2ec4aff6b7cbb910eff729a 313 Pfam PF03466 LysR substrate binding domain 86 283 4.3E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 SUPERFAMILY SSF54373 270 360 5.89E-19 T 06-07-2017 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.30.9.10 270 359 2.5E-16 T 06-07-2017 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.30.9.10 136 189 2.5E-16 T 06-07-2017 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.50.50.60 360 416 7.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.50.50.60 190 269 7.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.50.50.60 108 122 7.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Gene3D G3DSA:3.50.50.60 1 55 7.3E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 50.171 T 06-07-2017 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 Pfam PF01266 FAD dependent oxidoreductase 2 398 4.5E-69 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 SUPERFAMILY SSF51905 1 54 1.55E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 SUPERFAMILY SSF51905 360 416 1.55E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10655 c361d6b792e9d95bf75edc9f8fde884b 418 SUPERFAMILY SSF51905 107 270 1.55E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 Gene3D G3DSA:3.90.76.10 35 187 9.2E-41 T 06-07-2017 CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 Gene3D G3DSA:3.10.105.10 298 486 5.4E-38 T 06-07-2017 CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 436 6.4E-91 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 PIRSF PIRSF002741 1 514 2.1E-96 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 SUPERFAMILY SSF53850 21 513 1.81E-119 T 06-07-2017 CAL12_RS03090 9c800b4621543eeb9f2ef18ad9d56ad5 516 Gene3D G3DSA:3.40.190.10 188 297 3.2E-34 T 06-07-2017 CAL12_RS03845 1fe117cffe4122e86099ab9ddf526324 343 SUPERFAMILY SSF53850 130 307 5.97E-6 T 06-07-2017 CAL12_RS03845 1fe117cffe4122e86099ab9ddf526324 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 338 2.1E-58 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03845 1fe117cffe4122e86099ab9ddf526324 343 PIRSF PIRSF017082 8 342 9.8E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 SMART SM00244 22 180 3.9E-54 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 Pfam PF16200 C-terminal region of band_7 246 306 9.4E-28 T 06-07-2017 IPR032435 Band 7, C-terminal extension CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 Pfam PF01145 SPFH domain / Band 7 family 26 195 3.3E-29 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 SUPERFAMILY SSF117892 53 187 8.5E-40 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 156 174 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 175 196 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 77 98 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 29 51 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 132 155 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS12220 9bf4503db1ffa1d7c537c15ed6dbcccf 307 PRINTS PR00721 Stomatin signature 112 129 1.7E-31 T 06-07-2017 IPR001972 Stomatin family GO:0016020 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 802 0.0 T 06-07-2017 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 Gene3D G3DSA:3.40.50.2000 474 788 4.2E-134 T 06-07-2017 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 PIRSF PIRSF000460 1 813 2.8E-232 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 SUPERFAMILY SSF53756 3 808 0.0 T 06-07-2017 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 648 660 - T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 Pfam PF00343 Carbohydrate phosphorylase 91 802 0.0 T 06-07-2017 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAL12_RS01965 a52f0a3131bff4886db2c643ad159b96 814 Gene3D G3DSA:3.40.50.2000 3 473 1.1E-203 T 06-07-2017 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 381 395 0.029 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 466 482 0.0033 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 483 500 5.2E-4 T 06-07-2017 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 SUPERFAMILY SSF53300 14 182 3.34E-16 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 516 605 3.7E-17 T 06-07-2017 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Gene3D G3DSA:2.150.10.10 455 595 2.3E-17 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Gene3D G3DSA:2.150.10.10 347 403 2.3E-17 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 SUPERFAMILY SSF51120 366 588 6.41E-19 T 06-07-2017 IPR011049 Serralysin-like metalloprotease, C-terminal CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 480 498 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 PRINTS PR00313 NodO calcium binding signature 385 396 4.2E-13 T 06-07-2017 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 PRINTS PR00313 NodO calcium binding signature 484 492 4.2E-13 T 06-07-2017 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 PRINTS PR00313 NodO calcium binding signature 493 502 4.2E-13 T 06-07-2017 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 PRINTS PR00313 NodO calcium binding signature 466 474 4.2E-13 T 06-07-2017 CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Pfam PF13519 von Willebrand factor type A domain 10 117 4.5E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 SMART SM00327 5 197 1.1E-4 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 471 489 - T 06-07-2017 IPR018511 Hemolysin-type calcium-binding conserved site CAL12_RS11430 ced915834c94f1a1fb067a0815e0a8c7 609 Gene3D G3DSA:3.40.50.410 14 174 4.4E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS23865 2cfa62ece3565232f1076706059b6f0b 321 Gene3D G3DSA:3.10.129.10 216 313 7.1E-14 T 06-07-2017 IPR029069 HotDog domain CAL12_RS23865 2cfa62ece3565232f1076706059b6f0b 321 SUPERFAMILY SSF54637 58 152 9.06E-6 T 06-07-2017 IPR029069 HotDog domain CAL12_RS23865 2cfa62ece3565232f1076706059b6f0b 321 SUPERFAMILY SSF54637 217 317 1.39E-12 T 06-07-2017 IPR029069 HotDog domain CAL12_RS23865 2cfa62ece3565232f1076706059b6f0b 321 Pfam PF03061 Thioesterase superfamily 238 305 1.2E-4 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS23865 2cfa62ece3565232f1076706059b6f0b 321 Gene3D G3DSA:3.10.129.10 39 153 9.0E-4 T 06-07-2017 IPR029069 HotDog domain CAL12_RS14985 160110d0f53f72bc1d7fe19fec38e74d 826 Gene3D G3DSA:1.20.1250.20 434 609 1.5E-17 T 06-07-2017 CAL12_RS14985 160110d0f53f72bc1d7fe19fec38e74d 826 SUPERFAMILY SSF103473 434 821 2.88E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS14985 160110d0f53f72bc1d7fe19fec38e74d 826 Pfam PF07690 Major Facilitator Superfamily 437 756 2.8E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS14985 160110d0f53f72bc1d7fe19fec38e74d 826 Gene3D G3DSA:1.20.1250.20 649 821 1.3E-12 T 06-07-2017 CAL12_RS04495 df0c4766cc0e2cd333973661dbd60f8f 186 Gene3D G3DSA:3.10.180.10 1 147 1.1E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS04495 df0c4766cc0e2cd333973661dbd60f8f 186 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 139 2.2E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS04495 df0c4766cc0e2cd333973661dbd60f8f 186 SUPERFAMILY SSF54593 1 141 3.24E-17 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS25180 cbb778ca24aaf7a04510e268e19d7a46 330 Gene3D G3DSA:3.40.190.10 132 254 4.0E-5 T 06-07-2017 CAL12_RS25180 cbb778ca24aaf7a04510e268e19d7a46 330 SUPERFAMILY SSF53850 117 290 3.35E-15 T 06-07-2017 CAL12_RS25180 cbb778ca24aaf7a04510e268e19d7a46 330 PIRSF PIRSF017082 1 330 5.9E-91 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25180 cbb778ca24aaf7a04510e268e19d7a46 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 3.3E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 Gene3D G3DSA:3.40.50.720 5 218 2.1E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 Pfam PF00106 short chain dehydrogenase 5 192 6.6E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 SUPERFAMILY SSF51735 5 243 5.88E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26980 996f2218fb1edfa7dcde8e881a141e53 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 1.6E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 Gene3D G3DSA:3.40.1060.10 187 301 1.5E-32 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 140 153 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 364 375 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 420 433 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 230 243 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 129 137 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 154 169 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 216 229 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 PRINTS PR00415 Aconitase family signature 307 321 7.2E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 Pfam PF00330 Aconitase family (aconitate hydratase) 28 478 1.1E-137 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 ProSitePatterns PS00450 Aconitase family signature 1. 360 376 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 SUPERFAMILY SSF53732 19 485 5.62E-149 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 23 484 2.6E-185 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 Gene3D G3DSA:3.30.499.10 351 485 1.1E-54 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07730 57408056eab03678c2a9082a745f91ca 489 Gene3D G3DSA:3.30.499.10 22 184 1.3E-23 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 SUPERFAMILY SSF52540 5 247 2.01E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 Pfam PF00005 ABC transporter 21 177 2.1E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 Gene3D G3DSA:3.40.50.300 4 248 4.9E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 SMART SM00382 30 225 7.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01235 f818423396d2c2e8a128f4084c17faac 254 PIRSF PIRSF039085 2 253 1.9E-113 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS07740 68da14791075988cb2b88011c9d74a27 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 250 9.8E-49 T 06-07-2017 CAL12_RS07740 68da14791075988cb2b88011c9d74a27 294 SUPERFAMILY SSF51621 5 256 2.04E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS07740 68da14791075988cb2b88011c9d74a27 294 Gene3D G3DSA:3.20.20.60 5 258 3.2E-60 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 SUPERFAMILY SSF55781 68 332 3.73E-60 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 PIRSF PIRSF005485 1 334 2.5E-105 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 323 25.827 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 Gene3D G3DSA:3.30.450.40 170 332 1.0E-39 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 SUPERFAMILY SSF46785 1 79 5.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 Gene3D G3DSA:1.10.10.10 1 80 1.2E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 Pfam PF01628 HrcA protein C terminal domain 101 316 1.1E-56 T 06-07-2017 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 69 4.0E-6 T 06-07-2017 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 CAL12_RS06220 336744b6552a0db563a9147759e820fc 334 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 329 1.8E-90 T 06-07-2017 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 TIGRFAM TIGR01224 hutI: imidazolonepropionase 32 411 8.0E-140 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 SUPERFAMILY SSF51556 75 375 2.16E-86 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 SUPERFAMILY SSF51338 5 76 3.89E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 SUPERFAMILY SSF51338 374 411 3.89E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 Pfam PF01979 Amidohydrolase family 72 387 2.3E-15 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 Gene3D G3DSA:2.30.40.10 362 412 9.5E-4 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 Gene3D G3DSA:3.20.20.140 87 361 7.2E-41 T 06-07-2017 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 Gene3D G3DSA:2.30.40.10 8 86 1.1E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS16060 600fb0f136bdcf1e3c8aa0ed9fc98e95 416 Hamap MF_00372 Imidazolonepropionase [hutI]. 8 414 41.363 T 06-07-2017 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS27545 c2866dc2641c555bb60da1644321da0a 121 Gene3D G3DSA:3.30.420.100 23 121 6.0E-36 T 06-07-2017 CAL12_RS27545 c2866dc2641c555bb60da1644321da0a 121 SUPERFAMILY SSF53137 3 119 1.26E-48 T 06-07-2017 CAL12_RS27545 c2866dc2641c555bb60da1644321da0a 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 121 25.903 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27545 c2866dc2641c555bb60da1644321da0a 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 121 1.8E-34 T 06-07-2017 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27545 c2866dc2641c555bb60da1644321da0a 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 121 4.2E-36 T 06-07-2017 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 SUPERFAMILY SSF55920 180 445 6.15E-85 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 353 365 - T 06-07-2017 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 Gene3D G3DSA:3.40.350.10 9 183 2.5E-46 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 Pfam PF05195 Aminopeptidase P, N-terminal domain 11 126 3.9E-33 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 SMART SM01011 6 141 1.2E-52 T 06-07-2017 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 SUPERFAMILY SSF53092 7 179 7.06E-46 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 Gene3D G3DSA:3.90.230.10 184 445 6.6E-83 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS05650 876beba1c720bfac2cd0ed52e715c217 447 Pfam PF00557 Metallopeptidase family M24 186 424 9.4E-63 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS14735 7397802a911fc33a901cd440d16a0b72 372 Gene3D G3DSA:3.40.830.10 7 270 2.7E-53 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS14735 7397802a911fc33a901cd440d16a0b72 372 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 12 245 1.3E-24 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS14735 7397802a911fc33a901cd440d16a0b72 372 SUPERFAMILY SSF53213 7 270 9.29E-46 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF46915 239 326 8.63E-16 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF00013 KH domain 562 618 6.4E-11 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 PIRSF PIRSF005499 1 721 5.0E-298 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.361 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SMART SM00316 625 695 1.1E-22 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF03725 3' exoribonuclease family, domain 2 147 208 1.7E-12 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF03725 3' exoribonuclease family, domain 2 466 533 1.2E-4 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF55666 145 235 3.51E-30 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF50249 618 695 1.04E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF54211 2 144 1.27E-52 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF00575 S1 RNA binding domain 624 695 1.1E-17 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Gene3D G3DSA:2.40.50.140 623 696 1.7E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SMART SM00322 557 622 2.5E-13 T 06-07-2017 IPR004087 K Homology domain GO:0003676 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF54211 300 493 2.13E-49 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Gene3D G3DSA:3.30.1370.10 557 622 5.7E-26 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 3.1E-21 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 1.3E-24 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 7.6E-18 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 06-07-2017 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF55666 458 565 8.27E-28 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 SUPERFAMILY SSF54791 560 644 1.67E-22 T 06-07-2017 IPR004088 K Homology domain, type 1 GO:0003723 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Gene3D G3DSA:1.10.10.400 226 319 4.7E-19 T 06-07-2017 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Gene3D G3DSA:3.30.230.70 320 547 6.3E-90 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS20910 563c96f4dcc9e6cba697838812f2cf09 721 Gene3D G3DSA:3.30.230.70 3 224 6.7E-87 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 Gene3D G3DSA:3.40.630.10 172 502 1.4E-137 T 06-07-2017 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 142 1.3E-19 T 06-07-2017 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 SUPERFAMILY SSF53187 179 501 9.73E-122 T 06-07-2017 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 356 363 - T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 Gene3D G3DSA:3.40.220.10 2 159 3.0E-34 T 06-07-2017 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 PRINTS PR00481 Cytosol aminopeptidase signature 352 372 7.4E-56 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 PRINTS PR00481 Cytosol aminopeptidase signature 293 314 7.4E-56 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 PRINTS PR00481 Cytosol aminopeptidase signature 271 288 7.4E-56 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 PRINTS PR00481 Cytosol aminopeptidase signature 380 395 7.4E-56 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 PRINTS PR00481 Cytosol aminopeptidase signature 330 351 7.4E-56 T 06-07-2017 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 495 4.7E-121 T 06-07-2017 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 503 35.99 T 06-07-2017 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CAL12_RS08455 ca364a67a5516b0be9183ecbd088bdbf 503 SUPERFAMILY SSF52949 7 184 5.24E-29 T 06-07-2017 CAL12_RS24240 0c9507fb48e07d899ba8085f42cdfdbc 253 SUPERFAMILY SSF53335 83 190 3.1E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24240 0c9507fb48e07d899ba8085f42cdfdbc 253 Gene3D G3DSA:3.40.50.150 84 210 6.1E-14 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24240 0c9507fb48e07d899ba8085f42cdfdbc 253 Pfam PF08241 Methyltransferase domain 81 130 1.2E-7 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAL12_RS01640 f0b1d1a570734b8675369ed8ea9d1ae3 280 SUPERFAMILY SSF161098 18 266 1.5E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01640 f0b1d1a570734b8675369ed8ea9d1ae3 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 272 1.8E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01640 f0b1d1a570734b8675369ed8ea9d1ae3 280 Gene3D G3DSA:1.10.3720.10 22 271 7.0E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01640 f0b1d1a570734b8675369ed8ea9d1ae3 280 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 11 270 4.7E-104 T 06-07-2017 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 CAL12_RS01640 f0b1d1a570734b8675369ed8ea9d1ae3 280 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 11 270 1.8E-94 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 SUPERFAMILY SSF48498 79 185 1.25E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.5E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.0E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 SUPERFAMILY SSF46689 9 84 1.99E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16720 3384abd48c31156db487dd7644411a23 191 Gene3D G3DSA:1.10.357.10 10 181 5.7E-32 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS04440 3dde27764e4eec76f83dfdb43c1878b0 260 Gene3D G3DSA:3.60.15.10 3 239 3.7E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS04440 3dde27764e4eec76f83dfdb43c1878b0 260 Pfam PF12706 Beta-lactamase superfamily domain 24 218 6.4E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS04440 3dde27764e4eec76f83dfdb43c1878b0 260 SUPERFAMILY SSF56281 7 242 7.15E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 SUPERFAMILY SSF53850 89 286 4.65E-35 T 06-07-2017 CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 Gene3D G3DSA:3.40.190.10 168 248 8.0E-11 T 06-07-2017 CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 Pfam PF03466 LysR substrate binding domain 88 282 5.3E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 Gene3D G3DSA:3.40.190.10 91 167 9.5E-14 T 06-07-2017 CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.9E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 SUPERFAMILY SSF46785 1 106 6.95E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16550 7ad79a7b4050c15da940810b2550c3dc 293 Gene3D G3DSA:1.10.10.10 1 84 3.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19040 d14297226a103d5a75d10a9900df0e1f 277 SUPERFAMILY SSF47240 81 243 1.33E-16 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS19040 d14297226a103d5a75d10a9900df0e1f 277 PIRSF PIRSF012318 9 275 6.2E-91 T 06-07-2017 IPR011197 Uncharacterised conserved protein UCP012318 CAL12_RS19040 d14297226a103d5a75d10a9900df0e1f 277 Pfam PF04305 Protein of unknown function (DUF455) 29 264 3.7E-89 T 06-07-2017 IPR007402 Protein of unknown function DUF455 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 Pfam PF00255 Glutathione peroxidase 6 111 1.4E-43 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 SUPERFAMILY SSF52833 4 157 1.46E-58 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 PIRSF PIRSF000303 1 161 7.4E-62 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.8E-19 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.8E-19 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 PRINTS PR01011 Glutathione peroxidase family signature 123 132 1.8E-19 T 06-07-2017 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 Gene3D G3DSA:3.40.30.10 3 159 2.2E-67 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15595 7ff2bde71de1f09c7909ea4fa4340cb6 161 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 06-07-2017 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 Pfam PF14497 Glutathione S-transferase, C-terminal domain 124 194 1.9E-7 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 SUPERFAMILY SSF47616 80 209 5.43E-32 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 79 5.7E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 210 3.6E-82 T 06-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 Gene3D G3DSA:1.20.1050.10 89 209 1.4E-51 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 Gene3D G3DSA:3.40.30.10 1 88 3.4E-28 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25210 754a10881c771b60049039e57b70bf15 212 SUPERFAMILY SSF52833 1 89 2.72E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 Gene3D G3DSA:2.40.30.10 4 97 1.9E-30 T 06-07-2017 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 2.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 2.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 2.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 2.1E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 Gene3D G3DSA:3.40.50.80 98 257 4.1E-46 T 06-07-2017 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 SUPERFAMILY SSF52343 102 256 9.95E-41 T 06-07-2017 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 228 4.7E-8 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 SUPERFAMILY SSF63380 6 99 4.48E-25 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS15255 53db6d5e6c5b6a546c7e372f917c4c84 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 98 4.0E-9 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS01995 391d15f670c8f89c84508e9367b989de 437 Pfam PF04932 O-Antigen ligase 197 352 7.1E-19 T 06-07-2017 IPR007016 O-antigen ligase-related CAL12_RS26990 cfb662afa48ff0126e786e9d491d7af5 476 Gene3D G3DSA:3.40.50.1000 65 139 1.2E-5 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26990 cfb662afa48ff0126e786e9d491d7af5 476 Gene3D G3DSA:3.40.50.1000 6 18 1.2E-5 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26990 cfb662afa48ff0126e786e9d491d7af5 476 Pfam PF01040 UbiA prenyltransferase family 206 455 2.7E-21 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAL12_RS26990 cfb662afa48ff0126e786e9d491d7af5 476 SUPERFAMILY SSF56784 6 19 7.6E-10 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26990 cfb662afa48ff0126e786e9d491d7af5 476 SUPERFAMILY SSF56784 59 153 7.6E-10 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS10790 eb2bec7749b09a52ae2ffd63b7076393 151 Gene3D G3DSA:3.30.10.10 95 144 2.7E-4 T 06-07-2017 CAL12_RS10790 eb2bec7749b09a52ae2ffd63b7076393 151 Pfam PF11720 Peptidase inhibitor I78 family 87 151 5.4E-24 T 06-07-2017 IPR021719 Proteinase inhibitor I78 CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 Gene3D G3DSA:3.40.190.10 278 335 1.6E-28 T 06-07-2017 CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 Gene3D G3DSA:3.40.190.10 12 126 1.6E-28 T 06-07-2017 CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 Gene3D G3DSA:3.40.190.10 136 277 8.9E-51 T 06-07-2017 CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 PIRSF PIRSF002825 5 347 5.1E-82 T 06-07-2017 IPR026045 Ferric binding protein CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 Pfam PF13343 Bacterial extracellular solute-binding protein 79 311 5.9E-18 T 06-07-2017 CAL12_RS15275 ee5cb7f3e867124d688f701ef4b339e2 347 SUPERFAMILY SSF53850 29 344 1.59E-71 T 06-07-2017 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 Gene3D G3DSA:1.10.3720.10 292 535 3.2E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 Gene3D G3DSA:1.10.3720.10 6 260 5.0E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 SUPERFAMILY SSF161098 278 529 2.75E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 350 530 2.4E-7 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 63 260 2.7E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15280 c7353ea98557b5ccec02d1a92c171d34 555 SUPERFAMILY SSF161098 5 263 9.27E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 6.6E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 Gene3D G3DSA:1.10.10.10 124 219 1.7E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 SMART SM00862 145 218 6.9E-14 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 SMART SM00448 1 112 7.4E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 SUPERFAMILY SSF52172 1 175 1.57E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 Gene3D G3DSA:3.40.50.2300 1 123 5.7E-35 T 06-07-2017 CAL12_RS22605 3e520bfcbd06952404005a2cb260ea83 230 Pfam PF00072 Response regulator receiver domain 3 112 3.9E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Pfam PF07969 Amidohydrolase family 50 248 4.5E-19 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Pfam PF07969 Amidohydrolase family 347 457 3.1E-13 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Gene3D G3DSA:2.30.40.10 401 477 4.5E-9 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Gene3D G3DSA:2.30.40.10 5 65 1.4E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Gene3D G3DSA:3.30.1490.130 284 339 1.9E-25 T 06-07-2017 IPR023100 D-aminoacylase, insert domain GO:0016811 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 SUPERFAMILY SSF51338 5 58 8.78E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 SUPERFAMILY SSF51338 415 474 8.78E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Gene3D G3DSA:3.20.20.140 340 400 3.3E-106 T 06-07-2017 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 Gene3D G3DSA:3.20.20.140 66 281 3.3E-106 T 06-07-2017 CAL12_RS24070 c8df769a4af90558384901f0bb22afdc 484 SUPERFAMILY SSF51556 59 415 1.21E-80 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 Gene3D G3DSA:3.90.1150.10 254 374 4.4E-50 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 Pfam PF00266 Aminotransferase class-V 6 366 1.8E-88 T 06-07-2017 IPR000192 Aminotransferase class V domain CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 Gene3D G3DSA:3.40.640.10 18 253 1.5E-97 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 SUPERFAMILY SSF53383 5 389 4.3E-112 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 4 403 2.9E-226 T 06-07-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 PIRSF PIRSF005572 3 383 1.7E-134 T 06-07-2017 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CAL12_RS17175 e7ce49b65630b14970b81001f4372fc9 403 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 54.543 T 06-07-2017 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 CAL12_RS27325 cd2011fe3d46b5d68e510ab27b6084aa 242 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 48 68 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27325 cd2011fe3d46b5d68e510ab27b6084aa 242 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 47 68 2.7E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27325 cd2011fe3d46b5d68e510ab27b6084aa 242 SUPERFAMILY SSF54523 50 108 4.87E-5 T 06-07-2017 CAL12_RS27325 cd2011fe3d46b5d68e510ab27b6084aa 242 Pfam PF13633 Prokaryotic N-terminal methylation site 47 72 3.2E-10 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Pfam PF03144 Elongation factor Tu domain 2 329 396 3.1E-18 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SMART SM00889 485 604 4.3E-74 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 TIGRFAM TIGR00484 EF-G: translation elongation factor G 3 699 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF54980 609 696 8.15E-31 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SMART SM00838 606 695 2.5E-55 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF52540 6 288 9.12E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Gene3D G3DSA:3.40.50.300 6 293 3.0E-103 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF54211 484 605 3.54E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 1.1E-66 T 06-07-2017 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Pfam PF14492 Elongation Factor G, domain II 409 483 3.3E-35 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Gene3D G3DSA:3.30.70.240 603 696 8.5E-34 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF54980 409 486 6.83E-26 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.5E-31 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.7E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Gene3D G3DSA:2.40.30.10 311 410 1.9E-37 T 06-07-2017 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF50447 310 407 3.09E-35 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 SUPERFAMILY SSF50447 255 281 3.09E-35 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Gene3D G3DSA:3.30.70.870 411 485 6.4E-39 T 06-07-2017 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 109.878 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Pfam PF03764 Elongation factor G, domain IV 484 604 1.5E-47 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Gene3D G3DSA:3.30.230.10 489 602 5.6E-50 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS17045 aa3c33669fea1c39f9a6227adddc8fd5 702 Pfam PF00679 Elongation factor G C-terminus 606 694 5.4E-32 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 Gene3D G3DSA:3.30.565.10 13 128 3.6E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 171 334 8.7E-13 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 SUPERFAMILY SSF81606 146 335 3.66E-16 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 SMART SM00331 143 336 5.0E-6 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 Pfam PF13581 Histidine kinase-like ATPase domain 10 121 2.9E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26660 6daa751cf9c064d317ad3bd87fdc5fd6 339 SUPERFAMILY SSF55874 29 128 1.99E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 Gene3D G3DSA:3.20.20.70 8 335 1.3E-147 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 332 1.1E-137 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 SUPERFAMILY SSF51569 7 335 3.37E-142 T 06-07-2017 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 2.4E-57 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 SMART SM01004 10 334 5.7E-233 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 PIRSF PIRSF001415 3 337 3.5E-145 T 06-07-2017 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS27475 6ae90b89666e0ef31ff062185193efb1 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 06-07-2017 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 452 2.1E-209 T 06-07-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 SUPERFAMILY SSF53623 98 307 3.27E-47 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Gene3D G3DSA:3.40.1190.10 92 312 3.5E-85 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Gene3D G3DSA:3.90.190.20 313 452 2.8E-34 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 SUPERFAMILY SSF53244 310 452 2.22E-36 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Pfam PF08245 Mur ligase middle domain 108 291 1.0E-20 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 372 1.9E-10 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 SUPERFAMILY SSF51984 1 90 4.71E-19 T 06-07-2017 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 453 57.727 T 06-07-2017 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Gene3D G3DSA:3.40.50.720 1 90 3.2E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24885 81e97448a5f5704fa63a95f71c6a6df7 458 Pfam PF01225 Mur ligase family, catalytic domain 2 99 2.9E-16 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS21175 09ba38a7d5508751736ec07f93e517ff 162 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 138 4.5E-17 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS21175 09ba38a7d5508751736ec07f93e517ff 162 SMART SM00226 5 142 4.0E-32 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS21175 09ba38a7d5508751736ec07f93e517ff 162 Gene3D G3DSA:3.40.50.270 4 140 1.6E-39 T 06-07-2017 CAL12_RS21175 09ba38a7d5508751736ec07f93e517ff 162 SUPERFAMILY SSF52788 5 142 4.06E-38 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS26405 4a4bb03cb6caca9bb08799d0e637ea7f 429 Gene3D G3DSA:3.40.50.980 136 257 5.0E-9 T 06-07-2017 CAL12_RS26405 4a4bb03cb6caca9bb08799d0e637ea7f 429 Gene3D G3DSA:3.30.300.30 332 417 1.3E-11 T 06-07-2017 CAL12_RS26405 4a4bb03cb6caca9bb08799d0e637ea7f 429 Pfam PF00501 AMP-binding enzyme 142 294 3.4E-11 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS26405 4a4bb03cb6caca9bb08799d0e637ea7f 429 SUPERFAMILY SSF56801 133 399 1.44E-31 T 06-07-2017 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Pfam PF09312 SurA N-terminal domain 74 190 5.4E-34 T 06-07-2017 IPR015391 SurA N-terminal CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 SUPERFAMILY SSF54534 386 487 2.81E-31 T 06-07-2017 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 424 444 - T 06-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Hamap MF_01183 Chaperone SurA [surA]. 10 530 32.404 T 06-07-2017 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 SUPERFAMILY SSF54534 244 347 3.07E-26 T 06-07-2017 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 SUPERFAMILY SSF109998 242 273 2.35E-40 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 SUPERFAMILY SSF109998 74 213 2.35E-40 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Pfam PF00639 PPIC-type PPIASE domain 392 482 2.0E-25 T 06-07-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Pfam PF00639 PPIC-type PPIASE domain 250 341 6.2E-17 T 06-07-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Gene3D G3DSA:3.10.50.40 240 350 2.5E-28 T 06-07-2017 CAL12_RS06295 fd49615df215abab50a4a777a227471e 543 Gene3D G3DSA:3.10.50.40 384 494 3.0E-36 T 06-07-2017 CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 437 456 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 547 8.8E-39 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 SUPERFAMILY SSF52467 189 340 8.28E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 SUPERFAMILY SSF52467 372 392 8.28E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 SUPERFAMILY SSF52518 376 552 6.08E-55 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 SUPERFAMILY SSF52518 3 179 4.12E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Gene3D G3DSA:3.40.50.970 371 555 7.0E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 4.2E-54 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Gene3D G3DSA:3.40.50.1220 189 345 2.4E-45 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 5.9E-31 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS22345 4020872a96f0aad979e272cf1500ee19 564 Gene3D G3DSA:3.40.50.970 2 179 7.7E-59 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS26675 d862709142d271ceb23aeb08ab4c0cfc 288 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 8 110 1.3E-25 T 06-07-2017 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain CAL12_RS26675 d862709142d271ceb23aeb08ab4c0cfc 288 Gene3D G3DSA:3.30.750.24 163 255 3.6E-14 T 06-07-2017 IPR002645 STAS domain CAL12_RS26675 d862709142d271ceb23aeb08ab4c0cfc 288 SUPERFAMILY SSF52091 159 255 3.14E-18 T 06-07-2017 IPR002645 STAS domain CAL12_RS26675 d862709142d271ceb23aeb08ab4c0cfc 288 Pfam PF01740 STAS domain 165 267 1.0E-9 T 06-07-2017 IPR002645 STAS domain CAL12_RS25705 92ae65af3362097b57510e5cb361d953 325 SUPERFAMILY SSF161098 90 305 5.4E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25705 92ae65af3362097b57510e5cb361d953 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 318 2.2E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25705 92ae65af3362097b57510e5cb361d953 325 Gene3D G3DSA:1.10.3720.10 89 316 1.2E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 154 757 6.2E-175 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF81653 242 339 1.31E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Gene3D G3DSA:3.40.1110.10 456 567 1.4E-21 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 576 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 441 455 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 587 597 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 670 682 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 647 666 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 289 303 7.8E-30 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 ProSitePatterns PS01047 Heavy-metal-associated domain. 14 43 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF56784 439 459 4.51E-58 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF56784 498 754 4.51E-58 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 207 756 8.7E-114 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 727 2.6E-88 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00943 Copper-transporting ATPase signature 157 176 1.0E-9 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00943 Copper-transporting ATPase signature 362 376 1.0E-9 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00943 Copper-transporting ATPase signature 617 634 1.0E-9 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00943 Copper-transporting ATPase signature 209 228 1.0E-9 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 PRINTS PR00943 Copper-transporting ATPase signature 424 439 1.0E-9 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 172 756 7.0E-187 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Gene3D G3DSA:3.30.70.100 10 89 1.0E-25 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF55008 5 77 1.7E-20 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 443 449 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Pfam PF00122 E1-E2 ATPase 210 431 8.1E-70 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF81665 340 435 1.57E-15 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF81665 189 243 1.57E-15 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 SUPERFAMILY SSF81665 696 738 1.57E-15 T 06-07-2017 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Pfam PF00403 Heavy-metal-associated domain 12 72 1.2E-14 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Gene3D G3DSA:3.40.50.1000 568 715 2.9E-52 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Gene3D G3DSA:3.40.50.1000 412 455 2.9E-52 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Gene3D G3DSA:2.70.150.10 172 340 5.5E-35 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS11680 7ea22bf9fe70ce7bda47918db74f23d5 787 Pfam PF00702 haloacid dehalogenase-like hydrolase 439 661 4.7E-44 T 06-07-2017 CAL12_RS11805 998763376d5273e6e300f6a36df78484 192 SUPERFAMILY SSF160930 5 163 1.96E-61 T 06-07-2017 CAL12_RS11805 998763376d5273e6e300f6a36df78484 192 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 171 7.0E-85 T 06-07-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CAL12_RS11805 998763376d5273e6e300f6a36df78484 192 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 175 6.8E-81 T 06-07-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CAL12_RS11805 998763376d5273e6e300f6a36df78484 192 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 192 45.203 T 06-07-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CAL12_RS11805 998763376d5273e6e300f6a36df78484 192 PIRSF PIRSF003159 1 184 3.0E-81 T 06-07-2017 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 CAL12_RS08570 754051a7a0de0359c48f580dc0f35482 149 Gene3D G3DSA:3.10.129.10 14 145 8.1E-34 T 06-07-2017 IPR029069 HotDog domain CAL12_RS08570 754051a7a0de0359c48f580dc0f35482 149 SUPERFAMILY SSF54637 10 143 2.55E-30 T 06-07-2017 IPR029069 HotDog domain CAL12_RS08570 754051a7a0de0359c48f580dc0f35482 149 Pfam PF13279 Thioesterase-like superfamily 22 137 2.6E-15 T 06-07-2017 CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 SUPERFAMILY SSF52518 24 190 2.13E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 SUPERFAMILY SSF52518 404 598 1.72E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 26 189 1.3E-55 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 463 482 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 25 597 1.2E-212 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Gene3D G3DSA:3.40.50.970 25 189 7.4E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 SUPERFAMILY SSF52467 221 393 9.0E-58 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 227 364 2.8E-41 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Gene3D G3DSA:3.40.50.1220 222 387 2.9E-58 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Gene3D G3DSA:3.40.50.970 388 589 3.6E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS00445 4a72299d8225593f94e693a582232a1b 607 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 426 574 3.7E-51 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS22200 054e030c3c4617a8e6c5411bccd10cad 740 SUPERFAMILY SSF74650 11 232 2.61E-26 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS22200 054e030c3c4617a8e6c5411bccd10cad 740 SUPERFAMILY SSF51011 578 657 1.29E-19 T 06-07-2017 CAL12_RS22200 054e030c3c4617a8e6c5411bccd10cad 740 SUPERFAMILY SSF51445 235 576 1.79E-37 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS22200 054e030c3c4617a8e6c5411bccd10cad 740 Pfam PF01055 Glycosyl hydrolases family 31 227 662 3.7E-72 T 06-07-2017 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CAL12_RS00435 0462e56a849a8d269f5ac6d3b05695b1 162 Pfam PF00856 SET domain 19 122 5.2E-19 T 06-07-2017 IPR001214 SET domain GO:0005515 CAL12_RS00435 0462e56a849a8d269f5ac6d3b05695b1 162 SUPERFAMILY SSF82199 8 148 1.85E-40 T 06-07-2017 CAL12_RS00435 0462e56a849a8d269f5ac6d3b05695b1 162 Gene3D G3DSA:2.170.270.10 11 150 4.2E-40 T 06-07-2017 CAL12_RS00435 0462e56a849a8d269f5ac6d3b05695b1 162 SMART SM00317 7 128 2.5E-28 T 06-07-2017 IPR001214 SET domain GO:0005515 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 SUPERFAMILY SSF48173 198 470 2.62E-103 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 Gene3D G3DSA:1.10.579.10 287 471 2.5E-72 T 06-07-2017 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 329 341 - T 06-07-2017 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 Pfam PF03441 FAD binding domain of DNA photolyase 279 469 2.2E-79 T 06-07-2017 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 Pfam PF00875 DNA photolyase 3 168 1.6E-41 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 SUPERFAMILY SSF52425 3 185 1.57E-50 T 06-07-2017 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 Gene3D G3DSA:3.40.50.620 2 162 5.4E-40 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 Gene3D G3DSA:1.25.40.80 206 286 3.2E-38 T 06-07-2017 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 PRINTS PR00147 DNA photolyase signature 349 367 1.0E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 PRINTS PR00147 DNA photolyase signature 329 345 1.0E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 PRINTS PR00147 DNA photolyase signature 142 158 1.0E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAL12_RS13040 f18876c7f2da8f560e211ab17d7886c8 478 PRINTS PR00147 DNA photolyase signature 388 402 1.0E-24 T 06-07-2017 IPR002081 Cryptochrome/DNA photolyase class 1 CAL12_RS18035 2a8a6ab679ed246dd2a68302ba92f018 463 Pfam PF02646 RmuC family 151 437 6.6E-76 T 06-07-2017 IPR003798 DNA recombination RmuC CAL12_RS18035 2a8a6ab679ed246dd2a68302ba92f018 463 SUPERFAMILY SSF58113 53 206 2.48E-6 T 06-07-2017 CAL12_RS12570 7cfbe86eabe0070ceaef0b247059d55b 423 Gene3D G3DSA:2.40.50.100 208 237 1.5E-12 T 06-07-2017 CAL12_RS12570 7cfbe86eabe0070ceaef0b247059d55b 423 Gene3D G3DSA:2.40.50.100 101 133 1.5E-12 T 06-07-2017 CAL12_RS12570 7cfbe86eabe0070ceaef0b247059d55b 423 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 101 316 8.5E-28 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS12570 7cfbe86eabe0070ceaef0b247059d55b 423 SUPERFAMILY SSF111369 90 321 6.54E-37 T 06-07-2017 CAL12_RS12570 7cfbe86eabe0070ceaef0b247059d55b 423 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 75 396 4.1E-64 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 162 1.4E-35 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 SUPERFAMILY SSF51735 3 165 2.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 SUPERFAMILY SSF48179 168 289 1.09E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 285 3.2E-16 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 Gene3D G3DSA:3.40.50.720 2 164 7.2E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 Gene3D G3DSA:1.10.1040.10 169 289 3.1E-27 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 PIRSF PIRSF000103 1 293 1.3E-65 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS16815 011b53a98bb5e55a7083c59836e65f89 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 SUPERFAMILY SSF46785 13 86 1.47E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 Gene3D G3DSA:3.30.450.40 78 234 8.3E-30 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 Pfam PF09339 IclR helix-turn-helix domain 15 64 5.7E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 Pfam PF01614 Bacterial transcriptional regulator 161 229 7.1E-10 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 SMART SM00346 13 102 8.4E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 Gene3D G3DSA:1.10.10.10 3 73 4.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10560 4b23a51ab3d24cb57cf5250e2b2ad28f 246 SUPERFAMILY SSF55781 78 233 9.16E-28 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS21755 dc2f0f9a2e695b4d92eed757c8b4fda7 346 SUPERFAMILY SSF53850 126 305 1.27E-8 T 06-07-2017 CAL12_RS21755 dc2f0f9a2e695b4d92eed757c8b4fda7 346 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 341 6.2E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21755 dc2f0f9a2e695b4d92eed757c8b4fda7 346 PIRSF PIRSF017082 15 346 1.5E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13070 a94fc45018ca27df1651330c067f9403 437 SUPERFAMILY SSF103473 35 423 3.14E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13070 a94fc45018ca27df1651330c067f9403 437 Gene3D G3DSA:1.20.1250.20 40 222 5.6E-16 T 06-07-2017 CAL12_RS13070 a94fc45018ca27df1651330c067f9403 437 Gene3D G3DSA:1.20.1250.20 246 423 1.5E-14 T 06-07-2017 CAL12_RS13070 a94fc45018ca27df1651330c067f9403 437 Pfam PF07690 Major Facilitator Superfamily 47 367 6.5E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 4 396 7.5E-111 T 06-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 164 1.7E-6 T 06-07-2017 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.7E-6 T 06-07-2017 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 SUPERFAMILY SSF160996 190 342 6.8E-32 T 06-07-2017 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 Gene3D G3DSA:1.10.8.260 263 326 2.1E-8 T 06-07-2017 IPR023166 HI0933 insert-like domain CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 Gene3D G3DSA:3.50.50.60 343 397 4.1E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 Gene3D G3DSA:3.50.50.60 2 186 4.1E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 Pfam PF03486 HI0933-like protein 2 396 9.4E-129 T 06-07-2017 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 Gene3D G3DSA:2.40.30.10 188 262 5.7E-25 T 06-07-2017 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 SUPERFAMILY SSF51905 341 398 1.69E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02640 409e0a1cf7dc57f18a2bd6ab49b6b11d 398 SUPERFAMILY SSF51905 1 188 1.69E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 Gene3D G3DSA:1.10.1040.10 181 279 8.0E-31 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 SUPERFAMILY SSF51735 12 172 6.68E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 SUPERFAMILY SSF48179 174 283 4.08E-25 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 12 132 3.7E-13 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 Gene3D G3DSA:3.40.50.720 12 180 2.6E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 PIRSF PIRSF000103 5 288 1.0E-25 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS13715 784cf53fded943195888d45f0c4dfa2b 303 Pfam PF09130 Domain of unknown function (DUF1932) 201 272 1.2E-14 T 06-07-2017 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 Gene3D G3DSA:3.40.630.10 425 486 4.0E-45 T 06-07-2017 CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 Gene3D G3DSA:3.40.630.10 26 231 4.0E-45 T 06-07-2017 CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 Pfam PF07687 Peptidase dimerisation domain 219 383 8.5E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 Gene3D G3DSA:3.30.70.360 232 394 4.9E-29 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 SUPERFAMILY SSF53187 19 221 1.04E-44 T 06-07-2017 CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 SUPERFAMILY SSF53187 400 486 1.04E-44 T 06-07-2017 CAL12_RS17060 8dbf6ff51b4f71f828028d8fc3d9c9c2 490 Pfam PF01546 Peptidase family M20/M25/M40 107 485 3.6E-22 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS14390 d3a15d2b7a53d258249ab79d7c9710e6 509 SUPERFAMILY SSF56954 21 493 2.49E-99 T 06-07-2017 CAL12_RS14390 d3a15d2b7a53d258249ab79d7c9710e6 509 Gene3D G3DSA:1.20.1600.10 69 493 4.5E-94 T 06-07-2017 CAL12_RS14390 d3a15d2b7a53d258249ab79d7c9710e6 509 Pfam PF02321 Outer membrane efflux protein 86 278 1.5E-20 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS14390 d3a15d2b7a53d258249ab79d7c9710e6 509 Pfam PF02321 Outer membrane efflux protein 310 474 5.3E-26 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS14390 d3a15d2b7a53d258249ab79d7c9710e6 509 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 28 490 1.1E-94 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS25060 efb7630af8e7953954eac38db15e152f 314 Pfam PF07859 alpha/beta hydrolase fold 80 268 4.3E-16 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS25060 efb7630af8e7953954eac38db15e152f 314 Gene3D G3DSA:3.40.50.1820 35 283 4.4E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25060 efb7630af8e7953954eac38db15e152f 314 SUPERFAMILY SSF53474 13 275 1.12E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 SUPERFAMILY SSF55781 79 261 3.2E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 Pfam PF01614 Bacterial transcriptional regulator 139 257 3.4E-12 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 Gene3D G3DSA:3.30.450.40 85 260 5.1E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 Pfam PF09339 IclR helix-turn-helix domain 16 65 5.1E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 SMART SM00346 13 105 2.8E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 Gene3D G3DSA:1.10.10.10 15 84 6.8E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27165 1af925dff3e22b26cc6481e1fd8d8673 280 SUPERFAMILY SSF46785 16 85 2.89E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SUPERFAMILY SSF55874 597 680 4.96E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Gene3D G3DSA:3.40.50.2300 762 893 6.6E-19 T 06-07-2017 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Gene3D G3DSA:3.40.50.300 347 578 1.5E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SUPERFAMILY SSF90123 17 336 1.24E-53 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Pfam PF00072 Response regulator receiver domain 766 885 1.9E-10 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Pfam PF00664 ABC transporter transmembrane region 31 298 6.8E-30 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SMART SM00382 372 558 3.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Gene3D G3DSA:1.20.1560.10 18 330 4.5E-55 T 06-07-2017 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SMART SM00448 764 887 1.2E-10 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Gene3D G3DSA:3.30.565.10 596 680 3.2E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 Pfam PF00005 ABC transporter 365 512 5.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SUPERFAMILY SSF52172 762 892 2.85E-18 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22960 b71ba71a51c987dde42b96382577f62a 898 SUPERFAMILY SSF52540 339 582 1.13E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21705 670f5e794f0f33dea01f62dc9801c286 173 SUPERFAMILY SSF55729 9 163 3.88E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS21705 670f5e794f0f33dea01f62dc9801c286 173 Pfam PF13420 Acetyltransferase (GNAT) domain 17 156 4.9E-18 T 06-07-2017 CAL12_RS21705 670f5e794f0f33dea01f62dc9801c286 173 Gene3D G3DSA:3.40.630.30 9 168 5.3E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 Pfam PF01614 Bacterial transcriptional regulator 127 235 1.3E-19 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 Pfam PF09339 IclR helix-turn-helix domain 11 60 3.0E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 SUPERFAMILY SSF55781 82 248 5.76E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 Gene3D G3DSA:3.30.450.40 82 248 7.8E-40 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 SUPERFAMILY SSF46785 9 80 7.87E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 Gene3D G3DSA:1.10.10.10 4 66 1.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03125 f2f338a5f35536e7e9ab1779920cf94f 250 SMART SM00346 9 99 0.002 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS14775 638d6e1fb670900fdcb2352413af2be4 245 SUPERFAMILY SSF53639 8 209 7.06E-47 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS14775 638d6e1fb670900fdcb2352413af2be4 245 Gene3D G3DSA:3.40.225.10 8 211 2.8E-44 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS14775 638d6e1fb670900fdcb2352413af2be4 245 SMART SM01007 13 192 7.4E-37 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS14775 638d6e1fb670900fdcb2352413af2be4 245 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 191 4.8E-31 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS05505 6c2ed8e2d6aa8b14170f7217cf731478 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 1.9E-30 T 06-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 CAL12_RS05505 6c2ed8e2d6aa8b14170f7217cf731478 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 19.343 T 06-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 CAL12_RS05505 6c2ed8e2d6aa8b14170f7217cf731478 84 Gene3D G3DSA:3.30.1070.10 34 83 2.9E-21 T 06-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 CAL12_RS05505 6c2ed8e2d6aa8b14170f7217cf731478 84 SUPERFAMILY SSF55229 33 83 2.62E-15 T 06-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 CAL12_RS05505 6c2ed8e2d6aa8b14170f7217cf731478 84 Pfam PF03776 Septum formation topological specificity factor MinE 14 82 5.1E-27 T 06-07-2017 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SUPERFAMILY SSF52540 550 645 1.41E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SUPERFAMILY SSF52540 189 312 1.41E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SMART SM00491 576 706 4.9E-30 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Gene3D G3DSA:3.40.50.300 560 645 1.4E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SUPERFAMILY SSF52540 665 690 2.59E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SUPERFAMILY SSF52540 191 248 2.59E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 SUPERFAMILY SSF52540 6 113 2.59E-23 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Gene3D G3DSA:3.40.50.300 33 114 4.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Gene3D G3DSA:3.40.50.300 190 239 4.5E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Pfam PF13307 Helicase C-terminal domain 556 719 1.6E-31 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Pfam PF06733 DEAD_2 178 253 9.2E-5 T 06-07-2017 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CAL12_RS19190 821516e11951da51e10e1cedd49f1f8e 753 Pfam PF00270 DEAD/DEAH box helicase 33 87 3.0E-4 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 Pfam PF00107 Zinc-binding dehydrogenase 155 282 1.4E-14 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 SMART SM00829 12 324 9.2E-13 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.0E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 Gene3D G3DSA:3.90.180.10 1 153 8.7E-34 T 06-07-2017 IPR011032 GroES-like CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 Gene3D G3DSA:3.40.50.720 154 264 2.6E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 SUPERFAMILY SSF50129 1 151 5.02E-31 T 06-07-2017 IPR011032 GroES-like CAL12_RS00105 46c854f5b350cbaa91ac50f94df04e1c 328 SUPERFAMILY SSF51735 117 289 3.05E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 SMART SM01130 4 296 2.1E-79 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 Gene3D G3DSA:3.20.20.70 2 290 1.1E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 SUPERFAMILY SSF51569 3 290 1.15E-76 T 06-07-2017 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 Pfam PF00701 Dihydrodipicolinate synthetase family 6 290 1.1E-51 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 5.9E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.9E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.9E-10 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06890 a3c334c7d5e9044c01c0663213359c58 298 PIRSF PIRSF001365 1 297 3.9E-70 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 Gene3D G3DSA:1.20.120.530 89 228 1.2E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 SUPERFAMILY SSF46785 6 78 5.46E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.4E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 SMART SM00345 15 74 7.1E-25 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 SMART SM00895 93 219 1.4E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 Pfam PF07729 FCD domain 95 218 1.3E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 Gene3D G3DSA:1.10.10.10 7 76 5.6E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 SUPERFAMILY SSF48008 89 226 7.06E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03005 9fba6bfe17e604be6b788dd6312bd027 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 74 1.4E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 Gene3D G3DSA:1.10.10.60 181 237 9.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 Pfam PF12833 Helix-turn-helix domain 206 282 5.8E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 SUPERFAMILY SSF46689 186 234 5.15E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 SMART SM00342 200 282 1.2E-29 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 2.7E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 2.7E-6 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 237 278 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 SUPERFAMILY SSF46689 237 282 1.97E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09310 cb30ee620715d6c0126afb41979bde59 284 Gene3D G3DSA:1.10.10.60 238 282 9.8E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10435 d586533ce523a007b9273f0749e7b5c3 278 Gene3D G3DSA:1.10.3720.10 4 267 1.0E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10435 d586533ce523a007b9273f0749e7b5c3 278 SUPERFAMILY SSF161098 3 263 2.88E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10435 d586533ce523a007b9273f0749e7b5c3 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 270 2.3E-7 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 SUPERFAMILY SSF51391 118 322 5.1E-42 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 SUPERFAMILY SSF55811 8 116 1.76E-33 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 PRINTS PR00502 NUDIX hydrolase family signature 35 49 3.2E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 PRINTS PR00502 NUDIX hydrolase family signature 49 64 3.2E-7 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 Gene3D G3DSA:3.20.20.70 130 322 6.0E-39 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 Pfam PF02581 Thiamine monophosphate synthase/TENI 149 319 3.5E-37 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 Gene3D G3DSA:3.90.79.10 8 114 8.2E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS25085 184c9c4e37913bfd3ef63411aad2c2f0 324 Pfam PF00293 NUDIX domain 9 112 2.0E-18 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS04485 a09c7c5f79d10c972ffc6869415cacc8 333 SUPERFAMILY SSF53850 120 289 3.12E-10 T 06-07-2017 CAL12_RS04485 a09c7c5f79d10c972ffc6869415cacc8 333 PIRSF PIRSF017082 4 333 8.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04485 a09c7c5f79d10c972ffc6869415cacc8 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 59 329 1.7E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 SMART SM00382 351 528 3.9E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 Gene3D G3DSA:3.40.50.300 315 532 9.6E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 Gene3D G3DSA:1.20.1560.10 5 302 1.3E-22 T 06-07-2017 CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 5 529 1.6E-136 T 06-07-2017 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 SUPERFAMILY SSF90123 4 302 5.89E-28 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 SUPERFAMILY SSF52540 313 535 9.77E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 Pfam PF00005 ABC transporter 344 479 2.4E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS11095 fd2d5b4b27e40f7688508d41d094a81e 552 ProSitePatterns PS00211 ABC transporters family signature. 452 466 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 Pfam PF01614 Bacterial transcriptional regulator 209 331 1.5E-30 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 Gene3D G3DSA:1.10.10.10 80 150 1.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 SMART SM00346 90 180 1.9E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 Gene3D G3DSA:3.30.450.40 163 335 4.6E-48 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 SUPERFAMILY SSF55781 163 334 4.05E-42 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 Pfam PF09339 IclR helix-turn-helix domain 94 143 4.7E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS03700 ca78da200b961988ef1f6e93ddb9f608 346 SUPERFAMILY SSF46785 91 162 2.05E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24260 6fc019890c4ab70b4e72022748d3bcfa 306 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 31 302 1.6E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24260 6fc019890c4ab70b4e72022748d3bcfa 306 PIRSF PIRSF017082 1 306 8.8E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24260 6fc019890c4ab70b4e72022748d3bcfa 306 SUPERFAMILY SSF53850 103 260 4.02E-11 T 06-07-2017 CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 184 206 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 Gene3D G3DSA:3.40.50.720 102 275 8.7E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 SUPERFAMILY SSF51735 96 275 1.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 274 4.7E-57 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 SUPERFAMILY SSF52283 14 128 6.17E-23 T 06-07-2017 CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 299 1.0E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 Gene3D G3DSA:3.40.50.720 5 101 1.2E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13400 c3f453961b1b4f6f9fc5b5ba9cbe0193 303 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Pfam PF00501 AMP-binding enzyme 30 462 8.8E-107 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 SUPERFAMILY SSF56801 21 557 1.16E-146 T 06-07-2017 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Gene3D G3DSA:3.40.50.980 220 380 1.4E-39 T 06-07-2017 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Gene3D G3DSA:2.30.38.10 381 453 4.6E-30 T 06-07-2017 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Gene3D G3DSA:3.30.300.30 459 558 7.5E-32 T 06-07-2017 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 545 2.8E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Gene3D G3DSA:3.40.50.980 195 219 4.8E-38 T 06-07-2017 CAL12_RS22215 503ea4b68e78588f4a89b2f69f688377 582 Gene3D G3DSA:3.40.50.980 24 136 4.8E-38 T 06-07-2017 CAL12_RS25310 2bae1f3fe1c17674d3984c32b41a86b5 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 97 6.1E-18 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAL12_RS25310 2bae1f3fe1c17674d3984c32b41a86b5 102 SUPERFAMILY SSF141000 3 100 9.15E-23 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAL12_RS25310 2bae1f3fe1c17674d3984c32b41a86b5 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 102 2.2E-23 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAL12_RS25310 2bae1f3fe1c17674d3984c32b41a86b5 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 102 21.444 T 06-07-2017 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CAL12_RS18165 8de2fb72e75796951e185b91aa264c14 263 SUPERFAMILY SSF52096 9 263 1.27E-77 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18165 8de2fb72e75796951e185b91aa264c14 263 Gene3D G3DSA:1.10.12.10 206 263 4.6E-20 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS18165 8de2fb72e75796951e185b91aa264c14 263 Gene3D G3DSA:3.90.226.10 11 205 7.5E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18165 8de2fb72e75796951e185b91aa264c14 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 262 1.6E-54 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS25480 2c88306d8c27253849d90c8be1dacf87 325 SUPERFAMILY SSF53850 115 280 5.72E-12 T 06-07-2017 CAL12_RS25480 2c88306d8c27253849d90c8be1dacf87 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 4.0E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25480 2c88306d8c27253849d90c8be1dacf87 325 PIRSF PIRSF017082 1 325 1.8E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 06-07-2017 IPR018192 Ribosomal protein S5, N-terminal, conserved site CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 SUPERFAMILY SSF54768 15 82 2.83E-20 T 06-07-2017 CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 8.5E-29 T 06-07-2017 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.534 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 Gene3D G3DSA:3.30.230.10 83 166 1.4E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 Gene3D G3DSA:3.30.160.20 16 79 4.6E-25 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 SUPERFAMILY SSF54211 86 166 1.62E-25 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 81 8.3E-24 T 06-07-2017 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS27540 23a7ea09da86feced679fca59f6afffe 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 170 1.2E-63 T 06-07-2017 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 SUPERFAMILY SSF54534 127 222 2.03E-30 T 06-07-2017 CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 Gene3D G3DSA:3.10.50.40 121 242 9.1E-43 T 06-07-2017 CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 Pfam PF13623 SurA N-terminal domain 19 77 1.8E-7 T 06-07-2017 CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 Pfam PF13616 PPIC-type PPIASE domain 122 220 1.4E-23 T 06-07-2017 CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 SUPERFAMILY SSF109998 21 156 2.47E-22 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS19550 31b50f67d7a4604e28cee29b36139220 258 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 157 178 - T 06-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 CAL12_RS00400 2a8b7bba26cfe1b736c0ab5c9bd36e4d 292 SUPERFAMILY SSF53474 35 253 3.02E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00400 2a8b7bba26cfe1b736c0ab5c9bd36e4d 292 Gene3D G3DSA:3.40.50.1820 32 258 2.8E-63 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00400 2a8b7bba26cfe1b736c0ab5c9bd36e4d 292 Pfam PF07859 alpha/beta hydrolase fold 52 253 1.6E-53 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 19 32 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 Gene3D G3DSA:3.40.50.720 14 176 5.3E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 PIRSF PIRSF000103 10 301 1.6E-72 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 Gene3D G3DSA:1.10.1040.10 179 300 4.3E-42 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 SUPERFAMILY SSF48179 178 300 2.83E-40 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 SUPERFAMILY SSF51735 15 176 9.93E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 179 298 2.8E-34 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS22580 0682e31009e7c8e9aff3987905717e73 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 176 3.4E-47 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 Pfam PF09339 IclR helix-turn-helix domain 18 68 5.0E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 SMART SM00346 16 106 4.5E-23 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 Gene3D G3DSA:1.10.10.10 11 85 2.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 Pfam PF01614 Bacterial transcriptional regulator 135 260 9.7E-36 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 SUPERFAMILY SSF46785 16 89 2.87E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 SUPERFAMILY SSF55781 83 262 7.85E-47 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS10565 977832b773843ac5960deb4dec7de5a9 276 Gene3D G3DSA:3.30.450.40 86 262 1.6E-52 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 Gene3D G3DSA:3.40.1410.10 91 227 2.1E-49 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 SMART SM00866 94 231 1.7E-36 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 6.0E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 6.0E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 9 236 3.4E-92 T 06-07-2017 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 SMART SM00345 14 73 1.9E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 Pfam PF07702 UTRA domain 94 231 3.5E-35 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 SUPERFAMILY SSF64288 61 234 1.73E-44 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 2.1E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 Gene3D G3DSA:1.10.10.10 8 78 1.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16065 91fa8c70912c0cdd37eceeb32d8bed4d 253 SUPERFAMILY SSF46785 7 77 1.74E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14870 d585eaeb9c17b4fc66a14e942a470702 378 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 104 375 3.8E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14870 d585eaeb9c17b4fc66a14e942a470702 378 SUPERFAMILY SSF53850 165 340 5.25E-15 T 06-07-2017 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 TIGRFAM TIGR02546 III_secr_ATP: type III secretion apparatus H+-transporting two-sector ATPase 19 438 6.0E-191 T 06-07-2017 IPR013380 ATPase, type III secretion system, H+-transporting GO:0005524|GO:0005737|GO:0006754|GO:0030254|GO:0030257|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 SMART SM00382 162 342 2.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 14 435 3.6E-170 T 06-07-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 90 1.5E-8 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 349 358 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 358 2.7E-74 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 Gene3D G3DSA:3.40.50.300 123 407 1.9E-93 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22075 55d354b16bab79b350348469582d82ed 440 SUPERFAMILY SSF52540 95 364 1.55E-95 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 1.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 Gene3D G3DSA:3.40.190.10 204 275 4.1E-11 T 06-07-2017 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 Gene3D G3DSA:1.10.10.10 12 97 2.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 Pfam PF03466 LysR substrate binding domain 99 304 1.3E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 SUPERFAMILY SSF46785 11 120 1.01E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 SUPERFAMILY SSF53850 99 310 3.53E-27 T 06-07-2017 CAL12_RS20740 1a3fec1f6f3165da691a9714528a1968 318 Gene3D G3DSA:3.40.190.10 103 203 3.7E-16 T 06-07-2017 CAL12_RS07300 d067c0682b5868096f9439383cc6be7d 287 SMART SM00382 44 237 1.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07300 d067c0682b5868096f9439383cc6be7d 287 SUPERFAMILY SSF52540 14 250 1.32E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07300 d067c0682b5868096f9439383cc6be7d 287 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07300 d067c0682b5868096f9439383cc6be7d 287 Pfam PF00005 ABC transporter 35 174 4.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07300 d067c0682b5868096f9439383cc6be7d 287 Gene3D G3DSA:3.40.50.300 13 228 1.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 79 8.6E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 SMART SM00895 89 210 7.1E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 SMART SM00345 21 79 2.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 Pfam PF07729 FCD domain 89 209 2.6E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 Gene3D G3DSA:1.10.10.10 13 80 2.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 Gene3D G3DSA:1.20.120.530 83 220 2.7E-42 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 SUPERFAMILY SSF48008 86 217 1.54E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS21165 a37319d9f6a1aaeca00bd1a9d5d4db0b 226 SUPERFAMILY SSF46785 14 83 1.42E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 Pfam PF03466 LysR substrate binding domain 89 294 2.0E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 Gene3D G3DSA:3.40.190.10 90 178 4.6E-27 T 06-07-2017 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 SUPERFAMILY SSF46785 6 88 1.91E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 Gene3D G3DSA:1.10.10.10 6 86 5.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.4E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 SUPERFAMILY SSF53850 93 294 2.06E-35 T 06-07-2017 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00345 4bdd79a611954cad7adec093786feaab 295 Gene3D G3DSA:3.40.190.10 179 263 2.1E-20 T 06-07-2017 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 Gene3D G3DSA:3.40.190.10 177 258 2.6E-28 T 06-07-2017 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 SUPERFAMILY SSF46785 1 110 2.97E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 Gene3D G3DSA:3.40.190.10 90 176 3.5E-18 T 06-07-2017 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 Pfam PF03466 LysR substrate binding domain 89 289 3.1E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 SUPERFAMILY SSF53850 90 290 1.28E-37 T 06-07-2017 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22225 f94a02bc7c41d4d18adfe4b1f588c42e 290 Gene3D G3DSA:1.10.10.10 1 79 1.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 Gene3D G3DSA:1.10.10.10 4 89 1.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 Pfam PF03466 LysR substrate binding domain 89 292 2.3E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.0E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 Gene3D G3DSA:3.40.190.10 92 178 4.3E-8 T 06-07-2017 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 SUPERFAMILY SSF53850 91 294 5.43E-32 T 06-07-2017 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 Gene3D G3DSA:3.40.190.10 179 263 1.8E-13 T 06-07-2017 CAL12_RS14570 cd6d66c671cf784ed54fc89bb0622aa9 302 SUPERFAMILY SSF46785 3 110 1.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 SUPERFAMILY SSF56104 6 292 2.71E-101 T 06-07-2017 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 Gene3D G3DSA:3.30.470.20 118 248 4.4E-52 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 06-07-2017 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 292 1.3E-78 T 06-07-2017 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 Gene3D G3DSA:3.30.200.20 4 117 4.3E-41 T 06-07-2017 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 Pfam PF01259 SAICAR synthetase 16 268 3.4E-100 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05215 3de0415f053b53c16ddacde5bba63c8b 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 25.464 T 06-07-2017 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.3E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 Gene3D G3DSA:3.40.190.10 91 207 1.9E-14 T 06-07-2017 CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 SUPERFAMILY SSF53850 91 283 9.77E-30 T 06-07-2017 CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 SUPERFAMILY SSF46785 5 112 2.08E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 Pfam PF03466 LysR substrate binding domain 91 285 6.8E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 Gene3D G3DSA:1.10.10.10 6 87 2.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02005 1bafb1eaf0cf464eeca3810d228b7dbf 310 Gene3D G3DSA:3.40.190.10 208 262 9.4E-8 T 06-07-2017 CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 1 205 1.2E-55 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 369 9.5E-24 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 Gene3D G3DSA:3.40.50.300 1 224 3.7E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 Gene3D G3DSA:3.30.1220.10 239 369 2.5E-16 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 SUPERFAMILY SSF52540 156 305 2.76E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 SUPERFAMILY SSF52540 1 132 2.76E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21630 05f2144a77239c5510829ae742af755c 397 SMART SM00833 252 369 1.9E-42 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 Pfam PF00691 OmpA family 64 146 7.2E-16 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 PRINTS PR01021 OMPA domain signature 95 110 4.9E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 PRINTS PR01021 OMPA domain signature 110 126 4.9E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 PRINTS PR01021 OMPA domain signature 65 87 4.9E-12 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 SUPERFAMILY SSF103088 58 161 1.16E-25 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22645 c051f7984154d061536dc92a0d4979c5 165 Gene3D G3DSA:3.30.1330.60 58 162 3.3E-25 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22415 016baf6e9e140210ccfd1c3dd9221567 397 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 387 2.6E-120 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CAL12_RS22415 016baf6e9e140210ccfd1c3dd9221567 397 Pfam PF01098 Cell cycle protein 29 388 1.6E-96 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAL12_RS22415 016baf6e9e140210ccfd1c3dd9221567 397 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 23 396 38.77 T 06-07-2017 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CAL12_RS20950 5173bea3af3cbe647cc0c41aafcd30d0 738 Pfam PF13515 Fusaric acid resistance protein-like 429 543 5.4E-16 T 06-07-2017 CAL12_RS20950 5173bea3af3cbe647cc0c41aafcd30d0 738 Pfam PF12805 FUSC-like inner membrane protein yccS 75 351 1.5E-63 T 06-07-2017 IPR032692 Integral membrane protein YccS, N-terminal CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 Gene3D G3DSA:3.40.190.10 184 267 1.8E-21 T 06-07-2017 CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 SUPERFAMILY SSF46785 13 93 1.73E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 Gene3D G3DSA:1.10.10.10 12 91 8.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 SUPERFAMILY SSF53850 96 304 4.34E-42 T 06-07-2017 CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 Pfam PF03466 LysR substrate binding domain 95 300 2.1E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 2.3E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14310 9a18abe8f289b23b89578ce27835062f 308 Gene3D G3DSA:3.40.190.10 99 183 1.2E-22 T 06-07-2017 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 557 44.455 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 557 1.1E-230 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 Pfam PF00920 Dehydratase family 35 554 3.0E-207 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 SUPERFAMILY SSF143975 4 378 1.28E-133 T 06-07-2017 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS22535 9b5a593cfc4107a9ab01ecd34ed7bd9d 561 SUPERFAMILY SSF52016 380 558 2.28E-56 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 Gene3D G3DSA:3.40.190.10 120 226 6.4E-27 T 06-07-2017 CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 SUPERFAMILY SSF53850 7 266 5.44E-59 T 06-07-2017 CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 SMART SM00062 34 266 5.3E-55 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 Gene3D G3DSA:3.40.190.10 227 268 6.2E-26 T 06-07-2017 CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 Gene3D G3DSA:3.40.190.10 31 119 6.2E-26 T 06-07-2017 CAL12_RS27710 e20ac85f7621accfb6d728a4ce5e0399 295 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 264 1.5E-46 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 270 1.2E-52 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 PIRSF PIRSF016184 1 289 1.3E-64 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 Gene3D G3DSA:3.10.310.10 122 278 2.2E-32 T 06-07-2017 CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 Gene3D G3DSA:3.10.310.10 4 117 9.6E-36 T 06-07-2017 CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 SUPERFAMILY SSF54506 3 289 9.31E-66 T 06-07-2017 CAL12_RS19135 169586400282fd1ca8fad066865c18d0 290 Pfam PF02567 Phenazine biosynthesis-like protein 10 275 6.1E-49 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 SUPERFAMILY SSF53850 88 287 5.19E-43 T 06-07-2017 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 Gene3D G3DSA:3.40.190.10 176 261 3.6E-14 T 06-07-2017 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 Pfam PF03466 LysR substrate binding domain 87 284 2.1E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.0E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 SUPERFAMILY SSF46785 1 110 1.17E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 Gene3D G3DSA:3.40.190.10 89 175 2.6E-17 T 06-07-2017 CAL12_RS14615 4209b0767fd71ab4d82262c9606e21ca 301 Gene3D G3DSA:1.10.10.10 1 79 1.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 PIRSF PIRSF002825 3 328 4.7E-82 T 06-07-2017 IPR026045 Ferric binding protein CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 Pfam PF13343 Bacterial extracellular solute-binding protein 77 308 1.8E-29 T 06-07-2017 CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 Gene3D G3DSA:3.40.190.10 127 258 5.0E-30 T 06-07-2017 CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 Gene3D G3DSA:3.40.190.10 259 318 2.8E-37 T 06-07-2017 CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 Gene3D G3DSA:3.40.190.10 9 123 2.8E-37 T 06-07-2017 CAL12_RS07200 3a435723aa9485deed2cb04d6174c23b 330 SUPERFAMILY SSF53850 27 324 2.03E-62 T 06-07-2017 CAL12_RS26215 4fb5290dab423f8cb0fd70b684e1382a 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 320 3.4E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26215 4fb5290dab423f8cb0fd70b684e1382a 323 PIRSF PIRSF017082 1 323 1.8E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26215 4fb5290dab423f8cb0fd70b684e1382a 323 SUPERFAMILY SSF53850 114 283 1.03E-11 T 06-07-2017 CAL12_RS08515 3eb86abd302f0c7bca0719f1ebb51192 336 SUPERFAMILY SSF54506 2 330 2.22E-120 T 06-07-2017 CAL12_RS08515 3eb86abd302f0c7bca0719f1ebb51192 336 Gene3D G3DSA:3.10.310.10 2 153 6.9E-65 T 06-07-2017 CAL12_RS08515 3eb86abd302f0c7bca0719f1ebb51192 336 PIRSF PIRSF029792 1 333 1.0E-131 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS08515 3eb86abd302f0c7bca0719f1ebb51192 336 Pfam PF05544 Proline racemase 8 331 1.1E-135 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS08515 3eb86abd302f0c7bca0719f1ebb51192 336 Gene3D G3DSA:3.10.310.10 154 320 1.2E-66 T 06-07-2017 CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 Gene3D G3DSA:3.90.180.10 5 154 1.4E-45 T 06-07-2017 IPR011032 GroES-like CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 Pfam PF13602 Zinc-binding dehydrogenase 192 325 4.0E-21 T 06-07-2017 CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 SMART SM00829 13 325 6.5E-25 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 92 6.9E-11 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 Gene3D G3DSA:3.40.50.720 155 239 1.8E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 SUPERFAMILY SSF50129 4 153 2.89E-42 T 06-07-2017 IPR011032 GroES-like CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 SUPERFAMILY SSF51735 121 295 6.31E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16435 3f7bf77abcfcf376ef90499c2643b181 328 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 149 170 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 250 1.2E-38 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 SUPERFAMILY SSF52374 3 271 1.8E-79 T 06-07-2017 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 3.3E-13 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 3.3E-13 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 3.3E-13 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 3.3E-13 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 3.3E-13 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 Gene3D G3DSA:3.40.50.620 187 236 8.9E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 Gene3D G3DSA:3.40.50.620 3 67 8.9E-42 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 Gene3D G3DSA:3.90.800.10 68 185 3.2E-18 T 06-07-2017 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 276 1.8E-111 T 06-07-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CAL12_RS00465 395b08c5b17686299bb975ea2f9f26c5 297 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 296 42.867 T 06-07-2017 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 CAL12_RS21765 5fc0fed678ecb3dd98fc029a750281ee 335 PIRSF PIRSF001439 2 318 2.9E-56 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS21765 5fc0fed678ecb3dd98fc029a750281ee 335 Gene3D G3DSA:3.40.50.720 131 290 1.8E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21765 5fc0fed678ecb3dd98fc029a750281ee 335 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 308 3.3E-46 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS21765 5fc0fed678ecb3dd98fc029a750281ee 335 Gene3D G3DSA:3.30.1780.10 5 130 3.1E-28 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS21765 5fc0fed678ecb3dd98fc029a750281ee 335 SUPERFAMILY SSF51735 5 315 1.25E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 Pfam PF03466 LysR substrate binding domain 104 305 1.4E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 Gene3D G3DSA:3.40.190.10 105 191 3.4E-11 T 06-07-2017 CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 SUPERFAMILY SSF53850 104 311 4.5E-40 T 06-07-2017 CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 SUPERFAMILY SSF46785 8 126 3.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 77 7.8E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 Gene3D G3DSA:1.10.10.10 15 96 7.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20510 4149bf7b9103c54ab8766849ce75ee3c 319 Gene3D G3DSA:3.40.190.10 192 277 1.2E-19 T 06-07-2017 CAL12_RS17785 16e88c32ea9df92cd7bfe114626d170c 485 PIRSF PIRSF004919 23 485 2.5E-134 T 06-07-2017 IPR025502 TldD CAL12_RS17785 16e88c32ea9df92cd7bfe114626d170c 485 SUPERFAMILY SSF111283 29 484 4.19E-132 T 06-07-2017 CAL12_RS17785 16e88c32ea9df92cd7bfe114626d170c 485 Pfam PF01523 Putative modulator of DNA gyrase 43 336 3.9E-64 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 SUPERFAMILY SSF54631 444 564 2.2E-12 T 06-07-2017 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 SUPERFAMILY SSF81340 10 435 8.11E-82 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 Gene3D G3DSA:1.10.3080.10 13 431 2.2E-68 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 Gene3D G3DSA:3.10.580.10 445 563 1.6E-13 T 06-07-2017 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 PRINTS PR00762 Chloride channel signature 168 187 1.8E-15 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 PRINTS PR00762 Chloride channel signature 366 382 1.8E-15 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 PRINTS PR00762 Chloride channel signature 384 403 1.8E-15 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 PRINTS PR00762 Chloride channel signature 115 134 1.8E-15 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 PRINTS PR00762 Chloride channel signature 332 352 1.8E-15 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS23040 fc02f3fc90c01947c2e9f4c60b8e51c0 570 Pfam PF00654 Voltage gated chloride channel 72 415 7.5E-69 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 817 924 2.0E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SUPERFAMILY SSF47384 698 769 1.24E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SMART SM00388 702 769 4.5E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:3.30.565.10 756 925 3.2E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SMART SM00387 813 925 3.7E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:1.20.120.620 436 535 5.5E-34 T 06-07-2017 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SUPERFAMILY SSF55781 549 694 7.36E-9 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Pfam PF13493 Domain of unknown function (DUF4118) 438 543 2.4E-26 T 06-07-2017 IPR025201 Sensor protein KdpD, transmembrane domain CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:1.10.287.130 698 755 7.5E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:3.30.450.40 542 685 5.5E-5 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Pfam PF13492 GAF domain 565 683 1.6E-10 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 PRINTS PR00344 Bacterial sensor protein C-terminal signature 850 864 5.6E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 PRINTS PR00344 Bacterial sensor protein C-terminal signature 909 922 5.6E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 PRINTS PR00344 Bacterial sensor protein C-terminal signature 883 901 5.6E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 878 5.6E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:3.40.50.300 26 234 4.3E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SUPERFAMILY SSF52402 258 354 2.51E-6 T 06-07-2017 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 27 235 4.3E-92 T 06-07-2017 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 SUPERFAMILY SSF55874 759 927 1.23E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Gene3D G3DSA:3.40.50.620 251 353 6.2E-5 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS21595 a8faa0edc5e81e08f7a0cee97ebd878c 952 Pfam PF00512 His Kinase A (phospho-acceptor) domain 703 768 7.1E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 Gene3D G3DSA:3.30.565.10 332 489 1.6E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SMART SM00388 265 329 8.9E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SMART SM00304 212 264 1.4E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SUPERFAMILY SSF55874 318 486 7.99E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 Gene3D G3DSA:1.10.287.130 258 324 2.4E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 327 8.5E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SUPERFAMILY SSF47384 248 327 1.33E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 1.7E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 1.7E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 1.7E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 486 7.4E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SUPERFAMILY SSF158472 212 261 5.89E-9 T 06-07-2017 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 Pfam PF00672 HAMP domain 193 261 1.2E-16 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05410 7df6e25fcbb06558e1d9d544f153229c 491 SMART SM00387 375 487 8.0E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04325 b2c82b94d3836eff57599bcbcba03eeb 343 Pfam PF04773 FecR protein 125 220 2.3E-21 T 06-07-2017 IPR006860 FecR protein CAL12_RS04325 b2c82b94d3836eff57599bcbcba03eeb 343 PIRSF PIRSF018266 12 332 1.7E-92 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAL12_RS04325 b2c82b94d3836eff57599bcbcba03eeb 343 Pfam PF16220 Domain of unknown function (DUF4880) 22 64 3.6E-12 T 06-07-2017 IPR032623 FecR, N-terminal CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Gene3D G3DSA:3.30.9.10 229 370 1.7E-13 T 06-07-2017 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Gene3D G3DSA:3.30.9.10 96 149 1.7E-13 T 06-07-2017 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 SUPERFAMILY SSF51905 371 428 2.07E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 SUPERFAMILY SSF51905 18 229 2.07E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Pfam PF01266 FAD dependent oxidoreductase 19 410 1.1E-64 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Gene3D G3DSA:3.50.50.60 6 94 3.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Gene3D G3DSA:3.50.50.60 371 428 3.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS23805 869f8d5b382f02e9849c479984766cb8 430 Gene3D G3DSA:3.50.50.60 150 228 3.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 SUPERFAMILY SSF53850 85 280 3.41E-27 T 06-07-2017 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 Pfam PF03466 LysR substrate binding domain 88 280 3.5E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 Gene3D G3DSA:1.10.10.10 2 85 8.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 Gene3D G3DSA:3.40.190.10 181 229 3.0E-6 T 06-07-2017 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 SUPERFAMILY SSF46785 4 111 2.59E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 Gene3D G3DSA:3.40.190.10 89 176 1.6E-16 T 06-07-2017 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07465 a0bd7782d383508b795c2192aa0d8b29 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.2E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 Gene3D G3DSA:3.40.190.10 103 195 2.2E-16 T 06-07-2017 CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 SUPERFAMILY SSF53850 102 310 1.02E-32 T 06-07-2017 CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 Gene3D G3DSA:3.40.190.10 196 277 9.3E-11 T 06-07-2017 CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 76 2.4E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 Pfam PF03466 LysR substrate binding domain 101 303 2.6E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 Gene3D G3DSA:1.10.10.10 16 98 4.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18145 1b8e59d2f7b22b4d35c9bbbb9cad6f88 320 SUPERFAMILY SSF46785 14 124 1.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 PRINTS PR00605 Class IC cytochrome C signature 333 344 1.8E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 PRINTS PR00605 Class IC cytochrome C signature 386 408 1.8E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 SUPERFAMILY SSF46626 184 297 1.01E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Gene3D G3DSA:1.10.760.10 326 432 5.3E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Pfam PF00034 Cytochrome c 189 298 4.3E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Pfam PF00034 Cytochrome c 327 411 6.6E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Pfam PF00034 Cytochrome c 34 131 3.9E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 PIRSF PIRSF000018 1 438 7.1E-154 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Gene3D G3DSA:1.10.760.10 29 131 1.6E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 Gene3D G3DSA:1.10.760.10 184 297 6.1E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 SUPERFAMILY SSF46626 326 429 7.59E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14285 958eadc6b3fc35d14f5d965b3e0f60ae 439 SUPERFAMILY SSF46626 18 155 5.62E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS12735 682f1eec961821f2bcd214b7b83bfce7 401 SUPERFAMILY SSF103501 180 393 3.79E-33 T 06-07-2017 IPR023234 NarG-like domain CAL12_RS12735 682f1eec961821f2bcd214b7b83bfce7 401 SUPERFAMILY SSF54862 38 100 9.21E-6 T 06-07-2017 CAL12_RS12735 682f1eec961821f2bcd214b7b83bfce7 401 Gene3D G3DSA:3.30.70.20 28 96 4.6E-5 T 06-07-2017 CAL12_RS12735 682f1eec961821f2bcd214b7b83bfce7 401 TIGRFAM TIGR02484 CitB: CitB domain protein 37 395 5.3E-127 T 06-07-2017 IPR012830 Citrate utilization protein B CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 298 718 4.3E-147 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 16 880 5.5E-159 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 Pfam PF14579 Helix-hairpin-helix motif 794 887 6.3E-22 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 SMART SM00481 15 82 3.3E-4 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 14 1056 13.796 T 06-07-2017 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 Pfam PF02811 PHP domain 20 113 2.7E-13 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAL12_RS10235 4c850e7495d0b7167a5628cd58a5f12b 1056 Gene3D G3DSA:3.20.20.140 21 85 4.3E-4 T 06-07-2017 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 41 55 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 PIRSF PIRSF001461 9 237 1.4E-101 T 06-07-2017 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 Pfam PF00834 Ribulose-phosphate 3 epimerase family 14 214 3.4E-88 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 SUPERFAMILY SSF51366 12 229 1.18E-71 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 Gene3D G3DSA:3.20.20.70 12 232 2.7E-91 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 143 165 - T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS26095 80b418c9228be337a29ddbf18d082b26 238 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 14 227 6.4E-95 T 06-07-2017 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS13780 36dc36ef33888af0e754ef93ad0a43ef 339 Pfam PF13343 Bacterial extracellular solute-binding protein 70 297 3.6E-28 T 06-07-2017 CAL12_RS13780 36dc36ef33888af0e754ef93ad0a43ef 339 Gene3D G3DSA:3.40.190.10 124 261 1.5E-33 T 06-07-2017 CAL12_RS13780 36dc36ef33888af0e754ef93ad0a43ef 339 SUPERFAMILY SSF53850 19 334 8.51E-59 T 06-07-2017 CAL12_RS13780 36dc36ef33888af0e754ef93ad0a43ef 339 Gene3D G3DSA:3.40.190.10 262 301 1.5E-10 T 06-07-2017 CAL12_RS13780 36dc36ef33888af0e754ef93ad0a43ef 339 Gene3D G3DSA:3.40.190.10 12 122 1.5E-10 T 06-07-2017 CAL12_RS12210 ab2549ce383cde81021855d84d4ac9b0 246 SUPERFAMILY SSF52317 28 206 4.3E-40 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS12210 ab2549ce383cde81021855d84d4ac9b0 246 Pfam PF00117 Glutamine amidotransferase class-I 41 191 2.8E-19 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS12210 ab2549ce383cde81021855d84d4ac9b0 246 Gene3D G3DSA:3.40.50.880 10 233 6.5E-50 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 Gene3D G3DSA:1.10.10.10 9 59 1.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 SUPERFAMILY SSF46785 10 69 2.58E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 SMART SM00344 10 119 1.5E-38 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 Gene3D G3DSA:3.30.70.920 63 147 4.9E-22 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 SUPERFAMILY SSF54909 72 152 4.29E-13 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 Pfam PF01037 Lrp/AsnC ligand binding domain 76 148 1.6E-15 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 7.0E-18 T 06-07-2017 CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 2.1E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 2.1E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS01075 c847077752a09e395142860dcc468f1e 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 2.1E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 SMART SM00345 45 103 3.9E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 SMART SM00895 113 236 3.4E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 Pfam PF07729 FCD domain 114 235 2.2E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 Gene3D G3DSA:1.20.120.530 106 241 1.0E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 43 103 5.8E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 Gene3D G3DSA:1.10.10.10 39 104 8.0E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 SUPERFAMILY SSF48008 108 241 2.51E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01540 23b7b9e192b0e9b907fa8f6e513815d5 259 SUPERFAMILY SSF46785 43 131 1.06E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16620 6dcf887520d5b683c184342b7fc24533 224 Pfam PF00578 AhpC/TSA family 51 196 3.5E-29 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS16620 6dcf887520d5b683c184342b7fc24533 224 SUPERFAMILY SSF52833 47 218 8.65E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS16620 6dcf887520d5b683c184342b7fc24533 224 Gene3D G3DSA:3.40.30.10 45 219 6.4E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 SUPERFAMILY SSF63411 266 450 2.23E-27 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Pfam PF05193 Peptidase M16 inactive domain 664 838 3.7E-25 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Pfam PF05193 Peptidase M16 inactive domain 206 380 4.0E-29 T 06-07-2017 IPR007863 Peptidase M16, C-terminal CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Pfam PF00675 Insulinase (Peptidase family M16) 51 197 5.3E-20 T 06-07-2017 IPR011765 Peptidase M16, N-terminal CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 SUPERFAMILY SSF63411 742 912 8.13E-30 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Gene3D G3DSA:3.30.830.10 748 911 1.0E-24 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Gene3D G3DSA:3.30.830.10 509 691 1.6E-23 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Gene3D G3DSA:3.30.830.10 37 255 3.0E-50 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 SUPERFAMILY SSF63411 40 257 8.83E-53 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 72 95 - T 06-07-2017 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 SUPERFAMILY SSF63411 480 717 2.97E-29 T 06-07-2017 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CAL12_RS21715 a605ca7abb38001a58d861a0d4831c34 914 Gene3D G3DSA:3.30.830.10 256 441 2.5E-14 T 06-07-2017 IPR011237 Peptidase M16 domain GO:0046872 CAL12_RS04095 935d40dc213d821470240d696b575a18 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 20 128 1.8E-17 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS04095 935d40dc213d821470240d696b575a18 380 Gene3D G3DSA:3.30.390.10 1 131 6.3E-36 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS04095 935d40dc213d821470240d696b575a18 380 Gene3D G3DSA:3.20.20.120 132 372 9.8E-69 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS04095 935d40dc213d821470240d696b575a18 380 SUPERFAMILY SSF54826 1 132 7.53E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS04095 935d40dc213d821470240d696b575a18 380 SMART SM00922 148 244 4.3E-24 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS04095 935d40dc213d821470240d696b575a18 380 SUPERFAMILY SSF51604 118 373 1.31E-63 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS04095 935d40dc213d821470240d696b575a18 380 Pfam PF13378 Enolase C-terminal domain-like 151 364 9.1E-55 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 Pfam PF00924 Mechanosensitive ion channel 69 259 4.8E-46 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 Gene3D G3DSA:3.30.70.100 175 258 1.2E-20 T 06-07-2017 CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 SUPERFAMILY SSF82861 20 104 9.02E-17 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 SUPERFAMILY SSF50182 106 172 3.6E-15 T 06-07-2017 IPR010920 LSM domain CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 Gene3D G3DSA:2.30.30.60 121 171 1.1E-13 T 06-07-2017 CAL12_RS07560 a1e735e8527c4f80b48c436d222cfc13 283 SUPERFAMILY SSF82689 173 270 7.45E-23 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.30.56.10 1 38 4.7E-24 T 06-07-2017 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.30.56.10 155 184 4.7E-24 T 06-07-2017 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SUPERFAMILY SSF55681 465 692 1.74E-50 T 06-07-2017 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Pfam PF03483 B3/4 domain 213 385 6.9E-61 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 798 42.649 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SUPERFAMILY SSF56037 196 392 2.88E-67 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SMART SM00874 401 469 2.2E-27 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SUPERFAMILY SSF54991 698 804 5.1E-18 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Pfam PF01588 Putative tRNA binding domain 45 145 1.6E-25 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SMART SM00873 212 385 2.0E-80 T 06-07-2017 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 804 6.6E-220 T 06-07-2017 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SMART SM00896 703 804 5.9E-23 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.30.56.20 401 473 4.5E-25 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SUPERFAMILY SSF46955 403 473 1.56E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Pfam PF03484 tRNA synthetase B5 domain 404 469 3.1E-18 T 06-07-2017 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 SUPERFAMILY SSF50249 38 190 3.92E-49 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.30.70.380 706 804 3.3E-17 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.50.40.10 199 391 1.5E-74 T 06-07-2017 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:2.40.50.140 42 154 2.3E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Gene3D G3DSA:3.30.930.10 489 693 5.3E-61 T 06-07-2017 CAL12_RS09940 a9b1fd44c42328c42afd35d3083c184e 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 703 804 3.8E-21 T 06-07-2017 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 388 2.3E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 SUPERFAMILY SSF56645 36 249 3.14E-62 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 135 147 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 129 2.9E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 SUPERFAMILY SSF47203 236 389 2.74E-48 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 226 1.1E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Gene3D G3DSA:2.40.110.10 132 227 1.4E-34 T 06-07-2017 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Gene3D G3DSA:1.10.540.10 13 130 4.7E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS24995 4f940335c02480fed9bed383ab905855 391 Gene3D G3DSA:1.20.140.10 228 389 2.3E-58 T 06-07-2017 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 5.4E-23 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 SUPERFAMILY SSF88659 88 163 1.24E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 Gene3D G3DSA:1.10.1740.10 4 79 5.1E-11 T 06-07-2017 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 SUPERFAMILY SSF88946 6 77 5.1E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 Pfam PF08281 Sigma-70, region 4 111 162 1.8E-17 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 Gene3D G3DSA:1.10.10.10 108 163 8.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02025 82d12431db69980e5c2c7d98b0924c8c 169 Pfam PF04542 Sigma-70 region 2 15 79 4.3E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS08975 5a5b7e1d1d13733b9e1694390e34abd6 679 Pfam PF06202 Amylo-alpha-1,6-glucosidase 301 663 2.1E-106 T 06-07-2017 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25+3.2.1.33|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CAL12_RS08975 5a5b7e1d1d13733b9e1694390e34abd6 679 Pfam PF12439 Glycogen debranching enzyme N terminal 13 231 1.6E-51 T 06-07-2017 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal CAL12_RS08975 5a5b7e1d1d13733b9e1694390e34abd6 679 SUPERFAMILY SSF48208 264 664 1.02E-59 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS08975 5a5b7e1d1d13733b9e1694390e34abd6 679 SUPERFAMILY SSF48208 176 232 1.02E-59 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Pfam PF13549 ATP-grasp domain 474 690 6.3E-44 T 06-07-2017 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 SUPERFAMILY SSF52210 146 293 1.57E-31 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Gene3D G3DSA:3.40.50.720 3 131 3.1E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Pfam PF13380 CoA binding domain 13 135 1.6E-20 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Gene3D G3DSA:3.40.50.261 132 289 3.5E-22 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 SUPERFAMILY SSF56059 478 691 2.33E-31 T 06-07-2017 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 SUPERFAMILY SSF52210 308 457 1.96E-24 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 SUPERFAMILY SSF51735 5 133 3.48E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Gene3D G3DSA:3.30.470.20 480 587 6.6E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 SMART SM00881 8 103 1.0E-30 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS20520 0874ead6fdfadf127910e897774e6166 692 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 293 1.9E-36 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS10685 141b0534ef10e105bc6ab7c09266862a 119 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 32 71 4.4E-6 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS10685 141b0534ef10e105bc6ab7c09266862a 119 Gene3D G3DSA:3.40.1620.10 36 63 1.1E-4 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS10685 141b0534ef10e105bc6ab7c09266862a 119 SUPERFAMILY SSF143120 17 68 6.67E-6 T 06-07-2017 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 PRINTS PR01415 Ankyrin repeat signature 126 141 5.4E-7 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 PRINTS PR01415 Ankyrin repeat signature 174 188 5.4E-7 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 Pfam PF12796 Ankyrin repeats (3 copies) 126 189 9.2E-14 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 Pfam PF12796 Ankyrin repeats (3 copies) 44 124 2.9E-6 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 SMART SM00248 95 124 0.095 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 SMART SM00248 125 154 3.9E-6 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 SMART SM00248 158 187 0.018 T 06-07-2017 IPR002110 Ankyrin repeat GO:0005515 CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 SUPERFAMILY SSF48403 39 213 2.24E-37 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAL12_RS15490 95b8df75121a868594ded63a79e8fb39 289 Gene3D G3DSA:1.25.40.20 38 215 9.1E-41 T 06-07-2017 IPR020683 Ankyrin repeat-containing domain CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 Gene3D G3DSA:1.10.760.10 83 159 9.5E-30 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 Gene3D G3DSA:1.10.760.10 227 301 4.2E-30 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 PRINTS PR00607 Class IE cytochrome C signature 235 246 3.0E-14 T 06-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 PRINTS PR00607 Class IE cytochrome C signature 246 256 3.0E-14 T 06-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 PRINTS PR00607 Class IE cytochrome C signature 274 286 3.0E-14 T 06-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 PRINTS PR00607 Class IE cytochrome C signature 289 300 3.0E-14 T 06-07-2017 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 227 299 2.4E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 83 156 5.7E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 SUPERFAMILY SSF46626 66 163 1.06E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS25440 d2d96f3b824473e4a1a0805f8d114172 304 SUPERFAMILY SSF46626 227 301 1.89E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 Pfam PF02501 Type II secretion system (T2SS), protein I 44 118 4.6E-14 T 06-07-2017 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 TIGRFAM TIGR01707 gspI: type II secretion system protein I 9 106 4.8E-14 T 06-07-2017 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 Gene3D G3DSA:3.30.1300.30 37 117 2.8E-5 T 06-07-2017 CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 SUPERFAMILY SSF54523 43 110 2.55E-9 T 06-07-2017 CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 27 5.8E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27320 49e12b5f52770c6a3192b20de7947950 123 Pfam PF13633 Prokaryotic N-terminal methylation site 7 32 2.6E-10 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 SUPERFAMILY SSF100950 158 238 1.04E-24 T 06-07-2017 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 SUPERFAMILY SSF100950 76 131 1.04E-24 T 06-07-2017 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 Gene3D G3DSA:1.10.10.10 1 57 6.1E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 4.4E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 4.4E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 SMART SM00420 6 58 1.4E-9 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 Gene3D G3DSA:3.40.50.1360 76 218 1.4E-10 T 06-07-2017 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 SUPERFAMILY SSF46785 4 74 2.73E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 SMART SM01134 72 239 5.8E-56 T 06-07-2017 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 4.2E-13 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 Pfam PF00455 DeoR C terminal sensor domain 75 237 1.0E-39 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain CAL12_RS11185 d85eb8aa40986b45ef3473a45e77bb20 261 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAL12_RS11455 d108a12365ca4336ef0c241894d8ee59 530 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 58 456 2.2E-86 T 06-07-2017 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 CAL12_RS11455 d108a12365ca4336ef0c241894d8ee59 530 SUPERFAMILY SSF56954 59 458 2.22E-77 T 06-07-2017 CAL12_RS11455 d108a12365ca4336ef0c241894d8ee59 530 Gene3D G3DSA:1.20.1600.10 46 446 3.7E-60 T 06-07-2017 CAL12_RS11455 d108a12365ca4336ef0c241894d8ee59 530 Pfam PF02321 Outer membrane efflux protein 275 450 6.3E-26 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS11455 d108a12365ca4336ef0c241894d8ee59 530 Pfam PF02321 Outer membrane efflux protein 60 247 8.3E-21 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS26535 855c68656cafe8d8ec146998d992ba87 213 SUPERFAMILY SSF52833 16 207 3.08E-38 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26535 855c68656cafe8d8ec146998d992ba87 213 Gene3D G3DSA:3.40.30.10 13 204 1.3E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26535 855c68656cafe8d8ec146998d992ba87 213 Pfam PF01323 DSBA-like thioredoxin domain 17 202 1.1E-35 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAL12_RS26535 855c68656cafe8d8ec146998d992ba87 213 PIRSF PIRSF006386 11 210 1.5E-56 T 06-07-2017 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 SUPERFAMILY SSF52210 239 385 1.31E-54 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 5.9E-159 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Gene3D G3DSA:3.30.1490.20 22 95 1.9E-35 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 SUPERFAMILY SSF56059 1 238 2.83E-82 T 06-07-2017 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 41.704 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Gene3D G3DSA:3.40.50.261 241 383 6.2E-65 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Pfam PF08442 ATP-grasp domain 2 201 2.1E-79 T 06-07-2017 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 PIRSF PIRSF001554 1 386 4.7E-151 T 06-07-2017 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Pfam PF00549 CoA-ligase 262 382 1.3E-25 T 06-07-2017 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 Gene3D G3DSA:3.30.470.20 96 239 6.6E-57 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS09500 7a0021741cd225a709a618f3e4dd6d76 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 06-07-2017 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS05680 a2fe1bad831dd94dd4ffd9db2baa414d 504 Pfam PF01435 Peptidase family M48 78 269 3.8E-33 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAL12_RS05680 a2fe1bad831dd94dd4ffd9db2baa414d 504 SUPERFAMILY SSF48452 321 461 1.14E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS05680 a2fe1bad831dd94dd4ffd9db2baa414d 504 Gene3D G3DSA:3.30.2010.10 74 157 2.6E-20 T 06-07-2017 CAL12_RS05680 a2fe1bad831dd94dd4ffd9db2baa414d 504 Gene3D G3DSA:1.25.40.10 183 200 1.3E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS05680 a2fe1bad831dd94dd4ffd9db2baa414d 504 Gene3D G3DSA:1.25.40.10 320 474 1.3E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF56003 229 268 1.05E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF56003 316 468 1.05E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF56003 561 596 1.23E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 951 1033 3.1E-12 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Pfam PF00034 Cytochrome c 650 749 1.2E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:1.10.760.10 792 899 2.0E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:1.10.760.10 648 749 1.2E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF46626 929 1044 3.78E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF46626 645 772 6.3E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 SUPERFAMILY SSF46626 778 902 1.36E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:1.10.760.10 948 1038 1.7E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:3.30.365.10 561 595 4.3E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:3.30.365.10 350 381 1.9E-7 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01145 93d4856e2a68fce8c794095b2f788e71 1061 Gene3D G3DSA:3.30.365.10 424 470 1.9E-7 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 Gene3D G3DSA:3.20.20.70 1 335 3.5E-112 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 327 2.5E-96 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 9.7E-190 T 06-07-2017 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 PIRSF PIRSF001359 1 329 5.6E-87 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 1.8E-102 T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 SUPERFAMILY SSF51569 1 328 1.14E-107 T 06-07-2017 CAL12_RS05210 1fa045c506be2cd5a14cd4b2dca12ee3 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 06-07-2017 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 SUPERFAMILY SSF53383 8 414 5.98E-103 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 4 415 8.9E-194 T 06-07-2017 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 Gene3D G3DSA:3.40.640.10 65 313 4.8E-63 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 Pfam PF00202 Aminotransferase class-III 21 412 6.8E-75 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 Gene3D G3DSA:3.90.1150.10 10 56 2.9E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 Gene3D G3DSA:3.90.1150.10 319 415 2.9E-27 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 421 7.9E-143 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAL12_RS09095 ea47495b0ebaf271f771cd4e24285da3 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 Gene3D G3DSA:3.40.50.720 1 105 1.1E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 Gene3D G3DSA:3.40.50.720 106 285 9.6E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 284 2.9E-57 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 SUPERFAMILY SSF51735 97 285 4.3E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 309 1.8E-24 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 SUPERFAMILY SSF52283 1 131 5.86E-30 T 06-07-2017 CAL12_RS19025 af0d64b010f34d6c184a553b4ceb65a8 317 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS26595 11b839eb18f5b36ec54c4c7355427280 266 Gene3D G3DSA:3.90.260.10 163 249 4.6E-10 T 06-07-2017 IPR002931 Transglutaminase-like CAL12_RS26595 11b839eb18f5b36ec54c4c7355427280 266 SUPERFAMILY SSF54001 7 247 1.25E-38 T 06-07-2017 CAL12_RS26595 11b839eb18f5b36ec54c4c7355427280 266 Pfam PF01841 Transglutaminase-like superfamily 129 217 1.4E-25 T 06-07-2017 IPR002931 Transglutaminase-like CAL12_RS26595 11b839eb18f5b36ec54c4c7355427280 266 SMART SM00460 158 220 5.9E-20 T 06-07-2017 IPR002931 Transglutaminase-like CAL12_RS26595 11b839eb18f5b36ec54c4c7355427280 266 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 79 3.4E-18 T 06-07-2017 IPR013589 Bacterial transglutaminase-like, N-terminal CAL12_RS24610 3c0ee2fdde9d7f1a2e144b625842538c 213 Pfam PF01323 DSBA-like thioredoxin domain 6 206 6.5E-37 T 06-07-2017 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CAL12_RS24610 3c0ee2fdde9d7f1a2e144b625842538c 213 Gene3D G3DSA:3.40.30.10 3 209 6.0E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS24610 3c0ee2fdde9d7f1a2e144b625842538c 213 SUPERFAMILY SSF52833 2 212 1.29E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Gene3D G3DSA:2.40.50.140 612 724 1.2E-41 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF47323 610 633 2.62E-25 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF47323 396 581 2.62E-25 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Gene3D G3DSA:3.40.50.620 4 141 4.1E-80 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Gene3D G3DSA:3.40.50.620 180 388 4.1E-80 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 520 1.0E-145 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF52374 4 138 7.21E-90 T 06-07-2017 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF52374 173 396 7.21E-90 T 06-07-2017 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Pfam PF01588 Putative tRNA binding domain 625 713 4.8E-22 T 06-07-2017 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 394 405 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 261 272 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 300 315 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 2.3E-22 T 06-07-2017 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 561 36.937 T 06-07-2017 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 609 724 3.1E-40 T 06-07-2017 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF50249 618 724 1.91E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Pfam PF09334 tRNA synthetases class I (M) 6 406 2.7E-136 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 SUPERFAMILY SSF57770 139 173 2.88E-12 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Gene3D G3DSA:1.10.730.10 389 547 1.2E-32 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS02595 e55be85f15d8c65a611a409e86c9294c 725 Gene3D G3DSA:2.20.28.20 142 173 3.4E-18 T 06-07-2017 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 SUPERFAMILY SSF51690 117 387 2.55E-89 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 390 46.354 T 06-07-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 SUPERFAMILY SSF54675 1 136 4.12E-45 T 06-07-2017 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 Gene3D G3DSA:3.20.140.10 1 372 2.8E-144 T 06-07-2017 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 388 2.3E-71 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 PIRSF PIRSF000484 1 376 4.3E-71 T 06-07-2017 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CAL12_RS08235 db997270ad57be0915149e3cdc67e950 398 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 389 2.0E-148 T 06-07-2017 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 Gene3D G3DSA:2.30.40.10 27 137 4.9E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 SUPERFAMILY SSF51556 233 517 4.95E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 SUPERFAMILY SSF51556 91 153 4.95E-40 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 SUPERFAMILY SSF51338 523 567 3.7E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 SUPERFAMILY SSF51338 27 92 3.7E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 Pfam PF07969 Amidohydrolase family 80 564 1.1E-119 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS09315 928fba1c3237f0bea26e8289b4be381a 648 Gene3D G3DSA:3.20.20.140 230 510 1.1E-17 T 06-07-2017 CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 Gene3D G3DSA:1.20.1250.20 3 171 3.8E-30 T 06-07-2017 CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 Pfam PF07690 Major Facilitator Superfamily 5 394 1.6E-55 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 SUPERFAMILY SSF103473 232 440 4.32E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 SUPERFAMILY SSF103473 2 173 4.32E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 1 412 6.4E-87 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS06095 753eacc600f73e1aa24162d81a9f3fae 444 Gene3D G3DSA:1.20.1250.20 247 439 1.4E-17 T 06-07-2017 CAL12_RS11515 7a182118c3d1ca087ebd7712a1cbfe06 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 37 131 4.6E-29 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11515 7a182118c3d1ca087ebd7712a1cbfe06 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2 29 7.5E-5 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 SUPERFAMILY SSF51905 1 55 4.27E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 SUPERFAMILY SSF51905 366 405 4.27E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 SUPERFAMILY SSF51905 106 273 4.27E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Gene3D G3DSA:3.40.50.720 190 271 2.6E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Gene3D G3DSA:3.40.50.720 3 97 2.6E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Gene3D G3DSA:3.40.50.720 360 405 2.6E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 SUPERFAMILY SSF54373 273 366 1.57E-12 T 06-07-2017 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Gene3D G3DSA:3.30.9.10 134 189 1.3E-8 T 06-07-2017 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Gene3D G3DSA:3.30.9.10 272 359 1.3E-8 T 06-07-2017 CAL12_RS25165 ffc8275bb9a6cbc4f7a43e030b89efcb 409 Pfam PF01266 FAD dependent oxidoreductase 4 403 1.3E-62 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS08985 3bd7179275796721236de498fba5f0da 208 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 198 1.2E-16 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS08985 3bd7179275796721236de498fba5f0da 208 SUPERFAMILY SSF88697 4 198 1.24E-46 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS08985 3bd7179275796721236de498fba5f0da 208 SMART SM00464 3 199 2.0E-6 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 SMART SM00382 340 541 7.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 SMART SM00382 30 235 4.6E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Pfam PF00005 ABC transporter 332 482 7.7E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Pfam PF00005 ABC transporter 22 185 2.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 533 582 4.4E-11 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Gene3D G3DSA:3.40.50.300 303 557 4.4E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Gene3D G3DSA:3.40.50.300 2 259 1.1E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 SUPERFAMILY SSF52540 1 257 1.47E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 535 581 1.9E-8 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 266 9.6E-8 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24670 81edc7421207e93c78dd92b1ee17b58c 606 SUPERFAMILY SSF52540 304 555 1.88E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Pfam PF00501 AMP-binding enzyme 10 423 1.9E-75 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Gene3D G3DSA:3.40.50.980 6 172 1.2E-27 T 06-07-2017 CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 509 3.3E-19 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Gene3D G3DSA:2.30.38.10 337 416 3.5E-18 T 06-07-2017 CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Gene3D G3DSA:3.30.300.30 418 517 9.2E-31 T 06-07-2017 CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 Gene3D G3DSA:3.40.50.980 173 326 2.3E-31 T 06-07-2017 CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS15825 9ee5e2ccd0b33f9b7eb9fa0d8982c5b8 542 SUPERFAMILY SSF56801 6 519 4.84E-123 T 06-07-2017 CAL12_RS26390 ec2b41e14859bc1b3045d20a0fd2bfbc 302 Gene3D G3DSA:3.20.20.70 5 291 6.7E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS26390 ec2b41e14859bc1b3045d20a0fd2bfbc 302 Pfam PF00682 HMGL-like 6 278 5.9E-55 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAL12_RS26390 ec2b41e14859bc1b3045d20a0fd2bfbc 302 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 06-07-2017 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111 CAL12_RS26390 ec2b41e14859bc1b3045d20a0fd2bfbc 302 SUPERFAMILY SSF51569 3 287 1.13E-73 T 06-07-2017 CAL12_RS20180 8592b877db0bb80fb12505a37839c8bb 346 SUPERFAMILY SSF54523 194 345 2.09E-12 T 06-07-2017 CAL12_RS20180 8592b877db0bb80fb12505a37839c8bb 346 Pfam PF08805 PilS N terminal 260 345 1.5E-8 T 06-07-2017 IPR014911 Type 4 secretion system, PilS, N-terminal CAL12_RS20180 8592b877db0bb80fb12505a37839c8bb 346 Gene3D G3DSA:3.30.1690.10 259 336 9.7E-5 T 06-07-2017 CAL12_RS08285 a99bd4356b2f5b9dc6f4069ec921a1a6 77 SUPERFAMILY SSF55331 2 65 9.46E-7 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS08285 a99bd4356b2f5b9dc6f4069ec921a1a6 77 Gene3D G3DSA:3.30.429.20 1 60 6.4E-6 T 06-07-2017 CAL12_RS08285 a99bd4356b2f5b9dc6f4069ec921a1a6 77 Pfam PF01361 Tautomerase enzyme 2 60 1.3E-11 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Pfam PF00912 Transglycosylase 77 250 7.3E-62 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 SUPERFAMILY SSF53955 63 272 1.01E-73 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Gene3D G3DSA:1.10.3810.10 77 253 4.5E-72 T 06-07-2017 CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Gene3D G3DSA:2.40.50.140 376 446 8.7E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 86 737 1.5E-176 T 06-07-2017 CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Pfam PF17092 Penicillin-binding protein OB-like domain 341 450 5.6E-16 T 06-07-2017 IPR031376 Penicillin-binding protein, OB-like domain CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Pfam PF00905 Penicillin binding protein transpeptidase domain 453 726 1.6E-37 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 SUPERFAMILY SSF56601 447 755 9.22E-116 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 SUPERFAMILY SSF56601 232 254 9.22E-116 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 SUPERFAMILY SSF56601 287 338 9.22E-116 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Gene3D G3DSA:3.40.710.10 447 750 4.3E-122 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS27435 d1db96ce28e86f48f4b6923c8fefda4c 811 Gene3D G3DSA:3.40.710.10 254 338 4.3E-122 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS24820 9676c91cb5f0781b29c29b4b91cfb2b2 310 Gene3D G3DSA:3.40.190.10 160 215 8.2E-4 T 06-07-2017 CAL12_RS24820 9676c91cb5f0781b29c29b4b91cfb2b2 310 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 37 306 5.3E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24820 9676c91cb5f0781b29c29b4b91cfb2b2 310 PIRSF PIRSF017082 1 310 4.7E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24820 9676c91cb5f0781b29c29b4b91cfb2b2 310 SUPERFAMILY SSF53850 101 270 9.28E-12 T 06-07-2017 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 Gene3D G3DSA:3.30.499.10 275 419 3.5E-47 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 SUPERFAMILY SSF53732 2 420 1.19E-121 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 Gene3D G3DSA:3.30.499.10 2 161 5.0E-32 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 354 367 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 116 129 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 130 145 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 192 205 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 105 113 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 PRINTS PR00415 Aconitase family signature 206 219 2.6E-11 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 Pfam PF00330 Aconitase family (aconitate hydratase) 7 413 8.5E-78 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 419 5.8E-135 T 06-07-2017 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 418 6.1E-147 T 06-07-2017 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 421 42.897 T 06-07-2017 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS13615 5f12af176b74d649596a5b08a5b199f3 421 Gene3D G3DSA:3.40.1060.10 163 267 6.2E-28 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21600 350647e917c47d12649be91198c25d13 230 SMART SM00448 6 116 1.6E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21600 350647e917c47d12649be91198c25d13 230 Gene3D G3DSA:3.40.50.2300 6 124 6.6E-34 T 06-07-2017 CAL12_RS21600 350647e917c47d12649be91198c25d13 230 Gene3D G3DSA:1.10.10.10 132 229 8.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21600 350647e917c47d12649be91198c25d13 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 5.7E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS21600 350647e917c47d12649be91198c25d13 230 Pfam PF00072 Response regulator receiver domain 8 116 2.8E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21600 350647e917c47d12649be91198c25d13 230 SUPERFAMILY SSF52172 6 186 2.05E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS21600 350647e917c47d12649be91198c25d13 230 SMART SM00862 152 228 5.2E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Gene3D G3DSA:3.30.300.30 473 574 1.7E-32 T 06-07-2017 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Gene3D G3DSA:3.40.50.980 232 382 1.6E-39 T 06-07-2017 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 SUPERFAMILY SSF56801 62 576 3.66E-149 T 06-07-2017 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 ProSitePatterns PS00455 Putative AMP-binding domain signature. 226 237 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Gene3D G3DSA:3.40.50.980 68 231 1.9E-35 T 06-07-2017 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Gene3D G3DSA:2.30.38.10 397 469 2.9E-25 T 06-07-2017 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Pfam PF00501 AMP-binding enzyme 73 478 1.0E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS24565 4bb59c76f5708dfa6a9194639fa489f5 581 Pfam PF13193 AMP-binding enzyme C-terminal domain 487 557 9.1E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS18335 647f8b1ccbb0bda720e223a3fdf9ded6 293 SUPERFAMILY SSF103481 37 136 1.7E-12 T 06-07-2017 CAL12_RS18335 647f8b1ccbb0bda720e223a3fdf9ded6 293 Pfam PF00892 EamA-like transporter family 143 273 4.3E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS18335 647f8b1ccbb0bda720e223a3fdf9ded6 293 Pfam PF00892 EamA-like transporter family 3 132 8.1E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS18335 647f8b1ccbb0bda720e223a3fdf9ded6 293 SUPERFAMILY SSF103481 203 279 1.06E-10 T 06-07-2017 CAL12_RS12900 2597588ad6cd5cb3fefcecc2fe27597b 555 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 514 1.2E-115 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS03835 2597588ad6cd5cb3fefcecc2fe27597b 555 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 514 1.2E-115 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 SUPERFAMILY SSF46785 10 91 1.15E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 Pfam PF03466 LysR substrate binding domain 104 289 9.3E-14 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 Gene3D G3DSA:3.40.190.10 103 173 9.9E-11 T 06-07-2017 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 Gene3D G3DSA:3.40.190.10 174 256 2.5E-15 T 06-07-2017 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 SUPERFAMILY SSF53850 103 292 1.17E-18 T 06-07-2017 CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 Gene3D G3DSA:1.10.10.10 9 90 5.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07205 6c03e2bdfd705790a37b1b75fe8fe927 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 8.4E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SUPERFAMILY SSF52821 122 247 4.85E-27 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Gene3D G3DSA:3.40.250.10 276 363 1.5E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Gene3D G3DSA:3.40.250.10 8 125 1.4E-22 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Gene3D G3DSA:3.40.250.10 409 519 5.8E-13 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SUPERFAMILY SSF52821 414 565 1.26E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SMART SM00450 146 244 0.0019 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SMART SM00450 282 378 7.6E-4 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SMART SM00450 417 514 0.057 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SMART SM00450 23 120 1.2E-14 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Gene3D G3DSA:3.40.250.10 142 248 5.8E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SUPERFAMILY SSF52821 274 365 1.57E-20 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 SUPERFAMILY SSF52821 19 136 2.36E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Pfam PF00581 Rhodanese-like domain 23 116 4.4E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Pfam PF00581 Rhodanese-like domain 148 240 9.8E-6 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS10625 1e212e2f416b1466ac79944ba2b092ea 578 Pfam PF00581 Rhodanese-like domain 285 356 4.5E-6 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07955 e6608f28c63b7ce75bcfb9ffc6fc3fa9 415 SUPERFAMILY SSF53756 2 402 7.49E-53 T 06-07-2017 CAL12_RS07955 e6608f28c63b7ce75bcfb9ffc6fc3fa9 415 Pfam PF13692 Glycosyl transferases group 1 229 367 1.5E-14 T 06-07-2017 CAL12_RS07955 e6608f28c63b7ce75bcfb9ffc6fc3fa9 415 Pfam PF13579 Glycosyl transferase 4-like domain 15 202 2.9E-28 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS07955 e6608f28c63b7ce75bcfb9ffc6fc3fa9 415 Gene3D G3DSA:3.40.50.2000 216 381 6.1E-10 T 06-07-2017 CAL12_RS10100 3fb4d81e43595ce669594334accc3851 637 Gene3D G3DSA:3.40.50.1820 343 636 2.1E-94 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10100 3fb4d81e43595ce669594334accc3851 637 SUPERFAMILY SSF82171 43 377 3.53E-15 T 06-07-2017 CAL12_RS10100 3fb4d81e43595ce669594334accc3851 637 Pfam PF00326 Prolyl oligopeptidase family 424 636 3.9E-49 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAL12_RS10100 3fb4d81e43595ce669594334accc3851 637 SUPERFAMILY SSF53474 379 636 3.13E-73 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10100 3fb4d81e43595ce669594334accc3851 637 Gene3D G3DSA:2.120.10.30 41 267 3.4E-14 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 Pfam PF07475 HPr Serine kinase C-terminal domain 129 299 2.0E-64 T 06-07-2017 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 Gene3D G3DSA:3.40.1390.20 7 131 7.4E-30 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 SUPERFAMILY SSF53795 132 298 8.24E-36 T 06-07-2017 CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 Pfam PF02603 HPr Serine kinase N terminus 3 127 3.6E-23 T 06-07-2017 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 SUPERFAMILY SSF75138 7 131 3.53E-29 T 06-07-2017 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 4.4E-98 T 06-07-2017 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 Gene3D G3DSA:3.40.50.300 133 305 2.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01705 169f6bc93c95d6310838e9b1fa6270ae 308 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 306 37.511 T 06-07-2017 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 Pfam PF07687 Peptidase dimerisation domain 203 352 9.8E-5 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 SUPERFAMILY SSF53187 369 455 3.14E-46 T 06-07-2017 CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 SUPERFAMILY SSF53187 18 203 3.14E-46 T 06-07-2017 CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 Pfam PF01546 Peptidase family M20/M25/M40 90 450 4.4E-20 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 Gene3D G3DSA:3.30.70.360 213 363 1.7E-33 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 Gene3D G3DSA:3.40.630.10 19 212 5.1E-45 T 06-07-2017 CAL12_RS23775 1cd2f36fda0a4494c32d17d5f5a5835e 465 Gene3D G3DSA:3.40.630.10 394 455 5.1E-45 T 06-07-2017 CAL12_RS08185 e02c5405339931ec3966fc40310f4455 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 302 7.0E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 SUPERFAMILY SSF56235 7 534 2.89E-174 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 446 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 256 275 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 243 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 6.7E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS22575 d5d5b25420a85cfc6b8955bc5c8cd131 534 Pfam PF01019 Gamma-glutamyltranspeptidase 35 529 5.5E-152 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS10810 cb3e7baf8d2c6846e415130f3daebc86 216 Gene3D G3DSA:1.10.3720.10 11 213 3.1E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10810 cb3e7baf8d2c6846e415130f3daebc86 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 2.3E-26 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS10810 cb3e7baf8d2c6846e415130f3daebc86 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 213 1.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10810 cb3e7baf8d2c6846e415130f3daebc86 216 SUPERFAMILY SSF161098 13 198 9.68E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13575 65b3f61f2c8be6ac2dc273a517fa855f 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 314 3.2E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13575 65b3f61f2c8be6ac2dc273a517fa855f 321 SUPERFAMILY SSF53850 109 279 3.26E-14 T 06-07-2017 CAL12_RS13575 65b3f61f2c8be6ac2dc273a517fa855f 321 PIRSF PIRSF017082 1 320 4.0E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 Pfam PF09423 PhoD-like phosphatase 164 642 7.6E-87 T 06-07-2017 IPR018946 Alkaline phosphatase D-related CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 62 151 1.1E-28 T 06-07-2017 IPR032093 Phospholipase D, N-terminal CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 SUPERFAMILY SSF56300 389 411 5.52E-20 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 SUPERFAMILY SSF56300 236 348 5.52E-20 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 SUPERFAMILY SSF56300 161 203 5.52E-20 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 SUPERFAMILY SSF56300 510 549 5.52E-20 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 Gene3D G3DSA:3.60.21.10 233 408 7.2E-9 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18845 da1c266f7fc7df02f47437cb101d2858 678 Gene3D G3DSA:3.60.21.10 175 201 7.2E-9 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 Pfam PF00005 ABC transporter 24 168 6.7E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 SUPERFAMILY SSF52540 16 230 1.74E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 SUPERFAMILY SSF50331 247 367 8.88E-18 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 Pfam PF03459 TOBE domain 304 366 3.9E-15 T 06-07-2017 IPR005116 Transport-associated OB, type 1 CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 SMART SM00382 31 218 4.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 Gene3D G3DSA:3.40.50.300 24 233 5.2E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 10 365 8.5E-138 T 06-07-2017 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 CAL12_RS12650 c7cc57159cb4fc823cbdffc38b2050f0 367 Gene3D G3DSA:2.40.50.100 290 363 4.5E-16 T 06-07-2017 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 14 102 2.2E-19 T 06-07-2017 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 SUPERFAMILY SSF51445 144 478 2.96E-138 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 SUPERFAMILY SSF51445 507 584 2.96E-138 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 Gene3D G3DSA:3.20.20.80 161 584 1.3E-125 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 SUPERFAMILY SSF81296 10 152 2.72E-49 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 Gene3D G3DSA:2.60.40.10 9 160 2.8E-55 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 10 703 0.0 T 06-07-2017 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 SUPERFAMILY SSF51011 596 703 3.02E-23 T 06-07-2017 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 SMART SM00642 142 575 3.0E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 Gene3D G3DSA:2.60.40.1180 596 703 1.2E-24 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAL12_RS06935 642efb7644e5d02559b8e8b7e0996ac9 729 Pfam PF00128 Alpha amylase, catalytic domain 186 285 3.8E-9 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 SMART SM00448 9 128 4.1E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 Pfam PF00072 Response regulator receiver domain 11 101 5.8E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 Gene3D G3DSA:3.40.50.2300 10 129 1.3E-16 T 06-07-2017 CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 SUPERFAMILY SSF141868 160 406 1.44E-77 T 06-07-2017 IPR001633 EAL domain CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 Pfam PF00563 EAL domain 160 392 4.5E-68 T 06-07-2017 IPR001633 EAL domain CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 SMART SM00052 153 398 1.2E-86 T 06-07-2017 IPR001633 EAL domain CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 Gene3D G3DSA:3.20.20.450 160 406 7.5E-82 T 06-07-2017 IPR001633 EAL domain CAL12_RS23725 bbcc2a6dc6439611e28b74b53a75b7b8 423 SUPERFAMILY SSF52172 10 129 6.83E-17 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 SUPERFAMILY SSF52540 4 205 2.15E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 PRINTS PR00315 GTP-binding elongation factor signature 7 20 8.6E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 PRINTS PR00315 GTP-binding elongation factor signature 87 98 8.6E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 PRINTS PR00315 GTP-binding elongation factor signature 71 81 8.6E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 PRINTS PR00315 GTP-binding elongation factor signature 51 59 8.6E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 PRINTS PR00315 GTP-binding elongation factor signature 123 132 8.6E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 SUPERFAMILY SSF54980 305 390 2.66E-13 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Pfam PF00679 Elongation factor G C-terminus 400 479 1.3E-21 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Gene3D G3DSA:3.30.70.240 403 481 1.6E-31 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 602 1.3E-283 T 06-07-2017 IPR006298 GTP-binding protein TypA GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 SUPERFAMILY SSF50447 151 295 2.27E-26 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 134 1.1E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 SUPERFAMILY SSF54980 401 516 2.21E-28 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Pfam PF00009 Elongation factor Tu GTP binding domain 5 195 1.5E-54 T 06-07-2017 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Gene3D G3DSA:2.40.50.250 486 580 3.5E-42 T 06-07-2017 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Gene3D G3DSA:2.40.30.10 206 300 2.1E-20 T 06-07-2017 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Pfam PF03144 Elongation factor Tu domain 2 219 289 7.8E-9 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Gene3D G3DSA:3.30.70.870 305 402 3.0E-38 T 06-07-2017 CAL12_RS18415 76c896fb98e46b7585ea08299558553b 608 Gene3D G3DSA:3.40.50.300 4 205 5.4E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16640 4eab952faadd191f5ee2d984226377cd 254 Gene3D G3DSA:1.20.1250.20 144 242 7.1E-7 T 06-07-2017 CAL12_RS16640 4eab952faadd191f5ee2d984226377cd 254 SUPERFAMILY SSF103473 3 253 5.75E-19 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16640 4eab952faadd191f5ee2d984226377cd 254 Gene3D G3DSA:1.20.1250.20 3 120 8.1E-5 T 06-07-2017 CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 6.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.8E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 1.5E-62 T 06-07-2017 CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 Gene3D G3DSA:3.40.50.720 3 246 9.2E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 SUPERFAMILY SSF51735 7 246 4.32E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04515 f78592498acc8998e3cd88f973b30ed8 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 7.8E-5 T 06-07-2017 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 Gene3D G3DSA:1.10.1740.10 3 113 1.9E-27 T 06-07-2017 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 SUPERFAMILY SSF88946 3 98 3.14E-26 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 SUPERFAMILY SSF88659 103 177 5.05E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 79 - T 06-07-2017 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 Gene3D G3DSA:1.10.10.10 115 177 9.8E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 Pfam PF08281 Sigma-70, region 4 120 172 9.1E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 6.6E-31 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04380 197ef298cb835a2ed1aa66603ab82650 188 Pfam PF04542 Sigma-70 region 2 29 91 6.4E-20 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 Gene3D G3DSA:1.10.10.10 4 72 4.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 SUPERFAMILY SSF46785 3 75 5.25E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 69 1.5E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 SUPERFAMILY SSF48008 79 218 4.71E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 Pfam PF07729 FCD domain 83 210 4.5E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 Gene3D G3DSA:1.20.120.530 76 219 1.4E-17 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS06180 4e75246a5270bf5e9315c87e6cfa6593 234 SMART SM00895 81 211 4.9E-9 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS20690 9948cb76bb53b04ce314fa6c1c640786 467 SUPERFAMILY SSF103378 26 461 1.31E-83 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS20690 9948cb76bb53b04ce314fa6c1c640786 467 Pfam PF03972 MmgE/PrpD family 34 450 1.4E-78 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS20690 9948cb76bb53b04ce314fa6c1c640786 467 Gene3D G3DSA:3.30.1330.120 286 406 1.2E-14 T 06-07-2017 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 74 3.4E-4 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 3.5E-35 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 SUPERFAMILY SSF46767 77 158 7.46E-32 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 160 37.036 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 Gene3D G3DSA:1.10.10.10 77 159 1.2E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 SUPERFAMILY SSF53155 5 83 3.14E-17 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS02455 51f3e5ea9566d25d1147ea9c65b84d95 165 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 1.0E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 161 3.0E-40 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 Gene3D G3DSA:3.40.50.720 2 161 3.9E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 275 1.1E-24 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 Gene3D G3DSA:1.10.1040.10 163 286 1.1E-28 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 SUPERFAMILY SSF48179 164 289 4.76E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 PIRSF PIRSF000103 2 290 2.8E-63 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS07900 af60891da7ffe8574c2f386e68db8ff5 296 SUPERFAMILY SSF51735 5 161 2.63E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08995 29b7431d3e1e5c8f01be1a8136d389ba 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 319 1.1E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08995 29b7431d3e1e5c8f01be1a8136d389ba 323 PIRSF PIRSF017082 1 323 4.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08995 29b7431d3e1e5c8f01be1a8136d389ba 323 SUPERFAMILY SSF53850 117 277 9.05E-13 T 06-07-2017 CAL12_RS23870 aafbac9a073883585acbc4ab1619238b 258 SUPERFAMILY SSF56219 1 256 4.06E-81 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS23870 aafbac9a073883585acbc4ab1619238b 258 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 256 1.2E-72 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAL12_RS23870 aafbac9a073883585acbc4ab1619238b 258 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 248 3.8E-20 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS23870 aafbac9a073883585acbc4ab1619238b 258 Gene3D G3DSA:3.60.10.10 1 256 1.0E-82 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS23870 aafbac9a073883585acbc4ab1619238b 258 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 255 2.2E-75 T 06-07-2017 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 25 497 5.6E-207 T 06-07-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 Gene3D G3DSA:3.40.50.1580 188 478 3.3E-113 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 27 181 1.4E-54 T 06-07-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 SUPERFAMILY SSF53167 24 497 6.15E-153 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 Gene3D G3DSA:3.30.1730.10 17 184 1.8E-59 T 06-07-2017 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 Pfam PF01048 Phosphorylase superfamily 284 442 1.6E-12 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS15210 74d3c851e7f2b58a8e2c75f2ced9ebe3 497 Hamap MF_01932 AMP nucleosidase [amn]. 17 497 61.032 T 06-07-2017 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 20 699 1.5E-268 T 06-07-2017 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 Pfam PF00771 FHIPEP family 28 691 4.0E-268 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PIRSF PIRSF005419 6 702 1.7E-245 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 158 176 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 239 253 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 139 155 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 188 205 4.2E-56 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS11865 3e6932038abff54e14fe01b24828757c 704 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 144 167 - T 06-07-2017 IPR025505 FHIPEP conserved site CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 Gene3D G3DSA:3.50.50.60 2 150 2.5E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 SUPERFAMILY SSF55424 352 472 6.53E-42 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 Gene3D G3DSA:3.50.50.60 151 343 3.3E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 SUPERFAMILY SSF51905 1 347 1.54E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 6.8E-77 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PIRSF PIRSF000350 1 474 4.0E-81 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 Gene3D G3DSA:3.30.390.30 344 472 5.6E-49 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 4.0E-161 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 3.5E-40 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 3.5E-40 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-40 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.5E-40 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 3.5E-40 T 06-07-2017 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 465 1.4E-38 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS19215 0b49514b4efb56d89bc3871dda82406b 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 3.0E-67 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01365 0d9619616f4f97fca264489d331e504c 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 290 2.5E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01365 0d9619616f4f97fca264489d331e504c 300 Gene3D G3DSA:1.10.3720.10 26 293 2.9E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01365 0d9619616f4f97fca264489d331e504c 300 SUPERFAMILY SSF161098 24 294 2.88E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24025 dd2c9861b9e0d79f92e0913ecac11263 131 Pfam PF04138 GtrA-like protein 11 125 1.1E-17 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 182 209 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 SUPERFAMILY SSF51735 153 316 5.65E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 Pfam PF00107 Zinc-binding dehydrogenase 189 312 1.7E-23 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 SMART SM00829 8 346 8.1E-6 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 Gene3D G3DSA:3.90.180.10 1 183 8.8E-61 T 06-07-2017 IPR011032 GroES-like CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 SUPERFAMILY SSF50129 12 175 7.76E-48 T 06-07-2017 IPR011032 GroES-like CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 147 1.0E-26 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS19785 a745aa6d570075a04ababe6760a748da 351 Gene3D G3DSA:3.40.50.720 184 296 6.5E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF56784 542 783 5.34E-53 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF56784 488 507 5.34E-53 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF81665 238 291 1.44E-10 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF81665 389 481 1.44E-10 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF55008 94 164 4.07E-8 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Gene3D G3DSA:3.40.1110.10 510 611 7.6E-14 T 06-07-2017 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 707 719 1.4E-23 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 489 503 1.4E-23 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 631 641 1.4E-23 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 1.4E-23 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 683 702 1.4E-23 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 491 497 - T 06-07-2017 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 237 786 2.3E-172 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Gene3D G3DSA:2.70.150.10 237 389 2.8E-28 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 260 767 2.5E-71 T 06-07-2017 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00941 Cadmium-transporting ATPase signature 272 292 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00941 Cadmium-transporting ATPase signature 373 387 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 PRINTS PR00941 Cadmium-transporting ATPase signature 354 370 6.3E-10 T 06-07-2017 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 SUPERFAMILY SSF81653 295 388 5.62E-26 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Gene3D G3DSA:3.40.50.1000 612 752 2.3E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Gene3D G3DSA:3.40.50.1000 463 505 2.3E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Pfam PF00702 haloacid dehalogenase-like hydrolase 486 697 8.6E-34 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 220 786 1.0E-122 T 06-07-2017 CAL12_RS11660 e7fd22bf529b8f508e00c5876c23d4b9 815 Pfam PF00122 E1-E2 ATPase 258 480 2.1E-66 T 06-07-2017 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 Pfam PF02321 Outer membrane efflux protein 85 270 7.6E-24 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 Pfam PF02321 Outer membrane efflux protein 297 481 1.6E-21 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 SUPERFAMILY SSF56954 12 40 9.16E-107 T 06-07-2017 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 SUPERFAMILY SSF56954 76 485 9.16E-107 T 06-07-2017 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 Gene3D G3DSA:1.20.1600.10 76 486 7.4E-106 T 06-07-2017 CAL12_RS23230 4d40aee4b356ea9e659466bf35fe0c3f 503 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 24 483 7.5E-125 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS06490 74dd762eba7ec61db59e031cb40a8064 268 Gene3D G3DSA:3.40.50.300 3 215 6.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06490 74dd762eba7ec61db59e031cb40a8064 268 SMART SM00382 36 216 5.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS06490 74dd762eba7ec61db59e031cb40a8064 268 Pfam PF00005 ABC transporter 29 166 6.3E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS06490 74dd762eba7ec61db59e031cb40a8064 268 SUPERFAMILY SSF52540 8 232 2.38E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06490 74dd762eba7ec61db59e031cb40a8064 268 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS21075 1f51ce54a0e52fea715e150da95f39ac 193 Pfam PF06042 Nucleotidyltransferase 28 186 5.2E-55 T 06-07-2017 IPR009267 Putative nucleotidyltransferase CAL12_RS08680 72b7bb2d53755f55a7aadb2bc85384b9 282 SUPERFAMILY SSF56300 10 127 2.64E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS08680 72b7bb2d53755f55a7aadb2bc85384b9 282 SUPERFAMILY SSF56300 183 247 2.64E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS08680 72b7bb2d53755f55a7aadb2bc85384b9 282 Gene3D G3DSA:3.60.21.10 10 152 2.5E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS08680 72b7bb2d53755f55a7aadb2bc85384b9 282 Gene3D G3DSA:3.60.21.10 193 242 2.5E-31 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS08680 72b7bb2d53755f55a7aadb2bc85384b9 282 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 12 224 8.4E-10 T 06-07-2017 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CAL12_RS08245 54561712c0ea2551585ba20a4d3cd90b 287 Pfam PF06167 Glucose-regulated metallo-peptidase M90 19 269 6.6E-76 T 06-07-2017 IPR010384 MtfA family CAL12_RS08245 54561712c0ea2551585ba20a4d3cd90b 287 SUPERFAMILY SSF55486 48 196 3.66E-35 T 06-07-2017 CAL12_RS08245 54561712c0ea2551585ba20a4d3cd90b 287 SUPERFAMILY SSF55486 228 271 3.66E-35 T 06-07-2017 CAL12_RS08245 54561712c0ea2551585ba20a4d3cd90b 287 Gene3D G3DSA:3.40.390.10 40 270 2.0E-28 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 Gene3D G3DSA:3.40.190.10 178 262 6.1E-19 T 06-07-2017 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 Gene3D G3DSA:3.40.190.10 90 177 8.8E-19 T 06-07-2017 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 SUPERFAMILY SSF53850 90 298 1.15E-40 T 06-07-2017 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 Gene3D G3DSA:1.10.10.10 4 87 2.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 Pfam PF03466 LysR substrate binding domain 89 295 9.6E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 SUPERFAMILY SSF46785 4 86 2.15E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13220 dd7e56d2f0f4cffbc57c95b552ccf6ac 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.9E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12965 3777107198dfefb55f413a1375246d56 357 Gene3D G3DSA:3.40.190.10 114 237 5.1E-15 T 06-07-2017 CAL12_RS12965 3777107198dfefb55f413a1375246d56 357 Pfam PF09084 NMT1/THI5 like 41 253 2.8E-21 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS12965 3777107198dfefb55f413a1375246d56 357 SUPERFAMILY SSF53850 35 262 6.86E-31 T 06-07-2017 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 Pfam PF07687 Peptidase dimerisation domain 200 290 5.7E-9 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 Gene3D G3DSA:3.30.70.360 197 313 1.2E-32 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 SUPERFAMILY SSF53187 15 211 5.99E-70 T 06-07-2017 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 SUPERFAMILY SSF53187 314 417 5.99E-70 T 06-07-2017 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 23 378 4.7E-80 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 PIRSF PIRSF005962 7 419 4.1E-96 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 SUPERFAMILY SSF55031 199 300 4.32E-26 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 Gene3D G3DSA:3.40.630.10 314 420 2.5E-82 T 06-07-2017 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 Gene3D G3DSA:3.40.630.10 17 192 2.5E-82 T 06-07-2017 CAL12_RS15360 4d65a754f75c1130b72a83cda9dc8890 427 Pfam PF01546 Peptidase family M20/M25/M40 76 379 5.6E-22 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 SMART SM00345 13 71 3.5E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 Gene3D G3DSA:1.20.120.530 74 216 9.6E-10 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 Gene3D G3DSA:1.10.10.10 4 71 7.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 SUPERFAMILY SSF48008 78 213 1.8E-8 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 71 1.0E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 Pfam PF07729 FCD domain 81 202 3.2E-8 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS25640 e93e210b653a6346e4646e6bbf8e5fe6 230 SUPERFAMILY SSF46785 4 75 4.77E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 232 1.9E-50 T 06-07-2017 CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 Gene3D G3DSA:3.40.50.720 4 234 8.2E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 SUPERFAMILY SSF51735 2 235 2.55E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18100 33c8669c007abbd60d0b950e9680c44f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.7E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS26235 781e7603274a18a464a7844c51ec217b 311 SUPERFAMILY SSF53335 17 284 1.93E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26235 781e7603274a18a464a7844c51ec217b 311 Gene3D G3DSA:3.40.50.150 37 285 4.0E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26235 781e7603274a18a464a7844c51ec217b 311 Pfam PF08241 Methyltransferase domain 54 168 1.4E-16 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAL12_RS26235 781e7603274a18a464a7844c51ec217b 311 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 10 285 25.119 T 06-07-2017 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519 CAL12_RS16975 a4be0ab00a0dc06e939e4ea7d96115a0 181 Gene3D G3DSA:3.40.50.300 7 128 1.5E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16975 a4be0ab00a0dc06e939e4ea7d96115a0 181 SUPERFAMILY SSF52540 6 177 6.71E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17140 2f5a21c07d73dbb8f083265a5920708e 299 SUPERFAMILY SSF52335 16 141 1.72E-21 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS17140 2f5a21c07d73dbb8f083265a5920708e 299 SUPERFAMILY SSF52335 154 293 5.95E-32 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS17140 2f5a21c07d73dbb8f083265a5920708e 299 ProSitePatterns PS01335 Methylglyoxal synthase active site. 222 230 - T 06-07-2017 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 CAL12_RS17140 2f5a21c07d73dbb8f083265a5920708e 299 Gene3D G3DSA:3.40.50.1380 6 145 2.0E-34 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS17140 2f5a21c07d73dbb8f083265a5920708e 299 Gene3D G3DSA:3.40.50.1380 156 293 1.3E-42 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Gene3D G3DSA:3.30.70.20 824 869 4.5E-14 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 SUPERFAMILY SSF53706 98 487 4.19E-22 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Gene3D G3DSA:3.30.70.20 892 974 8.4E-39 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Gene3D G3DSA:3.30.70.20 757 822 8.4E-39 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Gene3D G3DSA:2.40.40.20 590 675 9.6E-11 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Gene3D G3DSA:3.40.50.740 386 475 4.2E-9 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Pfam PF12838 4Fe-4S dicluster domain 766 834 1.6E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 Pfam PF12838 4Fe-4S dicluster domain 849 936 2.3E-9 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 SUPERFAMILY SSF54862 758 974 9.63E-51 T 06-07-2017 CAL12_RS14930 0262cbe105ad1474e447be5a56f7667b 989 SUPERFAMILY SSF50692 596 681 5.65E-10 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 Gene3D G3DSA:1.10.10.10 1 82 1.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.6E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 Pfam PF03466 LysR substrate binding domain 87 286 2.4E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 Gene3D G3DSA:3.40.190.10 190 259 4.9E-9 T 06-07-2017 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 Gene3D G3DSA:3.40.190.10 83 189 2.2E-20 T 06-07-2017 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 SUPERFAMILY SSF53850 89 290 4.48E-33 T 06-07-2017 CAL12_RS10220 b4aca7aa1dcf68a0dc6a72750764524f 296 SUPERFAMILY SSF46785 1 108 5.78E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 PRINTS PR00116 Arginase signature 233 262 3.7E-13 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 PRINTS PR00116 Arginase signature 121 136 3.7E-13 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 Pfam PF00491 Arginase family 34 305 2.6E-85 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 Gene3D G3DSA:3.40.800.10 9 310 4.2E-111 T 06-07-2017 IPR023696 Ureohydrolase domain CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 SUPERFAMILY SSF52768 13 309 6.48E-95 T 06-07-2017 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 ProSitePatterns PS01053 Arginase family signature. 236 257 - T 06-07-2017 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 TIGRFAM TIGR01230 agmatinase: agmatinase 29 305 3.2E-58 T 06-07-2017 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CAL12_RS25530 c86dc4530959c1078e04eceb987e00fd 316 PIRSF PIRSF036979 12 312 1.5E-92 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS19740 97d5f94233b0baad3b144075fc860ea9 387 SUPERFAMILY SSF50952 35 379 4.32E-44 T 06-07-2017 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CAL12_RS19740 97d5f94233b0baad3b144075fc860ea9 387 Gene3D G3DSA:2.120.10.30 20 384 1.1E-105 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS19740 97d5f94233b0baad3b144075fc860ea9 387 Pfam PF07995 Glucose / Sorbosone dehydrogenase 51 378 1.0E-124 T 06-07-2017 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 SUPERFAMILY SSF52141 32 210 3.92E-62 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 Gene3D G3DSA:3.40.470.10 32 211 2.8E-69 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 SMART SM00987 56 207 1.2E-45 T 06-07-2017 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 SMART SM00986 56 207 1.2E-45 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 Pfam PF03167 Uracil DNA glycosylase superfamily 56 207 1.8E-47 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS19575 63a3e8fa5cdd025a091d0d8faf9b9614 212 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 42 207 2.3E-64 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAL12_RS18295 3a36eab05ef475e09ba0464e3edf2e0c 271 Gene3D G3DSA:3.10.270.10 10 264 4.9E-101 T 06-07-2017 CAL12_RS18295 3a36eab05ef475e09ba0464e3edf2e0c 271 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 11 266 35.917 T 06-07-2017 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 CAL12_RS18295 3a36eab05ef475e09ba0464e3edf2e0c 271 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 23 261 1.7E-29 T 06-07-2017 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 CAL12_RS18295 3a36eab05ef475e09ba0464e3edf2e0c 271 Pfam PF02649 Type I GTP cyclohydrolase folE2 11 261 7.2E-90 T 06-07-2017 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442 CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.2E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.0E-45 T 06-07-2017 CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 SUPERFAMILY SSF51735 6 251 8.23E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16220 328336ff9417f08ff1193a7419f3da61 256 Gene3D G3DSA:3.40.50.720 2 251 2.2E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04680 fdb6b2dec91cc57864597b1b46c7e90e 463 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 262 273 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS04680 fdb6b2dec91cc57864597b1b46c7e90e 463 Pfam PF00171 Aldehyde dehydrogenase family 10 458 1.5E-143 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS04680 fdb6b2dec91cc57864597b1b46c7e90e 463 Gene3D G3DSA:3.40.309.10 248 433 7.0E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS04680 fdb6b2dec91cc57864597b1b46c7e90e 463 Gene3D G3DSA:3.40.605.10 12 247 2.4E-75 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS04680 fdb6b2dec91cc57864597b1b46c7e90e 463 SUPERFAMILY SSF53720 6 461 2.36E-145 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.3E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.3E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 Pfam PF07702 UTRA domain 100 230 4.6E-25 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 SUPERFAMILY SSF64288 61 236 2.04E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS05135 652667333508b63f556240bf916e6a67 244 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 3 237 3.0E-75 T 06-07-2017 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF CAL12_RS05135 652667333508b63f556240bf916e6a67 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 1.1E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 Gene3D G3DSA:1.10.10.10 3 70 4.4E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05135 652667333508b63f556240bf916e6a67 244 Gene3D G3DSA:3.40.1410.10 71 236 2.6E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS05135 652667333508b63f556240bf916e6a67 244 SMART SM00345 14 73 4.5E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 SMART SM00866 94 233 3.3E-21 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS05135 652667333508b63f556240bf916e6a67 244 SUPERFAMILY SSF46785 1 81 7.03E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 530 2.3E-145 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Gene3D G3DSA:3.40.50.880 2 220 2.5E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Pfam PF02540 NAD synthase 221 290 1.4E-8 T 06-07-2017 IPR022310 NAD/GMP synthase CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Gene3D G3DSA:3.30.300.10 399 530 8.2E-52 T 06-07-2017 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Pfam PF00117 Glutamine amidotransferase class-I 7 197 1.1E-34 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 SUPERFAMILY SSF54810 403 530 7.06E-47 T 06-07-2017 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 SUPERFAMILY SSF52402 195 417 1.32E-57 T 06-07-2017 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 530 55.006 T 06-07-2017 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Gene3D G3DSA:3.40.50.620 221 397 6.4E-59 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 Pfam PF00958 GMP synthase C terminal domain 443 529 7.4E-42 T 06-07-2017 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 202 2.4E-69 T 06-07-2017 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17035 cce1cf4472fb9de190cbba66c0bb3f02 530 SUPERFAMILY SSF52317 1 235 6.52E-57 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.7E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 205 0.0039 T 06-07-2017 CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 Gene3D G3DSA:3.40.50.720 2 238 8.5E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 Pfam PF00106 short chain dehydrogenase 5 196 5.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17130 bc342001c44d0a618710110ed312495c 251 SUPERFAMILY SSF51735 4 238 1.17E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 Gene3D G3DSA:3.10.310.10 181 360 1.3E-63 T 06-07-2017 CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 SUPERFAMILY SSF54506 1 171 6.2E-66 T 06-07-2017 CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 1 382 5.1E-154 T 06-07-2017 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 SUPERFAMILY SSF54506 177 381 2.04E-63 T 06-07-2017 CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 Pfam PF04303 PrpF protein 3 380 2.0E-144 T 06-07-2017 IPR007400 PrpF protein CAL12_RS20755 439c9531f3c765c0854ceb532445b341 383 Gene3D G3DSA:3.10.310.10 1 180 3.0E-82 T 06-07-2017 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 644 9.7E-194 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:3.90.740.10 210 367 9.4E-44 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 892 956 1.8E-22 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF52374 622 654 7.15E-130 T 06-07-2017 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF52374 370 584 7.15E-130 T 06-07-2017 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF52374 13 208 7.15E-130 T 06-07-2017 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:1.10.287.380 887 952 1.8E-9 T 06-07-2017 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF50677 207 370 1.44E-55 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF46589 892 956 7.85E-17 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:3.40.50.620 622 643 1.1E-134 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:3.40.50.620 15 209 1.1E-134 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:3.40.50.620 370 584 1.1E-134 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 PRINTS PR00986 Valyl-tRNA synthetase signature 52 63 6.4E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 PRINTS PR00986 Valyl-tRNA synthetase signature 375 388 6.4E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 PRINTS PR00986 Valyl-tRNA synthetase signature 488 509 6.4E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 PRINTS PR00986 Valyl-tRNA synthetase signature 519 537 6.4E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 PRINTS PR00986 Valyl-tRNA synthetase signature 259 276 6.4E-35 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Gene3D G3DSA:1.10.730.10 644 831 2.2E-64 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 938 0.0 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Pfam PF08264 Anticodon-binding domain of tRNA 685 838 4.2E-41 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 SUPERFAMILY SSF47323 655 907 1.18E-62 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS09200 b60b3f3cb013be8b5d575f371b821f0b 958 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 957 15.341 T 06-07-2017 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CAL12_RS19495 2fa059982ac6a17e4ea500733130e32c 229 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 8 227 2.0E-30 T 06-07-2017 IPR010843 Uncharacterised protein family AroM CAL12_RS19495 2fa059982ac6a17e4ea500733130e32c 229 Pfam PF07302 AroM protein 8 228 4.5E-75 T 06-07-2017 IPR010843 Uncharacterised protein family AroM CAL12_RS19150 47e5c15f1bedac3fa9808ad33708897d 116 Pfam PF13473 Cupredoxin-like domain 12 112 3.9E-24 T 06-07-2017 IPR028096 EfeO-type cupredoxin-like domain CAL12_RS19150 47e5c15f1bedac3fa9808ad33708897d 116 Gene3D G3DSA:2.60.40.420 16 113 9.6E-9 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS19150 47e5c15f1bedac3fa9808ad33708897d 116 SUPERFAMILY SSF49503 11 113 5.38E-14 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Gene3D G3DSA:3.40.50.2300 441 557 5.5E-34 T 06-07-2017 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 4.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 418 4.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 4.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 399 4.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SUPERFAMILY SSF55874 253 419 6.16E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Gene3D G3DSA:1.10.287.130 193 259 8.2E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SMART SM00388 198 263 1.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SUPERFAMILY SSF47384 192 261 1.96E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SMART SM00448 442 551 3.0E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SUPERFAMILY SSF52172 442 556 1.05E-32 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Pfam PF00072 Response regulator receiver domain 444 551 3.9E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 305 419 1.2E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Gene3D G3DSA:3.30.565.10 263 417 1.4E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 261 7.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26130 e68bda0343df712143a88e29238ddd60 557 SMART SM00387 304 421 1.8E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 2.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 Gene3D G3DSA:3.40.190.10 96 183 9.4E-16 T 06-07-2017 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 SUPERFAMILY SSF46785 5 110 1.18E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 Pfam PF03466 LysR substrate binding domain 93 301 8.1E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 Gene3D G3DSA:1.10.10.10 7 93 5.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 Gene3D G3DSA:3.40.190.10 184 269 4.3E-14 T 06-07-2017 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 5.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 5.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 5.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25185 10f78ad0bb14c4f46da0fe93a47086d4 306 SUPERFAMILY SSF53850 96 304 6.2E-36 T 06-07-2017 CAL12_RS22435 5656f631bc075565c2472337126acd11 576 Gene3D G3DSA:3.90.1310.10 134 234 6.1E-33 T 06-07-2017 CAL12_RS22435 5656f631bc075565c2472337126acd11 576 Gene3D G3DSA:3.40.710.10 235 554 1.4E-80 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS22435 5656f631bc075565c2472337126acd11 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 213 8.7E-21 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAL12_RS22435 5656f631bc075565c2472337126acd11 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 548 3.6E-68 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAL12_RS22435 5656f631bc075565c2472337126acd11 576 SUPERFAMILY SSF56601 179 563 4.44E-86 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS22435 5656f631bc075565c2472337126acd11 576 SUPERFAMILY SSF56519 60 227 2.75E-47 T 06-07-2017 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 SMART SM00382 220 400 3.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 152 2.6E-35 T 06-07-2017 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 Pfam PF01078 Magnesium chelatase, subunit ChlI 201 398 2.1E-88 T 06-07-2017 IPR000523 Magnesium chelatase ChlI domain CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 501 3.1E-154 T 06-07-2017 IPR004482 Mg chelatase-related protein CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 219 234 1.8E-6 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 325 338 1.8E-6 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 349 361 1.8E-6 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 297 311 1.8E-6 T 06-07-2017 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 Gene3D G3DSA:3.30.230.10 5 178 1.8E-22 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 SUPERFAMILY SSF54211 9 180 2.39E-23 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 Gene3D G3DSA:3.40.50.300 201 396 2.8E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 SUPERFAMILY SSF52540 201 503 1.08E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09915 4477cfc41eded045f1a2dda0d2f21be5 504 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 409 501 3.0E-26 T 06-07-2017 IPR025158 Mg chelatase-related protein, C-terminal domain CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 314 2.1E-105 T 06-07-2017 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 313 57.564 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 Gene3D G3DSA:1.10.150.130 8 99 8.7E-23 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 Pfam PF00589 Phage integrase family 112 299 3.0E-36 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 Gene3D G3DSA:1.10.443.10 111 307 7.8E-50 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 SUPERFAMILY SSF56349 9 307 5.3E-51 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAL12_RS26705 516ccda8eafd132533a779878b1a71fe 317 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 84 1.5E-17 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAL12_RS01790 6a907f53d88186753cdd84d23c577e97 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS01790 6a907f53d88186753cdd84d23c577e97 321 Pfam PF00348 Polyprenyl synthetase 32 272 9.3E-75 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS01790 6a907f53d88186753cdd84d23c577e97 321 Gene3D G3DSA:1.10.600.10 6 320 1.6E-98 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS01790 6a907f53d88186753cdd84d23c577e97 321 SUPERFAMILY SSF48576 6 320 5.9E-96 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS01790 6a907f53d88186753cdd84d23c577e97 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 Gene3D G3DSA:3.30.70.580 1 105 6.6E-37 T 06-07-2017 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 4 239 1.2E-67 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 Pfam PF01416 tRNA pseudouridine synthase 10 103 1.8E-8 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 Pfam PF01416 tRNA pseudouridine synthase 143 244 9.2E-30 T 06-07-2017 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 Gene3D G3DSA:3.30.70.660 107 242 1.1E-47 T 06-07-2017 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 PIRSF PIRSF001430 1 257 8.8E-78 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 33.879 T 06-07-2017 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS09690 965e403f9641b464911bc6850c19720a 264 SUPERFAMILY SSF55120 1 249 1.04E-87 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS05700 c414bbf0dec04f827c29c051bdafcbcc 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 6.6E-135 T 06-07-2017 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108 CAL12_RS05700 c414bbf0dec04f827c29c051bdafcbcc 306 Pfam PF01063 Amino-transferase class IV 37 267 5.6E-51 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS05700 c414bbf0dec04f827c29c051bdafcbcc 306 SUPERFAMILY SSF56752 1 303 1.19E-99 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS05700 c414bbf0dec04f827c29c051bdafcbcc 306 Gene3D G3DSA:3.30.470.10 8 130 2.2E-41 T 06-07-2017 CAL12_RS05700 c414bbf0dec04f827c29c051bdafcbcc 306 Gene3D G3DSA:3.20.10.10 135 295 1.4E-53 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 2278 2468 2.78E-35 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 2476 2722 1.33E-36 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00975 Thioesterase domain 5038 5144 1.3E-20 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4564 4575 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.30.300.30 2034 2152 2.2E-35 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.30.300.30 907 1047 1.1E-33 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.30.300.30 3692 3828 9.1E-37 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.30.300.30 4818 4954 2.0E-33 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 3257 3424 2.1E-44 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 511 658 1.1E-37 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 1617 1779 1.4E-44 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3410 3421 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1775 1786 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13745 HxxPF-repeated domain 1472 1564 8.1E-25 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13745 HxxPF-repeated domain 374 465 6.2E-16 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF47336 2142 2211 9.29E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF53474 5024 5286 1.12E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 2972 3225 7.45E-46 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00501 AMP-binding enzyme 1621 2039 5.7E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00501 AMP-binding enzyme 3263 3697 2.0E-95 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00501 AMP-binding enzyme 4414 4823 8.1E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00501 AMP-binding enzyme 514 912 7.9E-85 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF56801 4373 4964 2.35E-143 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF56801 508 1057 1.07E-135 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00668 Condensation domain 3955 4246 7.3E-57 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00668 Condensation domain 47 352 5.0E-66 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00668 Condensation domain 1134 1450 1.3E-65 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00668 Condensation domain 2831 3091 4.0E-49 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00668 Condensation domain 2273 2587 5.3E-57 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF56801 3552 3838 4.97E-152 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF56801 3244 3523 4.97E-152 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1643 2063 4.3E-131 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 534 936 3.2E-112 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3291 3721 6.2E-129 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 4433 4847 4.8E-123 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3849 3864 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.1820 5024 5141 6.4E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.1820 5225 5278 6.4E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 50 233 4.34E-46 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 3953 4144 1.78E-38 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13193 AMP-binding enzyme C-terminal domain 2047 2124 8.6E-11 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13193 AMP-binding enzyme C-terminal domain 3705 3800 3.6E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13193 AMP-binding enzyme C-terminal domain 4831 4927 9.2E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF13193 AMP-binding enzyme C-terminal domain 920 1019 7.4E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SMART SM00824 Thioesterase 5040 5194 0.0098 T 06-07-2017 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 3431 3513 1.3E-43 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 3550 3609 1.3E-43 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00455 Putative AMP-binding domain signature. 653 664 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2173 2188 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF47336 3817 3887 2.62E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4976 4991 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 4130 4374 5.45E-52 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SMART SM00823 Phosphopantetheine attachment site 2149 2217 0.0017 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SMART SM00823 Phosphopantetheine attachment site 3825 3893 0.0016 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SMART SM00823 Phosphopantetheine attachment site 1044 1112 1.0E-5 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 1135 1204 3.89E-42 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 1239 1331 3.89E-42 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 1338 1581 1.02E-54 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:2.30.38.10 825 902 3.1E-26 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:2.30.38.10 4735 4813 3.4E-25 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:2.30.38.10 1950 2029 1.1E-25 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:2.30.38.10 3610 3687 2.5E-26 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2593 2745 4.0E-38 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF47336 4945 5016 8.64E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 239 488 1.45E-46 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF47336 1038 1109 5.37E-19 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF56801 1595 2162 6.41E-154 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00550 Phosphopantetheine attachment site 1046 1108 4.0E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00550 Phosphopantetheine attachment site 3827 3887 2.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00550 Phosphopantetheine attachment site 2151 2211 3.3E-11 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Pfam PF00550 Phosphopantetheine attachment site 4953 5016 9.0E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:1.10.1200.10 4955 5016 1.8E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:1.10.1200.10 2153 2214 1.8E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:1.10.1200.10 3829 3887 8.1E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:1.10.1200.10 1048 1111 3.4E-26 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 659 824 3.9E-31 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 4573 4734 4.6E-35 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 1780 1942 1.5E-46 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 2821 2985 2.89E-38 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 SUPERFAMILY SSF52777 2752 2771 2.89E-38 T 06-07-2017 CAL12_RS11060 8ca5513159ef7718a10bb13e32a439ea 5311 Gene3D G3DSA:3.40.50.980 4408 4572 5.7E-47 T 06-07-2017 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 SMART SM00138 6 269 2.1E-31 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 Gene3D G3DSA:3.40.50.150 72 269 1.1E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 PRINTS PR00996 Glutamate methyltransferase family signature 133 149 2.9E-21 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 2.9E-21 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 2.9E-21 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 PRINTS PR00996 Glutamate methyltransferase family signature 101 121 2.9E-21 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 2.9E-21 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 SUPERFAMILY SSF53335 73 251 7.98E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 254 3.9E-38 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAL12_RS22765 32db047b621ecf45bccd0f127f4e3ca4 271 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 59 1.0E-9 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Pfam PF00378 Enoyl-CoA hydratase/isomerase 537 673 5.1E-12 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Gene3D G3DSA:3.90.226.10 536 674 1.2E-24 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 SUPERFAMILY SSF48179 215 333 9.35E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 32 214 2.4E-45 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 SUPERFAMILY SSF51735 28 215 8.91E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Gene3D G3DSA:3.40.50.720 24 217 6.9E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 217 316 5.3E-12 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 SUPERFAMILY SSF48179 366 458 6.04E-15 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Gene3D G3DSA:1.10.1040.10 369 427 6.8E-8 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 Gene3D G3DSA:1.10.1040.10 218 317 3.8E-16 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS27045 6adc6250afcd59c97da567555b5aecc0 834 SUPERFAMILY SSF52096 533 830 9.3E-37 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 SUPERFAMILY SSF103473 17 423 2.88E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 Pfam PF07690 Major Facilitator Superfamily 25 378 1.1E-24 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 Gene3D G3DSA:1.20.1250.20 17 222 8.3E-26 T 06-07-2017 CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 Gene3D G3DSA:1.20.1250.20 243 421 8.7E-17 T 06-07-2017 CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 296 313 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS23575 d85bbd770d677d56db539120b99775aa 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS20730 d150c7ad4d9e06dc6c55e81fa54814d7 353 PIRSF PIRSF029792 1 337 2.1E-119 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS20730 d150c7ad4d9e06dc6c55e81fa54814d7 353 SUPERFAMILY SSF54506 1 334 2.66E-105 T 06-07-2017 CAL12_RS20730 d150c7ad4d9e06dc6c55e81fa54814d7 353 Pfam PF05544 Proline racemase 10 335 3.9E-122 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS20730 d150c7ad4d9e06dc6c55e81fa54814d7 353 Gene3D G3DSA:3.10.310.10 157 322 6.0E-62 T 06-07-2017 CAL12_RS20730 d150c7ad4d9e06dc6c55e81fa54814d7 353 Gene3D G3DSA:3.10.310.10 1 156 1.3E-56 T 06-07-2017 CAL12_RS06335 c6f41fb3fe486906129b88c9d7ff799a 323 Pfam PF01863 Protein of unknown function DUF45 100 315 7.9E-58 T 06-07-2017 IPR002725 Protein of unknown function DUF45 CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 PRINTS PR00412 Epoxide hydrolase signature 269 291 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 PRINTS PR00412 Epoxide hydrolase signature 34 52 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 PRINTS PR00412 Epoxide hydrolase signature 102 115 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 PRINTS PR00412 Epoxide hydrolase signature 116 129 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 SUPERFAMILY SSF53474 7 294 2.07E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 Gene3D G3DSA:3.40.50.1820 10 294 1.9E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS26635 f8631a2841e70ed59d2963c70cce0509 296 Pfam PF00561 alpha/beta hydrolase fold 28 146 3.0E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS05150 bfd734634dd33749e0b407588227f6f3 399 PIRSF PIRSF007313 1 364 9.8E-154 T 06-07-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CAL12_RS05150 bfd734634dd33749e0b407588227f6f3 399 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 353 2.4E-159 T 06-07-2017 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 CAL12_RS07715 807ca3931c3661b793ea6c4ba802c038 399 SUPERFAMILY SSF103473 14 395 1.26E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS07715 807ca3931c3661b793ea6c4ba802c038 399 Pfam PF07690 Major Facilitator Superfamily 25 314 1.6E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS07715 807ca3931c3661b793ea6c4ba802c038 399 Gene3D G3DSA:1.20.1250.20 217 392 2.7E-15 T 06-07-2017 CAL12_RS07715 807ca3931c3661b793ea6c4ba802c038 399 Gene3D G3DSA:1.20.1250.20 18 194 4.6E-21 T 06-07-2017 CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 Gene3D G3DSA:3.40.190.10 177 261 3.4E-18 T 06-07-2017 CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 Pfam PF03466 LysR substrate binding domain 89 292 1.9E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 SUPERFAMILY SSF46785 4 112 4.22E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 Gene3D G3DSA:3.40.190.10 92 176 9.7E-27 T 06-07-2017 CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 SUPERFAMILY SSF53850 89 295 1.55E-44 T 06-07-2017 CAL12_RS08295 8bebe96040af164dbec77180a5a5c802 302 Gene3D G3DSA:1.10.10.10 4 87 1.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.0E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.0E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.0E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 Pfam PF03466 LysR substrate binding domain 94 292 9.2E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 SUPERFAMILY SSF46785 6 88 1.61E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 Gene3D G3DSA:1.10.10.10 4 88 7.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 Gene3D G3DSA:3.40.190.10 181 261 1.6E-19 T 06-07-2017 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 Gene3D G3DSA:3.40.190.10 95 180 1.4E-15 T 06-07-2017 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 SUPERFAMILY SSF53850 95 294 2.33E-36 T 06-07-2017 CAL12_RS04720 f83a5a1f08613f32cdc4437efde95664 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 3.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 SUPERFAMILY SSF56024 87 312 1.63E-44 T 06-07-2017 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 SUPERFAMILY SSF56024 275 468 1.84E-44 T 06-07-2017 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 Gene3D G3DSA:3.30.870.10 91 315 3.1E-48 T 06-07-2017 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 Pfam PF13091 PLD-like domain 326 449 5.0E-29 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 Pfam PF13091 PLD-like domain 115 223 1.6E-10 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 SMART SM00155 397 424 1.5E-4 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 SMART SM00155 199 226 0.0017 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS17665 b7e3267d7bd9495954ade4953dd6fb5e 484 Gene3D G3DSA:3.30.870.10 316 461 2.9E-39 T 06-07-2017 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 SUPERFAMILY SSF56801 10 614 2.22E-148 T 06-07-2017 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Gene3D G3DSA:3.40.50.980 252 404 2.0E-25 T 06-07-2017 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Gene3D G3DSA:3.40.50.980 57 251 7.5E-34 T 06-07-2017 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 8 58 6.1E-15 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Gene3D G3DSA:3.30.300.30 506 613 3.2E-24 T 06-07-2017 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 ProSitePatterns PS00455 Putative AMP-binding domain signature. 247 258 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Pfam PF00501 AMP-binding enzyme 64 511 7.3E-74 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 5 635 4.8E-299 T 06-07-2017 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Pfam PF13193 AMP-binding enzyme C-terminal domain 520 601 5.9E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS08500 2728935316f7733c274bd3c5926db343 636 Gene3D G3DSA:2.30.38.10 425 505 2.6E-5 T 06-07-2017 CAL12_RS23495 19a5c587bca1a9674df3f4289ae61bfc 234 Pfam PF00881 Nitroreductase family 56 209 3.0E-22 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAL12_RS23495 19a5c587bca1a9674df3f4289ae61bfc 234 SUPERFAMILY SSF55469 52 227 7.59E-31 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS23495 19a5c587bca1a9674df3f4289ae61bfc 234 Gene3D G3DSA:3.40.109.10 51 223 5.1E-38 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 Gene3D G3DSA:3.10.290.10 2 61 1.8E-16 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 SUPERFAMILY SSF55174 3 80 1.44E-12 T 06-07-2017 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 SUPERFAMILY SSF55120 65 241 3.52E-37 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 Pfam PF01479 S4 domain 4 40 1.3E-5 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 107 238 1.1E-36 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAL12_RS15870 41170b6a6fae9e8f383c078b1b7d8c73 243 Pfam PF00849 RNA pseudouridylate synthase 66 207 1.1E-10 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS27170 a4dc4d03fe5f2c039b37178e7595925c 83 SMART SM00530 14 69 7.9E-10 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS27170 a4dc4d03fe5f2c039b37178e7595925c 83 Gene3D G3DSA:1.10.260.40 10 67 1.6E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS27170 a4dc4d03fe5f2c039b37178e7595925c 83 SUPERFAMILY SSF47413 7 70 3.75E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS27170 a4dc4d03fe5f2c039b37178e7595925c 83 Pfam PF01381 Helix-turn-helix 18 65 1.0E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 136 4.1E-12 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 137 148 4.1E-12 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 165 177 4.1E-12 T 06-07-2017 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 TIGRFAM TIGR00498 lexA: repressor LexA 3 212 1.5E-71 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 SUPERFAMILY SSF46785 4 71 4.42E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 SUPERFAMILY SSF51306 90 211 1.06E-33 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 Pfam PF00717 Peptidase S24-like 129 194 6.4E-16 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 Pfam PF01726 LexA DNA binding domain 3 66 1.2E-28 T 06-07-2017 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 Gene3D G3DSA:1.10.10.10 3 69 1.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 Gene3D G3DSA:2.10.109.10 91 212 1.0E-40 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAL12_RS17200 fa5301d8783ac15adb1f7d4e6f452ee5 216 Hamap MF_00015 LexA repressor [lexA]. 4 213 32.42 T 06-07-2017 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 Gene3D G3DSA:1.20.5.1030 64 121 1.2E-23 T 06-07-2017 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 6.7E-20 T 06-07-2017 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 118 6.3E-18 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 121 11.631 T 06-07-2017 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 6.1E-8 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 6.1E-8 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAL12_RS27780 e03f6c17a7bfba18abe92822e323846f 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 6.1E-8 T 06-07-2017 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 328 57.386 T 06-07-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 Gene3D G3DSA:3.40.50.720 2 169 9.0E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 Gene3D G3DSA:3.90.25.10 170 309 3.6E-31 T 06-07-2017 CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 SUPERFAMILY SSF51735 2 328 5.18E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 240 1.3E-41 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS18895 9d562b601f0e18cd5fd75db3c53402e4 329 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 325 2.2E-127 T 06-07-2017 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 CAL12_RS18790 b358526e34a18131fedd9f11879e1603 301 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 14 280 3.5E-91 T 06-07-2017 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CAL12_RS18790 b358526e34a18131fedd9f11879e1603 301 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 20 277 1.6E-67 T 06-07-2017 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CAL12_RS18790 b358526e34a18131fedd9f11879e1603 301 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 301 131.604 T 06-07-2017 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Pfam PF01330 RuvA N terminal domain 1 62 9.8E-22 T 06-07-2017 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 SUPERFAMILY SSF46929 146 189 6.93E-8 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Gene3D G3DSA:1.10.150.20 68 134 2.4E-27 T 06-07-2017 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 189 30.259 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Gene3D G3DSA:2.40.50.140 1 65 4.9E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 SUPERFAMILY SSF47781 65 132 2.11E-19 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Gene3D G3DSA:1.10.8.10 145 188 3.4E-7 T 06-07-2017 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 188 7.9E-51 T 06-07-2017 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 SUPERFAMILY SSF50249 1 63 8.0E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 SMART SM00278 73 92 3.5 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 SMART SM00278 108 127 0.0015 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Pfam PF07499 RuvA, C-terminal domain 147 188 8.2E-12 T 06-07-2017 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CAL12_RS05580 5ee7461f286fd26abed0b3658b3d3ee6 190 Pfam PF14520 Helix-hairpin-helix domain 72 129 1.9E-17 T 06-07-2017 CAL12_RS27820 ae303534e71c02ce08fe7ee9cb294365 461 Gene3D G3DSA:3.30.590.10 123 449 7.7E-95 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAL12_RS27820 ae303534e71c02ce08fe7ee9cb294365 461 SUPERFAMILY SSF55931 120 459 2.55E-102 T 06-07-2017 CAL12_RS27820 ae303534e71c02ce08fe7ee9cb294365 461 SMART SM01230 120 376 2.5E-91 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS27820 ae303534e71c02ce08fe7ee9cb294365 461 Pfam PF00120 Glutamine synthetase, catalytic domain 121 457 1.3E-94 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 SUPERFAMILY SSF52540 8 243 7.38E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 Pfam PF08402 TOBE domain 282 349 1.9E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 Pfam PF00005 ABC transporter 24 165 2.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 SUPERFAMILY SSF50331 243 350 2.66E-8 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 Gene3D G3DSA:3.40.50.300 6 237 8.3E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 SMART SM00382 32 215 7.6E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10480 2591d0760a0a4f64686bce419c78e261 356 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 Gene3D G3DSA:2.40.50.140 3 66 7.9E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 PIRSF PIRSF002599 1 68 1.1E-25 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 2.4E-30 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 PRINTS PR00050 Cold shock protein signature 5 20 7.2E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 PRINTS PR00050 Cold shock protein signature 26 35 7.2E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 PRINTS PR00050 Cold shock protein signature 41 59 7.2E-18 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 SUPERFAMILY SSF50249 2 67 1.91E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27860 e35ccbbf02e4a17b84a9207ab78a3265 68 SMART SM00357 4 68 1.2E-30 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 Pfam PF00281 Ribosomal protein L5 25 80 5.9E-26 T 06-07-2017 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 SUPERFAMILY SSF55282 3 179 3.06E-75 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 Gene3D G3DSA:3.30.1440.10 1 179 8.2E-74 T 06-07-2017 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.9E-40 T 06-07-2017 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.378 T 06-07-2017 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 PIRSF PIRSF002161 1 179 1.3E-60 T 06-07-2017 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27565 c8493566601d905dbfe7742e9132c42a 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 06-07-2017 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 Gene3D G3DSA:3.50.50.60 30 131 1.1E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 Gene3D G3DSA:3.50.50.60 185 265 1.1E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 Gene3D G3DSA:3.50.50.60 359 409 1.1E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 SUPERFAMILY SSF51905 17 262 3.11E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 SUPERFAMILY SSF51905 314 398 3.11E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 37 59 2.2E-5 T 06-07-2017 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 322 2.2E-5 T 06-07-2017 CAL12_RS15115 f4b54ffa63417638a26641ba466b418d 444 Pfam PF01266 FAD dependent oxidoreductase 37 390 2.4E-50 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 Pfam PF00107 Zinc-binding dehydrogenase 151 267 8.8E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 323 5.8E-117 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 3.2E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 Gene3D G3DSA:3.90.180.10 1 145 1.6E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 SUPERFAMILY SSF50129 1 140 8.98E-31 T 06-07-2017 IPR011032 GroES-like CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 SUPERFAMILY SSF51735 111 287 2.8E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 SMART SM00829 10 323 3.2E-46 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS14430 546ec82bf2e767c543a2ab169cbaded0 325 Gene3D G3DSA:3.40.50.720 146 260 4.3E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 322 1.1E-142 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 SUPERFAMILY SSF51735 5 158 1.63E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 PIRSF PIRSF000102 2 328 3.3E-64 T 06-07-2017 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 Gene3D G3DSA:3.40.50.720 5 156 5.3E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 153 4.4E-37 T 06-07-2017 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.461 T 06-07-2017 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 SUPERFAMILY SSF56327 160 328 1.42E-59 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 Gene3D G3DSA:3.90.110.10 158 328 3.2E-71 T 06-07-2017 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CAL12_RS19290 605921680928d12608e2f9820c4b47fe 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 324 1.6E-30 T 06-07-2017 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 250 2.4E-84 T 06-07-2017 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 SUPERFAMILY SSF52540 3 243 1.21E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 Pfam PF00005 ABC transporter 21 181 2.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 Gene3D G3DSA:3.40.50.300 4 243 2.7E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05075 ee38356ee38d90184435c501b78ac171 285 SMART SM00382 30 238 6.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.3E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 253 1.7E-43 T 06-07-2017 CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 Gene3D G3DSA:3.40.50.720 4 254 2.0E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 SUPERFAMILY SSF51735 6 254 1.51E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18010 7501d111b753ff0ac88d92c2114c4fc0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 5.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 SUPERFAMILY SSF53474 21 260 2.57E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00412 Epoxide hydrolase signature 49 64 2.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00412 Epoxide hydrolase signature 29 47 2.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00412 Epoxide hydrolase signature 236 258 2.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 Gene3D G3DSA:3.40.50.1820 24 260 4.3E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 Pfam PF12697 Alpha/beta hydrolase family 25 253 1.4E-23 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 2.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 2.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 2.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS03965 90cf8aeabee6995d3944b6ce89f9542b 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 2.3E-8 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS04475 86e46a222ed9e3f0e940f9fa8efc7ad3 357 PIRSF PIRSF017082 28 357 2.8E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04475 86e46a222ed9e3f0e940f9fa8efc7ad3 357 SUPERFAMILY SSF53850 142 313 3.37E-15 T 06-07-2017 CAL12_RS04475 86e46a222ed9e3f0e940f9fa8efc7ad3 357 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 81 353 1.3E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 SUPERFAMILY SSF53850 27 508 5.79E-129 T 06-07-2017 CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 Gene3D G3DSA:3.90.76.10 43 189 1.4E-40 T 06-07-2017 CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 Gene3D G3DSA:3.40.190.10 190 290 1.7E-38 T 06-07-2017 CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 Gene3D G3DSA:3.10.105.10 291 478 1.4E-39 T 06-07-2017 CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 73 429 5.0E-91 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS24665 79f95e16b2cbcf3b1d4fe13d42874f2a 509 PIRSF PIRSF002741 1 507 8.7E-98 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS23325 6d88c17031c62b793683eac81832ca33 521 Pfam PF01425 Amidase 32 456 2.5E-91 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23325 6d88c17031c62b793683eac81832ca33 521 SUPERFAMILY SSF75304 4 463 2.62E-123 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23325 6d88c17031c62b793683eac81832ca33 521 Gene3D G3DSA:3.90.1300.10 8 470 4.0E-118 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 SUPERFAMILY SSF55124 1 125 1.96E-29 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Gene3D G3DSA:3.30.413.10 408 563 6.6E-34 T 06-07-2017 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 SUPERFAMILY SSF56014 408 562 4.84E-35 T 06-07-2017 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 SUPERFAMILY SSF56014 120 285 1.57E-46 T 06-07-2017 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 8.6E-15 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 329 397 3.1E-15 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 453 562 4.7E-8 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 270 1.2E-39 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Gene3D G3DSA:3.30.413.10 120 276 5.1E-40 T 06-07-2017 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Gene3D G3DSA:3.90.480.10 321 403 1.8E-35 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 Gene3D G3DSA:3.90.480.10 48 117 1.8E-35 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 SUPERFAMILY SSF55124 251 275 1.64E-25 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS07010 aed08ed77d5897d20f6e5e81f2a88aa7 577 SUPERFAMILY SSF55124 315 421 1.64E-25 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 Gene3D G3DSA:2.30.40.10 383 415 4.0E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 Gene3D G3DSA:2.30.40.10 7 65 4.0E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 SUPERFAMILY SSF51338 373 413 2.31E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 SUPERFAMILY SSF51338 7 64 2.31E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 SUPERFAMILY SSF51556 64 371 1.66E-65 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 Gene3D G3DSA:2.30.40.10 359 382 6.1E-7 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 Pfam PF01979 Amidohydrolase family 60 413 1.0E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23525 3a743b234055e9f75f067798b995de0b 442 Gene3D G3DSA:3.20.20.140 66 358 3.9E-64 T 06-07-2017 CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 Pfam PF03772 Competence protein 231 529 3.9E-50 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 Pfam PF00753 Metallo-beta-lactamase superfamily 566 771 1.2E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 Gene3D G3DSA:3.60.15.10 555 817 4.1E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 SUPERFAMILY SSF56281 555 819 3.52E-40 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 Pfam PF13567 Domain of unknown function (DUF4131) 14 188 2.4E-16 T 06-07-2017 IPR025405 Domain of unknown function DUF4131 CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 SMART SM00849 567 780 4.4E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 252 455 2.4E-13 T 06-07-2017 IPR004477 ComEC/Rec2-related protein CAL12_RS17085 32a3180ce0dfd1708d9e3711b50ee727 839 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 147 811 5.3E-78 T 06-07-2017 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CAL12_RS27410 c7ce96b008294b2b2ecd3e05cc7f6f06 221 SUPERFAMILY SSF47616 80 203 4.12E-18 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS27410 c7ce96b008294b2b2ecd3e05cc7f6f06 221 Gene3D G3DSA:1.20.1050.10 96 207 8.9E-42 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS27410 c7ce96b008294b2b2ecd3e05cc7f6f06 221 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 80 8.4E-13 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS27410 c7ce96b008294b2b2ecd3e05cc7f6f06 221 Gene3D G3DSA:3.40.30.10 10 95 2.8E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS27410 c7ce96b008294b2b2ecd3e05cc7f6f06 221 SUPERFAMILY SSF52833 3 86 1.63E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 Gene3D G3DSA:3.40.50.1950 4 186 4.0E-66 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 Pfam PF02441 Flavoprotein 7 135 4.2E-34 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 SUPERFAMILY SSF52507 3 182 8.9E-61 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 Gene3D G3DSA:3.40.50.10300 187 396 1.1E-78 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 392 1.2E-127 T 06-07-2017 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 SUPERFAMILY SSF102645 184 396 1.31E-70 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAL12_RS17305 3620b80d1e58446da33a731548854a99 398 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 367 4.2E-64 T 06-07-2017 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CAL12_RS14620 596f218a0f74d98d61a675dab0b27a9c 326 Gene3D G3DSA:3.40.190.10 131 227 4.4E-4 T 06-07-2017 CAL12_RS14620 596f218a0f74d98d61a675dab0b27a9c 326 SUPERFAMILY SSF53850 120 281 3.26E-13 T 06-07-2017 CAL12_RS14620 596f218a0f74d98d61a675dab0b27a9c 326 PIRSF PIRSF017082 2 324 1.0E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14620 596f218a0f74d98d61a675dab0b27a9c 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 2.6E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27485 66820126ebdd228379ceca08121c9eb7 115 Gene3D G3DSA:3.30.70.830 4 109 2.3E-34 T 06-07-2017 CAL12_RS27485 66820126ebdd228379ceca08121c9eb7 115 Pfam PF03091 CutA1 divalent ion tolerance protein 8 104 1.8E-29 T 06-07-2017 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CAL12_RS27485 66820126ebdd228379ceca08121c9eb7 115 SUPERFAMILY SSF54913 4 106 3.45E-33 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 376 7.3E-97 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 Gene3D G3DSA:3.40.640.10 8 246 5.4E-74 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 Gene3D G3DSA:3.90.1150.10 247 376 5.6E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 11 375 7.0E-117 T 06-07-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 SUPERFAMILY SSF53383 16 376 1.12E-88 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS26295 9a0f53143b5508057710b7ddf8354b08 392 PIRSF PIRSF001434 2 378 8.8E-111 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 467 1.9E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Gene3D G3DSA:1.10.287.130 242 306 7.4E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Gene3D G3DSA:3.30.565.10 321 469 1.6E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Pfam PF08521 Two-component sensor kinase N-terminal 37 173 1.3E-35 T 06-07-2017 IPR013727 Two-component sensor kinase, N-terminal CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 SUPERFAMILY SSF53850 540 804 7.25E-42 T 06-07-2017 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 SMART SM00387 359 469 2.6E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Gene3D G3DSA:3.40.190.10 776 850 1.3E-44 T 06-07-2017 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Gene3D G3DSA:3.40.190.10 528 634 1.3E-44 T 06-07-2017 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 SMART SM00388 249 314 4.0E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 410 5.5E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 447 5.5E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 PRINTS PR00344 Bacterial sensor protein C-terminal signature 453 466 5.5E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Pfam PF00512 His Kinase A (phospho-acceptor) domain 249 312 7.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 SUPERFAMILY SSF47384 232 309 3.34E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 SUPERFAMILY SSF55874 321 473 6.68E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Gene3D G3DSA:3.40.190.10 635 775 9.2E-50 T 06-07-2017 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Pfam PF13531 Bacterial extracellular solute-binding protein 541 794 3.2E-14 T 06-07-2017 CAL12_RS24905 c58524008ae64a43eadd8cbda67398e7 865 Pfam PF00672 HAMP domain 181 244 2.6E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 Gene3D G3DSA:3.20.20.120 120 365 1.6E-87 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 SUPERFAMILY SSF51604 98 386 2.88E-78 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 13 110 5.4E-32 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 Gene3D G3DSA:3.30.390.10 1 119 1.8E-50 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 Pfam PF13378 Enolase C-terminal domain-like 140 377 1.5E-42 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 SMART SM00922 128 257 2.0E-19 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 207 238 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS19095 8f0c0458520b20b62225b5e2891dd8de 402 SUPERFAMILY SSF54826 1 112 5.16E-33 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS22790 3dfcd4c0113a9fd4626658dafd10960b 340 Gene3D G3DSA:2.130.10.10 37 332 1.1E-47 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS22790 3dfcd4c0113a9fd4626658dafd10960b 340 Pfam PF10282 Lactonase, 7-bladed beta-propeller 238 316 7.3E-5 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAL12_RS22790 3dfcd4c0113a9fd4626658dafd10960b 340 Pfam PF10282 Lactonase, 7-bladed beta-propeller 56 193 5.6E-6 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAL12_RS22790 3dfcd4c0113a9fd4626658dafd10960b 340 SUPERFAMILY SSF50974 9 333 4.45E-68 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CAL12_RS24435 85ee0f4f2c2abd21b335d7ec13f8517f 320 SUPERFAMILY SSF53850 96 283 3.91E-9 T 06-07-2017 CAL12_RS24435 85ee0f4f2c2abd21b335d7ec13f8517f 320 PIRSF PIRSF017082 1 320 5.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24435 85ee0f4f2c2abd21b335d7ec13f8517f 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 315 3.5E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 SUPERFAMILY SSF56235 5 357 3.28E-130 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 SUPERFAMILY SSF56235 415 610 3.28E-130 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 Pfam PF01019 Gamma-glutamyltranspeptidase 31 603 1.2E-114 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 1.1E-20 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 38 63 1.1E-20 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 1.1E-20 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 109 127 1.1E-20 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS20735 ee7ba131807ed1fea8c330fc14d4bc84 611 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 127 146 1.1E-20 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS03070 bacd8c5e229ea99748d2872f246e3abd 314 Gene3D G3DSA:1.10.3720.10 89 303 6.9E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03070 bacd8c5e229ea99748d2872f246e3abd 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 2.5E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03070 bacd8c5e229ea99748d2872f246e3abd 314 SUPERFAMILY SSF161098 90 297 4.36E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19745 a35a1c92b9869053bbc33eabf84ac1e0 117 SUPERFAMILY SSF46785 6 111 1.31E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19745 a35a1c92b9869053bbc33eabf84ac1e0 117 Pfam PF01638 HxlR-like helix-turn-helix 20 104 4.4E-18 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS19745 a35a1c92b9869053bbc33eabf84ac1e0 117 Gene3D G3DSA:1.10.10.10 1 109 7.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Pfam PF13180 PDZ domain 101 177 7.1E-11 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Gene3D G3DSA:3.30.750.44 56 106 1.3E-7 T 06-07-2017 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 SUPERFAMILY SSF50156 91 184 4.54E-20 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 SUPERFAMILY SSF52096 37 119 4.8E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 SUPERFAMILY SSF52096 193 387 4.8E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Gene3D G3DSA:2.30.42.10 107 183 7.5E-28 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 SMART SM00228 101 172 1.2E-17 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Pfam PF03572 Peptidase family S41 199 378 4.1E-52 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Gene3D G3DSA:3.90.226.10 184 381 1.6E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 Gene3D G3DSA:3.90.226.10 423 448 1.6E-65 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 53 381 9.9E-93 T 06-07-2017 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 CAL12_RS26180 7d054cd8dbd4c246eff08f19f182d7dc 489 SMART SM00245 174 379 2.0E-56 T 06-07-2017 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 SMART SM00344 3 112 4.0E-43 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.6E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.6E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.6E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 SUPERFAMILY SSF54909 66 147 6.57E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 Gene3D G3DSA:3.30.70.920 56 148 1.1E-29 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 1.8E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 5.2E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 SUPERFAMILY SSF46785 2 63 2.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00440 7e7ae4fbca4313c68bccbfe3703fabbe 159 Gene3D G3DSA:1.10.10.10 1 54 1.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 324 336 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SMART SM01086 814 904 1.8E-9 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Gene3D G3DSA:3.40.50.300 190 372 5.2E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Gene3D G3DSA:3.40.50.300 603 824 8.7E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 815 884 1.1E-10 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 14 898 0.0 T 06-07-2017 IPR017729 Type VI secretion system, ATPase ClpV1 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 233 345 6.8E-9 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Pfam PF07724 AAA domain (Cdc48 subfamily) 641 808 2.8E-36 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SMART SM00382 228 373 3.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SMART SM00382 642 802 3.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SUPERFAMILY SSF81923 12 129 1.19E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Gene3D G3DSA:1.10.1780.10 10 131 2.1E-15 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Gene3D G3DSA:1.10.8.60 825 905 1.1E-10 T 06-07-2017 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SUPERFAMILY SSF52540 591 881 1.51E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 SUPERFAMILY SSF52540 189 511 9.98E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 Gene3D G3DSA:1.10.8.60 374 457 3.9E-26 T 06-07-2017 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 720 738 1.5E-30 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 691 709 1.5E-30 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.5E-30 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS22695 51b669e44740a62e031c5631a1f23f74 919 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 753 767 1.5E-30 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS17455 b80bbf3d80970324aaec0731d259a401 254 SUPERFAMILY SSF53448 3 249 6.31E-61 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS17455 b80bbf3d80970324aaec0731d259a401 254 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 251 40.717 T 06-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CAL12_RS17455 b80bbf3d80970324aaec0731d259a401 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 244 2.6E-79 T 06-07-2017 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 CAL12_RS17455 b80bbf3d80970324aaec0731d259a401 254 Pfam PF02348 Cytidylyltransferase 4 222 3.2E-52 T 06-07-2017 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 CAL12_RS17455 b80bbf3d80970324aaec0731d259a401 254 Gene3D G3DSA:3.90.550.10 3 252 1.7E-77 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 SUPERFAMILY SSF81606 462 664 7.32E-9 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 Pfam PF08269 Cache domain 40 320 4.0E-23 T 06-07-2017 IPR004010 Double Cache domain 2 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 SMART SM00331 449 665 3.3E-55 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 Gene3D G3DSA:3.60.40.10 530 664 7.2E-4 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 Gene3D G3DSA:3.30.450.20 69 211 6.4E-23 T 06-07-2017 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 Pfam PF00672 HAMP domain 334 409 5.6E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 SMART SM01049 67 160 7.1E-10 T 06-07-2017 IPR033480 Single Cache domain 2 CAL12_RS14990 a7a048ac618d73b940798e988f59b2bb 666 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 475 665 9.8E-53 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 SUPERFAMILY SSF48498 99 224 4.08E-31 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 Gene3D G3DSA:1.10.10.60 63 86 2.3E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 Gene3D G3DSA:1.10.10.60 21 62 1.7E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 6.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 6.8E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 Gene3D G3DSA:1.10.357.10 87 224 9.8E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 Pfam PF08362 YcdC-like protein, C-terminal region 99 225 9.5E-6 T 06-07-2017 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 3.3E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS15680 4bdfc43cb6eb3882c2369b628f81a438 241 SUPERFAMILY SSF46689 19 101 2.72E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01260 d31bda09c9720ba1bcbcdef73d9cd51d 287 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 247 8.4E-50 T 06-07-2017 CAL12_RS01260 d31bda09c9720ba1bcbcdef73d9cd51d 287 ProSitePatterns PS00161 Isocitrate lyase signature. 116 121 - T 06-07-2017 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CAL12_RS01260 d31bda09c9720ba1bcbcdef73d9cd51d 287 Gene3D G3DSA:3.20.20.60 4 285 1.6E-86 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS01260 d31bda09c9720ba1bcbcdef73d9cd51d 287 SUPERFAMILY SSF51621 4 286 1.48E-89 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 SMART SM00421 136 193 2.4E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 Gene3D G3DSA:3.40.50.2300 2 110 4.3E-27 T 06-07-2017 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 SMART SM00448 1 105 4.3E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 SUPERFAMILY SSF46894 132 199 8.16E-17 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 4.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 4.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 4.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 Gene3D G3DSA:1.10.10.10 111 199 7.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 Pfam PF00072 Response regulator receiver domain 2 105 2.3E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 SUPERFAMILY SSF52172 2 120 2.99E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS21325 da1eadfe91d86882bf94d04bfc461f30 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 193 2.8E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS17450 34d6fe53a0189936b3ddafaf1441af4e 62 Gene3D G3DSA:2.20.25.10 8 57 2.6E-26 T 06-07-2017 CAL12_RS17450 34d6fe53a0189936b3ddafaf1441af4e 62 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.934 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAL12_RS17450 34d6fe53a0189936b3ddafaf1441af4e 62 SUPERFAMILY SSF158997 1 54 3.79E-21 T 06-07-2017 CAL12_RS17450 34d6fe53a0189936b3ddafaf1441af4e 62 Pfam PF03966 Trm112p-like protein 4 41 8.9E-12 T 06-07-2017 IPR005651 Uncharacterised protein family UPF0434/Trm112 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 153 1.0E-21 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 Gene3D G3DSA:1.10.10.10 103 158 2.1E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 Pfam PF08281 Sigma-70, region 4 106 156 1.3E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 Gene3D G3DSA:1.10.1740.10 4 99 2.4E-12 T 06-07-2017 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 SUPERFAMILY SSF88946 4 92 4.32E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 Pfam PF04542 Sigma-70 region 2 9 75 3.4E-14 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS14220 40dc893d29a50b8f6529031b83d6bc60 163 SUPERFAMILY SSF88659 101 162 4.91E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 Pfam PF02699 Preprotein translocase subunit 22 102 1.4E-31 T 06-07-2017 IPR003849 Preprotein translocase YajC CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 SMART SM01323 19 105 5.7E-45 T 06-07-2017 IPR003849 Preprotein translocase YajC CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 Gene3D G3DSA:2.60.40.10 58 105 5.0E-4 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 3.8E-17 T 06-07-2017 IPR003849 Preprotein translocase YajC CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 3.8E-17 T 06-07-2017 IPR003849 Preprotein translocase YajC CAL12_RS04925 b4fa45c8f995f46e756a158ecc8f261d 113 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 105 6.9E-26 T 06-07-2017 IPR003849 Preprotein translocase YajC CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 Gene3D G3DSA:3.40.190.10 115 207 4.0E-21 T 06-07-2017 CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 Pfam PF03466 LysR substrate binding domain 116 320 3.7E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 Gene3D G3DSA:3.40.190.10 208 290 1.2E-5 T 06-07-2017 CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 Gene3D G3DSA:1.10.10.10 28 111 3.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 89 1.4E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 SUPERFAMILY SSF46785 18 138 2.29E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07420 40109b3aded85581c58d325ebc2572cf 332 SUPERFAMILY SSF53850 116 322 2.71E-33 T 06-07-2017 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 6.5E-16 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 Gene3D G3DSA:1.10.357.10 59 185 8.3E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 SUPERFAMILY SSF46689 2 75 4.36E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 Gene3D G3DSA:1.10.10.60 2 58 4.1E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 6.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 6.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20445 e0122d577d84e106c7004c292a387a07 199 SUPERFAMILY SSF48498 83 185 1.33E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 SUPERFAMILY SSF51735 163 351 3.1E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 Pfam PF00107 Zinc-binding dehydrogenase 196 276 7.8E-12 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 SUPERFAMILY SSF50129 1 202 3.04E-59 T 06-07-2017 IPR011032 GroES-like CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 Gene3D G3DSA:3.90.180.10 1 187 1.1E-55 T 06-07-2017 IPR011032 GroES-like CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 149 6.6E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 7.4E-10 T 06-07-2017 IPR027399 Alcohol dehydrogenase GroES-associated CAL12_RS04265 50986125295478bb77c7d91d558d9430 389 Gene3D G3DSA:3.40.50.720 188 331 4.9E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 Gene3D G3DSA:3.40.190.10 88 181 4.9E-16 T 06-07-2017 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 SUPERFAMILY SSF46785 1 87 2.12E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 Gene3D G3DSA:3.40.190.10 182 261 1.7E-11 T 06-07-2017 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 SUPERFAMILY SSF53850 88 297 1.39E-35 T 06-07-2017 CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 Gene3D G3DSA:1.10.10.10 1 87 2.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18830 98ddab33f91144252bd4d5285c613447 302 Pfam PF03466 LysR substrate binding domain 87 293 1.2E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02050 4b0e8a3a95d519f2abb787b9b63a8832 280 Gene3D G3DSA:3.60.130.10 2 280 2.3E-89 T 06-07-2017 CAL12_RS02050 4b0e8a3a95d519f2abb787b9b63a8832 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 4 273 6.1E-66 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS02050 4b0e8a3a95d519f2abb787b9b63a8832 280 SUPERFAMILY SSF51197 2 280 3.98E-84 T 06-07-2017 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 SUPERFAMILY SSF53901 4 271 2.23E-77 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Pfam PF00108 Thiolase, N-terminal domain 5 261 2.7E-86 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 PIRSF PIRSF000429 1 394 5.1E-121 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Gene3D G3DSA:3.40.47.10 195 276 1.2E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Gene3D G3DSA:3.40.47.10 4 125 1.2E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 3.0E-133 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Pfam PF02803 Thiolase, C-terminal domain 272 393 1.1E-41 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Gene3D G3DSA:3.40.47.10 278 393 3.6E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 Gene3D G3DSA:3.40.47.10 145 194 3.6E-62 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 SUPERFAMILY SSF53901 273 393 1.2E-41 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS04410 105c644e6104c0185579d20c738aa5fd 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 Gene3D G3DSA:3.40.190.10 110 213 1.9E-31 T 06-07-2017 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 SMART SM00062 33 252 4.0E-72 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 55 68 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 251 4.0E-70 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 Gene3D G3DSA:3.40.190.10 31 109 2.7E-44 T 06-07-2017 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 Gene3D G3DSA:3.40.190.10 214 252 2.7E-44 T 06-07-2017 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 SMART SM00079 33 251 4.2E-11 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAL12_RS15475 e33423a8236e4191c5a569fb3b2b579f 254 SUPERFAMILY SSF53850 5 252 2.18E-76 T 06-07-2017 CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 73 95 - T 06-07-2017 IPR023765 Solute-binding protein family 5, conserved site CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 437 1.9E-83 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 Gene3D G3DSA:3.10.105.10 299 485 1.6E-39 T 06-07-2017 CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 Gene3D G3DSA:3.40.190.10 189 298 7.4E-27 T 06-07-2017 CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 SUPERFAMILY SSF53850 27 503 1.03E-110 T 06-07-2017 CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 PIRSF PIRSF002741 12 508 1.3E-85 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS03050 2101f2ae01d9670cc1770f632595cbb7 516 Gene3D G3DSA:3.90.76.10 35 188 4.2E-39 T 06-07-2017 CAL12_RS16325 7c0b944a0754126b68e8aaf9cfd1c9e0 370 Gene3D G3DSA:3.40.50.1820 45 169 1.2E-11 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16325 7c0b944a0754126b68e8aaf9cfd1c9e0 370 Pfam PF10503 Esterase PHB depolymerase 268 339 3.5E-7 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAL12_RS16325 7c0b944a0754126b68e8aaf9cfd1c9e0 370 Pfam PF10503 Esterase PHB depolymerase 25 168 1.3E-9 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAL12_RS16325 7c0b944a0754126b68e8aaf9cfd1c9e0 370 SUPERFAMILY SSF53474 44 363 5.04E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03365 58860d64c7a98c50f3aeb97d7ad0065a 387 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 54 308 1.2E-28 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS03365 58860d64c7a98c50f3aeb97d7ad0065a 387 Gene3D G3DSA:3.60.130.10 30 311 9.2E-36 T 06-07-2017 CAL12_RS03365 58860d64c7a98c50f3aeb97d7ad0065a 387 SUPERFAMILY SSF51197 26 326 6.41E-47 T 06-07-2017 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 416 47.095 T 06-07-2017 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Gene3D G3DSA:3.30.9.10 135 193 1.3E-11 T 06-07-2017 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Gene3D G3DSA:3.30.9.10 274 358 1.3E-11 T 06-07-2017 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 SUPERFAMILY SSF51905 1 54 3.5E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 SUPERFAMILY SSF51905 107 275 3.5E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 SUPERFAMILY SSF51905 365 413 3.5E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Pfam PF01266 FAD dependent oxidoreductase 3 403 6.3E-63 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Gene3D G3DSA:3.40.50.720 359 411 2.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Gene3D G3DSA:3.40.50.720 194 273 2.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 Gene3D G3DSA:3.40.50.720 1 96 2.2E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09125 990d65d900b32fdfb3993571f57c050b 418 SUPERFAMILY SSF54373 275 365 1.44E-15 T 06-07-2017 CAL12_RS23620 06645a8c433e1bf04040750287c3898b 206 Pfam PF12951 Passenger-associated-transport-repeat 179 206 5.9E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23620 06645a8c433e1bf04040750287c3898b 206 SUPERFAMILY SSF51126 9 206 2.67E-9 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23620 06645a8c433e1bf04040750287c3898b 206 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 176 206 1.9E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS16505 ee23fad3bd193e999f08a734a20e38d0 128 SUPERFAMILY SSF54427 4 128 4.2E-33 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS16505 ee23fad3bd193e999f08a734a20e38d0 128 Pfam PF07366 SnoaL-like polyketide cyclase 10 128 5.1E-36 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS16505 ee23fad3bd193e999f08a734a20e38d0 128 Gene3D G3DSA:3.10.450.50 8 128 1.2E-20 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS23985 0dc4fb2c5d68dfc3fc758bfcd15cea90 117 Pfam PF04273 Putative phosphatase (DUF442) 6 113 6.4E-35 T 06-07-2017 IPR005939 Beta-lactamase hydrolase-like GO:0016787 CAL12_RS23985 0dc4fb2c5d68dfc3fc758bfcd15cea90 117 SUPERFAMILY SSF52799 5 108 6.0E-5 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAL12_RS23985 0dc4fb2c5d68dfc3fc758bfcd15cea90 117 Gene3D G3DSA:3.90.190.10 5 113 3.6E-37 T 06-07-2017 IPR029021 Protein-tyrosine phosphatase-like CAL12_RS23985 0dc4fb2c5d68dfc3fc758bfcd15cea90 117 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 112 1.7E-33 T 06-07-2017 IPR005939 Beta-lactamase hydrolase-like GO:0016787 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 74 734 3.3E-88 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 Gene3D G3DSA:2.40.170.20 184 734 2.9E-132 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 Gene3D G3DSA:2.170.130.10 37 179 7.5E-34 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 170 8.0E-20 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 Pfam PF00593 TonB dependent receptor 505 733 3.4E-32 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS04450 d8737922bff701d45ed492f0e902abae 736 SUPERFAMILY SSF56935 37 734 2.84E-124 T 06-07-2017 CAL12_RS12065 e2adee7616c1f8690084e27c84915312 469 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 16 112 2.2E-18 T 06-07-2017 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CAL12_RS12065 e2adee7616c1f8690084e27c84915312 469 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 227 453 8.2E-39 T 06-07-2017 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CAL12_RS25175 6aea5d782bbe9ec1c6c234d0b1becc6e 397 Gene3D G3DSA:3.40.50.10540 306 396 1.5E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25175 6aea5d782bbe9ec1c6c234d0b1becc6e 397 Gene3D G3DSA:3.40.50.10540 3 217 1.5E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25175 6aea5d782bbe9ec1c6c234d0b1becc6e 397 SUPERFAMILY SSF89796 4 396 3.92E-130 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25175 6aea5d782bbe9ec1c6c234d0b1becc6e 397 Pfam PF02515 CoA-transferase family III 6 373 5.9E-124 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS25175 6aea5d782bbe9ec1c6c234d0b1becc6e 397 Gene3D G3DSA:3.30.1540.10 224 305 9.5E-26 T 06-07-2017 CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 SUPERFAMILY SSF53955 69 290 8.15E-60 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 SUPERFAMILY SSF56601 241 263 7.51E-97 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 SUPERFAMILY SSF56601 290 679 7.51E-97 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 Gene3D G3DSA:1.10.3810.10 91 261 3.2E-45 T 06-07-2017 CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 Pfam PF00905 Penicillin binding protein transpeptidase domain 356 617 2.2E-19 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 Gene3D G3DSA:3.40.710.10 262 653 9.0E-76 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 678 761 9.0E-15 T 06-07-2017 IPR009647 Penicillin-binding, C-terminal CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 Pfam PF00912 Transglycosylase 88 259 8.7E-44 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAL12_RS17390 f782b2b1d142c8763da569d0b8bdaf69 769 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 69 676 2.5E-225 T 06-07-2017 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SUPERFAMILY SSF55785 59 153 2.47E-9 T 06-07-2017 IPR000014 PAS domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 Pfam PF00512 His Kinase A (phospho-acceptor) domain 174 239 6.0E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 392 5.6E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SMART SM00387 284 395 3.3E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 Pfam PF13188 PAS domain 60 95 7.4E-5 T 06-07-2017 IPR000014 PAS domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 Gene3D G3DSA:3.30.565.10 243 392 7.3E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 Gene3D G3DSA:3.30.450.20 60 153 9.8E-11 T 06-07-2017 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SMART SM00091 58 124 5.9E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 340 8.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 392 8.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 373 8.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 354 8.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SUPERFAMILY SSF55874 229 394 3.41E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SUPERFAMILY SSF47384 171 240 1.9E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22290 4a2f8571298220ab7d59b9b441531f2e 405 SMART SM00388 173 242 6.0E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 Pfam PF00005 ABC transporter 23 166 3.4E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 Pfam PF08402 TOBE domain 261 333 6.9E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 SUPERFAMILY SSF50331 254 333 2.1E-6 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 SMART SM00382 32 216 1.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 Gene3D G3DSA:3.40.50.300 3 235 1.2E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00620 a02f34182f64e0dca5b8f1d15f0b82cd 338 SUPERFAMILY SSF52540 7 242 9.32E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 138 296 1.4E-39 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 SMART SM00267 127 297 5.6E-46 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 Gene3D G3DSA:3.30.70.270 141 296 6.0E-47 T 06-07-2017 CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 Pfam PF00990 Diguanylate cyclase, GGDEF domain 140 293 6.6E-39 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 SUPERFAMILY SSF55073 144 295 1.02E-41 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS02440 9c38fc740a7a4fdefedcfb65133cc5f1 299 Gene3D G3DSA:3.30.450.20 6 119 9.3E-6 T 06-07-2017 CAL12_RS17225 515766462ca73cbe9e7bb9ca39f15d90 191 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 16 179 6.4E-59 T 06-07-2017 IPR020761 Uncharacterised protein family UPF0114, bacteria CAL12_RS17225 515766462ca73cbe9e7bb9ca39f15d90 191 Pfam PF03350 Uncharacterized protein family, UPF0114 20 136 7.2E-41 T 06-07-2017 IPR005134 Uncharacterised protein family UPF0114 CAL12_RS17225 515766462ca73cbe9e7bb9ca39f15d90 191 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 184 87.035 T 06-07-2017 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 CAL12_RS21460 eb3c52de786b4d566671a1fc0896ec84 265 Gene3D G3DSA:2.40.50.100 150 183 3.6E-12 T 06-07-2017 CAL12_RS21460 eb3c52de786b4d566671a1fc0896ec84 265 Gene3D G3DSA:2.40.50.100 58 89 3.6E-12 T 06-07-2017 CAL12_RS21460 eb3c52de786b4d566671a1fc0896ec84 265 SUPERFAMILY SSF111369 46 257 1.44E-25 T 06-07-2017 CAL12_RS21460 eb3c52de786b4d566671a1fc0896ec84 265 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 257 2.0E-37 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS21460 eb3c52de786b4d566671a1fc0896ec84 265 Pfam PF13437 HlyD family secretion protein 153 244 2.0E-18 T 06-07-2017 CAL12_RS09995 6bd34be102b374fa543baf84cfd81deb 268 SUPERFAMILY SSF51621 3 253 5.42E-82 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS09995 6bd34be102b374fa543baf84cfd81deb 268 Gene3D G3DSA:3.20.20.60 4 253 5.8E-79 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS09995 6bd34be102b374fa543baf84cfd81deb 268 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 253 1.7E-122 T 06-07-2017 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 CAL12_RS09995 6bd34be102b374fa543baf84cfd81deb 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 244 5.8E-61 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAL12_RS04765 ee328850fe6d14d8217eb9aeb93af857 208 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 65 182 2.0E-13 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAL12_RS04765 ee328850fe6d14d8217eb9aeb93af857 208 SUPERFAMILY SSF51197 16 183 2.47E-32 T 06-07-2017 CAL12_RS04765 ee328850fe6d14d8217eb9aeb93af857 208 Gene3D G3DSA:2.60.120.590 16 185 4.2E-26 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Gene3D G3DSA:3.30.1490.20 133 208 1.0E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Gene3D G3DSA:3.30.470.20 209 403 2.1E-69 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Pfam PF02222 ATP-grasp domain 132 309 5.2E-51 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 SUPERFAMILY SSF52440 12 121 2.01E-32 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 22 406 3.0E-173 T 06-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Gene3D G3DSA:3.40.50.20 13 129 5.9E-39 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 SUPERFAMILY SSF51246 334 405 3.45E-18 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Pfam PF01370 NAD dependent epimerase/dehydratase family 27 89 4.5E-5 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 SUPERFAMILY SSF56059 122 328 8.84E-54 T 06-07-2017 CAL12_RS01745 23929d1272bd736e9aed5ae457d242de 411 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 16 406 51.095 T 06-07-2017 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.0E-18 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.3E-39 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 24.087 T 06-07-2017 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 SUPERFAMILY SSF55658 1 56 2.44E-16 T 06-07-2017 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 Gene3D G3DSA:3.10.430.100 60 149 7.2E-26 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 SUPERFAMILY SSF55653 60 148 5.49E-23 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 1.9E-24 T 06-07-2017 IPR020069 Ribosomal protein L9, C-terminal CAL12_RS18275 2c06dc1ee3d7198632e3f857afe02621 151 Gene3D G3DSA:3.40.5.10 1 52 7.0E-21 T 06-07-2017 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS04465 fe23053ece3253e64045f8b5acd91084 156 SMART SM00953 17 147 6.6E-17 T 06-07-2017 IPR014914 RES domain CAL12_RS04465 fe23053ece3253e64045f8b5acd91084 156 Pfam PF08808 RES domain 2 138 3.3E-16 T 06-07-2017 IPR014914 RES domain CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 SUPERFAMILY SSF48557 47 483 2.83E-79 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 Pfam PF14698 Argininosuccinate lyase C-terminal 376 458 3.4E-12 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00149 Fumarate lyase superfamily signature 115 133 1.8E-11 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00149 Fumarate lyase superfamily signature 160 178 1.8E-11 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00149 Fumarate lyase superfamily signature 246 273 1.8E-11 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00149 Fumarate lyase superfamily signature 291 307 1.8E-11 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 Gene3D G3DSA:1.10.40.30 388 458 3.6E-14 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 Gene3D G3DSA:1.20.200.10 120 387 1.1E-54 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 Pfam PF00206 Lyase 107 316 3.1E-34 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00145 Argininosuccinate lyase family signature 246 270 3.3E-23 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00145 Argininosuccinate lyase family signature 114 136 3.3E-23 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00145 Argininosuccinate lyase family signature 291 307 3.3E-23 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00145 Argininosuccinate lyase family signature 155 175 3.3E-23 T 06-07-2017 CAL12_RS12935 ca12665436ac17f8017adf9a08ea08d7 518 PRINTS PR00145 Argininosuccinate lyase family signature 206 222 3.3E-23 T 06-07-2017 CAL12_RS01105 8817f0404eaaf213ee3967149f0a6cdf 72 SMART SM00966 3 46 2.5E-6 T 06-07-2017 IPR007159 SpoVT-AbrB domain GO:0003677 CAL12_RS01105 8817f0404eaaf213ee3967149f0a6cdf 72 Gene3D G3DSA:2.10.260.10 3 57 8.8E-7 T 06-07-2017 CAL12_RS01105 8817f0404eaaf213ee3967149f0a6cdf 72 SUPERFAMILY SSF89447 2 57 3.49E-8 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 Gene3D G3DSA:3.50.50.60 121 233 2.0E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 Gene3D G3DSA:3.50.50.60 4 120 5.3E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 2.6E-118 T 06-07-2017 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 06-07-2017 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 303 3.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 Gene3D G3DSA:3.50.50.60 234 315 1.1E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.6E-39 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.6E-39 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.6E-39 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.6E-39 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.6E-39 T 06-07-2017 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 3.1E-72 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS21550 7ac28c34affd678accae51ec1432d7c9 319 SUPERFAMILY SSF51905 1 314 3.56E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 SUPERFAMILY SSF53335 89 278 1.24E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PIRSF PIRSF000410 3 281 2.5E-94 T 06-07-2017 IPR026024 Chemotaxis protein methyltransferase CheR CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 SMART SM00138 21 281 1.1E-99 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 Gene3D G3DSA:1.10.155.10 12 87 3.4E-28 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 22 74 2.8E-16 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 Gene3D G3DSA:3.40.50.150 88 278 7.5E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 115 135 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 82 94 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 149 165 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 43 56 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 221 235 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 PRINTS PR00996 Glutamate methyltransferase family signature 240 263 1.3E-45 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 SUPERFAMILY SSF47757 14 88 2.88E-21 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS11840 fc4b731949a5dabce0c17400d367c870 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 89 276 8.6E-56 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 4.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 9.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 9.0E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 Gene3D G3DSA:3.40.50.720 5 232 4.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 SUPERFAMILY SSF51735 5 232 9.27E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16465 b35d049fd16433a66f7bf0ab3a0a94a6 271 Pfam PF00106 short chain dehydrogenase 5 193 4.6E-48 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14750 08f492852065aa9dff92ef50fbc93f4d 205 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 144 1.7E-25 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS14750 08f492852065aa9dff92ef50fbc93f4d 205 Gene3D G3DSA:3.30.530.20 1 152 4.0E-39 T 06-07-2017 IPR023393 START-like domain CAL12_RS14750 08f492852065aa9dff92ef50fbc93f4d 205 SUPERFAMILY SSF55961 1 146 6.79E-27 T 06-07-2017 CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 Gene3D G3DSA:3.40.50.720 1 246 1.0E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 6.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 180 0.0077 T 06-07-2017 CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 1.9E-60 T 06-07-2017 CAL12_RS20485 2f1c6e672a9c5aa70c8ff4cf5aecb558 248 SUPERFAMILY SSF51735 4 246 3.57E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 1.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 1.4E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 SUPERFAMILY SSF48008 93 227 6.02E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 Gene3D G3DSA:1.10.10.10 18 86 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 Gene3D G3DSA:1.20.120.530 92 230 4.4E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 SMART SM00895 96 220 2.7E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 SMART SM00345 28 86 8.5E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 Pfam PF07729 FCD domain 96 219 1.4E-30 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 86 1.3E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02085 115519a26bd4e5bc6816dd1e74263fc1 237 SUPERFAMILY SSF46785 21 112 1.39E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 Pfam PF00459 Inositol monophosphatase family 21 282 1.6E-59 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 Gene3D G3DSA:3.40.190.80 178 287 5.4E-33 T 06-07-2017 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 237 251 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 Gene3D G3DSA:3.30.540.10 15 177 1.8E-49 T 06-07-2017 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 SUPERFAMILY SSF56655 14 286 1.83E-71 T 06-07-2017 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR01959 SuhB family inositol monophosphatase signature 182 208 2.6E-13 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR01959 SuhB family inositol monophosphatase signature 130 149 2.6E-13 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR01959 SuhB family inositol monophosphatase signature 224 236 2.6E-13 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 224 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 156 179 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 234 258 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS22210 3d0e4d95ab3337ca152c4f7e68794577 293 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 4.7E-51 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 SMART SM00327 85 315 6.1E-17 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 Pfam PF13519 von Willebrand factor type A domain 88 176 6.3E-18 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 Gene3D G3DSA:3.40.50.410 206 317 3.6E-9 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 Gene3D G3DSA:3.40.50.410 85 183 1.3E-13 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 Pfam PF00092 von Willebrand factor type A domain 221 314 2.2E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 SUPERFAMILY SSF53300 87 179 3.67E-30 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 SUPERFAMILY SSF53300 221 317 3.67E-30 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15400 468667dcbe90e8356f42e36c891d62ab 354 Pfam PF07584 Aerotolerance regulator N-terminal 1 75 6.9E-6 T 06-07-2017 IPR024163 Aerotolerance regulator, N-terminal CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 105 9.9E-19 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 Gene3D G3DSA:2.20.25.90 38 109 2.8E-25 T 06-07-2017 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 Pfam PF00384 Molybdopterin oxidoreductase 108 140 1.3E-4 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 Gene3D G3DSA:3.40.50.740 110 192 5.0E-13 T 06-07-2017 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 SMART SM00926 44 105 2.3E-22 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 SUPERFAMILY SSF53706 37 196 2.88E-52 T 06-07-2017 CAL12_RS19425 b0912fd6c0d5dff137181ab422530e84 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 06-07-2017 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 06-07-2017 IPR018527 Rubredoxin, iron-binding site GO:0046872 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 Pfam PF00301 Rubredoxin 4 49 6.4E-23 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 3 19 3.4E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 33 49 3.4E-8 T 06-07-2017 IPR024935 Rubredoxin domain GO:0005506 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 Gene3D G3DSA:2.20.28.10 1 53 5.8E-26 T 06-07-2017 IPR004039 Rubredoxin-type fold CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 SUPERFAMILY SSF57802 1 53 3.2E-23 T 06-07-2017 CAL12_RS24965 d4608d80a7946ea466033d1d2e351874 54 PIRSF PIRSF000071 1 54 3.3E-26 T 06-07-2017 IPR024922 Rubredoxin GO:0005506|GO:0009055 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 763 2.2E-56 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 769 847 1.8E-25 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SMART SM00382 601 770 1.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SMART SM00382 197 343 1.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 6.2E-12 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 4.3E-12 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SUPERFAMILY SSF81923 4 140 2.55E-37 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SUPERFAMILY SSF52540 158 548 1.18E-99 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 4.9E-13 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Gene3D G3DSA:3.40.50.300 554 780 1.3E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Gene3D G3DSA:1.10.8.60 781 859 1.8E-30 T 06-07-2017 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SUPERFAMILY SSF52540 550 858 1.11E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 2.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 2.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 2.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 2.2E-42 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 858 0.0 T 06-07-2017 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Gene3D G3DSA:1.10.8.60 342 427 2.9E-37 T 06-07-2017 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 SMART SM01086 769 858 3.8E-37 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Gene3D G3DSA:1.10.1780.10 1 146 1.5E-45 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS09040 046fde36fa1e01922b63118f981076cd 863 Gene3D G3DSA:3.40.50.300 159 341 2.7E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07515 1ccd6730e661827b10976d74a5fa0b81 335 PIRSF PIRSF039012 9 334 3.3E-73 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS07515 1ccd6730e661827b10976d74a5fa0b81 335 Gene3D G3DSA:3.40.630.10 32 223 7.0E-18 T 06-07-2017 CAL12_RS07515 1ccd6730e661827b10976d74a5fa0b81 335 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 44 326 2.3E-36 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS07515 1ccd6730e661827b10976d74a5fa0b81 335 SUPERFAMILY SSF53187 40 319 2.05E-42 T 06-07-2017 CAL12_RS21610 401332b174a78ca853025b0741938d70 436 Pfam PF07690 Major Facilitator Superfamily 41 397 2.3E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21610 401332b174a78ca853025b0741938d70 436 Gene3D G3DSA:1.20.1250.20 251 434 4.3E-16 T 06-07-2017 CAL12_RS21610 401332b174a78ca853025b0741938d70 436 Gene3D G3DSA:1.20.1250.20 25 235 1.8E-22 T 06-07-2017 CAL12_RS21610 401332b174a78ca853025b0741938d70 436 SUPERFAMILY SSF103473 10 434 7.85E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS17350 dbee7636d25cffd0518d7dcf7b9823d3 362 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 336 3.9E-53 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS08745 8f2029ba24010a2966dab749f74d41ae 141 Gene3D G3DSA:2.20.25.10 1 47 4.1E-25 T 06-07-2017 CAL12_RS08745 8f2029ba24010a2966dab749f74d41ae 141 SUPERFAMILY SSF82784 1 140 9.81E-47 T 06-07-2017 IPR003718 OsmC/Ohr family CAL12_RS08745 8f2029ba24010a2966dab749f74d41ae 141 Pfam PF02566 OsmC-like protein 44 138 3.5E-17 T 06-07-2017 IPR003718 OsmC/Ohr family CAL12_RS08745 8f2029ba24010a2966dab749f74d41ae 141 Gene3D G3DSA:3.30.300.20 48 140 7.0E-37 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS08745 8f2029ba24010a2966dab749f74d41ae 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 2.1E-56 T 06-07-2017 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CAL12_RS14555 400bae56f470eacc2d14b7676136794d 345 SMART SM00062 119 341 7.4E-9 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14555 400bae56f470eacc2d14b7676136794d 345 SUPERFAMILY SSF53850 120 330 5.68E-27 T 06-07-2017 CAL12_RS14555 400bae56f470eacc2d14b7676136794d 345 Gene3D G3DSA:3.40.190.10 117 223 2.1E-8 T 06-07-2017 CAL12_RS14555 400bae56f470eacc2d14b7676136794d 345 Gene3D G3DSA:3.40.190.10 224 289 4.2E-7 T 06-07-2017 CAL12_RS14555 400bae56f470eacc2d14b7676136794d 345 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 127 332 2.3E-18 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25750 c12a408bc6c69e14684a94f591e5d206 330 SUPERFAMILY SSF53850 35 323 1.11E-31 T 06-07-2017 CAL12_RS25750 c12a408bc6c69e14684a94f591e5d206 330 Gene3D G3DSA:3.40.190.10 112 222 3.2E-12 T 06-07-2017 CAL12_RS25750 c12a408bc6c69e14684a94f591e5d206 330 Pfam PF09084 NMT1/THI5 like 70 260 7.4E-13 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Gene3D G3DSA:3.20.20.70 480 823 8.5E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Gene3D G3DSA:2.160.20.60 1286 1573 1.1E-103 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Pfam PF00310 Glutamine amidotransferases class-II 41 464 7.4E-185 T 06-07-2017 IPR017932 Glutamine amidotransferase type 2 domain CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Pfam PF04898 Glutamate synthase central domain 494 773 1.3E-110 T 06-07-2017 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 SUPERFAMILY SSF69336 1280 1568 3.27E-93 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Gene3D G3DSA:3.20.20.70 881 1271 4.3E-179 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Pfam PF01493 GXGXG motif 1311 1497 2.5E-79 T 06-07-2017 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Pfam PF01645 Conserved region in glutamate synthase 834 1233 1.5E-154 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 SUPERFAMILY SSF51395 973 1267 4.03E-261 T 06-07-2017 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 SUPERFAMILY SSF51395 485 943 4.03E-261 T 06-07-2017 CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 Gene3D G3DSA:3.60.20.10 41 475 4.2E-187 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS00920 97c8a1369a0a531b066dad20fb007ac0 1579 SUPERFAMILY SSF56235 41 467 4.25E-155 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS03640 05001304c7c5b3705011b48f991fd0b2 472 Gene3D G3DSA:1.20.910.10 144 276 1.0E-7 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS03640 05001304c7c5b3705011b48f991fd0b2 472 SMART SM01236 145 242 7.9E-20 T 06-07-2017 CAL12_RS03640 05001304c7c5b3705011b48f991fd0b2 472 Pfam PF14518 Iron-containing redox enzyme 114 278 8.8E-32 T 06-07-2017 IPR028201 PqqC-like protein CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Gene3D G3DSA:3.40.50.980 166 315 2.3E-37 T 06-07-2017 CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 SUPERFAMILY SSF56801 19 497 1.57E-130 T 06-07-2017 CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Gene3D G3DSA:2.30.38.10 326 395 3.1E-13 T 06-07-2017 CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 159 170 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 411 486 1.5E-17 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Pfam PF00501 AMP-binding enzyme 19 402 2.3E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Gene3D G3DSA:3.30.300.30 397 498 9.6E-32 T 06-07-2017 CAL12_RS12970 c9b0ae164868dc63976e853802ae4bde 505 Gene3D G3DSA:3.40.50.980 20 165 4.1E-37 T 06-07-2017 CAL12_RS23010 5a7b0afb43358551fed6ab47d6dda472 267 Gene3D G3DSA:3.40.50.10320 9 216 3.7E-10 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAL12_RS23010 5a7b0afb43358551fed6ab47d6dda472 267 SUPERFAMILY SSF102588 9 212 7.59E-20 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAL12_RS23010 5a7b0afb43358551fed6ab47d6dda472 267 Pfam PF02585 GlcNAc-PI de-N-acetylase 12 143 4.0E-8 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAL12_RS21800 0f00012dcc5ce2016f988f9c7b0a766f 508 Pfam PF08666 SAF domain 14 83 2.8E-14 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS21800 0f00012dcc5ce2016f988f9c7b0a766f 508 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 505 1.4E-157 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAL12_RS21800 0f00012dcc5ce2016f988f9c7b0a766f 508 SMART SM00858 14 84 9.2E-15 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS08775 dc8ca8e1766e3279aa757c45e830b4f5 519 SUPERFAMILY SSF53822 55 393 1.82E-70 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS08775 dc8ca8e1766e3279aa757c45e830b4f5 519 Gene3D G3DSA:3.40.50.2300 309 374 8.5E-46 T 06-07-2017 CAL12_RS08775 dc8ca8e1766e3279aa757c45e830b4f5 519 Gene3D G3DSA:3.40.50.2300 54 164 8.5E-46 T 06-07-2017 CAL12_RS08775 dc8ca8e1766e3279aa757c45e830b4f5 519 Pfam PF13458 Periplasmic binding protein 56 382 8.7E-64 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 Gene3D G3DSA:1.10.10.10 121 218 1.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 Gene3D G3DSA:3.40.50.2300 1 120 6.9E-24 T 06-07-2017 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 SMART SM00448 1 116 3.6E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 215 3.7E-14 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 Pfam PF00072 Response regulator receiver domain 3 117 8.9E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 SUPERFAMILY SSF52172 1 130 3.27E-21 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 SUPERFAMILY SSF46894 152 218 6.8E-14 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 4.1E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 4.1E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 4.1E-6 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS04555 56c5c443a91353bbf9e98d2fb55f68e7 225 SMART SM00421 162 219 1.1E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SUPERFAMILY SSF54211 231 406 2.85E-56 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SMART SM00433 44 810 1.7E-259 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 ProSitePatterns PS00177 DNA topoisomerase II signature. 436 444 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SUPERFAMILY SSF56719 408 573 1.18E-82 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SUPERFAMILY SSF56719 743 808 1.18E-82 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SMART SM00387 40 186 1.5E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Gene3D G3DSA:3.30.565.10 14 228 1.7E-93 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Gene3D G3DSA:3.30.230.10 230 406 1.7E-72 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 183 6.4E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 SUPERFAMILY SSF55874 14 226 2.1E-68 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Pfam PF00204 DNA gyrase B 231 404 6.2E-59 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 817 4.7E-295 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Gene3D G3DSA:3.40.50.670 731 799 3.4E-96 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Gene3D G3DSA:3.40.50.670 418 563 3.4E-96 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Pfam PF01751 Toprim domain 433 544 3.6E-17 T 06-07-2017 IPR006171 Toprim domain CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 746 806 1.2E-29 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 206 219 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 326 342 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 484 493 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 770 782 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 256 274 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 388 408 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 14 24 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 230 252 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 191 206 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 374 388 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR01159 DNA gyrase subunit B signature 786 802 8.4E-77 T 06-07-2017 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 434 448 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 538 550 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 79 92 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 282 295 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 44 59 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 749 765 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 500 516 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 124 138 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 PRINTS PR00418 DNA topoisomerase II family signature 518 535 1.6E-68 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS00015 ba384a7dcb14a71d6f2ecf9718de6ccc 817 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 817 98.346 T 06-07-2017 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 TIGRFAM TIGR01229 rocF_arginase: arginase 7 301 5.9E-86 T 06-07-2017 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 Pfam PF00491 Arginase family 5 297 2.1E-74 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 Gene3D G3DSA:3.40.800.10 4 299 1.5E-85 T 06-07-2017 IPR023696 Ureohydrolase domain CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PIRSF PIRSF036979 2 298 1.2E-31 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 SUPERFAMILY SSF52768 6 299 3.96E-86 T 06-07-2017 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PRINTS PR00116 Arginase signature 121 148 1.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PRINTS PR00116 Arginase signature 224 253 1.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PRINTS PR00116 Arginase signature 176 194 1.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PRINTS PR00116 Arginase signature 259 273 1.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS15555 7e90029f13c2bf3b4131e7861a75ef03 305 PRINTS PR00116 Arginase signature 94 109 1.1E-43 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 SUPERFAMILY SSF53067 7 192 1.05E-48 T 06-07-2017 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 Hamap MF_00020 Acetate kinase [ackA]. 1 379 125.591 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 200 217 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 06-07-2017 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 Pfam PF00871 Acetokinase family 8 348 8.7E-90 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PRINTS PR00471 Acetate kinase family signature 319 335 6.3E-31 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PRINTS PR00471 Acetate kinase family signature 175 188 6.3E-31 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PRINTS PR00471 Acetate kinase family signature 297 310 6.3E-31 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PRINTS PR00471 Acetate kinase family signature 8 19 6.3E-31 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PRINTS PR00471 Acetate kinase family signature 200 221 6.3E-31 T 06-07-2017 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 Gene3D G3DSA:3.30.420.40 160 348 1.3E-61 T 06-07-2017 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 SUPERFAMILY SSF53067 161 375 8.57E-63 T 06-07-2017 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 PIRSF PIRSF000722 5 379 9.3E-109 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS21345 b374bc81f0b9404cddaf0eb64fab5ecd 379 TIGRFAM TIGR00016 ackA: acetate kinase 7 348 3.2E-91 T 06-07-2017 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 Pfam PF00072 Response regulator receiver domain 14 122 5.8E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 Gene3D G3DSA:3.40.50.2300 12 134 2.0E-24 T 06-07-2017 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 SUPERFAMILY SSF52172 12 135 8.82E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 SMART SM00448 10 122 3.5E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 SMART SM00862 162 238 2.7E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 Gene3D G3DSA:1.10.10.10 158 239 2.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 SUPERFAMILY SSF46894 156 239 3.12E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS09635 e0cb89b3256c4f762f61a05e98d99301 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 238 2.1E-10 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 Gene3D G3DSA:1.20.120.530 85 221 2.5E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 SUPERFAMILY SSF46785 19 107 9.09E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 80 4.7E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 SMART SM00895 92 217 2.5E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 SUPERFAMILY SSF48008 88 219 1.8E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 SMART SM00345 24 82 2.3E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 Gene3D G3DSA:1.10.10.10 13 83 8.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13000 303191bc9cf15a6e526a185533e97dd6 248 Pfam PF07729 FCD domain 92 216 6.3E-26 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS06805 f4a9dfad901422be1a974a89e9ce377c 256 SUPERFAMILY SSF56281 21 210 8.0E-35 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS06805 f4a9dfad901422be1a974a89e9ce377c 256 Gene3D G3DSA:3.60.15.10 22 209 3.7E-33 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS06805 f4a9dfad901422be1a974a89e9ce377c 256 SMART SM00849 23 208 5.2E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS06805 f4a9dfad901422be1a974a89e9ce377c 256 Pfam PF00753 Metallo-beta-lactamase superfamily 24 208 1.4E-21 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS17950 999551a32a49744f65687ef1efb2782d 338 Gene3D G3DSA:3.40.50.2000 173 301 2.7E-24 T 06-07-2017 CAL12_RS17950 999551a32a49744f65687ef1efb2782d 338 SUPERFAMILY SSF53756 9 318 9.1E-46 T 06-07-2017 CAL12_RS17950 999551a32a49744f65687ef1efb2782d 338 Gene3D G3DSA:3.40.50.2000 6 139 1.6E-20 T 06-07-2017 CAL12_RS17950 999551a32a49744f65687ef1efb2782d 338 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 81 301 2.0E-47 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS18515 a07ed6a2d042e3fad30a6f700a551f06 400 Gene3D G3DSA:1.20.1250.20 14 202 9.4E-28 T 06-07-2017 CAL12_RS18515 a07ed6a2d042e3fad30a6f700a551f06 400 Pfam PF07690 Major Facilitator Superfamily 18 231 3.7E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS18515 a07ed6a2d042e3fad30a6f700a551f06 400 SUPERFAMILY SSF103473 6 390 7.59E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS18515 a07ed6a2d042e3fad30a6f700a551f06 400 Gene3D G3DSA:1.20.1250.20 207 389 1.9E-17 T 06-07-2017 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 Gene3D G3DSA:1.10.1740.10 7 69 4.0E-14 T 06-07-2017 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 SUPERFAMILY SSF54427 169 288 1.84E-11 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 8 285 3.7E-99 T 06-07-2017 IPR014303 RNA polymerase sigma-70, ECF type CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 SUPERFAMILY SSF88946 7 68 8.63E-15 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 Gene3D G3DSA:3.10.450.50 169 283 2.9E-8 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 SUPERFAMILY SSF88659 79 162 6.73E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 Pfam PF04542 Sigma-70 region 2 7 68 5.3E-15 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 161 1.4E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 Pfam PF08281 Sigma-70, region 4 108 158 1.3E-11 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04245 244dccd2b7cd2daa7bea15ab0c420396 298 Gene3D G3DSA:1.10.10.10 107 161 2.9E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 7 313 9.6E-26 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 Gene3D G3DSA:3.40.50.720 115 282 1.9E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 SUPERFAMILY SSF52283 4 131 1.13E-26 T 06-07-2017 CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 281 1.9E-51 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 SUPERFAMILY SSF51735 97 282 4.28E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14810 66787991b35cddcff9ec18820a8c82c2 318 Gene3D G3DSA:3.40.50.720 4 114 4.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Pfam PF00072 Response regulator receiver domain 4 115 4.7E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Gene3D G3DSA:3.40.50.300 142 317 1.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Gene3D G3DSA:1.10.8.60 318 386 9.5E-21 T 06-07-2017 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Gene3D G3DSA:1.10.10.60 406 448 2.6E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Pfam PF00158 Sigma-54 interaction domain 146 311 3.6E-70 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 SUPERFAMILY SSF52540 145 384 3.62E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 SUPERFAMILY SSF52172 1 189 7.83E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Pfam PF02954 Bacterial regulatory protein, Fis family 411 449 7.0E-12 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 434 454 4.8E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 417 434 4.8E-10 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 Gene3D G3DSA:3.40.50.2300 1 123 1.5E-31 T 06-07-2017 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 SUPERFAMILY SSF46689 356 453 2.54E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 SMART SM00448 2 116 2.5E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03620 5185f831087fc1bc4ea035f124a7765e 462 SMART SM00382 165 308 8.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 Gene3D G3DSA:3.30.390.10 3 128 5.1E-34 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 22 127 1.4E-19 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 SUPERFAMILY SSF51604 115 361 5.11E-75 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 SUPERFAMILY SSF54826 4 128 1.25E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 Pfam PF13378 Enolase C-terminal domain-like 150 354 4.6E-66 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 Gene3D G3DSA:3.20.20.120 129 361 2.2E-77 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS16320 ab92cfe751b7113c9a19672cd6de2a68 367 SMART SM00922 147 244 5.9E-26 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 SUPERFAMILY SSF51569 8 295 2.72E-70 T 06-07-2017 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 5.0E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 5.0E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 5.0E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 PRINTS PR00146 Dihydrodipicolinate synthase signature 112 128 5.0E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 Pfam PF00701 Dihydrodipicolinate synthetase family 10 295 6.4E-57 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 Gene3D G3DSA:3.20.20.70 4 296 8.1E-79 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 SMART SM01130 9 297 1.9E-71 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS06170 696baeea94a13eb5a20669c6e6a923ab 305 PIRSF PIRSF001365 5 301 3.3E-64 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 Pfam PF03061 Thioesterase superfamily 23 107 3.2E-19 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 128 8.8E-33 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 PIRSF PIRSF003230 2 139 3.8E-46 T 06-07-2017 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 Gene3D G3DSA:3.10.129.10 10 139 9.8E-50 T 06-07-2017 IPR029069 HotDog domain CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 11 133 8.8E-50 T 06-07-2017 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 CAL12_RS22620 c8c7d463dd4ffb37c00e4e292009722a 140 SUPERFAMILY SSF54637 9 137 6.49E-43 T 06-07-2017 IPR029069 HotDog domain CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 SMART SM00418 56 135 1.2E-17 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 Gene3D G3DSA:1.10.10.10 51 134 1.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 91 106 5.0E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 5.0E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 106 121 5.0E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 Pfam PF12840 Helix-turn-helix domain 56 114 1.6E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03755 7b3d7dedb270ccbb5c37c4e160d63d46 268 SUPERFAMILY SSF46785 51 133 5.91E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 SUPERFAMILY SSF52374 1 156 4.02E-45 T 06-07-2017 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 1.0E-56 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 4.6E-48 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 4.6E-48 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 4.6E-48 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 4.6E-48 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 4.6E-48 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 Pfam PF01467 Cytidylyltransferase-like 5 133 2.6E-20 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 57 5.0E-16 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 Gene3D G3DSA:3.40.50.620 2 160 9.8E-55 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS02940 3c24ed056e60e12664fdaf8d58f61237 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.275 T 06-07-2017 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 Pfam PF02049 Flagellar hook-basal body complex protein FliE 34 118 1.1E-24 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 40 116 4.7E-20 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 7 118 16.074 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 103 116 1.9E-12 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 82 98 1.9E-12 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS12030 a28cacb0b4e7a954c93a034b65cb4ae6 118 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 47 63 1.9E-12 T 06-07-2017 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Pfam PF00873 AcrB/AcrD/AcrF family 4 1039 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.7E-66 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82714 735 817 2.09E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:3.30.70.1430 40 141 2.8E-30 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:3.30.70.1430 585 675 7.0E-10 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82693 136 182 1.15E-23 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82693 268 324 1.15E-23 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:3.30.2090.10 735 818 3.2E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82714 183 266 3.4E-15 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:3.30.2090.10 183 265 9.6E-17 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:1.10.3850.10 824 1041 1.1E-56 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82693 582 679 1.67E-15 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82866 823 1042 7.19E-48 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82693 40 134 1.33E-23 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 SUPERFAMILY SSF82866 290 490 1.44E-46 T 06-07-2017 CAL12_RS25100 c4e5635d414d04f29d507b59ad0ac6b4 1059 Gene3D G3DSA:1.20.1640.10 285 498 6.6E-58 T 06-07-2017 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 616 693 2.4E-13 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 41 203 1.7E-9 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 342 575 2.5E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Gene3D G3DSA:3.30.365.10 56 209 1.6E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Gene3D G3DSA:3.30.365.10 413 575 5.4E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 PIRSF PIRSF036389 15 752 1.6E-241 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 SUPERFAMILY SSF56003 37 259 1.74E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 SMART SM01008 230 309 5.6E-17 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Gene3D G3DSA:3.30.365.10 576 746 1.5E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 SUPERFAMILY SSF56003 342 746 3.72E-96 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21195 dc7a8513e8e5eff825aba361ac1784e7 752 Gene3D G3DSA:3.90.1170.50 210 307 3.7E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 PIRSF PIRSF000077 2 108 9.6E-45 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 Pfam PF00085 Thioredoxin 5 105 4.6E-35 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 Gene3D G3DSA:3.40.30.10 2 106 5.9E-40 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 SUPERFAMILY SSF52833 2 108 2.36E-41 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 PRINTS PR00421 Thioredoxin family signature 32 41 7.7E-10 T 06-07-2017 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 PRINTS PR00421 Thioredoxin family signature 24 32 7.7E-10 T 06-07-2017 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 PRINTS PR00421 Thioredoxin family signature 72 83 7.7E-10 T 06-07-2017 CAL12_RS09070 92208916265e4169aa098c30ca2d0f08 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 106 6.3E-40 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 4.7E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 Gene3D G3DSA:3.40.50.720 1 244 4.6E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 2.2E-59 T 06-07-2017 CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16795 25cb352eb6e1196ea49bb77b9e64377d 246 SUPERFAMILY SSF51735 1 245 1.24E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 SUPERFAMILY SSF54826 1 130 2.69E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 Gene3D G3DSA:3.20.20.120 132 372 2.0E-69 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 SUPERFAMILY SSF51604 118 373 2.23E-63 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 20 128 2.6E-15 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 SMART SM00922 148 244 1.1E-18 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 Pfam PF13378 Enolase C-terminal domain-like 152 365 7.7E-55 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS14815 b5ea2c62a3f7035509408243ac08d2bd 380 Gene3D G3DSA:3.30.390.10 1 131 5.2E-34 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00770 0245f77dd322b6f8437d336239834107 258 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 9 245 6.4E-52 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAL12_RS00770 0245f77dd322b6f8437d336239834107 258 Gene3D G3DSA:3.40.1390.30 111 225 1.4E-28 T 06-07-2017 CAL12_RS00770 0245f77dd322b6f8437d336239834107 258 Gene3D G3DSA:3.40.1390.30 7 110 5.3E-34 T 06-07-2017 CAL12_RS00770 0245f77dd322b6f8437d336239834107 258 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 7 257 6.0E-53 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAL12_RS00770 0245f77dd322b6f8437d336239834107 258 SUPERFAMILY SSF102705 6 257 1.26E-72 T 06-07-2017 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 SUPERFAMILY SSF52172 53 212 2.42E-33 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 SMART SM00421 187 244 2.1E-23 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 189 244 3.7E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 SMART SM00448 51 163 7.4E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 Gene3D G3DSA:3.40.50.2300 53 189 3.1E-34 T 06-07-2017 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 Gene3D G3DSA:1.10.10.10 190 248 2.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 Pfam PF00072 Response regulator receiver domain 53 163 8.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 204 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 220 232 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22285 ab08b27afeb904e50f770de7f1d65640 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 204 220 1.2E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 Pfam PF13305 WHG domain 105 188 8.7E-14 T 06-07-2017 IPR025996 WHG domain CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 SUPERFAMILY SSF46689 19 90 3.94E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 Gene3D G3DSA:1.10.357.10 78 213 2.8E-17 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 6.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 Gene3D G3DSA:1.10.10.60 16 77 2.1E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS14855 69ef1265c184ca1faed81641e594ff12 256 SUPERFAMILY SSF48498 104 211 8.67E-18 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 2.1E-4 T 06-07-2017 CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 Pfam PF00106 short chain dehydrogenase 6 191 2.3E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 SUPERFAMILY SSF51735 1 219 3.95E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.7E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16635 3efaa0ea5c540166b400297816a40608 251 Gene3D G3DSA:3.40.50.720 2 196 6.3E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 Gene3D G3DSA:3.40.50.720 9 241 3.4E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 SUPERFAMILY SSF51735 9 240 8.72E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 Pfam PF00106 short chain dehydrogenase 12 194 6.6E-54 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01595 409bc08aab6d5923530f14a19aeba74a 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:1.10.287.560 349 408 2.0E-8 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SMART SM00260 586 718 1.7E-28 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:3.30.565.10 409 593 2.0E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:2.30.30.40 594 615 2.2E-19 T 06-07-2017 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:2.30.30.40 674 718 2.2E-19 T 06-07-2017 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SMART SM00073 3 100 3.5E-25 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SUPERFAMILY SSF55874 410 592 2.38E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SUPERFAMILY SSF50341 593 718 4.05E-29 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 593 8.8E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SMART SM01231 348 408 2.3E-9 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Pfam PF01584 CheW-like domain 600 720 5.8E-23 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 512 7.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 554 572 7.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 578 591 7.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 538 548 7.2E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 349 402 2.2E-5 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SUPERFAMILY SSF47384 349 409 4.32E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:1.20.120.160 1 142 8.6E-37 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Gene3D G3DSA:2.40.50.180 624 673 5.0E-14 T 06-07-2017 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 Pfam PF01627 Hpt domain 6 92 1.8E-19 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SUPERFAMILY SSF47226 2 122 6.41E-28 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SMART SM00387 453 594 2.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23740 54344c39d48046d3dd8d2b90265d4813 734 SUPERFAMILY SSF160246 284 338 1.07E-5 T 06-07-2017 CAL12_RS23175 6e439ad2deba2aa0af66e67d8c0df23d 439 Gene3D G3DSA:1.20.1250.20 28 208 6.2E-13 T 06-07-2017 CAL12_RS23175 6e439ad2deba2aa0af66e67d8c0df23d 439 SUPERFAMILY SSF103473 24 432 1.31E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23175 6e439ad2deba2aa0af66e67d8c0df23d 439 Gene3D G3DSA:1.20.1250.20 251 426 2.7E-10 T 06-07-2017 CAL12_RS23175 6e439ad2deba2aa0af66e67d8c0df23d 439 Pfam PF07690 Major Facilitator Superfamily 33 396 2.9E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21560 74570ba2cae052175039d6b0bebc12ea 313 SUPERFAMILY SSF53850 93 274 3.4E-10 T 06-07-2017 CAL12_RS21560 74570ba2cae052175039d6b0bebc12ea 313 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 36 309 1.6E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21560 74570ba2cae052175039d6b0bebc12ea 313 PIRSF PIRSF017082 1 313 6.0E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15665 20c4c5fb63a047b598129972eaf78062 295 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15665 20c4c5fb63a047b598129972eaf78062 295 SUPERFAMILY SSF52540 39 254 7.7E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15665 20c4c5fb63a047b598129972eaf78062 295 SMART SM00382 73 253 4.9E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15665 20c4c5fb63a047b598129972eaf78062 295 Gene3D G3DSA:3.40.50.300 30 256 1.1E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15665 20c4c5fb63a047b598129972eaf78062 295 Pfam PF00005 ABC transporter 64 203 2.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08010 38d12020b58179dc204489874eee1561 468 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 22 468 9.2E-142 T 06-07-2017 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CAL12_RS08010 38d12020b58179dc204489874eee1561 468 SUPERFAMILY SSF51735 147 245 5.33E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08010 38d12020b58179dc204489874eee1561 468 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 25 468 1.7E-157 T 06-07-2017 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 CAL12_RS08010 38d12020b58179dc204489874eee1561 468 Pfam PF02397 Bacterial sugar transferase 278 459 8.9E-58 T 06-07-2017 IPR003362 Bacterial sugar transferase CAL12_RS08010 38d12020b58179dc204489874eee1561 468 Gene3D G3DSA:3.40.50.720 147 222 8.2E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08010 38d12020b58179dc204489874eee1561 468 Pfam PF13727 CoA-binding domain 67 242 2.7E-33 T 06-07-2017 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 396 546 3.7E-26 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 Pfam PF06826 Predicted Permease Membrane Region 391 560 3.7E-41 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 Pfam PF06826 Predicted Permease Membrane Region 15 177 5.6E-37 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 Pfam PF02080 TrkA-C domain 227 277 8.1E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 SUPERFAMILY SSF116726 211 280 1.96E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 2 562 1.7E-199 T 06-07-2017 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 Gene3D G3DSA:3.30.70.1450 307 377 3.2E-6 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 Gene3D G3DSA:3.30.70.1450 225 278 5.3E-7 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS18985 00968c385a2ad73c8b0bf53fa7323c3a 563 SUPERFAMILY SSF116726 292 377 2.22E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 393 2.0E-14 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 SUPERFAMILY SSF57716 13 48 3.85E-11 T 06-07-2017 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 309 3.0E-47 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 SUPERFAMILY SSF52540 62 403 4.45E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Gene3D G3DSA:3.40.50.300 65 254 2.3E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Gene3D G3DSA:3.40.50.300 293 310 2.3E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 3.3E-198 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Gene3D G3DSA:1.10.8.60 315 415 3.3E-33 T 06-07-2017 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 SMART SM00382 112 332 4.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Pfam PF06689 ClpX C4-type zinc finger 13 50 1.4E-19 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 SMART SM00994 12 51 1.7E-23 T 06-07-2017 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 SMART SM01086 316 411 3.1E-31 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS17210 b3275ec399507ee32b792529bf48f3c4 432 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 6 414 52.316 T 06-07-2017 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 PRINTS PR01021 OMPA domain signature 103 119 7.9E-14 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 PRINTS PR01021 OMPA domain signature 88 103 7.9E-14 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 PRINTS PR01021 OMPA domain signature 58 80 7.9E-14 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 SUPERFAMILY SSF103088 44 158 9.42E-34 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 Gene3D G3DSA:3.30.1330.60 40 158 1.2E-34 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS05180 4e9c9460a21938dd24fa7b19f0db5efb 161 Pfam PF00691 OmpA family 57 152 8.7E-20 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 SUPERFAMILY SSF53850 90 297 9.59E-40 T 06-07-2017 CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 Gene3D G3DSA:3.40.190.10 92 176 3.0E-18 T 06-07-2017 CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 Gene3D G3DSA:3.40.190.10 177 264 3.5E-13 T 06-07-2017 CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.3E-12 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 Gene3D G3DSA:1.10.10.10 3 88 3.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 SUPERFAMILY SSF46785 1 112 1.16E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12610 759dd1fd657a6d29058c324b64e5f49a 299 Pfam PF03466 LysR substrate binding domain 89 294 1.5E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS17690 d1b77c1fa4ef2b5521c8954526db5bdd 438 Pfam PF03781 Sulfatase-modifying factor enzyme 1 195 436 4.0E-34 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAL12_RS17690 d1b77c1fa4ef2b5521c8954526db5bdd 438 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 21 435 7.6E-172 T 06-07-2017 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 CAL12_RS17690 d1b77c1fa4ef2b5521c8954526db5bdd 438 Pfam PF12867 DinB superfamily 24 157 3.5E-12 T 06-07-2017 IPR024775 DinB-like domain CAL12_RS17690 d1b77c1fa4ef2b5521c8954526db5bdd 438 Gene3D G3DSA:3.90.1580.10 189 437 3.7E-63 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAL12_RS17690 d1b77c1fa4ef2b5521c8954526db5bdd 438 SUPERFAMILY SSF56436 192 437 1.86E-72 T 06-07-2017 IPR016187 C-type lectin fold CAL12_RS00950 e6a6756e46950f776e3b8886acb5b86a 326 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 44 285 36.174 T 06-07-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CAL12_RS00950 e6a6756e46950f776e3b8886acb5b86a 326 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 230 282 4.0E-16 T 06-07-2017 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 CAL12_RS00950 e6a6756e46950f776e3b8886acb5b86a 326 SUPERFAMILY SSF56300 46 292 2.47E-48 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS00950 e6a6756e46950f776e3b8886acb5b86a 326 Pfam PF00149 Calcineurin-like phosphoesterase 46 231 3.3E-13 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS00950 e6a6756e46950f776e3b8886acb5b86a 326 Gene3D G3DSA:3.60.21.10 46 279 2.6E-29 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 Pfam PF02308 MgtC family 32 156 2.6E-41 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 SUPERFAMILY SSF103473 30 147 6.54E-5 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 PRINTS PR01837 MgtC/SapB protein signature 81 103 1.4E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 PRINTS PR01837 MgtC/SapB protein signature 110 134 1.4E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 PRINTS PR01837 MgtC/SapB protein signature 35 54 1.4E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAL12_RS22750 7ab2cc2c7c4de6ff223ed075b90c0421 173 PRINTS PR01837 MgtC/SapB protein signature 54 72 1.4E-42 T 06-07-2017 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 SUPERFAMILY SSF46785 2 73 3.85E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 SMART SM00346 2 91 7.6E-22 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 Pfam PF09339 IclR helix-turn-helix domain 4 54 2.4E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 Gene3D G3DSA:1.10.10.10 2 70 1.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 Pfam PF01614 Bacterial transcriptional regulator 120 244 3.7E-25 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 SUPERFAMILY SSF55781 68 245 1.57E-44 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS23800 0ea5ddb15b2d0ff426c92a648033da49 247 Gene3D G3DSA:3.30.450.40 71 245 1.2E-46 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Pfam PF00005 ABC transporter 27 190 2.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Pfam PF00005 ABC transporter 342 491 7.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Gene3D G3DSA:3.40.50.300 313 566 1.1E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Gene3D G3DSA:3.40.50.300 6 264 8.2E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 SMART SM00382 350 542 8.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 SMART SM00382 35 240 1.4E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 SUPERFAMILY SSF52540 315 564 6.12E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 SUPERFAMILY SSF52540 7 262 4.99E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 544 576 5.2E-9 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15905 6fed3d4363e23af0d89c3367c04dd9ba 623 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 271 1.8E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 141 5.0E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 6.7E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 Gene3D G3DSA:1.10.10.10 2 52 8.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 SUPERFAMILY SSF54909 64 150 3.22E-21 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 SUPERFAMILY SSF46785 1 60 6.23E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 SMART SM00344 1 110 3.4E-40 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.3E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.3E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.3E-14 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS19960 4fd6a1b9ab93a0fe8d275ec24784397f 150 Gene3D G3DSA:3.30.70.920 54 150 3.1E-28 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS23405 2a57d2751b6db2a5c0601b4ee3ff074c 335 SUPERFAMILY SSF53850 115 286 7.36E-12 T 06-07-2017 CAL12_RS23405 2a57d2751b6db2a5c0601b4ee3ff074c 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 331 2.8E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23405 2a57d2751b6db2a5c0601b4ee3ff074c 335 PIRSF PIRSF017082 1 334 3.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 SUPERFAMILY SSF51735 15 314 2.24E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 Pfam PF00535 Glycosyl transferase family 2 338 496 9.3E-24 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 Pfam PF01370 NAD dependent epimerase/dehydratase family 15 245 4.6E-44 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 Gene3D G3DSA:3.90.25.10 194 316 9.7E-26 T 06-07-2017 CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 SUPERFAMILY SSF53448 335 551 2.51E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 Gene3D G3DSA:3.40.50.720 15 193 1.8E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26865 a38bad01172cafe6aab44fef773a6784 650 Gene3D G3DSA:3.90.550.10 336 458 2.7E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Gene3D G3DSA:3.40.47.10 201 282 7.8E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Gene3D G3DSA:3.40.47.10 5 126 7.8E-66 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 1.1E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 1.4E-132 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 SUPERFAMILY SSF53901 5 276 5.03E-78 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 4 401 7.4E-216 T 06-07-2017 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Gene3D G3DSA:3.40.47.10 154 200 3.0E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Gene3D G3DSA:3.40.47.10 283 400 3.0E-58 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 Pfam PF00108 Thiolase, N-terminal domain 6 267 7.1E-72 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 PIRSF PIRSF000429 1 401 2.5E-130 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS17415 edc423b0bf0378af70a2036b2414a1ed 401 SUPERFAMILY SSF53901 277 400 1.0E-45 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS20710 1511577f19057ce9c972438bf2672ae2 323 SUPERFAMILY SSF53850 72 281 4.13E-10 T 06-07-2017 CAL12_RS20710 1511577f19057ce9c972438bf2672ae2 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 1.6E-62 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20710 1511577f19057ce9c972438bf2672ae2 323 PIRSF PIRSF017082 1 323 3.5E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Gene3D G3DSA:2.20.200.10 108 149 1.4E-22 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Gene3D G3DSA:2.20.200.10 327 362 1.4E-22 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 SUPERFAMILY SSF56954 3 32 1.07E-117 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 SUPERFAMILY SSF56954 63 480 1.07E-117 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Pfam PF02321 Outer membrane efflux protein 294 475 6.7E-31 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Pfam PF02321 Outer membrane efflux protein 72 262 7.9E-31 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Gene3D G3DSA:1.20.1600.10 150 326 2.1E-106 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Gene3D G3DSA:1.20.1600.10 364 478 2.1E-106 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 Gene3D G3DSA:1.20.1600.10 61 98 2.1E-106 T 06-07-2017 CAL12_RS15770 ef35f62022050a0be620aed1b831b520 501 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 12 477 5.4E-129 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 SMART SM00919 164 401 1.2E-139 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 4.5E-24 T 06-07-2017 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 751 4.5E-97 T 06-07-2017 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 SUPERFAMILY SSF53659 430 754 2.96E-90 T 06-07-2017 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 PIRSF PIRSF036684 1 759 0.0 T 06-07-2017 IPR012188 Malic enzyme, phosphate acetyl/butaryl transferase GO:0004473|GO:0005829|GO:0006108|GO:0016616|GO:0030145|GO:0046872|GO:0055114 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 SMART SM01274 18 152 3.8E-77 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Gene3D G3DSA:3.40.50.10380 10 161 5.4E-48 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Pfam PF00390 Malic enzyme, N-terminal domain 115 152 5.3E-5 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Pfam PF00390 Malic enzyme, N-terminal domain 19 113 1.3E-21 T 06-07-2017 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Gene3D G3DSA:3.40.50.720 162 449 9.4E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 SUPERFAMILY SSF53223 11 162 1.65E-49 T 06-07-2017 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 Gene3D G3DSA:3.40.50.10750 569 726 7.3E-54 T 06-07-2017 CAL12_RS19230 52d2ad44e840283fb02752ccabe5d7b2 765 SUPERFAMILY SSF51735 164 443 7.89E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 Gene3D G3DSA:1.10.3430.10 2 391 1.5E-133 T 06-07-2017 IPR029020 Ammonium/urea transporter CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 TIGRFAM TIGR00836 amt: ammonium transporter 5 410 4.2E-130 T 06-07-2017 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 SUPERFAMILY SSF111352 2 391 5.49E-124 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 Pfam PF00909 Ammonium Transporter Family 8 410 1.0E-117 T 06-07-2017 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 06-07-2017 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 PRINTS PR00342 Rhesus blood group protein signature 291 309 8.3E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 PRINTS PR00342 Rhesus blood group protein signature 205 223 8.3E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 PRINTS PR00342 Rhesus blood group protein signature 105 121 8.3E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAL12_RS09870 d50674f7b76e8fc79a2f3350e2774224 412 PRINTS PR00342 Rhesus blood group protein signature 236 258 8.3E-6 T 06-07-2017 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 Gene3D G3DSA:3.30.190.20 161 226 8.8E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 Gene3D G3DSA:3.30.190.20 16 68 8.8E-45 T 06-07-2017 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 SUPERFAMILY SSF56808 7 225 6.41E-81 T 06-07-2017 IPR023674 Ribosomal protein L1-like CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.9E-103 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.674 T 06-07-2017 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 Gene3D G3DSA:3.40.50.790 69 159 2.9E-41 T 06-07-2017 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 06-07-2017 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 PIRSF PIRSF002155 1 227 7.1E-78 T 06-07-2017 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27765 3bdcb479078aa331742340d3d58e8efe 234 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 2.7E-50 T 06-07-2017 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CAL12_RS00080 77b5aa74ad885c09972dda9f83cfd8b3 295 SUPERFAMILY SSF51197 1 287 2.15E-72 T 06-07-2017 CAL12_RS00080 77b5aa74ad885c09972dda9f83cfd8b3 295 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 279 1.8E-59 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS00080 77b5aa74ad885c09972dda9f83cfd8b3 295 Gene3D G3DSA:3.60.130.10 2 287 4.4E-76 T 06-07-2017 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 Gene3D G3DSA:3.10.20.30 222 327 1.6E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 Gene3D G3DSA:2.40.30.10 10 105 1.0E-29 T 06-07-2017 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 253 321 1.3E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 SUPERFAMILY SSF52343 102 228 2.49E-22 T 06-07-2017 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 Gene3D G3DSA:3.40.50.80 112 221 1.1E-20 T 06-07-2017 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 280 288 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 56 70 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 94 108 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 34 44 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 80 94 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 195 203 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 PRINTS PR00409 Phthalate dioxygenase reductase family signature 44 56 6.0E-34 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 SUPERFAMILY SSF54292 217 329 1.06E-18 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS24510 7c3012785efe0cb236e567c4804adfcc 329 SUPERFAMILY SSF63380 10 104 3.16E-24 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 Gene3D G3DSA:3.50.50.60 211 338 1.1E-126 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 Gene3D G3DSA:3.50.50.60 27 150 1.1E-126 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 Gene3D G3DSA:3.50.50.60 491 557 1.1E-126 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 Pfam PF00732 GMC oxidoreductase 29 320 1.1E-80 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 106 129 - T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 SUPERFAMILY SSF51905 26 313 4.17E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 SUPERFAMILY SSF51905 497 556 4.17E-92 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 PIRSF PIRSF000137 11 563 6.8E-153 T 06-07-2017 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 SUPERFAMILY SSF54373 315 498 2.45E-59 T 06-07-2017 CAL12_RS27090 310085e8320cdc55f382872034a58cb0 576 Pfam PF05199 GMC oxidoreductase 412 547 6.4E-38 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Gene3D G3DSA:3.40.50.970 352 556 1.8E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 SUPERFAMILY SSF52518 369 564 9.47E-66 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 SUPERFAMILY SSF52467 187 359 6.18E-64 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 6.8E-46 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 SUPERFAMILY SSF52518 2 176 3.83E-65 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Gene3D G3DSA:3.40.50.970 2 175 1.4E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 169 5.0E-60 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Gene3D G3DSA:3.40.50.1220 188 351 5.8E-65 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 540 9.8E-48 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS20945 b9194812fa7eddef2dd1acf5ea73f798 569 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 563 1.5E-246 T 06-07-2017 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 Gene3D G3DSA:3.40.190.10 193 260 4.2E-12 T 06-07-2017 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 SUPERFAMILY SSF46785 1 109 2.32E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 SUPERFAMILY SSF53850 88 296 1.03E-34 T 06-07-2017 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.1E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 Gene3D G3DSA:3.40.190.10 82 192 4.9E-23 T 06-07-2017 CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 Gene3D G3DSA:1.10.10.10 1 81 2.5E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14685 0ea5986d5f878413178d208f42f7bbfb 322 Pfam PF03466 LysR substrate binding domain 87 291 2.0E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 SMART SM00895 86 215 9.9E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 Pfam PF07729 FCD domain 87 214 2.2E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 SMART SM00345 18 76 1.6E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 SUPERFAMILY SSF46785 12 80 3.07E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 Gene3D G3DSA:1.10.10.10 16 76 3.1E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 Gene3D G3DSA:1.20.120.530 79 220 8.6E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 76 1.4E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10500 f77b32cab027e62520eafd2190012659 257 SUPERFAMILY SSF48008 82 219 1.46E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Pfam PF14450 Cell division protein FtsA 206 373 1.5E-25 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Pfam PF14450 Cell division protein FtsA 10 193 5.6E-10 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 SMART SM00842 9 195 3.0E-107 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.9E-32 T 06-07-2017 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 SUPERFAMILY SSF53067 198 375 3.27E-47 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 376 2.3E-147 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.90.640.10 234 296 1.3E-17 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.30.1490.110 85 156 8.5E-17 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.30.420.40 297 350 1.9E-33 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.30.420.40 209 233 1.9E-33 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 406 30.551 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 PIRSF PIRSF003101 1 408 1.5E-151 T 06-07-2017 IPR020823 Cell division protein FtsA GO:0007049 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.30.420.40 157 208 1.5E-24 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 Gene3D G3DSA:3.30.420.40 5 82 1.5E-24 T 06-07-2017 CAL12_RS22390 322d2c975a821e09fcb40eea0c7bcb4c 408 SUPERFAMILY SSF53067 7 196 3.37E-63 T 06-07-2017 CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 SUPERFAMILY SSF54211 143 281 1.9E-51 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 2.2E-105 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3 301 3.6E-118 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 Gene3D G3DSA:3.30.1700.10 128 286 2.3E-60 T 06-07-2017 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 Gene3D G3DSA:3.30.230.20 3 125 1.0E-42 T 06-07-2017 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 SUPERFAMILY SSF54211 3 125 7.59E-41 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS22380 4a1703a27daee34b6f04b2a1ce0427c8 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 45.342 T 06-07-2017 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 160 329 7.3E-43 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 Gene3D G3DSA:3.40.50.720 169 329 5.6E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 SUPERFAMILY SSF52283 75 183 5.39E-5 T 06-07-2017 CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 268 284 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 SUPERFAMILY SSF51735 151 329 6.78E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13425 1893014adfe7bc3af5f3d89108c6c054 364 Gene3D G3DSA:3.40.50.720 70 168 3.7E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08700 e6b6c0925767a9f597a3fbebe882184f 339 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 327 1.2E-87 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS08700 e6b6c0925767a9f597a3fbebe882184f 339 SMART SM00797 23 319 1.0E-135 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS08700 e6b6c0925767a9f597a3fbebe882184f 339 Pfam PF02626 Allophanate hydrolase subunit 2 24 302 4.3E-89 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS08700 e6b6c0925767a9f597a3fbebe882184f 339 SUPERFAMILY SSF50891 197 309 9.1E-8 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS08700 e6b6c0925767a9f597a3fbebe882184f 339 Gene3D G3DSA:2.40.100.10 249 313 2.8E-4 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 Gene3D G3DSA:2.30.38.10 437 498 2.2E-17 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 SUPERFAMILY SSF56801 580 641 1.16E-111 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 SUPERFAMILY SSF56801 32 322 1.16E-111 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 SUPERFAMILY SSF56801 374 553 1.16E-111 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 ProSitePatterns PS00455 Putative AMP-binding domain signature. 219 230 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 Pfam PF00501 AMP-binding enzyme 51 504 9.7E-89 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 Gene3D G3DSA:3.40.50.980 37 225 1.3E-34 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 Gene3D G3DSA:3.40.50.980 226 317 2.1E-25 T 06-07-2017 CAL12_RS26435 e09110be2ec91a1a31413a2ed70abc20 680 Gene3D G3DSA:3.40.50.980 371 435 2.1E-25 T 06-07-2017 CAL12_RS26055 1e8595757c789614bedd537985aba792 87 SUPERFAMILY SSF160272 5 71 2.75E-7 T 06-07-2017 IPR009962 Protein of unknown function DUF1488 CAL12_RS26055 1e8595757c789614bedd537985aba792 87 Pfam PF07369 Protein of unknown function (DUF1488) 4 71 6.0E-9 T 06-07-2017 IPR009962 Protein of unknown function DUF1488 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 Pfam PF01926 50S ribosome-binding GTPase 161 289 7.4E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 336 1.1E-139 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 Hamap MF_01454 GTPase Obg [obg]. 2 338 47.357 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 Gene3D G3DSA:2.70.210.12 2 156 6.0E-59 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 SUPERFAMILY SSF82051 2 158 7.32E-56 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.9E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 Gene3D G3DSA:3.40.50.300 160 351 1.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 SUPERFAMILY SSF52540 150 341 2.79E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 06-07-2017 IPR006074 GTP1/OBG, conserved site GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 PIRSF PIRSF002401 1 370 2.2E-133 T 06-07-2017 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CAL12_RS01775 ab26e1420dc1b2772ac37cbefb5fceb0 376 Pfam PF01018 GTP1/OBG 3 158 4.0E-60 T 06-07-2017 IPR006169 GTP1/OBG domain GO:0005525 CAL12_RS10835 028f2c9350257e8cd283b1a8d7665c7d 323 PIRSF PIRSF036979 15 317 2.4E-47 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS10835 028f2c9350257e8cd283b1a8d7665c7d 323 SUPERFAMILY SSF52768 9 314 7.02E-61 T 06-07-2017 CAL12_RS10835 028f2c9350257e8cd283b1a8d7665c7d 323 Pfam PF00491 Arginase family 31 310 1.8E-56 T 06-07-2017 IPR006035 Ureohydrolase GO:0046872 CAL12_RS10835 028f2c9350257e8cd283b1a8d7665c7d 323 Gene3D G3DSA:3.40.800.10 5 316 4.4E-69 T 06-07-2017 IPR023696 Ureohydrolase domain CAL12_RS11755 925ade2ee590ee7a9c70cce560662b28 254 Pfam PF04989 Cephalosporin hydroxylase 45 254 2.0E-73 T 06-07-2017 IPR007072 Rhamnosyl O-methyltransferase/Cephalosporin hydroxylase GO:0008168|GO:0008610 CAL12_RS11755 925ade2ee590ee7a9c70cce560662b28 254 Gene3D G3DSA:3.40.50.150 53 213 4.1E-12 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS11755 925ade2ee590ee7a9c70cce560662b28 254 SUPERFAMILY SSF53335 29 254 2.82E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 Gene3D G3DSA:3.20.20.140 162 266 3.2E-39 T 06-07-2017 CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 Gene3D G3DSA:3.20.20.140 9 92 3.2E-39 T 06-07-2017 CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 SUPERFAMILY SSF89550 170 281 3.34E-48 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 SUPERFAMILY SSF89550 8 87 3.34E-48 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 Pfam PF02811 PHP domain 10 91 3.9E-9 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAL12_RS17075 c343a0103df25db93914e61f66d6d345 282 SMART SM00481 9 74 8.9E-20 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 5.3E-138 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Pfam PF00108 Thiolase, N-terminal domain 4 262 4.7E-90 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 PIRSF PIRSF000429 1 393 4.6E-125 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Gene3D G3DSA:3.40.47.10 194 275 2.5E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Gene3D G3DSA:3.40.47.10 3 124 2.5E-65 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 SUPERFAMILY SSF53901 4 269 6.45E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Gene3D G3DSA:3.40.47.10 277 392 1.6E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Gene3D G3DSA:3.40.47.10 143 193 1.6E-64 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 SUPERFAMILY SSF53901 271 392 4.98E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08805 d88974929b6d8529273b4183d6fb3e4e 393 Pfam PF02803 Thiolase, C-terminal domain 271 392 2.6E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS07820 1d5d12eff1830bbca5ffbe4f1fc858fe 115 Gene3D G3DSA:1.20.950.10 12 112 6.8E-12 T 06-07-2017 CAL12_RS07820 1d5d12eff1830bbca5ffbe4f1fc858fe 115 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 5 102 5.0E-7 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07820 1d5d12eff1830bbca5ffbe4f1fc858fe 115 SUPERFAMILY SSF81343 12 113 1.0E-14 T 06-07-2017 CAL12_RS24090 d25dd9355e7c2acd627c2ddc9bb31e51 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 304 4.8E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24090 d25dd9355e7c2acd627c2ddc9bb31e51 308 SUPERFAMILY SSF161098 102 288 4.06E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24090 d25dd9355e7c2acd627c2ddc9bb31e51 308 Gene3D G3DSA:1.10.3720.10 101 302 5.6E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24090 d25dd9355e7c2acd627c2ddc9bb31e51 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 36 82 1.1E-5 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS09215 856c61317f96ec7553833f4d56987245 154 Pfam PF13413 Helix-turn-helix domain 17 76 7.2E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS09215 856c61317f96ec7553833f4d56987245 154 SMART SM00530 16 77 0.0052 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS09215 856c61317f96ec7553833f4d56987245 154 SUPERFAMILY SSF47413 12 78 1.66E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS09215 856c61317f96ec7553833f4d56987245 154 Gene3D G3DSA:1.10.260.40 10 81 6.2E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 Gene3D G3DSA:3.40.190.10 93 178 4.1E-28 T 06-07-2017 CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 Gene3D G3DSA:3.40.190.10 179 257 2.2E-23 T 06-07-2017 CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 SUPERFAMILY SSF46785 4 112 3.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 Pfam PF03466 LysR substrate binding domain 89 293 5.3E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.7E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 Gene3D G3DSA:1.10.10.10 3 84 4.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10745 909d661c7a381db35fcbbc38a791a8d3 298 SUPERFAMILY SSF53850 91 295 1.09E-46 T 06-07-2017 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 SUPERFAMILY SSF52317 16 212 8.13E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 Gene3D G3DSA:1.10.10.60 234 283 1.8E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 Pfam PF12833 Helix-turn-helix domain 253 332 6.7E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 284 326 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 SUPERFAMILY SSF46689 283 334 1.57E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 Pfam PF01965 DJ-1/PfpI family 17 191 9.7E-20 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 SMART SM00342 247 330 2.2E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 SUPERFAMILY SSF46689 231 280 3.31E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 Gene3D G3DSA:3.40.50.880 18 233 3.8E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS03400 dce6a25fbb8093f76e33c76c75db0e7c 340 Gene3D G3DSA:1.10.10.60 284 330 3.2E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17170 5fa31a032e64c64f1e63b2909c039c71 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 2.8E-69 T 06-07-2017 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAL12_RS17170 5fa31a032e64c64f1e63b2909c039c71 128 Gene3D G3DSA:3.90.1010.10 2 126 3.5E-57 T 06-07-2017 CAL12_RS17170 5fa31a032e64c64f1e63b2909c039c71 128 Pfam PF01592 NifU-like N terminal domain 2 126 5.2E-57 T 06-07-2017 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CAL12_RS17170 5fa31a032e64c64f1e63b2909c039c71 128 SUPERFAMILY SSF82649 1 125 3.92E-49 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 1.4E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 1.4E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 1.4E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 1.4E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 1.4E-52 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 SUPERFAMILY SSF52954 534 638 9.82E-31 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.10.20.30 1 69 7.4E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Pfam PF02824 TGS domain 2 66 2.1E-7 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 SMART SM00863 174 223 9.5E-26 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 638 33.933 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 223 1.5E-15 T 06-07-2017 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.30.980.10 71 134 8.3E-43 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.30.980.10 192 228 8.3E-43 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 533 7.3E-41 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 SUPERFAMILY SSF55681 247 530 1.24E-97 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.30.930.10 246 534 8.0E-120 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 SUPERFAMILY SSF81271 2 66 3.92E-10 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 635 3.3E-216 T 06-07-2017 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.30.54.20 136 191 1.6E-22 T 06-07-2017 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Gene3D G3DSA:3.40.50.800 535 639 8.7E-34 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 SUPERFAMILY SSF55186 68 245 5.76E-68 T 06-07-2017 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CAL12_RS09750 d807df859fc32bfee79da1a1549ffc69 649 Pfam PF03129 Anticodon binding domain 545 634 3.4E-19 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS07040 789acc22f131c5038cb19ebd8d057336 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 268 3.5E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07040 789acc22f131c5038cb19ebd8d057336 274 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 67 263 6.4E-72 T 06-07-2017 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 CAL12_RS07040 789acc22f131c5038cb19ebd8d057336 274 SUPERFAMILY SSF161098 78 262 3.66E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07040 789acc22f131c5038cb19ebd8d057336 274 Gene3D G3DSA:1.10.3720.10 75 270 9.7E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 Gene3D G3DSA:2.40.10.10 252 350 6.9E-32 T 06-07-2017 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 SUPERFAMILY SSF50494 183 349 6.99E-52 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 Gene3D G3DSA:2.40.10.10 173 251 8.8E-26 T 06-07-2017 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 Gene3D G3DSA:2.40.10.10 49 75 8.8E-26 T 06-07-2017 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 PRINTS PR00834 HtrA/DegQ protease family signature 216 236 5.9E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 PRINTS PR00834 HtrA/DegQ protease family signature 195 207 5.9E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 PRINTS PR00834 HtrA/DegQ protease family signature 296 313 5.9E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 PRINTS PR00834 HtrA/DegQ protease family signature 258 282 5.9E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 PRINTS PR00834 HtrA/DegQ protease family signature 318 335 5.9E-35 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS15395 a1d2a653b75fe2bfc3d01ed4739a86d7 359 Pfam PF13365 Trypsin-like peptidase domain 186 325 2.3E-34 T 06-07-2017 CAL12_RS08880 e2b61e300805209e910e82c66e560d18 355 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 251 268 - T 06-07-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CAL12_RS08880 e2b61e300805209e910e82c66e560d18 355 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 17 354 52.908 T 06-07-2017 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902 CAL12_RS08880 e2b61e300805209e910e82c66e560d18 355 Gene3D G3DSA:3.20.20.300 17 326 7.3E-92 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS08880 e2b61e300805209e910e82c66e560d18 355 SUPERFAMILY SSF51445 17 325 3.05E-82 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS08880 e2b61e300805209e910e82c66e560d18 355 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 19 306 6.8E-74 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 SUPERFAMILY SSF52738 153 338 5.1E-60 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 SMART SM00448 1 116 8.6E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 PIRSF PIRSF000876 1 340 2.4E-98 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 SUPERFAMILY SSF52172 2 105 4.7E-18 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 Pfam PF01339 CheB methylesterase 156 332 3.4E-53 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 337 32.037 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 Gene3D G3DSA:3.40.50.2300 2 104 1.1E-19 T 06-07-2017 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 Gene3D G3DSA:3.40.50.180 151 337 5.3E-66 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS19075 461a4f378d458827b9c6e4c9cb8cd5fb 341 Pfam PF00072 Response regulator receiver domain 4 102 9.0E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 Gene3D G3DSA:3.40.50.1400 234 354 1.3E-32 T 06-07-2017 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 Gene3D G3DSA:3.40.50.1400 34 233 1.4E-66 T 06-07-2017 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 ProSitePatterns PS00534 Ferrochelatase signature. 222 241 - T 06-07-2017 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 Pfam PF00762 Ferrochelatase 34 353 1.3E-109 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 SUPERFAMILY SSF53800 33 357 1.44E-104 T 06-07-2017 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 Hamap MF_00323 Ferrochelatase [hemH]. 33 353 37.366 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAL12_RS06225 ccbf8538b7911261c8c73289c53c7353 358 TIGRFAM TIGR00109 hemH: ferrochelatase 34 353 2.1E-90 T 06-07-2017 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CAL12_RS24395 8e76bf295502f8f67945d563c9176261 232 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 50 215 2.5E-22 T 06-07-2017 IPR005247 YbhB/YbcL CAL12_RS24395 8e76bf295502f8f67945d563c9176261 232 Pfam PF01161 Phosphatidylethanolamine-binding protein 49 215 2.5E-35 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS24395 8e76bf295502f8f67945d563c9176261 232 SUPERFAMILY SSF49777 19 217 1.96E-35 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS24395 8e76bf295502f8f67945d563c9176261 232 Gene3D G3DSA:3.90.280.10 19 221 7.9E-46 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS05220 56e4e2a89c1255507b01cac8882bbc5c 190 Gene3D G3DSA:1.20.1550.10 17 98 7.0E-10 T 06-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain CAL12_RS05220 56e4e2a89c1255507b01cac8882bbc5c 190 Pfam PF02600 Disulfide bond formation protein DsbB 15 99 1.7E-11 T 06-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CAL12_RS05220 56e4e2a89c1255507b01cac8882bbc5c 190 SUPERFAMILY SSF158442 17 129 1.83E-20 T 06-07-2017 CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 SUPERFAMILY SSF48452 114 223 2.8E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 Gene3D G3DSA:1.25.40.10 168 227 5.6E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 Pfam PF13432 Tetratricopeptide repeat 111 178 1.9E-13 T 06-07-2017 CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 107 224 1.0E-32 T 06-07-2017 IPR014162 Tol-Pal system, YbgF CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 Pfam PF13174 Tetratricopeptide repeat 182 214 2.0E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS22650 fd930745bab3054ebc6fb70fc6baa956 228 Gene3D G3DSA:1.25.40.10 118 167 5.6E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 Gene3D G3DSA:1.20.120.530 121 250 1.9E-17 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 SUPERFAMILY SSF46785 27 112 2.31E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 SUPERFAMILY SSF48008 120 248 2.09E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 SMART SM00895 121 243 6.5E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 91 3.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 Pfam PF07729 FCD domain 121 243 4.0E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 Gene3D G3DSA:1.10.10.10 20 91 2.5E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 5.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 5.3E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20805 5e43769806d9736400c6fd474843b261 264 SMART SM00345 35 96 2.8E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 SUPERFAMILY SSF46785 9 72 3.47E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 68 1.7E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 Gene3D G3DSA:3.40.640.10 118 343 4.7E-58 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 SUPERFAMILY SSF53383 63 446 2.29E-76 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 Gene3D G3DSA:1.10.10.10 9 75 3.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 SMART SM00345 9 68 1.6E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16560 ee2bea41920f36d11216185335522f43 450 Pfam PF00155 Aminotransferase class I and II 118 440 7.8E-30 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS10255 44f5a3e568ceb00057946ca6ed493149 163 Gene3D G3DSA:1.10.10.10 1 93 3.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10255 44f5a3e568ceb00057946ca6ed493149 163 SUPERFAMILY SSF46785 2 100 1.57E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10255 44f5a3e568ceb00057946ca6ed493149 163 Pfam PF03551 Transcriptional regulator PadR-like family 2 70 1.4E-15 T 06-07-2017 IPR005149 Transcription regulator PadR, N-terminal CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 Pfam PF00664 ABC transporter transmembrane region 34 307 3.3E-15 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 Gene3D G3DSA:1.20.1560.10 21 334 3.1E-36 T 06-07-2017 CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 SUPERFAMILY SSF52540 343 591 3.88E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 SUPERFAMILY SSF90123 21 335 2.62E-43 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 SMART SM00382 380 566 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 Gene3D G3DSA:3.40.50.300 354 584 9.6E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23420 c73e8f6e0c187e901044609ee028ff89 608 Pfam PF00005 ABC transporter 372 520 8.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25355 2932c5a1d7f7849a03d92c48f2414225 200 Gene3D G3DSA:3.40.50.150 17 181 4.3E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25355 2932c5a1d7f7849a03d92c48f2414225 200 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 10 197 7.1E-86 T 06-07-2017 IPR010743 Methionine biosynthesis MetW CAL12_RS25355 2932c5a1d7f7849a03d92c48f2414225 200 SUPERFAMILY SSF53335 10 190 2.5E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25355 2932c5a1d7f7849a03d92c48f2414225 200 Pfam PF07021 Methionine biosynthesis protein MetW 10 196 4.3E-75 T 06-07-2017 IPR010743 Methionine biosynthesis MetW CAL12_RS12985 a5de66b34c0c003447243d9febcc5d3b 329 Gene3D G3DSA:3.40.190.10 111 241 1.8E-16 T 06-07-2017 CAL12_RS12985 a5de66b34c0c003447243d9febcc5d3b 329 Gene3D G3DSA:3.40.190.10 48 83 6.5E-4 T 06-07-2017 CAL12_RS12985 a5de66b34c0c003447243d9febcc5d3b 329 SUPERFAMILY SSF53850 27 267 9.41E-38 T 06-07-2017 CAL12_RS12985 a5de66b34c0c003447243d9febcc5d3b 329 Pfam PF09084 NMT1/THI5 like 51 254 3.5E-19 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SUPERFAMILY SSF82282 20 411 1.12E-116 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Gene3D G3DSA:1.10.1240.10 670 761 2.6E-36 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 TIGRFAM TIGR02082 metH: methionine synthase 25 1227 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SUPERFAMILY SSF52242 773 928 4.45E-42 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Pfam PF00809 Pterin binding enzyme 372 610 7.3E-56 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SMART SM01018 677 764 7.6E-42 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SUPERFAMILY SSF51717 368 636 1.44E-86 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 PIRSF PIRSF000381 15 1230 0.0 T 06-07-2017 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SUPERFAMILY SSF56507 935 1257 1.31E-121 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 971 1242 1.1E-118 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Pfam PF02607 B12 binding domain 679 756 7.3E-26 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 SUPERFAMILY SSF47644 672 763 1.83E-26 T 06-07-2017 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Pfam PF02574 Homocysteine S-methyltransferase 29 337 1.2E-88 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Gene3D G3DSA:3.20.20.330 20 375 1.9E-124 T 06-07-2017 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Pfam PF02310 B12 binding domain 779 874 3.1E-18 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Gene3D G3DSA:3.20.20.20 376 637 6.0E-108 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Gene3D G3DSA:3.40.50.280 776 929 8.7E-63 T 06-07-2017 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CAL12_RS25535 c17814f51b68e82ea4f8ef7f3a6db50e 1258 Gene3D G3DSA:3.10.196.10 992 1257 8.3E-100 T 06-07-2017 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 SUPERFAMILY SSF50447 729 811 3.12E-25 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 560 715 4.8E-33 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Gene3D G3DSA:3.30.56.50 3 51 8.7E-15 T 06-07-2017 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Gene3D G3DSA:2.40.30.10 957 1053 1.1E-33 T 06-07-2017 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 ProSitePatterns PS01176 Initiation factor 2 signature. 1006 1028 - T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 478 529 1.2E-15 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 9.2E-8 T 06-07-2017 IPR006847 Translation initiation factor IF-2, N-terminal CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 98 3.7E-15 T 06-07-2017 IPR013575 Initiation factor 2 associated domain, bacterial CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 SUPERFAMILY SSF52540 550 726 1.7E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Gene3D G3DSA:3.40.50.10050 857 934 9.1E-25 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 472 1055 6.1E-256 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Gene3D G3DSA:3.40.50.300 557 715 2.8E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 SUPERFAMILY SSF50447 957 1053 5.61E-31 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Pfam PF00009 Elongation factor Tu GTP binding domain 561 716 4.0E-35 T 06-07-2017 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 SUPERFAMILY SSF52156 834 962 3.4E-37 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 SUPERFAMILY SSF46955 4 51 8.06E-9 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1053 17.391 T 06-07-2017 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Pfam PF11987 Translation-initiation factor 2 841 945 4.8E-37 T 06-07-2017 IPR023115 Translation initiation factor IF- 2, domain 3 CAL12_RS18430 3d40c2ed63d5603ac99ff6b4129fa5f6 1055 Gene3D G3DSA:2.40.30.10 728 821 4.1E-24 T 06-07-2017 CAL12_RS20875 d5bfedc0a26797dc60bd4e5e718e35c1 392 SUPERFAMILY SSF53850 180 352 5.44E-17 T 06-07-2017 CAL12_RS20875 d5bfedc0a26797dc60bd4e5e718e35c1 392 Gene3D G3DSA:3.40.190.10 196 309 6.9E-5 T 06-07-2017 CAL12_RS20875 d5bfedc0a26797dc60bd4e5e718e35c1 392 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 116 389 1.7E-91 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 Gene3D G3DSA:3.40.50.410 85 173 8.4E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 Gene3D G3DSA:3.40.50.410 229 320 2.4E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 SMART SM00327 82 322 4.0E-13 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 Pfam PF13519 von Willebrand factor type A domain 85 169 1.3E-14 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 Pfam PF00092 von Willebrand factor type A domain 230 318 4.9E-8 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 SUPERFAMILY SSF53300 84 176 1.01E-26 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS15380 9f796c4c88da3f6fcdfd4f5f22b9aba4 362 SUPERFAMILY SSF53300 226 321 1.01E-26 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 Gene3D G3DSA:3.90.180.10 1 144 2.3E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 Pfam PF00107 Zinc-binding dehydrogenase 149 264 1.3E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 SUPERFAMILY SSF51735 115 276 3.38E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 SMART SM00829 10 320 2.8E-44 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 2.6E-7 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 SUPERFAMILY SSF50129 1 142 4.11E-31 T 06-07-2017 IPR011032 GroES-like CAL12_RS16770 5d67264cfd587516023a4b229aa685cb 322 Gene3D G3DSA:3.40.50.720 145 260 1.6E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 Pfam PF00206 Lyase 20 299 8.5E-47 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 Gene3D G3DSA:1.20.200.10 104 370 3.8E-88 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 Gene3D G3DSA:1.10.275.10 5 103 1.2E-33 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 SMART SM00998 364 443 2.2E-28 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 Gene3D G3DSA:1.10.40.30 371 442 1.1E-30 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00149 Fumarate lyase superfamily signature 231 258 3.4E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 3.4E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00149 Fumarate lyase superfamily signature 146 164 3.4E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00149 Fumarate lyase superfamily signature 101 119 3.4E-24 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00145 Argininosuccinate lyase family signature 231 255 7.6E-11 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 7.6E-11 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00145 Argininosuccinate lyase family signature 100 122 7.6E-11 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 PRINTS PR00145 Argininosuccinate lyase family signature 141 161 7.6E-11 T 06-07-2017 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 SUPERFAMILY SSF48557 12 442 1.88E-120 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS24440 77ea8cfd7808de5ef5621c825a1f12eb 448 Pfam PF10397 Adenylosuccinate lyase C-terminus 365 441 6.1E-23 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Pfam PF00175 Oxidoreductase NAD-binding domain 439 549 5.3E-11 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Gene3D G3DSA:3.10.20.30 567 692 1.8E-20 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 169 264 4.4E-12 T 06-07-2017 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 PRINTS PR00410 Phenol hydroxylase reductase family signature 360 372 1.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 PRINTS PR00410 Phenol hydroxylase reductase family signature 537 545 1.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 PRINTS PR00410 Phenol hydroxylase reductase family signature 422 431 1.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 PRINTS PR00410 Phenol hydroxylase reductase family signature 438 457 1.4E-6 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 SUPERFAMILY SSF50475 167 282 4.58E-8 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Gene3D G3DSA:2.30.110.10 163 273 1.3E-7 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Gene3D G3DSA:2.40.30.10 327 428 2.9E-28 T 06-07-2017 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Gene3D G3DSA:3.40.50.80 432 566 7.8E-33 T 06-07-2017 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 SUPERFAMILY SSF63380 327 427 2.33E-25 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 SUPERFAMILY SSF52343 431 571 1.7E-34 T 06-07-2017 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 SUPERFAMILY SSF54292 605 692 9.7E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 630 690 5.5E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 651 659 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS14170 1bb5404a38cc20593ff5b7d3cc7c845b 701 Pfam PF00970 Oxidoreductase FAD-binding domain 333 427 2.7E-8 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS17985 da50c20d9b0a98c0536adf2d0cc21d0a 366 SUPERFAMILY SSF53756 8 358 7.49E-75 T 06-07-2017 CAL12_RS17985 da50c20d9b0a98c0536adf2d0cc21d0a 366 Pfam PF13439 Glycosyltransferase Family 4 15 161 8.6E-14 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS17985 da50c20d9b0a98c0536adf2d0cc21d0a 366 Gene3D G3DSA:3.40.50.2000 166 336 6.9E-29 T 06-07-2017 CAL12_RS17985 da50c20d9b0a98c0536adf2d0cc21d0a 366 Pfam PF00534 Glycosyl transferases group 1 170 336 1.7E-34 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 Gene3D G3DSA:3.40.190.10 225 255 1.8E-15 T 06-07-2017 CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 Gene3D G3DSA:3.40.190.10 32 125 1.8E-15 T 06-07-2017 CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 Gene3D G3DSA:3.40.190.10 126 224 6.2E-15 T 06-07-2017 CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 SUPERFAMILY SSF53850 26 260 1.55E-45 T 06-07-2017 CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 255 1.3E-30 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS05240 903edd1aa6d21579c09234b4ebec100b 340 SMART SM00062 35 265 1.2E-44 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS23640 8ab8d12b6a1280d3ee8b9ee882bc7a9b 42 Gene3D G3DSA:2.160.20.20 2 42 5.9E-6 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23640 8ab8d12b6a1280d3ee8b9ee882bc7a9b 42 SUPERFAMILY SSF51126 3 42 9.73E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23640 8ab8d12b6a1280d3ee8b9ee882bc7a9b 42 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 12 42 2.0E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23640 8ab8d12b6a1280d3ee8b9ee882bc7a9b 42 Pfam PF12951 Passenger-associated-transport-repeat 13 42 1.6E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS25630 64ce4c8c5fda431caa4685ea596de7c4 349 Gene3D G3DSA:2.40.100.10 213 322 1.4E-5 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS25630 64ce4c8c5fda431caa4685ea596de7c4 349 SUPERFAMILY SSF50891 210 315 1.74E-9 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS25630 64ce4c8c5fda431caa4685ea596de7c4 349 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 334 6.0E-82 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS25630 64ce4c8c5fda431caa4685ea596de7c4 349 Pfam PF02626 Allophanate hydrolase subunit 2 26 309 8.9E-82 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS25630 64ce4c8c5fda431caa4685ea596de7c4 349 SMART SM00797 24 326 1.3E-113 T 06-07-2017 IPR003778 Carboxyltransferase domain, subdomain A and B CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 SUPERFAMILY SSF103473 18 363 4.45E-43 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 PRINTS PR01035 Tetracycline resistance protein signature 116 138 5.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 PRINTS PR01035 Tetracycline resistance protein signature 318 341 5.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 PRINTS PR01035 Tetracycline resistance protein signature 28 47 5.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 PRINTS PR01035 Tetracycline resistance protein signature 230 250 5.2E-8 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 Gene3D G3DSA:1.20.1250.20 184 358 1.5E-13 T 06-07-2017 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 Gene3D G3DSA:1.20.1250.20 19 177 2.9E-24 T 06-07-2017 CAL12_RS05405 435b8e09395160604c0553db2f1259a0 375 Pfam PF07690 Major Facilitator Superfamily 18 327 1.1E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS05480 120c3199e6989bdb909b381e311a738e 382 SUPERFAMILY SSF53822 25 381 8.33E-73 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS05480 120c3199e6989bdb909b381e311a738e 382 Gene3D G3DSA:3.40.50.2300 25 217 5.1E-43 T 06-07-2017 CAL12_RS05480 120c3199e6989bdb909b381e311a738e 382 Pfam PF13458 Periplasmic binding protein 25 362 1.6E-53 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 SUPERFAMILY SSF51126 479 646 9.1E-30 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 SUPERFAMILY SSF51126 121 223 9.1E-30 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 SUPERFAMILY SSF51126 253 327 9.1E-30 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 SUPERFAMILY SSF103515 826 1093 1.44E-42 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 Gene3D G3DSA:2.160.20.20 123 310 9.9E-37 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 Gene3D G3DSA:2.160.20.20 475 646 9.9E-37 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 Pfam PF03797 Autotransporter beta-domain 832 1076 6.4E-40 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 Pfam PF03212 Pertactin 518 646 3.6E-19 T 06-07-2017 IPR004899 Pertactin, central region CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 962 979 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 1048 1073 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 830 850 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 870 894 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 1010 1031 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 1073 1093 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 PRINTS PR01484 Pertactin virulence factor family signature 981 1004 1.3E-29 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 SMART SM00869 830 1082 9.1E-34 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 541 1093 9.8E-80 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS23260 930cfbaf2a3959a7a6219b379513e6fe 1093 Gene3D G3DSA:2.40.128.130 780 1093 8.1E-58 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 256 1.1E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 SUPERFAMILY SSF53850 7 258 1.14E-57 T 06-07-2017 CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 Gene3D G3DSA:3.40.190.10 115 217 1.1E-18 T 06-07-2017 CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 SMART SM00062 35 258 4.4E-54 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 Gene3D G3DSA:3.40.190.10 32 114 1.5E-34 T 06-07-2017 CAL12_RS07485 fd0b2e1b60bfb4e64f4a243275b268ad 275 Gene3D G3DSA:3.40.190.10 218 258 1.5E-34 T 06-07-2017 CAL12_RS17765 a0ae864ebfa88ec730b26688e7484599 369 Gene3D G3DSA:3.30.465.10 56 177 6.2E-21 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS17765 a0ae864ebfa88ec730b26688e7484599 369 Gene3D G3DSA:1.10.45.10 345 365 2.7E-4 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS17765 a0ae864ebfa88ec730b26688e7484599 369 Pfam PF01565 FAD binding domain 10 139 1.9E-19 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS17765 a0ae864ebfa88ec730b26688e7484599 369 SUPERFAMILY SSF56176 7 177 2.52E-31 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS17765 a0ae864ebfa88ec730b26688e7484599 369 SUPERFAMILY SSF55103 195 367 8.18E-15 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS19660 fcb84693fd44f44458b008888afdd6c4 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 20.955 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAL12_RS19660 fcb84693fd44f44458b008888afdd6c4 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 2.3E-25 T 06-07-2017 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 SUPERFAMILY SSF52540 53 316 1.13E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 9.5E-29 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 SMART SM00382 53 245 9.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 1.2E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 Pfam PF00005 ABC transporter 46 195 1.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27920 f1926201e3fae0451ea2499b8969684f 353 Gene3D G3DSA:3.40.50.300 39 269 3.0E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15260 69b57c8f91d6423d1021a4582e2ecf00 329 SUPERFAMILY SSF53850 115 288 8.03E-12 T 06-07-2017 CAL12_RS15260 69b57c8f91d6423d1021a4582e2ecf00 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 323 1.6E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15260 69b57c8f91d6423d1021a4582e2ecf00 329 PIRSF PIRSF017082 4 327 2.7E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 1.3E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 Pfam PF03466 LysR substrate binding domain 92 297 2.9E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 Gene3D G3DSA:3.40.190.10 179 264 1.2E-18 T 06-07-2017 CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 SUPERFAMILY SSF46785 5 114 2.16E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 Gene3D G3DSA:1.10.10.10 6 88 6.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 SUPERFAMILY SSF53850 93 300 5.43E-43 T 06-07-2017 CAL12_RS20885 355d72e65f258b58a166f8ba9ed23c4e 318 Gene3D G3DSA:3.40.190.10 94 178 1.0E-22 T 06-07-2017 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF55785 124 249 5.48E-26 T 06-07-2017 IPR000014 PAS domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:3.40.50.2300 559 680 1.6E-29 T 06-07-2017 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:3.40.50.2300 708 825 6.3E-28 T 06-07-2017 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF52172 562 683 1.2E-22 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 421 537 7.5E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00388 305 377 2.3E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF52172 708 825 1.35E-26 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00448 710 822 1.6E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00448 1 112 2.1E-6 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00448 561 674 1.6E-16 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:3.40.50.2300 2 132 1.8E-17 T 06-07-2017 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF00512 His Kinase A (phospho-acceptor) domain 307 375 2.9E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:3.30.565.10 377 537 2.3E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF00072 Response regulator receiver domain 563 674 5.5E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF00072 Response regulator receiver domain 712 822 5.4E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF00072 Response regulator receiver domain 2 104 1.3E-11 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00091 137 203 5.5E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 133 258 2.2E-14 T 06-07-2017 IPR000014 PAS domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF55874 368 537 7.2E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:1.10.287.130 298 373 6.5E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF47384 294 374 6.28E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SMART SM00387 418 539 2.2E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Pfam PF08448 PAS fold 144 252 3.2E-12 T 06-07-2017 IPR013656 PAS fold-4 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 Gene3D G3DSA:3.30.450.20 133 249 1.0E-28 T 06-07-2017 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 482 2.8E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 523 536 2.8E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 517 2.8E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 496 2.8E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13055 68d6d2080e525f2114980ed64843536a 830 SUPERFAMILY SSF52172 2 155 5.98E-21 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 SUPERFAMILY SSF53686 4 354 2.23E-91 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 305 1.3E-74 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 399 1.4E-130 T 06-07-2017 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 Gene3D G3DSA:3.30.70.260 325 396 5.8E-9 T 06-07-2017 CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 Pfam PF01842 ACT domain 329 393 2.8E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS20900 d0faacb22e8ec3a7de6f773faeb47fc1 405 Gene3D G3DSA:3.40.50.1100 69 323 3.2E-72 T 06-07-2017 CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 258 1.3E-52 T 06-07-2017 CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 Gene3D G3DSA:3.40.50.720 20 259 8.1E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 3.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 3.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 3.3E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 SUPERFAMILY SSF51735 21 258 6.99E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 22 258 4.5E-109 T 06-07-2017 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS10135 e1bbe3735c44f759da0a97423b3dc9a3 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 20 211 3.3E-4 T 06-07-2017 CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 Gene3D G3DSA:3.40.50.720 3 229 3.2E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 SUPERFAMILY SSF51735 4 229 9.61E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16090 25ab565f8940227dbd314f2581d4266d 229 Pfam PF00106 short chain dehydrogenase 5 191 1.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 Pfam PF01545 Cation efflux family 10 213 6.2E-35 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 Gene3D G3DSA:3.30.70.1350 219 297 1.9E-11 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 Gene3D G3DSA:1.20.1510.10 6 216 1.2E-37 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 299 3.0E-50 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 SUPERFAMILY SSF160240 220 298 7.59E-12 T 06-07-2017 CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 Pfam PF16916 Dimerisation domain of Zinc Transporter 223 296 1.8E-9 T 06-07-2017 IPR027470 Cation efflux protein, cytoplasmic domain CAL12_RS20010 a2696f9b30d034c9b56f8dd67cbcfe92 311 SUPERFAMILY SSF161111 5 218 9.29E-43 T 06-07-2017 CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 Gene3D G3DSA:3.40.1160.10 30 297 5.9E-103 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 PIRSF PIRSF000728 17 298 7.5E-102 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 TIGRFAM TIGR00761 argB: acetylglutamate kinase 33 273 1.0E-73 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 SUPERFAMILY SSF53633 15 298 1.7E-88 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 Pfam PF00696 Amino acid kinase family 32 275 8.9E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS26160 8c71f394f3cfa4104eb1c8abdda931bb 299 Hamap MF_00082_B Acetylglutamate kinase [argB]. 30 298 35.624 T 06-07-2017 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Pfam PF01266 FAD dependent oxidoreductase 9 382 1.0E-57 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.50.50.60 223 251 4.1E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.50.50.60 141 190 4.1E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.50.50.60 343 400 4.1E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.50.50.60 6 83 4.1E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 SUPERFAMILY SSF51905 222 252 3.88E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 SUPERFAMILY SSF51905 343 401 3.88E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 SUPERFAMILY SSF51905 8 190 3.88E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.30.9.10 87 140 4.3E-14 T 06-07-2017 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 Gene3D G3DSA:3.30.9.10 252 339 4.3E-14 T 06-07-2017 CAL12_RS27135 4205bc87ac070ca584135f32cdcd733d 422 SUPERFAMILY SSF54373 270 338 1.11E-5 T 06-07-2017 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 SMART SM00344 12 118 2.0E-36 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 Gene3D G3DSA:1.10.10.10 11 63 8.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 SUPERFAMILY SSF54909 74 145 2.82E-14 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 SUPERFAMILY SSF46785 12 72 9.82E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 Gene3D G3DSA:3.30.70.920 65 137 1.3E-17 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 1.6E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 1.6E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 1.6E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 Pfam PF13404 AsnC-type helix-turn-helix domain 12 53 2.6E-15 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15605 796d4ec818d7dc2cc2242f8dd64b15d0 155 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 1.1E-13 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS27695 d363b43793977e14458243151b27dadb 239 Gene3D G3DSA:1.10.3720.10 22 226 1.7E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27695 d363b43793977e14458243151b27dadb 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 121 4.1E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS27695 d363b43793977e14458243151b27dadb 239 SUPERFAMILY SSF161098 22 212 3.79E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27695 d363b43793977e14458243151b27dadb 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 227 2.9E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15820 bf3693aa6641f731f584fd16361741d2 489 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 18 420 2.2E-105 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS15820 bf3693aa6641f731f584fd16361741d2 489 SUPERFAMILY SSF50475 15 304 2.98E-85 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS15820 bf3693aa6641f731f584fd16361741d2 489 SUPERFAMILY SSF143968 306 457 3.66E-39 T 06-07-2017 CAL12_RS15820 bf3693aa6641f731f584fd16361741d2 489 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 23 410 1.0E-112 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS15820 bf3693aa6641f731f584fd16361741d2 489 Gene3D G3DSA:3.40.1670.10 321 448 1.0E-34 T 06-07-2017 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 Pfam PF03466 LysR substrate binding domain 136 340 1.3E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 Gene3D G3DSA:3.40.190.10 140 225 6.7E-25 T 06-07-2017 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 Gene3D G3DSA:3.40.190.10 226 308 1.5E-9 T 06-07-2017 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 67 78 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 88 99 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 78 88 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 SUPERFAMILY SSF46785 39 159 2.99E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 52 110 4.6E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 Gene3D G3DSA:1.10.10.10 50 131 8.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11605 577ab5fe20fbb0752d251798eaf389d0 361 SUPERFAMILY SSF53850 138 345 1.86E-46 T 06-07-2017 CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 SMART SM00346 4 91 1.4E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 Pfam PF09339 IclR helix-turn-helix domain 6 55 5.7E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 SUPERFAMILY SSF55781 67 210 8.5E-9 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 SUPERFAMILY SSF46785 6 74 3.03E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 Gene3D G3DSA:3.30.450.40 70 162 1.5E-8 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS15100 44f3d9eb0c6680433afef9389ad1db7e 215 Gene3D G3DSA:1.10.10.10 5 69 2.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13380 2385b821b01a4ad7716270cd21a2bffd 310 SUPERFAMILY SSF53850 84 272 2.72E-14 T 06-07-2017 CAL12_RS13380 2385b821b01a4ad7716270cd21a2bffd 310 Gene3D G3DSA:3.40.190.10 115 232 1.4E-6 T 06-07-2017 CAL12_RS13380 2385b821b01a4ad7716270cd21a2bffd 310 PIRSF PIRSF017082 1 310 5.4E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13380 2385b821b01a4ad7716270cd21a2bffd 310 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 36 306 2.3E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 68 77 - T 06-07-2017 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 SMART SM00986 60 225 1.1E-31 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 19 229 2.9E-69 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 Pfam PF03167 Uracil DNA glycosylase superfamily 64 224 4.9E-24 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 SUPERFAMILY SSF52141 15 237 3.49E-75 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 17 236 34.602 T 06-07-2017 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 Gene3D G3DSA:3.40.470.10 7 237 5.6E-81 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS26555 1f98c63cd7896f6e9147fd06e8314182 250 SMART SM00987 60 225 1.1E-31 T 06-07-2017 CAL12_RS21450 5332bb1753a1e0d99faef45a7248729a 423 Pfam PF13437 HlyD family secretion protein 287 386 3.7E-11 T 06-07-2017 CAL12_RS21450 5332bb1753a1e0d99faef45a7248729a 423 Gene3D G3DSA:2.40.50.100 284 294 3.6E-8 T 06-07-2017 CAL12_RS21450 5332bb1753a1e0d99faef45a7248729a 423 Gene3D G3DSA:2.40.50.100 192 223 3.6E-8 T 06-07-2017 CAL12_RS21450 5332bb1753a1e0d99faef45a7248729a 423 SUPERFAMILY SSF111369 181 364 3.53E-15 T 06-07-2017 CAL12_RS21450 5332bb1753a1e0d99faef45a7248729a 423 Pfam PF13533 Biotin-lipoyl like 193 237 1.0E-8 T 06-07-2017 CAL12_RS00405 842a336280aee559f143d267c700e497 301 SUPERFAMILY SSF51197 5 231 1.65E-49 T 06-07-2017 CAL12_RS00405 842a336280aee559f143d267c700e497 301 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 15 223 8.2E-31 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAL12_RS00405 842a336280aee559f143d267c700e497 301 Gene3D G3DSA:2.60.120.620 3 231 1.8E-52 T 06-07-2017 CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Gene3D G3DSA:3.40.50.970 382 581 1.8E-24 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 SUPERFAMILY SSF52518 8 201 2.36E-33 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Gene3D G3DSA:3.40.50.970 13 190 2.0E-34 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 570 2.0E-18 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 212 293 1.2E-9 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 187 3.5E-33 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 SUPERFAMILY SSF52518 412 579 8.11E-27 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 Gene3D G3DSA:3.40.50.1220 202 294 1.1E-14 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS21745 e4126d4ceadbf21cd74b2b855bfa75f8 588 SUPERFAMILY SSF52467 199 325 4.44E-14 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 Gene3D G3DSA:3.90.79.10 51 186 9.7E-33 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 SUPERFAMILY SSF55811 17 178 1.14E-40 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 Pfam PF14803 Nudix N-terminal 17 50 2.9E-18 T 06-07-2017 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 Gene3D G3DSA:2.20.70.10 16 50 8.7E-19 T 06-07-2017 CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 Pfam PF00293 NUDIX domain 53 156 2.4E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS05780 eefa7dd775209ac1eb71d782d6eca700 192 ProSitePatterns PS00893 Nudix box signature. 85 106 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 394 39.904 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 SUPERFAMILY SSF53748 15 394 2.83E-142 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PIRSF PIRSF000724 1 397 6.6E-137 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 20 30 - T 06-07-2017 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 Gene3D G3DSA:3.40.50.1270 181 382 8.4E-82 T 06-07-2017 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 314 339 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 169 191 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 192 211 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 37 59 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 370 387 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 347 358 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 138 160 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 PRINTS PR00477 Phosphoglycerate kinase family signature 15 31 4.8E-83 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 Gene3D G3DSA:3.40.50.1260 15 180 3.5E-62 T 06-07-2017 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS05020 2ed719d1b029b138e154430e25da50a6 397 Pfam PF00162 Phosphoglycerate kinase 15 384 2.1E-137 T 06-07-2017 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 Gene3D G3DSA:1.10.287.950 286 491 1.1E-56 T 06-07-2017 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 SUPERFAMILY SSF58104 240 525 2.22E-66 T 06-07-2017 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 447 476 6.8E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 293 322 6.8E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 370 397 6.8E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 399 428 6.8E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 16 41 6.8E-55 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 177 2.2E-16 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 518 8.8E-54 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS22020 8b971bba88253cbbd8f125cd4490c440 560 SMART SM00283 272 519 3.7E-81 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 TIGRFAM TIGR00400 mgtE: magnesium transporter 56 489 6.9E-84 T 06-07-2017 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SMART SM00116 249 297 0.081 T 06-07-2017 IPR000644 CBS domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SMART SM00116 185 238 2.6 T 06-07-2017 IPR000644 CBS domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Pfam PF01769 Divalent cation transporter 361 483 7.6E-22 T 06-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SMART SM00924 75 178 9.7E-37 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SUPERFAMILY SSF54631 177 312 8.72E-28 T 06-07-2017 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SUPERFAMILY SSF158791 53 175 3.01E-26 T 06-07-2017 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Pfam PF00571 CBS domain 178 234 7.4E-5 T 06-07-2017 IPR000644 CBS domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Pfam PF00571 CBS domain 242 296 3.1E-7 T 06-07-2017 IPR000644 CBS domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Gene3D G3DSA:3.10.580.10 173 302 1.5E-16 T 06-07-2017 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 SUPERFAMILY SSF161093 319 489 1.96E-43 T 06-07-2017 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Gene3D G3DSA:1.25.60.10 51 172 7.8E-25 T 06-07-2017 CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Pfam PF03448 MgtE intracellular N domain 75 176 3.0E-25 T 06-07-2017 IPR006668 Magnesium transporter, MgtE intracellular domain CAL12_RS22240 d3f3b3772783433a5e0d2621232a058c 490 Gene3D G3DSA:1.10.357.20 318 489 7.2E-48 T 06-07-2017 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 Gene3D G3DSA:1.20.1270.130 1311 1377 7.0E-6 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 Gene3D G3DSA:1.20.58.360 1395 1528 1.5E-32 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 Pfam PF14496 C-terminal novel E3 ligase, LRR-interacting 1319 1532 1.4E-37 T 06-07-2017 IPR029487 Novel E3 ligase domain GO:0004842|GO:0016567 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1161 1180 0.0012 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1181 1200 0.39 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1119 1138 31.0 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1140 1159 1.2 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1222 1241 31.0 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1078 1097 3.7 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1099 1118 11.0 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1243 1262 75.0 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SMART SM00364 1201 1220 11.0 T 06-07-2017 CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 Gene3D G3DSA:3.80.10.10 1129 1277 5.7E-30 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 Gene3D G3DSA:3.80.10.10 1022 1128 2.2E-18 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS19200 fce43c58508d046d03217aea2fff24e5 1602 SUPERFAMILY SSF52058 1022 1277 2.52E-30 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 14 266 2.2E-57 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 13 95 6.3E-13 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 177 240 6.7E-13 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 Gene3D G3DSA:3.30.1240.10 92 185 3.0E-7 T 06-07-2017 CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 13 266 1.3E-53 T 06-07-2017 IPR000150 Cof protein GO:0016787 CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 06-07-2017 CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 Gene3D G3DSA:3.40.50.1000 186 272 2.8E-43 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 Gene3D G3DSA:3.40.50.1000 10 81 2.8E-43 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS22855 dd4a8122c01e89b095aa22b951dafc23 275 SUPERFAMILY SSF56784 11 272 8.39E-61 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 Gene3D G3DSA:3.40.190.10 88 226 2.3E-27 T 06-07-2017 CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.4E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 Pfam PF03466 LysR substrate binding domain 87 291 6.8E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 SUPERFAMILY SSF46785 1 86 3.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 Gene3D G3DSA:1.10.10.10 1 84 2.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15865 f4bc98f6f59d378851429df4d9f48a77 300 SUPERFAMILY SSF53850 88 295 1.06E-37 T 06-07-2017 CAL12_RS06775 effff496358e03ed4f048132c9cf1d0f 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 336 1.2E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06775 effff496358e03ed4f048132c9cf1d0f 340 SUPERFAMILY SSF53850 132 302 4.13E-10 T 06-07-2017 CAL12_RS06775 effff496358e03ed4f048132c9cf1d0f 340 PIRSF PIRSF017082 12 340 1.0E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 SUPERFAMILY SSF54665 26 175 8.37E-41 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 SMART SM01008 42 159 8.5E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.90.1170.50 24 147 6.0E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 203 309 3.6E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 189 731 9.1E-160 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 42 159 1.5E-27 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 148 202 1.3E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 312 386 1.3E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 389 486 6.4E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 646 793 6.4E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 Gene3D G3DSA:3.30.365.10 487 643 5.6E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03275 69d094dfc39eb3643a5c1f8c55364f73 809 SUPERFAMILY SSF56003 151 794 1.15E-178 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1366 0.0 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF00562 RNA polymerase Rpb2, domain 6 725 1292 1.0E-158 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 06-07-2017 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 226 9.2E-6 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 355 460 8.6E-16 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 2.2E-25 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.40.50.150 834 943 9.9E-56 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.40.50.150 1064 1078 9.9E-56 T 06-07-2017 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.30.150.10 598 662 6.5E-29 T 06-07-2017 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.233 T 06-07-2017 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:3.90.1110.10 157 234 3.7E-64 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:3.90.1110.10 351 450 3.7E-64 T 06-07-2017 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.40.270.10 799 826 2.9E-86 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.40.270.10 1079 1270 2.9E-86 T 06-07-2017 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:3.90.1100.10 21 155 7.0E-147 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:3.90.1100.10 665 719 7.0E-147 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:3.90.1100.10 451 597 7.0E-147 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 1.0E-25 T 06-07-2017 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF04563 RNA polymerase beta subunit 27 506 1.5E-36 T 06-07-2017 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Gene3D G3DSA:2.40.50.100 721 798 8.5E-29 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 SUPERFAMILY SSF64484 348 945 0.0 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 SUPERFAMILY SSF64484 1058 1368 0.0 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 SUPERFAMILY SSF64484 12 230 0.0 T 06-07-2017 CAL12_RS27750 9f630702b3aa37767057f6f6ef5b98e5 1370 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.6E-31 T 06-07-2017 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS10120 885ca1a2444143cb51f8252df1839a39 153 Gene3D G3DSA:1.10.10.410 94 153 1.6E-16 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAL12_RS10120 885ca1a2444143cb51f8252df1839a39 153 SUPERFAMILY SSF89095 5 152 7.32E-37 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAL12_RS10120 885ca1a2444143cb51f8252df1839a39 153 Gene3D G3DSA:1.10.1510.10 5 93 8.1E-32 T 06-07-2017 CAL12_RS10120 885ca1a2444143cb51f8252df1839a39 153 Pfam PF09424 Yqey-like protein 7 152 6.8E-49 T 06-07-2017 IPR019004 Uncharacterised domain YOR215C, mitochondrial CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 06-07-2017 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 4.3E-44 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 Gene3D G3DSA:3.90.470.10 1 107 1.1E-39 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 SUPERFAMILY SSF54843 1 107 5.76E-39 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 24.366 T 06-07-2017 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27630 4a372c6365de47b892a6c4ae6dde9891 109 Pfam PF00237 Ribosomal protein L22p/L17e 9 107 1.9E-31 T 06-07-2017 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 SUPERFAMILY SSF46689 287 338 3.14E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 54 67 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 116 131 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 Gene3D G3DSA:1.10.8.60 220 260 3.6E-6 T 06-07-2017 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 302 319 1.6E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 319 339 1.6E-5 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 Pfam PF02954 Bacterial regulatory protein, Fis family 300 336 3.9E-9 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 Pfam PF00158 Sigma-54 interaction domain 31 196 2.8E-63 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 SMART SM00382 50 193 1.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 241 250 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 Gene3D G3DSA:3.40.50.300 29 201 5.4E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 Gene3D G3DSA:1.10.10.60 299 335 5.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS08130 0f562ca5fb315a28c76394b13e80cb99 351 SUPERFAMILY SSF52540 30 260 1.21E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 SUPERFAMILY SSF64005 13 238 2.88E-84 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 Gene3D G3DSA:3.40.1180.10 11 249 2.0E-96 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 8.6E-87 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 1.1E-77 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 06-07-2017 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CAL12_RS12135 0e105dd5603025bfe9d99f2c3bad773c 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 39.222 T 06-07-2017 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CAL12_RS12680 60fc9b7de727240fec1cf2394a59b05f 327 SUPERFAMILY SSF53850 117 289 1.04E-8 T 06-07-2017 CAL12_RS12680 60fc9b7de727240fec1cf2394a59b05f 327 Gene3D G3DSA:3.40.190.10 131 235 1.9E-4 T 06-07-2017 CAL12_RS12680 60fc9b7de727240fec1cf2394a59b05f 327 PIRSF PIRSF017082 1 326 2.4E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12680 60fc9b7de727240fec1cf2394a59b05f 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 1.1E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 SMART SM00895 90 214 3.8E-14 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 Gene3D G3DSA:1.20.120.530 84 227 1.2E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 Pfam PF07729 FCD domain 94 212 1.2E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 Gene3D G3DSA:1.10.10.10 7 81 3.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 SMART SM00345 22 80 1.1E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 SUPERFAMILY SSF48008 89 221 4.97E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 SUPERFAMILY SSF46785 13 84 9.79E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15170 7d0c8c6ccf59aa4168c7df438b71de12 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 80 2.8E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 40 133 8.89E-27 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:3.30.70.1430 576 680 6.1E-22 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 3.1E-86 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 681 730 2.09E-25 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 817 866 2.09E-25 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82714 731 815 5.36E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:3.30.70.1430 40 141 3.7E-33 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82866 299 499 7.72E-51 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:1.20.1640.10 295 509 2.7E-61 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82714 185 274 7.06E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82866 846 1037 4.45E-44 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Pfam PF00873 AcrB/AcrD/AcrF family 3 1037 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 574 680 2.09E-22 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:3.30.2090.10 731 817 8.3E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:3.30.2090.10 184 278 1.4E-23 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 Gene3D G3DSA:1.10.3850.10 824 1038 1.7E-58 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 138 184 2.79E-24 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 SUPERFAMILY SSF82693 277 333 2.79E-24 T 06-07-2017 CAL12_RS14395 901c7bf575d21f149fe9fe3cd69e548e 1061 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1053 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS15580 79a4318bffb4d54edc4800d04fc72bf3 117 Gene3D G3DSA:3.40.30.10 1 116 2.6E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15580 79a4318bffb4d54edc4800d04fc72bf3 117 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 115 8.1E-42 T 06-07-2017 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 CAL12_RS15580 79a4318bffb4d54edc4800d04fc72bf3 117 Pfam PF03960 ArsC family 6 114 1.6E-14 T 06-07-2017 IPR006660 Arsenate reductase-like CAL12_RS15580 79a4318bffb4d54edc4800d04fc72bf3 117 SUPERFAMILY SSF52833 3 116 2.04E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS07980 b3c67e987861abc486b3dd972612e2c5 301 SUPERFAMILY SSF53448 32 232 2.97E-49 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07980 b3c67e987861abc486b3dd972612e2c5 301 Gene3D G3DSA:3.90.550.10 32 238 7.4E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07980 b3c67e987861abc486b3dd972612e2c5 301 Pfam PF00535 Glycosyl transferase family 2 35 190 2.3E-25 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS04025 a7f47412b94ac2481cbbbb643b11d8f6 163 Gene3D G3DSA:2.40.33.20 7 161 8.7E-19 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like CAL12_RS04025 a7f47412b94ac2481cbbbb643b11d8f6 163 SUPERFAMILY SSF50800 6 161 1.26E-21 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAL12_RS22350 06c4e8d6e1bd4e9f20bed34019bd3e88 340 PIRSF PIRSF017082 8 338 1.7E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22350 06c4e8d6e1bd4e9f20bed34019bd3e88 340 SUPERFAMILY SSF53850 136 300 3.8E-10 T 06-07-2017 CAL12_RS22350 06c4e8d6e1bd4e9f20bed34019bd3e88 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 334 6.4E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03470 5ed92176905496b5619d35ba372c3a0d 473 Gene3D G3DSA:1.20.1250.20 38 223 5.3E-23 T 06-07-2017 CAL12_RS03470 5ed92176905496b5619d35ba372c3a0d 473 SUPERFAMILY SSF103473 21 226 7.06E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03470 5ed92176905496b5619d35ba372c3a0d 473 SUPERFAMILY SSF103473 271 465 7.06E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03470 5ed92176905496b5619d35ba372c3a0d 473 Gene3D G3DSA:1.20.1250.20 288 462 1.8E-16 T 06-07-2017 CAL12_RS03470 5ed92176905496b5619d35ba372c3a0d 473 Pfam PF07690 Major Facilitator Superfamily 48 433 4.2E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 257 3.5E-63 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 Gene3D G3DSA:3.40.190.10 116 215 4.1E-28 T 06-07-2017 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 Gene3D G3DSA:3.40.190.10 218 260 8.2E-43 T 06-07-2017 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 Gene3D G3DSA:3.40.190.10 36 115 8.2E-43 T 06-07-2017 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 SUPERFAMILY SSF53850 5 259 5.98E-68 T 06-07-2017 CAL12_RS21815 258eb886ab76848119577a01d1bdf8dc 263 SMART SM00062 39 259 5.2E-70 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 SUPERFAMILY SSF50615 3 80 1.39E-23 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.435 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Gene3D G3DSA:3.40.50.300 81 348 3.3E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 347 3.5E-64 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 1.3E-17 T 06-07-2017 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 465 1.7E-249 T 06-07-2017 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Gene3D G3DSA:1.10.1140.10 350 466 2.1E-56 T 06-07-2017 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 SUPERFAMILY SSF47917 350 465 5.49E-54 T 06-07-2017 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 Gene3D G3DSA:2.40.10.170 2 80 6.1E-28 T 06-07-2017 CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 SUPERFAMILY SSF52540 82 352 3.26E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25795 2be4ff626a000816a7bb43eb05bf0849 466 SMART SM00382 147 410 0.0021 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 SUPERFAMILY SSF53850 89 289 1.46E-35 T 06-07-2017 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 Pfam PF03466 LysR substrate binding domain 88 288 9.9E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.2E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 SUPERFAMILY SSF46785 3 84 8.33E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 Gene3D G3DSA:3.40.190.10 177 265 1.5E-26 T 06-07-2017 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 Gene3D G3DSA:3.40.190.10 89 176 1.1E-23 T 06-07-2017 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.9E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23165 6b669ba41b67e968763dfe8c4ec0ebd7 292 Gene3D G3DSA:1.10.10.10 3 85 4.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 SUPERFAMILY SSF47741 93 163 3.27E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 Gene3D G3DSA:3.10.20.30 10 83 3.9E-30 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 Pfam PF01799 [2Fe-2S] binding domain 82 153 2.4E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 68 1.2E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 SUPERFAMILY SSF54292 11 87 1.22E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS00190 a63b2edec51d58dfd30dff6782273181 168 Gene3D G3DSA:1.10.150.120 84 164 2.7E-35 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS08430 839a5fb1ffd1b60c70db1049fe2509b9 437 Pfam PF07690 Major Facilitator Superfamily 20 349 2.4E-11 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS08430 839a5fb1ffd1b60c70db1049fe2509b9 437 SUPERFAMILY SSF103473 16 435 2.09E-28 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS08430 839a5fb1ffd1b60c70db1049fe2509b9 437 Gene3D G3DSA:1.20.1250.20 17 195 4.6E-14 T 06-07-2017 CAL12_RS27030 39bffc0fccd17dfb7fe34f534bf263f2 189 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 140 4.8E-31 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS27030 39bffc0fccd17dfb7fe34f534bf263f2 189 Gene3D G3DSA:3.30.530.20 1 157 9.4E-46 T 06-07-2017 IPR023393 START-like domain CAL12_RS27030 39bffc0fccd17dfb7fe34f534bf263f2 189 SUPERFAMILY SSF55961 1 145 5.5E-33 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Gene3D G3DSA:3.40.190.10 94 180 3.0E-33 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Gene3D G3DSA:3.30.70.260 275 360 8.5E-29 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Gene3D G3DSA:3.40.190.10 181 258 2.0E-24 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 308 315 - T 06-07-2017 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Pfam PF01817 Chorismate mutase type II 13 91 2.7E-22 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 SUPERFAMILY SSF48600 8 97 2.2E-19 T 06-07-2017 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Pfam PF00800 Prephenate dehydratase 97 270 4.1E-61 T 06-07-2017 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Pfam PF01842 ACT domain 282 345 1.8E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 Gene3D G3DSA:1.20.59.10 6 91 2.5E-20 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 TIGRFAM TIGR01807 CM_P2: chorismate mutase 9 84 2.7E-27 T 06-07-2017 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 SUPERFAMILY SSF55021 265 360 9.99E-25 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 PIRSF PIRSF001500 2 361 6.7E-137 T 06-07-2017 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 SUPERFAMILY SSF53850 95 278 3.8E-57 T 06-07-2017 CAL12_RS18945 fc846cb0c1b8a0e9f8b5b9c93ca22907 361 SMART SM00830 13 94 3.2E-27 T 06-07-2017 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 3.8E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 Gene3D G3DSA:3.40.190.10 92 177 5.5E-18 T 06-07-2017 CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 Pfam PF03466 LysR substrate binding domain 89 295 7.2E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 Gene3D G3DSA:1.10.10.10 3 85 2.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 Gene3D G3DSA:3.40.190.10 178 263 1.3E-20 T 06-07-2017 CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 SUPERFAMILY SSF46785 5 85 2.33E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04595 da2acd94abb68582782770781c5b4863 314 SUPERFAMILY SSF53850 90 298 1.52E-40 T 06-07-2017 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Gene3D G3DSA:1.10.3120.10 213 393 3.6E-55 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 239 7.1E-15 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Gene3D G3DSA:3.30.70.1050 1 118 1.1E-32 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Hamap MF_00303 Trigger factor [tig]. 1 423 20.357 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 417 1.9E-33 T 06-07-2017 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 5.8E-37 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 Gene3D G3DSA:3.10.50.40 153 212 1.6E-9 T 06-07-2017 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 PIRSF PIRSF003095 1 436 8.5E-127 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 SUPERFAMILY SSF54534 103 243 1.91E-31 T 06-07-2017 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 SUPERFAMILY SSF109998 250 435 3.53E-44 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 SUPERFAMILY SSF102735 1 130 3.01E-32 T 06-07-2017 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CAL12_RS17220 167de14073c8cf52b4c10a00e2866314 436 TIGRFAM TIGR00115 tig: trigger factor 11 417 4.1E-132 T 06-07-2017 IPR005215 Trigger factor GO:0015031 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Pfam PF00384 Molybdopterin oxidoreductase 111 414 5.2E-24 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 PIRSF PIRSF000144 1 763 0.0 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 15 761 1.7E-291 T 06-07-2017 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Gene3D G3DSA:3.40.50.740 396 629 3.8E-51 T 06-07-2017 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Gene3D G3DSA:3.40.50.740 111 183 3.8E-51 T 06-07-2017 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Pfam PF01568 Molydopterin dinucleotide binding domain 649 754 2.2E-6 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 SUPERFAMILY SSF53706 49 630 1.7E-135 T 06-07-2017 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Gene3D G3DSA:3.40.228.10 184 395 5.0E-57 T 06-07-2017 CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 SUPERFAMILY SSF50692 646 762 4.07E-13 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS07170 52f31737fa01d71a693bb0eef0d6fbb6 763 Gene3D G3DSA:2.40.40.20 648 721 5.4E-6 T 06-07-2017 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 Gene3D G3DSA:1.10.287.130 230 300 1.6E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 Gene3D G3DSA:3.30.565.10 306 436 5.0E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 SUPERFAMILY SSF47384 223 304 9.42E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 435 3.0E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 SMART SM00387 347 457 1.9E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 241 303 6.9E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 SUPERFAMILY SSF55874 294 438 5.5E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 SMART SM00388 239 304 7.8E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 412 2.9E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 398 2.9E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26285 9b76e08a9dc5ee45a989e00b62d2da01 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 2.9E-8 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 Gene3D G3DSA:3.40.50.300 12 252 2.6E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 SUPERFAMILY SSF52540 13 254 1.13E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 SMART SM00382 39 232 9.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 254 2.6E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS03345 264b24fc51ad9f58f4ec25383024f5d7 259 Pfam PF00005 ABC transporter 31 185 4.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 Gene3D G3DSA:3.40.190.10 91 177 2.6E-18 T 06-07-2017 CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 Pfam PF03466 LysR substrate binding domain 90 292 2.1E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 SUPERFAMILY SSF46785 2 112 3.21E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 SUPERFAMILY SSF53850 90 296 4.1E-37 T 06-07-2017 CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 Gene3D G3DSA:3.40.190.10 178 264 5.3E-15 T 06-07-2017 CAL12_RS02520 181d3bc7eb5fee801b92b59e6bd959d8 306 Gene3D G3DSA:1.10.10.10 3 89 1.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Pfam PF02254 TrkA-N domain 3 123 2.2E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Pfam PF02254 TrkA-N domain 234 351 4.8E-25 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Gene3D G3DSA:3.30.70.1450 391 438 2.3E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Gene3D G3DSA:3.40.50.720 1 151 4.0E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Gene3D G3DSA:3.40.50.720 232 377 3.8E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 SUPERFAMILY SSF116726 380 441 1.96E-9 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.8E-22 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.8E-22 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.8E-22 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.8E-22 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.8E-22 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 SUPERFAMILY SSF51735 232 377 1.46E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Gene3D G3DSA:3.30.70.1450 152 224 1.3E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 SUPERFAMILY SSF116726 136 222 4.58E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 SUPERFAMILY SSF51735 1 151 1.09E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Pfam PF02080 TrkA-C domain 391 452 9.8E-11 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS26250 22fb958fad6d7cf6d2a7c9e64402038a 459 Pfam PF02080 TrkA-C domain 155 221 6.3E-10 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 15 386 2.1E-126 T 06-07-2017 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 16 384 5.1E-98 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 Gene3D G3DSA:3.90.1150.10 256 387 2.0E-35 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 SUPERFAMILY SSF53383 24 385 3.5E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 PIRSF PIRSF001434 3 388 2.8E-116 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS07475 e3b4c54e069fb2d08414e3024520de1b 389 Gene3D G3DSA:3.40.640.10 8 253 2.0E-71 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 Pfam PF00575 S1 RNA binding domain 36 117 1.5E-11 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 Hamap MF_00970 Ribonuclease E [rne]. 1 1087 35.921 T 06-07-2017 IPR028878 Ribonuclease E GO:0006396|GO:0008995 CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 SUPERFAMILY SSF50249 39 124 1.83E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 Gene3D G3DSA:2.40.50.140 31 124 2.4E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 2.4E-157 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 SMART SM00316 37 118 2.0E-10 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS08300 6fd71c29934d8f429f8f8dd750aa4177 1099 Pfam PF10150 Ribonuclease E/G family 120 389 3.7E-91 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CAL12_RS27840 af84f7110cfde827744286987fd3add1 230 Pfam PF00583 Acetyltransferase (GNAT) family 144 216 4.3E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS27840 af84f7110cfde827744286987fd3add1 230 Gene3D G3DSA:3.40.630.30 117 223 4.6E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS27840 af84f7110cfde827744286987fd3add1 230 SUPERFAMILY SSF55729 41 222 3.09E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 SUPERFAMILY SSF52540 21 258 5.2E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 Pfam PF00005 ABC transporter 37 178 9.7E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 SMART SM00382 45 228 6.4E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 Pfam PF08402 TOBE domain 294 384 2.8E-10 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 Gene3D G3DSA:3.40.50.300 15 253 1.1E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23545 3d9f74f4190dff0b174c39b4a90a7b17 389 SUPERFAMILY SSF50331 254 384 3.57E-7 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 298 309 - T 06-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 SMART SM00981 159 257 2.9E-17 T 06-07-2017 IPR004114 THUMP domain GO:0003723 CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 Gene3D G3DSA:3.40.50.150 250 317 6.2E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 Gene3D G3DSA:3.40.50.150 354 470 6.2E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 Pfam PF01170 Putative RNA methylase family UPF0020 265 470 2.8E-48 T 06-07-2017 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 403 409 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 SUPERFAMILY SSF53335 249 320 7.91E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 SUPERFAMILY SSF53335 357 471 7.91E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08705 c432a596962c2f2d899fa821055eebf1 527 Pfam PF02926 THUMP domain 139 257 1.6E-8 T 06-07-2017 IPR004114 THUMP domain GO:0003723 CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 2.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.1E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 185 6.2E-4 T 06-07-2017 CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 Pfam PF00106 short chain dehydrogenase 3 189 3.2E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 SUPERFAMILY SSF51735 2 245 2.27E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06515 912fd93ba707f7b60e2008b76e825dd9 253 Gene3D G3DSA:3.40.50.720 2 247 1.1E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16025 a2859faa074d274e8c6f910bfc832b61 745 Pfam PF04185 Phosphoesterase family 49 468 1.9E-105 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS16025 a2859faa074d274e8c6f910bfc832b61 745 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 6 734 2.6E-257 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS16025 a2859faa074d274e8c6f910bfc832b61 745 Pfam PF05506 Domain of unknown function (DUF756) 539 622 6.9E-22 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS16025 a2859faa074d274e8c6f910bfc832b61 745 Pfam PF05506 Domain of unknown function (DUF756) 635 720 6.3E-13 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Gene3D G3DSA:1.10.540.10 4 119 3.5E-31 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 SUPERFAMILY SSF56645 6 241 1.7E-75 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Gene3D G3DSA:1.20.140.10 216 384 3.1E-62 T 06-07-2017 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 3.7E-27 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Gene3D G3DSA:2.40.110.10 121 215 2.4E-38 T 06-07-2017 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 382 1.2E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 117 1.3E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS14185 710b8640b1f30faf76056e92b4fcf614 386 SUPERFAMILY SSF47203 226 384 9.5E-53 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS26875 4fcdf75eee8e4af33a67be8cd957c864 260 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 24 252 1.5E-25 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS26875 4fcdf75eee8e4af33a67be8cd957c864 260 Gene3D G3DSA:3.40.50.970 13 257 3.8E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS26875 4fcdf75eee8e4af33a67be8cd957c864 260 SUPERFAMILY SSF52518 15 256 5.89E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 Pfam PF03466 LysR substrate binding domain 112 313 1.2E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 SUPERFAMILY SSF46785 20 136 3.81E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 Gene3D G3DSA:3.40.190.10 113 200 2.2E-15 T 06-07-2017 CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 SUPERFAMILY SSF53850 115 318 1.71E-32 T 06-07-2017 CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 Gene3D G3DSA:1.10.10.10 21 105 3.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 85 5.9E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25925 9c46cd76903ccfd4ae28b5202cfc0489 319 Gene3D G3DSA:3.40.190.10 201 285 3.3E-20 T 06-07-2017 CAL12_RS15420 9da0972a7ece09aab0ba324c6c0455dd 195 Gene3D G3DSA:3.90.1720.10 54 181 2.5E-47 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAL12_RS15420 9da0972a7ece09aab0ba324c6c0455dd 195 SUPERFAMILY SSF54001 51 180 2.84E-42 T 06-07-2017 CAL12_RS15420 9da0972a7ece09aab0ba324c6c0455dd 195 Pfam PF00877 NlpC/P60 family 70 178 3.4E-30 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 483 3.0E-165 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 SUPERFAMILY SSF55931 4 300 1.24E-116 T 06-07-2017 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 SUPERFAMILY SSF89095 301 406 1.06E-31 T 06-07-2017 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 Pfam PF02934 GatB/GatE catalytic domain 5 293 9.2E-109 T 06-07-2017 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 Pfam PF02637 GatB domain 332 483 4.2E-51 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 484 37.737 T 06-07-2017 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 SMART SM00845 332 483 2.5E-78 T 06-07-2017 IPR018027 Asn/Gln amidotransferase GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 06-07-2017 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CAL12_RS25320 621b768f244e9a7cda82c590beec52ca 484 Gene3D G3DSA:1.10.10.410 435 483 2.7E-5 T 06-07-2017 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CAL12_RS25940 cf3fd8deac73ab45b565ebf42bd6d770 214 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 205 7.9E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25940 cf3fd8deac73ab45b565ebf42bd6d770 214 SUPERFAMILY SSF161098 13 194 6.28E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25940 cf3fd8deac73ab45b565ebf42bd6d770 214 Gene3D G3DSA:1.10.3720.10 12 208 1.3E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25940 cf3fd8deac73ab45b565ebf42bd6d770 214 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 103 2.8E-22 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS12635 dc6e4c5629cfb82cf2ef9b51eed5a5fd 333 SUPERFAMILY SSF53474 207 298 3.81E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12635 dc6e4c5629cfb82cf2ef9b51eed5a5fd 333 SUPERFAMILY SSF53474 14 167 3.81E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12635 dc6e4c5629cfb82cf2ef9b51eed5a5fd 333 Gene3D G3DSA:3.40.50.1820 19 296 7.9E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12635 dc6e4c5629cfb82cf2ef9b51eed5a5fd 333 Pfam PF12146 Serine aminopeptidase, S33 34 282 2.3E-51 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 Pfam PF05036 Sporulation related domain 306 380 3.2E-14 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 88 177 6.8E-36 T 06-07-2017 IPR012997 Rare lipoprotein A CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 SUPERFAMILY SSF50685 74 175 5.58E-7 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 Gene3D G3DSA:3.30.70.1070 303 380 3.4E-14 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 SUPERFAMILY SSF110997 306 376 3.66E-13 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS01685 f00c17155823183f5d118d7e90398b0c 383 Pfam PF03330 Lytic transglycolase 85 174 3.7E-24 T 06-07-2017 IPR009009 RlpA-like protein, double-psi beta-barrel domain CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 Gene3D G3DSA:3.40.190.10 203 312 3.0E-36 T 06-07-2017 CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 PIRSF PIRSF002741 14 522 2.2E-95 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 444 1.3E-82 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 Gene3D G3DSA:3.10.105.10 313 493 1.7E-35 T 06-07-2017 CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 Gene3D G3DSA:3.90.76.10 56 202 2.3E-40 T 06-07-2017 CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 SUPERFAMILY SSF53850 43 523 5.25E-119 T 06-07-2017 CAL12_RS09820 61d98663bd8f867554a79b6181ef6ac8 523 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 95 116 - T 06-07-2017 IPR023765 Solute-binding protein family 5, conserved site CAL12_RS11685 af25446e0a68252ad26c3ef521adfa0f 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 06-07-2017 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CAL12_RS11685 af25446e0a68252ad26c3ef521adfa0f 66 SUPERFAMILY SSF55008 1 64 3.4E-16 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAL12_RS11685 af25446e0a68252ad26c3ef521adfa0f 66 Gene3D G3DSA:3.30.70.100 1 63 7.4E-21 T 06-07-2017 CAL12_RS11685 af25446e0a68252ad26c3ef521adfa0f 66 Pfam PF00403 Heavy-metal-associated domain 5 62 2.6E-13 T 06-07-2017 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 Pfam PF07687 Peptidase dimerisation domain 190 286 4.1E-7 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 SUPERFAMILY SSF53187 305 391 1.29E-86 T 06-07-2017 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 SUPERFAMILY SSF53187 8 202 1.29E-86 T 06-07-2017 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 PIRSF PIRSF005962 4 395 1.5E-125 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 SUPERFAMILY SSF55031 188 303 7.85E-28 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 Pfam PF01546 Peptidase family M20/M25/M40 78 390 9.8E-36 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 Gene3D G3DSA:3.40.630.10 305 391 4.2E-101 T 06-07-2017 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 Gene3D G3DSA:3.40.630.10 8 183 4.2E-101 T 06-07-2017 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 381 2.7E-113 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS22480 ed2f6784ae204b4ca24beddf5b5b0f19 397 Gene3D G3DSA:3.30.70.360 186 304 2.0E-38 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Gene3D G3DSA:1.10.540.10 7 120 1.1E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 7.8E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Gene3D G3DSA:2.40.110.10 122 219 2.1E-33 T 06-07-2017 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 119 7.4E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 379 1.3E-12 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 SUPERFAMILY SSF56645 7 241 2.88E-66 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 Gene3D G3DSA:1.20.140.10 220 382 1.7E-25 T 06-07-2017 CAL12_RS16270 89e39abb60af6a1796f295b611f40394 388 SUPERFAMILY SSF47203 229 383 8.7E-13 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 1.8E-163 T 06-07-2017 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SUPERFAMILY SSF54631 94 201 1.59E-26 T 06-07-2017 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 86.766 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SUPERFAMILY SSF51412 215 476 7.06E-127 T 06-07-2017 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SUPERFAMILY SSF51412 2 89 7.06E-127 T 06-07-2017 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SMART SM01240 6 472 0.0 T 06-07-2017 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 8.5E-191 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 06-07-2017 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 Gene3D G3DSA:3.20.20.70 4 484 3.8E-202 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SMART SM00116 156 204 9.5E-6 T 06-07-2017 IPR000644 CBS domain CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 SMART SM00116 95 142 4.2E-11 T 06-07-2017 IPR000644 CBS domain CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 PIRSF PIRSF000130 1 486 1.2E-204 T 06-07-2017 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 Pfam PF00571 CBS domain 95 138 3.9E-9 T 06-07-2017 IPR000644 CBS domain CAL12_RS17040 f3cd9ebaea64f562ff76009b5352aa87 486 Pfam PF00571 CBS domain 150 201 1.7E-4 T 06-07-2017 IPR000644 CBS domain CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 Pfam PF03466 LysR substrate binding domain 90 292 4.6E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 Gene3D G3DSA:1.10.10.10 1 85 8.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 Gene3D G3DSA:3.40.190.10 177 264 4.7E-23 T 06-07-2017 CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 Gene3D G3DSA:3.40.190.10 95 176 2.3E-13 T 06-07-2017 CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 SUPERFAMILY SSF46785 1 82 1.36E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24545 40d25e5e95a775181eeedc6c3b844294 312 SUPERFAMILY SSF53850 92 296 1.86E-33 T 06-07-2017 CAL12_RS21480 2f8774c33e2e72ad7bfeeb3918a42bef 313 Gene3D G3DSA:1.10.3720.10 98 307 1.6E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21480 2f8774c33e2e72ad7bfeeb3918a42bef 313 SUPERFAMILY SSF161098 96 299 6.54E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21480 2f8774c33e2e72ad7bfeeb3918a42bef 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 3.8E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 Gene3D G3DSA:3.30.70.360 189 283 3.8E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 Pfam PF07687 Peptidase dimerisation domain 176 282 5.6E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 11 385 2.6E-104 T 06-07-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 Gene3D G3DSA:3.40.630.10 9 188 7.5E-63 T 06-07-2017 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 Gene3D G3DSA:3.40.630.10 329 390 7.5E-63 T 06-07-2017 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 SUPERFAMILY SSF55031 180 285 8.52E-18 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 SUPERFAMILY SSF53187 9 179 3.83E-57 T 06-07-2017 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 SUPERFAMILY SSF53187 309 389 3.83E-57 T 06-07-2017 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 106 143 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS14505 9809577df5baa7020dd265e37cd962e6 396 Pfam PF01546 Peptidase family M20/M25/M40 72 385 1.7E-33 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 453 4.0E-91 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 9.0E-73 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Gene3D G3DSA:3.30.160.110 113 148 6.9E-17 T 06-07-2017 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 SUPERFAMILY SSF53790 212 459 2.22E-80 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 3.2E-17 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 221 235 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Gene3D G3DSA:3.40.50.720 1 111 1.1E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 4.5E-7 T 06-07-2017 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Gene3D G3DSA:3.40.1010.10 216 332 9.4E-44 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Hamap MF_01646 Siroheme synthase [cysG]. 1 462 49.015 T 06-07-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Pfam PF13241 Putative NAD(P)-binding 6 115 1.6E-27 T 06-07-2017 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Gene3D G3DSA:1.10.8.210 150 211 1.4E-16 T 06-07-2017 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Gene3D G3DSA:3.30.950.10 333 462 3.6E-48 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 PIRSF PIRSF036426 1 468 3.6E-191 T 06-07-2017 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 430 8.8E-51 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 SUPERFAMILY SSF75615 114 209 1.57E-24 T 06-07-2017 CAL12_RS04950 4e1e591d66ad75ac5399cd7c1e9f8784 472 SUPERFAMILY SSF51735 1 112 2.76E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.1E-46 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 Pfam PF01196 Ribosomal protein L17 20 116 4.9E-35 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 Gene3D G3DSA:3.90.1030.10 1 117 4.3E-50 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 SUPERFAMILY SSF64263 1 119 2.09E-50 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.988 T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27490 ea68b0f20e1c253b94802b88c513810b 130 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 06-07-2017 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS12055 a781acfc04455e7ecab2ab67bec1cae4 93 Gene3D G3DSA:1.20.58.380 1 73 3.3E-21 T 06-07-2017 CAL12_RS12055 a781acfc04455e7ecab2ab67bec1cae4 93 Pfam PF05400 Flagellar protein FliT 1 86 1.9E-22 T 06-07-2017 IPR008622 Flagellar protein FliT CAL12_RS01730 160b0ab618f6383cf2d3702d4af5974c 247 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 12 182 1.8E-38 T 06-07-2017 IPR010664 Lipopolysaccharide assembly, LptC-related CAL12_RS01730 160b0ab618f6383cf2d3702d4af5974c 247 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 185 4.9E-41 T 06-07-2017 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 CAL12_RS01730 160b0ab618f6383cf2d3702d4af5974c 247 Gene3D G3DSA:2.60.450.10 100 182 3.5E-5 T 06-07-2017 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 Gene3D G3DSA:3.30.70.360 242 328 1.9E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 Pfam PF01546 Peptidase family M20/M25/M40 85 412 1.2E-28 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 Gene3D G3DSA:3.40.630.10 361 420 9.0E-90 T 06-07-2017 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 Gene3D G3DSA:3.40.630.10 6 241 9.0E-90 T 06-07-2017 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 SUPERFAMILY SSF55031 229 329 1.79E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 PIRSF PIRSF001235 10 423 1.8E-100 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 Pfam PF07687 Peptidase dimerisation domain 226 325 5.9E-8 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 SUPERFAMILY SSF53187 346 419 4.65E-74 T 06-07-2017 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 SUPERFAMILY SSF53187 6 239 4.65E-74 T 06-07-2017 CAL12_RS25515 05c2e94a47ae1c07ec7555823dcc1e10 447 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 414 1.8E-95 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 SUPERFAMILY SSF52540 134 408 1.52E-91 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 Gene3D G3DSA:3.40.50.300 135 403 4.4E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 393 402 - T 06-07-2017 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 187 402 7.3E-70 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 33 481 4.4E-174 T 06-07-2017 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 SMART SM00382 199 386 1.0E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12010 eef62baa873478012df6a4072fb43bb1 489 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 40 480 6.4E-193 T 06-07-2017 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS03325 2d4e6ea8d214e83f9aa99f7af8c592f8 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 267 4.0E-46 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS03325 2d4e6ea8d214e83f9aa99f7af8c592f8 268 Gene3D G3DSA:1.10.12.10 211 267 3.2E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS03325 2d4e6ea8d214e83f9aa99f7af8c592f8 268 SUPERFAMILY SSF52096 18 267 1.15E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS03325 2d4e6ea8d214e83f9aa99f7af8c592f8 268 Gene3D G3DSA:3.90.226.10 20 207 6.7E-49 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 SUPERFAMILY SSF53850 101 310 7.76E-32 T 06-07-2017 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 Pfam PF03466 LysR substrate binding domain 98 309 5.3E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 Gene3D G3DSA:3.40.190.10 192 274 2.8E-12 T 06-07-2017 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 68 9.4E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 6.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 6.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 6.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 Gene3D G3DSA:1.10.10.10 11 94 1.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 Gene3D G3DSA:3.40.190.10 102 191 3.0E-11 T 06-07-2017 CAL12_RS02865 2138dc5e5854e33cf8fc3ba46473ab2f 328 SUPERFAMILY SSF46785 11 120 2.48E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 3.5E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 Gene3D G3DSA:3.40.190.10 83 187 2.6E-18 T 06-07-2017 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 Gene3D G3DSA:1.10.10.10 5 82 7.8E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 SUPERFAMILY SSF53850 91 286 2.01E-30 T 06-07-2017 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 SUPERFAMILY SSF46785 6 114 3.93E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 Gene3D G3DSA:3.40.190.10 188 240 2.5E-6 T 06-07-2017 CAL12_RS16695 2f09f16716d923c1764e8ab99b54e6f3 289 Pfam PF03466 LysR substrate binding domain 90 282 6.0E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS24490 f3f06b04b7b6671c9d9b758f628eeef0 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 254 6.3E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24490 f3f06b04b7b6671c9d9b758f628eeef0 267 Gene3D G3DSA:1.10.3720.10 56 255 1.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24490 f3f06b04b7b6671c9d9b758f628eeef0 267 SUPERFAMILY SSF161098 59 248 1.7E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 SUPERFAMILY SSF51717 6 274 8.77E-99 T 06-07-2017 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 19 34 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 19 272 7.7E-97 T 06-07-2017 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 53 66 - T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 Pfam PF00809 Pterin binding enzyme 20 258 2.5E-81 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS06555 02b2960473195bce3d839fcb1eabd4c1 291 Gene3D G3DSA:3.20.20.20 14 275 8.7E-108 T 06-07-2017 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SUPERFAMILY SSF52172 344 466 8.82E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Pfam PF01627 Hpt domain 501 580 9.2E-9 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SUPERFAMILY SSF47226 445 574 1.3E-15 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Gene3D G3DSA:3.40.50.2300 343 465 4.9E-30 T 06-07-2017 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Gene3D G3DSA:3.30.565.10 164 321 4.5E-39 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SUPERFAMILY SSF55874 153 321 1.57E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 269 279 6.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 6.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 PRINTS PR00344 Bacterial sensor protein C-terminal signature 251 265 6.4E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 211 322 5.8E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Pfam PF00072 Response regulator receiver domain 348 462 8.1E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Gene3D G3DSA:1.20.120.160 482 577 1.3E-11 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SMART SM00387 210 327 2.7E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SMART SM00388 97 163 5.3E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SUPERFAMILY SSF47384 82 164 1.65E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 SMART SM00448 346 462 6.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Gene3D G3DSA:1.10.287.130 89 159 2.1E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21330 ae7786ed63f0ae0d8592f35626009b74 605 Pfam PF00512 His Kinase A (phospho-acceptor) domain 97 163 8.6E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 113 2.0E-33 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 Gene3D G3DSA:3.10.20.30 3 107 1.3E-39 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 8.2E-10 T 06-07-2017 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 SUPERFAMILY SSF46548 108 236 8.89E-40 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 SUPERFAMILY SSF54292 5 107 4.51E-30 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 Gene3D G3DSA:1.10.1060.10 108 236 6.0E-49 T 06-07-2017 CAL12_RS19255 3c2e670c4b3a503df6a83d49ca509734 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 230 1.0E-85 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS02500 feb1c63db16fc4fed91a9dcf78f26faf 309 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 54 304 5.7E-41 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS02500 feb1c63db16fc4fed91a9dcf78f26faf 309 SUPERFAMILY SSF51197 38 306 3.89E-59 T 06-07-2017 CAL12_RS02500 feb1c63db16fc4fed91a9dcf78f26faf 309 Gene3D G3DSA:3.60.130.10 30 306 2.3E-58 T 06-07-2017 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 SUPERFAMILY SSF51182 18 100 9.79E-6 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 279 321 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 Gene3D G3DSA:1.10.10.60 223 279 9.8E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 SUPERFAMILY SSF46689 278 325 2.9E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 Gene3D G3DSA:1.10.10.60 280 325 2.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 SUPERFAMILY SSF46689 225 276 4.35E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 Gene3D G3DSA:2.60.120.280 43 100 8.1E-6 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 SMART SM00342 242 325 1.7E-30 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 Pfam PF12852 Cupin 21 210 7.8E-34 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAL12_RS27890 b9afcd25aa99c8ef5b9b4d8c952d10ab 331 Pfam PF12833 Helix-turn-helix domain 248 325 6.5E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21615 f93117827fdca51cc8c9a7f1f928b275 95 SUPERFAMILY SSF51182 19 85 5.09E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS21615 f93117827fdca51cc8c9a7f1f928b275 95 Pfam PF07883 Cupin domain 23 84 9.0E-9 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS21615 f93117827fdca51cc8c9a7f1f928b275 95 Gene3D G3DSA:2.60.120.10 19 85 5.5E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS18695 05c14a0de86358d64b09a6c15ed0106d 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.378 T 06-07-2017 IPR022894 Oligoribonuclease GO:0016788 CAL12_RS18695 05c14a0de86358d64b09a6c15ed0106d 181 Gene3D G3DSA:3.30.420.10 4 180 4.0E-73 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS18695 05c14a0de86358d64b09a6c15ed0106d 181 SMART SM00479 7 180 1.1E-24 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAL12_RS18695 05c14a0de86358d64b09a6c15ed0106d 181 Pfam PF00929 Exonuclease 9 170 2.4E-32 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAL12_RS18695 05c14a0de86358d64b09a6c15ed0106d 181 SUPERFAMILY SSF53098 1 180 2.73E-48 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS19210 728e157fe44daa93d6639f20ad6b7a2e 363 Gene3D G3DSA:3.40.50.300 41 171 2.8E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19210 728e157fe44daa93d6639f20ad6b7a2e 363 Pfam PF03969 AFG1-like ATPase 3 354 4.9E-128 T 06-07-2017 IPR005654 ATPase, AFG1-like GO:0005524 CAL12_RS19210 728e157fe44daa93d6639f20ad6b7a2e 363 SUPERFAMILY SSF52540 44 191 5.88E-17 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 SUPERFAMILY SSF55486 30 165 9.03E-38 T 06-07-2017 CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 13 163 20.628 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 129 139 - T 06-07-2017 IPR020549 Endoribonuclease YbeY, conserved site CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 Gene3D G3DSA:3.40.390.30 16 162 5.1E-41 T 06-07-2017 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 Pfam PF02130 Uncharacterized protein family UPF0054 35 157 5.0E-30 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAL12_RS04865 8bf21b97cfda7535515b8e1825b32344 168 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 57 159 1.8E-29 T 06-07-2017 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 Gene3D G3DSA:3.40.309.10 265 441 1.8E-51 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 SUPERFAMILY SSF53720 3 478 1.27E-128 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 Gene3D G3DSA:3.40.605.10 5 264 4.9E-69 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS05815 91a85fef7726ef17fbd3dc164e123db4 482 Pfam PF00171 Aldehyde dehydrogenase family 24 475 2.0E-130 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS13270 4a40529cf12c7e53c0dfd661dddea6c5 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 329 8.9E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13270 4a40529cf12c7e53c0dfd661dddea6c5 333 Gene3D G3DSA:3.40.190.10 137 247 6.8E-4 T 06-07-2017 CAL12_RS13270 4a40529cf12c7e53c0dfd661dddea6c5 333 PIRSF PIRSF017082 4 332 5.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13270 4a40529cf12c7e53c0dfd661dddea6c5 333 SUPERFAMILY SSF53850 125 291 6.73E-12 T 06-07-2017 CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 Gene3D G3DSA:3.30.70.240 130 193 2.2E-11 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 7.5E-27 T 06-07-2017 IPR001498 Impact, N-terminal CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 SUPERFAMILY SSF54980 129 191 1.51E-9 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 Pfam PF09186 Domain of unknown function (DUF1949) 132 188 6.2E-12 T 06-07-2017 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 SUPERFAMILY SSF54211 5 123 1.9E-39 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS10945 c95559eefcc1744437d277e8069841cd 198 Gene3D G3DSA:3.30.230.30 4 123 5.5E-44 T 06-07-2017 IPR001498 Impact, N-terminal CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 Gene3D G3DSA:1.10.10.10 2 85 9.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 Pfam PF03466 LysR substrate binding domain 89 275 9.9E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 Gene3D G3DSA:3.40.190.10 89 180 8.4E-20 T 06-07-2017 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 Gene3D G3DSA:3.40.190.10 181 261 6.0E-26 T 06-07-2017 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 SUPERFAMILY SSF53850 90 275 4.35E-36 T 06-07-2017 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 SUPERFAMILY SSF46785 2 85 1.43E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20760 1ab1749f1ff08b0abe64cc73a32a0889 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 Gene3D G3DSA:3.40.50.1770 190 366 3.5E-33 T 06-07-2017 CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 SMART SM01002 148 310 7.0E-65 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 SUPERFAMILY SSF51735 139 315 7.9E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 364 1.5E-59 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 SUPERFAMILY SSF52283 5 170 6.63E-40 T 06-07-2017 CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 7 139 9.6E-38 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 SMART SM01003 6 139 4.9E-51 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAL12_RS21205 8ae35a963f729aa7fd129bbb2861fefa 382 Gene3D G3DSA:3.40.50.1770 5 189 9.8E-53 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 PIRSF PIRSF036298 1 288 1.4E-151 T 06-07-2017 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Gene3D G3DSA:3.30.70.20 32 110 1.3E-12 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 SUPERFAMILY SSF54862 29 264 1.36E-70 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Gene3D G3DSA:1.20.5.480 252 288 5.1E-20 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 287 7.6E-141 T 06-07-2017 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Gene3D G3DSA:3.30.70.20 111 152 4.0E-21 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Gene3D G3DSA:3.30.70.20 153 251 8.5E-30 T 06-07-2017 CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 288 2.5E-22 T 06-07-2017 IPR015246 Formate dehydrogenase, transmembrane CAL12_RS19435 c083203939723e0a198f6aaf72128335 288 Pfam PF13247 4Fe-4S dicluster domain 92 188 8.9E-24 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 Gene3D G3DSA:3.40.50.1860 155 255 7.0E-22 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 SUPERFAMILY SSF53681 42 152 1.96E-28 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 SUPERFAMILY SSF53681 156 267 1.57E-21 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 TIGRFAM TIGR00035 asp_race: aspartate racemase 42 266 9.5E-47 T 06-07-2017 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 Pfam PF01177 Asp/Glu/Hydantoin racemase 45 262 1.4E-57 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS12300 6f1098a1adb4f352a6cca2a8ae65321e 270 Gene3D G3DSA:3.40.50.1860 42 154 5.3E-36 T 06-07-2017 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 Pfam PF02562 PhoH-like protein 354 556 3.1E-52 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 Gene3D G3DSA:3.40.50.1010 209 264 2.1E-9 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 Gene3D G3DSA:3.40.50.1010 114 172 2.1E-9 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 SUPERFAMILY SSF52540 226 290 2.56E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 SUPERFAMILY SSF52540 353 548 2.56E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 SUPERFAMILY SSF88723 112 173 7.26E-11 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 SUPERFAMILY SSF88723 209 260 7.26E-11 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 Gene3D G3DSA:3.40.50.300 351 566 1.0E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 SMART SM00670 112 246 4.9E-13 T 06-07-2017 IPR002716 PIN domain CAL12_RS18245 8c72508c97d004ee3d4e2033caf36ff3 568 Pfam PF13638 PIN domain 114 258 3.1E-38 T 06-07-2017 IPR002716 PIN domain CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Pfam PF02803 Thiolase, C-terminal domain 276 398 3.7E-44 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Pfam PF00108 Thiolase, N-terminal domain 9 268 8.1E-72 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Gene3D G3DSA:3.40.47.10 7 130 3.9E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Gene3D G3DSA:3.40.47.10 191 282 3.9E-69 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Gene3D G3DSA:3.40.47.10 148 190 8.3E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 Gene3D G3DSA:3.40.47.10 283 398 8.3E-67 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 06-07-2017 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 SUPERFAMILY SSF53901 277 398 3.52E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 PIRSF PIRSF000429 2 399 2.7E-128 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 7.3E-139 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS27040 f8aaa31b28ad7a361d9ab98d151a9c56 399 SUPERFAMILY SSF53901 7 276 4.8E-74 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 Gene3D G3DSA:3.40.50.720 1 251 5.9E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 200 2.7E-6 T 06-07-2017 CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 5.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 5.8E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 SUPERFAMILY SSF51735 1 253 1.15E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 245 1.9E-41 T 06-07-2017 CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24410 1aa6bbeeecaa9ac1da754fdc7de6a478 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 8.4E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 Gene3D G3DSA:1.10.10.60 290 338 1.3E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 Gene3D G3DSA:1.10.10.60 233 289 2.6E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 SUPERFAMILY SSF46689 236 282 1.12E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 SUPERFAMILY SSF46689 288 339 4.93E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 SMART SM00342 252 335 6.7E-13 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 SUPERFAMILY SSF52317 20 215 2.38E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 Pfam PF01965 DJ-1/PfpI family 20 195 1.0E-20 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 Pfam PF12833 Helix-turn-helix domain 258 337 6.9E-14 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01300 21e760068c60e8ab6c6b6ddda670777b 346 Gene3D G3DSA:3.40.50.880 20 215 1.0E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 SUPERFAMILY SSF53187 367 441 6.0E-69 T 06-07-2017 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 SUPERFAMILY SSF53187 211 255 6.0E-69 T 06-07-2017 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 SUPERFAMILY SSF53187 3 182 6.0E-69 T 06-07-2017 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 Pfam PF07687 Peptidase dimerisation domain 251 343 1.1E-5 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 36 433 2.0E-95 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 Gene3D G3DSA:3.30.70.360 261 360 1.0E-35 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 Pfam PF01546 Peptidase family M20/M25/M40 85 437 3.7E-22 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 SUPERFAMILY SSF55031 247 360 3.66E-27 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 Gene3D G3DSA:3.40.630.10 6 260 8.5E-87 T 06-07-2017 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 Gene3D G3DSA:3.40.630.10 382 441 8.5E-87 T 06-07-2017 CAL12_RS00515 9fb6242708d24775697c3510b96c6c21 447 PIRSF PIRSF001235 6 445 1.0E-110 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 Gene3D G3DSA:2.30.40.10 353 378 2.9E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 SUPERFAMILY SSF51556 58 368 2.54E-91 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 Gene3D G3DSA:3.20.20.140 60 352 2.9E-95 T 06-07-2017 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 Gene3D G3DSA:2.30.40.10 379 410 9.6E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 Gene3D G3DSA:2.30.40.10 2 59 9.6E-25 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 SUPERFAMILY SSF51338 2 57 8.64E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 SUPERFAMILY SSF51338 351 409 7.85E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01370 675f1ed041e5fce0344ef1695fd42c47 415 Pfam PF01979 Amidohydrolase family 54 408 8.9E-42 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 SUPERFAMILY SSF158544 134 261 8.37E-6 T 06-07-2017 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 PIRSF PIRSF002786 19 364 5.8E-59 T 06-07-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 SUPERFAMILY SSF54523 324 359 7.69E-7 T 06-07-2017 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 SUPERFAMILY SSF54523 63 105 7.69E-7 T 06-07-2017 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 Gene3D G3DSA:3.30.1300.30 325 361 4.1E-6 T 06-07-2017 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 Gene3D G3DSA:3.30.1300.30 59 121 4.1E-6 T 06-07-2017 CAL12_RS27330 4fcda99720245e2083677345e900c77b 364 Pfam PF03934 Type II secretion system (T2SS), protein K 54 352 1.5E-56 T 06-07-2017 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 Pfam PF03167 Uracil DNA glycosylase superfamily 338 485 2.8E-36 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 TIGRFAM TIGR03915 SAM_7_link_chp: probable DNA metabolism protein 11 271 2.5E-52 T 06-07-2017 IPR023875 DNA metabolism protein, putative CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 SMART SM00986 337 492 1.3E-31 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 Pfam PF13566 Domain of unknown function (DUF4130 109 271 3.5E-35 T 06-07-2017 IPR025404 Domain of unknown function DUF4130 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 SMART SM00987 337 492 1.3E-31 T 06-07-2017 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 Gene3D G3DSA:3.40.470.10 319 491 1.6E-55 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 274 491 9.5E-72 T 06-07-2017 IPR005273 Uracil-DNA glycosylase, family 4 domain CAL12_RS04195 89f46170baff90d0bb6a7b9ca8fde95c 507 SUPERFAMILY SSF52141 319 488 5.56E-47 T 06-07-2017 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.0E-6 T 06-07-2017 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.0E-6 T 06-07-2017 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 Gene3D G3DSA:3.50.50.60 425 485 3.5E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 Gene3D G3DSA:3.50.50.60 4 261 3.5E-68 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 Pfam PF00890 FAD binding domain 102 466 8.5E-35 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 Pfam PF00890 FAD binding domain 10 53 8.1E-9 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 SUPERFAMILY SSF51905 5 267 2.77E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 SUPERFAMILY SSF51905 428 484 2.77E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 SUPERFAMILY SSF56425 266 423 2.51E-21 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS13315 4d1b8f7db18c683fba5e4b8c459e6a80 487 Gene3D G3DSA:3.90.700.10 283 418 7.6E-20 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 Gene3D G3DSA:1.10.10.10 1 79 4.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 Gene3D G3DSA:3.40.190.10 177 267 1.6E-30 T 06-07-2017 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 Pfam PF03466 LysR substrate binding domain 87 292 4.4E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 SUPERFAMILY SSF53850 88 294 1.09E-38 T 06-07-2017 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 SUPERFAMILY SSF46785 1 78 1.91E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.0E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04545 af49a8ff853d08a9818b7f9823bbef79 296 Gene3D G3DSA:3.40.190.10 88 176 3.7E-25 T 06-07-2017 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 Pfam PF00633 Helix-hairpin-helix motif 100 127 2.3E-8 T 06-07-2017 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 167 1.4E-19 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 TIGRFAM TIGR01083 nth: endonuclease III 5 194 9.3E-83 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 PIRSF PIRSF001435 1 212 2.4E-50 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 Gene3D G3DSA:1.10.340.30 22 122 5.7E-35 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 SMART SM00478 38 185 1.5E-57 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 SUPERFAMILY SSF48150 3 209 1.37E-73 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 SMART SM00525 186 206 1.9E-4 T 06-07-2017 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.272 T 06-07-2017 IPR005759 Endonuclease III GO:0003906|GO:0006284 CAL12_RS08210 e29253f32ee63f840416762f75f1ccb1 214 Gene3D G3DSA:1.10.1670.10 123 208 1.8E-35 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 4 447 2.7E-112 T 06-07-2017 IPR017830 Squalene-associated FAD-dependent desaturase CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 Pfam PF01593 Flavin containing amine oxidoreductase 11 447 1.6E-26 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 Gene3D G3DSA:3.50.50.60 407 451 2.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 Gene3D G3DSA:3.50.50.60 215 293 2.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 Gene3D G3DSA:3.50.50.60 2 39 2.7E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 SUPERFAMILY SSF51905 407 449 4.75E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18195 91ac7656bd1ac770daebc69eddc9bb17 457 SUPERFAMILY SSF51905 1 302 4.75E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07145 77b5ff34bea08936b41d8b9bd93cadb9 288 SUPERFAMILY SSF56281 32 270 3.25E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07145 77b5ff34bea08936b41d8b9bd93cadb9 288 SMART SM00849 33 256 6.7E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07145 77b5ff34bea08936b41d8b9bd93cadb9 288 Gene3D G3DSA:3.60.15.10 1 272 9.8E-34 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07145 77b5ff34bea08936b41d8b9bd93cadb9 288 Pfam PF00753 Metallo-beta-lactamase superfamily 34 234 5.6E-20 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07915 ffc89aa24dcafefd894af6fb706e89e6 108 Gene3D G3DSA:3.30.70.900 1 107 2.4E-19 T 06-07-2017 CAL12_RS07915 ffc89aa24dcafefd894af6fb706e89e6 108 SUPERFAMILY SSF54909 1 106 1.07E-27 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS07915 ffc89aa24dcafefd894af6fb706e89e6 108 Pfam PF07978 NIPSNAP 3 105 6.1E-26 T 06-07-2017 IPR012577 NIPSNAP CAL12_RS02030 deb3603251b9085e8f4c4b837b230e8d 145 Pfam PF05899 Protein of unknown function (DUF861) 66 138 1.7E-17 T 06-07-2017 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 CAL12_RS02030 deb3603251b9085e8f4c4b837b230e8d 145 Gene3D G3DSA:2.60.120.10 45 141 3.8E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS02030 deb3603251b9085e8f4c4b837b230e8d 145 SUPERFAMILY SSF51182 47 141 1.39E-17 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS16085 d476895b04b20b2536afa3ba7403a9c7 273 Gene3D G3DSA:3.40.190.10 99 220 3.1E-4 T 06-07-2017 CAL12_RS16085 d476895b04b20b2536afa3ba7403a9c7 273 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 61 257 4.0E-22 T 06-07-2017 CAL12_RS16085 d476895b04b20b2536afa3ba7403a9c7 273 SUPERFAMILY SSF53850 60 240 4.71E-13 T 06-07-2017 CAL12_RS26755 e7337759bf5667b95a1ba18ae13c9b75 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 24 178 3.0E-49 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAL12_RS26755 e7337759bf5667b95a1ba18ae13c9b75 187 Gene3D G3DSA:1.20.1200.10 17 182 9.8E-62 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAL12_RS26755 e7337759bf5667b95a1ba18ae13c9b75 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 179 6.0E-61 T 06-07-2017 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAL12_RS26755 e7337759bf5667b95a1ba18ae13c9b75 187 Pfam PF01923 Cobalamin adenosyltransferase 8 166 2.6E-55 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAL12_RS26755 e7337759bf5667b95a1ba18ae13c9b75 187 SUPERFAMILY SSF89028 8 179 1.43E-57 T 06-07-2017 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SMART SM00895 165 292 1.3E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SMART SM00345 17 75 5.3E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SMART SM00345 93 153 0.092 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Pfam PF07729 FCD domain 165 291 1.0E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Gene3D G3DSA:1.20.120.530 164 295 5.1E-18 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SUPERFAMILY SSF46785 9 79 5.39E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SUPERFAMILY SSF48008 164 295 9.15E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 116 152 3.0E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 75 4.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 SUPERFAMILY SSF46785 115 154 7.11E-5 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Gene3D G3DSA:1.10.10.10 4 75 2.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08555 76b9684d34827a0588356a2fa3b1dfe1 297 Gene3D G3DSA:1.10.10.10 94 152 2.5E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01155 3ac48cada0b0077c0345eb2fc726f429 155 SUPERFAMILY SSF46785 12 151 2.68E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01155 3ac48cada0b0077c0345eb2fc726f429 155 Pfam PF01047 MarR family 45 103 8.5E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS01155 3ac48cada0b0077c0345eb2fc726f429 155 Gene3D G3DSA:1.10.10.10 18 148 3.6E-33 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01155 3ac48cada0b0077c0345eb2fc726f429 155 SMART SM00347 38 138 7.4E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS07755 736c848ba35c917e9dcf1db1e305cb4e 250 SUPERFAMILY SSF161098 2 240 1.44E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07755 736c848ba35c917e9dcf1db1e305cb4e 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 247 2.6E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07755 736c848ba35c917e9dcf1db1e305cb4e 250 Gene3D G3DSA:1.10.3720.10 54 242 4.6E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.2E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 SUPERFAMILY SSF53850 91 296 3.57E-39 T 06-07-2017 CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 Gene3D G3DSA:1.10.10.10 3 88 3.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 SUPERFAMILY SSF46785 4 87 2.45E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 Pfam PF03466 LysR substrate binding domain 90 294 4.9E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 Gene3D G3DSA:3.40.190.10 93 178 2.2E-22 T 06-07-2017 CAL12_RS25660 f90c53c0d54c48ab654416544c2a3b62 298 Gene3D G3DSA:3.40.190.10 179 263 1.3E-14 T 06-07-2017 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 PIRSF PIRSF002756 6 339 4.1E-108 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 336 7.2E-125 T 06-07-2017 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 Gene3D G3DSA:3.40.190.10 179 335 7.2E-30 T 06-07-2017 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 SUPERFAMILY SSF53850 27 337 3.03E-97 T 06-07-2017 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 Gene3D G3DSA:3.40.190.10 26 166 3.2E-53 T 06-07-2017 CAL12_RS06580 523b2e9da11b85e40aa5318c2fb6631b 346 Pfam PF12849 PBP superfamily domain 24 306 1.2E-60 T 06-07-2017 IPR024370 PBP domain CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 SUPERFAMILY SSF64518 1 308 8.89E-45 T 06-07-2017 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 3 510 3.7E-79 T 06-07-2017 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 1.6E-17 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 Gene3D G3DSA:1.20.1330.10 57 139 1.5E-13 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 Gene3D G3DSA:1.20.1330.10 418 463 1.5E-13 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 Gene3D G3DSA:1.20.1330.10 286 287 1.5E-13 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11940 c9622a890799c250501da276bbaa0f37 514 SUPERFAMILY SSF64518 296 511 1.96E-21 T 06-07-2017 CAL12_RS14635 c173e739aca57cabdf29fe4a783ac9d7 501 Pfam PF07171 MlrC C-terminus 303 480 6.8E-58 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS14635 c173e739aca57cabdf29fe4a783ac9d7 501 Pfam PF07364 Metallopeptidase family M81 4 291 1.4E-94 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS14635 c173e739aca57cabdf29fe4a783ac9d7 501 PIRSF PIRSF012702 2 497 2.2E-165 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.783 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 Gene3D G3DSA:3.30.230.40 1 88 1.2E-38 T 06-07-2017 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 Gene3D G3DSA:3.30.230.40 90 195 3.9E-31 T 06-07-2017 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 SUPERFAMILY SSF54211 87 179 1.64E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 3.8E-64 T 06-07-2017 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 06-07-2017 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CAL12_RS00830 13566b7d496700061c0ed1be1aeec85a 195 SUPERFAMILY SSF54211 1 86 4.43E-34 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS26495 88b71cde4e9cb80f9951ea55da88915f 239 PIRSF PIRSF004848 1 238 2.7E-71 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAL12_RS26495 88b71cde4e9cb80f9951ea55da88915f 239 Gene3D G3DSA:3.20.20.10 3 236 7.5E-90 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS26495 88b71cde4e9cb80f9951ea55da88915f 239 Pfam PF01168 Alanine racemase, N-terminal domain 13 233 1.8E-25 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS26495 88b71cde4e9cb80f9951ea55da88915f 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 9 233 2.9E-56 T 06-07-2017 IPR011078 Uncharacterised protein family UPF0001 CAL12_RS26495 88b71cde4e9cb80f9951ea55da88915f 239 SUPERFAMILY SSF51419 5 231 1.2E-73 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS26750 f11bbd19b003268bfe51eadf1dcd3162 155 SUPERFAMILY SSF55729 2 133 5.83E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS26750 f11bbd19b003268bfe51eadf1dcd3162 155 Gene3D G3DSA:3.40.630.30 1 141 2.5E-47 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS26750 f11bbd19b003268bfe51eadf1dcd3162 155 Pfam PF00583 Acetyltransferase (GNAT) family 57 121 8.3E-15 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 SUPERFAMILY SSF46626 207 283 3.58E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 SUPERFAMILY SSF46626 331 375 3.58E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 SUPERFAMILY SSF46626 416 459 3.58E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 Gene3D G3DSA:1.10.760.10 49 218 3.4E-31 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 Gene3D G3DSA:1.10.760.10 219 368 1.7E-34 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 Gene3D G3DSA:1.10.760.10 438 463 1.7E-34 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 Pfam PF03150 Di-haem cytochrome c peroxidase 54 230 4.2E-34 T 06-07-2017 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CAL12_RS18835 2a47b4aeeac298835031aea01a208a23 477 SUPERFAMILY SSF46626 42 215 3.18E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 PRINTS PR01008 Flagellar L-ring protein signature 221 235 1.7E-27 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 PRINTS PR01008 Flagellar L-ring protein signature 205 219 1.7E-27 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 PRINTS PR01008 Flagellar L-ring protein signature 86 98 1.7E-27 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 PRINTS PR01008 Flagellar L-ring protein signature 158 173 1.7E-27 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 PRINTS PR01008 Flagellar L-ring protein signature 184 200 1.7E-27 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 Hamap MF_00415 Flagellar L-ring protein [flgH]. 15 242 25.679 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS11920 11bf11f8697996fdf29b5c09c87b879f 244 Pfam PF02107 Flagellar L-ring protein 64 240 1.6E-55 T 06-07-2017 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 SUPERFAMILY SSF46689 419 495 1.25E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 SMART SM00448 2 113 1.4E-30 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Gene3D G3DSA:1.10.8.60 315 388 3.3E-24 T 06-07-2017 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Pfam PF00072 Response regulator receiver domain 4 113 5.5E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 SUPERFAMILY SSF52540 146 385 1.17E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Gene3D G3DSA:3.40.50.2300 3 121 1.8E-32 T 06-07-2017 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Pfam PF02954 Bacterial regulatory protein, Fis family 453 490 5.0E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 SMART SM00382 162 305 5.2E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 06-07-2017 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 SUPERFAMILY SSF52172 2 186 1.57E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 475 495 4.5E-9 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 458 475 4.5E-9 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Gene3D G3DSA:1.10.10.60 425 495 4.3E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Pfam PF00158 Sigma-54 interaction domain 145 308 8.7E-68 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 355 364 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 492 3.5E-203 T 06-07-2017 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 CAL12_RS15310 7f9f6d5af222257605ab468cb8077303 497 Gene3D G3DSA:3.40.50.300 145 314 3.3E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 33.39 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 06-07-2017 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 SMART SM00934 17 257 1.3E-45 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 18 248 3.3E-30 T 06-07-2017 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 Gene3D G3DSA:3.20.20.70 6 269 1.6E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 SUPERFAMILY SSF51366 2 268 1.16E-72 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS02990 440e708fbf1cc50c6cfa8e4a933c54d0 272 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 252 8.0E-70 T 06-07-2017 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 CAL12_RS12035 80b6f97d28cc80ebf02600ae846f1168 387 Pfam PF00563 EAL domain 123 355 2.1E-72 T 06-07-2017 IPR001633 EAL domain CAL12_RS12035 80b6f97d28cc80ebf02600ae846f1168 387 SUPERFAMILY SSF141868 122 366 3.53E-89 T 06-07-2017 IPR001633 EAL domain CAL12_RS12035 80b6f97d28cc80ebf02600ae846f1168 387 SMART SM00052 117 360 8.0E-116 T 06-07-2017 IPR001633 EAL domain CAL12_RS12035 80b6f97d28cc80ebf02600ae846f1168 387 Gene3D G3DSA:3.20.20.450 121 363 1.1E-96 T 06-07-2017 IPR001633 EAL domain CAL12_RS07305 fad5bc202421a4caf0efe78ba4fc8c1a 254 SUPERFAMILY SSF161098 54 238 1.83E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07305 fad5bc202421a4caf0efe78ba4fc8c1a 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 246 2.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07305 fad5bc202421a4caf0efe78ba4fc8c1a 254 Gene3D G3DSA:1.10.3720.10 53 248 1.8E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25270 b5a2c4194fde04482bb03bda243571bb 213 Pfam PF03975 CheD chemotactic sensory transduction 64 166 1.9E-32 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CAL12_RS25270 b5a2c4194fde04482bb03bda243571bb 213 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 17 170 29.529 T 06-07-2017 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 CAL12_RS25270 b5a2c4194fde04482bb03bda243571bb 213 SUPERFAMILY SSF64438 22 170 1.1E-49 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAL12_RS09515 8ffb839123511da952e5c33740258be3 239 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 3.0E-71 T 06-07-2017 IPR022301 Integral membrane protein YjbE CAL12_RS09515 8ffb839123511da952e5c33740258be3 239 Pfam PF03741 Integral membrane protein TerC family 14 190 2.1E-44 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Pfam PF04060 Putative Fe-S cluster 14 46 1.4E-14 T 06-07-2017 IPR007202 4Fe-4S domain GO:0051536 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Pfam PF14697 4Fe-4S dicluster domain 79 133 6.4E-17 T 06-07-2017 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Gene3D G3DSA:3.30.70.20 18 46 2.8E-4 T 06-07-2017 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Gene3D G3DSA:3.30.70.20 87 97 2.8E-4 T 06-07-2017 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Gene3D G3DSA:3.30.70.20 98 138 9.5E-15 T 06-07-2017 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 4 138 9.0E-62 T 06-07-2017 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 Gene3D G3DSA:1.10.1060.10 55 86 6.0E-5 T 06-07-2017 CAL12_RS08215 771d004823fc64c1b913ff4efd73c917 202 SUPERFAMILY SSF54862 9 135 4.97E-27 T 06-07-2017 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 SMART SM00382 35 235 5.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 SMART SM00382 311 502 1.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 ProSitePatterns PS00211 ABC transporters family signature. 425 439 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Pfam PF00005 ABC transporter 27 185 4.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Pfam PF00005 ABC transporter 302 452 7.8E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Gene3D G3DSA:3.40.50.300 8 259 1.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Gene3D G3DSA:3.40.50.300 275 526 4.4E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 268 7.2E-7 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 504 536 8.5E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 SUPERFAMILY SSF52540 279 524 1.67E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03060 dc7d108fd5f91d85faa503a5d6975338 555 SUPERFAMILY SSF52540 8 258 7.28E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 Gene3D G3DSA:3.40.190.10 188 253 1.0E-6 T 06-07-2017 CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 Pfam PF03466 LysR substrate binding domain 86 286 5.0E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 SUPERFAMILY SSF46785 1 107 7.62E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 SUPERFAMILY SSF53850 87 291 1.96E-26 T 06-07-2017 CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 57 1.0E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 Gene3D G3DSA:3.40.190.10 87 187 1.2E-21 T 06-07-2017 CAL12_RS03370 ab4ed95334a53966c198d7629114de20 297 Gene3D G3DSA:1.10.10.10 1 78 6.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04730 306b01f94fbe8fd76cc24e1d7cedcaf8 270 Gene3D G3DSA:3.20.20.140 11 269 9.4E-65 T 06-07-2017 CAL12_RS04730 306b01f94fbe8fd76cc24e1d7cedcaf8 270 SUPERFAMILY SSF51556 13 268 5.11E-56 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS04730 306b01f94fbe8fd76cc24e1d7cedcaf8 270 Pfam PF04909 Amidohydrolase 13 269 5.1E-29 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Pfam PF13844 Glycosyl transferase family 41 435 620 2.4E-17 T 06-07-2017 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Pfam PF13844 Glycosyl transferase family 41 266 413 3.7E-18 T 06-07-2017 IPR029489 O-GlcNAc transferase, C-terminal Reactome: R-HSA-3214847 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SUPERFAMILY SSF53448 980 1185 5.16E-33 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SUPERFAMILY SSF53756 267 595 1.78E-11 T 06-07-2017 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Pfam PF13432 Tetratricopeptide repeat 30 76 4.1E-4 T 06-07-2017 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Gene3D G3DSA:3.90.550.10 980 1188 1.3E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SMART SM00028 179 212 1.4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SMART SM00028 110 143 0.11 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SMART SM00028 42 75 0.061 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SMART SM00028 76 109 290.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Pfam PF13181 Tetratricopeptide repeat 183 212 0.0011 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 SUPERFAMILY SSF48452 40 212 2.16E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Pfam PF00535 Glycosyl transferase family 2 980 1098 7.8E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS11785 bc751cf559d22a0f616b2c131c4192d6 1240 Gene3D G3DSA:1.25.40.10 31 248 1.3E-31 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 25 203 6.5E-52 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 Pfam PF01968 Hydantoinase/oxoprolinase 224 516 1.6E-85 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 Pfam PF02538 Hydantoinase B/oxoprolinase 735 1251 3.6E-133 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 SUPERFAMILY SSF53067 25 98 2.82E-9 T 06-07-2017 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 SUPERFAMILY SSF53067 282 366 2.82E-9 T 06-07-2017 CAL12_RS20075 ac6a4be12e81de842c151f398572a72d 1291 SUPERFAMILY SSF53067 424 512 2.82E-9 T 06-07-2017 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 SUPERFAMILY SSF50621 228 349 3.84E-44 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 SMART SM01005 232 355 1.5E-65 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 Gene3D G3DSA:2.40.37.10 215 354 3.8E-53 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 Gene3D G3DSA:3.20.20.10 11 214 3.6E-65 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 Hamap MF_01201 Alanine racemase. 2 355 33.73 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 06-07-2017 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 TIGRFAM TIGR00492 alr: alanine racemase 3 351 1.4E-103 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 Pfam PF01168 Alanine racemase, N-terminal domain 9 221 9.5E-63 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 Pfam PF00842 Alanine racemase, C-terminal domain 232 353 6.0E-37 T 06-07-2017 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 194 221 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 265 280 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 123 135 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 338 351 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 26 42 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 157 168 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 248 263 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 286 303 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 PRINTS PR00992 Alanine racemase signature 61 79 7.1E-62 T 06-07-2017 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS10650 403bd8648349aa09ea28ab38e6bbd597 357 SUPERFAMILY SSF51419 9 233 6.69E-65 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Gene3D G3DSA:3.40.50.300 65 258 1.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Pfam PF16124 RecQ zinc-binding 479 535 4.9E-10 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Pfam PF00270 DEAD/DEAH box helicase 81 241 1.2E-21 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 SMART SM00487 75 273 1.7E-30 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 69 410 1.4E-101 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 SMART SM00490 305 386 9.1E-25 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Gene3D G3DSA:1.10.10.10 482 536 2.0E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 SUPERFAMILY SSF52540 118 405 6.49E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Pfam PF00271 Helicase conserved C-terminal domain 280 385 8.5E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS03900 6b62a297b08e36e3b7cc3b20a34034a6 544 Gene3D G3DSA:3.40.50.300 261 400 2.6E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 Gene3D G3DSA:3.30.1330.30 1 78 2.4E-21 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 Pfam PF00588 SpoU rRNA Methylase family 98 237 5.3E-38 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 SMART SM00967 6 82 9.4E-17 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 SUPERFAMILY SSF75217 70 244 3.53E-48 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 Gene3D G3DSA:3.40.1280.10 93 244 9.2E-52 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 43.151 T 06-07-2017 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 2.8E-15 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 9.3E-69 T 06-07-2017 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 CAL12_RS17590 1881ccc816650230e94e599e0459e6d4 245 SUPERFAMILY SSF55315 3 78 4.36E-17 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAL12_RS18465 ea5a5fa137d934a5438519cdd6ab2aa3 126 Pfam PF01042 Endoribonuclease L-PSP 8 124 3.6E-33 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS18465 ea5a5fa137d934a5438519cdd6ab2aa3 126 Gene3D G3DSA:3.30.1330.40 2 124 2.1E-40 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS18465 ea5a5fa137d934a5438519cdd6ab2aa3 126 SUPERFAMILY SSF55298 1 126 2.51E-41 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS18465 ea5a5fa137d934a5438519cdd6ab2aa3 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 124 2.8E-34 T 06-07-2017 IPR006056 RidA family CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 PIRSF PIRSF000157 1 947 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 944 0.0 T 06-07-2017 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Gene3D G3DSA:3.40.50.970 168 525 6.4E-73 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 803 945 7.2E-51 T 06-07-2017 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Gene3D G3DSA:3.40.50.970 609 807 2.7E-21 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 SUPERFAMILY SSF52518 125 552 2.21E-88 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 SUPERFAMILY SSF52518 584 804 3.73E-48 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Pfam PF02779 Transketolase, pyrimidine binding domain 601 798 1.3E-65 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Pfam PF00676 Dehydrogenase E1 component 221 523 8.0E-49 T 06-07-2017 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 SMART SM00861 601 798 6.9E-60 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS19225 1e4da6ce1899d4215b033fc5fe413275 956 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 47 6.1E-16 T 06-07-2017 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 263 328 9.2E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 SMART SM00382 66 261 1.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 261 336 1.0E-24 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 ProSitePatterns PS00211 ABC transporters family signature. 184 198 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 Gene3D G3DSA:3.40.50.300 29 285 1.4E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 Pfam PF00005 ABC transporter 58 211 2.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24100 240d77dd3ba6269cfce05016369e29bc 356 SUPERFAMILY SSF52540 30 282 3.62E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02385 f47e354a1a0d9a3c667aa050e4dd871d 356 Gene3D G3DSA:3.40.190.10 157 298 1.4E-27 T 06-07-2017 CAL12_RS02385 f47e354a1a0d9a3c667aa050e4dd871d 356 Pfam PF13416 Bacterial extracellular solute-binding protein 61 313 2.1E-26 T 06-07-2017 CAL12_RS02385 f47e354a1a0d9a3c667aa050e4dd871d 356 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 41 5.8E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAL12_RS02385 f47e354a1a0d9a3c667aa050e4dd871d 356 SUPERFAMILY SSF53850 45 354 1.04E-50 T 06-07-2017 CAL12_RS02385 f47e354a1a0d9a3c667aa050e4dd871d 356 Gene3D G3DSA:3.40.190.10 48 156 2.8E-8 T 06-07-2017 CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 Gene3D G3DSA:3.30.200.20 1 103 2.0E-39 T 06-07-2017 CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 Pfam PF01636 Phosphotransferase enzyme family 28 260 1.9E-30 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 Gene3D G3DSA:3.90.1200.10 110 315 3.7E-57 T 06-07-2017 CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 Hamap MF_00301 Homoserine kinase [thrB]. 1 322 151.498 T 06-07-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 2.7E-90 T 06-07-2017 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CAL12_RS09605 d3538f577f7306cef5b8c30f1dc83af7 322 SUPERFAMILY SSF56112 5 314 4.23E-70 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 42 339 4.7E-96 T 06-07-2017 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 6.9E-21 T 06-07-2017 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 SUPERFAMILY SSF55681 93 339 4.98E-72 T 06-07-2017 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 SUPERFAMILY SSF46589 16 100 5.75E-18 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 45.581 T 06-07-2017 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 Gene3D G3DSA:3.30.930.10 10 339 9.3E-121 T 06-07-2017 CAL12_RS09935 d7a32f065332d8f781e48f18acb7c2cb 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 9.6E-92 T 06-07-2017 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CAL12_RS23790 822ac4a7b1013e22df699e8425d87894 144 Gene3D G3DSA:3.40.50.1010 9 139 6.2E-31 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS23790 822ac4a7b1013e22df699e8425d87894 144 SUPERFAMILY SSF88723 8 139 7.01E-34 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS23790 822ac4a7b1013e22df699e8425d87894 144 Pfam PF01850 PIN domain 10 126 9.2E-17 T 06-07-2017 IPR002716 PIN domain CAL12_RS23790 822ac4a7b1013e22df699e8425d87894 144 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 9 136 10.832 T 06-07-2017 IPR022907 VapC family GO:0004540 CAL12_RS24185 f83fe67c0486c9401febe18a61f65d86 278 SUPERFAMILY SSF52096 34 252 3.83E-52 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS24185 f83fe67c0486c9401febe18a61f65d86 278 Pfam PF00378 Enoyl-CoA hydratase/isomerase 46 249 1.2E-38 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS24185 f83fe67c0486c9401febe18a61f65d86 278 Gene3D G3DSA:3.90.226.10 35 258 2.6E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 SUPERFAMILY SSF46626 198 305 6.47E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 PRINTS PR00605 Class IC cytochrome C signature 343 354 3.8E-6 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 PRINTS PR00605 Class IC cytochrome C signature 394 416 3.8E-6 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 335 416 3.0E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 SUPERFAMILY SSF46626 336 429 9.02E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Pfam PF00034 Cytochrome c 51 149 4.9E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Gene3D G3DSA:3.90.10.10 188 205 9.3E-4 T 06-07-2017 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 PIRSF PIRSF000018 17 459 4.2E-161 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Gene3D G3DSA:1.10.760.10 336 439 4.7E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Gene3D G3DSA:1.10.760.10 49 149 4.1E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 Gene3D G3DSA:1.10.760.10 206 301 1.9E-10 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS13705 3154dc18e8b09f6900e64599423ce208 477 SUPERFAMILY SSF46626 41 170 1.47E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 327 6.3E-106 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 8.1E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 Pfam PF00107 Zinc-binding dehydrogenase 152 268 3.1E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 Gene3D G3DSA:3.40.50.720 147 263 1.3E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 SMART SM00829 10 325 3.3E-55 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 SUPERFAMILY SSF51735 112 285 4.53E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 SUPERFAMILY SSF50129 1 146 1.51E-36 T 06-07-2017 IPR011032 GroES-like CAL12_RS04605 7ea6a03f313a07b590058ecbedd76594 329 Gene3D G3DSA:3.90.180.10 1 146 2.9E-46 T 06-07-2017 IPR011032 GroES-like CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Gene3D G3DSA:3.50.50.60 252 404 2.5E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 2.3E-24 T 06-07-2017 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 2.7E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.9E-21 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.9E-21 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 1.9E-21 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Gene3D G3DSA:1.10.1060.10 3 144 5.2E-41 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 SUPERFAMILY SSF51971 142 414 1.18E-65 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 SUPERFAMILY SSF46548 2 154 4.45E-40 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Gene3D G3DSA:3.50.50.60 145 251 3.3E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 SUPERFAMILY SSF51971 398 481 1.77E-11 T 06-07-2017 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 9.6E-232 T 06-07-2017 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CAL12_RS00915 db08437c813930aa02995c2bc472bd41 488 Gene3D G3DSA:3.50.50.60 405 482 1.7E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 SUPERFAMILY SSF48008 73 206 4.97E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 Pfam PF07729 FCD domain 78 200 3.2E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 SMART SM00895 78 201 1.0E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 SUPERFAMILY SSF46785 7 72 4.5E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 SMART SM00345 10 68 2.3E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 Gene3D G3DSA:1.20.120.530 71 206 7.0E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 Gene3D G3DSA:1.10.10.10 7 69 8.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23330 4553ef4bfaa4a484386e37225d68a6ad 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 68 7.3E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21785 f7a10b6e83d1b8fe06ad54502aee5155 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 3.4E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21785 f7a10b6e83d1b8fe06ad54502aee5155 325 Gene3D G3DSA:3.40.190.10 129 231 1.9E-4 T 06-07-2017 CAL12_RS21785 f7a10b6e83d1b8fe06ad54502aee5155 325 PIRSF PIRSF017082 1 325 1.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21785 f7a10b6e83d1b8fe06ad54502aee5155 325 SUPERFAMILY SSF53850 112 286 1.71E-14 T 06-07-2017 CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 SUPERFAMILY SSF52540 475 571 1.28E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 SUPERFAMILY SSF52540 176 408 1.28E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 SMART SM00490 464 561 8.0E-6 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 Hamap MF_00983 Probable primosomal protein N' [priA]. 23 708 23.629 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 SMART SM00487 159 360 1.6E-14 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 Gene3D G3DSA:3.40.50.300 431 605 1.0E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 Pfam PF00270 DEAD/DEAH box helicase 172 331 7.9E-11 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 TIGRFAM TIGR00595 priA: primosomal protein N' 184 706 6.2E-167 T 06-07-2017 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 Gene3D G3DSA:3.40.50.300 161 340 1.7E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25770 11648134c581a5f3868a0b36aefeb2e2 708 Pfam PF00271 Helicase conserved C-terminal domain 465 560 8.5E-5 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.018 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 SUPERFAMILY SSF47060 4 89 3.24E-35 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 4.4E-39 T 06-07-2017 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 Gene3D G3DSA:1.10.287.10 5 89 3.3E-39 T 06-07-2017 IPR009068 S15/NS1, RNA-binding CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 SMART SM01387 8 88 5.9E-53 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 Pfam PF00312 Ribosomal protein S15 8 88 4.5E-38 T 06-07-2017 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS20915 de4e4f7b5a7c0cc54fc5eb71ae288c27 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 2.0E-30 T 06-07-2017 CAL12_RS09050 07283a50b1c52b033f4ed61258ad1159 234 Pfam PF02677 Uncharacterized BCR, COG1636 22 196 5.6E-65 T 06-07-2017 IPR003828 Protein of unknown function DUF208 CAL12_RS27605 59d1631427c9c80f8f8cefb2b3d206b4 475 Gene3D G3DSA:3.40.309.10 262 447 2.3E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS27605 59d1631427c9c80f8f8cefb2b3d206b4 475 Gene3D G3DSA:3.40.605.10 4 261 1.8E-95 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27605 59d1631427c9c80f8f8cefb2b3d206b4 475 Pfam PF00171 Aldehyde dehydrogenase family 17 471 5.4E-159 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27605 59d1631427c9c80f8f8cefb2b3d206b4 475 SUPERFAMILY SSF53720 3 473 2.23E-163 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS17120 c35f4e5541fb08a7b623055b4731c4d4 435 Gene3D G3DSA:1.20.1250.20 20 224 7.7E-46 T 06-07-2017 CAL12_RS17120 c35f4e5541fb08a7b623055b4731c4d4 435 Pfam PF07690 Major Facilitator Superfamily 32 394 6.1E-47 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS17120 c35f4e5541fb08a7b623055b4731c4d4 435 SUPERFAMILY SSF103473 16 428 2.09E-87 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS17120 c35f4e5541fb08a7b623055b4731c4d4 435 Gene3D G3DSA:1.20.1250.20 240 427 5.4E-25 T 06-07-2017 CAL12_RS12340 ef46085c20f9de826cd1e01a9d182711 279 Pfam PF00892 EamA-like transporter family 139 266 1.5E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS12340 ef46085c20f9de826cd1e01a9d182711 279 Pfam PF00892 EamA-like transporter family 1 128 1.3E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS12340 ef46085c20f9de826cd1e01a9d182711 279 SUPERFAMILY SSF103481 173 271 8.11E-18 T 06-07-2017 CAL12_RS12340 ef46085c20f9de826cd1e01a9d182711 279 SUPERFAMILY SSF103481 31 132 1.12E-14 T 06-07-2017 CAL12_RS25115 b5d7acd44f7987097258b5a90354a517 212 Gene3D G3DSA:3.40.50.300 6 202 1.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25115 b5d7acd44f7987097258b5a90354a517 212 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 10 188 1.4E-41 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAL12_RS25115 b5d7acd44f7987097258b5a90354a517 212 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 7 200 25.027 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAL12_RS25115 b5d7acd44f7987097258b5a90354a517 212 SUPERFAMILY SSF52540 7 203 2.89E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25115 b5d7acd44f7987097258b5a90354a517 212 Pfam PF01121 Dephospho-CoA kinase 10 185 1.1E-52 T 06-07-2017 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 SMART SM00829 10 327 3.8E-39 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 SUPERFAMILY SSF51735 118 261 7.32E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 Gene3D G3DSA:3.90.180.10 1 150 3.2E-44 T 06-07-2017 IPR011032 GroES-like CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 Pfam PF00107 Zinc-binding dehydrogenase 157 255 7.1E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 SUPERFAMILY SSF50129 299 324 6.24E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 SUPERFAMILY SSF50129 1 121 6.24E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 Gene3D G3DSA:3.40.50.720 151 257 1.1E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19835 d94cd84106dbb024df8bb62fdac2ab16 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 97 4.8E-13 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.338 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 Gene3D G3DSA:3.40.1060.10 167 281 1.5E-38 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 466 5.6E-237 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 108 116 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 195 208 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 209 222 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 400 413 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 119 132 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 286 300 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 343 354 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 82 95 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 PRINTS PR00415 Aconitase family signature 133 148 1.1E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.3E-156 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 SUPERFAMILY SSF53732 2 465 2.09E-165 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 Gene3D G3DSA:3.30.499.10 335 466 1.6E-62 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 Gene3D G3DSA:3.30.499.10 3 161 4.9E-21 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS09665 880c61021fa1bfcc61dc7d48d8ea09d0 467 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS07765 9ca04b3d448a863cebc94f34c5026f22 166 Pfam PF11162 Protein of unknown function (DUF2946) 11 163 1.6E-10 T 06-07-2017 IPR021333 Protein of unknown function DUF2946 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.7E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 Gene3D G3DSA:3.40.190.10 176 264 4.5E-16 T 06-07-2017 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 Pfam PF03466 LysR substrate binding domain 89 290 1.6E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 SUPERFAMILY SSF46785 3 86 3.69E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 Gene3D G3DSA:3.40.190.10 89 175 9.0E-27 T 06-07-2017 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 SUPERFAMILY SSF53850 89 292 2.02E-34 T 06-07-2017 CAL12_RS10060 78bf81249e47e42fdb115ab9b0aac0d8 310 Gene3D G3DSA:1.10.10.10 1 88 1.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27225 516728b1c4b0fa7d9e643cb7ed50a4fd 466 SUPERFAMILY SSF75304 3 455 3.79E-130 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS27225 516728b1c4b0fa7d9e643cb7ed50a4fd 466 Gene3D G3DSA:3.90.1300.10 3 456 3.1E-133 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS27225 516728b1c4b0fa7d9e643cb7ed50a4fd 466 ProSitePatterns PS00571 Amidases signature. 153 184 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAL12_RS27225 516728b1c4b0fa7d9e643cb7ed50a4fd 466 Pfam PF01425 Amidase 27 447 6.3E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS18820 3b41bc7e440a06ff878b63ee6713558d 294 Gene3D G3DSA:3.20.20.140 11 283 1.5E-80 T 06-07-2017 CAL12_RS18820 3b41bc7e440a06ff878b63ee6713558d 294 Pfam PF04909 Amidohydrolase 12 279 6.2E-37 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS18820 3b41bc7e440a06ff878b63ee6713558d 294 SUPERFAMILY SSF51556 11 279 1.25E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 SUPERFAMILY SSF46785 12 95 5.45E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 Gene3D G3DSA:1.10.10.10 12 95 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 75 2.3E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 7.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 SUPERFAMILY SSF53850 103 301 4.96E-35 T 06-07-2017 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 Pfam PF03466 LysR substrate binding domain 102 301 1.3E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 Gene3D G3DSA:3.40.190.10 186 270 6.4E-17 T 06-07-2017 CAL12_RS06105 6d50c9b62f4b4ba8c48fdd2128a0a384 308 Gene3D G3DSA:3.40.190.10 104 185 5.8E-19 T 06-07-2017 CAL12_RS22370 1406d04865852f1805edf70d6187390f 360 SUPERFAMILY SSF51261 202 341 7.85E-56 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS22370 1406d04865852f1805edf70d6187390f 360 Pfam PF01551 Peptidase family M23 244 337 4.1E-32 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS22370 1406d04865852f1805edf70d6187390f 360 Gene3D G3DSA:2.70.70.10 205 342 1.7E-48 T 06-07-2017 CAL12_RS14490 5112f875b12f075d4bf2cdd487d1408c 137 Gene3D G3DSA:3.30.1330.40 4 136 5.6E-39 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS14490 5112f875b12f075d4bf2cdd487d1408c 137 Pfam PF01042 Endoribonuclease L-PSP 26 134 1.6E-18 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS14490 5112f875b12f075d4bf2cdd487d1408c 137 SUPERFAMILY SSF55298 8 136 7.7E-29 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS14885 77f59760aca4cb3fdf06a4cdcdbb1eb9 241 SUPERFAMILY SSF81452 31 238 2.09E-46 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14885 77f59760aca4cb3fdf06a4cdcdbb1eb9 241 Gene3D G3DSA:1.20.120.80 47 238 1.5E-46 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14885 77f59760aca4cb3fdf06a4cdcdbb1eb9 241 Pfam PF00510 Cytochrome c oxidase subunit III 49 237 8.6E-17 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 Hamap MF_01069 Glucans biosynthesis protein G [mdoG]. 1 504 56.915 T 06-07-2017 IPR023704 Glucan biosynthesis protein G CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 SUPERFAMILY SSF74650 16 389 2.95E-159 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 Gene3D G3DSA:2.60.40.10 393 505 4.0E-37 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 PIRSF PIRSF006281 3 506 8.7E-220 T 06-07-2017 IPR014438 Glucan biosynthesis, periplasmic, MdoG/D CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 SUPERFAMILY SSF81296 393 503 8.26E-30 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 16 501 1.2E-194 T 06-07-2017 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 CAL12_RS26060 8c9c6abb10ddbdf2f7671cceafd34bd5 509 Gene3D G3DSA:2.70.98.10 15 390 1.5E-169 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAL12_RS03810 c7edc3f137c2f9a9f87ff2f95c4627e9 230 SUPERFAMILY SSF52540 3 219 2.56E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03810 c7edc3f137c2f9a9f87ff2f95c4627e9 230 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 230 1.7E-100 T 06-07-2017 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CAL12_RS03810 c7edc3f137c2f9a9f87ff2f95c4627e9 230 Gene3D G3DSA:3.40.50.300 3 227 4.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03810 c7edc3f137c2f9a9f87ff2f95c4627e9 230 SMART SM00382 26 209 4.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03810 c7edc3f137c2f9a9f87ff2f95c4627e9 230 Pfam PF00005 ABC transporter 18 159 2.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03950 00091dfde6d35c5baeae995874a33a70 337 SUPERFAMILY SSF53850 107 297 4.34E-6 T 06-07-2017 CAL12_RS03950 00091dfde6d35c5baeae995874a33a70 337 PIRSF PIRSF017082 1 336 1.5E-50 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03950 00091dfde6d35c5baeae995874a33a70 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 331 6.8E-49 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07850 3bf338fdad601d74490618b0d607a983 260 Pfam PF01925 Sulfite exporter TauE/SafE 25 252 3.6E-25 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Gene3D G3DSA:3.40.190.10 171 268 2.0E-28 T 06-07-2017 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Pfam PF03466 LysR substrate binding domain 94 297 2.2E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 4.8E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 SUPERFAMILY SSF46785 2 82 8.75E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.2E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 SUPERFAMILY SSF53850 88 296 5.25E-42 T 06-07-2017 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Gene3D G3DSA:1.10.10.10 2 82 3.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Gene3D G3DSA:3.40.190.10 88 170 2.9E-26 T 06-07-2017 CAL12_RS01575 21563a1ab6f1c744fa6036e7e108344c 300 Gene3D G3DSA:3.40.190.10 272 299 2.9E-26 T 06-07-2017 CAL12_RS11240 672183d4ba94bc0568f1eb93eef0fa72 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 8.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11240 672183d4ba94bc0568f1eb93eef0fa72 222 SUPERFAMILY SSF161098 12 201 5.76E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11240 672183d4ba94bc0568f1eb93eef0fa72 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 3.0E-30 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS11240 672183d4ba94bc0568f1eb93eef0fa72 222 Gene3D G3DSA:1.10.3720.10 10 216 2.1E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 SUPERFAMILY SSF47413 8 66 6.38E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 Gene3D G3DSA:3.40.50.2300 172 338 7.6E-44 T 06-07-2017 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.3E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 SUPERFAMILY SSF53822 69 338 2.17E-60 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 10 20 7.5E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 7.5E-5 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 SMART SM00354 8 78 5.3E-27 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 Gene3D G3DSA:3.40.50.2300 65 171 9.8E-33 T 06-07-2017 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 Gene3D G3DSA:1.10.260.40 9 64 1.5E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 Pfam PF13377 Periplasmic binding protein-like domain 174 337 1.3E-33 T 06-07-2017 CAL12_RS03505 3e8fdaff58c4729b3a7591632848ca68 363 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 06-07-2017 CAL12_RS26665 34692c9587d78ac922c22e57bdf1a57a 137 Gene3D G3DSA:3.30.565.10 14 132 1.6E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26665 34692c9587d78ac922c22e57bdf1a57a 137 SUPERFAMILY SSF55874 24 132 2.86E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26665 34692c9587d78ac922c22e57bdf1a57a 137 Pfam PF13581 Histidine kinase-like ATPase domain 14 132 4.2E-7 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 ProSitePatterns PS00480 Citrate synthase signature. 270 282 - T 06-07-2017 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 Gene3D G3DSA:1.10.580.10 26 249 9.0E-77 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 Gene3D G3DSA:1.10.230.10 250 334 2.7E-27 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 SUPERFAMILY SSF48256 21 381 5.76E-123 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PIRSF PIRSF001369 14 388 3.4E-112 T 06-07-2017 IPR024176 Citrate synthase, bacterial-type CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 138 151 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 340 354 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 263 283 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 188 203 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 210 238 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 PRINTS PR00143 Citrate synthase signature 320 336 9.9E-36 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 20 387 4.9E-157 T 06-07-2017 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 CAL12_RS19295 d49c2a5826952caef2de0738602e6a5e 388 Pfam PF00285 Citrate synthase, C-terminal domain 21 370 7.8E-113 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS07520 bc53acbc93a8ba1e0bceca2a7e12afa8 406 Gene3D G3DSA:1.25.40.10 23 82 9.9E-5 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS07520 bc53acbc93a8ba1e0bceca2a7e12afa8 406 SUPERFAMILY SSF56059 219 367 2.65E-12 T 06-07-2017 CAL12_RS07520 bc53acbc93a8ba1e0bceca2a7e12afa8 406 Gene3D G3DSA:3.30.1490.20 224 269 1.5E-5 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS09920 1056a466d75ffcc6327e9c09eea81f11 765 Pfam PF04185 Phosphoesterase family 313 478 1.4E-51 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS09920 1056a466d75ffcc6327e9c09eea81f11 765 Pfam PF04185 Phosphoesterase family 46 273 2.0E-54 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS09920 1056a466d75ffcc6327e9c09eea81f11 765 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 760 4.2E-269 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS09920 1056a466d75ffcc6327e9c09eea81f11 765 Pfam PF05506 Domain of unknown function (DUF756) 550 638 2.1E-22 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS09920 1056a466d75ffcc6327e9c09eea81f11 765 Pfam PF05506 Domain of unknown function (DUF756) 650 746 9.8E-20 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS00635 f7371d8118aaa40ed2eba378705720c6 430 Pfam PF13416 Bacterial extracellular solute-binding protein 49 365 2.3E-45 T 06-07-2017 CAL12_RS00635 f7371d8118aaa40ed2eba378705720c6 430 SUPERFAMILY SSF53850 30 422 4.66E-76 T 06-07-2017 CAL12_RS00635 f7371d8118aaa40ed2eba378705720c6 430 Gene3D G3DSA:3.40.190.10 148 357 2.5E-48 T 06-07-2017 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Pfam PF00575 S1 RNA binding domain 670 740 3.7E-22 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:1.10.150.310 519 650 2.4E-46 T 06-07-2017 IPR023097 Tex RuvX-like domain CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SUPERFAMILY SSF47781 580 652 4.0E-19 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SUPERFAMILY SSF158832 18 340 3.27E-110 T 06-07-2017 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SUPERFAMILY SSF50249 658 743 1.12E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:2.40.50.140 653 740 2.9E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SUPERFAMILY SSF53098 341 489 1.27E-50 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:3.30.420.140 345 470 7.7E-50 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:1.10.10.650 17 124 3.1E-44 T 06-07-2017 IPR023319 Tex-like protein, HTH domain CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Pfam PF16921 Tex protein YqgF-like domain 346 471 5.8E-50 T 06-07-2017 IPR032639 Tex protein, YqgF-like domain CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:1.10.3500.10 471 518 7.5E-96 T 06-07-2017 IPR023323 Tex-like domain CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Gene3D G3DSA:1.10.3500.10 125 341 7.5E-96 T 06-07-2017 IPR023323 Tex-like domain CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SMART SM00316 669 740 8.7E-26 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Pfam PF12836 Helix-hairpin-helix motif 511 575 4.6E-26 T 06-07-2017 CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SUPERFAMILY SSF47781 490 576 2.45E-26 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 Pfam PF09371 Tex-like protein N-terminal domain 24 207 7.4E-68 T 06-07-2017 IPR018974 Tex-like protein, N-terminal CAL12_RS19195 0a0982422760439c5dcef93d22b7556d 802 SMART SM00732 345 444 1.6E-36 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 SMART SM00345 15 73 1.1E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 SUPERFAMILY SSF46785 7 102 3.15E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 Gene3D G3DSA:1.10.10.10 4 73 7.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 SUPERFAMILY SSF48008 80 207 2.33E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 Pfam PF07729 FCD domain 84 205 1.0E-27 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 SMART SM00895 83 207 2.1E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 1.5E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25485 9407698e1c9c697b6727c47e7c513494 223 Gene3D G3DSA:1.20.120.530 77 212 7.5E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS26265 f23afde2c02454042b60680cebab0daa 194 Pfam PF14334 Domain of unknown function (DUF4390) 30 182 1.7E-50 T 06-07-2017 IPR025500 Protein of unknown function DUF4390 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Pfam PF02910 Fumarate reductase flavoprotein C-term 449 569 1.5E-21 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 SUPERFAMILY SSF51905 360 437 4.78E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 SUPERFAMILY SSF51905 5 253 4.78E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 SUPERFAMILY SSF56425 236 357 6.88E-31 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Gene3D G3DSA:3.90.700.10 242 352 3.6E-29 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Gene3D G3DSA:3.50.50.60 5 241 3.0E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Gene3D G3DSA:3.50.50.60 353 414 3.0E-77 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 SUPERFAMILY SSF46977 447 571 1.96E-33 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.4E-6 T 06-07-2017 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 1.4E-6 T 06-07-2017 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 PIRSF PIRSF000171 4 561 1.0E-34 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Pfam PF00890 FAD binding domain 13 395 5.8E-70 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07845 e70410c3d87626e930615e3e1a91877c 578 Gene3D G3DSA:1.20.58.100 445 535 2.7E-25 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 Gene3D G3DSA:3.65.10.10 25 243 4.0E-66 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 433 8.0E-115 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 SUPERFAMILY SSF55205 11 437 4.71E-118 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 PIRSF PIRSF000505 7 442 4.8E-132 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 440 32.467 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 Gene3D G3DSA:3.65.10.10 244 436 5.5E-61 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 438 1.1E-133 T 06-07-2017 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAL12_RS18930 cb0f151b8fc315e8a65c16827f50c8ce 444 ProSitePatterns PS00885 EPSP synthase signature 2. 350 368 - T 06-07-2017 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 Gene3D G3DSA:3.20.20.70 3 369 1.7E-111 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 516 534 6.0E-14 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 471 489 6.0E-14 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 601 617 6.0E-14 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 389 408 6.0E-14 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 388 631 3.1E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 Gene3D G3DSA:3.40.50.720 386 474 2.1E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 413 1.4E-6 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 472 486 1.4E-6 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 Gene3D G3DSA:3.50.50.60 475 585 1.5E-19 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 SUPERFAMILY SSF51395 3 364 6.6E-107 T 06-07-2017 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 SUPERFAMILY SSF51905 377 655 8.74E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11615 cd51f67bbf3df2e8e25bf1d162ed1ba8 668 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 329 1.5E-66 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS04635 4ed29e227809833f56adfbe52a0817b4 447 Gene3D G3DSA:1.20.1250.20 233 425 1.3E-21 T 06-07-2017 CAL12_RS04635 4ed29e227809833f56adfbe52a0817b4 447 PIRSF PIRSF002808 2 412 2.2E-33 T 06-07-2017 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CAL12_RS04635 4ed29e227809833f56adfbe52a0817b4 447 SUPERFAMILY SSF103473 8 419 1.96E-84 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS04635 4ed29e227809833f56adfbe52a0817b4 447 Gene3D G3DSA:1.20.1250.20 15 204 5.2E-51 T 06-07-2017 CAL12_RS04635 4ed29e227809833f56adfbe52a0817b4 447 Pfam PF07690 Major Facilitator Superfamily 21 382 6.5E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 SUPERFAMILY SSF53901 215 407 1.97E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 246 1.2E-45 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 SMART SM00825 Beta-ketoacyl synthase 4 407 5.9E-10 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 363 3.7E-29 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 SUPERFAMILY SSF53901 1 251 6.62E-59 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 Gene3D G3DSA:3.40.47.10 262 407 2.1E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10130 eb737cb8f7b9aeef26a2b4dec36c7e03 408 Gene3D G3DSA:3.40.47.10 1 259 1.3E-57 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 Gene3D G3DSA:1.10.760.10 20 52 3.2E-4 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 Gene3D G3DSA:1.10.760.10 146 225 1.5E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 Gene3D G3DSA:1.10.760.10 53 127 2.3E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 PIRSF PIRSF000005 11 226 2.7E-58 T 06-07-2017 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 SUPERFAMILY SSF46626 139 224 1.21E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 Pfam PF00034 Cytochrome c 142 208 8.6E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 Pfam PF00034 Cytochrome c 31 126 3.1E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS27465 d3d26b19b91c864b5e6c345947e5d542 226 SUPERFAMILY SSF46626 10 127 4.95E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS06040 89776942a06887c6b423ae1807fcd71b 479 Pfam PF03972 MmgE/PrpD family 39 460 1.9E-76 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS06040 89776942a06887c6b423ae1807fcd71b 479 Gene3D G3DSA:3.30.1330.120 297 426 5.5E-8 T 06-07-2017 CAL12_RS06040 89776942a06887c6b423ae1807fcd71b 479 SUPERFAMILY SSF103378 46 474 7.19E-72 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 Pfam PF03466 LysR substrate binding domain 87 296 6.4E-50 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 Gene3D G3DSA:1.10.10.10 1 84 2.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 Gene3D G3DSA:3.40.190.10 176 274 1.5E-36 T 06-07-2017 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 Gene3D G3DSA:3.40.190.10 90 175 2.4E-20 T 06-07-2017 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 SUPERFAMILY SSF53850 88 296 9.56E-43 T 06-07-2017 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15235 f6dc3c837df173a2e15b22861c424389 316 SUPERFAMILY SSF46785 1 86 2.21E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 TIGRFAM TIGR01323 nitrile_alph: nitrile hydratase, alpha subunit 13 197 2.7E-86 T 06-07-2017 IPR018141 Nitrile hydratase, alpha subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 SUPERFAMILY SSF56209 9 196 1.26E-77 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 16 196 7.0E-82 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 PIRSF PIRSF001426 1 199 2.5E-89 T 06-07-2017 IPR023900 Nitrile hydratase alpha subunit /Thiocyanate hydrolase gamma subunit KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 Gene3D G3DSA:3.90.330.10 8 197 7.1E-83 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21620 77f79a72e08e81ec552539119c4ea9a9 199 Pfam PF02979 Nitrile hydratase, alpha chain 14 194 4.2E-77 T 06-07-2017 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 Gene3D G3DSA:3.40.50.720 17 117 2.4E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 Gene3D G3DSA:3.40.50.720 118 289 1.2E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 22 317 1.8E-26 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 3.4E-50 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 SUPERFAMILY SSF51735 104 287 3.01E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS17510 7c6fce9ce2444e06df3ef7f822765b59 319 SUPERFAMILY SSF52283 5 136 2.84E-33 T 06-07-2017 CAL12_RS20575 c62cb918b6c8b8f4529ba466e5fe377c 249 Gene3D G3DSA:3.40.50.300 1 245 1.6E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20575 c62cb918b6c8b8f4529ba466e5fe377c 249 SUPERFAMILY SSF52540 1 244 4.8E-35 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20575 c62cb918b6c8b8f4529ba466e5fe377c 249 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 204 6.3E-32 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 Gene3D G3DSA:3.40.190.10 88 188 3.9E-17 T 06-07-2017 CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 SUPERFAMILY SSF46785 1 83 5.45E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 SUPERFAMILY SSF53850 87 305 3.1E-28 T 06-07-2017 CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.2E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 Gene3D G3DSA:3.40.190.10 189 276 1.2E-13 T 06-07-2017 CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 Gene3D G3DSA:1.10.10.10 1 82 4.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14550 8d993c0c1c442d7c2ddff59770973406 317 Pfam PF03466 LysR substrate binding domain 85 301 7.7E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 Pfam PF09339 IclR helix-turn-helix domain 16 60 1.4E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 SUPERFAMILY SSF55781 71 232 1.86E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 Pfam PF01614 Bacterial transcriptional regulator 166 228 1.9E-8 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 SUPERFAMILY SSF46785 14 85 1.54E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 Gene3D G3DSA:3.30.450.40 80 233 1.4E-33 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 SMART SM00346 14 103 1.8E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS10370 b4c503daa93745a8dbcd39c4ab98a2da 255 Gene3D G3DSA:1.10.10.10 3 74 2.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26040 4129ba66b8313df9ef156155bb3f4fc8 100 SUPERFAMILY SSF54292 14 93 4.72E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26040 4129ba66b8313df9ef156155bb3f4fc8 100 Gene3D G3DSA:3.10.20.30 14 96 7.0E-15 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS26040 4129ba66b8313df9ef156155bb3f4fc8 100 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 34 85 1.3E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23060 9375de62d1efe186f42023ebfadc0ef7 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 321 2.9E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23060 9375de62d1efe186f42023ebfadc0ef7 324 PIRSF PIRSF017082 2 324 3.6E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23060 9375de62d1efe186f42023ebfadc0ef7 324 SUPERFAMILY SSF53850 115 286 1.52E-11 T 06-07-2017 CAL12_RS16230 13f183c8556d42568c0c1aa599281a62 324 Gene3D G3DSA:3.40.190.10 128 228 6.1E-5 T 06-07-2017 CAL12_RS16230 13f183c8556d42568c0c1aa599281a62 324 PIRSF PIRSF017082 3 323 5.0E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16230 13f183c8556d42568c0c1aa599281a62 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 4.0E-94 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16230 13f183c8556d42568c0c1aa599281a62 324 SUPERFAMILY SSF53850 111 284 4.07E-18 T 06-07-2017 CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 SUPERFAMILY SSF48179 158 285 2.04E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 Gene3D G3DSA:1.10.1040.10 160 286 2.0E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 157 2.2E-28 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 Gene3D G3DSA:3.40.50.720 1 158 1.3E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 SUPERFAMILY SSF51735 1 158 1.09E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 160 281 8.3E-15 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS10665 c36cfeeda9f4a7e66722c11dfd446cd8 290 PIRSF PIRSF000103 1 289 6.1E-64 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 PIRSF PIRSF002122 3 156 1.1E-58 T 06-07-2017 IPR000235 Ribosomal protein S5/S7 GO:0006412 CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 06-07-2017 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 Gene3D G3DSA:1.10.455.10 7 156 4.7E-64 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.719 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 SUPERFAMILY SSF47973 2 149 1.7E-60 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 7.9E-67 T 06-07-2017 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27675 17ad047b9228bd1ec95485767e07940e 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 6.6E-66 T 06-07-2017 IPR023798 Ribosomal protein S7 domain CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 SMART SM00228 293 375 2.7E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 SUPERFAMILY SSF50494 65 290 1.23E-63 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 Pfam PF13180 PDZ domain 293 383 1.1E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 Pfam PF13365 Trypsin-like peptidase domain 119 254 2.5E-34 T 06-07-2017 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 SUPERFAMILY SSF50156 251 375 3.15E-26 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 Gene3D G3DSA:2.40.10.10 65 172 3.7E-28 T 06-07-2017 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 Gene3D G3DSA:2.40.10.10 181 294 5.4E-45 T 06-07-2017 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 Gene3D G3DSA:2.30.42.10 295 390 4.3E-28 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 148 168 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 333 345 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 190 214 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS00775 93dae0a93dba1920f7aba69dc749decf 392 PRINTS PR00834 HtrA/DegQ protease family signature 127 139 4.7E-54 T 06-07-2017 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 SUPERFAMILY SSF55035 111 219 3.92E-32 T 06-07-2017 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 50 71 1.0E-5 T 06-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 77 97 1.0E-5 T 06-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 313 334 1.0E-5 T 06-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 1.0E-5 T 06-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 17 386 2.9E-112 T 06-07-2017 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 Gene3D G3DSA:3.30.70.420 117 219 5.5E-36 T 06-07-2017 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 Gene3D G3DSA:3.90.770.10 7 116 4.2E-88 T 06-07-2017 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 Gene3D G3DSA:3.90.770.10 234 375 4.2E-88 T 06-07-2017 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 06-07-2017 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 386 5.1E-132 T 06-07-2017 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 SUPERFAMILY SSF56542 229 427 5.89E-103 T 06-07-2017 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 SUPERFAMILY SSF56542 6 119 5.89E-103 T 06-07-2017 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 325 332 - T 06-07-2017 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS03565 1c03b4bc9bd3dd2cc4452b589550fd30 432 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 371 384 - T 06-07-2017 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 SMART SM00829 10 321 2.1E-11 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 Pfam PF00107 Zinc-binding dehydrogenase 154 263 2.8E-15 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 Gene3D G3DSA:3.90.180.10 1 145 4.1E-33 T 06-07-2017 IPR011032 GroES-like CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 SUPERFAMILY SSF50129 1 141 6.09E-32 T 06-07-2017 IPR011032 GroES-like CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 Gene3D G3DSA:3.40.50.720 146 250 4.0E-19 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25225 ebd5712a4a2f1557daa1dc3f79df3683 324 SUPERFAMILY SSF51735 113 264 1.42E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 Pfam PF00534 Glycosyl transferases group 1 496 636 2.3E-22 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 Gene3D G3DSA:3.40.50.2000 464 638 1.4E-13 T 06-07-2017 CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 Pfam PF13439 Glycosyltransferase Family 4 352 471 1.8E-8 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 Gene3D G3DSA:1.25.40.10 25 178 5.7E-4 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 SUPERFAMILY SSF53756 250 306 6.8E-51 T 06-07-2017 CAL12_RS21950 ae769a9f358a912146d9fb51a2f4afc7 695 SUPERFAMILY SSF53756 356 671 6.8E-51 T 06-07-2017 CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 Gene3D G3DSA:1.10.10.10 5 87 2.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 1.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 Pfam PF03466 LysR substrate binding domain 95 294 9.1E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 Gene3D G3DSA:3.40.190.10 95 179 1.3E-18 T 06-07-2017 CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 SUPERFAMILY SSF46785 4 113 1.36E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 SUPERFAMILY SSF53850 95 295 1.05E-39 T 06-07-2017 CAL12_RS14520 870695ea38725938aef19d508bf75d10 296 Gene3D G3DSA:3.40.190.10 180 265 5.9E-18 T 06-07-2017 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 PRINTS PR00050 Cold shock protein signature 39 57 4.1E-9 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 PRINTS PR00050 Cold shock protein signature 3 18 4.1E-9 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 PRINTS PR00050 Cold shock protein signature 24 33 4.1E-9 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 14 33 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 SUPERFAMILY SSF50249 4 65 4.65E-19 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 SMART SM00357 2 66 1.1E-17 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 PIRSF PIRSF002599 1 66 2.2E-16 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 Pfam PF00313 'Cold-shock' DNA-binding domain 2 65 2.2E-22 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20440 81773cb6778d961f62000ee81eadf35f 66 Gene3D G3DSA:2.40.50.140 2 65 2.6E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS22265 100e925e2cf012b88645300be8331b88 218 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 56 199 4.8E-38 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS22265 100e925e2cf012b88645300be8331b88 218 SUPERFAMILY SSF159594 51 205 2.38E-28 T 06-07-2017 CAL12_RS22265 100e925e2cf012b88645300be8331b88 218 Gene3D G3DSA:3.40.50.10610 17 205 1.9E-22 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 SMART SM00382 32 218 2.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 Pfam PF00005 ABC transporter 23 170 8.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 SUPERFAMILY SSF52540 7 240 2.54E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 Gene3D G3DSA:3.40.50.300 6 241 4.9E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21140 72fbb0dd6bf074a13d9fb8fcb3421a84 247 PIRSF PIRSF039085 4 246 1.1E-106 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS08965 40d27a7e190bafba946b65128c531b50 467 TIGRFAM TIGR02400 trehalose_OtsA: alpha,alpha-trehalose-phosphate synthase (UDP-forming) 3 457 1.4E-176 T 06-07-2017 IPR012766 Alpha,alpha-trehalose-phosphate synthase GO:0003825|GO:0005992 KEGG: 00500+2.4.1.15 CAL12_RS08965 40d27a7e190bafba946b65128c531b50 467 Pfam PF00982 Glycosyltransferase family 20 18 457 3.5E-134 T 06-07-2017 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CAL12_RS08965 40d27a7e190bafba946b65128c531b50 467 Gene3D G3DSA:3.40.50.2000 245 441 7.7E-74 T 06-07-2017 CAL12_RS08965 40d27a7e190bafba946b65128c531b50 467 Gene3D G3DSA:3.40.50.2000 1 244 1.1E-71 T 06-07-2017 CAL12_RS08965 40d27a7e190bafba946b65128c531b50 467 SUPERFAMILY SSF53756 2 458 8.16E-146 T 06-07-2017 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 724 7.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 687 705 7.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 PRINTS PR00344 Bacterial sensor protein C-terminal signature 656 670 7.0E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Pfam PF07696 7TMR-DISM extracellular 2 67 201 8.3E-17 T 06-07-2017 IPR011622 7TM-DISM receptor, extracellular domain, type 2 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 SUPERFAMILY SSF47384 505 566 1.75E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 SMART SM00387 615 727 2.1E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 SUPERFAMILY SSF55874 558 723 6.29E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 616 724 8.1E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Gene3D G3DSA:1.10.287.130 506 563 1.5E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Pfam PF00512 His Kinase A (phospho-acceptor) domain 509 566 2.8E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 SMART SM00388 504 568 2.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Pfam PF07695 7TM diverse intracellular signalling 217 369 3.5E-7 T 06-07-2017 IPR011623 7TM-DISM receptor, extracellular domain, type 1 CAL12_RS24350 9aacf7434dcc7cf9ee4c21ef30fa98b5 816 Gene3D G3DSA:3.30.565.10 572 725 1.5E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 505 32.811 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.90.190.20 345 499 4.8E-51 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF53244 341 505 4.27E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.40.1190.10 577 799 4.3E-65 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 515 932 1.2E-128 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF08245 Mur ligase middle domain 120 320 1.6E-49 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF08245 Mur ligase middle domain 592 782 5.7E-40 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF63418 32 109 8.89E-17 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.90.190.20 802 933 6.8E-42 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 438 1.3E-17 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF02875 Mur ligase family, glutamate ligase domain 802 883 9.6E-15 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF53623 111 336 1.57E-72 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 493 933 31.974 T 06-07-2017 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF63418 510 584 2.09E-20 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 32 505 5.2E-143 T 06-07-2017 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF53244 802 932 7.33E-35 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.40.1390.10 510 576 3.1E-20 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.40.1390.10 32 109 1.2E-19 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF01225 Mur ligase family, catalytic domain 34 108 7.4E-10 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Pfam PF01225 Mur ligase family, catalytic domain 510 557 6.6E-9 T 06-07-2017 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 SUPERFAMILY SSF53623 587 799 2.49E-50 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS22430 7c88428ec5be09adec846887987c926c 949 Gene3D G3DSA:3.40.1190.10 111 344 2.9E-83 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 3.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 3.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 3.2E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 SUPERFAMILY SSF53850 103 310 1.71E-27 T 06-07-2017 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 9.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 Gene3D G3DSA:1.10.10.10 5 92 5.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 SUPERFAMILY SSF46785 7 91 2.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 Gene3D G3DSA:3.40.190.10 190 273 2.4E-15 T 06-07-2017 CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 Pfam PF03466 LysR substrate binding domain 101 308 3.0E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04300 22e2c9b6d7dc9a22f80d270335389afc 315 Gene3D G3DSA:3.40.190.10 103 189 7.9E-21 T 06-07-2017 CAL12_RS27720 1cdb21f1f73d1064a525aae68d97640f 309 Gene3D G3DSA:3.40.190.10 112 210 8.9E-5 T 06-07-2017 CAL12_RS27720 1cdb21f1f73d1064a525aae68d97640f 309 PIRSF PIRSF017082 3 309 2.1E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27720 1cdb21f1f73d1064a525aae68d97640f 309 SUPERFAMILY SSF53850 96 270 1.54E-16 T 06-07-2017 CAL12_RS27720 1cdb21f1f73d1064a525aae68d97640f 309 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 33 305 1.0E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23520 8cdd9ae68408b789c7a6dc9e8ec4294f 349 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 85 343 1.6E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23520 8cdd9ae68408b789c7a6dc9e8ec4294f 349 PIRSF PIRSF017082 21 347 8.1E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23520 8cdd9ae68408b789c7a6dc9e8ec4294f 349 SUPERFAMILY SSF53850 134 309 1.71E-11 T 06-07-2017 CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Gene3D G3DSA:3.40.190.10 277 303 7.0E-24 T 06-07-2017 CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Gene3D G3DSA:3.40.190.10 93 176 7.0E-24 T 06-07-2017 CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.0E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 SUPERFAMILY SSF46785 7 88 1.5E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Gene3D G3DSA:1.10.10.10 5 88 4.0E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Gene3D G3DSA:3.40.190.10 177 273 2.8E-22 T 06-07-2017 CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 Pfam PF03466 LysR substrate binding domain 99 296 6.0E-18 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16115 06a79b46e2d0704b6d74954f4b4f6304 306 SUPERFAMILY SSF53850 93 299 4.89E-38 T 06-07-2017 CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 PIRSF PIRSF004682 1 180 9.6E-54 T 06-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 SUPERFAMILY SSF56784 2 176 9.45E-47 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 Gene3D G3DSA:3.40.50.1000 2 175 4.1E-54 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 145 4.8E-45 T 06-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 146 1.2E-32 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CAL12_RS06345 5661167f7132f2398ab2b2538abc565e 181 Pfam PF13242 HAD-hyrolase-like 99 169 1.2E-10 T 06-07-2017 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 SUPERFAMILY SSF50331 236 353 4.13E-20 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Pfam PF00005 ABC transporter 20 161 1.4E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Gene3D G3DSA:2.40.50.100 343 356 3.6E-4 T 06-07-2017 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Gene3D G3DSA:2.40.50.100 265 275 3.6E-4 T 06-07-2017 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Gene3D G3DSA:3.40.50.300 3 234 3.5E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 SUPERFAMILY SSF52540 4 243 2.4E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Gene3D G3DSA:2.40.50.140 276 341 8.7E-14 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 Pfam PF08402 TOBE domain 271 349 3.4E-14 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS00630 f959e5f58b64b198c014830d00509d77 358 SMART SM00382 28 211 6.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 311 7.2E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 SUPERFAMILY SSF52540 353 586 2.61E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 Pfam PF00005 ABC transporter 370 523 1.3E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 SMART SM00382 379 572 5.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07790 89e8fc500b916e0533c5651969977f84 602 Gene3D G3DSA:3.40.50.300 353 591 1.2E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 Gene3D G3DSA:1.10.10.640 181 211 1.4E-31 T 06-07-2017 IPR023094 Toluene tolerance protein, alpha-helical CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 Gene3D G3DSA:1.10.10.640 83 123 1.4E-31 T 06-07-2017 IPR023094 Toluene tolerance protein, alpha-helical CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 Pfam PF05494 MlaC protein 44 207 2.5E-55 T 06-07-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 Gene3D G3DSA:3.10.450.50 38 82 1.4E-28 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 Gene3D G3DSA:3.10.450.50 127 180 1.4E-28 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS00870 7c7df25c0ed02be80f5ac1af5a2efd2d 211 PIRSF PIRSF004649 8 211 1.5E-50 T 06-07-2017 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC CAL12_RS23810 b114ef2dbb7cca86ffee868d698b44d8 339 Gene3D G3DSA:3.20.20.140 287 337 3.4E-80 T 06-07-2017 CAL12_RS23810 b114ef2dbb7cca86ffee868d698b44d8 339 Gene3D G3DSA:3.20.20.140 22 254 3.4E-80 T 06-07-2017 CAL12_RS23810 b114ef2dbb7cca86ffee868d698b44d8 339 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 25 333 1.6E-74 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CAL12_RS23810 b114ef2dbb7cca86ffee868d698b44d8 339 SUPERFAMILY SSF51556 5 254 1.13E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23810 b114ef2dbb7cca86ffee868d698b44d8 339 SUPERFAMILY SSF51556 287 337 1.13E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 SUPERFAMILY SSF103473 8 433 8.5E-83 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 315 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 Gene3D G3DSA:1.20.1250.20 16 202 3.4E-31 T 06-07-2017 CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 Gene3D G3DSA:1.20.1250.20 243 432 3.1E-21 T 06-07-2017 CAL12_RS03855 bf63f3fca663dcda4d549287fbba4a56 438 Pfam PF00083 Sugar (and other) transporter 21 435 6.3E-64 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS24045 1cb140ae19836f5111a99ad42f267dc6 632 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 221 626 6.5E-86 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS24045 1cb140ae19836f5111a99ad42f267dc6 632 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 214 621 2.2E-88 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS24045 1cb140ae19836f5111a99ad42f267dc6 632 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 47 171 1.9E-26 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 SUPERFAMILY SSF56003 13 197 6.28E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 15 130 5.0E-22 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 569 650 1.5E-15 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 273 423 1.1E-16 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 468 567 2.3E-5 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 PIRSF PIRSF036389 2 704 8.5E-182 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 SMART SM01008 172 252 7.5E-8 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Gene3D G3DSA:3.30.365.10 347 529 2.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Gene3D G3DSA:3.90.1170.50 148 224 8.5E-15 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Gene3D G3DSA:3.30.365.10 530 707 1.2E-42 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 Gene3D G3DSA:3.30.365.10 14 137 2.7E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21410 c6a39d46483ffa1a43830ad259cc2847 709 SUPERFAMILY SSF56003 272 706 2.56E-110 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 354 614 3.0E-46 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 SUPERFAMILY SSF53474 10 371 7.75E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 Gene3D G3DSA:3.40.50.1820 241 365 9.5E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 Gene3D G3DSA:3.40.50.1820 11 167 9.5E-74 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 Gene3D G3DSA:2.60.120.260 377 618 3.6E-77 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 16 618 8.5E-111 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 SUPERFAMILY SSF49785 379 619 2.55E-57 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 SMART SM00939 334 615 8.0E-73 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS24535 3221948d2ac2a736044827c8d8ae80f9 631 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 20 303 6.8E-56 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAL12_RS01060 3ddb09212b18a6bf44c2d9d508f1c0a2 434 SUPERFAMILY SSF103473 1 178 2.09E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01060 3ddb09212b18a6bf44c2d9d508f1c0a2 434 SUPERFAMILY SSF103473 225 420 2.09E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01060 3ddb09212b18a6bf44c2d9d508f1c0a2 434 Gene3D G3DSA:1.20.1250.20 247 419 3.1E-18 T 06-07-2017 CAL12_RS01060 3ddb09212b18a6bf44c2d9d508f1c0a2 434 Gene3D G3DSA:1.20.1250.20 1 175 7.7E-25 T 06-07-2017 CAL12_RS01060 3ddb09212b18a6bf44c2d9d508f1c0a2 434 Pfam PF07690 Major Facilitator Superfamily 2 386 1.7E-51 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS18660 d7c11838730962f49975ca9f0b3b1dc4 558 Pfam PF00171 Aldehyde dehydrogenase family 94 507 8.9E-38 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS18660 d7c11838730962f49975ca9f0b3b1dc4 558 SUPERFAMILY SSF53720 78 532 6.68E-62 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS18660 d7c11838730962f49975ca9f0b3b1dc4 558 Gene3D G3DSA:3.40.605.10 94 306 3.2E-31 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS18660 d7c11838730962f49975ca9f0b3b1dc4 558 Gene3D G3DSA:3.40.309.10 315 518 3.0E-31 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS18660 d7c11838730962f49975ca9f0b3b1dc4 558 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 7 558 1.0E-274 T 06-07-2017 IPR011975 Phenylacetic acid degradation protein PaaN2 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 67 177 4.5E-20 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.90.1170.50 47 166 9.2E-33 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 167 213 2.4E-12 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 320 344 2.4E-12 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 477 627 1.4E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 SUPERFAMILY SSF56003 171 797 2.22E-153 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 SMART SM01008 67 179 4.0E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 199 741 3.6E-115 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 214 317 2.3E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 SUPERFAMILY SSF54665 46 177 6.8E-34 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 657 797 3.0E-51 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS20675 180835838f798727b2a7838c1c059038 798 Gene3D G3DSA:3.30.365.10 393 476 3.0E-51 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 PIRSF PIRSF000103 1 288 1.2E-59 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 159 279 1.0E-24 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 SUPERFAMILY SSF48179 158 283 1.09E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 153 8.5E-28 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 SUPERFAMILY SSF51735 1 161 5.58E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 Gene3D G3DSA:3.40.50.720 1 156 5.7E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06970 2d1fcd9657fdded2145903deb8c504ca 288 Gene3D G3DSA:1.10.1040.10 159 285 8.3E-34 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Gene3D G3DSA:3.30.70.270 114 281 1.2E-51 T 06-07-2017 CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Pfam PF08448 PAS fold 2 102 1.8E-9 T 06-07-2017 IPR013656 PAS fold-4 CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Pfam PF00563 EAL domain 293 527 6.3E-68 T 06-07-2017 IPR001633 EAL domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Gene3D G3DSA:3.30.450.20 1 99 3.1E-18 T 06-07-2017 CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 108 273 6.3E-35 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Pfam PF00990 Diguanylate cyclase, GGDEF domain 112 269 1.1E-40 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 SUPERFAMILY SSF55785 2 89 2.44E-11 T 06-07-2017 IPR000014 PAS domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 SUPERFAMILY SSF141868 293 539 3.92E-80 T 06-07-2017 IPR001633 EAL domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 SMART SM00052 286 532 2.9E-87 T 06-07-2017 IPR001633 EAL domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 SUPERFAMILY SSF55073 117 277 1.1E-42 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 SMART SM00267 101 276 7.3E-49 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS13885 1879845eddf08ffc7a8551e358c98235 546 Gene3D G3DSA:3.20.20.450 290 539 6.2E-89 T 06-07-2017 IPR001633 EAL domain CAL12_RS07275 643080efbe9f79b0ecc7121872650de5 674 Pfam PF01590 GAF domain 98 239 7.9E-11 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS07275 643080efbe9f79b0ecc7121872650de5 674 Gene3D G3DSA:3.30.450.40 77 253 5.3E-25 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07275 643080efbe9f79b0ecc7121872650de5 674 SMART SM00065 98 249 2.8E-15 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS07275 643080efbe9f79b0ecc7121872650de5 674 SUPERFAMILY SSF55781 86 265 1.09E-26 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07275 643080efbe9f79b0ecc7121872650de5 674 Pfam PF13556 PucR C-terminal helix-turn-helix domain 602 659 3.9E-14 T 06-07-2017 IPR025736 PucR C-terminal helix-turn-helix domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00668 Condensation domain 1574 1898 2.0E-55 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00668 Condensation domain 51 347 1.7E-58 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00668 Condensation domain 1117 1416 1.8E-52 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF47336 1014 1084 6.67E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.40.50.980 2217 2367 1.6E-38 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 1756 1785 1.07E-47 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 1814 2031 1.07E-47 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 1302 1543 6.34E-39 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.40.50.980 518 684 2.2E-47 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.40.50.980 2060 2216 2.1E-38 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF56801 2023 2599 6.41E-144 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2610 2625 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SMART SM00823 Phosphopantetheine attachment site 1022 1090 0.035 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SMART SM00823 Phosphopantetheine attachment site 2586 2655 1.2E-9 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 1118 1294 1.33E-38 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 1580 1755 9.45E-41 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.40.50.980 685 830 7.2E-45 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:1.10.1200.10 1025 1091 2.6E-23 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:1.10.1200.10 2590 2655 8.8E-29 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF13193 AMP-binding enzyme C-terminal domain 927 997 1.6E-8 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF13193 AMP-binding enzyme C-terminal domain 2477 2560 7.0E-7 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF47336 2578 2652 3.27E-21 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1423 1565 2.1E-32 T 06-07-2017 IPR010060 Non-ribosomal peptide synthase CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 ProSitePatterns PS00455 Putative AMP-binding domain signature. 663 674 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF13745 HxxPF-repeated domain 369 470 2.3E-17 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF56801 481 1034 1.57E-154 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 51 228 2.0E-43 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.30.300.30 2464 2589 8.5E-37 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:3.30.300.30 914 1024 6.6E-36 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1046 1061 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00501 AMP-binding enzyme 2063 2468 3.3E-84 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00501 AMP-binding enzyme 523 919 1.5E-94 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00550 Phosphopantetheine attachment site 2589 2651 6.0E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Pfam PF00550 Phosphopantetheine attachment site 1025 1085 1.7E-8 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2084 2493 1.1E-119 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 544 943 2.2E-132 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2208 2219 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:2.30.38.10 2378 2459 1.4E-23 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 Gene3D G3DSA:2.30.38.10 831 908 4.8E-25 T 06-07-2017 CAL12_RS11050 bec5ed5301e124c5f7b7a315fd513c1e 2678 SUPERFAMILY SSF52777 235 492 1.56E-46 T 06-07-2017 CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 Gene3D G3DSA:3.40.50.300 7 229 4.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 7 228 2.5E-95 T 06-07-2017 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 SMART SM00382 39 232 2.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 SUPERFAMILY SSF52540 8 229 2.97E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05165 cce07fd2ca27d52f96ca8aa18eab0940 237 Pfam PF00005 ABC transporter 30 184 2.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Pfam PF00889 Elongation factor TS 73 271 1.2E-67 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Gene3D G3DSA:1.10.8.10 2 55 8.9E-22 T 06-07-2017 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 288 76.801 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 SUPERFAMILY SSF54713 56 147 6.21E-23 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 SUPERFAMILY SSF46934 3 56 5.41E-14 T 06-07-2017 IPR009060 UBA-like GO:0005515 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 2.3E-90 T 06-07-2017 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Gene3D G3DSA:1.10.286.20 191 234 5.7E-18 T 06-07-2017 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 06-07-2017 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Gene3D G3DSA:3.30.479.20 152 186 1.1E-25 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Gene3D G3DSA:3.30.479.20 235 270 1.1E-25 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 SUPERFAMILY SSF54713 152 288 3.01E-46 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS12120 f6966ba3fd9354d1d1e86e89968b9382 292 Gene3D G3DSA:3.30.479.20 57 150 6.7E-21 T 06-07-2017 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS06325 dd6841a08d633ed073855c2eb6987849 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 130 2.1E-67 T 06-07-2017 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAL12_RS06325 dd6841a08d633ed073855c2eb6987849 131 SUPERFAMILY SSF54593 1 127 2.42E-38 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS06325 dd6841a08d633ed073855c2eb6987849 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 3.1E-25 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS06325 dd6841a08d633ed073855c2eb6987849 131 Gene3D G3DSA:3.10.180.10 1 128 1.3E-49 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS06325 dd6841a08d633ed073855c2eb6987849 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 06-07-2017 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CAL12_RS23630 63c6bbcb35ca48683872adf993bdb064 40 Gene3D G3DSA:2.160.20.20 4 40 1.0E-6 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23630 63c6bbcb35ca48683872adf993bdb064 40 Pfam PF12951 Passenger-associated-transport-repeat 13 40 2.4E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23630 63c6bbcb35ca48683872adf993bdb064 40 SUPERFAMILY SSF51126 4 40 7.22E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23630 63c6bbcb35ca48683872adf993bdb064 40 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 12 40 4.0E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 SUPERFAMILY SSF52540 5 227 1.39E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 Pfam PF00005 ABC transporter 24 166 2.7E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 Gene3D G3DSA:3.40.50.300 4 226 1.7E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 1.3E-101 T 06-07-2017 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07035 f3ae1a9a986b55325e6c736c1499bcb1 293 SMART SM00382 33 216 1.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 70 2.2E-26 T 06-07-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Gene3D G3DSA:2.160.10.10 91 255 7.7E-59 T 06-07-2017 CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 272 1.0E-141 T 06-07-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 167 3.2E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Gene3D G3DSA:1.10.166.10 4 71 4.0E-30 T 06-07-2017 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 176 210 4.8E-13 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 SUPERFAMILY SSF51161 3 257 9.01E-75 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS17245 e1d2b12b6e62ed2d6bc9bf26410672d6 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 273 56.138 T 06-07-2017 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 CAL12_RS03000 40d97a682dc7b44fd01d029f441eed9e 131 Gene3D G3DSA:1.10.3830.10 11 129 5.8E-41 T 06-07-2017 CAL12_RS03000 40d97a682dc7b44fd01d029f441eed9e 131 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 124 7.3E-34 T 06-07-2017 IPR000829 DAGK family GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 SMART SM00922 150 249 4.3E-16 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 SUPERFAMILY SSF54826 2 132 3.54E-23 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 Gene3D G3DSA:3.30.390.10 2 129 1.3E-32 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 SUPERFAMILY SSF51604 119 383 1.83E-62 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 Pfam PF13378 Enolase C-terminal domain-like 153 376 2.3E-48 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 38 131 2.4E-14 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 199 230 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS13595 d9970d15f477eb86382529a5f2dc73f7 389 Gene3D G3DSA:3.20.20.120 130 383 1.5E-62 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 258 1.5E-41 T 06-07-2017 CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 SUPERFAMILY SSF51735 7 258 5.6E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 Gene3D G3DSA:3.40.50.720 2 258 1.6E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12515 d74178b7ba67a4714cf7fa8ef0b19b0a 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.4E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01055 06d893060508842930f17b37c20932c0 456 SUPERFAMILY SSF53448 2 250 3.22E-60 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Gene3D G3DSA:2.160.10.10 323 454 2.2E-31 T 06-07-2017 CAL12_RS01055 06d893060508842930f17b37c20932c0 456 SUPERFAMILY SSF51161 255 437 4.88E-48 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Pfam PF12804 MobA-like NTP transferase domain 4 128 1.8E-23 T 06-07-2017 IPR025877 MobA-like NTP transferase CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Gene3D G3DSA:2.160.10.10 245 322 2.9E-17 T 06-07-2017 CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 8.9E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 395 429 8.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 267 299 1.0E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS01055 06d893060508842930f17b37c20932c0 456 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 455 5.6E-189 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Gene3D G3DSA:3.90.550.10 1 244 3.5E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS01055 06d893060508842930f17b37c20932c0 456 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 452 42.731 T 06-07-2017 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CAL12_RS26925 0aa2d906fcdb72e86881c5988fd9e4be 835 Pfam PF05045 Rhamnan synthesis protein F 597 822 2.0E-47 T 06-07-2017 IPR007739 Rhamnan synthesis F CAL12_RS26925 0aa2d906fcdb72e86881c5988fd9e4be 835 SUPERFAMILY SSF53756 110 484 7.85E-32 T 06-07-2017 CAL12_RS26925 0aa2d906fcdb72e86881c5988fd9e4be 835 Gene3D G3DSA:3.40.50.2000 291 446 8.0E-12 T 06-07-2017 CAL12_RS26925 0aa2d906fcdb72e86881c5988fd9e4be 835 Pfam PF00534 Glycosyl transferases group 1 298 460 2.4E-13 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 Gene3D G3DSA:3.40.50.300 315 527 4.4E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 Gene3D G3DSA:3.40.50.300 1 270 6.5E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 SMART SM00382 26 228 3.6E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 SMART SM00382 348 515 2.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 Pfam PF12848 ABC transporter 221 303 5.3E-24 T 06-07-2017 IPR032781 ABC-transporter extension domain CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 SUPERFAMILY SSF52540 303 522 2.55E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 SUPERFAMILY SSF52540 123 255 2.35E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 SUPERFAMILY SSF52540 2 92 2.35E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 Pfam PF00005 ABC transporter 340 470 4.8E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13875 9aa6ae237c17daf9b8757ccf12e3a224 544 Pfam PF00005 ABC transporter 17 182 1.3E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09575 a92d2bdebfa4295376a3149b7d2c6fed 312 SMART SM00858 46 110 0.0047 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS09575 a92d2bdebfa4295376a3149b7d2c6fed 312 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 10 258 2.5E-44 T 06-07-2017 IPR017592 Pilus assembly, Flp-type CpaB CAL12_RS09575 a92d2bdebfa4295376a3149b7d2c6fed 312 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 117 217 2.3E-20 T 06-07-2017 IPR031571 Flp pilus assembly protein RcpC/CpaB domain CAL12_RS26150 d4fc679149677b4265a2813f550e28ca 251 SUPERFAMILY SSF53639 14 227 5.49E-50 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS26150 d4fc679149677b4265a2813f550e28ca 251 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 199 1.2E-35 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS26150 d4fc679149677b4265a2813f550e28ca 251 SMART SM01007 19 200 1.3E-34 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS26150 d4fc679149677b4265a2813f550e28ca 251 Gene3D G3DSA:3.40.225.10 16 228 3.8E-47 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS13910 8179287ce7e589cfa0b77a035244e93a 507 SUPERFAMILY SSF75304 7 464 5.36E-125 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS13910 8179287ce7e589cfa0b77a035244e93a 507 Pfam PF01425 Amidase 28 452 7.4E-94 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS13910 8179287ce7e589cfa0b77a035244e93a 507 Gene3D G3DSA:3.90.1300.10 5 463 6.7E-120 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS09220 e57945e5d9b845aec7597e8933ec92da 428 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 23 417 28.474 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAL12_RS09220 e57945e5d9b845aec7597e8933ec92da 428 Pfam PF04551 GcpE protein 35 415 7.0E-114 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAL12_RS09220 e57945e5d9b845aec7597e8933ec92da 428 SUPERFAMILY SSF56014 314 422 1.53E-8 T 06-07-2017 CAL12_RS09220 e57945e5d9b845aec7597e8933ec92da 428 PIRSF PIRSF004640 15 425 3.6E-129 T 06-07-2017 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAL12_RS09220 e57945e5d9b845aec7597e8933ec92da 428 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 23 414 5.6E-118 T 06-07-2017 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.8E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 SUPERFAMILY SSF51735 8 254 3.08E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 4.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 193 0.0098 T 06-07-2017 CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 Pfam PF00106 short chain dehydrogenase 11 196 1.0E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 Gene3D G3DSA:3.40.50.720 11 228 6.4E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 PIRSF PIRSF000126 1 268 5.1E-71 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16875 22d0c90bc66f8bc6f955028349b34934 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS09610 0fed941bad97fffb96281401faf6f26e 334 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 89 107 - T 06-07-2017 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAL12_RS09610 0fed941bad97fffb96281401faf6f26e 334 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 2 322 46.019 T 06-07-2017 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 CAL12_RS09610 0fed941bad97fffb96281401faf6f26e 334 SUPERFAMILY SSF51395 7 303 2.56E-66 T 06-07-2017 CAL12_RS09610 0fed941bad97fffb96281401faf6f26e 334 Pfam PF01207 Dihydrouridine synthase (Dus) 10 308 1.7E-74 T 06-07-2017 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CAL12_RS09610 0fed941bad97fffb96281401faf6f26e 334 Gene3D G3DSA:3.20.20.70 7 247 3.9E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 762 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 Gene3D G3DSA:3.20.20.210 397 761 2.8E-129 T 06-07-2017 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 435 757 5.6E-157 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 SUPERFAMILY SSF51726 5 399 7.59E-108 T 06-07-2017 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 Gene3D G3DSA:3.20.20.210 3 395 1.0E-147 T 06-07-2017 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 317 1.3E-116 T 06-07-2017 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 PIRSF PIRSF000382 1 763 0.0 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 762 37.439 T 06-07-2017 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS09490 28ff8d4455c4773780fb9fba983877a9 763 SUPERFAMILY SSF51726 413 762 1.96E-117 T 06-07-2017 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 Gene3D G3DSA:1.10.150.120 99 179 4.4E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 Gene3D G3DSA:3.10.20.30 25 98 2.7E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 SUPERFAMILY SSF47741 108 176 4.71E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 31 83 1.3E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 SUPERFAMILY SSF54292 28 111 3.8E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 63 71 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS15645 5c3a3d124c8992c8b43245bdb2d00bfb 181 Pfam PF01799 [2Fe-2S] binding domain 97 169 1.4E-27 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 SUPERFAMILY SSF52540 9 264 2.22E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 330 1.3E-23 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 1.7E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 SMART SM00382 38 243 2.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 Pfam PF00005 ABC transporter 30 193 5.9E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 Gene3D G3DSA:3.40.50.300 8 267 5.6E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21490 c3a44b7e4c90f61239fda3fd1243f99f 335 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 SMART SM00862 155 231 5.5E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 Pfam PF00072 Response regulator receiver domain 7 117 3.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 7.8E-28 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 SUPERFAMILY SSF52172 5 127 1.21E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 Gene3D G3DSA:3.40.50.2300 5 123 7.3E-41 T 06-07-2017 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 SUPERFAMILY SSF46894 128 231 8.5E-31 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 Gene3D G3DSA:1.10.10.10 135 232 2.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07930 e7df0c1fea9e1472ab13fa1a82147399 239 SMART SM00448 5 116 7.1E-42 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 Gene3D G3DSA:3.40.50.620 2 170 4.6E-69 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 Gene3D G3DSA:3.30.1300.10 173 280 4.0E-30 T 06-07-2017 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 4.9E-95 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 278 6.9E-86 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 64 1.9E-7 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 SUPERFAMILY SSF52374 2 280 3.44E-94 T 06-07-2017 CAL12_RS25135 ac116069e653d4d3bbac591cd4c8d1e2 280 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 37.202 T 06-07-2017 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CAL12_RS20700 6194e18de96f2efca87c653ec2c21e8e 398 Gene3D G3DSA:3.20.20.100 70 380 1.8E-48 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS20700 6194e18de96f2efca87c653ec2c21e8e 398 Pfam PF00248 Aldo/keto reductase family 72 380 2.0E-41 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS20700 6194e18de96f2efca87c653ec2c21e8e 398 SUPERFAMILY SSF51430 70 381 9.56E-53 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS02045 2352cddd6ab7832c15be3ef55e63f341 338 Gene3D G3DSA:3.40.190.10 119 245 1.8E-10 T 06-07-2017 CAL12_RS02045 2352cddd6ab7832c15be3ef55e63f341 338 Pfam PF09084 NMT1/THI5 like 43 255 6.1E-53 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS02045 2352cddd6ab7832c15be3ef55e63f341 338 SUPERFAMILY SSF53850 36 319 1.56E-33 T 06-07-2017 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 Pfam PF00171 Aldehyde dehydrogenase family 12 476 5.1E-174 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 Gene3D G3DSA:3.40.605.10 2 262 1.7E-96 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 SUPERFAMILY SSF53720 2 478 6.41E-169 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS13300 3c3ec8ffea63e6b92f1b02db1be2a928 491 Gene3D G3DSA:3.40.309.10 263 441 3.9E-73 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Gene3D G3DSA:3.40.50.980 184 340 3.7E-40 T 06-07-2017 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Gene3D G3DSA:3.40.50.980 3 183 4.2E-38 T 06-07-2017 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 437 512 5.5E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Pfam PF00501 AMP-binding enzyme 9 427 5.4E-98 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 SUPERFAMILY SSF56801 3 524 2.62E-153 T 06-07-2017 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Gene3D G3DSA:2.30.38.10 341 419 2.1E-25 T 06-07-2017 CAL12_RS16275 17c77ae570baea6ae1d276ed37d94de3 530 Gene3D G3DSA:3.30.300.30 425 524 1.7E-33 T 06-07-2017 CAL12_RS24710 f72ab41318c128482bb2c980881cc066 217 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 33 201 3.4E-25 T 06-07-2017 IPR005247 YbhB/YbcL CAL12_RS24710 f72ab41318c128482bb2c980881cc066 217 Gene3D G3DSA:3.90.280.10 1 207 6.1E-60 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS24710 f72ab41318c128482bb2c980881cc066 217 SUPERFAMILY SSF49777 1 205 4.84E-39 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS24710 f72ab41318c128482bb2c980881cc066 217 Pfam PF01161 Phosphatidylethanolamine-binding protein 31 201 4.9E-37 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 SUPERFAMILY SSF100950 2 228 9.94E-89 T 06-07-2017 CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 06-07-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 Gene3D G3DSA:3.40.1080.10 3 216 1.4E-101 T 06-07-2017 CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 Pfam PF01144 Coenzyme A transferase 6 217 2.5E-80 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 SMART SM00882 5 217 7.5E-91 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS08575 da6d74be2ae8fe432bc61786d0c5a731 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 1.8E-80 T 06-07-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 CAL12_RS12720 3553412fc75fbdfc52bb8673e8799c52 150 PIRSF PIRSF004681 1 140 2.8E-49 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAL12_RS12720 3553412fc75fbdfc52bb8673e8799c52 150 SUPERFAMILY SSF111038 4 139 2.35E-46 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAL12_RS12720 3553412fc75fbdfc52bb8673e8799c52 150 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 11 139 3.0E-42 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAL12_RS12720 3553412fc75fbdfc52bb8673e8799c52 150 Gene3D G3DSA:2.60.120.460 3 139 6.6E-54 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAL12_RS12720 3553412fc75fbdfc52bb8673e8799c52 150 Pfam PF01894 Uncharacterised protein family UPF0047 21 136 2.2E-38 T 06-07-2017 IPR001602 Uncharacterised protein family UPF0047 CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 Gene3D G3DSA:1.10.10.10 1 83 3.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 SUPERFAMILY SSF53850 89 296 3.98E-41 T 06-07-2017 CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 SUPERFAMILY SSF46785 3 87 1.78E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 Pfam PF03466 LysR substrate binding domain 88 294 8.4E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 Gene3D G3DSA:3.40.190.10 178 261 7.8E-21 T 06-07-2017 CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.1E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14190 2ede11adc8371ff74173289296a0d648 306 Gene3D G3DSA:3.40.190.10 92 177 5.7E-21 T 06-07-2017 CAL12_RS26485 dd1c40ae56bdccc8dcabf22825accdc0 189 Pfam PF04314 Protein of unknown function (DUF461) 31 140 1.2E-40 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAL12_RS26485 dd1c40ae56bdccc8dcabf22825accdc0 189 SUPERFAMILY SSF110087 6 147 2.48E-47 T 06-07-2017 IPR007410 DR1885-like metal-binding protein CAL12_RS13295 c8f94891933a6b333508d14c62ae9dd9 399 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 349 2.5E-66 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS13295 c8f94891933a6b333508d14c62ae9dd9 399 Gene3D G3DSA:3.20.20.70 4 350 4.0E-104 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS13295 c8f94891933a6b333508d14c62ae9dd9 399 SUPERFAMILY SSF51395 6 351 8.74E-99 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 Gene3D G3DSA:3.50.50.60 111 306 3.9E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 281 4.0E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-23 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 2.4E-23 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.4E-23 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.4E-23 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.4E-23 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 Gene3D G3DSA:3.50.50.60 2 110 8.3E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 SUPERFAMILY SSF51905 143 309 2.33E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 SUPERFAMILY SSF51905 2 191 2.93E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.3E-15 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.3E-15 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 1.3E-15 T 06-07-2017 CAL12_RS07030 d34c47ac6178e5a7b21d33cb9229203c 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.3E-15 T 06-07-2017 CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 Gene3D G3DSA:2.160.20.20 936 1408 4.5E-55 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 Gene3D G3DSA:2.40.128.130 1415 1735 9.4E-65 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1288 1735 2.1E-71 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 Pfam PF13018 Extended Signal Peptide of Type V secretion system 5 24 2.0E-4 T 06-07-2017 IPR024973 ESPR domain CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 Pfam PF03797 Autotransporter beta-domain 1459 1712 5.6E-35 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00869 1459 1722 1.1E-26 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SUPERFAMILY SSF103515 1423 1735 8.89E-39 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SUPERFAMILY SSF51126 933 1397 1.36E-37 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 1318 1355 6200.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 881 905 1000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 105 127 5800.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 534 555 5800.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 1131 1152 210.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 1057 1081 4300.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 454 484 4000.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 927 951 4700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 1032 1056 2500.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 395 428 9700.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS27085 dd8515910a34e5c694dfda3e8a1ad709 1735 SMART SM00710 1159 1181 610.0 T 06-07-2017 IPR006626 Parallel beta-helix repeat CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 Gene3D G3DSA:3.30.70.100 6 92 1.5E-27 T 06-07-2017 CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 PRINTS PR00112 Acylphosphatase signature 8 23 3.1E-7 T 06-07-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 PRINTS PR00112 Acylphosphatase signature 29 54 3.1E-7 T 06-07-2017 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 ProSitePatterns PS00151 Acylphosphatase signature 2. 37 53 - T 06-07-2017 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 Pfam PF00708 Acylphosphatase 8 92 7.0E-24 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS00395 f25937a6e2160a6c63ab6fc061c80733 94 SUPERFAMILY SSF54975 5 92 2.83E-25 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 SUPERFAMILY SSF81442 29 536 7.06E-194 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 Gene3D G3DSA:1.20.210.10 21 536 1.5E-218 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 41 482 2.8E-155 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 260 314 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 79 102 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 106 130 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 178 196 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 258 279 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 32 57 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 349 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 441 462 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 149 161 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 207 226 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 304 319 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 363 381 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 391 410 7.3E-122 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS00995 bdab1eadc5ea1c969ca60ca398bc2906 537 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 33 536 4.6E-216 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 SMART SM01130 8 297 4.7E-103 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 8 295 45.347 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 SUPERFAMILY SSF51569 9 296 9.73E-86 T 06-07-2017 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 139 170 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 4.5E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 4.5E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 4.5E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 109 125 4.5E-20 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 12 292 4.1E-76 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 Gene3D G3DSA:3.20.20.70 8 298 6.4E-91 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 Pfam PF00701 Dihydrodipicolinate synthetase family 9 290 3.3E-69 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21775 3d88790923fd98fea2d2ecec1abf681a 301 PIRSF PIRSF001365 5 301 4.7E-78 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 SMART SM00490 277 358 7.9E-34 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 Gene3D G3DSA:3.40.50.300 231 389 2.9E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 172 180 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 Pfam PF00270 DEAD/DEAH box helicase 41 214 1.9E-51 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 Gene3D G3DSA:3.40.50.300 9 230 4.2E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 Pfam PF00271 Helicase conserved C-terminal domain 253 358 3.2E-28 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 SMART SM00487 36 241 2.3E-64 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS05715 4ad6d8107a2ed57a3174ccbaf77f9287 497 SUPERFAMILY SSF52540 93 379 3.03E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 Gene3D G3DSA:3.40.190.10 191 262 4.9E-7 T 06-07-2017 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 SUPERFAMILY SSF46785 1 110 4.98E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 Gene3D G3DSA:3.40.190.10 89 190 8.4E-22 T 06-07-2017 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 Pfam PF03466 LysR substrate binding domain 90 288 5.8E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 Gene3D G3DSA:1.10.10.10 1 81 5.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.0E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15725 d122048632fa7e7dd1297f8ca90d84be 328 SUPERFAMILY SSF53850 90 293 6.65E-33 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Pfam PF01568 Molydopterin dinucleotide binding domain 631 755 3.3E-24 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 SUPERFAMILY SSF53706 12 633 1.57E-151 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Gene3D G3DSA:3.40.228.10 150 354 3.6E-46 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 457 474 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Gene3D G3DSA:3.90.55.10 459 562 4.8E-29 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 SUPERFAMILY SSF50692 625 779 2.94E-38 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Gene3D G3DSA:2.40.40.20 605 774 8.9E-52 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Pfam PF00384 Molybdopterin oxidoreductase 54 511 5.5E-66 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Gene3D G3DSA:3.40.50.740 47 149 1.3E-37 T 06-07-2017 CAL12_RS22335 79d7c95589cd4054fe4e90c08e76c53f 802 Gene3D G3DSA:3.40.50.740 355 458 1.3E-37 T 06-07-2017 CAL12_RS07185 6aa204645473b2daf8c64c8ad9c5caa9 408 SUPERFAMILY SSF53383 11 406 8.11E-111 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS07185 6aa204645473b2daf8c64c8ad9c5caa9 408 Pfam PF00155 Aminotransferase class I and II 40 400 9.8E-67 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS07185 6aa204645473b2daf8c64c8ad9c5caa9 408 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 244 257 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAL12_RS07185 6aa204645473b2daf8c64c8ad9c5caa9 408 Gene3D G3DSA:3.90.1150.10 283 407 2.4E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS07185 6aa204645473b2daf8c64c8ad9c5caa9 408 Gene3D G3DSA:3.40.640.10 52 282 2.6E-71 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 SMART SM00228 496 566 9.3E-5 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 Pfam PF05299 M61 glycyl aminopeptidase 286 402 1.7E-47 T 06-07-2017 IPR007963 Peptidase M61, catalytic domain CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 Pfam PF13180 PDZ domain 500 575 7.8E-12 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 PIRSF PIRSF016493 2 588 2.7E-209 T 06-07-2017 IPR024191 Peptidase M61 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 SUPERFAMILY SSF50156 509 577 1.04E-13 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 Gene3D G3DSA:2.30.42.10 507 579 1.7E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS25845 2ed5d199208c602b316303681df9b854 588 SUPERFAMILY SSF55486 244 433 6.08E-9 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 463 3.8E-39 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 304 3.8E-39 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 324 342 3.8E-39 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 428 3.8E-39 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 175 3.8E-39 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Pfam PF00364 Biotin-requiring enzyme 6 76 2.6E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 SUPERFAMILY SSF51230 3 94 5.76E-22 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 476 4.4E-56 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Gene3D G3DSA:2.40.50.100 5 80 1.0E-20 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 491 512 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 556 571 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 456 463 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 298 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 177 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 188 203 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 324 349 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 427 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 578 598 9.2E-70 T 06-07-2017 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Gene3D G3DSA:3.30.390.30 490 608 6.5E-48 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 SUPERFAMILY SSF51905 151 485 1.17E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Gene3D G3DSA:3.50.50.60 420 488 2.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Gene3D G3DSA:3.50.50.60 153 297 2.6E-66 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 SUPERFAMILY SSF55424 493 613 6.36E-41 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 495 603 1.9E-36 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 Gene3D G3DSA:3.50.50.60 305 419 5.1E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 189 199 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAL12_RS11750 a65a1c1cb43e5d6fd5fe3cf2f6b7836f 620 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 154 608 3.5E-148 T 06-07-2017 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:3.40.50.300 2 105 4.9E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:3.40.50.300 182 279 4.9E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Pfam PF00580 UvrD/REP helicase N-terminal domain 5 265 1.8E-73 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:1.10.486.10 382 505 1.6E-43 T 06-07-2017 CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:1.10.486.10 540 558 1.6E-43 T 06-07-2017 CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Pfam PF13361 UvrD-like helicase C-terminal domain 271 633 1.3E-71 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:3.40.50.300 280 381 9.0E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:3.40.50.300 569 661 9.0E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 SUPERFAMILY SSF52540 3 505 8.13E-178 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 SUPERFAMILY SSF52540 570 658 8.13E-178 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17265 880f3c3a63c90194262ddea30634afed 765 Gene3D G3DSA:1.10.10.160 109 181 2.8E-18 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 Gene3D G3DSA:3.30.390.30 331 453 3.6E-31 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 Gene3D G3DSA:3.50.50.60 137 330 1.1E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 276 2.7E-24 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.7E-24 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 2.7E-24 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.7E-24 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 2.7E-24 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 450 3.3E-23 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 Gene3D G3DSA:3.50.50.60 5 136 6.7E-35 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 06-07-2017 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PIRSF PIRSF000350 2 435 1.4E-88 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 313 6.3E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 SUPERFAMILY SSF55424 346 453 9.11E-29 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 SUPERFAMILY SSF51905 4 363 2.46E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 427 447 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 198 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 275 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 1.1E-44 T 06-07-2017 CAL12_RS16030 26cca5061ebc41a0a5f040e0e78a0b93 460 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.1E-44 T 06-07-2017 CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 Gene3D G3DSA:1.10.10.10 1 84 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 Pfam PF03466 LysR substrate binding domain 85 294 9.8E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 SUPERFAMILY SSF46785 1 84 2.91E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 Gene3D G3DSA:3.40.190.10 193 273 2.1E-15 T 06-07-2017 CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.2E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 SUPERFAMILY SSF53850 87 308 2.02E-31 T 06-07-2017 CAL12_RS18115 eba489421a38f8de9400e6ddf34dda9b 318 Gene3D G3DSA:3.40.190.10 88 192 2.2E-22 T 06-07-2017 CAL12_RS06795 5e03205637e03e582808ddc70baa18bc 350 Gene3D G3DSA:1.10.1530.10 11 79 1.0E-16 T 06-07-2017 CAL12_RS06795 5e03205637e03e582808ddc70baa18bc 350 Pfam PF02615 Malate/L-lactate dehydrogenase 13 341 1.4E-110 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS06795 5e03205637e03e582808ddc70baa18bc 350 SUPERFAMILY SSF89733 10 347 4.05E-106 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS06795 5e03205637e03e582808ddc70baa18bc 350 Gene3D G3DSA:3.30.1370.60 80 279 4.3E-74 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 SUPERFAMILY SSF52540 1 204 1.39E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 SUPERFAMILY SSF52540 438 577 1.39E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:1.20.1580.10 405 485 7.2E-51 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:1.20.1580.10 249 282 7.2E-51 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:1.20.1580.10 92 129 7.2E-51 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.30.1490.20 200 247 8.0E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.30.1490.20 130 153 8.0E-25 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 ProSitePatterns PS00211 ABC transporters family signature. 837 851 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.40.50.300 3 51 4.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.40.50.300 828 949 4.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.40.50.300 486 604 4.8E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:3.40.50.300 623 679 4.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:1.10.8.280 286 404 1.5E-38 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 947 22.155 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 Gene3D G3DSA:1.20.1580.10 701 827 7.1E-53 T 06-07-2017 CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 SUPERFAMILY SSF52540 629 928 7.31E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27405 ab2d82ceb85a0e193accc74b82525862 965 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 932 0.0 T 06-07-2017 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CAL12_RS03940 9567dd7c0ba5930448c0c7b6d64da7c0 326 SUPERFAMILY SSF51182 21 293 7.29E-50 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03940 9567dd7c0ba5930448c0c7b6d64da7c0 326 PIRSF PIRSF006232 14 296 2.6E-47 T 06-07-2017 IPR012093 Pirin CAL12_RS03940 9567dd7c0ba5930448c0c7b6d64da7c0 326 Gene3D G3DSA:2.60.120.10 44 259 5.5E-46 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS03940 9567dd7c0ba5930448c0c7b6d64da7c0 326 Pfam PF05726 Pirin C-terminal cupin domain 183 287 4.0E-15 T 06-07-2017 IPR008778 Pirin, C-terminal domain CAL12_RS03940 9567dd7c0ba5930448c0c7b6d64da7c0 326 Pfam PF02678 Pirin 56 129 5.8E-10 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAL12_RS02495 b34b475ea1ed268c02927d019884cb87 265 SUPERFAMILY SSF52540 19 242 1.24E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02495 b34b475ea1ed268c02927d019884cb87 265 SMART SM00382 41 222 2.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02495 b34b475ea1ed268c02927d019884cb87 265 Gene3D G3DSA:3.40.50.300 11 227 7.5E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02495 b34b475ea1ed268c02927d019884cb87 265 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02495 b34b475ea1ed268c02927d019884cb87 265 Pfam PF00005 ABC transporter 34 171 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 188 295 1.7E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 36 148 1.2E-22 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 171 715 9.4E-150 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 SUPERFAMILY SSF54665 19 156 3.93E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 472 620 3.0E-40 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.90.1170.50 17 137 1.9E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 SUPERFAMILY SSF56003 141 777 7.07E-163 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 SMART SM01008 35 149 4.8E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 630 780 9.4E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 375 471 9.4E-60 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 138 187 3.8E-26 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00160 d64f862d6aae1e7701ead69b19d74cc4 793 Gene3D G3DSA:3.30.365.10 297 372 3.8E-26 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10525 d1230e20704f839c342ee7b2c7c10843 291 Pfam PF05425 Copper resistance protein D 186 285 1.4E-17 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Gene3D G3DSA:3.10.20.30 217 315 8.7E-21 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Pfam PF00970 Oxidoreductase FAD-binding domain 11 103 1.5E-4 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 SUPERFAMILY SSF52343 99 224 2.1E-27 T 06-07-2017 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 308 1.7E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 268 276 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 SUPERFAMILY SSF63380 7 100 3.78E-24 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Gene3D G3DSA:2.40.30.10 6 100 2.8E-29 T 06-07-2017 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 191 199 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 77 91 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 41 53 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 53 67 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 31 41 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 PRINTS PR00409 Phthalate dioxygenase reductase family signature 91 105 1.4E-39 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 SUPERFAMILY SSF54292 211 315 3.28E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Pfam PF00175 Oxidoreductase NAD-binding domain 114 205 7.6E-6 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS04020 537208953e5eeffb7f5c37d78cbca434 316 Gene3D G3DSA:3.40.50.80 103 216 4.4E-24 T 06-07-2017 CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 SUPERFAMILY SSF51735 1 155 2.03E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 Gene3D G3DSA:3.40.50.720 1 155 1.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 153 1.0E-28 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 SUPERFAMILY SSF48179 159 277 7.03E-29 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 PIRSF PIRSF000103 1 282 3.1E-69 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 160 276 1.2E-22 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS16480 031c4111ee10931d9c69d386ecf698eb 286 Gene3D G3DSA:1.10.1040.10 160 278 1.6E-31 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 06-07-2017 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 37.468 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 SUPERFAMILY SSF53850 6 220 1.09E-78 T 06-07-2017 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 1.4E-42 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 1.4E-42 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 1.4E-42 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 1.4E-42 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 1.4E-42 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 227 296 7.0E-17 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Gene3D G3DSA:3.40.190.10 6 111 1.7E-44 T 06-07-2017 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 214 7.1E-74 T 06-07-2017 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 298 6.2E-106 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 PIRSF PIRSF001438 2 310 5.0E-112 T 06-07-2017 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Gene3D G3DSA:3.40.190.10 112 200 3.3E-37 T 06-07-2017 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 Gene3D G3DSA:3.30.160.40 224 306 1.9E-26 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09520 640efdf3ea22047d7ab0dc85e07bca95 311 SUPERFAMILY SSF54782 223 307 2.62E-25 T 06-07-2017 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 SUPERFAMILY SSF56931 196 430 7.98E-55 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 Gene3D G3DSA:2.40.230.10 205 431 5.3E-56 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 Pfam PF02253 Phospholipase A1 210 429 8.4E-37 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 PRINTS PR01486 Bacterial phospholipase A1 protein signature 401 421 2.0E-10 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 PRINTS PR01486 Bacterial phospholipase A1 protein signature 211 228 2.0E-10 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 PRINTS PR01486 Bacterial phospholipase A1 protein signature 341 359 2.0E-10 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS06910 705a3412670d34343501a338d85a9aad 431 PRINTS PR01486 Bacterial phospholipase A1 protein signature 289 303 2.0E-10 T 06-07-2017 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 Gene3D G3DSA:3.30.450.20 8 116 2.4E-10 T 06-07-2017 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 SUPERFAMILY SSF55785 21 120 4.89E-11 T 06-07-2017 IPR000014 PAS domain CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 Pfam PF00196 Bacterial regulatory proteins, luxR family 126 178 3.6E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 SUPERFAMILY SSF46894 109 182 9.52E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 SMART SM00421 123 180 4.6E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 119 2.0E-9 T 06-07-2017 IPR000014 PAS domain CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 Pfam PF13426 PAS domain 16 117 2.8E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 Gene3D G3DSA:1.10.10.10 124 181 1.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 ProSitePatterns PS00622 LuxR-type HTH domain signature. 140 167 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 126 140 1.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 168 1.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24400 a543d069ce02dee6978328296a5797c5 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 156 1.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 SUPERFAMILY SSF64288 63 236 4.87E-33 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 SUPERFAMILY SSF46785 7 74 7.37E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 6.8E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 6.8E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 SMART SM00345 16 75 1.8E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.1E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 Pfam PF07702 UTRA domain 101 231 4.4E-31 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 Gene3D G3DSA:1.10.10.10 9 68 2.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 Gene3D G3DSA:3.40.1410.10 69 235 3.9E-34 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS21375 25827eaf63f4fefab133aa62803bc3be 251 SMART SM00866 93 231 9.1E-25 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 8 120 15.915 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 12 115 2.5E-18 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 Gene3D G3DSA:3.30.300.20 11 118 5.7E-27 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 100 3.0E-38 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 Pfam PF02033 Ribosome-binding factor A 12 113 2.6E-22 T 06-07-2017 IPR000238 Ribosome-binding factor A GO:0006364 CAL12_RS18425 acb7fba38086ee24752824a9cb9e3b90 133 SUPERFAMILY SSF89919 12 116 4.45E-25 T 06-07-2017 IPR023799 Ribosome-binding factor A domain CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:2.40.50.180 607 671 4.4E-13 T 06-07-2017 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SMART SM01231 336 399 2.0E-21 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SUPERFAMILY SSF47226 6 128 8.64E-31 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SUPERFAMILY SSF55874 402 582 7.07E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SUPERFAMILY SSF50341 583 714 4.97E-31 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 337 399 1.7E-16 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Pfam PF09078 CheY binding 187 249 1.5E-25 T 06-07-2017 IPR015162 CheY binding CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:1.10.287.560 337 400 9.8E-23 T 06-07-2017 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 3.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 568 581 3.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 544 562 3.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 PRINTS PR00344 Bacterial sensor protein C-terminal signature 489 503 3.2E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SMART SM00387 444 584 8.1E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SMART SM00260 576 716 2.2E-40 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SUPERFAMILY SSF55052 186 251 2.25E-20 T 06-07-2017 IPR015162 CheY binding CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Pfam PF01584 CheW-like domain 589 717 9.2E-27 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SUPERFAMILY SSF47384 337 400 1.18E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 SMART SM00073 6 104 2.4E-29 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 447 583 1.5E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:3.30.565.10 401 583 1.4E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Pfam PF01627 Hpt domain 9 109 2.0E-18 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:2.30.30.40 672 715 1.2E-23 T 06-07-2017 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:2.30.30.40 584 605 1.2E-23 T 06-07-2017 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:1.20.120.160 6 146 3.3E-39 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS11825 c78766e3b7af5e3e5f23484ba462926c 731 Gene3D G3DSA:3.30.70.400 185 251 2.6E-23 T 06-07-2017 IPR015162 CheY binding CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 SUPERFAMILY SSF53850 91 297 1.04E-39 T 06-07-2017 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 Gene3D G3DSA:1.10.10.10 1 80 2.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 Pfam PF03466 LysR substrate binding domain 90 293 2.1E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 Gene3D G3DSA:3.40.190.10 177 266 5.0E-19 T 06-07-2017 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 SUPERFAMILY SSF46785 3 84 5.53E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12665 09cfc63ff30c21f794f70dcb7e59a94d 311 Gene3D G3DSA:3.40.190.10 91 176 1.4E-20 T 06-07-2017 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 Pfam PF00701 Dihydrodipicolinate synthetase family 8 292 5.4E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 SMART SM01130 6 295 1.7E-58 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 SUPERFAMILY SSF51569 4 295 2.2E-63 T 06-07-2017 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 Gene3D G3DSA:3.20.20.70 3 296 3.9E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 PIRSF PIRSF001365 2 303 1.3E-51 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 6.5E-5 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24125 43d45a871e303c00e80ec405ea891dfa 307 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 6.5E-5 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 Pfam PF03466 LysR substrate binding domain 95 292 2.2E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 Gene3D G3DSA:3.40.190.10 96 178 4.1E-29 T 06-07-2017 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 Gene3D G3DSA:3.40.190.10 179 262 3.0E-21 T 06-07-2017 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 Gene3D G3DSA:1.10.10.10 2 87 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 SUPERFAMILY SSF53850 95 296 2.35E-36 T 06-07-2017 CAL12_RS07725 3f7e56e5fd5921457776c1ac9599db97 301 SUPERFAMILY SSF46785 2 87 4.57E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21735 d583e28d0ec173e65f0ad0d9604e0f8e 349 SUPERFAMILY SSF51430 1 347 2.36E-108 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS21735 d583e28d0ec173e65f0ad0d9604e0f8e 349 Gene3D G3DSA:3.20.20.100 2 346 2.2E-108 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS21735 d583e28d0ec173e65f0ad0d9604e0f8e 349 Pfam PF00248 Aldo/keto reductase family 16 340 2.6E-75 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 SUPERFAMILY SSF103473 7 197 3.4E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 SUPERFAMILY SSF103473 244 446 3.4E-53 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 Pfam PF07690 Major Facilitator Superfamily 15 404 6.2E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 Gene3D G3DSA:1.20.1250.20 11 186 1.5E-23 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 Gene3D G3DSA:1.20.1250.20 260 447 5.2E-11 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 3.8E-9 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 330 350 3.8E-9 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 3.8E-9 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 3.8E-9 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 3.8E-9 T 06-07-2017 CAL12_RS10890 5b3aac3ab231d878bbd4a32b394d37de 456 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 3.8E-9 T 06-07-2017 CAL12_RS04855 8fdfd536f1121568baec1f323e9b6aba 542 SUPERFAMILY SSF56317 239 505 6.54E-36 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS04855 8fdfd536f1121568baec1f323e9b6aba 542 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 69 487 6.3E-85 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAL12_RS04855 8fdfd536f1121568baec1f323e9b6aba 542 Gene3D G3DSA:3.60.110.10 237 501 1.1E-25 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS04855 8fdfd536f1121568baec1f323e9b6aba 542 Pfam PF00795 Carbon-nitrogen hydrolase 241 511 1.6E-26 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS04855 8fdfd536f1121568baec1f323e9b6aba 542 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 10 525 20.684 T 06-07-2017 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 SUPERFAMILY SSF55811 18 159 1.76E-32 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 Pfam PF00293 NUDIX domain 25 143 4.2E-21 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 PRINTS PR00502 NUDIX hydrolase family signature 63 78 9.6E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 PRINTS PR00502 NUDIX hydrolase family signature 49 63 9.6E-9 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS07375 1acf15f5c4971b09581a93aba37cb0f6 164 Gene3D G3DSA:3.90.79.10 24 161 6.3E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS11630 c4b0aa111671179a56ef8b6a1200b019 274 Gene3D G3DSA:3.60.15.10 32 248 1.7E-27 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11630 c4b0aa111671179a56ef8b6a1200b019 274 Pfam PF00753 Metallo-beta-lactamase superfamily 48 246 1.5E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11630 c4b0aa111671179a56ef8b6a1200b019 274 SUPERFAMILY SSF56281 37 250 1.31E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11630 c4b0aa111671179a56ef8b6a1200b019 274 SMART SM00849 46 246 2.0E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS02230 a8e5143be3e84ec546a2cafd2d95e7b7 334 Pfam PF05035 2-keto-3-deoxy-galactonokinase 15 323 6.2E-101 T 06-07-2017 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 CAL12_RS16000 5738113ded3f57b7667bb085b30bf2b3 430 PIRSF PIRSF005353 1 430 6.9E-175 T 06-07-2017 IPR026033 Purine permease PbuG-like CAL12_RS16000 5738113ded3f57b7667bb085b30bf2b3 430 Pfam PF00860 Permease family 18 388 6.0E-52 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS03185 cd7ca138a16341ace57ce7e0f65321c1 273 Gene3D G3DSA:1.10.3720.10 18 264 1.1E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03185 cd7ca138a16341ace57ce7e0f65321c1 273 SUPERFAMILY SSF161098 16 264 5.49E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03185 cd7ca138a16341ace57ce7e0f65321c1 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 265 1.1E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Pfam PF01751 Toprim domain 4 131 1.5E-12 T 06-07-2017 IPR006171 Toprim domain CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Pfam PF13342 C-terminal repeat of topoisomerase 754 814 2.3E-19 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Pfam PF13342 C-terminal repeat of topoisomerase 649 708 5.6E-21 T 06-07-2017 IPR025589 Topoisomerase C-terminal repeat CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Gene3D G3DSA:3.40.50.140 3 148 7.6E-39 T 06-07-2017 IPR006171 Toprim domain CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 SUPERFAMILY SSF56712 3 613 1.57E-167 T 06-07-2017 IPR023405 DNA topoisomerase, type IA, core domain CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 SMART SM00437 278 560 1.3E-78 T 06-07-2017 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Gene3D G3DSA:2.70.20.10 214 340 3.0E-20 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Gene3D G3DSA:2.70.20.10 373 490 2.3E-19 T 06-07-2017 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 330 - T 06-07-2017 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Gene3D G3DSA:1.10.460.10 493 613 1.4E-51 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Gene3D G3DSA:1.10.460.10 157 213 1.4E-51 T 06-07-2017 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 3.7E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 3.7E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 3.7E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 3.7E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 3.7E-25 T 06-07-2017 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 SMART SM00493 3 125 8.4E-16 T 06-07-2017 IPR006171 Toprim domain CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 Pfam PF01131 DNA topoisomerase 153 598 3.8E-113 T 06-07-2017 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 SMART SM00436 125 220 1.2E-20 T 06-07-2017 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CAL12_RS00455 bde968ee8c4be98a6a90236651d7b580 888 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 620 1.7E-166 T 06-07-2017 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 Gene3D G3DSA:2.120.10.30 28 313 1.5E-72 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 39 299 8.6E-67 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 SUPERFAMILY SSF63829 2 313 2.62E-71 T 06-07-2017 CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 40 57 9.1E-12 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 170 192 9.1E-12 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 236 253 9.1E-12 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS06975 8cc735fe475fc4578327229df1c6701f 315 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 281 299 9.1E-12 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS18420 161d5efcab994574d539dac35f3aac9d 245 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 182 233 1.1E-15 T 06-07-2017 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CAL12_RS18420 161d5efcab994574d539dac35f3aac9d 245 SUPERFAMILY SSF55120 8 227 2.1E-78 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS18420 161d5efcab994574d539dac35f3aac9d 245 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 220 2.3E-74 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS18420 161d5efcab994574d539dac35f3aac9d 245 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 181 1.5E-54 T 06-07-2017 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CAL12_RS18420 161d5efcab994574d539dac35f3aac9d 245 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 241 17.681 T 06-07-2017 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS17860 1491248a3dd3b91257e7aa639e6dcf2b 512 Pfam PF05872 Bacterial protein of unknown function (DUF853) 14 512 9.7E-232 T 06-07-2017 IPR033186 Helicase HerA-like C-terminal CAL12_RS17860 1491248a3dd3b91257e7aa639e6dcf2b 512 Gene3D G3DSA:3.40.50.300 24 114 1.0E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17860 1491248a3dd3b91257e7aa639e6dcf2b 512 Gene3D G3DSA:3.40.50.300 210 387 1.0E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17860 1491248a3dd3b91257e7aa639e6dcf2b 512 SUPERFAMILY SSF52540 9 389 6.0E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25265 ddbf5e57b978e153d1fd1323385fac93 302 PIRSF PIRSF003097 2 302 9.8E-49 T 06-07-2017 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CAL12_RS25265 ddbf5e57b978e153d1fd1323385fac93 302 Pfam PF02687 FtsX-like permease family 181 299 5.6E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 Gene3D G3DSA:1.10.357.10 72 210 7.9E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 8.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 8.2E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.7E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 SUPERFAMILY SSF48498 88 209 2.85E-32 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 Pfam PF08362 YcdC-like protein, C-terminal region 70 209 7.7E-31 T 06-07-2017 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 SUPERFAMILY SSF46689 9 90 2.46E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS24515 218f9b5e330de3295710d70f28b604a3 213 Gene3D G3DSA:1.10.10.60 11 71 2.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10490 564f3d1aec98782dae73229029ed8f30 277 SUPERFAMILY SSF161098 18 270 1.31E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10490 564f3d1aec98782dae73229029ed8f30 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 267 4.9E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10490 564f3d1aec98782dae73229029ed8f30 277 Gene3D G3DSA:1.10.3720.10 18 267 2.3E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 Gene3D G3DSA:1.10.10.10 1 82 9.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 Gene3D G3DSA:3.40.190.10 83 211 6.8E-15 T 06-07-2017 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 Gene3D G3DSA:3.40.190.10 212 268 9.3E-16 T 06-07-2017 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 SUPERFAMILY SSF46785 1 87 1.15E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 Pfam PF03466 LysR substrate binding domain 87 314 8.8E-24 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 SUPERFAMILY SSF53850 88 315 8.79E-23 T 06-07-2017 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.0E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10285 b529669703162f8c7edb9f7cd55d33de 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.7E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 Gene3D G3DSA:1.20.1600.10 59 475 2.9E-92 T 06-07-2017 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 SUPERFAMILY SSF56954 5 29 2.49E-94 T 06-07-2017 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 SUPERFAMILY SSF56954 61 475 2.49E-94 T 06-07-2017 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 Pfam PF02321 Outer membrane efflux protein 292 470 4.9E-20 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 Pfam PF02321 Outer membrane efflux protein 71 261 1.6E-20 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS16200 05b69ed13ecf671aa5d81230df4af15f 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 472 3.3E-86 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS18050 25049211eb8858a1f00cf87ee0ca4e5a 118 Gene3D G3DSA:3.40.30.10 5 117 2.6E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18050 25049211eb8858a1f00cf87ee0ca4e5a 118 Pfam PF03960 ArsC family 37 114 1.7E-12 T 06-07-2017 IPR006660 Arsenate reductase-like CAL12_RS18050 25049211eb8858a1f00cf87ee0ca4e5a 118 SUPERFAMILY SSF52833 5 116 2.85E-30 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18050 25049211eb8858a1f00cf87ee0ca4e5a 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 6 115 1.1E-26 T 06-07-2017 IPR006504 Transcriptional regulator Spx/MgsR CAL12_RS04885 ab368d8595ca69d52e8f82450c6f3943 127 SUPERFAMILY SSF55174 4 101 3.66E-26 T 06-07-2017 CAL12_RS04885 ab368d8595ca69d52e8f82450c6f3943 127 PIRSF PIRSF016821 2 127 3.3E-40 T 06-07-2017 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CAL12_RS04885 ab368d8595ca69d52e8f82450c6f3943 127 Pfam PF01479 S4 domain 6 49 1.9E-10 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS04885 ab368d8595ca69d52e8f82450c6f3943 127 Gene3D G3DSA:3.10.290.10 3 101 1.6E-30 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS04885 ab368d8595ca69d52e8f82450c6f3943 127 SMART SM00363 5 64 1.6E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 SUPERFAMILY SSF75304 589 728 1.47E-38 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 SUPERFAMILY SSF75304 759 794 1.47E-38 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 SUPERFAMILY SSF75304 196 495 1.47E-38 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 Pfam PF01425 Amidase 201 492 1.6E-31 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 Gene3D G3DSA:3.90.1300.10 199 497 8.1E-52 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 Gene3D G3DSA:3.90.1300.10 580 794 8.1E-52 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS02415 81281398c6fb4cfb569049ead0fb96b6 800 Gene3D G3DSA:3.90.1300.10 40 78 1.8E-5 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 Gene3D G3DSA:1.20.210.10 51 585 8.6E-188 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 1.3E-92 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 512 1.0E-138 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 656 0.0 T 06-07-2017 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 SUPERFAMILY SSF81442 53 569 2.49E-179 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21280 e326f8d8eeab0572b18c616c05f52c1b 667 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 316 4.4E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 Gene3D G3DSA:3.50.50.60 112 323 2.7E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 SUPERFAMILY SSF51905 2 169 2.73E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 SUPERFAMILY SSF51905 212 334 2.73E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 Gene3D G3DSA:3.50.50.60 2 111 5.0E-11 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 288 295 1.3E-6 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.3E-6 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 1.3E-6 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 3.0E-13 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.0E-13 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 295 3.0E-13 T 06-07-2017 CAL12_RS13890 5d5b38d79bb90dd2db130e95a5de1979 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.0E-13 T 06-07-2017 CAL12_RS06330 9bde9db1591bd2b94de777f37b97e339 329 SUPERFAMILY SSF53850 115 288 2.56E-14 T 06-07-2017 CAL12_RS06330 9bde9db1591bd2b94de777f37b97e339 329 PIRSF PIRSF017082 1 326 2.4E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06330 9bde9db1591bd2b94de777f37b97e339 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 2.2E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18805 71d30271a48266d7f26d6b277cb05dbb 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 324 6.7E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18805 71d30271a48266d7f26d6b277cb05dbb 328 SUPERFAMILY SSF53850 119 284 3.04E-15 T 06-07-2017 CAL12_RS18805 71d30271a48266d7f26d6b277cb05dbb 328 PIRSF PIRSF017082 1 327 6.3E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18805 71d30271a48266d7f26d6b277cb05dbb 328 Gene3D G3DSA:3.40.190.10 131 232 1.3E-6 T 06-07-2017 CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 Pfam PF00593 TonB dependent receptor 426 649 3.6E-28 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 SUPERFAMILY SSF56935 45 649 3.83E-107 T 06-07-2017 CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 52 - T 06-07-2017 IPR010916 TonB box, conserved site CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 Gene3D G3DSA:2.170.130.10 37 170 1.9E-39 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 Gene3D G3DSA:2.40.170.20 171 649 1.7E-74 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS25540 270c0e7d38b6ad570856932606aa4b56 650 Pfam PF07715 TonB-dependent Receptor Plug Domain 58 164 6.6E-26 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS17975 af87df70da241d991e123409348ccd9b 258 Pfam PF00535 Glycosyl transferase family 2 4 106 4.1E-16 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS17975 af87df70da241d991e123409348ccd9b 258 SUPERFAMILY SSF53448 1 146 2.25E-28 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS17975 af87df70da241d991e123409348ccd9b 258 Gene3D G3DSA:3.90.550.10 1 105 6.3E-15 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 Gene3D G3DSA:2.170.130.10 12 132 1.3E-29 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 SUPERFAMILY SSF56935 16 704 4.63E-124 T 06-07-2017 CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 Pfam PF07715 TonB-dependent Receptor Plug Domain 27 124 2.2E-17 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 Pfam PF00593 TonB dependent receptor 461 702 1.4E-36 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 28 702 2.0E-82 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS19630 e95de33eb2680a04e83e33d7419b05f0 704 Gene3D G3DSA:2.40.170.20 140 704 2.2E-147 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 192 9.5E-33 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 Gene3D G3DSA:1.10.150.240 21 86 1.5E-18 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 SUPERFAMILY SSF56784 1 221 1.97E-53 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 Gene3D G3DSA:3.40.50.1000 87 221 5.9E-44 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 Gene3D G3DSA:3.40.50.1000 1 20 5.9E-44 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 191 1.3E-8 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 217 1.2E-59 T 06-07-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 2.8E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 2.8E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 2.8E-5 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS26100 e5f2610bb2f1bb4de5bd89b93f21ea83 247 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 186 2.2E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS20335 dcd3484aecc9a7b0c44ed6b5edfbc147 137 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 34.759 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAL12_RS20335 dcd3484aecc9a7b0c44ed6b5edfbc147 137 Gene3D G3DSA:2.40.50.140 1 137 3.2E-51 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20335 dcd3484aecc9a7b0c44ed6b5edfbc147 137 SUPERFAMILY SSF50249 3 137 9.25E-50 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20335 dcd3484aecc9a7b0c44ed6b5edfbc147 137 Pfam PF00436 Single-strand binding protein family 4 109 1.5E-38 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAL12_RS20335 dcd3484aecc9a7b0c44ed6b5edfbc147 137 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 125 6.8E-48 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAL12_RS01760 6b0418e2ec342f2668cc6383f77ad384 409 Gene3D G3DSA:3.40.50.10540 319 405 1.2E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01760 6b0418e2ec342f2668cc6383f77ad384 409 Gene3D G3DSA:3.40.50.10540 5 230 1.2E-118 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01760 6b0418e2ec342f2668cc6383f77ad384 409 SUPERFAMILY SSF89796 4 408 1.57E-142 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01760 6b0418e2ec342f2668cc6383f77ad384 409 Gene3D G3DSA:3.30.1540.10 236 318 2.2E-31 T 06-07-2017 CAL12_RS01760 6b0418e2ec342f2668cc6383f77ad384 409 Pfam PF02515 CoA-transferase family III 8 386 3.7E-130 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS18935 1a3b8262979b33ce39cc858d2c8377fc 297 Gene3D G3DSA:3.40.50.720 12 191 1.2E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18935 1a3b8262979b33ce39cc858d2c8377fc 297 Pfam PF02153 Prephenate dehydrogenase 28 284 3.5E-66 T 06-07-2017 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CAL12_RS18935 1a3b8262979b33ce39cc858d2c8377fc 297 SUPERFAMILY SSF51735 16 181 5.16E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18935 1a3b8262979b33ce39cc858d2c8377fc 297 SUPERFAMILY SSF48179 185 293 5.21E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 227 2.7E-37 T 06-07-2017 CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 SUPERFAMILY SSF51735 2 228 4.08E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 211 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 158 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 1.6E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10575 85a8f437ea3cf2fd565786d33612c14f 229 Gene3D G3DSA:3.40.50.720 2 228 4.7E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Gene3D G3DSA:3.50.50.60 18 97 3.3E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Gene3D G3DSA:3.50.50.60 325 381 3.3E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Gene3D G3DSA:3.50.50.60 163 240 3.3E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Pfam PF01266 FAD dependent oxidoreductase 19 360 1.5E-47 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Gene3D G3DSA:3.30.9.10 107 162 2.2E-5 T 06-07-2017 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 Gene3D G3DSA:3.30.9.10 241 321 2.2E-5 T 06-07-2017 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 SUPERFAMILY SSF51905 325 381 2.05E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 SUPERFAMILY SSF51905 19 241 2.05E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07100 6a49b890adca36ee804410a288247f41 385 SUPERFAMILY SSF54373 241 323 1.44E-10 T 06-07-2017 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 Gene3D G3DSA:3.40.190.10 210 292 4.5E-20 T 06-07-2017 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 Gene3D G3DSA:1.10.10.10 31 116 2.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 Gene3D G3DSA:3.40.190.10 125 209 9.8E-29 T 06-07-2017 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 Pfam PF03466 LysR substrate binding domain 121 323 2.9E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 39 97 3.7E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 SUPERFAMILY SSF53850 122 325 2.71E-37 T 06-07-2017 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 74 85 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 74 4.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10040 471b8d6b3c35cd2aefe36c8ef639ef2a 329 SUPERFAMILY SSF46785 34 116 1.77E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08765 dee2de7ba2cd00aa6bee03e9460c9fc7 328 PIRSF PIRSF017082 1 328 1.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08765 dee2de7ba2cd00aa6bee03e9460c9fc7 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 8.4E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08765 dee2de7ba2cd00aa6bee03e9460c9fc7 328 SUPERFAMILY SSF53850 119 290 1.47E-10 T 06-07-2017 CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 SMART SM00316 4 72 0.0058 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 SUPERFAMILY SSF50249 1 71 1.37E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 25.536 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 1.9E-29 T 06-07-2017 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 Gene3D G3DSA:2.40.50.140 1 72 1.5E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS05055 9d15c2c92b9b4ab48a1e5de191db5522 87 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 4.4E-22 T 06-07-2017 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CAL12_RS04235 343e495a1466bdf3d406a4e328022434 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 94 1.9E-17 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS04235 343e495a1466bdf3d406a4e328022434 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 30 78 5.0E-14 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS04235 343e495a1466bdf3d406a4e328022434 159 SUPERFAMILY SSF69118 7 145 3.21E-43 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS04235 343e495a1466bdf3d406a4e328022434 159 Gene3D G3DSA:1.20.1290.10 3 147 1.2E-51 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS12605 66d63e4c792c46fa67501db4b6cb8a27 99 Gene3D G3DSA:3.40.30.10 4 96 8.4E-45 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS12605 66d63e4c792c46fa67501db4b6cb8a27 99 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 9 80 2.3E-20 T 06-07-2017 IPR011893 Selenoprotein, Rdx type CAL12_RS12605 66d63e4c792c46fa67501db4b6cb8a27 99 Pfam PF10262 Rdx family 8 81 3.1E-34 T 06-07-2017 IPR011893 Selenoprotein, Rdx type CAL12_RS12605 66d63e4c792c46fa67501db4b6cb8a27 99 SUPERFAMILY SSF52833 7 90 5.59E-29 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS20390 f724ad53ca500d850c3d1a6ce5918d9e 183 SMART SM00387 61 175 3.1E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS20390 f724ad53ca500d850c3d1a6ce5918d9e 183 Gene3D G3DSA:3.30.565.10 20 175 4.1E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS20390 f724ad53ca500d850c3d1a6ce5918d9e 183 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 62 162 2.4E-10 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS20390 f724ad53ca500d850c3d1a6ce5918d9e 183 SUPERFAMILY SSF55874 20 175 7.07E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 Gene3D G3DSA:3.40.47.10 21 116 2.5E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 Gene3D G3DSA:3.40.47.10 196 221 2.5E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 SUPERFAMILY SSF53901 179 354 3.71E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 SUPERFAMILY SSF53901 21 120 3.71E-31 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 Gene3D G3DSA:3.40.47.10 142 179 3.2E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 Gene3D G3DSA:3.40.47.10 242 364 3.2E-9 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS16285 dc20bd26fb9f2946f2db66d7503840f8 388 PIRSF PIRSF000429 1 387 3.8E-26 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS24790 40e9a929e7f173a5eb163dcb04371705 226 SUPERFAMILY SSF53474 16 225 2.53E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24790 40e9a929e7f173a5eb163dcb04371705 226 Gene3D G3DSA:3.40.50.1820 17 224 4.7E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24790 40e9a929e7f173a5eb163dcb04371705 226 Pfam PF02230 Phospholipase/Carboxylesterase 20 222 1.7E-53 T 06-07-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 SMART SM00354 1 72 7.0E-28 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 06-07-2017 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 SUPERFAMILY SSF53822 62 346 1.03E-63 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 Gene3D G3DSA:1.10.260.40 2 54 1.4E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 Gene3D G3DSA:3.40.50.2300 176 322 4.5E-42 T 06-07-2017 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 Pfam PF13377 Periplasmic binding protein-like domain 173 341 2.9E-38 T 06-07-2017 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 49 7.3E-16 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 SUPERFAMILY SSF47413 1 58 7.6E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS24050 475cc9c79b25307e64d527e61e408327 362 Gene3D G3DSA:3.40.50.2300 55 175 1.8E-35 T 06-07-2017 CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 Pfam PF00155 Aminotransferase class I and II 156 467 2.4E-30 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 1.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 Gene3D G3DSA:1.10.10.10 12 78 3.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 Gene3D G3DSA:3.40.640.10 157 359 5.8E-70 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 SMART SM00345 18 77 4.8E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 SUPERFAMILY SSF53383 108 477 9.34E-95 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 SUPERFAMILY SSF46785 11 85 2.27E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22755 ad5f049e0ae1d1071c76126b15138a3d 482 Gene3D G3DSA:3.90.1150.10 360 478 2.2E-9 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Gene3D G3DSA:3.50.50.60 512 580 1.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Gene3D G3DSA:3.50.50.60 243 349 1.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Gene3D G3DSA:3.50.50.60 5 158 1.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Gene3D G3DSA:3.50.50.60 454 467 1.2E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Pfam PF00732 GMC oxidoreductase 233 344 2.4E-10 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 SUPERFAMILY SSF51905 6 341 5.12E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 SUPERFAMILY SSF51905 521 582 5.12E-50 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14290 3f8d0104ef9099e422281abf77e7c387 591 Pfam PF05199 GMC oxidoreductase 448 571 5.9E-22 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 SUPERFAMILY SSF56176 2 154 6.54E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 2 154 2.0E-40 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 Gene3D G3DSA:3.30.465.10 42 154 5.3E-34 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 SMART SM01092 163 264 3.6E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 164 263 2.2E-14 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 Gene3D G3DSA:3.30.390.50 161 269 2.4E-22 T 06-07-2017 CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 SUPERFAMILY SSF55447 161 267 3.92E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS15640 1b8953c03576377828754b7abf322af0 276 Gene3D G3DSA:3.30.43.10 2 36 3.2E-10 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 SMART SM00387 348 459 1.8E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 4.7E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 SUPERFAMILY SSF55874 292 452 1.14E-32 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 Pfam PF00672 HAMP domain 164 232 7.0E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 Gene3D G3DSA:1.10.287.130 237 290 6.8E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 349 455 7.6E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 1.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.7E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 6 457 7.4E-132 T 06-07-2017 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 SUPERFAMILY SSF47384 220 303 1.0E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 SMART SM00388 237 303 3.6E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 Gene3D G3DSA:3.30.565.10 291 452 1.2E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS23250 4ac99e7ba1cb98df623585845b9b7767 459 SMART SM00304 183 236 1.3E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS14545 63fb21a156452f43ed379f5e25d24761 348 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 70 343 7.1E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14545 63fb21a156452f43ed379f5e25d24761 348 PIRSF PIRSF017082 14 347 6.2E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14545 63fb21a156452f43ed379f5e25d24761 348 SUPERFAMILY SSF53850 114 309 3.94E-12 T 06-07-2017 CAL12_RS04600 866be8177b79473d9205fee7b50e7abe 478 Gene3D G3DSA:3.40.309.10 263 450 4.9E-60 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS04600 866be8177b79473d9205fee7b50e7abe 478 Pfam PF00171 Aldehyde dehydrogenase family 16 474 4.3E-157 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS04600 866be8177b79473d9205fee7b50e7abe 478 SUPERFAMILY SSF53720 8 475 4.84E-155 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS04600 866be8177b79473d9205fee7b50e7abe 478 Gene3D G3DSA:3.40.605.10 9 262 4.3E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 Gene3D G3DSA:2.40.50.100 53 85 6.0E-16 T 06-07-2017 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 Gene3D G3DSA:2.40.50.100 220 253 6.0E-16 T 06-07-2017 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 SUPERFAMILY SSF111369 122 181 1.19E-5 T 06-07-2017 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 SUPERFAMILY SSF111369 169 275 1.19E-9 T 06-07-2017 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 Pfam PF00529 HlyD membrane-fusion protein of T1SS 27 351 9.8E-13 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 295 6.4E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS17840 949db18dc744501873e3cc62ce2f7ea8 397 SUPERFAMILY SSF111369 51 105 1.83E-5 T 06-07-2017 CAL12_RS12130 5c1997d7a3eaa7e077e0348f72592f60 186 Gene3D G3DSA:1.10.132.20 67 186 1.1E-43 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAL12_RS12130 5c1997d7a3eaa7e077e0348f72592f60 186 Pfam PF01765 Ribosome recycling factor 21 184 3.5E-61 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAL12_RS12130 5c1997d7a3eaa7e077e0348f72592f60 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 1.1E-67 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAL12_RS12130 5c1997d7a3eaa7e077e0348f72592f60 186 SUPERFAMILY SSF55194 5 185 3.79E-69 T 06-07-2017 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CAL12_RS12130 5c1997d7a3eaa7e077e0348f72592f60 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.645 T 06-07-2017 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 Gene3D G3DSA:3.30.450.40 83 250 1.8E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 Pfam PF09339 IclR helix-turn-helix domain 15 67 1.2E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 Pfam PF01614 Bacterial transcriptional regulator 136 255 3.0E-10 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 SMART SM00346 13 104 1.1E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 Gene3D G3DSA:1.10.10.10 7 82 1.6E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 SUPERFAMILY SSF46785 14 87 5.99E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03860 8d36c0c574e12d54750a9d83e47a4b06 282 SUPERFAMILY SSF55781 81 256 4.32E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 SUPERFAMILY SSF46767 77 158 3.27E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 6 70 1.6E-5 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 Gene3D G3DSA:1.10.10.10 77 162 1.1E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 160 38.197 T 06-07-2017 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 79 158 2.2E-31 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 SUPERFAMILY SSF53155 5 83 1.82E-16 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS20565 47076a38e0f0b9c32e3a9f45a9b4cc7c 173 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 78 157 8.8E-36 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS06720 271d6878ee3b6ddc463647d44ab76171 181 SUPERFAMILY SSF81342 7 175 1.26E-29 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS06720 271d6878ee3b6ddc463647d44ab76171 181 Gene3D G3DSA:1.20.950.20 7 72 7.5E-5 T 06-07-2017 CAL12_RS06720 271d6878ee3b6ddc463647d44ab76171 181 Pfam PF01292 Prokaryotic cytochrome b561 8 174 4.8E-27 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 Gene3D G3DSA:3.40.50.2300 9 154 2.9E-23 T 06-07-2017 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 5.5E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 Pfam PF00072 Response regulator receiver domain 12 122 1.1E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 SUPERFAMILY SSF52172 9 131 4.27E-22 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 SMART SM00448 10 125 3.1E-13 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 Gene3D G3DSA:1.10.10.10 155 211 9.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 SUPERFAMILY SSF46894 146 210 4.42E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 5.9E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 5.9E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 5.9E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS09745 f37db3b33b966e08b99f3350cf5993bc 219 SMART SM00421 152 209 5.9E-13 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25235 6adc73483411048b13beb0cf4150c786 207 Pfam PF07336 Putative stress-induced transcription regulator 16 152 7.7E-18 T 06-07-2017 IPR010852 Putative stress-induced transcription regulator CAL12_RS25235 6adc73483411048b13beb0cf4150c786 207 Gene3D G3DSA:1.10.3300.10 5 202 1.5E-49 T 06-07-2017 IPR023286 ABATE domain CAL12_RS25235 6adc73483411048b13beb0cf4150c786 207 SUPERFAMILY SSF160904 5 200 2.09E-44 T 06-07-2017 CAL12_RS25235 6adc73483411048b13beb0cf4150c786 207 Pfam PF11706 CGNR zinc finger 159 201 4.9E-19 T 06-07-2017 IPR021005 Zinc finger, CGNR CAL12_RS16910 e38f4b408f0f0d1eadce50fdec415833 276 SUPERFAMILY SSF51735 1 271 1.05E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16910 e38f4b408f0f0d1eadce50fdec415833 276 Gene3D G3DSA:3.40.50.720 1 229 2.4E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16910 e38f4b408f0f0d1eadce50fdec415833 276 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 8.2E-31 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 467 591 4.7E-39 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Gene3D G3DSA:1.20.58.100 450 559 2.2E-36 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 PIRSF PIRSF000171 4 581 4.8E-41 T 06-07-2017 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 SUPERFAMILY SSF51905 363 431 8.16E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 SUPERFAMILY SSF51905 9 264 8.16E-80 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 SUPERFAMILY SSF46977 456 592 3.27E-44 T 06-07-2017 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 393 2.6E-6 T 06-07-2017 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 2.6E-6 T 06-07-2017 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Gene3D G3DSA:3.50.50.60 355 428 4.8E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Gene3D G3DSA:3.50.50.60 7 247 4.8E-122 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 06-07-2017 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 2.3E-277 T 06-07-2017 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Pfam PF00890 FAD binding domain 14 408 1.6E-118 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 2.2E-239 T 06-07-2017 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 SUPERFAMILY SSF56425 241 359 5.83E-43 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Gene3D G3DSA:4.10.80.40 560 592 1.1E-24 T 06-07-2017 CAL12_RS19260 bad4b07550ea980b68fc1e22768f0acb 592 Gene3D G3DSA:3.90.700.10 248 354 1.3E-40 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07760 f47b803aac5d6d5294caf0e650c177b5 250 SUPERFAMILY SSF161098 51 232 7.98E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07760 f47b803aac5d6d5294caf0e650c177b5 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 249 9.7E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07760 f47b803aac5d6d5294caf0e650c177b5 250 Gene3D G3DSA:1.10.3720.10 49 245 1.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10365 c1d976a639269149c78e20db82a8e006 325 Gene3D G3DSA:3.40.190.10 126 245 8.0E-4 T 06-07-2017 CAL12_RS10365 c1d976a639269149c78e20db82a8e006 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 319 2.5E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10365 c1d976a639269149c78e20db82a8e006 325 SUPERFAMILY SSF53850 114 285 1.21E-11 T 06-07-2017 CAL12_RS10365 c1d976a639269149c78e20db82a8e006 325 PIRSF PIRSF017082 4 324 2.2E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 Gene3D G3DSA:3.30.460.10 7 129 2.0E-30 T 06-07-2017 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 155 216 1.0E-8 T 06-07-2017 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 Hamap MF_01262 CCA-adding enzyme [cca]. 9 365 39.107 T 06-07-2017 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 Pfam PF01743 Poly A polymerase head domain 11 130 1.5E-15 T 06-07-2017 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 SUPERFAMILY SSF81301 8 127 6.87E-30 T 06-07-2017 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 SUPERFAMILY SSF81891 128 316 2.09E-34 T 06-07-2017 CAL12_RS26570 8ed4f177272c2503a6af84d220150993 368 Gene3D G3DSA:1.10.3090.10 130 316 2.0E-32 T 06-07-2017 CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 SUPERFAMILY SSF55060 160 275 5.76E-23 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 257 1.3E-71 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 273 32.456 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 Pfam PF00288 GHMP kinases N terminal domain 88 143 3.4E-10 T 06-07-2017 IPR006204 GHMP kinase N-terminal domain GO:0005524 CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 SUPERFAMILY SSF54211 6 156 3.79E-45 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 PIRSF PIRSF010376 2 293 2.2E-86 T 06-07-2017 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 Gene3D G3DSA:3.30.230.10 6 158 1.7E-53 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 Gene3D G3DSA:3.30.70.890 160 276 1.4E-28 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAL12_RS02790 deecd8411c888c4a08371aee484e94eb 314 Pfam PF08544 GHMP kinases C terminal 215 274 9.0E-6 T 06-07-2017 IPR013750 GHMP kinase, C-terminal domain CAL12_RS11765 11537db00d7873ddd790eea3dcac1eb9 293 SUPERFAMILY SSF51735 1 291 1.64E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11765 11537db00d7873ddd790eea3dcac1eb9 293 Gene3D G3DSA:3.40.50.720 1 203 2.2E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11765 11537db00d7873ddd790eea3dcac1eb9 293 Gene3D G3DSA:3.90.25.10 223 291 3.8E-9 T 06-07-2017 CAL12_RS11765 11537db00d7873ddd790eea3dcac1eb9 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 1.4E-33 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS11765 11537db00d7873ddd790eea3dcac1eb9 293 Gene3D G3DSA:3.90.25.10 204 220 5.6E-6 T 06-07-2017 CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 Gene3D G3DSA:3.40.50.300 348 593 1.2E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 SUPERFAMILY SSF52540 350 595 2.86E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 Pfam PF00005 ABC transporter 368 525 2.3E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 575 596 1.9E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 SMART SM00382 376 574 9.8E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19510 cd2608cd803e77f05da6e670316e11c3 617 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 302 2.6E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 8 418 4.0E-190 T 06-07-2017 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 Gene3D G3DSA:3.40.640.10 58 303 1.9E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 SUPERFAMILY SSF53383 24 418 1.48E-131 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 Pfam PF00202 Aminotransferase class-III 25 416 2.6E-125 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS20030 f67a66dbc83ef8ba316b3ea6254d635f 420 Gene3D G3DSA:3.90.1150.10 304 418 2.2E-38 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 SUPERFAMILY SSF46785 9 91 3.01E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 SMART SM00895 82 205 4.9E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 SMART SM00345 14 72 8.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 72 9.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 Pfam PF07729 FCD domain 82 204 4.7E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 Gene3D G3DSA:1.10.10.10 6 73 1.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 Gene3D G3DSA:1.20.120.530 75 210 6.7E-32 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS00505 27acafcd99e4d5c0762658eaa6f43b74 228 SUPERFAMILY SSF48008 79 208 2.22E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25125 ca9711f1dbfc0da8536b5dbb536cb48e 266 Pfam PF04170 NlpE N-terminal domain 147 229 8.8E-7 T 06-07-2017 IPR007298 Copper resistance lipoprotein NlpE CAL12_RS23795 6c59b13b5a64b4c3703bb16d202cf80a 90 SUPERFAMILY SSF89447 6 66 1.88E-5 T 06-07-2017 CAL12_RS12920 abf16e382cf366276070877f3327e440 320 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 147 168 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS12920 abf16e382cf366276070877f3327e440 320 SUPERFAMILY SSF50129 3 152 1.37E-31 T 06-07-2017 IPR011032 GroES-like CAL12_RS12920 abf16e382cf366276070877f3327e440 320 Pfam PF13602 Zinc-binding dehydrogenase 189 308 1.8E-28 T 06-07-2017 CAL12_RS12920 abf16e382cf366276070877f3327e440 320 Gene3D G3DSA:3.90.180.10 4 203 2.4E-59 T 06-07-2017 IPR011032 GroES-like CAL12_RS12920 abf16e382cf366276070877f3327e440 320 SUPERFAMILY SSF51735 119 236 4.16E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12920 abf16e382cf366276070877f3327e440 320 SMART SM00829 13 308 4.4E-31 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS17330 a318d3beb65b57ff1692e739a8b18f1b 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 337 2.4E-68 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS17330 a318d3beb65b57ff1692e739a8b18f1b 370 SUPERFAMILY SSF51395 1 353 5.19E-117 T 06-07-2017 CAL12_RS17330 a318d3beb65b57ff1692e739a8b18f1b 370 Gene3D G3DSA:3.20.20.70 1 351 7.8E-127 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS07385 99c8892aaf152a15300868bc659da8ee 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.3E-50 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAL12_RS07385 99c8892aaf152a15300868bc659da8ee 208 Pfam PF01300 Telomere recombination 23 198 1.6E-39 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAL12_RS07385 99c8892aaf152a15300868bc659da8ee 208 SUPERFAMILY SSF55821 1 203 2.38E-59 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS07385 99c8892aaf152a15300868bc659da8ee 208 Gene3D G3DSA:3.90.870.10 2 205 1.3E-58 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 SUPERFAMILY SSF51604 128 383 5.76E-68 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 140 2.8E-18 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 Gene3D G3DSA:3.20.20.120 145 382 3.4E-73 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 Pfam PF13378 Enolase C-terminal domain-like 163 377 6.4E-60 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 SUPERFAMILY SSF54826 15 144 3.54E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 Gene3D G3DSA:3.30.390.10 15 144 6.0E-34 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 SMART SM00922 160 256 8.6E-19 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 115 140 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS15860 808f1fd37195ce7d2ca96aa1137ba141 391 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 206 237 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 SUPERFAMILY SSF51735 3 228 2.56E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 0.0032 T 06-07-2017 CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 Gene3D G3DSA:3.40.50.720 4 228 6.7E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 Pfam PF00106 short chain dehydrogenase 8 197 5.3E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 9.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 9.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13825 9a99d56d69741edd72291c2d4c473f44 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 9.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02420 76720466bc08c786278858c008b429f3 346 SMART SM00382 52 252 6.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02420 76720466bc08c786278858c008b429f3 346 Pfam PF00005 ABC transporter 44 194 1.9E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02420 76720466bc08c786278858c008b429f3 346 SUPERFAMILY SSF52540 20 266 1.65E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02420 76720466bc08c786278858c008b429f3 346 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 246 311 3.0E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS02420 76720466bc08c786278858c008b429f3 346 Gene3D G3DSA:3.40.50.300 16 269 1.9E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02420 76720466bc08c786278858c008b429f3 346 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02420 76720466bc08c786278858c008b429f3 346 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 244 330 2.4E-26 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS26545 85f320ea742daf3e4dd48f588d702ecf 154 Pfam PF01230 HIT domain 27 100 2.3E-11 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAL12_RS26545 85f320ea742daf3e4dd48f588d702ecf 154 Gene3D G3DSA:3.30.428.10 6 141 1.7E-36 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS26545 85f320ea742daf3e4dd48f588d702ecf 154 SUPERFAMILY SSF54197 6 139 3.23E-34 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS14245 e168974e8a5f4b4146bde0a579a6c89c 206 Pfam PF12261 Thermostable hemolysin 28 196 3.6E-52 T 06-07-2017 IPR022050 Thermostable hemolysin CAL12_RS14245 e168974e8a5f4b4146bde0a579a6c89c 206 SUPERFAMILY SSF55729 40 164 1.51E-7 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02130 5dcbcf85c5d2c20fc6199b0e8ba17944 497 PIRSF PIRSF002457 3 497 2.5E-130 T 06-07-2017 IPR030676 Citrate carrier CitT-related CAL12_RS02130 5dcbcf85c5d2c20fc6199b0e8ba17944 497 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 36 491 1.5E-70 T 06-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CAL12_RS02130 5dcbcf85c5d2c20fc6199b0e8ba17944 497 Pfam PF00939 Sodium:sulfate symporter transmembrane region 20 497 1.1E-126 T 06-07-2017 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 Pfam PF02195 ParB-like nuclease domain 37 124 1.4E-16 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 33 207 1.6E-41 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 SUPERFAMILY SSF110849 37 131 1.18E-15 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 SMART SM00470 36 129 2.6E-20 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 Gene3D G3DSA:3.90.1530.10 39 135 1.7E-17 T 06-07-2017 CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 SUPERFAMILY SSF109709 123 230 1.28E-19 T 06-07-2017 CAL12_RS20570 ec86263794ce17a5cae762439892c03c 370 Pfam PF08535 KorB domain 149 230 4.0E-18 T 06-07-2017 IPR013741 Transcriptional repressor protein KorB CAL12_RS07605 9c9ce8a552a51be8baee6d6e81d8853d 231 SUPERFAMILY SSF48452 86 199 2.68E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS07605 9c9ce8a552a51be8baee6d6e81d8853d 231 Gene3D G3DSA:1.25.40.10 74 207 1.7E-18 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS07605 9c9ce8a552a51be8baee6d6e81d8853d 231 SMART SM00028 151 184 1.2E-4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS07605 9c9ce8a552a51be8baee6d6e81d8853d 231 Pfam PF04733 Coatomer epsilon subunit 127 192 1.2E-6 T 06-07-2017 CAL12_RS27005 bc7b442ec46605beadff8cb4a5ec55ec 298 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 8 293 6.1E-160 T 06-07-2017 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 CAL12_RS27005 bc7b442ec46605beadff8cb4a5ec55ec 298 Gene3D G3DSA:3.90.550.10 7 269 6.4E-69 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS27005 bc7b442ec46605beadff8cb4a5ec55ec 298 SUPERFAMILY SSF53448 7 293 3.83E-94 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS27005 bc7b442ec46605beadff8cb4a5ec55ec 298 Pfam PF00483 Nucleotidyl transferase 8 244 1.1E-72 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAL12_RS05905 2f22bd38f75bda410ec955e175e85d0b 408 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 67 286 1.2E-8 T 06-07-2017 IPR010520 UPF0255 family CAL12_RS05905 2f22bd38f75bda410ec955e175e85d0b 408 SUPERFAMILY SSF53474 32 395 6.65E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05905 2f22bd38f75bda410ec955e175e85d0b 408 Gene3D G3DSA:1.20.1440.110 32 139 2.1E-26 T 06-07-2017 CAL12_RS05905 2f22bd38f75bda410ec955e175e85d0b 408 Gene3D G3DSA:3.40.50.1820 145 393 4.2E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 Pfam PF13549 ATP-grasp domain 497 708 9.1E-54 T 06-07-2017 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 SUPERFAMILY SSF52210 143 294 4.06E-42 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 SUPERFAMILY SSF56059 500 711 3.24E-33 T 06-07-2017 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 Gene3D G3DSA:3.40.50.720 3 129 6.8E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 Pfam PF13380 CoA binding domain 11 134 3.9E-18 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 SUPERFAMILY SSF52210 300 451 3.14E-21 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 292 2.6E-52 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 Gene3D G3DSA:3.40.50.261 130 289 1.7E-32 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 SMART SM00881 7 102 2.0E-27 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS22825 0906f444bd74df2785c054ac143a2edb 712 SUPERFAMILY SSF51735 3 136 1.36E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06945 65f995b5fdcd13ead6e9fed5c4e671ad 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 65 88 4.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS06945 65f995b5fdcd13ead6e9fed5c4e671ad 257 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 58 4.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS06945 65f995b5fdcd13ead6e9fed5c4e671ad 257 Gene3D G3DSA:1.10.357.10 37 207 3.1E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS06945 65f995b5fdcd13ead6e9fed5c4e671ad 257 Pfam PF00440 Bacterial regulatory proteins, tetR family 45 89 4.5E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS06945 65f995b5fdcd13ead6e9fed5c4e671ad 257 SUPERFAMILY SSF46689 33 105 1.03E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20870 52d9cec30083085879eaa577a9be0b28 366 SUPERFAMILY SSF51735 301 358 4.23E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20870 52d9cec30083085879eaa577a9be0b28 366 SUPERFAMILY SSF51735 1 272 4.23E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20870 52d9cec30083085879eaa577a9be0b28 366 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 98 349 3.8E-44 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS20870 52d9cec30083085879eaa577a9be0b28 366 Gene3D G3DSA:3.30.1780.10 1 151 1.5E-30 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS20870 52d9cec30083085879eaa577a9be0b28 366 Gene3D G3DSA:3.40.50.720 152 329 1.3E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22735 59dc26ba4e4b2c5892f2daf9c5c99b3e 434 Pfam PF12294 Protein of unknown function (DUF3626) 255 416 3.0E-8 T 06-07-2017 IPR022074 Protein of unknown function DUF3626 CAL12_RS25055 b704d66d2cf73a06b2835a19451f328a 387 SUPERFAMILY SSF53822 23 383 1.86E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS25055 b704d66d2cf73a06b2835a19451f328a 387 Pfam PF13458 Periplasmic binding protein 23 361 6.8E-68 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS25055 b704d66d2cf73a06b2835a19451f328a 387 Gene3D G3DSA:3.40.50.2300 146 294 1.1E-23 T 06-07-2017 CAL12_RS25055 b704d66d2cf73a06b2835a19451f328a 387 Gene3D G3DSA:3.40.50.2300 18 145 1.4E-39 T 06-07-2017 CAL12_RS25055 b704d66d2cf73a06b2835a19451f328a 387 Gene3D G3DSA:3.40.50.2300 295 348 1.4E-39 T 06-07-2017 CAL12_RS23895 4761307c5813c0ed7d80a0c50280b56e 167 Gene3D G3DSA:3.40.30.10 1 166 5.2E-66 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23895 4761307c5813c0ed7d80a0c50280b56e 167 SUPERFAMILY SSF52833 1 165 2.91E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23895 4761307c5813c0ed7d80a0c50280b56e 167 Pfam PF08534 Redoxin 4 164 8.5E-40 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 207 226 2.5E-9 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 146 153 2.5E-9 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 130 140 2.5E-9 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 297 305 2.5E-9 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 SUPERFAMILY SSF54292 1 89 8.13E-26 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 SUPERFAMILY SSF63380 101 197 8.6E-20 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Gene3D G3DSA:2.40.30.10 101 197 2.6E-21 T 06-07-2017 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Gene3D G3DSA:3.40.50.80 201 331 1.5E-40 T 06-07-2017 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Pfam PF00175 Oxidoreductase NAD-binding domain 208 310 9.2E-26 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 153 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 297 305 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 232 241 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 191 200 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 130 142 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 207 226 4.9E-20 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 SUPERFAMILY SSF52343 200 331 5.89E-39 T 06-07-2017 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Pfam PF00970 Oxidoreductase FAD-binding domain 111 198 2.5E-10 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 80 7.1E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26005 548d3dbfaae944872686a177d0badf24 338 Gene3D G3DSA:3.10.20.30 2 88 2.4E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 50 66 7.6E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 90 100 7.6E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 28 44 7.6E-6 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 Gene3D G3DSA:3.40.50.2300 25 156 8.3E-35 T 06-07-2017 CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 Gene3D G3DSA:3.40.50.2300 311 366 8.3E-35 T 06-07-2017 CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 Pfam PF13458 Periplasmic binding protein 27 376 2.9E-65 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 SUPERFAMILY SSF53822 27 388 4.04E-62 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS07265 2a21c4a11be55fe818db5b2edac30f0b 415 Gene3D G3DSA:3.40.50.2300 172 310 3.9E-19 T 06-07-2017 CAL12_RS20955 4cabb569cab0b8eb3b90550855bf5f3a 257 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 35.847 T 06-07-2017 IPR005583 Peroxide stress protein YaaA CAL12_RS20955 4cabb569cab0b8eb3b90550855bf5f3a 257 Pfam PF03883 Protein of unknown function (DUF328) 1 242 5.1E-90 T 06-07-2017 IPR005583 Peroxide stress protein YaaA CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Gene3D G3DSA:2.30.38.10 363 452 7.3E-23 T 06-07-2017 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Gene3D G3DSA:3.40.50.980 204 351 1.1E-33 T 06-07-2017 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 SUPERFAMILY SSF56801 12 562 4.32E-132 T 06-07-2017 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Gene3D G3DSA:3.30.300.30 461 562 7.4E-26 T 06-07-2017 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Pfam PF00501 AMP-binding enzyme 24 463 6.3E-87 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 542 1.3E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Gene3D G3DSA:3.40.50.980 13 126 2.2E-35 T 06-07-2017 CAL12_RS14040 4cad42e6ed74d9f2c1b9aa3135f00acd 573 Gene3D G3DSA:3.40.50.980 181 203 2.2E-35 T 06-07-2017 CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 SUPERFAMILY SSF52540 4 240 1.69E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 Gene3D G3DSA:3.40.50.300 3 230 1.9E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 Pfam PF00005 ABC transporter 21 158 3.7E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 SMART SM00382 27 207 1.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 Gene3D G3DSA:2.40.50.140 279 336 8.0E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS16355 d7f7a3d7bd33ef1d3f280434c2cc6e34 367 SUPERFAMILY SSF50331 234 348 1.9E-19 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 Gene3D G3DSA:3.40.50.300 3 234 2.2E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 Pfam PF00005 ABC transporter 20 161 1.1E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 SMART SM00382 28 211 5.7E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 SUPERFAMILY SSF52540 4 243 1.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 Gene3D G3DSA:2.40.50.100 238 289 1.7E-4 T 06-07-2017 CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 Pfam PF08402 TOBE domain 275 347 1.4E-13 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27160 41ed966afaf2ec599e66fadbc6d0e676 358 SUPERFAMILY SSF50331 238 349 2.55E-14 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS11110 3cd5cc983c91dadbb29e6d1e1e3cb91c 389 SUPERFAMILY SSF51419 25 249 9.29E-37 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS11110 3cd5cc983c91dadbb29e6d1e1e3cb91c 389 Pfam PF14031 Putative serine dehydratase domain 266 372 9.2E-20 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS11110 3cd5cc983c91dadbb29e6d1e1e3cb91c 389 Gene3D G3DSA:3.20.20.10 30 248 7.8E-23 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS11110 3cd5cc983c91dadbb29e6d1e1e3cb91c 389 Pfam PF01168 Alanine racemase, N-terminal domain 25 250 8.4E-34 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS11110 3cd5cc983c91dadbb29e6d1e1e3cb91c 389 SMART SM01119 266 373 3.3E-39 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 SUPERFAMILY SSF48179 161 263 1.19E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 PIRSF PIRSF000103 1 283 6.0E-16 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 Pfam PF09130 Domain of unknown function (DUF1932) 188 257 6.6E-8 T 06-07-2017 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 Gene3D G3DSA:3.40.50.720 1 167 5.0E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 SUPERFAMILY SSF51735 1 158 6.51E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 Gene3D G3DSA:1.10.1040.10 168 262 1.2E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS01165 777f96796dd93fb7c93af291f494b24a 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 124 2.0E-6 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 SUPERFAMILY SSF81340 25 442 2.75E-88 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 Pfam PF00571 CBS domain 525 571 9.5E-5 T 06-07-2017 IPR000644 CBS domain CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 Pfam PF00571 CBS domain 453 509 0.0045 T 06-07-2017 IPR000644 CBS domain CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 PRINTS PR00762 Chloride channel signature 128 147 1.5E-17 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 PRINTS PR00762 Chloride channel signature 370 386 1.5E-17 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 PRINTS PR00762 Chloride channel signature 179 198 1.5E-17 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 PRINTS PR00762 Chloride channel signature 388 407 1.5E-17 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 Gene3D G3DSA:3.10.580.10 453 571 9.4E-12 T 06-07-2017 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 Gene3D G3DSA:1.10.3080.10 27 440 9.4E-69 T 06-07-2017 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 SUPERFAMILY SSF54631 445 571 5.98E-15 T 06-07-2017 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 Pfam PF00654 Voltage gated chloride channel 85 418 2.3E-68 T 06-07-2017 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 SMART SM00116 524 574 6.2E-4 T 06-07-2017 IPR000644 CBS domain CAL12_RS13135 bd39e3eccfd1e846c9058b247991ae37 605 SMART SM00116 460 509 4.1 T 06-07-2017 IPR000644 CBS domain CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.1E-55 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.899 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 SUPERFAMILY SSF54111 1 99 7.98E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 Gene3D G3DSA:3.30.280.10 1 99 9.4E-51 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 PIRSF PIRSF001223 1 100 1.9E-52 T 06-07-2017 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 Pfam PF00547 Urease, gamma subunit 1 99 1.5E-48 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18370 5afecde34982223c991b6fb4a1627f0c 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-42 T 06-07-2017 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 Pfam PF03466 LysR substrate binding domain 90 293 1.3E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.6E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 Gene3D G3DSA:3.40.190.10 178 262 9.1E-22 T 06-07-2017 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 SUPERFAMILY SSF53850 92 297 1.04E-42 T 06-07-2017 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 Gene3D G3DSA:3.40.190.10 92 177 3.1E-18 T 06-07-2017 CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 Gene3D G3DSA:1.10.10.10 2 80 2.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24120 958ea24566d65d682db41e79213725ba 307 SUPERFAMILY SSF46785 1 109 4.08E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 SUPERFAMILY SSF49879 12 101 1.05E-17 T 06-07-2017 IPR008984 SMAD/FHA domain GO:0005515 CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 Gene3D G3DSA:2.60.200.20 9 93 1.4E-18 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 Pfam PF00498 FHA domain 22 86 1.9E-10 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 Gene3D G3DSA:3.30.450.90 219 316 1.2E-34 T 06-07-2017 CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 SUPERFAMILY SSF52540 208 528 5.57E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 Pfam PF00437 Type II/IV secretion system protein 223 498 1.2E-83 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 Gene3D G3DSA:3.40.50.300 322 530 1.6E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09585 f015dc479bc180dc98feef08c9ca5c22 604 SMART SM00240 21 71 2.0E-5 T 06-07-2017 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CAL12_RS16380 e08a3951c618fb1a53d268d42230bef4 148 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 10 138 3.1E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16380 e08a3951c618fb1a53d268d42230bef4 148 Pfam PF01641 SelR domain 12 129 9.9E-50 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16380 e08a3951c618fb1a53d268d42230bef4 148 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 6 130 37.924 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS16380 e08a3951c618fb1a53d268d42230bef4 148 SUPERFAMILY SSF51316 5 143 3.71E-60 T 06-07-2017 IPR011057 Mss4-like CAL12_RS16380 e08a3951c618fb1a53d268d42230bef4 148 Gene3D G3DSA:2.170.150.20 8 145 1.0E-60 T 06-07-2017 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 7.3E-31 T 06-07-2017 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 7.1E-22 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 7.1E-22 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 7.1E-22 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 8.6E-29 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS11970 cd429d9f3355748401c1be0ec29a1ce5 89 PIRSF PIRSF004669 1 89 1.1E-32 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 53 2.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 23 37 2.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 SMART SM00345 5 63 1.6E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 SMART SM00895 73 197 4.4E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 Gene3D G3DSA:1.20.120.530 66 204 1.4E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 Gene3D G3DSA:1.10.10.10 2 64 8.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 Pfam PF07729 FCD domain 73 196 1.1E-27 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 63 3.0E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 SUPERFAMILY SSF46785 2 67 1.27E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08815 cdb0d5625efe078495476322dfbd0132 252 SUPERFAMILY SSF48008 69 203 4.97E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS18130 ca6845bdaa457870f4a16453e0582850 205 Gene3D G3DSA:1.20.1050.10 90 200 2.4E-6 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS18130 ca6845bdaa457870f4a16453e0582850 205 SUPERFAMILY SSF52833 1 102 4.94E-16 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18130 ca6845bdaa457870f4a16453e0582850 205 Gene3D G3DSA:3.40.30.10 1 89 5.0E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18130 ca6845bdaa457870f4a16453e0582850 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 79 1.8E-15 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS18130 ca6845bdaa457870f4a16453e0582850 205 SUPERFAMILY SSF47616 73 200 5.37E-14 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 Gene3D G3DSA:3.40.50.720 4 234 5.3E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 233 3.3E-49 T 06-07-2017 CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 8.3E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 3.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04435 ba3a1c45850b8c0941ccd1fb82b48dd8 237 SUPERFAMILY SSF51735 5 234 1.86E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04275 672ac7e99de34a93e8d328060971d7e8 278 Gene3D G3DSA:1.10.3720.10 81 267 1.4E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04275 672ac7e99de34a93e8d328060971d7e8 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 257 7.1E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04275 672ac7e99de34a93e8d328060971d7e8 278 SUPERFAMILY SSF161098 80 257 2.88E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00050 4e18f7069a58540e2561df1b22c4f92b 288 SUPERFAMILY SSF54637 73 152 2.83E-7 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00050 4e18f7069a58540e2561df1b22c4f92b 288 SUPERFAMILY SSF54637 172 287 1.03E-17 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00050 4e18f7069a58540e2561df1b22c4f92b 288 Gene3D G3DSA:3.10.129.10 156 272 7.6E-11 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00050 4e18f7069a58540e2561df1b22c4f92b 288 Pfam PF13452 N-terminal half of MaoC dehydratase 73 129 2.0E-9 T 06-07-2017 CAL12_RS12800 e4b6b7f044036a44139fe3c92168245b 389 SUPERFAMILY SSF89796 4 378 2.88E-135 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS12800 e4b6b7f044036a44139fe3c92168245b 389 Gene3D G3DSA:3.30.1540.10 221 303 3.3E-32 T 06-07-2017 CAL12_RS12800 e4b6b7f044036a44139fe3c92168245b 389 Pfam PF02515 CoA-transferase family III 5 371 9.3E-130 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS12800 e4b6b7f044036a44139fe3c92168245b 389 Gene3D G3DSA:3.40.50.10540 304 379 2.7E-112 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS12800 e4b6b7f044036a44139fe3c92168245b 389 Gene3D G3DSA:3.40.50.10540 3 215 2.7E-112 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 Pfam PF03466 LysR substrate binding domain 95 292 5.1E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 Gene3D G3DSA:3.40.190.10 179 263 1.3E-18 T 06-07-2017 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.4E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 SUPERFAMILY SSF53850 96 295 1.36E-26 T 06-07-2017 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 Gene3D G3DSA:1.10.10.10 7 88 2.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 9.6E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 SUPERFAMILY SSF46785 5 84 2.79E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01940 be55825e9336053edbdd2842f4f15ee8 304 Gene3D G3DSA:3.40.190.10 96 178 3.6E-18 T 06-07-2017 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 Gene3D G3DSA:3.40.190.10 97 184 2.9E-16 T 06-07-2017 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 Pfam PF03466 LysR substrate binding domain 96 296 8.9E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 SUPERFAMILY SSF53850 96 303 1.63E-37 T 06-07-2017 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.7E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 Gene3D G3DSA:1.10.10.10 5 86 7.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 SUPERFAMILY SSF46785 6 118 1.82E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 69 1.9E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10635 c98e0cef91f6a1fe28d604692e7baaf1 315 Gene3D G3DSA:3.40.190.10 185 266 7.0E-17 T 06-07-2017 CAL12_RS18040 841c4d037e0c6f4d1ecce3515ce7eead 251 Pfam PF10707 PhoP regulatory network protein YrbL 35 236 3.6E-59 T 06-07-2017 IPR019647 PhoP regulatory network protein YrbL CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Gene3D G3DSA:2.60.120.10 214 301 6.7E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Gene3D G3DSA:2.160.10.10 5 154 2.6E-41 T 06-07-2017 CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Pfam PF05523 WxcM-like, C-terminal 185 310 3.7E-50 T 06-07-2017 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 SUPERFAMILY SSF51182 186 311 3.61E-37 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 SUPERFAMILY SSF51161 14 154 1.34E-39 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 101 135 1.7E-4 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 84 7.3E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS26945 c2a9a4e286aeb86ee083d05a1e2aad2e 317 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 48 7.7E-7 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 SUPERFAMILY SSF68923 13 248 2.09E-103 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 Gene3D G3DSA:3.90.228.20 249 320 9.8E-31 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 Gene3D G3DSA:3.90.228.20 344 616 2.3E-95 T 06-07-2017 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 Gene3D G3DSA:3.40.449.10 15 248 1.8E-101 T 06-07-2017 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 Pfam PF00821 Phosphoenolpyruvate carboxykinase 25 616 2.7E-283 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 PIRSF PIRSF001348 7 618 5.2E-283 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 06-07-2017 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 SUPERFAMILY SSF53795 249 616 1.95E-155 T 06-07-2017 CAL12_RS10995 a8a02e02eab348547c4663a00c8dcda6 618 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 617 51.757 T 06-07-2017 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 407 7.2E-69 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 SUPERFAMILY SSF103473 9 191 1.83E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 SUPERFAMILY SSF103473 243 445 1.83E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 395 414 5.3E-9 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 5.3E-9 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 5.3E-9 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 5.3E-9 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 330 350 5.3E-9 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 Pfam PF07690 Major Facilitator Superfamily 15 404 9.5E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 Gene3D G3DSA:1.20.1250.20 9 190 6.9E-29 T 06-07-2017 CAL12_RS10330 82bb079c2fa9d3c3b2f2c4dd0d532bd4 462 Gene3D G3DSA:1.20.1250.20 257 445 2.8E-14 T 06-07-2017 CAL12_RS16510 7817646efa22050efb6c3eddad822a01 192 Pfam PF03729 Short repeat of unknown function (DUF308) 80 146 1.9E-6 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 SUPERFAMILY SSF46785 20 154 5.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 Gene3D G3DSA:1.10.10.10 16 154 1.1E-36 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 Pfam PF12802 MarR family 46 104 9.9E-13 T 06-07-2017 CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 SMART SM00347 40 140 7.0E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 5.3E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 5.3E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 5.3E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS14030 3cde458dbce354bfe0138b8a45ec3739 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 5.3E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 SMART SM00862 145 216 6.0E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 Gene3D G3DSA:1.10.10.10 124 216 7.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 SUPERFAMILY SSF52172 1 177 2.42E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 1.4E-20 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 Gene3D G3DSA:3.40.50.2300 1 123 7.2E-35 T 06-07-2017 CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 SMART SM00448 1 112 8.3E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS08955 f7f0fd246164fad600da1d0b339370e9 219 Pfam PF00072 Response regulator receiver domain 3 112 6.2E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 Gene3D G3DSA:3.30.70.360 182 298 8.6E-42 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 SUPERFAMILY SSF55031 184 297 1.15E-31 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 378 4.2E-112 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 Pfam PF07687 Peptidase dimerisation domain 186 278 2.5E-13 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 Pfam PF01546 Peptidase family M20/M25/M40 74 354 1.9E-35 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 Gene3D G3DSA:3.40.630.10 299 397 5.5E-101 T 06-07-2017 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 Gene3D G3DSA:3.40.630.10 5 179 5.5E-101 T 06-07-2017 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 PIRSF PIRSF005962 2 398 8.0E-131 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 SUPERFAMILY SSF53187 299 395 4.57E-90 T 06-07-2017 CAL12_RS22220 5b0f8901387f7189ebfa1ed1c5f3213e 403 SUPERFAMILY SSF53187 3 198 4.57E-90 T 06-07-2017 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Gene3D G3DSA:3.30.1360.120 150 237 4.1E-50 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Gene3D G3DSA:3.30.1360.120 5 56 4.1E-50 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 360 3.9E-119 T 06-07-2017 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 PIRSF PIRSF006487 1 367 9.7E-79 T 06-07-2017 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 354 6.6E-13 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 SUPERFAMILY SSF103025 4 278 5.83E-88 T 06-07-2017 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Gene3D G3DSA:3.30.70.1400 57 134 5.3E-30 T 06-07-2017 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 360 42.857 T 06-07-2017 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 SUPERFAMILY SSF101790 280 362 9.48E-22 T 06-07-2017 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Gene3D G3DSA:2.40.30.110 285 363 1.3E-24 T 06-07-2017 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CAL12_RS02650 04cad163d9a411a1c2000ca5e3613ed5 367 Pfam PF01571 Aminomethyltransferase folate-binding domain 12 259 1.1E-85 T 06-07-2017 IPR006222 Glycine cleavage T-protein-like, N-terminal CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 SMART SM00464 40 232 1.2E-37 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 SUPERFAMILY SSF54211 626 795 1.29E-50 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 43 231 6.3E-32 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Gene3D G3DSA:3.30.230.10 623 796 2.7E-67 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 TIGRFAM TIGR00763 lon: endopeptidase La 43 795 8.0E-269 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 SMART SM00382 378 524 1.4E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 701 709 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PIRSF PIRSF001174 27 800 1.5E-275 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Hamap MF_01973 Lon protease [lon]. 41 797 64.545 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 SUPERFAMILY SSF88697 43 230 2.31E-36 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Gene3D G3DSA:3.40.50.300 344 531 1.2E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Gene3D G3DSA:1.10.8.60 532 615 2.4E-32 T 06-07-2017 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 601 797 9.2E-79 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 SUPERFAMILY SSF52540 342 587 3.5E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 382 521 1.9E-19 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 386 405 1.1E-51 T 06-07-2017 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 698 717 1.1E-51 T 06-07-2017 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 728 747 1.1E-51 T 06-07-2017 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 751 769 1.1E-51 T 06-07-2017 CAL12_RS08920 aa73ed8d3ceebde03ef864206d3a4dc8 804 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 626 642 1.1E-51 T 06-07-2017 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 2 254 29.217 T 06-07-2017 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 Pfam PF01958 Domain of unknown function DUF108 155 242 3.9E-33 T 06-07-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 SUPERFAMILY SSF55347 111 222 8.5E-30 T 06-07-2017 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 PIRSF PIRSF005227 1 254 8.4E-66 T 06-07-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 2 105 2.9E-12 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 Gene3D G3DSA:3.30.360.10 111 223 9.5E-35 T 06-07-2017 CAL12_RS15675 718c2557122e6aa08e9ba9d227b03ba1 254 SUPERFAMILY SSF51735 1 140 1.81E-10 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 Gene3D G3DSA:3.40.50.720 5 120 8.8E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 SUPERFAMILY SSF51735 109 288 9.05E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 SUPERFAMILY SSF52283 19 134 2.76E-18 T 06-07-2017 CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 31 319 3.7E-15 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 Gene3D G3DSA:3.40.50.720 121 290 3.1E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24055 904e995be10f7ac7c016f9f01bad1078 337 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 287 4.8E-47 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS15120 d901a88b7c10b97ca32d9dc82001dffe 330 PIRSF PIRSF017082 1 330 7.0E-56 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15120 d901a88b7c10b97ca32d9dc82001dffe 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 1.6E-60 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15120 d901a88b7c10b97ca32d9dc82001dffe 330 SUPERFAMILY SSF53850 118 292 1.52E-6 T 06-07-2017 CAL12_RS24155 3d5f0dd04f5cfb9092129071d546a748 309 Gene3D G3DSA:2.120.10.30 45 303 3.1E-59 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS24155 3d5f0dd04f5cfb9092129071d546a748 309 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 47 283 2.3E-36 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS24155 3d5f0dd04f5cfb9092129071d546a748 309 SUPERFAMILY SSF63829 7 301 5.89E-59 T 06-07-2017 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 99 106 - T 06-07-2017 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 ProSitePatterns PS00760 Signal peptidases I lysine active site. 156 168 - T 06-07-2017 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 Pfam PF10502 Signal peptidase, peptidase S26 243 281 2.1E-6 T 06-07-2017 IPR019533 Peptidase S26 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 Gene3D G3DSA:2.170.230.10 164 218 6.3E-6 T 06-07-2017 IPR019766 Peptidase S26A, all-beta subdomain CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 SUPERFAMILY SSF51306 88 290 1.33E-67 T 06-07-2017 IPR015927 Peptidase S24/S26A/S26B/S26C CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 Pfam PF00717 Peptidase S24-like 96 178 2.2E-22 T 06-07-2017 IPR019759 Peptidase S24/S26A/S26B CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 244 263 4.9E-25 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 154 166 4.9E-25 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 90 106 4.9E-25 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 75 284 9.2E-52 T 06-07-2017 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 Gene3D G3DSA:2.10.109.10 244 290 4.2E-55 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAL12_RS08410 20eb1ff3a8a4efbeffe9e3bac66d6d6c 294 Gene3D G3DSA:2.10.109.10 87 163 4.2E-55 T 06-07-2017 IPR028360 Peptidase S24/S26, beta-ribbon domain CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 Gene3D G3DSA:3.40.50.720 4 249 1.6E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 195 0.0013 T 06-07-2017 CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 249 9.8E-61 T 06-07-2017 CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.8E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06710 7aa7c9fffcad0a25ccdfb32332df597c 250 SUPERFAMILY SSF51735 6 249 1.2E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 SMART SM00893 3 182 3.2E-57 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 Pfam PF01012 Electron transfer flavoprotein domain 4 170 3.4E-42 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 SUPERFAMILY SSF52402 4 186 6.98E-59 T 06-07-2017 CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 SUPERFAMILY SSF52467 189 309 4.02E-47 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 Gene3D G3DSA:3.40.50.620 2 181 1.2E-64 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 1.0E-35 T 06-07-2017 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 06-07-2017 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 Gene3D G3DSA:3.40.50.1220 185 309 1.6E-60 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS18865 ea50546361a8fefbb0b370712e6fe739 309 PIRSF PIRSF000089 1 309 2.6E-107 T 06-07-2017 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CAL12_RS00360 2cbf9849222bba6da9529e9fd38109ce 260 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00360 2cbf9849222bba6da9529e9fd38109ce 260 SMART SM00382 46 237 2.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00360 2cbf9849222bba6da9529e9fd38109ce 260 Pfam PF00005 ABC transporter 37 182 6.7E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00360 2cbf9849222bba6da9529e9fd38109ce 260 SUPERFAMILY SSF52540 20 239 3.01E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00360 2cbf9849222bba6da9529e9fd38109ce 260 Gene3D G3DSA:3.40.50.300 19 239 3.6E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 31 182 2.4E-43 T 06-07-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 Pfam PF08282 haloacid dehalogenase-like hydrolase 96 164 4.8E-8 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 PIRSF PIRSF006118 18 191 2.4E-61 T 06-07-2017 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 33 145 2.6E-12 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 SUPERFAMILY SSF56784 28 185 8.4E-40 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01735 2a61056787dd8da2246be0aa7a8fcf5e 201 Gene3D G3DSA:3.40.50.1000 24 186 5.2E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 SUPERFAMILY SSF51621 20 179 9.42E-286 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 SUPERFAMILY SSF51621 212 957 9.42E-286 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 5 957 19.015 T 06-07-2017 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 Gene3D G3DSA:1.20.1440.90 314 439 2.7E-27 T 06-07-2017 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 147 160 1.1E-35 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 781 807 1.1E-35 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 648 677 1.1E-35 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 436 456 1.1E-35 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 604 616 - T 06-07-2017 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 148 159 - T 06-07-2017 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS11145 40b072ea292cdb494e2b810de70621df 957 Pfam PF00311 Phosphoenolpyruvate carboxylase 144 957 1.5E-272 T 06-07-2017 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 CAL12_RS25635 882e51056ddabb440cd01460c103dbb6 259 SUPERFAMILY SSF88713 4 251 2.0E-101 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS25635 882e51056ddabb440cd01460c103dbb6 259 Pfam PF03746 LamB/YcsF family 5 243 3.9E-104 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAL12_RS25635 882e51056ddabb440cd01460c103dbb6 259 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 247 46.98 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PIRSF PIRSF501177 1 451 1.6E-206 T 06-07-2017 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 226 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 339 348 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 381 397 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 405 413 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 311 330 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 246 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 275 284 5.4E-17 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 20 31 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Gene3D G3DSA:3.40.50.80 298 449 1.1E-31 T 06-07-2017 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Gene3D G3DSA:3.30.70.20 14 66 1.7E-16 T 06-07-2017 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Gene3D G3DSA:2.40.30.10 166 296 2.0E-39 T 06-07-2017 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Pfam PF00037 4Fe-4S binding domain 42 64 3.0E-5 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Pfam PF00037 4Fe-4S binding domain 15 36 1.3E-6 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 SUPERFAMILY SSF52343 300 451 5.11E-33 T 06-07-2017 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 PIRSF PIRSF000361 96 451 3.2E-70 T 06-07-2017 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 Pfam PF00175 Oxidoreductase NAD-binding domain 312 418 4.9E-14 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 121 451 2.9E-154 T 06-07-2017 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 SUPERFAMILY SSF54862 12 74 6.17E-18 T 06-07-2017 CAL12_RS05295 4caa1cd0ddd4a1142b6b917e6069364f 451 SUPERFAMILY SSF63380 162 303 3.69E-36 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS07345 809f7fb3bdfeedfa9175e615eb128696 295 SUPERFAMILY SSF103481 40 132 1.7E-9 T 06-07-2017 CAL12_RS07345 809f7fb3bdfeedfa9175e615eb128696 295 Pfam PF00892 EamA-like transporter family 7 130 4.9E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS07345 809f7fb3bdfeedfa9175e615eb128696 295 Pfam PF00892 EamA-like transporter family 141 279 2.9E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS07345 809f7fb3bdfeedfa9175e615eb128696 295 SUPERFAMILY SSF103481 204 285 1.44E-12 T 06-07-2017 CAL12_RS27000 c72ae720e1030307f69dc1c5450ffc2d 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 158 2.0E-68 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAL12_RS27000 c72ae720e1030307f69dc1c5450ffc2d 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 181 6.6E-80 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAL12_RS27000 c72ae720e1030307f69dc1c5450ffc2d 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 179 6.2E-73 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAL12_RS27000 c72ae720e1030307f69dc1c5450ffc2d 185 SUPERFAMILY SSF51182 2 182 2.97E-75 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS27000 c72ae720e1030307f69dc1c5450ffc2d 185 Gene3D G3DSA:2.60.120.10 2 182 1.2E-81 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS21795 b9e2d38b260c4c9a261188caa3af2161 408 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 11 396 2.3E-76 T 06-07-2017 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CAL12_RS21795 b9e2d38b260c4c9a261188caa3af2161 408 SUPERFAMILY SSF103473 4 401 1.57E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS21795 b9e2d38b260c4c9a261188caa3af2161 408 Gene3D G3DSA:1.20.1250.20 217 401 7.1E-10 T 06-07-2017 CAL12_RS21795 b9e2d38b260c4c9a261188caa3af2161 408 Gene3D G3DSA:1.20.1250.20 16 199 1.3E-23 T 06-07-2017 CAL12_RS21795 b9e2d38b260c4c9a261188caa3af2161 408 Pfam PF07690 Major Facilitator Superfamily 17 361 4.6E-39 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 471 635 1.3E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 302 379 1.2E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 132 189 1.2E-24 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 SUPERFAMILY SSF56003 138 786 2.88E-174 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 190 299 9.2E-29 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 160 726 1.6E-157 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 SMART SM01008 32 143 7.7E-18 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.90.1170.50 13 131 8.3E-21 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 138 6.3E-9 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 SUPERFAMILY SSF54665 15 146 8.64E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 381 470 3.6E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS14720 f890a1f24b9303fa10d8aea594c5fc90 795 Gene3D G3DSA:3.30.365.10 641 785 3.6E-63 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 38 54 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 134 156 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 171 200 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 97 121 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 271 297 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 55 76 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PRINTS PR00073 Coprogen oxidase signature 243 270 7.2E-80 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 PIRSF PIRSF000166 2 310 1.4E-122 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 SUPERFAMILY SSF102886 10 309 1.05E-131 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 Pfam PF01218 Coproporphyrinogen III oxidase 18 310 2.2E-126 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 Gene3D G3DSA:3.40.1500.10 12 309 1.8E-128 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 175 199 - T 06-07-2017 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS17875 a447fac1639d167ce3ac1a51c557ba2d 310 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 11 286 53.516 T 06-07-2017 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.9E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 Gene3D G3DSA:3.40.190.10 95 180 2.5E-21 T 06-07-2017 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 Gene3D G3DSA:3.40.190.10 181 262 8.0E-23 T 06-07-2017 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 SUPERFAMILY SSF46785 5 116 2.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 SUPERFAMILY SSF53850 95 296 5.25E-47 T 06-07-2017 CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 Gene3D G3DSA:1.10.10.10 7 89 5.3E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26530 fc2d96b33e66f238997ec83ad949a431 305 Pfam PF03466 LysR substrate binding domain 95 294 4.6E-45 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 PIRSF PIRSF002741 8 524 1.3E-109 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 SUPERFAMILY SSF53850 37 523 2.9E-115 T 06-07-2017 CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 Gene3D G3DSA:3.10.105.10 299 500 2.9E-51 T 06-07-2017 CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 Gene3D G3DSA:3.40.190.10 157 298 8.1E-39 T 06-07-2017 CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 451 2.2E-76 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS23460 bab4428ec6143079cc899c64328f57ac 535 Gene3D G3DSA:3.90.76.10 73 156 6.1E-17 T 06-07-2017 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 167 338 1.6E-47 T 06-07-2017 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 286 301 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 SMART SM00928 448 494 4.1E-17 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 SUPERFAMILY SSF52833 15 93 8.95E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 SUPERFAMILY SSF142019 119 359 1.27E-88 T 06-07-2017 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 Gene3D G3DSA:3.40.30.10 20 88 8.9E-4 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 450 532 2.3E-30 T 06-07-2017 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 SUPERFAMILY SSF140490 445 531 3.66E-28 T 06-07-2017 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 SUPERFAMILY SSF142984 362 443 1.28E-19 T 06-07-2017 CAL12_RS23955 61f85fad8fc7cdb62e7d97f5ded7e985 555 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 461 472 - T 06-07-2017 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS16135 63b5c2eeaf66e4f12c6fce90e6c89f51 383 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 3 326 5.4E-147 T 06-07-2017 IPR026360 Putative exonuclease, DNA ligase-associated CAL12_RS16135 63b5c2eeaf66e4f12c6fce90e6c89f51 383 Gene3D G3DSA:3.60.15.10 25 178 1.1E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS16135 63b5c2eeaf66e4f12c6fce90e6c89f51 383 SUPERFAMILY SSF56281 10 322 3.41E-58 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 Pfam PF01266 FAD dependent oxidoreductase 10 363 4.6E-50 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 SUPERFAMILY SSF54373 217 320 8.24E-8 T 06-07-2017 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 Gene3D G3DSA:3.50.50.60 7 86 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 Gene3D G3DSA:3.50.50.60 141 219 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 Gene3D G3DSA:3.50.50.60 324 383 1.1E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 SUPERFAMILY SSF51905 324 383 1.19E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01205 45c15eec97f63f66890215703e3f5f70 401 SUPERFAMILY SSF51905 9 220 1.19E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 Gene3D G3DSA:3.40.190.10 178 240 2.4E-6 T 06-07-2017 CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 Gene3D G3DSA:3.40.190.10 91 177 5.4E-18 T 06-07-2017 CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 SUPERFAMILY SSF46785 2 87 2.34E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.0E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 Pfam PF03466 LysR substrate binding domain 87 284 8.5E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 Gene3D G3DSA:1.10.10.10 2 83 1.4E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19320 6b4804f03747124dd6c39a6da6bd17e0 308 SUPERFAMILY SSF53850 87 288 9.77E-38 T 06-07-2017 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 28 182 6.5E-63 T 06-07-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Gene3D G3DSA:1.10.287.180 28 100 1.0E-22 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Hamap MF_00105 Transcription elongation factor GreA [greA]. 27 180 26.044 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Pfam PF03449 Transcription elongation factor, N-terminal 29 99 1.5E-23 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 SUPERFAMILY SSF46557 28 102 4.71E-26 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Hamap MF_00930 Transcription elongation factor GreB [greB]. 26 182 50.48 T 06-07-2017 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 SUPERFAMILY SSF54534 106 181 1.01E-19 T 06-07-2017 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 145 161 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 PIRSF PIRSF006092 26 183 1.1E-43 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Gene3D G3DSA:3.10.50.30 105 183 3.5E-27 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 108 181 6.1E-24 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAL12_RS17070 087506099b0d9bbd460e07a2d23c78bc 185 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 42 73 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 1.0E-16 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 Pfam PF01165 Ribosomal protein S21 4 57 7.0E-21 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.94 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.0E-15 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.0E-15 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.0E-15 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.0E-15 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.0E-23 T 06-07-2017 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09285 6d383598a056f513052a39578b6d37ff 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 06-07-2017 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS09810 4e369fd53d366ffea1aafade0bce60e4 302 Gene3D G3DSA:1.10.3720.10 90 294 3.0E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09810 4e369fd53d366ffea1aafade0bce60e4 302 SUPERFAMILY SSF161098 95 282 4.58E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09810 4e369fd53d366ffea1aafade0bce60e4 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 299 4.1E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09810 4e369fd53d366ffea1aafade0bce60e4 302 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 71 1.3E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS10240 f04f5c7577d61ed557d21c69390ed9a3 486 SUPERFAMILY SSF56672 4 222 8.89E-29 T 06-07-2017 CAL12_RS10240 f04f5c7577d61ed557d21c69390ed9a3 486 Pfam PF00817 impB/mucB/samB family 26 145 6.2E-5 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 Pfam PF13458 Periplasmic binding protein 33 372 1.1E-65 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 SUPERFAMILY SSF53822 33 373 1.14E-95 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 56 72 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 96 106 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 286 299 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 338 353 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 34 50 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 263 281 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 75 93 1.8E-35 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS15215 1f4ca46d958e496bc8f22e04aa17cc2e 378 Gene3D G3DSA:3.40.50.2300 33 233 4.0E-67 T 06-07-2017 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SMART SM00387 253 364 7.3E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SMART SM00388 145 210 3.6E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SUPERFAMILY SSF55874 199 362 5.5E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Gene3D G3DSA:3.30.565.10 196 363 4.6E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 209 9.6E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SMART SM00448 5 119 1.4E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SUPERFAMILY SSF47384 132 210 3.34E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 308 318 2.1E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 361 2.1E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 2.1E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 254 362 6.5E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Pfam PF00072 Response regulator receiver domain 7 120 2.0E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Gene3D G3DSA:3.40.50.2300 3 130 2.9E-31 T 06-07-2017 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 Gene3D G3DSA:1.10.287.130 136 195 8.4E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS22775 3bec287e86dfb0e5254c663ac8cefdf1 369 SUPERFAMILY SSF52172 4 144 1.37E-32 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 Gene3D G3DSA:3.50.50.60 262 326 1.9E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 Gene3D G3DSA:3.50.50.60 4 112 1.9E-28 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 SUPERFAMILY SSF51905 2 320 7.78E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 1.2E-11 T 06-07-2017 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.2E-11 T 06-07-2017 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-11 T 06-07-2017 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PIRSF PIRSF037495 1 466 5.6E-163 T 06-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 Pfam PF04324 BFD-like [2Fe-2S] binding domain 378 430 1.9E-12 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 Gene3D G3DSA:3.50.50.60 113 173 1.3E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 318 4.6E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.2E-8 T 06-07-2017 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 4.2E-8 T 06-07-2017 CAL12_RS15070 7caf93e1c8700251bf20d2dd7d769205 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 4.2E-8 T 06-07-2017 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 55 3.3E-15 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.445 T 06-07-2017 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 SMART SM01409 8 59 6.8E-12 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 SUPERFAMILY SSF63562 1 62 3.66E-18 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 Gene3D G3DSA:3.90.940.10 1 57 2.1E-9 T 06-07-2017 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAL12_RS15435 c6961b58a0d6c81388e13d7804a02d9f 67 Pfam PF01192 RNA polymerase Rpb6 8 56 3.6E-13 T 06-07-2017 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 Gene3D G3DSA:3.20.20.120 134 365 2.1E-66 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 127 4.4E-16 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 Gene3D G3DSA:3.30.390.10 1 133 1.2E-33 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 SUPERFAMILY SSF51604 115 365 1.3E-67 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 Pfam PF13378 Enolase C-terminal domain-like 152 361 6.4E-63 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 SMART SM00922 148 246 1.1E-21 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 SUPERFAMILY SSF54826 1 131 5.3E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS24160 1e7079a0c62769145285389c2f429fce 368 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 195 226 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS02120 70116abd8ece91153a1d10d0a0663444 144 Gene3D G3DSA:2.60.120.10 7 142 8.8E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS02120 70116abd8ece91153a1d10d0a0663444 144 Pfam PF07883 Cupin domain 33 103 6.9E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS02120 70116abd8ece91153a1d10d0a0663444 144 SUPERFAMILY SSF51182 10 112 3.2E-27 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03355 527806d49064bf49972e3ececb2ebd0c 424 SUPERFAMILY SSF103473 8 409 1.44E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03355 527806d49064bf49972e3ececb2ebd0c 424 Gene3D G3DSA:1.20.1250.20 229 407 3.2E-10 T 06-07-2017 CAL12_RS03355 527806d49064bf49972e3ececb2ebd0c 424 Gene3D G3DSA:1.20.1250.20 12 190 4.7E-7 T 06-07-2017 CAL12_RS03355 527806d49064bf49972e3ececb2ebd0c 424 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 18 404 8.5E-86 T 06-07-2017 IPR010645 Uncharacterised MFS-type transporter YbfB CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 SMART SM00387 384 493 9.1E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 490 3.4E-16 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 Gene3D G3DSA:1.10.287.130 277 337 5.8E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 SMART SM00388 278 342 4.1E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 278 337 1.4E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 SUPERFAMILY SSF55874 346 490 2.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 439 1.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 472 1.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 453 1.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 490 1.9E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 Gene3D G3DSA:3.30.565.10 341 491 2.0E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03625 de944f4c3201a332131e8bfea585e39b 494 SUPERFAMILY SSF47384 262 338 7.06E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04200 9e923ad534b2dcee1ab5cc8c3e8d0d35 407 TIGRFAM TIGR03916 rSAM_link_UDG: putative DNA modification/repair radical SAM protein 4 402 2.1E-169 T 06-07-2017 IPR023874 DNA modification/repair radical SAM protein, putative CAL12_RS04200 9e923ad534b2dcee1ab5cc8c3e8d0d35 407 Gene3D G3DSA:3.80.30.20 64 293 1.4E-11 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAL12_RS04200 9e923ad534b2dcee1ab5cc8c3e8d0d35 407 SUPERFAMILY SSF47781 303 379 2.08E-10 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS04200 9e923ad534b2dcee1ab5cc8c3e8d0d35 407 SUPERFAMILY SSF102114 43 193 3.4E-13 T 06-07-2017 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 PIRSF PIRSF001365 8 301 1.0E-92 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 Pfam PF00701 Dihydrodipicolinate synthetase family 12 296 2.9E-100 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 Gene3D G3DSA:3.20.20.70 11 301 2.1E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 SMART SM01130 11 299 1.3E-140 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 SUPERFAMILY SSF51569 11 301 8.69E-102 T 06-07-2017 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 297 65.12 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 8.6E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 8.6E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 8.6E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 8.6E-36 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS07395 f2f1a6630f44c49ddbf60293c304bc3d 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 297 8.6E-105 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS14105 df58590c3102f8e80292eb4a1ab66bed 408 SUPERFAMILY SSF111369 61 299 2.62E-64 T 06-07-2017 CAL12_RS14105 df58590c3102f8e80292eb4a1ab66bed 408 Gene3D G3DSA:2.40.50.100 179 211 5.9E-23 T 06-07-2017 CAL12_RS14105 df58590c3102f8e80292eb4a1ab66bed 408 Gene3D G3DSA:2.40.50.100 71 104 5.9E-23 T 06-07-2017 CAL12_RS14105 df58590c3102f8e80292eb4a1ab66bed 408 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 374 5.1E-84 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS14105 df58590c3102f8e80292eb4a1ab66bed 408 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 293 9.0E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SUPERFAMILY SSF51126 977 1216 9.1E-9 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Gene3D G3DSA:2.40.128.130 1640 1919 4.8E-63 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SUPERFAMILY SSF103515 1586 1919 2.09E-65 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF03797 Autotransporter beta-domain 1642 1905 2.1E-53 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SUPERFAMILY SSF51126 600 969 4.08E-12 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1297 1325 2.4E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1360 1392 1.2E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1140 1170 7.6E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 841 872 4.0E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1232 1261 1.2E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Gene3D G3DSA:2.160.20.20 1218 1346 1.3E-12 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SUPERFAMILY SSF51126 1271 1355 3.77E-8 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SMART SM00869 1642 1909 8.4E-48 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1432 1919 2.4E-50 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 SUPERFAMILY SSF51126 1352 1504 2.48E-12 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF12951 Passenger-associated-transport-repeat 1233 1261 1.9E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF12951 Passenger-associated-transport-repeat 1298 1325 3.6E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF12951 Passenger-associated-transport-repeat 1362 1391 0.012 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF12951 Passenger-associated-transport-repeat 841 871 6.8E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15025 2e11f935526c22f35ab966fd1d056e96 1919 Pfam PF12951 Passenger-associated-transport-repeat 1141 1169 4.7E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 06-07-2017 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 SUPERFAMILY SSF55594 1 87 1.13E-27 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 81 5.4E-29 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 06-07-2017 IPR002114 Phosphotransferase system, HPr serine phosphorylation site CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.3E-15 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.3E-15 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.3E-15 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 2.9E-27 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS09770 659bee7ce7eb2e6d69107902ff565e3c 89 Gene3D G3DSA:3.30.1340.10 3 87 1.0E-31 T 06-07-2017 IPR000032 Phosphocarrier protein HPr-like CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 SUPERFAMILY SSF54909 66 149 8.04E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.5E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.5E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.5E-17 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 9.1E-19 T 06-07-2017 CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 Pfam PF01037 Lrp/AsnC ligand binding domain 71 144 2.7E-18 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 SMART SM00344 4 113 2.2E-46 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 SUPERFAMILY SSF46785 3 63 5.33E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 Gene3D G3DSA:3.30.70.920 56 152 2.6E-29 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS10660 da189e7fd1c4914b6ea0d40f40469085 154 Gene3D G3DSA:1.10.10.10 2 55 4.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 SUPERFAMILY SSF56784 74 284 5.7E-47 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 Gene3D G3DSA:1.10.150.210 88 138 6.5E-25 T 06-07-2017 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 79 250 5.0E-31 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 Pfam PF12710 haloacid dehalogenase-like hydrolase 81 248 2.2E-23 T 06-07-2017 CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 Pfam PF13284 Domain of unknown function (DUF4072) 6 53 2.0E-14 T 06-07-2017 IPR025138 Domain of unknown function DUF4072 CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 Gene3D G3DSA:3.40.50.1000 139 270 1.3E-41 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS19620 42ad816b4f0c316cd16d8e23eb4f8711 285 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 72 280 1.5E-66 T 06-07-2017 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 SUPERFAMILY SSF46785 3 112 5.35E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 Gene3D G3DSA:3.40.190.10 177 260 2.9E-7 T 06-07-2017 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 Gene3D G3DSA:3.40.190.10 92 176 2.9E-23 T 06-07-2017 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 Gene3D G3DSA:1.10.10.10 3 84 3.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 Pfam PF03466 LysR substrate binding domain 90 294 8.5E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 SUPERFAMILY SSF53850 90 298 2.35E-40 T 06-07-2017 CAL12_RS20135 444b92078d1f8fe7840d584cea4b73ca 343 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.9E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06600 603092c62e9103f06e8fe9c966facd3f 314 SUPERFAMILY SSF47413 4 67 2.23E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS06600 603092c62e9103f06e8fe9c966facd3f 314 Pfam PF01381 Helix-turn-helix 12 63 5.3E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS06600 603092c62e9103f06e8fe9c966facd3f 314 SMART SM00530 11 65 1.0E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS06600 603092c62e9103f06e8fe9c966facd3f 314 Gene3D G3DSA:1.10.260.40 8 67 1.6E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS06600 603092c62e9103f06e8fe9c966facd3f 314 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 22 48 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS12335 0e35af963b2883a88dd2cebf2cb0990a 424 Gene3D G3DSA:1.20.1250.20 30 210 1.7E-32 T 06-07-2017 CAL12_RS12335 0e35af963b2883a88dd2cebf2cb0990a 424 Gene3D G3DSA:1.20.1250.20 235 406 1.8E-14 T 06-07-2017 CAL12_RS12335 0e35af963b2883a88dd2cebf2cb0990a 424 SUPERFAMILY SSF103473 13 406 4.05E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12335 0e35af963b2883a88dd2cebf2cb0990a 424 Pfam PF07690 Major Facilitator Superfamily 34 254 3.4E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS11000 211157f8bb488cf2fb6b06eff6ebc69e 100 Pfam PF10711 Hypothetical protein (DUF2513) 3 85 3.5E-8 T 06-07-2017 IPR019650 Protein of unknown function DUF2513 CAL12_RS11000 211157f8bb488cf2fb6b06eff6ebc69e 100 Gene3D G3DSA:1.10.10.10 31 80 2.4E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24150 6c8680902e9a518eb5a766e6ecfe8b10 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 217 8.2E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24150 6c8680902e9a518eb5a766e6ecfe8b10 224 SUPERFAMILY SSF161098 19 207 3.66E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24150 6c8680902e9a518eb5a766e6ecfe8b10 224 Gene3D G3DSA:1.10.3720.10 18 219 6.9E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24150 6c8680902e9a518eb5a766e6ecfe8b10 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 116 3.1E-21 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS01905 8d78634e1f51885a6b2340d40c759be6 186 Gene3D G3DSA:1.10.40.40 14 59 9.0E-16 T 06-07-2017 CAL12_RS01905 8d78634e1f51885a6b2340d40c759be6 186 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 1 174 4.0E-28 T 06-07-2017 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 CAL12_RS01905 8d78634e1f51885a6b2340d40c759be6 186 SUPERFAMILY SSF56784 2 175 1.62E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01905 8d78634e1f51885a6b2340d40c759be6 186 Gene3D G3DSA:3.40.50.1000 60 177 4.7E-46 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 SUPERFAMILY SSF46689 262 310 1.68E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 SMART SM00342 226 309 6.3E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 305 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 Gene3D G3DSA:2.60.120.280 68 210 3.1E-4 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 Pfam PF12833 Helix-turn-helix domain 232 308 2.4E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 Gene3D G3DSA:1.10.10.60 263 307 3.5E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 Gene3D G3DSA:1.10.10.60 211 262 1.0E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21635 66a109e80d0fbe0b3873c700a70a7cc9 312 Pfam PF14525 AraC-binding-like domain 19 189 1.2E-22 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS27110 906f3a784076ac1dd97ce81546b3edf6 313 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 28 311 25.643 T 06-07-2017 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CAL12_RS27110 906f3a784076ac1dd97ce81546b3edf6 313 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 90 112 - T 06-07-2017 IPR030470 UbiA prenyltransferase conserved site CAL12_RS27110 906f3a784076ac1dd97ce81546b3edf6 313 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 33 307 2.5E-92 T 06-07-2017 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 CAL12_RS27110 906f3a784076ac1dd97ce81546b3edf6 313 Pfam PF01040 UbiA prenyltransferase family 52 297 6.1E-56 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAL12_RS03680 c013af6b1c54cb8a510c4005272417fa 373 Gene3D G3DSA:3.90.1150.10 266 367 4.2E-17 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS03680 c013af6b1c54cb8a510c4005272417fa 373 SUPERFAMILY SSF53383 20 363 2.99E-70 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS03680 c013af6b1c54cb8a510c4005272417fa 373 Gene3D G3DSA:3.40.640.10 48 265 3.9E-54 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS03680 c013af6b1c54cb8a510c4005272417fa 373 Pfam PF00155 Aminotransferase class I and II 35 360 8.4E-40 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 SUPERFAMILY SSF52540 34 306 1.1E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 307 2.1E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 Pfam PF00005 ABC transporter 26 183 1.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 2.5E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 Gene3D G3DSA:3.40.50.300 5 257 1.1E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 SMART SM00382 34 241 5.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25715 df583531b0ad0e6848abdbacddd05b76 333 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS06200 b9c3031017cbf2daa1aa8f17eff2685f 191 Pfam PF04355 SmpA / OmlA family 41 110 1.9E-23 T 06-07-2017 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 CAL12_RS06200 b9c3031017cbf2daa1aa8f17eff2685f 191 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 10 118 27.264 T 06-07-2017 IPR026592 Outer membrane protein assembly factor BamE CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 8.1E-8 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 Pfam PF01467 Cytidylyltransferase-like 6 169 1.9E-25 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 SUPERFAMILY SSF52374 2 195 2.75E-45 T 06-07-2017 CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 Gene3D G3DSA:3.40.50.620 3 195 9.1E-56 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 195 28.27 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAL12_RS17880 250616755dd086d947e83a1a433f641f 196 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 194 1.7E-44 T 06-07-2017 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAL12_RS21145 31f602cb3a1c2a426080abbfab6f9fad 216 Gene3D G3DSA:1.10.3720.10 10 209 3.8E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21145 31f602cb3a1c2a426080abbfab6f9fad 216 SUPERFAMILY SSF161098 11 207 5.23E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21145 31f602cb3a1c2a426080abbfab6f9fad 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 6.0E-24 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS21145 31f602cb3a1c2a426080abbfab6f9fad 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 212 4.1E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Pfam PF00270 DEAD/DEAH box helicase 293 435 5.9E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 SMART SM00490 509 592 2.9E-21 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Pfam PF17191 RecG wedge domain 27 171 4.8E-13 T 06-07-2017 IPR033454 RecG, wedge domain CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 38 668 6.5E-212 T 06-07-2017 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 SUPERFAMILY SSF50249 26 174 7.71E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 SUPERFAMILY SSF52540 180 457 2.85E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Gene3D G3DSA:3.40.50.300 458 641 3.6E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 SMART SM00487 267 463 5.6E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Gene3D G3DSA:2.40.50.140 52 139 5.9E-20 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 SUPERFAMILY SSF52540 456 657 7.72E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Pfam PF00271 Helicase conserved C-terminal domain 481 591 1.5E-19 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS15240 b72ee481eec6067036ad1745a6c0884d 696 Gene3D G3DSA:3.40.50.300 259 457 6.2E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Gene3D G3DSA:1.10.150.280 846 893 6.8E-6 T 06-07-2017 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Pfam PF14579 Helix-hairpin-helix motif 810 908 1.0E-28 T 06-07-2017 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Pfam PF01336 OB-fold nucleic acid binding domain 1001 1074 2.9E-10 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Gene3D G3DSA:3.20.20.140 12 261 1.2E-21 T 06-07-2017 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Pfam PF02811 PHP domain 14 178 2.8E-46 T 06-07-2017 IPR004013 PHP domain GO:0003824 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 736 1.5E-173 T 06-07-2017 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 12 1035 0.0 T 06-07-2017 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 Gene3D G3DSA:2.40.50.140 988 1077 4.4E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 SMART SM00481 13 80 3.4E-26 T 06-07-2017 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 CAL12_RS17990 18342c1c8f159b737d1c0939e648c41e 1166 SUPERFAMILY SSF89550 12 266 3.66E-12 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAL12_RS01785 19a7407a1b552c5c372306f334909a94 103 SUPERFAMILY SSF141091 1 101 4.58E-39 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01785 19a7407a1b552c5c372306f334909a94 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 9.6E-37 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01785 19a7407a1b552c5c372306f334909a94 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 06-07-2017 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS01785 19a7407a1b552c5c372306f334909a94 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.287 T 06-07-2017 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01785 19a7407a1b552c5c372306f334909a94 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 7.2E-41 T 06-07-2017 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS00810 4de12cf21159b8aaea6fb2d68c741cbd 137 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 10 114 33.216 T 06-07-2017 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAL12_RS00810 4de12cf21159b8aaea6fb2d68c741cbd 137 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 36 110 4.8E-35 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAL12_RS00810 4de12cf21159b8aaea6fb2d68c741cbd 137 SUPERFAMILY SSF141734 9 117 1.44E-47 T 06-07-2017 CAL12_RS00810 4de12cf21159b8aaea6fb2d68c741cbd 137 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 59 113 2.0E-22 T 06-07-2017 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CAL12_RS08785 82da87873f1beec06886cd1e42c5d0fd 78 Pfam PF00830 Ribosomal L28 family 3 62 9.9E-30 T 06-07-2017 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08785 82da87873f1beec06886cd1e42c5d0fd 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 1.1E-29 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS08785 82da87873f1beec06886cd1e42c5d0fd 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.563 T 06-07-2017 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS08785 82da87873f1beec06886cd1e42c5d0fd 78 Gene3D G3DSA:2.30.170.40 2 77 1.2E-39 T 06-07-2017 CAL12_RS08785 82da87873f1beec06886cd1e42c5d0fd 78 SUPERFAMILY SSF143800 1 76 2.55E-33 T 06-07-2017 CAL12_RS16555 ac03d6331fc06fb916d989b57969ecba 161 Gene3D G3DSA:3.10.129.10 30 153 6.7E-30 T 06-07-2017 IPR029069 HotDog domain CAL12_RS16555 ac03d6331fc06fb916d989b57969ecba 161 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 148 1.7E-17 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAL12_RS16555 ac03d6331fc06fb916d989b57969ecba 161 Pfam PF03061 Thioesterase superfamily 67 144 1.3E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS16555 ac03d6331fc06fb916d989b57969ecba 161 SUPERFAMILY SSF54637 31 145 1.07E-23 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 Pfam PF01230 HIT domain 12 111 4.0E-24 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 SUPERFAMILY SSF54197 1 112 1.11E-36 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 PRINTS PR00332 Histidine triad family signature 27 45 1.9E-17 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 PRINTS PR00332 Histidine triad family signature 98 108 1.9E-17 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 PRINTS PR00332 Histidine triad family signature 6 22 1.9E-17 T 06-07-2017 IPR001310 Histidine triad (HIT) protein CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 ProSitePatterns PS00892 HIT domain signature. 91 109 - T 06-07-2017 IPR019808 Histidine triad, conserved site CAL12_RS00800 295c664b787392b42b51c8ceeb8c1e7f 122 Gene3D G3DSA:3.30.428.10 2 112 1.1E-36 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS26195 c60eb555f5f1c4aab8cdf7f8fe200a32 116 SUPERFAMILY SSF52821 10 114 1.83E-30 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS26195 c60eb555f5f1c4aab8cdf7f8fe200a32 116 Gene3D G3DSA:3.40.250.10 16 114 1.4E-29 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS26195 c60eb555f5f1c4aab8cdf7f8fe200a32 116 Pfam PF00581 Rhodanese-like domain 20 107 1.9E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS26195 c60eb555f5f1c4aab8cdf7f8fe200a32 116 SMART SM00450 16 111 1.2E-25 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 1.8E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 Gene3D G3DSA:1.10.287.130 140 209 1.8E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 SMART SM00388 148 213 5.0E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 SMART SM00387 260 368 1.9E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 Gene3D G3DSA:3.30.565.10 221 368 1.6E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 SUPERFAMILY SSF55874 203 365 1.83E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 211 3.7E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 SUPERFAMILY SSF47384 131 212 2.75E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS17540 6594f3e6a71afadd3842a2076e913512 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 261 365 1.3E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.7E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 Gene3D G3DSA:3.40.190.10 84 195 5.7E-22 T 06-07-2017 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 Pfam PF03466 LysR substrate binding domain 89 287 2.7E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 SUPERFAMILY SSF53850 88 290 7.48E-36 T 06-07-2017 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 7.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 SUPERFAMILY SSF46785 4 113 1.09E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 Gene3D G3DSA:1.10.10.10 3 83 1.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22900 f369953a321d135a1a313adb00867ca5 314 Gene3D G3DSA:3.40.190.10 196 258 3.9E-13 T 06-07-2017 CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 Pfam PF00248 Aldo/keto reductase family 19 268 5.0E-54 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 Gene3D G3DSA:3.20.20.100 12 270 1.4E-80 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 SUPERFAMILY SSF51430 8 271 8.51E-80 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 PRINTS PR00069 Aldo-keto reductase signature 43 67 2.0E-15 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 PRINTS PR00069 Aldo-keto reductase signature 99 117 2.0E-15 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 PRINTS PR00069 Aldo-keto reductase signature 203 227 2.0E-15 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS10785 3ddd51064bbd094ec02939bf90d2722c 281 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.0E-15 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS15935 a0fe8429829576d5eda591a118f734a2 96 Gene3D G3DSA:3.30.1360.20 10 93 3.8E-31 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAL12_RS15935 a0fe8429829576d5eda591a118f734a2 96 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 94 22.449 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAL12_RS15935 a0fe8429829576d5eda591a118f734a2 96 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 12 91 3.0E-27 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAL12_RS15935 a0fe8429829576d5eda591a118f734a2 96 SUPERFAMILY SSF55248 11 93 1.7E-29 T 06-07-2017 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82866 840 1035 9.16E-45 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82714 731 817 8.76E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:3.30.70.1430 579 680 2.2E-25 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Pfam PF00873 AcrB/AcrD/AcrF family 3 1035 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 41 134 1.92E-26 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:1.10.3850.10 285 500 1.0E-62 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:1.10.3850.10 824 1036 1.1E-56 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:3.30.2090.10 731 819 4.6E-24 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:3.30.2090.10 184 278 2.1E-26 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1043 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 575 680 1.47E-24 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82714 185 274 5.23E-21 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.8E-87 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 277 333 1.08E-27 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 139 184 1.08E-27 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 681 730 5.23E-29 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82693 817 866 5.23E-29 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 SUPERFAMILY SSF82866 299 499 2.49E-53 T 06-07-2017 CAL12_RS14110 b34c7cf0b16fcf0c2b724da5cb20e9e4 1079 Gene3D G3DSA:3.30.70.1430 41 140 6.9E-32 T 06-07-2017 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 440 6.9E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 8.3E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 397 8.3E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 8.3E-9 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 223 286 2.3E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 SUPERFAMILY SSF55874 276 440 6.68E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 Gene3D G3DSA:3.30.565.10 294 441 1.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 Pfam PF08521 Two-component sensor kinase N-terminal 22 144 1.6E-4 T 06-07-2017 IPR013727 Two-component sensor kinase, N-terminal CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 SMART SM00388 222 287 1.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 SMART SM00387 332 442 1.8E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 SUPERFAMILY SSF47384 205 286 3.73E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS08950 31acfcdd4d32539ed63be5d2ab5f6f3f 444 Gene3D G3DSA:1.10.287.130 214 283 2.5E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS18185 dfba835591bddd4881fb14a8bb586788 276 Pfam PF00494 Squalene/phytoene synthase 5 263 6.3E-63 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAL12_RS18185 dfba835591bddd4881fb14a8bb586788 276 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 1 275 9.6E-112 T 06-07-2017 IPR017827 Squalene synthase HpnC CAL12_RS18185 dfba835591bddd4881fb14a8bb586788 276 Gene3D G3DSA:1.10.600.10 7 274 1.2E-58 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS18185 dfba835591bddd4881fb14a8bb586788 276 SUPERFAMILY SSF48576 4 275 1.87E-68 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS27155 9ee7061a7eaeaf4398469275f4d136f9 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 276 4.3E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27155 9ee7061a7eaeaf4398469275f4d136f9 286 Gene3D G3DSA:1.10.3720.10 18 282 1.0E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27155 9ee7061a7eaeaf4398469275f4d136f9 286 SUPERFAMILY SSF161098 13 282 4.32E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 Pfam PF00107 Zinc-binding dehydrogenase 181 298 9.9E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 SUPERFAMILY SSF51735 150 298 4.28E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 SMART SM00829 9 339 0.0051 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 Gene3D G3DSA:3.40.50.720 173 288 7.2E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 140 1.1E-29 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 Gene3D G3DSA:3.90.180.10 4 172 6.1E-45 T 06-07-2017 IPR011032 GroES-like CAL12_RS03010 6b3df91c78874d2c9ed3351489ad5084 342 SUPERFAMILY SSF50129 4 178 2.52E-47 T 06-07-2017 IPR011032 GroES-like CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 Gene3D G3DSA:3.20.20.100 1 320 7.7E-82 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 PRINTS PR00069 Aldo-keto reductase signature 47 71 4.6E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 PRINTS PR00069 Aldo-keto reductase signature 111 129 4.6E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 PRINTS PR00069 Aldo-keto reductase signature 142 159 4.6E-6 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 Pfam PF00248 Aldo/keto reductase family 25 317 1.3E-64 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS20765 bd8be2f34c916abd5a7b8918e252b770 355 SUPERFAMILY SSF51430 1 320 1.57E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS04795 b36e3a3c0ffb824224d99c778dd4d250 437 Pfam PF00155 Aminotransferase class I and II 40 405 4.9E-52 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS04795 b36e3a3c0ffb824224d99c778dd4d250 437 SUPERFAMILY SSF53383 11 412 6.46E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS04795 b36e3a3c0ffb824224d99c778dd4d250 437 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 3 412 45.512 T 06-07-2017 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 CAL12_RS04795 b36e3a3c0ffb824224d99c778dd4d250 437 Gene3D G3DSA:3.40.640.10 58 276 3.1E-76 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS04795 b36e3a3c0ffb824224d99c778dd4d250 437 Gene3D G3DSA:3.90.1150.10 277 408 3.3E-23 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 Gene3D G3DSA:3.90.76.10 43 194 4.2E-43 T 06-07-2017 CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 SUPERFAMILY SSF53850 31 498 1.07E-112 T 06-07-2017 CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 Gene3D G3DSA:3.10.105.10 296 486 1.6E-36 T 06-07-2017 CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 PIRSF PIRSF002741 12 505 3.6E-90 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 431 5.5E-78 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS13435 c56cc1cbce48e21994afeea0174da5bd 522 Gene3D G3DSA:3.40.190.10 195 295 2.5E-33 T 06-07-2017 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 78 1.7E-29 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 SUPERFAMILY SSF54364 7 79 3.53E-29 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 06-07-2017 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 31.657 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 2.6E-70 T 06-07-2017 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 169 2.5E-39 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 Gene3D G3DSA:3.10.20.80 5 79 2.9E-34 T 06-07-2017 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 Gene3D G3DSA:3.30.110.10 81 172 4.7E-42 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAL12_RS09755 607cb270d2524546571a3f1eb601aeca 182 SUPERFAMILY SSF55200 84 172 6.02E-35 T 06-07-2017 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Pfam PF00005 ABC transporter 37 195 6.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Pfam PF00005 ABC transporter 315 463 4.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Gene3D G3DSA:3.40.50.300 15 269 5.8E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Gene3D G3DSA:3.40.50.300 288 537 8.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 515 549 8.7E-7 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 279 2.1E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 SUPERFAMILY SSF52540 16 267 4.58E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 SMART SM00382 45 245 1.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 SMART SM00382 323 513 1.0E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03160 477efbee9f743710d333c64d84d8a21e 560 SUPERFAMILY SSF52540 288 535 2.95E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11560 b7618d7f6fe841198e78341c1b86569e 227 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 68 179 5.9E-14 T 06-07-2017 IPR010319 Transglutaminase-like cysteine peptidase, predicted CAL12_RS26030 799e3751f03da0e8d534102763f4dc9a 100 SUPERFAMILY SSF54292 4 95 4.19E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26030 799e3751f03da0e8d534102763f4dc9a 100 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 87 9.7E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS26030 799e3751f03da0e8d534102763f4dc9a 100 Gene3D G3DSA:3.10.20.30 4 95 7.7E-19 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS26030 799e3751f03da0e8d534102763f4dc9a 100 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 Pfam PF01966 HD domain 68 202 3.8E-14 T 06-07-2017 IPR006674 HD domain CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 8 374 37.37 T 06-07-2017 IPR023023 Deoxyguanosinetriphosphate triphosphohydrolase, type 2 CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 SUPERFAMILY SSF109604 21 376 1.92E-88 T 06-07-2017 CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 SMART SM00471 64 212 1.2E-10 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 Pfam PF13286 Phosphohydrolase-associated domain 288 372 4.8E-29 T 06-07-2017 IPR026875 Phosphohydrolase-associated domain CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 Gene3D G3DSA:1.10.3210.10 27 221 1.5E-81 T 06-07-2017 IPR006674 HD domain CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 Gene3D G3DSA:1.10.3210.10 278 375 1.5E-81 T 06-07-2017 IPR006674 HD domain CAL12_RS27420 c8baf9d3de1efc1d65600bdd9f216883 378 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 30 374 5.5E-86 T 06-07-2017 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 141 171 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 44 65 3.9E-17 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 3.9E-17 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 136 153 3.9E-17 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 3.9E-17 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 47 64 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 SUPERFAMILY SSF51569 8 292 7.54E-76 T 06-07-2017 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 19 290 9.5E-66 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 PIRSF PIRSF001365 7 301 5.8E-68 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 291 40.176 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 Pfam PF00701 Dihydrodipicolinate synthetase family 12 289 1.6E-61 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 SMART SM01130 11 293 7.2E-87 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS21660 0ad870d03f6571f483383c494ac7d5ff 317 Gene3D G3DSA:3.20.20.70 10 292 1.5E-84 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 Gene3D G3DSA:3.40.50.2300 27 228 2.6E-62 T 06-07-2017 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 Pfam PF13458 Periplasmic binding protein 28 366 7.5E-58 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 3.7E-32 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS12265 8619561c0cf784e5967885290e72a1b0 371 SUPERFAMILY SSF53822 27 367 2.8E-88 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS20410 232b79caa6502586394f630945db1356 119 SUPERFAMILY SSF52172 1 111 3.42E-19 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS20410 232b79caa6502586394f630945db1356 119 SMART SM00448 1 104 3.1E-5 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS20410 232b79caa6502586394f630945db1356 119 Gene3D G3DSA:3.40.50.2300 1 114 3.8E-19 T 06-07-2017 CAL12_RS20410 232b79caa6502586394f630945db1356 119 Pfam PF00072 Response regulator receiver domain 1 81 3.3E-12 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05495 f1b3a248b93d37c36bfd769e9600c721 178 Gene3D G3DSA:3.40.50.850 5 178 1.8E-51 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS05495 f1b3a248b93d37c36bfd769e9600c721 178 Pfam PF00857 Isochorismatase family 10 155 3.4E-21 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS05495 f1b3a248b93d37c36bfd769e9600c721 178 SUPERFAMILY SSF52499 5 178 1.96E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Gene3D G3DSA:4.10.320.10 253 301 3.3E-19 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 SUPERFAMILY SSF51230 3 96 6.64E-23 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Gene3D G3DSA:3.30.559.10 324 557 1.5E-84 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Pfam PF02817 e3 binding domain 256 291 7.3E-15 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 101 559 4.0E-195 T 06-07-2017 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 334 558 1.1E-80 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 SUPERFAMILY SSF47005 251 296 1.44E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 146 175 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 SUPERFAMILY SSF51230 124 215 3.4E-22 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Gene3D G3DSA:2.40.50.100 123 215 1.3E-20 T 06-07-2017 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Gene3D G3DSA:2.40.50.100 2 97 2.3E-21 T 06-07-2017 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 SUPERFAMILY SSF52777 322 557 4.14E-85 T 06-07-2017 CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Pfam PF00364 Biotin-requiring enzyme 124 194 3.4E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS11745 303879f81fd84230e7dca4a8963d453a 559 Pfam PF00364 Biotin-requiring enzyme 6 77 3.6E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 SUPERFAMILY SSF50891 3 168 3.51E-57 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 PIRSF PIRSF001467 2 169 7.8E-27 T 06-07-2017 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 41 58 - T 06-07-2017 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 Gene3D G3DSA:2.40.100.10 3 168 5.7E-54 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 1.4E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 46 58 1.4E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 1.4E-12 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAL12_RS07600 275c2e885656aaecdc78013e39de757b 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 167 5.1E-47 T 06-07-2017 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CAL12_RS23225 28e24fdc05de0bfb938204070cc88cbe 139 PIRSF PIRSF004638 2 139 5.7E-25 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS23225 28e24fdc05de0bfb938204070cc88cbe 139 Pfam PF03653 Uncharacterised protein family (UPF0093) 6 139 5.4E-19 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 1.1E-33 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 296 313 1.1E-33 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 335 351 1.1E-33 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 1.1E-33 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Gene3D G3DSA:2.30.40.10 68 136 7.3E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 SUPERFAMILY SSF51338 4 130 6.49E-61 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 SUPERFAMILY SSF51338 422 474 6.49E-61 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 ProSitePatterns PS01120 Urease nickel ligands signature. 128 141 - T 06-07-2017 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Gene3D G3DSA:3.20.20.140 137 429 3.6E-208 T 06-07-2017 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Gene3D G3DSA:3.20.20.140 488 565 3.6E-208 T 06-07-2017 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 SUPERFAMILY SSF51556 131 431 1.92E-194 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 SUPERFAMILY SSF51556 480 567 1.92E-194 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 567 6.0E-291 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 120 1.9E-55 T 06-07-2017 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Pfam PF01979 Amidohydrolase family 126 453 9.2E-78 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 ProSitePatterns PS00145 Urease active site. 318 334 - T 06-07-2017 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18385 2cdd5b8720d1a6def19a3f0fa8599e70 567 Hamap MF_01953 Urease subunit alpha [ureC]. 3 567 56.331 T 06-07-2017 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CAL12_RS18640 7975a635d310c8a34c0b74dce5c7c7b2 466 Pfam PF01554 MatE 249 408 8.8E-21 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS18640 7975a635d310c8a34c0b74dce5c7c7b2 466 Pfam PF01554 MatE 24 184 4.2E-22 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS18640 7975a635d310c8a34c0b74dce5c7c7b2 466 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 413 2.5E-64 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS18640 7975a635d310c8a34c0b74dce5c7c7b2 466 PIRSF PIRSF006603 12 465 9.1E-50 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 4.1E-94 T 06-07-2017 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 Gene3D G3DSA:3.40.50.2300 1 122 1.4E-38 T 06-07-2017 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 SUPERFAMILY SSF52172 1 177 3.42E-42 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 Gene3D G3DSA:1.10.10.10 123 221 1.5E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 Pfam PF00072 Response regulator receiver domain 3 111 2.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 8.5E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 SMART SM00862 144 219 2.5E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS23245 55dc5c244532393c327bebbe6d458241 228 SMART SM00448 1 111 2.8E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11090 63291803d97e61a8c78fa46d397c3af1 265 Pfam PF06276 Ferric iron reductase FhuF-like transporter 81 225 7.1E-13 T 06-07-2017 IPR022770 Ferric iron reductase FhuF domain CAL12_RS11090 63291803d97e61a8c78fa46d397c3af1 265 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 233 252 3.3E-7 T 06-07-2017 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CAL12_RS11090 63291803d97e61a8c78fa46d397c3af1 265 TIGRFAM TIGR03951 Fe_III_red_FhuF: siderophore-iron reductase FhuF 74 252 4.1E-31 T 06-07-2017 IPR008090 Ferric iron reductase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 Gene3D G3DSA:3.40.50.300 310 535 3.2E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 Pfam PF00005 ABC transporter 17 177 5.2E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 Pfam PF00005 ABC transporter 332 463 5.4E-20 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 SMART SM00382 26 222 6.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 SMART SM00382 341 508 2.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 SUPERFAMILY SSF52540 297 517 5.41E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 SUPERFAMILY SSF52540 2 81 3.39E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 SUPERFAMILY SSF52540 118 235 3.39E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 Gene3D G3DSA:3.40.50.300 6 274 2.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 Pfam PF12848 ABC transporter 216 291 2.6E-24 T 06-07-2017 IPR032781 ABC-transporter extension domain CAL12_RS17260 e108abf944ff5aa4f393a89738f2bebf 642 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15685 504fa9b9624431b199022bb099873120 179 SUPERFAMILY SSF51182 57 164 9.37E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS15685 504fa9b9624431b199022bb099873120 179 Pfam PF07883 Cupin domain 77 146 4.2E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS15685 504fa9b9624431b199022bb099873120 179 Gene3D G3DSA:2.60.120.10 34 168 4.3E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 SUPERFAMILY SSF53187 294 375 2.62E-68 T 06-07-2017 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 SUPERFAMILY SSF53187 5 180 2.62E-68 T 06-07-2017 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Pfam PF07687 Peptidase dimerisation domain 177 283 2.5E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Gene3D G3DSA:3.30.70.360 190 290 1.7E-34 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 2.5E-160 T 06-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Pfam PF01546 Peptidase family M20/M25/M40 65 374 1.7E-44 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 51.444 T 06-07-2017 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 SUPERFAMILY SSF55031 181 290 2.69E-30 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Gene3D G3DSA:3.40.630.10 318 376 2.3E-76 T 06-07-2017 CAL12_RS17250 e8b1efe654288e556f776906e2093bd2 379 Gene3D G3DSA:3.40.630.10 5 189 2.3E-76 T 06-07-2017 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 Gene3D G3DSA:3.40.50.2300 3 119 8.1E-6 T 06-07-2017 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 Gene3D G3DSA:1.10.10.10 172 239 1.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07945 91279803a4859f59a025741c95afe718 258 Gene3D G3DSA:1.10.10.10 120 137 1.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07945 91279803a4859f59a025741c95afe718 258 SUPERFAMILY SSF52172 2 121 4.61E-8 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07945 91279803a4859f59a025741c95afe718 258 SUPERFAMILY SSF46894 172 238 9.52E-15 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 181 232 1.3E-8 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 9.6E-7 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS07945 91279803a4859f59a025741c95afe718 258 SMART SM00421 177 234 7.1E-9 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 Gene3D G3DSA:3.10.20.30 14 85 1.7E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 Pfam PF01799 [2Fe-2S] binding domain 84 156 9.9E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 SUPERFAMILY SSF54292 13 89 2.1E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 Gene3D G3DSA:1.10.150.120 86 167 6.0E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS01140 fc9d2cdde630b43a60448ef668dbb145 187 SUPERFAMILY SSF47741 95 163 9.29E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 Pfam PF00005 ABC transporter 17 161 4.0E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 SMART SM00382 26 212 2.7E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 Gene3D G3DSA:3.40.50.300 1 227 6.9E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 PIRSF PIRSF039137 1 233 1.6E-106 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CAL12_RS12285 015cc190a2d010d03d05ebf6bab4d0fe 233 SUPERFAMILY SSF52540 2 231 1.92E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04980 b1271d0c6653126edb214d5b0465bd9e 288 Gene3D G3DSA:1.10.530.10 170 261 1.8E-21 T 06-07-2017 CAL12_RS04980 b1271d0c6653126edb214d5b0465bd9e 288 SUPERFAMILY SSF53955 167 272 5.94E-23 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS04980 b1271d0c6653126edb214d5b0465bd9e 288 Pfam PF01464 Transglycosylase SLT domain 174 255 1.3E-15 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAL12_RS05425 7aaef42075905af2dfbaeee4b7bc6d8c 234 SUPERFAMILY SSF56752 21 222 2.62E-42 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS05425 7aaef42075905af2dfbaeee4b7bc6d8c 234 Pfam PF01063 Amino-transferase class IV 22 222 3.5E-35 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS05425 7aaef42075905af2dfbaeee4b7bc6d8c 234 Gene3D G3DSA:3.20.10.10 110 219 1.2E-31 T 06-07-2017 CAL12_RS05425 7aaef42075905af2dfbaeee4b7bc6d8c 234 Gene3D G3DSA:3.30.470.10 24 71 1.2E-5 T 06-07-2017 CAL12_RS01670 ff6bf53896f3447a9948e7ca6fef1926 201 SUPERFAMILY SSF52980 84 187 2.86E-12 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS01670 ff6bf53896f3447a9948e7ca6fef1926 201 Hamap MF_00048 UPF0102 protein YraN [yraN]. 82 197 19.56 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAL12_RS01670 ff6bf53896f3447a9948e7ca6fef1926 201 Pfam PF02021 Uncharacterised protein family UPF0102 89 183 3.3E-21 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAL12_RS01670 ff6bf53896f3447a9948e7ca6fef1926 201 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 82 197 6.2E-21 T 06-07-2017 IPR003509 Uncharacterised protein family UPF0102 CAL12_RS01670 ff6bf53896f3447a9948e7ca6fef1926 201 Gene3D G3DSA:3.40.1350.10 89 198 1.2E-29 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAL12_RS11810 7d37aabf7381280919534726817a8932 290 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 282 3.7E-118 T 06-07-2017 IPR022522 Flagellar motor stator, MotA CAL12_RS11810 7d37aabf7381280919534726817a8932 290 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 236 4.5E-10 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAL12_RS11810 7d37aabf7381280919534726817a8932 290 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 06-07-2017 IPR000540 Flagellar motor protein MotA, conserved site CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 1.2E-27 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 Gene3D G3DSA:3.40.50.2300 3 125 1.5E-41 T 06-07-2017 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 Gene3D G3DSA:1.10.10.10 129 227 2.1E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 SMART SM00862 150 225 8.4E-29 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 SUPERFAMILY SSF52172 3 126 2.56E-43 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 SUPERFAMILY SSF46894 124 226 1.25E-30 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 SMART SM00448 3 116 4.7E-43 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 Pfam PF00072 Response regulator receiver domain 5 117 2.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS25600 02e633c36857f28ff03312fea44167f5 237 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 1.5E-112 T 06-07-2017 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 85 735 2.4E-171 T 06-07-2017 CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Pfam PF00912 Transglycosylase 76 249 9.3E-63 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 SUPERFAMILY SSF53955 62 271 9.84E-76 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Gene3D G3DSA:1.10.3810.10 76 252 1.4E-73 T 06-07-2017 CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Pfam PF00905 Penicillin binding protein transpeptidase domain 457 706 8.2E-35 T 06-07-2017 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Gene3D G3DSA:2.40.50.140 375 444 1.9E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 SUPERFAMILY SSF56601 231 253 5.82E-110 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 SUPERFAMILY SSF56601 286 337 5.82E-110 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 SUPERFAMILY SSF56601 445 761 5.82E-110 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Pfam PF17092 Penicillin-binding protein OB-like domain 340 447 7.2E-17 T 06-07-2017 IPR031376 Penicillin-binding protein, OB-like domain CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Gene3D G3DSA:3.40.710.10 253 337 1.4E-117 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS10085 e9e0ffd10050c166753cc6cc81fd1606 876 Gene3D G3DSA:3.40.710.10 445 754 1.4E-117 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 197 228 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 133 2.5E-13 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 Pfam PF13378 Enolase C-terminal domain-like 160 365 3.5E-53 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 SUPERFAMILY SSF54826 4 133 1.77E-21 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 SUPERFAMILY SSF51604 136 374 6.68E-60 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 Gene3D G3DSA:3.30.390.10 5 138 2.0E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 SMART SM00922 151 250 6.9E-16 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS22910 4a975e8f4a5081c446ab43273635931e 381 Gene3D G3DSA:3.20.20.120 139 369 3.2E-60 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 Gene3D G3DSA:3.10.20.10 37 122 1.5E-28 T 06-07-2017 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 Gene3D G3DSA:3.40.140.10 136 286 3.9E-48 T 06-07-2017 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 PIRSF PIRSF015626 9 288 3.3E-71 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 32 287 3.3E-60 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 SUPERFAMILY SSF53927 28 286 1.11E-74 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 Pfam PF02634 FdhD/NarQ family 35 286 3.4E-73 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAL12_RS23965 ff91013ef134c249a966ee9f393eedcb 288 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 9 287 34.224 T 06-07-2017 IPR003786 Protein FdhD GO:0016783 CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 SUPERFAMILY SSF52540 297 514 6.55E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 Pfam PF00005 ABC transporter 20 173 1.4E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 Pfam PF00005 ABC transporter 316 463 7.7E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 Gene3D G3DSA:3.40.50.300 296 514 1.3E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 Gene3D G3DSA:3.40.50.300 3 241 1.2E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 222 244 2.4E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 SMART SM00382 323 512 3.2E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 SMART SM00382 28 222 7.2E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10725 49ae56b5e18f5068a9d1dc4e25a40576 525 SUPERFAMILY SSF52540 3 244 2.72E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25965 f447ef4065f4c47b2253ec3e65763c27 264 SMART SM00342 179 259 0.0018 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS25965 f447ef4065f4c47b2253ec3e65763c27 264 Gene3D G3DSA:1.10.10.60 164 214 5.7E-4 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS25965 f447ef4065f4c47b2253ec3e65763c27 264 Pfam PF12833 Helix-turn-helix domain 187 254 1.6E-11 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS10545 5ff7ead9735a77e62d55a249a944b8cc 327 Gene3D G3DSA:3.20.20.100 11 319 1.0E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10545 5ff7ead9735a77e62d55a249a944b8cc 327 SUPERFAMILY SSF51430 10 309 3.54E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10545 5ff7ead9735a77e62d55a249a944b8cc 327 Pfam PF00248 Aldo/keto reductase family 15 304 2.3E-63 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS24425 68a412b6214f10db296960818c1c4fe0 222 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 3.7E-101 T 06-07-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 CAL12_RS24425 68a412b6214f10db296960818c1c4fe0 222 Gene3D G3DSA:3.40.1080.10 3 218 4.5E-77 T 06-07-2017 CAL12_RS24425 68a412b6214f10db296960818c1c4fe0 222 SMART SM00882 6 219 6.8E-66 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS24425 68a412b6214f10db296960818c1c4fe0 222 Pfam PF01144 Coenzyme A transferase 9 218 4.9E-55 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS24425 68a412b6214f10db296960818c1c4fe0 222 SUPERFAMILY SSF100950 2 218 2.7E-70 T 06-07-2017 CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 SMART SM00866 95 237 2.9E-30 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 SMART SM00345 16 75 1.1E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 Gene3D G3DSA:1.10.10.10 10 81 2.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 1.9E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 Pfam PF07702 UTRA domain 99 232 8.3E-33 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 SUPERFAMILY SSF46785 9 79 4.94E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 SUPERFAMILY SSF64288 64 241 2.67E-36 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS01315 7c1a8338967e0a18a14e765492dae006 246 Gene3D G3DSA:3.40.1410.10 98 239 1.4E-38 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS11410 dcc3143fef958a2776d40f7767e3bef3 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 3.0E-34 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS13800 933c107b0669af55e54ec34cf74b8831 262 SUPERFAMILY SSF161098 4 258 9.16E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13800 933c107b0669af55e54ec34cf74b8831 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 250 1.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13800 933c107b0669af55e54ec34cf74b8831 262 Gene3D G3DSA:1.10.3720.10 5 257 1.5E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00260 d510b5d117c593db589bfedefb977af7 474 PIRSF PIRSF016636 1 474 3.1E-139 T 06-07-2017 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CAL12_RS00260 d510b5d117c593db589bfedefb977af7 474 PIRSF PIRSF500217 1 474 4.5E-141 T 06-07-2017 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CAL12_RS00260 d510b5d117c593db589bfedefb977af7 474 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 153 352 3.2E-24 T 06-07-2017 IPR004299 Membrane bound O-acyl transferase, MBOAT CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 SUPERFAMILY SSF81296 31 122 5.2E-17 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 Gene3D G3DSA:2.60.40.10 40 122 1.7E-21 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 PIRSF PIRSF006337 35 615 2.1E-206 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 48 578 1.0E-196 T 06-07-2017 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6902 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 SUPERFAMILY SSF51445 121 534 1.62E-97 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 Pfam PF00128 Alpha amylase, catalytic domain 153 242 8.5E-14 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 Gene3D G3DSA:3.20.20.80 129 458 2.0E-76 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 Gene3D G3DSA:3.20.20.80 493 533 2.0E-76 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 SMART SM00642 121 532 1.7E-11 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16165 80b5f4f00fe6d1ecc8f51dc6979f363c 623 Pfam PF11941 Domain of unknown function (DUF3459) 524 607 3.8E-12 T 06-07-2017 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CAL12_RS06625 99cb09598d7398436654a03427ffeba0 252 TIGRFAM TIGR04498 AbiV_defense: abortive infection protein, AbiV family 33 177 1.2E-30 T 06-07-2017 IPR030987 Abortive infection protein, AbiV family CAL12_RS11155 85d58d2f1c4661c187c67b7a9ae11b77 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 5.7E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11155 85d58d2f1c4661c187c67b7a9ae11b77 324 PIRSF PIRSF017082 1 323 1.5E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11155 85d58d2f1c4661c187c67b7a9ae11b77 324 Gene3D G3DSA:3.40.190.10 123 216 3.7E-4 T 06-07-2017 CAL12_RS11155 85d58d2f1c4661c187c67b7a9ae11b77 324 SUPERFAMILY SSF53850 107 282 1.45E-15 T 06-07-2017 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 SMART SM00354 8 78 1.9E-22 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 Gene3D G3DSA:3.40.50.2300 179 311 2.6E-42 T 06-07-2017 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 Pfam PF13377 Periplasmic binding protein-like domain 176 332 8.8E-35 T 06-07-2017 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 55 6.4E-12 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 SUPERFAMILY SSF53822 66 318 8.17E-66 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 SUPERFAMILY SSF47413 7 66 5.95E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 Gene3D G3DSA:1.10.260.40 10 60 1.0E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00600 32a7260b2012e3f16114a60102427f69 343 Gene3D G3DSA:3.40.50.2300 61 178 1.1E-39 T 06-07-2017 CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 SUPERFAMILY SSF51735 116 285 3.06E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 100 1.0E-12 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 Gene3D G3DSA:3.90.180.10 1 149 1.0E-48 T 06-07-2017 IPR011032 GroES-like CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 Pfam PF13602 Zinc-binding dehydrogenase 186 315 4.6E-24 T 06-07-2017 CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 SMART SM00829 10 316 7.0E-35 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 Gene3D G3DSA:3.40.50.720 150 244 3.9E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS18325 d651e7d33a9c1e4d30e4e5edb40741f9 324 SUPERFAMILY SSF50129 1 148 3.5E-42 T 06-07-2017 IPR011032 GroES-like CAL12_RS12070 9f5d61702866ee6df71e560183746441 127 SUPERFAMILY SSF160214 49 121 9.94E-19 T 06-07-2017 IPR005186 FlaG protein CAL12_RS12070 9f5d61702866ee6df71e560183746441 127 Pfam PF03646 FlaG protein 40 120 9.4E-20 T 06-07-2017 IPR005186 FlaG protein CAL12_RS12070 9f5d61702866ee6df71e560183746441 127 Gene3D G3DSA:3.30.160.170 48 120 4.2E-19 T 06-07-2017 IPR005186 FlaG protein CAL12_RS26300 def165b183e80845732a9f3257d9e790 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 106 6.7E-31 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS26300 def165b183e80845732a9f3257d9e790 216 Gene3D G3DSA:1.10.3720.10 10 212 1.4E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS26300 def165b183e80845732a9f3257d9e790 216 SUPERFAMILY SSF161098 11 197 9.03E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS26300 def165b183e80845732a9f3257d9e790 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 210 1.4E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15085 23def8e453db1afccacc5ff969957fb2 292 SUPERFAMILY SSF161098 82 273 4.84E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15085 23def8e453db1afccacc5ff969957fb2 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 288 5.2E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15085 23def8e453db1afccacc5ff969957fb2 292 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 64 1.6E-11 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS15085 23def8e453db1afccacc5ff969957fb2 292 Gene3D G3DSA:1.10.3720.10 78 285 1.0E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 SUPERFAMILY SSF47413 17 80 3.22E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 SUPERFAMILY SSF51182 61 195 4.31E-25 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 Pfam PF01381 Helix-turn-helix 22 73 1.4E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 Gene3D G3DSA:1.10.260.40 18 121 4.9E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 SMART SM00530 21 76 9.7E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 Gene3D G3DSA:2.60.120.10 122 196 1.1E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS13440 68a8c6ffaff230609b1c19a7ac63ba91 211 Pfam PF07883 Cupin domain 127 195 2.9E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS27275 a73931ed41e003c3531ecc755fc46da8 235 SUPERFAMILY SSF52540 2 233 5.11E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27275 a73931ed41e003c3531ecc755fc46da8 235 Pfam PF00005 ABC transporter 17 162 2.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27275 a73931ed41e003c3531ecc755fc46da8 235 SMART SM00382 26 201 1.3E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27275 a73931ed41e003c3531ecc755fc46da8 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27275 a73931ed41e003c3531ecc755fc46da8 235 Gene3D G3DSA:3.40.50.300 1 231 5.5E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 SUPERFAMILY SSF52540 73 358 1.25E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 SMART SM00490 256 337 2.9E-24 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 Pfam PF00270 DEAD/DEAH box helicase 28 195 9.7E-49 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 Gene3D G3DSA:3.40.50.300 208 369 2.1E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 Gene3D G3DSA:3.40.50.300 5 207 1.8E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 Pfam PF03880 DbpA RNA binding domain 387 457 4.1E-21 T 06-07-2017 IPR005580 DbpA, RNA-binding domain CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 SMART SM00487 23 220 1.3E-60 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS03575 60664c39b32d23237471dda7b00b0e2e 462 Pfam PF00271 Helicase conserved C-terminal domain 231 336 3.0E-23 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS13090 20745350097448d2d0c50c882e86cc6c 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 321 3.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13090 20745350097448d2d0c50c882e86cc6c 325 SUPERFAMILY SSF53850 115 278 2.72E-13 T 06-07-2017 CAL12_RS13090 20745350097448d2d0c50c882e86cc6c 325 PIRSF PIRSF017082 1 325 4.3E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 2.6E-18 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 2.6E-18 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 2.6E-18 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 SUPERFAMILY SSF51230 75 150 1.96E-26 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 107 124 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 Gene3D G3DSA:2.40.50.100 75 150 1.3E-33 T 06-07-2017 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 150 2.0E-54 T 06-07-2017 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CAL12_RS24870 3cc79955c974b56928763bc0bfbd0d50 151 Pfam PF00364 Biotin-requiring enzyme 77 150 2.1E-26 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS15470 d9db93cbb381a84555783d0e9fff50ad 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 111 1.6E-28 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS15470 d9db93cbb381a84555783d0e9fff50ad 219 Gene3D G3DSA:1.10.3720.10 12 217 2.5E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15470 d9db93cbb381a84555783d0e9fff50ad 219 SUPERFAMILY SSF161098 13 202 3.53E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15470 d9db93cbb381a84555783d0e9fff50ad 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 217 1.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Gene3D G3DSA:3.40.50.980 31 201 3.7E-36 T 06-07-2017 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Gene3D G3DSA:3.40.50.980 202 347 2.4E-45 T 06-07-2017 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Gene3D G3DSA:3.30.300.30 441 541 2.0E-28 T 06-07-2017 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 SUPERFAMILY SSF56801 20 539 2.09E-142 T 06-07-2017 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Pfam PF00501 AMP-binding enzyme 31 443 1.5E-99 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Gene3D G3DSA:2.30.38.10 359 437 2.9E-20 T 06-07-2017 CAL12_RS01390 ba47e337132758ba2b2467d07ba993c0 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 530 3.1E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 Gene3D G3DSA:3.30.300.30 376 475 2.0E-10 T 06-07-2017 CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 Gene3D G3DSA:3.40.50.980 176 321 3.9E-12 T 06-07-2017 CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 Gene3D G3DSA:3.10.129.10 504 602 2.1E-13 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 SUPERFAMILY SSF54637 501 601 1.84E-15 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 Gene3D G3DSA:3.40.50.980 67 175 3.2E-4 T 06-07-2017 CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 Pfam PF00501 AMP-binding enzyme 160 329 1.4E-10 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS10185 81ca7aa2108614dbadd6dc69b1095f74 617 SUPERFAMILY SSF56801 55 471 5.49E-49 T 06-07-2017 CAL12_RS05695 ef6ad0fcd40de5e0cff85efd10a7159b 70 Gene3D G3DSA:2.60.260.40 4 64 1.8E-20 T 06-07-2017 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS05695 ef6ad0fcd40de5e0cff85efd10a7159b 70 Pfam PF10276 Zinc-finger domain 22 57 1.3E-8 T 06-07-2017 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS25960 617b693b219e8d784404f281763d3339 244 SUPERFAMILY SSF46785 4 77 2.73E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25960 617b693b219e8d784404f281763d3339 244 SUPERFAMILY SSF48008 80 216 1.83E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25960 617b693b219e8d784404f281763d3339 244 Gene3D G3DSA:1.10.10.10 2 71 6.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25960 617b693b219e8d784404f281763d3339 244 SMART SM00345 15 74 1.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25960 617b693b219e8d784404f281763d3339 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 71 1.9E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25960 617b693b219e8d784404f281763d3339 244 SMART SM00895 83 208 7.1E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS25960 617b693b219e8d784404f281763d3339 244 Gene3D G3DSA:1.20.120.530 77 218 2.0E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS25960 617b693b219e8d784404f281763d3339 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 9.6E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25960 617b693b219e8d784404f281763d3339 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 9.6E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS25960 617b693b219e8d784404f281763d3339 244 Pfam PF07729 FCD domain 83 205 7.1E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01125 662a65b9e26e9788e1a8335ea499d88c 283 Pfam PF00561 alpha/beta hydrolase fold 42 266 1.0E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS01125 662a65b9e26e9788e1a8335ea499d88c 283 SUPERFAMILY SSF53474 17 280 6.16E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS01125 662a65b9e26e9788e1a8335ea499d88c 283 Gene3D G3DSA:3.40.50.1820 19 280 2.3E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Gene3D G3DSA:2.40.110.10 118 213 2.3E-19 T 06-07-2017 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 99 6.7E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 211 7.8E-15 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Gene3D G3DSA:1.10.540.10 1 104 7.7E-16 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 SUPERFAMILY SSF47203 224 371 6.77E-34 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 SUPERFAMILY SSF56645 1 223 6.81E-45 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 366 2.4E-22 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS01400 d581441661d2c3ae0028887b0573a554 383 Gene3D G3DSA:1.20.140.10 214 369 9.6E-34 T 06-07-2017 CAL12_RS02745 f09e312bf3148686d6a0a678704ed811 341 PIRSF PIRSF006470 16 341 8.4E-96 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS02745 f09e312bf3148686d6a0a678704ed811 341 SUPERFAMILY SSF53850 146 285 5.07E-5 T 06-07-2017 CAL12_RS02745 f09e312bf3148686d6a0a678704ed811 341 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 52 298 3.0E-71 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS02745 f09e312bf3148686d6a0a678704ed811 341 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 48 324 1.7E-89 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 Pfam PF13247 4Fe-4S dicluster domain 66 167 2.3E-24 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 Gene3D G3DSA:3.30.70.20 83 131 2.8E-26 T 06-07-2017 CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 SUPERFAMILY SSF54862 1 203 1.15E-68 T 06-07-2017 CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 Gene3D G3DSA:3.30.70.20 1 82 3.0E-16 T 06-07-2017 CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 Gene3D G3DSA:3.30.70.20 132 206 7.7E-18 T 06-07-2017 CAL12_RS12910 ca688c8f3f04f7308b69569b26736753 248 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS10930 0344bf63825f2f210daae600b6555fa3 263 SUPERFAMILY SSF52096 2 219 2.16E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS10930 0344bf63825f2f210daae600b6555fa3 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 221 2.3E-37 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS10930 0344bf63825f2f210daae600b6555fa3 263 Gene3D G3DSA:3.90.226.10 3 219 6.0E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 Gene3D G3DSA:3.40.50.300 1 256 1.5E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 278 4.0E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 SMART SM00382 37 231 1.3E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 Pfam PF00005 ABC transporter 28 183 5.3E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS20080 b9e0420e0c2f9de801a38736665b6aa9 284 SUPERFAMILY SSF52540 1 254 2.2E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15150 c9101023c22f4274dddf13c16a93268f 337 SUPERFAMILY SSF54506 1 334 7.38E-97 T 06-07-2017 CAL12_RS15150 c9101023c22f4274dddf13c16a93268f 337 Gene3D G3DSA:3.10.310.10 1 156 2.6E-59 T 06-07-2017 CAL12_RS15150 c9101023c22f4274dddf13c16a93268f 337 PIRSF PIRSF029792 1 337 2.2E-102 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS15150 c9101023c22f4274dddf13c16a93268f 337 Gene3D G3DSA:3.10.310.10 157 324 7.8E-54 T 06-07-2017 CAL12_RS15150 c9101023c22f4274dddf13c16a93268f 337 Pfam PF05544 Proline racemase 9 334 1.5E-94 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS24600 585974d9c46dbcf97b3fdc3981725f36 351 PIRSF PIRSF017082 19 349 1.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24600 585974d9c46dbcf97b3fdc3981725f36 351 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 345 9.0E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24600 585974d9c46dbcf97b3fdc3981725f36 351 SUPERFAMILY SSF53850 137 314 7.47E-15 T 06-07-2017 CAL12_RS10855 e3fd7305ba7d883c3465c959abb52f1f 111 SUPERFAMILY SSF52833 4 99 1.14E-14 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10855 e3fd7305ba7d883c3465c959abb52f1f 111 Pfam PF00085 Thioredoxin 11 98 7.0E-5 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAL12_RS10855 e3fd7305ba7d883c3465c959abb52f1f 111 Gene3D G3DSA:3.40.30.10 4 99 2.9E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00905 15393c07bb4199963fc50d42558b7b34 212 Pfam PF03922 OmpW family 29 212 5.4E-55 T 06-07-2017 IPR005618 Outer membrane protein, OmpW GO:0019867 CAL12_RS00905 15393c07bb4199963fc50d42558b7b34 212 Gene3D G3DSA:2.40.160.20 28 212 1.5E-62 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS00905 15393c07bb4199963fc50d42558b7b34 212 SUPERFAMILY SSF56925 51 212 3.4E-29 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 1.5E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 Pfam PF07729 FCD domain 88 209 3.6E-23 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 Gene3D G3DSA:1.10.10.10 13 77 8.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 SUPERFAMILY SSF48008 83 217 3.92E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 5.6E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 5.6E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 Gene3D G3DSA:1.20.120.530 81 219 4.2E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 SMART SM00895 88 210 4.0E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 SUPERFAMILY SSF46785 15 82 2.33E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01430 7d224fe0f03f7f82c1d5abcf4df9e7be 236 SMART SM00345 20 78 9.7E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 Gene3D G3DSA:1.10.287.950 297 513 2.8E-49 T 06-07-2017 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 Pfam PF00672 HAMP domain 195 262 6.5E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 SMART SM00304 308 361 83.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 SMART SM00304 214 266 3.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 SUPERFAMILY SSF58104 234 543 1.44E-63 T 06-07-2017 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 177 2.5E-14 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 SMART SM00283 274 542 4.4E-54 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS19050 3e7e1815c1ddc0edd06f9e812cc2b5c8 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 345 541 1.3E-42 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS00880 56e028b6f3fb3038207b75a62cab5e4c 174 Pfam PF02470 MlaD protein 39 116 3.2E-21 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS00880 56e028b6f3fb3038207b75a62cab5e4c 174 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 146 2.6E-59 T 06-07-2017 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 CAL12_RS09910 24b4f6de556a271b120c35e92e94af06 376 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 101 373 1.8E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS09910 24b4f6de556a271b120c35e92e94af06 376 SUPERFAMILY SSF53850 165 331 2.71E-8 T 06-07-2017 CAL12_RS09910 24b4f6de556a271b120c35e92e94af06 376 PIRSF PIRSF017082 49 375 9.4E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 Pfam PF01597 Glycine cleavage H-protein 7 121 1.5E-37 T 06-07-2017 IPR002930 Glycine cleavage system H-protein CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 122 23.995 T 06-07-2017 IPR002930 Glycine cleavage system H-protein CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 SUPERFAMILY SSF51230 3 121 1.7E-38 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 Gene3D G3DSA:2.40.50.100 6 121 3.8E-43 T 06-07-2017 CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 121 1.2E-37 T 06-07-2017 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CAL12_RS02655 5250141a4b82da23a82324e57fe22d0b 122 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAL12_RS21100 4d2fef8f6032d93498a2100d8b2de49b 345 Pfam PF14336 Domain of unknown function (DUF4392) 33 324 7.3E-53 T 06-07-2017 IPR025504 Domain of unknown function DUF4392 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 Gene3D G3DSA:3.40.50.2000 252 335 1.6E-5 T 06-07-2017 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 184 335 1.1E-36 T 06-07-2017 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 354 35.595 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 SUPERFAMILY SSF53756 6 352 1.18E-117 T 06-07-2017 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 Gene3D G3DSA:3.40.50.2000 5 195 1.5E-66 T 06-07-2017 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 144 1.1E-37 T 06-07-2017 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS22410 2e59f6ec77e39a8798622df83ffb579c 366 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 6 349 1.8E-102 T 06-07-2017 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 Gene3D G3DSA:3.30.450.40 77 255 5.3E-29 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 Gene3D G3DSA:1.10.10.10 7 76 4.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 Pfam PF01614 Bacterial transcriptional regulator 130 250 1.1E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 SUPERFAMILY SSF46785 7 78 1.74E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 SUPERFAMILY SSF55781 79 251 2.81E-27 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 Pfam PF09339 IclR helix-turn-helix domain 9 58 1.9E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS06015 2ba566abd35d8efbcb696eeecdde0b0c 268 SMART SM00346 6 96 5.4E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS13565 eddd411ada6e95c1b4e72f2fa9a5e554 434 SUPERFAMILY SSF103473 12 426 3.14E-46 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13565 eddd411ada6e95c1b4e72f2fa9a5e554 434 Gene3D G3DSA:1.20.1250.20 230 421 5.5E-20 T 06-07-2017 CAL12_RS13565 eddd411ada6e95c1b4e72f2fa9a5e554 434 Gene3D G3DSA:1.20.1250.20 24 203 4.8E-17 T 06-07-2017 CAL12_RS13565 eddd411ada6e95c1b4e72f2fa9a5e554 434 TIGRFAM TIGR04259 oxa_formateAnti: oxalate/formate antiporter 24 427 8.3E-120 T 06-07-2017 IPR026355 Oxalate/formate antiporter GO:0005215|GO:0006810|GO:0016021 CAL12_RS13565 eddd411ada6e95c1b4e72f2fa9a5e554 434 Pfam PF07690 Major Facilitator Superfamily 33 279 1.7E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 Pfam PF03466 LysR substrate binding domain 87 287 2.3E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 Gene3D G3DSA:3.40.190.10 91 177 3.0E-23 T 06-07-2017 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 Gene3D G3DSA:1.10.10.10 6 86 6.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 5.5E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 SUPERFAMILY SSF46785 7 110 3.13E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 SUPERFAMILY SSF53850 88 290 4.89E-45 T 06-07-2017 CAL12_RS16920 2977b7ecc091ac7487d7f2daa2587975 300 Gene3D G3DSA:3.40.190.10 178 253 2.1E-5 T 06-07-2017 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Hamap MF_00347 Polyphosphate kinase [ppk]. 8 692 32.171 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 SUPERFAMILY SSF140356 8 112 3.01E-33 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 11 686 6.7E-286 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 SUPERFAMILY SSF143724 114 319 3.34E-61 T 06-07-2017 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 SUPERFAMILY SSF56024 333 502 3.14E-56 T 06-07-2017 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Gene3D G3DSA:3.30.1840.10 113 306 2.7E-65 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Gene3D G3DSA:3.30.870.10 510 689 7.8E-71 T 06-07-2017 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Pfam PF13090 Polyphosphate kinase C-terminal domain 340 686 3.8E-153 T 06-07-2017 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Pfam PF13089 Polyphosphate kinase N-terminal domain 11 116 6.0E-33 T 06-07-2017 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Pfam PF02503 Polyphosphate kinase middle domain 126 324 4.8E-57 T 06-07-2017 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 PIRSF PIRSF015589 1 693 1.1E-262 T 06-07-2017 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 SUPERFAMILY SSF56024 511 687 1.05E-66 T 06-07-2017 CAL12_RS06575 0cffa460761bf69bf71d6209e59fce9d 694 Gene3D G3DSA:3.30.870.10 336 509 5.0E-74 T 06-07-2017 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 Pfam PF00890 FAD binding domain 7 440 1.7E-47 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 Gene3D G3DSA:3.50.50.60 404 467 9.2E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 Gene3D G3DSA:3.50.50.60 4 239 9.2E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 Gene3D G3DSA:3.90.700.10 269 398 8.6E-19 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 SUPERFAMILY SSF56425 258 408 6.28E-22 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 8.8E-5 T 06-07-2017 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 8.8E-5 T 06-07-2017 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 SUPERFAMILY SSF51905 5 236 7.6E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20815 f41f156e680aafcb306382ec1743cc7c 477 SUPERFAMILY SSF51905 402 469 7.6E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 SUPERFAMILY SSF50692 574 724 3.39E-42 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 SUPERFAMILY SSF53706 16 594 1.7E-187 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Gene3D G3DSA:2.40.40.20 599 725 3.9E-42 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Pfam PF01568 Molydopterin dinucleotide binding domain 608 717 3.8E-29 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Gene3D G3DSA:3.40.50.740 341 590 1.2E-84 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Gene3D G3DSA:3.40.50.740 91 154 1.2E-84 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Gene3D G3DSA:2.20.25.90 18 72 1.2E-18 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Pfam PF04324 BFD-like [2Fe-2S] binding domain 861 908 5.5E-9 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 SMART SM00926 19 73 3.1E-14 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Gene3D G3DSA:3.40.228.10 155 340 1.3E-67 T 06-07-2017 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 20 71 1.1E-15 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS07025 4b9bb2a9b6dd12cc4d5c70dca9142f6e 916 Pfam PF00384 Molybdopterin oxidoreductase 97 505 2.2E-77 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 SUPERFAMILY SSF52540 2 249 5.0E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 SMART SM00382 26 225 1.1E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 Gene3D G3DSA:3.40.50.300 1 247 4.0E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 3.8E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 Pfam PF00005 ABC transporter 17 178 5.6E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24760 6ac1ea98e12b86677632769ab9303a53 260 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 Gene3D G3DSA:3.40.50.300 3 232 2.2E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 SMART SM00382 27 210 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 SUPERFAMILY SSF52540 4 239 3.39E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 SUPERFAMILY SSF50331 247 351 2.81E-6 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 Pfam PF08402 TOBE domain 276 347 4.2E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 Pfam PF00005 ABC transporter 20 160 7.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07195 05ff43d9f802cb3897e1eb7247dd2866 356 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS11330 d603ebc2fb40b8b3e7f39b19ec9e8fc1 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 2.0E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS21230 75c2d4fcdb4096b414bf150599937d40 332 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 158 253 2.6E-10 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS21230 75c2d4fcdb4096b414bf150599937d40 332 Gene3D G3DSA:3.40.50.2000 151 278 1.1E-22 T 06-07-2017 CAL12_RS21230 75c2d4fcdb4096b414bf150599937d40 332 SUPERFAMILY SSF53756 12 277 1.02E-23 T 06-07-2017 CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 SMART SM00342 227 297 3.2E-6 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 SUPERFAMILY SSF46689 215 259 2.02E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 Pfam PF12833 Helix-turn-helix domain 233 287 2.5E-11 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 Gene3D G3DSA:1.10.10.60 211 264 2.8E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 Gene3D G3DSA:3.40.50.880 1 210 4.8E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 Pfam PF01965 DJ-1/PfpI family 3 171 5.2E-21 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS06685 a566713191e49df0bcd527b855a55f3a 297 SUPERFAMILY SSF52317 1 192 3.9E-47 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS23665 1310695ce81029e65dbf98d960b0933d 107 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 78 107 1.4E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23665 1310695ce81029e65dbf98d960b0933d 107 Gene3D G3DSA:2.160.20.20 51 106 1.2E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23665 1310695ce81029e65dbf98d960b0933d 107 SUPERFAMILY SSF51126 2 106 4.71E-10 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23665 1310695ce81029e65dbf98d960b0933d 107 Pfam PF12951 Passenger-associated-transport-repeat 79 106 2.7E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23665 1310695ce81029e65dbf98d960b0933d 107 Pfam PF12951 Passenger-associated-transport-repeat 1 22 1.6E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Gene3D G3DSA:1.10.540.10 1 121 9.9E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Gene3D G3DSA:1.20.140.10 222 380 9.5E-58 T 06-07-2017 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Gene3D G3DSA:2.40.110.10 124 221 4.0E-30 T 06-07-2017 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 SUPERFAMILY SSF56645 1 241 3.8E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.7E-46 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 201 4.3E-20 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.4E-19 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS24555 3156671003e46eb83780d197e4fa8384 390 SUPERFAMILY SSF47203 229 380 5.32E-51 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS23140 add6392bf457c40a99833a3dcf88ef16 241 SUPERFAMILY SSF52266 47 240 5.24E-37 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS23140 add6392bf457c40a99833a3dcf88ef16 241 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 87 231 1.0E-15 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS23140 add6392bf457c40a99833a3dcf88ef16 241 Gene3D G3DSA:3.40.50.1110 40 240 2.9E-36 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS04725 afff34aef9e3e394ebec1dbe0ef43325 412 SUPERFAMILY SSF53850 204 372 2.46E-10 T 06-07-2017 CAL12_RS04725 afff34aef9e3e394ebec1dbe0ef43325 412 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 142 408 1.5E-53 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1034 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:3.30.70.1430 38 139 1.8E-31 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.1E-102 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 38 128 4.19E-25 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:3.30.2090.10 723 810 1.5E-19 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:3.30.2090.10 182 275 9.8E-26 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82866 296 497 1.31E-50 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 672 721 2.46E-26 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 808 856 2.46E-26 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 135 182 1.1E-24 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 274 329 1.1E-24 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82714 723 808 3.27E-18 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82866 831 1024 4.19E-43 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:1.10.3850.10 813 1026 1.4E-55 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:1.20.1640.10 294 508 2.1E-57 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 Gene3D G3DSA:3.30.70.1430 568 670 1.9E-30 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82693 566 669 5.75E-26 T 06-07-2017 CAL12_RS21260 89bd7fc22b36569bae31b91fdf7eef2c 1067 SUPERFAMILY SSF82714 182 272 5.23E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SMART SM00878 336 447 4.0E-53 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Gene3D G3DSA:3.30.470.20 203 453 1.5E-104 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 2.7E-40 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Gene3D G3DSA:2.40.50.100 618 686 2.4E-22 T 06-07-2017 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Pfam PF02785 Biotin carboxylase C-terminal domain 336 448 1.1E-34 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Gene3D G3DSA:3.30.1490.20 129 202 9.2E-31 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Gene3D G3DSA:3.40.50.20 3 128 2.4E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 643 660 - T 06-07-2017 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SUPERFAMILY SSF52440 2 113 2.45E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Pfam PF00364 Biotin-requiring enzyme 620 685 1.9E-16 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SUPERFAMILY SSF51230 615 686 8.77E-20 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SMART SM01209 114 293 0.0011 T 06-07-2017 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SUPERFAMILY SSF56059 83 345 9.19E-73 T 06-07-2017 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 SUPERFAMILY SSF51246 331 453 1.62E-38 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00525 61d433066e50e312b7f9dcaddb0004fe 687 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 1.0E-82 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS14470 17b2c8de2c84da5879adf055b3e74be3 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 222 5.0E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14470 17b2c8de2c84da5879adf055b3e74be3 229 Gene3D G3DSA:1.10.3720.10 9 223 2.6E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14470 17b2c8de2c84da5879adf055b3e74be3 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 117 9.4E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS14470 17b2c8de2c84da5879adf055b3e74be3 229 SUPERFAMILY SSF161098 14 223 4.45E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 Gene3D G3DSA:1.10.10.10 8 148 1.9E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04295 e30005f42da902251723e58c821e2114 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 1.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.8E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS04295 e30005f42da902251723e58c821e2114 166 SMART SM00347 33 133 5.5E-15 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 Pfam PF12802 MarR family 39 97 7.1E-15 T 06-07-2017 CAL12_RS04295 e30005f42da902251723e58c821e2114 166 SUPERFAMILY SSF46785 9 148 1.59E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 Gene3D G3DSA:3.90.45.10 5 165 2.0E-64 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 PIRSF PIRSF004749 1 166 8.7E-54 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 Hamap MF_00163 Peptide deformylase [def]. 2 163 30.757 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 161 3.6E-56 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 PRINTS PR01576 Peptide deformylase signature 121 150 1.1E-36 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 PRINTS PR01576 Peptide deformylase signature 90 101 1.1E-36 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 PRINTS PR01576 Peptide deformylase signature 33 62 1.1E-36 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 PRINTS PR01576 Peptide deformylase signature 102 120 1.1E-36 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 Pfam PF01327 Polypeptide deformylase 4 153 1.9E-50 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS26380 4802e4a016261c23ab0123db6d604d2f 167 SUPERFAMILY SSF56420 2 164 1.05E-61 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 SMART SM00865 206 324 8.9E-52 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 SMART SM00864 15 204 2.2E-101 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 SUPERFAMILY SSF55307 206 319 1.21E-39 T 06-07-2017 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 Gene3D G3DSA:3.30.1330.20 215 318 8.8E-44 T 06-07-2017 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 Gene3D G3DSA:3.40.50.1440 16 214 6.6E-82 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 322 2.4E-115 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 343 34.431 T 06-07-2017 IPR000158 Cell division protein FtsZ GO:0005525 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 SUPERFAMILY SSF52490 15 207 1.23E-61 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 PRINTS PR00423 Cell division protein FtsZ signature 125 146 1.0E-45 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 PRINTS PR00423 Cell division protein FtsZ signature 97 117 1.0E-45 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 PRINTS PR00423 Cell division protein FtsZ signature 188 210 1.0E-45 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 PRINTS PR00423 Cell division protein FtsZ signature 211 232 1.0E-45 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 8.4E-36 T 06-07-2017 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CAL12_RS22385 85162d1ea4a29f1c0b3decf94d7e473d 397 Pfam PF12327 FtsZ family, C-terminal domain 221 315 7.5E-31 T 06-07-2017 IPR024757 Cell division protein FtsZ, C-terminal CAL12_RS25505 cf2b5a6bfb991f03b705061bd087914f 218 Gene3D G3DSA:1.10.3720.10 12 214 1.1E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25505 cf2b5a6bfb991f03b705061bd087914f 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 54 214 1.2E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25505 cf2b5a6bfb991f03b705061bd087914f 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 7.5E-26 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS25505 cf2b5a6bfb991f03b705061bd087914f 218 SUPERFAMILY SSF161098 14 205 2.09E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 540 572 0.096 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 272 3.9E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Gene3D G3DSA:3.40.50.300 5 258 1.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Gene3D G3DSA:3.40.50.300 306 562 1.1E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 SUPERFAMILY SSF52540 307 560 7.39E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Pfam PF00005 ABC transporter 335 489 3.2E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 Pfam PF00005 ABC transporter 27 184 8.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 SUPERFAMILY SSF52540 6 256 2.55E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 SMART SM00382 343 546 3.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08115 87d8509acb70e10ab67024df520f02df 578 SMART SM00382 35 234 4.9E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 4.5E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 246 2.8E-62 T 06-07-2017 CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 1.5E-4 T 06-07-2017 CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 Gene3D G3DSA:3.40.50.720 1 246 1.1E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03765 170c9f724134d74eb6628c6830e1b4d5 249 SUPERFAMILY SSF51735 6 246 2.1E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08655 00908107c37f4d06b4daeac80bc6b6f6 160 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.376 T 06-07-2017 IPR023081 Cell division protein FtsB CAL12_RS08655 00908107c37f4d06b4daeac80bc6b6f6 160 Pfam PF04977 Septum formation initiator 12 89 3.7E-24 T 06-07-2017 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 SUPERFAMILY SSF46894 142 212 1.87E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.5E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 Pfam PF00072 Response regulator receiver domain 4 118 1.0E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 Gene3D G3DSA:1.10.10.10 155 212 3.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 Gene3D G3DSA:3.40.50.2300 1 154 1.5E-29 T 06-07-2017 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 2.3E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 SMART SM00448 2 118 1.7E-14 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 SMART SM00421 149 206 4.9E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS22165 27626c2476a418c85bfa08c62f6d9dfc 212 SUPERFAMILY SSF52172 1 133 1.57E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 SUPERFAMILY SSF51556 365 455 1.3E-47 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 SUPERFAMILY SSF51556 107 268 1.3E-47 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 SUPERFAMILY SSF51556 312 336 1.3E-47 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 SUPERFAMILY SSF51338 454 498 5.04E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 SUPERFAMILY SSF51338 34 108 5.04E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Pfam PF01979 Amidohydrolase family 104 239 3.1E-6 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Pfam PF01979 Amidohydrolase family 396 476 1.3E-9 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Gene3D G3DSA:2.30.40.10 454 513 2.5E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Gene3D G3DSA:2.30.40.10 41 109 2.5E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Gene3D G3DSA:3.20.20.140 110 267 2.1E-42 T 06-07-2017 CAL12_RS01375 26ffacc01fc7e7eae50aaad614b686ec 537 Gene3D G3DSA:3.20.20.140 311 452 2.1E-42 T 06-07-2017 CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 289 6.8E-57 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 230 247 2.2E-10 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 272 290 2.2E-10 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 161 183 2.2E-10 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 184 204 2.2E-10 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 Gene3D G3DSA:2.120.10.30 7 306 3.8E-63 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS18500 91cb1b12010310a1ba7f456723e3316c 310 SUPERFAMILY SSF63829 11 298 3.49E-58 T 06-07-2017 CAL12_RS06780 1ffea768d57b95765979e1a29a9afd4c 293 Gene3D G3DSA:3.40.50.1820 19 291 1.3E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS06780 1ffea768d57b95765979e1a29a9afd4c 293 SUPERFAMILY SSF53474 18 290 2.52E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS06780 1ffea768d57b95765979e1a29a9afd4c 293 Pfam PF12697 Alpha/beta hydrolase family 47 282 4.3E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS04180 770243729dc594b3af049259a2168fbb 114 PIRSF PIRSF019302 9 113 3.3E-44 T 06-07-2017 IPR016755 Uncharacterised conserved protein UCP019302 CAL12_RS04180 770243729dc594b3af049259a2168fbb 114 Pfam PF10084 Uncharacterized protein conserved in bacteria (DUF2322) 11 108 8.5E-41 T 06-07-2017 IPR016755 Uncharacterised conserved protein UCP019302 CAL12_RS18135 461705335dace42629ba32a94c987c9d 207 Gene3D G3DSA:1.20.1290.10 35 175 8.7E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS18135 461705335dace42629ba32a94c987c9d 207 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 115 2.1E-5 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS18135 461705335dace42629ba32a94c987c9d 207 SUPERFAMILY SSF69118 1 176 4.58E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Pfam PF16657 Maltogenic Amylase, C-terminal domain 471 548 2.5E-31 T 06-07-2017 IPR032091 Maltogenic Amylase, C-terminal CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:3.90.400.10 116 184 3.9E-25 T 06-07-2017 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 SMART SM00642 24 423 1.9E-95 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 567 1098 8.4E-170 T 06-07-2017 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 16 551 5.8E-280 T 06-07-2017 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:3.20.20.80 450 464 9.8E-107 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:3.20.20.80 18 115 9.8E-107 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:3.20.20.80 192 417 9.8E-107 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 SUPERFAMILY SSF56112 763 1095 2.24E-15 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Pfam PF00128 Alpha amylase, catalytic domain 39 392 1.2E-73 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:2.60.40.1180 471 551 2.6E-22 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 SUPERFAMILY SSF51445 14 334 1.98E-126 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 SUPERFAMILY SSF51445 361 468 1.98E-126 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 SUPERFAMILY SSF51011 475 551 1.32E-20 T 06-07-2017 CAL12_RS16150 a49e225b6cee8a25adc6ba9aa8a1222a 1115 Gene3D G3DSA:3.90.1200.10 849 966 2.6E-7 T 06-07-2017 CAL12_RS07505 40e064f1ffabe119645b06d9eb433f1d 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 317 2.3E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07505 40e064f1ffabe119645b06d9eb433f1d 321 SUPERFAMILY SSF53850 111 281 1.55E-14 T 06-07-2017 CAL12_RS07505 40e064f1ffabe119645b06d9eb433f1d 321 PIRSF PIRSF017082 1 321 2.8E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02195 0d029f14f08042a4f2141521554fd6c4 491 Pfam PF04055 Radical SAM superfamily 110 253 9.1E-9 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS02195 0d029f14f08042a4f2141521554fd6c4 491 Gene3D G3DSA:3.20.20.70 108 438 7.4E-33 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS02195 0d029f14f08042a4f2141521554fd6c4 491 Pfam PF13353 4Fe-4S single cluster domain 104 233 4.0E-7 T 06-07-2017 CAL12_RS02195 0d029f14f08042a4f2141521554fd6c4 491 SUPERFAMILY SSF102114 109 437 2.75E-30 T 06-07-2017 CAL12_RS02195 0d029f14f08042a4f2141521554fd6c4 491 TIGRFAM TIGR03978 rSAM_paired_1: His-Xaa-Ser system radical SAM maturase HxsB 23 487 2.9E-179 T 06-07-2017 IPR024023 His-Xaa-Ser system radical SAM maturase HxsB CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 Pfam PF00106 short chain dehydrogenase 6 188 2.2E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 3.5E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 6.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 6.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 6.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 Gene3D G3DSA:3.40.50.720 5 251 1.0E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18995 af8e70c43ead353e638d28502a00efdc 282 SUPERFAMILY SSF51735 5 249 1.65E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09135 78c3c81426abf7b8d116d0f526c1042e 308 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 213 292 3.0E-20 T 06-07-2017 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal CAL12_RS09135 78c3c81426abf7b8d116d0f526c1042e 308 Pfam PF03524 Conjugal transfer protein 61 147 4.1E-14 T 06-07-2017 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 Pfam PF06850 PHB de-polymerase C-terminus 205 406 2.7E-98 T 06-07-2017 IPR009656 PHB de-polymerase, C-terminal CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 SUPERFAMILY SSF53474 97 404 3.95E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 405 1.8E-191 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 PIRSF PIRSF020818 1 407 3.7E-203 T 06-07-2017 IPR010915 Polyhydroxyalkanoate depolymerase CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 Gene3D G3DSA:3.40.50.1820 255 300 9.8E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 Gene3D G3DSA:3.40.50.1820 332 406 9.8E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS08220 116ac803607de6cf0e16b0419c1e4c8b 407 Gene3D G3DSA:3.40.50.1820 91 219 9.8E-9 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 Gene3D G3DSA:1.20.1250.20 265 449 2.0E-9 T 06-07-2017 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 Gene3D G3DSA:1.20.1250.20 2 188 1.8E-30 T 06-07-2017 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 Pfam PF07690 Major Facilitator Superfamily 5 407 5.0E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 SUPERFAMILY SSF103473 242 449 8.46E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 SUPERFAMILY SSF103473 2 188 8.46E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 4 28 1.5E-7 T 06-07-2017 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 398 417 1.5E-7 T 06-07-2017 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 125 149 1.5E-7 T 06-07-2017 CAL12_RS16680 e77904f6a8b6c4b46af6e8f38581dcbf 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 95 115 1.5E-7 T 06-07-2017 CAL12_RS24495 913a174e5450616b4423141f0a43152c 274 Pfam PF00005 ABC transporter 35 177 1.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24495 913a174e5450616b4423141f0a43152c 274 Gene3D G3DSA:3.40.50.300 13 241 2.2E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24495 913a174e5450616b4423141f0a43152c 274 SUPERFAMILY SSF52540 21 253 4.56E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24495 913a174e5450616b4423141f0a43152c 274 SMART SM00382 44 228 2.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24495 913a174e5450616b4423141f0a43152c 274 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 Pfam PF01614 Bacterial transcriptional regulator 132 251 1.5E-20 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 SMART SM00346 11 99 4.5E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 Gene3D G3DSA:3.30.450.40 83 256 6.4E-40 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 Gene3D G3DSA:1.10.10.10 12 77 3.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 SUPERFAMILY SSF55781 83 256 1.14E-38 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 SUPERFAMILY SSF46785 13 79 2.92E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02445 4a4b9f3d20a878a3bec84fbfd3aed84f 257 Pfam PF09339 IclR helix-turn-helix domain 14 62 5.4E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS00985 4d5257b51f264d2e5ffacc4afba6818c 275 Pfam PF00293 NUDIX domain 136 252 2.2E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS00985 4d5257b51f264d2e5ffacc4afba6818c 275 SUPERFAMILY SSF55811 102 266 5.82E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS00985 4d5257b51f264d2e5ffacc4afba6818c 275 Gene3D G3DSA:3.90.79.10 97 272 2.8E-45 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS08710 db363ab6f296410255cab2c1b8459f41 140 PIRSF PIRSF004638 1 140 7.3E-48 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS08710 db363ab6f296410255cab2c1b8459f41 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 4.0E-43 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 88 397 3.1E-77 T 06-07-2017 IPR011970 Lytic murein transglycosylase CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 SUPERFAMILY SSF53955 80 399 1.24E-67 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 Pfam PF13406 Transglycosylase SLT domain 87 391 1.2E-76 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 Gene3D G3DSA:1.10.101.10 405 470 7.1E-15 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 SUPERFAMILY SSF47090 400 470 6.02E-18 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 Gene3D G3DSA:1.10.530.10 266 398 7.5E-46 T 06-07-2017 CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 Gene3D G3DSA:1.10.530.10 131 186 7.5E-46 T 06-07-2017 CAL12_RS10880 c02f5074392c5e3b7fde46375edeab4d 473 Pfam PF01471 Putative peptidoglycan binding domain 414 469 4.7E-12 T 06-07-2017 IPR002477 Peptidoglycan binding-like CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 SUPERFAMILY SSF46785 13 112 5.44E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 Gene3D G3DSA:1.10.10.10 1 81 5.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 Gene3D G3DSA:3.40.190.10 179 266 9.6E-25 T 06-07-2017 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 Pfam PF03466 LysR substrate binding domain 90 296 4.3E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 SUPERFAMILY SSF53850 92 303 8.2E-38 T 06-07-2017 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 Gene3D G3DSA:3.40.190.10 91 178 1.3E-18 T 06-07-2017 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS08480 798c4cd37ac87bf6ec13cacfedfa587c 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.4E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01005 8ed069eb02fa91860533e1a779dca868 291 Gene3D G3DSA:1.20.120.80 81 290 3.1E-64 T 06-07-2017 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS01005 8ed069eb02fa91860533e1a779dca868 291 Pfam PF00510 Cytochrome c oxidase subunit III 16 291 6.4E-59 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS01005 8ed069eb02fa91860533e1a779dca868 291 SUPERFAMILY SSF81452 12 290 9.42E-80 T 06-07-2017 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS01005 8ed069eb02fa91860533e1a779dca868 291 Gene3D G3DSA:1.10.287.70 11 77 1.1E-14 T 06-07-2017 CAL12_RS24075 8224e1c457c3dcd5d550de848eb6c685 479 Pfam PF07171 MlrC C-terminus 297 471 4.8E-56 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS24075 8224e1c457c3dcd5d550de848eb6c685 479 Pfam PF07364 Metallopeptidase family M81 2 288 3.5E-91 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS24075 8224e1c457c3dcd5d550de848eb6c685 479 PIRSF PIRSF012702 1 479 5.3E-170 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS12950 c5cb758ae69a36c1a4cdafb86441ef70 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 248 6.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12950 c5cb758ae69a36c1a4cdafb86441ef70 260 SUPERFAMILY SSF161098 54 236 2.88E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12950 c5cb758ae69a36c1a4cdafb86441ef70 260 Gene3D G3DSA:1.10.3720.10 52 247 7.8E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 SUPERFAMILY SSF46689 205 251 1.49E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 Gene3D G3DSA:3.40.50.880 3 210 6.0E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 Gene3D G3DSA:1.10.10.60 211 258 5.2E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 Pfam PF01965 DJ-1/PfpI family 64 166 4.2E-15 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 SUPERFAMILY SSF52317 1 187 8.84E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 SMART SM00342 221 304 3.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 Pfam PF12833 Helix-turn-helix domain 227 304 5.8E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 Gene3D G3DSA:1.10.10.60 259 306 3.0E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16565 aaa1244571d2206c5c496fce8fe1fa88 316 SUPERFAMILY SSF46689 257 307 6.57E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 11 471 1.8E-143 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Gene3D G3DSA:3.40.50.1480 392 472 3.9E-33 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Gene3D G3DSA:3.40.50.720 271 371 2.3E-16 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SMART SM00997 232 391 1.6E-114 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SMART SM00996 11 471 0.0 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SUPERFAMILY SSF52283 184 231 3.0E-110 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SUPERFAMILY SSF52283 392 472 3.0E-110 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SUPERFAMILY SSF52283 9 148 3.0E-110 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 232 391 6.9E-83 T 06-07-2017 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 SUPERFAMILY SSF51735 232 391 2.69E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 7 464 47.936 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 83 97 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Gene3D G3DSA:3.40.50.1480 8 147 5.2E-122 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 Gene3D G3DSA:3.40.50.1480 183 270 5.2E-122 T 06-07-2017 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 PIRSF PIRSF001109 1 472 1.2E-187 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 254 270 - T 06-07-2017 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS26620 a9cf5b178fb2647d3f65f618d3b8ab1b 472 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 12 464 2.6E-183 T 06-07-2017 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 Pfam PF08281 Sigma-70, region 4 130 182 1.7E-12 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 SUPERFAMILY SSF88946 14 122 8.37E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 Gene3D G3DSA:1.10.10.10 127 187 5.5E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 Pfam PF04542 Sigma-70 region 2 37 103 1.9E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 SUPERFAMILY SSF88659 124 185 2.8E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 184 3.4E-22 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19885 1b374f6d88c7d456695fce50e392ec62 190 Gene3D G3DSA:1.10.1740.10 16 126 1.7E-19 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 SUPERFAMILY SSF53706 10 756 1.96E-150 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 SMART SM00926 12 66 2.6E-18 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:2.40.40.20 761 929 1.5E-48 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:2.20.25.90 10 70 1.9E-21 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Pfam PF00384 Molybdopterin oxidoreductase 69 623 1.2E-33 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:3.40.50.740 71 146 1.6E-42 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:3.40.50.740 673 718 1.6E-42 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:3.40.50.740 424 631 1.6E-42 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 14 65 6.3E-16 T 06-07-2017 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:3.40.228.10 147 266 6.3E-58 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Gene3D G3DSA:3.40.228.10 328 423 6.3E-58 T 06-07-2017 CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 SUPERFAMILY SSF50692 780 934 2.49E-33 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS12905 cb44a01f8064b9726f21a854ed363c30 974 Pfam PF01568 Molydopterin dinucleotide binding domain 786 877 1.4E-13 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS02465 afcd59655573f8ae5de4ec8ba86b6e0f 257 SUPERFAMILY SSF52540 30 225 2.32E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02465 afcd59655573f8ae5de4ec8ba86b6e0f 257 Pfam PF00005 ABC transporter 44 171 1.9E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02465 afcd59655573f8ae5de4ec8ba86b6e0f 257 SMART SM00382 53 221 2.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02465 afcd59655573f8ae5de4ec8ba86b6e0f 257 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02465 afcd59655573f8ae5de4ec8ba86b6e0f 257 Gene3D G3DSA:3.40.50.300 27 223 2.6E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12370 e7c7c77cc7b5e0b857d32601005bd36a 326 Pfam PF00581 Rhodanese-like domain 209 299 1.1E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS12370 e7c7c77cc7b5e0b857d32601005bd36a 326 Gene3D G3DSA:3.40.250.10 202 300 1.5E-11 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS12370 e7c7c77cc7b5e0b857d32601005bd36a 326 SUPERFAMILY SSF52821 194 300 1.44E-13 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS12370 e7c7c77cc7b5e0b857d32601005bd36a 326 Pfam PF09335 SNARE associated Golgi protein 29 155 1.0E-13 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 226 312 1.2E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 Pfam PF00005 ABC transporter 31 177 2.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 SMART SM00382 39 226 3.5E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 Gene3D G3DSA:3.40.50.300 5 250 2.8E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 SUPERFAMILY SSF52540 23 248 5.0E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09800 71e4188c2f8dd8ccc17ea91496c5af6d 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 293 1.0E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS10305 f1ac6cc279cffa1fc18af4151bb1a8a7 110 Pfam PF00085 Thioredoxin 15 103 3.5E-14 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAL12_RS10305 f1ac6cc279cffa1fc18af4151bb1a8a7 110 SUPERFAMILY SSF52833 22 103 1.82E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10305 f1ac6cc279cffa1fc18af4151bb1a8a7 110 Gene3D G3DSA:3.40.30.10 13 106 3.0E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19505 1a4d3808b9d0a96eb893ec6e8c96771c 275 Gene3D G3DSA:3.40.50.300 32 266 1.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19505 1a4d3808b9d0a96eb893ec6e8c96771c 275 SMART SM00382 58 269 3.1E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19505 1a4d3808b9d0a96eb893ec6e8c96771c 275 SUPERFAMILY SSF52540 32 269 7.72E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19505 1a4d3808b9d0a96eb893ec6e8c96771c 275 Pfam PF00005 ABC transporter 49 199 3.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS19505 1a4d3808b9d0a96eb893ec6e8c96771c 275 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 Gene3D G3DSA:1.20.120.530 86 229 1.8E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 7.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 Gene3D G3DSA:1.10.10.10 20 83 6.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 SMART SM00895 93 217 1.8E-15 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 5.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 5.0E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 SMART SM00345 25 83 1.0E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 SUPERFAMILY SSF46785 22 87 3.54E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 SUPERFAMILY SSF48008 89 224 8.89E-23 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS27260 14550aa7493eedac78de121ffd6e6c74 241 Pfam PF07729 FCD domain 94 216 6.5E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS00935 fced9548009f4471a6fbfbe5ecac7555 288 SUPERFAMILY SSF53474 4 281 5.4E-83 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00935 fced9548009f4471a6fbfbe5ecac7555 288 Gene3D G3DSA:3.40.50.1820 4 281 5.9E-76 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00935 fced9548009f4471a6fbfbe5ecac7555 288 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 5 280 5.5E-131 T 06-07-2017 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 CAL12_RS00935 fced9548009f4471a6fbfbe5ecac7555 288 Pfam PF00756 Putative esterase 24 276 9.0E-52 T 06-07-2017 IPR000801 Putative esterase Reactome: R-HSA-156590 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Gene3D G3DSA:3.30.499.10 31 242 4.9E-54 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 ProSitePatterns PS01244 Aconitase family signature 2. 499 512 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 19 899 7.3E-300 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 SUPERFAMILY SSF53732 7 631 7.06E-178 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Gene3D G3DSA:3.40.1060.10 243 361 1.1E-30 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Gene3D G3DSA:3.30.499.10 425 579 1.7E-52 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Gene3D G3DSA:3.30.499.10 364 387 1.7E-52 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 ProSitePatterns PS00450 Aconitase family signature 1. 433 449 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Pfam PF00694 Aconitase C-terminal domain 699 825 1.2E-33 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 SUPERFAMILY SSF52016 636 899 1.24E-67 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 210 225 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 272 285 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 162 170 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 437 448 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 138 151 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 286 299 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 196 209 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 366 380 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 PRINTS PR00415 Aconitase family signature 499 512 8.8E-34 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Pfam PF00330 Aconitase family (aconitate hydratase) 71 567 1.1E-148 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS22885 42caaaad142192d9eb4a9af4a5ae6bb9 906 Gene3D G3DSA:3.20.19.10 643 899 5.4E-58 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS12795 04d4d8dfd22a5768aaac081d67dc07d4 247 SUPERFAMILY SSF52096 3 242 4.5E-43 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12795 04d4d8dfd22a5768aaac081d67dc07d4 247 Gene3D G3DSA:3.90.226.10 6 234 2.0E-39 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12795 04d4d8dfd22a5768aaac081d67dc07d4 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 213 2.0E-26 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 SUPERFAMILY SSF69189 302 394 6.47E-20 T 06-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 Gene3D G3DSA:2.60.410.10 303 391 1.1E-24 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 302 391 1.2E-18 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 SUPERFAMILY SSF56601 8 21 1.18E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 SUPERFAMILY SSF56601 54 302 1.18E-79 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 SMART SM00936 302 392 1.4E-25 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 82 93 6.5E-19 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 137 154 6.5E-19 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 164 177 6.5E-19 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 53 281 1.1E-78 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAL12_RS09345 2e0f968cb3515141610fba5bd95c2b00 417 Gene3D G3DSA:3.40.710.10 47 302 1.3E-95 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS12045 3d483c221812001fdf5ce956d3197907 108 SUPERFAMILY SSF160544 16 92 2.88E-21 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS12045 3d483c221812001fdf5ce956d3197907 108 Pfam PF01312 FlhB HrpN YscU SpaS Family 16 88 2.9E-16 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS12045 3d483c221812001fdf5ce956d3197907 108 Gene3D G3DSA:3.40.1690.10 16 92 4.5E-22 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 Gene3D G3DSA:3.40.640.10 99 375 1.2E-91 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 404 423 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 126 145 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 361 376 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 88 107 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 22 41 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 62 81 2.0E-19 T 06-07-2017 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 50 423 2.6E-64 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 304 325 - T 06-07-2017 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 Gene3D G3DSA:1.20.1340.10 18 95 2.5E-13 T 06-07-2017 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 Gene3D G3DSA:3.90.1150.10 376 488 9.7E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS07525 1861eb58d02c1a3162e24a3949a82b4b 499 SUPERFAMILY SSF53383 18 488 1.11E-120 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS10700 203c2b7c850b74cf357712e7453891b5 110 Pfam PF12823 Domain of unknown function (DUF3817) 12 98 6.6E-20 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAL12_RS10700 203c2b7c850b74cf357712e7453891b5 110 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 15 95 1.7E-23 T 06-07-2017 IPR023845 Domain of unknown function DUF3817, transmembrane CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 Pfam PF03466 LysR substrate binding domain 91 305 2.4E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 SUPERFAMILY SSF53850 91 307 1.3E-30 T 06-07-2017 CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 Gene3D G3DSA:1.10.10.10 9 86 9.4E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 Gene3D G3DSA:3.40.190.10 189 274 7.5E-15 T 06-07-2017 CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 Gene3D G3DSA:3.40.190.10 95 188 5.1E-9 T 06-07-2017 CAL12_RS05115 d9f814767c06df400c7e07a567e99e7e 309 SUPERFAMILY SSF46785 6 113 1.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 16 366 4.0E-119 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 Gene3D G3DSA:3.10.180.10 7 157 7.4E-48 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 8 154 1.6E-65 T 06-07-2017 CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 Gene3D G3DSA:3.10.180.10 171 366 1.9E-71 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 SUPERFAMILY SSF54593 7 353 1.54E-84 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 PIRSF PIRSF009283 1 367 6.2E-125 T 06-07-2017 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CAL12_RS22525 19d0516b5368fd0ce36bd433a75be575 375 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 176 286 1.8E-14 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 3.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 3.4E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 Pfam PF00106 short chain dehydrogenase 12 203 1.5E-57 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 SUPERFAMILY SSF51735 7 251 2.25E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 Gene3D G3DSA:3.40.50.720 4 252 2.9E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18485 63036997c3d57280813a79f1fcd65544 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.7E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17370 0009f5d59ab977f85c1b06cb2fe84ce8 216 Gene3D G3DSA:3.40.50.10610 18 201 2.6E-26 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS17370 0009f5d59ab977f85c1b06cb2fe84ce8 216 SUPERFAMILY SSF159594 27 196 9.15E-32 T 06-07-2017 CAL12_RS17370 0009f5d59ab977f85c1b06cb2fe84ce8 216 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 30 191 7.7E-39 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 SUPERFAMILY SSF56954 9 45 1.57E-98 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 SUPERFAMILY SSF56954 96 528 1.57E-98 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Gene3D G3DSA:1.20.1600.10 198 376 2.3E-83 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Gene3D G3DSA:1.20.1600.10 93 131 2.3E-83 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Gene3D G3DSA:1.20.1600.10 414 527 2.3E-83 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 527 2.4E-95 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Pfam PF02321 Outer membrane efflux protein 105 297 1.5E-22 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Pfam PF02321 Outer membrane efflux protein 343 509 2.9E-22 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Gene3D G3DSA:2.20.200.10 377 412 6.7E-21 T 06-07-2017 CAL12_RS02890 ad8aa1857334b68732b18291f08f76df 548 Gene3D G3DSA:2.20.200.10 142 197 6.7E-21 T 06-07-2017 CAL12_RS16985 cb18481c70a485403aab6037e9eaf612 330 Pfam PF00753 Metallo-beta-lactamase superfamily 79 263 2.5E-13 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS16985 cb18481c70a485403aab6037e9eaf612 330 Gene3D G3DSA:3.60.15.10 62 287 3.6E-43 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS16985 cb18481c70a485403aab6037e9eaf612 330 SUPERFAMILY SSF56281 27 304 2.71E-47 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS16985 cb18481c70a485403aab6037e9eaf612 330 SMART SM00849 80 263 4.0E-19 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24235 4cd125c37f6b1a0140a55f866fc11071 154 Pfam PF00075 RNase H 3 139 1.4E-47 T 06-07-2017 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CAL12_RS24235 4cd125c37f6b1a0140a55f866fc11071 154 SUPERFAMILY SSF53098 1 141 9.11E-57 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS24235 4cd125c37f6b1a0140a55f866fc11071 154 Gene3D G3DSA:3.30.420.10 4 143 2.8E-59 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS24235 4cd125c37f6b1a0140a55f866fc11071 154 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 33.91 T 06-07-2017 IPR022892 Ribonuclease H GO:0004523 CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 75 1.3E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 SMART SM00345 20 78 2.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 SUPERFAMILY SSF48008 86 220 1.05E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 SUPERFAMILY SSF46785 9 94 1.16E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 SMART SM00895 89 216 4.0E-8 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 Gene3D G3DSA:1.20.120.530 83 220 1.6E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 Pfam PF07729 FCD domain 92 214 1.0E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10320 61865261fe754039ce3dd8f895d31474 250 Gene3D G3DSA:1.10.10.10 6 77 1.2E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 Gene3D G3DSA:1.10.10.60 259 307 7.4E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 SMART SM00342 222 305 8.5E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 Gene3D G3DSA:3.40.50.880 3 211 2.4E-48 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 SUPERFAMILY SSF46689 205 252 2.87E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 Gene3D G3DSA:1.10.10.60 212 258 1.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 SUPERFAMILY SSF52317 1 188 2.32E-44 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 Pfam PF01965 DJ-1/PfpI family 28 167 3.3E-18 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 Pfam PF12833 Helix-turn-helix domain 228 306 2.8E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16880 c5bd5f0bbea5f95b292df64163cd0a9d 315 SUPERFAMILY SSF46689 258 307 1.97E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01525 11a11e5aed479eb35c41dd5c69f1ab9d 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 276 4.0E-46 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS22185 6bdd08244cd9cec526a24bf77796c369 266 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 26 266 2.7E-78 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS22185 6bdd08244cd9cec526a24bf77796c369 266 PIRSF PIRSF002854 1 266 6.3E-110 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS22185 6bdd08244cd9cec526a24bf77796c369 266 SUPERFAMILY SSF53850 31 266 6.52E-92 T 06-07-2017 CAL12_RS22185 6bdd08244cd9cec526a24bf77796c369 266 Gene3D G3DSA:3.40.190.10 28 158 5.2E-60 T 06-07-2017 CAL12_RS22185 6bdd08244cd9cec526a24bf77796c369 266 Pfam PF03180 NLPA lipoprotein 31 266 1.1E-99 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 79 97 1.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 266 284 1.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 38 54 1.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 60 76 1.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 Pfam PF13458 Periplasmic binding protein 37 345 1.7E-58 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 SUPERFAMILY SSF53822 37 399 2.55E-70 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS13340 13e0bc13f772035a5513fc678e736987 403 Gene3D G3DSA:3.40.50.2300 36 234 2.5E-51 T 06-07-2017 CAL12_RS15285 cd61c594ee591fcbf31af771e45b5e26 263 SMART SM00382 33 218 1.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15285 cd61c594ee591fcbf31af771e45b5e26 263 Gene3D G3DSA:3.40.50.300 2 241 6.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15285 cd61c594ee591fcbf31af771e45b5e26 263 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15285 cd61c594ee591fcbf31af771e45b5e26 263 SUPERFAMILY SSF52540 5 243 1.77E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15285 cd61c594ee591fcbf31af771e45b5e26 263 Pfam PF00005 ABC transporter 25 168 4.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 PIRSF PIRSF015601 3 243 2.1E-55 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 SUPERFAMILY SSF75217 77 241 1.62E-48 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 SUPERFAMILY SSF88697 4 55 5.3E-12 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 Gene3D G3DSA:3.40.1280.10 4 244 2.0E-78 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 Pfam PF04452 RNA methyltransferase 19 237 2.0E-65 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS05005 adbc6ef596b163be8ac0bc4b9e502fa6 253 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 5 241 1.6E-53 T 06-07-2017 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 SUPERFAMILY SSF90123 15 325 9.03E-47 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 Pfam PF00664 ABC transporter transmembrane region 29 291 3.3E-21 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 Gene3D G3DSA:1.20.1560.10 15 311 2.5E-39 T 06-07-2017 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 SUPERFAMILY SSF52540 334 579 4.3E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 SMART SM00382 369 555 5.2E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 Pfam PF00005 ABC transporter 362 509 2.3E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13360 5d89ed270a880060bfdbb24739a4e8da 592 Gene3D G3DSA:3.40.50.300 344 586 3.6E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Pfam PF00589 Phage integrase family 118 289 6.8E-49 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 16 303 3.7E-111 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Gene3D G3DSA:1.10.150.130 12 105 9.0E-26 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 304 57.096 T 06-07-2017 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 SUPERFAMILY SSF56349 16 294 5.0E-57 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 15 95 4.1E-19 T 06-07-2017 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Gene3D G3DSA:1.10.443.10 118 294 1.1E-56 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS12375 cc92398a4345664e82d3761613b1bde7 304 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 304 54.297 T 06-07-2017 IPR023009 Tyrosine recombinase XerC/XerD CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 PIRSF PIRSF000525 1 377 3.2E-141 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 376 49.027 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 204 223 - T 06-07-2017 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 SUPERFAMILY SSF53383 3 375 1.44E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 Gene3D G3DSA:3.40.640.10 18 274 9.5E-103 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 376 2.2E-143 T 06-07-2017 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 Pfam PF00266 Aminotransferase class-V 6 365 1.1E-46 T 06-07-2017 IPR000192 Aminotransferase class V domain CAL12_RS18950 33b7f4fca4dc66d65d188e2505ddcdee 377 Gene3D G3DSA:3.90.1150.10 275 376 1.6E-39 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 SUPERFAMILY SSF53706 1 653 1.18E-231 T 06-07-2017 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Pfam PF01568 Molydopterin dinucleotide binding domain 698 814 3.4E-15 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Gene3D G3DSA:3.40.50.740 332 481 8.3E-56 T 06-07-2017 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 SUPERFAMILY SSF50692 632 662 3.73E-44 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 SUPERFAMILY SSF50692 692 821 3.73E-44 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Pfam PF00384 Molybdopterin oxidoreductase 12 390 3.4E-20 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Gene3D G3DSA:2.40.40.20 691 821 5.7E-49 T 06-07-2017 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Gene3D G3DSA:2.40.40.20 619 659 5.7E-49 T 06-07-2017 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 733 760 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 820 0.0 T 06-07-2017 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Gene3D G3DSA:3.40.228.10 1 120 1.7E-75 T 06-07-2017 CAL12_RS19430 36307ae8f35b263e324133d8cb1b048b 821 Gene3D G3DSA:3.40.228.10 164 271 1.7E-75 T 06-07-2017 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 228 330 8.3E-31 T 06-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 333 25.97 T 06-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 8 95 9.9E-16 T 06-07-2017 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 201 332 4.1E-47 T 06-07-2017 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 SUPERFAMILY SSF63848 227 332 5.49E-30 T 06-07-2017 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 CAL12_RS05515 ada55a7712534bfb2886bab86094c146 334 Gene3D G3DSA:2.160.20.70 216 333 7.6E-37 T 06-07-2017 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 CAL12_RS12885 6a746ac9ca31586f31a2fadce9e8fcee 261 Pfam PF00005 ABC transporter 24 163 1.2E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12885 6a746ac9ca31586f31a2fadce9e8fcee 261 SUPERFAMILY SSF52540 6 234 3.74E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12885 6a746ac9ca31586f31a2fadce9e8fcee 261 SMART SM00382 33 214 1.3E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12885 6a746ac9ca31586f31a2fadce9e8fcee 261 Gene3D G3DSA:3.40.50.300 2 220 1.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12885 6a746ac9ca31586f31a2fadce9e8fcee 261 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 Pfam PF00501 AMP-binding enzyme 84 292 3.4E-18 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 SUPERFAMILY SSF56801 20 432 4.71E-68 T 06-07-2017 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 Gene3D G3DSA:3.30.300.30 328 436 2.9E-34 T 06-07-2017 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 Gene3D G3DSA:3.40.50.980 88 253 2.2E-16 T 06-07-2017 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 PIRSF PIRSF006444 3 437 4.6E-205 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 435 2.3E-219 T 06-07-2017 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CAL12_RS18645 283f1927570ea4ee93f13a7bd891bf98 437 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 435 1.4E-22 T 06-07-2017 IPR028154 AMP-dependent ligase, C-terminal CAL12_RS27010 41d24aa92a6ef0dea1a9980833776512 305 Pfam PF04321 RmlD substrate binding domain 2 300 2.3E-104 T 06-07-2017 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 CAL12_RS27010 41d24aa92a6ef0dea1a9980833776512 305 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 299 4.0E-97 T 06-07-2017 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 CAL12_RS27010 41d24aa92a6ef0dea1a9980833776512 305 Gene3D G3DSA:3.40.50.720 2 238 5.2E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27010 41d24aa92a6ef0dea1a9980833776512 305 SUPERFAMILY SSF51735 2 300 5.31E-98 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10830 5e07a370fd471ffc1188cd74c933d867 137 Gene3D G3DSA:3.30.1330.40 4 136 1.5E-36 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS10830 5e07a370fd471ffc1188cd74c933d867 137 SUPERFAMILY SSF55298 24 136 3.46E-27 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS10830 5e07a370fd471ffc1188cd74c933d867 137 Pfam PF01042 Endoribonuclease L-PSP 26 134 2.5E-18 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS13015 95bd97db528076520b1a13137432f5a0 367 Pfam PF07759 Protein of unknown function (DUF1615) 51 365 1.3E-142 T 06-07-2017 IPR011673 Protein of unknown function DUF1615 CAL12_RS13015 95bd97db528076520b1a13137432f5a0 367 ProDom PD041438 LIPOPROTEIN YAIW PRECURSOR SIGNAL MEMBRANE OUTER LIPOPROTEIN ECS0428 XAC0592 SECRETED 36 365 2.0E-123 T 06-07-2017 IPR011673 Protein of unknown function DUF1615 CAL12_RS07660 aebd4d3851bad847f8bd82e9eef442fe 66 ProDom PD004816 MACROPHAGE MIGRATION INHIBITORY FACTOR TAUTOMERASE MIF PHENYLPYRUVATE CYTOKINE RESPONSE INFLAMMATORY 3 55 4.0E-4 T 06-07-2017 IPR001398 Macrophage migration inhibitory factor CAL12_RS07660 aebd4d3851bad847f8bd82e9eef442fe 66 Gene3D G3DSA:3.30.429.20 1 61 2.1E-26 T 06-07-2017 CAL12_RS07660 aebd4d3851bad847f8bd82e9eef442fe 66 SUPERFAMILY SSF55331 2 62 9.56E-21 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS07660 aebd4d3851bad847f8bd82e9eef442fe 66 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 4.7E-18 T 06-07-2017 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 CAL12_RS07660 aebd4d3851bad847f8bd82e9eef442fe 66 Pfam PF01361 Tautomerase enzyme 2 59 1.1E-22 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 Gene3D G3DSA:2.40.50.100 218 253 3.1E-24 T 06-07-2017 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 Gene3D G3DSA:2.40.50.100 110 143 3.1E-24 T 06-07-2017 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 SUPERFAMILY SSF111369 101 336 1.27E-56 T 06-07-2017 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 Pfam PF13533 Biotin-lipoyl like 110 153 1.4E-15 T 06-07-2017 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 85 413 6.4E-74 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS25105 9b3a24f108360ad3c844a3c8d0f842f9 446 Pfam PF13437 HlyD family secretion protein 221 322 2.6E-8 T 06-07-2017 CAL12_RS12400 b60ae20287cb209935ccaf7d772efbe0 136 Gene3D G3DSA:1.10.10.10 7 82 1.4E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12400 b60ae20287cb209935ccaf7d772efbe0 136 SUPERFAMILY SSF46785 7 131 3.72E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12400 b60ae20287cb209935ccaf7d772efbe0 136 Pfam PF01475 Ferric uptake regulator family 11 129 3.3E-37 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 SUPERFAMILY SSF53732 6 470 1.02E-160 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 ProSitePatterns PS01244 Aconitase family signature 2. 404 417 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 113 121 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 348 359 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 124 137 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 404 417 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 200 213 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 214 227 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 138 153 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 PRINTS PR00415 Aconitase family signature 291 305 1.6E-45 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Pfam PF00330 Aconitase family (aconitate hydratase) 12 462 4.5E-147 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Gene3D G3DSA:3.30.499.10 297 308 1.9E-60 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Gene3D G3DSA:3.30.499.10 340 470 1.9E-60 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 6 471 55.472 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Gene3D G3DSA:3.40.1060.10 171 285 2.7E-37 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 Gene3D G3DSA:3.30.499.10 6 169 2.5E-24 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 ProSitePatterns PS00450 Aconitase family signature 1. 344 360 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS25405 ecafef76463a0e65246754308e8f3d42 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 7 468 3.4E-207 T 06-07-2017 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.463 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:1.10.1030.10 407 540 1.4E-54 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.40.50.20 541 664 1.7E-60 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF48108 403 556 1.7E-55 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 876 4.2E-37 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 3.0E-69 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.40.50.20 3 108 1.3E-43 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Pfam PF02142 MGS-like domain 958 1043 6.0E-20 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF52440 1 127 1.06E-48 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 1.1E-66 T 06-07-2017 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 1.1E-42 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF56059 675 935 3.89E-104 T 06-07-2017 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.30.1490.20 689 746 1.6E-26 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SMART SM00851 957 1044 9.7E-30 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF56059 128 408 7.78E-107 T 06-07-2017 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.40.50.1380 939 1076 1.1E-40 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF52335 937 1076 9.16E-38 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.232 T 06-07-2017 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SMART SM01096 426 549 9.9E-77 T 06-07-2017 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 SUPERFAMILY SSF52440 558 677 2.3E-49 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.30.1490.20 142 206 5.7E-24 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.30.470.20 207 406 2.7E-78 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS06505 4fc9624dba70dd70a3f629f8adf1bf16 1081 Gene3D G3DSA:3.30.470.20 747 936 6.3E-82 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS05265 478f1187b976488f17af34259e05b894 389 Gene3D G3DSA:3.40.50.2300 152 302 1.1E-25 T 06-07-2017 CAL12_RS05265 478f1187b976488f17af34259e05b894 389 Pfam PF13458 Periplasmic binding protein 28 367 1.3E-71 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS05265 478f1187b976488f17af34259e05b894 389 SUPERFAMILY SSF53822 28 379 5.8E-87 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS05265 478f1187b976488f17af34259e05b894 389 Gene3D G3DSA:3.40.50.2300 23 151 2.0E-44 T 06-07-2017 CAL12_RS05265 478f1187b976488f17af34259e05b894 389 Gene3D G3DSA:3.40.50.2300 303 357 2.0E-44 T 06-07-2017 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 38 340 2.2E-147 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Gene3D G3DSA:1.10.10.10 271 341 1.4E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Gene3D G3DSA:3.40.50.300 34 189 2.4E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Gene3D G3DSA:1.10.8.60 198 269 9.6E-33 T 06-07-2017 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 24 249 6.1E-118 T 06-07-2017 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 180.747 T 06-07-2017 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 264 338 1.0E-35 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 267 340 3.8E-34 T 06-07-2017 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 SMART SM00382 65 193 2.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 SUPERFAMILY SSF52540 34 264 1.43E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05565 532578a6f674db264a84528cacffa97b 357 SUPERFAMILY SSF46785 271 344 1.52E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 SUPERFAMILY SSF48498 78 192 2.45E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 SUPERFAMILY SSF46689 3 77 1.95E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 Gene3D G3DSA:1.10.357.10 70 192 3.9E-33 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.7E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 Gene3D G3DSA:1.10.10.60 1 64 2.8E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16945 e71159e5cf49e319889841e785e55e45 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS18290 98f29abded2ad4d2166df8fea7adde3b 124 Gene3D G3DSA:3.30.70.60 1 104 9.7E-42 T 06-07-2017 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CAL12_RS18290 98f29abded2ad4d2166df8fea7adde3b 124 Pfam PF01250 Ribosomal protein S6 3 91 1.9E-28 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18290 98f29abded2ad4d2166df8fea7adde3b 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 3.4E-34 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18290 98f29abded2ad4d2166df8fea7adde3b 124 SUPERFAMILY SSF54995 1 103 2.49E-37 T 06-07-2017 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18290 98f29abded2ad4d2166df8fea7adde3b 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 22.143 T 06-07-2017 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 Gene3D G3DSA:1.10.287.950 274 468 3.8E-45 T 06-07-2017 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 180 2.3E-21 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 SMART SM00283 263 496 1.2E-69 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 383 412 6.5E-28 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 277 306 6.5E-28 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 7 6.5E-28 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 354 381 6.5E-28 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 SUPERFAMILY SSF58104 236 497 1.96E-61 T 06-07-2017 CAL12_RS23735 f346f9b38fc31074285ffec002e90035 555 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 319 495 5.5E-39 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 Pfam PF16884 N-terminal domain of oxidoreductase 8 113 2.3E-37 T 06-07-2017 CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 SUPERFAMILY SSF50129 6 144 2.36E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 Gene3D G3DSA:3.40.50.720 141 304 5.3E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 Pfam PF00107 Zinc-binding dehydrogenase 159 294 6.4E-21 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 SUPERFAMILY SSF51735 125 303 8.77E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 SUPERFAMILY SSF50129 291 336 8.95E-6 T 06-07-2017 IPR011032 GroES-like CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 SMART SM00829 17 335 5.1E-5 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS19405 8b64b752a551141ee140b756aef621f6 338 Gene3D G3DSA:3.90.180.10 4 140 3.9E-51 T 06-07-2017 IPR011032 GroES-like CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 Gene3D G3DSA:1.10.10.10 13 95 4.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 7.0E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 Gene3D G3DSA:3.40.190.10 189 276 1.4E-12 T 06-07-2017 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 SUPERFAMILY SSF46785 14 117 1.08E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 SUPERFAMILY SSF53850 101 308 3.8E-25 T 06-07-2017 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 Pfam PF03466 LysR substrate binding domain 101 298 7.8E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 2.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 2.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 2.9E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03740 e1b328701caf35a8add03d47c37a6dad 329 Gene3D G3DSA:3.40.190.10 103 188 4.3E-22 T 06-07-2017 CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 Pfam PF08402 TOBE domain 291 369 2.1E-7 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 44 329 1.4E-109 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 SUPERFAMILY SSF52540 14 253 3.64E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 Pfam PF00005 ABC transporter 29 171 3.9E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 SUPERFAMILY SSF50331 246 341 1.02E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 SMART SM00382 38 221 1.7E-21 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS14425 98ebb4150992babd7a54776b17d2752c 373 Gene3D G3DSA:3.40.50.300 7 248 3.0E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 24.407 T 06-07-2017 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 78 3.1E-17 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 Pfam PF01197 Ribosomal protein L31 1 78 5.6E-26 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 PRINTS PR01249 Ribosomal protein L31 signature 59 77 1.0E-13 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 PRINTS PR01249 Ribosomal protein L31 signature 44 59 1.0E-13 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-13 T 06-07-2017 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18630 b0d3812ea35d50b24e19bc2524e6b68b 88 SUPERFAMILY SSF143800 1 78 9.42E-20 T 06-07-2017 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 Gene3D G3DSA:3.40.1740.10 19 55 9.7E-30 T 06-07-2017 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 Gene3D G3DSA:3.40.1740.10 141 187 9.7E-30 T 06-07-2017 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 SUPERFAMILY SSF143456 18 197 2.62E-60 T 06-07-2017 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 Gene3D G3DSA:3.30.70.1300 56 140 1.9E-28 T 06-07-2017 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 16 197 37.493 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAL12_RS24960 e3ab7af78c9cbbb0eecf120b25ef6ff1 197 Pfam PF02622 Uncharacterized ACR, COG1678 27 184 3.0E-46 T 06-07-2017 IPR003774 Protein of unknown function UPF0301 CAL12_RS05965 18524e43c45cc3f8dccac3e410306bed 336 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 8 322 4.1E-55 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS05965 18524e43c45cc3f8dccac3e410306bed 336 Gene3D G3DSA:3.30.1780.10 5 145 4.2E-33 T 06-07-2017 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CAL12_RS05965 18524e43c45cc3f8dccac3e410306bed 336 SUPERFAMILY SSF51735 5 331 1.29E-71 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05965 18524e43c45cc3f8dccac3e410306bed 336 PIRSF PIRSF001439 2 331 3.7E-72 T 06-07-2017 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CAL12_RS05965 18524e43c45cc3f8dccac3e410306bed 336 Gene3D G3DSA:3.40.50.720 146 301 2.4E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01850 20357482fc156d56c22ae63ff92524f0 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 209 3.5E-87 T 06-07-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 CAL12_RS01850 20357482fc156d56c22ae63ff92524f0 218 Pfam PF01144 Coenzyme A transferase 8 183 1.9E-37 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS01850 20357482fc156d56c22ae63ff92524f0 218 Gene3D G3DSA:3.40.810.20 7 213 5.0E-77 T 06-07-2017 CAL12_RS01850 20357482fc156d56c22ae63ff92524f0 218 SMART SM00882 8 205 1.0E-61 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS01850 20357482fc156d56c22ae63ff92524f0 218 SUPERFAMILY SSF100950 7 214 7.12E-65 T 06-07-2017 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 207 761 1.3E-152 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 SMART SM01008 74 191 3.3E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 676 824 2.6E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 421 518 2.6E-59 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 SUPERFAMILY SSF54665 57 212 5.5E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 180 234 2.9E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 344 418 2.9E-36 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 74 191 1.9E-26 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.90.1170.50 56 179 2.8E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 SUPERFAMILY SSF56003 183 824 1.96E-173 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 519 670 3.2E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS00185 fdbbbfa3c444ba47597541cf257e7c72 826 Gene3D G3DSA:3.30.365.10 235 342 6.6E-33 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 Pfam PF00005 ABC transporter 20 161 3.5E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 Gene3D G3DSA:3.40.50.300 3 233 4.8E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 Gene3D G3DSA:2.40.50.140 278 353 1.3E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 8 194 3.5E-39 T 06-07-2017 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 SUPERFAMILY SSF50331 239 359 2.31E-11 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 SMART SM00382 28 211 1.3E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 SUPERFAMILY SSF52540 4 240 4.33E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10440 a753d6b0bec9bbbc9f26aae8412d3417 366 Pfam PF08402 TOBE domain 275 360 3.6E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS12655 223a6ba31a6d3a2c56c8b7863bf9614a 317 SUPERFAMILY SSF53448 1 220 1.88E-48 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS12655 223a6ba31a6d3a2c56c8b7863bf9614a 317 Pfam PF00535 Glycosyl transferase family 2 1 121 4.7E-29 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS12655 223a6ba31a6d3a2c56c8b7863bf9614a 317 Gene3D G3DSA:3.90.550.10 1 195 6.1E-46 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 Gene3D G3DSA:1.10.10.10 4 88 3.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 SUPERFAMILY SSF53850 91 293 8.69E-39 T 06-07-2017 CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 Gene3D G3DSA:3.40.190.10 177 263 8.2E-17 T 06-07-2017 CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 Pfam PF03466 LysR substrate binding domain 90 292 5.0E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 SUPERFAMILY SSF46785 3 113 4.97E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07140 8022d10fd75e2253ead949c4a90ad5b3 314 Gene3D G3DSA:3.40.190.10 92 176 4.1E-16 T 06-07-2017 CAL12_RS17145 4b3afa91d5a98580fbc7837b258581e9 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 2.0E-33 T 06-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CAL12_RS17145 4b3afa91d5a98580fbc7837b258581e9 64 Gene3D G3DSA:1.10.10.600 1 63 9.6E-32 T 06-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CAL12_RS17145 4b3afa91d5a98580fbc7837b258581e9 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 1.8E-31 T 06-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CAL12_RS17145 4b3afa91d5a98580fbc7837b258581e9 64 PIRSF PIRSF039003 1 64 4.3E-34 T 06-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CAL12_RS17145 4b3afa91d5a98580fbc7837b258581e9 64 SUPERFAMILY SSF140319 1 62 3.53E-26 T 06-07-2017 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 Pfam PF07690 Major Facilitator Superfamily 30 326 2.7E-28 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 311 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 Gene3D G3DSA:1.20.1250.20 238 427 7.7E-27 T 06-07-2017 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 Gene3D G3DSA:1.20.1250.20 12 217 1.7E-23 T 06-07-2017 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS02140 e1940febe256886e9a920f90abf357d3 449 SUPERFAMILY SSF103473 12 427 5.89E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06770 045388115ac3890f5490a9e0a4dbab01 184 SUPERFAMILY SSF55729 23 183 4.73E-34 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS06770 045388115ac3890f5490a9e0a4dbab01 184 Pfam PF00583 Acetyltransferase (GNAT) family 83 157 2.8E-18 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS06770 045388115ac3890f5490a9e0a4dbab01 184 Gene3D G3DSA:3.40.630.30 23 183 1.3E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS10300 e9c4b181805f366f2594d537295a1222 355 SUPERFAMILY SSF53187 37 350 7.61E-57 T 06-07-2017 CAL12_RS10300 e9c4b181805f366f2594d537295a1222 355 PIRSF PIRSF039012 20 354 2.9E-75 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS10300 e9c4b181805f366f2594d537295a1222 355 Gene3D G3DSA:3.40.630.10 57 234 4.4E-22 T 06-07-2017 CAL12_RS10300 e9c4b181805f366f2594d537295a1222 355 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 69 350 2.3E-54 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 SUPERFAMILY SSF54211 5 108 1.06E-16 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 Gene3D G3DSA:3.30.230.10 3 109 4.8E-18 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 60 74 - T 06-07-2017 IPR020539 Ribonuclease P, conserved site GO:0004526 CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 48 96 4.0E-9 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 123 13.914 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAL12_RS27980 33d3d66c2b757bc80d785ceaa3163c10 125 Pfam PF00825 Ribonuclease P 6 110 5.4E-17 T 06-07-2017 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CAL12_RS15960 160f79874880242037cb99888000a061 250 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 29 250 5.2E-47 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAL12_RS15960 160f79874880242037cb99888000a061 250 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 250 2.7E-47 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 Gene3D G3DSA:2.60.120.10 138 217 3.5E-16 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 Gene3D G3DSA:1.10.260.40 36 137 7.0E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 Pfam PF07883 Cupin domain 160 212 1.1E-10 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 SUPERFAMILY SSF47413 34 96 9.86E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 SMART SM00530 39 94 2.6E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 Pfam PF13560 Helix-turn-helix domain 35 92 3.1E-16 T 06-07-2017 CAL12_RS04015 720598dd2f8343fbeac84e9b7b3ffc6b 224 SUPERFAMILY SSF51182 105 213 3.74E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 Gene3D G3DSA:3.40.50.300 346 591 1.3E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 SUPERFAMILY SSF52540 347 592 2.62E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 305 6.3E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 Pfam PF00005 ABC transporter 366 522 3.1E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 SMART SM00382 373 571 2.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05470 99b50144ab27ec83225fe58f096fec8b 596 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 571 593 8.1E-12 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 Gene3D G3DSA:3.30.420.40 3 129 1.6E-43 T 06-07-2017 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 PIRSF PIRSF001267 1 495 8.8E-188 T 06-07-2017 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 Gene3D G3DSA:3.30.420.150 130 306 1.4E-47 T 06-07-2017 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 SUPERFAMILY SSF53067 5 130 2.46E-34 T 06-07-2017 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 5 303 6.4E-98 T 06-07-2017 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 SUPERFAMILY SSF109604 310 492 2.51E-42 T 06-07-2017 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 SUPERFAMILY SSF53067 134 305 5.5E-41 T 06-07-2017 CAL12_RS06570 5e94b44f03cbddeb436f4e9fab0d9eb0 496 Pfam PF02541 Ppx/GppA phosphatase family 22 304 1.3E-76 T 06-07-2017 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 Gene3D G3DSA:1.20.120.530 84 224 1.1E-31 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 7.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 7.1E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 SUPERFAMILY SSF48008 86 223 1.1E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 Gene3D G3DSA:1.10.10.10 7 81 2.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 SMART SM00895 90 216 2.3E-16 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 5.8E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 SUPERFAMILY SSF46785 13 106 1.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 51 6.6E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 51 70 6.6E-5 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 SMART SM00345 22 80 2.7E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04105 d0047684f5cd03ca88ec22a85796daa0 239 Pfam PF07729 FCD domain 90 215 1.7E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 100 199 1.3E-17 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 169 189 1.6E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 1.6E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.6E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 196 209 1.6E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 SUPERFAMILY SSF56784 10 239 1.57E-43 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 Gene3D G3DSA:3.40.50.1000 9 227 5.5E-33 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 10 212 3.0E-48 T 06-07-2017 IPR006328 Haloacid dehalogenase, type II GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CAL12_RS04905 d19d23affbaf48debc2929e52bd4a1ad 245 Pfam PF00702 haloacid dehalogenase-like hydrolase 10 201 5.2E-9 T 06-07-2017 CAL12_RS13760 5cb066440058412edb610efb60d96b37 286 SUPERFAMILY SSF52540 9 241 1.91E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13760 5cb066440058412edb610efb60d96b37 286 SMART SM00382 37 230 2.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13760 5cb066440058412edb610efb60d96b37 286 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13760 5cb066440058412edb610efb60d96b37 286 Gene3D G3DSA:3.40.50.300 3 223 1.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13760 5cb066440058412edb610efb60d96b37 286 Pfam PF00005 ABC transporter 29 167 1.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 SUPERFAMILY SSF52540 198 447 2.62E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 SMART SM00382 217 415 8.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 Pfam PF00772 DnaB-like helicase N terminal domain 20 121 7.4E-34 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 Pfam PF03796 DnaB-like helicase C terminal domain 200 455 8.9E-116 T 06-07-2017 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 20 457 1.2E-174 T 06-07-2017 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 SUPERFAMILY SSF48024 18 129 1.7E-36 T 06-07-2017 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 Gene3D G3DSA:1.10.860.10 20 122 1.6E-36 T 06-07-2017 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CAL12_RS18265 8c064387e4cfd0ab7c73f35e7f693005 462 Gene3D G3DSA:3.40.50.300 184 456 7.7E-108 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 Gene3D G3DSA:3.40.190.10 91 204 3.1E-19 T 06-07-2017 CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 Gene3D G3DSA:3.40.190.10 205 250 3.0E-5 T 06-07-2017 CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 Gene3D G3DSA:1.10.10.10 5 87 1.6E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 SUPERFAMILY SSF53850 91 305 4.34E-24 T 06-07-2017 CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 SUPERFAMILY SSF46785 5 113 2.87E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 7.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23860 7959554d05e02557806aae3199aee4dd 312 Pfam PF03466 LysR substrate binding domain 92 301 1.4E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12820 f7123cc7a0b8c71638589b62773c90dd 250 Hamap MF_00943 Maleate isomerase [maiA]. 5 250 50.779 T 06-07-2017 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 CAL12_RS12820 f7123cc7a0b8c71638589b62773c90dd 250 PIRSF PIRSF015736 1 250 4.2E-70 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS02965 d3e436c84abb7f16db8669c47d129408 177 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 147 2.6E-46 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02965 d3e436c84abb7f16db8669c47d129408 177 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 147 1.6E-36 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02965 d3e436c84abb7f16db8669c47d129408 177 SUPERFAMILY SSF52121 7 151 1.44E-48 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02965 d3e436c84abb7f16db8669c47d129408 177 Gene3D G3DSA:3.40.50.960 7 151 1.5E-51 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02965 d3e436c84abb7f16db8669c47d129408 177 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 26.173 T 06-07-2017 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS21885 27f676cc7ad686aa0d2b20c7a24932e3 206 SUPERFAMILY SSF52218 1 200 6.93E-38 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS21885 27f676cc7ad686aa0d2b20c7a24932e3 206 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 199 23.386 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAL12_RS21885 27f676cc7ad686aa0d2b20c7a24932e3 206 Gene3D G3DSA:3.40.50.360 1 199 1.3E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS21885 27f676cc7ad686aa0d2b20c7a24932e3 206 Pfam PF02525 Flavodoxin-like fold 1 197 2.5E-34 T 06-07-2017 IPR003680 Flavodoxin-like fold CAL12_RS01240 2ab91f32b72a38910321ded3d7733782 396 SMART SM00267 210 392 3.9E-37 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS01240 2ab91f32b72a38910321ded3d7733782 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 388 3.2E-29 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS01240 2ab91f32b72a38910321ded3d7733782 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 220 392 8.2E-29 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS01240 2ab91f32b72a38910321ded3d7733782 396 SUPERFAMILY SSF55073 226 391 2.82E-34 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS01240 2ab91f32b72a38910321ded3d7733782 396 Gene3D G3DSA:3.30.70.270 223 393 3.5E-41 T 06-07-2017 CAL12_RS14760 999c93d8b8c8961505e5f8b9adddd9c2 170 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 27 93 1.0E-7 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS14760 999c93d8b8c8961505e5f8b9adddd9c2 170 SUPERFAMILY SSF53254 26 155 3.46E-13 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS14760 999c93d8b8c8961505e5f8b9adddd9c2 170 Gene3D G3DSA:3.40.50.1240 26 150 8.2E-14 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS14760 999c93d8b8c8961505e5f8b9adddd9c2 170 SMART SM00855 25 145 0.0021 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS03435 8dc3f666cf255995018516c5ff106838 2333 SMART SM00869 2058 2323 1.2E-21 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS03435 8dc3f666cf255995018516c5ff106838 2333 SUPERFAMILY SSF103515 2054 2333 1.23E-31 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS06145 a5e771d81af212dc02a9db9095675f4b 348 PIRSF PIRSF029792 1 332 2.6E-112 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS06145 a5e771d81af212dc02a9db9095675f4b 348 Gene3D G3DSA:3.10.310.10 1 155 1.1E-58 T 06-07-2017 CAL12_RS06145 a5e771d81af212dc02a9db9095675f4b 348 Pfam PF05544 Proline racemase 10 330 2.5E-115 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS06145 a5e771d81af212dc02a9db9095675f4b 348 SUPERFAMILY SSF54506 1 329 2.67E-95 T 06-07-2017 CAL12_RS06145 a5e771d81af212dc02a9db9095675f4b 348 Gene3D G3DSA:3.10.310.10 156 316 3.0E-54 T 06-07-2017 CAL12_RS02370 b666aae723c672d3448bd85b7b0ea959 527 Gene3D G3DSA:3.50.50.60 216 321 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02370 b666aae723c672d3448bd85b7b0ea959 527 Gene3D G3DSA:3.50.50.60 473 523 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02370 b666aae723c672d3448bd85b7b0ea959 527 Gene3D G3DSA:3.50.50.60 4 85 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02370 b666aae723c672d3448bd85b7b0ea959 527 SUPERFAMILY SSF51905 1 310 1.4E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02370 b666aae723c672d3448bd85b7b0ea959 527 Pfam PF01593 Flavin containing amine oxidoreductase 16 338 1.8E-15 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 Gene3D G3DSA:1.20.140.10 218 330 2.1E-22 T 06-07-2017 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 218 330 1.5E-14 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 SUPERFAMILY SSF47203 211 334 4.67E-23 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 Gene3D G3DSA:1.10.540.10 1 105 1.1E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 105 4.4E-12 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS16265 37faeb3f0059c574b4ae149c98c5f9f8 352 SUPERFAMILY SSF56645 1 181 9.82E-16 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 302 3.3E-61 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 PIRSF PIRSF000401 1 309 1.3E-85 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 308 31.906 T 06-07-2017 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 308 2.1E-82 T 06-07-2017 CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 Gene3D G3DSA:3.40.50.150 113 304 1.2E-38 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24860 fff1fb400cfbb4010a7dc3fc47cb6a81 309 SUPERFAMILY SSF53335 92 307 6.14E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS01070 f06613376b46c96968db2302696c618e 362 Pfam PF00534 Glycosyl transferases group 1 172 326 6.6E-22 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS01070 f06613376b46c96968db2302696c618e 362 Gene3D G3DSA:3.40.50.2000 163 326 8.9E-17 T 06-07-2017 CAL12_RS01070 f06613376b46c96968db2302696c618e 362 Pfam PF13439 Glycosyltransferase Family 4 13 160 3.8E-12 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS01070 f06613376b46c96968db2302696c618e 362 SUPERFAMILY SSF53756 6 352 2.62E-55 T 06-07-2017 CAL12_RS07450 13acd487b8ee14d41cd03ab9e083541e 348 Gene3D G3DSA:3.20.20.140 32 348 7.1E-41 T 06-07-2017 CAL12_RS07450 13acd487b8ee14d41cd03ab9e083541e 348 SUPERFAMILY SSF51556 40 348 9.53E-35 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS07450 13acd487b8ee14d41cd03ab9e083541e 348 Pfam PF04909 Amidohydrolase 41 348 7.7E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 Gene3D G3DSA:3.20.20.10 49 282 1.1E-82 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 SUPERFAMILY SSF50621 272 427 9.21E-55 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 238 254 - T 06-07-2017 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 20 426 1.2E-155 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 177 186 3.1E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 394 416 3.1E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 88 105 3.1E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 314 332 3.1E-30 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 303 404 1.4E-18 T 06-07-2017 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 SUPERFAMILY SSF51419 39 298 5.38E-81 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 384 397 5.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 286 305 5.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 70 88 5.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 5.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 90 102 5.6E-24 T 06-07-2017 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 28 427 41.432 T 06-07-2017 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 51 296 2.2E-70 T 06-07-2017 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CAL12_RS27450 3d03d3f75f5a82caf37fe5001ed6e7da 430 Gene3D G3DSA:2.40.37.10 283 427 2.1E-48 T 06-07-2017 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CAL12_RS08860 1f4fb6315c82487049886a6d74765996 371 SUPERFAMILY SSF52151 122 342 1.43E-51 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS08860 1f4fb6315c82487049886a6d74765996 371 SUPERFAMILY SSF52151 13 85 1.43E-51 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS08860 1f4fb6315c82487049886a6d74765996 371 Pfam PF01734 Patatin-like phospholipase 16 214 5.7E-25 T 06-07-2017 IPR002641 Patatin/Phospholipase A2-related GO:0006629 CAL12_RS08860 1f4fb6315c82487049886a6d74765996 371 Pfam PF12536 Patatin phospholipase 252 355 8.0E-32 T 06-07-2017 IPR021095 Protein of unknown function DUF3734 CAL12_RS08860 1f4fb6315c82487049886a6d74765996 371 Gene3D G3DSA:3.40.1090.10 18 217 9.8E-7 T 06-07-2017 CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 SUPERFAMILY SSF48008 90 229 5.75E-19 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 Gene3D G3DSA:1.20.120.530 87 231 1.1E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 SMART SM00895 93 224 2.9E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 Gene3D G3DSA:1.10.10.10 11 84 2.6E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 1.6E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 1.6E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 SMART SM00345 25 83 2.6E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 Pfam PF07729 FCD domain 93 217 1.8E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 SUPERFAMILY SSF46785 16 87 6.67E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04700 d43da1be169d3590d627d1281c840035 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 83 8.8E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10515 4fb783a16f6808c6cc0325c0e36ff10a 492 Gene3D G3DSA:2.130.10.10 38 352 9.6E-56 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS10515 4fb783a16f6808c6cc0325c0e36ff10a 492 Pfam PF02239 Cytochrome D1 heme domain 107 183 3.5E-6 T 06-07-2017 CAL12_RS10515 4fb783a16f6808c6cc0325c0e36ff10a 492 SUPERFAMILY SSF50974 3 351 5.23E-63 T 06-07-2017 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CAL12_RS10515 4fb783a16f6808c6cc0325c0e36ff10a 492 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 310 349 6.7E-10 T 06-07-2017 IPR011964 YVTN beta-propeller repeat CAL12_RS22235 13c3cc1db49c7de3fa4488c00ea4788f 136 Gene3D G3DSA:3.10.129.10 13 135 2.3E-35 T 06-07-2017 IPR029069 HotDog domain CAL12_RS22235 13c3cc1db49c7de3fa4488c00ea4788f 136 SUPERFAMILY SSF54637 17 135 4.73E-33 T 06-07-2017 IPR029069 HotDog domain CAL12_RS22235 13c3cc1db49c7de3fa4488c00ea4788f 136 Pfam PF03061 Thioesterase superfamily 32 107 1.1E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 SMART SM00079 46 266 0.0047 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 SUPERFAMILY SSF53850 17 266 9.78E-60 T 06-07-2017 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 Gene3D G3DSA:3.40.190.10 43 124 6.5E-35 T 06-07-2017 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 Gene3D G3DSA:3.40.190.10 226 268 6.5E-35 T 06-07-2017 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 SMART SM00062 46 267 2.9E-49 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 Gene3D G3DSA:3.40.190.10 125 225 7.0E-24 T 06-07-2017 CAL12_RS26320 c14377f9a75a46924c7aabe624f8922b 289 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 47 266 3.8E-55 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS12325 b446253d4507c29a8136eef46f561bd3 441 SUPERFAMILY SSF103473 12 395 7.19E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12325 b446253d4507c29a8136eef46f561bd3 441 Pfam PF07690 Major Facilitator Superfamily 20 296 3.3E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS12325 b446253d4507c29a8136eef46f561bd3 441 Gene3D G3DSA:1.20.1250.20 223 400 1.8E-15 T 06-07-2017 CAL12_RS12325 b446253d4507c29a8136eef46f561bd3 441 Gene3D G3DSA:1.20.1250.20 14 185 9.6E-19 T 06-07-2017 CAL12_RS02590 34bafc7a72e89e0ea8deb0710fe78837 256 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 6 249 5.6E-35 T 06-07-2017 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 CAL12_RS02590 34bafc7a72e89e0ea8deb0710fe78837 256 SUPERFAMILY SSF53167 6 246 6.15E-52 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS02590 34bafc7a72e89e0ea8deb0710fe78837 256 Gene3D G3DSA:3.40.50.1580 161 254 8.1E-60 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS02590 34bafc7a72e89e0ea8deb0710fe78837 256 Gene3D G3DSA:3.40.50.1580 5 129 8.1E-60 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS02590 34bafc7a72e89e0ea8deb0710fe78837 256 Pfam PF01048 Phosphorylase superfamily 6 251 3.5E-40 T 06-07-2017 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 Gene3D G3DSA:3.40.190.10 198 284 7.1E-6 T 06-07-2017 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 Gene3D G3DSA:1.10.10.10 27 106 6.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 59 70 8.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 59 8.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 8.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 82 1.5E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 Gene3D G3DSA:3.40.190.10 112 197 7.9E-24 T 06-07-2017 CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 Pfam PF03466 LysR substrate binding domain 108 315 1.9E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 SUPERFAMILY SSF46785 26 132 6.58E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04240 a685a453d918214a6459470c77092bb2 336 SUPERFAMILY SSF53850 109 320 1.99E-43 T 06-07-2017 CAL12_RS07670 4b90c649ea3a553fa1aac9ba342e0955 307 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 29 303 6.3E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07670 4b90c649ea3a553fa1aac9ba342e0955 307 SUPERFAMILY SSF53850 95 263 2.17E-10 T 06-07-2017 CAL12_RS07670 4b90c649ea3a553fa1aac9ba342e0955 307 PIRSF PIRSF017082 1 306 2.7E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 Gene3D G3DSA:1.20.1560.10 36 340 1.3E-32 T 06-07-2017 CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 SUPERFAMILY SSF90123 28 346 2.49E-46 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 SUPERFAMILY SSF52540 359 608 3.03E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 Gene3D G3DSA:3.40.50.300 368 603 1.9E-76 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 SMART SM00382 393 584 8.6E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 Pfam PF00005 ABC transporter 386 538 9.7E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23170 7203367f4883f31e6922967bd2ccd9eb 616 Pfam PF00664 ABC transporter transmembrane region 47 311 9.4E-12 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 Pfam PF00196 Bacterial regulatory proteins, luxR family 14 67 1.4E-19 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 SMART SM00421 12 69 1.6E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 SUPERFAMILY SSF46894 9 69 3.74E-19 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 Gene3D G3DSA:1.10.10.10 15 67 8.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 57 8.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 15 29 8.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS25130 792f8d692c8516661d2bf665c2400ea1 77 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 29 45 8.5E-12 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 SUPERFAMILY SSF81271 416 475 3.92E-18 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Pfam PF13291 ACT domain 665 741 8.6E-15 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Pfam PF13328 HD domain 36 199 2.8E-46 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 SUPERFAMILY SSF109604 11 213 9.1E-41 T 06-07-2017 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Gene3D G3DSA:3.30.70.260 668 737 1.5E-15 T 06-07-2017 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 SMART SM00954 258 368 2.7E-62 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Gene3D G3DSA:3.30.460.10 201 347 1.2E-50 T 06-07-2017 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Pfam PF04607 Region found in RelA / SpoT proteins 258 367 4.4E-36 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 SUPERFAMILY SSF55021 665 740 3.17E-14 T 06-07-2017 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Gene3D G3DSA:3.10.20.30 417 478 2.0E-21 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 SUPERFAMILY SSF81301 215 393 1.54E-61 T 06-07-2017 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 49 737 1.4E-167 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 CAL12_RS08250 ab4cab83da5ce180f2fbfddab75c5547 742 Pfam PF02824 TGS domain 417 475 3.6E-21 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 130 293 1.4E-65 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 273 281 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 SUPERFAMILY SSF53223 13 128 8.44E-34 T 06-07-2017 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 Gene3D G3DSA:3.40.50.720 148 277 2.3E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 Gene3D G3DSA:3.40.192.10 18 147 3.9E-44 T 06-07-2017 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 16 127 8.8E-34 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 SUPERFAMILY SSF51735 129 292 1.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 Hamap MF_01576 Bifunctional protein FolD [folD]. 13 296 36.224 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 164 184 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 213 242 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 269 287 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 81 108 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 252 268 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 40 62 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS06115 85957a79a9f9a4c2a0e9b687de972421 312 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 116 137 7.2E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 Pfam PF12833 Helix-turn-helix domain 189 264 2.8E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 218 259 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 Gene3D G3DSA:1.10.10.60 218 264 1.7E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 Gene3D G3DSA:2.60.120.10 23 98 4.0E-14 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 SMART SM00342 181 263 4.0E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 SUPERFAMILY SSF46689 218 265 8.06E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 247 3.1E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 247 263 3.1E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 Pfam PF02311 AraC-like ligand binding domain 37 107 2.2E-7 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 SUPERFAMILY SSF51182 18 190 4.35E-21 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS10090 8d903adbbd9034f8589fa7a843d6ce8f 269 Gene3D G3DSA:1.10.10.60 161 217 4.9E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS04185 fcaebd0419e1eb09b5a8e5fc02e8ff7a 204 Gene3D G3DSA:3.40.50.360 1 199 8.4E-64 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS04185 fcaebd0419e1eb09b5a8e5fc02e8ff7a 204 SUPERFAMILY SSF52218 1 200 1.47E-56 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS04185 fcaebd0419e1eb09b5a8e5fc02e8ff7a 204 Pfam PF02525 Flavodoxin-like fold 1 197 1.9E-46 T 06-07-2017 IPR003680 Flavodoxin-like fold CAL12_RS04185 fcaebd0419e1eb09b5a8e5fc02e8ff7a 204 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 198 30.419 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAL12_RS21675 5dec647eb2020af43eaa1537c479cfe9 419 SMART SM01329 30 415 7.5E-152 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS21675 5dec647eb2020af43eaa1537c479cfe9 419 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 419 2.9E-195 T 06-07-2017 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAL12_RS21675 5dec647eb2020af43eaa1537c479cfe9 419 Gene3D G3DSA:3.40.718.10 13 419 1.4E-142 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS21675 5dec647eb2020af43eaa1537c479cfe9 419 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 412 4.4E-101 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS21675 5dec647eb2020af43eaa1537c479cfe9 419 SUPERFAMILY SSF53659 4 419 4.42E-133 T 06-07-2017 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 PIRSF PIRSF005902 1 256 1.4E-76 T 06-07-2017 IPR001130 TatD family GO:0016788 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 6.0E-82 T 06-07-2017 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 Pfam PF01026 TatD related DNase 3 252 9.7E-76 T 06-07-2017 IPR001130 TatD family GO:0016788 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 Gene3D G3DSA:3.20.20.140 1 252 1.4E-85 T 06-07-2017 CAL12_RS15495 fda866ed669142637cb71fe3d9c7b64b 256 SUPERFAMILY SSF51556 1 253 7.25E-87 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 Gene3D G3DSA:3.40.190.10 130 220 2.5E-8 T 06-07-2017 CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 SMART SM00062 52 264 5.6E-16 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 Gene3D G3DSA:3.40.190.10 233 262 9.3E-10 T 06-07-2017 CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 Gene3D G3DSA:3.40.190.10 51 129 9.3E-10 T 06-07-2017 CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 262 6.8E-24 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS14010 bd82301599c435c683776fa0cbd52be1 276 SUPERFAMILY SSF53850 46 266 3.49E-32 T 06-07-2017 CAL12_RS03865 aefcb5eee7b3a58b221980e3d5957426 217 Pfam PF01613 Flavin reductase like domain 22 163 4.9E-17 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS03865 aefcb5eee7b3a58b221980e3d5957426 217 SUPERFAMILY SSF50475 2 191 5.4E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS03865 aefcb5eee7b3a58b221980e3d5957426 217 Gene3D G3DSA:2.30.110.10 11 186 1.3E-56 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS03865 aefcb5eee7b3a58b221980e3d5957426 217 SMART SM00903 19 168 2.0E-20 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 SUPERFAMILY SSF55031 185 298 2.22E-30 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 Pfam PF01546 Peptidase family M20/M25/M40 74 394 9.5E-39 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 PIRSF PIRSF005962 1 400 2.0E-127 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 SUPERFAMILY SSF53187 3 199 3.14E-90 T 06-07-2017 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 SUPERFAMILY SSF53187 300 398 3.14E-90 T 06-07-2017 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 Gene3D G3DSA:3.40.630.10 300 399 1.5E-104 T 06-07-2017 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 Gene3D G3DSA:3.40.630.10 4 180 1.5E-104 T 06-07-2017 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 Pfam PF07687 Peptidase dimerisation domain 187 280 1.0E-12 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 384 2.2E-111 T 06-07-2017 IPR017439 Amidohydrolase GO:0016787 CAL12_RS27930 03dd2a4d8348f952096db55fa0910ce8 400 Gene3D G3DSA:3.30.70.360 183 299 4.2E-40 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS17255 43c4711809480a48416f765748ae7719 298 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 2 298 50.876 T 06-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 293 3.4E-122 T 06-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 PIRSF PIRSF037167 1 298 1.4E-126 T 06-07-2017 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 Gene3D G3DSA:1.10.8.10 11 102 3.4E-8 T 06-07-2017 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 Gene3D G3DSA:3.40.50.150 104 265 7.9E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17255 43c4711809480a48416f765748ae7719 298 Pfam PF05175 Methyltransferase small domain 132 212 2.5E-15 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 11 295 3.4E-66 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CAL12_RS17255 43c4711809480a48416f765748ae7719 298 SUPERFAMILY SSF53335 13 266 5.78E-52 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17255 43c4711809480a48416f765748ae7719 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 202 208 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 SUPERFAMILY SSF50249 2 124 1.68E-46 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Gene3D G3DSA:2.30.30.30 119 195 1.5E-32 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 6.5E-32 T 06-07-2017 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Gene3D G3DSA:4.10.950.10 196 273 1.4E-34 T 06-07-2017 IPR014726 Ribosomal protein L2, domain 3 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 SMART SM01382 124 252 2.1E-87 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 PIRSF PIRSF002158 6 275 2.7E-100 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 06-07-2017 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 SMART SM01383 42 118 1.0E-42 T 06-07-2017 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 SUPERFAMILY SSF50104 127 272 2.17E-60 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Gene3D G3DSA:2.40.50.140 1 113 7.7E-48 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.065 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 1.4E-127 T 06-07-2017 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27640 cf5ee577264fc4a1c3eddb7e29f1e86a 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 1.1E-55 T 06-07-2017 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Gene3D G3DSA:3.40.50.300 6 293 5.0E-104 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SUPERFAMILY SSF54980 409 486 1.12E-25 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Pfam PF00679 Elongation factor G C-terminus 607 694 1.1E-31 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 9.5E-66 T 06-07-2017 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SUPERFAMILY SSF50447 271 409 1.44E-36 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SMART SM00838 607 695 1.2E-55 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Gene3D G3DSA:3.30.230.10 489 605 9.0E-50 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SUPERFAMILY SSF54211 484 606 2.33E-43 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Pfam PF14492 Elongation Factor G, domain II 409 483 6.2E-35 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 700 0.0 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.8E-19 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SMART SM00889 485 605 3.9E-76 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Gene3D G3DSA:2.40.30.10 310 410 4.5E-38 T 06-07-2017 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 110.809 T 06-07-2017 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Pfam PF03764 Elongation factor G, domain IV 484 605 3.8E-47 T 06-07-2017 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SUPERFAMILY SSF52540 6 288 2.82E-107 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Gene3D G3DSA:3.30.70.240 606 693 2.0E-34 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 1.6E-31 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 Gene3D G3DSA:3.30.70.870 411 485 3.7E-39 T 06-07-2017 CAL12_RS27670 132235a8596a567aaf061d9d6b3a1602 701 SUPERFAMILY SSF54980 610 697 2.45E-29 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 Gene3D G3DSA:3.40.50.1470 2 194 1.9E-71 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 Pfam PF01195 Peptidyl-tRNA hydrolase 7 190 1.4E-56 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 186 35.354 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 06-07-2017 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 SUPERFAMILY SSF53178 5 193 1.2E-66 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAL12_RS02810 60b9acf6ff4d6991e49637acea34e82c 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 193 1.4E-59 T 06-07-2017 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 ProSitePatterns PS00211 ABC transporters family signature. 484 498 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SUPERFAMILY SSF90123 6 315 9.68E-48 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Gene3D G3DSA:1.20.1560.10 6 315 1.3E-40 T 06-07-2017 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Gene3D G3DSA:1.20.1560.10 651 957 2.3E-44 T 06-07-2017 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Pfam PF00005 ABC transporter 365 511 9.2E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Pfam PF00005 ABC transporter 993 1142 1.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SUPERFAMILY SSF90123 651 964 6.15E-51 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 650 1172 1.0E-100 T 06-07-2017 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Gene3D G3DSA:3.40.50.300 976 1206 1.8E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Gene3D G3DSA:3.40.50.300 346 576 2.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 ProSitePatterns PS00211 ABC transporters family signature. 1114 1128 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SUPERFAMILY SSF52540 341 582 4.84E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SUPERFAMILY SSF52540 972 1207 1.15E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SMART SM00382 372 544 3.9E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 SMART SM00382 1002 1188 2.7E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Pfam PF00664 ABC transporter transmembrane region 22 280 1.7E-20 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS04305 c926e88462b74b44533f3840b76f931b 1211 Pfam PF00664 ABC transporter transmembrane region 664 925 2.8E-19 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 Gene3D G3DSA:3.40.30.10 3 83 5.7E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 Gene3D G3DSA:1.20.1050.10 84 201 2.1E-39 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 SUPERFAMILY SSF47616 91 204 1.39E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 Pfam PF02798 Glutathione S-transferase, N-terminal domain 6 80 1.8E-11 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 Pfam PF00043 Glutathione S-transferase, C-terminal domain 113 197 2.0E-10 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS19315 b342fa94ce8c991878099f721ee60bb8 210 SUPERFAMILY SSF52833 1 84 8.7E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18170 dec30bba1256a1c0eace1ee29b5f34a7 406 Pfam PF02515 CoA-transferase family III 5 383 4.1E-136 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS18170 dec30bba1256a1c0eace1ee29b5f34a7 406 Gene3D G3DSA:3.40.50.10540 316 406 4.1E-125 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS18170 dec30bba1256a1c0eace1ee29b5f34a7 406 Gene3D G3DSA:3.40.50.10540 3 227 4.1E-125 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS18170 dec30bba1256a1c0eace1ee29b5f34a7 406 Gene3D G3DSA:3.30.1540.10 233 315 2.4E-33 T 06-07-2017 CAL12_RS18170 dec30bba1256a1c0eace1ee29b5f34a7 406 SUPERFAMILY SSF89796 4 406 1.01E-145 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 Gene3D G3DSA:3.40.50.880 143 363 5.6E-76 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 124 1.6E-50 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 361 1.4E-138 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 Pfam PF00117 Glutamine amidotransferase class-I 184 358 6.2E-44 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 SMART SM01097 1 125 1.2E-85 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 365 44.755 T 06-07-2017 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 268 285 1.6E-37 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 267 1.6E-37 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 181 195 1.6E-37 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 220 234 1.6E-37 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 293 304 1.6E-37 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 262 7.5E-10 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 336 349 7.5E-10 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 PRINTS PR00096 Glutamine amidotransferase superfamily signature 223 232 7.5E-10 T 06-07-2017 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 SUPERFAMILY SSF52317 174 364 1.92E-58 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 Gene3D G3DSA:3.50.30.20 1 133 2.7E-58 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS06500 8a1f813b1b304cac511732febdd0dc0f 368 SUPERFAMILY SSF52021 1 131 9.29E-55 T 06-07-2017 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 CAL12_RS19000 41e6c2709bb3f0e1fba8104bedb47560 373 Gene3D G3DSA:3.20.20.70 29 371 1.3E-152 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS19000 41e6c2709bb3f0e1fba8104bedb47560 373 Pfam PF00793 DAHP synthetase I family 64 358 1.2E-97 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS19000 41e6c2709bb3f0e1fba8104bedb47560 373 PIRSF PIRSF001361 14 373 4.5E-159 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAL12_RS19000 41e6c2709bb3f0e1fba8104bedb47560 373 SUPERFAMILY SSF51569 27 369 5.68E-133 T 06-07-2017 CAL12_RS19000 41e6c2709bb3f0e1fba8104bedb47560 373 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 26 370 4.3E-153 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 Gene3D G3DSA:3.30.450.40 124 294 6.2E-28 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 Pfam PF09339 IclR helix-turn-helix domain 55 106 6.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 SMART SM00346 53 143 2.4E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 Pfam PF01614 Bacterial transcriptional regulator 177 268 3.9E-6 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 Gene3D G3DSA:1.10.10.10 52 123 8.9E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 SUPERFAMILY SSF46785 55 125 6.97E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22810 cbf33e0002bfb2deda2c39c12a409c76 300 SUPERFAMILY SSF55781 111 294 3.29E-27 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 SUPERFAMILY SSF51998 372 816 1.71E-181 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 SUPERFAMILY SSF51998 847 915 1.71E-181 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Gene3D G3DSA:3.20.70.20 285 494 5.1E-85 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Gene3D G3DSA:3.20.70.20 549 711 5.1E-85 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Gene3D G3DSA:3.20.70.20 873 914 5.1E-85 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Gene3D G3DSA:3.20.70.20 767 812 5.1E-85 T 06-07-2017 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 SUPERFAMILY SSF48168 156 371 1.29E-58 T 06-07-2017 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 295 915 3.3E-211 T 06-07-2017 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 767 794 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 625 648 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 583 594 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 663 685 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 691 714 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 PRINTS PR01183 Ribonucleotide reductase large chain signature 448 467 1.4E-44 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Pfam PF02867 Ribonucleotide reductase, barrel domain 373 912 1.9E-183 T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Pfam PF03477 ATP cone domain 34 130 1.2E-17 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 292 367 7.8E-20 T 06-07-2017 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24825 31ec373a32773405e9a603fc09d99933 977 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 756 778 - T 06-07-2017 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 Gene3D G3DSA:1.10.40.30 413 466 6.3E-14 T 06-07-2017 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 Gene3D G3DSA:1.10.275.10 8 143 1.1E-43 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 Gene3D G3DSA:1.20.200.10 144 404 1.5E-78 T 06-07-2017 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00149 Fumarate lyase superfamily signature 184 202 6.3E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 6.3E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00149 Fumarate lyase superfamily signature 321 337 6.3E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00149 Fumarate lyase superfamily signature 275 302 6.3E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 Pfam PF00206 Lyase 25 346 3.8E-82 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00145 Argininosuccinate lyase family signature 321 337 1.5E-5 T 06-07-2017 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00145 Argininosuccinate lyase family signature 138 160 1.5E-5 T 06-07-2017 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 PRINTS PR00145 Argininosuccinate lyase family signature 179 199 1.5E-5 T 06-07-2017 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 SUPERFAMILY SSF48557 8 464 9.27E-115 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 ProSitePatterns PS00163 Fumarate lyases signature. 321 330 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAL12_RS20110 c191b863a80d124181b04004766c3f39 489 Pfam PF10415 Fumarase C C-terminus 413 463 6.5E-13 T 06-07-2017 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CAL12_RS00100 3efcafd84afa5ac88fdaa563e108a6e3 253 Pfam PF10370 Domain of unknown function (DUF2437) 1 50 3.4E-16 T 06-07-2017 IPR018833 Domain of unknown function DUF2437 CAL12_RS00100 3efcafd84afa5ac88fdaa563e108a6e3 253 SUPERFAMILY SSF56529 53 250 6.67E-60 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS00100 3efcafd84afa5ac88fdaa563e108a6e3 253 Gene3D G3DSA:3.90.850.10 42 250 6.6E-62 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS00100 3efcafd84afa5ac88fdaa563e108a6e3 253 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 249 1.4E-51 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 9.3E-36 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 Gene3D G3DSA:3.40.50.720 1 167 2.7E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 SUPERFAMILY SSF48179 178 301 5.78E-21 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 Gene3D G3DSA:1.10.1040.10 177 301 2.6E-24 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 302 1.2E-54 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 299 1.0E-21 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS13045 e4f821a5778a1c40e24df360d342e533 316 SUPERFAMILY SSF51735 1 166 3.94E-13 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 SUPERFAMILY SSF53474 2 274 1.06E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 4.0E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.0E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 4.0E-10 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 Pfam PF00561 alpha/beta hydrolase fold 22 255 1.0E-28 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16375 1caf82222be25fd15707cb3dc56d29a8 274 Gene3D G3DSA:3.40.50.1820 3 273 2.0E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 SUPERFAMILY SSF64288 58 237 2.2E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 SMART SM00866 94 233 4.5E-37 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 SMART SM00345 11 70 2.3E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 Pfam PF07702 UTRA domain 95 233 9.7E-36 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 SUPERFAMILY SSF46785 2 74 2.9E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.5E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 Gene3D G3DSA:3.40.1410.10 67 237 6.9E-43 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 Gene3D G3DSA:1.10.10.10 2 66 1.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01275 2a6856e70caa1d3bbebb5cd19ff5d79a 261 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 4.4E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS06005 d624840bc9b12c9618e975fc5827c8bc 541 Pfam PF02653 Branched-chain amino acid transport system / permease component 248 524 1.1E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS06005 d624840bc9b12c9618e975fc5827c8bc 541 SUPERFAMILY SSF48371 127 237 2.88E-8 T 06-07-2017 IPR016024 Armadillo-type fold GO:0005488 CAL12_RS06005 d624840bc9b12c9618e975fc5827c8bc 541 Gene3D G3DSA:1.25.10.10 127 236 4.7E-6 T 06-07-2017 IPR011989 Armadillo-like helical CAL12_RS06005 d624840bc9b12c9618e975fc5827c8bc 541 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 248 538 6.1E-128 T 06-07-2017 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CAL12_RS16290 d68af3b6caaf05e6cd924e48fae98ca6 266 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS16290 d68af3b6caaf05e6cd924e48fae98ca6 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 265 3.2E-58 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS16290 d68af3b6caaf05e6cd924e48fae98ca6 266 Gene3D G3DSA:3.90.226.10 3 205 1.7E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16290 d68af3b6caaf05e6cd924e48fae98ca6 266 Gene3D G3DSA:1.10.12.10 208 266 3.0E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS16290 d68af3b6caaf05e6cd924e48fae98ca6 266 SUPERFAMILY SSF52096 3 265 3.27E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 Gene3D G3DSA:1.10.10.10 140 202 9.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 SUPERFAMILY SSF88946 40 113 3.34E-20 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 SUPERFAMILY SSF88659 136 202 3.55E-15 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 43 201 5.2E-28 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 Pfam PF04542 Sigma-70 region 2 46 110 5.9E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 Pfam PF08281 Sigma-70, region 4 145 197 5.2E-14 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS22030 ae6a9bec566d3006482bd8da4be602e8 210 Gene3D G3DSA:1.10.1740.10 40 139 3.5E-24 T 06-07-2017 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 Gene3D G3DSA:3.40.50.300 217 472 1.1E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 Gene3D G3DSA:3.30.450.90 81 210 7.7E-51 T 06-07-2017 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 SMART SM00382 238 361 1.3E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 305 319 - T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 2 471 4.7E-210 T 06-07-2017 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 Pfam PF00437 Type II/IV secretion system protein 115 377 1.4E-81 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 SUPERFAMILY SSF160246 2 64 9.42E-8 T 06-07-2017 CAL12_RS27355 fe6f23736b857e3d2f1e4f268d2d9158 474 SUPERFAMILY SSF52540 89 471 2.25E-99 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.5E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.5E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.5E-18 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 SUPERFAMILY SSF46785 5 66 6.58E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 SUPERFAMILY SSF54909 66 156 1.1E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 Gene3D G3DSA:1.10.10.10 7 58 1.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 Gene3D G3DSA:3.30.70.920 59 146 5.2E-35 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 SMART SM00344 6 118 5.8E-42 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.5E-22 T 06-07-2017 CAL12_RS22520 f3cb1166d26910b20a2005e4df05789d 158 Pfam PF01037 Lrp/AsnC ligand binding domain 72 149 3.0E-24 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 SUPERFAMILY SSF46785 4 86 8.86E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 Pfam PF03466 LysR substrate binding domain 88 292 1.9E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.2E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 Gene3D G3DSA:3.40.190.10 80 151 1.8E-8 T 06-07-2017 CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 SUPERFAMILY SSF53850 90 297 8.51E-45 T 06-07-2017 CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 Gene3D G3DSA:3.40.190.10 162 262 5.1E-19 T 06-07-2017 CAL12_RS01935 1cff319bcc399de96911529fdb57b52c 348 Gene3D G3DSA:1.10.10.10 3 79 3.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 Gene3D G3DSA:3.40.50.300 76 171 5.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 Gene3D G3DSA:3.40.50.300 240 326 5.8E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 PIRSF PIRSF000549 1 641 7.4E-296 T 06-07-2017 IPR016230 Serine-protein kinase, PrkA GO:0004672 CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 SUPERFAMILY SSF52540 76 344 1.83E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 SMART SM00763 20 377 1.8E-215 T 06-07-2017 IPR013153 PrkA AAA domain CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 Pfam PF06798 PrkA serine protein kinase C-terminal domain 380 633 7.7E-76 T 06-07-2017 IPR010650 PrkA C-terminal domain CAL12_RS24685 de90708de12bfe8dfaf87b7c957de6ad 641 Pfam PF08298 PrkA AAA domain 21 377 1.4E-173 T 06-07-2017 IPR013153 PrkA AAA domain CAL12_RS21670 189c27ee37e05c28b0cd9270343a81a0 166 SMART SM00530 5 64 5.1E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS21670 189c27ee37e05c28b0cd9270343a81a0 166 Pfam PF13560 Helix-turn-helix domain 4 60 5.9E-9 T 06-07-2017 CAL12_RS21670 189c27ee37e05c28b0cd9270343a81a0 166 Gene3D G3DSA:1.10.260.40 2 72 2.5E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS21670 189c27ee37e05c28b0cd9270343a81a0 166 SUPERFAMILY SSF47413 3 70 1.01E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS06525 b125342ff20389439332dd7bbe1767d3 144 Pfam PF14282 FlxA-like protein 69 140 4.9E-6 T 06-07-2017 IPR025577 FlxA-like protein CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 SMART SM00922 137 254 3.5E-18 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 116 4.1E-21 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 SUPERFAMILY SSF51604 104 382 5.37E-76 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 Gene3D G3DSA:3.20.20.120 124 371 7.1E-78 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 Pfam PF13378 Enolase C-terminal domain-like 142 377 1.8E-58 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 SUPERFAMILY SSF54826 1 121 2.69E-30 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS25955 4041cd411d328d65b9616bab44a5389f 390 Gene3D G3DSA:3.30.390.10 1 123 4.2E-42 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS10955 fddad321fe937bbce60c9295be99704b 344 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 327 7.7E-134 T 06-07-2017 IPR019949 Luciferase family oxidoreductase, group 1 CAL12_RS10955 fddad321fe937bbce60c9295be99704b 344 Gene3D G3DSA:3.20.20.30 8 326 1.1E-89 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAL12_RS10955 fddad321fe937bbce60c9295be99704b 344 Pfam PF00296 Luciferase-like monooxygenase 19 301 8.6E-37 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAL12_RS10955 fddad321fe937bbce60c9295be99704b 344 SUPERFAMILY SSF51679 7 327 1.28E-82 T 06-07-2017 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 Gene3D G3DSA:3.40.140.10 104 225 7.1E-43 T 06-07-2017 CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 Gene3D G3DSA:1.10.150.20 50 88 8.2E-4 T 06-07-2017 CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 Pfam PF04002 RadC-like JAB domain 106 224 1.5E-39 T 06-07-2017 IPR025657 RadC-like JAB domain CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 SUPERFAMILY SSF102712 120 198 3.79E-5 T 06-07-2017 CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 SUPERFAMILY SSF47781 17 90 4.82E-9 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 225 4.1E-66 T 06-07-2017 IPR001405 RadC protein CAL12_RS18625 462dc8ee351dc1d76c5ab07805f99810 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 175 180 - T 06-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site CAL12_RS22700 aec0349ae6d3af0a62293aa2f219f3c7 354 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 16 324 1.7E-88 T 06-07-2017 IPR010732 Type VI secretion, TssG-like CAL12_RS22700 aec0349ae6d3af0a62293aa2f219f3c7 354 Pfam PF06996 Type VI secretion, VasB, ImpH, VC_A0111 16 324 3.9E-89 T 06-07-2017 IPR010732 Type VI secretion, TssG-like CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 SUPERFAMILY SSF53850 89 297 2.64E-31 T 06-07-2017 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 Gene3D G3DSA:1.10.10.10 1 86 1.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.7E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 SUPERFAMILY SSF46785 1 110 6.99E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 Pfam PF03466 LysR substrate binding domain 87 280 1.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 Gene3D G3DSA:3.40.190.10 188 263 2.1E-10 T 06-07-2017 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 Gene3D G3DSA:3.40.190.10 90 187 2.0E-19 T 06-07-2017 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23275 d12314a568b87c224ba93befdf37d169 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 Pfam PF01070 FMN-dependent dehydrogenase 23 386 3.5E-116 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 SUPERFAMILY SSF51395 13 203 6.72E-86 T 06-07-2017 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 SUPERFAMILY SSF51395 236 386 6.72E-86 T 06-07-2017 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 Gene3D G3DSA:3.20.20.70 13 387 1.6E-116 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 PIRSF PIRSF000138 1 395 2.7E-121 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS18110 8744be05b52beaa44b2bde940797bacd 404 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 285 291 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 Gene3D G3DSA:3.40.190.10 86 194 3.2E-21 T 06-07-2017 CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 SUPERFAMILY SSF46785 1 109 7.62E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 Gene3D G3DSA:1.10.10.10 1 80 6.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 SUPERFAMILY SSF53850 83 279 2.44E-36 T 06-07-2017 CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 Gene3D G3DSA:3.40.190.10 195 262 1.3E-9 T 06-07-2017 CAL12_RS13970 0671bdcc5f582b556c41b7ecbf763fcd 317 Pfam PF03466 LysR substrate binding domain 87 283 1.2E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 SUPERFAMILY SSF53383 145 474 1.9E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 SUPERFAMILY SSF46785 14 93 6.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 SMART SM00345 25 84 2.6E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 Gene3D G3DSA:1.10.10.10 17 85 1.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 Gene3D G3DSA:3.90.1150.10 365 467 1.3E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 Gene3D G3DSA:3.40.640.10 155 364 3.0E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 Pfam PF00155 Aminotransferase class I and II 153 474 5.8E-36 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS02675 b9482751f6deca0f59f74c7f0f575100 504 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 3.8E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22255 3ab2d6478eee69354efe68c25308b691 566 Pfam PF06826 Predicted Permease Membrane Region 16 189 4.9E-23 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS22255 3ab2d6478eee69354efe68c25308b691 566 Pfam PF06826 Predicted Permease Membrane Region 393 559 1.8E-27 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS22255 3ab2d6478eee69354efe68c25308b691 566 Pfam PF02080 TrkA-C domain 311 379 1.6E-7 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22255 3ab2d6478eee69354efe68c25308b691 566 SUPERFAMILY SSF116726 296 380 3.27E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22255 3ab2d6478eee69354efe68c25308b691 566 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 397 549 1.6E-25 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 218 359 6.8E-18 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Gene3D G3DSA:3.30.530.20 215 361 3.9E-36 T 06-07-2017 IPR023393 START-like domain CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 SUPERFAMILY SSF55961 216 361 1.08E-25 T 06-07-2017 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Pfam PF01799 [2Fe-2S] binding domain 74 146 4.4E-22 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Gene3D G3DSA:3.10.20.30 2 75 6.7E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 59 5.1E-6 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 Gene3D G3DSA:1.10.150.120 76 156 1.3E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 SUPERFAMILY SSF54292 2 79 1.97E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 SUPERFAMILY SSF47741 85 157 9.81E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS12875 1fc8a84d02268802233f9ba30e5a94d3 393 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS00740 fb1310847cc4b19f99d24c9817ad1e17 153 Gene3D G3DSA:2.30.30.220 3 105 7.1E-43 T 06-07-2017 IPR007481 Stringent starvation protein B CAL12_RS00740 fb1310847cc4b19f99d24c9817ad1e17 153 SUPERFAMILY SSF101738 3 108 7.19E-42 T 06-07-2017 IPR007481 Stringent starvation protein B CAL12_RS00740 fb1310847cc4b19f99d24c9817ad1e17 153 PIRSF PIRSF005276 1 153 6.1E-47 T 06-07-2017 IPR007481 Stringent starvation protein B CAL12_RS00740 fb1310847cc4b19f99d24c9817ad1e17 153 Pfam PF04386 Stringent starvation protein B 5 153 3.3E-33 T 06-07-2017 IPR007481 Stringent starvation protein B CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 Pfam PF17152 Periplasmic sensor domain 45 146 1.4E-27 T 06-07-2017 IPR033417 Periplasmic sensor domain CHASE8 CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 Pfam PF00990 Diguanylate cyclase, GGDEF domain 249 405 4.0E-44 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 SUPERFAMILY SSF55073 254 407 2.9E-45 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 Pfam PF00672 HAMP domain 164 232 2.2E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 Gene3D G3DSA:3.30.70.270 251 407 5.5E-53 T 06-07-2017 CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 245 406 1.9E-42 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 SMART SM00267 238 411 1.5E-52 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS05185 1d2dbe46ea4f1df28ea1327a52f714e4 426 SMART SM00304 183 236 2.2E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS09730 a48f78dfc892b3bf4eb67ad7e803059a 518 SMART SM00052 269 513 8.4E-78 T 06-07-2017 IPR001633 EAL domain CAL12_RS09730 a48f78dfc892b3bf4eb67ad7e803059a 518 Pfam PF12792 CSS motif domain associated with EAL 42 242 3.3E-34 T 06-07-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain CAL12_RS09730 a48f78dfc892b3bf4eb67ad7e803059a 518 Gene3D G3DSA:3.20.20.450 273 513 1.2E-69 T 06-07-2017 IPR001633 EAL domain CAL12_RS09730 a48f78dfc892b3bf4eb67ad7e803059a 518 Pfam PF00563 EAL domain 276 508 1.1E-56 T 06-07-2017 IPR001633 EAL domain CAL12_RS09730 a48f78dfc892b3bf4eb67ad7e803059a 518 SUPERFAMILY SSF141868 276 514 2.35E-66 T 06-07-2017 IPR001633 EAL domain CAL12_RS20275 20a90cecd199ee0620feb4132cb1c546 235 Gene3D G3DSA:3.40.50.300 1 149 3.5E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20275 20a90cecd199ee0620feb4132cb1c546 235 SUPERFAMILY SSF52540 1 150 7.08E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 SUPERFAMILY SSF52540 13 204 3.14E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 TIGRFAM TIGR00436 era: GTP-binding protein Era 11 280 7.8E-78 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 170 9.8E-23 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 Pfam PF07650 KH domain 210 285 1.2E-15 T 06-07-2017 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 Hamap MF_00367 GTPase Era [era]. 8 297 33.479 T 06-07-2017 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 Pfam PF01926 50S ribosome-binding GTPase 13 126 7.3E-23 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 Gene3D G3DSA:3.30.300.20 194 293 1.0E-35 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 13 33 3.7E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 81 99 3.7E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 Gene3D G3DSA:3.40.50.300 8 193 7.6E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08420 de79c95dab67627d684d3da411277e60 298 SUPERFAMILY SSF54814 184 298 4.97E-38 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 Pfam PF13378 Enolase C-terminal domain-like 133 334 1.8E-30 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 SMART SM00922 130 226 4.0E-19 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 SUPERFAMILY SSF54826 1 104 2.7E-12 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 SUPERFAMILY SSF51604 115 333 5.24E-40 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 Gene3D G3DSA:3.30.390.10 1 104 8.9E-13 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS13205 b3b7d2010d81a53032f9899e0b58ed02 358 Gene3D G3DSA:3.20.20.120 109 333 4.3E-43 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS13405 488801aceb99478c1c2925cfa64053e4 229 Pfam PF03737 Demethylmenaquinone methyltransferase 32 176 3.9E-45 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS13405 488801aceb99478c1c2925cfa64053e4 229 Gene3D G3DSA:3.50.30.40 26 183 3.0E-52 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS13405 488801aceb99478c1c2925cfa64053e4 229 SUPERFAMILY SSF89562 26 184 1.7E-48 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS21045 5293f7777bf930c78dbbec2ebd5fc11b 316 Pfam PF00795 Carbon-nitrogen hydrolase 5 277 4.4E-56 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS21045 5293f7777bf930c78dbbec2ebd5fc11b 316 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 161 174 - T 06-07-2017 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CAL12_RS21045 5293f7777bf930c78dbbec2ebd5fc11b 316 Gene3D G3DSA:3.60.110.10 2 298 8.9E-76 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS21045 5293f7777bf930c78dbbec2ebd5fc11b 316 SUPERFAMILY SSF56317 1 298 1.57E-74 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS22945 f7f92959fd8412bf4990f6a7f076bdf7 223 Pfam PF01464 Transglycosylase SLT domain 96 198 2.3E-26 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAL12_RS22945 f7f92959fd8412bf4990f6a7f076bdf7 223 SUPERFAMILY SSF53955 87 221 2.85E-43 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS22945 f7f92959fd8412bf4990f6a7f076bdf7 223 Gene3D G3DSA:1.10.530.10 87 220 4.9E-47 T 06-07-2017 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 18 777 25.481 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 PIRSF PIRSF006076 5 777 1.1E-247 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Gene3D G3DSA:2.40.160.50 399 774 5.8E-27 T 06-07-2017 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF01103 Surface antigen 458 777 6.3E-69 T 06-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF07244 Surface antigen variable number repeat 186 273 7.7E-19 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF07244 Surface antigen variable number repeat 35 100 7.4E-6 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF07244 Surface antigen variable number repeat 357 431 2.9E-13 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF07244 Surface antigen variable number repeat 103 182 1.8E-9 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 Pfam PF07244 Surface antigen variable number repeat 276 353 3.1E-12 T 06-07-2017 IPR010827 Surface antigen variable number GO:0019867 CAL12_RS12155 4f5dc8b785ff31bf1763a3202848b5e5 777 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 34 777 1.1E-263 T 06-07-2017 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 CAL12_RS04820 8ee7126daabc0b9d7d408ac9f5bdefe3 365 SUPERFAMILY SSF53850 119 328 2.95E-15 T 06-07-2017 CAL12_RS04820 8ee7126daabc0b9d7d408ac9f5bdefe3 365 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 91 362 8.5E-93 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04820 8ee7126daabc0b9d7d408ac9f5bdefe3 365 PIRSF PIRSF017082 37 364 7.4E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 SUPERFAMILY SSF53720 2 481 1.2E-174 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 Pfam PF00171 Aldehyde dehydrogenase family 12 477 2.2E-179 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 Gene3D G3DSA:3.40.605.10 2 263 5.6E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27255 fb3594d7a66d2229323b29e898095189 492 Gene3D G3DSA:3.40.309.10 264 442 4.4E-73 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Gene3D G3DSA:3.40.50.1220 186 342 3.5E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 SUPERFAMILY SSF52518 358 559 1.98E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 SUPERFAMILY SSF52467 181 352 8.0E-42 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 168 1.8E-40 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 418 437 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 SUPERFAMILY SSF52518 3 182 1.04E-43 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Gene3D G3DSA:3.40.50.970 353 553 8.2E-56 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Gene3D G3DSA:3.40.50.970 2 174 6.2E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 527 4.7E-38 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS16665 6e47ffa28f9489c021f18acc3c4170f7 573 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 319 1.1E-26 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS21355 e63e92847875128a5ba6b1feaf5ed80f 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 6 213 8.7E-44 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS21355 e63e92847875128a5ba6b1feaf5ed80f 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 324 6.6E-99 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS21355 e63e92847875128a5ba6b1feaf5ed80f 335 PIRSF PIRSF000267 2 335 3.5E-89 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 23 264 38.015 T 06-07-2017 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 26 256 1.5E-62 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 SUPERFAMILY SSF51351 22 262 1.7E-86 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 ProSitePatterns PS00171 Triosephosphate isomerase active site. 184 194 - T 06-07-2017 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 Gene3D G3DSA:3.20.20.70 23 262 4.7E-97 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS20045 92c7d4cefc456fb4ba1c46293f7f77a2 264 Pfam PF00121 Triosephosphate isomerase 26 261 5.0E-84 T 06-07-2017 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 Pfam PF00005 ABC transporter 44 176 1.1E-19 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 SMART SM00382 53 227 8.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 Gene3D G3DSA:2.70.50.60 284 432 2.6E-41 T 06-07-2017 CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 Pfam PF14524 Wzt C-terminal domain 294 433 5.5E-28 T 06-07-2017 IPR029439 Wzt, C-terminal CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 Gene3D G3DSA:3.40.50.300 5 239 2.4E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26905 2b25ccbdee468476a723544f4a040080 441 SUPERFAMILY SSF52540 32 238 1.55E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07410 6834e99a94b27e2551b02597bf780d9d 406 SMART SM00558 104 230 7.7E-4 T 06-07-2017 IPR003347 JmjC domain CAL12_RS07410 6834e99a94b27e2551b02597bf780d9d 406 SUPERFAMILY SSF51197 12 312 8.79E-65 T 06-07-2017 CAL12_RS07410 6834e99a94b27e2551b02597bf780d9d 406 Pfam PF08007 Cupin superfamily protein 21 334 2.2E-87 T 06-07-2017 IPR003347 JmjC domain CAL12_RS07410 6834e99a94b27e2551b02597bf780d9d 406 Gene3D G3DSA:2.60.120.650 17 216 1.1E-39 T 06-07-2017 CAL12_RS25700 6c1df48904aec4fc1c19d75c95c6f1fc 337 SUPERFAMILY SSF53187 22 333 2.89E-54 T 06-07-2017 CAL12_RS25700 6c1df48904aec4fc1c19d75c95c6f1fc 337 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 52 232 2.5E-14 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS25700 6c1df48904aec4fc1c19d75c95c6f1fc 337 Gene3D G3DSA:3.40.630.10 52 224 1.1E-7 T 06-07-2017 CAL12_RS14525 d32f650623cd3b6ffc41e66ac5c635a5 375 Gene3D G3DSA:1.20.1090.10 187 375 2.1E-50 T 06-07-2017 CAL12_RS14525 d32f650623cd3b6ffc41e66ac5c635a5 375 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 366 1.2E-94 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAL12_RS14525 d32f650623cd3b6ffc41e66ac5c635a5 375 SUPERFAMILY SSF56796 6 375 4.58E-100 T 06-07-2017 CAL12_RS14525 d32f650623cd3b6ffc41e66ac5c635a5 375 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 175 203 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CAL12_RS14525 d32f650623cd3b6ffc41e66ac5c635a5 375 Gene3D G3DSA:3.40.50.1970 5 186 3.5E-43 T 06-07-2017 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 ProSitePatterns PS01312 SecA family signature. 500 515 - T 06-07-2017 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Pfam PF07516 SecA Wing and Scaffold domain 624 836 3.3E-68 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Gene3D G3DSA:3.40.50.300 369 416 4.7E-126 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Gene3D G3DSA:3.40.50.300 3 227 4.7E-126 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SMART SM00957 5 402 0.0 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Pfam PF01043 SecA preprotein cross-linking domain 232 358 2.7E-36 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Pfam PF02810 SEC-C motif 893 911 1.7E-10 T 06-07-2017 IPR004027 SEC-C motif CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Gene3D G3DSA:3.40.50.300 417 626 3.0E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Pfam PF07517 SecA DEAD-like domain 5 402 3.2E-132 T 06-07-2017 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Gene3D G3DSA:1.10.3060.10 655 838 1.9E-58 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 825 0.0 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF52540 368 415 1.16E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF52540 4 227 1.16E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 839 20.151 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 Gene3D G3DSA:3.90.1440.10 229 368 4.1E-45 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF52540 417 625 5.46E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SMART SM00958 227 358 5.6E-78 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 169 189 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 62 86 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 100 114 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 116 126 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 376 393 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 339 361 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 PRINTS PR00906 SecA protein signature 413 426 3.1E-73 T 06-07-2017 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF81886 889 901 3.53E-81 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF81886 628 847 3.53E-81 T 06-07-2017 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CAL12_RS22365 547b2b0aa49ee4253c498d34829ecab1 913 SUPERFAMILY SSF81767 226 368 8.24E-43 T 06-07-2017 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CAL12_RS11180 0398dc916a0e9ac86fe9271954d0dcd3 159 Gene3D G3DSA:3.10.180.10 2 131 5.5E-41 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS11180 0398dc916a0e9ac86fe9271954d0dcd3 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 119 1.4E-46 T 06-07-2017 IPR028973 PhnB-like CAL12_RS11180 0398dc916a0e9ac86fe9271954d0dcd3 159 SUPERFAMILY SSF54593 4 157 1.97E-48 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS11180 0398dc916a0e9ac86fe9271954d0dcd3 159 PIRSF PIRSF021700 1 159 6.1E-67 T 06-07-2017 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 Pfam PF00551 Formyl transferase 89 265 3.3E-40 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 SUPERFAMILY SSF55021 2 86 2.33E-21 T 06-07-2017 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 SUPERFAMILY SSF53328 89 284 2.35E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 6.3E-57 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 Gene3D G3DSA:3.30.70.260 2 83 6.0E-31 T 06-07-2017 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 Gene3D G3DSA:3.40.50.170 89 283 1.8E-57 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 Pfam PF13740 ACT domain 7 80 1.0E-6 T 06-07-2017 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 PIRSF PIRSF036480 3 284 2.1E-114 T 06-07-2017 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 7 283 8.5E-107 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS05380 9a7d6d4aeb9cd3ef9814ddbe7d323cc0 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 283 49.266 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS19645 e25d52883f16da49fd800cb10f4d1163 489 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 473 2.1E-137 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAL12_RS19645 e25d52883f16da49fd800cb10f4d1163 489 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 476 18.206 T 06-07-2017 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CAL12_RS19645 e25d52883f16da49fd800cb10f4d1163 489 Pfam PF00361 Proton-conducting membrane transporter 127 424 6.6E-75 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 443 2.7E-61 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 Gene3D G3DSA:3.90.76.10 72 160 4.8E-20 T 06-07-2017 CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 Gene3D G3DSA:3.40.190.10 161 297 4.3E-28 T 06-07-2017 CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 PIRSF PIRSF002741 1 520 1.8E-74 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 SUPERFAMILY SSF53850 38 519 2.17E-101 T 06-07-2017 CAL12_RS20100 a1ac2e008d964ccc30e5e897fecfaae8 536 Gene3D G3DSA:3.10.105.10 298 491 6.0E-37 T 06-07-2017 CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 5.2E-122 T 06-07-2017 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 Gene3D G3DSA:3.40.50.300 4 249 3.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 Pfam PF00005 ABC transporter 28 182 5.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 SMART SM00382 36 246 3.8E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS06595 b7a4d88b458f69d9ae76cd5583bef71a 258 SUPERFAMILY SSF52540 12 244 2.48E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07130 95783632d03912ab31bf413aa407eadf 323 SUPERFAMILY SSF53850 114 283 1.76E-13 T 06-07-2017 CAL12_RS07130 95783632d03912ab31bf413aa407eadf 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 5.2E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07130 95783632d03912ab31bf413aa407eadf 323 PIRSF PIRSF017082 1 323 4.3E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Gene3D G3DSA:1.10.760.10 326 416 9.8E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 SUPERFAMILY SSF46626 315 417 4.93E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Pfam PF00034 Cytochrome c 47 146 1.7E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Pfam PF00034 Cytochrome c 202 295 8.6E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 332 414 3.1E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 PIRSF PIRSF000018 14 442 2.5E-136 T 06-07-2017 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 SUPERFAMILY SSF46626 35 166 1.96E-25 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Gene3D G3DSA:1.10.760.10 188 295 1.9E-7 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 Gene3D G3DSA:1.10.760.10 44 145 3.0E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21730 3db2f8af8268c342f5fd97b0f676eb09 442 SUPERFAMILY SSF46626 180 307 3.54E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 Gene3D G3DSA:3.30.1330.60 78 192 2.7E-44 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01021 OMPA domain signature 91 113 1.6E-22 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01021 OMPA domain signature 121 136 1.6E-22 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01021 OMPA domain signature 136 152 1.6E-22 T 06-07-2017 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 ProSitePatterns PS01068 OmpA-like domain. 123 167 - T 06-07-2017 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 SUPERFAMILY SSF103088 81 191 2.88E-41 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 136 153 1.4E-10 T 06-07-2017 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 154 173 1.4E-10 T 06-07-2017 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 174 194 1.4E-10 T 06-07-2017 CAL12_RS18960 839db24ef5a9b54256d08176d1af05a0 199 Pfam PF00691 OmpA family 90 185 6.6E-27 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 3.0E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 190 0.0077 T 06-07-2017 CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 5.6E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 SUPERFAMILY SSF51735 9 254 4.64E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 Gene3D G3DSA:3.40.50.720 5 254 8.0E-88 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27125 78bdd2e7343d2b4a5cc19b78f524198f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 251 1.2E-68 T 06-07-2017 CAL12_RS07830 0727741d20e096ecb15d553f11b334fa 341 PIRSF PIRSF017082 12 341 1.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07830 0727741d20e096ecb15d553f11b334fa 341 Gene3D G3DSA:3.40.190.10 188 244 3.0E-4 T 06-07-2017 CAL12_RS07830 0727741d20e096ecb15d553f11b334fa 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 337 1.0E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07830 0727741d20e096ecb15d553f11b334fa 341 SUPERFAMILY SSF53850 130 299 1.17E-12 T 06-07-2017 CAL12_RS04030 111ae4e7b29f815b8ee577cfe13fed2f 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 7 125 2.3E-49 T 06-07-2017 IPR006056 RidA family CAL12_RS04030 111ae4e7b29f815b8ee577cfe13fed2f 128 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 06-07-2017 IPR019897 RidA, conserved site CAL12_RS04030 111ae4e7b29f815b8ee577cfe13fed2f 128 Gene3D G3DSA:3.30.1330.40 8 125 9.5E-47 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04030 111ae4e7b29f815b8ee577cfe13fed2f 128 Pfam PF01042 Endoribonuclease L-PSP 10 125 8.0E-41 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS04030 111ae4e7b29f815b8ee577cfe13fed2f 128 SUPERFAMILY SSF55298 5 126 7.7E-45 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS18345 bde82ff8115e307330d35056879dc7f1 553 SUPERFAMILY SSF109755 332 543 9.31E-19 T 06-07-2017 CAL12_RS18345 bde82ff8115e307330d35056879dc7f1 553 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 4 307 9.0E-65 T 06-07-2017 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 CAL12_RS18345 bde82ff8115e307330d35056879dc7f1 553 Pfam PF02690 Na+/Pi-cotransporter 163 289 1.3E-13 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CAL12_RS18345 bde82ff8115e307330d35056879dc7f1 553 Pfam PF02690 Na+/Pi-cotransporter 16 150 4.1E-34 T 06-07-2017 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 CAL12_RS05760 5d4603e2682568becdfafa6a53b4b053 194 Pfam PF09361 Phasin protein 7 104 2.6E-24 T 06-07-2017 IPR018968 Phasin CAL12_RS05760 5d4603e2682568becdfafa6a53b4b053 194 TIGRFAM TIGR01841 phasin: phasin family protein 27 109 1.4E-21 T 06-07-2017 IPR010127 Phasin, subfamily 1 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 Gene3D G3DSA:3.30.70.120 2 112 9.4E-50 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 PIRSF PIRSF039144 1 112 4.3E-54 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 5.5E-43 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 SUPERFAMILY SSF54913 2 112 1.33E-44 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 SMART SM00938 4 105 2.6E-66 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 PRINTS PR00340 P-II protein signature 52 75 2.9E-44 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 PRINTS PR00340 P-II protein signature 23 41 2.9E-44 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 PRINTS PR00340 P-II protein signature 83 103 2.9E-44 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 PRINTS PR00340 P-II protein signature 2 17 2.9E-44 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS15940 1b5085e1c7e4cdb6bfbde2d602e68065 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAL12_RS14540 fda25c7a2f09af15b388939dc9d0218b 374 Pfam PF11740 Plasmid replication region DNA-binding N-term 25 136 5.2E-27 T 06-07-2017 IPR021104 KfrA, N-terminal DNA-binding domain CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 Gene3D G3DSA:3.90.1150.10 404 535 6.2E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 Gene3D G3DSA:3.90.1150.10 344 358 6.2E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 SUPERFAMILY SSF53383 400 535 4.45E-45 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 SUPERFAMILY SSF53383 139 363 4.45E-45 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 Gene3D G3DSA:3.40.640.10 168 343 8.8E-34 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 33 552 2.8E-228 T 06-07-2017 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CAL12_RS18980 ef365f303db2fea6586553a063b68783 626 Pfam PF00155 Aminotransferase class I and II 212 534 1.9E-24 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 321 513 4.1E-64 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 Pfam PF02203 Tar ligand binding domain homologue 4 175 9.3E-29 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 Gene3D G3DSA:1.10.287.950 282 486 7.0E-62 T 06-07-2017 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 Pfam PF00672 HAMP domain 197 262 1.2E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 SUPERFAMILY SSF58104 234 519 5.62E-75 T 06-07-2017 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 SMART SM00304 214 266 6.0E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 5.1E-63 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 5.1E-63 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 5.1E-63 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 5.1E-63 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 5.1E-63 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13710 ae219c4f78919d1d49d767c8737895e9 540 SMART SM00283 267 514 9.6E-92 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS13725 94fe6c234c3b9d41b04ddac3eb0668a8 325 PIRSF PIRSF017082 1 324 5.2E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13725 94fe6c234c3b9d41b04ddac3eb0668a8 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 315 1.7E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13725 94fe6c234c3b9d41b04ddac3eb0668a8 325 SUPERFAMILY SSF53850 113 275 5.97E-10 T 06-07-2017 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 SUPERFAMILY SSF47384 190 271 9.42E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 SUPERFAMILY SSF55874 262 426 5.63E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Gene3D G3DSA:3.30.450.20 99 154 1.9E-5 T 06-07-2017 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 SMART SM00387 315 428 2.8E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 271 2.0E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 427 1.0E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 424 1.6E-124 T 06-07-2017 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Gene3D G3DSA:3.30.565.10 258 426 2.0E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Pfam PF11808 Domain of unknown function (DUF3329) 6 85 2.8E-9 T 06-07-2017 IPR021766 Protein of unknown function DUF3329 GO:0004673 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 Gene3D G3DSA:1.10.287.130 194 257 9.7E-22 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 SMART SM00388 203 272 4.8E-21 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 3.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 3.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 3.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS25605 3e0f372f738feb09349f173e46baa099 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 3.0E-13 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Gene3D G3DSA:3.90.1150.10 640 773 4.2E-6 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Gene3D G3DSA:3.40.640.10 560 637 2.1E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Gene3D G3DSA:3.40.640.10 296 518 2.1E-87 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Gene3D G3DSA:3.90.100.10 835 891 1.3E-7 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 296 520 8.1E-48 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 571 749 1.5E-18 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 SUPERFAMILY SSF53383 296 518 1.23E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS22250 7feed3bc0e06b9934fbb68df5ac4ba91 918 SUPERFAMILY SSF53383 560 771 1.23E-74 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SUPERFAMILY SSF47384 36 112 2.35E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SMART SM00387 159 275 1.1E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SMART SM00388 47 112 2.1E-23 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 235 253 1.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 272 1.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 218 228 1.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 PRINTS PR00344 Bacterial sensor protein C-terminal signature 200 214 1.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Gene3D G3DSA:3.40.50.2300 414 532 1.3E-33 T 06-07-2017 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Pfam PF00072 Response regulator receiver domain 416 530 1.0E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 159 272 6.0E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SMART SM00448 414 530 2.1E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SUPERFAMILY SSF55874 101 277 1.23E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Pfam PF00512 His Kinase A (phospho-acceptor) domain 47 112 2.2E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Gene3D G3DSA:3.30.565.10 117 275 3.2E-43 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 Gene3D G3DSA:1.10.287.130 39 108 5.9E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09740 b773e399f561bf0c68eefbc945724d25 545 SUPERFAMILY SSF52172 413 532 3.84E-30 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS02525 a65d203bee5d03ce664ad1720a3f2506 312 Pfam PF00682 HMGL-like 12 283 2.3E-49 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAL12_RS02525 a65d203bee5d03ce664ad1720a3f2506 312 SUPERFAMILY SSF51569 8 301 9.16E-76 T 06-07-2017 CAL12_RS02525 a65d203bee5d03ce664ad1720a3f2506 312 Gene3D G3DSA:3.20.20.70 10 295 5.5E-70 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 SUPERFAMILY SSF52540 546 742 1.57E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 Pfam PF02706 Chain length determinant protein 25 277 4.4E-26 T 06-07-2017 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 24 752 2.1E-149 T 06-07-2017 IPR005700 Exopolysaccharide transport protein GO:0006859|GO:0015542 CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 Gene3D G3DSA:3.40.50.300 548 725 1.7E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 533 737 3.4E-38 T 06-07-2017 IPR005702 Exopolysaccharide synthesis protein GO:0045226 CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 555 726 1.2E-14 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAL12_RS08020 0e85df62fcf3a65c1030248b5b193645 752 Pfam PF13807 G-rich domain on putative tyrosine kinase 394 475 2.4E-28 T 06-07-2017 IPR032807 Tyrosine kinase, G-rich domain CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 SUPERFAMILY SSF51161 4 263 2.92E-79 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 PIRSF PIRSF000456 1 264 1.0E-96 T 06-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 140 8.7E-10 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 16 49 8.3E-8 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Gene3D G3DSA:1.20.1180.10 194 263 3.8E-23 T 06-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 262 1.9E-27 T 06-07-2017 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Gene3D G3DSA:2.160.10.10 4 192 1.2E-50 T 06-07-2017 CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 263 44.671 T 06-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAL12_RS12175 b700667e4f911e30105c897c8a38c5e3 264 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 261 1.3E-97 T 06-07-2017 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Gene3D G3DSA:1.10.287.130 265 334 1.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 337 3.4E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Gene3D G3DSA:3.30.565.10 343 496 2.0E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 SUPERFAMILY SSF55874 327 483 4.71E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 SMART SM00387 383 497 6.6E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 SMART SM00304 220 272 0.0034 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 494 3.4E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Pfam PF00672 HAMP domain 205 268 2.6E-8 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 434 3.0E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 3.0E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 448 3.0E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 SMART SM00388 273 338 1.6E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 Pfam PF08521 Two-component sensor kinase N-terminal 52 196 1.4E-37 T 06-07-2017 IPR013727 Two-component sensor kinase, N-terminal CAL12_RS09465 6091e617eda910bb7395935d402976b1 501 SUPERFAMILY SSF47384 256 337 1.41E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 SMART SM00382 74 266 1.6E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 Gene3D G3DSA:3.40.50.300 37 290 6.1E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 268 333 5.4E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 SUPERFAMILY SSF52540 38 287 1.49E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 Pfam PF00005 ABC transporter 66 215 2.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 266 355 4.5E-24 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24310 49740e06f43b58e9a2630d61100940b5 378 ProSitePatterns PS00211 ABC transporters family signature. 189 203 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 Gene3D G3DSA:3.20.20.140 72 384 8.3E-101 T 06-07-2017 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 Gene3D G3DSA:2.30.40.10 8 71 4.7E-22 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 Gene3D G3DSA:2.30.40.10 385 463 1.0E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 SUPERFAMILY SSF51556 58 391 2.0E-95 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 Pfam PF01979 Amidohydrolase family 54 445 3.0E-25 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 SUPERFAMILY SSF51338 7 66 1.06E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 10 463 2.8E-165 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CAL12_RS24130 622342b4b7eac864fe8683d25ab17aaa 490 SUPERFAMILY SSF51338 363 464 1.73E-35 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 SUPERFAMILY SSF51735 3 247 6.56E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 175 0.0034 T 06-07-2017 CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 4.8E-59 T 06-07-2017 CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.7E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07720 6325a6cf9bfa327ec036426abdef8da4 248 Gene3D G3DSA:3.40.50.720 3 247 1.4E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01620 a151693810a1cce7113619ee34f2b734 183 Gene3D G3DSA:1.10.10.10 3 106 4.7E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01620 a151693810a1cce7113619ee34f2b734 183 SUPERFAMILY SSF46785 5 144 1.93E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01620 a151693810a1cce7113619ee34f2b734 183 Pfam PF01638 HxlR-like helix-turn-helix 20 106 3.0E-19 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS11910 203361f535acaf3fcdacdac89461cbe4 252 Pfam PF00460 Flagella basal body rod protein 5 35 5.3E-6 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAL12_RS11910 203361f535acaf3fcdacdac89461cbe4 252 SUPERFAMILY SSF117143 78 210 7.19E-18 T 06-07-2017 CAL12_RS11910 203361f535acaf3fcdacdac89461cbe4 252 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 172 248 2.8E-16 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAL12_RS11910 203361f535acaf3fcdacdac89461cbe4 252 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 122 8.1E-35 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAL12_RS11910 203361f535acaf3fcdacdac89461cbe4 252 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 73 370 5.0E-107 T 06-07-2017 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 SUPERFAMILY SSF56322 30 374 5.1E-103 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 Gene3D G3DSA:3.60.120.10 85 369 5.6E-112 T 06-07-2017 IPR005801 ADC synthase GO:0009058 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 Pfam PF00425 chorismate binding enzyme 113 366 3.3E-84 T 06-07-2017 IPR015890 Chorismate-utilising enzyme, C-terminal CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 PRINTS PR00095 Anthranilate synthase component I signature 228 241 5.3E-15 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 PRINTS PR00095 Anthranilate synthase component I signature 307 321 5.3E-15 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 PRINTS PR00095 Anthranilate synthase component I signature 322 336 5.3E-15 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS05430 42f8c424d52afed8f3832fc2823fd0f8 377 PRINTS PR00095 Anthranilate synthase component I signature 214 227 5.3E-15 T 06-07-2017 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Gene3D G3DSA:3.30.70.270 407 565 2.4E-49 T 06-07-2017 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 562 5.9E-42 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 SUPERFAMILY SSF55073 410 564 2.2E-43 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Gene3D G3DSA:3.30.450.20 187 303 4.9E-10 T 06-07-2017 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Gene3D G3DSA:3.30.450.20 93 186 3.7E-15 T 06-07-2017 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Pfam PF00672 HAMP domain 306 373 5.7E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 SMART SM00267 394 566 1.2E-48 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 Pfam PF02743 Cache domain 55 287 2.0E-13 T 06-07-2017 IPR033479 Double Cache domain 1 CAL12_RS05030 c8ea9fe8561f17224c5fd398eb43d965 567 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 402 565 9.7E-48 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 Pfam PF08402 TOBE domain 368 440 2.0E-14 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 117 439 2.4E-111 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 SMART SM00382 111 294 1.2E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 Gene3D G3DSA:3.40.50.300 86 319 5.3E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 Pfam PF00005 ABC transporter 102 244 2.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 SUPERFAMILY SSF50331 319 439 2.72E-16 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 SUPERFAMILY SSF52540 87 326 7.05E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13790 de49273d31f94ee025ce12cd53f2f88c 460 ProSitePatterns PS00211 ABC transporters family signature. 217 231 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07690 a08ded9469a6199896210ca680829918 240 PIRSF PIRSF026671 8 240 1.3E-57 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAL12_RS07690 a08ded9469a6199896210ca680829918 240 Pfam PF01427 D-ala-D-ala dipeptidase 51 239 7.5E-39 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAL12_RS07690 a08ded9469a6199896210ca680829918 240 Gene3D G3DSA:3.30.1380.10 49 239 8.2E-62 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAL12_RS07690 a08ded9469a6199896210ca680829918 240 SUPERFAMILY SSF55166 50 239 1.88E-53 T 06-07-2017 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5658034 CAL12_RS07690 a08ded9469a6199896210ca680829918 240 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 35 238 29.047 T 06-07-2017 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 529 4.3E-216 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Gene3D G3DSA:3.40.140.20 255 369 4.3E-49 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 SUPERFAMILY SSF53927 223 529 3.71E-126 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 SMART SM00851 15 130 1.8E-57 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 529 43.453 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 SUPERFAMILY SSF52335 3 198 3.66E-66 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Gene3D G3DSA:3.40.140.20 377 519 1.0E-56 T 06-07-2017 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 459 1.5E-117 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Gene3D G3DSA:3.40.50.1380 2 191 1.5E-80 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 PIRSF PIRSF000414 1 529 2.0E-212 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 SMART SM00798 135 461 6.1E-196 T 06-07-2017 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS05590 0c4c4d82bf57dce214456eb2f76e1c80 529 Pfam PF02142 MGS-like domain 15 129 2.3E-28 T 06-07-2017 IPR011607 Methylglyoxal synthase-like domain CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 SUPERFAMILY SSF54292 5 101 2.8E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 225 1.9E-54 T 06-07-2017 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 SUPERFAMILY SSF46548 102 230 6.28E-24 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 12 106 2.0E-28 T 06-07-2017 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 Pfam PF13183 4Fe-4S dicluster domain 144 213 1.8E-7 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 Gene3D G3DSA:3.10.20.30 4 101 3.7E-28 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 Gene3D G3DSA:1.10.1060.10 102 230 2.0E-25 T 06-07-2017 CAL12_RS07815 2a540bf7d142d8fc5730e0bf1dc072b2 237 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 51 59 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS26360 ca9710870e307406f0adc5f416115f31 176 Gene3D G3DSA:3.10.450.50 5 125 1.3E-6 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS26360 ca9710870e307406f0adc5f416115f31 176 SUPERFAMILY SSF54427 6 133 1.43E-11 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS23400 b7a1a5a44aa2b9ffc384aedb257fc9c5 586 SUPERFAMILY SSF143975 22 384 3.4E-117 T 06-07-2017 CAL12_RS23400 b7a1a5a44aa2b9ffc384aedb257fc9c5 586 SUPERFAMILY SSF52016 385 573 4.32E-55 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS23400 b7a1a5a44aa2b9ffc384aedb257fc9c5 586 Pfam PF00920 Dehydratase family 49 567 6.0E-177 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS23400 b7a1a5a44aa2b9ffc384aedb257fc9c5 586 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 132 142 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 SUPERFAMILY SSF51735 112 297 6.7E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 SUPERFAMILY SSF52283 25 144 1.32E-27 T 06-07-2017 CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 26 319 5.5E-19 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 206 228 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 Gene3D G3DSA:3.40.50.720 27 118 6.2E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 296 2.8E-61 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 Gene3D G3DSA:3.40.50.720 119 297 1.6E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10035 cc018fb90c6ca398f7a80a342d2a4f26 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 235 251 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS21760 b77dc438e8bccafcd79286e981671773 198 Gene3D G3DSA:1.20.1290.10 33 175 3.0E-14 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS21760 b77dc438e8bccafcd79286e981671773 198 SUPERFAMILY SSF69118 5 177 3.45E-21 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 Pfam PF03466 LysR substrate binding domain 88 292 8.2E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 SUPERFAMILY SSF46785 4 85 5.21E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 Gene3D G3DSA:3.40.190.10 178 257 4.6E-7 T 06-07-2017 CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 Gene3D G3DSA:1.10.10.10 3 84 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 Gene3D G3DSA:3.40.190.10 92 177 2.1E-22 T 06-07-2017 CAL12_RS14160 e350652dd1d9d383df063eac804a39e2 299 SUPERFAMILY SSF53850 90 293 6.15E-42 T 06-07-2017 CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 Pfam PF09339 IclR helix-turn-helix domain 2 49 6.1E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 Pfam PF01614 Bacterial transcriptional regulator 150 208 2.1E-7 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 SUPERFAMILY SSF46785 2 71 5.05E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 Gene3D G3DSA:1.10.10.10 1 61 3.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 Gene3D G3DSA:3.30.450.40 64 209 2.0E-30 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 SMART SM00346 1 88 2.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS14825 ef31f8f430bf156c3764bf090acb4bd6 222 SUPERFAMILY SSF55781 64 209 7.19E-26 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS23410 81a372681f2947a3f810b2e9b19862ec 500 Gene3D G3DSA:1.20.1250.20 305 490 8.7E-19 T 06-07-2017 CAL12_RS23410 81a372681f2947a3f810b2e9b19862ec 500 Gene3D G3DSA:1.20.1250.20 100 267 4.8E-19 T 06-07-2017 CAL12_RS23410 81a372681f2947a3f810b2e9b19862ec 500 Pfam PF07690 Major Facilitator Superfamily 108 451 6.9E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23410 81a372681f2947a3f810b2e9b19862ec 500 SUPERFAMILY SSF103473 92 489 1.57E-52 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS15295 1f6a07828c1836f310d95f6a45477969 232 Gene3D G3DSA:2.60.120.10 3 231 3.2E-75 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS15295 1f6a07828c1836f310d95f6a45477969 232 SUPERFAMILY SSF51182 1 231 2.16E-79 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS15295 1f6a07828c1836f310d95f6a45477969 232 Pfam PF02678 Pirin 7 119 2.9E-36 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAL12_RS15295 1f6a07828c1836f310d95f6a45477969 232 PIRSF PIRSF006232 1 230 3.4E-56 T 06-07-2017 IPR012093 Pirin CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 Pfam PF03466 LysR substrate binding domain 94 293 1.0E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 6.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 6.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 6.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 SUPERFAMILY SSF53850 97 298 2.44E-42 T 06-07-2017 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 SUPERFAMILY SSF46785 7 89 1.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 Gene3D G3DSA:3.40.190.10 94 180 1.3E-23 T 06-07-2017 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 Gene3D G3DSA:3.40.190.10 181 266 3.8E-30 T 06-07-2017 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.4E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23365 d4eb9859f8581a02878b1bc365c3aec1 305 Gene3D G3DSA:1.10.10.10 7 90 2.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 Pfam PF07690 Major Facilitator Superfamily 20 413 7.7E-56 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 490 2.7E-116 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 110 130 2.0E-5 T 06-07-2017 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 140 164 2.0E-5 T 06-07-2017 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 2.0E-5 T 06-07-2017 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 Gene3D G3DSA:1.20.1250.20 267 443 4.7E-16 T 06-07-2017 CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 SUPERFAMILY SSF103473 13 202 4.97E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 SUPERFAMILY SSF103473 252 423 4.97E-64 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS26140 c1b06c9407514c5514daa77148d41ae9 524 Gene3D G3DSA:1.20.1250.20 13 197 4.7E-30 T 06-07-2017 CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 SMART SM00382 34 226 4.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 PIRSF PIRSF039085 6 254 1.2E-108 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 SUPERFAMILY SSF52540 9 248 1.85E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 Gene3D G3DSA:3.40.50.300 8 251 6.2E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS11235 7b833bb7b1b4693fb8c99fa9da68e0d3 256 Pfam PF00005 ABC transporter 25 178 8.8E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 132 148 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 151 169 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 232 246 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 70 89 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 181 198 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 33 46 7.1E-55 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 137 160 - T 06-07-2017 IPR025505 FHIPEP conserved site CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 Pfam PF00771 FHIPEP family 26 686 1.9E-228 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 PIRSF PIRSF005419 1 696 2.5E-248 T 06-07-2017 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CAL12_RS22135 99841c156c6a2b6e9774a4e0674499a8 696 TIGRFAM TIGR01399 hrcV: type III secretion protein, HrcV family 14 694 3.9E-280 T 06-07-2017 IPR006302 Type III secretion protein HrcV GO:0015031|GO:0016021 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 121 203 1.14E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 294 365 1.3E-20 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 466 538 7.8E-16 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 123 189 8.0E-12 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 208 278 1.6E-23 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 37 103 6.9E-6 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Pfam PF00575 S1 RNA binding domain 380 452 2.2E-18 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 447 549 3.36E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 362 458 9.7E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 22 131 2.46E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 201 280 3.5E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 461 539 3.7E-21 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 119 191 3.1E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 230 251 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 57 71 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 173 193 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 348 366 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 102 121 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 308 327 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 39 57 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 126 142 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 PRINTS PR00681 Ribosomal protein S1 signature 144 161 1.6E-80 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 273 374 6.64E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 293 365 4.2E-24 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 380 452 8.6E-22 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 37 105 0.027 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 467 538 2.0E-17 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 208 278 1.9E-29 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SMART SM00316 121 189 3.5E-9 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 39 118 6.1E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 299 379 1.5E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 SUPERFAMILY SSF50249 208 295 1.29E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 Gene3D G3DSA:2.40.50.140 380 460 8.4E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18920 ca0598aa2733e1b49f7aae13a659e7e9 579 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 21 538 5.6E-205 T 06-07-2017 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 Gene3D G3DSA:3.30.450.40 89 264 2.8E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 SMART SM00346 20 111 5.9E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 SUPERFAMILY SSF55781 87 264 3.27E-30 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 Gene3D G3DSA:1.10.10.10 17 88 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 Pfam PF09339 IclR helix-turn-helix domain 23 74 5.2E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 SUPERFAMILY SSF46785 21 93 5.22E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05885 500aa2a40c458bde9ff859b8fff91a10 266 Pfam PF01614 Bacterial transcriptional regulator 144 261 8.6E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 Gene3D G3DSA:3.40.190.10 94 179 4.3E-25 T 06-07-2017 CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 SUPERFAMILY SSF53850 92 297 2.4E-43 T 06-07-2017 CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 SUPERFAMILY SSF46785 5 116 6.8E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 3.2E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 Pfam PF03466 LysR substrate binding domain 92 297 2.1E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 Gene3D G3DSA:3.40.190.10 180 268 3.8E-21 T 06-07-2017 CAL12_RS25160 9148fa73e85c28a3fd49b7bc0fcff79d 298 Gene3D G3DSA:1.10.10.10 6 92 6.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24095 79a245185d8033423264b17a5001793d 339 Pfam PF00005 ABC transporter 32 190 2.0E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24095 79a245185d8033423264b17a5001793d 339 SUPERFAMILY SSF52540 11 262 5.99E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24095 79a245185d8033423264b17a5001793d 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 305 1.2E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24095 79a245185d8033423264b17a5001793d 339 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24095 79a245185d8033423264b17a5001793d 339 SMART SM00382 40 240 2.1E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24095 79a245185d8033423264b17a5001793d 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 324 2.1E-25 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24095 79a245185d8033423264b17a5001793d 339 Gene3D G3DSA:3.40.50.300 11 264 3.6E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 Pfam PF03466 LysR substrate binding domain 87 294 1.9E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 Gene3D G3DSA:3.40.190.10 90 175 1.3E-16 T 06-07-2017 CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 SUPERFAMILY SSF46785 5 111 3.1E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 Gene3D G3DSA:1.10.10.10 5 82 5.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 SUPERFAMILY SSF53850 89 296 5.12E-35 T 06-07-2017 CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25695 6daf7a8d459c6f49485219527b2ceec8 329 Gene3D G3DSA:3.40.190.10 176 264 2.5E-13 T 06-07-2017 CAL12_RS23560 52937cd1ef6a0242b0c154a01b5aa8e5 142 Pfam PF07681 DoxX 22 102 6.3E-18 T 06-07-2017 IPR032808 DoxX family CAL12_RS24275 b26fadbee4bc9394cdddfc1783e32dc2 341 SUPERFAMILY SSF51430 1 318 6.55E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS24275 b26fadbee4bc9394cdddfc1783e32dc2 341 PRINTS PR00069 Aldo-keto reductase signature 143 160 4.3E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS24275 b26fadbee4bc9394cdddfc1783e32dc2 341 PRINTS PR00069 Aldo-keto reductase signature 112 130 4.3E-5 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS24275 b26fadbee4bc9394cdddfc1783e32dc2 341 Pfam PF00248 Aldo/keto reductase family 16 318 2.5E-68 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS24275 b26fadbee4bc9394cdddfc1783e32dc2 341 Gene3D G3DSA:3.20.20.100 1 319 1.7E-96 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS15985 57c78328adbecea16b363fac511954e7 253 Gene3D G3DSA:3.40.1210.10 1 246 9.6E-87 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAL12_RS15985 57c78328adbecea16b363fac511954e7 253 Pfam PF01975 Survival protein SurE 3 183 7.2E-57 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAL12_RS15985 57c78328adbecea16b363fac511954e7 253 SUPERFAMILY SSF64167 1 249 2.09E-83 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAL12_RS15985 57c78328adbecea16b363fac511954e7 253 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 251 38.215 T 06-07-2017 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAL12_RS15985 57c78328adbecea16b363fac511954e7 253 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 234 1.3E-63 T 06-07-2017 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 3.8E-24 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 20.308 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 06-07-2017 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 Gene3D G3DSA:2.30.30.30 3 90 6.2E-19 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 SUPERFAMILY SSF50104 3 99 1.35E-30 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAL12_RS27570 f97b89a813d64df7768132c4f2f63d1f 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 101 3.2E-32 T 06-07-2017 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 Gene3D G3DSA:2.40.50.140 1 66 3.2E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 PIRSF PIRSF002599 1 67 6.4E-22 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.9E-28 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 SMART SM00357 3 67 9.8E-27 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 PRINTS PR00050 Cold shock protein signature 4 19 8.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 PRINTS PR00050 Cold shock protein signature 40 58 8.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 PRINTS PR00050 Cold shock protein signature 25 34 8.8E-14 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 SUPERFAMILY SSF50249 1 66 1.42E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS20405 3602d2faa776ffa05b355a1074652672 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 Gene3D G3DSA:3.30.450.20 9 117 1.6E-9 T 06-07-2017 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 SUPERFAMILY SSF46894 111 178 5.1E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 SUPERFAMILY SSF55785 9 117 1.01E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 Gene3D G3DSA:1.10.10.10 126 174 9.1E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 Pfam PF00196 Bacterial regulatory proteins, luxR family 127 172 4.0E-16 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 SMART SM00421 124 181 2.3E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 ProSitePatterns PS00622 LuxR-type HTH domain signature. 141 168 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 169 3.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 127 141 3.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS00110 fc74d071ecd137185e7184a2a39aeeb5 187 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 157 3.7E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 SUPERFAMILY SSF64484 1133 1366 0.0 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 SUPERFAMILY SSF64484 16 944 0.0 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Gene3D G3DSA:2.40.50.100 1156 1208 4.0E-6 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Gene3D G3DSA:2.40.50.100 980 1018 1.5E-6 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 4.6E-24 T 06-07-2017 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 4.6E-86 T 06-07-2017 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Gene3D G3DSA:2.40.40.20 349 376 2.4E-36 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Gene3D G3DSA:2.40.40.20 417 489 2.4E-36 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 3.0E-18 T 06-07-2017 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 SMART SM00663 235 514 1.7E-172 T 06-07-2017 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1365 0.0 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 13 642 32.107 T 06-07-2017 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1375 10.439 T 06-07-2017 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 3.6E-8 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF00623 RNA polymerase Rpb1, domain 2 395 485 1.8E-26 T 06-07-2017 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS27745 1e1d99b5cd86bf09b91440c4e5cc5715 1415 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 1.8E-76 T 06-07-2017 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CAL12_RS19865 e28132bda58cd2394dc76534384e6868 318 Pfam PF05114 Protein of unknown function (DUF692) 30 293 1.1E-102 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAL12_RS19865 e28132bda58cd2394dc76534384e6868 318 SUPERFAMILY SSF51658 50 279 1.53E-10 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS19865 e28132bda58cd2394dc76534384e6868 318 Gene3D G3DSA:3.20.20.150 29 297 5.7E-99 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS19865 e28132bda58cd2394dc76534384e6868 318 Hamap MF_00697 UPF0276 protein . 30 303 46.118 T 06-07-2017 IPR007801 Uncharacterised protein family UPF0276 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 SUPERFAMILY SSF51735 12 212 1.15E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 199 205 - T 06-07-2017 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 Gene3D G3DSA:3.30.360.10 209 508 1.2E-116 T 06-07-2017 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 Gene3D G3DSA:3.40.50.720 17 208 5.7E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 23 209 4.9E-54 T 06-07-2017 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 19 509 5.5E-175 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 SUPERFAMILY SSF55347 204 508 2.94E-110 T 06-07-2017 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 212 508 4.5E-112 T 06-07-2017 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PIRSF PIRSF000110 2 511 6.5E-164 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 178 2.6E-45 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 259 275 2.6E-45 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 189 217 2.6E-45 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 241 258 2.6E-45 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 350 376 2.6E-45 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS22850 ceae338c3997485991e93f685f45151c 511 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 18 509 76.272 T 06-07-2017 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CAL12_RS06370 a593c83b80f993cbde65418c49b88934 177 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 96 107 - T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS06370 a593c83b80f993cbde65418c49b88934 177 SUPERFAMILY SSF55083 12 162 1.83E-51 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS06370 a593c83b80f993cbde65418c49b88934 177 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 13 141 6.3E-41 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS06370 a593c83b80f993cbde65418c49b88934 177 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 14 141 6.8E-37 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS06370 a593c83b80f993cbde65418c49b88934 177 Gene3D G3DSA:3.30.70.560 13 161 1.1E-52 T 06-07-2017 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS15330 b3209030eda1ca8ac0cf14b2fa78864c 208 Gene3D G3DSA:3.90.950.10 11 205 7.0E-73 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS15330 b3209030eda1ca8ac0cf14b2fa78864c 208 Pfam PF01725 Ham1 family 12 201 1.3E-51 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAL12_RS15330 b3209030eda1ca8ac0cf14b2fa78864c 208 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 12 203 1.2E-50 T 06-07-2017 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 CAL12_RS15330 b3209030eda1ca8ac0cf14b2fa78864c 208 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 10 205 48.197 T 06-07-2017 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 CAL12_RS15330 b3209030eda1ca8ac0cf14b2fa78864c 208 SUPERFAMILY SSF52972 11 204 4.71E-67 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 SUPERFAMILY SSF47203 246 394 2.09E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Gene3D G3DSA:2.40.110.10 135 231 9.0E-33 T 06-07-2017 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Gene3D G3DSA:1.20.140.10 232 392 5.9E-43 T 06-07-2017 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Gene3D G3DSA:1.10.540.10 5 134 1.0E-42 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 8.3E-28 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 5.6E-35 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 SUPERFAMILY SSF56645 7 243 2.36E-80 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS05340 6140e5dd57992803424e1a96a59cac9d 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 3.8E-22 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 PIRSF PIRSF019423 7 313 2.3E-140 T 06-07-2017 IPR011213 Nicotinic acid mononucleotide biosynthesis protein CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 SUPERFAMILY SSF46785 231 302 3.26E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 Gene3D G3DSA:1.10.10.10 236 302 2.4E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 Gene3D G3DSA:3.90.79.10 69 125 7.4E-8 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 Gene3D G3DSA:3.90.79.10 202 235 7.4E-8 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS24270 10b7ea0bff56001e089dccf5ad6b28d4 317 SUPERFAMILY SSF55811 22 130 1.64E-7 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS23590 c36f15b44f6f6d6db0c00729920b7436 250 Pfam PF06912 Protein of unknown function (DUF1275) 23 236 5.4E-40 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 Pfam PF08484 C-methyltransferase C-terminal domain 301 375 1.5E-13 T 06-07-2017 IPR013691 C-methyltransferase CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 Gene3D G3DSA:3.40.50.720 297 376 3.9E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 SUPERFAMILY SSF53335 83 254 2.52E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 Pfam PF13489 Methyltransferase domain 103 239 5.5E-16 T 06-07-2017 CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 Gene3D G3DSA:3.40.50.150 100 252 1.7E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS11760 b6af4f7a9f235e7da3c30526fae99ff2 393 SUPERFAMILY SSF51735 301 373 6.69E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 34 49 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 69 84 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 49 64 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 95 114 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 174 192 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 117 134 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 134 152 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 200 218 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 PRINTS PR01010 Flagellar P-ring protein signature 264 276 1.2E-84 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 Hamap MF_00416 Flagellar P-ring protein [flgI]. 14 378 38.158 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS11925 34388ad1060d24a9d560573f50e80469 378 Pfam PF02119 Flagellar P-ring protein 34 377 3.3E-134 T 06-07-2017 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 167 334 2.3E-53 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 Gene3D G3DSA:3.30.70.270 172 334 4.7E-54 T 06-07-2017 CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 Pfam PF00072 Response regulator receiver domain 20 132 3.7E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 Gene3D G3DSA:3.40.50.2300 17 158 1.0E-30 T 06-07-2017 CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 SMART SM00448 18 132 5.8E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 SUPERFAMILY SSF55073 175 336 2.28E-49 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 SUPERFAMILY SSF52172 15 152 6.83E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 SMART SM00267 159 335 4.9E-68 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19080 e2d42d600418782fa0ae5c68b8babc6f 338 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 331 2.8E-51 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.90.640.10 252 328 5.6E-7 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:2.60.34.10 406 546 1.5E-50 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 SUPERFAMILY SSF53067 213 394 5.18E-50 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:1.20.1270.10 547 634 1.2E-27 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 634 1.1E-265 T 06-07-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.30.420.40 6 46 2.8E-52 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.30.420.40 126 218 2.8E-52 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 218 231 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 635 41.846 T 06-07-2017 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 SUPERFAMILY SSF100934 523 634 1.45E-32 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 224 234 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 165 185 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 378 398 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 485 501 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 347 363 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 404 423 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 48 60 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 PRINTS PR00301 70kDa heat shock protein signature 20 33 1.6E-52 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.30.30.30 60 97 5.8E-6 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Pfam PF00012 Hsp70 protein 21 618 4.2E-170 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 SUPERFAMILY SSF100920 403 553 9.42E-47 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 SUPERFAMILY SSF53067 19 209 5.44E-49 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.30.420.40 332 374 2.2E-29 T 06-07-2017 CAL12_RS17155 55a09f6032e09d3e29f12b94afa22e9a 636 Gene3D G3DSA:3.30.420.40 219 251 2.2E-29 T 06-07-2017 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 Gene3D G3DSA:2.40.110.10 177 275 2.5E-22 T 06-07-2017 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 178 277 1.3E-17 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 SUPERFAMILY SSF47203 286 446 1.22E-36 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 Gene3D G3DSA:1.20.140.10 276 447 2.2E-37 T 06-07-2017 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 SUPERFAMILY SSF56645 93 297 1.44E-43 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 444 1.2E-29 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS21520 52ed5f0e5e6b361110ef44e477e5b686 557 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 403 422 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS24370 6cfb5a330179564ecae084aa04a82edc 486 SUPERFAMILY SSF75304 11 475 4.06E-110 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24370 6cfb5a330179564ecae084aa04a82edc 486 Pfam PF01425 Amidase 35 465 1.4E-93 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24370 6cfb5a330179564ecae084aa04a82edc 486 Gene3D G3DSA:3.90.1300.10 12 476 9.9E-113 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24370 6cfb5a330179564ecae084aa04a82edc 486 ProSitePatterns PS00571 Amidases signature. 161 192 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAL12_RS10400 e11afe3976c29a8aacd943538302076e 813 SUPERFAMILY SSF103642 356 374 1.18E-5 T 06-07-2017 CAL12_RS10400 e11afe3976c29a8aacd943538302076e 813 Gene3D G3DSA:3.10.450.50 326 373 1.4E-8 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS10400 e11afe3976c29a8aacd943538302076e 813 Pfam PF02810 SEC-C motif 357 372 6.5E-5 T 06-07-2017 IPR004027 SEC-C motif CAL12_RS10400 e11afe3976c29a8aacd943538302076e 813 Pfam PF14022 Protein of unknown function (DUF4238) 8 287 2.3E-10 T 06-07-2017 IPR025332 Protein of unknown function DUF4238 CAL12_RS04430 a5e39581a29d71980b48fabbf4831f82 326 PIRSF PIRSF017082 1 325 6.9E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04430 a5e39581a29d71980b48fabbf4831f82 326 Gene3D G3DSA:3.40.190.10 131 247 3.2E-5 T 06-07-2017 CAL12_RS04430 a5e39581a29d71980b48fabbf4831f82 326 SUPERFAMILY SSF53850 116 286 5.07E-15 T 06-07-2017 CAL12_RS04430 a5e39581a29d71980b48fabbf4831f82 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.1E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 Pfam PF01180 Dihydroorotate dehydrogenase 52 343 8.3E-84 T 06-07-2017 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 SUPERFAMILY SSF51395 8 343 1.73E-102 T 06-07-2017 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 PIRSF PIRSF000164 16 349 4.3E-93 T 06-07-2017 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 347 1.1E-121 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 06-07-2017 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 Gene3D G3DSA:3.20.20.70 7 346 1.9E-122 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS05765 11fe40a842ce2057d715d279675b68e5 349 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 7 344 48.849 T 06-07-2017 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 SUPERFAMILY SSF103473 257 460 2.62E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 SUPERFAMILY SSF103473 22 208 2.62E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 Pfam PF07690 Major Facilitator Superfamily 29 418 4.2E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 Gene3D G3DSA:1.20.1250.20 23 203 4.8E-23 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 Gene3D G3DSA:1.20.1250.20 270 463 6.4E-22 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 5.2E-6 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 28 52 5.2E-6 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 119 139 5.2E-6 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 276 301 5.2E-6 T 06-07-2017 CAL12_RS23155 e8bcdf0314c434a3af139f4fc884ff04 465 PRINTS PR01036 Tetracycline resistance protein TetB signature 311 335 5.2E-6 T 06-07-2017 CAL12_RS26700 189e180ee751d53d7fb2d0c6879053de 219 Pfam PF04340 Protein of unknown function, DUF484 7 217 1.2E-27 T 06-07-2017 IPR007435 Protein of unknown function DUF484 CAL12_RS00130 11e715c7f4169735fb6280f586b05424 323 SUPERFAMILY SSF53850 109 282 8.51E-12 T 06-07-2017 CAL12_RS00130 11e715c7f4169735fb6280f586b05424 323 Gene3D G3DSA:3.40.190.10 127 233 8.4E-4 T 06-07-2017 CAL12_RS00130 11e715c7f4169735fb6280f586b05424 323 PIRSF PIRSF017082 1 321 1.2E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00130 11e715c7f4169735fb6280f586b05424 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 315 6.0E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 Pfam PF00005 ABC transporter 46 186 2.6E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 SUPERFAMILY SSF52540 29 249 1.02E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 SMART SM00382 54 216 4.9E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 Hamap MF_00677 UPF0261 protein . 395 792 47.811 T 06-07-2017 IPR008322 Uncharacterised protein family UPF0261 CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 Gene3D G3DSA:3.40.50.300 28 251 4.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12475 ae89a9736c5778a9d09c3e4f3111f54e 815 Pfam PF06792 Uncharacterised protein family (UPF0261) 397 789 1.8E-153 T 06-07-2017 IPR008322 Uncharacterised protein family UPF0261 CAL12_RS04005 608a17ed6985def55f288b6e0a44e8ed 541 Gene3D G3DSA:3.40.190.10 152 314 4.5E-39 T 06-07-2017 CAL12_RS04005 608a17ed6985def55f288b6e0a44e8ed 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 454 4.8E-74 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS04005 608a17ed6985def55f288b6e0a44e8ed 541 PIRSF PIRSF002741 7 539 1.1E-80 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS04005 608a17ed6985def55f288b6e0a44e8ed 541 SUPERFAMILY SSF53850 37 532 3.62E-104 T 06-07-2017 CAL12_RS04005 608a17ed6985def55f288b6e0a44e8ed 541 Gene3D G3DSA:3.10.105.10 315 508 4.0E-37 T 06-07-2017 CAL12_RS22060 1f93aa4c50753eb8d4815c70f0dc13a2 437 TIGRFAM TIGR02551 SpaO_YscQ: type III secretion apparatus protein, YscQ/HrcQ family 154 429 2.2E-34 T 06-07-2017 IPR013385 Type III secretion system apparatus protein YscQ/HrcQ/SpaO GO:0030254 CAL12_RS22060 1f93aa4c50753eb8d4815c70f0dc13a2 437 SUPERFAMILY SSF101801 359 432 3.27E-14 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS22060 1f93aa4c50753eb8d4815c70f0dc13a2 437 Gene3D G3DSA:2.30.330.10 358 430 4.2E-16 T 06-07-2017 CAL12_RS22060 1f93aa4c50753eb8d4815c70f0dc13a2 437 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 360 427 2.5E-14 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS20475 9af0185b2bfd5ef0837aa4b1cfe18d16 222 SUPERFAMILY SSF54909 1 99 5.81E-17 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS20475 9af0185b2bfd5ef0837aa4b1cfe18d16 222 Gene3D G3DSA:3.30.70.900 1 98 1.3E-11 T 06-07-2017 CAL12_RS20475 9af0185b2bfd5ef0837aa4b1cfe18d16 222 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 72 5.5E-7 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 SUPERFAMILY SSF53623 481 715 2.09E-30 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 7 867 0.0 T 06-07-2017 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Pfam PF02875 Mur ligase family, glutamate ligase domain 731 796 1.5E-8 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.90.190.20 726 850 5.7E-21 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 219 305 3.9E-8 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 SUPERFAMILY SSF56059 219 494 3.18E-34 T 06-07-2017 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Pfam PF08245 Mur ligase middle domain 486 698 5.9E-12 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.30.470.20 227 307 4.3E-21 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.40.1190.10 480 715 1.4E-29 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.30.470.20 308 339 2.0E-4 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.30.470.20 392 451 2.0E-4 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 Gene3D G3DSA:3.30.470.20 211 226 2.0E-4 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19115 beee8ed82986e650a0a6e2f0688f2289 871 SUPERFAMILY SSF53244 729 850 2.38E-20 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Gene3D G3DSA:3.40.120.10 176 253 5.8E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 370 9.1E-20 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 11 129 6.7E-29 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 392 454 3.7E-11 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 SUPERFAMILY SSF53738 9 134 1.77E-34 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 257 3.6E-27 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Gene3D G3DSA:3.30.310.50 373 463 2.6E-25 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 SUPERFAMILY SSF53738 261 358 3.41E-30 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Gene3D G3DSA:3.40.120.10 255 370 3.1E-41 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 SUPERFAMILY SSF55957 370 465 3.92E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 1.2E-23 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.2E-23 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 1.2E-23 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 1.2E-23 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 SUPERFAMILY SSF53738 157 259 5.1E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 Gene3D G3DSA:3.40.120.10 8 131 6.0E-31 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS02710 2d8f02f2f68b2be0d08de1f985edae4b 465 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 Pfam PF00994 Probable molybdopterin binding domain 20 162 2.4E-28 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 81 94 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 SUPERFAMILY SSF53218 16 204 6.94E-46 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 SMART SM00852 19 169 1.5E-22 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 18 162 1.3E-35 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05040 c7e38d89aed9c767f2bfbfea0e85f668 208 Gene3D G3DSA:3.40.980.10 16 204 4.5E-50 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05725 00e042a8605a78254533bb1d404aa43b 271 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 25 238 8.0E-20 T 06-07-2017 CAL12_RS05875 b6191748a4bc46b58fac4d3e24a902f0 258 SUPERFAMILY SSF161098 52 237 1.1E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05875 b6191748a4bc46b58fac4d3e24a902f0 258 Gene3D G3DSA:1.10.3720.10 32 232 1.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05875 b6191748a4bc46b58fac4d3e24a902f0 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 244 3.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01660 dbf1bdc89bc59c0b9b53728cf6660e15 247 SMART SM00749 133 196 0.0015 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAL12_RS01660 dbf1bdc89bc59c0b9b53728cf6660e15 247 SMART SM00749 56 118 16.0 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAL12_RS01660 dbf1bdc89bc59c0b9b53728cf6660e15 247 Pfam PF04972 BON domain 128 190 1.8E-14 T 06-07-2017 IPR007055 BON domain CAL12_RS01660 dbf1bdc89bc59c0b9b53728cf6660e15 247 Pfam PF04972 BON domain 70 119 1.1E-11 T 06-07-2017 IPR007055 BON domain CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 Pfam PF01175 Urocanase 15 549 2.3E-261 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 Gene3D G3DSA:3.40.1770.10 11 144 1.8E-160 T 06-07-2017 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 Gene3D G3DSA:3.40.1770.10 363 558 1.8E-160 T 06-07-2017 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 TIGRFAM TIGR01228 hutU: urocanate hydratase 13 557 3.2E-294 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 Gene3D G3DSA:3.40.50.10730 145 352 4.2E-93 T 06-07-2017 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 Hamap MF_00577 Urocanate hydratase [hutU]. 5 559 50.116 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 SUPERFAMILY SSF111326 8 559 1.44E-261 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 ProSitePatterns PS01233 Urocanase signature. 445 460 - T 06-07-2017 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS16070 8608c2e58c2e11ec9ddd8a8fbd9d6537 560 PIRSF PIRSF001423 1 560 2.2E-294 T 06-07-2017 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CAL12_RS15560 95776fd9f86f783f951f50b5dbaa89da 134 Pfam PF07681 DoxX 9 88 7.3E-18 T 06-07-2017 IPR032808 DoxX family CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Pfam PF01709 Transcriptional regulator 5 236 1.3E-94 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.491 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Gene3D G3DSA:3.30.70.980 135 203 1.6E-23 T 06-07-2017 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Gene3D G3DSA:1.10.10.200 1 80 2.7E-37 T 06-07-2017 IPR017856 Integrase, N-terminal zinc-binding domain-like CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Gene3D G3DSA:3.30.1270.10 212 241 2.6E-37 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 Gene3D G3DSA:3.30.1270.10 82 134 2.6E-37 T 06-07-2017 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 4.2E-92 T 06-07-2017 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS17865 40c07d8a46f12a48e758012f89bb4a85 244 SUPERFAMILY SSF75625 3 240 7.32E-94 T 06-07-2017 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 Gene3D G3DSA:3.40.50.620 6 134 2.0E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 SUPERFAMILY SSF52402 7 139 3.35E-24 T 06-07-2017 CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 Gene3D G3DSA:3.40.50.620 135 279 1.8E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 SUPERFAMILY SSF52402 144 279 2.02E-25 T 06-07-2017 CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 PRINTS PR01438 Universal stress protein signature 144 162 5.2E-13 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 PRINTS PR01438 Universal stress protein signature 255 277 5.2E-13 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 PRINTS PR01438 Universal stress protein signature 237 249 5.2E-13 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 Pfam PF00582 Universal stress protein family 7 137 2.2E-22 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS25340 332ab0fd177637405d3b1e69fa3931a2 281 Pfam PF00582 Universal stress protein family 144 277 9.1E-23 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 442 1.1E-37 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 SMART SM00878 336 441 7.2E-63 T 06-07-2017 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 SUPERFAMILY SSF52440 1 113 2.16E-49 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 3.3E-80 T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Gene3D G3DSA:3.30.1490.20 130 203 1.8E-28 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 2.2E-223 T 06-07-2017 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Gene3D G3DSA:3.30.470.20 204 444 1.2E-95 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 SUPERFAMILY SSF51246 331 443 1.57E-42 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.9E-46 T 06-07-2017 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 Gene3D G3DSA:3.40.50.20 1 129 7.0E-53 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 06-07-2017 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CAL12_RS24865 bc456db4830b06aa01ec5c85373682d6 448 SUPERFAMILY SSF56059 83 347 5.3E-70 T 06-07-2017 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 Gene3D G3DSA:1.10.10.10 1 86 7.3E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 SUPERFAMILY SSF53850 91 289 9.0E-33 T 06-07-2017 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 Gene3D G3DSA:3.40.190.10 91 176 4.0E-16 T 06-07-2017 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 SUPERFAMILY SSF46785 1 110 9.3E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 Pfam PF03466 LysR substrate binding domain 91 288 2.6E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 Gene3D G3DSA:3.40.190.10 177 259 2.3E-17 T 06-07-2017 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26290 022516606b372d6050bc8410ea2b2476 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 2.4E-164 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 SUPERFAMILY SSF51246 330 423 1.05E-29 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 99 1.8E-36 T 06-07-2017 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 SMART SM01209 100 297 3.2E-132 T 06-07-2017 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 41.865 T 06-07-2017 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Gene3D G3DSA:3.30.1490.20 118 187 2.9E-32 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 SUPERFAMILY SSF56059 101 320 9.02E-61 T 06-07-2017 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 332 421 2.6E-28 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 SMART SM01210 331 423 1.0E-51 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Gene3D G3DSA:3.90.600.10 332 422 1.6E-33 T 06-07-2017 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 100 297 2.8E-75 T 06-07-2017 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 SUPERFAMILY SSF52440 1 100 2.16E-34 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Gene3D G3DSA:3.40.50.20 2 92 2.0E-35 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS17870 bf06cfc9d94259945b5b987d4894c519 434 Gene3D G3DSA:3.30.470.20 189 329 1.2E-57 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 Gene3D G3DSA:3.40.190.10 178 262 7.1E-19 T 06-07-2017 CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 Gene3D G3DSA:3.40.190.10 92 177 1.9E-20 T 06-07-2017 CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 SUPERFAMILY SSF53850 90 297 9.05E-41 T 06-07-2017 CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 Gene3D G3DSA:1.10.10.10 6 83 4.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 6.6E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 SUPERFAMILY SSF46785 6 112 4.15E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00070 7f755502c312be0412c527007d7cc6da 301 Pfam PF03466 LysR substrate binding domain 89 294 5.5E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 SUPERFAMILY SSF46785 4 84 1.41E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.0E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 Gene3D G3DSA:3.40.190.10 93 178 7.5E-17 T 06-07-2017 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 SUPERFAMILY SSF53850 94 297 1.45E-34 T 06-07-2017 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.6E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 Gene3D G3DSA:1.10.10.10 4 83 4.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 Pfam PF03466 LysR substrate binding domain 92 293 1.0E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS09795 f7f9e2f4db3354aa4bf3dc47cfe500ec 299 Gene3D G3DSA:3.40.190.10 179 265 1.9E-21 T 06-07-2017 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 Gene3D G3DSA:3.20.20.70 18 395 1.4E-145 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 Pfam PF00682 HMGL-like 34 312 1.6E-78 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 244 257 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 SUPERFAMILY SSF110921 454 553 3.01E-31 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 553 1.5E-239 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 Pfam PF08502 LeuA allosteric (dimerisation) domain 423 553 3.1E-26 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 41 57 - T 06-07-2017 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 SUPERFAMILY SSF51569 23 331 4.76E-101 T 06-07-2017 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 SUPERFAMILY SSF89000 389 439 6.28E-15 T 06-07-2017 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 555 53.4 T 06-07-2017 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS00650 ff015b186f0c973b3dd789d394761f69 570 SMART SM00917 423 554 5.5E-29 T 06-07-2017 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 Pfam PF13394 4Fe-4S single cluster domain 25 121 9.2E-6 T 06-07-2017 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 210 32.574 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 PIRSF PIRSF000370 1 210 4.9E-37 T 06-07-2017 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 Pfam PF04055 Radical SAM superfamily 45 128 1.6E-7 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 Gene3D G3DSA:3.20.20.70 45 132 5.8E-10 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 SUPERFAMILY SSF102114 45 136 2.09E-9 T 06-07-2017 CAL12_RS16005 d095296bed0d483413205933e9ebe09c 210 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 210 6.2E-109 T 06-07-2017 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CAL12_RS01355 f2b1678a27e1310da123bcbec078f376 252 SUPERFAMILY SSF161098 3 245 1.28E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01355 f2b1678a27e1310da123bcbec078f376 252 Gene3D G3DSA:1.10.3720.10 3 242 8.5E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01355 f2b1678a27e1310da123bcbec078f376 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 62 248 1.7E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 SUPERFAMILY SSF56645 2 225 4.19E-71 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 215 2.9E-23 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Gene3D G3DSA:2.40.110.10 120 215 1.9E-35 T 06-07-2017 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 SUPERFAMILY SSF47203 246 378 6.73E-49 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 248 376 2.8E-45 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Gene3D G3DSA:1.10.540.10 2 116 7.4E-29 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Gene3D G3DSA:1.20.140.10 216 377 2.1E-55 T 06-07-2017 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 PIRSF PIRSF016578 2 375 3.1E-31 T 06-07-2017 CAL12_RS24595 61d1610189856fcecb9c02665acce711 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 2.0E-27 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 SUPERFAMILY SSF46689 3 75 4.05E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 5 50 5.2E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 16 46 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 Gene3D G3DSA:1.10.357.10 58 185 8.9E-27 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 4 17 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 48 2.0E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 SUPERFAMILY SSF48498 70 184 1.83E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16495 fc663c4b354f3a8cc9d8db5cc72b2ba7 192 Gene3D G3DSA:1.10.10.60 3 57 4.0E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 161 321 1.9E-49 T 06-07-2017 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 SMART SM00363 94 152 1.8E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 SUPERFAMILY SSF55120 155 324 3.84E-39 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 195 209 - T 06-07-2017 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 Pfam PF00849 RNA pseudouridylate synthase 157 290 8.7E-15 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 Gene3D G3DSA:3.10.290.10 96 149 5.0E-16 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 SUPERFAMILY SSF55174 80 186 2.83E-16 T 06-07-2017 CAL12_RS18445 de81d05749fcaaaf832d0ce6fda444fe 577 Pfam PF01479 S4 domain 96 139 1.5E-9 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 261 1.9E-26 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 Pfam PF00460 Flagella basal body rod protein 5 35 7.0E-12 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 SUPERFAMILY SSF117143 92 223 4.05E-36 T 06-07-2017 CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 244 5.3E-33 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 3.0E-43 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 6.2E-109 T 06-07-2017 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 CAL12_RS11915 a03d05024eea7f7159a90dc15193d730 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 Pfam PF03797 Autotransporter beta-domain 693 957 5.7E-47 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 SUPERFAMILY SSF103515 638 971 7.72E-62 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 443 971 2.9E-42 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 SUPERFAMILY SSF51126 248 522 2.98E-16 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 Gene3D G3DSA:2.40.128.130 661 971 3.0E-63 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23415 0748278dccd78b3680b5c739b5840883 971 SMART SM00869 694 961 7.9E-41 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 SUPERFAMILY SSF56176 1 175 2.07E-49 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 Gene3D G3DSA:3.30.390.50 180 288 2.8E-26 T 06-07-2017 CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 176 3.9E-46 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 SUPERFAMILY SSF55447 180 285 2.49E-22 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 Gene3D G3DSA:3.30.465.10 57 175 5.4E-32 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 SMART SM01092 182 283 2.3E-24 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 282 8.6E-19 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS03285 c8a8bde605f0c9cad8d01abd7bfe7325 296 Gene3D G3DSA:3.30.43.10 1 53 1.9E-16 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 Pfam PF13377 Periplasmic binding protein-like domain 181 341 1.8E-29 T 06-07-2017 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 9.1E-15 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 SMART SM00354 13 83 1.3E-20 T 06-07-2017 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 SUPERFAMILY SSF53822 70 329 6.28E-53 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 Gene3D G3DSA:3.40.50.2300 73 181 1.2E-28 T 06-07-2017 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 Gene3D G3DSA:3.40.50.2300 182 341 2.7E-45 T 06-07-2017 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 Gene3D G3DSA:1.10.260.40 14 72 3.4E-21 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 06-07-2017 CAL12_RS00960 1bbc06b1e43c8ca705e80c95f547dccc 341 SUPERFAMILY SSF47413 14 71 2.89E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 SUPERFAMILY SSF161098 374 564 3.01E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 Gene3D G3DSA:1.10.3720.10 65 256 2.5E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 Gene3D G3DSA:1.10.3720.10 376 566 2.9E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 256 2.6E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 393 569 1.6E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12355 9d631d39978eefeeb6d22d2818cdb1c7 577 SUPERFAMILY SSF161098 63 259 9.42E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 205 435 1.0E-43 T 06-07-2017 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal Reactome: R-HSA-75105 CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 SUPERFAMILY SSF53474 335 392 4.9E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 SUPERFAMILY SSF53474 74 302 4.9E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 SUPERFAMILY SSF53474 422 433 4.9E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 22 142 3.2E-20 T 06-07-2017 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 Gene3D G3DSA:3.40.50.1820 142 262 1.5E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 Gene3D G3DSA:3.40.50.1820 330 433 1.5E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12960 213eaa721031ab4b533569e696a5ae9b 443 PIRSF PIRSF016521 8 441 4.5E-94 T 06-07-2017 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 06-07-2017 IPR020081 SsrA-binding protein, conserved site CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 SUPERFAMILY SSF74982 3 127 7.59E-48 T 06-07-2017 IPR023620 Small protein B CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 Gene3D G3DSA:2.40.280.10 3 122 2.7E-47 T 06-07-2017 IPR023620 Small protein B CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 3.3E-51 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 69.711 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 Pfam PF01668 SmpB protein 3 65 2.0E-28 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAL12_RS12230 e29eed4386a529fe727f496f3567a9e2 156 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 5.0E-59 T 06-07-2017 IPR000037 SsrA-binding protein GO:0003723 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Gene3D G3DSA:1.20.140.10 223 387 1.4E-55 T 06-07-2017 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 366 8.9E-38 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 SUPERFAMILY SSF47203 231 386 2.42E-47 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Gene3D G3DSA:1.10.540.10 3 119 1.0E-33 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Gene3D G3DSA:2.40.110.10 122 222 1.1E-30 T 06-07-2017 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 3.6E-21 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.1E-24 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS25680 f8952cca2f8354b81c96d775d6ff3dc1 388 SUPERFAMILY SSF56645 1 232 2.49E-65 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Gene3D G3DSA:3.40.50.740 359 462 9.1E-38 T 06-07-2017 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Gene3D G3DSA:3.40.50.740 55 153 9.1E-38 T 06-07-2017 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Gene3D G3DSA:3.90.55.10 463 564 4.0E-31 T 06-07-2017 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Pfam PF01568 Molydopterin dinucleotide binding domain 629 746 3.4E-25 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 668 695 - T 06-07-2017 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 SUPERFAMILY SSF50692 621 771 2.87E-39 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Gene3D G3DSA:3.40.228.10 154 358 7.5E-46 T 06-07-2017 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 SUPERFAMILY SSF53706 32 630 1.96E-148 T 06-07-2017 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Pfam PF00384 Molybdopterin oxidoreductase 60 517 3.0E-60 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS14850 84960d33d8ae738d3b63de05af746dbb 783 Gene3D G3DSA:2.40.40.20 607 767 1.0E-44 T 06-07-2017 CAL12_RS02260 3694b40e65d4c3dca20c68f2af79c34a 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 4 67 3.9E-23 T 06-07-2017 IPR010035 ThiS, thiamine-biosynthesis CAL12_RS02260 3694b40e65d4c3dca20c68f2af79c34a 67 Gene3D G3DSA:3.10.20.30 3 67 3.2E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS02260 3694b40e65d4c3dca20c68f2af79c34a 67 SUPERFAMILY SSF54285 3 66 2.18E-19 T 06-07-2017 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CAL12_RS02260 3694b40e65d4c3dca20c68f2af79c34a 67 Pfam PF02597 ThiS family 4 67 3.2E-15 T 06-07-2017 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CAL12_RS03350 6ad6fce4c9539efcba6afbace01cc0d4 235 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03350 6ad6fce4c9539efcba6afbace01cc0d4 235 SUPERFAMILY SSF52540 1 221 1.31E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03350 6ad6fce4c9539efcba6afbace01cc0d4 235 Gene3D G3DSA:3.40.50.300 1 221 1.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03350 6ad6fce4c9539efcba6afbace01cc0d4 235 Pfam PF00005 ABC transporter 17 164 9.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03350 6ad6fce4c9539efcba6afbace01cc0d4 235 SMART SM00382 26 213 6.3E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.6E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 SUPERFAMILY SSF46785 4 80 3.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 Gene3D G3DSA:3.40.190.10 193 258 4.2E-10 T 06-07-2017 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 Gene3D G3DSA:3.40.190.10 89 192 1.7E-14 T 06-07-2017 CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 Gene3D G3DSA:1.10.10.10 3 80 1.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 Pfam PF03466 LysR substrate binding domain 88 278 8.3E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15930 36f8f03de16774b0f5b9843ee8224d29 299 SUPERFAMILY SSF53850 89 277 2.02E-25 T 06-07-2017 CAL12_RS17955 b935b3ea521c299a0976a5ff48266431 254 Pfam PF02698 DUF218 domain 79 244 6.2E-32 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAL12_RS17955 b935b3ea521c299a0976a5ff48266431 254 Gene3D G3DSA:3.40.50.620 73 212 3.1E-31 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS26410 b0430fd81ae416119177f88bf34824ff 273 Gene3D G3DSA:3.40.50.300 8 250 1.0E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26410 b0430fd81ae416119177f88bf34824ff 273 SUPERFAMILY SSF52540 9 249 2.38E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26410 b0430fd81ae416119177f88bf34824ff 273 Pfam PF00005 ABC transporter 27 178 7.8E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26410 b0430fd81ae416119177f88bf34824ff 273 SMART SM00382 36 228 6.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04290 5a5c304a395160e82372965c5bbd01cf 468 Pfam PF07690 Major Facilitator Superfamily 19 408 1.8E-49 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS04290 5a5c304a395160e82372965c5bbd01cf 468 Gene3D G3DSA:1.20.1250.20 15 193 1.5E-28 T 06-07-2017 CAL12_RS04290 5a5c304a395160e82372965c5bbd01cf 468 SUPERFAMILY SSF103473 11 194 1.96E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS04290 5a5c304a395160e82372965c5bbd01cf 468 SUPERFAMILY SSF103473 246 449 1.96E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS04290 5a5c304a395160e82372965c5bbd01cf 468 Gene3D G3DSA:1.20.1250.20 263 448 9.2E-13 T 06-07-2017 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Gene3D G3DSA:3.30.365.10 315 376 4.4E-7 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Gene3D G3DSA:3.30.365.10 424 586 7.8E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Gene3D G3DSA:3.30.365.10 587 781 2.9E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 SUPERFAMILY SSF56003 346 780 7.68E-105 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Gene3D G3DSA:3.90.1170.50 224 314 1.2E-18 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS01110 a5978b79c92120f575769759007537b0 810 PIRSF PIRSF036389 66 779 2.7E-181 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 347 591 3.7E-27 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 636 725 1.5E-11 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 73 183 3.0E-19 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 SUPERFAMILY SSF56003 71 266 1.07E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 Gene3D G3DSA:3.30.365.10 73 223 4.8E-34 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS01110 a5978b79c92120f575769759007537b0 810 SMART SM01008 240 326 1.9E-16 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS01110 a5978b79c92120f575769759007537b0 810 SUPERFAMILY SSF54665 241 327 3.71E-7 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 SUPERFAMILY SSF49785 321 529 5.74E-46 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 295 523 6.0E-47 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 15 264 1.5E-59 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 182 529 4.6E-50 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 11 155 1.0E-45 T 06-07-2017 IPR005674 CocE/Serine esterase GO:0016787 CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 SUPERFAMILY SSF53474 3 330 1.73E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 SMART SM00939 283 525 1.5E-66 T 06-07-2017 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 Gene3D G3DSA:2.60.120.260 328 532 1.3E-53 T 06-07-2017 IPR008979 Galactose-binding domain-like CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 Gene3D G3DSA:3.40.50.1820 7 149 8.9E-81 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03730 7becb8624d59cf3cb77f2d072d9798aa 658 Gene3D G3DSA:3.40.50.1820 208 310 8.9E-81 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS22675 44761637d45ba7e2be60098cd6b1d156 463 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 461 6.2E-144 T 06-07-2017 IPR010263 Type VI secretion protein, VC_A0114 CAL12_RS22675 44761637d45ba7e2be60098cd6b1d156 463 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 5 463 4.9E-141 T 06-07-2017 IPR010263 Type VI secretion protein, VC_A0114 CAL12_RS03270 c33934df864d9a25a6b1f104d8bb5c3d 268 Gene3D G3DSA:3.30.530.20 2 145 5.2E-32 T 06-07-2017 IPR023393 START-like domain CAL12_RS03270 c33934df864d9a25a6b1f104d8bb5c3d 268 SUPERFAMILY SSF55961 2 139 6.87E-26 T 06-07-2017 CAL12_RS03270 c33934df864d9a25a6b1f104d8bb5c3d 268 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 2 138 1.8E-11 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.3E-13 T 06-07-2017 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 4.3E-13 T 06-07-2017 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 4.3E-13 T 06-07-2017 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 Pfam PF01494 FAD binding domain 7 323 1.5E-11 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 SUPERFAMILY SSF51905 6 183 4.04E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 SUPERFAMILY SSF51905 275 387 4.04E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 Gene3D G3DSA:3.50.50.60 3 186 6.4E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 Gene3D G3DSA:3.50.50.60 277 316 6.4E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 06-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS05605 fc6016c579b279f0501de26883bb7757 392 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 8 387 6.2E-81 T 06-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS04945 0f646774be5da2b26dc264a7d35a906d 212 SUPERFAMILY SSF53271 3 206 8.26E-63 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS04945 0f646774be5da2b26dc264a7d35a906d 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 2.7E-82 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAL12_RS04945 0f646774be5da2b26dc264a7d35a906d 212 Gene3D G3DSA:3.40.50.2020 3 207 4.5E-71 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS04945 0f646774be5da2b26dc264a7d35a906d 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 42.564 T 06-07-2017 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CAL12_RS04945 0f646774be5da2b26dc264a7d35a906d 212 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 2.7E-63 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS16925 010847c4350d2c8833a5168841772462 298 Gene3D G3DSA:1.10.1040.10 180 292 3.9E-22 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS16925 010847c4350d2c8833a5168841772462 298 Gene3D G3DSA:3.40.50.720 6 179 4.9E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16925 010847c4350d2c8833a5168841772462 298 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 8 293 4.2E-43 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS16925 010847c4350d2c8833a5168841772462 298 SUPERFAMILY SSF48179 172 292 1.9E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS16925 010847c4350d2c8833a5168841772462 298 SUPERFAMILY SSF51735 8 121 8.23E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16925 010847c4350d2c8833a5168841772462 298 Pfam PF02558 Ketopantoate reductase PanE/ApbA 9 151 9.2E-27 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS16925 010847c4350d2c8833a5168841772462 298 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 292 5.1E-19 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 SUPERFAMILY SSF69118 1 175 1.22E-44 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 3 160 4.7E-24 T 06-07-2017 IPR010195 Uncharacterised peroxidase-related CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 103 1.1E-10 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 89 1.9E-10 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 Gene3D G3DSA:1.20.1290.10 137 174 2.8E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS16895 33e3903a46ec7900011ec759e16e7779 185 Gene3D G3DSA:1.20.1290.10 1 87 2.8E-32 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS17930 b70f3e54aac561c9a9bd42b072204dbb 494 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 20 431 9.7E-151 T 06-07-2017 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CAL12_RS17930 b70f3e54aac561c9a9bd42b072204dbb 494 SUPERFAMILY SSF50249 46 131 9.28E-18 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17930 b70f3e54aac561c9a9bd42b072204dbb 494 Gene3D G3DSA:2.40.50.140 38 131 2.2E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17930 b70f3e54aac561c9a9bd42b072204dbb 494 SMART SM00316 44 125 5.5E-10 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS17930 b70f3e54aac561c9a9bd42b072204dbb 494 Pfam PF10150 Ribonuclease E/G family 127 398 2.0E-98 T 06-07-2017 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CAL12_RS13960 88d34d474377dfe2f0bea0e5fe44bd74 342 SUPERFAMILY SSF53850 135 299 6.74E-16 T 06-07-2017 CAL12_RS13960 88d34d474377dfe2f0bea0e5fe44bd74 342 Gene3D G3DSA:3.40.190.10 146 260 5.0E-5 T 06-07-2017 CAL12_RS13960 88d34d474377dfe2f0bea0e5fe44bd74 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 68 336 3.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13960 88d34d474377dfe2f0bea0e5fe44bd74 342 PIRSF PIRSF017082 13 342 7.0E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01590 1c2aa046e401a434e611b62d49819c81 569 Pfam PF02538 Hydantoinase B/oxoprolinase 13 537 1.3E-167 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS19995 8194dc1ea47656cf4aa2a578054c46cd 261 Pfam PF07103 Protein of unknown function (DUF1365) 5 253 7.0E-71 T 06-07-2017 IPR010775 Protein of unknown function DUF1365 CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 373 2.8E-125 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 SUPERFAMILY SSF50331 251 373 8.5E-18 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 SUPERFAMILY SSF52540 18 256 1.24E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 Gene3D G3DSA:3.40.50.300 10 250 1.9E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 Pfam PF08402 TOBE domain 293 373 2.5E-14 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 Pfam PF00005 ABC transporter 34 175 2.8E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS18065 823d10ea9ec0501079b00461424e236b 375 SMART SM00382 42 230 1.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25840 834bc277d5da53ef9d052f528c161730 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 1.2E-83 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS25840 834bc277d5da53ef9d052f528c161730 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS25840 834bc277d5da53ef9d052f528c161730 258 Gene3D G3DSA:3.90.226.10 2 256 6.3E-101 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS25840 834bc277d5da53ef9d052f528c161730 258 SUPERFAMILY SSF52096 2 257 6.74E-92 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 265 272 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 Pfam PF00171 Aldehyde dehydrogenase family 29 493 5.3E-184 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 Gene3D G3DSA:3.40.605.10 21 279 8.5E-100 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 SUPERFAMILY SSF53720 16 497 5.24E-178 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS20115 0702624b68820ecce315d83d22f7210e 509 Gene3D G3DSA:3.40.309.10 280 458 3.7E-75 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 ProSitePatterns PS00482 Dihydroorotase signature 1. 16 24 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 PIRSF PIRSF001237 5 354 1.6E-134 T 06-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 SUPERFAMILY SSF51556 7 352 1.36E-139 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 Pfam PF01979 Amidohydrolase family 16 319 8.7E-22 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 Gene3D G3DSA:3.20.20.140 7 353 4.0E-130 T 06-07-2017 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 10 353 5.7E-140 T 06-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 Hamap MF_00219 Dihydroorotase [pyrC]. 7 353 44.799 T 06-07-2017 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS22475 b0b2ee04e4d32493081495cb4b4e247a 354 ProSitePatterns PS00483 Dihydroorotase signature 2. 255 266 - T 06-07-2017 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 Gene3D G3DSA:2.60.120.580 213 281 2.9E-65 T 06-07-2017 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 Gene3D G3DSA:2.60.120.580 147 164 2.9E-65 T 06-07-2017 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 Gene3D G3DSA:2.60.120.580 7 94 2.9E-65 T 06-07-2017 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 SUPERFAMILY SSF141130 213 383 6.28E-78 T 06-07-2017 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 SUPERFAMILY SSF141130 16 164 6.28E-78 T 06-07-2017 CAL12_RS03815 d485bb2a3ac894e299f1a01ee5ce573a 409 Pfam PF03069 Acetamidase/Formamidase family 7 384 4.0E-176 T 06-07-2017 IPR004304 Acetamidase/Formamidase GO:0016811 CAL12_RS18890 2b69847ed3cf68e397e559121c8a7d67 175 Pfam PF12836 Helix-hairpin-helix motif 63 118 1.0E-14 T 06-07-2017 CAL12_RS18890 2b69847ed3cf68e397e559121c8a7d67 175 Gene3D G3DSA:1.10.150.280 60 121 7.6E-17 T 06-07-2017 CAL12_RS18890 2b69847ed3cf68e397e559121c8a7d67 175 SUPERFAMILY SSF47781 63 127 1.06E-16 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS18890 2b69847ed3cf68e397e559121c8a7d67 175 SMART SM00278 101 121 550.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS18890 2b69847ed3cf68e397e559121c8a7d67 175 SMART SM00278 71 90 0.17 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS04280 58fb9bef079bf9ce44c87cb288661e86 341 Pfam PF13379 NMT1-like family 93 260 4.2E-9 T 06-07-2017 CAL12_RS04280 58fb9bef079bf9ce44c87cb288661e86 341 SUPERFAMILY SSF53850 77 336 5.69E-26 T 06-07-2017 CAL12_RS04280 58fb9bef079bf9ce44c87cb288661e86 341 Gene3D G3DSA:3.40.190.10 131 218 1.5E-14 T 06-07-2017 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 06-07-2017 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00385 P450 superfamily signature 350 361 1.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00385 P450 superfamily signature 273 284 1.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00385 P450 superfamily signature 341 350 1.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00385 P450 superfamily signature 238 255 1.3E-5 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 85 96 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 341 350 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 131 147 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 148 163 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 192 214 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 350 361 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 318 333 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 290 317 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 PRINTS PR00359 B-class P450 signature 273 284 1.3E-46 T 06-07-2017 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 Pfam PF00067 Cytochrome P450 174 259 1.4E-8 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 Pfam PF00067 Cytochrome P450 269 370 1.6E-19 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 SUPERFAMILY SSF48264 9 398 1.57E-92 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS01485 d09bd9ecf3a98f4641a6edd957809608 400 Gene3D G3DSA:1.10.630.10 5 399 5.7E-116 T 06-07-2017 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CAL12_RS20505 48293564fd582d5844b3d521d80e45b6 376 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 350 7.2E-91 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS20505 48293564fd582d5844b3d521d80e45b6 376 Gene3D G3DSA:3.20.20.70 6 373 2.3E-125 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS20505 48293564fd582d5844b3d521d80e45b6 376 SUPERFAMILY SSF51395 7 372 2.15E-115 T 06-07-2017 CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 Gene3D G3DSA:1.10.1660.10 24 130 1.3E-25 T 06-07-2017 CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 ProSitePatterns PS00552 MerR-type HTH domain signature. 24 46 - T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 SUPERFAMILY SSF46955 22 123 3.3E-22 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 Gene3D G3DSA:3.40.50.300 241 313 8.4E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 SMART SM00422 21 89 5.7E-17 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 Pfam PF13411 MerR HTH family regulatory protein 23 87 2.6E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 SUPERFAMILY SSF52540 172 350 1.35E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00045 77c524e4f5c211667ab4598cd407fc53 354 Gene3D G3DSA:3.40.50.300 171 234 2.3E-4 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04080 ff11143f82f946d4283a907cc38ea9cf 322 PIRSF PIRSF017082 1 322 1.1E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04080 ff11143f82f946d4283a907cc38ea9cf 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 3.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04080 ff11143f82f946d4283a907cc38ea9cf 322 SUPERFAMILY SSF53850 112 284 3.1E-11 T 06-07-2017 CAL12_RS18780 b24f9cc13d1e6c5b7bbe1075ae4ea86e 282 Pfam PF01039 Carboxyl transferase domain 17 202 6.5E-13 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS18780 b24f9cc13d1e6c5b7bbe1075ae4ea86e 282 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 12 280 1.5E-113 T 06-07-2017 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 CAL12_RS18780 b24f9cc13d1e6c5b7bbe1075ae4ea86e 282 SUPERFAMILY SSF52096 15 233 2.81E-35 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18780 b24f9cc13d1e6c5b7bbe1075ae4ea86e 282 Gene3D G3DSA:3.90.226.10 15 242 3.7E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Gene3D G3DSA:3.30.300.30 869 997 3.3E-30 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1016 1031 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 ProSitePatterns PS00455 Putative AMP-binding domain signature. 614 625 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 488 898 1.5E-102 T 06-07-2017 IPR010071 Amino acid adenylation domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Pfam PF13193 AMP-binding enzyme C-terminal domain 882 963 1.9E-6 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Pfam PF00501 AMP-binding enzyme 469 874 8.2E-77 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Pfam PF00668 Condensation domain 18 313 1.7E-20 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 SUPERFAMILY SSF47336 986 1057 2.36E-18 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Pfam PF00550 Phosphopantetheine attachment site 995 1056 4.0E-13 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Gene3D G3DSA:1.10.1200.10 998 1060 3.2E-22 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 SUPERFAMILY SSF56801 429 976 1.15E-123 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 SUPERFAMILY SSF52777 17 199 3.89E-21 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Gene3D G3DSA:3.40.50.980 461 623 1.8E-38 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Gene3D G3DSA:3.40.50.980 624 768 4.6E-33 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 Gene3D G3DSA:2.30.38.10 790 862 3.4E-15 T 06-07-2017 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 SMART SM00823 Phosphopantetheine attachment site 992 1061 1.0E-11 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11045 4f30774c1345abe8e3d8647fd64e0269 1096 SUPERFAMILY SSF52777 187 432 4.5E-26 T 06-07-2017 CAL12_RS05970 3eb50b4ec4e56a918da0d2763372917e 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 1.4E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05970 3eb50b4ec4e56a918da0d2763372917e 323 PIRSF PIRSF017082 1 323 5.0E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05970 3eb50b4ec4e56a918da0d2763372917e 323 SUPERFAMILY SSF53850 111 287 1.69E-13 T 06-07-2017 CAL12_RS10485 6a9ab415f4bbbe07326c4a4d34448b91 293 SUPERFAMILY SSF161098 30 278 5.33E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10485 6a9ab415f4bbbe07326c4a4d34448b91 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 286 6.0E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10485 6a9ab415f4bbbe07326c4a4d34448b91 293 Gene3D G3DSA:1.10.3720.10 25 287 1.8E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Gene3D G3DSA:1.10.287.130 136 197 1.1E-13 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Gene3D G3DSA:3.30.565.10 202 369 1.5E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SUPERFAMILY SSF52172 440 559 3.42E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SUPERFAMILY SSF55874 190 364 3.01E-40 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Pfam PF00072 Response regulator receiver domain 444 553 6.7E-15 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 248 361 8.2E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SMART SM00388 136 201 2.6E-20 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Gene3D G3DSA:3.40.50.2300 440 560 1.3E-26 T 06-07-2017 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SUPERFAMILY SSF47226 538 550 6.36E-7 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SUPERFAMILY SSF47226 578 674 6.36E-7 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SMART SM00387 248 366 1.8E-35 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SUPERFAMILY SSF47384 123 202 8.63E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 Pfam PF00512 His Kinase A (phospho-acceptor) domain 137 200 4.0E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 SMART SM00448 441 554 8.2E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 342 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 303 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS12440 b1b5366023c89ac613fa285a4b3a3063 689 PRINTS PR00344 Bacterial sensor protein C-terminal signature 307 317 2.7E-11 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS13990 3efcd3c1c10333d759243f1ebddb8db4 335 SUPERFAMILY SSF53850 123 295 2.58E-11 T 06-07-2017 CAL12_RS13990 3efcd3c1c10333d759243f1ebddb8db4 335 PIRSF PIRSF017082 1 334 9.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13990 3efcd3c1c10333d759243f1ebddb8db4 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 59 331 1.4E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04045 d383fa3601f0aa4daf84c78eeddf1220 445 Gene3D G3DSA:3.40.190.10 270 325 1.2E-31 T 06-07-2017 CAL12_RS04045 d383fa3601f0aa4daf84c78eeddf1220 445 Gene3D G3DSA:3.40.190.10 5 129 1.2E-31 T 06-07-2017 CAL12_RS04045 d383fa3601f0aa4daf84c78eeddf1220 445 Gene3D G3DSA:3.40.190.10 134 269 1.9E-25 T 06-07-2017 CAL12_RS04045 d383fa3601f0aa4daf84c78eeddf1220 445 Pfam PF13343 Bacterial extracellular solute-binding protein 79 297 7.5E-26 T 06-07-2017 CAL12_RS04045 d383fa3601f0aa4daf84c78eeddf1220 445 SUPERFAMILY SSF53850 26 320 6.92E-51 T 06-07-2017 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 SMART SM00421 229 286 1.4E-17 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 SUPERFAMILY SSF46894 226 288 1.19E-16 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 Pfam PF00196 Bacterial regulatory proteins, luxR family 231 284 5.3E-15 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 262 274 4.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 246 262 4.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 246 4.2E-10 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 Gene3D G3DSA:1.10.10.10 230 288 2.9E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12925 f7820559d62d4b9d1ae4d725500ab7f3 302 ProSitePatterns PS00622 LuxR-type HTH domain signature. 246 273 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 SMART SM00448 1 112 6.8E-38 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 Gene3D G3DSA:1.10.10.10 123 216 7.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 Pfam PF00072 Response regulator receiver domain 3 112 3.2E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 SUPERFAMILY SSF52172 1 174 1.18E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 Gene3D G3DSA:3.40.50.2300 1 120 4.4E-38 T 06-07-2017 CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 216 3.0E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS24900 b55c62fef80dbcbd1f4de70754d280d1 223 SMART SM00862 145 217 4.5E-15 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS26985 7a631126c70822aed21ec0a691ea473e 438 SUPERFAMILY SSF56176 3 183 3.31E-32 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS26985 7a631126c70822aed21ec0a691ea473e 438 Pfam PF01565 FAD binding domain 42 139 4.1E-13 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS26985 7a631126c70822aed21ec0a691ea473e 438 Gene3D G3DSA:3.30.465.10 69 182 9.5E-21 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS00315 147a1cb1013cec964ffc9d0ea10a2af7 236 SUPERFAMILY SSF52540 3 231 5.87E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00315 147a1cb1013cec964ffc9d0ea10a2af7 236 SMART SM00382 28 216 2.6E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00315 147a1cb1013cec964ffc9d0ea10a2af7 236 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00315 147a1cb1013cec964ffc9d0ea10a2af7 236 Pfam PF00005 ABC transporter 21 163 4.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00315 147a1cb1013cec964ffc9d0ea10a2af7 236 Gene3D G3DSA:3.40.50.300 3 231 3.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09260 047a3546c2acf7977b7a43b07b10cb18 429 TIGRFAM TIGR01933 hflK: HflK protein 96 371 1.9E-88 T 06-07-2017 IPR010201 HflK GO:0016021 CAL12_RS09260 047a3546c2acf7977b7a43b07b10cb18 429 Pfam PF01145 SPFH domain / Band 7 family 97 285 1.7E-27 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS09260 047a3546c2acf7977b7a43b07b10cb18 429 SMART SM00244 94 269 4.6E-25 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS09260 047a3546c2acf7977b7a43b07b10cb18 429 Pfam PF12221 Bacterial membrane protein N terminal 8 55 5.6E-13 T 06-07-2017 IPR020980 Menbrane protein HflK, N-terminal CAL12_RS09260 047a3546c2acf7977b7a43b07b10cb18 429 SUPERFAMILY SSF117892 155 276 2.35E-19 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 SUPERFAMILY SSF52172 1 128 1.01E-25 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 Pfam PF00072 Response regulator receiver domain 4 110 1.8E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 Gene3D G3DSA:3.40.50.2300 1 115 6.1E-27 T 06-07-2017 CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 Pfam PF04397 LytTr DNA-binding domain 145 239 2.1E-8 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 SMART SM00850 143 240 1.2E-7 T 06-07-2017 IPR007492 LytTR DNA-binding domain GO:0003677 CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 Gene3D G3DSA:2.40.50.40 136 204 3.1E-8 T 06-07-2017 CAL12_RS19850 077a883d4a9b704a9d66cbce3be2e68b 250 SMART SM00448 2 110 6.6E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 Gene3D G3DSA:3.30.450.40 94 266 1.2E-51 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 SMART SM00346 23 112 9.8E-26 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 SUPERFAMILY SSF55781 80 265 8.5E-47 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 Gene3D G3DSA:1.10.10.10 23 93 1.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 Pfam PF09339 IclR helix-turn-helix domain 26 75 1.0E-16 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 Pfam PF01614 Bacterial transcriptional regulator 141 261 3.6E-32 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS05735 37165d97cde0e4ed313d66dbd71b6604 286 SUPERFAMILY SSF46785 23 94 1.52E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 SMART SM00893 23 211 1.6E-70 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 Gene3D G3DSA:3.40.50.620 1 247 1.1E-108 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 SUPERFAMILY SSF52402 1 242 5.72E-88 T 06-07-2017 CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 06-07-2017 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105 CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 PIRSF PIRSF000090 1 249 6.6E-88 T 06-07-2017 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105 CAL12_RS18870 87ff68e553b06b1298b4b43a83ba4a4d 249 Pfam PF01012 Electron transfer flavoprotein domain 28 206 8.4E-49 T 06-07-2017 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 15 79 3.0E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 SUPERFAMILY SSF47616 89 208 5.93E-13 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 Pfam PF14834 Glutathione S-transferase, C-terminal domain 97 206 3.8E-40 T 06-07-2017 CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 Gene3D G3DSA:3.40.30.10 4 103 1.9E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 SUPERFAMILY SSF52833 6 92 3.62E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS05025 2a5d097ba9d5cb3b56113f8aec6c06ea 209 Gene3D G3DSA:1.20.1050.10 104 207 9.3E-39 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 PIRSF PIRSF000139 9 411 1.9E-113 T 06-07-2017 IPR012257 Glycolate oxidase, iron-sulphur subunit CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 Gene3D G3DSA:1.10.1060.10 10 107 2.3E-23 T 06-07-2017 CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 SUPERFAMILY SSF46548 20 102 1.26E-20 T 06-07-2017 IPR009051 Alpha-helical ferredoxin GO:0051536 CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 Pfam PF02754 Cysteine-rich domain 305 387 1.2E-11 T 06-07-2017 IPR004017 Cysteine-rich domain CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 Pfam PF02754 Cysteine-rich domain 171 255 6.4E-9 T 06-07-2017 IPR004017 Cysteine-rich domain CAL12_RS17760 63a23db9a8a5059da648fe68da8ad372 419 Pfam PF12838 4Fe-4S dicluster domain 24 89 8.3E-13 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.5E-25 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 Gene3D G3DSA:3.40.190.10 90 177 9.9E-20 T 06-07-2017 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-11 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 SUPERFAMILY SSF46785 1 85 1.32E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 Gene3D G3DSA:3.40.190.10 178 262 4.7E-20 T 06-07-2017 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 SUPERFAMILY SSF53850 89 294 2.02E-39 T 06-07-2017 CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 Pfam PF03466 LysR substrate binding domain 88 290 1.1E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14585 55809d4bf9b436d6d40075e82f221c68 303 Gene3D G3DSA:1.10.10.10 1 85 1.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 Pfam PF00472 RF-1 domain 214 321 5.4E-43 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 Pfam PF03462 PCRF domain 13 203 3.5E-72 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 2.5E-163 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 SMART SM00937 63 178 1.3E-65 T 06-07-2017 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 Gene3D G3DSA:1.20.58.410 7 92 8.6E-19 T 06-07-2017 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.131 T 06-07-2017 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 SUPERFAMILY SSF75620 12 353 9.55E-138 T 06-07-2017 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAL12_RS25885 7e32f7783fc21264bed2ed4018fbe385 360 Gene3D G3DSA:3.30.160.20 213 288 4.4E-36 T 06-07-2017 IPR014720 Double-stranded RNA-binding domain CAL12_RS16515 ad7323194138a247658dfef1d3ae124f 257 Pfam PF00174 Oxidoreductase molybdopterin binding domain 93 234 3.6E-41 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS16515 ad7323194138a247658dfef1d3ae124f 257 Gene3D G3DSA:3.90.420.10 85 254 5.0E-62 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS16515 ad7323194138a247658dfef1d3ae124f 257 SUPERFAMILY SSF56524 40 256 6.8E-56 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS04040 f2e013639675c0e8ec0b2bba74a10ec4 207 SUPERFAMILY SSF52317 1 191 5.81E-37 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS04040 f2e013639675c0e8ec0b2bba74a10ec4 207 Pfam PF01965 DJ-1/PfpI family 3 172 4.4E-18 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS04040 f2e013639675c0e8ec0b2bba74a10ec4 207 Gene3D G3DSA:3.40.50.880 1 196 3.0E-49 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26920 547b0704234d121c2f4a8d10db8b4a8e 349 Gene3D G3DSA:3.40.50.720 49 236 7.0E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26920 547b0704234d121c2f4a8d10db8b4a8e 349 SUPERFAMILY SSF51735 46 344 1.36E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26920 547b0704234d121c2f4a8d10db8b4a8e 349 Gene3D G3DSA:3.90.25.10 237 344 1.1E-26 T 06-07-2017 CAL12_RS26920 547b0704234d121c2f4a8d10db8b4a8e 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 51 279 1.1E-42 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 PIRSF PIRSF000103 1 291 5.2E-65 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 SUPERFAMILY SSF48179 163 288 3.17E-32 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 Gene3D G3DSA:3.40.50.720 1 158 5.1E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 SUPERFAMILY SSF51735 1 158 9.13E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 163 281 1.6E-36 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 157 4.8E-39 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS13585 010ffebe8d738e6f8fae64fc2383932c 295 Gene3D G3DSA:1.10.1040.10 163 289 1.7E-36 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 125 7.6E-20 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 SUPERFAMILY SSF51604 113 379 2.75E-80 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 Gene3D G3DSA:3.30.390.10 2 129 9.7E-46 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 100 125 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 Gene3D G3DSA:3.20.20.120 130 379 5.8E-88 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 SMART SM00922 148 245 9.5E-30 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 SUPERFAMILY SSF54826 3 125 2.0E-32 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS14800 2424928825f70a2e8cd8f5ca38b1e80e 380 Pfam PF13378 Enolase C-terminal domain-like 151 372 1.5E-70 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS16395 946629f23ff976b9836a44e477910332 259 SUPERFAMILY SSF51182 15 182 1.42E-16 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS16395 946629f23ff976b9836a44e477910332 259 SUPERFAMILY SSF46689 211 255 9.68E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16395 946629f23ff976b9836a44e477910332 259 Pfam PF02311 AraC-like ligand binding domain 23 93 3.2E-8 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS16395 946629f23ff976b9836a44e477910332 259 Pfam PF12833 Helix-turn-helix domain 179 255 2.3E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16395 946629f23ff976b9836a44e477910332 259 Gene3D G3DSA:1.10.10.60 214 254 4.1E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16395 946629f23ff976b9836a44e477910332 259 Gene3D G3DSA:1.10.10.60 155 209 7.6E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16395 946629f23ff976b9836a44e477910332 259 Gene3D G3DSA:2.60.120.10 24 90 2.1E-11 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS16395 946629f23ff976b9836a44e477910332 259 SMART SM00342 173 255 2.3E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Gene3D G3DSA:3.40.50.10490 452 573 1.8E-25 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Gene3D G3DSA:3.20.20.70 7 370 7.1E-113 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 TIGRFAM TIGR00876 tal_mycobact: transaldolase 16 367 8.7E-95 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Hamap MF_00493 Transaldolase [tal]. 1 380 127.599 T 06-07-2017 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 ProSitePatterns PS01054 Transaldolase signature 1. 45 53 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 SUPERFAMILY SSF51569 10 373 2.32E-76 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 ProSitePatterns PS00958 Transaldolase active site. 142 159 - T 06-07-2017 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Gene3D G3DSA:3.40.50.10490 574 677 1.6E-27 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Gene3D G3DSA:3.40.50.10490 849 929 3.7E-11 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Pfam PF00342 Phosphoglucose isomerase 458 669 1.5E-15 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Pfam PF00923 Transaldolase 19 368 1.6E-81 T 06-07-2017 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 Gene3D G3DSA:3.40.50.10490 686 778 4.7E-13 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 SUPERFAMILY SSF53697 423 791 2.27E-76 T 06-07-2017 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 PRINTS PR00662 Glucose-6-phosphate isomerase signature 573 591 2.1E-9 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 PRINTS PR00662 Glucose-6-phosphate isomerase signature 461 480 2.1E-9 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS22840 a629adb9bf6dc2f1b05b45bda9597d04 947 PRINTS PR00662 Glucose-6-phosphate isomerase signature 648 669 2.1E-9 T 06-07-2017 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CAL12_RS04850 45ed90d076ef332c1d09d6d38196cada 335 SUPERFAMILY SSF51430 2 309 3.14E-85 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS04850 45ed90d076ef332c1d09d6d38196cada 335 Pfam PF00248 Aldo/keto reductase family 6 310 3.5E-64 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS04850 45ed90d076ef332c1d09d6d38196cada 335 Gene3D G3DSA:3.20.20.100 1 310 1.5E-84 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 SMART SM00936 335 425 7.6E-28 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 335 425 4.9E-19 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 SUPERFAMILY SSF69189 335 427 9.61E-22 T 06-07-2017 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 133 1.5E-18 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 202 215 1.5E-18 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 175 192 1.5E-18 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 Gene3D G3DSA:3.40.710.10 88 335 3.1E-100 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 92 315 2.8E-80 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 Gene3D G3DSA:2.60.410.10 336 424 5.5E-25 T 06-07-2017 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 SUPERFAMILY SSF56601 94 335 4.4E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS26795 6048a06bf7c7f5178fec095dc543e712 441 SUPERFAMILY SSF56601 26 34 4.4E-84 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 SUPERFAMILY SSF53850 23 329 5.44E-73 T 06-07-2017 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 Gene3D G3DSA:3.40.190.10 193 299 7.8E-20 T 06-07-2017 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 Gene3D G3DSA:3.40.190.10 24 169 1.7E-42 T 06-07-2017 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 21 329 3.4E-125 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 147 155 - T 06-07-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 Pfam PF13531 Bacterial extracellular solute-binding protein 37 284 2.4E-35 T 06-07-2017 CAL12_RS01645 5f82165f1802954694f1e42ab022fdc7 334 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 50 62 - T 06-07-2017 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 CAL12_RS11655 c0d891deb589f3ec090d815ecdeb6785 500 SUPERFAMILY SSF103378 37 473 4.45E-112 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS11655 c0d891deb589f3ec090d815ecdeb6785 500 Gene3D G3DSA:3.30.1330.120 301 441 4.7E-28 T 06-07-2017 CAL12_RS11655 c0d891deb589f3ec090d815ecdeb6785 500 Pfam PF03972 MmgE/PrpD family 41 470 2.0E-124 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS00900 4a815661977ac2fd64bd763352c2f866 188 Pfam PF02417 Chromate transporter 12 170 5.7E-27 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS16225 674e0fb32a588d62e40717d8a6cc4165 467 SUPERFAMILY SSF103378 7 461 1.44E-105 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS16225 674e0fb32a588d62e40717d8a6cc4165 467 Gene3D G3DSA:3.30.1330.120 276 418 2.9E-20 T 06-07-2017 CAL12_RS16225 674e0fb32a588d62e40717d8a6cc4165 467 Pfam PF03972 MmgE/PrpD family 11 453 1.2E-111 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS14650 7b8d8b96f04b25977f36f3d428fbff49 470 Pfam PF01425 Amidase 33 263 5.1E-81 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS14650 7b8d8b96f04b25977f36f3d428fbff49 470 Pfam PF01425 Amidase 341 461 6.6E-17 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS14650 7b8d8b96f04b25977f36f3d428fbff49 470 Gene3D G3DSA:3.90.1300.10 14 462 6.6E-127 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS14650 7b8d8b96f04b25977f36f3d428fbff49 470 SUPERFAMILY SSF75304 6 466 7.85E-122 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 Gene3D G3DSA:3.40.47.10 4 169 3.9E-70 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 327 4.9E-32 T 06-07-2017 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 6.7E-34 T 06-07-2017 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 8 327 8.1E-120 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 Gene3D G3DSA:3.40.47.10 170 328 1.0E-48 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 SUPERFAMILY SSF53901 8 328 1.89E-70 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08355 401773e276ee4b253de06600271a2500 330 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 328 68.972 T 06-07-2017 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CAL12_RS00215 9d97bbf72062ffacc7402ca5b3df6e19 194 Pfam PF13663 Domain of unknown function (DUF4148) 88 154 4.7E-9 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS17100 200bfd670eaf525eecf881a54842d9e1 224 SUPERFAMILY SSF52540 6 224 1.05E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17100 200bfd670eaf525eecf881a54842d9e1 224 SMART SM00382 34 222 5.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17100 200bfd670eaf525eecf881a54842d9e1 224 Gene3D G3DSA:3.40.50.300 5 224 6.2E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17100 200bfd670eaf525eecf881a54842d9e1 224 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17100 200bfd670eaf525eecf881a54842d9e1 224 Pfam PF00005 ABC transporter 25 173 9.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 1.1E-7 T 06-07-2017 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 PRINTS PR00419 Adrenodoxin reductase family signature 8 30 1.1E-7 T 06-07-2017 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 Pfam PF01593 Flavin containing amine oxidoreductase 18 405 2.3E-29 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 Gene3D G3DSA:3.50.50.60 7 106 7.0E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 Gene3D G3DSA:3.50.50.60 194 310 7.0E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 SUPERFAMILY SSF51905 396 428 2.5E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26965 d06bc12e01ce85d1bfe118977dc789fe 436 SUPERFAMILY SSF51905 7 297 2.5E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 Gene3D G3DSA:1.20.200.10 105 372 7.2E-83 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00145 Argininosuccinate lyase family signature 142 162 3.4E-11 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00145 Argininosuccinate lyase family signature 101 123 3.4E-11 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00145 Argininosuccinate lyase family signature 277 293 3.4E-11 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 3.4E-11 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 Pfam PF00206 Lyase 17 295 1.2E-51 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00149 Fumarate lyase superfamily signature 102 120 4.1E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 4.1E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00149 Fumarate lyase superfamily signature 147 165 4.1E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 PRINTS PR00149 Fumarate lyase superfamily signature 277 293 4.1E-26 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 ProSitePatterns PS00163 Fumarate lyases signature. 277 286 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 Gene3D G3DSA:1.10.40.30 373 444 1.1E-22 T 06-07-2017 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 Pfam PF10397 Adenylosuccinate lyase C-terminus 366 442 1.4E-15 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 SUPERFAMILY SSF48557 11 446 2.51E-111 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 Gene3D G3DSA:1.10.275.10 5 104 1.4E-33 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 SMART SM00998 365 444 1.8E-22 T 06-07-2017 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS14835 e453a0c87131655a877f1a75188f2f4c 455 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 443 2.4E-109 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Pfam PF01541 GIY-YIG catalytic domain 19 93 9.0E-10 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Pfam PF14520 Helix-hairpin-helix domain 555 606 7.9E-7 T 06-07-2017 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SUPERFAMILY SSF46600 190 242 1.31E-11 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 7 587 4.9E-168 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Gene3D G3DSA:4.10.860.10 182 242 1.7E-16 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 605 27.129 T 06-07-2017 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SUPERFAMILY SSF82771 17 100 3.79E-22 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Gene3D G3DSA:1.10.150.20 554 607 1.2E-20 T 06-07-2017 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Gene3D G3DSA:3.40.1440.10 18 97 1.4E-8 T 06-07-2017 IPR027299 GIY-YIG domain CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SUPERFAMILY SSF47781 522 607 3.81E-19 T 06-07-2017 IPR010994 RuvA domain 2-like CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Pfam PF02151 UvrB/uvrC motif 203 235 4.5E-6 T 06-07-2017 IPR001943 UVR domain GO:0005515 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 394 540 1.6E-46 T 06-07-2017 IPR001162 UvrC family homology region CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SMART SM00465 17 98 9.1E-18 T 06-07-2017 IPR000305 GIY-YIG nuclease superfamily CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SMART SM00278 554 573 15.0 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS08885 87d06d943a0c743465651eedaa328411 607 SMART SM00278 586 605 0.43 T 06-07-2017 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 SUPERFAMILY SSF46689 206 255 3.23E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 Gene3D G3DSA:1.10.10.60 202 258 3.2E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 Gene3D G3DSA:1.10.10.60 259 307 2.1E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 SUPERFAMILY SSF46689 258 307 2.28E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 SUPERFAMILY SSF51182 41 102 9.54E-8 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 Pfam PF12833 Helix-turn-helix domain 228 306 1.1E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 Pfam PF12852 Cupin 7 191 1.5E-48 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 SMART SM00342 222 305 9.1E-28 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 289 305 1.9E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 289 1.9E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS13870 f1a5d3fc4d6410a2078f481902b33dab 309 Gene3D G3DSA:2.60.120.10 41 99 1.1E-5 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS10915 fa3bf8d8275c34597283ba4761b7350f 150 Gene3D G3DSA:3.40.140.10 1 142 1.0E-56 T 06-07-2017 CAL12_RS10915 fa3bf8d8275c34597283ba4761b7350f 150 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 2 144 47.513 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAL12_RS10915 fa3bf8d8275c34597283ba4761b7350f 150 SUPERFAMILY SSF53927 1 145 4.94E-53 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS10915 fa3bf8d8275c34597283ba4761b7350f 150 Pfam PF14437 MafB19-like deaminase 2 144 7.3E-31 T 06-07-2017 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CAL12_RS10915 fa3bf8d8275c34597283ba4761b7350f 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 48 85 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 SUPERFAMILY SSF53850 90 297 6.81E-43 T 06-07-2017 CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 SUPERFAMILY SSF46785 1 111 3.74E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 Gene3D G3DSA:3.40.190.10 91 177 1.8E-17 T 06-07-2017 CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 Gene3D G3DSA:3.40.190.10 178 264 1.7E-20 T 06-07-2017 CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 Gene3D G3DSA:1.10.10.10 3 86 6.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18505 96e3d770e71fca6abbc37aca8580a5c9 300 Pfam PF03466 LysR substrate binding domain 89 294 1.5E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 SUPERFAMILY SSF52540 3 242 4.37E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 SUPERFAMILY SSF50331 279 366 7.37E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 Pfam PF00005 ABC transporter 19 161 5.9E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 SMART SM00382 28 211 1.0E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 Gene3D G3DSA:3.40.50.300 2 234 5.4E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 365 7.6E-108 T 06-07-2017 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CAL12_RS02365 957af8f766fbc48692f780cc613a42dc 366 Pfam PF08402 TOBE domain 286 365 2.6E-12 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS05365 338cddc95594c3be802ef1e07e442308 252 Gene3D G3DSA:1.10.3720.10 23 236 2.5E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05365 338cddc95594c3be802ef1e07e442308 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 237 1.2E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05365 338cddc95594c3be802ef1e07e442308 252 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 22 131 2.8E-18 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS05365 338cddc95594c3be802ef1e07e442308 252 SUPERFAMILY SSF161098 24 222 6.67E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18775 c0d6ce5d79bcfd149f4605d6c6cfd393 286 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 26 283 1.4E-77 T 06-07-2017 IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal GO:0016874 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS18775 c0d6ce5d79bcfd149f4605d6c6cfd393 286 Gene3D G3DSA:3.90.226.10 91 220 1.1E-13 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18775 c0d6ce5d79bcfd149f4605d6c6cfd393 286 SUPERFAMILY SSF52096 43 227 3.91E-15 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18775 c0d6ce5d79bcfd149f4605d6c6cfd393 286 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 22 283 4.0E-90 T 06-07-2017 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 Pfam PF01494 FAD binding domain 36 325 1.5E-25 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 Gene3D G3DSA:3.50.50.60 290 327 6.8E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 Gene3D G3DSA:3.50.50.60 36 192 6.8E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 1.1E-15 T 06-07-2017 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 1.1E-15 T 06-07-2017 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 1.1E-15 T 06-07-2017 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 1.1E-15 T 06-07-2017 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 SUPERFAMILY SSF51905 279 386 4.88E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14745 f2d3e4c10aa7dcdd07d5c1158cf7579e 414 SUPERFAMILY SSF51905 36 189 4.88E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12835 b3d406fba65f9cb4bcecd2e1e51ab8ad 207 Pfam PF00857 Isochorismatase family 24 199 7.7E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS12835 b3d406fba65f9cb4bcecd2e1e51ab8ad 207 SUPERFAMILY SSF52499 20 204 5.89E-52 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS12835 b3d406fba65f9cb4bcecd2e1e51ab8ad 207 Gene3D G3DSA:3.40.50.850 25 205 4.1E-51 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 467 2.1E-156 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 Gene3D G3DSA:3.40.50.2020 274 446 1.2E-44 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 Pfam PF13522 Glutamine amidotransferase domain 64 211 4.8E-16 T 06-07-2017 CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 Gene3D G3DSA:3.60.20.10 2 261 5.4E-58 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 469 44.817 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 Pfam PF00156 Phosphoribosyl transferase domain 287 395 2.8E-8 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 SUPERFAMILY SSF53271 253 484 6.42E-71 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 SUPERFAMILY SSF56235 2 260 1.37E-68 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS12090 33ae5e4c94933ee91dfda813e3904f07 506 PIRSF PIRSF000485 1 483 1.6E-155 T 06-07-2017 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 221 1.0E-44 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 Pfam PF01300 Telomere recombination 21 210 1.1E-45 T 06-07-2017 IPR006070 YrdC-like domain GO:0003725 CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 Pfam PF03481 Putative GTP-binding controlling metal-binding 212 342 3.2E-19 T 06-07-2017 IPR005145 Putative GTP-binding controlling metal-binding domain CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 SUPERFAMILY SSF55821 13 221 1.62E-50 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 Gene3D G3DSA:3.90.870.10 7 217 3.6E-68 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS05235 eaf4e1ae623b93ed7f06461fd9b63e23 345 PIRSF PIRSF004930 2 345 8.5E-92 T 06-07-2017 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CAL12_RS16700 f6c1775bceb547fd4a023609838145c8 321 Gene3D G3DSA:3.90.25.10 206 315 2.1E-4 T 06-07-2017 CAL12_RS16700 f6c1775bceb547fd4a023609838145c8 321 SUPERFAMILY SSF51735 4 315 6.6E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16700 f6c1775bceb547fd4a023609838145c8 321 Pfam PF13460 NAD(P)H-binding 11 161 4.7E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16700 f6c1775bceb547fd4a023609838145c8 321 Gene3D G3DSA:3.40.50.720 3 205 2.2E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06590 d57a4e7c0f234bf330f19041ae25ab70 285 SUPERFAMILY SSF161098 31 278 2.62E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06590 d57a4e7c0f234bf330f19041ae25ab70 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 279 8.9E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06590 d57a4e7c0f234bf330f19041ae25ab70 285 Gene3D G3DSA:1.10.3720.10 69 284 5.6E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06590 d57a4e7c0f234bf330f19041ae25ab70 285 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 20 283 2.1E-81 T 06-07-2017 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 Gene3D G3DSA:3.50.50.60 125 187 1.4E-4 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 Pfam PF04324 BFD-like [2Fe-2S] binding domain 385 436 4.0E-8 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 7.6E-14 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 7.6E-14 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.6E-14 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 SUPERFAMILY SSF51905 1 340 6.72E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.1E-11 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 1.1E-11 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 120 129 1.1E-11 T 06-07-2017 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 PIRSF PIRSF037495 1 475 5.4E-162 T 06-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 Gene3D G3DSA:3.50.50.60 269 339 4.5E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 Gene3D G3DSA:3.50.50.60 4 124 4.5E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07110 c9f240d40a03f3b1648f039ae6c1d604 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 325 1.5E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27385 dbfe1e6bbb2031dab55f20e32890f622 390 Gene3D G3DSA:3.40.50.300 203 359 2.1E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27385 dbfe1e6bbb2031dab55f20e32890f622 390 SUPERFAMILY SSF52540 202 362 3.51E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18530 71777d39c3058401781187ed552cfb8f 443 Gene3D G3DSA:3.90.1300.10 6 441 3.7E-119 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS18530 71777d39c3058401781187ed552cfb8f 443 Pfam PF01425 Amidase 24 431 1.0E-85 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS18530 71777d39c3058401781187ed552cfb8f 443 SUPERFAMILY SSF75304 6 441 1.18E-114 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS18840 4bb0fd3a4b3737e4d727aadedf590395 759 SUPERFAMILY SSF117074 52 108 5.49E-5 T 06-07-2017 CAL12_RS18840 4bb0fd3a4b3737e4d727aadedf590395 759 Pfam PF04185 Phosphoesterase family 320 678 4.7E-9 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.9E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 Gene3D G3DSA:3.40.50.720 1 265 7.1E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 201 1.1E-5 T 06-07-2017 CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 SUPERFAMILY SSF51735 2 258 5.55E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.1E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01410 e04f8b5293c149c5081e332a8b2f63ee 305 Pfam PF00106 short chain dehydrogenase 8 195 1.2E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04525 b83ba012c4fe2d7f28fe1cb71bb0d63e 477 SUPERFAMILY SSF89796 31 211 7.98E-25 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS04525 b83ba012c4fe2d7f28fe1cb71bb0d63e 477 Pfam PF02515 CoA-transferase family III 216 408 5.1E-43 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS04525 b83ba012c4fe2d7f28fe1cb71bb0d63e 477 Gene3D G3DSA:3.40.50.10540 212 472 3.8E-59 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS04525 b83ba012c4fe2d7f28fe1cb71bb0d63e 477 SUPERFAMILY SSF89796 214 412 4.84E-51 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS04525 b83ba012c4fe2d7f28fe1cb71bb0d63e 477 Gene3D G3DSA:3.40.50.10540 27 189 2.9E-8 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS12380 5371b63c5480888763ca02e9484d2a19 226 Gene3D G3DSA:2.60.120.590 28 225 1.0E-54 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAL12_RS12380 5371b63c5480888763ca02e9484d2a19 226 SUPERFAMILY SSF51197 28 224 2.75E-59 T 06-07-2017 CAL12_RS12380 5371b63c5480888763ca02e9484d2a19 226 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 43 223 1.1E-54 T 06-07-2017 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 TIGRFAM TIGR02544 III_secr_YscJ: type III secretion apparatus lipoprotein, YscJ/HrcJ family 12 197 1.6E-67 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 82 95 7.1E-25 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 102 117 7.1E-25 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 170 182 7.1E-25 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 122 135 7.1E-25 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 PRINTS PR01338 Type III secretion system outer membrane K protein family signature 31 41 7.1E-25 T 06-07-2017 IPR003282 Type III secretion system lipoprotein HrcJ/YscJ GO:0009306 CAL12_RS22090 cadaa4e1dd4e0f4053b6bbcdbdda7d7c 288 Pfam PF01514 Secretory protein of YscJ/FliF family 10 191 1.3E-30 T 06-07-2017 IPR006182 Secretory protein YscJ/FliF CAL12_RS04310 699f958f8a54aa683aa452fa226fa2fc 552 Pfam PF13538 UvrD-like helicase C-terminal domain 483 530 4.3E-9 T 06-07-2017 IPR027785 UvrD-like helicase C-terminal domain CAL12_RS04310 699f958f8a54aa683aa452fa226fa2fc 552 SUPERFAMILY SSF52540 221 534 1.72E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04310 699f958f8a54aa683aa452fa226fa2fc 552 Gene3D G3DSA:3.40.50.300 378 540 1.2E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04310 699f958f8a54aa683aa452fa226fa2fc 552 Gene3D G3DSA:3.40.50.300 219 377 1.9E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14400 c80d9accbdaaf13854b88734b1f37261 396 SUPERFAMILY SSF111369 62 306 4.45E-55 T 06-07-2017 CAL12_RS14400 c80d9accbdaaf13854b88734b1f37261 396 Gene3D G3DSA:2.40.50.100 71 104 4.5E-17 T 06-07-2017 CAL12_RS14400 c80d9accbdaaf13854b88734b1f37261 396 Gene3D G3DSA:2.40.50.100 179 204 4.5E-17 T 06-07-2017 CAL12_RS14400 c80d9accbdaaf13854b88734b1f37261 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 381 9.7E-74 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS14400 c80d9accbdaaf13854b88734b1f37261 396 Pfam PF13533 Biotin-lipoyl like 73 118 8.5E-12 T 06-07-2017 CAL12_RS05880 d07e496b748c6a8fccee9495cf9853f1 283 Gene3D G3DSA:1.10.3720.10 80 276 6.3E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05880 d07e496b748c6a8fccee9495cf9853f1 283 SUPERFAMILY SSF161098 83 266 1.11E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05880 d07e496b748c6a8fccee9495cf9853f1 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 271 7.8E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 Pfam PF04216 Protein involved in formate dehydrogenase formation 17 310 2.8E-110 T 06-07-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 Gene3D G3DSA:3.90.1670.10 21 313 6.7E-91 T 06-07-2017 IPR024064 FdhE-like CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 SUPERFAMILY SSF144020 21 311 2.22E-83 T 06-07-2017 IPR024064 FdhE-like CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 Hamap MF_00611 Protein FdhE [fdhE]. 2 312 34.206 T 06-07-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 PIRSF PIRSF018296 1 314 4.3E-100 T 06-07-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CAL12_RS19445 5250043dee993fe1e6b1be9dae44b7a3 314 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 309 2.8E-85 T 06-07-2017 IPR006452 Formate dehydrogenase accessory protein GO:0005737 CAL12_RS26625 c77a35501d9d64690fe0fb871faf1445 373 Pfam PF13692 Glycosyl transferases group 1 210 322 1.6E-20 T 06-07-2017 CAL12_RS26625 c77a35501d9d64690fe0fb871faf1445 373 Pfam PF13439 Glycosyltransferase Family 4 14 166 9.7E-20 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS26625 c77a35501d9d64690fe0fb871faf1445 373 SUPERFAMILY SSF53756 1 357 2.55E-65 T 06-07-2017 CAL12_RS26625 c77a35501d9d64690fe0fb871faf1445 373 Gene3D G3DSA:3.40.50.2000 156 339 1.7E-22 T 06-07-2017 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.7E-81 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 Gene3D G3DSA:3.40.50.720 138 263 1.0E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 280 3.9E-69 T 06-07-2017 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 Gene3D G3DSA:3.40.192.10 7 137 1.7E-49 T 06-07-2017 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 SUPERFAMILY SSF53223 1 121 2.21E-40 T 06-07-2017 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 06-07-2017 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 6.2E-40 T 06-07-2017 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.548 T 06-07-2017 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CAL12_RS11725 e4d3580a53c0fcd9943597635c84d7a0 282 SUPERFAMILY SSF51735 122 279 8.42E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 71 281 34.536 T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 77 276 3.2E-55 T 06-07-2017 CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 Gene3D G3DSA:3.40.50.150 83 278 2.4E-58 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 SUPERFAMILY SSF53335 74 278 2.59E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 72 278 5.6E-57 T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAL12_RS15980 066dfc7976db33adebf0635020e8dbfd 281 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 202 217 - T 06-07-2017 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 19 363 6.9E-130 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 SUPERFAMILY SSF52518 366 554 5.04E-67 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Pfam PF02780 Transketolase, C-terminal domain 577 684 2.1E-11 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Pfam PF02779 Transketolase, pyrimidine binding domain 379 551 5.0E-40 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 SUPERFAMILY SSF52922 562 695 5.63E-41 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 TIGRFAM TIGR00232 tktlase_bact: transketolase 21 690 3.8E-253 T 06-07-2017 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Gene3D G3DSA:3.40.50.920 566 694 8.1E-50 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Gene3D G3DSA:3.40.50.970 359 558 2.9E-74 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 SMART SM00861 380 552 5.4E-66 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 Gene3D G3DSA:3.40.50.970 8 346 1.8E-117 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 SUPERFAMILY SSF52518 11 345 6.91E-103 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS22835 5fba3154943047e393c84bae752b34db 699 ProSitePatterns PS00802 Transketolase signature 2. 494 510 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 8.3E-69 T 06-07-2017 CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 221 2.9E-4 T 06-07-2017 CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 8.2E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 SUPERFAMILY SSF51735 5 249 1.22E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 9.8E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03485 bab8c7960ca0df476a84affaffcb61ae 251 Gene3D G3DSA:3.40.50.720 3 249 3.5E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02075 94dcb60638262fba975a5cdb12f25bd0 377 Gene3D G3DSA:3.90.1150.10 227 359 4.2E-15 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS02075 94dcb60638262fba975a5cdb12f25bd0 377 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 212 225 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAL12_RS02075 94dcb60638262fba975a5cdb12f25bd0 377 Pfam PF00155 Aminotransferase class I and II 20 358 2.5E-38 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS02075 94dcb60638262fba975a5cdb12f25bd0 377 Gene3D G3DSA:3.40.640.10 33 226 1.7E-43 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02075 94dcb60638262fba975a5cdb12f25bd0 377 SUPERFAMILY SSF53383 8 366 1.03E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 Gene3D G3DSA:1.10.10.10 1 85 3.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 Pfam PF03466 LysR substrate binding domain 85 258 1.5E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 SUPERFAMILY SSF46785 2 109 3.81E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 SUPERFAMILY SSF53850 87 295 2.04E-28 T 06-07-2017 CAL12_RS15195 15ee19c90656f6b9d4fdd9f0324058a2 296 Gene3D G3DSA:3.40.190.10 86 219 4.2E-27 T 06-07-2017 CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.4E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 Gene3D G3DSA:3.40.190.10 174 259 4.7E-21 T 06-07-2017 CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 Gene3D G3DSA:3.40.190.10 83 173 2.8E-12 T 06-07-2017 CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 SUPERFAMILY SSF53850 90 296 3.1E-47 T 06-07-2017 CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 Gene3D G3DSA:1.10.10.10 4 82 7.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 SUPERFAMILY SSF46785 4 85 5.32E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05460 00c34c81b37f6331cb16a829590d48e4 300 Pfam PF03466 LysR substrate binding domain 89 292 2.0E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 SUPERFAMILY SSF46894 3 97 3.4E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 Gene3D G3DSA:1.10.10.10 3 99 1.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 SMART SM00862 21 96 6.0E-16 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 96 4.1E-17 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 Gene3D G3DSA:1.25.40.10 275 488 2.2E-20 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS13010 505e2bceea2331a200813859f3004bed 527 SUPERFAMILY SSF48452 276 492 1.9E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS23315 d1d9bad18464b2c594a1971b1e5d484f 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 3.2E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23315 d1d9bad18464b2c594a1971b1e5d484f 277 SUPERFAMILY SSF161098 69 258 4.32E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23315 d1d9bad18464b2c594a1971b1e5d484f 277 Gene3D G3DSA:1.10.3720.10 65 271 1.5E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01230 e80dbd332d7796e0ef879aaa0fcdc320 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 6.9E-26 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS01230 e80dbd332d7796e0ef879aaa0fcdc320 224 Gene3D G3DSA:1.10.3720.10 14 217 1.9E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01230 e80dbd332d7796e0ef879aaa0fcdc320 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 217 1.0E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01230 e80dbd332d7796e0ef879aaa0fcdc320 224 SUPERFAMILY SSF161098 15 208 3.27E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 Gene3D G3DSA:1.10.10.10 27 102 1.5E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 101 2.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 Pfam PF07729 FCD domain 111 233 2.1E-26 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 Gene3D G3DSA:1.20.120.530 105 241 7.4E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 SUPERFAMILY SSF48008 108 237 2.07E-24 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 SMART SM00345 43 101 2.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 SMART SM00895 111 234 7.1E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS01860 654c47f583672f216b47f2683042ace7 264 SUPERFAMILY SSF46785 36 105 1.4E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 Gene3D G3DSA:3.40.190.10 14 161 1.6E-43 T 06-07-2017 CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 SUPERFAMILY SSF53850 14 223 1.28E-64 T 06-07-2017 CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 162 183 - T 06-07-2017 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 Pfam PF01634 ATP phosphoribosyltransferase 64 220 8.9E-48 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 14 227 54.605 T 06-07-2017 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CAL12_RS00845 bcf7dbe1e4b4ea62ac7ad241afc64897 237 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 15 203 6.5E-59 T 06-07-2017 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CAL12_RS23755 8bb3a09edd87c9f16ea1c88c1dfe758d 389 Gene3D G3DSA:1.10.287.950 92 299 1.4E-29 T 06-07-2017 CAL12_RS23755 8bb3a09edd87c9f16ea1c88c1dfe758d 389 SUPERFAMILY SSF58104 67 330 1.31E-32 T 06-07-2017 CAL12_RS23755 8bb3a09edd87c9f16ea1c88c1dfe758d 389 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 135 305 2.2E-22 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS23755 8bb3a09edd87c9f16ea1c88c1dfe758d 389 SMART SM00283 84 351 6.9E-5 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS09480 498d82914ff54c829a6b05f672977e87 155 Gene3D G3DSA:1.10.10.10 12 58 3.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09480 498d82914ff54c829a6b05f672977e87 155 Pfam PF02631 RecX family 41 150 1.2E-25 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAL12_RS09480 498d82914ff54c829a6b05f672977e87 155 Gene3D G3DSA:1.10.10.10 61 94 1.8E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09480 498d82914ff54c829a6b05f672977e87 155 Hamap MF_01114 Regulatory protein RecX [recX]. 2 155 13.159 T 06-07-2017 IPR003783 Regulatory protein RecX GO:0006282 CAL12_RS09480 498d82914ff54c829a6b05f672977e87 155 Gene3D G3DSA:1.10.10.10 106 153 1.3E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12590 83f1738f4e1da1ac267fde29786c061f 472 Pfam PF03972 MmgE/PrpD family 13 454 1.6E-111 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS12590 83f1738f4e1da1ac267fde29786c061f 472 Gene3D G3DSA:3.30.1330.120 279 419 6.4E-19 T 06-07-2017 CAL12_RS12590 83f1738f4e1da1ac267fde29786c061f 472 SUPERFAMILY SSF103378 10 460 6.8E-109 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS22830 0d8353e758ee4c7683d6f36c9b901d95 236 SUPERFAMILY SSF53067 5 232 7.07E-27 T 06-07-2017 CAL12_RS22830 0d8353e758ee4c7683d6f36c9b901d95 236 Pfam PF00480 ROK family 6 143 3.7E-17 T 06-07-2017 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CAL12_RS22830 0d8353e758ee4c7683d6f36c9b901d95 236 Gene3D G3DSA:3.30.420.40 123 231 2.2E-11 T 06-07-2017 CAL12_RS22830 0d8353e758ee4c7683d6f36c9b901d95 236 Gene3D G3DSA:3.30.420.40 5 107 1.5E-30 T 06-07-2017 CAL12_RS12365 da055055e471f19a07d48726869200a0 386 Gene3D G3DSA:3.60.21.10 157 337 2.2E-25 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS12365 da055055e471f19a07d48726869200a0 386 SUPERFAMILY SSF56300 157 381 1.49E-39 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS12365 da055055e471f19a07d48726869200a0 386 Pfam PF00149 Calcineurin-like phosphoesterase 157 325 8.3E-9 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS22860 f2dd84cd3fdfea9cddf0f784cd9d7a20 238 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 12 229 4.0E-69 T 06-07-2017 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CAL12_RS22860 f2dd84cd3fdfea9cddf0f784cd9d7a20 238 SUPERFAMILY SSF100950 7 237 1.38E-65 T 06-07-2017 CAL12_RS22860 f2dd84cd3fdfea9cddf0f784cd9d7a20 238 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 236 1.3E-63 T 06-07-2017 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CAL12_RS22860 f2dd84cd3fdfea9cddf0f784cd9d7a20 238 Gene3D G3DSA:3.40.50.1360 7 236 2.7E-75 T 06-07-2017 CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 SUPERFAMILY SSF103473 491 516 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 SUPERFAMILY SSF103473 267 438 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 SUPERFAMILY SSF103473 17 212 3.01E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 Pfam PF07690 Major Facilitator Superfamily 35 428 4.8E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 30 512 1.2E-152 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 Gene3D G3DSA:1.20.1250.20 492 518 1.5E-20 T 06-07-2017 CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 Gene3D G3DSA:1.20.1250.20 284 439 1.5E-20 T 06-07-2017 CAL12_RS19840 960fdbe3c3bfdce4a65fc8226207d3b0 529 Gene3D G3DSA:1.20.1250.20 32 215 5.1E-32 T 06-07-2017 CAL12_RS13995 22b95895ef844632d4ae642a5d684815 582 Pfam PF02538 Hydantoinase B/oxoprolinase 14 539 5.9E-158 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS21080 b773cfbb6cdaf9938dbf29bf63a22f20 164 Gene3D G3DSA:3.40.630.30 1 163 5.8E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS21080 b773cfbb6cdaf9938dbf29bf63a22f20 164 Pfam PF00583 Acetyltransferase (GNAT) family 59 138 3.5E-16 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS21080 b773cfbb6cdaf9938dbf29bf63a22f20 164 SUPERFAMILY SSF55729 1 163 1.51E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS09390 20b438647ef5e4e8cabb4cd68b838ee7 541 PIRSF PIRSF038984 1 536 1.1E-239 T 06-07-2017 IPR028348 FAD dependent protein CAL12_RS09390 20b438647ef5e4e8cabb4cd68b838ee7 541 Gene3D G3DSA:3.50.50.60 473 531 1.1E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09390 20b438647ef5e4e8cabb4cd68b838ee7 541 Gene3D G3DSA:3.50.50.60 101 289 1.1E-30 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09390 20b438647ef5e4e8cabb4cd68b838ee7 541 SUPERFAMILY SSF51905 479 531 3.64E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09390 20b438647ef5e4e8cabb4cd68b838ee7 541 SUPERFAMILY SSF51905 101 287 3.64E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 SUPERFAMILY SSF53850 92 298 4.87E-38 T 06-07-2017 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.7E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 Gene3D G3DSA:3.40.190.10 184 260 5.0E-21 T 06-07-2017 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.5E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 Gene3D G3DSA:3.40.190.10 91 183 1.5E-21 T 06-07-2017 CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 Gene3D G3DSA:1.10.10.10 1 82 1.4E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 SUPERFAMILY SSF46785 3 113 1.52E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13630 5e195e60e5a27a0ae7e4c1877dd62e35 310 Pfam PF03466 LysR substrate binding domain 89 291 1.3E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 Pfam PF07715 TonB-dependent Receptor Plug Domain 96 200 6.6E-22 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 SUPERFAMILY SSF56935 52 733 1.1E-143 T 06-07-2017 CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 Pfam PF00593 TonB dependent receptor 500 732 8.0E-31 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 Gene3D G3DSA:2.40.170.20 214 733 1.1E-153 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 98 731 7.8E-125 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS11070 437d793a328aadfc8883535be6112c38 733 Gene3D G3DSA:2.170.130.10 75 207 2.5E-38 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 Gene3D G3DSA:3.40.190.10 102 189 8.9E-5 T 06-07-2017 CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 Gene3D G3DSA:1.10.10.10 17 99 2.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 Pfam PF03466 LysR substrate binding domain 101 307 1.2E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 SUPERFAMILY SSF53850 103 307 7.42E-36 T 06-07-2017 CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 76 1.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 Gene3D G3DSA:3.40.190.10 190 276 4.9E-21 T 06-07-2017 CAL12_RS14305 086f2e952c70672cdde15ca5af4a6ff6 311 SUPERFAMILY SSF46785 17 101 6.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 PIRSF PIRSF002741 21 531 1.6E-105 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 442 7.1E-95 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 Gene3D G3DSA:3.10.105.10 309 502 7.0E-50 T 06-07-2017 CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 SUPERFAMILY SSF53850 31 515 1.07E-129 T 06-07-2017 CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 Gene3D G3DSA:3.90.76.10 38 194 3.9E-40 T 06-07-2017 CAL12_RS27900 726ca01ea1eca112d9624257fa2264ae 533 Gene3D G3DSA:3.40.190.10 195 308 3.3E-41 T 06-07-2017 CAL12_RS19940 3b7ec15056ae7f4c581cd6c0b87376bc 199 Gene3D G3DSA:3.40.50.300 14 195 1.8E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19940 3b7ec15056ae7f4c581cd6c0b87376bc 199 Pfam PF00005 ABC transporter 14 146 2.1E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS19940 3b7ec15056ae7f4c581cd6c0b87376bc 199 SMART SM00382 23 194 1.7E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19940 3b7ec15056ae7f4c581cd6c0b87376bc 199 SUPERFAMILY SSF52540 14 195 2.42E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16390 d1b91c4dbd92e5c36e38de78fefd7893 395 Pfam PF07690 Major Facilitator Superfamily 20 349 2.1E-19 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16390 d1b91c4dbd92e5c36e38de78fefd7893 395 Gene3D G3DSA:1.20.1250.20 18 188 6.5E-8 T 06-07-2017 CAL12_RS16390 d1b91c4dbd92e5c36e38de78fefd7893 395 SUPERFAMILY SSF103473 9 388 2.62E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16390 d1b91c4dbd92e5c36e38de78fefd7893 395 Gene3D G3DSA:1.20.1250.20 206 382 4.3E-15 T 06-07-2017 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 SUPERFAMILY SSF46785 36 140 6.37E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 Pfam PF12802 MarR family 35 88 2.6E-12 T 06-07-2017 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 SMART SM00347 26 124 1.5E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 97 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 Gene3D G3DSA:1.10.10.10 35 135 1.8E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 4.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 4.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 4.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17020 6e548129943cae38ba76300780d53ce2 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 4.8E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16475 a3b0b53d2176cd5503c759efc7bbc7cc 257 SUPERFAMILY SSF53474 8 252 1.12E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16475 a3b0b53d2176cd5503c759efc7bbc7cc 257 Gene3D G3DSA:3.40.50.1820 6 252 2.2E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16475 a3b0b53d2176cd5503c759efc7bbc7cc 257 Pfam PF00561 alpha/beta hydrolase fold 9 239 1.3E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 5.0E-31 T 06-07-2017 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 5.2E-15 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SMART SM00382 170 337 2.4E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SUPERFAMILY SSF52540 90 371 1.63E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 7.8E-210 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Gene3D G3DSA:2.40.50.140 49 117 4.5E-34 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 242.412 T 06-07-2017 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SMART SM00357 52 118 1.1E-17 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SUPERFAMILY SSF68912 1 46 1.49E-11 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Gene3D G3DSA:3.40.50.300 130 417 1.1E-102 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SMART SM00959 5 47 4.2E-16 T 06-07-2017 IPR011112 Rho termination factor, N-terminal GO:0006353 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 SUPERFAMILY SSF50249 49 125 1.16E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Gene3D G3DSA:1.10.720.10 1 47 3.6E-20 T 06-07-2017 CAL12_RS09065 da8771157a52bd7fd56005be99aa6731 418 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 2.1E-23 T 06-07-2017 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 2.7E-11 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 2.7E-11 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 2.7E-11 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 2.7E-11 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 4.5E-15 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 4.5E-15 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 4.5E-15 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 4.5E-15 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 684 700 - T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Gene3D G3DSA:3.50.50.60 115 240 3.0E-34 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Gene3D G3DSA:3.50.50.60 241 317 3.4E-15 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 13 806 0.0 T 06-07-2017 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Gene3D G3DSA:3.30.413.10 637 773 5.4E-33 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 SUPERFAMILY SSF55124 520 646 2.13E-26 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 565 627 2.6E-12 T 06-07-2017 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 SUPERFAMILY SSF51905 9 195 3.74E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00397 Sirohaem Fe-binding site signature 641 659 9.1E-7 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PRINTS PR00397 Sirohaem Fe-binding site signature 684 702 9.1E-7 T 06-07-2017 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Gene3D G3DSA:3.50.50.60 11 114 5.4E-25 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 SUPERFAMILY SSF56014 638 813 9.95E-50 T 06-07-2017 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 PIRSF PIRSF037149 5 840 0.0 T 06-07-2017 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 291 3.4E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 475 6.9E-9 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 SUPERFAMILY SSF51905 155 313 1.2E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06765 213e88eece1f6ff0920a9c57052f1ecf 850 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 637 757 4.2E-18 T 06-07-2017 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 2.0E-82 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 Gene3D G3DSA:3.40.50.1980 30 243 5.1E-79 T 06-07-2017 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 SUPERFAMILY SSF53720 30 431 4.51E-86 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 Pfam PF00815 Histidinol dehydrogenase 27 431 4.6E-167 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 06-07-2017 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 PIRSF PIRSF000099 4 434 7.6E-158 T 06-07-2017 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 431 40.49 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS00840 b9ae9573cd6f94ae26a109f7e5bc9c5f 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 37 430 1.9E-159 T 06-07-2017 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CAL12_RS23540 4e63ad4256917bb91f57f6e82d3a2d3b 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 129 318 1.1E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23540 4e63ad4256917bb91f57f6e82d3a2d3b 335 Gene3D G3DSA:1.10.3720.10 58 332 1.0E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23540 4e63ad4256917bb91f57f6e82d3a2d3b 335 SUPERFAMILY SSF161098 54 327 2.75E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 SUPERFAMILY SSF48498 98 230 1.51E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 1.6E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 4.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 SUPERFAMILY SSF46689 23 85 3.18E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS24280 4e1d8af2f9dc41f79e475fee3146d999 239 Gene3D G3DSA:1.10.357.10 23 189 2.5E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS17010 dff753b37323c44e70a2ea6ddd034028 122 SUPERFAMILY SSF54593 2 120 1.79E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS17010 dff753b37323c44e70a2ea6ddd034028 122 Gene3D G3DSA:3.10.180.10 1 118 4.4E-28 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS16605 79896159eb2e870d9ad9e513b1d48441 327 PIRSF PIRSF017082 1 326 2.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16605 79896159eb2e870d9ad9e513b1d48441 327 SUPERFAMILY SSF53850 115 291 2.58E-14 T 06-07-2017 CAL12_RS16605 79896159eb2e870d9ad9e513b1d48441 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 1.2E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 Pfam PF00005 ABC transporter 367 510 2.9E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 Pfam PF00005 ABC transporter 29 172 1.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 Gene3D G3DSA:3.40.50.300 7 234 3.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 Gene3D G3DSA:3.40.50.300 343 574 3.4E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 SUPERFAMILY SSF52540 9 234 2.61E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 SMART SM00382 38 222 1.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 SMART SM00382 375 556 1.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02905 640b1ba488a1cc225371b3edeaa75db2 602 SUPERFAMILY SSF52540 343 572 5.65E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF00512 His Kinase A (phospho-acceptor) domain 411 476 2.3E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF55874 469 643 2.88E-38 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00388 410 478 9.2E-11 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF55785 27 137 7.68E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:3.30.565.10 478 640 2.5E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF47384 399 475 4.12E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF00072 Response regulator receiver domain 669 779 2.4E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:3.30.450.20 276 386 1.9E-18 T 06-07-2017 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:3.30.450.20 134 254 6.4E-27 T 06-07-2017 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 285 395 1.5E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 255 1.9E-13 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 137 1.6E-15 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF55785 288 388 3.21E-18 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF00989 PAS fold 17 127 6.0E-9 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF00989 PAS fold 283 373 6.6E-9 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00091 280 346 2.2E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00091 14 81 0.0011 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00091 143 209 3.0E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00086 352 388 25.0 T 06-07-2017 IPR001610 PAC motif CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00086 88 131 0.19 T 06-07-2017 IPR001610 PAC motif CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00086 215 257 0.059 T 06-07-2017 IPR001610 PAC motif CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 640 3.4E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00387 519 642 1.5E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF52172 667 784 3.27E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:3.30.450.20 10 127 1.6E-16 T 06-07-2017 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SUPERFAMILY SSF55785 129 254 7.33E-24 T 06-07-2017 IPR000014 PAS domain CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:1.10.287.130 403 474 2.6E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Gene3D G3DSA:3.40.50.2300 667 783 1.7E-28 T 06-07-2017 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 599 5.2E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 585 5.2E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 639 5.2E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 PRINTS PR00344 Bacterial sensor protein C-terminal signature 602 620 5.2E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 Pfam PF08447 PAS fold 165 249 1.3E-15 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAL12_RS07810 eb6ecff1594df8cd23fd5eb1c92c25ec 785 SMART SM00448 667 779 5.6E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS02175 616a03d3e4a71eedf1086fc3b514a7c1 400 Pfam PF13458 Periplasmic binding protein 27 363 1.0E-82 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS02175 616a03d3e4a71eedf1086fc3b514a7c1 400 Gene3D G3DSA:3.40.50.2300 154 325 2.9E-39 T 06-07-2017 CAL12_RS02175 616a03d3e4a71eedf1086fc3b514a7c1 400 SUPERFAMILY SSF53822 27 398 1.35E-86 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS13415 2919131de912588b61b484049a2a475c 323 PIRSF PIRSF017082 1 323 1.0E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13415 2919131de912588b61b484049a2a475c 323 Gene3D G3DSA:3.40.190.10 125 233 7.8E-4 T 06-07-2017 CAL12_RS13415 2919131de912588b61b484049a2a475c 323 SUPERFAMILY SSF53850 75 286 1.28E-16 T 06-07-2017 CAL12_RS13415 2919131de912588b61b484049a2a475c 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 319 5.4E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 SUPERFAMILY SSF54373 268 353 2.75E-9 T 06-07-2017 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 Gene3D G3DSA:3.50.50.60 109 131 4.6E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 Gene3D G3DSA:3.50.50.60 353 410 4.6E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 Gene3D G3DSA:3.50.50.60 2 59 4.6E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 Gene3D G3DSA:3.50.50.60 187 264 4.6E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 SUPERFAMILY SSF51905 108 265 6.86E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 SUPERFAMILY SSF51905 353 410 6.86E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 SUPERFAMILY SSF51905 2 55 6.86E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13915 276fa3c98b40e7b5ab1e01a2492523b0 411 Pfam PF01266 FAD dependent oxidoreductase 4 392 7.1E-53 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 SUPERFAMILY SSF52540 1 235 6.19E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 Pfam PF00005 ABC transporter 17 165 8.9E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 PIRSF PIRSF039085 1 241 6.1E-115 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 Gene3D G3DSA:3.40.50.300 1 236 4.6E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01345 482063930298160f71e399436ab1e6b5 243 SMART SM00382 26 213 1.9E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05510 b151f268e5b7992a4a1aed777cc48459 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 217 1.2E-27 T 06-07-2017 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CAL12_RS05510 b151f268e5b7992a4a1aed777cc48459 271 Gene3D G3DSA:3.40.50.300 1 246 8.2E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05510 b151f268e5b7992a4a1aed777cc48459 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 268 9.2E-103 T 06-07-2017 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 CAL12_RS05510 b151f268e5b7992a4a1aed777cc48459 271 PIRSF PIRSF003092 1 271 1.4E-90 T 06-07-2017 IPR025501 ATP binding protein MinD CAL12_RS05510 b151f268e5b7992a4a1aed777cc48459 271 SUPERFAMILY SSF52540 1 269 5.43E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 Gene3D G3DSA:3.40.50.300 6 258 1.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 300 8.7E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 Pfam PF00005 ABC transporter 27 184 9.3E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 SMART SM00382 35 234 2.3E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 SUPERFAMILY SSF52540 6 255 2.04E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02425 c4620f2ce07ae230eed0f06934f0a365 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 319 1.3E-22 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15105 ffbed897079e9aae40609cafc28f185c 683 Pfam PF01968 Hydantoinase/oxoprolinase 203 489 3.5E-87 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS15105 ffbed897079e9aae40609cafc28f185c 683 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 181 5.9E-47 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS15105 ffbed897079e9aae40609cafc28f185c 683 SUPERFAMILY SSF53067 3 76 1.4E-7 T 06-07-2017 CAL12_RS15105 ffbed897079e9aae40609cafc28f185c 683 SUPERFAMILY SSF53067 261 310 1.4E-7 T 06-07-2017 CAL12_RS24745 cdcdedc9e8fe257620596f1f85bda6b4 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.1E-46 T 06-07-2017 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CAL12_RS24745 cdcdedc9e8fe257620596f1f85bda6b4 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 06-07-2017 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CAL12_RS24745 cdcdedc9e8fe257620596f1f85bda6b4 130 SUPERFAMILY SSF54211 5 130 3.03E-46 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS24745 cdcdedc9e8fe257620596f1f85bda6b4 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.558 T 06-07-2017 IPR023035 Ribosomal protein S9, bacterial/plastid CAL12_RS24745 cdcdedc9e8fe257620596f1f85bda6b4 130 Gene3D G3DSA:3.30.230.10 6 130 1.3E-50 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 Gene3D G3DSA:1.10.10.60 302 343 5.5E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 SMART SM00342 264 347 9.6E-23 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 Gene3D G3DSA:1.10.10.60 245 301 5.1E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 Pfam PF12833 Helix-turn-helix domain 270 343 9.9E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 SUPERFAMILY SSF46689 248 298 6.91E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 SUPERFAMILY SSF46689 300 346 1.08E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20660 5eebce8ad616ea20cda1c748759099bc 354 Pfam PF06719 AraC-type transcriptional regulator N-terminus 85 235 4.6E-35 T 06-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 Gene3D G3DSA:2.170.130.10 111 260 5.6E-25 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 SUPERFAMILY SSF56935 143 785 7.33E-106 T 06-07-2017 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 Pfam PF07715 TonB-dependent Receptor Plug Domain 147 244 3.4E-14 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 149 785 3.8E-107 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 Pfam PF00593 TonB dependent receptor 552 783 1.5E-28 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 SMART SM00965 50 101 2.8E-12 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 Gene3D G3DSA:2.40.170.20 263 785 1.1E-107 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 Pfam PF07660 Secretin and TonB N terminus short domain 52 98 5.2E-9 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS04330 432097f212462594ebe0c9cd61c3ce53 785 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 768 785 - T 06-07-2017 IPR010917 TonB-dependent receptor, conserved site CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 SUPERFAMILY SSF89360 1 96 9.68E-33 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 5.0E-25 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 9.0E-38 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 4.3E-52 T 06-07-2017 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 Gene3D G3DSA:2.60.300.12 2 96 1.4E-36 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS17165 a60533295d7e320416f6936a16dd27db 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 Gene3D G3DSA:3.40.50.300 162 322 3.4E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 Pfam PF00437 Type II/IV secretion system protein 25 322 1.5E-56 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 TIGRFAM TIGR02788 VirB11: P-type DNA transfer ATPase VirB11 30 334 1.1E-93 T 06-07-2017 IPR014155 Type IV secretion system protein VirB11 GO:0005737|GO:0006810|GO:0009405 CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 Gene3D G3DSA:3.30.450.90 23 117 3.2E-21 T 06-07-2017 CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 SUPERFAMILY SSF52540 22 126 4.59E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20255 6f286c8f3fb77bedbb3af30544e80206 342 SUPERFAMILY SSF52540 156 325 4.59E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08825 76fd6cbd449bad870f4a95900a59db62 275 SUPERFAMILY SSF52096 20 274 9.52E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS08825 76fd6cbd449bad870f4a95900a59db62 275 Gene3D G3DSA:3.90.226.10 20 272 1.1E-59 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS08825 76fd6cbd449bad870f4a95900a59db62 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 273 1.3E-36 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS27975 36245ea1892be7562991c478013be4c3 90 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 69 2.0E-21 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAL12_RS27975 36245ea1892be7562991c478013be4c3 90 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 70 24.254 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAL12_RS27975 36245ea1892be7562991c478013be4c3 90 SMART SM01234 2 69 5.8E-44 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAL12_RS27975 36245ea1892be7562991c478013be4c3 90 Pfam PF01809 Haemolytic domain 3 69 8.0E-30 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAL12_RS27975 36245ea1892be7562991c478013be4c3 90 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 72 2.1E-28 T 06-07-2017 IPR002696 Putative membrane protein insertion efficiency factor CAL12_RS13975 465c1af78fb014538d735c8309daac89 271 SUPERFAMILY SSF56317 1 268 2.75E-77 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS13975 465c1af78fb014538d735c8309daac89 271 Gene3D G3DSA:3.60.110.10 1 267 2.9E-78 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS13975 465c1af78fb014538d735c8309daac89 271 Pfam PF00795 Carbon-nitrogen hydrolase 2 260 2.0E-53 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS13975 465c1af78fb014538d735c8309daac89 271 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 151 171 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAL12_RS02375 1d1af5680850f1044e0fbf784710e262 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 268 1.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02375 1d1af5680850f1044e0fbf784710e262 275 Gene3D G3DSA:1.10.3720.10 16 263 3.6E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02375 1d1af5680850f1044e0fbf784710e262 275 SUPERFAMILY SSF161098 16 265 4.06E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 SMART SM00869 1420 1678 1.0E-30 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.40.128.130 1387 1689 1.0E-47 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 877 965 2.5E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 1167 1383 3.9E-4 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 52 148 1.4E-4 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 411 612 1.3E-9 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 149 336 2.1E-14 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 613 810 3.1E-14 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Gene3D G3DSA:2.160.20.20 966 1166 9.9E-12 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 1265 1689 1.2E-28 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 SUPERFAMILY SSF51126 608 977 1.69E-29 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 255 284 1.9E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 905 934 2.5E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 720 749 1.9E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 632 661 6.2E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 536 564 1.7E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 819 848 3.7E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 167 196 4.7E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 352 381 2.8E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 1001 1030 2.0E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 71 99 3.3E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 438 467 1.1E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 1196 1223 2.0E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF12951 Passenger-associated-transport-repeat 1099 1128 1.9E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 Pfam PF03797 Autotransporter beta-domain 1422 1669 1.6E-35 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 SUPERFAMILY SSF51126 48 329 1.73E-24 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 SUPERFAMILY SSF51126 980 1337 1.57E-31 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 SUPERFAMILY SSF103515 1387 1689 2.09E-46 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 904 935 1.1E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 69 100 3.2E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 719 750 4.2E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 166 197 3.5E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 438 468 9.3E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 818 849 2.5E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1000 1031 4.8E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1098 1128 2.8E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 351 382 7.0E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 631 662 1.1E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 254 285 7.5E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1195 1226 1.3E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21065 ed29d3d90e2c96698e2c334ef37a7c7e 1689 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 535 565 2.0E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 SMART SM00418 8 89 4.5E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 5.4E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 5.4E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 5.4E-6 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 Gene3D G3DSA:1.10.10.10 4 93 5.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 Pfam PF12840 Helix-turn-helix domain 10 69 9.6E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21170 059f507041d648632c99a91f9975b4ef 109 SUPERFAMILY SSF46785 5 93 3.68E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20605 7624fbb492b01aace0cee4f1af71a127 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 323 5.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20605 7624fbb492b01aace0cee4f1af71a127 328 SUPERFAMILY SSF53850 118 290 1.33E-14 T 06-07-2017 CAL12_RS20605 7624fbb492b01aace0cee4f1af71a127 328 PIRSF PIRSF017082 1 328 8.9E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 Pfam PF00043 Glutathione S-transferase, C-terminal domain 182 251 4.5E-9 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 SUPERFAMILY SSF47616 182 260 1.13E-34 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 SUPERFAMILY SSF47616 118 153 1.13E-34 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 SUPERFAMILY SSF52833 39 131 1.02E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 Pfam PF02798 Glutathione S-transferase, N-terminal domain 46 128 8.3E-8 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 Gene3D G3DSA:3.40.30.10 34 131 2.8E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS04315 be88b7b5d39528c98a36ac7661b99eb9 292 Gene3D G3DSA:1.20.1050.10 132 255 2.2E-44 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 SUPERFAMILY SSF50129 4 163 3.65E-53 T 06-07-2017 IPR011032 GroES-like CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 SMART SM00829 14 335 5.0E-7 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 Gene3D G3DSA:3.40.50.720 171 284 2.4E-21 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 Pfam PF00107 Zinc-binding dehydrogenase 177 299 1.9E-20 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 SUPERFAMILY SSF51735 140 301 8.05E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 134 1.4E-30 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS13105 08a1ae79dd584e51b49f89472b73567f 339 Gene3D G3DSA:3.90.180.10 1 170 5.5E-63 T 06-07-2017 IPR011032 GroES-like CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 SUPERFAMILY SSF54975 1 124 6.54E-32 T 06-07-2017 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 Gene3D G3DSA:3.20.20.450 173 390 5.0E-50 T 06-07-2017 IPR001633 EAL domain CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 SUPERFAMILY SSF141868 172 391 3.53E-54 T 06-07-2017 IPR001633 EAL domain CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 Pfam PF04940 Sensors of blue-light using FAD 2 92 4.0E-24 T 06-07-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 Pfam PF00563 EAL domain 174 389 9.1E-50 T 06-07-2017 IPR001633 EAL domain CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 SMART SM01034 2 94 2.3E-31 T 06-07-2017 IPR007024 BLUF domain GO:0009882|GO:0071949 CAL12_RS13375 5809c7fb37bb74e716c45e8504670132 404 SMART SM00052 144 394 8.6E-41 T 06-07-2017 IPR001633 EAL domain CAL12_RS25945 5ab4e73e450af27763e8a4d723d3c94b 218 Gene3D G3DSA:1.10.3720.10 8 208 1.3E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25945 5ab4e73e450af27763e8a4d723d3c94b 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 104 9.0E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS25945 5ab4e73e450af27763e8a4d723d3c94b 218 SUPERFAMILY SSF161098 9 206 1.01E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25945 5ab4e73e450af27763e8a4d723d3c94b 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 207 2.8E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 Pfam PF02381 MraZ protein, putative antitoxin-like 79 127 8.5E-12 T 06-07-2017 IPR020603 MraZ domain CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 Pfam PF02381 MraZ protein, putative antitoxin-like 8 75 5.4E-13 T 06-07-2017 IPR020603 MraZ domain CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 148 48.765 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 7 123 5.0E-55 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 8 145 1.3E-34 T 06-07-2017 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CAL12_RS22450 e28ae800b33286c7cd1fb42fb5aefe0e 148 SUPERFAMILY SSF89447 6 135 6.58E-38 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 SUPERFAMILY SSF53067 156 337 2.25E-48 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 SUPERFAMILY SSF53067 9 153 2.75E-37 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 Pfam PF06723 MreB/Mbl protein 11 340 4.9E-147 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 6.0E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 6.0E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 6.0E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 6.0E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 6.0E-62 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 Gene3D G3DSA:3.90.640.10 192 264 3.1E-28 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 Gene3D G3DSA:3.30.420.40 268 322 4.4E-35 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 Gene3D G3DSA:3.30.420.40 165 191 4.4E-35 T 06-07-2017 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 2.1E-153 T 06-07-2017 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 CAL12_RS25305 2c6529ffeecb198e0c8a18e880808fa0 347 Gene3D G3DSA:3.30.420.40 10 164 2.1E-43 T 06-07-2017 CAL12_RS10030 e705e2b765a912a8b77748a133e4ff6d 289 SUPERFAMILY SSF51556 8 289 1.6E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS10030 e705e2b765a912a8b77748a133e4ff6d 289 Pfam PF04909 Amidohydrolase 12 289 1.3E-41 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS10030 e705e2b765a912a8b77748a133e4ff6d 289 Gene3D G3DSA:3.20.20.140 3 289 1.3E-92 T 06-07-2017 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 SUPERFAMILY SSF47240 1 155 1.83E-53 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PIRSF PIRSF002560 1 157 9.2E-73 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 3 22 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 23 43 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 86 106 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 128 149 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 44 64 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 65 85 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 PRINTS PR00601 Bacterioferritin signature 107 127 7.1E-67 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 Gene3D G3DSA:1.20.1260.10 1 155 2.4E-64 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 Pfam PF00210 Ferritin-like domain 9 142 1.6E-39 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAL12_RS00680 240bd2a116b2004b62f97cfb1f844016 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.4E-74 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS23000 0b075f9e8bb18ccbc6e5ea1b35745394 323 Pfam PF00534 Glycosyl transferases group 1 205 296 4.8E-11 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS23000 0b075f9e8bb18ccbc6e5ea1b35745394 323 Gene3D G3DSA:3.40.50.2000 204 296 5.7E-7 T 06-07-2017 CAL12_RS23000 0b075f9e8bb18ccbc6e5ea1b35745394 323 SUPERFAMILY SSF53756 36 320 2.41E-25 T 06-07-2017 CAL12_RS25425 0729b93849b825a5871db0a45de415f4 89 SUPERFAMILY SSF47413 5 72 1.98E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25425 0729b93849b825a5871db0a45de415f4 89 Gene3D G3DSA:1.10.260.40 4 65 5.5E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25425 0729b93849b825a5871db0a45de415f4 89 Pfam PF13560 Helix-turn-helix domain 5 66 3.0E-8 T 06-07-2017 CAL12_RS25425 0729b93849b825a5871db0a45de415f4 89 SMART SM00530 9 66 5.8E-6 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS14565 cae9b4e1d338fd16746e5f3150464454 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 1.2E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14565 cae9b4e1d338fd16746e5f3150464454 322 PIRSF PIRSF017082 1 320 1.3E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14565 cae9b4e1d338fd16746e5f3150464454 322 SUPERFAMILY SSF53850 97 279 1.71E-12 T 06-07-2017 CAL12_RS12510 a6fb232649b0e0bdd01e923ce55dd25b 238 SUPERFAMILY SSF46689 18 82 1.25E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12510 a6fb232649b0e0bdd01e923ce55dd25b 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 70 1.9E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS12510 a6fb232649b0e0bdd01e923ce55dd25b 238 Gene3D G3DSA:1.10.10.60 12 56 8.0E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12510 a6fb232649b0e0bdd01e923ce55dd25b 238 Gene3D G3DSA:1.10.357.10 57 151 2.6E-9 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS15715 88818792ccd9858eaea54b465d12d451 416 SUPERFAMILY SSF53822 27 410 5.89E-78 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS15715 88818792ccd9858eaea54b465d12d451 416 Gene3D G3DSA:3.40.50.2300 173 323 1.4E-26 T 06-07-2017 CAL12_RS15715 88818792ccd9858eaea54b465d12d451 416 Pfam PF13458 Periplasmic binding protein 27 382 6.7E-55 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS15715 88818792ccd9858eaea54b465d12d451 416 Gene3D G3DSA:3.40.50.2300 324 379 3.5E-49 T 06-07-2017 CAL12_RS15715 88818792ccd9858eaea54b465d12d451 416 Gene3D G3DSA:3.40.50.2300 22 166 3.5E-49 T 06-07-2017 CAL12_RS26720 0d8b9ac6fc2ddb6a93fe356388bc1f23 244 SMART SM00382 36 213 1.5E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26720 0d8b9ac6fc2ddb6a93fe356388bc1f23 244 Pfam PF00005 ABC transporter 28 169 7.2E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26720 0d8b9ac6fc2ddb6a93fe356388bc1f23 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS26720 0d8b9ac6fc2ddb6a93fe356388bc1f23 244 SUPERFAMILY SSF52540 12 231 2.47E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26720 0d8b9ac6fc2ddb6a93fe356388bc1f23 244 Gene3D G3DSA:3.40.50.300 11 239 1.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 411 4.6E-167 T 06-07-2017 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Gene3D G3DSA:4.10.320.10 117 164 2.6E-12 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Pfam PF02817 e3 binding domain 119 153 9.2E-11 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 06-07-2017 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Gene3D G3DSA:3.30.559.10 180 410 1.2E-89 T 06-07-2017 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 182 410 1.4E-79 T 06-07-2017 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 SUPERFAMILY SSF51230 2 96 3.4E-25 T 06-07-2017 IPR011053 Single hybrid motif CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Pfam PF00364 Biotin-requiring enzyme 5 77 3.5E-20 T 06-07-2017 IPR000089 Biotin/lipoyl attachment CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 Gene3D G3DSA:2.40.50.100 2 96 4.9E-28 T 06-07-2017 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 SUPERFAMILY SSF52777 182 411 2.49E-86 T 06-07-2017 CAL12_RS19220 7342f2afca6c00fa70706a1daebc3ad3 412 SUPERFAMILY SSF47005 113 155 1.7E-8 T 06-07-2017 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 Gene3D G3DSA:2.40.50.100 73 101 3.3E-16 T 06-07-2017 CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 Gene3D G3DSA:2.40.50.100 232 265 3.3E-16 T 06-07-2017 CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 SUPERFAMILY SSF111369 191 287 5.23E-12 T 06-07-2017 CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 172 312 5.2E-18 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 Pfam PF13533 Biotin-lipoyl like 73 115 1.9E-10 T 06-07-2017 CAL12_RS01615 a17a3432beabbea92739327866ba16ff 367 SUPERFAMILY SSF111369 71 148 1.57E-6 T 06-07-2017 CAL12_RS09545 581b56c0b170e13363b3d0329c1816c9 231 Gene3D G3DSA:3.90.850.10 20 231 1.7E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS09545 581b56c0b170e13363b3d0329c1816c9 231 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 231 2.9E-51 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS09545 581b56c0b170e13363b3d0329c1816c9 231 SUPERFAMILY SSF56529 20 231 8.5E-68 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 SMART SM00479 2 174 5.4E-46 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 5 212 2.7E-55 T 06-07-2017 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 Pfam PF00929 Exonuclease 4 160 2.3E-33 T 06-07-2017 IPR013520 Exonuclease, RNase T/DNA polymerase III CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 SUPERFAMILY SSF53098 1 175 3.29E-52 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 Gene3D G3DSA:3.30.420.10 1 173 2.6E-61 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS24230 13064bbe2886455b5f4c69aca080be8c 248 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 233 1.2E-86 T 06-07-2017 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 SMART SM00304 177 229 7.9E-5 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 7.1E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 7.1E-6 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Pfam PF00672 HAMP domain 162 224 2.3E-6 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 SMART SM00388 230 295 1.8E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Pfam PF08521 Two-component sensor kinase N-terminal 17 149 5.2E-8 T 06-07-2017 IPR013727 Two-component sensor kinase, N-terminal CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Gene3D G3DSA:3.30.565.10 283 431 1.3E-24 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 SUPERFAMILY SSF47384 213 295 3.34E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Gene3D G3DSA:1.20.5.1040 3 63 3.3E-4 T 06-07-2017 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Gene3D G3DSA:1.20.5.1040 105 178 4.1E-12 T 06-07-2017 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Gene3D G3DSA:1.10.287.130 223 282 8.0E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 SUPERFAMILY SSF55874 285 431 3.54E-26 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 SMART SM00387 344 452 3.5E-23 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 294 1.9E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS14255 fb59fe92c8f31f5602e4fea174d914b4 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 431 9.4E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 112 333 2.8E-51 T 06-07-2017 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 Gene3D G3DSA:3.40.710.10 112 351 5.2E-61 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 218 231 1.1E-11 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 152 1.1E-11 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 191 208 1.1E-11 T 06-07-2017 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 SUPERFAMILY SSF56601 25 45 1.41E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS25985 31384f0de760c02e1c851772dffb1114 372 SUPERFAMILY SSF56601 113 346 1.41E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS26120 c72d0f735d6438578aae3fe34d0a5ea7 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 3.0E-91 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAL12_RS26120 c72d0f735d6438578aae3fe34d0a5ea7 262 Gene3D G3DSA:3.20.20.70 1 261 4.1E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS26120 c72d0f735d6438578aae3fe34d0a5ea7 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 06-07-2017 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CAL12_RS26120 c72d0f735d6438578aae3fe34d0a5ea7 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 34.954 T 06-07-2017 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CAL12_RS26120 c72d0f735d6438578aae3fe34d0a5ea7 262 SUPERFAMILY SSF51366 12 261 8.59E-88 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 SUPERFAMILY SSF46911 14 89 5.58E-28 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 36 87 3.0E-21 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 87 2.0E-33 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 Pfam PF01084 Ribosomal protein S18 33 83 2.7E-23 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 PRINTS PR00974 Ribosomal protein S18 family signature 53 60 1.3E-15 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 PRINTS PR00974 Ribosomal protein S18 family signature 75 85 1.3E-15 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 PRINTS PR00974 Ribosomal protein S18 family signature 43 53 1.3E-15 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 PRINTS PR00974 Ribosomal protein S18 family signature 61 75 1.3E-15 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 36 59 - T 06-07-2017 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 Gene3D G3DSA:4.10.640.10 23 89 7.6E-31 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18280 e5aac2f108c486f4c8ae1c85f9e7401f 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 88 20.503 T 06-07-2017 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 SUPERFAMILY SSF52540 7 240 4.7E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 Gene3D G3DSA:3.40.50.300 3 222 2.8E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 SMART SM00382 36 232 2.1E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 Pfam PF09821 C-terminal AAA-associated domain 302 420 3.7E-36 T 06-07-2017 IPR018632 C-terminal AAA-associated domain CAL12_RS12360 be81aae5ef01207a5a2482779abcfa3b 434 Pfam PF00005 ABC transporter 27 166 1.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 Gene3D G3DSA:1.20.1560.10 14 343 6.6E-13 T 06-07-2017 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 ProSitePatterns PS00211 ABC transporters family signature. 510 524 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 Gene3D G3DSA:3.40.50.300 384 572 1.5E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 SUPERFAMILY SSF90123 14 343 7.19E-23 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 Pfam PF00005 ABC transporter 383 538 1.7E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 SMART SM00382 388 585 3.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 Pfam PF06472 ABC transporter transmembrane region 2 12 297 7.9E-60 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS12435 2341de2ca618c7f06ffcc9e3b0fff699 596 SUPERFAMILY SSF52540 383 574 1.19E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 SUPERFAMILY SSF51735 136 319 1.17E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 169 194 - T 06-07-2017 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 SMART SM01002 145 314 3.9E-84 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 SMART SM01003 4 136 5.3E-58 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.4E-37 T 06-07-2017 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 Gene3D G3DSA:3.40.50.1770 187 368 4.2E-42 T 06-07-2017 CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 370 1.6E-73 T 06-07-2017 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 SUPERFAMILY SSF52283 1 167 1.79E-46 T 06-07-2017 CAL12_RS17745 5a642dd3d4831563fedc8471f81e0dc9 372 Gene3D G3DSA:3.40.50.1770 2 186 1.1E-55 T 06-07-2017 CAL12_RS09060 54b3069a1c7a45a84fd17585e6a89720 1249 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 358 1229 6.2E-197 T 06-07-2017 IPR011836 Conserved hypothetical protein CHP02099 CAL12_RS09060 54b3069a1c7a45a84fd17585e6a89720 1249 Pfam PF13502 AsmA-like C-terminal region 990 1225 1.7E-51 T 06-07-2017 IPR032712 AsmA-like, C-terminal CAL12_RS09060 54b3069a1c7a45a84fd17585e6a89720 1249 Pfam PF13116 Protein of unknown function 445 730 4.8E-42 T 06-07-2017 IPR025263 Domain of unknown function DUF3971 CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 Gene3D G3DSA:1.20.1250.20 273 442 6.8E-20 T 06-07-2017 CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 Gene3D G3DSA:1.20.1250.20 25 207 3.8E-30 T 06-07-2017 CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 Pfam PF07690 Major Facilitator Superfamily 29 422 2.1E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 SUPERFAMILY SSF103473 260 432 6.41E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 SUPERFAMILY SSF103473 14 205 6.41E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09360 f6f1559d6c43a2c9cbca84d33044028b 533 SUPERFAMILY SSF103473 492 518 6.41E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19250 4613ff41e2181949415bf353521561c1 86 SUPERFAMILY SSF109910 4 80 9.15E-19 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAL12_RS19250 4613ff41e2181949415bf353521561c1 86 Pfam PF03937 Flavinator of succinate dehydrogenase 9 69 5.5E-20 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAL12_RS19250 4613ff41e2181949415bf353521561c1 86 Gene3D G3DSA:1.10.150.250 6 84 2.1E-22 T 06-07-2017 IPR005631 Flavinator of succinate dehydrogenase CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Pfam PF04073 Aminoacyl-tRNA editing domain 257 382 3.8E-27 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 575 40.302 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 SUPERFAMILY SSF55681 411 482 7.08E-100 T 06-07-2017 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 SUPERFAMILY SSF55681 10 237 7.08E-100 T 06-07-2017 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 SUPERFAMILY SSF52954 468 576 2.13E-29 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 463 7.1E-45 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 PIRSF PIRSF001535 1 577 5.4E-261 T 06-07-2017 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 1.3E-220 T 06-07-2017 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Pfam PF03129 Anticodon binding domain 480 571 1.2E-15 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Gene3D G3DSA:3.90.960.10 239 392 7.4E-29 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 SUPERFAMILY SSF55826 218 393 1.57E-30 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.6E-18 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.6E-18 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.6E-18 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.6E-18 T 06-07-2017 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Gene3D G3DSA:3.30.930.10 7 204 4.9E-102 T 06-07-2017 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Gene3D G3DSA:3.30.930.10 396 472 4.9E-102 T 06-07-2017 CAL12_RS22615 de58a1092cbbf8bae08b698a8d438587 577 Gene3D G3DSA:3.40.50.800 475 576 1.1E-28 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 PIRSF PIRSF029827 1 90 1.1E-40 T 06-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 7.0E-35 T 06-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.913 T 06-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 SUPERFAMILY SSF111148 1 89 1.83E-38 T 06-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 1.6E-41 T 06-07-2017 IPR007457 Fe(II) trafficking protein YggX GO:0005506 CAL12_RS18020 3bd38f41d3387a278aede601134c46d9 90 Gene3D G3DSA:1.10.3880.10 1 89 3.8E-40 T 06-07-2017 CAL12_RS25445 5afa213ce7a3510b8849238dd2c9897a 418 Gene3D G3DSA:1.10.10.10 254 347 1.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25445 5afa213ce7a3510b8849238dd2c9897a 418 Gene3D G3DSA:3.40.50.2300 7 120 6.5E-4 T 06-07-2017 CAL12_RS25445 5afa213ce7a3510b8849238dd2c9897a 418 SUPERFAMILY SSF52172 5 120 2.05E-5 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 Gene3D G3DSA:3.30.40.10 137 166 9.5E-4 T 06-07-2017 IPR013083 Zinc finger, RING/FYVE/PHD-type CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 Pfam PF00664 ABC transporter transmembrane region 185 458 7.1E-46 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 Gene3D G3DSA:3.40.50.300 507 736 2.4E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 Gene3D G3DSA:1.20.1560.10 173 487 4.5E-82 T 06-07-2017 CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 SMART SM00382 532 718 2.8E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 Pfam PF00005 ABC transporter 524 672 9.9E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 SUPERFAMILY SSF52540 497 742 1.44E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19110 eba4222af8a8955cae615bec7bbc7935 767 SUPERFAMILY SSF90123 173 487 7.06E-76 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS25040 1dc317773a5145ca0bfa35bfd78997a6 289 Gene3D G3DSA:3.40.50.300 35 276 7.6E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25040 1dc317773a5145ca0bfa35bfd78997a6 289 SMART SM00382 61 255 6.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25040 1dc317773a5145ca0bfa35bfd78997a6 289 Pfam PF00005 ABC transporter 53 209 4.1E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25040 1dc317773a5145ca0bfa35bfd78997a6 289 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 256 278 5.3E-12 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS25040 1dc317773a5145ca0bfa35bfd78997a6 289 SUPERFAMILY SSF52540 35 279 4.13E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10020 44fec14ce478714c708cf570e6c81674 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 329 3.5E-91 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10020 44fec14ce478714c708cf570e6c81674 332 PIRSF PIRSF017082 2 332 5.9E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10020 44fec14ce478714c708cf570e6c81674 332 SUPERFAMILY SSF53850 121 298 8.14E-12 T 06-07-2017 CAL12_RS11710 36a8fb3324466dd464cc4ed833a9ae5d 83 Pfam PF04226 Transglycosylase associated protein 33 80 1.2E-16 T 06-07-2017 IPR007341 Transglycosylase-associated protein GO:0016021 CAL12_RS11710 36a8fb3324466dd464cc4ed833a9ae5d 83 Gene3D G3DSA:1.10.3470.10 9 75 1.0E-4 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS08760 cff693151e52697eab8fe18f39d323e9 274 Pfam PF04909 Amidohydrolase 10 273 1.5E-29 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS08760 cff693151e52697eab8fe18f39d323e9 274 Gene3D G3DSA:3.20.20.140 6 273 3.6E-64 T 06-07-2017 CAL12_RS08760 cff693151e52697eab8fe18f39d323e9 274 SUPERFAMILY SSF51556 7 273 1.13E-52 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 SUPERFAMILY SSF56024 182 346 2.0E-40 T 06-07-2017 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 Hamap MF_01917 Cardiolipin synthase B [clsB]. 2 383 50.344 T 06-07-2017 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 Gene3D G3DSA:3.30.870.10 208 353 4.1E-32 T 06-07-2017 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 Gene3D G3DSA:3.30.870.10 2 182 2.2E-41 T 06-07-2017 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 SMART SM00155 108 135 6.1E-8 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 SMART SM00155 285 312 11.0 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 SUPERFAMILY SSF56024 3 167 3.34E-39 T 06-07-2017 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 Pfam PF13091 PLD-like domain 214 338 1.5E-27 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS08590 643b146be9e3575a4fc6acba349f8aff 409 Pfam PF13091 PLD-like domain 26 154 1.9E-16 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 SUPERFAMILY SSF55729 206 334 2.84E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 Pfam PF00583 Acetyltransferase (GNAT) family 252 328 8.9E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 SMART SM00347 34 134 2.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 Pfam PF12802 MarR family 39 98 9.6E-13 T 06-07-2017 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 SUPERFAMILY SSF46785 12 149 9.63E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 4.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 4.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 4.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 Gene3D G3DSA:3.40.630.30 202 343 3.3E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS23845 6d3c8ba71ff1279dad052bda2c7555af 356 Gene3D G3DSA:1.10.10.10 5 148 1.1E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06050 7562312d3874dbb7616c146b375da635 339 Pfam PF00639 PPIC-type PPIASE domain 196 280 7.1E-17 T 06-07-2017 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 CAL12_RS06050 7562312d3874dbb7616c146b375da635 339 SUPERFAMILY SSF54534 178 284 9.81E-24 T 06-07-2017 CAL12_RS06050 7562312d3874dbb7616c146b375da635 339 Gene3D G3DSA:3.10.50.40 176 306 7.3E-30 T 06-07-2017 CAL12_RS06050 7562312d3874dbb7616c146b375da635 339 SUPERFAMILY SSF109998 68 208 1.29E-6 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 27.682 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 9.4E-46 T 06-07-2017 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 SUPERFAMILY SSF54862 36 145 2.22E-24 T 06-07-2017 CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 2.2E-11 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS19670 390fd9c8df17d1a7ef1091e840db0012 162 Gene3D G3DSA:1.10.1060.10 16 128 6.1E-22 T 06-07-2017 CAL12_RS10355 2405734e1c2f96a7ed961b1749fef91b 287 SUPERFAMILY SSF55961 1 150 3.38E-20 T 06-07-2017 CAL12_RS10355 2405734e1c2f96a7ed961b1749fef91b 287 Gene3D G3DSA:3.30.530.20 1 154 3.1E-23 T 06-07-2017 IPR023393 START-like domain CAL12_RS10355 2405734e1c2f96a7ed961b1749fef91b 287 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 10 150 3.5E-14 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 Gene3D G3DSA:3.90.850.10 130 426 4.5E-87 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 Pfam PF09298 Fumarylacetoacetase N-terminal 28 127 4.6E-24 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 13 432 1.3E-138 T 06-07-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 Gene3D G3DSA:2.30.30.230 13 129 2.3E-32 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 SUPERFAMILY SSF63433 12 127 1.44E-31 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 133 430 2.2E-49 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14875 7444553e5a14c61201403ad4d17b6d35 439 SUPERFAMILY SSF56529 130 432 5.1E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS11670 521ab979b5ba34b42464af62a67817b3 195 Pfam PF00881 Nitroreductase family 10 168 3.9E-26 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAL12_RS11670 521ab979b5ba34b42464af62a67817b3 195 SUPERFAMILY SSF55469 6 188 1.96E-36 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS11670 521ab979b5ba34b42464af62a67817b3 195 Gene3D G3DSA:3.40.109.10 7 189 9.5E-39 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS11670 521ab979b5ba34b42464af62a67817b3 195 PIRSF PIRSF000232 2 192 1.3E-51 T 06-07-2017 IPR026021 Putative NAD(P)H nitroreductase YdjA-like CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 Gene3D G3DSA:1.10.10.10 3 83 3.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 Gene3D G3DSA:3.40.190.10 219 268 9.0E-6 T 06-07-2017 CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 Pfam PF03466 LysR substrate binding domain 92 302 1.3E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 Gene3D G3DSA:3.40.190.10 84 205 4.0E-13 T 06-07-2017 CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 SUPERFAMILY SSF53850 93 300 1.05E-22 T 06-07-2017 CAL12_RS10615 203183905a61ae840b818568732d9bf2 304 SUPERFAMILY SSF46785 2 112 3.86E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 Gene3D G3DSA:3.40.1080.10 3 240 9.9E-61 T 06-07-2017 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 Pfam PF01144 Coenzyme A transferase 5 240 1.6E-31 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 SUPERFAMILY SSF100950 271 511 3.23E-68 T 06-07-2017 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 SMART SM00882 3 241 2.5E-46 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 PIRSF PIRSF000858 1 517 2.8E-192 T 06-07-2017 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 Gene3D G3DSA:3.40.810.20 270 505 7.3E-54 T 06-07-2017 CAL12_RS03230 f9d23635b8068dd456ca55a61adc6d34 534 SUPERFAMILY SSF100950 3 254 5.19E-79 T 06-07-2017 CAL12_RS10570 5449039b5528c96c1f51a1cfe7d36196 313 SMART SM01130 5 306 3.2E-63 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS10570 5449039b5528c96c1f51a1cfe7d36196 313 Gene3D G3DSA:3.20.20.70 6 311 1.2E-71 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS10570 5449039b5528c96c1f51a1cfe7d36196 313 SUPERFAMILY SSF51569 4 308 3.04E-64 T 06-07-2017 CAL12_RS10570 5449039b5528c96c1f51a1cfe7d36196 313 Pfam PF00701 Dihydrodipicolinate synthetase family 7 304 1.2E-39 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS10570 5449039b5528c96c1f51a1cfe7d36196 313 PIRSF PIRSF001365 1 312 8.3E-56 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Gene3D G3DSA:1.10.760.10 372 476 9.6E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 SUPERFAMILY SSF46626 247 358 7.83E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 SUPERFAMILY SSF46626 71 197 1.05E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 SUPERFAMILY SSF46626 372 475 1.72E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Gene3D G3DSA:1.10.760.10 73 174 1.9E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Gene3D G3DSA:1.10.760.10 245 353 7.3E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Pfam PF00034 Cytochrome c 77 174 1.0E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Pfam PF00034 Cytochrome c 247 353 2.1E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01700 5f60e64da9aa8cf54270436e05286f02 478 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 369 454 7.3E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SUPERFAMILY SSF52821 113 241 2.49E-29 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Gene3D G3DSA:3.40.250.10 269 364 2.7E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SUPERFAMILY SSF52821 10 127 8.51E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SMART SM00450 15 112 2.4E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SMART SM00450 275 371 2.7E-4 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SMART SM00450 138 236 1.8E-6 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SMART SM00450 382 475 0.77 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Gene3D G3DSA:3.40.250.10 375 482 1.5E-12 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SUPERFAMILY SSF52821 264 364 7.33E-22 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Pfam PF00581 Rhodanese-like domain 16 108 5.7E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Pfam PF00581 Rhodanese-like domain 138 232 1.6E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Pfam PF00581 Rhodanese-like domain 281 364 1.3E-6 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Gene3D G3DSA:3.40.250.10 9 122 1.5E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 Gene3D G3DSA:3.40.250.10 133 244 5.8E-18 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS07480 149eb07ebf94be3019f3c8e846764fd5 537 SUPERFAMILY SSF52821 380 524 7.46E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 Gene3D G3DSA:3.40.50.720 8 253 2.6E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 SUPERFAMILY SSF51735 6 255 1.48E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 5.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 5.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 5.8E-18 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 Pfam PF00106 short chain dehydrogenase 8 195 3.4E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 188 2.5E-4 T 06-07-2017 CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14230 589bfc7ef4edad263e318f2e20e06ca3 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.4E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 PIRSF PIRSF000124 1 443 1.9E-149 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Gene3D G3DSA:3.40.50.720 235 443 7.2E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Gene3D G3DSA:3.40.50.720 1 206 1.9E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 5.8E-67 T 06-07-2017 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 SUPERFAMILY SSF52413 306 438 6.93E-37 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Gene3D G3DSA:1.20.5.100 207 232 4.0E-18 T 06-07-2017 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 424 1.2E-138 T 06-07-2017 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 SMART SM00984 320 428 1.8E-49 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 SUPERFAMILY SSF51735 1 194 6.04E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 PIRSF PIRSF500134 1 444 1.7E-189 T 06-07-2017 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 4.4E-38 T 06-07-2017 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 427 9.1E-31 T 06-07-2017 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CAL12_RS01065 d8a269541a1d6a888da641b5902fc9bb 444 SUPERFAMILY SSF48179 204 298 3.95E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 SMART SM00116 79 126 6.9E-4 T 06-07-2017 IPR000644 CBS domain CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 SMART SM00116 14 61 0.036 T 06-07-2017 IPR000644 CBS domain CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 Pfam PF00571 CBS domain 16 60 3.3E-6 T 06-07-2017 IPR000644 CBS domain CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 Pfam PF00571 CBS domain 73 126 4.0E-9 T 06-07-2017 IPR000644 CBS domain CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 SUPERFAMILY SSF54631 2 131 5.18E-27 T 06-07-2017 CAL12_RS09615 ef78a796d83e6507ef185f282276042f 155 Gene3D G3DSA:3.10.580.10 4 127 9.5E-26 T 06-07-2017 CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 SUPERFAMILY SSF63829 41 302 2.14E-64 T 06-07-2017 CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 283 5.4E-45 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 Gene3D G3DSA:2.120.10.30 44 303 4.3E-64 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 3.5E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 3.5E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS09900 4b322cada5e187c6682522991f37e1da 306 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 3.5E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF00207 Alpha-2-macroglobulin family 1033 1114 1.2E-10 T 06-07-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 827 963 3.6E-11 T 06-07-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 SMART SM01359 819 963 7.4E-34 T 06-07-2017 IPR011625 Alpha-2-macroglobulin, N-terminal 2 CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 359 452 6.6E-22 T 06-07-2017 IPR021868 Alpha-2-macroglobulin MG1 domain CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 SUPERFAMILY SSF48239 1232 1516 8.3E-40 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF07678 A-macroglobulin complement component 1283 1365 1.0E-6 T 06-07-2017 IPR011626 Alpha-macroglobulin complement component GO:0005615 CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 PIRSF PIRSF038980 8 1736 0.0 T 06-07-2017 IPR026284 Alpha-2-macroglobulin domain protein, bacteria CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1233 1252 1.2E-4 T 06-07-2017 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 SMART SM01360 1025 1114 5.9E-28 T 06-07-2017 IPR001599 Alpha-2-macroglobulin GO:0004866 CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Gene3D G3DSA:1.50.10.20 1232 1515 4.0E-34 T 06-07-2017 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CAL12_RS17395 0a7f3d32e08ddb63516f3faa0cfdab86 1741 Pfam PF01835 MG2 domain 459 556 5.3E-18 T 06-07-2017 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 3.3E-37 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 SUPERFAMILY SSF51735 6 162 8.71E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 160 8.5E-39 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 Gene3D G3DSA:1.10.1040.10 165 295 2.2E-38 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 Gene3D G3DSA:3.40.50.720 3 163 6.1E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 SUPERFAMILY SSF48179 166 294 1.36E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS27205 7d0c864242f90ffd160fdbb72e18b606 302 PIRSF PIRSF000103 1 295 7.2E-66 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 Gene3D G3DSA:3.40.50.720 18 197 4.0E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 SUPERFAMILY SSF51735 16 339 1.69E-83 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 Gene3D G3DSA:3.90.25.10 198 324 3.9E-33 T 06-07-2017 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 1.6E-6 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 PRINTS PR01713 Nucleotide sugar epimerase signature 258 273 1.6E-6 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 PRINTS PR01713 Nucleotide sugar epimerase signature 45 61 1.6E-6 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 1.6E-6 T 06-07-2017 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS02705 56c0547c0db9d166c9130d7c8e89da27 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 264 2.1E-55 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS23115 c5afe2794055c22f94b38d3ff5bed3a6 321 SUPERFAMILY SSF56317 9 306 2.09E-76 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS23115 c5afe2794055c22f94b38d3ff5bed3a6 321 Gene3D G3DSA:3.60.110.10 8 305 2.7E-76 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS23115 c5afe2794055c22f94b38d3ff5bed3a6 321 Pfam PF00795 Carbon-nitrogen hydrolase 12 285 1.7E-51 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 SUPERFAMILY SSF50346 150 238 9.42E-11 T 06-07-2017 IPR011033 PRC-barrel-like CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Pfam PF05239 PRC-barrel domain 147 231 1.9E-4 T 06-07-2017 IPR027275 PRC-barrel domain CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 14 239 23.157 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Gene3D G3DSA:2.30.30.240 150 239 1.2E-19 T 06-07-2017 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Gene3D G3DSA:2.40.30.60 10 47 1.6E-10 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Gene3D G3DSA:2.40.30.60 66 144 4.9E-14 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Pfam PF01782 RimM N-terminal domain 68 141 5.8E-11 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 Pfam PF01782 RimM N-terminal domain 16 44 7.4E-7 T 06-07-2017 IPR002676 RimM protein GO:0006364 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 SUPERFAMILY SSF50447 97 143 3.18E-7 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 104 238 1.2E-27 T 06-07-2017 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CAL12_RS09190 db4605e98cddd368eeb407cda07d79c2 239 SUPERFAMILY SSF50447 13 45 3.35E-5 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 Gene3D G3DSA:1.10.10.10 2 70 2.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 Gene3D G3DSA:3.40.1410.10 82 236 4.1E-28 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 SMART SM00866 89 234 3.4E-14 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.2E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 Pfam PF07702 UTRA domain 91 233 4.8E-17 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 8.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 8.6E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 SUPERFAMILY SSF64288 55 241 4.08E-31 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 SUPERFAMILY SSF46785 3 71 2.73E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13100 7414b5fd7951e364b59c867f4d9dbca5 247 SMART SM00345 8 67 2.2E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 SMART SM00347 60 160 2.8E-20 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 SUPERFAMILY SSF46785 39 176 1.17E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 Gene3D G3DSA:1.10.10.10 38 172 1.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 Pfam PF01047 MarR family 67 124 4.8E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 101 116 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 150 170 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12810 f30f41376a4e7403d61ddce823de2033 185 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 136 1.0E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS04035 af1be2c9a392974a8439b75acc367883 440 Pfam PF07690 Major Facilitator Superfamily 266 431 9.3E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS04035 af1be2c9a392974a8439b75acc367883 440 Pfam PF00083 Sugar (and other) transporter 25 241 1.7E-24 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS04035 af1be2c9a392974a8439b75acc367883 440 Gene3D G3DSA:1.20.1250.20 245 433 5.6E-22 T 06-07-2017 CAL12_RS04035 af1be2c9a392974a8439b75acc367883 440 Gene3D G3DSA:1.20.1250.20 22 224 7.5E-23 T 06-07-2017 CAL12_RS04035 af1be2c9a392974a8439b75acc367883 440 SUPERFAMILY SSF103473 22 435 1.7E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS14035 e4f0cbf771eb606ebed517ffd93850bb 344 SUPERFAMILY SSF51569 18 317 2.75E-58 T 06-07-2017 CAL12_RS14035 e4f0cbf771eb606ebed517ffd93850bb 344 Gene3D G3DSA:3.20.20.70 19 310 1.8E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS14035 e4f0cbf771eb606ebed517ffd93850bb 344 Pfam PF00682 HMGL-like 20 297 1.6E-37 T 06-07-2017 IPR000891 Pyruvate carboxyltransferase GO:0003824 CAL12_RS01170 196aec2902bfff8aec63e8e1864d9c64 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 2.0E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01170 196aec2902bfff8aec63e8e1864d9c64 322 PIRSF PIRSF017082 2 322 3.9E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01170 196aec2902bfff8aec63e8e1864d9c64 322 SUPERFAMILY SSF53850 107 280 3.36E-13 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Gene3D G3DSA:1.10.40.30 380 444 6.9E-18 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 1.5E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 1.5E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 1.5E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 1.5E-21 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 SUPERFAMILY SSF48557 33 465 4.87E-101 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 2.0E-36 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 2.0E-36 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 2.0E-36 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 2.0E-36 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 2.0E-36 T 06-07-2017 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Pfam PF00206 Lyase 56 304 3.3E-42 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Pfam PF14698 Argininosuccinate lyase C-terminal 368 445 6.2E-18 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 467 30.862 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 TIGRFAM TIGR00838 argH: argininosuccinate lyase 40 468 1.3E-111 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Gene3D G3DSA:1.10.275.10 41 110 1.6E-8 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS04160 4e611615de222ad8387d1ab10b58a18f 510 Gene3D G3DSA:1.20.200.10 111 379 5.3E-72 T 06-07-2017 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 Gene3D G3DSA:3.40.720.10 3 357 5.0E-57 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 Gene3D G3DSA:3.30.1120.10 383 396 9.0E-4 T 06-07-2017 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 Gene3D G3DSA:3.30.1120.10 459 499 9.0E-4 T 06-07-2017 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 Pfam PF00884 Sulfatase 3 338 3.6E-34 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 SUPERFAMILY SSF53649 457 495 1.6E-71 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS10315 1c713ca4b87c75fd8a719f44b9fb8e97 513 SUPERFAMILY SSF53649 3 396 1.6E-71 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 SMART SM00267 51 223 1.4E-62 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 Pfam PF00990 Diguanylate cyclase, GGDEF domain 62 218 3.4E-47 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 SUPERFAMILY SSF55073 67 225 3.22E-49 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 58 221 4.5E-46 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 Gene3D G3DSA:3.20.20.450 237 486 2.2E-94 T 06-07-2017 IPR001633 EAL domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 Pfam PF00563 EAL domain 241 475 1.6E-74 T 06-07-2017 IPR001633 EAL domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 Gene3D G3DSA:3.30.70.270 64 230 5.3E-58 T 06-07-2017 CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 SUPERFAMILY SSF141868 239 487 3.66E-86 T 06-07-2017 IPR001633 EAL domain CAL12_RS26800 59b2c991f5cd7d6fc537cf307889ba24 505 SMART SM00052 232 480 2.0E-104 T 06-07-2017 IPR001633 EAL domain CAL12_RS21130 2774758e0267a193b4e687041ad2cf98 335 PIRSF PIRSF029792 1 335 2.0E-111 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS21130 2774758e0267a193b4e687041ad2cf98 335 Pfam PF05544 Proline racemase 10 332 6.3E-107 T 06-07-2017 IPR008794 Proline racemase family CAL12_RS21130 2774758e0267a193b4e687041ad2cf98 335 SUPERFAMILY SSF54506 1 332 2.92E-102 T 06-07-2017 CAL12_RS21130 2774758e0267a193b4e687041ad2cf98 335 Gene3D G3DSA:3.10.310.10 1 155 1.3E-63 T 06-07-2017 CAL12_RS21130 2774758e0267a193b4e687041ad2cf98 335 Gene3D G3DSA:3.10.310.10 156 322 3.6E-59 T 06-07-2017 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 Gene3D G3DSA:3.30.465.10 101 221 1.0E-33 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 Pfam PF01565 FAD binding domain 44 182 8.3E-35 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 Gene3D G3DSA:3.30.43.10 3 98 3.6E-25 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 SUPERFAMILY SSF56176 6 221 5.95E-70 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 Gene3D G3DSA:1.10.45.10 433 472 1.3E-11 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 SUPERFAMILY SSF55103 224 475 4.41E-57 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS14830 f9c1ddbeb5df72783e5d0a4ce3df1540 479 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 472 6.1E-51 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS24000 ef56bac379bdd31d9ef1399d58f3b3ae 208 Pfam PF01810 LysE type translocator 24 196 3.8E-17 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 PRINTS PR00682 Isopenicillin N synthase signature 209 230 1.7E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 PRINTS PR00682 Isopenicillin N synthase signature 273 291 1.7E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 PRINTS PR00682 Isopenicillin N synthase signature 37 54 1.7E-10 T 06-07-2017 IPR002283 Isopenicillin N synthase GO:0005506|GO:0016491|GO:0055114 CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 Gene3D G3DSA:2.60.120.330 11 304 4.5E-92 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 184 285 3.1E-24 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 14 138 9.9E-27 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAL12_RS23515 775a65edbea19fb0d3906a17f1b44e10 339 SUPERFAMILY SSF51197 13 304 3.43E-88 T 06-07-2017 CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 06-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 242 2.9E-36 T 06-07-2017 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 Gene3D G3DSA:3.40.30.10 172 240 1.3E-20 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 Pfam PF08534 Redoxin 6 160 5.2E-34 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 Gene3D G3DSA:3.40.30.10 3 163 1.1E-65 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 PRINTS PR00160 Glutaredoxin signature 173 191 9.3E-12 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 PRINTS PR00160 Glutaredoxin signature 228 241 9.3E-12 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 PRINTS PR00160 Glutaredoxin signature 214 227 9.3E-12 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 Pfam PF00462 Glutaredoxin 173 231 4.4E-14 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAL12_RS11690 7dd85a76a46f5316756e324f8abbae3f 242 SUPERFAMILY SSF52833 5 239 1.18E-43 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 SUPERFAMILY SSF51905 321 378 7.77E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 SUPERFAMILY SSF51905 5 238 7.77E-37 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 SUPERFAMILY SSF54373 238 321 3.92E-13 T 06-07-2017 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 Gene3D G3DSA:3.50.50.60 149 237 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 Gene3D G3DSA:3.50.50.60 321 377 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 Gene3D G3DSA:3.50.50.60 1 84 3.0E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15060 8caa6f0d509761f0362e63e754e6eea7 382 Pfam PF01266 FAD dependent oxidoreductase 6 348 7.0E-44 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS23975 bce5d8612cb51651f4a612ba6ab6b0d6 555 Pfam PF07690 Major Facilitator Superfamily 40 441 1.7E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23975 bce5d8612cb51651f4a612ba6ab6b0d6 555 SUPERFAMILY SSF103473 25 490 1.96E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23975 bce5d8612cb51651f4a612ba6ab6b0d6 555 Gene3D G3DSA:1.20.1250.20 30 244 2.6E-13 T 06-07-2017 CAL12_RS23975 bce5d8612cb51651f4a612ba6ab6b0d6 555 Gene3D G3DSA:1.20.1250.20 276 492 1.6E-16 T 06-07-2017 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 296 925 3.1E-200 T 06-07-2017 IPR014143 DNA ligase D CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Gene3D G3DSA:2.40.50.140 471 588 2.5E-43 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Pfam PF04679 ATP dependent DNA ligase C terminal region 487 580 8.2E-25 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Pfam PF01068 ATP dependent DNA ligase domain 299 468 1.1E-22 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 656 896 8.6E-81 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Gene3D G3DSA:3.30.1490.70 426 469 2.1E-19 T 06-07-2017 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Gene3D G3DSA:3.30.1490.70 280 309 2.1E-19 T 06-07-2017 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Pfam PF13298 DNA polymerase Ligase (LigD) 36 140 9.0E-38 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 SUPERFAMILY SSF56091 281 468 3.6E-46 T 06-07-2017 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 286 586 6.7E-106 T 06-07-2017 IPR014146 DNA ligase D, ligase domain CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 5 161 1.3E-67 T 06-07-2017 IPR014144 DNA ligase D, 3'-phosphoesterase domain CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 Gene3D G3DSA:3.30.470.30 310 416 6.0E-28 T 06-07-2017 CAL12_RS07230 ccb00f65014efbf6d4a7fe0a773ae280 942 SUPERFAMILY SSF50249 471 591 7.71E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS11800 b519dec4f2af8255245002b80c805c9f 107 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 12 99 7.0E-42 T 06-07-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CAL12_RS11800 b519dec4f2af8255245002b80c805c9f 107 Pfam PF05247 Flagellar transcriptional activator (FlhD) 6 104 2.7E-41 T 06-07-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CAL12_RS11800 b519dec4f2af8255245002b80c805c9f 107 SUPERFAMILY SSF63592 5 99 6.93E-35 T 06-07-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CAL12_RS11800 b519dec4f2af8255245002b80c805c9f 107 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 3 106 27.569 T 06-07-2017 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 SUPERFAMILY SSF53850 92 285 6.65E-25 T 06-07-2017 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 Gene3D G3DSA:3.40.190.10 89 192 2.5E-18 T 06-07-2017 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 Gene3D G3DSA:3.40.190.10 193 236 9.2E-6 T 06-07-2017 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 Gene3D G3DSA:1.10.10.10 6 88 2.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 SUPERFAMILY SSF46785 6 114 1.23E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 Pfam PF03466 LysR substrate binding domain 91 284 2.1E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06675 f8b547f2bc433f5b31a29193c8e2c0e8 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10295 2d801b3729206bd85c1731476753a1d1 446 Gene3D G3DSA:1.20.1250.20 229 432 6.4E-12 T 06-07-2017 CAL12_RS10295 2d801b3729206bd85c1731476753a1d1 446 SUPERFAMILY SSF103473 9 426 7.32E-51 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10295 2d801b3729206bd85c1731476753a1d1 446 Gene3D G3DSA:1.20.1250.20 12 207 1.7E-28 T 06-07-2017 CAL12_RS10295 2d801b3729206bd85c1731476753a1d1 446 Pfam PF07690 Major Facilitator Superfamily 16 384 1.9E-32 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Pfam PF06165 Glycosyltransferase family 36 2058 2298 5.6E-80 T 06-07-2017 IPR010383 Glycosyl hydrolase 94 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Pfam PF06165 Glycosyltransferase family 36 1552 1799 1.3E-64 T 06-07-2017 IPR010383 Glycosyl hydrolase 94 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Gene3D G3DSA:2.60.420.10 2745 2821 3.5E-9 T 06-07-2017 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 SUPERFAMILY SSF48208 2317 2829 7.29E-94 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 SUPERFAMILY SSF74650 1542 1802 2.82E-68 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Pfam PF10091 Putative glucoamylase 1292 1499 5.3E-10 T 06-07-2017 IPR019282 Domain of unknown function DUF2329 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Gene3D G3DSA:2.70.98.40 2035 2357 2.5E-94 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Gene3D G3DSA:2.70.98.40 1549 1835 5.0E-80 T 06-07-2017 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 SMART SM01068 1532 1589 2.7E-18 T 06-07-2017 IPR009342 Putative carbohydrate binding domain CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 SMART SM01068 2035 2100 1.5E-35 T 06-07-2017 IPR009342 Putative carbohydrate binding domain CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 SUPERFAMILY SSF74650 2035 2300 5.34E-91 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS20420 adde2d664af47a9565b8054c1a421f3d 2830 Pfam PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain 2329 2753 1.4E-115 T 06-07-2017 IPR033432 Glycosyl hydrolase 36, catalytic domain CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 Gene3D G3DSA:2.40.160.10 22 387 1.6E-87 T 06-07-2017 IPR023614 Porin domain CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 Pfam PF13609 Gram-negative porin 7 367 4.6E-57 T 06-07-2017 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00184 Neisseria sp. porin signature 341 365 3.0E-9 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00184 Neisseria sp. porin signature 158 175 3.0E-9 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00184 Neisseria sp. porin signature 58 83 3.0E-9 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 56 67 1.1E-5 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 100 110 1.1E-5 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 159 170 1.1E-5 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 344 361 1.1E-5 T 06-07-2017 IPR001702 Porin, Gram-negative type GO:0006810|GO:0015288|GO:0016020 CAL12_RS19715 daf46988fb4ae358adfa79688056b492 387 SUPERFAMILY SSF56935 21 387 1.47E-75 T 06-07-2017 CAL12_RS17005 211678b3dcc5f616557d5c92a37b06ae 151 Pfam PF02627 Carboxymuconolactone decarboxylase family 16 94 9.9E-16 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS17005 211678b3dcc5f616557d5c92a37b06ae 151 SUPERFAMILY SSF69118 5 146 2.49E-42 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS17005 211678b3dcc5f616557d5c92a37b06ae 151 Gene3D G3DSA:1.20.1290.10 2 147 1.7E-49 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS17005 211678b3dcc5f616557d5c92a37b06ae 151 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 28 76 1.6E-15 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS16765 b4a895d31119847ef2c2a49fd9b62140 542 Gene3D G3DSA:1.10.287.950 302 506 5.6E-56 T 06-07-2017 CAL12_RS16765 b4a895d31119847ef2c2a49fd9b62140 542 SMART SM00283 287 534 5.5E-83 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS16765 b4a895d31119847ef2c2a49fd9b62140 542 Pfam PF12729 Four helix bundle sensory module for signal transduction 34 200 2.5E-7 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS16765 b4a895d31119847ef2c2a49fd9b62140 542 SUPERFAMILY SSF58104 255 538 4.97E-68 T 06-07-2017 CAL12_RS16765 b4a895d31119847ef2c2a49fd9b62140 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 533 1.4E-54 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS14510 464b6d26cc9bc58975466dec848be5ce 114 SUPERFAMILY SSF47413 13 63 9.78E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS14510 464b6d26cc9bc58975466dec848be5ce 114 Gene3D G3DSA:1.10.260.40 11 64 2.2E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS14510 464b6d26cc9bc58975466dec848be5ce 114 Pfam PF13560 Helix-turn-helix domain 17 68 7.1E-7 T 06-07-2017 CAL12_RS25710 3ded7480924e010ed38ae354195d44b5 305 SUPERFAMILY SSF161098 99 294 2.35E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25710 3ded7480924e010ed38ae354195d44b5 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 304 5.3E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25710 3ded7480924e010ed38ae354195d44b5 305 Gene3D G3DSA:1.10.3720.10 95 303 7.5E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18525 45282684503bdca105c2b61b273506b0 442 SUPERFAMILY SSF103473 18 437 1.7E-82 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS18525 45282684503bdca105c2b61b273506b0 442 Pfam PF07690 Major Facilitator Superfamily 37 398 3.4E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS18525 45282684503bdca105c2b61b273506b0 442 Gene3D G3DSA:1.20.1250.20 28 228 3.2E-47 T 06-07-2017 CAL12_RS18525 45282684503bdca105c2b61b273506b0 442 Gene3D G3DSA:1.20.1250.20 254 437 5.3E-22 T 06-07-2017 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 Gene3D G3DSA:1.10.357.10 60 183 2.6E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 Gene3D G3DSA:1.10.10.60 5 59 3.4E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 SUPERFAMILY SSF48498 78 178 3.63E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 SUPERFAMILY SSF46689 4 73 7.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16820 e146794115804fc00641e03e74ed3ed9 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.8E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 8.8E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 8.8E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 SUPERFAMILY SSF46785 17 90 1.55E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 SUPERFAMILY SSF64288 74 253 2.36E-38 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 86 4.5E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 SMART SM00866 106 246 5.2E-24 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 SMART SM00345 27 86 2.3E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 Gene3D G3DSA:1.10.10.10 18 83 5.6E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 Gene3D G3DSA:3.40.1410.10 84 253 3.5E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS13740 1e64f9722d429a42a03d4c9c1abfa73a 263 Pfam PF07702 UTRA domain 112 245 5.8E-30 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS23385 45a81924c07870fbd4bf3f8d0a352d38 322 Pfam PF01522 Polysaccharide deacetylase 86 195 1.6E-13 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS23385 45a81924c07870fbd4bf3f8d0a352d38 322 SUPERFAMILY SSF88713 40 309 5.78E-53 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS23385 45a81924c07870fbd4bf3f8d0a352d38 322 Gene3D G3DSA:3.20.20.370 40 310 1.7E-58 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 24 214 4.2E-82 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 Pfam PF00925 GTP cyclohydrolase II 224 381 4.8E-32 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 Gene3D G3DSA:3.90.870.10 13 225 4.5E-98 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 PIRSF PIRSF001259 18 386 3.0E-115 T 06-07-2017 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 SUPERFAMILY SSF142695 221 382 3.66E-41 T 06-07-2017 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 17 219 38.377 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 20 215 1.6E-72 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS02960 53f313dabbefc33db052892dc3e54386 392 SUPERFAMILY SSF55821 17 219 3.2E-85 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS08835 041d44e19073a5aced0db0d69078ef1a 324 SUPERFAMILY SSF53850 88 279 1.26E-9 T 06-07-2017 CAL12_RS08835 041d44e19073a5aced0db0d69078ef1a 324 PIRSF PIRSF017082 1 324 3.7E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08835 041d44e19073a5aced0db0d69078ef1a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 1.3E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 334 350 2.1E-27 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 388 405 2.1E-27 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 215 225 2.1E-27 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 284 296 2.1E-27 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 186 200 2.1E-27 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 Gene3D G3DSA:3.30.70.1170 134 194 5.4E-14 T 06-07-2017 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 Pfam PF01189 16S rRNA methyltransferase RsmB/F 204 403 1.2E-45 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 SUPERFAMILY SSF53335 99 405 1.53E-66 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17280 b7a055014d25311c0ad4df4a163b8cf6 464 Gene3D G3DSA:3.40.50.150 196 405 9.1E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26135 4eb8135e082172506488e6221ff31f70 645 Gene3D G3DSA:1.50.10.10 219 615 2.0E-85 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAL12_RS26135 4eb8135e082172506488e6221ff31f70 645 Pfam PF00723 Glycosyl hydrolases family 15 221 583 4.1E-62 T 06-07-2017 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CAL12_RS26135 4eb8135e082172506488e6221ff31f70 645 SUPERFAMILY SSF48208 196 590 4.54E-110 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 Pfam PF14815 NUDIX domain 237 343 2.8E-24 T 06-07-2017 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 3 267 1.2E-102 T 06-07-2017 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 164 1.6E-21 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 SUPERFAMILY SSF48150 3 224 3.45E-68 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 SUPERFAMILY SSF55811 222 345 3.63E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 Gene3D G3DSA:1.10.1670.10 121 224 4.8E-35 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 SMART SM00478 36 192 8.3E-42 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 Gene3D G3DSA:3.90.79.10 231 345 2.6E-26 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 ProSitePatterns PS01155 Endonuclease III family signature. 99 128 - T 06-07-2017 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 194 210 - T 06-07-2017 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAL12_RS25280 15c295b178079fbedc68a97997408d69 357 Gene3D G3DSA:1.10.340.30 18 120 1.2E-43 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS21845 f42db9fb8088b5db00d6d7c525f1ab6d 198 Gene3D G3DSA:1.10.10.60 1 64 4.9E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21845 f42db9fb8088b5db00d6d7c525f1ab6d 198 SUPERFAMILY SSF46689 1 70 6.67E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21845 f42db9fb8088b5db00d6d7c525f1ab6d 198 Gene3D G3DSA:1.10.357.10 75 192 4.7E-24 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS21845 f42db9fb8088b5db00d6d7c525f1ab6d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.1E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS21845 f42db9fb8088b5db00d6d7c525f1ab6d 198 SUPERFAMILY SSF48498 79 191 1.68E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SMART SM00982 1017 1117 7.9E-48 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 162 1090 0.0 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SMART SM00490 835 919 1.8E-16 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF141259 480 557 6.67E-23 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Gene3D G3DSA:3.40.50.300 602 795 4.4E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF52540 24 354 3.61E-94 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 44 1119 28.189 T 06-07-2017 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Gene3D G3DSA:3.30.2060.10 144 217 4.1E-11 T 06-07-2017 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF143517 1003 1153 3.01E-39 T 06-07-2017 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Pfam PF03461 TRCF domain 1018 1110 1.7E-26 T 06-07-2017 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF52540 360 471 1.01E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SMART SM00487 609 799 2.3E-32 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Pfam PF00271 Helicase conserved C-terminal domain 813 918 3.0E-17 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF52540 792 999 3.55E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Gene3D G3DSA:3.40.50.300 809 965 2.7E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Pfam PF00270 DEAD/DEAH box helicase 615 771 3.2E-17 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 Pfam PF02559 CarD-like/TRCF domain 489 584 3.4E-26 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SUPERFAMILY SSF52540 532 792 3.78E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19615 b1cf988603341e933186711ca1f6a3dc 1154 SMART SM01058 488 585 8.2E-47 T 06-07-2017 IPR003711 CarD-like/TRCF domain CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 Pfam PF02152 Dihydroneopterin aldolase 8 115 1.6E-28 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 TIGRFAM TIGR00526 folB_dom: FolB domain 8 116 2.0E-19 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 SMART SM00905 6 117 2.2E-30 T 06-07-2017 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 Gene3D G3DSA:3.30.1130.10 4 118 1.2E-32 T 06-07-2017 CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 6 115 7.8E-25 T 06-07-2017 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CAL12_RS25860 90fef9bbe7d962a179bac0c4508662cc 119 SUPERFAMILY SSF55620 3 119 3.17E-29 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 Pfam PF01494 FAD binding domain 4 342 1.5E-85 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 SUPERFAMILY SSF51905 3 173 3.65E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 SUPERFAMILY SSF51905 263 376 3.65E-60 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 Gene3D G3DSA:3.50.50.60 2 163 8.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 Gene3D G3DSA:3.50.50.60 274 312 8.2E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 343 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 327 1.6E-44 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 Gene3D G3DSA:3.30.9.10 164 269 1.2E-15 T 06-07-2017 CAL12_RS04735 8b468e63ceb7bf5b7f079931238ab2e9 503 Gene3D G3DSA:3.30.9.10 324 348 1.2E-15 T 06-07-2017 CAL12_RS10275 dd1817f3dbdd4beec498065133b641a0 147 Gene3D G3DSA:1.20.1290.10 18 138 8.1E-15 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS10275 dd1817f3dbdd4beec498065133b641a0 147 SUPERFAMILY SSF69118 21 137 1.1E-12 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS10275 dd1817f3dbdd4beec498065133b641a0 147 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 131 3.6E-5 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 TIGRFAM TIGR01404 FlhB_rel_III: type III secretion protein, YscU/HrpY family 7 347 1.6E-108 T 06-07-2017 IPR006307 Type III exporter system, secretion apparatus protein BsaZ GO:0009306|GO:0016021 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 Pfam PF01312 FlhB HrpN YscU SpaS Family 7 345 2.3E-100 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 226 243 3.0E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 300 321 3.0E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.0E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 270 285 3.0E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 206 224 3.0E-36 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 Gene3D G3DSA:3.40.1690.10 216 350 2.8E-47 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS22040 557f376367b2ee363c0cab00a1191379 360 SUPERFAMILY SSF160544 242 348 9.29E-31 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS00035 6fc30c6939d916e35b395e97e7a09270 234 Pfam PF02678 Pirin 45 118 3.0E-18 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAL12_RS00035 6fc30c6939d916e35b395e97e7a09270 234 Gene3D G3DSA:2.60.120.10 31 233 7.7E-39 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS00035 6fc30c6939d916e35b395e97e7a09270 234 SUPERFAMILY SSF51182 24 233 3.04E-43 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 Pfam PF03466 LysR substrate binding domain 128 330 1.4E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 58 69 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 69 79 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 79 90 1.3E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 Gene3D G3DSA:3.40.190.10 129 220 6.0E-16 T 06-07-2017 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 Gene3D G3DSA:3.40.190.10 221 300 9.5E-21 T 06-07-2017 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 SUPERFAMILY SSF53850 130 335 9.93E-35 T 06-07-2017 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 SUPERFAMILY SSF46785 39 120 3.89E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 43 101 2.6E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21105 c2bffe53ace79341eda7850383440607 345 Gene3D G3DSA:1.10.10.10 41 127 1.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20130 99db845f8b764ac54bdf9cbaad05206c 704 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 14 191 2.6E-58 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS20130 99db845f8b764ac54bdf9cbaad05206c 704 Pfam PF01968 Hydantoinase/oxoprolinase 212 506 4.0E-89 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 505 7.9E-21 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 8 513 4.0E-235 T 06-07-2017 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Gene3D G3DSA:3.40.50.980 178 333 1.2E-37 T 06-07-2017 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 SUPERFAMILY SSF56801 9 516 3.27E-149 T 06-07-2017 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Gene3D G3DSA:2.30.38.10 338 412 3.7E-20 T 06-07-2017 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Gene3D G3DSA:3.40.50.980 11 177 2.0E-33 T 06-07-2017 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Pfam PF00501 AMP-binding enzyme 17 419 9.1E-97 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS05275 6ce2c3441571376aaab600fe5f8d0869 518 Gene3D G3DSA:3.30.300.30 413 515 1.4E-31 T 06-07-2017 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 SUPERFAMILY SSF54919 6 143 1.57E-56 T 06-07-2017 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 118 126 - T 06-07-2017 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 Pfam PF00334 Nucleoside diphosphate kinase 8 140 1.2E-54 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 Gene3D G3DSA:3.30.70.141 6 142 8.8E-58 T 06-07-2017 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 118 137 8.0E-40 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 54 73 8.0E-40 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 74 91 8.0E-40 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 95 111 8.0E-40 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 PRINTS PR01243 Nucleoside diphosphate kinase signature 10 32 8.0E-40 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 7 142 35.176 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS09205 6414edc41a51ecd1c01ca02233f6949f 145 SMART SM00562 7 144 1.4E-84 T 06-07-2017 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CAL12_RS24180 55807e7c470d23036b0ff6da37a41fb5 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 1.9E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24180 55807e7c470d23036b0ff6da37a41fb5 327 PIRSF PIRSF017082 2 326 6.0E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24180 55807e7c470d23036b0ff6da37a41fb5 327 SUPERFAMILY SSF53850 54 287 6.73E-14 T 06-07-2017 CAL12_RS01265 00c9adfba57ccff9149fa0a3d1498237 170 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 157 1.4E-49 T 06-07-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CAL12_RS01265 00c9adfba57ccff9149fa0a3d1498237 170 Pfam PF00694 Aconitase C-terminal domain 52 105 2.6E-16 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01265 00c9adfba57ccff9149fa0a3d1498237 170 Gene3D G3DSA:3.20.19.10 7 158 4.0E-27 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS01265 00c9adfba57ccff9149fa0a3d1498237 170 SUPERFAMILY SSF52016 3 158 5.3E-41 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 Gene3D G3DSA:3.10.350.10 146 191 1.1E-16 T 06-07-2017 IPR018392 LysM domain CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 SUPERFAMILY SSF51261 148 352 1.46E-40 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 Gene3D G3DSA:2.70.70.10 219 353 4.4E-35 T 06-07-2017 CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 Pfam PF01476 LysM domain 148 190 1.8E-11 T 06-07-2017 IPR018392 LysM domain CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 SMART SM00257 147 191 3.5E-12 T 06-07-2017 IPR018392 LysM domain CAL12_RS08940 ae1979033e9afd34ba9dd0802e1b7f97 355 Pfam PF01551 Peptidase family M23 255 348 3.5E-29 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Pfam PF00226 DnaJ domain 5 67 5.7E-28 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Gene3D G3DSA:2.10.230.10 138 199 1.9E-23 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SUPERFAMILY SSF46565 1 109 2.62E-36 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SUPERFAMILY SSF57938 134 211 8.37E-22 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Gene3D G3DSA:2.60.260.20 200 254 5.9E-22 T 06-07-2017 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Gene3D G3DSA:2.60.260.20 116 137 5.9E-22 T 06-07-2017 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Gene3D G3DSA:2.60.260.20 256 333 4.0E-24 T 06-07-2017 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 349 5.1E-137 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Gene3D G3DSA:1.10.287.110 1 102 1.8E-37 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Pfam PF00684 DnaJ central domain 147 207 1.2E-13 T 06-07-2017 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SUPERFAMILY SSF49493 259 344 8.11E-24 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 06-07-2017 IPR018253 DnaJ domain, conserved site CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SUPERFAMILY SSF49493 115 138 6.15E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SUPERFAMILY SSF49493 186 259 6.15E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 PRINTS PR00625 DnaJ domain signature 7 25 1.7E-33 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 PRINTS PR00625 DnaJ domain signature 25 40 1.7E-33 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 PRINTS PR00625 DnaJ domain signature 42 62 1.7E-33 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 PRINTS PR00625 DnaJ domain signature 62 81 1.7E-33 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 372 41.769 T 06-07-2017 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 SMART SM00271 4 62 1.9E-30 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS06245 087635f814b16d4b617c938e327abf64 374 Pfam PF01556 DnaJ C terminal domain 121 333 4.3E-42 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAL12_RS01115 e903b3735d7dcb3823830e6d7682dfea 215 SUPERFAMILY SSF52499 17 212 2.49E-51 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS01115 e903b3735d7dcb3823830e6d7682dfea 215 Pfam PF00857 Isochorismatase family 34 208 1.7E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS01115 e903b3735d7dcb3823830e6d7682dfea 215 Gene3D G3DSA:3.40.50.850 35 212 1.2E-50 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 Pfam PF05954 Phage late control gene D protein (GPD) 49 359 1.5E-72 T 06-07-2017 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 SUPERFAMILY SSF69255 401 488 4.45E-24 T 06-07-2017 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 44 540 7.3E-98 T 06-07-2017 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 40 557 4.1E-116 T 06-07-2017 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 SUPERFAMILY SSF69279 215 394 4.08E-20 T 06-07-2017 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 SUPERFAMILY SSF69279 32 210 1.3E-39 T 06-07-2017 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 SUPERFAMILY SSF69349 478 657 8.63E-19 T 06-07-2017 CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 Gene3D G3DSA:2.40.50.230 403 487 4.1E-30 T 06-07-2017 IPR006531 Gp5 N-terminal CAL12_RS22690 b44e6632902c065c46e95be4abce76b1 683 Gene3D G3DSA:3.55.50.10 123 214 1.2E-29 T 06-07-2017 CAL12_RS03260 61c9dde88f1ad85ca8e5158cbb47b617 283 SUPERFAMILY SSF161098 12 283 3.92E-64 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03260 61c9dde88f1ad85ca8e5158cbb47b617 283 Gene3D G3DSA:1.10.3720.10 12 270 7.6E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03260 61c9dde88f1ad85ca8e5158cbb47b617 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 276 6.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19545 95bd5f9ab339b4936ac4b26c2ad877e2 88 PIRSF PIRSF003113 1 88 1.7E-25 T 06-07-2017 IPR002634 BolA protein CAL12_RS19545 95bd5f9ab339b4936ac4b26c2ad877e2 88 Pfam PF01722 BolA-like protein 16 88 3.3E-27 T 06-07-2017 IPR002634 BolA protein CAL12_RS19545 95bd5f9ab339b4936ac4b26c2ad877e2 88 Gene3D G3DSA:3.30.70.1500 8 87 3.7E-25 T 06-07-2017 CAL12_RS19545 95bd5f9ab339b4936ac4b26c2ad877e2 88 SUPERFAMILY SSF82657 5 88 4.32E-23 T 06-07-2017 IPR002634 BolA protein CAL12_RS15910 326c3b7ae116c0bdda1f9dfe869fc020 292 SUPERFAMILY SSF161098 85 272 1.26E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15910 326c3b7ae116c0bdda1f9dfe869fc020 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 4.8E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15910 326c3b7ae116c0bdda1f9dfe869fc020 292 Gene3D G3DSA:1.10.3720.10 84 288 5.3E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15910 326c3b7ae116c0bdda1f9dfe869fc020 292 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 67 1.9E-13 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 Gene3D G3DSA:3.40.50.720 11 267 4.6E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 7.7E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.7E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 7.7E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.7E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.7E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 SUPERFAMILY SSF51735 5 264 1.33E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 Pfam PF00106 short chain dehydrogenase 11 198 1.9E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19910 18455bf69821e5bfa25d03167786ec86 312 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 Pfam PF01019 Gamma-glutamyltranspeptidase 39 530 2.1E-149 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 SUPERFAMILY SSF56235 10 535 1.0E-167 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 229 245 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 46 71 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 377 395 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 432 449 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 423 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS01500 c3948c9a46012a713c79b6afed325e69 535 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 353 371 2.8E-38 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS10630 4d4832bc130ebb16770c7330d0634e83 309 SUPERFAMILY SSF53850 99 269 1.72E-12 T 06-07-2017 CAL12_RS10630 4d4832bc130ebb16770c7330d0634e83 309 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 32 303 3.9E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10630 4d4832bc130ebb16770c7330d0634e83 309 PIRSF PIRSF017082 1 308 1.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 Gene3D G3DSA:3.40.30.10 1 91 7.9E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 111 188 2.6E-9 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 8.3E-17 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 SUPERFAMILY SSF52833 1 101 9.42E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 SUPERFAMILY SSF47616 80 200 1.53E-24 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS00745 ce65353ce45a22355b3d6efbf6b586ca 203 Gene3D G3DSA:1.20.1050.10 92 199 2.8E-20 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Pfam PF13177 DNA polymerase III, delta subunit 20 178 1.4E-37 T 06-07-2017 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 701 814 5.8E-6 T 06-07-2017 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Gene3D G3DSA:1.10.8.60 167 242 5.7E-31 T 06-07-2017 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Gene3D G3DSA:1.20.272.10 243 358 3.1E-30 T 06-07-2017 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Gene3D G3DSA:3.40.50.300 2 166 6.3E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 SMART SM00382 37 179 7.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 359 2.1E-19 T 06-07-2017 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 SUPERFAMILY SSF52540 34 224 2.94E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 SUPERFAMILY SSF48019 243 358 2.04E-22 T 06-07-2017 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CAL12_RS06465 28dd18ae199810e770167436c9ac35bd 830 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 4.1E-122 T 06-07-2017 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 272 283 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Gene3D G3DSA:2.60.40.10 337 459 1.2E-21 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Pfam PF13746 4Fe-4S dicluster domain 196 301 1.7E-39 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 248 259 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Gene3D G3DSA:3.30.70.20 257 289 3.1E-4 T 06-07-2017 CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 337 458 6.0E-20 T 06-07-2017 IPR032879 FixG, C-terminal immunoglobulin-like domain CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Pfam PF12801 4Fe-4S binding domain 71 113 6.7E-13 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 17 419 6.7E-141 T 06-07-2017 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 Gene3D G3DSA:3.30.70.20 199 256 9.5E-7 T 06-07-2017 CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 SUPERFAMILY SSF54862 81 103 2.68E-32 T 06-07-2017 CAL12_RS14350 3ba01735f561200ff3225a899df618db 459 SUPERFAMILY SSF54862 149 333 2.68E-32 T 06-07-2017 CAL12_RS05110 d9cec3ebfda51a771b79b02254f28b2d 294 SUPERFAMILY SSF51197 3 279 6.87E-79 T 06-07-2017 CAL12_RS05110 d9cec3ebfda51a771b79b02254f28b2d 294 Gene3D G3DSA:3.60.130.10 3 281 1.3E-81 T 06-07-2017 CAL12_RS05110 d9cec3ebfda51a771b79b02254f28b2d 294 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 6 276 2.4E-63 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 SUPERFAMILY SSF55781 79 264 3.07E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 Gene3D G3DSA:3.30.450.40 99 264 9.7E-33 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 Pfam PF09339 IclR helix-turn-helix domain 23 73 2.1E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 SUPERFAMILY SSF46785 21 94 5.27E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 Gene3D G3DSA:1.10.10.10 12 82 5.9E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 Pfam PF01614 Bacterial transcriptional regulator 141 259 3.0E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS05920 9ce8186b3046aceec74473b88877cd77 269 SMART SM00346 20 110 5.5E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 SUPERFAMILY SSF47384 198 269 1.24E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.1E-7 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 SMART SM00387 318 423 5.6E-21 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 SUPERFAMILY SSF55874 281 423 3.93E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 422 1.1E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS21300 9b9547a4e2a9940132f67aca9d9c2840 436 Gene3D G3DSA:3.30.565.10 284 422 3.8E-25 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 PRINTS PR00046 Major sigma-70 factor signature 540 553 7.6E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 PRINTS PR00046 Major sigma-70 factor signature 709 724 7.6E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 PRINTS PR00046 Major sigma-70 factor signature 724 735 7.6E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 PRINTS PR00046 Major sigma-70 factor signature 688 700 7.6E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 PRINTS PR00046 Major sigma-70 factor signature 564 572 7.6E-31 T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF04546 Sigma-70, non-essential region 285 485 1.3E-63 T 06-07-2017 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 512 748 2.6E-118 T 06-07-2017 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF04545 Sigma-70, region 4 684 737 6.5E-19 T 06-07-2017 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF03979 Sigma-70 factor, region 1.1 148 227 9.5E-29 T 06-07-2017 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 SUPERFAMILY SSF88659 589 662 2.04E-18 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 SUPERFAMILY SSF88946 261 583 4.24E-97 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 148 749 42.073 T 06-07-2017 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 SUPERFAMILY SSF88659 646 747 1.12E-26 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 512 737 3.3E-39 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Gene3D G3DSA:1.10.601.10 258 585 1.9E-124 T 06-07-2017 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Gene3D G3DSA:1.10.10.10 589 640 5.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF04542 Sigma-70 region 2 518 585 8.4E-21 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF00140 Sigma-70 factor, region 1.2 244 276 3.7E-14 T 06-07-2017 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 709 735 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 540 553 - T 06-07-2017 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Pfam PF04539 Sigma-70 region 3 595 670 4.4E-24 T 06-07-2017 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS09295 950c2fcd19b699f556bb4451a09a6fc6 751 Gene3D G3DSA:1.10.10.10 679 749 3.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08460 683c2282660f9df3eed493c5e6f2eaba 379 Pfam PF03739 Predicted permease YjgP/YjgQ family 8 356 1.7E-53 T 06-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 CAL12_RS08460 683c2282660f9df3eed493c5e6f2eaba 379 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 3 355 3.7E-103 T 06-07-2017 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 Pfam PF07883 Cupin domain 176 243 3.3E-21 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 Pfam PF01381 Helix-turn-helix 70 122 1.4E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 SUPERFAMILY SSF51182 110 247 1.78E-29 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 Gene3D G3DSA:2.60.120.10 150 248 2.0E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 SUPERFAMILY SSF47413 63 130 6.76E-15 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 SMART SM00530 69 124 3.7E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS02400 eedc8af7ad63f1fcc5d6d0ceb92854fd 249 Gene3D G3DSA:1.10.260.40 61 130 3.1E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS07700 f14b4d0cea2e1d89e853f8cb9ca7bca8 184 Gene3D G3DSA:3.40.630.30 14 178 5.9E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS07700 f14b4d0cea2e1d89e853f8cb9ca7bca8 184 SUPERFAMILY SSF55729 9 164 1.46E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS07700 f14b4d0cea2e1d89e853f8cb9ca7bca8 184 Pfam PF00583 Acetyltransferase (GNAT) family 70 155 2.6E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS20930 f6510ca3cbeb63ef40e48017578f8de9 223 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 10 216 6.6E-67 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAL12_RS20930 f6510ca3cbeb63ef40e48017578f8de9 223 Pfam PF02666 Phosphatidylserine decarboxylase 44 210 6.0E-30 T 06-07-2017 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CAL12_RS20930 f6510ca3cbeb63ef40e48017578f8de9 223 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 10 215 37.344 T 06-07-2017 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 SUPERFAMILY SSF56059 301 449 6.6E-10 T 06-07-2017 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 SUPERFAMILY SSF48452 24 144 1.96E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 Gene3D G3DSA:1.25.40.10 29 144 7.6E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 SMART SM00028 95 128 13.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 SMART SM00028 27 60 2.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS15175 7ef225f807b5a426fb2663dbe6282784 489 Gene3D G3DSA:3.30.1490.20 292 328 6.7E-4 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS00565 f748f8e13f5179e09bb7232d73143cb4 214 Pfam PF13462 Thioredoxin 48 189 1.5E-12 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00565 f748f8e13f5179e09bb7232d73143cb4 214 Gene3D G3DSA:3.40.30.10 36 210 2.9E-46 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00565 f748f8e13f5179e09bb7232d73143cb4 214 ProSitePatterns PS00194 Thioredoxin family active site. 53 71 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAL12_RS00565 f748f8e13f5179e09bb7232d73143cb4 214 SUPERFAMILY SSF52833 36 194 1.05E-34 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS00565 f748f8e13f5179e09bb7232d73143cb4 214 PIRSF PIRSF001488 5 214 7.1E-57 T 06-07-2017 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 Pfam PF06628 Catalase-related immune-responsive 422 483 8.1E-14 T 06-07-2017 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 Pfam PF00199 Catalase 13 390 8.8E-182 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 Gene3D G3DSA:2.40.180.10 9 362 4.9E-169 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 338 346 - T 06-07-2017 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 SUPERFAMILY SSF56634 8 487 3.01E-197 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 109 126 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 293 320 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 88 106 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 128 146 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 325 351 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PRINTS PR00067 Catalase signature 26 49 8.7E-69 T 06-07-2017 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 ProSitePatterns PS00438 Catalase proximal active site signature. 49 65 - T 06-07-2017 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 PIRSF PIRSF038928 2 490 6.5E-230 T 06-07-2017 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS19930 83bbc0c2c5ebac7d1da090d33173c0f4 499 SMART SM01060 13 395 1.6E-270 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 313 1.3E-11 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 Gene3D G3DSA:3.40.50.720 121 288 4.2E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 Gene3D G3DSA:3.40.50.720 2 120 2.0E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 SUPERFAMILY SSF51735 108 287 1.78E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 287 2.1E-55 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS26070 ef1faddb5169ca86a882ce527785f0a7 317 SUPERFAMILY SSF52283 2 128 5.53E-24 T 06-07-2017 CAL12_RS14070 242eb0c5b54fca5061938c19ceb14e80 427 Gene3D G3DSA:3.30.1540.10 235 316 4.2E-22 T 06-07-2017 CAL12_RS14070 242eb0c5b54fca5061938c19ceb14e80 427 Gene3D G3DSA:3.40.50.10540 317 407 1.1E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14070 242eb0c5b54fca5061938c19ceb14e80 427 Gene3D G3DSA:3.40.50.10540 12 228 1.1E-96 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14070 242eb0c5b54fca5061938c19ceb14e80 427 SUPERFAMILY SSF89796 12 407 2.62E-115 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14070 242eb0c5b54fca5061938c19ceb14e80 427 Pfam PF02515 CoA-transferase family III 17 384 3.2E-100 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS15970 af677e40bb6fbc7f4807c8a6f6bcfdfa 264 SUPERFAMILY SSF53098 4 226 9.38E-40 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS15970 af677e40bb6fbc7f4807c8a6f6bcfdfa 264 Gene3D G3DSA:3.30.420.10 47 215 8.9E-28 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS15970 af677e40bb6fbc7f4807c8a6f6bcfdfa 264 Gene3D G3DSA:3.30.420.10 5 15 8.9E-28 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS15970 af677e40bb6fbc7f4807c8a6f6bcfdfa 264 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 48 257 4.3E-91 T 06-07-2017 IPR019288 Predicted 3'-5' exonuclease, PolB-like CAL12_RS27195 4aaac32868cc53c00b3d3eda839f3c4b 476 Pfam PF03972 MmgE/PrpD family 29 443 9.2E-84 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27195 4aaac32868cc53c00b3d3eda839f3c4b 476 SUPERFAMILY SSF103378 26 467 3.66E-81 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27195 4aaac32868cc53c00b3d3eda839f3c4b 476 Gene3D G3DSA:3.30.1330.120 289 412 2.9E-15 T 06-07-2017 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 34 49 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 SUPERFAMILY SSF118215 7 401 1.44E-92 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 Pfam PF00375 Sodium:dicarboxylate symporter family 7 400 4.4E-91 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 Gene3D G3DSA:1.10.3860.10 5 405 9.4E-93 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 PRINTS PR00173 Glutamate-aspartate symporter signature 72 97 9.1E-17 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 PRINTS PR00173 Glutamate-aspartate symporter signature 191 210 9.1E-17 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 PRINTS PR00173 Glutamate-aspartate symporter signature 326 345 9.1E-17 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 9.1E-17 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS13720 b2ab7329aacaef93c0376172278b94ad 435 PRINTS PR00173 Glutamate-aspartate symporter signature 291 317 9.1E-17 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS14065 444494c1a0b5e183b4ab21f8733899a4 316 Gene3D G3DSA:3.20.20.70 1 297 3.5E-55 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS14065 444494c1a0b5e183b4ab21f8733899a4 316 SUPERFAMILY SSF51412 1 311 1.83E-59 T 06-07-2017 CAL12_RS14065 444494c1a0b5e183b4ab21f8733899a4 316 Pfam PF03060 Nitronate monooxygenase 3 81 1.0E-16 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAL12_RS14065 444494c1a0b5e183b4ab21f8733899a4 316 Pfam PF03060 Nitronate monooxygenase 85 302 1.6E-42 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 Pfam PF00119 ATP synthase A chain 43 286 8.8E-53 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 35 288 1.1E-40 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 ProSitePatterns PS00449 ATP synthase a subunit signature. 216 225 - T 06-07-2017 IPR023011 ATPase, F0 complex, subunit A, active site Reactome: R-HSA-163210 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 Gene3D G3DSA:1.20.120.220 97 293 1.2E-46 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 SUPERFAMILY SSF81336 97 287 1.7E-35 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAL12_RS25825 5431716d753565df7d1367e12fdd0810 293 Hamap MF_01393 ATP synthase subunit a [atpB]. 14 293 13.911 T 06-07-2017 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 3.9E-121 T 06-07-2017 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 Pfam PF00494 Squalene/phytoene synthase 13 264 1.2E-81 T 06-07-2017 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 Gene3D G3DSA:1.10.600.10 4 277 2.1E-96 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 SUPERFAMILY SSF48576 3 276 2.37E-90 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS18190 1b00ef184d322c53d38295ff16dac5ab 287 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 122 137 - T 06-07-2017 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CAL12_RS25670 25719b7abf42fc74e395622890a02eed 347 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 72 343 6.8E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25670 25719b7abf42fc74e395622890a02eed 347 PIRSF PIRSF017082 19 347 1.5E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25670 25719b7abf42fc74e395622890a02eed 347 SUPERFAMILY SSF53850 141 307 5.64E-14 T 06-07-2017 CAL12_RS25670 25719b7abf42fc74e395622890a02eed 347 Gene3D G3DSA:3.40.190.10 154 253 3.4E-4 T 06-07-2017 CAL12_RS24755 0d1ed9b03aba51ed0d66fa3b625595b5 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24755 0d1ed9b03aba51ed0d66fa3b625595b5 236 Pfam PF00005 ABC transporter 21 164 1.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24755 0d1ed9b03aba51ed0d66fa3b625595b5 236 SMART SM00382 29 230 1.5E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24755 0d1ed9b03aba51ed0d66fa3b625595b5 236 SUPERFAMILY SSF52540 4 234 7.99E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24755 0d1ed9b03aba51ed0d66fa3b625595b5 236 Gene3D G3DSA:3.40.50.300 2 230 7.1E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06255 7fab5dfe35910024b4526fb5520e6d4d 289 Pfam PF01522 Polysaccharide deacetylase 69 174 4.1E-7 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS06255 7fab5dfe35910024b4526fb5520e6d4d 289 SUPERFAMILY SSF88713 5 287 6.45E-62 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS06255 7fab5dfe35910024b4526fb5520e6d4d 289 Gene3D G3DSA:3.20.20.370 5 287 2.7E-57 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS05865 52ee9758931ddeb5f9220d5fab2c2c6f 353 Gene3D G3DSA:3.40.190.10 140 263 1.8E-18 T 06-07-2017 CAL12_RS05865 52ee9758931ddeb5f9220d5fab2c2c6f 353 SUPERFAMILY SSF53850 46 286 4.51E-30 T 06-07-2017 CAL12_RS05865 52ee9758931ddeb5f9220d5fab2c2c6f 353 Pfam PF09084 NMT1/THI5 like 88 273 1.1E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 Gene3D G3DSA:1.10.560.10 4 188 1.0E-48 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 Gene3D G3DSA:3.50.7.10 189 368 9.3E-99 T 06-07-2017 IPR027409 GroEL-like apical domain CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 SUPERFAMILY SSF52029 184 376 4.71E-83 T 06-07-2017 IPR027409 GroEL-like apical domain CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 SUPERFAMILY SSF54849 137 203 6.87E-25 T 06-07-2017 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 SUPERFAMILY SSF48592 406 521 9.92E-76 T 06-07-2017 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 SUPERFAMILY SSF48592 7 134 9.92E-76 T 06-07-2017 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 PRINTS PR00298 60kDa chaperonin signature 350 375 5.5E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 PRINTS PR00298 60kDa chaperonin signature 83 110 5.5E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 PRINTS PR00298 60kDa chaperonin signature 27 53 5.5E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 PRINTS PR00298 60kDa chaperonin signature 268 291 5.5E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 PRINTS PR00298 60kDa chaperonin signature 398 419 5.5E-74 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 06-07-2017 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.579 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 Gene3D G3DSA:1.10.560.10 369 518 6.8E-41 T 06-07-2017 IPR027413 GroEL-like equatorial domain CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 4.3E-255 T 06-07-2017 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 CAL12_RS03100 200337ffa6d4a6ec714e181769759577 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 4.0E-98 T 06-07-2017 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 Gene3D G3DSA:3.40.50.300 13 248 5.6E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 SMART SM00382 38 225 2.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 SUPERFAMILY SSF52540 14 247 3.04E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 PIRSF PIRSF039085 10 253 5.6E-105 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS25935 4b6ce2795e2bcd4ce7df1160b81923fe 253 Pfam PF00005 ABC transporter 29 177 3.5E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03750 9a27b1ebd3621fe1602f2ce9866413f6 429 Pfam PF07690 Major Facilitator Superfamily 18 352 3.6E-14 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS03750 9a27b1ebd3621fe1602f2ce9866413f6 429 SUPERFAMILY SSF103473 16 413 4.84E-26 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03750 9a27b1ebd3621fe1602f2ce9866413f6 429 Gene3D G3DSA:1.20.1250.20 227 412 6.9E-5 T 06-07-2017 CAL12_RS03750 9a27b1ebd3621fe1602f2ce9866413f6 429 Gene3D G3DSA:1.20.1250.20 18 193 3.0E-7 T 06-07-2017 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 SUPERFAMILY SSF55811 23 155 1.9E-20 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 PRINTS PR00502 NUDIX hydrolase family signature 42 56 6.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 PRINTS PR00502 NUDIX hydrolase family signature 56 71 6.3E-5 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 Pfam PF00293 NUDIX domain 20 150 1.0E-13 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS18215 5c652fc5d40ec796f2f624b0a46088b0 157 Gene3D G3DSA:3.90.79.10 5 154 4.4E-24 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS08870 34bbe9ed1ed32a1f5dce27b921f6847d 245 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 236 2.9E-90 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAL12_RS08870 34bbe9ed1ed32a1f5dce27b921f6847d 245 SUPERFAMILY SSF63892 1 238 8.5E-96 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAL12_RS08870 34bbe9ed1ed32a1f5dce27b921f6847d 245 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 4 235 3.5E-100 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAL12_RS08870 34bbe9ed1ed32a1f5dce27b921f6847d 245 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 240 127.552 T 06-07-2017 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 CAL12_RS08870 34bbe9ed1ed32a1f5dce27b921f6847d 245 Gene3D G3DSA:3.20.20.70 1 239 8.7E-106 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS17825 b57e088df929c589b71db7f0f1ef233d 317 SUPERFAMILY SSF103481 216 310 1.44E-11 T 06-07-2017 CAL12_RS17825 b57e088df929c589b71db7f0f1ef233d 317 SUPERFAMILY SSF103481 53 161 5.49E-12 T 06-07-2017 CAL12_RS17825 b57e088df929c589b71db7f0f1ef233d 317 Pfam PF00892 EamA-like transporter family 172 307 6.3E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS17825 b57e088df929c589b71db7f0f1ef233d 317 Pfam PF00892 EamA-like transporter family 19 158 4.8E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS12715 9945f1d4f9ceec33e729416f3ca1f946 158 SUPERFAMILY SSF54593 12 138 1.21E-31 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS12715 9945f1d4f9ceec33e729416f3ca1f946 158 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 135 1.2E-10 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS12715 9945f1d4f9ceec33e729416f3ca1f946 158 Gene3D G3DSA:3.10.180.10 13 148 4.2E-29 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Pfam PF00580 UvrD/REP helicase N-terminal domain 19 150 7.3E-23 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Pfam PF00580 UvrD/REP helicase N-terminal domain 203 305 2.8E-25 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Gene3D G3DSA:3.40.50.300 17 307 4.7E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Gene3D G3DSA:3.40.50.300 578 644 8.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Gene3D G3DSA:3.40.50.300 320 428 8.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Gene3D G3DSA:1.10.486.10 429 558 1.6E-7 T 06-07-2017 CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Pfam PF13361 UvrD-like helicase C-terminal domain 578 640 2.3E-18 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 Pfam PF13361 UvrD-like helicase C-terminal domain 318 469 1.5E-20 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAL12_RS08075 528d40bb74eafae8c27fba2972f854cf 706 SUPERFAMILY SSF52540 12 646 1.55E-124 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 Gene3D G3DSA:3.40.190.10 46 152 9.1E-12 T 06-07-2017 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 SUPERFAMILY SSF53850 31 370 7.41E-98 T 06-07-2017 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PIRSF PIRSF019574 3 371 2.5E-136 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 Gene3D G3DSA:3.40.190.10 153 320 1.4E-65 T 06-07-2017 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 Pfam PF13416 Bacterial extracellular solute-binding protein 51 336 1.9E-36 T 06-07-2017 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 183 202 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 80 94 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 129 145 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 270 289 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 315 341 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 160 174 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 37 53 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 220 239 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 109 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS18070 2f68686d6bce16d3c16db98be2f9314c 371 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 53 74 1.3E-64 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS13470 cf879b735bae79801b0ba414a4bffd08 630 Gene3D G3DSA:3.40.50.1820 23 339 1.2E-103 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13470 cf879b735bae79801b0ba414a4bffd08 630 SUPERFAMILY SSF53474 56 336 8.96E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13470 cf879b735bae79801b0ba414a4bffd08 630 Gene3D G3DSA:3.40.50.1820 378 622 4.7E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13470 cf879b735bae79801b0ba414a4bffd08 630 Pfam PF12697 Alpha/beta hydrolase family 395 618 3.2E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13470 cf879b735bae79801b0ba414a4bffd08 630 SUPERFAMILY SSF53474 373 626 5.05E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13640 a570e95f5c077a70f08695c310e02c67 102 Pfam PF11625 Protein of unknown function (DUF3253) 6 84 2.2E-25 T 06-07-2017 IPR021660 Protein of unknown function DUF3253 CAL12_RS13640 a570e95f5c077a70f08695c310e02c67 102 SUPERFAMILY SSF46785 3 84 3.26E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13640 a570e95f5c077a70f08695c310e02c67 102 Gene3D G3DSA:1.10.10.10 3 84 1.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12490 c50153d557ec7e25f5a6a2b93a0dda5a 391 Pfam PF02653 Branched-chain amino acid transport system / permease component 75 345 2.6E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS12600 50bfa6238ceb1cf435990ac0345d69e1 456 Pfam PF03972 MmgE/PrpD family 11 440 2.1E-97 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS12600 50bfa6238ceb1cf435990ac0345d69e1 456 Gene3D G3DSA:3.30.1330.120 275 409 3.3E-16 T 06-07-2017 CAL12_RS12600 50bfa6238ceb1cf435990ac0345d69e1 456 SUPERFAMILY SSF103378 9 448 7.45E-93 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS20455 5d1276d5d04843b61b707313b0d3d6e1 130 Pfam PF07366 SnoaL-like polyketide cyclase 14 117 4.9E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS20455 5d1276d5d04843b61b707313b0d3d6e1 130 Gene3D G3DSA:3.10.450.50 7 116 3.5E-12 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS20455 5d1276d5d04843b61b707313b0d3d6e1 130 SUPERFAMILY SSF54427 7 119 1.96E-28 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 SUPERFAMILY SSF46785 7 75 2.79E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 Gene3D G3DSA:1.10.10.10 8 71 6.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 SMART SM00895 81 205 9.2E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 Pfam PF07729 FCD domain 85 204 4.2E-26 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 SUPERFAMILY SSF48008 79 205 3.4E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 2.5E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 SMART SM00345 13 71 3.1E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.1E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.1E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19085 cdccfad7fb962ad625ab25c9ff033f38 226 Gene3D G3DSA:1.20.120.530 75 210 1.2E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS16365 e1a9ff720e73241614522bde9b99d993 479 SUPERFAMILY SSF103473 255 468 3.01E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16365 e1a9ff720e73241614522bde9b99d993 479 SUPERFAMILY SSF103473 13 201 3.01E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16365 e1a9ff720e73241614522bde9b99d993 479 Gene3D G3DSA:1.20.1250.20 16 200 7.5E-27 T 06-07-2017 CAL12_RS16365 e1a9ff720e73241614522bde9b99d993 479 Gene3D G3DSA:1.20.1250.20 269 452 2.2E-9 T 06-07-2017 CAL12_RS16365 e1a9ff720e73241614522bde9b99d993 479 Pfam PF07690 Major Facilitator Superfamily 19 421 3.4E-47 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS09305 00181bfe513de15c93ab2222463ca89b 434 Pfam PF01757 Acyltransferase family 51 369 5.5E-26 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 Gene3D G3DSA:2.160.20.20 1 125 1.2E-11 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 Pfam PF12951 Passenger-associated-transport-repeat 96 124 8.0E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 Pfam PF12951 Passenger-associated-transport-repeat 9 36 5.5E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 95 125 4.5E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 9 37 4.2E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 SUPERFAMILY SSF51126 1 66 2.51E-5 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23645 cb7b9589b8ea4ac5b85b9d4fe92e9e2a 125 SUPERFAMILY SSF51126 45 124 9.1E-6 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS08670 0b6f4541c7eeb65eb81ccbeebbc365fb 173 SUPERFAMILY SSF51161 4 169 1.31E-37 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS08670 0b6f4541c7eeb65eb81ccbeebbc365fb 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 4.5E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS08670 0b6f4541c7eeb65eb81ccbeebbc365fb 173 Gene3D G3DSA:2.160.10.10 3 168 6.0E-40 T 06-07-2017 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 Gene3D G3DSA:3.40.1060.10 160 262 5.9E-25 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 ProSitePatterns PS00450 Aconitase family signature 1. 290 306 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 Gene3D G3DSA:3.30.499.10 274 418 1.1E-45 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 Gene3D G3DSA:3.30.499.10 1 157 6.0E-33 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 SUPERFAMILY SSF53732 1 419 1.23E-124 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 Pfam PF00330 Aconitase family (aconitate hydratase) 7 410 4.9E-85 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 416 3.5E-143 T 06-07-2017 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 PRINTS PR00415 Aconitase family signature 350 363 5.5E-12 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 PRINTS PR00415 Aconitase family signature 188 201 5.5E-12 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 PRINTS PR00415 Aconitase family signature 202 215 5.5E-12 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 PRINTS PR00415 Aconitase family signature 112 125 5.5E-12 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 PRINTS PR00415 Aconitase family signature 126 141 5.5E-12 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21870 201c12dbe739ebcbec6096f19ab61321 428 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 4 416 2.6E-136 T 06-07-2017 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS04115 5143efa20234da12c9f3838a4bfc2f7c 465 Gene3D G3DSA:3.90.1300.10 9 455 2.0E-124 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04115 5143efa20234da12c9f3838a4bfc2f7c 465 Pfam PF01425 Amidase 21 439 1.9E-96 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04115 5143efa20234da12c9f3838a4bfc2f7c 465 SUPERFAMILY SSF75304 8 456 2.09E-121 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04115 5143efa20234da12c9f3838a4bfc2f7c 465 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 9 453 5.9E-207 T 06-07-2017 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 Gene3D G3DSA:3.20.130.10 318 492 1.8E-66 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 331 492 3.1E-46 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 PIRSF PIRSF001394 1 509 3.2E-171 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 285 6.5E-48 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 Pfam PF05683 Fumarase C-terminus 293 493 6.9E-73 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 SUPERFAMILY SSF117457 324 492 3.66E-59 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS13095 9e663470ff434903203bea4826ba8929 516 Pfam PF05681 Fumarate hydratase (Fumerase) 12 288 3.7E-80 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 64 327 2.5E-78 T 06-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 PRINTS PR00605 Class IC cytochrome C signature 169 180 2.7E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 PRINTS PR00605 Class IC cytochrome C signature 211 233 2.7E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 PIRSF PIRSF000006 5 328 3.7E-95 T 06-07-2017 IPR004678 Cytochrome c oxidase cbb3-type, subunit III CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 71 115 1.3E-19 T 06-07-2017 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Gene3D G3DSA:1.10.760.10 93 115 2.1E-29 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Gene3D G3DSA:1.10.760.10 154 238 2.1E-29 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Gene3D G3DSA:1.10.760.10 245 335 2.4E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 SUPERFAMILY SSF46626 139 243 8.87E-32 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 SUPERFAMILY SSF46626 88 111 8.87E-32 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 248 321 1.1E-11 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 160 233 3.8E-14 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14345 91b225eb291e275bfb394a56fa1ae7a6 353 SUPERFAMILY SSF46626 246 335 2.1E-22 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 Pfam PF00248 Aldo/keto reductase family 19 285 8.2E-49 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 SUPERFAMILY SSF51430 16 286 6.55E-62 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 PRINTS PR00069 Aldo-keto reductase signature 220 244 4.5E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 PRINTS PR00069 Aldo-keto reductase signature 150 167 4.5E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 PRINTS PR00069 Aldo-keto reductase signature 49 73 4.5E-8 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS16425 3ed3424800d990cc2c1ce5b87f273364 290 Gene3D G3DSA:3.20.20.100 16 286 7.5E-58 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS02020 b3b515ea58bc6ffb106c972c239e2d66 327 Pfam PF04773 FecR protein 114 212 1.5E-16 T 06-07-2017 IPR006860 FecR protein CAL12_RS02020 b3b515ea58bc6ffb106c972c239e2d66 327 Pfam PF16220 Domain of unknown function (DUF4880) 13 55 1.3E-14 T 06-07-2017 IPR032623 FecR, N-terminal CAL12_RS02020 b3b515ea58bc6ffb106c972c239e2d66 327 PIRSF PIRSF018266 4 326 3.5E-92 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAL12_RS14680 ccb64fe8db1e1c04c016668bc58c8733 298 Pfam PF04909 Amidohydrolase 38 298 2.2E-39 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS14680 ccb64fe8db1e1c04c016668bc58c8733 298 Gene3D G3DSA:3.20.20.140 26 298 4.6E-94 T 06-07-2017 CAL12_RS14680 ccb64fe8db1e1c04c016668bc58c8733 298 SUPERFAMILY SSF51556 33 297 1.53E-72 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 SUPERFAMILY SSF51735 10 270 1.76E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 8.0E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.0E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 8.0E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.0E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 8.0E-19 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 Gene3D G3DSA:3.40.50.720 10 234 1.4E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.3E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 195 1.9E-4 T 06-07-2017 CAL12_RS20065 78689fbd3cf72c15b8b505b7b5c32ba7 334 Pfam PF00106 short chain dehydrogenase 10 196 3.7E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 Gene3D G3DSA:2.30.42.10 93 182 2.4E-18 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 SUPERFAMILY SSF50156 218 284 1.17E-14 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 SUPERFAMILY SSF50156 85 181 2.37E-15 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 443 1.7E-106 T 06-07-2017 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 SMART SM00228 112 184 4.0E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 SMART SM00228 208 275 6.5E-7 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 115 169 3.0E-9 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 Pfam PF02163 Peptidase family M50 7 429 2.6E-76 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAL12_RS12150 2415c816200dfe3b8484d54ba894f03c 444 Gene3D G3DSA:2.30.42.10 214 287 2.4E-16 T 06-07-2017 IPR001478 PDZ domain GO:0005515 CAL12_RS15145 0401b789dce082de4c827a4d0218cfd8 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 249 1.6E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15145 0401b789dce082de4c827a4d0218cfd8 262 SUPERFAMILY SSF161098 3 248 2.43E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15145 0401b789dce082de4c827a4d0218cfd8 262 Gene3D G3DSA:1.10.3720.10 7 250 1.3E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01320 aba22238152891993298106c00d86ed7 243 Pfam PF03737 Demethylmenaquinone methyltransferase 36 184 5.7E-26 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS01320 aba22238152891993298106c00d86ed7 243 Gene3D G3DSA:3.50.30.40 18 194 7.0E-38 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS01320 aba22238152891993298106c00d86ed7 243 SUPERFAMILY SSF89562 16 194 1.83E-35 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 406 2.0E-154 T 06-07-2017 CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 Pfam PF01960 ArgJ family 22 408 7.2E-139 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 408 1.8E-119 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 155.032 T 06-07-2017 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 SUPERFAMILY SSF56266 16 405 7.72E-137 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS25075 f2f61b00947b41c36757fdc5b2e36e28 408 Gene3D G3DSA:3.60.70.12 11 279 1.1E-94 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS15885 eb1bd6139f97353f1b02289aae8720d9 179 Gene3D G3DSA:3.10.640.10 1 178 6.7E-81 T 06-07-2017 CAL12_RS15885 eb1bd6139f97353f1b02289aae8720d9 179 PIRSF PIRSF011484 1 179 6.4E-72 T 06-07-2017 IPR009822 YaeQ CAL12_RS15885 eb1bd6139f97353f1b02289aae8720d9 179 SUPERFAMILY SSF52980 5 177 2.68E-72 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS15885 eb1bd6139f97353f1b02289aae8720d9 179 Pfam PF07152 YaeQ protein 1 172 1.9E-77 T 06-07-2017 IPR009822 YaeQ CAL12_RS15885 eb1bd6139f97353f1b02289aae8720d9 179 SMART SM01322 1 176 1.1E-118 T 06-07-2017 IPR009822 YaeQ CAL12_RS08315 4c541d4584919cdee07dbf370ceeddf7 324 Gene3D G3DSA:3.90.420.10 76 321 1.0E-65 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS08315 4c541d4584919cdee07dbf370ceeddf7 324 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 5 324 56.879 T 06-07-2017 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 CAL12_RS08315 4c541d4584919cdee07dbf370ceeddf7 324 SUPERFAMILY SSF56524 72 320 6.93E-86 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS08315 4c541d4584919cdee07dbf370ceeddf7 324 Pfam PF00174 Oxidoreductase molybdopterin binding domain 105 259 1.4E-27 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS07250 0082feccbf015136e2eb4f50870f9642 251 SMART SM00382 30 248 2.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07250 0082feccbf015136e2eb4f50870f9642 251 Gene3D G3DSA:3.40.50.300 2 246 1.9E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07250 0082feccbf015136e2eb4f50870f9642 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 6.3E-11 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS07250 0082feccbf015136e2eb4f50870f9642 251 Pfam PF00005 ABC transporter 22 177 6.0E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07250 0082feccbf015136e2eb4f50870f9642 251 SUPERFAMILY SSF52540 4 246 2.28E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15390 5df0aab948ce735cd25261ce23dd6734 337 SUPERFAMILY SSF52540 10 296 6.5E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15390 5df0aab948ce735cd25261ce23dd6734 337 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 45 175 5.1E-64 T 06-07-2017 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CAL12_RS15390 5df0aab948ce735cd25261ce23dd6734 337 Gene3D G3DSA:3.40.50.300 26 191 2.2E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15390 5df0aab948ce735cd25261ce23dd6734 337 PIRSF PIRSF002849 2 326 1.4E-131 T 06-07-2017 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted CAL12_RS15390 5df0aab948ce735cd25261ce23dd6734 337 Gene3D G3DSA:1.10.8.300 204 320 1.1E-38 T 06-07-2017 CAL12_RS07135 044623f64b413ec47cc6cbda12d9f9ce 261 Gene3D G3DSA:3.90.226.10 7 229 6.4E-64 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS07135 044623f64b413ec47cc6cbda12d9f9ce 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 221 2.1E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS07135 044623f64b413ec47cc6cbda12d9f9ce 261 SUPERFAMILY SSF52096 4 255 5.91E-63 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS19845 6e231afe97767b5e986b621d300e30f9 391 Pfam PF06580 Histidine kinase 167 245 1.9E-23 T 06-07-2017 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CAL12_RS19845 6e231afe97767b5e986b621d300e30f9 391 Gene3D G3DSA:3.30.565.10 220 303 3.1E-4 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS19845 6e231afe97767b5e986b621d300e30f9 391 SUPERFAMILY SSF55874 222 306 1.87E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 SUPERFAMILY SSF51735 121 304 8.47E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 Gene3D G3DSA:3.40.50.720 25 135 2.0E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 129 303 1.4E-51 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 26 334 3.9E-21 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 Gene3D G3DSA:3.40.50.720 136 306 3.2E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06825 a4a48761dbd5d1a84ed5f621e125f6e1 335 SUPERFAMILY SSF52283 25 156 1.3E-30 T 06-07-2017 CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 2 312 2.4E-70 T 06-07-2017 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 SMART SM00382 223 370 4.8E-5 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 Gene3D G3DSA:3.40.50.300 225 415 1.1E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 SUPERFAMILY SSF52540 220 415 1.53E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 Pfam PF00448 SRP54-type protein, GTPase domain 226 415 1.2E-31 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS11870 0bee5db2e4278b4e78080d45405d27ad 838 SMART SM00962 224 419 4.5E-48 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 67 242 9.9E-34 T 06-07-2017 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 SMART SM00342 290 372 1.4E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 Pfam PF12833 Helix-turn-helix domain 296 373 1.3E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 327 368 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 Gene3D G3DSA:1.10.10.60 326 376 1.7E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS23760 9fb4ea9c02dddf7d7a0da2d0da22df69 386 SUPERFAMILY SSF46689 326 376 1.11E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS08810 ccc01e2f04498ea78430feb0ee369fa0 256 SUPERFAMILY SSF53335 16 234 2.33E-35 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08810 ccc01e2f04498ea78430feb0ee369fa0 256 Gene3D G3DSA:3.40.50.150 17 245 2.6E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 Pfam PF00005 ABC transporter 19 167 2.2E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 Gene3D G3DSA:3.40.50.300 4 240 2.8E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 SMART SM00382 28 217 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 SUPERFAMILY SSF50331 243 345 5.33E-9 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS24920 9ea536f77587446365fc75c14fd4b6af 361 SUPERFAMILY SSF52540 4 248 4.15E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06080 76385995c565f3e3477c2fba6c382b92 291 Gene3D G3DSA:3.40.630.40 13 288 1.7E-97 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS06080 76385995c565f3e3477c2fba6c382b92 291 SUPERFAMILY SSF53187 14 288 1.57E-86 T 06-07-2017 CAL12_RS06080 76385995c565f3e3477c2fba6c382b92 291 Pfam PF05013 N-formylglutamate amidohydrolase 24 257 3.1E-68 T 06-07-2017 IPR007709 N-formylglutamate amidohydrolase CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 SUPERFAMILY SSF53822 28 383 1.83E-71 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 264 282 8.2E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 8.2E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 8.2E-8 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 Gene3D G3DSA:3.40.50.2300 29 229 4.9E-45 T 06-07-2017 CAL12_RS00335 bab5b25d89413d46869b963ee7cb92e0 392 Pfam PF13458 Periplasmic binding protein 29 380 7.4E-62 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 Gene3D G3DSA:3.40.718.10 5 342 1.3E-118 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 SUPERFAMILY SSF53659 3 352 1.06E-119 T 06-07-2017 CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 SMART SM01329 6 348 8.4E-181 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 3 352 3.6E-171 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CAL12_RS17855 11d0ea3f502f1ddce11b50bb176a135c 353 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 348 2.3E-86 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 Gene3D G3DSA:1.10.10.10 2 79 3.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 292 3.0E-116 T 06-07-2017 IPR017685 HTH-type transcriptional regulator ArgP CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 SUPERFAMILY SSF46785 2 109 2.56E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 7.0E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 SUPERFAMILY SSF53850 89 292 3.98E-19 T 06-07-2017 CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 Pfam PF03466 LysR substrate binding domain 89 287 5.0E-12 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS26480 47380eb0bfededa65d62bc7350c3d375 300 Gene3D G3DSA:3.40.190.10 92 198 2.0E-41 T 06-07-2017 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 Gene3D G3DSA:3.40.50.300 350 581 2.2E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 SUPERFAMILY SSF52540 342 588 4.13E-90 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 Pfam PF00005 ABC transporter 368 517 2.7E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 Pfam PF00664 ABC transporter transmembrane region 35 305 1.2E-46 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 SMART SM00382 376 549 2.5E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 Gene3D G3DSA:1.20.1560.10 20 333 5.2E-69 T 06-07-2017 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 20 590 2.4E-254 T 06-07-2017 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 CAL12_RS17945 7259f750cdcc5c7d86c62c9eef3b226e 592 SUPERFAMILY SSF90123 21 334 3.92E-71 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS23585 2ea8c5bfc5a435ca9306df267e4ae6ac 482 Pfam PF13520 Amino acid permease 28 424 7.1E-45 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAL12_RS23585 2ea8c5bfc5a435ca9306df267e4ae6ac 482 PIRSF PIRSF006060 4 474 2.5E-77 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAL12_RS03120 6a917108a4273c098889469c14927337 430 Pfam PF07969 Amidohydrolase family 40 396 1.7E-49 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS03120 6a917108a4273c098889469c14927337 430 Gene3D G3DSA:3.20.20.140 64 361 2.9E-108 T 06-07-2017 CAL12_RS03120 6a917108a4273c098889469c14927337 430 SUPERFAMILY SSF51338 362 408 8.95E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS03120 6a917108a4273c098889469c14927337 430 SUPERFAMILY SSF51338 1 52 8.95E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS03120 6a917108a4273c098889469c14927337 430 SUPERFAMILY SSF51556 52 371 2.2E-105 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS03120 6a917108a4273c098889469c14927337 430 Gene3D G3DSA:2.30.40.10 1 63 6.4E-17 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS27130 77a31ec9c0fee7035bef5946a4288927 357 Gene3D G3DSA:3.40.190.10 14 135 1.3E-20 T 06-07-2017 CAL12_RS27130 77a31ec9c0fee7035bef5946a4288927 357 Gene3D G3DSA:3.40.190.10 284 337 1.3E-20 T 06-07-2017 CAL12_RS27130 77a31ec9c0fee7035bef5946a4288927 357 Gene3D G3DSA:3.40.190.10 138 283 2.7E-29 T 06-07-2017 CAL12_RS27130 77a31ec9c0fee7035bef5946a4288927 357 SUPERFAMILY SSF53850 37 354 8.98E-57 T 06-07-2017 CAL12_RS27130 77a31ec9c0fee7035bef5946a4288927 357 Pfam PF13416 Bacterial extracellular solute-binding protein 57 319 2.4E-33 T 06-07-2017 CAL12_RS20310 3ad2845534654da7f04eb600d58602bd 890 SUPERFAMILY SSF55874 42 166 4.37E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS20310 3ad2845534654da7f04eb600d58602bd 890 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 54 173 2.1E-17 T 06-07-2017 CAL12_RS20310 3ad2845534654da7f04eb600d58602bd 890 Gene3D G3DSA:3.30.565.10 42 171 2.0E-17 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11820 6acd95ae9d9f64bddfec2c112c0ba852 130 Pfam PF00072 Response regulator receiver domain 5 117 1.0E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11820 6acd95ae9d9f64bddfec2c112c0ba852 130 Gene3D G3DSA:3.40.50.2300 3 123 2.8E-34 T 06-07-2017 CAL12_RS11820 6acd95ae9d9f64bddfec2c112c0ba852 130 SMART SM00448 3 118 3.3E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11820 6acd95ae9d9f64bddfec2c112c0ba852 130 SUPERFAMILY SSF52172 4 122 7.97E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 136 415 2.4E-52 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 14 436 9.7E-147 T 06-07-2017 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 Gene3D G3DSA:3.90.850.10 133 415 1.9E-101 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 Pfam PF09298 Fumarylacetoacetase N-terminal 29 130 3.0E-19 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 Gene3D G3DSA:2.30.30.230 14 132 4.1E-28 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 SUPERFAMILY SSF56529 132 435 3.27E-89 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS02760 c9fa0db537af18c2365aff30132db79e 438 SUPERFAMILY SSF63433 13 130 2.09E-27 T 06-07-2017 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 Gene3D G3DSA:3.40.1010.10 43 159 5.2E-38 T 06-07-2017 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 SUPERFAMILY SSF53790 41 280 1.18E-68 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 49 63 - T 06-07-2017 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 44 277 8.4E-81 T 06-07-2017 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 Gene3D G3DSA:3.30.950.10 160 280 3.0E-39 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS07020 5fffb62a4ac415c12ce29f1a74b83be3 291 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 45 253 4.6E-44 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS12955 4ca2e144149b72ed2cc1d6f3f3e498af 263 SUPERFAMILY SSF52540 6 232 9.71E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12955 4ca2e144149b72ed2cc1d6f3f3e498af 263 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS12955 4ca2e144149b72ed2cc1d6f3f3e498af 263 Gene3D G3DSA:3.40.50.300 4 223 6.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12955 4ca2e144149b72ed2cc1d6f3f3e498af 263 SMART SM00382 33 223 7.6E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12955 4ca2e144149b72ed2cc1d6f3f3e498af 263 Pfam PF00005 ABC transporter 24 164 3.4E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 Pfam PF03466 LysR substrate binding domain 89 283 2.8E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 Gene3D G3DSA:3.40.190.10 182 250 4.6E-6 T 06-07-2017 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 SUPERFAMILY SSF46785 1 110 2.57E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 SUPERFAMILY SSF53850 89 284 2.53E-35 T 06-07-2017 CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 Gene3D G3DSA:1.10.10.10 1 84 3.6E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16715 5238c26a8f9c87408dbfb06a80982e61 295 Gene3D G3DSA:3.40.190.10 91 181 8.8E-15 T 06-07-2017 CAL12_RS05890 a666c16004a69fc33399ff87b5143088 329 Pfam PF04909 Amidohydrolase 3 327 2.7E-42 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS05890 a666c16004a69fc33399ff87b5143088 329 Gene3D G3DSA:3.20.20.140 2 327 4.0E-84 T 06-07-2017 CAL12_RS05890 a666c16004a69fc33399ff87b5143088 329 SUPERFAMILY SSF51556 1 327 8.04E-75 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS04685 caf1b3fd98d0b2551e38b620b0cd04e6 229 Pfam PF08279 HTH domain 6 59 3.0E-17 T 06-07-2017 IPR013196 Helix-turn-helix, type 11 CAL12_RS04685 caf1b3fd98d0b2551e38b620b0cd04e6 229 Gene3D G3DSA:1.10.10.10 1 63 2.8E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04685 caf1b3fd98d0b2551e38b620b0cd04e6 229 SUPERFAMILY SSF46785 1 62 2.93E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04685 caf1b3fd98d0b2551e38b620b0cd04e6 229 Pfam PF13280 WYL domain 137 225 9.9E-12 T 06-07-2017 IPR026881 WYL domain CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 Gene3D G3DSA:1.25.50.10 573 897 2.6E-118 T 06-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 297 312 1.3E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 179 194 1.3E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 316 328 1.3E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 261 271 1.3E-7 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 Gene3D G3DSA:1.10.390.10 311 470 7.1E-31 T 06-07-2017 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 Pfam PF01433 Peptidase family M1 110 398 8.7E-62 T 06-07-2017 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 896 0.0 T 06-07-2017 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 SUPERFAMILY SSF55486 208 470 2.01E-71 T 06-07-2017 CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 Pfam PF11940 Domain of unknown function (DUF3458) 478 854 7.8E-137 T 06-07-2017 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal CAL12_RS17805 e6b29100786c57d53559165b7ef81699 900 SUPERFAMILY SSF63737 9 195 3.4E-41 T 06-07-2017 CAL12_RS21035 94e6ffe52fb5359c7330a75b8d501d49 355 Pfam PF13816 Haem-containing dehydratase 41 341 1.0E-76 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAL12_RS21035 94e6ffe52fb5359c7330a75b8d501d49 355 SUPERFAMILY SSF54909 46 115 2.15E-5 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS21035 94e6ffe52fb5359c7330a75b8d501d49 355 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 1 342 6.0E-41 T 06-07-2017 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 CAL12_RS21035 94e6ffe52fb5359c7330a75b8d501d49 355 Gene3D G3DSA:3.30.70.900 52 111 4.2E-4 T 06-07-2017 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 Gene3D G3DSA:2.40.50.140 1 66 3.3E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 SMART SM00357 3 67 3.8E-29 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 PRINTS PR00050 Cold shock protein signature 40 58 1.3E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 PRINTS PR00050 Cold shock protein signature 25 34 1.3E-15 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.0E-30 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 SUPERFAMILY SSF50249 1 66 1.07E-24 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS17705 b1da47d39b1beb40c7594b7c41d03db5 67 PIRSF PIRSF002599 1 67 4.1E-24 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 PIRSF PIRSF005624 1 207 1.5E-44 T 06-07-2017 CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 Gene3D G3DSA:3.40.50.300 10 177 1.3E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 11 206 1.6E-98 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 Hamap MF_01389 Urease accessory protein UreG [ureG]. 9 207 46.328 T 06-07-2017 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 181 9.6E-37 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS18400 3e8ab88a853bf5bc6c4dba2964c00829 208 SUPERFAMILY SSF52540 6 202 4.02E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 SUPERFAMILY SSF52467 177 321 2.55E-6 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 SUPERFAMILY SSF52518 337 512 2.5E-33 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 509 3.7E-21 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 SUPERFAMILY SSF52518 1 178 2.36E-37 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 Gene3D G3DSA:3.40.50.970 1 178 2.0E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 Gene3D G3DSA:3.40.50.970 332 512 1.5E-37 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS09045 d8f8ab28b0003330ac5b38b55b0b19eb 512 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 162 2.2E-35 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS24030 100638cde6f287d36e62d9af96dbc414 523 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 226 6.2E-17 T 06-07-2017 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 Gene3D G3DSA:1.20.58.180 228 308 1.5E-38 T 06-07-2017 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 18 303 60.445 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 150 170 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 124 148 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 263 279 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 72 87 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 93 113 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 173 188 9.9E-66 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 20 302 4.8E-149 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 SUPERFAMILY SSF55681 19 302 7.21E-132 T 06-07-2017 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 Gene3D G3DSA:3.30.930.10 16 225 1.4E-105 T 06-07-2017 CAL12_RS06355 8574e7f0f382f16c845f78b41349fa75 319 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 19 309 3.9E-158 T 06-07-2017 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 Gene3D G3DSA:4.10.520.10 1 91 6.0E-31 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.1E-16 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.1E-16 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.1E-16 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 SUPERFAMILY SSF47729 1 91 1.27E-27 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 4.1E-37 T 06-07-2017 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.3E-27 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS18915 fb318469a30f459706c0dceed777fa97 120 SMART SM00411 1 91 3.5E-35 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS21820 2f5ce135048a1d1c3c9a49a08a85598c 226 SUPERFAMILY SSF161098 13 201 3.01E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21820 2f5ce135048a1d1c3c9a49a08a85598c 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 53 215 1.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21820 2f5ce135048a1d1c3c9a49a08a85598c 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 8.9E-30 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS21820 2f5ce135048a1d1c3c9a49a08a85598c 226 Gene3D G3DSA:1.10.3720.10 10 215 3.6E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05830 afabfeaa947c87c77353b57a92efbbf1 324 PIRSF PIRSF017082 3 323 2.2E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05830 afabfeaa947c87c77353b57a92efbbf1 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 1.5E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05830 afabfeaa947c87c77353b57a92efbbf1 324 SUPERFAMILY SSF53850 114 285 1.71E-8 T 06-07-2017 CAL12_RS11360 3a150e3e5f9514a1f815528caa5e13e4 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 1.2E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS19520 2343b4b871db61ae92e6651c8f410582 386 SUPERFAMILY SSF53822 26 382 6.54E-71 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS19520 2343b4b871db61ae92e6651c8f410582 386 Gene3D G3DSA:3.40.50.2300 25 219 5.3E-42 T 06-07-2017 CAL12_RS19520 2343b4b871db61ae92e6651c8f410582 386 Pfam PF13458 Periplasmic binding protein 25 378 7.3E-45 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 SUPERFAMILY SSF53850 95 294 2.99E-41 T 06-07-2017 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 Gene3D G3DSA:3.40.190.10 96 178 1.6E-8 T 06-07-2017 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 Pfam PF03466 LysR substrate binding domain 95 292 1.3E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.9E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 Gene3D G3DSA:3.40.190.10 179 261 2.8E-29 T 06-07-2017 CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 SUPERFAMILY SSF46785 3 85 1.84E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04145 073d1102994881a758d1b7459a33ddb5 296 Gene3D G3DSA:1.10.10.10 2 86 2.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 Gene3D G3DSA:1.20.1050.10 92 207 3.3E-23 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 Gene3D G3DSA:3.40.30.10 1 91 3.9E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 SUPERFAMILY SSF52833 1 92 1.19E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 Pfam PF13409 Glutathione S-transferase, N-terminal domain 10 77 2.8E-12 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 Pfam PF00043 Glutathione S-transferase, C-terminal domain 141 203 3.0E-7 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS16725 8e60cb7a2e651b9d744afc5317ca9dee 217 SUPERFAMILY SSF47616 82 207 3.76E-20 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS08925 48de6ce88a9d7007b765e37090917378 135 Gene3D G3DSA:2.60.40.790 13 133 6.1E-19 T 06-07-2017 IPR008978 HSP20-like chaperone CAL12_RS08925 48de6ce88a9d7007b765e37090917378 135 Pfam PF00011 Hsp20/alpha crystallin family 44 133 7.9E-10 T 06-07-2017 IPR002068 Alpha crystallin/Hsp20 domain CAL12_RS08925 48de6ce88a9d7007b765e37090917378 135 SUPERFAMILY SSF49764 22 133 5.23E-19 T 06-07-2017 IPR008978 HSP20-like chaperone CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 115 3.5E-16 T 06-07-2017 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 Gene3D G3DSA:3.40.50.2020 4 157 6.0E-28 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 Gene3D G3DSA:3.40.50.2020 158 275 1.1E-17 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 289 2.4E-53 T 06-07-2017 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 Pfam PF00156 Phosphoribosyl transferase domain 151 268 1.2E-13 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 SUPERFAMILY SSF53271 160 289 8.26E-22 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 SUPERFAMILY SSF53271 5 157 1.91E-36 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS24520 662dbc419b12e32dad848513acad43f6 293 SMART SM01400 3 118 5.3E-32 T 06-07-2017 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.774 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 Pfam PF01632 Ribosomal protein L35 2 62 1.2E-25 T 06-07-2017 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 SUPERFAMILY SSF143034 2 64 1.23E-23 T 06-07-2017 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 06-07-2017 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.7E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.7E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.7E-18 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAL12_RS09925 558236c5b0aed14d8be5e08576dc15ed 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.6E-27 T 06-07-2017 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CAL12_RS26490 535fe4d133beb856091781e568b9c1cd 324 PIRSF PIRSF017082 1 324 4.3E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26490 535fe4d133beb856091781e568b9c1cd 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 1.9E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26490 535fe4d133beb856091781e568b9c1cd 324 SUPERFAMILY SSF53850 115 289 3.32E-15 T 06-07-2017 CAL12_RS26490 535fe4d133beb856091781e568b9c1cd 324 Gene3D G3DSA:3.40.190.10 129 229 5.7E-4 T 06-07-2017 CAL12_RS25875 adb6f5d673eeb09b11bc22871553c297 108 Gene3D G3DSA:3.40.30.10 8 102 6.6E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25875 adb6f5d673eeb09b11bc22871553c297 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 1.4E-43 T 06-07-2017 IPR004480 Monothiol glutaredoxin-related CAL12_RS25875 adb6f5d673eeb09b11bc22871553c297 108 PIRSF PIRSF005894 1 108 3.5E-46 T 06-07-2017 IPR014434 Monothiol glutaredoxin CAL12_RS25875 adb6f5d673eeb09b11bc22871553c297 108 SUPERFAMILY SSF52833 1 106 2.38E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25875 adb6f5d673eeb09b11bc22871553c297 108 Pfam PF00462 Glutaredoxin 17 82 2.0E-19 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAL12_RS02845 4678fceb9004023a078ea441eef805b2 380 Pfam PF13776 Domain of unknown function (DUF4172) 8 89 1.3E-29 T 06-07-2017 IPR025230 Domain of unknown function DUF4172 CAL12_RS02845 4678fceb9004023a078ea441eef805b2 380 SUPERFAMILY SSF140931 103 300 2.09E-36 T 06-07-2017 IPR003812 Fido domain CAL12_RS02845 4678fceb9004023a078ea441eef805b2 380 Gene3D G3DSA:1.10.3290.10 30 302 1.7E-58 T 06-07-2017 IPR003812 Fido domain CAL12_RS02845 4678fceb9004023a078ea441eef805b2 380 Pfam PF02661 Fic/DOC family 118 230 2.0E-18 T 06-07-2017 IPR003812 Fido domain CAL12_RS02845 4678fceb9004023a078ea441eef805b2 380 Gene3D G3DSA:1.10.10.10 306 372 1.5E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 Pfam PF13616 PPIC-type PPIASE domain 251 368 3.8E-27 T 06-07-2017 CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 307 328 - T 06-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 Pfam PF13624 SurA N-terminal domain 1 162 7.3E-52 T 06-07-2017 CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 SUPERFAMILY SSF54534 258 368 1.11E-28 T 06-07-2017 CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 Gene3D G3DSA:3.10.50.40 257 392 2.7E-41 T 06-07-2017 CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 SUPERFAMILY SSF109998 42 166 1.07E-34 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS15755 7b785e649ac9365fd03607b636686b97 655 SUPERFAMILY SSF109998 200 236 1.07E-34 T 06-07-2017 IPR027304 Trigger factor/SurA domain CAL12_RS13750 b373c9d1a4e96427fb83080aca2c2dfc 480 Pfam PF09084 NMT1/THI5 like 119 273 1.4E-9 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS13750 b373c9d1a4e96427fb83080aca2c2dfc 480 Gene3D G3DSA:3.40.190.10 137 258 1.3E-15 T 06-07-2017 CAL12_RS13750 b373c9d1a4e96427fb83080aca2c2dfc 480 SUPERFAMILY SSF53850 71 327 4.74E-40 T 06-07-2017 CAL12_RS13750 b373c9d1a4e96427fb83080aca2c2dfc 480 SUPERFAMILY SSF160387 380 475 3.14E-6 T 06-07-2017 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 Gene3D G3DSA:3.20.20.70 33 337 1.3E-75 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 48 59 - T 06-07-2017 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 SUPERFAMILY SSF102114 33 318 1.03E-73 T 06-07-2017 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 SMART SM00729 42 256 1.0E-9 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 Pfam PF04055 Radical SAM superfamily 46 214 1.4E-26 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 34 372 6.0E-110 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 33 372 39.945 T 06-07-2017 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 Pfam PF13394 4Fe-4S single cluster domain 49 141 2.1E-7 T 06-07-2017 CAL12_RS23940 e96ea3c53d0221b89f049dcc43d16ae5 372 Pfam PF06463 Molybdenum Cofactor Synthesis C 224 348 7.5E-34 T 06-07-2017 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23425 c5f11fd324136385673ea8a6263fe105 445 SUPERFAMILY SSF53067 145 324 1.17E-19 T 06-07-2017 CAL12_RS23425 c5f11fd324136385673ea8a6263fe105 445 Gene3D G3DSA:3.30.420.40 177 341 7.7E-17 T 06-07-2017 CAL12_RS05860 bcb666be172302ba74a5835e7b133fcd 186 Gene3D G3DSA:3.30.1330.40 68 182 3.6E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS05860 bcb666be172302ba74a5835e7b133fcd 186 Pfam PF01042 Endoribonuclease L-PSP 68 180 7.8E-19 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS05860 bcb666be172302ba74a5835e7b133fcd 186 SUPERFAMILY SSF55298 67 181 1.15E-26 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS06010 b5e625a8f5659bf524785e1bebe3bee3 417 SUPERFAMILY SSF53822 31 409 1.67E-89 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS06010 b5e625a8f5659bf524785e1bebe3bee3 417 Pfam PF13433 Periplasmic binding protein domain 32 408 2.1E-171 T 06-07-2017 CAL12_RS06010 b5e625a8f5659bf524785e1bebe3bee3 417 Gene3D G3DSA:3.40.50.2300 147 345 4.6E-73 T 06-07-2017 CAL12_RS06010 b5e625a8f5659bf524785e1bebe3bee3 417 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 32 405 4.1E-178 T 06-07-2017 IPR017777 ABC transporter, urea, substrate-binding, UrtA CAL12_RS01665 b26f44f96caed7908c6e06fb7954dbdb 201 Pfam PF13580 SIS domain 15 150 5.7E-35 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS01665 b26f44f96caed7908c6e06fb7954dbdb 201 Gene3D G3DSA:3.40.50.10490 6 194 1.1E-60 T 06-07-2017 CAL12_RS01665 b26f44f96caed7908c6e06fb7954dbdb 201 SUPERFAMILY SSF53697 6 195 2.43E-56 T 06-07-2017 CAL12_RS01665 b26f44f96caed7908c6e06fb7954dbdb 201 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 7 196 36.193 T 06-07-2017 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 52 65 - T 06-07-2017 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 18 274 32.487 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 15 249 3.1E-68 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 Gene3D G3DSA:3.20.20.70 7 276 9.8E-94 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 SUPERFAMILY SSF51366 6 253 1.04E-84 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS08265 53b953eb5f4e75af90aaf8239a38eb08 285 Pfam PF00290 Tryptophan synthase alpha chain 12 256 1.2E-83 T 06-07-2017 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS19560 43c2db2c3a4df2f2e6ffdc1116058de3 376 SMART SM00771 232 352 5.9E-19 T 06-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 CAL12_RS19560 43c2db2c3a4df2f2e6ffdc1116058de3 376 Gene3D G3DSA:3.30.1400.10 297 354 6.4E-9 T 06-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 CAL12_RS19560 43c2db2c3a4df2f2e6ffdc1116058de3 376 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 298 350 4.8E-8 T 06-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 CAL12_RS19560 43c2db2c3a4df2f2e6ffdc1116058de3 376 SUPERFAMILY SSF64383 249 358 1.44E-11 T 06-07-2017 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 SUPERFAMILY SSF51905 283 404 2.03E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 SUPERFAMILY SSF51905 169 216 2.03E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 SUPERFAMILY SSF51905 4 221 2.56E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 Gene3D G3DSA:3.40.50.720 175 194 9.3E-5 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 9 199 2.7E-26 T 06-07-2017 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 2.1E-7 T 06-07-2017 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.1E-7 T 06-07-2017 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 128 137 2.1E-7 T 06-07-2017 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 Gene3D G3DSA:3.50.50.60 372 402 1.7E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14420 465594be7fd5b0b5c443eb8315edd567 416 Gene3D G3DSA:3.50.50.60 4 174 1.7E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 SUPERFAMILY SSF158472 338 387 4.71E-11 T 06-07-2017 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 SMART SM00331 440 663 0.0041 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 466 663 2.0E-18 T 06-07-2017 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 SMART SM00304 338 390 1.5E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 Pfam PF00672 HAMP domain 320 386 3.5E-15 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS25030 92d91e5dd665dd1260cd54817ae790a0 664 Gene3D G3DSA:3.30.450.20 173 302 6.6E-7 T 06-07-2017 CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SMART SM00052 468 711 1.1E-98 T 06-07-2017 IPR001633 EAL domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Gene3D G3DSA:3.30.450.40 116 173 2.7E-6 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Pfam PF00990 Diguanylate cyclase, GGDEF domain 301 453 2.4E-35 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SMART SM00086 249 290 8.5E-6 T 06-07-2017 IPR001610 PAC motif CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 172 296 1.9E-7 T 06-07-2017 IPR000014 PAS domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SUPERFAMILY SSF55781 33 174 7.85E-10 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SUPERFAMILY SSF55073 306 460 1.18E-39 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SUPERFAMILY SSF55785 164 288 6.11E-12 T 06-07-2017 IPR000014 PAS domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Pfam PF08447 PAS fold 198 283 7.8E-9 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Gene3D G3DSA:3.30.70.270 302 465 5.2E-45 T 06-07-2017 CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Gene3D G3DSA:3.20.20.450 471 710 7.5E-80 T 06-07-2017 IPR001633 EAL domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SMART SM00267 290 458 1.5E-45 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Pfam PF00563 EAL domain 474 706 5.4E-68 T 06-07-2017 IPR001633 EAL domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 299 457 1.5E-31 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 SUPERFAMILY SSF141868 474 710 9.29E-75 T 06-07-2017 IPR001633 EAL domain CAL12_RS22015 2d83eb7a4512376b15a2d8434f560b1f 713 Gene3D G3DSA:3.30.450.20 174 288 2.4E-15 T 06-07-2017 CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 Pfam PF00582 Universal stress protein family 12 146 1.5E-25 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 Pfam PF00582 Universal stress protein family 157 288 3.0E-18 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 PRINTS PR01438 Universal stress protein signature 266 288 4.1E-8 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 PRINTS PR01438 Universal stress protein signature 10 28 4.1E-8 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 PRINTS PR01438 Universal stress protein signature 248 260 4.1E-8 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 SUPERFAMILY SSF52402 12 147 1.84E-27 T 06-07-2017 CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 Gene3D G3DSA:3.40.50.620 148 290 4.6E-24 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 Gene3D G3DSA:3.40.50.620 9 147 3.8E-29 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25345 161da5105c840774a9d0ae717a21cee4 293 SUPERFAMILY SSF52402 157 290 4.35E-22 T 06-07-2017 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 PIRSF PIRSF000103 2 295 2.0E-74 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 SUPERFAMILY SSF48179 164 293 5.37E-36 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 163 4.2E-47 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 9 22 - T 06-07-2017 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 Gene3D G3DSA:3.40.50.720 5 164 2.7E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06160 d181eab186df30213187c99c752209d2 305 SUPERFAMILY SSF51735 6 164 2.18E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06160 d181eab186df30213187c99c752209d2 305 Gene3D G3DSA:1.10.1040.10 166 291 6.3E-39 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 284 7.2E-36 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS06160 d181eab186df30213187c99c752209d2 305 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 6 293 1.3E-114 T 06-07-2017 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 CAL12_RS13210 06d657367de716c1b70aa14ac4f62cc4 362 PIRSF PIRSF017082 34 360 4.0E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13210 06d657367de716c1b70aa14ac4f62cc4 362 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 86 357 1.1E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 Gene3D G3DSA:3.30.1490.20 129 190 1.3E-16 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 Pfam PF02222 ATP-grasp domain 125 295 7.3E-45 T 06-07-2017 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 Gene3D G3DSA:3.40.50.20 15 122 2.0E-36 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 19 391 2.8E-114 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 18 388 40.411 T 06-07-2017 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 SUPERFAMILY SSF51246 319 401 4.94E-15 T 06-07-2017 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 SUPERFAMILY SSF52440 15 111 5.04E-27 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 Gene3D G3DSA:3.30.470.20 192 401 7.0E-64 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS05230 89605c9cde40cccf8bdf63f654a28054 417 SUPERFAMILY SSF56059 114 315 8.0E-55 T 06-07-2017 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 Gene3D G3DSA:3.10.20.30 10 85 9.1E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 Gene3D G3DSA:1.10.150.120 118 189 2.4E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 68 1.9E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 Pfam PF01799 [2Fe-2S] binding domain 118 182 2.5E-22 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 SUPERFAMILY SSF47741 121 188 2.75E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03315 6a80f62a9b9fd5c4b8a01b3ae82f3a1d 202 SUPERFAMILY SSF54292 6 88 1.44E-22 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 Pfam PF03466 LysR substrate binding domain 95 299 3.2E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 Gene3D G3DSA:3.40.190.10 182 271 2.6E-26 T 06-07-2017 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 Gene3D G3DSA:1.10.10.10 9 94 2.9E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 Gene3D G3DSA:3.40.190.10 97 181 1.1E-17 T 06-07-2017 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 SUPERFAMILY SSF46785 6 119 4.38E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 SUPERFAMILY SSF53850 96 304 4.24E-33 T 06-07-2017 CAL12_RS05975 5829bd3ee9ccfe298e5b75dcb90ef4ca 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 70 2.9E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 SUPERFAMILY SSF48008 81 216 6.28E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 SMART SM00895 85 208 9.5E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 Gene3D G3DSA:1.20.120.530 78 219 1.3E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 Gene3D G3DSA:1.10.10.10 16 73 1.9E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 5.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 5.5E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 SUPERFAMILY SSF46785 16 79 1.54E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 SMART SM00345 17 75 3.8E-7 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 73 1.1E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS22355 2c4b3cdb247f5ee902ea1f917f9eb8c7 234 Pfam PF07729 FCD domain 86 207 2.8E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Pfam PF10396 GTP-binding protein TrmE N-terminus 8 125 4.1E-38 T 06-07-2017 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 224 244 9.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 291 309 9.6E-6 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 7 452 32.719 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Pfam PF12631 MnmE helical domain 128 449 2.1E-54 T 06-07-2017 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:3.30.1360.120 8 126 2.7E-41 T 06-07-2017 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:3.40.50.300 222 253 2.5E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 SUPERFAMILY SSF52540 73 157 1.54E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 SUPERFAMILY SSF52540 193 370 1.54E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Pfam PF01926 50S ribosome-binding GTPase 224 338 3.9E-24 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:1.20.120.430 127 187 2.6E-52 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:1.20.120.430 254 276 2.6E-52 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:1.20.120.430 381 452 2.6E-52 T 06-07-2017 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 Gene3D G3DSA:3.40.50.300 291 373 6.8E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 13 452 3.5E-98 T 06-07-2017 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 CAL12_RS27895 7b0b2875fa2c06083127c597171031cf 452 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 223 343 1.5E-20 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 Pfam PF04542 Sigma-70 region 2 15 80 9.2E-12 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 Pfam PF08281 Sigma-70, region 4 112 163 6.3E-16 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 Gene3D G3DSA:1.10.10.10 109 163 3.2E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 SUPERFAMILY SSF88659 107 163 1.81E-14 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 SUPERFAMILY SSF88946 12 101 7.46E-14 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 8.3E-18 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11020 365112be4543e22eb5bdc7bb1ba9b1ba 171 Gene3D G3DSA:1.10.1740.10 12 103 1.8E-11 T 06-07-2017 CAL12_RS02450 b1a2062e9440373b62c81b32c34cfa2b 252 Gene3D G3DSA:3.30.2010.10 68 147 6.1E-21 T 06-07-2017 CAL12_RS02450 b1a2062e9440373b62c81b32c34cfa2b 252 Pfam PF01435 Peptidase family M48 72 247 4.0E-27 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 32 89 1.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 Gene3D G3DSA:1.10.10.10 9 134 1.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 SUPERFAMILY SSF53850 195 345 1.15E-12 T 06-07-2017 CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 SUPERFAMILY SSF46785 30 145 1.9E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 Pfam PF12727 PBP superfamily domain 153 330 2.3E-52 T 06-07-2017 IPR024370 PBP domain CAL12_RS23945 98b076d2ce250c5152e7ee6c85952029 365 Gene3D G3DSA:3.40.190.10 210 312 1.5E-11 T 06-07-2017 CAL12_RS10445 36c8c920198daad112ff4c1b5840eb2f 345 Pfam PF13343 Bacterial extracellular solute-binding protein 89 330 2.7E-33 T 06-07-2017 CAL12_RS10445 36c8c920198daad112ff4c1b5840eb2f 345 Gene3D G3DSA:3.40.190.10 36 135 3.6E-16 T 06-07-2017 CAL12_RS10445 36c8c920198daad112ff4c1b5840eb2f 345 Gene3D G3DSA:3.40.190.10 278 308 3.6E-16 T 06-07-2017 CAL12_RS10445 36c8c920198daad112ff4c1b5840eb2f 345 Gene3D G3DSA:3.40.190.10 138 277 1.2E-28 T 06-07-2017 CAL12_RS10445 36c8c920198daad112ff4c1b5840eb2f 345 SUPERFAMILY SSF53850 36 341 9.93E-49 T 06-07-2017 CAL12_RS19950 5a461d379b726edf13beee7b4e470557 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 6.5E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19950 5a461d379b726edf13beee7b4e470557 328 SUPERFAMILY SSF53850 115 290 1.3E-16 T 06-07-2017 CAL12_RS19950 5a461d379b726edf13beee7b4e470557 328 PIRSF PIRSF017082 1 327 4.0E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19950 5a461d379b726edf13beee7b4e470557 328 Gene3D G3DSA:3.40.190.10 131 249 1.6E-4 T 06-07-2017 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 17 42 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 195 215 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 296 325 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 402 431 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 450 479 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 373 400 2.8E-61 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 Gene3D G3DSA:1.10.287.950 295 494 4.5E-58 T 06-07-2017 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 521 2.3E-58 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 SMART SM00283 275 522 2.4E-83 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 Pfam PF00672 HAMP domain 204 270 2.4E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 SMART SM00304 222 274 1.1E-9 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 SMART SM00304 97 148 44.0 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 Pfam PF02203 Tar ligand binding domain homologue 17 183 2.0E-28 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS03905 17ed2c65a1182d0ad0bd6a9cbd69f0d9 542 SUPERFAMILY SSF58104 242 524 1.7E-72 T 06-07-2017 CAL12_RS19935 2a4910f478ba744a53679dd244f58f4e 265 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 7 254 6.0E-57 T 06-07-2017 IPR005226 UPF0014 family CAL12_RS19935 2a4910f478ba744a53679dd244f58f4e 265 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 250 2.4E-74 T 06-07-2017 IPR005226 UPF0014 family CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 SUPERFAMILY SSF53187 16 63 1.31E-34 T 06-07-2017 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 SUPERFAMILY SSF53187 212 407 1.31E-34 T 06-07-2017 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 Gene3D G3DSA:3.50.30.30 88 202 4.9E-10 T 06-07-2017 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 Pfam PF02225 PA domain 97 188 4.1E-7 T 06-07-2017 IPR003137 PA domain CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 SUPERFAMILY SSF52025 92 194 1.44E-11 T 06-07-2017 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 Pfam PF04389 Peptidase family M28 224 408 4.7E-23 T 06-07-2017 IPR007484 Peptidase M28 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 Gene3D G3DSA:3.40.630.10 219 411 3.9E-42 T 06-07-2017 CAL12_RS01950 8123d129c9138f928429ac4dd67c96df 428 Gene3D G3DSA:3.40.630.10 16 67 3.9E-42 T 06-07-2017 CAL12_RS24975 ef44619ff329aa86ecf37da6f9f59b52 227 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 217 24.894 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS24975 ef44619ff329aa86ecf37da6f9f59b52 227 SUPERFAMILY SSF51391 6 208 2.22E-60 T 06-07-2017 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS24975 ef44619ff329aa86ecf37da6f9f59b52 227 Gene3D G3DSA:3.20.20.70 7 209 4.7E-60 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS24975 ef44619ff329aa86ecf37da6f9f59b52 227 Pfam PF02581 Thiamine monophosphate synthase/TENI 10 194 1.1E-54 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS24975 ef44619ff329aa86ecf37da6f9f59b52 227 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 207 1.4E-51 T 06-07-2017 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CAL12_RS00145 288b3477dcb2296398a8e1bd4d9d43ce 150 Gene3D G3DSA:3.10.129.10 15 145 3.1E-28 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00145 288b3477dcb2296398a8e1bd4d9d43ce 150 SUPERFAMILY SSF54637 12 147 2.43E-26 T 06-07-2017 IPR029069 HotDog domain CAL12_RS00145 288b3477dcb2296398a8e1bd4d9d43ce 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 37 140 5.1E-16 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAL12_RS00145 288b3477dcb2296398a8e1bd4d9d43ce 150 Pfam PF03061 Thioesterase superfamily 61 130 2.9E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS22245 e06b1fa426f968f11877576fe5a873e8 186 Pfam PF04366 Las17-binding protein actin regulator 99 183 1.3E-8 T 06-07-2017 IPR007461 Ysc84 actin-binding domain CAL12_RS15610 705c88904ca139b9763d1f9f957c3b00 300 SUPERFAMILY SSF103481 190 289 5.62E-15 T 06-07-2017 CAL12_RS15610 705c88904ca139b9763d1f9f957c3b00 300 Pfam PF00892 EamA-like transporter family 155 285 1.1E-16 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS15610 705c88904ca139b9763d1f9f957c3b00 300 Pfam PF00892 EamA-like transporter family 9 140 5.6E-9 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS15610 705c88904ca139b9763d1f9f957c3b00 300 SUPERFAMILY SSF103481 40 140 2.09E-10 T 06-07-2017 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 SUPERFAMILY SSF51905 10 221 1.75E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 SUPERFAMILY SSF51905 314 372 1.75E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Gene3D G3DSA:3.30.9.10 88 142 9.8E-9 T 06-07-2017 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Gene3D G3DSA:3.30.9.10 221 311 9.8E-9 T 06-07-2017 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Gene3D G3DSA:3.50.50.60 7 84 2.4E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Gene3D G3DSA:3.50.50.60 314 372 2.4E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Gene3D G3DSA:3.50.50.60 143 220 2.4E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS07115 820237703d8cc2537a1dcf9d26a63d06 387 Pfam PF01266 FAD dependent oxidoreductase 10 353 1.5E-59 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 Gene3D G3DSA:3.50.50.60 10 185 2.0E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 Gene3D G3DSA:3.50.50.60 281 362 2.0E-40 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 Pfam PF01494 FAD binding domain 11 353 4.8E-26 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 1.2E-21 T 06-07-2017 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 159 174 1.2E-21 T 06-07-2017 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 1.2E-21 T 06-07-2017 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 1.2E-21 T 06-07-2017 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 SUPERFAMILY SSF54373 184 281 1.39E-15 T 06-07-2017 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 SUPERFAMILY SSF51905 281 369 4.72E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10340 266945639fc365a500656de2209c7e41 406 SUPERFAMILY SSF51905 11 180 4.72E-61 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 191 206 - T 06-07-2017 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 419 481 2.3E-8 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Pfam PF02885 Glycosyl transferase family, helical bundle domain 93 146 1.0E-11 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Gene3D G3DSA:3.40.1030.10 152 401 1.7E-70 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Hamap MF_00703 Putative thymidine phosphorylase. 1 489 61.598 T 06-07-2017 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Gene3D G3DSA:3.90.1170.30 403 483 1.5E-14 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 PIRSF PIRSF000478 82 488 3.8E-115 T 06-07-2017 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 SUPERFAMILY SSF54680 405 484 2.22E-14 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Pfam PF00591 Glycosyl transferase family, a/b domain 157 385 5.6E-9 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 481 2.3E-171 T 06-07-2017 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 SUPERFAMILY SSF52418 151 401 6.41E-68 T 06-07-2017 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 SUPERFAMILY SSF47648 88 151 7.2E-14 T 06-07-2017 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 SMART SM00941 418 485 2.5E-21 T 06-07-2017 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CAL12_RS24530 648a98b1f4d03961f3dbc81adb105867 489 Gene3D G3DSA:1.20.970.10 89 149 7.3E-13 T 06-07-2017 CAL12_RS18305 330e876a0b10356ba6519ef2bb342e19 303 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS18305 330e876a0b10356ba6519ef2bb342e19 303 Gene3D G3DSA:1.10.600.10 7 299 5.6E-88 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS18305 330e876a0b10356ba6519ef2bb342e19 303 SUPERFAMILY SSF48576 8 282 1.4E-81 T 06-07-2017 IPR008949 Isoprenoid synthase domain CAL12_RS18305 330e876a0b10356ba6519ef2bb342e19 303 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 108 - T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS18305 330e876a0b10356ba6519ef2bb342e19 303 Pfam PF00348 Polyprenyl synthetase 36 268 1.1E-52 T 06-07-2017 IPR000092 Polyprenyl synthetase GO:0008299 CAL12_RS19795 d00bb27d148c6453e31fe3b26ca6fdff 182 SUPERFAMILY SSF52540 4 169 1.71E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19795 d00bb27d148c6453e31fe3b26ca6fdff 182 Pfam PF01202 Shikimate kinase 17 130 5.1E-9 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS19795 d00bb27d148c6453e31fe3b26ca6fdff 182 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 11 165 2.0E-58 T 06-07-2017 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CAL12_RS19795 d00bb27d148c6453e31fe3b26ca6fdff 182 Gene3D G3DSA:3.40.50.300 7 170 9.6E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 SUPERFAMILY SSF54980 399 493 1.01E-26 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 SUPERFAMILY SSF50447 165 288 2.7E-27 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 9.7E-52 T 06-07-2017 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 3.5E-49 T 06-07-2017 IPR013842 GTP-binding protein LepA, C-terminal CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Gene3D G3DSA:3.30.70.870 291 369 4.8E-25 T 06-07-2017 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Pfam PF00679 Elongation factor G C-terminus 399 479 1.5E-22 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 3.8E-297 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 SUPERFAMILY SSF52540 2 205 8.63E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.4E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.4E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.4E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.4E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.4E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 SUPERFAMILY SSF54980 292 370 9.35E-19 T 06-07-2017 IPR009022 Elongation factor G, III-V domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Gene3D G3DSA:3.40.50.300 3 193 8.8E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 300.641 T 06-07-2017 IPR006297 Elongation factor 4 GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 2.4E-19 T 06-07-2017 IPR005225 Small GTP-binding protein domain GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 SMART SM00838 398 486 0.0012 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Gene3D G3DSA:3.30.70.240 401 489 6.0E-22 T 06-07-2017 IPR000640 Translation elongation factor EFG, V domain CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 1.6E-9 T 06-07-2017 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CAL12_RS08405 cd33bab3ac17c37c58075ece33c08099 597 Gene3D G3DSA:2.40.30.10 194 290 4.4E-21 T 06-07-2017 CAL12_RS05290 fe5d02d67e1c5f2ab098c39967794d3b 475 SUPERFAMILY SSF47240 107 332 3.73E-49 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS05290 fe5d02d67e1c5f2ab098c39967794d3b 475 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 4 474 7.9E-269 T 06-07-2017 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00361+1.14.13.20|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CAL12_RS05290 fe5d02d67e1c5f2ab098c39967794d3b 475 Gene3D G3DSA:1.20.1260.10 102 263 2.6E-8 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 SUPERFAMILY SSF90123 34 328 2.62E-28 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 Gene3D G3DSA:1.20.1560.10 65 321 8.6E-20 T 06-07-2017 CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 Pfam PF00664 ABC transporter transmembrane region 148 267 1.6E-11 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 Gene3D G3DSA:3.40.50.300 365 555 1.5E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 Pfam PF00005 ABC transporter 370 519 3.5E-23 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 SMART SM00382 376 562 5.4E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09840 c2f6da8ed9e5fe53c2f61d2edaa3ed65 562 SUPERFAMILY SSF52540 364 557 1.74E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03715 27f34d59a09be05caae65df4821e6555 421 Pfam PF07690 Major Facilitator Superfamily 24 237 1.7E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS03715 27f34d59a09be05caae65df4821e6555 421 Gene3D G3DSA:1.20.1250.20 18 196 1.8E-28 T 06-07-2017 CAL12_RS03715 27f34d59a09be05caae65df4821e6555 421 SUPERFAMILY SSF103473 9 407 1.44E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03715 27f34d59a09be05caae65df4821e6555 421 Gene3D G3DSA:1.20.1250.20 220 405 5.9E-19 T 06-07-2017 CAL12_RS15600 2871942457ed20cc65282b774664b28b 565 Gene3D G3DSA:3.90.1300.10 115 565 1.2E-123 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS15600 2871942457ed20cc65282b774664b28b 565 Pfam PF01425 Amidase 134 556 4.4E-94 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS15600 2871942457ed20cc65282b774664b28b 565 SUPERFAMILY SSF75304 115 565 4.97E-119 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS15600 2871942457ed20cc65282b774664b28b 565 ProSitePatterns PS00571 Amidases signature. 261 292 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 SUPERFAMILY SSF51735 2 247 1.02E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 Gene3D G3DSA:3.40.50.720 2 248 9.3E-74 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 6.9E-55 T 06-07-2017 CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 3.2E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25420 d4a2a02454963fba037d30b2b682fd57 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 210 0.0039 T 06-07-2017 CAL12_RS20315 418064be3afc05e21d205e6ee36d0bce 98 SUPERFAMILY SSF47413 39 84 5.63E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS20315 418064be3afc05e21d205e6ee36d0bce 98 Gene3D G3DSA:1.10.260.40 38 89 9.0E-20 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS20315 418064be3afc05e21d205e6ee36d0bce 98 Pfam PF01381 Helix-turn-helix 39 78 1.8E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS20315 418064be3afc05e21d205e6ee36d0bce 98 SMART SM00530 38 96 3.3E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 Gene3D G3DSA:1.10.3720.10 297 555 8.0E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 268 4.2E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 365 550 2.8E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 Gene3D G3DSA:1.10.3720.10 9 265 6.4E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 SUPERFAMILY SSF161098 295 553 1.7E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04050 33855fb503697d8678083a163da56fbc 583 SUPERFAMILY SSF161098 13 275 5.76E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.2E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 SUPERFAMILY SSF51735 2 214 2.58E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 Gene3D G3DSA:3.40.50.720 6 214 1.3E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16750 bb05cb7584e45252bf96589b3ca916e0 230 Pfam PF00106 short chain dehydrogenase 8 177 1.7E-29 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SMART SM00388 523 590 1.5E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 631 740 1.2E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Gene3D G3DSA:3.30.450.40 139 291 1.1E-10 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SUPERFAMILY SSF55781 136 317 1.72E-54 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SMART SM00065 149 327 2.1E-13 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Gene3D G3DSA:3.30.565.10 590 740 3.0E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Pfam PF00512 His Kinase A (phospho-acceptor) domain 525 588 5.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Pfam PF08446 PAS fold 18 121 3.8E-11 T 06-07-2017 IPR013654 PAS fold-2 GO:0006355 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Gene3D G3DSA:1.10.287.130 515 585 1.1E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SUPERFAMILY SSF47384 510 588 9.42E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SUPERFAMILY SSF55781 325 509 4.58E-51 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SUPERFAMILY SSF55785 10 121 1.67E-18 T 06-07-2017 IPR000014 PAS domain CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Pfam PF01590 GAF domain 151 314 8.6E-20 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SUPERFAMILY SSF55874 597 740 6.29E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 PRINTS PR01033 Phytochrome signature 251 272 3.0E-17 T 06-07-2017 IPR001294 Phytochrome GO:0006355|GO:0009584 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 PRINTS PR01033 Phytochrome signature 349 369 3.0E-17 T 06-07-2017 IPR001294 Phytochrome GO:0006355|GO:0009584 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 PRINTS PR01033 Phytochrome signature 164 183 3.0E-17 T 06-07-2017 IPR001294 Phytochrome GO:0006355|GO:0009584 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 PRINTS PR01033 Phytochrome signature 466 484 3.0E-17 T 06-07-2017 IPR001294 Phytochrome GO:0006355|GO:0009584 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 PRINTS PR01033 Phytochrome signature 434 453 3.0E-17 T 06-07-2017 IPR001294 Phytochrome GO:0006355|GO:0009584 CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 SMART SM00387 631 742 1.1E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS13065 38932bf577bc1bd847d547f4cfef26ee 742 Pfam PF00360 Phytochrome region 329 507 1.6E-53 T 06-07-2017 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 309 334 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 66 92 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 150 173 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 29 56 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 3.4E-71 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 Gene3D G3DSA:3.30.540.10 4 197 8.8E-75 T 06-07-2017 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 196 4.5E-62 T 06-07-2017 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 335 46.875 T 06-07-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PIRSF PIRSF000904 1 339 8.8E-125 T 06-07-2017 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 PIRSF PIRSF500210 1 338 2.0E-127 T 06-07-2017 IPR028343 Fructose-1,6-bisphosphatase GO:0006001|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 SUPERFAMILY SSF56655 3 333 1.83E-116 T 06-07-2017 CAL12_RS17810 b6d79a4d7c959e147fbbcb7e31fd74bd 340 Gene3D G3DSA:3.40.190.80 198 335 1.8E-56 T 06-07-2017 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 SMART SM00434 19 491 3.1E-209 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Gene3D G3DSA:3.30.1360.40 245 361 1.6E-18 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 673 717 0.0036 T 06-07-2017 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 SUPERFAMILY SSF56719 39 513 2.75E-144 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Gene3D G3DSA:2.120.10.90 522 717 6.9E-30 T 06-07-2017 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 40 494 4.1E-123 T 06-07-2017 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Gene3D G3DSA:3.90.199.10 363 428 7.8E-106 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Gene3D G3DSA:3.90.199.10 39 244 7.8E-106 T 06-07-2017 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 SUPERFAMILY SSF101904 528 756 4.58E-46 T 06-07-2017 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 12 767 33.103 T 06-07-2017 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09080 5332a890b90bbeb0b07d9e385aa11d92 769 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 18 753 1.7E-222 T 06-07-2017 CAL12_RS23150 ab510e9b140c38429fdd2cb721cd0251 541 Pfam PF12792 CSS motif domain associated with EAL 43 231 4.4E-29 T 06-07-2017 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain CAL12_RS23150 ab510e9b140c38429fdd2cb721cd0251 541 Pfam PF00563 EAL domain 272 505 5.0E-62 T 06-07-2017 IPR001633 EAL domain CAL12_RS23150 ab510e9b140c38429fdd2cb721cd0251 541 Gene3D G3DSA:3.20.20.450 272 517 6.0E-74 T 06-07-2017 IPR001633 EAL domain CAL12_RS23150 ab510e9b140c38429fdd2cb721cd0251 541 SUPERFAMILY SSF141868 272 517 1.06E-71 T 06-07-2017 IPR001633 EAL domain CAL12_RS23150 ab510e9b140c38429fdd2cb721cd0251 541 SMART SM00052 265 510 3.0E-81 T 06-07-2017 IPR001633 EAL domain CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 SUPERFAMILY SSF52922 487 614 1.96E-32 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 8 614 5.6E-256 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Gene3D G3DSA:3.40.50.970 10 293 2.9E-34 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 278 6.5E-119 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 SMART SM00861 315 479 1.9E-62 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 SUPERFAMILY SSF52518 3 345 4.59E-75 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 616 45.207 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Gene3D G3DSA:3.40.50.920 492 613 1.5E-33 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Gene3D G3DSA:3.40.50.970 294 491 2.4E-68 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 SUPERFAMILY SSF52518 313 499 1.02E-58 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Pfam PF02779 Transketolase, pyrimidine binding domain 314 474 1.2E-37 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 06-07-2017 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS18300 379b56b9311bdbff5d9d4c6ba9c9aeae 629 Pfam PF02780 Transketolase, C-terminal domain 491 607 1.6E-25 T 06-07-2017 IPR033248 Transketolase, C-terminal domain CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 Gene3D G3DSA:3.40.190.10 88 174 8.5E-20 T 06-07-2017 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 SUPERFAMILY SSF53850 88 292 7.78E-35 T 06-07-2017 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 Gene3D G3DSA:1.10.10.10 1 84 5.3E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 Pfam PF03466 LysR substrate binding domain 87 290 2.2E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 SUPERFAMILY SSF46785 1 85 9.67E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 Gene3D G3DSA:3.40.190.10 175 264 2.5E-26 T 06-07-2017 CAL12_RS06815 e58db944ee3deb8e75542912a8513ade 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 60 473 2.8E-121 T 06-07-2017 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 ProSitePatterns PS00543 HlyD family secretion proteins signature. 437 459 - T 06-07-2017 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 112 132 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 452 472 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 339 360 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 372 396 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 437 452 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 396 419 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 70 93 2.2E-47 T 06-07-2017 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 SUPERFAMILY SSF111369 92 222 1.96E-6 T 06-07-2017 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 Pfam PF13437 HlyD family secretion protein 327 435 1.2E-17 T 06-07-2017 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 Gene3D G3DSA:2.40.50.100 104 134 7.5E-15 T 06-07-2017 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 Gene3D G3DSA:2.40.50.100 324 359 7.5E-15 T 06-07-2017 CAL12_RS11470 0006c7138a2fe525a3021ca9667026e5 473 Pfam PF13533 Biotin-lipoyl like 100 140 1.9E-7 T 06-07-2017 CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 189 2.2E-6 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 73 1.2E-17 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 SUPERFAMILY SSF52833 1 84 1.87E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 Gene3D G3DSA:3.40.30.10 1 85 1.4E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 Gene3D G3DSA:1.20.1050.10 86 196 1.2E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS14165 43bbea3b6213c586fe66f7830950fcc9 203 SUPERFAMILY SSF47616 71 195 4.46E-27 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS16685 43063bef67707092b44752311540595c 105 SUPERFAMILY SSF54909 7 100 5.09E-15 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS16685 43063bef67707092b44752311540595c 105 Gene3D G3DSA:3.30.70.900 9 99 4.0E-22 T 06-07-2017 CAL12_RS16685 43063bef67707092b44752311540595c 105 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 9 97 3.0E-12 T 06-07-2017 IPR009799 EthD domain CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 Gene3D G3DSA:1.10.10.10 1 78 4.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 SUPERFAMILY SSF46785 1 84 4.36E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 Pfam PF03466 LysR substrate binding domain 86 278 7.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 SUPERFAMILY SSF53850 87 294 2.44E-31 T 06-07-2017 CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 Gene3D G3DSA:3.40.190.10 192 244 9.0E-12 T 06-07-2017 CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.9E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12725 2c749214b049d1ad240ba1c8c9c14c6e 306 Gene3D G3DSA:3.40.190.10 87 191 8.6E-26 T 06-07-2017 CAL12_RS02535 922d27223f12ff2d3c66fad5666fdf2c 147 SUPERFAMILY SSF55729 4 136 1.31E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02535 922d27223f12ff2d3c66fad5666fdf2c 147 Gene3D G3DSA:3.40.630.30 4 146 4.8E-25 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02535 922d27223f12ff2d3c66fad5666fdf2c 147 Pfam PF00583 Acetyltransferase (GNAT) family 61 131 3.3E-11 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS10675 8483715df9eb552bb6eb0b3b70d3f631 185 SUPERFAMILY SSF52317 6 183 9.51E-46 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS10675 8483715df9eb552bb6eb0b3b70d3f631 185 Pfam PF01965 DJ-1/PfpI family 7 181 3.2E-51 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS10675 8483715df9eb552bb6eb0b3b70d3f631 185 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 9 183 6.9E-42 T 06-07-2017 IPR006286 Peptidase C56, PfpI CAL12_RS10675 8483715df9eb552bb6eb0b3b70d3f631 185 Gene3D G3DSA:3.40.50.880 2 184 1.2E-54 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 Gene3D G3DSA:1.10.10.60 298 344 4.1E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 SUPERFAMILY SSF46689 244 294 3.81E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 Pfam PF12833 Helix-turn-helix domain 266 344 1.9E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 Pfam PF01965 DJ-1/PfpI family 31 204 2.7E-16 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 Gene3D G3DSA:1.10.10.60 250 296 8.5E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 Gene3D G3DSA:3.40.50.880 30 249 8.9E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 SUPERFAMILY SSF52317 30 225 1.06E-44 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 SMART SM00342 260 343 1.3E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS26325 c4b0fb8f8c0ec799719ddec21fe98d04 350 SUPERFAMILY SSF46689 298 345 7.17E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PRINTS PR00981 Seryl-tRNA synthetase signature 300 313 1.5E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PRINTS PR00981 Seryl-tRNA synthetase signature 288 300 1.5E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PRINTS PR00981 Seryl-tRNA synthetase signature 375 391 1.5E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 1.5E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PRINTS PR00981 Seryl-tRNA synthetase signature 340 353 1.5E-30 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 440 7.4E-154 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 Gene3D G3DSA:1.10.287.40 1 104 1.0E-25 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 248 423 4.1E-34 T 06-07-2017 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 445 39.11 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.0E-29 T 06-07-2017 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 SUPERFAMILY SSF46589 1 112 1.94E-30 T 06-07-2017 IPR010978 tRNA-binding arm GO:0000166 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 Gene3D G3DSA:3.30.930.10 105 443 4.0E-135 T 06-07-2017 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 PIRSF PIRSF001529 1 448 7.8E-168 T 06-07-2017 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CAL12_RS21435 5394a455b65128e516932cbf467dc2a6 448 SUPERFAMILY SSF55681 135 443 2.04E-95 T 06-07-2017 CAL12_RS17095 8c8c8854e0dd92d5d56da8a0b3acba6c 269 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 06-07-2017 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CAL12_RS17095 8c8c8854e0dd92d5d56da8a0b3acba6c 269 SUPERFAMILY SSF51556 2 261 7.98E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS17095 8c8c8854e0dd92d5d56da8a0b3acba6c 269 Gene3D G3DSA:3.20.20.140 1 261 6.6E-69 T 06-07-2017 CAL12_RS17095 8c8c8854e0dd92d5d56da8a0b3acba6c 269 Pfam PF01026 TatD related DNase 3 260 3.3E-57 T 06-07-2017 IPR001130 TatD family GO:0016788 CAL12_RS17095 8c8c8854e0dd92d5d56da8a0b3acba6c 269 PIRSF PIRSF005902 1 264 3.8E-54 T 06-07-2017 IPR001130 TatD family GO:0016788 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 121 191 2.6E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 297 371 2.6E-31 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 22 132 6.9E-30 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 174 697 1.5E-132 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 453 597 4.8E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 192 294 5.1E-30 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.90.1170.50 13 120 1.2E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS10360 e667f046148e229396b133ae564b9757 765 SUPERFAMILY SSF54665 12 152 4.19E-40 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 615 760 1.0E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 Gene3D G3DSA:3.30.365.10 374 452 1.0E-50 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 SUPERFAMILY SSF56003 136 760 1.83E-161 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS10360 e667f046148e229396b133ae564b9757 765 SMART SM01008 22 132 9.7E-48 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS12235 c40f8188558d492a8779627653c4ba03 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 2.5E-32 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAL12_RS12235 c40f8188558d492a8779627653c4ba03 144 SUPERFAMILY SSF55961 1 143 3.17E-36 T 06-07-2017 CAL12_RS12235 c40f8188558d492a8779627653c4ba03 144 Gene3D G3DSA:3.30.530.20 1 144 1.9E-46 T 06-07-2017 IPR023393 START-like domain CAL12_RS22540 7b9756437f43b6b7b2e35f020d2fb888 263 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 140 152 - T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAL12_RS22540 7b9756437f43b6b7b2e35f020d2fb888 263 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 261 20.726 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAL12_RS22540 7b9756437f43b6b7b2e35f020d2fb888 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 255 9.3E-85 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAL12_RS22540 7b9756437f43b6b7b2e35f020d2fb888 263 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 261 1.7E-81 T 06-07-2017 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 TIGRFAM TIGR00615 recR: recombination protein RecR 8 200 1.4E-66 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 88.933 T 06-07-2017 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 Pfam PF02132 RecR protein 44 82 2.3E-13 T 06-07-2017 IPR023628 Recombination protein RecR, C4-type zinc finger CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 Pfam PF13662 Toprim domain 84 175 2.5E-21 T 06-07-2017 IPR006171 Toprim domain CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 SUPERFAMILY SSF111304 8 200 2.09E-68 T 06-07-2017 IPR023627 Recombination protein RecR CAL12_RS06475 08045f05ec564c593c9eb7683d70b4db 202 SMART SM00493 84 169 3.0E-8 T 06-07-2017 IPR006171 Toprim domain CAL12_RS13865 320f57c4299dc72b4a89a5e301fc3602 269 Pfam PF12697 Alpha/beta hydrolase family 36 261 2.6E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13865 320f57c4299dc72b4a89a5e301fc3602 269 Gene3D G3DSA:3.40.50.1820 31 268 3.2E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13865 320f57c4299dc72b4a89a5e301fc3602 269 SUPERFAMILY SSF53474 28 266 5.18E-31 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 Pfam PF07559 Flagellar basal body protein FlaE 168 297 2.2E-19 T 06-07-2017 IPR011491 Flagellar hook protein FlgE CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 402 1.3E-90 T 06-07-2017 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 341 418 8.2E-20 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 SUPERFAMILY SSF117143 73 381 1.24E-66 T 06-07-2017 CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 Pfam PF00460 Flagella basal body rod protein 6 33 3.8E-12 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAL12_RS11905 3a7d5b10317b66ba4ea990a03700e02b 420 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 9 29 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAL12_RS15765 a96c1ace4150b688d8a7121dcb756241 284 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 271 40.858 T 06-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CAL12_RS15765 a96c1ace4150b688d8a7121dcb756241 284 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 279 3.5E-73 T 06-07-2017 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 CAL12_RS15765 a96c1ace4150b688d8a7121dcb756241 284 Gene3D G3DSA:3.40.50.150 1 280 4.2E-116 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15765 a96c1ace4150b688d8a7121dcb756241 284 SUPERFAMILY SSF53335 9 280 1.19E-93 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS04705 d6d63d1a4757684e369bae85dd89d085 387 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 111 382 1.3E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04705 d6d63d1a4757684e369bae85dd89d085 387 SUPERFAMILY SSF53850 176 348 1.95E-11 T 06-07-2017 CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 Gene3D G3DSA:3.40.50.720 1 178 2.2E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 170 293 7.9E-34 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 149 1.9E-38 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 SUPERFAMILY SSF51735 1 159 4.13E-20 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 SUPERFAMILY SSF48179 170 293 1.16E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 294 2.5E-82 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS23100 b3e7cff26de55d9986944f7620a48d7c 296 Gene3D G3DSA:1.10.1040.10 179 294 1.1E-38 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SUPERFAMILY SSF52540 201 453 1.86E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 460 5.1E-151 T 06-07-2017 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Gene3D G3DSA:1.10.150.80 538 606 3.3E-16 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 8 604 2.8E-239 T 06-07-2017 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Gene3D G3DSA:1.10.10.10 339 514 2.2E-58 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Gene3D G3DSA:3.40.50.300 4 197 2.1E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SUPERFAMILY SSF52540 3 189 2.03E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SUPERFAMILY SSF47819 531 607 4.8E-23 T 06-07-2017 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SMART SM00956 405 512 8.1E-53 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Pfam PF00570 HRDC domain 539 604 1.4E-22 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Pfam PF16124 RecQ zinc-binding 337 398 1.8E-16 T 06-07-2017 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SMART SM00341 534 608 8.1E-11 T 06-07-2017 IPR002121 HRDC domain GO:0003676|GO:0005622 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SMART SM00490 244 325 5.5E-23 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Gene3D G3DSA:3.40.50.300 200 338 1.3E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Pfam PF00270 DEAD/DEAH box helicase 23 178 7.3E-16 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 SMART SM00487 15 211 2.6E-27 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Pfam PF09382 RQC domain 400 514 1.9E-39 T 06-07-2017 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CAL12_RS05555 821089026d639dc3a9f35cf13b3fd0ab 608 Pfam PF00271 Helicase conserved C-terminal domain 218 325 1.7E-14 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS00550 2934c21192f183d033f1d6b7d351bcaa 369 Gene3D G3DSA:3.60.15.10 16 299 5.0E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS00550 2934c21192f183d033f1d6b7d351bcaa 369 SUPERFAMILY SSF56281 22 347 2.44E-70 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS00550 2934c21192f183d033f1d6b7d351bcaa 369 SMART SM00849 42 269 9.5E-22 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS00550 2934c21192f183d033f1d6b7d351bcaa 369 Pfam PF00753 Metallo-beta-lactamase superfamily 42 269 1.8E-24 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS08635 9556a947f72d19e3fa3a88fefa3e68b7 272 PIRSF PIRSF015853 1 272 2.1E-103 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAL12_RS08635 9556a947f72d19e3fa3a88fefa3e68b7 272 Pfam PF04951 D-aminopeptidase 1 262 1.1E-98 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAL12_RS08635 9556a947f72d19e3fa3a88fefa3e68b7 272 Gene3D G3DSA:3.40.50.10780 1 211 3.0E-79 T 06-07-2017 IPR027476 D-aminopeptidase, N-terminal CAL12_RS08635 9556a947f72d19e3fa3a88fefa3e68b7 272 SUPERFAMILY SSF63992 1 272 1.57E-103 T 06-07-2017 IPR007035 Peptidase M55, D-aminopeptidase CAL12_RS13050 14d3174a15481741bf7f5bedc310b268 194 Gene3D G3DSA:1.20.910.10 2 191 8.9E-43 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS13050 14d3174a15481741bf7f5bedc310b268 194 Pfam PF01126 Heme oxygenase 3 186 3.0E-7 T 06-07-2017 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS13050 14d3174a15481741bf7f5bedc310b268 194 SUPERFAMILY SSF48613 3 186 2.07E-31 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS09325 882c5f70548033608827277f030cc253 93 TIGRFAM TIGR03510 XapX: XapX domain 4 49 2.9E-19 T 06-07-2017 IPR020017 XapX domain CAL12_RS09325 882c5f70548033608827277f030cc253 93 Pfam PF07235 Protein of unknown function (DUF1427) 2 81 1.0E-37 T 06-07-2017 IPR009872 Protein of unknown function DUF1427 CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 SUPERFAMILY SSF51126 2 122 1.73E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 9 37 1.9E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 92 121 2.2E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 Pfam PF12951 Passenger-associated-transport-repeat 8 36 1.6E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 Pfam PF12951 Passenger-associated-transport-repeat 93 122 4.9E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23660 fbe749de90691f2590cbc1e193e6d2c4 122 Gene3D G3DSA:2.160.20.20 1 122 3.4E-19 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Pfam PF00231 ATP synthase 4 298 1.8E-85 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 299 34.629 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Gene3D G3DSA:1.10.287.80 19 60 2.5E-39 T 06-07-2017 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Gene3D G3DSA:1.10.287.80 214 247 2.5E-39 T 06-07-2017 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 PRINTS PR00126 ATP synthase gamma subunit signature 246 265 2.9E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 2.9E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 2.9E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 PRINTS PR00126 ATP synthase gamma subunit signature 277 298 2.9E-34 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 285 298 - T 06-07-2017 IPR023632 ATPase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Gene3D G3DSA:1.10.287.80 248 294 4.5E-29 T 06-07-2017 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 Gene3D G3DSA:3.40.1380.10 64 192 2.9E-34 T 06-07-2017 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 299 1.6E-97 T 06-07-2017 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25800 87870ea0d6cabba0522dac57e6d4b5df 299 SUPERFAMILY SSF52943 3 299 1.57E-89 T 06-07-2017 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 CAL12_RS06405 b637887820669d1b955194177d4082b1 212 Pfam PF09335 SNARE associated Golgi protein 46 170 1.8E-20 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAL12_RS13940 f4a2a1e9bdfa384d5f465fa8dba897a3 271 Gene3D G3DSA:1.10.230.10 122 212 2.4E-9 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS13940 f4a2a1e9bdfa384d5f465fa8dba897a3 271 Gene3D G3DSA:1.10.580.10 38 121 5.5E-9 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS13940 f4a2a1e9bdfa384d5f465fa8dba897a3 271 Pfam PF00285 Citrate synthase, C-terminal domain 42 243 2.3E-27 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS13940 f4a2a1e9bdfa384d5f465fa8dba897a3 271 SUPERFAMILY SSF48256 30 245 3.79E-41 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS21220 7782a914eb134cc76f959f9bdc604d8d 463 Gene3D G3DSA:3.40.605.10 2 244 6.5E-77 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS21220 7782a914eb134cc76f959f9bdc604d8d 463 SUPERFAMILY SSF53720 2 454 4.19E-137 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS21220 7782a914eb134cc76f959f9bdc604d8d 463 Pfam PF00171 Aldehyde dehydrogenase family 3 452 8.5E-136 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS21220 7782a914eb134cc76f959f9bdc604d8d 463 Gene3D G3DSA:3.40.309.10 245 429 1.9E-54 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS04415 e501138278f6ed65ee1cee15d3ae9dfd 425 Gene3D G3DSA:2.60.120.600 259 423 5.0E-45 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS04415 e501138278f6ed65ee1cee15d3ae9dfd 425 Gene3D G3DSA:2.60.40.1610 72 187 3.0E-22 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS04415 e501138278f6ed65ee1cee15d3ae9dfd 425 Pfam PF06742 Protein of unknown function (DUF1214) 300 408 1.6E-33 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS04415 e501138278f6ed65ee1cee15d3ae9dfd 425 SUPERFAMILY SSF160935 10 423 1.31E-99 T 06-07-2017 CAL12_RS04415 e501138278f6ed65ee1cee15d3ae9dfd 425 Pfam PF06863 Protein of unknown function (DUF1254) 60 188 4.2E-47 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS26515 ad559ddd76aeec5a84438c3c9e3d1003 179 Gene3D G3DSA:3.10.180.10 7 145 1.3E-15 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS26515 ad559ddd76aeec5a84438c3c9e3d1003 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 6.8E-30 T 06-07-2017 CAL12_RS26515 ad559ddd76aeec5a84438c3c9e3d1003 179 SUPERFAMILY SSF54593 10 146 1.59E-16 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 195 5.9E-38 T 06-07-2017 CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 197 7.6E-20 T 06-07-2017 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 Gene3D G3DSA:3.40.50.1000 85 224 1.0E-51 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 Gene3D G3DSA:1.20.1440.100 18 84 2.7E-23 T 06-07-2017 CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 6 208 3.6E-36 T 06-07-2017 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial CAL12_RS06380 616e848cedee940be5f8b1969f0d0691 232 SUPERFAMILY SSF56784 5 220 3.99E-31 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS24465 fbb7235aa2a9f6ff9c8b3216c16d3207 157 Gene3D G3DSA:2.60.120.10 23 129 5.7E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS24465 fbb7235aa2a9f6ff9c8b3216c16d3207 157 SUPERFAMILY SSF51182 28 139 1.81E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS24465 fbb7235aa2a9f6ff9c8b3216c16d3207 157 Pfam PF07883 Cupin domain 43 111 4.4E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 251 257 - T 06-07-2017 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Gene3D G3DSA:1.10.10.60 9 64 2.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 202 280 5.4E-30 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 SUPERFAMILY SSF46689 14 60 1.43E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Pfam PF12833 Helix-turn-helix domain 33 114 1.1E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 SUPERFAMILY SSF46767 200 281 3.27E-29 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 SMART SM00342 27 113 4.2E-22 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Gene3D G3DSA:1.10.10.10 200 281 3.3E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Gene3D G3DSA:1.10.10.60 65 111 2.2E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 SUPERFAMILY SSF53155 119 199 4.71E-21 T 06-07-2017 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 Gene3D G3DSA:3.30.160.70 112 199 1.1E-35 T 06-07-2017 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 64 109 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS12205 a84f5862da402989e3fcb278f313f443 285 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 201 280 3.7E-33 T 06-07-2017 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 06-07-2017 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 255 53.237 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 253 1.6E-79 T 06-07-2017 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 SMART SM00650 20 188 5.2E-75 T 06-07-2017 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 Gene3D G3DSA:1.10.8.100 195 255 7.3E-19 T 06-07-2017 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 252 2.9E-54 T 06-07-2017 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 Gene3D G3DSA:3.40.50.150 2 187 2.6E-65 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS06300 fbe740cb41b0468ec9e5bac0a563474a 272 SUPERFAMILY SSF53335 4 256 1.15E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 Gene3D G3DSA:3.10.290.10 11 59 1.2E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 298 1.9E-78 T 06-07-2017 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 SUPERFAMILY SSF55174 10 62 1.47E-8 T 06-07-2017 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 SUPERFAMILY SSF55120 74 299 2.4E-64 T 06-07-2017 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 Pfam PF00849 RNA pseudouridylate synthase 87 235 4.7E-29 T 06-07-2017 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 125 139 - T 06-07-2017 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 Pfam PF01479 S4 domain 11 57 1.6E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS08305 d701a4391ce6ce588d41206c4a9059cb 301 SMART SM00363 11 70 6.8E-7 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS10580 9e937b9ee5097c1c52bdc814c1359b5a 276 Gene3D G3DSA:3.40.50.300 16 234 1.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10580 9e937b9ee5097c1c52bdc814c1359b5a 276 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10580 9e937b9ee5097c1c52bdc814c1359b5a 276 SUPERFAMILY SSF52540 22 248 6.41E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10580 9e937b9ee5097c1c52bdc814c1359b5a 276 SMART SM00382 52 244 1.5E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10580 9e937b9ee5097c1c52bdc814c1359b5a 276 Pfam PF00005 ABC transporter 43 181 3.5E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS11230 355525abbb5de3c6cd61eeab493703f0 210 SUPERFAMILY SSF51182 6 175 2.67E-51 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS11230 355525abbb5de3c6cd61eeab493703f0 210 Gene3D G3DSA:2.60.120.10 109 154 5.2E-4 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS11230 355525abbb5de3c6cd61eeab493703f0 210 Gene3D G3DSA:2.60.120.10 9 108 6.0E-37 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS11230 355525abbb5de3c6cd61eeab493703f0 210 Pfam PF05962 HutD 9 179 3.5E-54 T 06-07-2017 IPR010282 Uncharacterised protein family HutD/Ves CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SUPERFAMILY SSF47336 596 667 6.67E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 1234 1519 3.4E-44 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:3.60.130.10 1217 1369 1.2E-52 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:3.60.130.10 1401 1522 1.2E-52 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SUPERFAMILY SSF52777 719 892 1.22E-42 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:3.40.50.980 187 350 5.7E-37 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SMART SM00823 Phosphopantetheine attachment site 601 670 7.1E-4 T 06-07-2017 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SUPERFAMILY SSF52777 899 1139 3.34E-50 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Pfam PF00550 Phosphopantetheine attachment site 603 666 2.8E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Pfam PF00501 AMP-binding enzyme 18 466 8.3E-88 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:3.40.50.980 10 186 2.0E-32 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SUPERFAMILY SSF56801 10 575 1.27E-113 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Pfam PF00668 Condensation domain 718 1009 1.6E-64 T 06-07-2017 IPR001242 Condensation domain CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:1.10.1200.10 595 671 1.9E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:2.30.38.10 380 455 4.8E-20 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Pfam PF13745 HxxPF-repeated domain 1032 1122 1.6E-22 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 SUPERFAMILY SSF51197 1211 1520 8.7E-76 T 06-07-2017 CAL12_RS11040 32fc3102fd8cf81f17f0c8e649b3a564 1534 Gene3D G3DSA:3.30.300.30 457 565 2.8E-14 T 06-07-2017 CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 257 334 8.9E-11 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 SUPERFAMILY SSF52540 3 184 1.59E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 SUPERFAMILY SSF90002 247 335 6.15E-13 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 Gene3D G3DSA:3.40.50.300 3 193 5.5E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 185 3.7E-42 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 Gene3D G3DSA:3.30.1220.10 243 335 5.1E-13 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS18460 f835514a57b00caa51893b1ffc129d9f 343 SMART SM00833 242 336 3.6E-6 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS26010 ef10e611b431d71d2824420c68f3980b 159 Pfam PF03928 Haem-degrading 7 137 1.6E-26 T 06-07-2017 IPR005624 Haem-degrading CAL12_RS26010 ef10e611b431d71d2824420c68f3980b 159 SUPERFAMILY SSF143744 2 140 7.72E-35 T 06-07-2017 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 ProSitePatterns PS01344 Frataxin family signature. 52 66 - T 06-07-2017 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 SUPERFAMILY SSF55387 1 105 9.24E-30 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 Hamap MF_00142 Protein CyaY [cyaY]. 1 107 24.111 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 106 4.4E-35 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 Pfam PF01491 Frataxin-like domain 1 103 6.5E-23 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 Gene3D G3DSA:3.30.920.10 1 105 4.1E-27 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS27440 05882299d86abfb67ca6915084ff291a 109 SMART SM01219 1 108 1.8E-42 T 06-07-2017 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 Gene3D G3DSA:3.40.50.9100 15 156 5.4E-55 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 162 58.718 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 Pfam PF01220 Dehydroquinase class II 16 152 3.3E-49 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 SUPERFAMILY SSF52304 16 158 2.62E-50 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 153 2.0E-37 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS14440 c42d583e6b2024fbdab5bdb0a92c59a3 162 PIRSF PIRSF001399 13 158 8.9E-52 T 06-07-2017 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS21575 c5338e3b1e04d85083c9f225c00720d2 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 7 29 5.0E-9 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAL12_RS21575 c5338e3b1e04d85083c9f225c00720d2 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 7 29 1.7E-9 T 06-07-2017 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SUPERFAMILY SSF47384 499 582 1.02E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SMART SM00387 634 751 4.0E-31 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Gene3D G3DSA:3.30.565.10 588 747 5.6E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SMART SM00304 315 367 9.8E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Pfam PF13188 PAS domain 382 441 1.2E-4 T 06-07-2017 IPR000014 PAS domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SMART SM00388 513 585 1.5E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Pfam PF00672 HAMP domain 297 363 5.9E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Gene3D G3DSA:3.30.450.20 373 504 3.2E-11 T 06-07-2017 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SUPERFAMILY SSF158472 316 364 1.28E-6 T 06-07-2017 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 700 710 4.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 682 696 4.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 729 4.1E-12 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 634 747 1.2E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SUPERFAMILY SSF55874 574 747 3.89E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 SUPERFAMILY SSF55785 373 503 1.9E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Pfam PF00512 His Kinase A (phospho-acceptor) domain 514 581 6.7E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 Gene3D G3DSA:1.10.287.130 514 581 3.0E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26260 da255fc5b1343bdb24933127ac3708a6 770 PIRSF PIRSF037532 1 752 4.1E-235 T 06-07-2017 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 46.751 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 SUPERFAMILY SSF55205 1 417 5.23E-140 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.1E-178 T 06-07-2017 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 Gene3D G3DSA:3.65.10.10 21 220 2.4E-67 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 2.6E-104 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS00850 3a2b5953eae22b3b5972db4a31c3d1bc 422 Gene3D G3DSA:3.65.10.10 221 416 3.0E-59 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 SUPERFAMILY SSF48498 63 177 7.07E-23 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 42 3.2E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 Gene3D G3DSA:1.10.357.10 50 181 3.2E-39 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 Gene3D G3DSA:1.10.10.60 1 48 3.6E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 8 38 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS09860 0a4b2e7be3361cdaea898b8016555a23 206 SUPERFAMILY SSF46689 1 61 4.26E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS19065 c1be4686b1fa92c5803996386a05d898 229 Pfam PF01584 CheW-like domain 88 223 1.8E-24 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS19065 c1be4686b1fa92c5803996386a05d898 229 SUPERFAMILY SSF50341 80 223 3.53E-29 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS19065 c1be4686b1fa92c5803996386a05d898 229 SMART SM00260 83 221 1.3E-11 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS24500 70a848101bdc3f72ef6da79770018a42 328 Pfam PF09084 NMT1/THI5 like 39 243 2.0E-33 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS24500 70a848101bdc3f72ef6da79770018a42 328 SUPERFAMILY SSF53850 33 252 2.96E-23 T 06-07-2017 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 Pfam PF00034 Cytochrome c 147 216 1.2E-8 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 PIRSF PIRSF000005 1 218 1.8E-64 T 06-07-2017 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 SUPERFAMILY SSF46626 147 236 6.73E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 SUPERFAMILY SSF46626 23 112 6.73E-19 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 44 108 8.5E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 Gene3D G3DSA:1.10.760.10 126 217 1.6E-21 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS01695 b550b2466d68fc161cc0aa5b86b616dc 240 Gene3D G3DSA:1.10.760.10 25 112 9.3E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS10180 a7ba6e2b9d864f024f10ca02ff0ad3a6 249 Pfam PF00535 Glycosyl transferase family 2 7 123 1.9E-18 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS10180 a7ba6e2b9d864f024f10ca02ff0ad3a6 249 Gene3D G3DSA:3.90.550.10 9 118 1.4E-11 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS10180 a7ba6e2b9d864f024f10ca02ff0ad3a6 249 SUPERFAMILY SSF53448 4 232 1.97E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS16650 fc2aa30fd9586745dc6f498bbbdd98f0 219 Gene3D G3DSA:1.10.357.10 14 208 1.5E-31 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16650 fc2aa30fd9586745dc6f498bbbdd98f0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16650 fc2aa30fd9586745dc6f498bbbdd98f0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.4E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16650 fc2aa30fd9586745dc6f498bbbdd98f0 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 9.9E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16650 fc2aa30fd9586745dc6f498bbbdd98f0 219 SUPERFAMILY SSF46689 15 89 4.99E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12345 1cef922ba9e7d5b617c2e9b9689ccd1a 129 Pfam PF04241 Protein of unknown function (DUF423) 20 108 8.7E-30 T 06-07-2017 IPR006696 Protein of unknown function DUF423 CAL12_RS17780 3944a731acd158aa17be7ff4851ef8ab 356 Gene3D G3DSA:3.20.20.70 9 350 5.6E-156 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS17780 3944a731acd158aa17be7ff4851ef8ab 356 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 1.4E-163 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAL12_RS17780 3944a731acd158aa17be7ff4851ef8ab 356 Pfam PF00793 DAHP synthetase I family 41 338 2.7E-102 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS17780 3944a731acd158aa17be7ff4851ef8ab 356 SUPERFAMILY SSF51569 7 348 6.59E-138 T 06-07-2017 CAL12_RS17780 3944a731acd158aa17be7ff4851ef8ab 356 PIRSF PIRSF001361 1 352 1.1E-159 T 06-07-2017 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CAL12_RS09670 b60e31a65a2f372f4482cfd1a042fe2f 216 SUPERFAMILY SSF52016 1 201 2.16E-60 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS09670 b60e31a65a2f372f4482cfd1a042fe2f 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 42.769 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS09670 b60e31a65a2f372f4482cfd1a042fe2f 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 7.9E-79 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS09670 b60e31a65a2f372f4482cfd1a042fe2f 216 Gene3D G3DSA:3.20.19.10 1 204 1.3E-49 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS09670 b60e31a65a2f372f4482cfd1a042fe2f 216 Pfam PF00694 Aconitase C-terminal domain 1 132 1.1E-36 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS23190 14540c09e5e8bc37a094557e5b5bef28 232 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23190 14540c09e5e8bc37a094557e5b5bef28 232 Pfam PF00005 ABC transporter 18 158 7.6E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23190 14540c09e5e8bc37a094557e5b5bef28 232 SMART SM00382 27 207 8.6E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23190 14540c09e5e8bc37a094557e5b5bef28 232 Gene3D G3DSA:3.40.50.300 3 225 5.1E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23190 14540c09e5e8bc37a094557e5b5bef28 232 SUPERFAMILY SSF52540 3 223 2.81E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 SUPERFAMILY SSF47616 105 227 7.38E-32 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 Pfam PF00043 Glutathione S-transferase, C-terminal domain 140 220 5.0E-9 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 Gene3D G3DSA:3.40.30.10 19 105 8.2E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 SUPERFAMILY SSF52833 9 100 2.29E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 Pfam PF02798 Glutathione S-transferase, N-terminal domain 19 96 2.1E-12 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS25170 5e992fcf42b9ebf967214ffd8fa8596b 231 Gene3D G3DSA:1.20.1050.10 106 224 5.4E-40 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19015 65fe3f8ac2b48b13e460b87c0ffceb0c 391 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 9 386 1.1E-126 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAL12_RS23815 961442057569ffefc9eb6ff1871720bf 335 SUPERFAMILY SSF53850 123 300 1.21E-12 T 06-07-2017 CAL12_RS23815 961442057569ffefc9eb6ff1871720bf 335 PIRSF PIRSF017082 4 334 1.9E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23815 961442057569ffefc9eb6ff1871720bf 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 62 331 2.2E-63 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23815 961442057569ffefc9eb6ff1871720bf 335 Gene3D G3DSA:3.40.190.10 139 221 3.4E-4 T 06-07-2017 CAL12_RS26830 cfbeacbe3038d4160bdbdc689bbcfb3d 378 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 161 374 1.3E-66 T 06-07-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CAL12_RS26830 cfbeacbe3038d4160bdbdc689bbcfb3d 378 Pfam PF02405 Permease MlaE 162 371 2.2E-67 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAL12_RS00865 418f4533b7b9ec573c03e93984edc9c1 265 Pfam PF00005 ABC transporter 35 177 3.5E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00865 418f4533b7b9ec573c03e93984edc9c1 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00865 418f4533b7b9ec573c03e93984edc9c1 265 SMART SM00382 44 224 2.1E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00865 418f4533b7b9ec573c03e93984edc9c1 265 Gene3D G3DSA:3.40.50.300 3 238 7.0E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00865 418f4533b7b9ec573c03e93984edc9c1 265 SUPERFAMILY SSF52540 30 239 1.43E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05155 03740b5b589e3430d2f3ef88d335a453 305 Pfam PF06007 Phosphonate metabolism protein PhnJ 21 291 2.3E-146 T 06-07-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 CAL12_RS05155 03740b5b589e3430d2f3ef88d335a453 305 PIRSF PIRSF011468 12 302 3.6E-158 T 06-07-2017 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399 CAL12_RS15875 5ed383f825d2c2a84299bd5fed3e3054 194 Pfam PF04345 Chorismate lyase 23 188 3.4E-16 T 06-07-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 CAL12_RS15875 5ed383f825d2c2a84299bd5fed3e3054 194 SUPERFAMILY SSF64288 10 185 8.57E-40 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS15875 5ed383f825d2c2a84299bd5fed3e3054 194 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 9 187 23.263 T 06-07-2017 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148 CAL12_RS15875 5ed383f825d2c2a84299bd5fed3e3054 194 Gene3D G3DSA:3.40.1410.10 11 185 4.6E-42 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 SMART SM00866 116 257 5.6E-14 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 95 2.0E-20 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 Gene3D G3DSA:1.10.10.10 27 97 2.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 Gene3D G3DSA:3.40.1410.10 119 261 1.2E-22 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 SMART SM00345 36 95 3.3E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 SUPERFAMILY SSF46785 29 99 5.12E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 3.4E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 3.4E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 SUPERFAMILY SSF64288 83 263 5.81E-27 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS07075 56e688c315b0a0bbb5368f7c40f28616 265 Pfam PF07702 UTRA domain 126 257 2.5E-14 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 SUPERFAMILY SSF51126 130 317 1.82E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 6 37 1.5E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 289 318 3.4E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 Gene3D G3DSA:2.160.20.20 2 317 2.5E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 SUPERFAMILY SSF51126 2 129 1.48E-13 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 Pfam PF12951 Passenger-associated-transport-repeat 290 318 4.7E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23680 4c95d68e8e1ea0565c25c618151dcd55 318 Pfam PF12951 Passenger-associated-transport-repeat 7 36 7.7E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 Gene3D G3DSA:3.30.450.20 145 200 1.0E-4 T 06-07-2017 CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 53 82 4.6E-10 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 24 51 4.6E-10 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 Gene3D G3DSA:1.10.287.950 4 109 7.7E-20 T 06-07-2017 CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 5 88 1.2E-13 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS00500 1671aa393a09e66991b5d84d0bf34da0 337 SUPERFAMILY SSF58104 5 108 2.09E-19 T 06-07-2017 CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 PIRSF PIRSF002094 19 185 9.0E-49 T 06-07-2017 IPR005632 Chaperone protein Skp GO:0051082 CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 Gene3D G3DSA:3.30.910.20 34 81 9.7E-35 T 06-07-2017 CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 Gene3D G3DSA:3.30.910.20 119 183 9.7E-35 T 06-07-2017 CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 Pfam PF03938 Outer membrane protein (OmpH-like) 30 183 5.0E-35 T 06-07-2017 IPR005632 Chaperone protein Skp GO:0051082 CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 SUPERFAMILY SSF111384 43 183 1.14E-34 T 06-07-2017 IPR024930 Skp domain CAL12_RS12160 fd474d28b95605c34a3efe7c57dfc7bd 185 SMART SM00935 32 184 2.8E-55 T 06-07-2017 IPR005632 Chaperone protein Skp GO:0051082 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 9.0E-38 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 387 1.6E-37 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Gene3D G3DSA:1.10.540.10 4 124 7.4E-44 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 2.9E-27 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 SUPERFAMILY SSF47203 232 390 1.93E-43 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 SUPERFAMILY SSF56645 6 247 8.51E-88 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Gene3D G3DSA:1.20.140.10 222 390 1.2E-59 T 06-07-2017 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 06-07-2017 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CAL12_RS00540 32f69b4188b3ea03c00f4ea0944927bb 392 Gene3D G3DSA:2.40.110.10 126 221 5.8E-42 T 06-07-2017 CAL12_RS07070 1b0eb5bbe9f168fb0d8f10707b12f6a9 347 SUPERFAMILY SSF53474 36 343 1.05E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS07070 1b0eb5bbe9f168fb0d8f10707b12f6a9 347 Gene3D G3DSA:3.40.50.1820 30 345 2.4E-98 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24720 a0889f325a8ab85fd901736e92e6b737 419 Gene3D G3DSA:2.70.70.10 232 370 1.6E-45 T 06-07-2017 CAL12_RS24720 a0889f325a8ab85fd901736e92e6b737 419 Pfam PF01551 Peptidase family M23 272 368 3.6E-32 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS24720 a0889f325a8ab85fd901736e92e6b737 419 SUPERFAMILY SSF51261 121 370 6.28E-72 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 9.3E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 Gene3D G3DSA:3.40.190.10 92 176 3.2E-21 T 06-07-2017 CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 SUPERFAMILY SSF53850 90 297 3.04E-42 T 06-07-2017 CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 SUPERFAMILY SSF46785 2 112 2.63E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 Gene3D G3DSA:1.10.10.10 3 88 9.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 Pfam PF03466 LysR substrate binding domain 89 293 1.7E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS00065 1a8b583a76c5c7bb1bd0c488a7280797 309 Gene3D G3DSA:3.40.190.10 177 265 3.0E-18 T 06-07-2017 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Gene3D G3DSA:3.50.50.60 173 251 8.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Gene3D G3DSA:3.50.50.60 342 400 8.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Gene3D G3DSA:3.50.50.60 21 111 8.0E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 3 406 8.4E-209 T 06-07-2017 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Pfam PF01266 FAD dependent oxidoreductase 34 378 1.0E-54 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 SUPERFAMILY SSF51905 32 252 5.06E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 SUPERFAMILY SSF51905 342 402 5.06E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Gene3D G3DSA:3.30.9.10 116 172 3.5E-10 T 06-07-2017 CAL12_RS06120 97a723a2dcc228f46d070ec4d5b046b0 414 Gene3D G3DSA:3.30.9.10 252 339 3.5E-10 T 06-07-2017 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 SUPERFAMILY SSF46894 250 316 3.2E-18 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 274 290 1.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 290 302 1.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 260 274 1.5E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 SUPERFAMILY SSF52172 6 132 2.42E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 Gene3D G3DSA:3.40.50.2300 8 131 2.0E-38 T 06-07-2017 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 Pfam PF00072 Response regulator receiver domain 10 121 9.9E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 Pfam PF00196 Bacterial regulatory proteins, luxR family 259 313 7.0E-18 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 SMART SM00421 257 314 1.2E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 Gene3D G3DSA:1.10.10.10 259 316 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 SMART SM00448 8 121 2.4E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS03780 3b9da7c8657cd2db4a20862ca92faaad 322 ProSitePatterns PS00622 LuxR-type HTH domain signature. 274 301 - T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS06045 341cf78efa0b695c459be256d10729d4 414 SUPERFAMILY SSF89796 18 410 6.15E-128 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06045 341cf78efa0b695c459be256d10729d4 414 Pfam PF02515 CoA-transferase family III 20 386 5.4E-122 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS06045 341cf78efa0b695c459be256d10729d4 414 Gene3D G3DSA:3.40.50.10540 17 230 7.8E-110 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06045 341cf78efa0b695c459be256d10729d4 414 Gene3D G3DSA:3.40.50.10540 320 411 7.8E-110 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06045 341cf78efa0b695c459be256d10729d4 414 Gene3D G3DSA:3.30.1540.10 236 319 2.9E-25 T 06-07-2017 CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 SUPERFAMILY SSF46785 1 84 8.16E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 Pfam PF03466 LysR substrate binding domain 85 285 1.5E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 5.6E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 Gene3D G3DSA:1.10.10.10 1 83 5.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 SUPERFAMILY SSF53850 86 287 2.17E-37 T 06-07-2017 CAL12_RS04675 e32bb7e0e1c0aaa3442549b79a5bb54e 295 Gene3D G3DSA:3.40.190.10 86 221 1.1E-26 T 06-07-2017 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 SUPERFAMILY SSF100950 2 221 8.37E-78 T 06-07-2017 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 06-07-2017 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 SMART SM00882 6 219 1.1E-82 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 1.9E-112 T 06-07-2017 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 Gene3D G3DSA:3.40.1080.10 4 218 2.3E-86 T 06-07-2017 CAL12_RS01855 de3b32aedb12a9e2af1f87d340f2bc87 225 Pfam PF01144 Coenzyme A transferase 6 218 2.8E-68 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS22660 3fb0912565f965ab01cabe6d9f5e5486 277 SUPERFAMILY SSF52540 10 234 4.11E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22660 3fb0912565f965ab01cabe6d9f5e5486 277 Pfam PF00005 ABC transporter 33 172 5.8E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22660 3fb0912565f965ab01cabe6d9f5e5486 277 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS22660 3fb0912565f965ab01cabe6d9f5e5486 277 SMART SM00382 35 223 2.8E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22660 3fb0912565f965ab01cabe6d9f5e5486 277 Gene3D G3DSA:3.40.50.300 10 235 1.7E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06820 6e3fd8184d066169ecc0ebaf74fec594 331 SUPERFAMILY SSF53850 118 284 1.04E-13 T 06-07-2017 CAL12_RS06820 6e3fd8184d066169ecc0ebaf74fec594 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 1.8E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06820 6e3fd8184d066169ecc0ebaf74fec594 331 PIRSF PIRSF017082 1 330 2.1E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16835 825a3d8c2caf20f39afaad6b58009d21 166 Pfam PF02464 Competence-damaged protein 7 157 1.8E-35 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS16835 825a3d8c2caf20f39afaad6b58009d21 166 Gene3D G3DSA:3.90.950.20 3 159 2.4E-39 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS16835 825a3d8c2caf20f39afaad6b58009d21 166 SUPERFAMILY SSF142433 4 158 3.53E-36 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS18060 6d5d8832cdc3615b5e0a8e4a19fbc313 303 Gene3D G3DSA:1.10.3720.10 11 288 2.0E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18060 6d5d8832cdc3615b5e0a8e4a19fbc313 303 SUPERFAMILY SSF161098 11 289 3.01E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18060 6d5d8832cdc3615b5e0a8e4a19fbc313 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 284 2.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 Pfam PF06826 Predicted Permease Membrane Region 17 183 3.1E-35 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 Pfam PF06826 Predicted Permease Membrane Region 393 560 3.6E-32 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 Pfam PF02080 TrkA-C domain 220 283 5.9E-7 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 SUPERFAMILY SSF116726 295 379 4.32E-7 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 SUPERFAMILY SSF116726 217 293 4.05E-8 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 396 546 7.0E-25 T 06-07-2017 IPR006512 YidE/YbjL duplication CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 Gene3D G3DSA:3.30.70.1450 221 286 4.2E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS22260 57b5e2893563da162b184cc81929e18e 565 Gene3D G3DSA:3.30.70.1450 309 378 2.5E-5 T 06-07-2017 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CAL12_RS18750 496e7c0175a3ee950234e39b38739c6c 313 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 24 278 3.2E-92 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAL12_RS18750 496e7c0175a3ee950234e39b38739c6c 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 271 2.8E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18750 496e7c0175a3ee950234e39b38739c6c 313 SUPERFAMILY SSF161098 22 271 5.49E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18750 496e7c0175a3ee950234e39b38739c6c 313 Gene3D G3DSA:1.10.3720.10 25 278 7.4E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18750 496e7c0175a3ee950234e39b38739c6c 313 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 22 280 1.3E-119 T 06-07-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CAL12_RS15815 3a7f52eecbf7d08421c2f1c6f0adbf9b 203 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 188 37.8 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS15815 3a7f52eecbf7d08421c2f1c6f0adbf9b 203 SUPERFAMILY SSF52507 3 186 1.44E-63 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS15815 3a7f52eecbf7d08421c2f1c6f0adbf9b 203 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 4 186 2.2E-73 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS15815 3a7f52eecbf7d08421c2f1c6f0adbf9b 203 Pfam PF02441 Flavoprotein 4 131 3.4E-25 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS15815 3a7f52eecbf7d08421c2f1c6f0adbf9b 203 Gene3D G3DSA:3.40.50.1950 3 188 3.9E-80 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Gene3D G3DSA:3.30.300.30 448 546 1.3E-25 T 06-07-2017 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 SUPERFAMILY SSF56801 21 550 7.2E-121 T 06-07-2017 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 205 216 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 463 538 1.0E-9 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Gene3D G3DSA:3.40.50.980 214 362 2.9E-28 T 06-07-2017 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Pfam PF00501 AMP-binding enzyme 33 453 6.3E-76 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Gene3D G3DSA:2.30.38.10 371 447 1.2E-21 T 06-07-2017 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Gene3D G3DSA:3.40.50.980 24 139 7.2E-30 T 06-07-2017 CAL12_RS00150 0c25787f62403e8acee19eefc3ee6f0e 572 Gene3D G3DSA:3.40.50.980 190 213 7.2E-30 T 06-07-2017 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 Gene3D G3DSA:3.40.190.10 93 187 5.3E-24 T 06-07-2017 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 SUPERFAMILY SSF46785 6 116 1.87E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.2E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 Pfam PF03466 LysR substrate binding domain 94 298 8.4E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 SUPERFAMILY SSF53850 95 301 1.68E-45 T 06-07-2017 CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 Gene3D G3DSA:1.10.10.10 8 89 8.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21115 497413f7fa9db3477c2909c9eeac8db3 312 Gene3D G3DSA:3.40.190.10 188 266 5.9E-21 T 06-07-2017 CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 PIRSF PIRSF006305 3 195 3.2E-43 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 Hamap MF_00528 Septum formation protein Maf [maf]. 7 193 27.896 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 186 7.8E-41 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 Pfam PF02545 Maf-like protein 7 187 1.6E-41 T 06-07-2017 IPR003697 Maf-like protein GO:0005737 CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 SUPERFAMILY SSF52972 5 187 2.75E-53 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS08335 3e775a9aa720d528bb571914c2288ad6 201 Gene3D G3DSA:3.90.950.10 7 191 5.2E-51 T 06-07-2017 IPR029001 Inosine triphosphate pyrophosphatase-like CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 SMART SM00382 90 243 5.4E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 SUPERFAMILY SSF54211 254 268 1.93E-38 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 SUPERFAMILY SSF54211 302 453 1.93E-38 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 SUPERFAMILY SSF52540 68 287 4.62E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 9.4E-194 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 Pfam PF13481 AAA domain 75 221 9.1E-18 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 Gene3D G3DSA:3.30.230.10 283 452 2.5E-31 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 173 197 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 10 34 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 123 140 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 247 273 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 321 344 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 212 240 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 PRINTS PR01874 DNA repair protein radA signature 82 110 4.8E-95 T 06-07-2017 CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 Gene3D G3DSA:3.40.50.300 61 274 1.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18095 8eaf5c81c4f72e74e1909b80314d9dae 456 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.616 T 06-07-2017 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CAL12_RS15290 f87461b00b33ca947bed5cc0680cfc45 309 Pfam PF02678 Pirin 26 131 2.8E-33 T 06-07-2017 IPR003829 Pirin, N-terminal domain CAL12_RS15290 f87461b00b33ca947bed5cc0680cfc45 309 Gene3D G3DSA:2.60.120.10 18 255 2.5E-65 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS15290 f87461b00b33ca947bed5cc0680cfc45 309 Pfam PF05726 Pirin C-terminal cupin domain 186 283 5.7E-28 T 06-07-2017 IPR008778 Pirin, C-terminal domain CAL12_RS15290 f87461b00b33ca947bed5cc0680cfc45 309 PIRSF PIRSF006232 8 291 3.5E-87 T 06-07-2017 IPR012093 Pirin CAL12_RS15290 f87461b00b33ca947bed5cc0680cfc45 309 SUPERFAMILY SSF51182 14 287 4.2E-79 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03040 c10f66a02d0cf6e01a200991dc6abe74 511 Pfam PF08666 SAF domain 15 84 8.5E-15 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS03040 c10f66a02d0cf6e01a200991dc6abe74 511 SMART SM00858 15 84 2.3E-16 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS03040 c10f66a02d0cf6e01a200991dc6abe74 511 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 109 509 3.7E-163 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 SMART SM00862 145 218 1.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 Gene3D G3DSA:1.10.10.10 125 220 1.8E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 SMART SM00448 1 112 4.1E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 Pfam PF00072 Response regulator receiver domain 3 112 9.0E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 1.9E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 SUPERFAMILY SSF52172 1 174 1.17E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS09470 4d45388d9b5661928b977e911579f547 229 Gene3D G3DSA:3.40.50.2300 1 119 1.7E-36 T 06-07-2017 CAL12_RS04455 11686bbe606eb9d3e19c46c00ce3986f 228 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 85 178 6.4E-14 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAL12_RS04455 11686bbe606eb9d3e19c46c00ce3986f 228 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 228 42.214 T 06-07-2017 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 CAL12_RS04455 11686bbe606eb9d3e19c46c00ce3986f 228 SUPERFAMILY SSF51197 4 180 5.7E-7 T 06-07-2017 CAL12_RS04455 11686bbe606eb9d3e19c46c00ce3986f 228 SMART SM00702 2 179 3.1E-18 T 06-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 SUPERFAMILY SSF53067 114 235 9.19E-16 T 06-07-2017 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 302 434 6.2E-27 T 06-07-2017 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 Gene3D G3DSA:3.40.630.30 293 437 2.2E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 SUPERFAMILY SSF55729 293 437 3.6E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 237 5.5E-54 T 06-07-2017 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 Pfam PF00583 Acetyltransferase (GNAT) family 339 411 5.0E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 SUPERFAMILY SSF53067 5 107 8.63E-22 T 06-07-2017 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 Gene3D G3DSA:3.30.420.40 5 136 8.4E-34 T 06-07-2017 CAL12_RS19580 f602e982df69971355f4b0e37b9001b0 446 Pfam PF00814 Glycoprotease family 37 147 1.6E-25 T 06-07-2017 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CAL12_RS00675 26d5b55f26400d91a55598c9c616320b 304 SUPERFAMILY SSF103481 53 154 6.93E-15 T 06-07-2017 CAL12_RS00675 26d5b55f26400d91a55598c9c616320b 304 SUPERFAMILY SSF103481 199 301 3.66E-10 T 06-07-2017 CAL12_RS00675 26d5b55f26400d91a55598c9c616320b 304 Pfam PF00892 EamA-like transporter family 166 297 1.4E-15 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS00675 26d5b55f26400d91a55598c9c616320b 304 Pfam PF00892 EamA-like transporter family 25 151 9.9E-24 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS15630 e86aaa080afad858789d19dea2cc7624 312 SUPERFAMILY SSF53474 35 298 7.3E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS15630 e86aaa080afad858789d19dea2cc7624 312 Gene3D G3DSA:3.40.50.1820 49 300 1.1E-47 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS15630 e86aaa080afad858789d19dea2cc7624 312 Pfam PF07859 alpha/beta hydrolase fold 79 264 4.8E-18 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS12350 c6b978f4b82126aa2c7b0561977f1d03 415 Gene3D G3DSA:1.20.1250.20 19 207 1.2E-17 T 06-07-2017 CAL12_RS12350 c6b978f4b82126aa2c7b0561977f1d03 415 Gene3D G3DSA:1.20.1250.20 235 406 4.2E-10 T 06-07-2017 CAL12_RS12350 c6b978f4b82126aa2c7b0561977f1d03 415 SUPERFAMILY SSF103473 18 406 3.01E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12350 c6b978f4b82126aa2c7b0561977f1d03 415 Pfam PF05977 Transmembrane secretion effector 16 413 2.4E-32 T 06-07-2017 IPR010290 Transmembrane secretion effector CAL12_RS03180 84a7897e72c06d557927c3c4d7ccaa39 263 Gene3D G3DSA:3.40.225.10 17 229 6.6E-63 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS03180 84a7897e72c06d557927c3c4d7ccaa39 263 SUPERFAMILY SSF53639 13 230 1.82E-61 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS03180 84a7897e72c06d557927c3c4d7ccaa39 263 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 202 7.0E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS03180 84a7897e72c06d557927c3c4d7ccaa39 263 SMART SM01007 22 203 1.2E-62 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Gene3D G3DSA:3.40.630.30 732 875 3.1E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Pfam PF13380 CoA binding domain 14 138 1.0E-21 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SUPERFAMILY SSF52210 299 455 3.79E-37 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 292 8.3E-55 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Gene3D G3DSA:3.40.50.261 137 289 2.3E-30 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Gene3D G3DSA:3.40.50.720 3 136 4.8E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Gene3D G3DSA:3.30.470.20 494 596 1.3E-4 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Pfam PF13549 ATP-grasp domain 482 703 4.8E-82 T 06-07-2017 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SUPERFAMILY SSF52210 133 298 1.57E-46 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SUPERFAMILY SSF51735 2 143 5.12E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Gene3D G3DSA:3.40.50.261 290 444 5.5E-17 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SUPERFAMILY SSF55729 732 876 6.38E-19 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 Pfam PF13302 Acetyltransferase (GNAT) domain 734 872 1.0E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SUPERFAMILY SSF56059 490 711 4.86E-42 T 06-07-2017 CAL12_RS14380 f4398413a40695a323710763ac240ce1 919 SMART SM00881 9 104 1.2E-29 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Pfam PF08335 GlnD PII-uridylyltransferase 298 442 2.2E-39 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Pfam PF08335 GlnD PII-uridylyltransferase 848 941 5.4E-7 T 06-07-2017 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Gene3D G3DSA:3.30.460.10 677 832 6.9E-49 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Gene3D G3DSA:3.30.460.10 107 286 6.8E-52 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 SUPERFAMILY SSF81593 288 443 4.24E-36 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 18 966 18.191 T 06-07-2017 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 SUPERFAMILY SSF81301 561 836 1.44E-70 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 SUPERFAMILY SSF81593 836 964 9.42E-31 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 SUPERFAMILY SSF81301 25 287 1.77E-63 T 06-07-2017 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 587 826 2.7E-61 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAL12_RS09055 d4e0714c9e707dd2f048ff92c07c5d4d 976 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 27 259 1.5E-55 T 06-07-2017 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 SMART SM01217 705 774 7.1E-31 T 06-07-2017 IPR026891 Fibronectin type III-like domain CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 65 372 3.1E-84 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 Pfam PF14310 Fibronectin type III-like domain 706 774 4.0E-22 T 06-07-2017 IPR026891 Fibronectin type III-like domain CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 415 668 6.3E-61 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 Gene3D G3DSA:3.40.50.1700 403 671 9.9E-82 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 PRINTS PR00133 Glycosyl hydrolase family 3 signature 140 159 5.8E-24 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 PRINTS PR00133 Glycosyl hydrolase family 3 signature 293 311 5.8E-24 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 PRINTS PR00133 Glycosyl hydrolase family 3 signature 186 202 5.8E-24 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 PRINTS PR00133 Glycosyl hydrolase family 3 signature 223 239 5.8E-24 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 PRINTS PR00133 Glycosyl hydrolase family 3 signature 121 137 5.8E-24 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 Gene3D G3DSA:3.20.20.300 47 385 8.3E-108 T 06-07-2017 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 293 310 - T 06-07-2017 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 SUPERFAMILY SSF51445 49 414 8.53E-103 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 SUPERFAMILY SSF52279 415 484 5.1E-61 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAL12_RS09010 5a84603be37befb89bd316c1b6c17b87 785 SUPERFAMILY SSF52279 515 671 5.1E-61 T 06-07-2017 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CAL12_RS09130 2dd72cb7d7fb124fa185592a83959335 446 Gene3D G3DSA:3.40.190.10 171 370 6.9E-21 T 06-07-2017 CAL12_RS09130 2dd72cb7d7fb124fa185592a83959335 446 Gene3D G3DSA:3.40.190.10 46 170 7.1E-11 T 06-07-2017 CAL12_RS09130 2dd72cb7d7fb124fa185592a83959335 446 Pfam PF13416 Bacterial extracellular solute-binding protein 55 370 3.0E-26 T 06-07-2017 CAL12_RS09130 2dd72cb7d7fb124fa185592a83959335 446 SUPERFAMILY SSF53850 38 439 4.35E-43 T 06-07-2017 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 Gene3D G3DSA:3.40.50.620 2 207 1.6E-75 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 SUPERFAMILY SSF52374 4 333 3.1E-79 T 06-07-2017 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 333 1.5E-90 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 SUPERFAMILY SSF160113 356 404 1.03E-8 T 06-07-2017 IPR010879 Domain of unknown function DUF1508 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 Gene3D G3DSA:1.10.240.10 208 300 1.5E-23 T 06-07-2017 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 334 35.727 T 06-07-2017 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 4.5E-20 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 151 172 4.5E-20 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 4.5E-20 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 203 213 4.5E-20 T 06-07-2017 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CAL12_RS19205 67610978870302ea0a4384b76d8d6f32 452 Pfam PF00579 tRNA synthetases class I (W and Y) 3 254 1.3E-53 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS23280 aa43fd485ab71a43e39f4e7f759c3024 333 SUPERFAMILY SSF53850 116 293 1.38E-10 T 06-07-2017 CAL12_RS23280 aa43fd485ab71a43e39f4e7f759c3024 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 329 2.8E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23280 aa43fd485ab71a43e39f4e7f759c3024 333 PIRSF PIRSF017082 1 332 7.9E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 SUPERFAMILY SSF55729 199 342 6.32E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 SUPERFAMILY SSF55729 7 174 1.71E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 Pfam PF13673 Acetyltransferase (GNAT) domain 58 150 7.5E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 Pfam PF13673 Acetyltransferase (GNAT) domain 245 331 1.4E-10 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 Gene3D G3DSA:3.40.630.30 5 175 3.0E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS03515 34d4df66297fbf2c8efb201754688f29 345 Gene3D G3DSA:3.40.630.30 199 343 2.1E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 SUPERFAMILY SSF51556 64 367 9.46E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 SUPERFAMILY SSF51338 8 64 5.1E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 SUPERFAMILY SSF51338 366 441 5.1E-28 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 Pfam PF01979 Amidohydrolase family 62 415 6.3E-47 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 Gene3D G3DSA:3.20.20.140 67 375 1.5E-68 T 06-07-2017 CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 Gene3D G3DSA:2.30.40.10 376 418 3.6E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23360 552a880eafa8242e181062522d0d1714 445 Gene3D G3DSA:2.30.40.10 8 66 3.6E-16 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 SUPERFAMILY SSF53335 86 220 9.14E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 SUPERFAMILY SSF53335 302 328 9.14E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 PIRSF PIRSF018005 14 340 7.3E-106 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 Gene3D G3DSA:3.40.50.150 300 338 2.9E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 Gene3D G3DSA:3.40.50.150 99 255 2.9E-8 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 213 335 1.5E-42 T 06-07-2017 IPR019257 Histidine-specific methyltransferase, SAM-dependent CAL12_RS17685 42c91224a45380d4e121e77c55ffe277 340 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 41 337 5.3E-111 T 06-07-2017 IPR017804 Methyltransferase EgtD-like CAL12_RS23765 045b7f23021400685600f59623c58053 416 Pfam PF00266 Aminotransferase class-V 47 405 2.0E-43 T 06-07-2017 IPR000192 Aminotransferase class V domain CAL12_RS23765 045b7f23021400685600f59623c58053 416 Gene3D G3DSA:3.40.640.10 48 291 6.7E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS23765 045b7f23021400685600f59623c58053 416 SUPERFAMILY SSF53383 20 413 7.85E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS23765 045b7f23021400685600f59623c58053 416 Gene3D G3DSA:3.90.1150.10 292 411 4.1E-22 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00406 Cytochrome B5 reductase signature 213 221 9.4E-9 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00406 Cytochrome B5 reductase signature 117 136 9.4E-9 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00406 Cytochrome B5 reductase signature 92 106 9.4E-9 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00406 Cytochrome B5 reductase signature 154 165 9.4E-9 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00406 Cytochrome B5 reductase signature 56 63 9.4E-9 T 06-07-2017 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 SUPERFAMILY SSF52343 110 246 5.76E-33 T 06-07-2017 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 SUPERFAMILY SSF63380 4 106 3.4E-26 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Gene3D G3DSA:2.40.30.10 3 95 6.7E-26 T 06-07-2017 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Pfam PF00175 Oxidoreductase NAD-binding domain 120 226 1.7E-16 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 5 355 7.7E-141 T 06-07-2017 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Gene3D G3DSA:3.40.50.80 96 238 4.6E-37 T 06-07-2017 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Gene3D G3DSA:3.10.20.30 239 356 2.7E-33 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 SUPERFAMILY SSF54292 235 353 1.23E-30 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 117 136 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 142 151 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 165 3.6E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 345 1.2E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 Pfam PF00970 Oxidoreductase FAD-binding domain 9 104 1.9E-12 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS18665 d929e5e4d9a9d1662077c81bbdd0054d 358 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 303 311 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 Gene3D G3DSA:3.40.50.300 1 217 4.4E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17460 85667aa348c2f963c067fef674554371 217 Hamap MF_00235 Adenylate kinase [adk]. 1 216 53.906 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 PRINTS PR00094 Adenylate kinase signature 156 171 1.8E-35 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 PRINTS PR00094 Adenylate kinase signature 173 187 1.8E-35 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.8E-35 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.8E-35 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.8E-35 T 06-07-2017 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 SUPERFAMILY SSF52540 1 185 4.47E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17460 85667aa348c2f963c067fef674554371 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 4.7E-17 T 06-07-2017 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 Pfam PF00406 Adenylate kinase 5 183 2.0E-57 T 06-07-2017 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 187 1.3E-73 T 06-07-2017 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219 CAL12_RS17460 85667aa348c2f963c067fef674554371 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 06-07-2017 CAL12_RS00605 bcc5005124fec02c4b5cc0ce217d46b1 336 Gene3D G3DSA:3.40.190.10 9 122 4.1E-29 T 06-07-2017 CAL12_RS00605 bcc5005124fec02c4b5cc0ce217d46b1 336 Gene3D G3DSA:3.40.190.10 266 322 4.1E-29 T 06-07-2017 CAL12_RS00605 bcc5005124fec02c4b5cc0ce217d46b1 336 Gene3D G3DSA:3.40.190.10 127 265 2.9E-39 T 06-07-2017 CAL12_RS00605 bcc5005124fec02c4b5cc0ce217d46b1 336 SUPERFAMILY SSF53850 35 331 1.98E-61 T 06-07-2017 CAL12_RS00605 bcc5005124fec02c4b5cc0ce217d46b1 336 Pfam PF13343 Bacterial extracellular solute-binding protein 75 301 8.8E-53 T 06-07-2017 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 Pfam PF01958 Domain of unknown function DUF108 167 254 1.3E-30 T 06-07-2017 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 Gene3D G3DSA:3.30.360.10 137 237 1.4E-33 T 06-07-2017 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 PIRSF PIRSF005227 1 268 1.0E-77 T 06-07-2017 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 Gene3D G3DSA:3.40.50.720 4 136 8.3E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 SUPERFAMILY SSF51735 4 132 1.24E-17 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 SUPERFAMILY SSF55347 122 237 2.68E-25 T 06-07-2017 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 3 266 31.354 T 06-07-2017 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CAL12_RS20595 07e4c7174bd3f86698455c06e0577070 268 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 119 1.5E-16 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAL12_RS00060 070dc4738c5ee9e3d848aa0ce97d7922 388 Pfam PF02515 CoA-transferase family III 4 364 1.8E-112 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS00060 070dc4738c5ee9e3d848aa0ce97d7922 388 Gene3D G3DSA:3.40.50.10540 2 213 4.5E-103 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS00060 070dc4738c5ee9e3d848aa0ce97d7922 388 Gene3D G3DSA:3.40.50.10540 304 388 4.5E-103 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS00060 070dc4738c5ee9e3d848aa0ce97d7922 388 Gene3D G3DSA:3.30.1540.10 219 303 2.2E-24 T 06-07-2017 CAL12_RS00060 070dc4738c5ee9e3d848aa0ce97d7922 388 SUPERFAMILY SSF89796 2 388 1.44E-127 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 399 4.3E-12 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 SUPERFAMILY SSF55073 241 406 8.63E-14 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 SMART SM00267 224 405 2.1E-7 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 Pfam PF00563 EAL domain 422 646 1.8E-26 T 06-07-2017 IPR001633 EAL domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 Pfam PF16448 LapD/MoxY periplasmic domain 24 144 3.9E-39 T 06-07-2017 IPR032244 LapD/MoxY, periplasmic domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 Gene3D G3DSA:3.20.20.450 420 646 2.7E-25 T 06-07-2017 IPR001633 EAL domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 Gene3D G3DSA:3.30.70.270 237 409 3.0E-17 T 06-07-2017 CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 SUPERFAMILY SSF141868 422 646 3.27E-27 T 06-07-2017 IPR001633 EAL domain CAL12_RS11565 27ced26607a02bbc3fbe3df8f13d02f6 655 SMART SM00052 416 649 2.9E-7 T 06-07-2017 IPR001633 EAL domain CAL12_RS10585 fe152a663ffea6e2577ab31a8d78613e 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 278 7.0E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10585 fe152a663ffea6e2577ab31a8d78613e 287 Gene3D G3DSA:1.10.3720.10 85 278 5.3E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10585 fe152a663ffea6e2577ab31a8d78613e 287 SUPERFAMILY SSF161098 86 273 1.31E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 PIRSF PIRSF009393 1 753 5.1E-276 T 06-07-2017 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Gene3D G3DSA:3.90.1150.10 459 627 5.5E-69 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 SUPERFAMILY SSF53383 151 604 1.8E-115 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 611 735 5.1E-46 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Gene3D G3DSA:3.40.640.10 151 456 4.4E-113 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 584 1.7E-151 T 06-07-2017 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Gene3D G3DSA:3.90.100.10 628 752 9.0E-37 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 SUPERFAMILY SSF55904 606 751 1.83E-44 T 06-07-2017 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CAL12_RS02635 46251123695f852d4ded4974e9c497e0 756 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 2.5E-38 T 06-07-2017 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 CAL12_RS00090 d9c2d8f2d514ff72620a395c00dd9870 417 Gene3D G3DSA:3.20.20.70 9 384 8.2E-128 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00090 d9c2d8f2d514ff72620a395c00dd9870 417 PIRSF PIRSF000138 2 386 2.7E-124 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS00090 d9c2d8f2d514ff72620a395c00dd9870 417 Pfam PF01070 FMN-dependent dehydrogenase 19 382 2.0E-128 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS00090 d9c2d8f2d514ff72620a395c00dd9870 417 SUPERFAMILY SSF51395 8 381 9.77E-98 T 06-07-2017 CAL12_RS00090 d9c2d8f2d514ff72620a395c00dd9870 417 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 279 285 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Pfam PF13692 Glycosyl transferases group 1 239 359 3.5E-7 T 06-07-2017 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Pfam PF13450 NAD(P)-binding Rossmann-like domain 458 524 1.4E-15 T 06-07-2017 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 SUPERFAMILY SSF51971 453 716 1.65E-50 T 06-07-2017 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 SUPERFAMILY SSF51971 781 815 1.65E-50 T 06-07-2017 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 SUPERFAMILY SSF54373 698 763 4.32E-21 T 06-07-2017 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Pfam PF03275 UDP-galactopyranose mutase 600 796 1.5E-80 T 06-07-2017 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 454 809 6.7E-120 T 06-07-2017 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Gene3D G3DSA:3.40.50.720 634 707 2.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Gene3D G3DSA:3.40.50.720 451 532 2.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 Gene3D G3DSA:3.40.50.720 771 813 2.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13370 d216c2ddfc57990e87ee9d0a4db2d97c 829 SUPERFAMILY SSF53756 84 388 1.05E-13 T 06-07-2017 CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 SUPERFAMILY SSF52821 2 140 3.4E-39 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 Gene3D G3DSA:3.40.250.10 160 283 2.3E-32 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 Gene3D G3DSA:3.40.250.10 1 143 1.3E-43 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 SMART SM00450 7 133 2.0E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 SMART SM00450 158 278 6.0E-8 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 Pfam PF00581 Rhodanese-like domain 161 274 7.9E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 Pfam PF00581 Rhodanese-like domain 9 129 4.6E-15 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS18330 24b4f0ccfc4735a450b90c5f9521dde2 283 SUPERFAMILY SSF52821 161 283 9.56E-31 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS21570 b2497821a44746105883fa7435627913 94 Pfam PF13937 Domain of unknown function (DUF4212) 25 91 1.9E-18 T 06-07-2017 IPR019886 Sodium symporter small subunit, predicted CAL12_RS21570 b2497821a44746105883fa7435627913 94 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 25 91 1.7E-19 T 06-07-2017 IPR019886 Sodium symporter small subunit, predicted CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 Gene3D G3DSA:3.40.50.300 1 227 1.6E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 SMART SM00382 26 213 3.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 PIRSF PIRSF039085 1 244 4.6E-98 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 SUPERFAMILY SSF52540 1 226 2.2E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05375 de018e210020bceac00e2381fe189d2c 245 Pfam PF00005 ABC transporter 18 165 6.8E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 Pfam PF01575 MaoC like domain 168 268 5.9E-22 T 06-07-2017 IPR002539 MaoC-like domain CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 SUPERFAMILY SSF54637 177 283 4.66E-24 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 Gene3D G3DSA:3.10.129.10 3 139 3.1E-32 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 Gene3D G3DSA:3.10.129.10 140 283 1.8E-31 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 SUPERFAMILY SSF54637 6 151 2.12E-29 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01415 6526a2a28be2800424fa0bfe122774f4 291 Pfam PF13452 N-terminal half of MaoC dehydratase 44 130 2.0E-6 T 06-07-2017 CAL12_RS07825 61a23a7c628fb265645f42e3b4ecf9ee 117 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 95 5.3E-16 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07825 61a23a7c628fb265645f42e3b4ecf9ee 117 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 94 1.9E-13 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS07825 61a23a7c628fb265645f42e3b4ecf9ee 117 SUPERFAMILY SSF81343 9 108 9.48E-18 T 06-07-2017 CAL12_RS07825 61a23a7c628fb265645f42e3b4ecf9ee 117 Gene3D G3DSA:1.20.1300.10 7 97 3.5E-19 T 06-07-2017 CAL12_RS10265 160c4bb613449ef23574fab5b68816ac 325 SUPERFAMILY SSF53850 115 283 1.01E-12 T 06-07-2017 CAL12_RS10265 160c4bb613449ef23574fab5b68816ac 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 2.3E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10265 160c4bb613449ef23574fab5b68816ac 325 PIRSF PIRSF017082 1 324 8.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 305 482 6.2E-74 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 281 3.0E-77 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 SUPERFAMILY SSF143968 350 514 1.96E-66 T 06-07-2017 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 458 1.3E-165 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 Gene3D G3DSA:1.20.5.570 482 514 1.1E-18 T 06-07-2017 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 514 72.536 T 06-07-2017 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 Gene3D G3DSA:3.40.1670.10 364 481 7.3E-52 T 06-07-2017 CAL12_RS04975 19decbc18eaf49ed37e12f93ecc58cd0 514 SUPERFAMILY SSF50475 3 349 6.67E-111 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 SUPERFAMILY SSF46785 4 86 2.47E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 Gene3D G3DSA:3.40.190.10 92 177 2.6E-19 T 06-07-2017 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 Gene3D G3DSA:3.40.190.10 178 265 5.1E-18 T 06-07-2017 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 Gene3D G3DSA:1.10.10.10 4 87 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.2E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 SUPERFAMILY SSF53850 92 289 1.12E-39 T 06-07-2017 CAL12_RS21790 926e1cf597a8dfce35bcd2c4bdc105a3 296 Pfam PF03466 LysR substrate binding domain 91 289 1.3E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 Pfam PF00106 short chain dehydrogenase 26 218 2.5E-59 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 26 43 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 1.3E-42 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 SUPERFAMILY SSF51735 21 280 1.74E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 Gene3D G3DSA:3.40.50.720 18 279 1.1E-85 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 6.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 103 114 6.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25005 794ae782cb2b1d7078d408ac2ce07741 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 6.4E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10080 3fbddd2ac71f477390548acbb5fda6eb 237 Pfam PF00149 Calcineurin-like phosphoesterase 17 192 4.9E-11 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS10080 3fbddd2ac71f477390548acbb5fda6eb 237 Gene3D G3DSA:3.60.21.10 12 222 2.2E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS10080 3fbddd2ac71f477390548acbb5fda6eb 237 SUPERFAMILY SSF56300 14 219 5.38E-37 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS27055 ba3262d8ae9ee5d78dcc2d3a06e7ab4d 286 Gene3D G3DSA:3.60.10.10 4 165 4.3E-15 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS27055 ba3262d8ae9ee5d78dcc2d3a06e7ab4d 286 SUPERFAMILY SSF56219 213 283 2.22E-40 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS27055 ba3262d8ae9ee5d78dcc2d3a06e7ab4d 286 SUPERFAMILY SSF56219 4 166 2.22E-40 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS27055 ba3262d8ae9ee5d78dcc2d3a06e7ab4d 286 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 276 2.9E-18 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 Gene3D G3DSA:3.10.105.10 294 485 1.2E-33 T 06-07-2017 CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 PIRSF PIRSF002741 1 516 9.5E-78 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 SUPERFAMILY SSF53850 30 516 2.58E-103 T 06-07-2017 CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 Gene3D G3DSA:3.90.76.10 66 149 2.4E-19 T 06-07-2017 CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 Gene3D G3DSA:3.40.190.10 150 293 7.4E-35 T 06-07-2017 CAL12_RS11585 f995641f07091b51447c9d3190c6553c 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 439 4.5E-72 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 SUPERFAMILY SSF56091 208 414 2.82E-54 T 06-07-2017 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Gene3D G3DSA:3.30.1490.70 369 414 4.2E-15 T 06-07-2017 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Gene3D G3DSA:3.30.1490.70 208 242 4.2E-15 T 06-07-2017 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Gene3D G3DSA:3.30.470.30 243 358 5.1E-32 T 06-07-2017 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Pfam PF04675 DNA ligase N terminus 3 161 2.8E-18 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 545 3.4E-214 T 06-07-2017 IPR026333 ATP-dependent DNA ligase, PP_1105 family CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Pfam PF01068 ATP dependent DNA ligase domain 234 414 1.8E-27 T 06-07-2017 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Gene3D G3DSA:2.40.50.140 419 545 2.2E-36 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 SUPERFAMILY SSF117018 3 184 9.29E-5 T 06-07-2017 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 SUPERFAMILY SSF50249 419 545 5.14E-29 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 Pfam PF04679 ATP dependent DNA ligase C terminal region 435 530 1.8E-9 T 06-07-2017 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CAL12_RS16130 664c6113d05888128447da06c32ae53b 553 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 238 246 - T 06-07-2017 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CAL12_RS01460 d6f6cdf064fb69a3689d9d7b469fc85d 157 Pfam PF13452 N-terminal half of MaoC dehydratase 30 147 9.0E-18 T 06-07-2017 CAL12_RS01460 d6f6cdf064fb69a3689d9d7b469fc85d 157 SUPERFAMILY SSF54637 18 156 3.09E-29 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01460 d6f6cdf064fb69a3689d9d7b469fc85d 157 Gene3D G3DSA:3.10.129.10 16 156 9.2E-27 T 06-07-2017 IPR029069 HotDog domain CAL12_RS27180 5543ce9f58dc0d6d385b026aeee5b05a 223 SUPERFAMILY SSF53850 26 222 1.18E-27 T 06-07-2017 CAL12_RS27180 5543ce9f58dc0d6d385b026aeee5b05a 223 Gene3D G3DSA:3.40.190.10 29 112 4.7E-29 T 06-07-2017 CAL12_RS27180 5543ce9f58dc0d6d385b026aeee5b05a 223 Pfam PF03466 LysR substrate binding domain 26 221 1.3E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS27180 5543ce9f58dc0d6d385b026aeee5b05a 223 Gene3D G3DSA:3.40.190.10 113 193 1.1E-16 T 06-07-2017 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 SUPERFAMILY SSF51905 327 368 1.38E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 SUPERFAMILY SSF51905 5 223 1.38E-39 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Gene3D G3DSA:3.30.9.10 226 316 1.1E-4 T 06-07-2017 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Gene3D G3DSA:3.30.9.10 88 139 1.1E-4 T 06-07-2017 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Gene3D G3DSA:3.50.50.60 326 362 6.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Gene3D G3DSA:3.50.50.60 140 221 6.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Gene3D G3DSA:3.50.50.60 3 85 6.4E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS05385 640b1c644e27f45e050433459dc34203 371 Pfam PF01266 FAD dependent oxidoreductase 6 363 7.0E-64 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 Gene3D G3DSA:3.40.50.150 3 209 8.0E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 SUPERFAMILY SSF53335 3 209 8.74E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 20 34 4.4E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 144 161 4.4E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 186 206 4.4E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 163 181 4.4E-24 T 06-07-2017 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 24 30 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 Pfam PF01555 DNA methylase 141 202 1.0E-21 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAL12_RS20345 57c25fb03381cde55c73b2f8cf26f416 215 Pfam PF01555 DNA methylase 21 124 4.5E-8 T 06-07-2017 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 Pfam PF00106 short chain dehydrogenase 7 184 8.1E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 3.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 3.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.7E-21 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 SUPERFAMILY SSF51735 1 207 2.28E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 Gene3D G3DSA:3.40.50.720 2 195 4.2E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 3.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 3.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 3.4E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS12750 1dba2fb593e0330ce52c728ae3b7d27e 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.4E-46 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 5.2E-65 T 06-07-2017 CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 1.3E-4 T 06-07-2017 CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 SUPERFAMILY SSF51735 4 243 4.31E-82 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 Gene3D G3DSA:3.40.50.720 2 243 9.0E-87 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.3E-12 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08365 dcdd95b1d82812d4ece3439e6a0c0f0a 243 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 8.3E-98 T 06-07-2017 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 143 160 - T 06-07-2017 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 Pfam PF00248 Aldo/keto reductase family 18 320 3.2E-71 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 Gene3D G3DSA:3.20.20.100 5 326 9.3E-100 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 SUPERFAMILY SSF51430 5 326 1.83E-99 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 PRINTS PR00069 Aldo-keto reductase signature 112 130 2.0E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS10980 5bbb3f078b9e7b3e73422a6b2ce22c93 332 PRINTS PR00069 Aldo-keto reductase signature 143 160 2.0E-7 T 06-07-2017 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 8.4E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 Gene3D G3DSA:1.10.10.10 5 88 1.1E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 SUPERFAMILY SSF53850 96 316 1.5E-29 T 06-07-2017 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 Gene3D G3DSA:3.40.190.10 97 199 1.3E-26 T 06-07-2017 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.5E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 Pfam PF03466 LysR substrate binding domain 97 315 5.9E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 Gene3D G3DSA:3.40.190.10 200 279 1.9E-23 T 06-07-2017 CAL12_RS20600 742c558f57a8f959f6fb51b857d76c5c 335 SUPERFAMILY SSF46785 6 88 2.23E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01020 4f1042bc0a9d5f3ded4841fb3e105ef1 207 Gene3D G3DSA:3.40.30.10 31 140 3.8E-5 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS01020 4f1042bc0a9d5f3ded4841fb3e105ef1 207 SUPERFAMILY SSF52833 65 201 6.33E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS03500 b7d5ef8576cb992f8402b547a9d55d8c 168 Pfam PF12973 ChrR Cupin-like domain 31 105 1.4E-7 T 06-07-2017 IPR025979 ChrR-like cupin domain CAL12_RS03500 b7d5ef8576cb992f8402b547a9d55d8c 168 SUPERFAMILY SSF51182 14 107 1.86E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03500 b7d5ef8576cb992f8402b547a9d55d8c 168 Gene3D G3DSA:2.60.120.10 16 153 3.0E-34 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 SUPERFAMILY SSF55957 361 445 7.19E-19 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 138 3.0E-41 T 06-07-2017 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 178 197 2.4E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 2.4E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 2.4E-12 T 06-07-2017 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 SUPERFAMILY SSF53738 3 185 1.06E-46 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 SUPERFAMILY SSF53738 262 369 5.49E-29 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Gene3D G3DSA:3.40.120.10 181 254 1.1E-22 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 367 1.0E-27 T 06-07-2017 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 SUPERFAMILY SSF53738 160 260 8.63E-27 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 442 3.0E-171 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Gene3D G3DSA:3.40.120.10 255 371 3.0E-32 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Gene3D G3DSA:3.30.310.50 372 444 6.6E-14 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 376 444 3.9E-12 T 06-07-2017 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 447 44.676 T 06-07-2017 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 161 258 5.6E-17 T 06-07-2017 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 Gene3D G3DSA:3.40.120.10 4 156 3.5E-46 T 06-07-2017 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS06560 94c5eea7806fe0faa519bf3898d8f8b8 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 06-07-2017 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CAL12_RS16305 375c156a1f44805b058fe11fff640eeb 333 Pfam PF09084 NMT1/THI5 like 87 269 1.5E-11 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS16305 375c156a1f44805b058fe11fff640eeb 333 SUPERFAMILY SSF53850 72 330 1.68E-31 T 06-07-2017 CAL12_RS16305 375c156a1f44805b058fe11fff640eeb 333 Gene3D G3DSA:3.40.190.10 125 214 8.6E-12 T 06-07-2017 CAL12_RS23745 2afaf9240514013cefefb9e3a88179b9 128 SUPERFAMILY SSF52091 12 100 3.14E-17 T 06-07-2017 IPR002645 STAS domain CAL12_RS23745 2afaf9240514013cefefb9e3a88179b9 128 Gene3D G3DSA:3.30.750.24 13 100 7.5E-20 T 06-07-2017 IPR002645 STAS domain CAL12_RS23745 2afaf9240514013cefefb9e3a88179b9 128 Pfam PF13466 STAS domain 14 96 3.1E-18 T 06-07-2017 IPR002645 STAS domain CAL12_RS21740 4e5e9f47a4aa30ed0956d2b202f3e393 497 Pfam PF00171 Aldehyde dehydrogenase family 35 492 1.6E-149 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS21740 4e5e9f47a4aa30ed0956d2b202f3e393 497 SUPERFAMILY SSF53720 18 494 3.67E-150 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS21740 4e5e9f47a4aa30ed0956d2b202f3e393 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS21740 4e5e9f47a4aa30ed0956d2b202f3e393 497 Gene3D G3DSA:3.40.309.10 277 467 1.0E-59 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS21740 4e5e9f47a4aa30ed0956d2b202f3e393 497 Gene3D G3DSA:3.40.605.10 21 276 1.5E-84 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 Gene3D G3DSA:1.10.10.60 1 65 6.1E-21 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 SUPERFAMILY SSF46689 1 72 6.48E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.4E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 SUPERFAMILY SSF48498 80 192 1.97E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 79 167 3.9E-8 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS13855 74948aa4df94b4b4c21942e788deb72a 196 Gene3D G3DSA:1.10.357.10 72 193 2.4E-25 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 0.0014 T 06-07-2017 CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.9E-24 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 SUPERFAMILY SSF51735 1 246 1.4E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 Pfam PF00106 short chain dehydrogenase 3 185 2.3E-50 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 Gene3D G3DSA:3.40.50.720 2 247 1.9E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20655 5cca79050f3d6c2969c2ff90a7c9d6e7 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 2.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 Pfam PF00005 ABC transporter 18 164 1.5E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 SUPERFAMILY SSF50331 239 350 6.63E-6 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 242 4.4E-121 T 06-07-2017 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 SMART SM00382 27 214 1.4E-20 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 Gene3D G3DSA:3.40.50.300 3 243 4.7E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 SUPERFAMILY SSF52540 3 243 4.64E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18745 3d3511ff1309247450c24a4439d9b3e7 353 Pfam PF12857 TOBE-like domain 288 344 2.8E-12 T 06-07-2017 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 CAL12_RS09280 6ec24dc0ddeaf849bdd2c5bb86c86898 179 Pfam PF00156 Phosphoribosyl transferase domain 13 159 2.1E-25 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS09280 6ec24dc0ddeaf849bdd2c5bb86c86898 179 SUPERFAMILY SSF53271 8 176 6.39E-35 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS09280 6ec24dc0ddeaf849bdd2c5bb86c86898 179 Gene3D G3DSA:3.40.50.2020 8 166 2.3E-35 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS22665 08571db7c2d37d5873797223528aa93e 1132 Pfam PF06744 Type VI secretion protein IcmF C-terminal 874 1073 3.2E-55 T 06-07-2017 IPR010623 Type VI secretion system IcmF, C-terminal CAL12_RS22665 08571db7c2d37d5873797223528aa93e 1132 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 20 797 2.1E-152 T 06-07-2017 IPR017731 Type VI secretion system, IcmF CAL12_RS22665 08571db7c2d37d5873797223528aa93e 1132 Pfam PF06761 Intracellular multiplication and human macrophage-killing 514 792 1.3E-58 T 06-07-2017 IPR009612 ImcF-related CAL12_RS22665 08571db7c2d37d5873797223528aa93e 1132 Pfam PF14331 ImcF-related N-terminal domain 189 432 1.8E-62 T 06-07-2017 IPR025743 ImcF-related, N-terminal domain CAL12_RS20495 3bf12969c5d8e02356607807cc9791b8 187 SUPERFAMILY SSF48498 67 160 3.61E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS20495 3bf12969c5d8e02356607807cc9791b8 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 46 2.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20495 3bf12969c5d8e02356607807cc9791b8 187 Gene3D G3DSA:1.10.357.10 2 155 2.3E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS20495 3bf12969c5d8e02356607807cc9791b8 187 SUPERFAMILY SSF46689 1 69 5.34E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 SUPERFAMILY SSF53850 240 440 1.05E-41 T 06-07-2017 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 Gene3D G3DSA:3.40.190.10 240 340 1.0E-23 T 06-07-2017 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 SUPERFAMILY SSF46785 152 261 2.85E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 154 213 2.9E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 180 190 4.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 169 180 4.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 190 201 4.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 Pfam PF03466 LysR substrate binding domain 238 440 1.4E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 Gene3D G3DSA:1.10.10.10 152 236 4.1E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12770 3289371ee4c4d1e208147c293840b3fd 468 Gene3D G3DSA:3.40.190.10 341 410 4.3E-11 T 06-07-2017 CAL12_RS03605 f7afda080287db27a7aeaadc609b23a7 406 Gene3D G3DSA:1.20.1250.20 9 178 6.1E-20 T 06-07-2017 CAL12_RS03605 f7afda080287db27a7aeaadc609b23a7 406 Gene3D G3DSA:1.20.1250.20 217 400 4.9E-20 T 06-07-2017 CAL12_RS03605 f7afda080287db27a7aeaadc609b23a7 406 Pfam PF07690 Major Facilitator Superfamily 16 301 4.8E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS03605 f7afda080287db27a7aeaadc609b23a7 406 SUPERFAMILY SSF103473 9 402 4.05E-44 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19440 90794c912155cfa8eb927f770f93c8d5 218 Gene3D G3DSA:1.20.950.20 10 214 3.4E-62 T 06-07-2017 CAL12_RS19440 90794c912155cfa8eb927f770f93c8d5 218 SUPERFAMILY SSF81342 11 214 6.28E-50 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS19440 90794c912155cfa8eb927f770f93c8d5 218 Pfam PF01292 Prokaryotic cytochrome b561 16 184 8.1E-25 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS19440 90794c912155cfa8eb927f770f93c8d5 218 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 14 213 9.2E-56 T 06-07-2017 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 CAL12_RS22375 d7cb31cb6faa16c1ff552ce9e522cd28 162 Pfam PF05258 Protein of unknown function (DUF721) 34 99 3.5E-9 T 06-07-2017 IPR007922 Protein of unknown function DUF721/UPF0232 CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 1109 1243 5.1E-15 T 06-07-2017 IPR018712 Domain of unknown function DUF2235 CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 916 990 7.7E-14 T 06-07-2017 IPR022385 Rhs repeat-associated core GO:0097264 CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 PRINTS PR00394 RHS protein signature 881 901 2.8E-5 T 06-07-2017 IPR001826 RHS protein CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 PRINTS PR00394 RHS protein signature 957 976 2.8E-5 T 06-07-2017 IPR001826 RHS protein CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 PRINTS PR00394 RHS protein signature 934 954 2.8E-5 T 06-07-2017 IPR001826 RHS protein CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 579 616 1.4E-4 T 06-07-2017 IPR006530 YD repeat CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 483 513 0.0018 T 06-07-2017 IPR006530 YD repeat CAL12_RS00580 3444455b9fde56e929e51db3deb8cddf 1349 Pfam PF05593 RHS Repeat 483 513 2.8E-7 T 06-07-2017 IPR031325 RHS repeat CAL12_RS10065 bd3f74f30fa21feb031348866edb2e95 313 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 35 309 1.7E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10065 bd3f74f30fa21feb031348866edb2e95 313 PIRSF PIRSF017082 2 313 4.3E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10065 bd3f74f30fa21feb031348866edb2e95 313 SUPERFAMILY SSF53850 99 272 4.18E-11 T 06-07-2017 CAL12_RS10605 b6def159ceb2da8d20e1bd5bf2efda0b 312 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 31 183 2.4E-12 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS10605 b6def159ceb2da8d20e1bd5bf2efda0b 312 SUPERFAMILY SSF53187 3 310 2.88E-54 T 06-07-2017 CAL12_RS10605 b6def159ceb2da8d20e1bd5bf2efda0b 312 Gene3D G3DSA:3.40.630.10 30 206 1.1E-9 T 06-07-2017 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 SUPERFAMILY SSF82689 714 805 1.19E-11 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 Pfam PF00924 Mechanosensitive ion channel 603 800 3.0E-39 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 Gene3D G3DSA:2.30.30.60 660 709 3.8E-16 T 06-07-2017 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 SUPERFAMILY SSF50182 645 710 2.03E-15 T 06-07-2017 IPR010920 LSM domain CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 Pfam PF12607 Protein of unknown function (DUF3772) 159 220 2.7E-15 T 06-07-2017 IPR022249 Domain of unknown function DUF3772 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 Gene3D G3DSA:3.30.70.100 727 799 6.7E-8 T 06-07-2017 CAL12_RS19390 565e0299c3fcbb6720d4009a0b2a37fe 837 SUPERFAMILY SSF82861 562 643 1.44E-8 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 SUPERFAMILY SSF161098 300 427 1.57E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 SUPERFAMILY SSF161098 454 587 1.57E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 Gene3D G3DSA:1.10.3720.10 5 274 5.8E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 SUPERFAMILY SSF161098 5 282 1.7E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 276 1.8E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 381 582 1.4E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24915 eacf5b8ce4c9bd4bfda9d93be3553c35 590 Gene3D G3DSA:1.10.3720.10 306 587 9.0E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 Pfam PF02357 Transcription termination factor nusG 3 108 3.2E-27 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 SMART SM00739 123 150 4.8E-6 T 06-07-2017 IPR005824 KOW CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.704 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 06-07-2017 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 Gene3D G3DSA:3.30.70.940 3 114 1.2E-44 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 3.6E-69 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.6E-20 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.6E-20 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.6E-20 T 06-07-2017 IPR001062 Transcription antitermination protein, NusG GO:0032784 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 SMART SM00738 2 111 8.5E-48 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 Gene3D G3DSA:2.30.30.30 116 176 7.9E-32 T 06-07-2017 IPR014722 Ribosomal protein L2 domain 2 CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 Pfam PF00467 KOW motif 126 158 1.9E-7 T 06-07-2017 IPR005824 KOW CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 SUPERFAMILY SSF50104 121 176 8.53E-20 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAL12_RS27775 a68b04feda5c7a3720690ea4603e1705 177 SUPERFAMILY SSF82679 3 113 8.89E-38 T 06-07-2017 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 Pfam PF09339 IclR helix-turn-helix domain 4 53 2.7E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 SUPERFAMILY SSF46785 2 73 3.44E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 SMART SM00346 1 91 2.2E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 SUPERFAMILY SSF55781 75 250 1.57E-32 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 Gene3D G3DSA:3.30.450.40 76 249 2.9E-32 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 Pfam PF01614 Bacterial transcriptional regulator 122 225 1.5E-13 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS19480 b7ec3af8602df8d4e066e65ccfc1b6fa 272 Gene3D G3DSA:1.10.10.10 2 74 1.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24855 d81b1b893b52565aa5242a65b56a36d3 484 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 3 39 6.6E-14 T 06-07-2017 IPR011723 Zinc finger/thioredoxin putative CAL12_RS24855 d81b1b893b52565aa5242a65b56a36d3 484 Pfam PF11906 Protein of unknown function (DUF3426) 333 480 1.0E-42 T 06-07-2017 IPR021834 Protein of unknown function DUF3426 CAL12_RS24855 d81b1b893b52565aa5242a65b56a36d3 484 Pfam PF13719 zinc-ribbon domain 3 38 1.3E-12 T 06-07-2017 IPR011723 Zinc finger/thioredoxin putative CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 Pfam PF00072 Response regulator receiver domain 12 122 1.8E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 SUPERFAMILY SSF46894 138 240 1.47E-27 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 SUPERFAMILY SSF52172 6 131 1.57E-43 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 SMART SM00862 162 238 6.3E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 SMART SM00448 10 121 1.1E-46 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 Gene3D G3DSA:3.40.50.2300 8 132 4.3E-43 T 06-07-2017 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 163 238 2.3E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS19585 303f47aa139c9f6de6b7c9578fa66a1b 244 Gene3D G3DSA:1.10.10.10 138 241 2.6E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20590 9e6a8a3edecb97d86577a99509f740fe 90 Gene3D G3DSA:1.10.10.10 7 52 1.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20590 9e6a8a3edecb97d86577a99509f740fe 90 Pfam PF12728 Helix-turn-helix domain 33 74 1.2E-7 T 06-07-2017 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 309 6.9E-23 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PIRSF PIRSF037495 1 463 2.0E-159 T 06-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 Gene3D G3DSA:3.50.50.60 6 114 1.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 Gene3D G3DSA:3.50.50.60 263 337 1.2E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 Gene3D G3DSA:3.50.50.60 115 248 3.8E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 Pfam PF04324 BFD-like [2Fe-2S] binding domain 380 431 3.9E-6 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 SUPERFAMILY SSF51905 4 333 2.76E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 9.0E-12 T 06-07-2017 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 9.0E-12 T 06-07-2017 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 9.0E-12 T 06-07-2017 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 111 119 1.6E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.6E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS03460 1e191470b97781ae7bb86772545fa769 463 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 332 1.6E-12 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS20200 92da18313637365bd487f398563af45a 234 SUPERFAMILY SSF53955 14 146 5.63E-17 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS20200 92da18313637365bd487f398563af45a 234 Gene3D G3DSA:1.10.530.10 16 131 5.9E-10 T 06-07-2017 CAL12_RS20200 92da18313637365bd487f398563af45a 234 Pfam PF01464 Transglycosylase SLT domain 7 143 1.7E-15 T 06-07-2017 IPR008258 Transglycosylase SLT domain 1 CAL12_RS20210 690984fca687e46443c6f3970eb4e1c3 130 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 26 106 1.1E-15 T 06-07-2017 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB CAL12_RS06135 482bd292891711102a5f88775a43ef54 230 Pfam PF04268 Sarcosine oxidase, gamma subunit family 71 219 2.9E-28 T 06-07-2017 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CAL12_RS06135 482bd292891711102a5f88775a43ef54 230 SUPERFAMILY SSF103025 102 223 8.83E-13 T 06-07-2017 CAL12_RS17355 185f196c260f417fcaa7d9df8bb16ece 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 2.0E-51 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS20775 7ec6cc5cdb030009a4ce69eb1c20de91 122 Pfam PF07110 EthD domain 16 105 1.9E-14 T 06-07-2017 IPR009799 EthD domain CAL12_RS20775 7ec6cc5cdb030009a4ce69eb1c20de91 122 Gene3D G3DSA:3.30.70.900 4 95 2.5E-17 T 06-07-2017 CAL12_RS20775 7ec6cc5cdb030009a4ce69eb1c20de91 122 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 7 91 6.4E-9 T 06-07-2017 IPR009799 EthD domain CAL12_RS20775 7ec6cc5cdb030009a4ce69eb1c20de91 122 SUPERFAMILY SSF54909 5 115 7.38E-22 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 Gene3D G3DSA:2.30.330.10 245 324 1.2E-5 T 06-07-2017 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 6 321 2.8E-101 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 SUPERFAMILY SSF101801 251 324 3.79E-11 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 1.0E-26 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 1.0E-26 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 1.0E-26 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 1.0E-26 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 322 3.4E-15 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 Pfam PF02154 Flagellar motor switch protein FliM 39 231 2.1E-71 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 PIRSF PIRSF002888 3 331 1.2E-91 T 06-07-2017 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CAL12_RS11990 b598d23d5985d6d6f8954f13623b2d00 335 SUPERFAMILY SSF103039 51 231 8.37E-21 T 06-07-2017 IPR028976 CheC-like domain CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 317 3.5E-20 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 285 1.6E-48 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 Gene3D G3DSA:3.40.50.720 3 120 2.5E-26 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 SUPERFAMILY SSF51735 105 286 2.07E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 SUPERFAMILY SSF52283 1 141 4.54E-28 T 06-07-2017 CAL12_RS13570 2a97baa226803faaff7ae6308cee5f75 317 Gene3D G3DSA:3.40.50.720 121 287 4.1E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03980 ebeb694effa2079d4cebcdbc5a0bc67e 294 Gene3D G3DSA:1.10.3720.10 82 288 2.1E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03980 ebeb694effa2079d4cebcdbc5a0bc67e 294 SUPERFAMILY SSF161098 85 272 3.79E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03980 ebeb694effa2079d4cebcdbc5a0bc67e 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 291 8.1E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 4.5E-50 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 Gene3D G3DSA:3.90.1170.10 22 134 5.1E-54 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 8.5E-42 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 8.5E-42 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 8.5E-42 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 8.5E-42 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.746 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 6.0E-60 T 06-07-2017 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 SUPERFAMILY SSF54686 1 134 8.9E-55 T 06-07-2017 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27620 dd37d76a0a1a5a50d9d596c02fbc2ea7 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 06-07-2017 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 SUPERFAMILY SSF51905 9 191 1.88E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 SUPERFAMILY SSF51905 290 379 1.88E-57 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 SUPERFAMILY SSF54373 196 292 1.31E-21 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 170 185 8.7E-20 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 8.7E-20 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 8.7E-20 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 8.7E-20 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 8.7E-20 T 06-07-2017 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 Gene3D G3DSA:3.50.50.60 290 373 5.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 Gene3D G3DSA:3.50.50.60 9 196 5.7E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16405 12f61982247c3e37524857db007e6bcc 421 Pfam PF01494 FAD binding domain 11 365 2.8E-24 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS15140 bb4f1b89fdb2b512adc3ca48a94ecfa4 280 Gene3D G3DSA:1.10.3720.10 12 273 1.3E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15140 bb4f1b89fdb2b512adc3ca48a94ecfa4 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 267 4.6E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15140 bb4f1b89fdb2b512adc3ca48a94ecfa4 280 SUPERFAMILY SSF161098 9 271 7.85E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23455 b99b5164f5f3309719b68a47b7a0e7b1 392 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 98 348 2.4E-28 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS23455 b99b5164f5f3309719b68a47b7a0e7b1 392 SUPERFAMILY SSF51197 71 355 3.66E-48 T 06-07-2017 CAL12_RS23455 b99b5164f5f3309719b68a47b7a0e7b1 392 Gene3D G3DSA:3.60.130.10 76 356 6.6E-36 T 06-07-2017 CAL12_RS02695 d757f7e60b7f09d9c6578092d64934e8 225 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 65 225 1.1E-39 T 06-07-2017 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS02695 d757f7e60b7f09d9c6578092d64934e8 225 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 25 225 29.735 T 06-07-2017 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS02695 d757f7e60b7f09d9c6578092d64934e8 225 SUPERFAMILY SSF47240 58 139 1.26E-16 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS02695 d757f7e60b7f09d9c6578092d64934e8 225 Gene3D G3DSA:1.20.1260.10 73 191 1.7E-8 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS22785 a4a7d3dcc0751f2a9005cf950e164946 249 SUPERFAMILY SSF88713 10 239 4.73E-43 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS22785 a4a7d3dcc0751f2a9005cf950e164946 249 Gene3D G3DSA:3.20.20.370 11 236 5.4E-43 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS22785 a4a7d3dcc0751f2a9005cf950e164946 249 Pfam PF01522 Polysaccharide deacetylase 14 162 3.8E-20 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS18725 573908a4bbed20d72050793b0054086c 403 SMART SM00729 99 327 2.8E-7 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS18725 573908a4bbed20d72050793b0054086c 403 Gene3D G3DSA:3.20.20.70 185 331 1.7E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS18725 573908a4bbed20d72050793b0054086c 403 Pfam PF04055 Radical SAM superfamily 103 281 5.4E-13 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS18725 573908a4bbed20d72050793b0054086c 403 SUPERFAMILY SSF102114 83 297 3.4E-11 T 06-07-2017 CAL12_RS04660 5ae178ba64925a5562437a3b58cdc90b 406 Gene3D G3DSA:1.10.10.10 334 372 4.3E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04660 5ae178ba64925a5562437a3b58cdc90b 406 SUPERFAMILY SSF46785 329 385 2.35E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23265 646ac546c9cac7f24492ff93c9571da2 330 SUPERFAMILY SSF53850 122 292 3.44E-15 T 06-07-2017 CAL12_RS23265 646ac546c9cac7f24492ff93c9571da2 330 PIRSF PIRSF017082 1 330 9.6E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23265 646ac546c9cac7f24492ff93c9571da2 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 1.3E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 547 2.9E-161 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 PIRSF PIRSF003128 1 548 3.3E-167 T 06-07-2017 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 Gene3D G3DSA:3.40.50.300 426 490 6.7E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 SUPERFAMILY SSF52540 286 493 3.63E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 SUPERFAMILY SSF52540 3 50 3.63E-26 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 505 2.7E-17 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 SUPERFAMILY SSF52540 1 215 8.64E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06210 60aebdb74c2045214e27e8a4f5483c7b 548 Gene3D G3DSA:3.40.50.300 1 204 2.7E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 SMART SM00829 10 323 1.1E-48 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 SUPERFAMILY SSF50129 1 140 1.98E-37 T 06-07-2017 IPR011032 GroES-like CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 2.7E-6 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 4.7E-144 T 06-07-2017 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 SUPERFAMILY SSF51735 111 287 4.05E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 Gene3D G3DSA:3.90.180.10 1 145 7.0E-41 T 06-07-2017 IPR011032 GroES-like CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 Gene3D G3DSA:3.40.50.720 146 262 8.5E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20050 eebc9c8bbd802d9321dfdda24644d8ca 327 Pfam PF00107 Zinc-binding dehydrogenase 151 266 1.9E-28 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 4.4E-5 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 409 428 4.4E-5 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 367 387 4.4E-5 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 4.4E-5 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 433 8.4E-73 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 Gene3D G3DSA:1.20.1250.20 16 203 8.9E-28 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 Gene3D G3DSA:1.20.1250.20 277 459 6.1E-19 T 06-07-2017 CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 SUPERFAMILY SSF103473 20 212 7.85E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 SUPERFAMILY SSF103473 257 459 7.85E-61 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19325 271f7bfda3b257e8dde05f73f277c662 460 Pfam PF07690 Major Facilitator Superfamily 26 418 4.4E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 3.4E-67 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 SUPERFAMILY SSF55103 229 469 4.09E-75 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 Gene3D G3DSA:3.30.465.10 108 226 2.8E-46 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 Gene3D G3DSA:3.30.43.10 11 106 7.5E-31 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 Pfam PF01565 FAD binding domain 52 188 8.2E-41 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 Gene3D G3DSA:1.10.45.10 427 466 7.0E-17 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS17775 fbc212a6a13fd4bc5435f8c4592b9e3c 469 SUPERFAMILY SSF56176 13 226 2.1E-71 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 SUPERFAMILY SSF88659 96 157 7.41E-16 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 156 4.2E-20 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 Pfam PF04542 Sigma-70 region 2 12 73 1.3E-13 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 SUPERFAMILY SSF88946 10 89 1.1E-16 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 Gene3D G3DSA:1.10.10.10 99 158 1.6E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 Pfam PF08281 Sigma-70, region 4 102 152 1.2E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS06840 25c9417522b0388c8153c563ee5f1fd1 172 Gene3D G3DSA:1.10.1740.10 10 75 3.7E-19 T 06-07-2017 CAL12_RS13665 3b6bbcb23fb0ac0fc22674ced59c697d 291 SUPERFAMILY SSF47413 6 67 4.44E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS13665 3b6bbcb23fb0ac0fc22674ced59c697d 291 Gene3D G3DSA:1.10.260.40 7 67 3.3E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS13665 3b6bbcb23fb0ac0fc22674ced59c697d 291 SMART SM00530 11 65 2.7E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS13665 3b6bbcb23fb0ac0fc22674ced59c697d 291 Pfam PF13560 Helix-turn-helix domain 7 63 4.7E-10 T 06-07-2017 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 12 75 1.3E-10 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 Gene3D G3DSA:3.10.20.30 8 80 4.7E-34 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 SUPERFAMILY SSF47741 90 156 2.75E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 SUPERFAMILY SSF54292 8 84 4.98E-28 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 Gene3D G3DSA:1.10.150.120 81 156 9.3E-34 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 45 53 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS24345 eb1521815970b00760a354b6f874c88d 158 Pfam PF01799 [2Fe-2S] binding domain 79 151 7.2E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 PIRSF PIRSF006276 1 149 1.6E-17 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 SUPERFAMILY SSF52402 1 147 1.0E-38 T 06-07-2017 CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 Pfam PF00582 Universal stress protein family 1 146 5.4E-33 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 PRINTS PR01438 Universal stress protein signature 124 146 9.4E-23 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 PRINTS PR01438 Universal stress protein signature 2 20 9.4E-23 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 PRINTS PR01438 Universal stress protein signature 106 118 9.4E-23 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14155 9227f203793b918bbb733bb17d628980 157 Gene3D G3DSA:3.40.50.620 1 148 8.2E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS14330 8095a8d63c39e4a5d6d2fd210e72ec8d 472 SUPERFAMILY SSF81442 13 468 5.36E-123 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14330 8095a8d63c39e4a5d6d2fd210e72ec8d 472 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 206 261 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14330 8095a8d63c39e4a5d6d2fd210e72ec8d 472 Gene3D G3DSA:1.20.210.10 16 468 9.3E-71 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14330 8095a8d63c39e4a5d6d2fd210e72ec8d 472 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 11 466 1.2E-229 T 06-07-2017 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAL12_RS14330 8095a8d63c39e4a5d6d2fd210e72ec8d 472 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 16 446 1.3E-114 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 SUPERFAMILY SSF56059 482 691 4.52E-29 T 06-07-2017 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 SMART SM00881 13 108 4.8E-22 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 Pfam PF13380 CoA binding domain 17 140 3.2E-18 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 SUPERFAMILY SSF52210 314 459 8.37E-17 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 Pfam PF13549 ATP-grasp domain 481 689 1.6E-53 T 06-07-2017 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 SUPERFAMILY SSF52210 156 304 3.66E-36 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 SUPERFAMILY SSF51735 6 146 2.67E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 163 298 5.0E-46 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 Gene3D G3DSA:3.40.50.261 139 298 1.3E-25 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS27955 d2f61dfc1667938a4a23df404b335146 692 Gene3D G3DSA:3.40.50.720 8 138 1.8E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11780 8a8632aaa47c147365af0c7ccd0f45a5 256 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 3.3E-144 T 06-07-2017 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 CAL12_RS11780 8a8632aaa47c147365af0c7ccd0f45a5 256 Gene3D G3DSA:3.90.550.10 1 255 1.3E-63 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS11780 8a8632aaa47c147365af0c7ccd0f45a5 256 Pfam PF00483 Nucleotidyl transferase 2 200 2.1E-17 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAL12_RS11780 8a8632aaa47c147365af0c7ccd0f45a5 256 SUPERFAMILY SSF53448 1 256 1.64E-67 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS21970 c11744a3272dc03e58dd8440910b71af 124 Pfam PF12643 MazG-like family 39 121 1.3E-17 T 06-07-2017 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CAL12_RS21970 c11744a3272dc03e58dd8440910b71af 124 PIRSF PIRSF029826 1 121 3.3E-45 T 06-07-2017 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 CAL12_RS21970 c11744a3272dc03e58dd8440910b71af 124 SUPERFAMILY SSF101386 12 120 6.21E-34 T 06-07-2017 CAL12_RS21970 c11744a3272dc03e58dd8440910b71af 124 Gene3D G3DSA:1.10.287.1080 3 99 1.1E-25 T 06-07-2017 CAL12_RS05450 70ba074ff7978d9af86161c6b829c18c 307 Gene3D G3DSA:3.40.1190.20 1 306 1.2E-82 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS05450 70ba074ff7978d9af86161c6b829c18c 307 Pfam PF00294 pfkB family carbohydrate kinase 11 297 8.5E-53 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAL12_RS05450 70ba074ff7978d9af86161c6b829c18c 307 SUPERFAMILY SSF53613 1 305 1.06E-76 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 Gene3D G3DSA:3.40.50.620 50 210 1.4E-41 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 PRINTS PR01438 Universal stress protein signature 63 81 1.6E-20 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 PRINTS PR01438 Universal stress protein signature 167 179 1.6E-20 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 PRINTS PR01438 Universal stress protein signature 185 207 1.6E-20 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 SUPERFAMILY SSF52402 62 208 2.6E-38 T 06-07-2017 CAL12_RS14385 629a9678cb9f36e9368114f5d0e2e248 216 Pfam PF00582 Universal stress protein family 62 207 2.7E-35 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 SUPERFAMILY SSF46689 21 90 9.75E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.3E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 Gene3D G3DSA:1.10.357.10 26 207 1.1E-28 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 1.1E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS09430 f2a3f7c06c20939b71721573e2edbeeb 211 SUPERFAMILY SSF48498 96 204 3.92E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 Gene3D G3DSA:1.10.230.10 123 221 3.4E-13 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 SUPERFAMILY SSF48256 7 267 2.75E-54 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 Pfam PF00285 Citrate synthase, C-terminal domain 58 251 1.4E-29 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 Pfam PF00285 Citrate synthase, C-terminal domain 17 62 2.0E-6 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 Gene3D G3DSA:1.10.580.10 62 122 4.8E-10 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS24165 b253c67cc30e3651199ceeca2213e648 283 Gene3D G3DSA:1.10.580.10 18 61 1.0E-8 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS18320 f71849ce679c2083672c1b5ffcd2abad 100 Gene3D G3DSA:1.10.10.10 2 97 3.0E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18320 f71849ce679c2083672c1b5ffcd2abad 100 Pfam PF12840 Helix-turn-helix domain 5 78 5.8E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18320 f71849ce679c2083672c1b5ffcd2abad 100 SMART SM00418 5 98 2.6E-12 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS18320 f71849ce679c2083672c1b5ffcd2abad 100 SUPERFAMILY SSF46785 2 96 1.06E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 Pfam PF07690 Major Facilitator Superfamily 20 412 2.0E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 Gene3D G3DSA:1.20.1250.20 15 197 2.7E-30 T 06-07-2017 CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 Gene3D G3DSA:1.20.1250.20 271 423 1.9E-18 T 06-07-2017 CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 Gene3D G3DSA:1.20.1250.20 480 504 1.9E-18 T 06-07-2017 CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 499 2.9E-81 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 SUPERFAMILY SSF103473 10 198 4.45E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 SUPERFAMILY SSF103473 250 422 4.45E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS20490 cf2fc1f022c4f9bf8899554fd9a504c6 510 SUPERFAMILY SSF103473 479 503 4.45E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 Gene3D G3DSA:1.10.10.10 4 85 9.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 SUPERFAMILY SSF46785 4 111 3.15E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 Pfam PF03466 LysR substrate binding domain 88 292 3.0E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 SUPERFAMILY SSF53850 90 297 1.48E-48 T 06-07-2017 CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 Gene3D G3DSA:3.40.190.10 92 177 2.0E-27 T 06-07-2017 CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09025 b922ce1cfb3145afaf645fb45d0fa68b 305 Gene3D G3DSA:3.40.190.10 178 260 3.4E-4 T 06-07-2017 CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 Gene3D G3DSA:3.90.25.10 212 233 7.6E-11 T 06-07-2017 CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 Gene3D G3DSA:3.90.25.10 286 309 7.6E-11 T 06-07-2017 CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 239 9.0E-78 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 SUPERFAMILY SSF51735 7 308 3.16E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 5 307 48.663 T 06-07-2017 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|Reactome: R-HSA-6787639 CAL12_RS07990 62e04287bf75250e6337582de805abd6 317 Gene3D G3DSA:3.40.50.720 6 211 3.4E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18235 b50f385f5dea0e0cc5f41667bfe1a996 151 Gene3D G3DSA:3.40.1230.10 1 146 1.1E-42 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAL12_RS18235 b50f385f5dea0e0cc5f41667bfe1a996 151 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 144 1.6E-32 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAL12_RS18235 b50f385f5dea0e0cc5f41667bfe1a996 151 SUPERFAMILY SSF64076 2 146 1.18E-31 T 06-07-2017 IPR007523 NDUFAF3/Mth938 domain-containing protein CAL12_RS26765 f884ec89076d5cd212db3bcefb27199b 219 Pfam PF06912 Protein of unknown function (DUF1275) 7 204 7.3E-31 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAL12_RS10215 4a86786ca4c7501f36fe2f176272c082 188 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 20 87 2.0E-10 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS10215 4a86786ca4c7501f36fe2f176272c082 188 Gene3D G3DSA:3.90.470.20 21 130 8.9E-16 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS10215 4a86786ca4c7501f36fe2f176272c082 188 SUPERFAMILY SSF56214 20 133 1.4E-16 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 4 340 1.5E-126 T 06-07-2017 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 329 1.9E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 Gene3D G3DSA:3.90.25.10 269 342 3.2E-49 T 06-07-2017 CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 Gene3D G3DSA:3.90.25.10 186 237 3.2E-49 T 06-07-2017 CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 SUPERFAMILY SSF51735 1 340 2.68E-91 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08030 68a6e8f59dffd159749ec1a41bdd1521 345 Gene3D G3DSA:3.40.50.720 2 185 3.2E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22965 5e9dd33cc67bc4002ce63057c3ae074a 429 Pfam PF13439 Glycosyltransferase Family 4 23 200 1.9E-33 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS22965 5e9dd33cc67bc4002ce63057c3ae074a 429 Pfam PF00534 Glycosyl transferases group 1 209 385 7.4E-41 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS22965 5e9dd33cc67bc4002ce63057c3ae074a 429 Gene3D G3DSA:3.40.50.2000 182 386 5.7E-38 T 06-07-2017 CAL12_RS22965 5e9dd33cc67bc4002ce63057c3ae074a 429 SUPERFAMILY SSF53756 19 408 1.35E-92 T 06-07-2017 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 Gene3D G3DSA:3.40.640.10 42 257 2.1E-56 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 10 360 53.429 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 Pfam PF00155 Aminotransferase class I and II 28 353 1.5E-44 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 Gene3D G3DSA:3.90.1150.10 258 360 1.6E-21 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 12 359 1.5E-91 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS00835 9419291a204e19bd36ea0e91b9eb55e8 361 SUPERFAMILY SSF53383 14 360 1.9E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 9 469 34.074 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 SUPERFAMILY SSF52374 9 305 4.56E-113 T 06-07-2017 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 4.6E-27 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 4.6E-27 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 4.6E-27 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 205 213 4.6E-27 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 PRINTS PR00987 Glutamyl-tRNA synthetase signature 189 199 4.6E-27 T 06-07-2017 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Gene3D G3DSA:1.10.10.350 383 469 4.1E-24 T 06-07-2017 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 SUPERFAMILY SSF48163 309 469 3.14E-38 T 06-07-2017 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Gene3D G3DSA:3.90.800.10 74 190 1.7E-36 T 06-07-2017 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Gene3D G3DSA:3.40.50.620 9 73 2.5E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Gene3D G3DSA:3.40.50.620 191 240 2.5E-53 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 467 1.4E-164 T 06-07-2017 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Gene3D G3DSA:1.10.1160.10 243 324 1.7E-35 T 06-07-2017 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CAL12_RS24800 4556021db7d7bc2463ea5d4241cfeb05 470 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 315 2.1E-105 T 06-07-2017 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 SUPERFAMILY SSF58104 236 517 2.22E-65 T 06-07-2017 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 Pfam PF00672 HAMP domain 198 263 1.1E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 Gene3D G3DSA:1.10.287.950 290 488 5.7E-51 T 06-07-2017 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 515 5.4E-51 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 1.7E-44 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.7E-44 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 1.7E-44 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 1.7E-44 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 1.7E-44 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 SMART SM00304 216 268 4.2E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 Pfam PF02203 Tar ligand binding domain homologue 1 173 9.2E-18 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS15340 843b0a3960fc1e800015e11cfee4f2a7 564 SMART SM00283 269 516 3.5E-71 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 SUPERFAMILY SSF53850 36 266 1.15E-53 T 06-07-2017 CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 Gene3D G3DSA:3.40.190.10 121 204 9.8E-16 T 06-07-2017 CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 261 1.3E-45 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 Gene3D G3DSA:3.40.190.10 41 120 1.9E-34 T 06-07-2017 CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 Gene3D G3DSA:3.40.190.10 221 263 1.9E-34 T 06-07-2017 CAL12_RS13660 0630d3c8affc10e7317149bfd379d49b 273 SMART SM00062 44 262 7.2E-43 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 Gene3D G3DSA:3.40.640.10 95 335 7.3E-32 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 488 229.151 T 06-07-2017 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 SUPERFAMILY SSF53383 94 392 2.01E-42 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 Pfam PF12390 Selenocysteine synthase N terminal 27 64 3.6E-7 T 06-07-2017 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 Pfam PF03841 L-seryl-tRNA selenium transferase 101 471 5.6E-159 T 06-07-2017 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CAL12_RS19450 4a8140ed1ee90d8c1c371a4238a85161 488 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 26 484 1.4E-178 T 06-07-2017 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CAL12_RS05955 d44cbde7b6a2513e5179a7298288aa67 346 SUPERFAMILY SSF53850 134 304 2.39E-8 T 06-07-2017 CAL12_RS05955 d44cbde7b6a2513e5179a7298288aa67 346 PIRSF PIRSF017082 21 345 2.8E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05955 d44cbde7b6a2513e5179a7298288aa67 346 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 341 5.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 SUPERFAMILY SSF51735 142 309 3.04E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 Gene3D G3DSA:3.90.180.10 2 172 5.9E-68 T 06-07-2017 IPR011032 GroES-like CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 Gene3D G3DSA:3.40.50.720 173 288 1.2E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 135 6.4E-33 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 Pfam PF00107 Zinc-binding dehydrogenase 179 302 8.1E-27 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 SUPERFAMILY SSF50129 310 338 1.26E-57 T 06-07-2017 IPR011032 GroES-like CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 SUPERFAMILY SSF50129 2 146 1.26E-57 T 06-07-2017 IPR011032 GroES-like CAL12_RS21225 e0fb8722c40aecb46a26530c99aa314d 342 SMART SM00829 14 338 8.8E-8 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS24040 d238a85d0e462894613e2ca8076b8b0c 349 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 51 324 2.6E-59 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS24040 d238a85d0e462894613e2ca8076b8b0c 349 PIRSF PIRSF006470 13 344 2.0E-66 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 Pfam PF03704 Bacterial transcriptional activator domain 195 312 3.9E-12 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 SMART SM01043 178 317 3.2E-8 T 06-07-2017 IPR005158 Bacterial transcriptional activator domain CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 SUPERFAMILY SSF48452 214 331 4.09E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 Pfam PF13191 AAA ATPase domain 500 692 8.2E-19 T 06-07-2017 CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 SUPERFAMILY SSF52540 496 561 2.83E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 SUPERFAMILY SSF52540 658 760 2.83E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 SUPERFAMILY SSF46894 83 158 8.22E-7 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 Gene3D G3DSA:1.25.40.10 234 296 7.1E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22175 941eeed3fd7a007c4f38d2f545297f99 805 Gene3D G3DSA:3.40.50.300 497 566 4.0E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07555 4e55303c7889059fa87c6e446faf82f5 189 Gene3D G3DSA:3.30.70.900 14 101 2.7E-14 T 06-07-2017 CAL12_RS07555 4e55303c7889059fa87c6e446faf82f5 189 SUPERFAMILY SSF54909 9 111 2.15E-18 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS20845 d00d0e8489ec48697b42f250f8a52a05 333 SUPERFAMILY SSF53850 121 294 4.44E-10 T 06-07-2017 CAL12_RS20845 d00d0e8489ec48697b42f250f8a52a05 333 PIRSF PIRSF017082 1 333 4.1E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20845 d00d0e8489ec48697b42f250f8a52a05 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 330 3.5E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 SMART SM00062 54 273 8.4E-61 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 Gene3D G3DSA:3.40.190.10 133 227 1.6E-19 T 06-07-2017 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 55 271 3.0E-57 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 77 90 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 Gene3D G3DSA:3.40.190.10 51 132 6.6E-34 T 06-07-2017 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 Gene3D G3DSA:3.40.190.10 232 272 6.6E-34 T 06-07-2017 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 SMART SM00079 54 272 0.0045 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAL12_RS21155 58ffaba53e9a6d933227f745d0977ed0 282 SUPERFAMILY SSF53850 44 272 2.36E-62 T 06-07-2017 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 396 50.539 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 PIRSF PIRSF001413 1 399 5.2E-158 T 06-07-2017 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 06-07-2017 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 Gene3D G3DSA:3.40.50.1100 104 182 6.4E-22 T 06-07-2017 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 SUPERFAMILY SSF53686 8 394 6.81E-145 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 Gene3D G3DSA:3.40.50.1100 183 396 4.9E-94 T 06-07-2017 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 395 1.8E-185 T 06-07-2017 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CAL12_RS08260 724c55dee217b6c18e4a43fa75cf4f54 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 383 1.6E-48 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 Gene3D G3DSA:1.10.1040.10 165 283 3.8E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 PIRSF PIRSF000103 1 288 3.9E-74 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 SUPERFAMILY SSF51735 1 161 1.08E-37 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 Gene3D G3DSA:3.40.50.720 1 160 9.0E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 SUPERFAMILY SSF48179 165 283 3.4E-23 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 159 7.9E-35 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS18595 a93aab92bb19673df0134efbb1cbf1d4 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 278 2.9E-15 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS12785 ad22883fea95cde8dbdce7b2ff9c0ae1 244 Pfam PF01144 Coenzyme A transferase 15 171 5.2E-14 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS12785 ad22883fea95cde8dbdce7b2ff9c0ae1 244 SMART SM00882 9 202 3.0E-8 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS12785 ad22883fea95cde8dbdce7b2ff9c0ae1 244 Gene3D G3DSA:3.40.810.20 8 237 9.6E-61 T 06-07-2017 CAL12_RS12785 ad22883fea95cde8dbdce7b2ff9c0ae1 244 SUPERFAMILY SSF100950 4 233 6.58E-50 T 06-07-2017 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 Gene3D G3DSA:1.10.10.10 3 82 2.3E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 Gene3D G3DSA:3.40.190.10 96 177 5.4E-29 T 06-07-2017 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 Pfam PF03466 LysR substrate binding domain 95 292 6.5E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 Gene3D G3DSA:3.40.190.10 178 258 1.1E-28 T 06-07-2017 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 SUPERFAMILY SSF46785 4 82 2.18E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 SUPERFAMILY SSF53850 96 295 1.63E-33 T 06-07-2017 CAL12_RS15450 1341dfb69449dbe1829e2d355f3ab328 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 9.8E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 342 5.1E-19 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 SMART SM00833 252 344 1.4E-20 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 193 8.2E-48 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 Gene3D G3DSA:3.30.1220.10 247 343 1.4E-21 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 SUPERFAMILY SSF52540 11 203 5.34E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 SUPERFAMILY SSF90002 252 342 6.41E-19 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS06965 54cd064c32a13bc8d3ad1057e6eb4404 348 Gene3D G3DSA:3.40.50.300 11 211 9.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05445 7155fb572f8be4b266dab6a22fdf105f 219 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 16 214 5.4E-51 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAL12_RS05445 7155fb572f8be4b266dab6a22fdf105f 219 Pfam PF01081 KDPG and KHG aldolase 17 203 3.4E-40 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAL12_RS05445 7155fb572f8be4b266dab6a22fdf105f 219 SUPERFAMILY SSF51569 15 214 1.14E-56 T 06-07-2017 CAL12_RS05445 7155fb572f8be4b266dab6a22fdf105f 219 Gene3D G3DSA:3.20.20.70 16 217 1.3E-64 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS03720 d56dac7d2c1797aaac9611e1fd73c3e0 182 SUPERFAMILY SSF51261 36 172 2.88E-32 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS03720 d56dac7d2c1797aaac9611e1fd73c3e0 182 Gene3D G3DSA:2.70.70.10 41 173 2.2E-32 T 06-07-2017 CAL12_RS03720 d56dac7d2c1797aaac9611e1fd73c3e0 182 Pfam PF01551 Peptidase family M23 71 168 7.3E-24 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS03795 8af313fb1f21f23bc2e80b2ee8da4f31 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 290 1.1E-46 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS03795 8af313fb1f21f23bc2e80b2ee8da4f31 305 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 13 304 3.9E-119 T 06-07-2017 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CAL12_RS08155 e4a6aab4810f62fca21cde8f689b8454 400 Pfam PF11062 Protein of unknown function (DUF2863) 5 399 4.3E-174 T 06-07-2017 IPR021292 Protein of unknown function DUF2863 CAL12_RS03840 74e6f1453391a702c7c3683c97fc47e9 472 Pfam PF01425 Amidase 25 453 2.5E-95 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS03840 74e6f1453391a702c7c3683c97fc47e9 472 SUPERFAMILY SSF75304 2 470 2.09E-125 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS03840 74e6f1453391a702c7c3683c97fc47e9 472 Gene3D G3DSA:3.90.1300.10 2 470 4.8E-124 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23705 b7d3317d2e64c1af424222dc82fc271c 434 SUPERFAMILY SSF51126 144 433 2.23E-7 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23705 b7d3317d2e64c1af424222dc82fc271c 434 Pfam PF12951 Passenger-associated-transport-repeat 406 433 4.7E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23705 b7d3317d2e64c1af424222dc82fc271c 434 Gene3D G3DSA:2.160.20.20 366 433 9.6E-7 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23705 b7d3317d2e64c1af424222dc82fc271c 434 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 405 433 2.7E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 Pfam PF13378 Enolase C-terminal domain-like 149 352 2.5E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 Gene3D G3DSA:3.20.20.120 130 351 9.5E-80 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 SMART SM00922 146 243 6.5E-29 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 Gene3D G3DSA:3.30.390.10 1 129 5.0E-34 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 SUPERFAMILY SSF51604 114 357 3.54E-79 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 SUPERFAMILY SSF54826 1 128 1.93E-30 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00380 dec698b88b5d090e563d451e893e2559 363 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 126 9.1E-17 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 24 199 2.0E-64 T 06-07-2017 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 158 170 6.0E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 144 6.0E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 PRINTS PR00162 Rieske 2Fe-2S subunit signature 171 183 6.0E-7 T 06-07-2017 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 Gene3D G3DSA:2.102.10.10 26 203 1.4E-41 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 SUPERFAMILY SSF50022 43 202 2.36E-39 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS00760 ede7cbcd6d0a2b5107ef388c49d3ba95 206 Pfam PF00355 Rieske [2Fe-2S] domain 68 186 4.3E-13 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 SUPERFAMILY SSF46785 2 110 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 SUPERFAMILY SSF53850 88 296 8.69E-29 T 06-07-2017 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 Gene3D G3DSA:1.10.10.10 2 87 6.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 Gene3D G3DSA:3.40.190.10 88 180 9.8E-15 T 06-07-2017 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 Gene3D G3DSA:3.40.190.10 181 261 9.1E-5 T 06-07-2017 CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 Pfam PF03466 LysR substrate binding domain 87 290 1.5E-26 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02145 9bcfaa1d323e14339fd504a18b191553 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 SUPERFAMILY SSF51735 3 244 6.53E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.2E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 4.2E-116 T 06-07-2017 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216 CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 Gene3D G3DSA:3.40.50.720 1 244 5.2E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 Pfam PF00106 short chain dehydrogenase 4 196 1.6E-61 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19165 dd7ad7ab2eada4be2bd86510546f1d34 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 8.3E-4 T 06-07-2017 CAL12_RS26225 5366af7ecdad2496d67d6f3cf27f47ed 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 30.604 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAL12_RS26225 5366af7ecdad2496d67d6f3cf27f47ed 156 SUPERFAMILY SSF75217 2 153 4.97E-40 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS26225 5366af7ecdad2496d67d6f3cf27f47ed 156 Gene3D G3DSA:3.40.1280.10 1 155 4.1E-59 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS26225 5366af7ecdad2496d67d6f3cf27f47ed 156 Pfam PF00588 SpoU rRNA Methylase family 3 143 4.3E-30 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAL12_RS26225 5366af7ecdad2496d67d6f3cf27f47ed 156 PIRSF PIRSF029256 1 155 1.2E-56 T 06-07-2017 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 Gene3D G3DSA:1.10.357.10 65 205 1.0E-22 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 SUPERFAMILY SSF48498 92 191 1.58E-21 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 Pfam PF09209 Domain of unknown function (DUF1956) 97 213 8.0E-23 T 06-07-2017 IPR015292 Transcription regulator YbiH, C-terminal CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 SUPERFAMILY SSF46689 14 84 1.54E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.9E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 Gene3D G3DSA:1.10.10.60 14 64 4.1E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS02915 3e91bb412c4b9fec2540118f1441c0d4 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 2.2E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 SUPERFAMILY SSF51126 2 116 2.51E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 Pfam PF12951 Passenger-associated-transport-repeat 88 116 8.9E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 Pfam PF12951 Passenger-associated-transport-repeat 1 30 3.2E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 Gene3D G3DSA:2.160.20.20 1 116 7.4E-14 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 1 31 1.9E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23635 7e732ef967af2d98c48999ca676ec0c0 116 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 89 116 2.1E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05870 f9148e8f71f3a450b2b62103b8074f13 260 Pfam PF00005 ABC transporter 23 162 2.3E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05870 f9148e8f71f3a450b2b62103b8074f13 260 Gene3D G3DSA:3.40.50.300 3 219 1.7E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05870 f9148e8f71f3a450b2b62103b8074f13 260 SMART SM00382 32 213 1.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05870 f9148e8f71f3a450b2b62103b8074f13 260 SUPERFAMILY SSF52540 4 237 1.13E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05870 f9148e8f71f3a450b2b62103b8074f13 260 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS20250 571214e96092fa3a797aba08336b18c9 387 Pfam PF03743 Bacterial conjugation TrbI-like protein 200 376 1.7E-44 T 06-07-2017 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.0E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 3.0E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 3.0E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 3.0E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 3.0E-32 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 1.0E-44 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 45.882 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 2.1E-48 T 06-07-2017 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 06-07-2017 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 Gene3D G3DSA:3.30.420.10 1 153 2.8E-59 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS05585 f8c5eab5d0d3313b5a9314edc194fc89 183 SUPERFAMILY SSF53098 1 154 1.85E-49 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS18175 f4b02c18cd4b27c6fb80a98734a2799e 372 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 97 367 1.0E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18175 f4b02c18cd4b27c6fb80a98734a2799e 372 PIRSF PIRSF017082 45 372 3.7E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18175 f4b02c18cd4b27c6fb80a98734a2799e 372 SUPERFAMILY SSF53850 162 333 1.77E-10 T 06-07-2017 CAL12_RS01210 a873a241add78b2c32bcbbda97edd1b2 88 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 75 4.3E-14 T 06-07-2017 CAL12_RS01210 a873a241add78b2c32bcbbda97edd1b2 88 SUPERFAMILY SSF54292 4 71 2.1E-14 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS01210 a873a241add78b2c32bcbbda97edd1b2 88 Gene3D G3DSA:3.10.20.30 10 70 1.4E-8 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 SUPERFAMILY SSF52402 5 231 2.87E-53 T 06-07-2017 CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 PIRSF PIRSF006293 4 238 3.9E-66 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 Gene3D G3DSA:3.40.50.620 6 230 3.5E-73 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 237 51.668 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 224 1.1E-58 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAL12_RS01880 b4864d5edb48f1144fb4d1fbf828cb20 242 Pfam PF06508 Queuosine biosynthesis protein QueC 7 231 2.8E-70 T 06-07-2017 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CAL12_RS16245 4f7dcaa1b60703d9c85991ae1f62fddd 349 Pfam PF17186 Lipocalin-like domain 220 349 2.2E-40 T 06-07-2017 IPR033451 AttH, lipocalin-like domain CAL12_RS16245 4f7dcaa1b60703d9c85991ae1f62fddd 349 Pfam PF07143 CrtC N-terminal lipocalin domain 50 217 8.1E-57 T 06-07-2017 IPR010791 AttH domain CAL12_RS16245 4f7dcaa1b60703d9c85991ae1f62fddd 349 Gene3D G3DSA:2.40.370.10 223 349 1.1E-41 T 06-07-2017 IPR023374 AttH-like domain CAL12_RS16245 4f7dcaa1b60703d9c85991ae1f62fddd 349 SUPERFAMILY SSF159245 27 349 4.32E-107 T 06-07-2017 CAL12_RS16245 4f7dcaa1b60703d9c85991ae1f62fddd 349 Gene3D G3DSA:2.40.370.10 38 219 4.3E-73 T 06-07-2017 IPR023374 AttH-like domain CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 624 1.8E-28 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Pfam PF00501 AMP-binding enzyme 91 534 2.4E-93 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Gene3D G3DSA:3.40.50.980 274 438 1.5E-27 T 06-07-2017 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Gene3D G3DSA:2.30.38.10 451 528 8.0E-12 T 06-07-2017 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 88 1.1E-20 T 06-07-2017 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 SUPERFAMILY SSF56801 16 655 1.96E-175 T 06-07-2017 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Gene3D G3DSA:3.40.50.980 87 273 3.8E-38 T 06-07-2017 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Gene3D G3DSA:3.30.300.30 529 637 7.9E-28 T 06-07-2017 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 659 51.866 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 29 657 2.6E-297 T 06-07-2017 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: R-HSA-71384 CAL12_RS08540 5b42f0cfe6da76d76a8a8f5739c69609 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS16850 b613211aa7d6a165dfd22d6d1f26a4b9 325 SUPERFAMILY SSF52096 66 324 7.05E-57 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16850 b613211aa7d6a165dfd22d6d1f26a4b9 325 Gene3D G3DSA:3.90.226.10 62 318 2.7E-52 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16850 b613211aa7d6a165dfd22d6d1f26a4b9 325 Pfam PF00378 Enoyl-CoA hydratase/isomerase 77 323 4.5E-34 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS22080 d2d0aa32406dec22fd3a13aada395c75 224 TIGRFAM TIGR02499 HrpE_YscL_not: type III secretion apparatus protein, HrpE/YscL family 23 191 9.2E-33 T 06-07-2017 IPR012842 Type III secretion system HrpE/YscL CAL12_RS22080 d2d0aa32406dec22fd3a13aada395c75 224 Pfam PF02108 Flagellar assembly protein FliH 74 197 3.3E-12 T 06-07-2017 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CAL12_RS24605 94d69fc6a3263a716e552f10ea3e10f9 264 Gene3D G3DSA:1.10.230.10 113 207 3.2E-11 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS24605 94d69fc6a3263a716e552f10ea3e10f9 264 Pfam PF00285 Citrate synthase, C-terminal domain 42 240 1.7E-23 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24605 94d69fc6a3263a716e552f10ea3e10f9 264 SUPERFAMILY SSF48256 10 245 5.36E-44 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24605 94d69fc6a3263a716e552f10ea3e10f9 264 Gene3D G3DSA:1.10.580.10 43 112 7.4E-5 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 SUPERFAMILY SSF54747 3 73 2.22E-30 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 SMART SM00649 9 141 5.2E-85 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 Gene3D G3DSA:3.30.1550.10 2 72 6.1E-37 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 SUPERFAMILY SSF46906 68 141 1.7E-26 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.9E-64 T 06-07-2017 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.0E-25 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 06-07-2017 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 06-07-2017 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.7E-29 T 06-07-2017 IPR020784 Ribosomal protein L11, N-terminal CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 Gene3D G3DSA:1.10.10.250 73 141 1.6E-31 T 06-07-2017 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CAL12_RS27770 9a0e9745c5e5db2a2b1e7267d99aa214 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.548 T 06-07-2017 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 SUPERFAMILY SSF81648 355 448 5.67E-17 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 SUPERFAMILY SSF81342 14 288 3.77E-97 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 Gene3D G3DSA:1.20.810.10 13 332 4.0E-139 T 06-07-2017 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 Pfam PF00033 Cytochrome b/b6/petB 31 219 2.5E-68 T 06-07-2017 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 434 5.1E-41 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 SUPERFAMILY SSF81648 290 331 1.02E-8 T 06-07-2017 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CAL12_RS00755 dca67ff253e8adc33829cf75cc1de4eb 462 Gene3D G3DSA:1.10.287.980 359 428 1.0E-28 T 06-07-2017 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 SUPERFAMILY SSF52954 329 421 2.57E-20 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 PIRSF PIRSF001549 4 422 1.1E-112 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Gene3D G3DSA:3.30.930.10 6 188 1.6E-89 T 06-07-2017 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Gene3D G3DSA:3.30.930.10 224 320 1.6E-89 T 06-07-2017 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Pfam PF03129 Anticodon binding domain 333 421 4.0E-12 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Gene3D G3DSA:3.40.50.800 330 421 4.1E-30 T 06-07-2017 IPR004154 Anticodon-binding CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 6 422 32.224 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 Pfam PF13393 Histidyl-tRNA synthetase 13 315 8.3E-46 T 06-07-2017 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 10 412 1.7E-149 T 06-07-2017 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CAL12_RS09225 9ec5495403b59b179b8855dcc1fd7a7d 422 SUPERFAMILY SSF55681 10 319 3.25E-98 T 06-07-2017 CAL12_RS13850 d3e8b34899d80d4a15ce486daa60f7a7 208 Gene3D G3DSA:1.20.950.20 20 208 1.0E-45 T 06-07-2017 CAL12_RS13850 d3e8b34899d80d4a15ce486daa60f7a7 208 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 21 44 4.9E-6 T 06-07-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CAL12_RS13850 d3e8b34899d80d4a15ce486daa60f7a7 208 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 173 195 4.9E-6 T 06-07-2017 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0006810|GO:0009055|GO:0016020 CAL12_RS13850 d3e8b34899d80d4a15ce486daa60f7a7 208 Pfam PF01292 Prokaryotic cytochrome b561 19 207 6.8E-26 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS13850 d3e8b34899d80d4a15ce486daa60f7a7 208 SUPERFAMILY SSF81342 17 208 3.45E-38 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 Gene3D G3DSA:1.10.1040.10 173 296 1.2E-35 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 171 292 3.9E-38 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 PIRSF PIRSF000103 1 300 1.0E-65 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 SUPERFAMILY SSF48179 171 297 3.74E-30 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 8 165 3.6E-39 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 Gene3D G3DSA:3.40.50.720 4 172 3.4E-45 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07890 e289165075eb0053b0a87ac8f96f4e1e 301 SUPERFAMILY SSF51735 7 169 6.84E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03945 6d73645060ab2258f12943b15c846d40 333 Gene3D G3DSA:3.40.50.1820 66 328 8.0E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03945 6d73645060ab2258f12943b15c846d40 333 SUPERFAMILY SSF53474 65 328 6.19E-54 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03945 6d73645060ab2258f12943b15c846d40 333 Pfam PF07859 alpha/beta hydrolase fold 92 307 3.3E-47 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS10160 1d21cf1597c8459e190df22c45671f5f 777 SUPERFAMILY SSF82866 194 410 4.84E-14 T 06-07-2017 CAL12_RS10160 1d21cf1597c8459e190df22c45671f5f 777 Gene3D G3DSA:1.20.1640.10 222 402 1.1E-8 T 06-07-2017 CAL12_RS10160 1d21cf1597c8459e190df22c45671f5f 777 Gene3D G3DSA:1.20.1640.10 620 773 4.2E-13 T 06-07-2017 CAL12_RS10160 1d21cf1597c8459e190df22c45671f5f 777 SUPERFAMILY SSF82866 624 774 5.89E-18 T 06-07-2017 CAL12_RS10925 f62b23035f760f28996232ebd3a2a002 410 Pfam PF00999 Sodium/hydrogen exchanger family 14 386 3.6E-77 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS24970 bb7fc8a4fa717093191e09f648d9b9d5 260 SUPERFAMILY SSF53613 1 256 2.34E-33 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS24970 bb7fc8a4fa717093191e09f648d9b9d5 260 Gene3D G3DSA:3.40.1190.20 6 256 2.3E-43 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS24970 bb7fc8a4fa717093191e09f648d9b9d5 260 Pfam PF08543 Phosphomethylpyrimidine kinase 7 250 2.8E-35 T 06-07-2017 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-964975 CAL12_RS19265 429362ff1b577e85118f26159cd0bccd 127 Gene3D G3DSA:1.20.1300.10 11 126 1.4E-31 T 06-07-2017 CAL12_RS19265 429362ff1b577e85118f26159cd0bccd 127 SUPERFAMILY SSF81343 11 127 8.72E-26 T 06-07-2017 CAL12_RS19265 429362ff1b577e85118f26159cd0bccd 127 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 16 125 1.7E-35 T 06-07-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CAL12_RS19265 429362ff1b577e85118f26159cd0bccd 127 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 114 1.6E-13 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19265 429362ff1b577e85118f26159cd0bccd 127 PIRSF PIRSF000169 8 127 6.7E-38 T 06-07-2017 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 Gene3D G3DSA:3.10.105.10 311 503 1.6E-52 T 06-07-2017 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 SUPERFAMILY SSF53850 29 516 2.53E-123 T 06-07-2017 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 Gene3D G3DSA:3.40.190.10 192 310 2.7E-32 T 06-07-2017 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 PIRSF PIRSF002741 1 528 1.4E-93 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 Gene3D G3DSA:3.90.76.10 43 191 5.2E-35 T 06-07-2017 CAL12_RS03725 37baa0f995a35f022deafb1e145e280f 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 447 3.9E-80 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 SUPERFAMILY SSF53850 91 301 4.71E-32 T 06-07-2017 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 Gene3D G3DSA:1.10.10.10 4 83 1.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.9E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 SUPERFAMILY SSF46785 2 86 3.59E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 Gene3D G3DSA:3.40.190.10 84 207 3.4E-20 T 06-07-2017 CAL12_RS11270 0cff3b0c5f0d31bc0684dcf89110ce51 334 Pfam PF03466 LysR substrate binding domain 90 296 1.8E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 1.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 1.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 176 195 1.0E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 163 191 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 Gene3D G3DSA:3.40.50.720 29 272 1.3E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 195 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 233 253 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 30 47 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 6.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 35 270 2.3E-61 T 06-07-2017 CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 29 198 5.8E-4 T 06-07-2017 CAL12_RS11205 96fa157344fc4ed113d54374428e4aa3 277 SUPERFAMILY SSF51735 30 271 4.41E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 Pfam PF03466 LysR substrate binding domain 88 281 3.2E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 Gene3D G3DSA:3.40.190.10 91 172 1.6E-14 T 06-07-2017 CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 SUPERFAMILY SSF53850 88 284 1.23E-30 T 06-07-2017 CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 SUPERFAMILY SSF46785 1 111 6.15E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 Gene3D G3DSA:1.10.10.10 1 84 4.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.9E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16430 46b102625068f4247ac975648048a8c1 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 Gene3D G3DSA:3.40.50.720 3 264 9.9E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 SUPERFAMILY SSF51735 9 264 6.82E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.0E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 8.8E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20855 fc5647e34afe42be7688d7f452502172 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 262 6.5E-62 T 06-07-2017 CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 Pfam PF09339 IclR helix-turn-helix domain 7 54 3.9E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 Gene3D G3DSA:1.10.10.10 3 76 4.2E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 Gene3D G3DSA:3.30.450.40 77 243 4.6E-43 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 SUPERFAMILY SSF55781 76 243 8.5E-35 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 Pfam PF01614 Bacterial transcriptional regulator 127 242 1.2E-16 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 SMART SM00346 3 93 0.0017 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS25685 cc4095328f7018e0f99f17a4afa1d97a 246 SUPERFAMILY SSF46785 3 76 3.16E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Pfam PF00005 ABC transporter 19 161 3.9E-34 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 SUPERFAMILY SSF52540 4 242 3.5E-86 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Gene3D G3DSA:3.40.50.300 4 234 5.0E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 SMART SM00382 28 211 8.7E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Pfam PF08402 TOBE domain 275 341 1.6E-4 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Gene3D G3DSA:2.40.50.140 279 334 8.2E-10 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Gene3D G3DSA:2.40.50.100 239 278 1.9E-7 T 06-07-2017 CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 Gene3D G3DSA:2.40.50.100 335 349 1.9E-7 T 06-07-2017 CAL12_RS03245 10a0f13cf6ec5e937a039eeff5731f9c 353 SUPERFAMILY SSF50331 236 349 3.89E-26 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS13500 8a2576eeabadef292aba581e8c2e5b10 553 Pfam PF08774 VRR-NUC domain 436 548 4.4E-28 T 06-07-2017 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CAL12_RS13500 8a2576eeabadef292aba581e8c2e5b10 553 SMART SM00990 434 548 5.9E-39 T 06-07-2017 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 Pfam PF00202 Aminotransferase class-III 19 390 3.1E-103 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 392 41.268 T 06-07-2017 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 Gene3D G3DSA:3.90.1150.10 299 392 3.2E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 Gene3D G3DSA:3.90.1150.10 9 54 3.2E-26 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 Gene3D G3DSA:3.40.640.10 55 295 7.8E-82 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS00520 80b196949513a3c16f5e1161277ad566 396 SUPERFAMILY SSF53383 12 392 4.35E-113 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 Gene3D G3DSA:3.20.20.210 6 354 1.8E-142 T 06-07-2017 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 SUPERFAMILY SSF51726 6 354 1.05E-108 T 06-07-2017 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 352 47.673 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 349 5.7E-123 T 06-07-2017 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 351 3.0E-127 T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS25775 38a16004a536d4bf77070384246bc909 358 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 06-07-2017 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 122 7.0E-39 T 06-07-2017 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 Gene3D G3DSA:3.40.50.720 1 160 6.9E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 4.5E-91 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 34.075 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 06-07-2017 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 SUPERFAMILY SSF51735 1 123 1.52E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 SUPERFAMILY SSF51735 233 263 1.52E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 PIRSF PIRSF000161 1 263 1.2E-85 T 06-07-2017 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 SUPERFAMILY SSF55347 124 233 3.27E-36 T 06-07-2017 CAL12_RS06195 bfc6b90dfb50ee00d5c0f6590f12c861 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 1.5E-40 T 06-07-2017 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS12580 5e4d0934d2d2a34f8fda7111ec7d54e2 397 Pfam PF01070 FMN-dependent dehydrogenase 19 381 1.3E-133 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS12580 5e4d0934d2d2a34f8fda7111ec7d54e2 397 Gene3D G3DSA:3.20.20.70 10 381 1.1E-140 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS12580 5e4d0934d2d2a34f8fda7111ec7d54e2 397 SUPERFAMILY SSF51395 10 381 4.4E-102 T 06-07-2017 CAL12_RS12580 5e4d0934d2d2a34f8fda7111ec7d54e2 397 PIRSF PIRSF000138 5 386 3.0E-124 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS12580 5e4d0934d2d2a34f8fda7111ec7d54e2 397 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 279 285 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 SUPERFAMILY SSF55869 56 115 8.89E-23 T 06-07-2017 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 Gene3D G3DSA:3.90.15.10 120 250 2.1E-38 T 06-07-2017 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 117 318 1.1E-31 T 06-07-2017 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003918|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 SUPERFAMILY SSF56349 111 333 9.42E-67 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 264 278 1.6E-5 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 155 174 1.6E-5 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 199 215 1.6E-5 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 178 192 1.6E-5 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 314 325 1.6E-5 T 06-07-2017 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CAL12_RS14405 767e8e0087fa6acdf475c8e0ab0c4bf5 435 Gene3D G3DSA:1.20.120.380 265 334 5.8E-26 T 06-07-2017 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 SUPERFAMILY SSF55811 20 116 6.89E-8 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 SUPERFAMILY SSF55811 99 252 2.17E-39 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 113 144 4.5E-12 T 06-07-2017 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 Gene3D G3DSA:3.90.79.10 111 248 8.6E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 ProSitePatterns PS00893 Nudix box signature. 179 200 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS01650 238dc003830edf80dcd8097ecd1d8787 280 Pfam PF00293 NUDIX domain 150 250 7.0E-15 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS15165 f7032cf6f9b05758543950af1a2ee9c9 576 SUPERFAMILY SSF52016 378 563 3.06E-57 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS15165 f7032cf6f9b05758543950af1a2ee9c9 576 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS15165 f7032cf6f9b05758543950af1a2ee9c9 576 SUPERFAMILY SSF143975 3 376 1.83E-120 T 06-07-2017 CAL12_RS15165 f7032cf6f9b05758543950af1a2ee9c9 576 Pfam PF00920 Dehydratase family 41 557 4.3E-173 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS05475 0231e4e03a6fac2b911de695f8f8ad52 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 105 328 3.6E-14 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 9 458 7.0E-117 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Pfam PF02321 Outer membrane efflux protein 275 456 1.7E-25 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Pfam PF02321 Outer membrane efflux protein 59 249 6.3E-24 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 SUPERFAMILY SSF56954 2 461 1.44E-114 T 06-07-2017 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Gene3D G3DSA:1.20.1600.10 137 307 5.7E-103 T 06-07-2017 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Gene3D G3DSA:1.20.1600.10 345 459 5.7E-103 T 06-07-2017 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Gene3D G3DSA:1.20.1600.10 46 84 5.7E-103 T 06-07-2017 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Gene3D G3DSA:2.20.200.10 308 343 5.7E-15 T 06-07-2017 CAL12_RS22295 88ec17502af0868fabee5233b8f199e2 498 Gene3D G3DSA:2.20.200.10 94 136 5.7E-15 T 06-07-2017 CAL12_RS20840 b6c6eb89aef587c226e9ee13c7f0150e 474 SUPERFAMILY SSF89796 214 412 4.06E-59 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS20840 b6c6eb89aef587c226e9ee13c7f0150e 474 SUPERFAMILY SSF89796 37 203 1.22E-18 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS20840 b6c6eb89aef587c226e9ee13c7f0150e 474 Pfam PF02515 CoA-transferase family III 216 422 2.1E-50 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS20840 b6c6eb89aef587c226e9ee13c7f0150e 474 Gene3D G3DSA:3.40.50.10540 208 424 2.3E-65 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 Gene3D G3DSA:3.40.50.2300 2 134 1.5E-28 T 06-07-2017 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 Pfam PF01339 CheB methylesterase 179 357 1.2E-60 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 SUPERFAMILY SSF52738 174 359 1.44E-70 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 SUPERFAMILY SSF52172 1 133 5.69E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 PIRSF PIRSF000876 1 363 7.5E-133 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 Pfam PF00072 Response regulator receiver domain 6 108 4.1E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 Gene3D G3DSA:3.40.50.180 173 359 4.2E-81 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 362 39.934 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS23715 fc40b275c6629c622b26e45436609858 363 SMART SM00448 4 127 2.5E-20 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 Pfam PF00034 Cytochrome c 125 192 2.2E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 SUPERFAMILY SSF46626 116 195 6.82E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 SUPERFAMILY SSF46626 226 296 1.03E-16 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 Gene3D G3DSA:1.10.760.10 221 296 1.9E-24 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 Gene3D G3DSA:1.10.760.10 123 197 7.1E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS18570 d7e2f4778768811523d89ae90708f64f 299 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 226 292 2.3E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS12180 875ddd1baca0bbdea60bd455ff1640c2 395 Pfam PF02684 Lipid-A-disaccharide synthetase 6 371 1.3E-86 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAL12_RS12180 875ddd1baca0bbdea60bd455ff1640c2 395 Gene3D G3DSA:3.40.50.2000 157 296 5.1E-4 T 06-07-2017 CAL12_RS12180 875ddd1baca0bbdea60bd455ff1640c2 395 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 4 377 4.8E-92 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAL12_RS12180 875ddd1baca0bbdea60bd455ff1640c2 395 SUPERFAMILY SSF53756 4 365 3.64E-27 T 06-07-2017 CAL12_RS12180 875ddd1baca0bbdea60bd455ff1640c2 395 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 2 392 33.877 T 06-07-2017 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622 CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 181 2.7E-4 T 06-07-2017 CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 1.0E-56 T 06-07-2017 CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 Gene3D G3DSA:3.40.50.720 1 249 2.2E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 SUPERFAMILY SSF51735 1 248 5.4E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16915 dc58ee85186fefeeda22f83d8e32d97e 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.6E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 Pfam PF01614 Bacterial transcriptional regulator 191 306 7.4E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 SUPERFAMILY SSF55781 135 314 1.7E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 Gene3D G3DSA:1.10.10.10 64 137 2.8E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 SMART SM00346 69 160 7.5E-17 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 Pfam PF09339 IclR helix-turn-helix domain 72 122 1.0E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 SUPERFAMILY SSF46785 70 142 2.57E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11150 504f55fb700b2069db770a81e621d5d5 328 Gene3D G3DSA:3.30.450.40 138 313 3.5E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07120 6bbefd5255db645ae66344ad6e223293 117 Gene3D G3DSA:3.30.1330.40 10 116 2.0E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS07120 6bbefd5255db645ae66344ad6e223293 117 Pfam PF01042 Endoribonuclease L-PSP 10 115 6.0E-20 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS07120 6bbefd5255db645ae66344ad6e223293 117 SUPERFAMILY SSF55298 9 116 8.01E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:3.30.1480.10 1 128 8.6E-42 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF47794 359 418 1.08E-15 T 06-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF54814 202 280 6.21E-29 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Pfam PF08529 NusA N-terminal domain 4 127 2.6E-36 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:2.40.50.140 139 200 6.6E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:1.10.150.20 429 492 1.8E-24 T 06-07-2017 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:1.10.150.20 359 422 1.3E-21 T 06-07-2017 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF50249 136 201 1.09E-16 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF69705 1 129 3.53E-38 T 06-07-2017 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 442 488 9.2E-16 T 06-07-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 1.9E-18 T 06-07-2017 IPR010214 Transcription termination factor NusA, C-terminal duplication CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF47794 428 489 5.49E-15 T 06-07-2017 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Pfam PF14520 Helix-hairpin-helix domain 431 485 2.9E-9 T 06-07-2017 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 29.124 T 06-07-2017 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:3.30.300.20 201 279 1.6E-33 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 2.3E-123 T 06-07-2017 IPR010213 Transcription termination factor NusA GO:0003723 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SMART SM00316 136 202 6.5E-11 T 06-07-2017 IPR022967 RNA-binding domain, S1 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Pfam PF13184 NusA-like KH domain 232 299 7.4E-25 T 06-07-2017 IPR025249 KH domain, NusA-like GO:0003723 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 SUPERFAMILY SSF54814 281 344 2.42E-14 T 06-07-2017 IPR009019 K homology domain, prokaryotic type GO:0003723 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Pfam PF00575 S1 RNA binding domain 139 194 1.0E-7 T 06-07-2017 IPR003029 S1 domain GO:0003676 CAL12_RS18435 aad97d17634a0a747a4760de6e642b50 493 Gene3D G3DSA:3.30.300.20 280 348 1.4E-27 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS23345 897c388f9041b795066db94db0ae03f9 257 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23345 897c388f9041b795066db94db0ae03f9 257 Gene3D G3DSA:3.40.50.300 4 221 8.8E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23345 897c388f9041b795066db94db0ae03f9 257 SMART SM00382 34 227 1.1E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23345 897c388f9041b795066db94db0ae03f9 257 Pfam PF00005 ABC transporter 25 165 2.7E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23345 897c388f9041b795066db94db0ae03f9 257 SUPERFAMILY SSF52540 5 240 1.46E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10795 cbc39fc3f0bae2df702a32ca113f5299 487 Gene3D G3DSA:1.20.1250.20 273 461 4.3E-19 T 06-07-2017 CAL12_RS10795 cbc39fc3f0bae2df702a32ca113f5299 487 Gene3D G3DSA:1.20.1250.20 24 211 2.5E-30 T 06-07-2017 CAL12_RS10795 cbc39fc3f0bae2df702a32ca113f5299 487 SUPERFAMILY SSF103473 7 464 1.1E-71 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10795 cbc39fc3f0bae2df702a32ca113f5299 487 Pfam PF00083 Sugar (and other) transporter 58 448 1.1E-46 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 SUPERFAMILY SSF46785 2 83 9.54E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 Gene3D G3DSA:3.40.190.10 181 259 4.1E-12 T 06-07-2017 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 Pfam PF03466 LysR substrate binding domain 91 294 1.7E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 Gene3D G3DSA:1.10.10.10 5 89 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 Gene3D G3DSA:3.40.190.10 95 180 6.4E-28 T 06-07-2017 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.4E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19375 8b9ef6d1a61252436f3038b861a19249 319 SUPERFAMILY SSF53850 93 296 8.32E-35 T 06-07-2017 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 Gene3D G3DSA:3.90.190.20 293 434 2.3E-41 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 Gene3D G3DSA:3.40.1190.10 12 291 8.4E-96 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 SUPERFAMILY SSF53244 291 432 2.56E-31 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 SUPERFAMILY SSF53623 12 289 3.27E-89 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 PIRSF PIRSF001563 10 436 1.1E-104 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 Pfam PF08245 Mur ligase middle domain 53 267 1.5E-11 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS12075 c034e17727358eb2863cc89a65ea8fb1 436 TIGRFAM TIGR01499 folC: bifunctional protein FolC 32 432 3.4E-100 T 06-07-2017 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CAL12_RS02630 792d236df4b0b55a4f5fb5b5f7adfaba 126 Gene3D G3DSA:3.40.630.30 5 111 1.1E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02630 792d236df4b0b55a4f5fb5b5f7adfaba 126 SUPERFAMILY SSF55729 10 110 3.72E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02630 792d236df4b0b55a4f5fb5b5f7adfaba 126 Pfam PF13673 Acetyltransferase (GNAT) domain 15 110 2.0E-8 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS14460 cd3d77664b7e6e3edd40af3db486a7b9 341 SUPERFAMILY SSF53850 24 337 1.32E-60 T 06-07-2017 CAL12_RS14460 cd3d77664b7e6e3edd40af3db486a7b9 341 Gene3D G3DSA:3.40.190.10 128 280 2.4E-39 T 06-07-2017 CAL12_RS14460 cd3d77664b7e6e3edd40af3db486a7b9 341 Gene3D G3DSA:3.40.190.10 26 114 6.4E-6 T 06-07-2017 CAL12_RS14460 cd3d77664b7e6e3edd40af3db486a7b9 341 Pfam PF13343 Bacterial extracellular solute-binding protein 87 297 1.4E-24 T 06-07-2017 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 440 469 2.5E-50 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 363 390 2.5E-50 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.5E-50 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 286 315 2.5E-50 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 511 2.4E-51 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 Gene3D G3DSA:1.10.287.950 279 484 1.5E-53 T 06-07-2017 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 SUPERFAMILY SSF58104 232 513 5.75E-66 T 06-07-2017 CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 183 2.9E-14 T 06-07-2017 IPR024478 4HB MCP domain CAL12_RS13165 72624bc73470cfbe7fc34d19e15041b9 542 SMART SM00283 265 512 1.6E-75 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS20645 b48f4a820a314c1c6cd2d55a0e3b7d80 327 PIRSF PIRSF017082 3 326 8.0E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20645 b48f4a820a314c1c6cd2d55a0e3b7d80 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 3.4E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20645 b48f4a820a314c1c6cd2d55a0e3b7d80 327 SUPERFAMILY SSF53850 114 290 4.45E-16 T 06-07-2017 CAL12_RS22670 06d26efaa57b1b24b7a683c9bdfe076e 462 SUPERFAMILY SSF103088 340 455 9.42E-28 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22670 06d26efaa57b1b24b7a683c9bdfe076e 462 Gene3D G3DSA:3.30.1330.60 333 455 7.9E-29 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22670 06d26efaa57b1b24b7a683c9bdfe076e 462 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 67 275 2.3E-55 T 06-07-2017 IPR017732 Type IV / VI secretion system, DotU CAL12_RS22670 06d26efaa57b1b24b7a683c9bdfe076e 462 Pfam PF00691 OmpA family 352 449 1.1E-14 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS22670 06d26efaa57b1b24b7a683c9bdfe076e 462 Pfam PF09850 Type VI secretion system protein DotU 68 268 8.5E-56 T 06-07-2017 IPR017732 Type IV / VI secretion system, DotU CAL12_RS21695 05f5f3f3eeccab7f2d046cc01bb7c85a 290 SMART SM00382 34 192 1.1E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21695 05f5f3f3eeccab7f2d046cc01bb7c85a 290 Gene3D G3DSA:3.40.50.300 17 207 1.3E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21695 05f5f3f3eeccab7f2d046cc01bb7c85a 290 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 38 184 3.2E-14 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS21695 05f5f3f3eeccab7f2d046cc01bb7c85a 290 SUPERFAMILY SSF52540 16 244 1.83E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12445 ce237ee028a41e4f79bf0bad1f6b6d4f 483 Pfam PF05231 MASE1 71 354 4.1E-19 T 06-07-2017 IPR007895 MASE1 CAL12_RS12445 ce237ee028a41e4f79bf0bad1f6b6d4f 483 Gene3D G3DSA:3.30.450.20 358 479 1.2E-7 T 06-07-2017 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 06-07-2017 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 Pfam PF00444 Ribosomal protein L36 1 37 5.2E-18 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 SUPERFAMILY SSF57840 1 37 1.23E-16 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.97 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27515 50c7e417c300bc0ba24f48862f650f99 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.1E-21 T 06-07-2017 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 SUPERFAMILY SSF47616 79 204 1.34E-29 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 Pfam PF02798 Glutathione S-transferase, N-terminal domain 3 74 3.3E-15 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 SUPERFAMILY SSF52833 1 85 1.17E-23 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 Pfam PF13410 Glutathione S-transferase, C-terminal domain 143 191 7.3E-8 T 06-07-2017 CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 Gene3D G3DSA:1.20.1050.10 82 204 1.4E-29 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19310 2381149920def54868f89db7d484cb2f 208 Gene3D G3DSA:3.40.30.10 1 79 1.4E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.8E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 Gene3D G3DSA:3.40.190.10 93 179 1.2E-20 T 06-07-2017 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 Gene3D G3DSA:3.40.190.10 180 263 3.3E-21 T 06-07-2017 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 Gene3D G3DSA:1.10.10.10 3 87 2.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 SUPERFAMILY SSF53850 90 297 8.69E-45 T 06-07-2017 CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 Pfam PF03466 LysR substrate binding domain 89 295 1.3E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04190 f1d01794abefc8412b4ec5ab97811d86 307 SUPERFAMILY SSF46785 3 87 3.46E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07875 3c75eae928c664c8ccd6fca2f520b6f9 322 PIRSF PIRSF017082 1 322 7.3E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07875 3c75eae928c664c8ccd6fca2f520b6f9 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 317 4.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07875 3c75eae928c664c8ccd6fca2f520b6f9 322 Gene3D G3DSA:3.40.190.10 158 241 6.2E-4 T 06-07-2017 CAL12_RS07875 3c75eae928c664c8ccd6fca2f520b6f9 322 SUPERFAMILY SSF53850 100 284 1.77E-14 T 06-07-2017 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 Gene3D G3DSA:2.170.130.10 160 270 2.7E-30 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 Pfam PF00593 TonB dependent receptor 549 794 5.8E-34 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 SMART SM00965 49 100 2.6E-9 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 161 794 1.8E-82 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 Pfam PF07660 Secretin and TonB N terminus short domain 50 98 5.9E-7 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 Gene3D G3DSA:2.40.170.20 271 794 3.7E-104 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 SUPERFAMILY SSF56935 148 795 1.54E-112 T 06-07-2017 CAL12_RS14210 171a218582f21ea16133794307d94f37 796 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 269 1.9E-21 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.1E-39 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.1E-39 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.1E-39 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 SUPERFAMILY SSF74731 2 117 1.7E-49 T 06-07-2017 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 Pfam PF00453 Ribosomal protein L20 3 108 4.5E-49 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 3.0E-22 T 06-07-2017 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.4E-49 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 Gene3D G3DSA:1.10.1900.20 55 117 3.8E-30 T 06-07-2017 CAL12_RS09930 2a512613f6f721116c78324dc7388d12 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.332 T 06-07-2017 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 Pfam PF11741 AMIN domain 1 104 3.0E-23 T 06-07-2017 IPR021731 AMIN domain CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 Gene3D G3DSA:3.40.630.40 326 401 2.1E-58 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 Gene3D G3DSA:3.40.630.40 181 278 2.1E-58 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 SMART SM00646 243 398 1.1E-57 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 SUPERFAMILY SSF53187 325 401 2.42E-53 T 06-07-2017 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 SUPERFAMILY SSF53187 181 277 2.42E-53 T 06-07-2017 CAL12_RS06410 f332630aa7924a7e6d5e0f5620fdc29d 414 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 183 398 8.8E-48 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 SUPERFAMILY SSF53383 1 426 2.73E-116 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 Pfam PF00202 Aminotransferase class-III 5 423 2.4E-105 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 PIRSF PIRSF000521 12 426 9.4E-24 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 Gene3D G3DSA:3.90.1150.10 1 48 5.2E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 Gene3D G3DSA:3.90.1150.10 329 426 5.2E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 Gene3D G3DSA:3.40.640.10 49 327 1.4E-79 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02670 cd84b1037e9b7bd72b466922383c062d 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS23675 b2e881cb6e73d6494d00972eb23ee97b 59 Gene3D G3DSA:2.160.20.20 4 58 2.3E-6 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23675 b2e881cb6e73d6494d00972eb23ee97b 59 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 29 59 5.7E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23675 b2e881cb6e73d6494d00972eb23ee97b 59 SUPERFAMILY SSF51126 7 57 5.34E-6 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23675 b2e881cb6e73d6494d00972eb23ee97b 59 Pfam PF12951 Passenger-associated-transport-repeat 30 59 2.7E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS09830 59fda6cb813c008b18dc18412687b336 709 Pfam PF12805 FUSC-like inner membrane protein yccS 69 288 2.9E-30 T 06-07-2017 IPR032692 Integral membrane protein YccS, N-terminal CAL12_RS09830 59fda6cb813c008b18dc18412687b336 709 Pfam PF13515 Fusaric acid resistance protein-like 413 526 2.9E-15 T 06-07-2017 CAL12_RS09645 2c31859341e7b542982d85c867037517 658 Pfam PF00563 EAL domain 429 646 3.1E-23 T 06-07-2017 IPR001633 EAL domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 Gene3D G3DSA:3.20.20.450 425 647 1.5E-24 T 06-07-2017 IPR001633 EAL domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 Gene3D G3DSA:3.30.70.270 249 406 2.2E-17 T 06-07-2017 CAL12_RS09645 2c31859341e7b542982d85c867037517 658 SMART SM00052 422 657 7.2E-10 T 06-07-2017 IPR001633 EAL domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 SUPERFAMILY SSF141868 428 647 1.83E-27 T 06-07-2017 IPR001633 EAL domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 Pfam PF16448 LapD/MoxY periplasmic domain 37 155 1.1E-15 T 06-07-2017 IPR032244 LapD/MoxY, periplasmic domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 Pfam PF00990 Diguanylate cyclase, GGDEF domain 248 405 2.1E-14 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 SMART SM00267 236 412 4.3E-7 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS09645 2c31859341e7b542982d85c867037517 658 SUPERFAMILY SSF55073 253 407 5.26E-14 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS22130 7bed030e15d098ce0c40c9d47575e5d2 120 Gene3D G3DSA:1.25.40.10 13 110 2.0E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22130 7bed030e15d098ce0c40c9d47575e5d2 120 SUPERFAMILY SSF48452 7 114 4.88E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS25035 6a5cd5a4e753ab289c315c3fa484f126 238 SMART SM00382 26 215 4.1E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25035 6a5cd5a4e753ab289c315c3fa484f126 238 Pfam PF00005 ABC transporter 19 166 3.4E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25035 6a5cd5a4e753ab289c315c3fa484f126 238 SUPERFAMILY SSF52540 2 235 2.09E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25035 6a5cd5a4e753ab289c315c3fa484f126 238 Gene3D G3DSA:3.40.50.300 2 230 1.3E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25035 6a5cd5a4e753ab289c315c3fa484f126 238 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS26175 d758cd2de65833e376835de99b3b7dcb 263 Gene3D G3DSA:3.40.50.720 3 247 4.7E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26175 d758cd2de65833e376835de99b3b7dcb 263 SUPERFAMILY SSF69572 2 246 4.97E-85 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAL12_RS26175 d758cd2de65833e376835de99b3b7dcb 263 Pfam PF00899 ThiF family 9 243 2.8E-64 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 SUPERFAMILY SSF46785 3 86 2.46E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 Gene3D G3DSA:3.40.190.10 179 265 2.1E-19 T 06-07-2017 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.9E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 Gene3D G3DSA:1.10.10.10 5 90 1.7E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 2.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 SUPERFAMILY SSF53850 93 300 8.14E-36 T 06-07-2017 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 Gene3D G3DSA:3.40.190.10 96 178 9.1E-16 T 06-07-2017 CAL12_RS15055 70e726bea62d3786874d8b5e63524dc6 306 Pfam PF03466 LysR substrate binding domain 92 294 3.4E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 Gene3D G3DSA:3.40.1690.10 218 354 3.0E-64 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 354 3.6E-125 T 06-07-2017 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 3.9E-127 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 3.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 3.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 3.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 3.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 3.8E-40 T 06-07-2017 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CAL12_RS11860 b2266597457999c3fc2eeea9bd185286 390 SUPERFAMILY SSF160544 245 351 1.31E-42 T 06-07-2017 IPR029025 Type III secretion system substrate exporter, C-terminal CAL12_RS09110 cff5a0d66476e02210b7d54499d815c3 292 Pfam PF03476 MOSC N-terminal beta barrel domain 5 117 2.9E-27 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel CAL12_RS09110 cff5a0d66476e02210b7d54499d815c3 292 SUPERFAMILY SSF141673 5 131 1.1E-34 T 06-07-2017 CAL12_RS09110 cff5a0d66476e02210b7d54499d815c3 292 Pfam PF03473 MOSC domain 160 286 1.9E-23 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CAL12_RS09110 cff5a0d66476e02210b7d54499d815c3 292 SUPERFAMILY SSF50800 2 50 6.38E-18 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAL12_RS09110 cff5a0d66476e02210b7d54499d815c3 292 SUPERFAMILY SSF50800 167 289 6.38E-18 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 SMART SM00382 40 239 5.7E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 Pfam PF00005 ABC transporter 32 189 3.5E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.5E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 Gene3D G3DSA:3.40.50.300 10 262 1.7E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 SUPERFAMILY SSF52540 40 314 4.38E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27915 39aed76ab4580a7d495387c03ca79b44 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 323 2.4E-27 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 SUPERFAMILY SSF100920 385 541 1.57E-60 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.30.420.40 119 197 6.3E-64 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.30.420.40 4 52 6.3E-64 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 637 36.796 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 3 16 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 366 386 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 470 486 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 54 62 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 138 158 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 389 408 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 335 351 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 31 43 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 PRINTS PR00301 70kDa heat shock protein signature 199 209 8.2E-81 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.1E-289 T 06-07-2017 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 SUPERFAMILY SSF53067 4 183 2.72E-65 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Pfam PF00012 Hsp70 protein 4 604 2.1E-263 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:1.20.1270.10 533 604 1.1E-26 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.90.640.10 231 316 3.4E-31 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 SUPERFAMILY SSF53067 188 383 1.85E-67 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:2.60.34.10 391 532 6.8E-71 T 06-07-2017 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.30.420.40 320 362 2.5E-32 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.30.420.40 198 230 2.5E-32 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 Gene3D G3DSA:3.30.30.30 53 108 1.1E-25 T 06-07-2017 CAL12_RS06240 7c8b9365c4fe2706687530d505d39f48 641 SUPERFAMILY SSF100934 508 605 1.51E-19 T 06-07-2017 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 201 840 8.0E-88 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 Gene3D G3DSA:2.40.170.20 316 840 2.7E-111 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 Pfam PF07715 TonB-dependent Receptor Plug Domain 200 291 1.8E-12 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 Pfam PF07660 Secretin and TonB N terminus short domain 110 156 3.2E-10 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 Gene3D G3DSA:2.170.130.10 157 309 3.4E-28 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 SMART SM00965 106 157 1.5E-13 T 06-07-2017 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 SUPERFAMILY SSF56935 157 840 2.04E-112 T 06-07-2017 CAL12_RS02015 23887e9f3008dac4d44b780a04137af7 841 Pfam PF00593 TonB dependent receptor 614 839 2.6E-29 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 SUPERFAMILY SSF50249 1 66 1.82E-23 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 PRINTS PR00050 Cold shock protein signature 4 19 7.0E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 PRINTS PR00050 Cold shock protein signature 40 58 7.0E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 PRINTS PR00050 Cold shock protein signature 25 34 7.0E-13 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 PIRSF PIRSF002599 1 67 2.3E-21 T 06-07-2017 IPR012156 Cold shock, CspA GO:0003676 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 SMART SM00357 3 67 6.6E-25 T 06-07-2017 IPR011129 Cold shock protein GO:0003676 CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 Gene3D G3DSA:2.40.50.140 1 66 3.3E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 06-07-2017 IPR019844 Cold-shock conserved site CAL12_RS21910 f00fda609162e52aeade6b93d9e30470 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.7E-27 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 7.7E-41 T 06-07-2017 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 SUPERFAMILY SSF51905 7 173 1.44E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 SUPERFAMILY SSF51905 257 338 1.44E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 Gene3D G3DSA:3.50.50.60 258 337 1.5E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 Gene3D G3DSA:3.50.50.60 7 178 1.5E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12560 929f36871860be3eeb13bccf56782b70 523 Pfam PF01494 FAD binding domain 5 333 3.2E-68 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS03675 b3c99351063ec75f5261444b75e6c077 268 Gene3D G3DSA:1.10.3720.10 61 252 3.6E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03675 b3c99351063ec75f5261444b75e6c077 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 252 2.5E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03675 b3c99351063ec75f5261444b75e6c077 268 SUPERFAMILY SSF161098 63 243 2.49E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Hamap MF_00006 Argininosuccinate lyase [argH]. 17 468 43.051 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Gene3D G3DSA:1.10.275.10 17 121 2.2E-38 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Gene3D G3DSA:1.20.200.10 122 388 3.3E-111 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Gene3D G3DSA:1.10.40.30 389 446 7.3E-32 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 SUPERFAMILY SSF48557 19 464 2.2E-150 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Pfam PF00206 Lyase 22 315 1.8E-74 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 TIGRFAM TIGR00838 argH: argininosuccinate lyase 19 465 5.9E-185 T 06-07-2017 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 246 270 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 325 344 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 116 138 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 157 177 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00145 Argininosuccinate lyase family signature 208 224 4.8E-68 T 06-07-2017 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 Pfam PF14698 Argininosuccinate lyase C-terminal 378 446 3.0E-25 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 1.9E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 1.9E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 1.9E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS15950 65844bbde783dcfe840c29f39bde9fb6 472 PRINTS PR00149 Fumarate lyase superfamily signature 246 273 1.9E-30 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS03380 b57dbdd2fdfaf09da6232ec3af13fafb 161 Pfam PF04115 Ureidoglycolate lyase 57 124 2.7E-13 T 06-07-2017 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CAL12_RS03380 b57dbdd2fdfaf09da6232ec3af13fafb 161 SUPERFAMILY SSF51182 17 147 3.87E-18 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03380 b57dbdd2fdfaf09da6232ec3af13fafb 161 Gene3D G3DSA:2.60.120.480 45 149 7.7E-18 T 06-07-2017 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 CAL12_RS01340 a124ac6d5cd92ed336185fc0ddaac1ca 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 213 2.1E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01340 a124ac6d5cd92ed336185fc0ddaac1ca 217 Gene3D G3DSA:1.10.3720.10 12 213 2.5E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01340 a124ac6d5cd92ed336185fc0ddaac1ca 217 SUPERFAMILY SSF161098 13 206 8.5E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01340 a124ac6d5cd92ed336185fc0ddaac1ca 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 2.0E-28 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS21590 dfcad80858a533cab899e0ca5d3a03aa 202 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 196 2.4E-71 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAL12_RS21590 dfcad80858a533cab899e0ca5d3a03aa 202 PIRSF PIRSF001296 11 202 4.8E-74 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAL12_RS21590 dfcad80858a533cab899e0ca5d3a03aa 202 Pfam PF02669 K+-transporting ATPase, c chain 15 196 1.3E-73 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAL12_RS21590 dfcad80858a533cab899e0ca5d3a03aa 202 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 11 198 34.005 T 06-07-2017 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 Pfam PF07729 FCD domain 77 196 1.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 Gene3D G3DSA:1.10.10.10 2 68 2.8E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 SMART SM00895 77 197 5.2E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 4.0E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 4.0E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 Gene3D G3DSA:1.20.120.530 71 208 2.1E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 SUPERFAMILY SSF46785 4 71 7.13E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 SUPERFAMILY SSF48008 73 204 7.59E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 SMART SM00345 9 67 1.8E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS06850 bd8cafc490a5b99a2fa21f3d7fea7b53 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 67 9.6E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS26605 fb89ee2ebcd8eb9f21c6e14f1fae022d 286 SUPERFAMILY SSF54197 44 284 9.36E-50 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS26605 fb89ee2ebcd8eb9f21c6e14f1fae022d 286 Gene3D G3DSA:3.30.428.30 41 284 3.7E-55 T 06-07-2017 CAL12_RS26605 fb89ee2ebcd8eb9f21c6e14f1fae022d 286 Pfam PF02611 CDP-diacylglycerol pyrophosphatase 45 284 3.6E-55 T 06-07-2017 IPR003763 CDP-diacylglycerol pyrophosphatase GO:0008654|GO:0008715|GO:0016020 KEGG: 00564+3.6.1.26 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 SUPERFAMILY SSF55021 3 77 1.97E-10 T 06-07-2017 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 Gene3D G3DSA:3.30.70.260 1 79 2.9E-15 T 06-07-2017 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 SUPERFAMILY SSF53328 87 281 3.4E-60 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 281 2.6E-98 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 Pfam PF00551 Formyl transferase 87 263 1.6E-37 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 87 109 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 109 136 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 255 280 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 233 255 1.6E-42 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 Gene3D G3DSA:3.40.50.170 87 280 3.9E-55 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 PIRSF PIRSF036480 1 281 4.5E-105 T 06-07-2017 CAL12_RS06110 c93728a2531d65474d094375fa5d55e6 281 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 281 44.84 T 06-07-2017 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 SUPERFAMILY SSF55174 3 207 4.19E-66 T 06-07-2017 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 2.3E-31 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 Gene3D G3DSA:1.10.1050.10 1 102 3.1E-43 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 4.4E-77 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 SMART SM01390 3 96 5.8E-49 T 06-07-2017 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 06-07-2017 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.417 T 06-07-2017 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 SMART SM00363 97 161 4.2E-16 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 Gene3D G3DSA:3.10.290.10 103 191 1.0E-30 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS27500 33fbe87acb6d2202d52e31f7b288b324 207 Pfam PF01479 S4 domain 98 144 5.9E-17 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 SUPERFAMILY SSF53850 89 299 2.53E-39 T 06-07-2017 CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 Pfam PF03466 LysR substrate binding domain 88 295 3.7E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 Gene3D G3DSA:3.40.190.10 92 174 1.4E-22 T 06-07-2017 CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 Gene3D G3DSA:1.10.10.10 3 86 2.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 Gene3D G3DSA:3.40.190.10 175 263 3.6E-17 T 06-07-2017 CAL12_RS03760 6d02e83c62cfef8b987e5d441e73e7cf 305 SUPERFAMILY SSF46785 6 86 9.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 SMART SM00345 25 84 2.6E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 Gene3D G3DSA:3.40.640.10 157 376 3.4E-56 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 Gene3D G3DSA:1.10.10.10 13 85 3.1E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 SUPERFAMILY SSF53383 79 485 5.84E-84 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 Pfam PF00155 Aminotransferase class I and II 158 427 8.9E-26 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 2.6E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20025 62601890ad80f048d79f8837118e8d4f 488 SUPERFAMILY SSF46785 17 94 2.6E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 Gene3D G3DSA:3.40.190.10 82 189 1.6E-13 T 06-07-2017 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 SUPERFAMILY SSF53850 91 262 6.7E-21 T 06-07-2017 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 SUPERFAMILY SSF46785 5 112 1.25E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 Pfam PF03466 LysR substrate binding domain 90 262 2.7E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 Gene3D G3DSA:3.40.190.10 190 237 3.4E-7 T 06-07-2017 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06670 1d3c97a46605a3777ca4294473a3b4a2 285 Gene3D G3DSA:1.10.10.10 5 81 2.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25785 f02f0fe30d25b3683e46fd24a833d774 389 Pfam PF03929 PepSY-associated TM region 10 365 7.0E-54 T 06-07-2017 IPR005625 PepSY-associated TM protein CAL12_RS11815 11d59bca32cbd05a7f22fcb4c87be6f5 327 SUPERFAMILY SSF103088 159 271 9.68E-20 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS11815 11d59bca32cbd05a7f22fcb4c87be6f5 327 Pfam PF00691 OmpA family 167 250 1.1E-11 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS11815 11d59bca32cbd05a7f22fcb4c87be6f5 327 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 13 65 8.0E-20 T 06-07-2017 IPR025713 Motility protein B, N-terminal domain CAL12_RS11815 11d59bca32cbd05a7f22fcb4c87be6f5 327 Gene3D G3DSA:3.30.1330.60 160 271 3.9E-18 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 281 288 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 Gene3D G3DSA:3.40.309.10 296 483 6.0E-68 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 310 321 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 Pfam PF00171 Aldehyde dehydrogenase family 49 508 1.6E-170 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 SUPERFAMILY SSF53720 33 510 8.9E-169 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS02390 60ef884fb2704e555b91b890e89471df 512 Gene3D G3DSA:3.40.605.10 36 295 4.9E-96 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS13355 035ad7288284c9621219530fb470aa87 167 Pfam PF13185 GAF domain 24 155 1.6E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS13355 035ad7288284c9621219530fb470aa87 167 Gene3D G3DSA:3.30.450.40 8 136 3.3E-7 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13355 035ad7288284c9621219530fb470aa87 167 SUPERFAMILY SSF55781 23 163 1.65E-10 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS02170 ce7e22893c444e3369a9cd6f627c7969 332 Gene3D G3DSA:3.40.50.1820 6 316 3.5E-86 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02170 ce7e22893c444e3369a9cd6f627c7969 332 Pfam PF12697 Alpha/beta hydrolase family 71 260 2.8E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS02170 ce7e22893c444e3369a9cd6f627c7969 332 SUPERFAMILY SSF53474 66 316 5.65E-28 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 Pfam PF00072 Response regulator receiver domain 8 120 1.0E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 5.6E-21 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 Gene3D G3DSA:1.10.10.10 124 212 4.0E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 SMART SM00421 149 206 1.8E-20 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 Gene3D G3DSA:3.40.50.2300 5 123 1.6E-36 T 06-07-2017 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 SUPERFAMILY SSF52172 5 135 2.56E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 SUPERFAMILY SSF46894 146 212 1.02E-20 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.3E-11 T 06-07-2017 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CAL12_RS14360 25ebbfbf2594ac52e6feb98b517e6371 213 SMART SM00448 6 119 9.9E-32 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 256 2.6E-75 T 06-07-2017 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 254 6.3E-69 T 06-07-2017 CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 06-07-2017 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 Gene3D G3DSA:3.60.10.10 1 257 9.9E-92 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 249 1.3E-21 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS25330 3abe031ffeeab2bdc7e9d0eaa07c8fa9 260 SUPERFAMILY SSF56219 2 257 9.95E-74 T 06-07-2017 IPR005135 Endonuclease/exonuclease/phosphatase CAL12_RS22395 cec4f3422d24073e0c9a21f63870ed25 273 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 253 23.551 T 06-07-2017 IPR026579 Cell division protein FtsQ GO:0090529 CAL12_RS22395 cec4f3422d24073e0c9a21f63870ed25 273 Pfam PF08478 POTRA domain, FtsQ-type 68 110 3.8E-11 T 06-07-2017 IPR013685 Polypeptide-transport-associated, FtsQ-type CAL12_RS22395 cec4f3422d24073e0c9a21f63870ed25 273 Pfam PF03799 Cell division protein FtsQ 114 245 3.2E-23 T 06-07-2017 IPR005548 Cell division protein FtsQ/DivIB CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 Gene3D G3DSA:3.40.190.10 179 262 1.9E-13 T 06-07-2017 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.7E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 Gene3D G3DSA:1.10.10.10 1 85 1.9E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 SUPERFAMILY SSF53850 89 297 1.33E-34 T 06-07-2017 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 Gene3D G3DSA:3.40.190.10 89 178 9.3E-20 T 06-07-2017 CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 SUPERFAMILY SSF46785 1 110 3.31E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20705 eac2ccfaa39dbfc5938c702c106962fc 322 Pfam PF03466 LysR substrate binding domain 87 288 9.6E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 SMART SM00091 8 74 4.3E-4 T 06-07-2017 IPR000014 PAS domain CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 Gene3D G3DSA:1.10.287.950 292 490 2.5E-50 T 06-07-2017 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 446 475 2.2E-42 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 369 396 2.2E-42 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 292 321 2.2E-42 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 2.2E-42 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 SMART SM00304 218 270 1.2E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 Gene3D G3DSA:3.30.450.20 21 114 1.1E-25 T 06-07-2017 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 SUPERFAMILY SSF58104 238 519 9.02E-61 T 06-07-2017 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 Pfam PF08447 PAS fold 31 114 1.7E-18 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 SUPERFAMILY SSF55785 21 115 9.77E-28 T 06-07-2017 IPR000014 PAS domain CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 SMART SM00283 271 518 1.8E-70 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 24 120 5.9E-15 T 06-07-2017 IPR000014 PAS domain CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 Pfam PF00672 HAMP domain 206 262 9.9E-10 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11170 2cd4c9eb9961f66a8ada831a5270fa4b 545 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 515 5.7E-48 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS13690 642100bd4c5ace6d21d413fbf11e82cb 442 SUPERFAMILY SSF53649 3 436 1.74E-111 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS13690 642100bd4c5ace6d21d413fbf11e82cb 442 Pfam PF00884 Sulfatase 4 326 2.2E-66 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS13690 642100bd4c5ace6d21d413fbf11e82cb 442 Pfam PF14707 C-terminal region of aryl-sulfatase 352 435 1.2E-8 T 06-07-2017 CAL12_RS13690 642100bd4c5ace6d21d413fbf11e82cb 442 Gene3D G3DSA:3.40.720.10 3 367 5.4E-99 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS13690 642100bd4c5ace6d21d413fbf11e82cb 442 Gene3D G3DSA:3.30.1120.10 368 435 7.8E-8 T 06-07-2017 CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 SUPERFAMILY SSF46785 3 112 3.22E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 Gene3D G3DSA:3.40.190.10 93 179 3.3E-19 T 06-07-2017 CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 Gene3D G3DSA:3.40.190.10 180 265 7.7E-14 T 06-07-2017 CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 Pfam PF03466 LysR substrate binding domain 89 297 4.5E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 SUPERFAMILY SSF53850 83 297 1.5E-34 T 06-07-2017 CAL12_RS16420 fc56a637da10db8af7892d05caba53f9 304 Gene3D G3DSA:1.10.10.10 3 88 8.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 Gene3D G3DSA:2.40.50.100 157 190 2.3E-17 T 06-07-2017 CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 Gene3D G3DSA:2.40.50.100 51 84 2.3E-17 T 06-07-2017 CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 236 5.2E-31 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 SUPERFAMILY SSF111369 44 209 2.35E-22 T 06-07-2017 CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 Pfam PF13533 Biotin-lipoyl like 51 98 6.5E-19 T 06-07-2017 CAL12_RS16195 fbb383aebe2d3f65117a0fe174822fdd 300 Pfam PF13437 HlyD family secretion protein 160 240 3.5E-8 T 06-07-2017 CAL12_RS10475 a7514f7df13a520d4c26c7da302cda8d 307 SUPERFAMILY SSF88713 7 306 4.45E-66 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS10475 a7514f7df13a520d4c26c7da302cda8d 307 Gene3D G3DSA:3.20.20.370 7 306 4.3E-83 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS10475 a7514f7df13a520d4c26c7da302cda8d 307 Pfam PF01522 Polysaccharide deacetylase 76 183 2.7E-19 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 Gene3D G3DSA:3.40.50.1980 214 335 1.2E-42 T 06-07-2017 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 Pfam PF01297 Zinc-uptake complex component A periplasmic 48 331 1.7E-81 T 06-07-2017 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 SUPERFAMILY SSF53807 41 335 3.29E-85 T 06-07-2017 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00690 Adhesin family signature 89 106 4.9E-19 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00690 Adhesin family signature 76 89 4.9E-19 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00690 Adhesin family signature 274 292 4.9E-19 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00690 Adhesin family signature 300 319 4.9E-19 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00690 Adhesin family signature 45 63 4.9E-19 T 06-07-2017 IPR006128 Adhesion lipoprotein GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 45 66 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 70 88 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 89 108 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 313 331 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 270 287 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 PRINTS PR00691 Adhesin B signature 292 310 3.3E-19 T 06-07-2017 IPR006129 Adhesin B GO:0007155 CAL12_RS26710 3df033c6225362aeeced6247f24cf350 336 Gene3D G3DSA:3.40.50.1980 40 213 1.9E-53 T 06-07-2017 CAL12_RS27925 e06840594035f29f17e69c7c65da8167 286 Gene3D G3DSA:3.40.630.40 6 283 6.4E-92 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS27925 e06840594035f29f17e69c7c65da8167 286 Pfam PF05013 N-formylglutamate amidohydrolase 22 253 2.9E-62 T 06-07-2017 IPR007709 N-formylglutamate amidohydrolase CAL12_RS27925 e06840594035f29f17e69c7c65da8167 286 SUPERFAMILY SSF53187 10 283 2.13E-81 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 SUPERFAMILY SSF51905 288 382 2.59E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 SUPERFAMILY SSF51905 14 195 2.59E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 Pfam PF01494 FAD binding domain 12 367 1.5E-78 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 Gene3D G3DSA:3.50.50.60 299 338 6.4E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 Gene3D G3DSA:3.50.50.60 10 185 6.4E-47 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 Gene3D G3DSA:3.30.9.10 186 298 2.5E-12 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 Gene3D G3DSA:3.30.9.10 349 391 2.5E-12 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 2.4E-41 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 2.4E-41 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 2.4E-41 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 174 189 2.4E-41 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 2.4E-41 T 06-07-2017 CAL12_RS20810 5075d157bb441f7110f1ff28c0fd83aa 550 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 2.4E-41 T 06-07-2017 CAL12_RS06385 35417cce3f107fbf9c52c55b27dccca5 233 Gene3D G3DSA:1.10.8.60 161 226 1.1E-25 T 06-07-2017 CAL12_RS06385 35417cce3f107fbf9c52c55b27dccca5 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 4 226 3.3E-66 T 06-07-2017 IPR017788 DnaA regulatory inactivator Hda GO:0032297 CAL12_RS06385 35417cce3f107fbf9c52c55b27dccca5 233 Gene3D G3DSA:3.40.50.300 2 158 3.7E-25 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06385 35417cce3f107fbf9c52c55b27dccca5 233 Pfam PF00308 Bacterial dnaA protein 92 206 3.1E-7 T 06-07-2017 IPR013317 Chromosomal replication initiator protein DnaA CAL12_RS06385 35417cce3f107fbf9c52c55b27dccca5 233 SUPERFAMILY SSF52540 34 206 1.26E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 SUPERFAMILY SSF46785 3 88 3.18E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 Gene3D G3DSA:1.10.10.10 2 88 5.0E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.6E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 Pfam PF03466 LysR substrate binding domain 89 292 7.3E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.6E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 SUPERFAMILY SSF53850 91 295 3.26E-35 T 06-07-2017 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 Gene3D G3DSA:3.40.190.10 90 176 7.8E-20 T 06-07-2017 CAL12_RS15270 63101ff6d12a202b1bdcb6ac5b37965c 299 Gene3D G3DSA:3.40.190.10 177 259 5.5E-17 T 06-07-2017 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 Pfam PF01544 CorA-like Mg2+ transporter protein 64 351 9.2E-53 T 06-07-2017 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 Gene3D G3DSA:1.20.58.340 165 276 9.4E-29 T 06-07-2017 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 SUPERFAMILY SSF143865 26 282 3.66E-51 T 06-07-2017 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 SUPERFAMILY SSF144083 290 352 2.48E-19 T 06-07-2017 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 Gene3D G3DSA:1.20.58.340 284 355 6.0E-25 T 06-07-2017 CAL12_RS08090 b5c31fc7c5921c84d33f7f14badbd797 355 Gene3D G3DSA:3.30.460.20 34 164 1.1E-18 T 06-07-2017 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 SUPERFAMILY SSF88697 286 377 2.76E-26 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 SMART SM00359 287 370 1.6E-17 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 Pfam PF00696 Amino acid kinase family 15 244 1.1E-43 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PIRSF PIRSF000729 10 378 1.6E-126 T 06-07-2017 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 Pfam PF01472 PUA domain 287 360 6.5E-25 T 06-07-2017 IPR002478 PUA domain GO:0003723 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 TIGRFAM TIGR01027 proB: glutamate 5-kinase 16 376 2.4E-127 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 Gene3D G3DSA:3.40.1160.10 12 263 1.7E-56 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 06-07-2017 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 3.4E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 3.4E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 3.4E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 3.4E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 3.4E-50 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 268 35.685 T 06-07-2017 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 SUPERFAMILY SSF53633 16 264 2.36E-68 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS01770 6c37e2ecb2c800e18f17aacda477da08 378 Gene3D G3DSA:2.30.130.10 285 376 4.1E-29 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS23125 04cdf3c3dc3b0f11295ace00527274d1 325 Pfam PF09084 NMT1/THI5 like 43 245 6.7E-23 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS23125 04cdf3c3dc3b0f11295ace00527274d1 325 Gene3D G3DSA:3.40.190.10 113 208 5.1E-7 T 06-07-2017 CAL12_RS23125 04cdf3c3dc3b0f11295ace00527274d1 325 SUPERFAMILY SSF53850 29 258 8.26E-33 T 06-07-2017 CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 Pfam PF01614 Bacterial transcriptional regulator 147 251 9.0E-6 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 Gene3D G3DSA:3.30.450.40 99 270 4.3E-27 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 SUPERFAMILY SSF46785 25 94 1.23E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 Gene3D G3DSA:1.10.10.10 21 93 1.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 SUPERFAMILY SSF55781 82 270 3.01E-29 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 SMART SM00346 24 114 7.3E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS13645 9d4fd89d7cd3cfc19f02e7eb2ef138e3 273 Pfam PF09339 IclR helix-turn-helix domain 27 76 1.4E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Gene3D G3DSA:3.40.50.970 10 182 4.1E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 331 3.7E-26 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 174 8.0E-53 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 SUPERFAMILY SSF52518 368 547 1.73E-62 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 537 6.0E-45 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 SUPERFAMILY SSF52467 159 360 5.61E-39 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 SUPERFAMILY SSF52518 10 183 3.08E-51 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Gene3D G3DSA:3.40.50.970 365 549 2.9E-64 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS05345 94274fdac19887ff7d0ce815083764a0 562 Gene3D G3DSA:3.40.50.1220 186 338 6.6E-36 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS12480 bf3a544b23b673c4bf12aaace7e016b7 258 Pfam PF00005 ABC transporter 29 182 1.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12480 bf3a544b23b673c4bf12aaace7e016b7 258 SMART SM00382 37 230 3.9E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12480 bf3a544b23b673c4bf12aaace7e016b7 258 Gene3D G3DSA:3.40.50.300 10 250 2.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12480 bf3a544b23b673c4bf12aaace7e016b7 258 SUPERFAMILY SSF52540 12 253 6.21E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12480 bf3a544b23b673c4bf12aaace7e016b7 258 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 234 252 3.4E-5 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 Pfam PF09339 IclR helix-turn-helix domain 28 72 5.7E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 SMART SM00346 25 113 1.0E-9 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 SUPERFAMILY SSF55781 97 270 1.44E-33 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 SUPERFAMILY SSF46785 26 92 4.49E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 Gene3D G3DSA:1.10.10.10 23 91 3.4E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 Gene3D G3DSA:3.30.450.40 97 271 1.8E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS16215 d9d93a865a21b23b8a323dec6a6b5141 276 Pfam PF01614 Bacterial transcriptional regulator 143 266 3.9E-12 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 Gene3D G3DSA:3.10.20.70 4 106 6.7E-37 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 SUPERFAMILY SSF54368 4 100 8.37E-34 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 SUPERFAMILY SSF55931 104 469 1.08E-140 T 06-07-2017 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 06-07-2017 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 SMART SM01230 103 380 1.2E-151 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 06-07-2017 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 06-07-2017 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 469 2.5E-195 T 06-07-2017 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 Gene3D G3DSA:3.30.590.10 107 456 8.8E-140 T 06-07-2017 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 Pfam PF00120 Glutamine synthetase, catalytic domain 104 467 1.1E-138 T 06-07-2017 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS15320 ecdf26b7ca7fc571c97f69f5f46c400e 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 8.3E-30 T 06-07-2017 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CAL12_RS20285 37b8755feefd0369b0346d829cd326c1 130 Gene3D G3DSA:3.40.1050.10 26 72 2.0E-4 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS13540 e85a59cafb4c370bc47f83cf1932eaab 252 Gene3D G3DSA:3.40.50.10320 45 248 1.7E-34 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAL12_RS13540 e85a59cafb4c370bc47f83cf1932eaab 252 SUPERFAMILY SSF102588 45 250 1.02E-39 T 06-07-2017 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CAL12_RS13540 e85a59cafb4c370bc47f83cf1932eaab 252 Pfam PF02585 GlcNAc-PI de-N-acetylase 45 168 1.3E-20 T 06-07-2017 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CAL12_RS13845 e7b340046ff715fff824a84020161f3b 262 SUPERFAMILY SSF56524 59 261 5.1E-62 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS13845 e7b340046ff715fff824a84020161f3b 262 Gene3D G3DSA:3.90.420.10 100 260 1.1E-53 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS13845 e7b340046ff715fff824a84020161f3b 262 Pfam PF00174 Oxidoreductase molybdopterin binding domain 108 251 6.7E-32 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 Gene3D G3DSA:3.40.50.720 3 242 1.9E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 5.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 5.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 5.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 5.2E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 Pfam PF00106 short chain dehydrogenase 8 205 4.5E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 SUPERFAMILY SSF51735 3 242 2.1E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS20790 77429022b3cf2c4909e91b2a3dc64d01 282 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 3.4E-6 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17080 350dbde6840087d5a0768f67af92cbda 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 3.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS17080 350dbde6840087d5a0768f67af92cbda 307 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 3.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS17080 350dbde6840087d5a0768f67af92cbda 307 Gene3D G3DSA:3.40.50.1820 17 306 2.9E-72 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS17080 350dbde6840087d5a0768f67af92cbda 307 SUPERFAMILY SSF53474 18 293 3.03E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS17080 350dbde6840087d5a0768f67af92cbda 307 Pfam PF12697 Alpha/beta hydrolase family 34 292 8.6E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 SUPERFAMILY SSF55031 218 330 2.69E-29 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 Pfam PF07687 Peptidase dimerisation domain 218 314 5.2E-5 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 PIRSF PIRSF001235 11 415 2.4E-132 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 Gene3D G3DSA:3.30.70.360 231 330 8.1E-37 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 Gene3D G3DSA:3.40.630.10 10 230 1.9E-116 T 06-07-2017 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 Gene3D G3DSA:3.40.630.10 353 413 1.9E-116 T 06-07-2017 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 16 408 4.3E-128 T 06-07-2017 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 SUPERFAMILY SSF53187 7 228 4.29E-94 T 06-07-2017 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 SUPERFAMILY SSF53187 338 411 4.29E-94 T 06-07-2017 CAL12_RS23185 a48b7d1f5a4d3b4e4974c9094cc9b0a6 419 Pfam PF01546 Peptidase family M20/M25/M40 85 408 5.8E-36 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS10270 f8a3cc38e217a34d3093a12f37376246 291 Pfam PF04909 Amidohydrolase 28 291 1.3E-36 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS10270 f8a3cc38e217a34d3093a12f37376246 291 Gene3D G3DSA:3.20.20.140 10 291 3.5E-88 T 06-07-2017 CAL12_RS10270 f8a3cc38e217a34d3093a12f37376246 291 SUPERFAMILY SSF51556 23 291 5.92E-69 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 444 1.8E-15 T 06-07-2017 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 Gene3D G3DSA:3.60.15.10 3 101 2.8E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 Gene3D G3DSA:3.60.15.10 136 255 2.8E-46 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 SUPERFAMILY SSF56281 2 452 1.85E-127 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 Pfam PF00753 Metallo-beta-lactamase superfamily 19 195 5.5E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 SMART SM01027 248 367 4.0E-47 T 06-07-2017 IPR022712 Beta-Casp domain CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 SMART SM00849 14 236 2.0E-7 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24525 0a4ea88fe437ddc76e4a2f8c9cdd088c 452 Pfam PF10996 Beta-Casp domain 248 367 3.7E-22 T 06-07-2017 IPR022712 Beta-Casp domain CAL12_RS13505 6f049806ca1b26aee91115b697f30edf 100 Gene3D G3DSA:1.10.10.10 15 92 2.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13505 6f049806ca1b26aee91115b697f30edf 100 SMART SM00418 16 97 1.6E-11 T 06-07-2017 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CAL12_RS13505 6f049806ca1b26aee91115b697f30edf 100 Pfam PF12840 Helix-turn-helix domain 16 68 1.7E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13505 6f049806ca1b26aee91115b697f30edf 100 SUPERFAMILY SSF46785 2 91 1.92E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 Gene3D G3DSA:3.40.710.10 32 284 2.0E-81 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 SUPERFAMILY SSF56601 32 284 3.24E-63 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 PRINTS PR00118 Beta-lactamase class A signature 106 131 1.7E-37 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 PRINTS PR00118 Beta-lactamase class A signature 32 56 1.7E-37 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 PRINTS PR00118 Beta-lactamase class A signature 142 166 1.7E-37 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 PRINTS PR00118 Beta-lactamase class A signature 63 80 1.7E-37 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 PRINTS PR00118 Beta-lactamase class A signature 219 234 1.7E-37 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 ProSitePatterns PS00146 Beta-lactamase class-A active site. 65 80 - T 06-07-2017 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CAL12_RS16730 179209688a2e12c64d0d8c7209ed0834 290 Pfam PF13354 Beta-lactamase enzyme family 53 258 1.8E-29 T 06-07-2017 CAL12_RS08195 d636d9616fe427194e39d61f41a297c2 405 Gene3D G3DSA:3.40.50.2300 159 305 1.5E-16 T 06-07-2017 CAL12_RS08195 d636d9616fe427194e39d61f41a297c2 405 Gene3D G3DSA:3.40.50.2300 306 356 9.6E-34 T 06-07-2017 CAL12_RS08195 d636d9616fe427194e39d61f41a297c2 405 Gene3D G3DSA:3.40.50.2300 29 156 9.6E-34 T 06-07-2017 CAL12_RS08195 d636d9616fe427194e39d61f41a297c2 405 Pfam PF13458 Periplasmic binding protein 33 368 1.6E-89 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS08195 d636d9616fe427194e39d61f41a297c2 405 SUPERFAMILY SSF53822 33 403 3.77E-90 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS14600 8a4e0a0cace029d2196ad5c33a5730c0 360 SUPERFAMILY SSF89733 6 343 4.71E-105 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS14600 8a4e0a0cace029d2196ad5c33a5730c0 360 Gene3D G3DSA:3.30.1370.60 76 277 1.2E-76 T 06-07-2017 CAL12_RS14600 8a4e0a0cace029d2196ad5c33a5730c0 360 Pfam PF02615 Malate/L-lactate dehydrogenase 9 336 9.3E-117 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS14600 8a4e0a0cace029d2196ad5c33a5730c0 360 Gene3D G3DSA:1.10.1530.10 7 75 1.1E-23 T 06-07-2017 CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 7.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 7.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 161 7.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 7.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 SUPERFAMILY SSF51735 2 196 2.07E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 171 3.7E-15 T 06-07-2017 CAL12_RS02515 18a42d9df1368a35db4d403a2643ed7f 198 Gene3D G3DSA:3.40.50.720 1 197 1.0E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 ProSitePatterns PS01071 grpE protein signature. 136 178 - T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 Hamap MF_01151 Protein GrpE [grpE]. 4 180 18.678 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 SUPERFAMILY SSF58014 30 122 1.57E-23 T 06-07-2017 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 Gene3D G3DSA:2.30.22.10 127 181 9.6E-23 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 SUPERFAMILY SSF51064 127 181 2.35E-16 T 06-07-2017 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 Pfam PF01025 GrpE 26 179 9.4E-47 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 PRINTS PR00773 GrpE protein signature 80 95 2.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 PRINTS PR00773 GrpE protein signature 159 178 2.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 PRINTS PR00773 GrpE protein signature 133 148 2.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 PRINTS PR00773 GrpE protein signature 52 68 2.0E-24 T 06-07-2017 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS06230 0abdd5bb0335c392136e00eb9289e01f 184 Gene3D G3DSA:3.90.20.20 30 122 1.4E-27 T 06-07-2017 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CAL12_RS21485 29abf684e772e7b908291379d11c2eba 289 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 63 2.5E-8 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS21485 29abf684e772e7b908291379d11c2eba 289 Gene3D G3DSA:1.10.3720.10 77 283 2.6E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21485 29abf684e772e7b908291379d11c2eba 289 SUPERFAMILY SSF161098 81 286 1.19E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21485 29abf684e772e7b908291379d11c2eba 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 287 7.3E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16645 2f4317ae3351b605669f4356addb47f3 219 Pfam PF13578 Methyltransferase domain 82 185 6.8E-15 T 06-07-2017 CAL12_RS16645 2f4317ae3351b605669f4356addb47f3 219 SUPERFAMILY SSF53335 44 190 7.94E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS16645 2f4317ae3351b605669f4356addb47f3 219 Gene3D G3DSA:3.40.50.150 55 198 1.2E-39 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS27460 dabea4512f30c8ce967f2fe0da0724f7 667 Pfam PF05140 ResB-like family 1 656 1.2E-151 T 06-07-2017 IPR007816 ResB-like domain CAL12_RS13580 0c50c35e8970f200ee1dbf7b555442c8 193 Pfam PF06684 Amino acid synthesis 6 179 8.0E-68 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAL12_RS13580 0c50c35e8970f200ee1dbf7b555442c8 193 Gene3D G3DSA:3.30.1330.110 3 193 3.0E-73 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAL12_RS13580 0c50c35e8970f200ee1dbf7b555442c8 193 SUPERFAMILY SSF160519 4 193 5.1E-68 T 06-07-2017 IPR009569 Amino acid synthesis, putative CAL12_RS25735 64c2e2910a38dab4e447068887bee078 503 Gene3D G3DSA:3.40.50.1820 5 489 8.8E-140 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25735 64c2e2910a38dab4e447068887bee078 503 SUPERFAMILY SSF53474 9 483 1.66E-118 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25735 64c2e2910a38dab4e447068887bee078 503 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 06-07-2017 IPR019826 Carboxylesterase type B, active site CAL12_RS25735 64c2e2910a38dab4e447068887bee078 503 Pfam PF00135 Carboxylesterase family 9 483 2.2E-106 T 06-07-2017 IPR002018 Carboxylesterase, type B CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 Gene3D G3DSA:3.90.230.10 159 347 2.4E-37 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 Gene3D G3DSA:3.40.350.10 16 158 1.3E-24 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 SUPERFAMILY SSF55920 157 370 6.54E-42 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 Pfam PF00557 Metallopeptidase family M24 168 360 8.7E-30 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 SUPERFAMILY SSF53092 15 158 1.48E-23 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAL12_RS07680 4816c3f15c2ff104f0c915e595535466 386 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 160 1.2E-20 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAL12_RS21385 f06f9e91a62d486bb83205adb8d97e9d 197 SUPERFAMILY SSF46689 8 72 1.23E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21385 f06f9e91a62d486bb83205adb8d97e9d 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 8.3E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS21385 f06f9e91a62d486bb83205adb8d97e9d 197 Gene3D G3DSA:1.10.357.10 1 180 8.8E-30 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS21385 f06f9e91a62d486bb83205adb8d97e9d 197 SUPERFAMILY SSF48498 78 180 3.56E-16 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 SUPERFAMILY SSF52540 56 318 2.83E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 SMART SM00382 55 246 4.7E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 247 332 8.8E-25 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 Pfam PF00005 ABC transporter 47 196 3.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 Gene3D G3DSA:3.40.50.300 21 270 1.3E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21495 0d0b4f9bd3f3b05f6c102571330b2e8c 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 313 2.1E-16 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS14935 21e56a979b8ad1d1adbef42cd521eac4 216 Gene3D G3DSA:3.90.10.10 116 168 3.3E-14 T 06-07-2017 CAL12_RS14935 21e56a979b8ad1d1adbef42cd521eac4 216 Gene3D G3DSA:3.90.10.10 204 215 3.3E-14 T 06-07-2017 CAL12_RS14935 21e56a979b8ad1d1adbef42cd521eac4 216 SUPERFAMILY SSF48695 18 179 5.42E-37 T 06-07-2017 IPR011031 Multihaem cytochrome CAL12_RS14935 21e56a979b8ad1d1adbef42cd521eac4 216 Pfam PF14522 Cytochrome c7 and related cytochrome c 124 216 2.0E-8 T 06-07-2017 CAL12_RS14935 21e56a979b8ad1d1adbef42cd521eac4 216 Gene3D G3DSA:3.90.10.10 43 90 1.7E-7 T 06-07-2017 CAL12_RS26565 6969d5f8dd83cb5aa4dfaa0044287a3a 400 Gene3D G3DSA:3.40.50.150 104 166 1.4E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26565 6969d5f8dd83cb5aa4dfaa0044287a3a 400 SUPERFAMILY SSF53335 22 68 1.63E-5 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26565 6969d5f8dd83cb5aa4dfaa0044287a3a 400 SUPERFAMILY SSF53335 81 392 1.67E-80 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26565 6969d5f8dd83cb5aa4dfaa0044287a3a 400 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 97 328 4.0E-52 T 06-07-2017 IPR003788 Putative S-adenosyl-L-methionine-dependent methyltransferase MidA Reactome: R-HSA-6799198 CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 7.7E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 7.7E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 7.7E-9 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 282 1.6E-47 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 Gene3D G3DSA:2.120.10.30 40 304 8.3E-67 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS13385 1bcb94e7b37c15f97de51ec7a7b0b3f5 310 SUPERFAMILY SSF63829 41 300 1.31E-64 T 06-07-2017 CAL12_RS14955 b0a9882f82570834af66e7d72a3a9611 755 Pfam PF00577 Outer membrane usher protein 184 370 1.6E-4 T 06-07-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14955 b0a9882f82570834af66e7d72a3a9611 755 Pfam PF00577 Outer membrane usher protein 421 662 1.0E-21 T 06-07-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS14955 b0a9882f82570834af66e7d72a3a9611 755 Pfam PF13953 PapC C-terminal domain 672 731 1.2E-8 T 06-07-2017 IPR025949 PapC-like, C-terminal domain CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 1.0E-28 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 31.318 T 06-07-2017 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 PIRSF PIRSF006092 1 158 3.1E-52 T 06-07-2017 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 Gene3D G3DSA:1.10.287.180 1 75 4.5E-33 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 Gene3D G3DSA:3.10.50.30 83 157 2.7E-29 T 06-07-2017 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 2.2E-55 T 06-07-2017 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 06-07-2017 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 1.9E-31 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 SUPERFAMILY SSF46557 4 77 3.01E-26 T 06-07-2017 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CAL12_RS06535 0a521b9df77c04cd6301fe8bb3d2ae9e 158 SUPERFAMILY SSF54534 83 157 1.44E-23 T 06-07-2017 CAL12_RS27070 424346e8091a1ae6ef06acb6d6b53fc4 115 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 3.5E-22 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS27070 424346e8091a1ae6ef06acb6d6b53fc4 115 SMART SM00834 1 42 4.4E-19 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS27070 424346e8091a1ae6ef06acb6d6b53fc4 115 Pfam PF09723 Zinc ribbon domain 1 41 1.0E-16 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 SUPERFAMILY SSF51604 115 365 4.98E-62 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 SMART SM00922 150 242 1.5E-25 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 191 222 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 Pfam PF13378 Enolase C-terminal domain-like 157 358 3.3E-54 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 126 6.0E-18 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 Gene3D G3DSA:3.30.390.10 1 134 4.5E-38 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 SUPERFAMILY SSF54826 1 126 2.25E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS08895 d4de9aa6340b18c14af6797f8dee39c3 367 Gene3D G3DSA:3.20.20.120 135 365 1.1E-61 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 Pfam PF07729 FCD domain 82 203 3.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 SUPERFAMILY SSF46785 5 76 2.02E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 SMART SM00895 82 205 2.6E-11 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 SUPERFAMILY SSF48008 79 212 6.8E-16 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 1.4E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 Gene3D G3DSA:1.10.10.10 5 73 5.0E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 Gene3D G3DSA:1.20.120.530 78 212 1.4E-14 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS24015 123b062fac0d9e78ea62a30466a5d393 216 SMART SM00345 14 72 2.9E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 Pfam PF00149 Calcineurin-like phosphoesterase 4 140 1.1E-8 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 PIRSF PIRSF000903 3 273 9.5E-102 T 06-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 3 271 43.656 T 06-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 5 264 6.8E-72 T 06-07-2017 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 Gene3D G3DSA:3.60.21.10 170 268 5.2E-49 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 Gene3D G3DSA:3.60.21.10 4 133 5.2E-49 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS24945 3f56a59fa09a55f40efacac22a0c9e45 277 SUPERFAMILY SSF56300 3 258 1.65E-48 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 Gene3D G3DSA:2.60.260.20 118 205 3.0E-22 T 06-07-2017 CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 SUPERFAMILY SSF49493 210 287 4.06E-16 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 SUPERFAMILY SSF49493 120 217 1.05E-19 T 06-07-2017 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 Gene3D G3DSA:1.10.287.110 1 111 4.5E-27 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 Pfam PF00226 DnaJ domain 5 66 2.1E-22 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 Gene3D G3DSA:2.60.260.20 207 281 1.1E-14 T 06-07-2017 CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 PRINTS PR00625 DnaJ domain signature 61 80 5.3E-20 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 PRINTS PR00625 DnaJ domain signature 25 40 5.3E-20 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 PRINTS PR00625 DnaJ domain signature 41 61 5.3E-20 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 PRINTS PR00625 DnaJ domain signature 7 25 5.3E-20 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 SMART SM00271 4 61 4.0E-25 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 Pfam PF01556 DnaJ C terminal domain 129 281 4.8E-32 T 06-07-2017 IPR002939 Chaperone DnaJ, C-terminal CAL12_RS05035 ccab2f436c55d94ab362851207d88aab 309 SUPERFAMILY SSF46565 1 83 4.06E-27 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS09005 185416ccf292cd30d7237d7530a4a118 139 PIRSF PIRSF008546 1 139 6.3E-52 T 06-07-2017 IPR014937 Protein of unknown function DUF1810 CAL12_RS09005 185416ccf292cd30d7237d7530a4a118 139 Pfam PF08837 Protein of unknown function (DUF1810) 5 139 8.2E-54 T 06-07-2017 IPR014937 Protein of unknown function DUF1810 CAL12_RS09005 185416ccf292cd30d7237d7530a4a118 139 SUPERFAMILY SSF140736 3 139 6.15E-55 T 06-07-2017 CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 SMART SM00843 718 783 4.8E-38 T 06-07-2017 IPR018541 FtsK gamma domain CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 SMART SM00382 438 633 0.0077 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 Pfam PF09397 Ftsk gamma domain 720 780 1.3E-26 T 06-07-2017 IPR018541 FtsK gamma domain CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 Gene3D G3DSA:3.40.50.300 376 679 4.6E-97 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 Pfam PF01580 FtsK/SpoIIIE family 403 612 1.2E-64 T 06-07-2017 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 SUPERFAMILY SSF52540 390 684 1.73E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 SUPERFAMILY SSF46785 718 782 1.36E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21545 ab1a10e74c6f950077dc1f5e3547b2a5 788 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 28 215 4.9E-44 T 06-07-2017 IPR025199 DNA translocase FtsK, 4TM region CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 Pfam PF13604 AAA domain 517 704 6.1E-42 T 06-07-2017 CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 Gene3D G3DSA:3.40.50.300 510 686 7.1E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 Gene3D G3DSA:3.40.50.300 701 765 8.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 Gene3D G3DSA:3.40.50.300 893 950 8.5E-7 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 SUPERFAMILY SSF52540 513 661 3.88E-14 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 Pfam PF08751 TrwC relaxase 12 292 6.5E-76 T 06-07-2017 IPR014862 TrwC relaxase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 SUPERFAMILY SSF55464 5 296 1.19E-72 T 06-07-2017 CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 15 296 3.7E-68 T 06-07-2017 IPR014059 Conjugative relaxase, N-terminal CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 SUPERFAMILY SSF52540 839 960 4.33E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 SUPERFAMILY SSF52540 726 758 4.33E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20295 a7d34cdae56caefba96e51b4d5b38b70 994 SUPERFAMILY SSF52540 629 687 4.33E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16350 c2876e0d254f2dd52abbb127154f8755 377 Gene3D G3DSA:3.40.50.300 16 239 2.7E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16350 c2876e0d254f2dd52abbb127154f8755 377 SUPERFAMILY SSF52540 23 248 2.73E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16350 c2876e0d254f2dd52abbb127154f8755 377 Pfam PF00005 ABC transporter 27 167 9.7E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS16350 c2876e0d254f2dd52abbb127154f8755 377 SMART SM00382 33 217 2.5E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS16350 c2876e0d254f2dd52abbb127154f8755 377 SUPERFAMILY SSF50331 242 335 1.87E-12 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS24570 89f5754f1391a12125771da4ab8b8ab8 167 Gene3D G3DSA:3.10.129.10 14 158 7.2E-25 T 06-07-2017 IPR029069 HotDog domain CAL12_RS24570 89f5754f1391a12125771da4ab8b8ab8 167 SUPERFAMILY SSF54637 14 156 1.87E-24 T 06-07-2017 IPR029069 HotDog domain CAL12_RS24570 89f5754f1391a12125771da4ab8b8ab8 167 Pfam PF01575 MaoC like domain 28 126 6.3E-11 T 06-07-2017 IPR002539 MaoC-like domain CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 SUPERFAMILY SSF56801 3 528 7.59E-152 T 06-07-2017 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Gene3D G3DSA:3.40.50.980 19 185 2.5E-38 T 06-07-2017 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Pfam PF00501 AMP-binding enzyme 22 430 5.1E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Gene3D G3DSA:3.30.300.30 426 527 1.2E-29 T 06-07-2017 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Gene3D G3DSA:2.30.38.10 349 424 1.1E-21 T 06-07-2017 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 180 191 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Gene3D G3DSA:3.40.50.980 186 340 5.1E-27 T 06-07-2017 CAL12_RS21650 bb0ad1a015bbdb88cfb8f05513cc48aa 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 518 6.2E-20 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 Pfam PF00263 Bacterial type II and III secretion system protein 584 750 1.4E-49 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 PRINTS PR00811 Bacterial general secretion pathway protein D signature 495 505 4.2E-30 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 PRINTS PR00811 Bacterial general secretion pathway protein D signature 737 751 4.2E-30 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 PRINTS PR00811 Bacterial general secretion pathway protein D signature 714 732 4.2E-30 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 PRINTS PR00811 Bacterial general secretion pathway protein D signature 580 604 4.2E-30 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 PRINTS PR00811 Bacterial general secretion pathway protein D signature 615 625 4.2E-30 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 124 759 3.6E-195 T 06-07-2017 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 Pfam PF03958 Bacterial type II/III secretion system short domain 220 279 1.5E-12 T 06-07-2017 IPR005644 NolW-like CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 Pfam PF03958 Bacterial type II/III secretion system short domain 358 495 1.8E-13 T 06-07-2017 IPR005644 NolW-like CAL12_RS27350 b3e97a5760ff306d1087fccee7d45cf9 933 Pfam PF03958 Bacterial type II/III secretion system short domain 285 353 4.9E-13 T 06-07-2017 IPR005644 NolW-like CAL12_RS19540 a02ee18b3e3b7c853dfc7557014f9168 194 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 3 177 1.0E-53 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAL12_RS19540 a02ee18b3e3b7c853dfc7557014f9168 194 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 2 179 18.507 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAL12_RS19540 a02ee18b3e3b7c853dfc7557014f9168 194 Pfam PF04279 Intracellular septation protein A 3 177 3.2E-66 T 06-07-2017 IPR006008 Intracellular septation protein A GO:0016021 CAL12_RS13250 864ab51497debd6d6c230213fe01c588 292 Pfam PF00691 OmpA family 178 276 4.9E-19 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS13250 864ab51497debd6d6c230213fe01c588 292 Gene3D G3DSA:3.30.1330.60 159 282 1.5E-32 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS13250 864ab51497debd6d6c230213fe01c588 292 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 52 77 1.1E-7 T 06-07-2017 IPR025713 Motility protein B, N-terminal domain CAL12_RS13250 864ab51497debd6d6c230213fe01c588 292 SUPERFAMILY SSF103088 160 281 6.41E-29 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS27175 326b6622425f6cc0bc28cbe0d75b513d 446 Pfam PF13657 HipA N-terminal domain 8 108 7.7E-23 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS27175 326b6622425f6cc0bc28cbe0d75b513d 446 Pfam PF07804 HipA-like C-terminal domain 252 408 2.5E-30 T 06-07-2017 IPR012893 HipA-like, C-terminal CAL12_RS27175 326b6622425f6cc0bc28cbe0d75b513d 446 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 7 108 7.9E-27 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS27175 326b6622425f6cc0bc28cbe0d75b513d 446 Pfam PF07805 HipA-like N-terminal domain 156 242 8.5E-22 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 Pfam PF09209 Domain of unknown function (DUF1956) 107 227 1.5E-15 T 06-07-2017 IPR015292 Transcription regulator YbiH, C-terminal CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 Gene3D G3DSA:1.10.357.10 63 232 1.4E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.6E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 SUPERFAMILY SSF46689 16 90 7.98E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 Gene3D G3DSA:1.10.10.60 16 62 5.4E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.8E-14 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS13035 8170a6bc40829d9e095d6712b92c63a6 245 SUPERFAMILY SSF48498 99 229 1.38E-17 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 Gene3D G3DSA:3.20.20.360 71 407 2.7E-118 T 06-07-2017 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 PIRSF PIRSF001363 1 527 7.6E-248 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 SUPERFAMILY SSF51645 6 527 2.62E-190 T 06-07-2017 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 Gene3D G3DSA:1.20.1220.12 411 521 3.1E-32 T 06-07-2017 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 527 2.7E-231 T 06-07-2017 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 06-07-2017 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS09030 c5ec584453236c0b4f914f100b15c811 527 Pfam PF01274 Malate synthase 13 527 1.3E-200 T 06-07-2017 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 SUPERFAMILY SSF51569 4 289 1.47E-82 T 06-07-2017 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 SMART SM01130 5 293 4.1E-85 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 PIRSF PIRSF001365 2 303 3.5E-78 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 Pfam PF00701 Dihydrodipicolinate synthetase family 7 291 7.4E-57 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 2.4E-12 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24010 3a13d73b0e4e8d35efdafb566970f1ba 309 Gene3D G3DSA:3.20.20.70 4 290 1.5E-89 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 Pfam PF01380 SIS domain 136 260 1.5E-17 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 Gene3D G3DSA:1.10.10.10 7 81 3.0E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 Gene3D G3DSA:3.40.50.10490 107 267 4.1E-25 T 06-07-2017 CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 SUPERFAMILY SSF46689 7 81 9.86E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 SUPERFAMILY SSF53697 106 274 1.53E-24 T 06-07-2017 CAL12_RS08600 6c6057ec77bc3405938f37022509d819 293 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 79 3.6E-15 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 SUPERFAMILY SSF51735 6 263 5.89E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 262 1.4E-65 T 06-07-2017 CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 Gene3D G3DSA:3.40.50.720 1 264 9.8E-81 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.4E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03480 771b353555399c4eb36a405395ddde07 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09185 c9aa98a76f7d1c38cbbb11c8d3f42936 86 SUPERFAMILY SSF54565 1 76 1.96E-27 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09185 c9aa98a76f7d1c38cbbb11c8d3f42936 86 Pfam PF00886 Ribosomal protein S16 8 68 3.9E-24 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09185 c9aa98a76f7d1c38cbbb11c8d3f42936 86 Gene3D G3DSA:3.30.1320.10 1 77 6.1E-31 T 06-07-2017 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09185 c9aa98a76f7d1c38cbbb11c8d3f42936 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 4 77 1.5E-26 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS09185 c9aa98a76f7d1c38cbbb11c8d3f42936 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.69 T 06-07-2017 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 SUPERFAMILY SSF51735 6 245 2.07E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 8.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 5.3E-60 T 06-07-2017 CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 Gene3D G3DSA:3.40.50.720 4 245 2.0E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.7E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08290 9376a456401b23a0bdcb8411e0dcfb89 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 3.6E-4 T 06-07-2017 CAL12_RS13255 4eb0c459d2056d43818eb21a68648add 231 SUPERFAMILY SSF56281 5 203 2.94E-50 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS13255 4eb0c459d2056d43818eb21a68648add 231 Gene3D G3DSA:3.60.15.10 4 206 2.7E-55 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS13255 4eb0c459d2056d43818eb21a68648add 231 SMART SM00849 12 175 4.2E-28 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS13255 4eb0c459d2056d43818eb21a68648add 231 Pfam PF00753 Metallo-beta-lactamase superfamily 12 175 3.4E-12 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS24940 bfb5489f15d979bbd38726f0772fddc4 392 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 368 8.9E-87 T 06-07-2017 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 CAL12_RS24940 bfb5489f15d979bbd38726f0772fddc4 392 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 365 4.0E-59 T 06-07-2017 IPR005495 Permease LptG/LptF-related GO:0016021 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 Gene3D G3DSA:3.40.718.10 1 357 1.8E-129 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 51.793 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 2.8E-149 T 06-07-2017 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 9.0E-134 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 SMART SM01329 4 353 1.4E-205 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS09675 1c4c7ffec05f4c813d1692d7cd47aab6 359 SUPERFAMILY SSF53659 1 357 4.8E-121 T 06-07-2017 CAL12_RS25555 b202e2b738218bd944ab5951bcecce98 262 SUPERFAMILY SSF110399 5 246 8.24E-91 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAL12_RS25555 b202e2b738218bd944ab5951bcecce98 262 Hamap MF_00443 Thiazole synthase [thiG]. 6 262 42.147 T 06-07-2017 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CAL12_RS25555 b202e2b738218bd944ab5951bcecce98 262 Gene3D G3DSA:3.20.20.70 14 236 5.3E-55 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS25555 b202e2b738218bd944ab5951bcecce98 262 Pfam PF05690 Thiazole biosynthesis protein ThiG 9 256 1.5E-105 T 06-07-2017 CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 PRINTS PR00601 Bacterioferritin signature 39 58 3.6E-7 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 PRINTS PR00601 Bacterioferritin signature 80 100 3.6E-7 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 PRINTS PR00601 Bacterioferritin signature 170 181 3.6E-7 T 06-07-2017 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 Gene3D G3DSA:1.20.1260.10 35 181 3.2E-52 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 SUPERFAMILY SSF47240 37 181 3.9E-42 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 Pfam PF00210 Ferritin-like domain 46 181 3.8E-32 T 06-07-2017 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CAL12_RS26350 be5ea33311473830eed2e2c134aeff36 181 PIRSF PIRSF018063 19 181 1.8E-61 T 06-07-2017 IPR014490 Uncharacterised conserved protein UCP018063, ferritin fold CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 Gene3D G3DSA:3.40.50.2300 5 130 2.5E-39 T 06-07-2017 CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 Pfam PF00072 Response regulator receiver domain 9 118 2.4E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 Gene3D G3DSA:1.10.10.10 134 232 6.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 SUPERFAMILY SSF52172 4 129 2.42E-41 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 5.0E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 SMART SM00862 154 231 3.5E-24 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 SMART SM00448 6 117 3.3E-39 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05545 27f5d799fb029db7c83f83dd892dbf13 233 SUPERFAMILY SSF46894 136 231 3.68E-24 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS21350 eab35fa6aa08ac032c235c80442f9056 481 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 438 1.0E-165 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAL12_RS21350 eab35fa6aa08ac032c235c80442f9056 481 PIRSF PIRSF006446 2 463 3.8E-218 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAL12_RS23340 b12500279e94dc98e29d3796cee56123 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 249 1.9E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23340 b12500279e94dc98e29d3796cee56123 273 Gene3D G3DSA:1.10.3720.10 58 250 2.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23340 b12500279e94dc98e29d3796cee56123 273 SUPERFAMILY SSF161098 60 245 4.32E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15805 1dc38000af6d05f50f1f6196dbd9fa32 401 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS15805 1dc38000af6d05f50f1f6196dbd9fa32 401 Pfam PF01070 FMN-dependent dehydrogenase 16 379 2.0E-120 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS15805 1dc38000af6d05f50f1f6196dbd9fa32 401 PIRSF PIRSF000138 2 384 5.7E-116 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS15805 1dc38000af6d05f50f1f6196dbd9fa32 401 SUPERFAMILY SSF51395 7 379 6.72E-86 T 06-07-2017 CAL12_RS15805 1dc38000af6d05f50f1f6196dbd9fa32 401 Gene3D G3DSA:3.20.20.70 7 381 1.1E-119 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS25675 f8bc8f68337ff8a92215144abb336f63 413 Gene3D G3DSA:3.40.50.10540 317 407 2.4E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25675 f8bc8f68337ff8a92215144abb336f63 413 Gene3D G3DSA:3.40.50.10540 14 229 2.4E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25675 f8bc8f68337ff8a92215144abb336f63 413 Gene3D G3DSA:3.30.1540.10 236 316 7.3E-31 T 06-07-2017 CAL12_RS25675 f8bc8f68337ff8a92215144abb336f63 413 SUPERFAMILY SSF89796 13 407 6.93E-121 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25675 f8bc8f68337ff8a92215144abb336f63 413 Pfam PF02515 CoA-transferase family III 18 384 2.8E-108 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS08330 71e653222683837e73c522fc091cae45 249 Gene3D G3DSA:3.30.950.10 133 247 2.1E-26 T 06-07-2017 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS08330 71e653222683837e73c522fc091cae45 249 PIRSF PIRSF005917 7 244 2.7E-45 T 06-07-2017 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS08330 71e653222683837e73c522fc091cae45 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 18 227 1.4E-9 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS08330 71e653222683837e73c522fc091cae45 249 SUPERFAMILY SSF53790 16 246 4.19E-64 T 06-07-2017 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CAL12_RS10730 1cc4e1bd901d7d87b663b6745b768cdd 647 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 294 2.9E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS10730 1cc4e1bd901d7d87b663b6745b768cdd 647 Pfam PF02653 Branched-chain amino acid transport system / permease component 353 610 2.7E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS04205 0d74079fa9dc2afb57afc8a68ef8094f 69 Pfam PF11160 Protein of unknown function (DUF2945) 7 67 1.5E-23 T 06-07-2017 IPR021331 Protein of unknown function DUF2945 CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 SUPERFAMILY SSF46785 2 113 2.92E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 Gene3D G3DSA:3.40.190.10 92 182 1.9E-12 T 06-07-2017 CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.9E-12 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 SUPERFAMILY SSF53850 93 301 9.77E-34 T 06-07-2017 CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 Gene3D G3DSA:1.10.10.10 4 89 1.4E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 Gene3D G3DSA:3.40.190.10 183 266 1.6E-20 T 06-07-2017 CAL12_RS00390 6536b2f5f88faff8caf93e3f4fa26ab3 307 Pfam PF03466 LysR substrate binding domain 92 297 7.4E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10260 f70af6bd1209eccb5096d2bb3ad41ef1 271 Gene3D G3DSA:2.40.30.10 11 134 8.3E-36 T 06-07-2017 CAL12_RS10260 f70af6bd1209eccb5096d2bb3ad41ef1 271 Pfam PF04954 Siderophore-interacting protein 143 261 8.9E-41 T 06-07-2017 IPR007037 Siderophore-interacting protein CAL12_RS10260 f70af6bd1209eccb5096d2bb3ad41ef1 271 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 135 1.2E-37 T 06-07-2017 IPR013113 FAD-binding 9, siderophore-interacting CAL12_RS10260 f70af6bd1209eccb5096d2bb3ad41ef1 271 SUPERFAMILY SSF63380 8 138 7.75E-14 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS10260 f70af6bd1209eccb5096d2bb3ad41ef1 271 Gene3D G3DSA:3.40.50.80 138 264 6.9E-47 T 06-07-2017 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 Pfam PF01138 3' exoribonuclease family, domain 1 18 148 1.9E-21 T 06-07-2017 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 Pfam PF03725 3' exoribonuclease family, domain 2 167 230 1.4E-10 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 SUPERFAMILY SSF54211 6 189 6.58E-47 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 10 244 1.8E-116 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 Gene3D G3DSA:3.30.230.70 11 244 2.2E-32 T 06-07-2017 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 Hamap MF_00564 Ribonuclease PH [rph]. 9 245 48.76 T 06-07-2017 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 ProSitePatterns PS01277 Ribonuclease PH signature. 124 136 - T 06-07-2017 IPR018336 Ribonuclease PH, conserved site CAL12_RS15345 ba99d98b2535235be849506490d2a7e3 245 SUPERFAMILY SSF55666 162 244 3.14E-24 T 06-07-2017 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 Gene3D G3DSA:3.40.50.720 20 212 1.0E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PIRSF PIRSF000114 16 360 1.0E-84 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 SUPERFAMILY SSF51735 21 209 2.41E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 SUPERFAMILY SSF48179 208 359 1.26E-46 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 21 350 33.419 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 23 188 6.3E-35 T 06-07-2017 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 202 226 6.3E-36 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 162 182 6.3E-36 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 25 42 6.3E-36 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 267 284 6.3E-36 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 227 251 6.3E-36 T 06-07-2017 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 209 348 8.9E-44 T 06-07-2017 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 CAL12_RS26210 588813da93606e6a51b775b5b2236397 367 Gene3D G3DSA:1.10.1040.10 213 354 2.4E-47 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Pfam PF00012 Hsp70 protein 298 394 2.7E-9 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Pfam PF00012 Hsp70 protein 103 230 1.5E-10 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 SUPERFAMILY SSF53067 179 247 4.64E-33 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 SUPERFAMILY SSF53067 296 417 4.64E-33 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 SUPERFAMILY SSF53067 9 175 8.01E-30 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 PRINTS PR00301 70kDa heat shock protein signature 8 21 8.3E-7 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 PRINTS PR00301 70kDa heat shock protein signature 190 200 8.3E-7 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 PRINTS PR00301 70kDa heat shock protein signature 36 48 8.3E-7 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 PRINTS PR00301 70kDa heat shock protein signature 124 144 8.3E-7 T 06-07-2017 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Gene3D G3DSA:3.30.420.40 105 188 3.7E-30 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Gene3D G3DSA:3.30.420.40 8 72 3.7E-30 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Gene3D G3DSA:3.30.420.40 356 396 1.2E-13 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 Gene3D G3DSA:3.30.420.40 189 225 1.2E-13 T 06-07-2017 CAL12_RS03600 a6d834026f7503cb80f22dde669ceee3 422 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 184 197 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 Gene3D G3DSA:1.20.1250.20 479 503 1.6E-19 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 Gene3D G3DSA:1.20.1250.20 261 426 1.6E-19 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 Gene3D G3DSA:1.20.1250.20 9 187 4.6E-23 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 493 5.9E-119 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 Pfam PF07690 Major Facilitator Superfamily 14 407 4.7E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 158 182 1.9E-5 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 1.9E-5 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.9E-5 T 06-07-2017 CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 SUPERFAMILY SSF103473 8 191 1.44E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 SUPERFAMILY SSF103473 474 501 1.44E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01610 5dd381704a0f4521498713c4b1eea48c 511 SUPERFAMILY SSF103473 246 417 1.44E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12765 8b6b792f7b00702ce2919ff40fa1dbef 336 Gene3D G3DSA:3.60.130.10 41 330 6.8E-41 T 06-07-2017 CAL12_RS12765 8b6b792f7b00702ce2919ff40fa1dbef 336 SUPERFAMILY SSF51197 43 329 1.97E-51 T 06-07-2017 CAL12_RS12765 8b6b792f7b00702ce2919ff40fa1dbef 336 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 69 325 4.6E-34 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS16540 b396c34f697932c924a553911f33797d 116 Pfam PF12680 SnoaL-like domain 11 107 1.2E-17 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS16540 b396c34f697932c924a553911f33797d 116 SUPERFAMILY SSF54427 4 111 1.76E-24 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS16540 b396c34f697932c924a553911f33797d 116 Gene3D G3DSA:3.10.450.50 1 112 7.1E-23 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS20680 ffe08b05a35d33a94ffa5b427bf6a110 382 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 102 377 4.9E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20680 ffe08b05a35d33a94ffa5b427bf6a110 382 SUPERFAMILY SSF53850 147 349 3.47E-7 T 06-07-2017 CAL12_RS08135 fee649d96bedde69fa84cf6aca15a0a6 157 PIRSF PIRSF032131 1 155 3.6E-43 T 06-07-2017 IPR009562 Protein of unknown function DUF1178 CAL12_RS08135 fee649d96bedde69fa84cf6aca15a0a6 157 Pfam PF06676 Protein of unknown function (DUF1178) 1 149 1.2E-51 T 06-07-2017 IPR009562 Protein of unknown function DUF1178 CAL12_RS11085 fbdb2f843eb4f0286aab0c37788c9a7a 315 Pfam PF13523 Acetyltransferase (GNAT) domain 137 279 6.3E-53 T 06-07-2017 CAL12_RS11085 fbdb2f843eb4f0286aab0c37788c9a7a 315 SUPERFAMILY SSF55729 97 293 1.2E-64 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS11085 fbdb2f843eb4f0286aab0c37788c9a7a 315 SMART SM01006 131 178 2.3E-18 T 06-07-2017 IPR019432 Siderophore biosynthesis protein, conserved domain CAL12_RS11085 fbdb2f843eb4f0286aab0c37788c9a7a 315 Gene3D G3DSA:3.40.630.30 108 298 7.7E-69 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 Pfam PF00677 Lumazine binding domain 3 90 3.1E-14 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 Pfam PF00677 Lumazine binding domain 103 191 1.7E-20 T 06-07-2017 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 Gene3D G3DSA:2.40.30.20 5 107 2.2E-22 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 Gene3D G3DSA:2.40.30.20 108 202 1.5E-30 T 06-07-2017 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 PIRSF PIRSF000498 1 208 1.7E-65 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 1.8E-53 T 06-07-2017 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 SUPERFAMILY SSF63380 1 95 1.45E-16 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS24690 97df6263e89cba2af1dd9ee7d7722fa8 212 SUPERFAMILY SSF63380 97 203 1.36E-31 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 Pfam PF04055 Radical SAM superfamily 99 258 8.7E-15 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 Hamap MF_00206 Lipoyl synthase [lipA]. 1 329 156.548 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 Gene3D G3DSA:3.20.20.70 61 322 1.4E-73 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 TIGRFAM TIGR00510 lipA: lipoyl synthase 40 322 7.5E-131 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 PIRSF PIRSF005963 2 329 1.7E-130 T 06-07-2017 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 23 81 9.2E-9 T 06-07-2017 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 SMART SM00729 92 301 1.0E-15 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS26770 8de431b179901ad70bbcce4d829f0f27 329 SUPERFAMILY SSF102114 60 324 1.19E-68 T 06-07-2017 CAL12_RS05145 9b8e01fa438294860e5f90c85e1f37fd 215 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 24 212 2.9E-54 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAL12_RS05145 9b8e01fa438294860e5f90c85e1f37fd 215 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 23 214 2.9E-62 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAL12_RS05145 9b8e01fa438294860e5f90c85e1f37fd 215 PIRSF PIRSF020680 16 215 3.3E-63 T 06-07-2017 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 CAL12_RS05145 9b8e01fa438294860e5f90c85e1f37fd 215 SUPERFAMILY SSF159709 31 214 1.06E-54 T 06-07-2017 CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 SUPERFAMILY SSF56176 1 174 6.54E-47 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 SUPERFAMILY SSF55447 178 272 8.9E-16 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 Gene3D G3DSA:3.30.465.10 59 174 3.1E-31 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 SMART SM01092 181 271 8.2E-12 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 Gene3D G3DSA:3.30.43.10 1 54 1.4E-21 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 5.6E-43 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS15835 71ec7f1930ce620221524aa288a71986 277 Gene3D G3DSA:3.30.390.50 178 274 8.7E-15 T 06-07-2017 CAL12_RS11850 06d09b7d3ef852a54d2d68ee9340ecd4 129 Gene3D G3DSA:3.40.50.2300 4 126 3.2E-39 T 06-07-2017 CAL12_RS11850 06d09b7d3ef852a54d2d68ee9340ecd4 129 SUPERFAMILY SSF52172 4 125 1.38E-36 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS11850 06d09b7d3ef852a54d2d68ee9340ecd4 129 SMART SM00448 6 120 3.8E-37 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11850 06d09b7d3ef852a54d2d68ee9340ecd4 129 Pfam PF00072 Response regulator receiver domain 8 120 1.4E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS24830 75e75826b1ceda20fdf9640af768d1f9 393 Pfam PF00268 Ribonucleotide reductase, small chain 73 360 2.7E-82 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS24830 75e75826b1ceda20fdf9640af768d1f9 393 SUPERFAMILY SSF47240 57 364 1.58E-96 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS24830 75e75826b1ceda20fdf9640af768d1f9 393 Gene3D G3DSA:1.10.620.20 57 367 1.3E-109 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAL12_RS24830 75e75826b1ceda20fdf9640af768d1f9 393 PIRSF PIRSF000355 44 393 6.6E-131 T 06-07-2017 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 SUPERFAMILY SSF51735 44 209 7.65E-14 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 44 346 1.1E-60 T 06-07-2017 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 Gene3D G3DSA:3.40.50.720 42 228 3.7E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 Pfam PF02558 Ketopantoate reductase PanE/ApbA 45 193 6.1E-27 T 06-07-2017 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 SUPERFAMILY SSF48179 220 344 7.48E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 Gene3D G3DSA:1.10.1040.10 229 344 2.9E-26 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS05825 b1632a808a9db1ac73056d3a10217d27 372 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 221 344 5.8E-25 T 06-07-2017 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CAL12_RS14175 1945ff0926d065c0084f71eef2657bea 272 Gene3D G3DSA:3.40.50.1820 44 262 7.7E-26 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14175 1945ff0926d065c0084f71eef2657bea 272 Pfam PF12697 Alpha/beta hydrolase family 45 255 7.7E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS14175 1945ff0926d065c0084f71eef2657bea 272 SUPERFAMILY SSF53474 163 260 2.11E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14175 1945ff0926d065c0084f71eef2657bea 272 SUPERFAMILY SSF53474 37 134 2.11E-25 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 Pfam PF03466 LysR substrate binding domain 97 302 1.1E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 Gene3D G3DSA:3.40.190.10 188 269 8.0E-7 T 06-07-2017 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 Gene3D G3DSA:1.10.10.10 13 95 1.7E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 SUPERFAMILY SSF53850 97 305 1.66E-41 T 06-07-2017 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 72 1.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 SUPERFAMILY SSF46785 11 118 1.48E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 6.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 6.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 6.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13520 e6352e28222737cad65c28bd59975a11 311 Gene3D G3DSA:3.40.190.10 101 187 1.0E-18 T 06-07-2017 CAL12_RS14785 3b8c59cba9b6b3ae97d8627adf2df768 83 SUPERFAMILY SSF143120 1 51 1.96E-12 T 06-07-2017 CAL12_RS14785 3b8c59cba9b6b3ae97d8627adf2df768 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 58 3.5E-13 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS14785 3b8c59cba9b6b3ae97d8627adf2df768 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 49 5.3E-9 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS14785 3b8c59cba9b6b3ae97d8627adf2df768 83 Gene3D G3DSA:3.40.1620.10 4 47 1.2E-9 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS26340 78e67924c7bdc92abfb859e32832ae21 87 Gene3D G3DSA:1.10.260.40 17 69 3.0E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS26340 78e67924c7bdc92abfb859e32832ae21 87 SUPERFAMILY SSF47413 16 61 2.12E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS26340 78e67924c7bdc92abfb859e32832ae21 87 Pfam PF13560 Helix-turn-helix domain 20 57 5.1E-9 T 06-07-2017 CAL12_RS26340 78e67924c7bdc92abfb859e32832ae21 87 SMART SM00530 17 74 1.2E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS10975 64317ceaa8c83deef4c21623d429420a 183 Gene3D G3DSA:3.90.960.10 10 163 7.1E-30 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS10975 64317ceaa8c83deef4c21623d429420a 183 SUPERFAMILY SSF55826 8 160 3.79E-31 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS10975 64317ceaa8c83deef4c21623d429420a 183 Pfam PF04073 Aminoacyl-tRNA editing domain 32 150 1.4E-22 T 06-07-2017 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CAL12_RS09735 b79eaeb070daedc22801cadae74acd54 115 SUPERFAMILY SSF47226 3 78 1.24E-5 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS09735 b79eaeb070daedc22801cadae74acd54 115 Gene3D G3DSA:1.20.120.160 20 98 7.7E-5 T 06-07-2017 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CAL12_RS01980 0ff318e4cd41dafa19638b2c9f7bea9d 380 SUPERFAMILY SSF56300 3 272 3.24E-37 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS01980 0ff318e4cd41dafa19638b2c9f7bea9d 380 Gene3D G3DSA:3.60.21.10 3 236 1.4E-40 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS01980 0ff318e4cd41dafa19638b2c9f7bea9d 380 Pfam PF00149 Calcineurin-like phosphoesterase 3 164 1.2E-10 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS01980 0ff318e4cd41dafa19638b2c9f7bea9d 380 PIRSF PIRSF033093 1 370 1.8E-90 T 06-07-2017 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type CAL12_RS17890 60e8c355f450c062bf77c1efee2a0f05 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.706 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17890 60e8c355f450c062bf77c1efee2a0f05 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 5.3E-47 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17890 60e8c355f450c062bf77c1efee2a0f05 156 SUPERFAMILY SSF75217 2 154 1.2E-46 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS17890 60e8c355f450c062bf77c1efee2a0f05 156 Gene3D G3DSA:3.40.1280.10 2 155 1.7E-52 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS17890 60e8c355f450c062bf77c1efee2a0f05 156 PIRSF PIRSF004505 1 155 6.6E-44 T 06-07-2017 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 Gene3D G3DSA:1.10.10.10 1 80 3.8E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 Gene3D G3DSA:3.40.190.10 81 201 1.8E-14 T 06-07-2017 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 Pfam PF03466 LysR substrate binding domain 88 204 5.5E-20 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 SUPERFAMILY SSF46785 1 83 6.33E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17015 c49ea6ba7fb0a57dafa36bfec6efc32a 227 SUPERFAMILY SSF53850 89 202 4.65E-17 T 06-07-2017 CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 286 4.3E-46 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 SUPERFAMILY SSF53850 40 288 3.35E-51 T 06-07-2017 CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 SMART SM00062 67 288 1.3E-39 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 Gene3D G3DSA:3.40.190.10 146 244 2.6E-17 T 06-07-2017 CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 Gene3D G3DSA:3.40.190.10 247 289 8.3E-31 T 06-07-2017 CAL12_RS26315 5d8a856f820a4028fbf4dc03a19482b8 302 Gene3D G3DSA:3.40.190.10 64 145 8.3E-31 T 06-07-2017 CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 SUPERFAMILY SSF141986 136 288 2.09E-40 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 Gene3D G3DSA:3.40.50.10740 5 150 6.6E-36 T 06-07-2017 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 SUPERFAMILY SSF52317 6 153 1.19E-30 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 Pfam PF02016 LD-carboxypeptidase 7 281 1.1E-68 T 06-07-2017 IPR003507 Peptidase family S66 CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 PIRSF PIRSF028757 1 298 4.5E-68 T 06-07-2017 IPR003507 Peptidase family S66 CAL12_RS10920 0910e6e737d82ced0d453a8364c7f856 313 Gene3D G3DSA:3.50.30.60 165 288 6.7E-42 T 06-07-2017 IPR027461 LD-carboxypeptidase A, C-terminal domain CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 Gene3D G3DSA:3.30.565.10 282 441 1.4E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 Gene3D G3DSA:1.10.287.130 208 276 1.2E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 SMART SM00388 215 281 3.5E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 SUPERFAMILY SSF47384 198 280 3.53E-12 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 SUPERFAMILY SSF55874 282 441 2.1E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 443 2.5E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 SMART SM00387 322 445 6.6E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS02725 b423c91e8c6e811193cc38eb31fd3750 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 217 279 5.2E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 SUPERFAMILY SSF51905 301 440 1.51E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 SUPERFAMILY SSF51905 1 204 1.51E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 52 1.8E-6 T 06-07-2017 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 Gene3D G3DSA:3.50.50.60 1 276 3.7E-42 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 SUPERFAMILY SSF54862 442 540 9.54E-27 T 06-07-2017 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 SUPERFAMILY SSF54373 206 300 1.61E-37 T 06-07-2017 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 438 540 5.3E-49 T 06-07-2017 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 Reactome: R-HSA-611105 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 173 188 5.8E-6 T 06-07-2017 CAL12_RS08565 ade16d11d3ca02e083ca3236dd1a3051 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.8E-6 T 06-07-2017 CAL12_RS26910 beee64475eb1d98c4cf272cd3ecff286 446 Gene3D G3DSA:3.40.50.2000 270 411 1.8E-26 T 06-07-2017 CAL12_RS26910 beee64475eb1d98c4cf272cd3ecff286 446 Pfam PF00534 Glycosyl transferases group 1 262 413 8.7E-26 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS26910 beee64475eb1d98c4cf272cd3ecff286 446 SUPERFAMILY SSF53756 211 444 1.41E-57 T 06-07-2017 CAL12_RS26910 beee64475eb1d98c4cf272cd3ecff286 446 SUPERFAMILY SSF53756 1 148 1.41E-57 T 06-07-2017 CAL12_RS26910 beee64475eb1d98c4cf272cd3ecff286 446 Pfam PF13439 Glycosyltransferase Family 4 17 128 8.5E-14 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 PRINTS PR00973 Ribosomal protein S17 family signature 74 81 5.2E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 PRINTS PR00973 Ribosomal protein S17 family signature 32 55 5.2E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 PRINTS PR00973 Ribosomal protein S17 family signature 64 74 5.2E-11 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 64 76 - T 06-07-2017 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 Pfam PF00366 Ribosomal protein S17 18 84 4.3E-31 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 84 5.0E-32 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 SUPERFAMILY SSF50249 12 91 7.28E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 13 84 5.3E-35 T 06-07-2017 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 Gene3D G3DSA:2.40.50.140 12 90 2.8E-33 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27610 c1300ced0bde6abaaf91ea1d5776eca7 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 11 89 24.943 T 06-07-2017 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 Pfam PF07883 Cupin domain 129 194 3.2E-16 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 Pfam PF13560 Helix-turn-helix domain 17 76 1.5E-14 T 06-07-2017 CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 Gene3D G3DSA:2.60.120.10 114 198 4.1E-23 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 SMART SM00530 21 76 7.3E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 Gene3D G3DSA:1.10.260.40 18 113 4.1E-19 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 SUPERFAMILY SSF47413 17 80 3.1E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25525 28f0985d2303a374e3e9be0b5b5eeb4b 200 SUPERFAMILY SSF51182 61 198 3.34E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS27945 db6d0d5b6d370f9b378ce83978444331 281 Pfam PF13460 NAD(P)H-binding 7 179 2.1E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27945 db6d0d5b6d370f9b378ce83978444331 281 Gene3D G3DSA:3.40.50.720 1 215 1.9E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27945 db6d0d5b6d370f9b378ce83978444331 281 SUPERFAMILY SSF51735 2 252 5.83E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 SUPERFAMILY SSF52821 100 233 3.16E-23 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 Gene3D G3DSA:3.40.250.10 109 230 1.4E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 Pfam PF00581 Rhodanese-like domain 120 214 2.3E-5 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 Gene3D G3DSA:3.30.70.100 19 73 6.6E-4 T 06-07-2017 CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 SMART SM00450 119 220 5.6E-9 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02585 32c7804f3b437f95fed04fdcb6861575 285 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 267 33.55 T 06-07-2017 IPR020936 Uncharacterised protein family UPF0176 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 SUPERFAMILY SSF64153 7 242 3.14E-62 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 SUPERFAMILY SSF53613 219 482 8.57E-64 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 206 1.3E-38 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 220 486 19.275 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Gene3D G3DSA:3.40.1190.20 226 483 3.1E-76 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 231 462 1.8E-61 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 PIRSF PIRSF017184 5 485 1.7E-117 T 06-07-2017 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Pfam PF03853 YjeF-related protein N-terminus 29 184 4.0E-39 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Gene3D G3DSA:3.40.50.10260 7 225 8.6E-66 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 426 436 - T 06-07-2017 IPR017953 Carbohydrate kinase, predicted, conserved site CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Pfam PF01256 Carbohydrate kinase 244 462 6.9E-56 T 06-07-2017 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CAL12_RS12620 f8105c25dca1a430a5c511d2185ffe94 499 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 205 23.952 T 06-07-2017 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CAL12_RS02610 d8c6affad1dbb114c933e7a9f0933a79 620 Pfam PF01103 Surface antigen 437 620 2.0E-17 T 06-07-2017 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020 CAL12_RS02610 d8c6affad1dbb114c933e7a9f0933a79 620 Gene3D G3DSA:2.40.160.50 400 431 3.7E-9 T 06-07-2017 CAL12_RS02610 d8c6affad1dbb114c933e7a9f0933a79 620 Gene3D G3DSA:2.40.160.50 472 620 3.7E-9 T 06-07-2017 CAL12_RS09115 ec3412057d1f416666dcb6bef4878319 105 SUPERFAMILY SSF103481 6 103 5.89E-20 T 06-07-2017 CAL12_RS09115 ec3412057d1f416666dcb6bef4878319 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 7.0E-31 T 06-07-2017 IPR000390 Small multidrug resistance protein family GO:0016021 CAL12_RS17815 ff7c5da6197ea4ee1d1d6917c4a060a7 71 Gene3D G3DSA:2.30.30.100 19 70 3.7E-22 T 06-07-2017 CAL12_RS17815 ff7c5da6197ea4ee1d1d6917c4a060a7 71 SUPERFAMILY SSF50182 20 70 4.85E-15 T 06-07-2017 IPR010920 LSM domain CAL12_RS17815 ff7c5da6197ea4ee1d1d6917c4a060a7 71 Pfam PF06004 Bacterial protein of unknown function (DUF903) 22 68 6.5E-22 T 06-07-2017 IPR010305 Protein of unknown function DUF903 CAL12_RS00625 ebcf214f3a55322fc1c0e96cbf656b23 273 Pfam PF00149 Calcineurin-like phosphoesterase 2 198 2.7E-16 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS00625 ebcf214f3a55322fc1c0e96cbf656b23 273 Gene3D G3DSA:3.60.21.10 3 246 1.1E-35 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS00625 ebcf214f3a55322fc1c0e96cbf656b23 273 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 255 39.101 T 06-07-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CAL12_RS00625 ebcf214f3a55322fc1c0e96cbf656b23 273 SUPERFAMILY SSF56300 1 254 2.43E-56 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 Pfam PF01895 PhoU domain 33 117 3.8E-19 T 06-07-2017 IPR026022 PhoU domain CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 Pfam PF01895 PhoU domain 135 220 3.0E-17 T 06-07-2017 IPR026022 PhoU domain CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 PIRSF PIRSF003107 13 234 7.9E-62 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 18 228 3.8E-65 T 06-07-2017 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 Gene3D G3DSA:1.20.58.220 134 242 2.2E-32 T 06-07-2017 CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 Gene3D G3DSA:1.20.58.220 15 127 2.9E-31 T 06-07-2017 CAL12_RS18025 3adb297a4b2e0f02545d4988b8828bf5 252 SUPERFAMILY SSF109755 18 237 3.66E-68 T 06-07-2017 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 SMART SM00825 Beta-ketoacyl synthase 19 398 2.0E-9 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 149 165 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 241 342 1.2E-23 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 SUPERFAMILY SSF53901 375 395 2.37E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 SUPERFAMILY SSF53901 70 101 2.37E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 SUPERFAMILY SSF53901 132 348 2.37E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 Gene3D G3DSA:3.40.47.10 68 230 1.4E-34 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 Gene3D G3DSA:3.40.47.10 245 396 5.8E-46 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10145 f01af5658583b91430d6139a529714ef 399 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 71 231 5.6E-25 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAL12_RS19800 083f45211b4052bfb191e1e31cb77a6f 470 PIRSF PIRSF002746 9 470 1.5E-133 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAL12_RS19800 083f45211b4052bfb191e1e31cb77a6f 470 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 14 469 3.5E-124 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAL12_RS19800 083f45211b4052bfb191e1e31cb77a6f 470 Pfam PF02447 GntP family permease 14 468 7.5E-132 T 06-07-2017 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-22 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 Gene3D G3DSA:1.10.10.10 1 87 3.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 SUPERFAMILY SSF53850 84 291 1.06E-37 T 06-07-2017 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 Gene3D G3DSA:3.40.190.10 89 184 3.8E-18 T 06-07-2017 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 Pfam PF03466 LysR substrate binding domain 87 290 1.2E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 SUPERFAMILY SSF46785 1 87 1.41E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15035 c2f4144628768ce44dfc0e976e8718b0 320 Gene3D G3DSA:3.40.190.10 185 247 1.8E-15 T 06-07-2017 CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 SMART SM00922 149 241 1.9E-15 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 36 129 1.5E-14 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 SUPERFAMILY SSF51604 117 361 1.15E-47 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 Gene3D G3DSA:3.20.20.120 134 360 5.7E-48 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 190 221 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 SUPERFAMILY SSF54826 5 133 2.09E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 Gene3D G3DSA:3.30.390.10 5 133 4.3E-38 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15265 e09bc0770c27eff13ee48e98bf68ba23 364 Pfam PF13378 Enolase C-terminal domain-like 157 356 1.8E-38 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Pfam PF00557 Metallopeptidase family M24 316 529 1.1E-44 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Pfam PF16189 Creatinase/Prolidase N-terminal domain 155 313 6.0E-37 T 06-07-2017 CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Pfam PF16188 C-terminal region of peptidase_M24 541 601 2.4E-22 T 06-07-2017 IPR032416 Peptidase M24, C-terminal domain CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 136 4.7E-15 T 06-07-2017 IPR000587 Creatinase, N-terminal GO:0016787 CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 SUPERFAMILY SSF55920 310 567 9.29E-54 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Gene3D G3DSA:3.40.350.10 5 136 7.5E-16 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Gene3D G3DSA:3.40.350.10 178 300 5.1E-10 T 06-07-2017 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 SUPERFAMILY SSF53092 169 299 7.32E-6 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 SUPERFAMILY SSF53092 6 137 1.1E-9 T 06-07-2017 IPR028980 Creatinase/Aminopeptidase P, N-terminal CAL12_RS08640 d96cc2ccf3333b7dde5b5f2779fbf02a 605 Gene3D G3DSA:3.90.230.10 308 568 5.2E-61 T 06-07-2017 IPR000994 Peptidase M24, structural domain CAL12_RS15720 ab7f3046fdb60315abc528039c4ae9fe 270 Gene3D G3DSA:3.40.1640.10 13 171 4.2E-65 T 06-07-2017 CAL12_RS15720 ab7f3046fdb60315abc528039c4ae9fe 270 Pfam PF07286 Protein of unknown function (DUF1445) 119 261 1.7E-69 T 06-07-2017 IPR009906 Protein of unknown function DUF1445 CAL12_RS15720 ab7f3046fdb60315abc528039c4ae9fe 270 PIRSF PIRSF029755 4 270 1.1E-125 T 06-07-2017 IPR016938 Uncharacterised protein family UPF0317 CAL12_RS15720 ab7f3046fdb60315abc528039c4ae9fe 270 Hamap MF_01830 UPF0317 protein . 15 269 55.654 T 06-07-2017 IPR016938 Uncharacterised protein family UPF0317 CAL12_RS15720 ab7f3046fdb60315abc528039c4ae9fe 270 SUPERFAMILY SSF160920 14 262 3.53E-115 T 06-07-2017 CAL12_RS25375 c6bdb81d6686fe0f1997630fe7141c58 522 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 522 210.571 T 06-07-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS25375 c6bdb81d6686fe0f1997630fe7141c58 522 Pfam PF04262 Glutamate-cysteine ligase 14 366 1.1E-155 T 06-07-2017 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS25375 c6bdb81d6686fe0f1997630fe7141c58 522 SUPERFAMILY SSF55931 13 511 1.9E-185 T 06-07-2017 CAL12_RS25375 c6bdb81d6686fe0f1997630fe7141c58 522 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 7 514 1.3E-190 T 06-07-2017 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 350 7.6E-147 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 Pfam PF13167 GTP-binding GTPase N-terminal 18 104 1.4E-29 T 06-07-2017 IPR025121 GTPase HflX, N-terminal CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 Pfam PF01926 50S ribosome-binding GTPase 192 310 8.0E-20 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 SUPERFAMILY SSF52540 190 350 1.03E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 3.6E-29 T 06-07-2017 IPR032305 GTP-binding protein, middle domain CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 Gene3D G3DSA:3.40.50.300 190 350 5.3E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 6.9E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 6.9E-7 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 PIRSF PIRSF006809 1 364 1.7E-134 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAL12_RS09255 705fb658a74384696e38e315aca9a358 368 Hamap MF_00900 GTPase HflX [hflX]. 19 355 44.593 T 06-07-2017 IPR016496 GTPase HflX GO:0005525 CAL12_RS01310 4ff936e9fa46903a0dd7f9ec64a044db 143 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 105 4.0E-13 T 06-07-2017 CAL12_RS01310 4ff936e9fa46903a0dd7f9ec64a044db 143 SUPERFAMILY SSF54593 5 126 1.06E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS01310 4ff936e9fa46903a0dd7f9ec64a044db 143 Gene3D G3DSA:3.10.180.10 4 119 3.1E-19 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS25970 84db4e33477b16b72db7122de93ee040 322 SUPERFAMILY SSF53850 115 281 4.8E-16 T 06-07-2017 CAL12_RS25970 84db4e33477b16b72db7122de93ee040 322 PIRSF PIRSF017082 2 321 5.0E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25970 84db4e33477b16b72db7122de93ee040 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 1.6E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 Gene3D G3DSA:3.20.20.140 59 364 4.0E-94 T 06-07-2017 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 Pfam PF01979 Amidohydrolase family 53 407 1.2E-43 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 SUPERFAMILY SSF51338 2 57 1.98E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 SUPERFAMILY SSF51338 366 407 1.98E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 SUPERFAMILY SSF51556 57 364 3.66E-88 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 Gene3D G3DSA:2.30.40.10 2 58 5.6E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS06885 9f747c062aff2b555d0b1c64c322edc0 410 Gene3D G3DSA:2.30.40.10 366 408 5.6E-23 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS15585 8aae0b2aa56166057712ab95b8270ba3 482 Gene3D G3DSA:3.40.50.10540 223 422 3.8E-70 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS15585 8aae0b2aa56166057712ab95b8270ba3 482 SUPERFAMILY SSF89796 48 222 5.76E-29 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS15585 8aae0b2aa56166057712ab95b8270ba3 482 Pfam PF02515 CoA-transferase family III 227 418 1.7E-45 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS15585 8aae0b2aa56166057712ab95b8270ba3 482 SUPERFAMILY SSF89796 225 423 5.49E-56 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS15585 8aae0b2aa56166057712ab95b8270ba3 482 Gene3D G3DSA:3.40.50.10540 51 156 1.9E-8 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01045 f8f2b8d1803283216c568793313eef33 232 Pfam PF05433 Glycine zipper 2TM domain 141 181 1.6E-9 T 06-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 CAL12_RS07015 42d9fec7c7d97fd4ae0c597a736aeb86 149 SMART SM00411 52 149 9.9E-11 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS07015 42d9fec7c7d97fd4ae0c597a736aeb86 149 Pfam PF00216 Bacterial DNA-binding protein 52 148 3.0E-15 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS07015 42d9fec7c7d97fd4ae0c597a736aeb86 149 SUPERFAMILY SSF47729 52 148 1.05E-12 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS07015 42d9fec7c7d97fd4ae0c597a736aeb86 149 Gene3D G3DSA:4.10.520.10 52 148 2.6E-13 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS08225 733820d9b768cad28dfc1dd843eb6c00 284 SUPERFAMILY SSF63380 5 107 1.0E-19 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS08225 733820d9b768cad28dfc1dd843eb6c00 284 Gene3D G3DSA:2.40.30.10 3 105 1.4E-24 T 06-07-2017 CAL12_RS08225 733820d9b768cad28dfc1dd843eb6c00 284 Pfam PF00175 Oxidoreductase NAD-binding domain 139 259 3.3E-9 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS08225 733820d9b768cad28dfc1dd843eb6c00 284 Gene3D G3DSA:3.40.50.80 130 284 1.2E-37 T 06-07-2017 CAL12_RS08225 733820d9b768cad28dfc1dd843eb6c00 284 SUPERFAMILY SSF52343 134 284 1.7E-28 T 06-07-2017 CAL12_RS24135 1606e20a90be43162870fc781fa27f2e 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 250 4.0E-52 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS24135 1606e20a90be43162870fc781fa27f2e 283 Gene3D G3DSA:3.40.190.10 17 151 1.9E-33 T 06-07-2017 CAL12_RS24135 1606e20a90be43162870fc781fa27f2e 283 SMART SM00062 31 252 6.6E-49 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS24135 1606e20a90be43162870fc781fa27f2e 283 SUPERFAMILY SSF53850 29 251 1.16E-56 T 06-07-2017 CAL12_RS24135 1606e20a90be43162870fc781fa27f2e 283 Gene3D G3DSA:3.40.190.10 156 252 2.4E-11 T 06-07-2017 CAL12_RS12080 4d88cbed99033cb9197784f1e695e1fd 332 Pfam PF05036 Sporulation related domain 255 329 1.7E-17 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS12080 4d88cbed99033cb9197784f1e695e1fd 332 SUPERFAMILY SSF110997 254 329 3.14E-15 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS12080 4d88cbed99033cb9197784f1e695e1fd 332 Gene3D G3DSA:3.30.70.1070 252 329 9.9E-16 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS23235 e77510c3a934d5011dc5398857a2e1b8 397 SUPERFAMILY SSF111369 64 301 1.12E-59 T 06-07-2017 CAL12_RS23235 e77510c3a934d5011dc5398857a2e1b8 397 Gene3D G3DSA:2.40.50.100 73 106 4.7E-21 T 06-07-2017 CAL12_RS23235 e77510c3a934d5011dc5398857a2e1b8 397 Gene3D G3DSA:2.40.50.100 181 215 4.7E-21 T 06-07-2017 CAL12_RS23235 e77510c3a934d5011dc5398857a2e1b8 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 63 296 1.1E-14 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS23235 e77510c3a934d5011dc5398857a2e1b8 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 48 373 1.8E-76 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS18350 9464a4511bdcd5d5f74845a603fa32cf 263 Gene3D G3DSA:3.40.50.1820 27 260 7.9E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS18350 9464a4511bdcd5d5f74845a603fa32cf 263 Pfam PF01738 Dienelactone hydrolase family 37 262 4.7E-62 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAL12_RS18350 9464a4511bdcd5d5f74845a603fa32cf 263 SUPERFAMILY SSF53474 26 263 2.92E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS20580 044d8ae43b939e259dc21eac7a2d4a42 141 Gene3D G3DSA:1.10.260.40 6 67 5.9E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS05655 036d88d91b25d104d8bebb0580c1c685 336 Pfam PF01699 Sodium/calcium exchanger protein 196 327 2.7E-10 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAL12_RS05655 036d88d91b25d104d8bebb0580c1c685 336 Pfam PF01699 Sodium/calcium exchanger protein 4 159 1.1E-15 T 06-07-2017 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 367 3.2E-187 T 06-07-2017 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|Reactome: R-HSA-71384 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 SUPERFAMILY SSF50129 318 368 8.95E-13 T 06-07-2017 IPR011032 GroES-like CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 Gene3D G3DSA:3.40.50.720 190 306 2.4E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 151 4.0E-24 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 SUPERFAMILY SSF50129 1 185 1.52E-70 T 06-07-2017 IPR011032 GroES-like CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 SMART SM00829 12 366 2.6E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 Pfam PF00107 Zinc-binding dehydrogenase 197 319 2.1E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 SUPERFAMILY SSF51735 160 333 4.06E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS00930 2acac772dd328603c5d3cb6c0f79a85c 368 Gene3D G3DSA:3.90.180.10 1 189 4.4E-64 T 06-07-2017 IPR011032 GroES-like CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 SUPERFAMILY SSF52540 7 257 1.74E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 Gene3D G3DSA:3.40.50.300 7 260 5.7E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 SMART SM00382 36 244 2.0E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 2.4E-20 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 321 7.1E-26 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15090 57befb28c483149b067f5c1790e692ce 330 Pfam PF00005 ABC transporter 28 186 5.1E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00795 1829fd4bc57b9b11df9db6ab43380f75 82 Pfam PF02416 mttA/Hcf106 family 5 50 1.8E-12 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAL12_RS00795 1829fd4bc57b9b11df9db6ab43380f75 82 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 46 1.3E-22 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAL12_RS00795 1829fd4bc57b9b11df9db6ab43380f75 82 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 75 22.447 T 06-07-2017 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 Pfam PF04055 Radical SAM superfamily 64 209 7.7E-14 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 SUPERFAMILY SSF102114 19 325 6.15E-88 T 06-07-2017 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 Gene3D G3DSA:3.20.20.70 20 325 2.1E-95 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 SMART SM00876 234 326 9.3E-43 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 SMART SM00729 57 269 6.5E-31 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 PIRSF PIRSF001619 6 332 1.3E-125 T 06-07-2017 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 TIGRFAM TIGR00433 bioB: biotin synthase 29 324 2.7E-119 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 Hamap MF_01694 Biotin synthase [bioB]. 19 327 40.905 T 06-07-2017 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAL12_RS04805 67f06a86834a424e0af75229b61701b9 333 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 234 324 4.4E-18 T 06-07-2017 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CAL12_RS18125 afe8e1dd6a4103af4c065c1c15954999 214 Gene3D G3DSA:2.30.110.10 1 197 1.0E-54 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS18125 afe8e1dd6a4103af4c065c1c15954999 214 Pfam PF01613 Flavin reductase like domain 22 163 2.3E-22 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS18125 afe8e1dd6a4103af4c065c1c15954999 214 SUPERFAMILY SSF50475 3 196 7.85E-44 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS18125 afe8e1dd6a4103af4c065c1c15954999 214 SMART SM00903 19 172 2.6E-26 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 SUPERFAMILY SSF52540 4 243 2.46E-88 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 SUPERFAMILY SSF50331 239 349 5.1E-11 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 Gene3D G3DSA:2.40.50.140 275 328 2.9E-5 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 SMART SM00382 29 212 1.8E-22 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 Gene3D G3DSA:3.40.50.300 3 235 8.8E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 Pfam PF08402 TOBE domain 273 347 2.1E-6 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS15135 da9110242ea578408b98fff345a9828b 352 Pfam PF00005 ABC transporter 20 162 9.1E-37 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 PRINTS PR00807 Pollen allergen Amb family signature 47 64 5.6E-12 T 06-07-2017 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 PRINTS PR00807 Pollen allergen Amb family signature 256 275 5.6E-12 T 06-07-2017 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 PRINTS PR00807 Pollen allergen Amb family signature 103 119 5.6E-12 T 06-07-2017 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 PRINTS PR00807 Pollen allergen Amb family signature 234 253 5.6E-12 T 06-07-2017 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 SUPERFAMILY SSF51126 334 385 5.13E-62 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 SUPERFAMILY SSF51126 47 284 5.13E-62 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 SMART SM00656 67 279 8.3E-21 T 06-07-2017 IPR002022 Pectate lyase/Amb allergen CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 Pfam PF00544 Pectate lyase 102 273 3.3E-22 T 06-07-2017 IPR002022 Pectate lyase/Amb allergen CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 Gene3D G3DSA:2.160.20.10 315 386 1.0E-80 T 06-07-2017 IPR012334 Pectin lyase fold CAL12_RS21915 215a67becab32c1f6093774b348e7ab6 403 Gene3D G3DSA:2.160.20.10 38 281 1.0E-80 T 06-07-2017 IPR012334 Pectin lyase fold CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 3.1E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 SMART SM00345 20 78 2.6E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 SMART SM00895 88 213 2.8E-10 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 Gene3D G3DSA:1.20.120.530 81 224 7.8E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 SUPERFAMILY SSF48008 84 222 1.2E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 SUPERFAMILY SSF46785 12 106 1.03E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 Pfam PF07729 FCD domain 89 210 1.8E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS16590 a7c4d09c887366722501771026f0d26d 226 Gene3D G3DSA:1.10.10.10 6 78 8.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16045 b67fc6f7371c5e41c6beb5d173376898 325 PIRSF PIRSF017082 1 324 1.8E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16045 b67fc6f7371c5e41c6beb5d173376898 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 5.5E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16045 b67fc6f7371c5e41c6beb5d173376898 325 SUPERFAMILY SSF53850 106 285 2.41E-13 T 06-07-2017 CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 Gene3D G3DSA:3.40.50.720 1 246 2.6E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 244 7.4E-60 T 06-07-2017 CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.8E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 SUPERFAMILY SSF51735 5 245 5.44E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09865 29e24446d79d2de2573e2fbe8bb73f6a 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 SUPERFAMILY SSF52922 714 901 8.24E-59 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 SUPERFAMILY SSF52518 64 476 2.07E-136 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 Gene3D G3DSA:3.40.50.970 483 714 1.3E-115 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 13 901 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 Gene3D G3DSA:3.40.50.920 718 900 1.4E-74 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 Gene3D G3DSA:3.40.50.970 64 478 5.2E-153 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 302 3.4E-9 T 06-07-2017 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 SUPERFAMILY SSF52518 483 711 4.83E-95 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS11740 ece33fd0834e7248131f7ba6b33b3c9c 902 PIRSF PIRSF000156 4 902 0.0 T 06-07-2017 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 263 271 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 SUPERFAMILY SSF55973 114 236 3.34E-52 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 SUPERFAMILY SSF55973 5 111 3.57E-45 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 387 56.618 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 SUPERFAMILY SSF55973 237 385 3.92E-67 T 06-07-2017 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Gene3D G3DSA:3.30.300.10 248 386 1.5E-68 T 06-07-2017 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Gene3D G3DSA:3.30.300.10 13 136 5.4E-46 T 06-07-2017 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 386 3.7E-182 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 235 3.4E-45 T 06-07-2017 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 4.1E-40 T 06-07-2017 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Gene3D G3DSA:3.30.300.10 137 237 8.1E-44 T 06-07-2017 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 PIRSF PIRSF000497 1 387 7.4E-170 T 06-07-2017 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 06-07-2017 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS26680 334435f5f2c4c2bf66344e65ddc28333 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 237 375 1.5E-67 T 06-07-2017 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 Pfam PF00672 HAMP domain 180 257 7.9E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 SMART SM00387 383 492 3.8E-22 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 490 2.2E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 SUPERFAMILY SSF47384 253 337 2.35E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 Gene3D G3DSA:1.10.287.130 262 333 1.3E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 337 1.8E-14 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 SMART SM00388 269 337 3.2E-17 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 434 1.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 1.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 1.1E-5 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 Gene3D G3DSA:3.30.565.10 342 490 4.9E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 SMART SM00304 199 261 5.6E-4 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS07935 a33648b21347f9a40dabbb9a11ce0ba8 500 SUPERFAMILY SSF55874 327 490 2.23E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11640 76f545c9b5e36bd87773d471422f3ecd 469 Gene3D G3DSA:3.30.1330.120 275 416 2.9E-16 T 06-07-2017 CAL12_RS11640 76f545c9b5e36bd87773d471422f3ecd 469 Pfam PF03972 MmgE/PrpD family 13 445 4.9E-111 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS11640 76f545c9b5e36bd87773d471422f3ecd 469 SUPERFAMILY SSF103378 11 455 1.7E-100 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS08190 3adb4daa289982264354dbe78e92be8a 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 282 6.8E-42 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 Gene3D G3DSA:3.40.190.10 91 176 9.2E-13 T 06-07-2017 CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 Pfam PF03466 LysR substrate binding domain 89 293 1.6E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 Gene3D G3DSA:1.10.10.10 3 88 2.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 Gene3D G3DSA:3.40.190.10 177 262 2.7E-15 T 06-07-2017 CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 9.4E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 SUPERFAMILY SSF46785 4 87 1.12E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05645 75c72d2437a0ecd54bbba84f5d647474 297 SUPERFAMILY SSF53850 91 293 3.65E-32 T 06-07-2017 CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 328 9.9E-25 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 SUPERFAMILY SSF52518 3 174 7.75E-46 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 173 2.9E-47 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 SUPERFAMILY SSF52518 365 571 2.32E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 SUPERFAMILY SSF52467 189 358 4.3E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 3.3E-26 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Gene3D G3DSA:3.40.50.1220 193 345 5.3E-41 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Gene3D G3DSA:3.40.50.970 346 554 1.8E-50 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 Gene3D G3DSA:3.40.50.970 2 177 3.5E-60 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS20060 2fe40fd742b8103ffb931967cef169bc 598 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 06-07-2017 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CAL12_RS20145 2b28d30159b8c7b6a415d0d831ced647 342 SUPERFAMILY SSF56349 56 337 3.53E-31 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAL12_RS20145 2b28d30159b8c7b6a415d0d831ced647 342 Gene3D G3DSA:1.10.443.10 177 338 9.6E-17 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS20145 2b28d30159b8c7b6a415d0d831ced647 342 Pfam PF00589 Phage integrase family 176 334 6.0E-13 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS16740 309008dbd7277e33238eda54652edf66 399 SUPERFAMILY SSF103473 16 391 8.24E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16740 309008dbd7277e33238eda54652edf66 399 Pfam PF07690 Major Facilitator Superfamily 23 236 7.4E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16740 309008dbd7277e33238eda54652edf66 399 Gene3D G3DSA:1.20.1250.20 19 203 6.6E-26 T 06-07-2017 CAL12_RS16740 309008dbd7277e33238eda54652edf66 399 Gene3D G3DSA:1.20.1250.20 212 390 9.1E-17 T 06-07-2017 CAL12_RS07970 5f36332ead1d6c55dd8c79e291207b68 384 Gene3D G3DSA:3.40.50.2000 168 345 3.0E-26 T 06-07-2017 CAL12_RS07970 5f36332ead1d6c55dd8c79e291207b68 384 Pfam PF00534 Glycosyl transferases group 1 194 350 5.5E-33 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS07970 5f36332ead1d6c55dd8c79e291207b68 384 Pfam PF13439 Glycosyltransferase Family 4 14 180 6.0E-17 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS07970 5f36332ead1d6c55dd8c79e291207b68 384 SUPERFAMILY SSF53756 4 369 5.89E-70 T 06-07-2017 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 1.5E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 1.5E-6 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Pfam PF02954 Bacterial regulatory protein, Fis family 399 439 7.6E-13 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 SMART SM00448 2 111 5.5E-31 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Pfam PF00072 Response regulator receiver domain 4 108 4.4E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 SUPERFAMILY SSF46689 348 439 3.84E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 SMART SM00382 156 300 1.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 06-07-2017 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Gene3D G3DSA:3.40.50.300 133 308 1.5E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 SUPERFAMILY SSF52172 1 181 2.13E-38 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 SUPERFAMILY SSF52540 136 376 2.38E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Gene3D G3DSA:1.10.10.60 394 438 6.7E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Gene3D G3DSA:3.40.50.2300 1 114 1.8E-29 T 06-07-2017 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Gene3D G3DSA:1.10.8.60 309 385 2.4E-19 T 06-07-2017 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 Pfam PF00158 Sigma-54 interaction domain 137 302 1.3E-67 T 06-07-2017 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CAL12_RS17635 776d73d400af9bb2eaa6096f25a8cd72 463 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 06-07-2017 IPR025944 Sigma-54 interaction domain, conserved site CAL12_RS17430 9f36a4d9dc3a3f2c7a1c68c3f5550e95 453 Pfam PF13742 OB-fold nucleic acid binding domain 18 109 8.9E-29 T 06-07-2017 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CAL12_RS17430 9f36a4d9dc3a3f2c7a1c68c3f5550e95 453 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 445 7.9E-137 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS17430 9f36a4d9dc3a3f2c7a1c68c3f5550e95 453 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 446 27.403 T 06-07-2017 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS17430 9f36a4d9dc3a3f2c7a1c68c3f5550e95 453 Pfam PF02601 Exonuclease VII, large subunit 133 443 1.9E-93 T 06-07-2017 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CAL12_RS08275 4a226ba5e8f08598c43462f1a91a036b 183 PIRSF PIRSF029681 2 183 1.2E-44 T 06-07-2017 IPR018550 Lipid A 3-O-deacylase-related CAL12_RS08275 4a226ba5e8f08598c43462f1a91a036b 183 SUPERFAMILY SSF56925 35 183 1.49E-6 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS08275 4a226ba5e8f08598c43462f1a91a036b 183 Gene3D G3DSA:2.40.160.20 36 183 9.4E-37 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS08275 4a226ba5e8f08598c43462f1a91a036b 183 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 88 181 2.9E-26 T 06-07-2017 IPR018550 Lipid A 3-O-deacylase-related CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 Gene3D G3DSA:1.10.10.10 145 220 5.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 SUPERFAMILY SSF52172 2 179 1.01E-43 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 219 7.1E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 Pfam PF00072 Response regulator receiver domain 2 110 1.9E-28 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 SMART SM00862 143 219 3.6E-22 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 SMART SM00448 1 110 3.8E-40 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS05415 3c97ed2193fbafa85193c9ef4cddc857 222 Gene3D G3DSA:3.40.50.2300 2 144 6.3E-43 T 06-07-2017 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 Pfam PF02040 Arsenical pump membrane protein 3 420 9.3E-148 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 2 424 3.0E-196 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 216 241 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 322 344 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 143 167 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 363 388 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 176 199 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 277 301 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS17620 3146397334470d8cb8ab57da006024d6 425 PRINTS PR00758 Arsenical pump membrane protein signature 396 420 1.1E-111 T 06-07-2017 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CAL12_RS07575 479756389dc731cb01c850db80abd803 265 Gene3D G3DSA:3.40.1280.10 13 172 3.0E-25 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS07575 479756389dc731cb01c850db80abd803 265 SUPERFAMILY SSF75217 11 176 3.53E-29 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS07575 479756389dc731cb01c850db80abd803 265 PIRSF PIRSF004808 10 265 1.0E-59 T 06-07-2017 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CAL12_RS07575 479756389dc731cb01c850db80abd803 265 Pfam PF00588 SpoU rRNA Methylase family 14 168 1.8E-33 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 358 8.2E-100 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 Gene3D G3DSA:3.40.140.10 5 134 2.4E-27 T 06-07-2017 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 105 5.9E-19 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 PIRSF PIRSF006769 1 365 6.0E-113 T 06-07-2017 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 SUPERFAMILY SSF53597 151 360 7.03E-56 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 SUPERFAMILY SSF53927 6 150 4.68E-44 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 152 361 4.1E-50 T 06-07-2017 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 Pfam PF01872 RibD C-terminal domain 153 336 5.7E-43 T 06-07-2017 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CAL12_RS24695 e64dbedfd28b00bed4984d68d5a8f529 377 Gene3D G3DSA:3.40.430.10 135 360 1.7E-68 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAL12_RS18675 c6878ef56522a51edb5f2b69b36acf48 254 PIRSF PIRSF037834 1 254 7.9E-101 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CAL12_RS18675 c6878ef56522a51edb5f2b69b36acf48 254 Gene3D G3DSA:1.20.1260.10 5 254 5.3E-99 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS18675 c6878ef56522a51edb5f2b69b36acf48 254 Pfam PF05138 Phenylacetic acid catabolic protein 4 254 1.9E-98 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAL12_RS18675 c6878ef56522a51edb5f2b69b36acf48 254 SUPERFAMILY SSF47240 4 248 1.3E-84 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS18675 c6878ef56522a51edb5f2b69b36acf48 254 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 254 2.2E-86 T 06-07-2017 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 Pfam PF03466 LysR substrate binding domain 90 289 1.1E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 SUPERFAMILY SSF46785 1 110 2.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.6E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 SUPERFAMILY SSF53850 91 293 1.28E-25 T 06-07-2017 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 Gene3D G3DSA:3.40.190.10 186 251 1.3E-7 T 06-07-2017 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 Gene3D G3DSA:1.10.10.10 1 84 1.6E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19730 df5df1c66a0b5dd78640e2a54e7ef068 323 Gene3D G3DSA:3.40.190.10 92 185 1.4E-15 T 06-07-2017 CAL12_RS18405 fa94186fcb2d06b2f91635b82b1ab90a 199 Pfam PF00881 Nitroreductase family 10 177 1.9E-14 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAL12_RS18405 fa94186fcb2d06b2f91635b82b1ab90a 199 Gene3D G3DSA:3.40.109.10 5 198 2.8E-69 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS18405 fa94186fcb2d06b2f91635b82b1ab90a 199 SUPERFAMILY SSF55469 4 198 6.67E-70 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS12880 967f9c9a0129216f9bb7f98303a40101 344 SUPERFAMILY SSF53850 36 264 3.48E-36 T 06-07-2017 CAL12_RS12880 967f9c9a0129216f9bb7f98303a40101 344 Gene3D G3DSA:3.40.190.10 120 214 6.5E-14 T 06-07-2017 CAL12_RS12880 967f9c9a0129216f9bb7f98303a40101 344 Pfam PF09084 NMT1/THI5 like 48 253 2.8E-38 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 335 1.1E-113 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 Pfam PF02504 Fatty acid synthesis protein 2 323 1.8E-106 T 06-07-2017 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 PIRSF PIRSF002465 1 337 5.2E-130 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 Gene3D G3DSA:3.40.718.10 2 333 9.0E-135 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 339 153.229 T 06-07-2017 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 CAL12_RS08350 ea9cd06b3b8b02f404411a1e963cbad5 359 SUPERFAMILY SSF53659 2 333 2.88E-105 T 06-07-2017 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 SUPERFAMILY SSF46689 265 315 3.0E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 Gene3D G3DSA:1.10.10.60 209 266 1.2E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 Pfam PF06719 AraC-type transcriptional regulator N-terminus 49 200 4.3E-45 T 06-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 SUPERFAMILY SSF46689 212 263 7.37E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 SMART SM00342 229 312 9.6E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 Pfam PF12833 Helix-turn-helix domain 235 310 4.6E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 Gene3D G3DSA:1.10.10.60 267 314 1.7E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21310 d6c8f9e768b478b68a71e5087992edce 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS16485 abf48f6290abc84b67365d64eec13c53 205 SUPERFAMILY SSF48498 84 199 1.14E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16485 abf48f6290abc84b67365d64eec13c53 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.2E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16485 abf48f6290abc84b67365d64eec13c53 205 Gene3D G3DSA:1.10.357.10 72 200 4.6E-34 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16485 abf48f6290abc84b67365d64eec13c53 205 Gene3D G3DSA:1.10.10.60 3 71 3.0E-22 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16485 abf48f6290abc84b67365d64eec13c53 205 SUPERFAMILY SSF46689 3 88 1.69E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS14970 fbced334426721365719332dc3cc0a5c 111 SUPERFAMILY SSF52091 1 108 6.47E-27 T 06-07-2017 IPR002645 STAS domain CAL12_RS14970 fbced334426721365719332dc3cc0a5c 111 Pfam PF01740 STAS domain 5 105 2.7E-19 T 06-07-2017 IPR002645 STAS domain CAL12_RS14970 fbced334426721365719332dc3cc0a5c 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 102 3.3E-24 T 06-07-2017 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CAL12_RS14970 fbced334426721365719332dc3cc0a5c 111 Gene3D G3DSA:3.30.750.24 1 108 2.7E-28 T 06-07-2017 IPR002645 STAS domain CAL12_RS13005 141debec1f89a7e8666a5b25467ccc31 252 Gene3D G3DSA:3.40.50.720 1 200 8.1E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13005 141debec1f89a7e8666a5b25467ccc31 252 Pfam PF13460 NAD(P)H-binding 7 133 3.8E-11 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13005 141debec1f89a7e8666a5b25467ccc31 252 SUPERFAMILY SSF51735 1 202 2.01E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26690 93f58eb677fd6f3a163bf524e350411f 296 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 23 287 4.4E-60 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAL12_RS26690 93f58eb677fd6f3a163bf524e350411f 296 PIRSF PIRSF026649 1 296 9.2E-75 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAL12_RS08725 5d26bbe4f02f05399ececd6407a76d99 233 Pfam PF04390 Lipopolysaccharide-assembly 27 175 1.3E-16 T 06-07-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CAL12_RS08725 5d26bbe4f02f05399ececd6407a76d99 233 Gene3D G3DSA:3.30.160.150 36 181 1.4E-42 T 06-07-2017 CAL12_RS08725 5d26bbe4f02f05399ececd6407a76d99 233 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 21 180 24.056 T 06-07-2017 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 Pfam PF01565 FAD binding domain 54 183 3.7E-27 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 Gene3D G3DSA:3.30.43.10 4 104 8.2E-21 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 SUPERFAMILY SSF55103 291 446 8.01E-6 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 SUPERFAMILY SSF55103 201 235 8.01E-6 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 Gene3D G3DSA:3.30.465.10 114 219 7.3E-6 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS24485 d9f43d6ad6637ad5bd471821d8da903e 462 SUPERFAMILY SSF56176 5 221 4.67E-38 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 5.3E-38 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 SUPERFAMILY SSF55424 346 458 2.92E-22 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 6.1E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 4.8E-13 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 4.8E-13 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 4.8E-13 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 4.8E-13 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 SUPERFAMILY SSF51905 1 56 1.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 SUPERFAMILY SSF51905 94 191 1.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 SUPERFAMILY SSF51905 219 362 1.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 453 1.0E-14 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Gene3D G3DSA:3.30.390.30 349 458 5.9E-21 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 PIRSF PIRSF000350 1 464 4.1E-52 T 06-07-2017 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Gene3D G3DSA:3.50.50.60 149 257 1.6E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Gene3D G3DSA:3.50.50.60 258 337 4.8E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11695 a106181a1bd3f86d74fcabf47a11bcd9 472 Gene3D G3DSA:3.50.50.60 5 148 6.5E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26900 2d38082dd9fb9ac622b5ee24bc05193b 279 Pfam PF01061 ABC-2 type transporter 24 236 5.3E-26 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAL12_RS26900 2d38082dd9fb9ac622b5ee24bc05193b 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 160 184 4.8E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS26900 2d38082dd9fb9ac622b5ee24bc05193b 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 44 65 4.8E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS26900 2d38082dd9fb9ac622b5ee24bc05193b 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 4.8E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS09950 74e67ab2ecf0e6dff542d21bed43c91c 149 SMART SM00422 19 89 1.1E-9 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS09950 74e67ab2ecf0e6dff542d21bed43c91c 149 SUPERFAMILY SSF46955 17 119 1.33E-19 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS09950 74e67ab2ecf0e6dff542d21bed43c91c 149 Pfam PF13411 MerR HTH family regulatory protein 19 85 2.2E-22 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS09950 74e67ab2ecf0e6dff542d21bed43c91c 149 Gene3D G3DSA:1.10.1660.10 19 133 2.2E-18 T 06-07-2017 CAL12_RS18230 6bd65509ab506dd288c7863cf0b00860 395 Gene3D G3DSA:3.40.640.10 45 257 4.1E-61 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS18230 6bd65509ab506dd288c7863cf0b00860 395 Pfam PF00155 Aminotransferase class I and II 31 375 2.8E-54 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS18230 6bd65509ab506dd288c7863cf0b00860 395 Gene3D G3DSA:3.90.1150.10 258 390 3.2E-43 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18230 6bd65509ab506dd288c7863cf0b00860 395 SUPERFAMILY SSF53383 1 389 2.55E-106 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS00425 8e766a9efbc204674b541390b1747cb8 175 SUPERFAMILY SSF52309 6 161 3.66E-43 T 06-07-2017 CAL12_RS00425 8e766a9efbc204674b541390b1747cb8 175 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 7 145 5.4E-44 T 06-07-2017 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 CAL12_RS00425 8e766a9efbc204674b541390b1747cb8 175 Gene3D G3DSA:3.40.50.1810 6 150 2.0E-22 T 06-07-2017 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 CAL12_RS12775 b774ca5c237feb3e39b3a9862616f54d 329 PIRSF PIRSF017082 1 325 1.4E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12775 b774ca5c237feb3e39b3a9862616f54d 329 SUPERFAMILY SSF53850 93 280 5.82E-11 T 06-07-2017 CAL12_RS12775 b774ca5c237feb3e39b3a9862616f54d 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 321 8.0E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 Pfam PF00990 Diguanylate cyclase, GGDEF domain 362 510 7.5E-40 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 Gene3D G3DSA:3.30.70.270 363 517 7.5E-50 T 06-07-2017 CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 358 514 2.7E-45 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 SMART SM00267 350 515 9.3E-55 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 SUPERFAMILY SSF103190 62 172 8.24E-9 T 06-07-2017 IPR029151 Periplasmic sensor domain-like CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 Gene3D G3DSA:3.30.450.20 142 279 2.7E-15 T 06-07-2017 CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 Pfam PF02743 Cache domain 49 263 1.2E-22 T 06-07-2017 IPR033479 Double Cache domain 1 CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 SUPERFAMILY SSF103190 184 262 3.45E-9 T 06-07-2017 IPR029151 Periplasmic sensor domain-like CAL12_RS21990 a09d21ba1adabaee90b67331a23cf13b 531 SUPERFAMILY SSF55073 366 514 2.43E-45 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 Gene3D G3DSA:3.30.70.260 145 201 1.6E-26 T 06-07-2017 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 219 1.1E-59 T 06-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 SUPERFAMILY SSF100950 4 151 3.56E-40 T 06-07-2017 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 218 1.7E-56 T 06-07-2017 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 SUPERFAMILY SSF75445 132 203 9.03E-22 T 06-07-2017 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 222 33.081 T 06-07-2017 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CAL12_RS18030 5e3dd1b5e53733610890208b9c2b1438 225 Gene3D G3DSA:3.40.50.1360 6 144 5.4E-52 T 06-07-2017 CAL12_RS22805 82e0d956ebe5bf60ddd7236cca61e440 265 Gene3D G3DSA:3.90.850.10 9 262 1.0E-38 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS22805 82e0d956ebe5bf60ddd7236cca61e440 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 102 236 5.5E-8 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS22805 82e0d956ebe5bf60ddd7236cca61e440 265 SUPERFAMILY SSF56529 7 245 2.22E-36 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS18620 8993ff7bce3f9e4e529a934a8f7b163f 158 SUPERFAMILY SSF54534 13 157 2.55E-27 T 06-07-2017 CAL12_RS18620 8993ff7bce3f9e4e529a934a8f7b163f 158 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 13 86 4.3E-9 T 06-07-2017 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 CAL12_RS18620 8993ff7bce3f9e4e529a934a8f7b163f 158 Gene3D G3DSA:3.10.50.40 144 157 8.8E-14 T 06-07-2017 CAL12_RS18620 8993ff7bce3f9e4e529a934a8f7b163f 158 Gene3D G3DSA:3.10.50.40 11 93 8.8E-14 T 06-07-2017 CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 Gene3D G3DSA:1.20.1050.10 93 190 1.7E-21 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 Gene3D G3DSA:3.40.30.10 1 92 8.7E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 83 1.6E-7 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 SUPERFAMILY SSF47616 84 200 4.32E-19 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 SUPERFAMILY SSF52833 1 88 7.01E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14090 7c547b3d20b4cbf5d94d5ec51a1b89e6 214 Pfam PF14497 Glutathione S-transferase, C-terminal domain 122 199 6.3E-6 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 SUPERFAMILY SSF53335 74 262 1.79E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 Pfam PF01739 CheR methyltransferase, SAM binding domain 74 256 6.5E-52 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 Gene3D G3DSA:1.10.155.10 3 72 1.2E-21 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 133 149 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 67 79 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 100 120 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 7.2E-42 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 PIRSF PIRSF000410 1 264 1.1E-90 T 06-07-2017 IPR026024 Chemotaxis protein methyltransferase CheR CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 SMART SM00138 6 264 2.9E-88 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 Gene3D G3DSA:3.40.50.150 73 262 1.7E-63 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 SUPERFAMILY SSF47757 3 73 3.66E-17 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS23720 da6d9ca696dbe9773a074f639a904b18 264 Pfam PF03705 CheR methyltransferase, all-alpha domain 8 56 2.4E-15 T 06-07-2017 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 Gene3D G3DSA:3.40.190.10 164 282 2.1E-37 T 06-07-2017 CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 Gene3D G3DSA:3.10.105.10 283 477 1.7E-44 T 06-07-2017 CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 Gene3D G3DSA:3.90.76.10 16 163 1.2E-36 T 06-07-2017 CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 50 419 1.4E-78 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 PIRSF PIRSF002741 2 506 1.1E-89 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS24540 1fc6c965a60dbfd9dc27ef8fb4d2df16 508 SUPERFAMILY SSF53850 7 488 1.99E-120 T 06-07-2017 CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 Gene3D G3DSA:3.40.50.720 11 256 1.1E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.0E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.2E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 SUPERFAMILY SSF51735 11 256 2.87E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05805 61ead8a6cd3910baef557bebca7664a6 285 Pfam PF00106 short chain dehydrogenase 12 194 9.7E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 730 917 1.5E-18 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 Gene3D G3DSA:3.40.920.10 723 922 5.3E-16 T 06-07-2017 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 Gene3D G3DSA:3.40.50.970 487 644 5.3E-7 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 SUPERFAMILY SSF52518 435 616 1.77E-11 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 SUPERFAMILY SSF53323 722 923 1.31E-25 T 06-07-2017 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 SUPERFAMILY SSF52518 26 209 4.53E-13 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS19955 4f5638c8506fe1218def912f9f4c557b 1183 SUPERFAMILY SSF52922 273 350 5.83E-7 T 06-07-2017 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CAL12_RS14415 19a0fc737fb219fcf33173d44b9fe663 330 PIRSF PIRSF017082 1 330 8.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14415 19a0fc737fb219fcf33173d44b9fe663 330 SUPERFAMILY SSF53850 117 290 7.24E-11 T 06-07-2017 CAL12_RS14415 19a0fc737fb219fcf33173d44b9fe663 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 326 4.3E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25580 9201a0faa3253d9711770107607aba89 518 Pfam PF03109 ABC1 family 109 230 4.8E-32 T 06-07-2017 IPR004147 UbiB domain CAL12_RS25580 9201a0faa3253d9711770107607aba89 518 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 443 3.3E-172 T 06-07-2017 IPR010232 Probable protein kinase UbiB GO:0006744 CAL12_RS25580 9201a0faa3253d9711770107607aba89 518 SUPERFAMILY SSF56112 189 436 1.58E-43 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS25580 9201a0faa3253d9711770107607aba89 518 SUPERFAMILY SSF56112 91 154 1.58E-43 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS25580 9201a0faa3253d9711770107607aba89 518 Gene3D G3DSA:3.90.1200.10 260 315 1.6E-4 T 06-07-2017 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 1 543 4.6E-148 T 06-07-2017 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 248 538 1.0E-103 T 06-07-2017 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 SUPERFAMILY SSF52009 119 243 1.07E-32 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Gene3D G3DSA:1.10.274.10 19 126 6.8E-33 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 SUPERFAMILY SSF51621 247 542 1.75E-97 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 444 459 1.7E-21 T 06-07-2017 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 497 509 1.7E-21 T 06-07-2017 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 290 309 1.7E-21 T 06-07-2017 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 461 476 1.7E-21 T 06-07-2017 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Gene3D G3DSA:3.50.30.10 127 253 2.6E-41 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 PIRSF PIRSF000732 1 561 2.2E-196 T 06-07-2017 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 444 462 - T 06-07-2017 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Gene3D G3DSA:3.20.20.60 254 552 1.5E-96 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Pfam PF05524 PEP-utilising enzyme, N-terminal 1 120 2.8E-23 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 SUPERFAMILY SSF47831 19 137 1.83E-28 T 06-07-2017 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 Pfam PF00391 PEP-utilising enzyme, mobile domain 149 222 4.4E-22 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS09775 360b447aa61506fcf6a208b202d61fcf 564 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 181 192 - T 06-07-2017 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CAL12_RS23210 c3b43e3da000d217d4565960eb5db0de 399 Gene3D G3DSA:3.40.50.2300 162 306 4.7E-21 T 06-07-2017 CAL12_RS23210 c3b43e3da000d217d4565960eb5db0de 399 Gene3D G3DSA:3.40.50.2300 26 152 1.7E-35 T 06-07-2017 CAL12_RS23210 c3b43e3da000d217d4565960eb5db0de 399 Gene3D G3DSA:3.40.50.2300 307 360 1.7E-35 T 06-07-2017 CAL12_RS23210 c3b43e3da000d217d4565960eb5db0de 399 Pfam PF13458 Periplasmic binding protein 32 368 1.3E-73 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS23210 c3b43e3da000d217d4565960eb5db0de 399 SUPERFAMILY SSF53822 32 398 2.88E-80 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 SUPERFAMILY SSF53850 25 249 1.03E-64 T 06-07-2017 CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 PIRSF PIRSF004846 1 251 2.9E-54 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 Pfam PF13531 Bacterial extracellular solute-binding protein 27 249 1.4E-47 T 06-07-2017 CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 Gene3D G3DSA:3.40.190.10 131 212 6.9E-23 T 06-07-2017 CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 Gene3D G3DSA:3.40.190.10 25 130 1.0E-35 T 06-07-2017 CAL12_RS12640 ff6c5fcd2271cb594afd1dd213660d8e 251 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 248 1.6E-77 T 06-07-2017 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 CAL12_RS23135 0a1991186db5c0db1ae4af79fb96396b 272 SMART SM00382 47 228 1.8E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23135 0a1991186db5c0db1ae4af79fb96396b 272 Gene3D G3DSA:3.40.50.300 19 224 1.8E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23135 0a1991186db5c0db1ae4af79fb96396b 272 SUPERFAMILY SSF52540 19 234 3.34E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23135 0a1991186db5c0db1ae4af79fb96396b 272 Pfam PF00005 ABC transporter 38 177 4.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS21855 54e86b1616ef25b2e0f95e516f02e91d 178 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 110 1.1E-7 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS21855 54e86b1616ef25b2e0f95e516f02e91d 178 Gene3D G3DSA:1.20.1290.10 139 176 9.4E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS21855 54e86b1616ef25b2e0f95e516f02e91d 178 Gene3D G3DSA:1.20.1290.10 1 89 9.4E-29 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS21855 54e86b1616ef25b2e0f95e516f02e91d 178 SUPERFAMILY SSF69118 1 176 6.41E-43 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS21855 54e86b1616ef25b2e0f95e516f02e91d 178 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 102 4.1E-10 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS01150 6c91b0a10a4434789add311b0ad9961b 438 SUPERFAMILY SSF103473 9 437 1.96E-76 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01150 6c91b0a10a4434789add311b0ad9961b 438 Gene3D G3DSA:1.20.1250.20 24 203 1.7E-30 T 06-07-2017 CAL12_RS01150 6c91b0a10a4434789add311b0ad9961b 438 Gene3D G3DSA:1.20.1250.20 254 435 1.5E-21 T 06-07-2017 CAL12_RS01150 6c91b0a10a4434789add311b0ad9961b 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 310 325 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS01150 6c91b0a10a4434789add311b0ad9961b 438 Pfam PF07690 Major Facilitator Superfamily 33 396 1.6E-43 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:3.30.2090.10 724 811 1.0E-26 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82693 566 671 2.09E-29 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82693 38 131 5.06E-27 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:1.10.3850.10 281 498 2.0E-60 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:1.10.3850.10 816 1029 3.2E-57 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:3.30.2090.10 181 275 1.6E-23 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82714 724 811 1.57E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.5E-111 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:3.30.70.1430 38 139 4.7E-34 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82714 182 272 7.46E-21 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82866 296 497 1.28E-49 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82693 135 182 1.57E-26 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82693 274 330 1.57E-26 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Gene3D G3DSA:3.30.70.1430 568 671 7.3E-36 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1038 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 SUPERFAMILY SSF82866 807 1030 3.79E-46 T 06-07-2017 CAL12_RS15775 fdf4db92a8eb8f3e9741b8f2bf317027 1063 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS26760 f3db87f719d21c3b4e0680acd7774be0 196 SUPERFAMILY SSF47240 74 184 1.8E-5 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS26760 f3db87f719d21c3b4e0680acd7774be0 196 Gene3D G3DSA:1.20.1260.10 40 180 1.6E-12 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS26760 f3db87f719d21c3b4e0680acd7774be0 196 Pfam PF13628 Domain of unknown function (DUF4142) 48 184 2.1E-48 T 06-07-2017 IPR025419 Domain of unknown function DUF4142 CAL12_RS10165 06c2c11902d68c82b17562cf385e51ba 205 Gene3D G3DSA:2.50.20.10 30 198 1.0E-13 T 06-07-2017 CAL12_RS10165 06c2c11902d68c82b17562cf385e51ba 205 SUPERFAMILY SSF89392 29 198 4.32E-12 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAL12_RS10165 06c2c11902d68c82b17562cf385e51ba 205 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 42 198 6.3E-9 T 06-07-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CAL12_RS14075 2244ee7cc80e94bde41171eebc74547a 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 6.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14075 2244ee7cc80e94bde41171eebc74547a 325 PIRSF PIRSF017082 2 325 3.2E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14075 2244ee7cc80e94bde41171eebc74547a 325 Gene3D G3DSA:3.40.190.10 129 245 1.0E-6 T 06-07-2017 CAL12_RS14075 2244ee7cc80e94bde41171eebc74547a 325 SUPERFAMILY SSF53850 100 278 1.36E-18 T 06-07-2017 CAL12_RS21540 44261d2118737c57399d455bcee91dcb 215 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 17 215 29.592 T 06-07-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CAL12_RS21540 44261d2118737c57399d455bcee91dcb 215 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 17 212 3.3E-18 T 06-07-2017 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 CAL12_RS21540 44261d2118737c57399d455bcee91dcb 215 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 42 205 7.2E-46 T 06-07-2017 IPR004564 Outer membrane lipoprotein carrier protein LolA-like CAL12_RS21540 44261d2118737c57399d455bcee91dcb 215 Gene3D G3DSA:2.50.20.10 32 214 1.7E-60 T 06-07-2017 CAL12_RS21540 44261d2118737c57399d455bcee91dcb 215 SUPERFAMILY SSF89392 33 214 6.28E-46 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAL12_RS27345 fa24637bd7c48c89ed67c0f2200e2506 249 Pfam PF01203 Type II secretion system (T2SS), protein N 39 237 7.1E-19 T 06-07-2017 IPR022792 Type II secretion system, protein N CAL12_RS05420 a2b608802e0edf7de28ab067c1636e17 287 Gene3D G3DSA:3.40.50.720 18 284 1.8E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05420 a2b608802e0edf7de28ab067c1636e17 287 Pfam PF00899 ThiF family 30 280 7.6E-35 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAL12_RS05420 a2b608802e0edf7de28ab067c1636e17 287 SUPERFAMILY SSF69572 17 206 3.4E-53 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAL12_RS05420 a2b608802e0edf7de28ab067c1636e17 287 SUPERFAMILY SSF69572 237 284 3.4E-53 T 06-07-2017 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CAL12_RS26355 389437660f9e1a6f3722f49c2ea197a9 194 Gene3D G3DSA:3.40.50.450 2 187 6.5E-71 T 06-07-2017 CAL12_RS26355 389437660f9e1a6f3722f49c2ea197a9 194 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 181 1.1E-61 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAL12_RS26355 389437660f9e1a6f3722f49c2ea197a9 194 SUPERFAMILY SSF102405 4 181 3.51E-61 T 06-07-2017 CAL12_RS26355 389437660f9e1a6f3722f49c2ea197a9 194 Pfam PF03641 Possible lysine decarboxylase 48 177 3.1E-41 T 06-07-2017 IPR031100 LOG family CAL12_RS26170 0b039aa545227bac2a8fd5c3c2154f4c 191 SUPERFAMILY SSF48498 81 181 4.75E-10 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS26170 0b039aa545227bac2a8fd5c3c2154f4c 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 56 1.3E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS26170 0b039aa545227bac2a8fd5c3c2154f4c 191 SUPERFAMILY SSF46689 3 72 1.42E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26170 0b039aa545227bac2a8fd5c3c2154f4c 191 Gene3D G3DSA:1.10.357.10 3 190 5.2E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS06860 3fb1be106aed809c37a680330df8a51a 290 Gene3D G3DSA:1.10.3470.10 54 255 1.9E-5 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS06860 3fb1be106aed809c37a680330df8a51a 290 SUPERFAMILY SSF81345 50 273 3.01E-6 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS06860 3fb1be106aed809c37a680330df8a51a 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 275 8.9E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 348 - T 06-07-2017 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 17 410 1.6E-143 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Pfam PF00171 Aldehyde dehydrogenase family 312 378 1.6E-7 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Pfam PF00171 Aldehyde dehydrogenase family 14 285 1.2E-21 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 SUPERFAMILY SSF53720 10 420 1.83E-122 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 PIRSF PIRSF000151 2 421 4.5E-171 T 06-07-2017 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 9 420 41.458 T 06-07-2017 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Gene3D G3DSA:3.40.605.10 4 228 3.4E-103 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Gene3D G3DSA:3.40.605.10 379 420 3.4E-103 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08715 9ec184ddee54a8527e1302b3d9162df1 421 Gene3D G3DSA:3.40.309.10 230 378 6.5E-44 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 SUPERFAMILY SSF53335 17 221 6.05E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 PIRSF PIRSF003078 11 223 2.3E-50 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 Pfam PF02527 rRNA small subunit methyltransferase G 34 210 2.9E-46 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 37 219 4.4E-44 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 24 218 25.887 T 06-07-2017 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CAL12_RS27850 8b5ce278099850ac3c31516167f42781 230 Gene3D G3DSA:3.40.50.150 14 222 9.9E-62 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 Pfam PF08402 TOBE domain 281 359 5.8E-9 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 SUPERFAMILY SSF52540 6 244 7.64E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 Pfam PF00005 ABC transporter 21 163 2.8E-36 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 SUPERFAMILY SSF50331 239 358 4.02E-12 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 SMART SM00382 30 213 2.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04055 8f5b253fefa47ce48b228e846dd5329d 361 Gene3D G3DSA:3.40.50.300 2 235 8.8E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 688 696 - T 06-07-2017 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 SUPERFAMILY SSF52540 317 598 1.73E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 TIGRFAM TIGR00763 lon: endopeptidase La 15 783 1.6E-299 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PIRSF PIRSF001174 3 787 0.0 T 06-07-2017 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 9.1E-18 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 SUPERFAMILY SSF88697 13 204 2.49E-51 T 06-07-2017 IPR015947 PUA-like domain CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 203 1.6E-40 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 SMART SM00382 350 494 5.2E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Gene3D G3DSA:3.40.50.300 317 501 1.1E-33 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Gene3D G3DSA:3.30.230.10 601 783 5.0E-75 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 SMART SM00464 13 205 1.1E-71 T 06-07-2017 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Hamap MF_01973 Lon protease [lon]. 14 784 70.695 T 06-07-2017 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 685 704 3.4E-55 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 738 756 3.4E-55 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 623 3.4E-55 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 715 734 3.4E-55 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 3.4E-55 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 582 784 1.2E-95 T 06-07-2017 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 Gene3D G3DSA:1.10.8.60 502 596 4.1E-32 T 06-07-2017 CAL12_RS17205 b4b5d841d57239507c9a8f94ef8ae7d5 817 SUPERFAMILY SSF54211 607 782 1.71E-56 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS25915 9e7e9256b4db408c0b4f7d06350d4f25 683 SUPERFAMILY SSF53067 398 480 1.37E-8 T 06-07-2017 CAL12_RS25915 9e7e9256b4db408c0b4f7d06350d4f25 683 SUPERFAMILY SSF53067 261 344 1.37E-8 T 06-07-2017 CAL12_RS25915 9e7e9256b4db408c0b4f7d06350d4f25 683 SUPERFAMILY SSF53067 4 79 1.37E-8 T 06-07-2017 CAL12_RS25915 9e7e9256b4db408c0b4f7d06350d4f25 683 Pfam PF01968 Hydantoinase/oxoprolinase 203 489 4.3E-100 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS25915 9e7e9256b4db408c0b4f7d06350d4f25 683 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 182 6.1E-52 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS00545 5297a271133ef25520a84a48259a74f7 127 Gene3D G3DSA:1.10.1660.10 6 58 5.8E-20 T 06-07-2017 CAL12_RS00545 5297a271133ef25520a84a48259a74f7 127 Gene3D G3DSA:1.10.1660.10 59 121 3.2E-13 T 06-07-2017 CAL12_RS00545 5297a271133ef25520a84a48259a74f7 127 Pfam PF13411 MerR HTH family regulatory protein 7 71 2.2E-15 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS00545 5297a271133ef25520a84a48259a74f7 127 SMART SM00422 6 73 7.2E-19 T 06-07-2017 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CAL12_RS00545 5297a271133ef25520a84a48259a74f7 127 SUPERFAMILY SSF46955 6 120 1.47E-24 T 06-07-2017 IPR009061 Putative DNA-binding domain CAL12_RS26580 366e253bb42b6681756676ac697f87bd 207 SUPERFAMILY SSF100950 13 203 8.51E-42 T 06-07-2017 CAL12_RS26580 366e253bb42b6681756676ac697f87bd 207 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 13 199 3.4E-36 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAL12_RS26580 366e253bb42b6681756676ac697f87bd 207 Gene3D G3DSA:3.40.50.10420 13 203 8.8E-45 T 06-07-2017 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain CAL12_RS26580 366e253bb42b6681756676ac697f87bd 207 PIRSF PIRSF006806 6 202 8.4E-27 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAL12_RS26580 366e253bb42b6681756676ac697f87bd 207 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 13 199 2.1E-27 T 06-07-2017 IPR002698 5-formyltetrahydrofolate cyclo-ligase CAL12_RS07910 0ded5a08c47375a93a71312a5695428a 264 SMART SM00849 36 236 2.4E-9 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07910 0ded5a08c47375a93a71312a5695428a 264 Gene3D G3DSA:3.60.15.10 28 239 5.2E-31 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07910 0ded5a08c47375a93a71312a5695428a 264 SUPERFAMILY SSF56281 27 240 3.36E-32 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07910 0ded5a08c47375a93a71312a5695428a 264 Pfam PF00753 Metallo-beta-lactamase superfamily 38 236 7.3E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS19900 c9f530b9ef2621ce31d281926b0eba36 292 Pfam PF05067 Manganese containing catalase 1 288 8.0E-87 T 06-07-2017 IPR007760 Manganese catalase CAL12_RS19900 c9f530b9ef2621ce31d281926b0eba36 292 SUPERFAMILY SSF47240 1 287 7.3E-85 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS19900 c9f530b9ef2621ce31d281926b0eba36 292 Gene3D G3DSA:1.20.1260.10 1 199 4.1E-75 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS20350 f493eda0ca38b22cc85a2707c107245f 293 SUPERFAMILY SSF53335 66 224 5.84E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20350 f493eda0ca38b22cc85a2707c107245f 293 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 121 137 6.5E-7 T 06-07-2017 CAL12_RS20350 f493eda0ca38b22cc85a2707c107245f 293 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 156 170 6.5E-7 T 06-07-2017 CAL12_RS20350 f493eda0ca38b22cc85a2707c107245f 293 Gene3D G3DSA:3.40.50.150 118 224 2.9E-13 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20350 f493eda0ca38b22cc85a2707c107245f 293 Pfam PF02384 N-6 DNA Methylase 117 223 2.0E-7 T 06-07-2017 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CAL12_RS20090 85e6585c38106756d3b5616e6d99932e 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 293 1.4E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20090 85e6585c38106756d3b5616e6d99932e 294 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 15 57 1.1E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS20090 85e6585c38106756d3b5616e6d99932e 294 SUPERFAMILY SSF161098 87 274 1.23E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20090 85e6585c38106756d3b5616e6d99932e 294 Gene3D G3DSA:1.10.3720.10 83 290 9.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24175 e188948dc342fde9caef355b031e5c2f 336 PIRSF PIRSF017082 9 335 1.6E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24175 e188948dc342fde9caef355b031e5c2f 336 SUPERFAMILY SSF53850 111 296 2.1E-16 T 06-07-2017 CAL12_RS24175 e188948dc342fde9caef355b031e5c2f 336 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 60 332 6.3E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07550 90566fa67cbac5ef5f92cdc3fc58131c 182 Gene3D G3DSA:3.40.50.360 3 180 9.1E-45 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS07550 90566fa67cbac5ef5f92cdc3fc58131c 182 SUPERFAMILY SSF52218 4 178 3.03E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS07550 90566fa67cbac5ef5f92cdc3fc58131c 182 Pfam PF03358 NADPH-dependent FMN reductase 4 142 2.6E-30 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAL12_RS19815 25f1235a7fdc4c7a793d72505f30fbcd 470 Gene3D G3DSA:1.20.1250.20 280 467 1.3E-17 T 06-07-2017 CAL12_RS19815 25f1235a7fdc4c7a793d72505f30fbcd 470 Gene3D G3DSA:1.20.1250.20 35 228 4.7E-21 T 06-07-2017 CAL12_RS19815 25f1235a7fdc4c7a793d72505f30fbcd 470 Pfam PF00083 Sugar (and other) transporter 36 469 3.7E-33 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS19815 25f1235a7fdc4c7a793d72505f30fbcd 470 SUPERFAMILY SSF103473 20 468 2.88E-67 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS03360 79a4e7c35cfd6a5f4d1ac8c5e9da5ba7 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 313 4.0E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03360 79a4e7c35cfd6a5f4d1ac8c5e9da5ba7 318 SUPERFAMILY SSF53850 109 276 8.14E-7 T 06-07-2017 CAL12_RS03360 79a4e7c35cfd6a5f4d1ac8c5e9da5ba7 318 PIRSF PIRSF017082 3 317 2.1E-63 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 SUPERFAMILY SSF56235 415 611 7.13E-134 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 SUPERFAMILY SSF56235 6 357 7.13E-134 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 Pfam PF01019 Gamma-glutamyltranspeptidase 32 604 3.1E-116 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 496 513 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 487 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 279 298 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12700 4f289409b0dc802f40634f088dfe6182 612 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 39 64 3.4E-17 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 Gene3D G3DSA:3.40.50.300 5 226 2.1E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 Gene3D G3DSA:3.40.50.300 238 461 3.0E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 SUPERFAMILY SSF52540 4 225 8.64E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 SUPERFAMILY SSF52540 241 459 6.88E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 Pfam PF06745 KaiC 9 223 1.2E-26 T 06-07-2017 IPR014774 KaiC-like domain CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 Pfam PF06745 KaiC 245 460 1.6E-29 T 06-07-2017 IPR014774 KaiC-like domain CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 PIRSF PIRSF039117 1 472 2.2E-112 T 06-07-2017 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 SMART SM00382 260 422 0.35 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09975 b9a1aca2e1ba08b6e698132cf0f35e31 477 SMART SM00382 24 186 0.0034 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 Pfam PF03023 MviN-like protein 21 469 1.0E-88 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PIRSF PIRSF002869 1 510 4.1E-95 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 352 371 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 25 44 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 44 60 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 123 147 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 414 431 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 250 276 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 PRINTS PR01806 Virulence factor MviN signature 147 168 1.8E-35 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS19945 17c6111b005c2d4ba42e020dd9c9f185 515 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 1 501 5.3E-91 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 Gene3D G3DSA:3.40.190.10 177 265 3.2E-19 T 06-07-2017 CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.9E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 SUPERFAMILY SSF46785 1 112 1.69E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 Gene3D G3DSA:3.40.190.10 92 176 1.0E-21 T 06-07-2017 CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 Gene3D G3DSA:1.10.10.10 4 87 1.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 Pfam PF03466 LysR substrate binding domain 89 292 5.3E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS22880 c72ca09ae165b4ca014206bba9607f09 293 SUPERFAMILY SSF53850 90 293 7.19E-40 T 06-07-2017 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 Gene3D G3DSA:1.10.10.60 217 264 8.0E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 Gene3D G3DSA:3.40.50.880 4 216 1.2E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 Pfam PF12833 Helix-turn-helix domain 233 311 2.0E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 SUPERFAMILY SSF52317 4 193 3.79E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 SUPERFAMILY SSF46689 210 257 5.82E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 SUPERFAMILY SSF46689 263 314 9.47E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 Pfam PF01965 DJ-1/PfpI family 4 172 7.3E-20 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 SMART SM00342 227 310 4.1E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01285 13250acae128f17866b4d2fee3a7d129 329 Gene3D G3DSA:1.10.10.60 265 314 3.3E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 402 1.6E-156 T 06-07-2017 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 5.5E-29 T 06-07-2017 IPR003004 GspF/PilC family CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 5.5E-29 T 06-07-2017 IPR003004 GspF/PilC family CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 5.5E-29 T 06-07-2017 IPR003004 GspF/PilC family CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 5.5E-29 T 06-07-2017 IPR003004 GspF/PilC family CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 7.1E-29 T 06-07-2017 IPR018076 Type II secretion system F domain CAL12_RS27360 f9dc2c3de15124deb15bca7c0ba96af3 403 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 2.7E-32 T 06-07-2017 IPR018076 Type II secretion system F domain CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 PIRSF PIRSF002741 6 531 8.9E-92 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 Gene3D G3DSA:3.10.105.10 317 509 2.4E-55 T 06-07-2017 CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 SUPERFAMILY SSF53850 23 521 2.9E-123 T 06-07-2017 CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 Gene3D G3DSA:3.40.190.10 205 316 1.6E-35 T 06-07-2017 CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 Gene3D G3DSA:3.90.76.10 35 204 1.1E-34 T 06-07-2017 CAL12_RS01750 5e86e664f482921ef87b99db05ae9238 544 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 454 2.8E-86 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 SUPERFAMILY SSF52518 362 540 7.12E-39 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 172 1.3E-49 T 06-07-2017 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 SUPERFAMILY SSF52518 5 174 5.4E-49 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 SUPERFAMILY SSF52467 156 346 3.0E-17 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 532 4.2E-25 T 06-07-2017 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Gene3D G3DSA:3.40.50.970 336 536 4.0E-41 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Gene3D G3DSA:3.40.50.1220 187 332 1.3E-15 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 300 3.5E-8 T 06-07-2017 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CAL12_RS07855 75a78d163908800863db38b61e3714c4 548 Gene3D G3DSA:3.40.50.970 4 177 7.5E-57 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS03150 9419b0b331a3a73166059620405f0853 347 SUPERFAMILY SSF103481 73 168 7.59E-12 T 06-07-2017 CAL12_RS03150 9419b0b331a3a73166059620405f0853 347 Pfam PF00892 EamA-like transporter family 174 300 2.7E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS03150 9419b0b331a3a73166059620405f0853 347 Pfam PF00892 EamA-like transporter family 29 164 2.9E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS03150 9419b0b331a3a73166059620405f0853 347 SUPERFAMILY SSF103481 220 308 4.97E-13 T 06-07-2017 CAL12_RS04345 2f9cbddb6c1718d90f395aec17444a86 207 PIRSF PIRSF006324 1 202 6.7E-47 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS04345 2f9cbddb6c1718d90f395aec17444a86 207 Pfam PF01810 LysE type translocator 9 200 1.7E-32 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 270 2.1E-72 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 SUPERFAMILY SSF51735 6 163 1.32E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 270 24.989 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 Gene3D G3DSA:1.10.3730.10 167 270 3.3E-37 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 Gene3D G3DSA:3.40.50.720 4 163 3.6E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 99 2.8E-10 T 06-07-2017 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 PIRSF PIRSF000193 5 273 1.1E-68 T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 SUPERFAMILY SSF48179 166 274 1.02E-34 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 225 248 - T 06-07-2017 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CAL12_RS15520 bb31e020540e69e750b9368efcb6aef9 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 168 270 4.3E-36 T 06-07-2017 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 Gene3D G3DSA:2.40.170.20 179 773 2.9E-79 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 SUPERFAMILY SSF56935 285 773 5.5E-101 T 06-07-2017 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 SUPERFAMILY SSF56935 39 242 5.5E-101 T 06-07-2017 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 Pfam PF00593 TonB dependent receptor 527 773 9.8E-38 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 Gene3D G3DSA:2.170.130.10 40 178 2.9E-20 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS07770 706526e87381d96f31c4b6bf807818b3 776 Pfam PF07715 TonB-dependent Receptor Plug Domain 64 174 9.3E-15 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 SUPERFAMILY SSF53474 58 351 1.99E-53 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 Gene3D G3DSA:3.40.50.1820 60 351 4.5E-52 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 Pfam PF00561 alpha/beta hydrolase fold 81 197 5.3E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 PRINTS PR00412 Epoxide hydrolase signature 169 182 1.1E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 PRINTS PR00412 Epoxide hydrolase signature 155 168 1.1E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 PRINTS PR00412 Epoxide hydrolase signature 328 350 1.1E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 PRINTS PR00412 Epoxide hydrolase signature 87 105 1.1E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS27220 288d8a5305aafa6810751adda1eaa156 353 PRINTS PR00412 Epoxide hydrolase signature 107 122 1.1E-12 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 PIRSF PIRSF000194 11 171 5.4E-61 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 Gene3D G3DSA:3.40.430.10 13 170 1.0E-60 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 Pfam PF00186 Dihydrofolate reductase 15 170 2.1E-57 T 06-07-2017 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 SUPERFAMILY SSF53597 14 170 8.64E-58 T 06-07-2017 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 26 48 - T 06-07-2017 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-113510|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-69205 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 PRINTS PR00070 Dihydrofolate reductase signature 40 48 6.2E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 PRINTS PR00070 Dihydrofolate reductase signature 53 64 6.2E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 PRINTS PR00070 Dihydrofolate reductase signature 26 36 6.2E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS02680 d03fd74b6bf142013e3746aad739ffcd 171 PRINTS PR00070 Dihydrofolate reductase signature 104 118 6.2E-16 T 06-07-2017 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CAL12_RS19915 405ba5f9691e301ac7074066be520da8 291 Pfam PF01226 Formate/nitrite transporter 34 270 8.5E-42 T 06-07-2017 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CAL12_RS19915 405ba5f9691e301ac7074066be520da8 291 Gene3D G3DSA:1.20.1080.10 47 272 4.9E-43 T 06-07-2017 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CAL12_RS22560 a58c6b0ee43aa7c354f192dbd06eef0b 148 SUPERFAMILY SSF57997 6 139 7.85E-6 T 06-07-2017 CAL12_RS22560 a58c6b0ee43aa7c354f192dbd06eef0b 148 Pfam PF09787 Golgin subfamily A member 5 19 122 1.0E-6 T 06-07-2017 IPR019177 Golgin subfamily A member 5 GO:0007030 Reactome: R-HSA-6811438 CAL12_RS18785 5b6a5367ea0d8f201fbbe83135654e2a 102 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 94 4.4E-32 T 06-07-2017 IPR009662 Malonate decarboxylase delta subunit CAL12_RS18785 5b6a5367ea0d8f201fbbe83135654e2a 102 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 99 45.1 T 06-07-2017 IPR009662 Malonate decarboxylase delta subunit CAL12_RS18785 5b6a5367ea0d8f201fbbe83135654e2a 102 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 17 94 8.1E-24 T 06-07-2017 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein CAL12_RS18785 5b6a5367ea0d8f201fbbe83135654e2a 102 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 93 9.0E-18 T 06-07-2017 IPR009662 Malonate decarboxylase delta subunit CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 SUPERFAMILY SSF55961 873 1013 8.12E-35 T 06-07-2017 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 874 1012 2.9E-26 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 306 381 5.5E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 141 195 5.5E-35 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 671 815 2.1E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 383 475 2.1E-61 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 SMART SM01008 41 152 7.7E-45 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 SUPERFAMILY SSF54665 21 173 2.49E-42 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 41 151 1.5E-25 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 196 303 9.9E-23 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 169 756 6.0E-147 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 SUPERFAMILY SSF56003 145 815 5.23E-166 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.365.10 476 655 1.1E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.30.530.20 873 1020 3.5E-43 T 06-07-2017 IPR023393 START-like domain CAL12_RS03305 7df7092fef832f40577af87ea3927224 1043 Gene3D G3DSA:3.90.1170.50 17 140 4.6E-39 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS22425 819de5bcbe5e5988d39cb80dfac5714a 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 389 2.9E-124 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS22425 819de5bcbe5e5988d39cb80dfac5714a 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS22425 819de5bcbe5e5988d39cb80dfac5714a 389 Pfam PF00953 Glycosyl transferase family 4 99 306 6.6E-37 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAL12_RS22425 819de5bcbe5e5988d39cb80dfac5714a 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 06-07-2017 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS22425 819de5bcbe5e5988d39cb80dfac5714a 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.816 T 06-07-2017 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 Gene3D G3DSA:2.30.330.10 87 176 1.4E-39 T 06-07-2017 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 SUPERFAMILY SSF101801 93 175 1.7E-26 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 93 167 3.9E-34 T 06-07-2017 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 96 166 4.0E-26 T 06-07-2017 IPR001543 Surface presentation of antigen (SpoA) CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 PRINTS PR00956 Flagellar motor switch protein FliN signature 142 157 3.7E-30 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 PRINTS PR00956 Flagellar motor switch protein FliN signature 129 142 3.7E-30 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 PRINTS PR00956 Flagellar motor switch protein FliN signature 96 112 3.7E-30 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAL12_RS11985 fe34023b4d29b3f1a61bd8bdb3556a91 179 PRINTS PR00956 Flagellar motor switch protein FliN signature 113 129 3.7E-30 T 06-07-2017 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CAL12_RS27390 edf2984ac86783edd671d21b1f966876 223 Pfam PF10707 PhoP regulatory network protein YrbL 23 180 9.4E-24 T 06-07-2017 IPR019647 PhoP regulatory network protein YrbL CAL12_RS27390 edf2984ac86783edd671d21b1f966876 223 SUPERFAMILY SSF56112 23 171 6.45E-5 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 SUPERFAMILY SSF46785 16 125 1.23E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 3.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 3.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 3.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 SUPERFAMILY SSF53850 105 316 1.86E-39 T 06-07-2017 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 Gene3D G3DSA:1.10.10.10 16 100 4.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 Pfam PF03466 LysR substrate binding domain 103 314 7.7E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 Gene3D G3DSA:3.40.190.10 107 201 2.7E-18 T 06-07-2017 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 9.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07665 559cc5288dae69ff4fd6a039066b0dc0 329 Gene3D G3DSA:3.40.190.10 202 281 5.7E-15 T 06-07-2017 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Gene3D G3DSA:1.10.3720.10 318 498 2.3E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 341 513 6.9E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 SUPERFAMILY SSF53850 38 292 1.9E-50 T 06-07-2017 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 38 290 5.0E-49 T 06-07-2017 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Gene3D G3DSA:3.40.190.10 37 140 6.3E-33 T 06-07-2017 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Gene3D G3DSA:3.40.190.10 248 290 6.3E-33 T 06-07-2017 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 SUPERFAMILY SSF161098 320 514 9.29E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08990 483c97f747275ef1a3a83cb479e217d3 522 Gene3D G3DSA:3.40.190.120 141 235 3.6E-30 T 06-07-2017 CAL12_RS08065 afe0926672ced588de1d5f84b605cd3d 323 Pfam PF01904 Protein of unknown function DUF72 43 316 2.4E-61 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08065 afe0926672ced588de1d5f84b605cd3d 323 SUPERFAMILY SSF117396 22 103 2.22E-69 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08065 afe0926672ced588de1d5f84b605cd3d 323 SUPERFAMILY SSF117396 129 320 2.22E-69 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS08065 afe0926672ced588de1d5f84b605cd3d 323 Gene3D G3DSA:3.20.20.410 20 321 5.9E-88 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 SMART SM00490 293 373 1.7E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 SMART SM00487 25 250 4.5E-28 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 SUPERFAMILY SSF52540 246 376 2.85E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 SUPERFAMILY SSF52540 38 218 2.85E-46 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 Pfam PF08494 DEAD/H associated 666 868 3.5E-55 T 06-07-2017 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 Gene3D G3DSA:3.40.50.300 18 214 4.5E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 Pfam PF00271 Helicase conserved C-terminal domain 275 373 7.3E-18 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 Gene3D G3DSA:3.40.50.300 262 378 4.0E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10740 03c93b028b2bfd2fcc32f0cc811f3b1b 1524 Pfam PF00270 DEAD/DEAH box helicase 30 216 2.1E-25 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 85 2.0E-33 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 Gene3D G3DSA:2.60.15.10 1 88 2.4E-31 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 21.655 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 SUPERFAMILY SSF46604 88 132 3.66E-6 T 06-07-2017 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 127 2.4E-40 T 06-07-2017 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 SUPERFAMILY SSF51344 3 85 3.79E-25 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS25790 14833a02e588b89957c4f982e0ca7bee 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 4.5E-29 T 06-07-2017 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 SUPERFAMILY SSF54913 1 112 5.4E-43 T 06-07-2017 IPR011322 Nitrogen regulatory PII-like, alpha/beta CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 Gene3D G3DSA:3.30.70.120 1 112 1.4E-48 T 06-07-2017 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 7.5E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 SMART SM00938 4 105 5.2E-63 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 06-07-2017 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 PIRSF PIRSF039144 1 112 1.8E-51 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 06-07-2017 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 PRINTS PR00340 P-II protein signature 52 75 1.7E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 PRINTS PR00340 P-II protein signature 2 17 1.7E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 PRINTS PR00340 P-II protein signature 83 103 1.7E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS09875 d1764b95a29fbd05ad9122e2ff8831d1 112 PRINTS PR00340 P-II protein signature 23 41 1.7E-41 T 06-07-2017 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CAL12_RS01180 40809ad4dc0d759af831fc92683ed7c7 180 Pfam PF03473 MOSC domain 58 166 5.1E-5 T 06-07-2017 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CAL12_RS01180 40809ad4dc0d759af831fc92683ed7c7 180 Gene3D G3DSA:2.40.33.20 1 180 2.1E-61 T 06-07-2017 IPR015808 Molybdenum cofactor sulfurase, C-terminal-like CAL12_RS01180 40809ad4dc0d759af831fc92683ed7c7 180 SUPERFAMILY SSF50800 1 170 1.31E-38 T 06-07-2017 IPR011037 Pyruvate kinase-like, insert domain CAL12_RS24300 cc7d4265a4c5da5706829a284f29bec4 307 Gene3D G3DSA:1.10.3720.10 90 302 4.4E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24300 cc7d4265a4c5da5706829a284f29bec4 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 305 2.8E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24300 cc7d4265a4c5da5706829a284f29bec4 307 SUPERFAMILY SSF161098 91 288 4.14E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06305 1cb4c702b1e99a20926356b436e87511 381 Gene3D G3DSA:3.90.1510.10 42 274 2.6E-93 T 06-07-2017 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CAL12_RS06305 1cb4c702b1e99a20926356b436e87511 381 SUPERFAMILY SSF110738 2 373 2.48E-128 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAL12_RS06305 1cb4c702b1e99a20926356b436e87511 381 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 372 3.2E-145 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAL12_RS06305 1cb4c702b1e99a20926356b436e87511 381 PIRSF PIRSF006078 1 376 7.5E-128 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAL12_RS06305 1cb4c702b1e99a20926356b436e87511 381 Pfam PF02595 Glycerate kinase family 3 372 2.5E-143 T 06-07-2017 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF13176 Tetratricopeptide repeat 794 819 0.022 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 PRINTS PR01441 Cellulose synthase subunit C signature 1239 1263 1.7E-16 T 06-07-2017 IPR003921 Cellulose synthase, subunit C GO:0006011|GO:0016020 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 PRINTS PR01441 Cellulose synthase subunit C signature 36 56 1.7E-16 T 06-07-2017 IPR003921 Cellulose synthase, subunit C GO:0006011|GO:0016020 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 PRINTS PR01441 Cellulose synthase subunit C signature 148 160 1.7E-16 T 06-07-2017 IPR003921 Cellulose synthase, subunit C GO:0006011|GO:0016020 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 PRINTS PR01441 Cellulose synthase subunit C signature 1279 1300 1.7E-16 T 06-07-2017 IPR003921 Cellulose synthase, subunit C GO:0006011|GO:0016020 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 PRINTS PR01441 Cellulose synthase subunit C signature 213 235 1.7E-16 T 06-07-2017 IPR003921 Cellulose synthase, subunit C GO:0006011|GO:0016020 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Gene3D G3DSA:1.25.40.10 242 262 5.7E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Gene3D G3DSA:1.25.40.10 29 161 5.7E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 464 497 270.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 757 790 20.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 723 756 5.7 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 28 61 83.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 791 824 22.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 62 95 2.4 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 311 344 19.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 354 387 9.7 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 388 421 11.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SMART SM00028 112 145 180.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) 1031 1381 3.0E-110 T 06-07-2017 IPR008410 Cellulose synthase operon C, C-terminal GO:0019867|GO:0030244 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF13432 Tetratricopeptide repeat 285 340 9.9E-8 T 06-07-2017 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Gene3D G3DSA:1.25.40.10 694 820 7.6E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF14559 Tetratricopeptide repeat 52 103 5.5E-6 T 06-07-2017 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF14559 Tetratricopeptide repeat 700 760 3.4E-7 T 06-07-2017 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF14559 Tetratricopeptide repeat 474 537 6.5E-9 T 06-07-2017 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Pfam PF14559 Tetratricopeptide repeat 400 454 4.8E-6 T 06-07-2017 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SUPERFAMILY SSF48452 711 821 2.37E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SUPERFAMILY SSF48452 470 637 2.78E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Gene3D G3DSA:1.25.40.10 470 670 1.6E-16 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 Gene3D G3DSA:1.25.40.10 287 442 1.3E-21 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SUPERFAMILY SSF48452 35 187 1.01E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS00275 2e2102ae8897b126e4edf53c22b2b4f2 1400 SUPERFAMILY SSF48452 283 444 1.01E-19 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS16580 3f3703ada56cd5267c34a2c49f0966c4 77 SUPERFAMILY SSF55174 10 71 4.32E-15 T 06-07-2017 CAL12_RS16580 3f3703ada56cd5267c34a2c49f0966c4 77 Gene3D G3DSA:3.10.290.10 13 71 1.3E-20 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS16580 3f3703ada56cd5267c34a2c49f0966c4 77 Pfam PF13275 S4 domain 13 71 2.4E-19 T 06-07-2017 CAL12_RS12930 64dc66001d7b98cb1ed66df6d2f64e2d 376 Gene3D G3DSA:3.90.1150.10 235 368 1.2E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS12930 64dc66001d7b98cb1ed66df6d2f64e2d 376 SUPERFAMILY SSF53383 45 367 2.93E-72 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS12930 64dc66001d7b98cb1ed66df6d2f64e2d 376 Pfam PF00155 Aminotransferase class I and II 42 358 6.5E-45 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS12930 64dc66001d7b98cb1ed66df6d2f64e2d 376 Gene3D G3DSA:3.40.640.10 43 234 7.7E-48 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 SUPERFAMILY SSF52096 302 547 1.06E-14 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 Gene3D G3DSA:3.90.226.10 16 230 6.0E-33 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 Gene3D G3DSA:3.90.226.10 303 479 1.9E-8 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 Pfam PF00378 Enoyl-CoA hydratase/isomerase 49 238 1.4E-21 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 8 552 2.9E-291 T 06-07-2017 IPR017633 Benzoyl-CoA-dihydrodiol lyase MetaCyc: PWY-1361 CAL12_RS05285 0a995674536d628f12eca20e81385d82 552 SUPERFAMILY SSF52096 16 255 7.17E-30 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 Pfam PF07690 Major Facilitator Superfamily 7 400 2.1E-53 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 409 1.3E-70 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 PRINTS PR01035 Tetracycline resistance protein signature 13 29 1.8E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 PRINTS PR01035 Tetracycline resistance protein signature 127 149 1.8E-5 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 SUPERFAMILY SSF103473 238 410 3.53E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 SUPERFAMILY SSF103473 2 182 3.53E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 SUPERFAMILY SSF103473 454 478 3.53E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 Gene3D G3DSA:1.20.1250.20 253 411 1.4E-22 T 06-07-2017 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 Gene3D G3DSA:1.20.1250.20 455 479 1.4E-22 T 06-07-2017 CAL12_RS06900 285f3eb300764946eaba917385d71e6c 494 Gene3D G3DSA:1.20.1250.20 3 172 4.0E-32 T 06-07-2017 CAL12_RS07840 baea2e1572a09fe0957a2ba400741c2b 204 Gene3D G3DSA:3.20.130.10 2 182 3.0E-50 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS07840 baea2e1572a09fe0957a2ba400741c2b 204 Pfam PF05683 Fumarase C-terminus 8 183 1.0E-27 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS07840 baea2e1572a09fe0957a2ba400741c2b 204 SUPERFAMILY SSF117457 5 182 1.83E-40 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS05895 c0d4346313ce6a8b7d823be5cb0bd3e5 511 Pfam PF08309 LVIVD repeat 215 234 0.024 T 06-07-2017 IPR013211 LVIVD CAL12_RS05895 c0d4346313ce6a8b7d823be5cb0bd3e5 511 Pfam PF08309 LVIVD repeat 421 437 2.0 T 06-07-2017 IPR013211 LVIVD CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SMART SM00086 218 260 6.2E-6 T 06-07-2017 IPR001610 PAC motif CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 398 488 2.0E-6 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SUPERFAMILY SSF55874 358 487 2.49E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Gene3D G3DSA:3.30.450.20 143 258 7.2E-21 T 06-07-2017 CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SMART SM00387 395 489 4.0E-8 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Gene3D G3DSA:3.30.565.10 377 489 7.9E-13 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SUPERFAMILY SSF55785 159 262 1.92E-17 T 06-07-2017 IPR000014 PAS domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SUPERFAMILY SSF52172 5 152 2.28E-27 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Pfam PF00072 Response regulator receiver domain 8 118 9.3E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Pfam PF07730 Histidine kinase 288 355 8.1E-14 T 06-07-2017 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 267 1.4E-14 T 06-07-2017 IPR000014 PAS domain CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 SMART SM00448 6 125 7.5E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Pfam PF08447 PAS fold 169 253 3.0E-17 T 06-07-2017 IPR013655 PAS fold-3 GO:0005515 CAL12_RS14365 bc84fee76bdfa7918e3122d45ce301ce 493 Gene3D G3DSA:3.40.50.2300 3 142 2.1E-25 T 06-07-2017 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 SUPERFAMILY SSF52540 129 290 3.94E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 SUPERFAMILY SSF47413 17 85 4.56E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 Pfam PF01381 Helix-turn-helix 26 79 9.2E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 Gene3D G3DSA:3.40.50.300 128 295 4.7E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 Hamap MF_00109 Shikimate kinase [aroK]. 127 294 19.712 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 Pfam PF01202 Shikimate kinase 136 278 2.5E-30 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 SMART SM00530 24 79 5.2E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 PRINTS PR01100 Shikimate kinase family signature 182 190 7.1E-12 T 06-07-2017 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 PRINTS PR01100 Shikimate kinase family signature 154 167 7.1E-12 T 06-07-2017 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 PRINTS PR01100 Shikimate kinase family signature 130 145 7.1E-12 T 06-07-2017 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 PRINTS PR01100 Shikimate kinase family signature 201 210 7.1E-12 T 06-07-2017 CAL12_RS05280 2e6461cb305033c99d862d8dbb6cc7bc 301 Gene3D G3DSA:1.10.260.40 16 88 3.3E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS06235 392b7fe821243c8209fa950f57000245 111 SUPERFAMILY SSF52833 4 107 3.32E-15 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS06235 392b7fe821243c8209fa950f57000245 111 Gene3D G3DSA:3.40.30.10 24 105 9.0E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS13200 dbe5cd7d8ad6547c82918e172c660780 305 SUPERFAMILY SSF52540 81 269 3.33E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13200 dbe5cd7d8ad6547c82918e172c660780 305 Gene3D G3DSA:3.40.50.300 42 288 4.6E-106 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13200 dbe5cd7d8ad6547c82918e172c660780 305 PIRSF PIRSF028756 12 305 8.7E-135 T 06-07-2017 IPR016898 Polyphosphate kinase 2 CAL12_RS13200 dbe5cd7d8ad6547c82918e172c660780 305 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 52 275 1.7E-114 T 06-07-2017 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CAL12_RS13200 dbe5cd7d8ad6547c82918e172c660780 305 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 52 276 3.2E-112 T 06-07-2017 IPR022488 Polyphosphate kinase-2-related CAL12_RS13765 938f32df65781b3d7199b917ed076f55 455 Pfam PF00884 Sulfatase 5 328 4.1E-49 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS13765 938f32df65781b3d7199b917ed076f55 455 SUPERFAMILY SSF53649 3 406 1.16E-92 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS13765 938f32df65781b3d7199b917ed076f55 455 Gene3D G3DSA:3.40.720.10 3 376 1.6E-89 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS17755 a7ada004c483bb1d0864f5afe69b4da5 479 SUPERFAMILY SSF52467 307 479 3.02E-75 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS17755 a7ada004c483bb1d0864f5afe69b4da5 479 PIRSF PIRSF000204 2 479 4.1E-210 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS17755 a7ada004c483bb1d0864f5afe69b4da5 479 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 476 2.0E-186 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS17755 a7ada004c483bb1d0864f5afe69b4da5 479 Gene3D G3DSA:3.40.50.1220 303 479 1.3E-86 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS00955 f7c0bf2e94b1ef7670f8324ef2f5da01 836 Gene3D G3DSA:2.60.120.10 696 819 1.8E-21 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS00955 f7c0bf2e94b1ef7670f8324ef2f5da01 836 SMART SM00100 703 815 7.8E-11 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS00955 f7c0bf2e94b1ef7670f8324ef2f5da01 836 Pfam PF00999 Sodium/hydrogen exchanger family 13 413 6.1E-58 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS00955 f7c0bf2e94b1ef7670f8324ef2f5da01 836 Pfam PF00027 Cyclic nucleotide-binding domain 734 802 5.5E-10 T 06-07-2017 IPR000595 Cyclic nucleotide-binding domain CAL12_RS00955 f7c0bf2e94b1ef7670f8324ef2f5da01 836 SUPERFAMILY SSF51206 695 819 1.27E-21 T 06-07-2017 IPR018490 Cyclic nucleotide-binding-like CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 Pfam PF02803 Thiolase, C-terminal domain 260 357 6.3E-7 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 Gene3D G3DSA:3.40.47.10 198 228 4.9E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 Gene3D G3DSA:3.40.47.10 26 113 4.9E-17 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 SUPERFAMILY SSF53901 184 359 3.17E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 SUPERFAMILY SSF53901 22 117 3.17E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 PIRSF PIRSF000429 6 382 1.2E-29 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 Gene3D G3DSA:3.40.47.10 150 186 3.0E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS24420 dba5cf4324f6bd2630151398acc77632 389 Gene3D G3DSA:3.40.47.10 246 371 3.0E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS02115 61578b8cea5d0d9aa4448c902e9a0f5e 399 SUPERFAMILY SSF51004 36 347 7.85E-18 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CAL12_RS02115 61578b8cea5d0d9aa4448c902e9a0f5e 399 Pfam PF10282 Lactonase, 7-bladed beta-propeller 51 348 2.0E-22 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAL12_RS02115 61578b8cea5d0d9aa4448c902e9a0f5e 399 Gene3D G3DSA:2.130.10.10 48 349 1.4E-24 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 2.2E-95 T 06-07-2017 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 SUPERFAMILY SSF103491 13 419 1.57E-134 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 424 8.7E-136 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 Gene3D G3DSA:1.10.3370.10 13 432 1.8E-170 T 06-07-2017 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 Pfam PF00344 SecY translocase 74 412 3.2E-119 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 428 29.441 T 06-07-2017 IPR026593 Protein translocase subunit SecY CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 06-07-2017 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS27525 920c18d782cc0d38d90b68e93b749b9c 443 PIRSF PIRSF004557 9 436 1.4E-126 T 06-07-2017 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 Gene3D G3DSA:1.10.10.10 5 87 2.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 SUPERFAMILY SSF46785 3 84 8.16E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 4.7E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 Gene3D G3DSA:3.40.190.10 93 179 5.0E-19 T 06-07-2017 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 Gene3D G3DSA:3.40.190.10 180 266 1.4E-21 T 06-07-2017 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 Pfam PF03466 LysR substrate binding domain 92 293 3.4E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03410 1a644876f8765813b3130ca629faa3b6 303 SUPERFAMILY SSF53850 94 297 5.19E-34 T 06-07-2017 CAL12_RS06540 c8ea072fe8f735d391033da5c299b9a4 201 SMART SM01103 6 89 9.6E-33 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 CAL12_RS06540 c8ea072fe8f735d391033da5c299b9a4 201 Gene3D G3DSA:3.30.110.60 5 93 1.5E-25 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 CAL12_RS06540 c8ea072fe8f735d391033da5c299b9a4 201 Pfam PF01985 CRS1 / YhbY (CRM) domain 7 89 7.0E-16 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 CAL12_RS06540 c8ea072fe8f735d391033da5c299b9a4 201 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 23 89 2.0E-24 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 CAL12_RS06540 c8ea072fe8f735d391033da5c299b9a4 201 SUPERFAMILY SSF75471 5 94 5.1E-23 T 06-07-2017 IPR001890 RNA-binding, CRM domain GO:0003723 CAL12_RS20175 e5df45bc689dd20eedfaea384d1d0ace 597 Pfam PF00437 Type II/IV secretion system protein 256 427 4.0E-21 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS20175 e5df45bc689dd20eedfaea384d1d0ace 597 Gene3D G3DSA:3.40.50.300 274 583 1.0E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20175 e5df45bc689dd20eedfaea384d1d0ace 597 SUPERFAMILY SSF52540 487 547 1.33E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20175 e5df45bc689dd20eedfaea384d1d0ace 597 SUPERFAMILY SSF52540 155 458 1.33E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20175 e5df45bc689dd20eedfaea384d1d0ace 597 Gene3D G3DSA:3.30.450.90 152 266 1.4E-4 T 06-07-2017 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 Pfam PF13609 Gram-negative porin 9 348 4.3E-49 T 06-07-2017 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 Gene3D G3DSA:2.40.160.10 33 373 1.9E-75 T 06-07-2017 IPR023614 Porin domain CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 PRINTS PR00184 Neisseria sp. porin signature 62 87 5.6E-7 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 PRINTS PR00184 Neisseria sp. porin signature 161 178 5.6E-7 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 PRINTS PR00184 Neisseria sp. porin signature 197 214 5.6E-7 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 PRINTS PR00184 Neisseria sp. porin signature 322 346 5.6E-7 T 06-07-2017 IPR002299 Porin, Neisseria sp. type GO:0006810|GO:0015288|GO:0016020 CAL12_RS05665 4c72988963d5ac6f1d29c819c8d204f9 373 SUPERFAMILY SSF56935 32 373 2.29E-62 T 06-07-2017 CAL12_RS20415 2130d18706fc3ecae20ec16398ad6a16 619 Pfam PF01594 Domain of unknown function DUF20 23 364 1.5E-43 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAL12_RS02285 a405977746ab47e75498e52a7507e1b8 289 SUPERFAMILY SSF161098 83 269 1.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02285 a405977746ab47e75498e52a7507e1b8 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 269 3.3E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02285 a405977746ab47e75498e52a7507e1b8 289 Gene3D G3DSA:1.10.3720.10 83 278 5.3E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 SUPERFAMILY SSF52540 2 376 1.95E-98 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1125 0.0 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 PIRSF PIRSF000980 1 1188 0.0 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 Gene3D G3DSA:1.10.10.160 93 199 3.4E-32 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1225 19.59 T 06-07-2017 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 SUPERFAMILY SSF52980 870 1218 2.2E-47 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 2 858 9.2E-268 T 06-07-2017 CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 Gene3D G3DSA:3.40.50.300 389 479 5.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 Gene3D G3DSA:3.40.50.300 686 783 5.8E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01555 91dafc0274faa2f876edf91367485866 1241 SUPERFAMILY SSF52540 391 861 4.25E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 3.7E-19 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 SUPERFAMILY SSF54909 61 149 1.17E-19 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 SUPERFAMILY SSF46785 1 60 3.2E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 Gene3D G3DSA:1.10.10.10 1 49 1.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 SMART SM00344 1 110 1.2E-41 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 06-07-2017 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 7.0E-19 T 06-07-2017 CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 Gene3D G3DSA:3.30.70.920 54 137 1.2E-29 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.2E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.2E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS22330 df455c6483e6abde37d9f7fe809481c8 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.2E-12 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 Gene3D G3DSA:3.40.50.2300 1 126 3.4E-13 T 06-07-2017 CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 PIRSF PIRSF036382 1 191 7.2E-52 T 06-07-2017 IPR008327 Signal transduction response regulator, antiterminator CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 Pfam PF00072 Response regulator receiver domain 5 111 6.8E-8 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 SUPERFAMILY SSF52172 1 183 1.99E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 SMART SM01012 129 184 1.9E-17 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 Pfam PF03861 ANTAR domain 134 184 4.8E-16 T 06-07-2017 IPR005561 ANTAR domain GO:0003723 CAL12_RS07055 bdce535344951346f7a0977e5cc152d8 192 Gene3D G3DSA:1.10.10.10 133 190 6.8E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 Gene3D G3DSA:3.40.50.620 4 174 1.9E-44 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 443 69.129 T 06-07-2017 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 Gene3D G3DSA:1.10.287.400 377 440 2.7E-33 T 06-07-2017 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 06-07-2017 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 5.2E-157 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 Gene3D G3DSA:3.90.1260.10 175 373 7.3E-65 T 06-07-2017 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 SUPERFAMILY SSF52402 4 185 7.91E-33 T 06-07-2017 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 Pfam PF00764 Arginosuccinate synthase 16 410 7.3E-61 T 06-07-2017 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS17530 8270949305996a37652cf935d65aeb90 444 SUPERFAMILY SSF69864 190 442 4.58E-79 T 06-07-2017 CAL12_RS13115 ef8eef69682ef19f73f97bd1beba08b6 92 Pfam PF13616 PPIC-type PPIASE domain 7 91 7.0E-23 T 06-07-2017 CAL12_RS13115 ef8eef69682ef19f73f97bd1beba08b6 92 SUPERFAMILY SSF54534 3 92 4.38E-29 T 06-07-2017 CAL12_RS13115 ef8eef69682ef19f73f97bd1beba08b6 92 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 06-07-2017 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-936440 CAL12_RS13115 ef8eef69682ef19f73f97bd1beba08b6 92 Gene3D G3DSA:3.10.50.40 3 92 9.9E-35 T 06-07-2017 CAL12_RS05080 c613a7e3ff727a96716a5fcfbd3a4aed 330 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 289 8.8E-101 T 06-07-2017 IPR017797 Phosphonate ABC transporter, periplasmic substrate-binding protein GO:0015604|GO:0015716|GO:0043190 CAL12_RS05080 c613a7e3ff727a96716a5fcfbd3a4aed 330 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 8 250 9.9E-72 T 06-07-2017 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 CAL12_RS05080 c613a7e3ff727a96716a5fcfbd3a4aed 330 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 29 277 1.4E-60 T 06-07-2017 CAL12_RS05080 c613a7e3ff727a96716a5fcfbd3a4aed 330 SUPERFAMILY SSF53850 48 241 1.05E-34 T 06-07-2017 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 Gene3D G3DSA:3.40.50.150 247 445 1.8E-43 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 SUPERFAMILY SSF48013 32 166 1.31E-9 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 1.7E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 1.7E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 334 346 1.7E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 384 400 1.7E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 428 445 1.7E-23 T 06-07-2017 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 Gene3D G3DSA:1.10.287.730 166 186 1.9E-6 T 06-07-2017 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 Gene3D G3DSA:1.10.940.10 42 165 9.1E-9 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 SUPERFAMILY SSF53335 156 445 5.11E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 333 344 - T 06-07-2017 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 Gene3D G3DSA:3.30.70.1170 190 245 6.8E-21 T 06-07-2017 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 113 445 2.8E-83 T 06-07-2017 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26270 8e7fad4378a1130e69d2fb18fb5bf3f3 447 Pfam PF01189 16S rRNA methyltransferase RsmB/F 257 443 5.6E-46 T 06-07-2017 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS24660 68739bd109079d74edb2cbb689966fbb 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 3.0E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24660 68739bd109079d74edb2cbb689966fbb 307 Gene3D G3DSA:1.10.3720.10 92 297 1.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24660 68739bd109079d74edb2cbb689966fbb 307 SUPERFAMILY SSF161098 92 292 7.72E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 SUPERFAMILY SSF51126 401 677 3.45E-15 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 Pfam PF03797 Autotransporter beta-domain 813 1068 2.0E-51 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 595 1081 5.9E-52 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 Gene3D G3DSA:2.40.128.130 761 1083 6.3E-62 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 SMART SM00869 810 1073 7.0E-49 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 SUPERFAMILY SSF103515 806 1083 1.27E-67 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS02995 5b470d98523c15a85d00667da80e7bee 1083 SUPERFAMILY SSF103515 752 779 1.27E-67 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS00450 9ebf4676c0489096df26d6bdce87d6f9 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS00450 9ebf4676c0489096df26d6bdce87d6f9 477 Gene3D G3DSA:3.40.605.10 3 259 5.1E-90 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS00450 9ebf4676c0489096df26d6bdce87d6f9 477 Pfam PF00171 Aldehyde dehydrogenase family 14 472 4.0E-154 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS00450 9ebf4676c0489096df26d6bdce87d6f9 477 Gene3D G3DSA:3.40.309.10 260 448 7.7E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS00450 9ebf4676c0489096df26d6bdce87d6f9 477 SUPERFAMILY SSF53720 3 475 6.02E-153 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS03825 63de7d5fcf22aefdebfbc16b72e3692f 367 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 27 1.5E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAL12_RS03825 63de7d5fcf22aefdebfbc16b72e3692f 367 PIRSF PIRSF039026 1 357 3.7E-123 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAL12_RS03825 63de7d5fcf22aefdebfbc16b72e3692f 367 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 44 323 1.4E-60 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 261 5.4E-60 T 06-07-2017 CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.8E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 Gene3D G3DSA:3.40.50.720 2 261 5.7E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13930 99c089fc3a65efebc9078fe4ebceeaa6 266 SUPERFAMILY SSF51735 7 261 4.62E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08045 48d9a1fbcd624a1b325628ebbf063922 314 SUPERFAMILY SSF51161 121 298 8.04E-45 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS08045 48d9a1fbcd624a1b325628ebbf063922 314 Gene3D G3DSA:1.10.3130.10 42 194 1.4E-40 T 06-07-2017 CAL12_RS08045 48d9a1fbcd624a1b325628ebbf063922 314 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 289 3.8E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS08045 48d9a1fbcd624a1b325628ebbf063922 314 Gene3D G3DSA:2.160.10.10 195 301 2.3E-25 T 06-07-2017 CAL12_RS03290 d37eb6a9f4599bfa9ce0c2db94e933b7 331 SUPERFAMILY SSF53850 17 136 1.18E-35 T 06-07-2017 CAL12_RS03290 d37eb6a9f4599bfa9ce0c2db94e933b7 331 SUPERFAMILY SSF53850 166 320 1.18E-35 T 06-07-2017 CAL12_RS03290 d37eb6a9f4599bfa9ce0c2db94e933b7 331 Pfam PF09084 NMT1/THI5 like 73 138 5.7E-6 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS03290 d37eb6a9f4599bfa9ce0c2db94e933b7 331 Gene3D G3DSA:3.40.190.10 87 189 9.3E-14 T 06-07-2017 CAL12_RS21315 7392fe5316605051610bd1e5dfb5676a 350 Gene3D G3DSA:3.20.20.100 1 322 7.3E-106 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS21315 7392fe5316605051610bd1e5dfb5676a 350 SUPERFAMILY SSF51430 1 321 9.82E-103 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS21315 7392fe5316605051610bd1e5dfb5676a 350 Pfam PF00248 Aldo/keto reductase family 15 321 2.0E-79 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS25830 05bf7159764df7ad8b5d563c9e665cf6 106 Pfam PF03899 ATP synthase I chain 3 90 1.9E-11 T 06-07-2017 IPR005598 ATP synthase protein I CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 Gene3D G3DSA:3.40.50.720 4 257 2.3E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 6.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 6.7E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 Pfam PF00106 short chain dehydrogenase 4 197 5.8E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 SUPERFAMILY SSF51735 235 257 8.06E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07455 576f7189a04484f948627d26cb61dc9f 310 SUPERFAMILY SSF51735 4 206 8.06E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Gene3D G3DSA:3.30.499.10 22 246 7.6E-70 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 21 877 0.0 T 06-07-2017 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 ProSitePatterns PS00450 Aconitase family signature 1. 414 430 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 SUPERFAMILY SSF53732 20 614 3.01E-196 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 SUPERFAMILY SSF52016 619 877 5.89E-75 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Gene3D G3DSA:3.40.1060.10 247 365 3.6E-32 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 ProSitePatterns PS01244 Aconitase family signature 2. 480 493 - T 06-07-2017 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Pfam PF00694 Aconitase C-terminal domain 679 805 3.6E-39 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Gene3D G3DSA:3.30.499.10 368 561 8.8E-60 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Pfam PF00330 Aconitase family (aconitate hydratase) 76 549 7.0E-165 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 Gene3D G3DSA:3.20.19.10 625 877 8.2E-67 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 480 493 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 171 179 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 214 229 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 418 429 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 147 160 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 200 213 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 290 303 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 276 289 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS04540 e4242111c5f49c0d98366bd6785b7e41 888 PRINTS PR00415 Aconitase family signature 370 384 9.3E-39 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS10390 4842dc1b85edf51f8e33a54b0613cde8 263 Pfam PF01844 HNH endonuclease 179 234 3.5E-8 T 06-07-2017 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CAL12_RS00495 d61467a45421849c96d9208a81b33f57 260 Gene3D G3DSA:3.40.190.10 16 141 8.2E-38 T 06-07-2017 CAL12_RS00495 d61467a45421849c96d9208a81b33f57 260 SMART SM00062 35 255 4.4E-40 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS00495 d61467a45421849c96d9208a81b33f57 260 SUPERFAMILY SSF53850 7 255 1.99E-56 T 06-07-2017 CAL12_RS00495 d61467a45421849c96d9208a81b33f57 260 Gene3D G3DSA:3.40.190.10 142 204 2.3E-12 T 06-07-2017 CAL12_RS00495 d61467a45421849c96d9208a81b33f57 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 2.3E-50 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 854 0.0 T 06-07-2017 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 SUPERFAMILY SSF53244 711 838 3.66E-23 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Pfam PF02875 Mur ligase family, glutamate ligase domain 711 790 5.2E-12 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Pfam PF08245 Mur ligase middle domain 475 686 1.2E-19 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 SUPERFAMILY SSF53623 434 724 7.72E-41 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Gene3D G3DSA:3.40.1190.10 469 703 5.0E-37 T 06-07-2017 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 SUPERFAMILY SSF56059 204 334 4.95E-36 T 06-07-2017 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 SUPERFAMILY SSF56059 370 459 4.95E-36 T 06-07-2017 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Gene3D G3DSA:3.30.470.20 201 320 1.8E-27 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Gene3D G3DSA:3.30.470.20 383 444 1.8E-27 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Pfam PF08443 RimK-like ATP-grasp domain 202 306 1.8E-7 T 06-07-2017 IPR013651 ATP-grasp fold, RimK-type CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 Gene3D G3DSA:3.90.190.20 713 838 1.8E-22 T 06-07-2017 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 473 497 - T 06-07-2017 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CAL12_RS19120 753a4c93c888673b310bd7ee78d777ff 860 SMART SM01209 203 336 0.0055 T 06-07-2017 CAL12_RS17475 1d273cc65f8bc1dce0e9da25eef0e820 345 PIRSF PIRSF018266 4 342 2.5E-79 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAL12_RS17475 1d273cc65f8bc1dce0e9da25eef0e820 345 Pfam PF04773 FecR protein 140 230 3.3E-18 T 06-07-2017 IPR006860 FecR protein CAL12_RS17475 1d273cc65f8bc1dce0e9da25eef0e820 345 Pfam PF16220 Domain of unknown function (DUF4880) 16 54 1.4E-11 T 06-07-2017 IPR032623 FecR, N-terminal CAL12_RS26385 97e22e5c60b08dc8ca734e5ca609e195 399 Gene3D G3DSA:3.40.50.450 121 269 1.7E-12 T 06-07-2017 CAL12_RS26385 97e22e5c60b08dc8ca734e5ca609e195 399 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 78 297 1.3E-73 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAL12_RS26385 97e22e5c60b08dc8ca734e5ca609e195 399 Pfam PF02481 DNA recombination-mediator protein A 80 288 2.1E-75 T 06-07-2017 IPR003488 DNA recombination-mediator protein A GO:0009294 CAL12_RS26385 97e22e5c60b08dc8ca734e5ca609e195 399 SUPERFAMILY SSF102405 88 297 3.51E-42 T 06-07-2017 CAL12_RS26385 97e22e5c60b08dc8ca734e5ca609e195 399 Gene3D G3DSA:1.10.10.10 338 388 1.7E-4 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 Pfam PF00083 Sugar (and other) transporter 52 170 2.5E-6 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 SUPERFAMILY SSF103473 6 403 1.83E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 Pfam PF07690 Major Facilitator Superfamily 225 399 1.9E-25 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 PRINTS PR01035 Tetracycline resistance protein signature 24 40 3.7E-9 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 PRINTS PR01035 Tetracycline resistance protein signature 287 308 3.7E-9 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 PRINTS PR01035 Tetracycline resistance protein signature 143 165 3.7E-9 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 PRINTS PR01035 Tetracycline resistance protein signature 113 134 3.7E-9 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 PRINTS PR01035 Tetracycline resistance protein signature 348 371 3.7E-9 T 06-07-2017 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 Gene3D G3DSA:1.20.1250.20 220 402 2.9E-29 T 06-07-2017 CAL12_RS22920 bfd5c3b5abd7edaa6229871277ac96e1 410 Gene3D G3DSA:1.20.1250.20 12 195 7.3E-33 T 06-07-2017 CAL12_RS11635 85066eba142d1064b41f90e8a21191e5 321 PIRSF PIRSF017082 1 321 7.9E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11635 85066eba142d1064b41f90e8a21191e5 321 SUPERFAMILY SSF53850 112 283 7.31E-11 T 06-07-2017 CAL12_RS11635 85066eba142d1064b41f90e8a21191e5 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 3.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11635 85066eba142d1064b41f90e8a21191e5 321 Gene3D G3DSA:3.40.190.10 124 234 1.1E-6 T 06-07-2017 CAL12_RS14450 310b3807dbfcb6bbe93dd0f15f6f7901 273 Gene3D G3DSA:1.10.3720.10 17 260 2.7E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14450 310b3807dbfcb6bbe93dd0f15f6f7901 273 SUPERFAMILY SSF161098 10 259 2.15E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14450 310b3807dbfcb6bbe93dd0f15f6f7901 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 260 4.6E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 SUPERFAMILY SSF51905 147 317 1.78E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Gene3D G3DSA:3.50.50.60 107 236 2.6E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Pfam PF14759 Reductase C-terminal 328 414 1.9E-19 T 06-07-2017 IPR028202 Reductase, C-terminal CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 3.7E-18 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 3.7E-18 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.7E-18 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 3.7E-18 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Gene3D G3DSA:3.50.50.60 4 106 1.9E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 309 3.4E-55 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 SUPERFAMILY SSF55424 321 420 3.43E-20 T 06-07-2017 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 4.7E-25 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 4.7E-25 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.7E-25 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 4.7E-25 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 4.7E-25 T 06-07-2017 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Gene3D G3DSA:3.50.50.60 237 320 6.1E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 SUPERFAMILY SSF51905 6 188 3.99E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12850 9c589a94544f75e25c5ae638a809e7d9 426 Gene3D G3DSA:3.30.390.30 328 420 9.5E-23 T 06-07-2017 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 Pfam PF03958 Bacterial type II/III secretion system short domain 186 315 1.4E-17 T 06-07-2017 IPR005644 NolW-like CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 TIGRFAM TIGR02516 type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family 273 548 5.8E-80 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 526 545 1.1E-31 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 198 215 1.1E-31 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 436 451 1.1E-31 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 319 339 1.1E-31 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 402 421 1.1E-31 T 06-07-2017 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 CAL12_RS22035 4bd96ac338b479f993650fc92bb74c3b 604 Pfam PF00263 Bacterial type II and III secretion system protein 389 548 1.5E-37 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 Gene3D G3DSA:1.20.120.530 79 217 6.7E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 SMART SM00345 17 75 7.9E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 75 3.0E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 SUPERFAMILY SSF46785 11 79 3.33E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 SUPERFAMILY SSF48008 82 213 1.62E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 Pfam PF07729 FCD domain 85 207 3.1E-24 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 Gene3D G3DSA:1.10.10.10 9 76 2.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20020 db8ccbb7bfa14ecbefad0ab00df99c65 225 SMART SM00895 85 208 4.3E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS27080 88ca1eef35a37e0e655ea7914bdfe21c 290 PIRSF PIRSF015582 1 288 1.2E-83 T 06-07-2017 IPR011206 Citrate lyase beta subunit-like CAL12_RS27080 88ca1eef35a37e0e655ea7914bdfe21c 290 SUPERFAMILY SSF51621 2 234 1.33E-61 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS27080 88ca1eef35a37e0e655ea7914bdfe21c 290 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 5 223 4.5E-48 T 06-07-2017 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CAL12_RS27080 88ca1eef35a37e0e655ea7914bdfe21c 290 Gene3D G3DSA:3.20.20.60 2 234 8.9E-71 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS02565 15b5afcc17da215ee96e91e470674502 326 PIRSF PIRSF017082 1 326 1.7E-66 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02565 15b5afcc17da215ee96e91e470674502 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.3E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02565 15b5afcc17da215ee96e91e470674502 326 SUPERFAMILY SSF53850 116 287 1.85E-5 T 06-07-2017 CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 SMART SM00382 28 215 5.4E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 Pfam PF00005 ABC transporter 19 167 4.0E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 SUPERFAMILY SSF52540 3 237 1.33E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 Gene3D G3DSA:3.40.50.300 2 237 2.3E-80 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 PIRSF PIRSF039085 1 240 2.0E-105 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS00480 0dfc00494abbd9cae47e020b9e0d4ee7 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 Gene3D G3DSA:1.10.287.130 223 278 8.0E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 SMART SM00387 332 443 6.8E-27 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 SMART SM00388 233 291 0.0036 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 Pfam PF00672 HAMP domain 162 228 9.9E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 7.3E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 382 7.3E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 396 7.3E-10 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 SUPERFAMILY SSF47384 217 291 8.63E-9 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 Gene3D G3DSA:3.30.565.10 279 439 1.2E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 SMART SM00304 180 232 7.8E-7 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 439 7.9E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS04770 f45d7d34f236907fc451e9457b434272 443 SUPERFAMILY SSF55874 296 439 1.02E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS07590 01b1230c8cea1aec29c04bb6e7e502ea 285 Pfam PF02673 Bacitracin resistance protein BacA 11 277 4.0E-77 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAL12_RS07590 01b1230c8cea1aec29c04bb6e7e502ea 285 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 282 17.647 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAL12_RS07590 01b1230c8cea1aec29c04bb6e7e502ea 285 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 11 275 1.5E-67 T 06-07-2017 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CAL12_RS15245 9d7241a1feac900595bfcaa6110c2f43 128 Pfam PF01042 Endoribonuclease L-PSP 9 127 8.4E-39 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS15245 9d7241a1feac900595bfcaa6110c2f43 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 1.0E-44 T 06-07-2017 IPR006056 RidA family CAL12_RS15245 9d7241a1feac900595bfcaa6110c2f43 128 SUPERFAMILY SSF55298 1 128 5.18E-41 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS15245 9d7241a1feac900595bfcaa6110c2f43 128 Gene3D G3DSA:3.30.1330.40 4 127 2.4E-42 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS12530 521628e6fb533b52fef19d216f7bb93c 513 Gene3D G3DSA:1.20.1270.130 161 241 5.5E-6 T 06-07-2017 CAL12_RS12530 521628e6fb533b52fef19d216f7bb93c 513 Gene3D G3DSA:1.20.58.360 246 304 1.7E-21 T 06-07-2017 CAL12_RS12530 521628e6fb533b52fef19d216f7bb93c 513 Gene3D G3DSA:1.20.58.360 348 410 1.7E-21 T 06-07-2017 CAL12_RS12530 521628e6fb533b52fef19d216f7bb93c 513 Pfam PF14496 C-terminal novel E3 ligase, LRR-interacting 174 410 1.2E-30 T 06-07-2017 IPR029487 Novel E3 ligase domain GO:0004842|GO:0016567 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 4 333 4.0E-101 T 06-07-2017 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 PIRSF PIRSF001220 4 335 8.6E-84 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 PIRSF PIRSF500176 7 334 6.0E-77 T 06-07-2017 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 SUPERFAMILY SSF53774 8 333 3.01E-92 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 Pfam PF00710 Asparaginase, N-terminal 10 191 8.2E-54 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 12 20 - T 06-07-2017 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 PRINTS PR00139 Asparaginase/glutaminase family signature 10 21 1.7E-22 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 PRINTS PR00139 Asparaginase/glutaminase family signature 89 107 1.7E-22 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 PRINTS PR00139 Asparaginase/glutaminase family signature 269 287 1.7E-22 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 SMART SM00870 9 329 8.5E-119 T 06-07-2017 IPR006034 Asparaginase/glutaminase GO:0006520 Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 Gene3D G3DSA:3.40.50.40 223 333 4.1E-33 T 06-07-2017 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 Gene3D G3DSA:3.40.50.1170 7 200 1.5E-62 T 06-07-2017 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CAL12_RS27830 78c6e5ebbb65cac0635f0f3ebb5b1d38 335 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 90 100 - T 06-07-2017 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CAL12_RS09165 6b220cc0266d8400b6386db210d9688d 200 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 8.3E-6 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS09165 6b220cc0266d8400b6386db210d9688d 200 SUPERFAMILY SSF54523 40 200 1.46E-16 T 06-07-2017 CAL12_RS09165 6b220cc0266d8400b6386db210d9688d 200 Pfam PF08805 PilS N terminal 111 199 1.6E-8 T 06-07-2017 IPR014911 Type 4 secretion system, PilS, N-terminal CAL12_RS09165 6b220cc0266d8400b6386db210d9688d 200 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS09165 6b220cc0266d8400b6386db210d9688d 200 Gene3D G3DSA:3.30.700.10 12 80 4.4E-4 T 06-07-2017 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 Gene3D G3DSA:1.10.10.10 1 86 2.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 SUPERFAMILY SSF53850 95 295 1.71E-33 T 06-07-2017 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.3E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 Gene3D G3DSA:3.40.190.10 96 186 6.3E-21 T 06-07-2017 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 SUPERFAMILY SSF46785 1 87 9.98E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 Gene3D G3DSA:3.40.190.10 187 260 2.0E-6 T 06-07-2017 CAL12_RS05960 955e1b1066e945039f8c9843c9f85e03 303 Pfam PF03466 LysR substrate binding domain 95 291 3.3E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03930 84a322bf5b4592c30cb2098cb330e514 205 SUPERFAMILY SSF52499 6 189 8.77E-40 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS03930 84a322bf5b4592c30cb2098cb330e514 205 Gene3D G3DSA:3.40.50.850 7 188 1.8E-35 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS03930 84a322bf5b4592c30cb2098cb330e514 205 Pfam PF00857 Isochorismatase family 15 164 5.5E-22 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 505 3.2E-128 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 Pfam PF07690 Major Facilitator Superfamily 25 421 6.5E-52 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 Gene3D G3DSA:1.20.1250.20 18 202 4.5E-36 T 06-07-2017 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 Gene3D G3DSA:1.20.1250.20 496 518 2.5E-15 T 06-07-2017 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 Gene3D G3DSA:1.20.1250.20 274 437 2.5E-15 T 06-07-2017 CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 SUPERFAMILY SSF103473 491 516 7.19E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 SUPERFAMILY SSF103473 6 203 7.19E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS04255 7dddc16e7c2cfe60b2cc7b0afcd14bf1 526 SUPERFAMILY SSF103473 260 431 7.19E-66 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS25450 de7529fb8014d6af339decf74546772b 155 Gene3D G3DSA:1.10.260.40 4 67 6.1E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25450 de7529fb8014d6af339decf74546772b 155 SMART SM00530 7 61 1.7E-13 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS25450 de7529fb8014d6af339decf74546772b 155 Pfam PF01381 Helix-turn-helix 8 61 9.6E-12 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS25450 de7529fb8014d6af339decf74546772b 155 SUPERFAMILY SSF47413 4 62 6.97E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS18850 081f1abf8f795108b1800894c3feaf21 298 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 180 289 6.4E-13 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAL12_RS18850 081f1abf8f795108b1800894c3feaf21 298 SMART SM00702 100 289 1.7E-33 T 06-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 Pfam PF03023 MviN-like protein 28 473 3.3E-130 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 415 432 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 265 291 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 33 52 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 159 180 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 52 68 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 135 159 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PRINTS PR01806 Virulence factor MviN signature 363 382 5.0E-79 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 508 7.0E-140 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS17470 ee0043511608d278fad57fa3c96670c6 525 PIRSF PIRSF002869 1 518 1.7E-153 T 06-07-2017 IPR004268 Peptidoglycan biosynthesis protein MurJ CAL12_RS02690 3e632fbfee1d0fd3533ae19881de1c8d 153 SUPERFAMILY SSF82784 1 138 1.13E-35 T 06-07-2017 IPR003718 OsmC/Ohr family CAL12_RS02690 3e632fbfee1d0fd3533ae19881de1c8d 153 Gene3D G3DSA:3.30.300.20 41 138 7.6E-40 T 06-07-2017 IPR015946 K homology domain-like, alpha/beta CAL12_RS02690 3e632fbfee1d0fd3533ae19881de1c8d 153 Pfam PF02566 OsmC-like protein 35 132 4.3E-16 T 06-07-2017 IPR003718 OsmC/Ohr family CAL12_RS02690 3e632fbfee1d0fd3533ae19881de1c8d 153 Gene3D G3DSA:2.20.25.10 1 36 1.3E-10 T 06-07-2017 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Gene3D G3DSA:1.10.10.10 4 85 5.2E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Gene3D G3DSA:3.40.190.10 273 301 9.7E-25 T 06-07-2017 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Gene3D G3DSA:3.40.190.10 91 171 9.7E-25 T 06-07-2017 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Gene3D G3DSA:3.40.190.10 172 267 1.2E-29 T 06-07-2017 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 SUPERFAMILY SSF46785 5 83 1.68E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 SUPERFAMILY SSF53850 91 296 7.06E-40 T 06-07-2017 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.5E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03475 5be56d0b677b06395f0d70444280b1a4 312 Pfam PF03466 LysR substrate binding domain 96 296 3.5E-25 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 2.2E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 Gene3D G3DSA:1.10.10.10 2 84 1.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 Pfam PF03466 LysR substrate binding domain 95 293 2.9E-29 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 SUPERFAMILY SSF53850 96 293 9.93E-29 T 06-07-2017 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 SUPERFAMILY SSF46785 3 85 6.35E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.4E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 Gene3D G3DSA:3.40.190.10 196 263 2.4E-7 T 06-07-2017 CAL12_RS03440 2100a7d4e261f8522361ea20b596d7e4 295 Gene3D G3DSA:3.40.190.10 95 195 3.3E-15 T 06-07-2017 CAL12_RS17115 12bedc37ac9cfd436dc55c58cc265633 566 Pfam PF01368 DHH family 77 206 1.1E-9 T 06-07-2017 IPR001667 DDH domain CAL12_RS17115 12bedc37ac9cfd436dc55c58cc265633 566 SUPERFAMILY SSF64182 50 464 6.15E-107 T 06-07-2017 CAL12_RS17115 12bedc37ac9cfd436dc55c58cc265633 566 Pfam PF02272 DHHA1 domain 382 445 6.2E-10 T 06-07-2017 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CAL12_RS17115 12bedc37ac9cfd436dc55c58cc265633 566 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 25 563 2.5E-136 T 06-07-2017 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 CAL12_RS15485 ed6494763cdd7b20fa31ec00c3fbace9 173 Gene3D G3DSA:1.10.10.10 56 132 2.8E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15485 ed6494763cdd7b20fa31ec00c3fbace9 173 SUPERFAMILY SSF46785 28 137 6.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15485 ed6494763cdd7b20fa31ec00c3fbace9 173 PIRSF PIRSF036158 2 173 1.5E-75 T 06-07-2017 IPR014601 Transcriptional regulator with MarR-type HTH domain CAL12_RS15485 ed6494763cdd7b20fa31ec00c3fbace9 173 Pfam PF13463 Winged helix DNA-binding domain 55 120 3.6E-21 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS21810 12f7280d9079e197f5d584a96c21b0f9 193 Pfam PF04264 YceI-like domain 27 181 1.2E-31 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAL12_RS21810 12f7280d9079e197f5d584a96c21b0f9 193 SMART SM00867 26 191 5.9E-53 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAL12_RS21810 12f7280d9079e197f5d584a96c21b0f9 193 Gene3D G3DSA:2.40.128.110 25 193 2.2E-43 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAL12_RS21810 12f7280d9079e197f5d584a96c21b0f9 193 SUPERFAMILY SSF101874 26 191 1.23E-43 T 06-07-2017 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 Gene3D G3DSA:1.10.230.10 281 310 1.7E-5 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 PRINTS PR00143 Citrate synthase signature 234 262 2.7E-11 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 PRINTS PR00143 Citrate synthase signature 212 227 2.7E-11 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 PRINTS PR00143 Citrate synthase signature 286 306 2.7E-11 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 Pfam PF12728 Helix-turn-helix domain 4 55 2.6E-8 T 06-07-2017 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 SUPERFAMILY SSF48256 30 393 8.77E-68 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 Gene3D G3DSA:1.10.10.10 4 58 7.6E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 Gene3D G3DSA:1.10.580.10 74 280 6.2E-35 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS04520 bd768e1246880e31bd929e0988624fbf 431 Pfam PF00285 Citrate synthase, C-terminal domain 71 384 2.6E-58 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 SUPERFAMILY SSF47203 286 460 2.09E-44 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 32 1.0E-9 T 06-07-2017 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Gene3D G3DSA:1.20.140.10 282 464 1.7E-51 T 06-07-2017 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 602 7.5E-22 T 06-07-2017 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 SUPERFAMILY SSF56645 38 267 6.28E-55 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Gene3D G3DSA:1.10.540.10 38 157 1.8E-14 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 266 2.0E-16 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 453 1.2E-26 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 155 8.9E-11 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS18860 b148668a9b77ae44abec4fb8fc4b3c66 614 Gene3D G3DSA:2.40.110.10 160 267 3.2E-26 T 06-07-2017 CAL12_RS14335 d4a8d3d6024169203e4e138ec6327085 219 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 190 4.3E-78 T 06-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CAL12_RS14335 d4a8d3d6024169203e4e138ec6327085 219 SUPERFAMILY SSF46626 21 202 2.33E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14335 d4a8d3d6024169203e4e138ec6327085 219 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 184 8.5E-79 T 06-07-2017 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO CAL12_RS14335 d4a8d3d6024169203e4e138ec6327085 219 Gene3D G3DSA:1.10.760.10 22 203 6.7E-35 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 SMART SM01329 7 356 1.2E-175 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 8 353 2.9E-85 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 Gene3D G3DSA:3.40.718.10 5 351 2.6E-117 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 245 264 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 SUPERFAMILY SSF53659 4 360 3.46E-114 T 06-07-2017 CAL12_RS14640 79d7234daceaf3bdffb0dc3be2061eac 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 359 4.1E-159 T 06-07-2017 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CAL12_RS08560 be81c4615c6cc9d9e10cb668d80654f0 290 Gene3D G3DSA:3.40.50.720 11 224 1.4E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08560 be81c4615c6cc9d9e10cb668d80654f0 290 Pfam PF13460 NAD(P)H-binding 20 173 3.2E-12 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08560 be81c4615c6cc9d9e10cb668d80654f0 290 SUPERFAMILY SSF51735 13 286 3.17E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Pfam PF00579 tRNA synthetases class I (W and Y) 45 328 1.8E-72 T 06-07-2017 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Gene3D G3DSA:3.10.290.10 340 407 3.8E-24 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Gene3D G3DSA:3.40.50.620 19 239 1.1E-78 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 58 80 4.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 4.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 4.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 4.3E-25 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Pfam PF01479 S4 domain 349 391 3.1E-8 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Gene3D G3DSA:1.10.240.10 240 339 2.1E-36 T 06-07-2017 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 SUPERFAMILY SSF55174 310 406 2.22E-19 T 06-07-2017 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 SMART SM00363 347 408 7.8E-4 T 06-07-2017 IPR002942 RNA-binding S4 domain GO:0003723 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 10 407 47.777 T 06-07-2017 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 64 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 SUPERFAMILY SSF52374 19 328 8.67E-89 T 06-07-2017 CAL12_RS24715 46ee23dde957283e3573dea3c9865faa 409 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 14 406 1.2E-119 T 06-07-2017 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 Pfam PF00303 Thymidylate synthase 3 264 1.9E-121 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.323 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 06-07-2017 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 SUPERFAMILY SSF55831 2 264 5.23E-128 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 Gene3D G3DSA:3.30.572.10 1 264 1.2E-130 T 06-07-2017 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 2.3E-47 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 2.3E-47 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.3E-47 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 2.3E-47 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 2.3E-47 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 84 2.1E-39 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS02685 ff0621a31948f6043c65c9afe632ff85 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 264 5.8E-95 T 06-07-2017 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-113510|Reactome: R-HSA-500753|Reactome: R-HSA-69205 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 SMART SM01092 232 330 5.2E-27 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 SUPERFAMILY SSF56176 4 225 1.09E-59 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 233 329 4.2E-18 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Gene3D G3DSA:3.30.465.10 62 119 3.7E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Gene3D G3DSA:3.30.465.10 163 225 3.7E-36 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Gene3D G3DSA:3.30.390.50 230 333 5.9E-35 T 06-07-2017 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 SUPERFAMILY SSF55447 230 331 7.2E-29 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 225 1.3E-49 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS24340 2487e83d1122c4390aaf85448eb2ab05 334 Gene3D G3DSA:3.30.43.10 1 57 9.1E-17 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS10760 1b980bf8b59288320d4b9c157b2d3cee 249 Gene3D G3DSA:1.10.3720.10 12 211 1.9E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10760 1b980bf8b59288320d4b9c157b2d3cee 249 SUPERFAMILY SSF161098 14 202 3.79E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10760 1b980bf8b59288320d4b9c157b2d3cee 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 208 3.9E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10760 1b980bf8b59288320d4b9c157b2d3cee 249 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.4E-30 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS14945 a54025d00696e0e8bc987bc0496255a5 174 SMART SM00972 113 171 4.4E-21 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS14945 a54025d00696e0e8bc987bc0496255a5 174 Pfam PF05229 Spore Coat Protein U domain 34 171 2.0E-34 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS15535 9916cc6631cf221264816e8cdd772721 283 Gene3D G3DSA:1.10.3720.10 4 272 5.6E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15535 9916cc6631cf221264816e8cdd772721 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 278 3.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15535 9916cc6631cf221264816e8cdd772721 283 SUPERFAMILY SSF161098 4 279 1.59E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08005 9e298034a36b30bba33d271c0935c829 143 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS08005 9e298034a36b30bba33d271c0935c829 143 Gene3D G3DSA:3.90.79.10 3 127 9.2E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS08005 9e298034a36b30bba33d271c0935c829 143 Pfam PF00293 NUDIX domain 5 130 1.8E-14 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS08005 9e298034a36b30bba33d271c0935c829 143 PIRSF PIRSF037599 1 142 6.8E-47 T 06-07-2017 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 CAL12_RS08005 9e298034a36b30bba33d271c0935c829 143 SUPERFAMILY SSF55811 3 134 2.03E-25 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS18605 b788c93cc3c76d2191d28afb1ded7efa 523 Pfam PF08666 SAF domain 22 88 1.5E-7 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS18605 b788c93cc3c76d2191d28afb1ded7efa 523 SMART SM00858 22 92 3.3E-9 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS18605 b788c93cc3c76d2191d28afb1ded7efa 523 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 119 521 5.2E-143 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAL12_RS18605 b788c93cc3c76d2191d28afb1ded7efa 523 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 14 523 2.9E-278 T 06-07-2017 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 Gene3D G3DSA:3.40.718.10 147 281 2.0E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 Gene3D G3DSA:3.40.718.10 340 363 2.0E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 Gene3D G3DSA:3.40.718.10 539 645 2.0E-34 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 SUPERFAMILY SSF53659 4 741 0.0 T 06-07-2017 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 Pfam PF03971 Monomeric isocitrate dehydrogenase 6 738 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 741 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAL12_RS01480 d7d77b602976995a3ea1eec4748b1711 743 PIRSF PIRSF009407 1 742 0.0 T 06-07-2017 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CAL12_RS25585 81491e7d85d7efb987741524393141c4 233 Pfam PF02036 SCP-2 sterol transfer family 18 125 7.0E-7 T 06-07-2017 IPR003033 SCP2 sterol-binding domain CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Gene3D G3DSA:1.20.1600.10 378 492 1.4E-107 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Gene3D G3DSA:1.20.1600.10 76 114 1.4E-107 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Gene3D G3DSA:1.20.1600.10 168 340 1.4E-107 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Pfam PF02321 Outer membrane efflux protein 88 280 5.2E-26 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Pfam PF02321 Outer membrane efflux protein 309 489 5.1E-29 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 491 1.4E-125 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Gene3D G3DSA:2.20.200.10 124 167 1.6E-20 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 Gene3D G3DSA:2.20.200.10 341 376 1.6E-20 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 SUPERFAMILY SSF56954 79 494 1.7E-118 T 06-07-2017 CAL12_RS21255 12ef4ee5dd7661d64228f907e634e091 510 SUPERFAMILY SSF56954 1 36 1.7E-118 T 06-07-2017 CAL12_RS27335 b66a630228aa4d83700a2abec09d06de 351 SUPERFAMILY SSF53067 11 143 2.59E-10 T 06-07-2017 CAL12_RS27335 b66a630228aa4d83700a2abec09d06de 351 Pfam PF12693 GspL periplasmic domain 184 295 2.3E-19 T 06-07-2017 IPR025691 GspL periplasmic domain CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Gene3D G3DSA:3.40.50.620 13 196 1.2E-130 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Gene3D G3DSA:3.40.50.620 413 657 1.2E-130 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 SUPERFAMILY SSF50677 200 410 4.4E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 SUPERFAMILY SSF47323 673 943 1.87E-67 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Pfam PF08264 Anticodon-binding domain of tRNA 706 867 1.5E-24 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Gene3D G3DSA:1.10.730.10 663 801 2.7E-38 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Pfam PF06827 Zinc finger found in FPG and IleRS 915 941 5.5E-5 T 06-07-2017 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 869 5.2E-260 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 SUPERFAMILY SSF52374 1 198 4.22E-130 T 06-07-2017 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 SUPERFAMILY SSF52374 410 670 4.22E-130 T 06-07-2017 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Gene3D G3DSA:3.90.740.10 203 396 1.5E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 233 256 8.2E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 8.2E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 539 552 8.2E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 8.2E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 582 591 8.2E-32 T 06-07-2017 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 662 2.5E-210 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS17295 a09e7860f3cf84622ad5e212f0828ed9 953 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 944 20.475 T 06-07-2017 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 277 1.5E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 582 620 7.1E-9 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 SUPERFAMILY SSF52540 8 264 5.67E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 SUPERFAMILY SSF52540 352 602 1.17E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 SMART SM00382 388 580 2.3E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 SMART SM00382 37 242 3.1E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Pfam PF00005 ABC transporter 380 529 3.2E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Pfam PF00005 ABC transporter 29 192 1.1E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Gene3D G3DSA:3.40.50.300 351 604 5.6E-79 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23310 ad7009b7bb7968f8fa4f05a20caa416a 658 Gene3D G3DSA:3.40.50.300 8 266 4.3E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 Pfam PF12146 Serine aminopeptidase, S33 103 312 1.7E-6 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 Gene3D G3DSA:3.40.50.1820 99 211 1.1E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 Gene3D G3DSA:3.40.50.1820 290 340 1.1E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 PIRSF PIRSF005211 1 365 1.6E-117 T 06-07-2017 IPR012020 AB hydrolase 4 family CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 SUPERFAMILY SSF53474 92 345 1.97E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05685 5492de32cf9df979c05a3800195a540e 365 SUPERFAMILY SSF53474 32 59 1.97E-32 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS26430 c41e37e253b5c6ca099a8406bed592c7 294 SMART SM00382 68 269 4.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26430 c41e37e253b5c6ca099a8406bed592c7 294 Gene3D G3DSA:3.40.50.300 42 291 1.9E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26430 c41e37e253b5c6ca099a8406bed592c7 294 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 269 291 3.3E-8 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS26430 c41e37e253b5c6ca099a8406bed592c7 294 SUPERFAMILY SSF52540 43 291 5.93E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26430 c41e37e253b5c6ca099a8406bed592c7 294 Pfam PF00005 ABC transporter 59 220 3.8E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 Gene3D G3DSA:3.40.309.10 267 455 4.0E-62 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 Gene3D G3DSA:3.40.605.10 8 266 1.0E-89 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 Pfam PF00171 Aldehyde dehydrogenase family 21 482 1.3E-160 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 SUPERFAMILY SSF53720 10 484 2.09E-148 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS26015 966a19ab296a8ca0abaf6aa71904db03 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS18685 1a33eb18675e72abe0d43fe49a1fb6e0 326 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 23 312 4.4E-160 T 06-07-2017 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CAL12_RS18685 1a33eb18675e72abe0d43fe49a1fb6e0 326 Pfam PF05138 Phenylacetic acid catabolic protein 33 308 2.2E-103 T 06-07-2017 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CAL12_RS18685 1a33eb18675e72abe0d43fe49a1fb6e0 326 SUPERFAMILY SSF47240 43 286 4.19E-81 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS18685 1a33eb18675e72abe0d43fe49a1fb6e0 326 Gene3D G3DSA:1.20.1260.10 33 288 3.3E-99 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS07615 55f0de59b78ac83b15e505ff64f53668 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 177 2.2E-13 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS07615 55f0de59b78ac83b15e505ff64f53668 212 SMART SM00478 55 208 3.8E-18 T 06-07-2017 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CAL12_RS07615 55f0de59b78ac83b15e505ff64f53668 212 Gene3D G3DSA:1.10.1670.10 156 208 7.4E-15 T 06-07-2017 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CAL12_RS07615 55f0de59b78ac83b15e505ff64f53668 212 Gene3D G3DSA:1.10.340.30 46 155 5.7E-32 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS07615 55f0de59b78ac83b15e505ff64f53668 212 SUPERFAMILY SSF48150 35 206 2.44E-41 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 3 147 6.4E-33 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 SUPERFAMILY SSF81330 13 141 2.35E-29 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 96 104 2.6E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 105 114 2.6E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 2.6E-7 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 145 2.1E-39 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS00765 035ed40481186eab6961c0bf1e4d88e7 152 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 148 23.196 T 06-07-2017 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CAL12_RS04220 ae449d8623e9870abd711e58186c0d48 412 PIRSF PIRSF031773 2 411 1.9E-83 T 06-07-2017 IPR005891 DevC protein CAL12_RS04220 ae449d8623e9870abd711e58186c0d48 412 Pfam PF02687 FtsX-like permease family 295 407 4.2E-7 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS22570 7d5089f211d7f8a11721a15ee78fceb1 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 2.6E-153 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.9E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 Gene3D G3DSA:3.40.190.10 177 258 2.1E-18 T 06-07-2017 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 Gene3D G3DSA:1.10.10.10 3 80 7.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 SUPERFAMILY SSF46785 4 112 1.14E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 Pfam PF03466 LysR substrate binding domain 88 289 4.1E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 Gene3D G3DSA:3.40.190.10 92 176 5.2E-24 T 06-07-2017 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.8E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16630 948657df489a857ca7585925fb1c6407 305 SUPERFAMILY SSF53850 89 293 3.08E-42 T 06-07-2017 CAL12_RS08070 a4188d31dc4352fa0e7ac8c2a366d76f 149 PIRSF PIRSF029477 1 148 5.8E-58 T 06-07-2017 IPR016920 Uncharacterised conserved protein UCP029477 CAL12_RS08070 a4188d31dc4352fa0e7ac8c2a366d76f 149 Pfam PF09537 Domain of unknown function (DUF2383) 5 113 1.5E-36 T 06-07-2017 IPR019052 Domain of unknown function DUF2383 CAL12_RS08070 a4188d31dc4352fa0e7ac8c2a366d76f 149 TIGRFAM TIGR02284 TIGR02284: conserved hypothetical protein 5 142 7.7E-47 T 06-07-2017 IPR011971 Conserved hypothetical protein CHP02284 CAL12_RS08550 d45942aacd0cc6ce6a9aab524e50acad 338 Pfam PF01212 Beta-eliminating lyase 3 284 5.4E-92 T 06-07-2017 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CAL12_RS08550 d45942aacd0cc6ce6a9aab524e50acad 338 Gene3D G3DSA:3.40.640.10 1 246 5.5E-84 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS08550 d45942aacd0cc6ce6a9aab524e50acad 338 Gene3D G3DSA:3.90.1150.10 247 336 1.8E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS08550 d45942aacd0cc6ce6a9aab524e50acad 338 SUPERFAMILY SSF53383 1 335 2.1E-114 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS08550 d45942aacd0cc6ce6a9aab524e50acad 338 PIRSF PIRSF017617 1 338 2.7E-137 T 06-07-2017 IPR023603 Threonine aldolase CAL12_RS07005 82ab72765f2adb5a3c5dd07438a89fb3 179 PIRSF PIRSF030820 4 178 3.7E-47 T 06-07-2017 IPR008318 Uncharacterised conserved protein UCP030820 CAL12_RS07005 82ab72765f2adb5a3c5dd07438a89fb3 179 Pfam PF06073 Bacterial protein of unknown function (DUF934) 65 172 5.6E-33 T 06-07-2017 IPR008318 Uncharacterised conserved protein UCP030820 CAL12_RS18140 de1a81606a3d32ef5c4f98e315b1ab16 315 Pfam PF04909 Amidohydrolase 45 312 4.1E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS18140 de1a81606a3d32ef5c4f98e315b1ab16 315 SUPERFAMILY SSF51556 42 312 2.5E-58 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS18140 de1a81606a3d32ef5c4f98e315b1ab16 315 Gene3D G3DSA:3.20.20.140 27 313 3.9E-76 T 06-07-2017 CAL12_RS15895 e52f67bc375da858bf2e3f4176f8ce44 200 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 197 30.066 T 06-07-2017 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CAL12_RS15895 e52f67bc375da858bf2e3f4176f8ce44 200 SUPERFAMILY SSF52218 1 200 1.55E-52 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS15895 e52f67bc375da858bf2e3f4176f8ce44 200 Pfam PF02525 Flavodoxin-like fold 1 199 7.0E-47 T 06-07-2017 IPR003680 Flavodoxin-like fold CAL12_RS15895 e52f67bc375da858bf2e3f4176f8ce44 200 Gene3D G3DSA:3.40.50.360 1 200 1.2E-61 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 320 408 6.2E-27 T 06-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 416 501 1.6E-23 T 06-07-2017 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 SUPERFAMILY SSF55021 409 502 2.08E-27 T 06-07-2017 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 306 1.3E-80 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 SUPERFAMILY SSF53686 5 355 1.15E-102 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 502 2.1E-251 T 06-07-2017 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 Gene3D G3DSA:3.40.50.1100 69 323 2.2E-85 T 06-07-2017 CAL12_RS25655 ab1e92a4d28c9d39964646e4ce77ce2f 502 Gene3D G3DSA:3.40.1020.10 383 502 1.9E-46 T 06-07-2017 CAL12_RS09650 a2fdad6eb12cae8b2f70a811fceb7dcb 427 Pfam PF00990 Diguanylate cyclase, GGDEF domain 257 414 4.6E-46 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS09650 a2fdad6eb12cae8b2f70a811fceb7dcb 427 SMART SM00267 246 418 2.3E-66 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS09650 a2fdad6eb12cae8b2f70a811fceb7dcb 427 SUPERFAMILY SSF55073 262 419 4.24E-50 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS09650 a2fdad6eb12cae8b2f70a811fceb7dcb 427 Gene3D G3DSA:3.30.70.270 258 423 9.7E-55 T 06-07-2017 CAL12_RS09650 a2fdad6eb12cae8b2f70a811fceb7dcb 427 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 255 417 1.3E-51 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS13215 ab918c8ba108f738a869408f1df9d48c 296 SUPERFAMILY SSF51197 14 290 5.04E-68 T 06-07-2017 CAL12_RS13215 ab918c8ba108f738a869408f1df9d48c 296 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 22 288 1.8E-53 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS13215 ab918c8ba108f738a869408f1df9d48c 296 Gene3D G3DSA:3.60.130.10 12 290 2.1E-68 T 06-07-2017 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 97 351 7.6E-103 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 352 34.932 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 SUPERFAMILY SSF53659 5 74 3.67E-105 T 06-07-2017 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 SUPERFAMILY SSF53659 103 352 3.67E-105 T 06-07-2017 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 348 8.4E-107 T 06-07-2017 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CAL12_RS18250 0b8050319d1a309de6161823c1e341ee 354 Gene3D G3DSA:3.40.718.10 2 352 1.3E-124 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS22485 2efa2a94d0cf05dc141649e5cb123331 92 Gene3D G3DSA:1.10.245.10 10 91 4.2E-32 T 06-07-2017 IPR003121 SWIB/MDM2 domain GO:0005515 CAL12_RS22485 2efa2a94d0cf05dc141649e5cb123331 92 SUPERFAMILY SSF47592 12 91 3.05E-28 T 06-07-2017 IPR003121 SWIB/MDM2 domain GO:0005515 CAL12_RS22485 2efa2a94d0cf05dc141649e5cb123331 92 Pfam PF02201 SWIB/MDM2 domain 19 91 8.2E-29 T 06-07-2017 IPR003121 SWIB/MDM2 domain GO:0005515 CAL12_RS22485 2efa2a94d0cf05dc141649e5cb123331 92 SMART SM00151 17 92 1.2E-32 T 06-07-2017 IPR019835 SWIB domain Reactome: R-HSA-3214858 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 SMART SM00411 8 97 1.2E-43 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 SUPERFAMILY SSF47729 8 99 5.89E-33 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 Pfam PF00216 Bacterial DNA-binding protein 8 96 2.3E-31 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 PRINTS PR01727 Prokaryotic integration host factor signature 47 62 6.8E-14 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 PRINTS PR01727 Prokaryotic integration host factor signature 81 95 6.8E-14 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 PRINTS PR01727 Prokaryotic integration host factor signature 65 78 6.8E-14 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 53 72 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 Gene3D G3DSA:4.10.520.10 7 98 1.2E-36 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 6 102 30.025 T 06-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CAL12_RS09945 3e2673c87f0adeb30ffd7a12da8431ba 109 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 7 100 1.3E-43 T 06-07-2017 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 Gene3D G3DSA:3.40.50.300 5 242 1.3E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 Pfam PF00005 ABC transporter 25 166 6.5E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 SMART SM00382 33 216 3.8E-19 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 Pfam PF08402 TOBE domain 280 355 3.7E-11 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 SUPERFAMILY SSF52540 9 247 1.06E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03200 779ff839cdd06370dfa4bb91138f1983 359 SUPERFAMILY SSF50331 243 355 1.56E-12 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS00085 7ec8754c751dc9f02f556a33cf250293 312 Gene3D G3DSA:3.40.190.10 108 215 1.2E-4 T 06-07-2017 CAL12_RS00085 7ec8754c751dc9f02f556a33cf250293 312 PIRSF PIRSF017082 1 308 6.1E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00085 7ec8754c751dc9f02f556a33cf250293 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 30 304 1.4E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00085 7ec8754c751dc9f02f556a33cf250293 312 SUPERFAMILY SSF53850 96 265 3.46E-12 T 06-07-2017 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Gene3D G3DSA:1.10.220.30 11 69 3.5E-16 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 SUPERFAMILY SSF48029 117 326 1.22E-63 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Pfam PF14842 FliG N-terminal domain 8 103 7.1E-30 T 06-07-2017 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 9 334 5.4E-118 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 SUPERFAMILY SSF48029 9 105 1.33E-20 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Pfam PF14841 FliG middle domain 118 191 1.9E-24 T 06-07-2017 IPR032779 Flagellar motor switch protein FliG, middle domain CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Pfam PF01706 FliG C-terminal domain 220 326 2.4E-39 T 06-07-2017 IPR023087 Flagellar motor switch protein FliG, C-terminal CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PIRSF PIRSF003161 1 335 3.2E-117 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 228 248 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 117 140 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 197 222 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 274 300 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 PRINTS PR00954 Flagellar motor switch protein FliG signature 250 270 6.3E-70 T 06-07-2017 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Gene3D G3DSA:1.10.220.30 75 186 1.0E-27 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAL12_RS12020 74e39c9b78a95622652a20230325b5e8 335 Gene3D G3DSA:1.10.220.30 197 334 1.1E-39 T 06-07-2017 IPR011002 Flagellar motor switch protein FliG, alpha-helical CAL12_RS23375 9a3a7b83b0e8252ec2f9bccee7d4c4ad 323 Gene3D G3DSA:3.40.50.1820 10 318 8.5E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23375 9a3a7b83b0e8252ec2f9bccee7d4c4ad 323 SUPERFAMILY SSF53474 8 318 3.71E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23375 9a3a7b83b0e8252ec2f9bccee7d4c4ad 323 Pfam PF12697 Alpha/beta hydrolase family 38 313 2.1E-14 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Gene3D G3DSA:3.20.20.140 349 408 3.1E-110 T 06-07-2017 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Gene3D G3DSA:3.20.20.140 67 290 3.1E-110 T 06-07-2017 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Gene3D G3DSA:2.30.40.10 409 473 8.8E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 SUPERFAMILY SSF51338 432 483 7.12E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 SUPERFAMILY SSF51338 10 64 7.12E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Pfam PF07969 Amidohydrolase family 51 258 8.9E-23 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Pfam PF07969 Amidohydrolase family 355 466 4.8E-15 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Gene3D G3DSA:2.30.40.10 10 66 8.5E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 Gene3D G3DSA:3.30.1490.130 293 348 5.4E-20 T 06-07-2017 IPR023100 D-aminoacylase, insert domain GO:0016811 CAL12_RS20650 1067b348ccb621a28e049acea8ab3936 491 SUPERFAMILY SSF51556 63 424 8.33E-80 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS17885 a4479155260b37ca000a5512fb02556a 131 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 104 23.194 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAL12_RS17885 a4479155260b37ca000a5512fb02556a 131 Pfam PF02410 Ribosomal silencing factor during starvation 9 103 2.2E-25 T 06-07-2017 CAL12_RS17885 a4479155260b37ca000a5512fb02556a 131 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 103 2.8E-32 T 06-07-2017 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CAL12_RS17885 a4479155260b37ca000a5512fb02556a 131 Gene3D G3DSA:3.30.460.10 2 106 1.8E-34 T 06-07-2017 CAL12_RS17885 a4479155260b37ca000a5512fb02556a 131 SUPERFAMILY SSF81301 1 108 1.37E-33 T 06-07-2017 CAL12_RS03875 a4d63b4722743686273462bcda0ec1b7 131 Gene3D G3DSA:3.30.1330.40 12 125 7.4E-21 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS03875 a4d63b4722743686273462bcda0ec1b7 131 Pfam PF01042 Endoribonuclease L-PSP 23 124 1.1E-12 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS03875 a4d63b4722743686273462bcda0ec1b7 131 SUPERFAMILY SSF55298 5 125 5.81E-22 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 145 177 7.7E-5 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 190 222 150.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 322 353 2.3 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 280 312 0.014 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 67 98 12.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SMART SM00564 106 137 43.0 T 06-07-2017 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 12 382 1.7E-124 T 06-07-2017 IPR017687 Outer membrane protein assembly factor BamB CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 SUPERFAMILY SSF50998 30 374 2.69E-72 T 06-07-2017 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 Gene3D G3DSA:2.140.10.10 8 382 9.1E-59 T 06-07-2017 IPR027295 Quinoprotein alcohol dehydrogenase-like domain CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 5 384 36.843 T 06-07-2017 IPR017687 Outer membrane protein assembly factor BamB CAL12_RS09235 9eac7826944f9cc874151452c0a77ef3 385 Pfam PF13360 PQQ-like domain 80 311 3.7E-54 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAL12_RS18760 0aad378f683228554ab25907e4e28f7b 345 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 37 341 1.3E-127 T 06-07-2017 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 CAL12_RS18760 0aad378f683228554ab25907e4e28f7b 345 Gene3D G3DSA:3.40.190.10 52 143 5.8E-9 T 06-07-2017 CAL12_RS18760 0aad378f683228554ab25907e4e28f7b 345 Gene3D G3DSA:3.40.190.10 144 294 3.0E-69 T 06-07-2017 CAL12_RS18760 0aad378f683228554ab25907e4e28f7b 345 SUPERFAMILY SSF53850 40 342 3.69E-74 T 06-07-2017 CAL12_RS18760 0aad378f683228554ab25907e4e28f7b 345 Pfam PF13531 Bacterial extracellular solute-binding protein 52 296 6.8E-42 T 06-07-2017 CAL12_RS03660 babd47436dca56cf74f1c6c539a37d98 194 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 8 188 2.3E-72 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS03660 babd47436dca56cf74f1c6c539a37d98 194 Gene3D G3DSA:3.40.50.1950 8 190 7.8E-77 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS03660 babd47436dca56cf74f1c6c539a37d98 194 Pfam PF02441 Flavoprotein 8 131 1.1E-23 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS03660 babd47436dca56cf74f1c6c539a37d98 194 SUPERFAMILY SSF52507 8 190 2.49E-60 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS03660 babd47436dca56cf74f1c6c539a37d98 194 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 7 190 36.225 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 Gene3D G3DSA:3.30.465.10 200 284 2.1E-26 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 Gene3D G3DSA:3.10.580.10 60 199 4.9E-18 T 06-07-2017 CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 Pfam PF03471 Transporter associated domain 210 284 3.6E-19 T 06-07-2017 IPR005170 Transporter-associated domain CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 SMART SM01091 207 285 1.9E-26 T 06-07-2017 IPR005170 Transporter-associated domain CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 SUPERFAMILY SSF56176 206 292 1.31E-22 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 SUPERFAMILY SSF54631 69 206 5.94E-30 T 06-07-2017 CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 Pfam PF00571 CBS domain 142 191 6.0E-5 T 06-07-2017 IPR000644 CBS domain CAL12_RS04860 923a1922ec9e53608989bde040e538ff 297 Pfam PF00571 CBS domain 95 131 1.8E-4 T 06-07-2017 IPR000644 CBS domain CAL12_RS22270 f758016b2f2fbd3afdfd070e6d226cda 543 Pfam PF02470 MlaD protein 171 231 6.8E-9 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS22270 f758016b2f2fbd3afdfd070e6d226cda 543 Pfam PF02470 MlaD protein 301 405 6.4E-13 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS22270 f758016b2f2fbd3afdfd070e6d226cda 543 Pfam PF02470 MlaD protein 56 147 2.2E-10 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS16705 c7fd8f6ffc3c98f1e0a6887958d2f663 182 SUPERFAMILY SSF55729 2 168 1.03E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS16705 c7fd8f6ffc3c98f1e0a6887958d2f663 182 Pfam PF13673 Acetyltransferase (GNAT) domain 41 146 5.8E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS16705 c7fd8f6ffc3c98f1e0a6887958d2f663 182 Gene3D G3DSA:3.40.630.30 4 154 1.0E-24 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 SUPERFAMILY SSF53474 13 266 4.16E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 2.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 2.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 2.4E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 Pfam PF00561 alpha/beta hydrolase fold 27 143 2.1E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS22740 47e510c098ff8988beb21635f2da58c2 267 Gene3D G3DSA:3.40.50.1820 15 266 1.7E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 SUPERFAMILY SSF51126 1 70 7.85E-5 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 Pfam PF12951 Passenger-associated-transport-repeat 7 36 3.9E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 Pfam PF12951 Passenger-associated-transport-repeat 99 123 4.1E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 Gene3D G3DSA:2.160.20.20 1 122 7.3E-12 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 SUPERFAMILY SSF51126 40 122 8.95E-6 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 7 37 5.6E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23690 55cdc96641385177fab37fb024af42d5 123 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 98 123 2.3E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 Gene3D G3DSA:3.10.20.30 10 83 3.9E-24 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 SUPERFAMILY SSF47741 94 166 1.31E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 Pfam PF01799 [2Fe-2S] binding domain 82 155 1.4E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 63 6.0E-4 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 SUPERFAMILY SSF54292 11 86 5.79E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS15830 41ce94989fc2e53c327ce5431021f4c4 190 Gene3D G3DSA:1.10.150.120 84 176 1.5E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 PIRSF PIRSF000447 1 409 1.5E-185 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 06-07-2017 IPR018201 Beta-ketoacyl synthase, active site CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 406 5.3E-198 T 06-07-2017 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 SUPERFAMILY SSF53901 213 408 6.04E-68 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 SMART SM00825 Beta-ketoacyl synthase 5 409 3.8E-14 T 06-07-2017 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 366 4.4E-33 T 06-07-2017 IPR014031 Beta-ketoacyl synthase, C-terminal CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 Gene3D G3DSA:3.40.47.10 2 256 2.5E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 Gene3D G3DSA:3.40.47.10 262 408 1.0E-56 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 7.8E-64 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAL12_RS08375 97ab94c409b88f6be217176518033f69 409 SUPERFAMILY SSF53901 2 251 3.1E-82 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 5 956 25.511 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 SUPERFAMILY SSF53383 14 436 1.14E-107 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 Gene3D G3DSA:3.40.640.10 81 297 3.7E-18 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 Gene3D G3DSA:3.40.640.10 500 734 1.1E-41 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 Pfam PF02347 Glycine cleavage system P-protein 14 435 2.3E-183 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 Pfam PF02347 Glycine cleavage system P-protein 446 732 5.8E-13 T 06-07-2017 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 14 950 0.0 T 06-07-2017 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 SUPERFAMILY SSF53383 929 951 4.95E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS02660 0b7a4e9cff59ba0284bac16edd1c468b 957 SUPERFAMILY SSF53383 459 886 4.95E-97 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 1.3E-60 T 06-07-2017 CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 Gene3D G3DSA:3.40.50.720 2 247 8.2E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.2E-39 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.1E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS23875 8f3c9cdca94f73489defac96112203eb 248 SUPERFAMILY SSF51735 6 247 8.61E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13775 07b0a0fef4f1cce42acb1b80838750fa 500 Pfam PF00916 Sulfate permease family 26 152 3.3E-17 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAL12_RS13775 07b0a0fef4f1cce42acb1b80838750fa 500 Pfam PF00916 Sulfate permease family 165 354 2.6E-21 T 06-07-2017 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CAL12_RS13775 07b0a0fef4f1cce42acb1b80838750fa 500 Gene3D G3DSA:3.30.750.24 409 484 6.3E-8 T 06-07-2017 IPR002645 STAS domain CAL12_RS13775 07b0a0fef4f1cce42acb1b80838750fa 500 Pfam PF01740 STAS domain 414 485 6.6E-7 T 06-07-2017 IPR002645 STAS domain CAL12_RS13775 07b0a0fef4f1cce42acb1b80838750fa 500 SUPERFAMILY SSF52091 408 485 6.67E-9 T 06-07-2017 IPR002645 STAS domain CAL12_RS19735 ca51076334e67659f281ca572aa7695b 359 SUPERFAMILY SSF89733 12 354 2.88E-104 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS19735 ca51076334e67659f281ca572aa7695b 359 Gene3D G3DSA:1.10.1530.10 13 82 4.0E-23 T 06-07-2017 CAL12_RS19735 ca51076334e67659f281ca572aa7695b 359 Pfam PF02615 Malate/L-lactate dehydrogenase 15 345 3.5E-112 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS19735 ca51076334e67659f281ca572aa7695b 359 Gene3D G3DSA:3.30.1370.60 83 285 4.0E-71 T 06-07-2017 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 Pfam PF00850 Histone deacetylase domain 57 333 2.1E-67 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 PRINTS PR01270 Histone deacetylase superfamily signature 185 200 3.8E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 PRINTS PR01270 Histone deacetylase superfamily signature 271 281 3.8E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 PRINTS PR01270 Histone deacetylase superfamily signature 153 176 3.8E-15 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 SUPERFAMILY SSF52768 2 338 4.8E-87 T 06-07-2017 CAL12_RS03140 976e839a1cb39f67dce6f3ceed596a7f 339 Gene3D G3DSA:3.40.800.20 5 336 2.2E-78 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 Gene3D G3DSA:1.10.10.10 2 63 1.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 SUPERFAMILY SSF53697 94 248 2.67E-17 T 06-07-2017 CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 Gene3D G3DSA:3.40.50.10490 64 259 8.8E-17 T 06-07-2017 CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 SUPERFAMILY SSF46689 2 74 1.65E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 72 2.5E-8 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAL12_RS04010 e81d682058add64e88e1c44e9c34a18b 278 Pfam PF01380 SIS domain 123 244 7.2E-8 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS23480 e9ab17a51434442ae46cb0cd79dea33a 138 Gene3D G3DSA:3.30.1330.40 23 138 5.7E-39 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS23480 e9ab17a51434442ae46cb0cd79dea33a 138 Pfam PF01042 Endoribonuclease L-PSP 26 137 2.7E-25 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS23480 e9ab17a51434442ae46cb0cd79dea33a 138 SUPERFAMILY SSF55298 24 138 2.51E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 SUPERFAMILY SSF51604 146 379 8.12E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 Gene3D G3DSA:3.20.20.120 141 378 3.7E-64 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 Pfam PF13378 Enolase C-terminal domain-like 159 369 7.9E-58 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 SUPERFAMILY SSF54826 1 132 3.23E-26 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 200 231 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 SMART SM00922 154 251 9.2E-24 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 Gene3D G3DSA:3.30.390.10 1 140 2.6E-26 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15020 cc3d0b63cb0dffa44c65802266eb02f0 380 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 129 2.2E-14 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS25260 6461149e95ed075e9dd98f2b39caccda 224 Gene3D G3DSA:3.40.50.300 1 217 3.4E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25260 6461149e95ed075e9dd98f2b39caccda 224 SUPERFAMILY SSF52540 1 218 2.77E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25260 6461149e95ed075e9dd98f2b39caccda 224 SMART SM00382 27 214 3.3E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25260 6461149e95ed075e9dd98f2b39caccda 224 Pfam PF00005 ABC transporter 18 166 1.0E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25260 6461149e95ed075e9dd98f2b39caccda 224 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 Hamap MF_01917 Cardiolipin synthase B [clsB]. 7 413 45.827 T 06-07-2017 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 Pfam PF13091 PLD-like domain 29 141 2.7E-15 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 Pfam PF13091 PLD-like domain 247 364 1.1E-21 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 SUPERFAMILY SSF56024 219 378 8.52E-37 T 06-07-2017 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 Gene3D G3DSA:3.30.870.10 236 398 1.0E-37 T 06-07-2017 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 Gene3D G3DSA:3.30.870.10 9 195 2.0E-41 T 06-07-2017 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 SUPERFAMILY SSF56024 9 184 2.88E-44 T 06-07-2017 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 SMART SM00155 316 342 0.012 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS27050 cc1fcf5a8d91dcd1d5bb0bd3c9843ae5 413 SMART SM00155 116 143 5.3E-5 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Gene3D G3DSA:2.40.50.140 1 106 1.6E-37 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Pfam PF02938 GAD domain 308 406 1.7E-27 T 06-07-2017 IPR029351 GAD domain Reactome: R-HSA-379726 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 SUPERFAMILY SSF55261 291 416 1.39E-42 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 588 5.0E-242 T 06-07-2017 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 Reactome: R-HSA-379726 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Gene3D G3DSA:3.30.1360.30 277 412 3.1E-46 T 06-07-2017 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Pfam PF01336 OB-fold nucleic acid binding domain 18 101 3.6E-17 T 06-07-2017 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 SUPERFAMILY SSF55681 430 591 7.56E-105 T 06-07-2017 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 SUPERFAMILY SSF55681 110 292 7.56E-105 T 06-07-2017 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.4E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 480 496 1.4E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 524 538 1.4E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.4E-26 T 06-07-2017 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 SUPERFAMILY SSF50249 1 104 1.16E-31 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Gene3D G3DSA:3.30.930.10 131 276 2.4E-113 T 06-07-2017 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Gene3D G3DSA:3.30.930.10 413 590 2.4E-113 T 06-07-2017 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 569 36.071 T 06-07-2017 CAL12_RS27060 88dfc3d400806fad909d0499afa265dc 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 564 1.9E-107 T 06-07-2017 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS20525 2f3564ab1778ced11ba3cd569cca290e 265 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 263 1.1E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS20525 2f3564ab1778ced11ba3cd569cca290e 265 Gene3D G3DSA:3.90.226.10 9 262 5.2E-55 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS20525 2f3564ab1778ced11ba3cd569cca290e 265 SUPERFAMILY SSF52096 9 262 6.47E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 Gene3D G3DSA:3.40.190.10 184 266 1.4E-19 T 06-07-2017 CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 Gene3D G3DSA:3.40.190.10 89 183 4.1E-19 T 06-07-2017 CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 Pfam PF03466 LysR substrate binding domain 88 292 4.5E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 SUPERFAMILY SSF46785 1 110 9.54E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 Gene3D G3DSA:1.10.10.10 1 86 3.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 SUPERFAMILY SSF53850 88 299 1.24E-32 T 06-07-2017 CAL12_RS06725 acb58d24ec88a37f389bce05564161b0 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 5.7E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 SUPERFAMILY SSF88946 4 89 7.46E-13 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 Pfam PF08281 Sigma-70, region 4 120 171 5.8E-8 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 Pfam PF04542 Sigma-70 region 2 15 74 2.5E-10 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 SUPERFAMILY SSF88659 111 172 3.71E-10 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 Gene3D G3DSA:1.10.1740.10 3 75 2.5E-12 T 06-07-2017 CAL12_RS23085 9c1e760e2a8c36c9f929a674a8e59a5b 459 Gene3D G3DSA:1.10.10.10 114 173 1.0E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00890 8e877ac9bfbb16861a5c5584b7575ca2 278 SMART SM00382 37 226 4.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00890 8e877ac9bfbb16861a5c5584b7575ca2 278 Gene3D G3DSA:3.40.50.300 8 247 2.4E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00890 8e877ac9bfbb16861a5c5584b7575ca2 278 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS00890 8e877ac9bfbb16861a5c5584b7575ca2 278 Pfam PF00005 ABC transporter 28 177 6.1E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00890 8e877ac9bfbb16861a5c5584b7575ca2 278 SUPERFAMILY SSF52540 12 240 7.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SMART SM01086 669 759 9.1E-33 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Gene3D G3DSA:1.10.8.60 681 758 4.9E-28 T 06-07-2017 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Gene3D G3DSA:3.40.50.300 459 680 4.2E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Gene3D G3DSA:3.40.50.300 185 366 1.3E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SMART SM00382 222 366 4.9E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SMART SM00382 503 652 3.7E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Pfam PF07724 AAA domain (Cdc48 subfamily) 502 663 1.2E-45 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 15 750 0.0 T 06-07-2017 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Gene3D G3DSA:1.10.8.60 367 447 1.4E-28 T 06-07-2017 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SUPERFAMILY SSF52540 453 755 4.04E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Gene3D G3DSA:1.10.1780.10 14 155 4.9E-39 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 318 330 - T 06-07-2017 IPR018368 ClpA/B, conserved site 1 GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 669 749 6.5E-22 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 507 525 2.9E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 578 596 2.9E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 611 625 2.9E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 2.9E-38 T 06-07-2017 IPR001270 ClpA/B family GO:0005524 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SUPERFAMILY SSF81923 14 155 2.45E-54 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 SUPERFAMILY SSF52540 184 432 5.51E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 534 552 - T 06-07-2017 IPR028299 ClpA/B, conserved site 2 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 25 74 9.8E-12 T 06-07-2017 IPR004176 Clp, N-terminal GO:0019538 CAL12_RS17385 ea556f4d4d763514410c4d8ab885ea19 779 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 227 357 7.6E-12 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 SMART SM01008 30 138 8.2E-36 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.90.1170.50 10 135 4.2E-38 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 169 272 2.0E-32 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 SUPERFAMILY SSF54665 12 137 6.67E-37 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 443 609 1.9E-28 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 349 442 3.7E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 610 743 3.7E-57 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 136 168 6.1E-8 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Gene3D G3DSA:3.30.365.10 276 347 6.1E-8 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 30 136 5.4E-23 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 684 4.5E-124 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24335 a355a7d6efdb5cba4c1bd6c31b96f593 743 SUPERFAMILY SSF56003 154 742 6.8E-160 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 SUPERFAMILY SSF55729 649 793 7.55E-23 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 SUPERFAMILY SSF52210 275 433 1.83E-29 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Gene3D G3DSA:3.40.630.30 648 793 7.2E-22 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Gene3D G3DSA:3.40.50.261 268 422 1.1E-10 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Pfam PF13549 ATP-grasp domain 499 609 1.8E-21 T 06-07-2017 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 147 269 4.3E-32 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Pfam PF00583 Acetyltransferase (GNAT) family 719 791 4.1E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 SUPERFAMILY SSF52210 126 269 1.27E-30 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS24795 7dd413349d88126277e4727391cf6cff 813 Gene3D G3DSA:3.40.50.261 117 240 6.0E-19 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 SUPERFAMILY SSF51735 3 237 5.24E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.2E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.2E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.2E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.2E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 188 3.0E-4 T 06-07-2017 CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 Pfam PF00106 short chain dehydrogenase 3 190 6.4E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16440 5dbd1debad6b888a9e30ec9802b09b3a 291 Gene3D G3DSA:3.40.50.720 2 237 1.2E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Gene3D G3DSA:1.20.1600.10 145 317 2.8E-99 T 06-07-2017 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Gene3D G3DSA:1.20.1600.10 52 89 2.8E-99 T 06-07-2017 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Gene3D G3DSA:1.20.1600.10 355 469 2.8E-99 T 06-07-2017 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 9 467 4.3E-118 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Pfam PF02321 Outer membrane efflux protein 63 257 2.5E-21 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Pfam PF02321 Outer membrane efflux protein 286 453 1.3E-22 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 SUPERFAMILY SSF56954 2 469 2.75E-106 T 06-07-2017 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Gene3D G3DSA:2.20.200.10 318 347 4.4E-12 T 06-07-2017 CAL12_RS12565 02ebd1516a5979606c54a6d04adf8051 509 Gene3D G3DSA:2.20.200.10 99 144 4.4E-12 T 06-07-2017 CAL12_RS20155 f04544eb4241c2f92b400be8255872b0 312 Pfam PF10671 Toxin co-regulated pilus biosynthesis protein Q 216 296 4.1E-17 T 06-07-2017 IPR018927 Toxin co-regulated pilus biosynthesis protein Q, C-terminal CAL12_RS20880 d86b7b03722b1dc8c7bce490e8c78a49 397 SUPERFAMILY SSF103473 4 369 6.67E-47 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS20880 d86b7b03722b1dc8c7bce490e8c78a49 397 Gene3D G3DSA:1.20.1250.20 4 183 2.8E-25 T 06-07-2017 CAL12_RS20880 d86b7b03722b1dc8c7bce490e8c78a49 397 Gene3D G3DSA:1.20.1250.20 200 370 3.2E-9 T 06-07-2017 CAL12_RS20880 d86b7b03722b1dc8c7bce490e8c78a49 397 Pfam PF07690 Major Facilitator Superfamily 8 333 3.0E-33 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23750 7131166bff396d93649fb426a1534d5b 122 Pfam PF00072 Response regulator receiver domain 5 116 5.3E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23750 7131166bff396d93649fb426a1534d5b 122 Gene3D G3DSA:3.40.50.2300 3 119 3.1E-35 T 06-07-2017 CAL12_RS23750 7131166bff396d93649fb426a1534d5b 122 SMART SM00448 3 116 2.7E-35 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS23750 7131166bff396d93649fb426a1534d5b 122 SUPERFAMILY SSF52172 3 120 1.22E-34 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22820 aa61fea6e4b207491a44decfd32ee5d9 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 4 252 8.5E-60 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS22820 aa61fea6e4b207491a44decfd32ee5d9 256 Gene3D G3DSA:3.90.226.10 2 252 9.7E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS22820 aa61fea6e4b207491a44decfd32ee5d9 256 SUPERFAMILY SSF52096 2 252 5.57E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 Gene3D G3DSA:3.10.105.10 293 483 1.4E-37 T 06-07-2017 CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 SUPERFAMILY SSF53850 27 495 5.07E-114 T 06-07-2017 CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 429 2.8E-84 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 Gene3D G3DSA:3.40.190.10 192 292 8.4E-30 T 06-07-2017 CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 PIRSF PIRSF002741 1 497 5.3E-90 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS15050 dfe6c7a3cab3842f95f068587f69f4a4 519 Gene3D G3DSA:3.90.76.10 42 191 1.7E-44 T 06-07-2017 CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 SMART SM00829 15 326 8.5E-33 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 Gene3D G3DSA:3.90.180.10 4 150 6.1E-51 T 06-07-2017 IPR011032 GroES-like CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 SUPERFAMILY SSF51735 115 273 3.11E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 SUPERFAMILY SSF50129 5 148 1.98E-41 T 06-07-2017 IPR011032 GroES-like CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 Pfam PF00107 Zinc-binding dehydrogenase 155 258 5.2E-26 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 32 90 1.2E-9 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 Gene3D G3DSA:3.40.50.720 151 260 4.9E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17820 8b8acc950de17f91420f822a5e30472e 330 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 06-07-2017 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CAL12_RS12895 71135f0bf5e407e477513593b67228ef 211 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 1.3E-24 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 Gene3D G3DSA:3.40.640.10 86 338 9.6E-68 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 Pfam PF00202 Aminotransferase class-III 50 487 2.8E-82 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 273 310 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 SUPERFAMILY SSF53383 440 486 1.5E-109 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 SUPERFAMILY SSF53383 37 406 1.5E-109 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 33 495 2.7E-146 T 06-07-2017 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761 CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 Gene3D G3DSA:3.90.1150.10 437 490 1.2E-44 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS11075 b7671499b6f217dcc1c6572ff707d34f 520 Gene3D G3DSA:3.90.1150.10 339 403 1.2E-44 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 Pfam PF12697 Alpha/beta hydrolase family 14 264 7.2E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 Gene3D G3DSA:3.40.50.1820 1 271 2.5E-65 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 PRINTS PR00412 Epoxide hydrolase signature 95 108 1.3E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 PRINTS PR00412 Epoxide hydrolase signature 18 36 1.3E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 PRINTS PR00412 Epoxide hydrolase signature 81 94 1.3E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 PRINTS PR00412 Epoxide hydrolase signature 246 268 1.3E-10 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS16500 0e0e9b342835e086df0cbd312762c41c 279 SUPERFAMILY SSF53474 1 270 7.63E-68 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 SMART SM00226 3 152 5.9E-50 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 148 6.7E-42 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 SUPERFAMILY SSF52788 1 153 2.09E-53 T 06-07-2017 IPR023485 Phosphotyrosine protein phosphatase I superfamily CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 2.9E-23 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 2.9E-23 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 2.9E-23 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 2.9E-23 T 06-07-2017 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CAL12_RS17185 21d800b7a736dd34a94dbdaf2894584f 163 Gene3D G3DSA:3.40.50.270 1 156 1.3E-55 T 06-07-2017 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 SUPERFAMILY SSF51905 355 412 3.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 SUPERFAMILY SSF51905 2 54 3.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 SUPERFAMILY SSF51905 107 268 3.37E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 SUPERFAMILY SSF54373 270 355 1.07E-10 T 06-07-2017 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 Pfam PF01266 FAD dependent oxidoreductase 4 393 9.5E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 Gene3D G3DSA:3.50.50.60 185 267 4.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 Gene3D G3DSA:3.50.50.60 355 414 4.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 Gene3D G3DSA:3.50.50.60 3 58 4.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS06880 3f719692ecf2fe6bf3c6740093967d57 419 Gene3D G3DSA:3.50.50.60 108 130 4.7E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS16460 21f06e57e9c9bd9c2bc0941865eb07fa 169 Pfam PF13924 Lipocalin-like domain 35 138 5.4E-18 T 06-07-2017 IPR024311 Lipocalin-like domain CAL12_RS11890 5002f45b493474b4121263bc2d4bd94f 135 PIRSF PIRSF002889 1 135 2.6E-39 T 06-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CAL12_RS11890 5002f45b493474b4121263bc2d4bd94f 135 Pfam PF00460 Flagella basal body rod protein 19 39 4.6E-8 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAL12_RS11890 5002f45b493474b4121263bc2d4bd94f 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 133 1.9E-36 T 06-07-2017 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CAL12_RS08485 9b65ee0334792c9ef3a8c239a52371c9 108 PIRSF PIRSF020408 5 107 1.8E-40 T 06-07-2017 IPR016772 Uncharacterised conserved protein UCP020408 CAL12_RS08485 9b65ee0334792c9ef3a8c239a52371c9 108 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 6 97 9.2E-17 T 06-07-2017 IPR016772 Uncharacterised conserved protein UCP020408 CAL12_RS02055 9c4fbcb0026c942b1705a6b34a3860ab 249 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 190 1.0E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS02055 9c4fbcb0026c942b1705a6b34a3860ab 249 SUPERFAMILY SSF53639 5 207 4.71E-58 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS02055 9c4fbcb0026c942b1705a6b34a3860ab 249 Gene3D G3DSA:3.40.225.10 5 218 9.5E-59 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS02055 9c4fbcb0026c942b1705a6b34a3860ab 249 SMART SM01007 10 190 1.4E-62 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS02460 00542fd188f9d9063b7971387075b1ba 379 SUPERFAMILY SSF53850 72 275 1.56E-26 T 06-07-2017 CAL12_RS02460 00542fd188f9d9063b7971387075b1ba 379 Pfam PF09084 NMT1/THI5 like 92 210 6.6E-10 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS02460 00542fd188f9d9063b7971387075b1ba 379 Gene3D G3DSA:3.40.190.10 138 213 1.8E-14 T 06-07-2017 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 Gene3D G3DSA:3.30.70.920 60 143 2.4E-31 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 Gene3D G3DSA:1.10.10.10 7 58 4.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 SUPERFAMILY SSF54909 66 155 2.68E-23 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 SMART SM00344 6 115 6.0E-48 T 06-07-2017 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 5.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 5.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 5.3E-13 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 SUPERFAMILY SSF46785 5 65 5.73E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 1.1E-18 T 06-07-2017 CAL12_RS15795 34b42c158b6f4c940b0e3bd5dfc464f6 157 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 2.3E-25 T 06-07-2017 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 Gene3D G3DSA:1.10.10.10 9 89 4.6E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 Gene3D G3DSA:3.40.190.10 101 192 3.0E-13 T 06-07-2017 CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 SUPERFAMILY SSF46785 9 120 4.42E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 Pfam PF03466 LysR substrate binding domain 97 305 1.9E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 Gene3D G3DSA:3.40.190.10 193 273 2.4E-9 T 06-07-2017 CAL12_RS02860 50eb64d4eee814b3e67240ee8a2345a4 313 SUPERFAMILY SSF53850 100 309 4.1E-27 T 06-07-2017 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.5E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 Gene3D G3DSA:1.10.10.10 7 84 4.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 SUPERFAMILY SSF53850 92 299 2.48E-41 T 06-07-2017 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 Gene3D G3DSA:3.40.190.10 164 266 6.7E-24 T 06-07-2017 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 Pfam PF03466 LysR substrate binding domain 91 299 5.3E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.5E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16745 5205caa14307e6fd5957908e4a805029 302 SUPERFAMILY SSF46785 8 88 3.29E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16610 b90d5037d480d1411081837f8712ea3e 132 Pfam PF03061 Thioesterase superfamily 35 101 1.4E-4 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS16610 b90d5037d480d1411081837f8712ea3e 132 SUPERFAMILY SSF54637 2 124 2.16E-37 T 06-07-2017 IPR029069 HotDog domain CAL12_RS16610 b90d5037d480d1411081837f8712ea3e 132 Gene3D G3DSA:3.10.129.10 2 130 3.9E-39 T 06-07-2017 IPR029069 HotDog domain CAL12_RS16610 b90d5037d480d1411081837f8712ea3e 132 PIRSF PIRSF014972 1 132 7.4E-41 T 06-07-2017 IPR025540 Fluoroacetyl-CoA thioesterase CAL12_RS14225 bc8b202911b12125711e1d854950a0d5 209 Pfam PF13181 Tetratricopeptide repeat 158 185 0.18 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS14225 bc8b202911b12125711e1d854950a0d5 209 Gene3D G3DSA:1.25.40.10 94 183 4.6E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS14225 bc8b202911b12125711e1d854950a0d5 209 SUPERFAMILY SSF48452 65 179 4.3E-12 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS20325 de92f7265432ccc9cf1b47158d17c40a 656 Pfam PF02195 ParB-like nuclease domain 22 117 6.8E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS20325 de92f7265432ccc9cf1b47158d17c40a 656 SUPERFAMILY SSF110849 41 120 7.32E-7 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS20325 de92f7265432ccc9cf1b47158d17c40a 656 Gene3D G3DSA:3.90.1530.10 30 123 4.5E-8 T 06-07-2017 CAL12_RS20325 de92f7265432ccc9cf1b47158d17c40a 656 SUPERFAMILY SSF109709 112 205 2.62E-18 T 06-07-2017 CAL12_RS20325 de92f7265432ccc9cf1b47158d17c40a 656 SMART SM00470 18 118 0.0067 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS27280 9c7f0366bd6be48ffe20e298abe31a2c 318 Gene3D G3DSA:3.40.50.300 77 308 1.0E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27280 9c7f0366bd6be48ffe20e298abe31a2c 318 Pfam PF00005 ABC transporter 95 239 1.1E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27280 9c7f0366bd6be48ffe20e298abe31a2c 318 SUPERFAMILY SSF52540 77 311 7.42E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27280 9c7f0366bd6be48ffe20e298abe31a2c 318 SMART SM00382 103 288 1.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27280 9c7f0366bd6be48ffe20e298abe31a2c 318 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 289 310 1.0E-4 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS14055 1459d0d49558dfc521b2fbecebb0609c 398 Gene3D G3DSA:3.30.1540.10 224 306 9.7E-27 T 06-07-2017 CAL12_RS14055 1459d0d49558dfc521b2fbecebb0609c 398 SUPERFAMILY SSF89796 1 398 1.31E-134 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14055 1459d0d49558dfc521b2fbecebb0609c 398 Pfam PF02515 CoA-transferase family III 4 374 1.3E-119 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS14055 1459d0d49558dfc521b2fbecebb0609c 398 Gene3D G3DSA:3.40.50.10540 2 218 1.2E-112 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14055 1459d0d49558dfc521b2fbecebb0609c 398 Gene3D G3DSA:3.40.50.10540 307 398 1.2E-112 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS25570 f5cf274e9463d06ba60576b25fd5fb79 161 Pfam PF01467 Cytidylyltransferase-like 31 123 1.3E-13 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS25570 f5cf274e9463d06ba60576b25fd5fb79 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 92 5.0E-12 T 06-07-2017 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CAL12_RS25570 f5cf274e9463d06ba60576b25fd5fb79 161 SUPERFAMILY SSF52374 27 157 1.66E-20 T 06-07-2017 CAL12_RS25570 f5cf274e9463d06ba60576b25fd5fb79 161 Gene3D G3DSA:3.40.50.620 28 145 1.4E-30 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 SUPERFAMILY SSF52540 373 554 5.25E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 SUPERFAMILY SSF90123 35 339 2.49E-22 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 Pfam PF00005 ABC transporter 373 514 1.4E-18 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 Gene3D G3DSA:1.20.1560.10 38 336 1.1E-14 T 06-07-2017 CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 Gene3D G3DSA:3.40.50.300 373 556 6.2E-42 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09835 756f03e21a4fca1a6599d7ffdae5a6a4 563 SMART SM00382 375 561 7.4E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Gene3D G3DSA:3.90.1170.50 202 285 1.1E-19 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Gene3D G3DSA:3.30.365.10 72 195 4.6E-37 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 SUPERFAMILY SSF56003 339 750 4.54E-111 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 SMART SM01008 229 309 1.1E-13 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 229 277 4.5E-5 T 06-07-2017 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 PIRSF PIRSF036389 17 755 6.2E-209 T 06-07-2017 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Gene3D G3DSA:3.30.365.10 581 750 6.1E-39 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 71 192 1.4E-26 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 590 703 5.8E-18 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 345 479 4.7E-16 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 522 582 2.7E-6 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 SUPERFAMILY SSF56003 40 262 9.68E-41 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS21720 39dd8417dbb118e03062b5b9458b1c85 762 Gene3D G3DSA:3.30.365.10 400 580 1.6E-38 T 06-07-2017 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 7 379 2.1E-123 T 06-07-2017 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 139 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 Gene3D G3DSA:3.40.630.10 4 184 7.5E-64 T 06-07-2017 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 Gene3D G3DSA:3.40.630.10 325 379 7.5E-64 T 06-07-2017 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 SUPERFAMILY SSF55031 176 282 7.18E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 SUPERFAMILY SSF53187 302 379 7.11E-59 T 06-07-2017 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 SUPERFAMILY SSF53187 4 175 7.11E-59 T 06-07-2017 CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 Pfam PF07687 Peptidase dimerisation domain 172 282 4.8E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 Gene3D G3DSA:3.30.70.360 185 282 8.0E-22 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS08255 418739e3aab2850531e0b96f42285930 383 Pfam PF01546 Peptidase family M20/M25/M40 69 379 2.3E-39 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 Gene3D G3DSA:1.10.10.60 2 67 4.1E-24 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 2.1E-12 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.9E-5 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 SUPERFAMILY SSF48498 81 195 2.86E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16800 9687830ca419476852e7325974c4b364 210 Gene3D G3DSA:1.10.357.10 70 198 4.5E-40 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS16800 9687830ca419476852e7325974c4b364 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS16800 9687830ca419476852e7325974c4b364 210 SUPERFAMILY SSF46689 3 84 3.99E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS00270 9ff2b57110c83b2bb755f562949182d7 220 Gene3D G3DSA:3.40.50.1110 10 210 7.6E-11 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS00270 9ff2b57110c83b2bb755f562949182d7 220 SUPERFAMILY SSF52266 78 210 1.16E-13 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS00270 9ff2b57110c83b2bb755f562949182d7 220 SUPERFAMILY SSF52266 10 50 1.16E-13 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS26600 a80965284451fc82459caed0496771eb 287 PIRSF PIRSF009120 1 248 2.2E-109 T 06-07-2017 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 CAL12_RS26600 a80965284451fc82459caed0496771eb 287 Gene3D G3DSA:3.60.20.10 2 213 3.2E-12 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS26600 a80965284451fc82459caed0496771eb 287 SUPERFAMILY SSF56235 2 241 5.23E-32 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS00820 42f1406b63f6911ac49a1a05667a2c84 247 Pfam PF00977 Histidine biosynthesis protein 3 232 1.1E-77 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAL12_RS00820 42f1406b63f6911ac49a1a05667a2c84 247 Gene3D G3DSA:3.20.20.70 1 238 7.2E-86 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00820 42f1406b63f6911ac49a1a05667a2c84 247 SUPERFAMILY SSF51366 1 238 1.49E-72 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS00820 42f1406b63f6911ac49a1a05667a2c84 247 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 5.2E-76 T 06-07-2017 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAL12_RS00820 42f1406b63f6911ac49a1a05667a2c84 247 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 35.902 T 06-07-2017 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 SUPERFAMILY SSF118352 236 292 1.01E-17 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 Gene3D G3DSA:1.10.287.480 189 234 3.5E-10 T 06-07-2017 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 Gene3D G3DSA:3.90.1280.10 236 292 8.1E-22 T 06-07-2017 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 SUPERFAMILY SSF64397 3 242 7.46E-63 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 Pfam PF01430 Hsp33 protein 3 283 1.5E-81 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 Gene3D G3DSA:3.55.30.10 1 179 1.4E-60 T 06-07-2017 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 294 28.342 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CAL12_RS08665 d80572d8b26520cf72c525218fddf90d 306 PIRSF PIRSF005261 2 295 7.3E-71 T 06-07-2017 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 CAL12_RS00420 9e58bb68f3eaed99304b182070ade3c4 149 SUPERFAMILY SSF54427 27 138 7.43E-25 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS00420 9e58bb68f3eaed99304b182070ade3c4 149 Pfam PF12680 SnoaL-like domain 33 131 1.5E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS00420 9e58bb68f3eaed99304b182070ade3c4 149 Gene3D G3DSA:3.10.450.50 21 133 4.1E-13 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 310 7.9E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 SUPERFAMILY SSF52540 8 257 3.11E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 SMART SM00382 43 235 2.0E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 Gene3D G3DSA:3.40.50.300 6 259 2.0E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 Pfam PF00005 ABC transporter 35 185 1.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS03995 a0c66e2ff0f94bb4ed98d686cfdb36b3 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 330 5.4E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS07835 2ba4bfa2041c5bc8554e635c8fac18bb 291 Pfam PF05681 Fumarate hydratase (Fumerase) 10 280 7.2E-88 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS07835 2ba4bfa2041c5bc8554e635c8fac18bb 291 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 8 282 1.7E-85 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 SUPERFAMILY SSF52738 156 344 1.22E-72 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 Gene3D G3DSA:3.40.50.180 155 344 2.9E-83 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 SMART SM00448 5 124 1.1E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 PIRSF PIRSF000876 2 348 3.2E-137 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 Pfam PF00072 Response regulator receiver domain 7 109 4.1E-25 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 Gene3D G3DSA:3.40.50.2300 3 109 3.5E-28 T 06-07-2017 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 Pfam PF01339 CheB methylesterase 161 340 4.5E-61 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 5 345 41.223 T 06-07-2017 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS11845 b9c485ca8df599ecf0d7f0e4d8cb1157 351 SUPERFAMILY SSF52172 3 109 8.82E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 Gene3D G3DSA:3.50.50.60 3 41 5.1E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 1.2E-134 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 SUPERFAMILY SSF51735 1 182 1.19E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 7.0E-64 T 06-07-2017 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 Gene3D G3DSA:1.10.1040.10 42 325 6.2E-113 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 SUPERFAMILY SSF48179 183 332 6.8E-69 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 1.7E-73 T 06-07-2017 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAL12_RS20935 04ee55afcbe9c177d02ad83e08e40879 338 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 328 44.54 T 06-07-2017 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CAL12_RS27020 b1b48cfc4b2bc12d94b119367882e9b5 317 Pfam PF00535 Glycosyl transferase family 2 17 118 5.4E-18 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS27020 b1b48cfc4b2bc12d94b119367882e9b5 317 SUPERFAMILY SSF53448 15 244 6.28E-39 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS27020 b1b48cfc4b2bc12d94b119367882e9b5 317 Gene3D G3DSA:3.90.550.10 15 229 3.4E-35 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 SUPERFAMILY SSF53901 5 220 3.76E-43 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Gene3D G3DSA:3.40.47.10 131 174 2.7E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Gene3D G3DSA:3.40.47.10 233 366 2.7E-20 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Gene3D G3DSA:3.40.47.10 175 215 1.1E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Gene3D G3DSA:3.40.47.10 17 109 1.1E-25 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 SUPERFAMILY SSF53901 249 366 5.12E-29 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Pfam PF02803 Thiolase, C-terminal domain 256 361 1.2E-9 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 PIRSF PIRSF000429 1 369 5.2E-59 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 ProSitePatterns PS00737 Thiolases signature 2. 315 331 - T 06-07-2017 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CAL12_RS06025 1be377dd3e9e012a8dc215508086c60c 381 Pfam PF00108 Thiolase, N-terminal domain 5 215 9.2E-17 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 16 501 92.519 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 Gene3D G3DSA:3.90.1300.10 9 507 1.2E-169 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 16 501 2.7E-161 T 06-07-2017 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 Pfam PF01425 Amidase 34 490 7.4E-141 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 SUPERFAMILY SSF75304 10 506 6.02E-150 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS25315 769c6b7766e6844e84d684c2ecc0f51d 519 ProSitePatterns PS00571 Amidases signature. 155 186 - T 06-07-2017 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CAL12_RS12890 12d1119d58d099ad6f37e82dbd35803b 257 Gene3D G3DSA:1.10.3720.10 59 249 1.5E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12890 12d1119d58d099ad6f37e82dbd35803b 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 246 4.4E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12890 12d1119d58d099ad6f37e82dbd35803b 257 SUPERFAMILY SSF161098 55 240 6.41E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03395 bbb6768f7f17ceecebae9126de40ee36 231 Gene3D G3DSA:3.40.190.10 3 91 1.4E-10 T 06-07-2017 CAL12_RS03395 bbb6768f7f17ceecebae9126de40ee36 231 Gene3D G3DSA:3.40.190.10 138 151 1.4E-10 T 06-07-2017 CAL12_RS03395 bbb6768f7f17ceecebae9126de40ee36 231 Pfam PF13531 Bacterial extracellular solute-binding protein 5 225 7.6E-30 T 06-07-2017 CAL12_RS03395 bbb6768f7f17ceecebae9126de40ee36 231 SUPERFAMILY SSF53850 3 227 3.09E-33 T 06-07-2017 CAL12_RS07260 652aa7f98f8f15d40c3fa26f77ccf43d 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 300 1.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS18965 1397e22fe92114ff008eec58d929d8ea 240 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 17 235 4.0E-86 T 06-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CAL12_RS18965 1397e22fe92114ff008eec58d929d8ea 240 Gene3D G3DSA:3.40.50.150 28 222 1.3E-47 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS18965 1397e22fe92114ff008eec58d929d8ea 240 Pfam PF13489 Methyltransferase domain 56 210 1.9E-27 T 06-07-2017 CAL12_RS18965 1397e22fe92114ff008eec58d929d8ea 240 SUPERFAMILY SSF53335 19 221 1.45E-46 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS18965 1397e22fe92114ff008eec58d929d8ea 240 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 15 240 36.999 T 06-07-2017 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 SUPERFAMILY SSF55781 102 279 2.09E-27 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 SUPERFAMILY SSF46785 37 109 3.18E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 SMART SM00346 36 126 6.0E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 Pfam PF09339 IclR helix-turn-helix domain 42 88 4.0E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 Gene3D G3DSA:1.10.10.10 35 105 5.5E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 Gene3D G3DSA:3.30.450.40 107 279 1.8E-28 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS11210 68fab512fe1b257136ef17f537b4fda8 284 Pfam PF01614 Bacterial transcriptional regulator 155 275 2.2E-10 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS22925 9328f69377fe5cbaf9e7c0e797b443de 323 Gene3D G3DSA:3.40.50.720 73 121 2.6E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22925 9328f69377fe5cbaf9e7c0e797b443de 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 121 297 7.6E-51 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS22925 9328f69377fe5cbaf9e7c0e797b443de 323 SUPERFAMILY SSF52283 71 131 3.4E-5 T 06-07-2017 CAL12_RS22925 9328f69377fe5cbaf9e7c0e797b443de 323 Gene3D G3DSA:3.40.50.720 122 298 2.4E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22925 9328f69377fe5cbaf9e7c0e797b443de 323 SUPERFAMILY SSF51735 114 298 1.5E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 SUPERFAMILY SSF52402 7 250 1.46E-56 T 06-07-2017 CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 Gene3D G3DSA:3.40.50.620 5 217 3.4E-95 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 Gene3D G3DSA:2.30.30.280 219 292 1.4E-28 T 06-07-2017 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 370 1.1E-124 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 Gene3D G3DSA:2.40.30.10 294 372 6.5E-26 T 06-07-2017 CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 371 37.821 T 06-07-2017 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CAL12_RS17740 e3d70a463a54ec0fa2c901772a1634d1 373 Pfam PF03054 tRNA methyl transferase 10 370 5.9E-128 T 06-07-2017 CAL12_RS11550 d6cb848834c347134b145d9c7e53638c 113 Gene3D G3DSA:3.40.50.410 8 113 1.1E-6 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS11550 d6cb848834c347134b145d9c7e53638c 113 Pfam PF13519 von Willebrand factor type A domain 1 112 1.8E-10 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS11550 d6cb848834c347134b145d9c7e53638c 113 SUPERFAMILY SSF53300 8 113 2.4E-11 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS05730 1821bfb164d1b9239987175dc8920a35 269 SUPERFAMILY SSF53218 7 218 8.51E-34 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05730 1821bfb164d1b9239987175dc8920a35 269 Gene3D G3DSA:3.40.980.10 7 189 3.6E-30 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05730 1821bfb164d1b9239987175dc8920a35 269 Pfam PF00994 Probable molybdopterin binding domain 12 177 1.4E-23 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS05730 1821bfb164d1b9239987175dc8920a35 269 SMART SM00852 11 184 5.4E-31 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 423 1.3E-72 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 3.9E-6 T 06-07-2017 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 3.9E-6 T 06-07-2017 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 3.9E-6 T 06-07-2017 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 SUPERFAMILY SSF103473 7 195 3.14E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 SUPERFAMILY SSF103473 249 469 3.14E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 Pfam PF07690 Major Facilitator Superfamily 17 412 3.7E-45 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 Gene3D G3DSA:1.20.1250.20 266 474 2.3E-17 T 06-07-2017 CAL12_RS27415 3b8b71f1731b60c97588f1a1ab199d9e 482 Gene3D G3DSA:1.20.1250.20 8 190 1.5E-30 T 06-07-2017 CAL12_RS24195 60cc5ec57294a346d4b04884026753ff 294 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 11 273 3.8E-24 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS24195 60cc5ec57294a346d4b04884026753ff 294 Pfam PF03631 Virulence factor BrkB 22 277 1.6E-55 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS24195 60cc5ec57294a346d4b04884026753ff 294 PIRSF PIRSF035875 1 294 4.1E-68 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 127 142 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 113 126 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 189 202 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 102 110 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 203 216 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 271 285 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 PRINTS PR00415 Aconitase family signature 353 366 4.7E-23 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 Pfam PF00330 Aconitase family (aconitate hydratase) 78 411 6.5E-84 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 Gene3D G3DSA:3.30.499.10 3 148 6.3E-25 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 SUPERFAMILY SSF53732 3 420 1.28E-120 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 Gene3D G3DSA:3.30.499.10 275 419 4.3E-46 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 Gene3D G3DSA:3.40.1060.10 149 240 6.4E-28 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS01270 84ed4bc054a2b8fc8673dbf1ba7c9975 421 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 5 417 1.0E-125 T 06-07-2017 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Gene3D G3DSA:3.20.20.140 344 404 1.1E-117 T 06-07-2017 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Gene3D G3DSA:3.20.20.140 70 285 1.1E-117 T 06-07-2017 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Pfam PF07969 Amidohydrolase family 56 464 1.6E-46 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Gene3D G3DSA:3.30.1490.130 288 343 4.0E-29 T 06-07-2017 IPR023100 D-aminoacylase, insert domain GO:0016811 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Gene3D G3DSA:2.30.40.10 405 468 1.2E-12 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 Gene3D G3DSA:2.30.40.10 1 69 7.2E-11 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 SUPERFAMILY SSF51338 1 55 1.73E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 SUPERFAMILY SSF51338 419 478 1.73E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS21505 32139bce19bca87694d14beb0569d16b 493 SUPERFAMILY SSF51556 61 419 3.54E-85 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23120 d31e85f389d6c887dfae94b97329fd1c 437 SUPERFAMILY SSF75304 9 433 3.66E-103 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23120 d31e85f389d6c887dfae94b97329fd1c 437 Gene3D G3DSA:3.90.1300.10 11 433 7.0E-108 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS23120 d31e85f389d6c887dfae94b97329fd1c 437 Pfam PF01425 Amidase 27 421 1.4E-72 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 Gene3D G3DSA:3.40.50.720 395 530 2.7E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 Pfam PF02254 TrkA-N domain 402 514 1.9E-22 T 06-07-2017 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 PRINTS PR00335 TrkA potassium uptake protein signature 418 432 2.7E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 PRINTS PR00335 TrkA potassium uptake protein signature 447 457 2.7E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 PRINTS PR00335 TrkA potassium uptake protein signature 458 468 2.7E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 PRINTS PR00335 TrkA potassium uptake protein signature 401 415 2.7E-7 T 06-07-2017 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 Pfam PF00999 Sodium/hydrogen exchanger family 14 375 7.6E-61 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 285 3.2E-83 T 06-07-2017 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 CAL12_RS15545 0c45797324eaff2291ac94fcf6d65eea 613 SUPERFAMILY SSF51735 401 530 1.09E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02925 0d6ed833af207773cbd521f2da2edd38 127 SUPERFAMILY SSF141673 5 123 8.11E-32 T 06-07-2017 CAL12_RS02925 0d6ed833af207773cbd521f2da2edd38 127 Pfam PF03476 MOSC N-terminal beta barrel domain 6 108 2.6E-12 T 06-07-2017 IPR005303 MOSC, N-terminal beta barrel CAL12_RS20235 a5339ceddb8157cf035a540b8c58c7d7 226 Gene3D G3DSA:2.170.200.10 94 171 1.2E-4 T 06-07-2017 IPR001866 Papillomavirus E2, N-terminal GO:0006275|GO:0006355|GO:0016032 CAL12_RS20235 a5339ceddb8157cf035a540b8c58c7d7 226 PIRSF PIRSF003299 7 226 1.3E-49 T 06-07-2017 IPR026264 Type IV secretion system protein VirB8/PtlE GO:0030255 CAL12_RS20235 a5339ceddb8157cf035a540b8c58c7d7 226 SUPERFAMILY SSF54427 90 225 5.26E-37 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS20235 a5339ceddb8157cf035a540b8c58c7d7 226 Pfam PF04335 VirB8 protein 19 221 3.7E-46 T 06-07-2017 IPR007430 Bacterial virulence protein VirB8 GO:0016020 CAL12_RS25045 ec4cb0dafbb9e505673af8a2f3eefa30 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 31 293 2.1E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS08495 4530ededddbf39242e1563992ef53f04 228 Gene3D G3DSA:3.90.1720.10 99 218 3.6E-42 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAL12_RS08495 4530ededddbf39242e1563992ef53f04 228 Pfam PF00877 NlpC/P60 family 109 215 6.3E-25 T 06-07-2017 IPR000064 Endopeptidase, NLPC/P60 domain CAL12_RS08495 4530ededddbf39242e1563992ef53f04 228 SUPERFAMILY SSF54001 99 216 4.71E-39 T 06-07-2017 CAL12_RS06875 96a478ae46a972a53f54513cec384e3e 237 Pfam PF00005 ABC transporter 21 163 1.7E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS06875 96a478ae46a972a53f54513cec384e3e 237 SUPERFAMILY SSF52540 5 231 5.86E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06875 96a478ae46a972a53f54513cec384e3e 237 Gene3D G3DSA:3.40.50.300 3 227 3.3E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06875 96a478ae46a972a53f54513cec384e3e 237 SMART SM00382 30 228 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS16885 81fc15f12c533bb5384002b952ad391c 129 Gene3D G3DSA:3.30.429.20 1 47 9.5E-4 T 06-07-2017 CAL12_RS16885 81fc15f12c533bb5384002b952ad391c 129 SUPERFAMILY SSF55331 1 112 8.73E-8 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS19020 1f62f63ecd0f6b28a41922d2d05b2eb3 339 Gene3D G3DSA:3.40.190.10 141 244 4.4E-4 T 06-07-2017 CAL12_RS19020 1f62f63ecd0f6b28a41922d2d05b2eb3 339 SUPERFAMILY SSF53850 130 302 5.5E-17 T 06-07-2017 CAL12_RS19020 1f62f63ecd0f6b28a41922d2d05b2eb3 339 PIRSF PIRSF017082 9 338 3.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19020 1f62f63ecd0f6b28a41922d2d05b2eb3 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 335 1.1E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 Gene3D G3DSA:1.10.10.60 240 287 1.8E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 SMART SM00342 202 285 5.2E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 Gene3D G3DSA:1.10.10.60 187 239 7.9E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 Pfam PF06719 AraC-type transcriptional regulator N-terminus 23 173 3.3E-40 T 06-07-2017 IPR009594 Transcription regulator HTH, AraC, N-terminal CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 Pfam PF12833 Helix-turn-helix domain 208 284 6.6E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 SUPERFAMILY SSF46689 187 236 5.82E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS18990 3ab153e3fe8948205349d63e4392c39b 307 SUPERFAMILY SSF46689 239 290 3.94E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS08150 d672df120cf6638ae95ad680393cffaa 390 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 4 384 1.4E-128 T 06-07-2017 IPR016633 Uncharacterised conserved protein UCP015557 CAL12_RS08150 d672df120cf6638ae95ad680393cffaa 390 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 4 385 6.7E-130 T 06-07-2017 IPR016633 Uncharacterised conserved protein UCP015557 CAL12_RS20640 76ad5c86be0eb37a695fb4a45b9dcf81 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 21 315 3.5E-74 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS20640 76ad5c86be0eb37a695fb4a45b9dcf81 331 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 06-07-2017 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CAL12_RS20640 76ad5c86be0eb37a695fb4a45b9dcf81 331 Gene3D G3DSA:3.40.50.1100 75 329 1.5E-60 T 06-07-2017 CAL12_RS20640 76ad5c86be0eb37a695fb4a45b9dcf81 331 SUPERFAMILY SSF53686 10 325 1.7E-88 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS26725 00b59deafc958405a01ce1f7f9272a7f 183 Pfam PF01475 Ferric uptake regulator family 27 145 5.4E-16 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAL12_RS26725 00b59deafc958405a01ce1f7f9272a7f 183 SUPERFAMILY SSF46785 20 150 1.66E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26725 00b59deafc958405a01ce1f7f9272a7f 183 Gene3D G3DSA:1.10.10.10 20 88 3.3E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02295 4d7a84f5c20dd330ca3b69ffab8f3f68 336 Pfam PF13379 NMT1-like family 27 266 1.4E-21 T 06-07-2017 CAL12_RS02295 4d7a84f5c20dd330ca3b69ffab8f3f68 336 Gene3D G3DSA:3.40.190.10 121 252 2.3E-4 T 06-07-2017 CAL12_RS02295 4d7a84f5c20dd330ca3b69ffab8f3f68 336 SUPERFAMILY SSF53850 37 273 3.65E-31 T 06-07-2017 CAL12_RS16075 2e885cb916845e060978657a75f2f627 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 3.9E-96 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16075 2e885cb916845e060978657a75f2f627 329 SUPERFAMILY SSF53850 115 290 2.12E-14 T 06-07-2017 CAL12_RS16075 2e885cb916845e060978657a75f2f627 329 PIRSF PIRSF017082 1 327 1.7E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13965 62341fefea40676bcb6b3c4c017d1b89 301 Gene3D G3DSA:3.60.130.10 2 293 1.7E-78 T 06-07-2017 CAL12_RS13965 62341fefea40676bcb6b3c4c017d1b89 301 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 5 284 5.9E-58 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS13965 62341fefea40676bcb6b3c4c017d1b89 301 SUPERFAMILY SSF51197 5 291 5.95E-74 T 06-07-2017 CAL12_RS27315 002a9d0af543d1e2356452bee353231a 209 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 25 45 - T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27315 002a9d0af543d1e2356452bee353231a 209 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 23 204 1.6E-24 T 06-07-2017 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 CAL12_RS27315 002a9d0af543d1e2356452bee353231a 209 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 21 46 6.4E-8 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27315 002a9d0af543d1e2356452bee353231a 209 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 24 46 1.0E-7 T 06-07-2017 IPR012902 Prokaryotic N-terminal methylation site CAL12_RS27315 002a9d0af543d1e2356452bee353231a 209 SUPERFAMILY SSF54523 27 101 1.88E-10 T 06-07-2017 CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 Gene3D G3DSA:3.40.190.10 114 208 4.6E-15 T 06-07-2017 CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 SMART SM00062 36 255 8.3E-56 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 SUPERFAMILY SSF53850 8 254 1.62E-61 T 06-07-2017 CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 253 2.8E-55 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 Gene3D G3DSA:3.40.190.10 214 254 5.5E-36 T 06-07-2017 CAL12_RS10825 a1b0212f1fbae022c6866055b9b231e9 261 Gene3D G3DSA:3.40.190.10 33 113 5.5E-36 T 06-07-2017 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 Gene3D G3DSA:3.10.420.10 7 155 4.3E-53 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 Pfam PF02556 Preprotein translocase subunit SecB 11 146 1.2E-48 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 77 97 2.5E-26 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 127 145 2.5E-26 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 17 34 2.5E-26 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 101 123 2.5E-26 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 SUPERFAMILY SSF54611 13 153 1.13E-44 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 12 144 7.0E-43 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS26205 5f48ea1eb958bf4cb61fb7d356d506ca 170 Hamap MF_00821 Protein-export protein SecB [secB]. 1 149 29.891 T 06-07-2017 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Pfam PF04607 Region found in RelA / SpoT proteins 289 398 4.5E-31 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Pfam PF13328 HD domain 80 229 3.8E-49 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SUPERFAMILY SSF81301 235 446 1.32E-59 T 06-07-2017 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SUPERFAMILY SSF109604 61 243 2.35E-70 T 06-07-2017 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SUPERFAMILY SSF55021 691 764 1.92E-5 T 06-07-2017 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Gene3D G3DSA:3.30.460.10 246 379 5.7E-42 T 06-07-2017 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Gene3D G3DSA:3.10.20.30 442 502 3.0E-23 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SUPERFAMILY SSF81271 429 502 1.09E-22 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SMART SM00471 95 207 1.5E-8 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Gene3D G3DSA:3.30.70.260 690 760 1.1E-7 T 06-07-2017 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 SMART SM00954 289 399 4.7E-58 T 06-07-2017 IPR007685 RelA/SpoT GO:0015969 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 80 761 1.2E-221 T 06-07-2017 IPR004811 RelA/SpoT family GO:0015969 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Pfam PF13291 ACT domain 690 763 1.7E-15 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS15440 02db540e90467b3de21e9a1bdaabf1be 766 Pfam PF02824 TGS domain 442 501 7.9E-23 T 06-07-2017 IPR004095 TGS KEGG: 00970+6.1.1.3 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 SUPERFAMILY SSF49503 43 197 9.36E-41 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Gene3D G3DSA:2.60.40.420 49 164 2.2E-32 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Pfam PF07732 Multicopper oxidase 55 166 8.2E-39 T 06-07-2017 IPR011707 Multicopper oxidase, type 3 GO:0005507 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 ProSitePatterns PS00079 Multicopper oxidases signature 1. 141 161 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 ProSitePatterns PS00080 Multicopper oxidases signature 2. 610 621 - T 06-07-2017 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 SUPERFAMILY SSF49503 477 627 2.11E-38 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 8 627 3.5E-267 T 06-07-2017 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Gene3D G3DSA:2.60.40.420 511 627 1.3E-36 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 SUPERFAMILY SSF49503 170 378 7.1E-56 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Gene3D G3DSA:2.60.40.420 173 378 1.6E-51 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Pfam PF07731 Multicopper oxidase 510 627 4.2E-27 T 06-07-2017 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 Pfam PF00394 Multicopper oxidase 176 351 1.3E-30 T 06-07-2017 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 CAL12_RS01550 52f611a8ce57de927ebe220e7d76d4c4 628 ProSitePatterns PS00079 Multicopper oxidases signature 1. 605 625 - T 06-07-2017 IPR033138 Multicopper oxidases, conserved site CAL12_RS06340 2c10c9cf6b53787a31130ee70b26256a 245 Gene3D G3DSA:3.40.1130.10 67 228 6.7E-21 T 06-07-2017 CAL12_RS06340 2c10c9cf6b53787a31130ee70b26256a 245 SUPERFAMILY SSF69593 4 240 2.35E-40 T 06-07-2017 CAL12_RS06340 2c10c9cf6b53787a31130ee70b26256a 245 Pfam PF01553 Acyltransferase 62 186 3.3E-20 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS06340 2c10c9cf6b53787a31130ee70b26256a 245 SMART SM00563 74 189 1.0E-32 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS09435 76ffda7cf8820b874d62199a611cd405 427 Gene3D G3DSA:1.20.1250.20 232 418 7.1E-21 T 06-07-2017 CAL12_RS09435 76ffda7cf8820b874d62199a611cd405 427 Gene3D G3DSA:1.20.1250.20 16 200 7.3E-22 T 06-07-2017 CAL12_RS09435 76ffda7cf8820b874d62199a611cd405 427 SUPERFAMILY SSF103473 7 414 1.12E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09435 76ffda7cf8820b874d62199a611cd405 427 Pfam PF07690 Major Facilitator Superfamily 22 356 3.4E-34 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS22625 e941cf038235353aa7b48acba38269e2 225 TIGRFAM TIGR02796 tolQ: protein TolQ 8 222 2.7E-85 T 06-07-2017 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 CAL12_RS22625 e941cf038235353aa7b48acba38269e2 225 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 210 1.4E-42 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 Gene3D G3DSA:3.40.50.880 23 241 7.3E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 SUPERFAMILY SSF52317 22 213 1.11E-41 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 Gene3D G3DSA:1.10.10.60 242 288 5.0E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 318 334 6.0E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 318 6.0E-7 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 SMART SM00342 251 334 4.4E-30 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 Pfam PF12833 Helix-turn-helix domain 257 335 3.3E-26 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 Pfam PF01965 DJ-1/PfpI family 61 195 1.4E-14 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 Gene3D G3DSA:1.10.10.60 289 336 3.9E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 SUPERFAMILY SSF46689 287 336 1.08E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS15125 46d9cb07dfc5c7082ee759b69fc64d3b 340 SUPERFAMILY SSF46689 235 285 7.35E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 SUPERFAMILY SSF47741 95 165 2.36E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 70 8.3E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 Pfam PF01799 [2Fe-2S] binding domain 84 156 2.8E-29 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 Gene3D G3DSA:1.10.150.120 86 166 1.5E-34 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 SUPERFAMILY SSF54292 13 99 3.15E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 Gene3D G3DSA:3.10.20.30 12 85 8.8E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS00165 8c75411385b7ef068bd436d17675210b 181 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS26715 8d801547b27903175e14da6b8270f40a 290 Pfam PF00950 ABC 3 transport family 14 272 1.7E-52 T 06-07-2017 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CAL12_RS26715 8d801547b27903175e14da6b8270f40a 290 SUPERFAMILY SSF81345 12 269 1.7E-23 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS16775 376c02f3ba3ea185c7380ae3125325ed 161 SUPERFAMILY SSF54427 31 154 1.55E-15 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS16775 376c02f3ba3ea185c7380ae3125325ed 161 Gene3D G3DSA:3.10.450.50 31 154 4.9E-8 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS16775 376c02f3ba3ea185c7380ae3125325ed 161 Pfam PF13474 SnoaL-like domain 36 155 7.0E-5 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS21070 74439f0782bddf6a0d0052b76ac12031 178 Pfam PF08808 RES domain 16 157 7.1E-9 T 06-07-2017 IPR014914 RES domain CAL12_RS03985 489898f253ac30ee94928a15b5d098a0 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 2.3E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03985 489898f253ac30ee94928a15b5d098a0 310 Gene3D G3DSA:1.10.3720.10 88 301 8.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03985 489898f253ac30ee94928a15b5d098a0 310 SUPERFAMILY SSF161098 90 287 7.98E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 Hamap MF_00268 Protein RecA [recA]. 13 338 51.628 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 ProSitePatterns PS00321 recA signature. 222 230 - T 06-07-2017 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 SMART SM00382 66 237 4.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 Gene3D G3DSA:3.30.250.10 277 334 6.3E-30 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 Gene3D G3DSA:3.40.50.300 42 276 1.8E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 12 333 3.1E-172 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 Pfam PF00154 recA bacterial DNA recombination protein 15 277 1.9E-145 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 SUPERFAMILY SSF54752 277 335 3.01E-22 T 06-07-2017 IPR023400 DNA recombination and repair protein RecA, C-terminal CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 SUPERFAMILY SSF52540 12 276 8.27E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 306 323 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 102 131 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 219 247 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 252 281 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 136 165 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS09475 70de3c8be14b55727d493ad508cbb9a8 352 PRINTS PR00142 RecA protein signature 174 203 1.7E-83 T 06-07-2017 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CAL12_RS10005 35cc1ad982ea12c7bc0820e86337032e 381 SUPERFAMILY SSF48208 19 375 3.74E-77 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS10005 35cc1ad982ea12c7bc0820e86337032e 381 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 53 370 4.4E-35 T 06-07-2017 CAL12_RS10005 35cc1ad982ea12c7bc0820e86337032e 381 Gene3D G3DSA:1.50.10.10 21 371 1.5E-53 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAL12_RS05850 9aa1057c905d0378c0d8aca67342e0e7 253 Gene3D G3DSA:3.40.50.620 68 201 1.0E-23 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS05850 9aa1057c905d0378c0d8aca67342e0e7 253 Pfam PF02698 DUF218 domain 69 231 8.0E-30 T 06-07-2017 IPR003848 Domain of unknown function DUF218 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 Gene3D G3DSA:3.90.700.10 254 392 1.3E-20 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 Gene3D G3DSA:3.50.50.60 396 457 5.4E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 Gene3D G3DSA:3.50.50.60 2 233 5.4E-48 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 SUPERFAMILY SSF56425 263 400 7.67E-24 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 3 458 1.1E-206 T 06-07-2017 IPR012831 Precorrin 3B synthase CobZ CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 SUPERFAMILY SSF51905 394 460 9.01E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 SUPERFAMILY SSF51905 2 230 9.01E-36 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS12730 507ed32437e6636b56ff67ccbc91ab76 471 Pfam PF00890 FAD binding domain 3 431 3.5E-32 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 SUPERFAMILY SSF54373 428 496 8.63E-6 T 06-07-2017 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 SUPERFAMILY SSF51905 520 581 1.7E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 SUPERFAMILY SSF51905 8 353 1.7E-59 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Pfam PF00732 GMC oxidoreductase 233 346 4.5E-11 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Pfam PF05199 GMC oxidoreductase 446 570 1.9E-21 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Gene3D G3DSA:3.50.50.60 8 158 5.0E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Gene3D G3DSA:3.50.50.60 243 349 5.0E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Gene3D G3DSA:3.50.50.60 511 579 5.0E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS18565 78ad5a997ba3862894c92f9d79462471 590 Gene3D G3DSA:3.50.50.60 454 467 5.0E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15350 ebf14aec3a3fe18628c279476eefa847 316 Pfam PF08340 Domain of unknown function (DUF1732) 215 316 1.7E-32 T 06-07-2017 IPR013551 Domain of unknown function DUF1732 CAL12_RS15350 ebf14aec3a3fe18628c279476eefa847 316 Pfam PF03755 YicC-like family, N-terminal region 2 153 2.9E-36 T 06-07-2017 IPR013527 YicC-like, N-terminal CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 1.6E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 1.6E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 1.6E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 1.6E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 1.6E-13 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 PIRSF PIRSF006648 6 250 1.8E-29 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS08915 aa1c6d8933187339709f17a94f9987ee 253 Pfam PF01061 ABC-2 type transporter 5 216 8.7E-34 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAL12_RS03510 0fe36a059496a1aa2d91bb261e591ded 182 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 129 7.4E-20 T 06-07-2017 CAL12_RS03510 0fe36a059496a1aa2d91bb261e591ded 182 Gene3D G3DSA:3.10.180.10 9 146 2.0E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS03510 0fe36a059496a1aa2d91bb261e591ded 182 SUPERFAMILY SSF54593 10 152 1.19E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS09265 7f96052f4d3393de6f78853dc9606a08 315 TIGRFAM TIGR01932 hflC: HflC protein 141 284 2.5E-44 T 06-07-2017 IPR010200 HflC GO:0016021|GO:0052547 CAL12_RS09265 7f96052f4d3393de6f78853dc9606a08 315 Pfam PF01145 SPFH domain / Band 7 family 24 198 3.1E-27 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS09265 7f96052f4d3393de6f78853dc9606a08 315 PIRSF PIRSF005651 1 290 4.8E-87 T 06-07-2017 IPR010200 HflC GO:0016021|GO:0052547 CAL12_RS09265 7f96052f4d3393de6f78853dc9606a08 315 SMART SM00244 20 185 2.8E-24 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS09265 7f96052f4d3393de6f78853dc9606a08 315 SUPERFAMILY SSF117892 54 191 2.09E-24 T 06-07-2017 IPR001107 Band 7 domain CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 Gene3D G3DSA:3.40.630.10 323 381 3.8E-45 T 06-07-2017 CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 Gene3D G3DSA:3.40.630.10 20 196 3.8E-45 T 06-07-2017 CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 Gene3D G3DSA:3.30.70.360 197 278 4.0E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 81 90 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 Pfam PF01546 Peptidase family M20/M25/M40 83 379 1.5E-26 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 SUPERFAMILY SSF55031 187 280 1.29E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 Pfam PF07687 Peptidase dimerisation domain 184 276 1.2E-17 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 PIRSF PIRSF037238 3 382 3.3E-138 T 06-07-2017 IPR017150 Peptidase M20, glutamate carboxypeptidase CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 SUPERFAMILY SSF53187 18 196 5.28E-47 T 06-07-2017 CAL12_RS25730 d9bd66e0cd079eaf28f54beb87a039a5 382 SUPERFAMILY SSF53187 306 381 5.28E-47 T 06-07-2017 CAL12_RS07080 f8048db7eababf3a4f7409a9260e5a26 343 Pfam PF13416 Bacterial extracellular solute-binding protein 47 300 2.2E-32 T 06-07-2017 CAL12_RS07080 f8048db7eababf3a4f7409a9260e5a26 343 Gene3D G3DSA:3.40.190.10 127 269 3.0E-22 T 06-07-2017 CAL12_RS07080 f8048db7eababf3a4f7409a9260e5a26 343 SUPERFAMILY SSF53850 25 338 4.27E-59 T 06-07-2017 CAL12_RS07080 f8048db7eababf3a4f7409a9260e5a26 343 Gene3D G3DSA:3.40.190.10 270 333 7.7E-23 T 06-07-2017 CAL12_RS07080 f8048db7eababf3a4f7409a9260e5a26 343 Gene3D G3DSA:3.40.190.10 3 123 7.7E-23 T 06-07-2017 CAL12_RS10050 0059d948cd9bbaea6c3154ba5c79d28e 220 Gene3D G3DSA:3.90.550.10 16 219 2.2E-24 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS10050 0059d948cd9bbaea6c3154ba5c79d28e 220 SUPERFAMILY SSF53448 18 219 3.49E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS10050 0059d948cd9bbaea6c3154ba5c79d28e 220 Pfam PF12804 MobA-like NTP transferase domain 20 197 4.4E-27 T 06-07-2017 IPR025877 MobA-like NTP transferase CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 SUPERFAMILY SSF63829 3 312 6.1E-65 T 06-07-2017 CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 41 298 1.5E-61 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 281 299 1.2E-8 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 172 194 1.2E-8 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 236 253 1.2E-8 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 42 59 1.2E-8 T 06-07-2017 IPR005511 Senescence marker protein-30 (SMP-30) CAL12_RS00355 9efecc237ef1f8f6bdcd9b81baf32a76 316 Gene3D G3DSA:2.120.10.30 26 313 8.0E-66 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS13330 bee6b27880df2e3570210118d827a076 257 SUPERFAMILY SSF52540 2 249 1.14E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13330 bee6b27880df2e3570210118d827a076 257 SMART SM00382 26 227 1.9E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13330 bee6b27880df2e3570210118d827a076 257 Pfam PF00005 ABC transporter 17 178 8.8E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13330 bee6b27880df2e3570210118d827a076 257 Gene3D G3DSA:3.40.50.300 2 247 8.9E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13330 bee6b27880df2e3570210118d827a076 257 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 Pfam PF03466 LysR substrate binding domain 83 287 1.8E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 Gene3D G3DSA:3.40.190.10 83 171 3.8E-27 T 06-07-2017 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 56 1.4E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 Gene3D G3DSA:3.40.190.10 172 258 1.7E-25 T 06-07-2017 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 Gene3D G3DSA:1.10.10.10 3 79 3.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 SUPERFAMILY SSF53850 83 288 6.76E-38 T 06-07-2017 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 1.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 1.8E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05750 fed15ccabea8fbf8990421695b416a47 296 SUPERFAMILY SSF46785 2 79 4.84E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 Gene3D G3DSA:3.40.640.10 70 315 9.0E-82 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 Pfam PF00202 Aminotransferase class-III 32 394 8.1E-75 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 SUPERFAMILY SSF53383 2 423 9.46E-131 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 103.755 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 424 2.4E-187 T 06-07-2017 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 Gene3D G3DSA:3.90.1150.10 2 69 1.8E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS24980 397cf12498f6dfcd4466854af5226c8a 427 Gene3D G3DSA:3.90.1150.10 319 423 1.8E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.30.9.10 271 356 2.7E-8 T 06-07-2017 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.30.9.10 135 190 2.7E-8 T 06-07-2017 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.50.50.60 360 412 6.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.50.50.60 191 270 6.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.50.50.60 108 130 6.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Gene3D G3DSA:3.50.50.60 1 58 6.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 SUPERFAMILY SSF54373 271 360 9.94E-7 T 06-07-2017 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 Pfam PF01266 FAD dependent oxidoreductase 2 398 1.1E-54 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 SUPERFAMILY SSF51905 107 271 2.07E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 SUPERFAMILY SSF51905 1 54 2.07E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10225 cb45dfe5bfdde09d84c294d3629eaea0 415 SUPERFAMILY SSF51905 360 412 2.07E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09825 69cb64e569079dfce806c8f9bc984003 350 Pfam PF00144 Beta-lactamase 55 328 2.5E-17 T 06-07-2017 IPR001466 Beta-lactamase-related CAL12_RS09825 69cb64e569079dfce806c8f9bc984003 350 Gene3D G3DSA:3.40.710.10 75 328 4.4E-30 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS09825 69cb64e569079dfce806c8f9bc984003 350 SUPERFAMILY SSF56601 48 336 6.17E-54 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS13625 0f0183278676c107fe3fed2dc8da8807 367 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 91 361 1.7E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13625 0f0183278676c107fe3fed2dc8da8807 367 PIRSF PIRSF017082 39 367 7.0E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13625 0f0183278676c107fe3fed2dc8da8807 367 SUPERFAMILY SSF53850 150 322 3.98E-10 T 06-07-2017 CAL12_RS20375 519d4a66e6e4141ba99767d17038dcd9 139 Gene3D G3DSA:2.30.30.240 55 112 3.4E-10 T 06-07-2017 CAL12_RS20375 519d4a66e6e4141ba99767d17038dcd9 139 Pfam PF05239 PRC-barrel domain 53 122 2.2E-12 T 06-07-2017 IPR027275 PRC-barrel domain CAL12_RS20375 519d4a66e6e4141ba99767d17038dcd9 139 SUPERFAMILY SSF50346 48 135 2.04E-13 T 06-07-2017 IPR011033 PRC-barrel-like CAL12_RS02290 247f710044ae251b4e0297f4ca6922e4 291 Pfam PF00005 ABC transporter 49 190 4.8E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02290 247f710044ae251b4e0297f4ca6922e4 291 SMART SM00382 57 238 4.7E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02290 247f710044ae251b4e0297f4ca6922e4 291 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS02290 247f710044ae251b4e0297f4ca6922e4 291 Gene3D G3DSA:3.40.50.300 26 250 1.4E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02290 247f710044ae251b4e0297f4ca6922e4 291 SUPERFAMILY SSF52540 29 241 3.51E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25475 50ed9403229394d3c0bc746f22c4d387 221 Pfam PF03737 Demethylmenaquinone methyltransferase 21 171 1.3E-35 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS25475 50ed9403229394d3c0bc746f22c4d387 221 Gene3D G3DSA:3.50.30.40 16 177 2.6E-44 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS25475 50ed9403229394d3c0bc746f22c4d387 221 SUPERFAMILY SSF89562 15 180 8.24E-43 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 Pfam PF00884 Sulfatase 7 330 1.8E-71 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 SUPERFAMILY SSF53649 6 419 1.6E-112 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 ProSitePatterns PS00149 Sulfatases signature 2. 112 122 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 ProSitePatterns PS00523 Sulfatases signature 1. 59 71 - T 06-07-2017 IPR024607 Sulfatase, conserved site CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 Gene3D G3DSA:3.40.720.10 4 350 2.4E-100 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS13680 183822f7e0eee92392b147c816b3e2f1 444 Gene3D G3DSA:3.30.1120.10 356 426 1.7E-11 T 06-07-2017 CAL12_RS23440 e77e3337016c7836e9f2b21d2191eb03 348 SUPERFAMILY SSF53850 133 310 1.54E-13 T 06-07-2017 CAL12_RS23440 e77e3337016c7836e9f2b21d2191eb03 348 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 73 344 2.5E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23440 e77e3337016c7836e9f2b21d2191eb03 348 PIRSF PIRSF017082 20 348 7.1E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 SMART SM00382 28 211 2.3E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 Pfam PF08402 TOBE domain 270 356 6.8E-16 T 06-07-2017 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 SUPERFAMILY SSF50331 236 356 8.77E-15 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 SUPERFAMILY SSF52540 4 241 2.8E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 Pfam PF00005 ABC transporter 21 161 3.3E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS01360 3472a8089a3c55057563e2b0785cfabb 358 Gene3D G3DSA:3.40.50.300 3 236 1.9E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18655 264ae4fdcd5ca0232acb3ed7fad17b97 263 SUPERFAMILY SSF52096 2 263 1.41E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS18655 264ae4fdcd5ca0232acb3ed7fad17b97 263 Gene3D G3DSA:1.10.12.10 206 263 6.7E-22 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS18655 264ae4fdcd5ca0232acb3ed7fad17b97 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 262 8.9E-60 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS18655 264ae4fdcd5ca0232acb3ed7fad17b97 263 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 8 263 8.1E-127 T 06-07-2017 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 CAL12_RS18655 264ae4fdcd5ca0232acb3ed7fad17b97 263 Gene3D G3DSA:3.90.226.10 4 203 3.4E-60 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12385 062ebcec4540d2e0a4335161694f63ad 220 SUPERFAMILY SSF53056 6 210 3.66E-60 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS12385 062ebcec4540d2e0a4335161694f63ad 220 Pfam PF00484 Carbonic anhydrase 42 196 2.9E-47 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS12385 062ebcec4540d2e0a4335161694f63ad 220 SMART SM00947 34 201 5.3E-66 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS12385 062ebcec4540d2e0a4335161694f63ad 220 Gene3D G3DSA:3.40.1050.10 6 210 2.4E-63 T 06-07-2017 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS12385 062ebcec4540d2e0a4335161694f63ad 220 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 91 111 - T 06-07-2017 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CAL12_RS00970 ed551610989386de1f9a391758127d5b 427 PIRSF PIRSF006066 1 427 1.8E-141 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS00970 ed551610989386de1f9a391758127d5b 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 421 2.1E-141 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS00970 ed551610989386de1f9a391758127d5b 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 418 1.1E-113 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 285 9.6E-54 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 SUPERFAMILY SSF55021 323 398 1.62E-13 T 06-07-2017 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 SUPERFAMILY SSF52283 3 127 1.91E-38 T 06-07-2017 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 1.7E-34 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 Gene3D G3DSA:3.40.50.720 1 113 2.8E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 06-07-2017 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 Gene3D G3DSA:3.30.70.260 315 397 1.8E-21 T 06-07-2017 CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 SUPERFAMILY SSF51735 99 286 8.42E-60 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25610 ef3af0998292a94ba7ef211f20bc2457 399 Gene3D G3DSA:3.40.50.720 114 288 5.4E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 114 122 1.5E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 301 319 1.5E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 1.5E-7 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 321 3.0E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PIRSF PIRSF037495 5 470 8.0E-143 T 06-07-2017 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 Pfam PF04324 BFD-like [2Fe-2S] binding domain 382 434 2.8E-7 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 Gene3D G3DSA:3.50.50.60 118 191 4.3E-9 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 291 313 1.3E-11 T 06-07-2017 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 113 131 1.3E-11 T 06-07-2017 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.3E-11 T 06-07-2017 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 Gene3D G3DSA:3.50.50.60 267 336 1.6E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 Gene3D G3DSA:3.50.50.60 12 117 1.6E-26 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27140 99c94b117b6e69a11098f2cfb7742f10 478 SUPERFAMILY SSF51905 3 336 8.13E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS08800 35e92cfeaeef14be794a3b6a6bf37b3e 124 SUPERFAMILY SSF55331 2 118 7.77E-27 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS08800 35e92cfeaeef14be794a3b6a6bf37b3e 124 Gene3D G3DSA:3.30.429.20 1 58 4.3E-16 T 06-07-2017 CAL12_RS08800 35e92cfeaeef14be794a3b6a6bf37b3e 124 Gene3D G3DSA:3.30.429.20 64 116 4.2E-14 T 06-07-2017 CAL12_RS08800 35e92cfeaeef14be794a3b6a6bf37b3e 124 Pfam PF01361 Tautomerase enzyme 65 115 3.9E-6 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS08800 35e92cfeaeef14be794a3b6a6bf37b3e 124 Pfam PF01361 Tautomerase enzyme 2 57 5.5E-10 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS08855 1983e72b96b187048fe640b4c5af001b 264 SMART SM00382 31 226 6.4E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08855 1983e72b96b187048fe640b4c5af001b 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08855 1983e72b96b187048fe640b4c5af001b 264 SUPERFAMILY SSF52540 2 235 1.81E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08855 1983e72b96b187048fe640b4c5af001b 264 Gene3D G3DSA:3.40.50.300 1 235 8.5E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08855 1983e72b96b187048fe640b4c5af001b 264 Pfam PF00005 ABC transporter 22 177 4.3E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08730 76017469f110730dc652683591449abb 886 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 06-07-2017 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 SUPERFAMILY SSF50677 236 432 3.56E-49 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Gene3D G3DSA:3.40.50.620 3 233 1.3E-143 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS08730 76017469f110730dc652683591449abb 886 Gene3D G3DSA:3.40.50.620 442 591 1.3E-143 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS08730 76017469f110730dc652683591449abb 886 Gene3D G3DSA:3.40.50.620 638 668 1.3E-143 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS08730 76017469f110730dc652683591449abb 886 Pfam PF09334 tRNA synthetases class I (M) 44 177 9.4E-18 T 06-07-2017 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 885 0.0 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 421 1.0E-63 T 06-07-2017 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CAL12_RS08730 76017469f110730dc652683591449abb 886 SUPERFAMILY SSF47323 682 885 5.23E-30 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Gene3D G3DSA:1.10.730.10 669 822 2.2E-36 T 06-07-2017 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 436 590 8.2E-8 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 640 678 3.6E-5 T 06-07-2017 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Pfam PF08264 Anticodon-binding domain of tRNA 723 847 2.3E-14 T 06-07-2017 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 886 22.393 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 Gene3D G3DSA:3.90.740.10 234 441 4.1E-42 T 06-07-2017 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 576 586 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 PRINTS PR00985 Leucyl-tRNA synthetase signature 543 565 1.2E-47 T 06-07-2017 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CAL12_RS08730 76017469f110730dc652683591449abb 886 SUPERFAMILY SSF52374 434 688 6.97E-146 T 06-07-2017 CAL12_RS08730 76017469f110730dc652683591449abb 886 SUPERFAMILY SSF52374 4 233 6.97E-146 T 06-07-2017 CAL12_RS05125 45f12153b2185b328b87911649b5d8d0 245 PIRSF PIRSF033328 5 236 4.7E-44 T 06-07-2017 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAL12_RS05125 45f12153b2185b328b87911649b5d8d0 245 Pfam PF06299 Protein of unknown function (DUF1045) 60 220 2.5E-51 T 06-07-2017 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Pfam PF02563 Polysaccharide biosynthesis/export protein 49 146 4.4E-24 T 06-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Gene3D G3DSA:3.30.1950.10 57 145 1.2E-24 T 06-07-2017 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Gene3D G3DSA:3.10.560.10 146 225 4.9E-24 T 06-07-2017 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Gene3D G3DSA:3.10.560.10 226 320 1.4E-24 T 06-07-2017 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Pfam PF10531 SLBB domain 237 272 0.0054 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS08015 8c822381ad63262c8823cf170119c4e5 350 Pfam PF10531 SLBB domain 154 205 6.9E-9 T 06-07-2017 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 Gene3D G3DSA:1.10.3860.10 12 417 1.5E-116 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 SUPERFAMILY SSF118215 19 412 8.76E-117 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 12 438 38.191 T 06-07-2017 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 46 61 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 305 328 - T 06-07-2017 IPR018107 Sodium:dicarboxylate symporter, conserved site CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 Pfam PF00375 Sodium:dicarboxylate symporter family 19 411 8.8E-110 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 54 74 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 337 356 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS17900 95fb847788c84bfe2ac9bc20f6b24442 443 PRINTS PR00173 Glutamate-aspartate symporter signature 302 328 1.2E-28 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS22940 47ac3384b73a228d64a2da780fb7839a 206 SUPERFAMILY SSF48317 4 149 9.42E-11 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS22940 47ac3384b73a228d64a2da780fb7839a 206 Gene3D G3DSA:1.20.144.10 73 146 1.2E-5 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS22940 47ac3384b73a228d64a2da780fb7839a 206 Pfam PF01569 PAP2 superfamily 72 143 8.3E-12 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS22940 47ac3384b73a228d64a2da780fb7839a 206 SMART SM00014 6 143 0.0015 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 Gene3D G3DSA:1.10.10.10 17 84 1.1E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 Gene3D G3DSA:3.40.640.10 143 359 4.3E-51 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 SUPERFAMILY SSF46785 9 83 1.14E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 SUPERFAMILY SSF53383 107 466 1.33E-78 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 SMART SM00345 20 79 2.0E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 Pfam PF00155 Aminotransferase class I and II 142 409 3.6E-21 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS16995 8e67a6a1fe78a9bcda50672b65a26690 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 1.5E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS19990 2f99ce3ac730493cc430470d414d49a8 424 Gene3D G3DSA:3.40.50.150 131 408 1.7E-97 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19990 2f99ce3ac730493cc430470d414d49a8 424 SUPERFAMILY SSF53335 26 362 1.64E-77 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19990 2f99ce3ac730493cc430470d414d49a8 424 Pfam PF02353 Mycolic acid cyclopropane synthetase 137 404 5.7E-84 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19990 2f99ce3ac730493cc430470d414d49a8 424 PIRSF PIRSF003085 16 423 4.1E-121 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAL12_RS11855 63d3e10d9c540edcc4b327069a18272a 209 SUPERFAMILY SSF75708 8 208 3.27E-64 T 06-07-2017 CAL12_RS11855 63d3e10d9c540edcc4b327069a18272a 209 Pfam PF04344 Chemotaxis phosphatase, CheZ 13 209 2.7E-78 T 06-07-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CAL12_RS11855 63d3e10d9c540edcc4b327069a18272a 209 Gene3D G3DSA:1.10.287.500 32 164 2.7E-54 T 06-07-2017 CAL12_RS11855 63d3e10d9c540edcc4b327069a18272a 209 PIRSF PIRSF002884 1 209 7.4E-85 T 06-07-2017 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 CAL12_RS11855 63d3e10d9c540edcc4b327069a18272a 209 Gene3D G3DSA:1.20.5.590 7 31 3.1E-12 T 06-07-2017 CAL12_RS13180 5e97bc209cac438d3b5099be68ccf6e6 314 SUPERFAMILY SSF53850 48 248 1.93E-30 T 06-07-2017 CAL12_RS13180 5e97bc209cac438d3b5099be68ccf6e6 314 Pfam PF09084 NMT1/THI5 like 56 184 1.5E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS13180 5e97bc209cac438d3b5099be68ccf6e6 314 Gene3D G3DSA:3.40.190.10 100 204 1.4E-23 T 06-07-2017 CAL12_RS02575 9da38a63cfcc0e50b529426eab76ba95 174 Pfam PF03724 META domain 44 165 4.6E-19 T 06-07-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ CAL12_RS17445 ee05c431210ee360974bb74ce3d2d6ad 354 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 26 327 5.5E-71 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAL12_RS17445 ee05c431210ee360974bb74ce3d2d6ad 354 Gene3D G3DSA:3.40.50.300 51 152 1.1E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17445 ee05c431210ee360974bb74ce3d2d6ad 354 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 340 8.1E-99 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAL12_RS17445 ee05c431210ee360974bb74ce3d2d6ad 354 SUPERFAMILY SSF52540 53 165 6.22E-11 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17445 ee05c431210ee360974bb74ce3d2d6ad 354 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 8 342 37.708 T 06-07-2017 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130 CAL12_RS15745 3db04ca2abb117012a0cd2988af5852f 236 SUPERFAMILY SSF52540 18 234 8.37E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15745 3db04ca2abb117012a0cd2988af5852f 236 Gene3D G3DSA:3.40.50.300 17 234 7.0E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15745 3db04ca2abb117012a0cd2988af5852f 236 Pfam PF00005 ABC transporter 37 182 1.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15745 3db04ca2abb117012a0cd2988af5852f 236 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15745 3db04ca2abb117012a0cd2988af5852f 236 SMART SM00382 46 229 7.0E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01040 b6532fc8c7403d04c4f3797e0ef10c79 77 Pfam PF12512 Protein of unknown function (DUF3717) 4 69 3.4E-26 T 06-07-2017 IPR022191 Protein of unknown function DUF3717 CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Gene3D G3DSA:3.40.50.300 324 539 3.4E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Pfam PF12848 ABC transporter 233 309 1.8E-13 T 06-07-2017 IPR032781 ABC-transporter extension domain CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 556 1.9E-293 T 06-07-2017 IPR022374 ABC transporter, ATP-binding protein, ChvD CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Gene3D G3DSA:3.40.50.300 144 291 2.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Gene3D G3DSA:3.40.50.300 13 109 2.5E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 SUPERFAMILY SSF52540 305 534 6.32E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 SMART SM00382 31 239 4.2E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 SMART SM00382 351 529 9.0E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Pfam PF00005 ABC transporter 343 476 6.5E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 Pfam PF00005 ABC transporter 22 194 2.5E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05490 af151f047e66d5b641a033170f45aa08 557 SUPERFAMILY SSF52540 12 239 1.63E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21980 622418ac3ef3f09bce3aa5a3f4851b71 328 Pfam PF13387 Domain of unknown function (DUF4105) 117 268 7.0E-38 T 06-07-2017 IPR025178 Domain of unknown function DUF4105 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Gene3D G3DSA:1.20.1600.10 136 307 1.0E-82 T 06-07-2017 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Gene3D G3DSA:1.20.1600.10 345 458 1.0E-82 T 06-07-2017 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Gene3D G3DSA:1.20.1600.10 44 83 1.0E-82 T 06-07-2017 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 458 8.1E-125 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Gene3D G3DSA:2.20.200.10 308 343 2.2E-25 T 06-07-2017 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Gene3D G3DSA:2.20.200.10 93 135 2.2E-25 T 06-07-2017 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Pfam PF02321 Outer membrane efflux protein 57 248 4.5E-29 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 Pfam PF02321 Outer membrane efflux protein 280 438 1.9E-18 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS17835 80a5a411520d58d51d1177df2e955c64 478 SUPERFAMILY SSF56954 1 461 1.7E-95 T 06-07-2017 CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 Gene3D G3DSA:3.40.50.720 12 256 1.6E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.9E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 22 251 4.5E-57 T 06-07-2017 CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.5E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 SUPERFAMILY SSF51735 15 254 2.91E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04490 328ab1c171b17421619092d5c7a774e7 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS17980 178487f28e1be9396c7e31a12dfb03f4 282 SUPERFAMILY SSF88713 22 100 2.97E-38 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS17980 178487f28e1be9396c7e31a12dfb03f4 282 SUPERFAMILY SSF88713 136 278 2.97E-38 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS17980 178487f28e1be9396c7e31a12dfb03f4 282 Pfam PF01522 Polysaccharide deacetylase 57 220 4.1E-34 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS17980 178487f28e1be9396c7e31a12dfb03f4 282 Gene3D G3DSA:3.20.20.370 136 226 2.2E-27 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS17980 178487f28e1be9396c7e31a12dfb03f4 282 Gene3D G3DSA:3.20.20.370 36 100 2.2E-27 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS07545 42ecc7bf81ab569d328e80a4e50d4532 71 SUPERFAMILY SSF89807 5 69 2.62E-25 T 06-07-2017 IPR009923 Dodecin CAL12_RS07545 42ecc7bf81ab569d328e80a4e50d4532 71 Pfam PF07311 Dodecin 5 68 2.1E-29 T 06-07-2017 IPR009923 Dodecin CAL12_RS07545 42ecc7bf81ab569d328e80a4e50d4532 71 Gene3D G3DSA:3.30.1660.10 3 69 1.7E-35 T 06-07-2017 IPR025543 Dodecin-like CAL12_RS00175 f7f618ca6ac12003c731f7685fa7882d 296 SUPERFAMILY SSF88713 6 290 4.2E-55 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS00175 f7f618ca6ac12003c731f7685fa7882d 296 Gene3D G3DSA:3.20.20.370 5 288 8.4E-62 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS00175 f7f618ca6ac12003c731f7685fa7882d 296 Pfam PF01522 Polysaccharide deacetylase 64 175 4.3E-10 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS12225 f9641066ec5a6cd851f27e550ffa9cf7 381 Gene3D G3DSA:3.30.70.270 222 380 3.4E-46 T 06-07-2017 CAL12_RS12225 f9641066ec5a6cd851f27e550ffa9cf7 381 SUPERFAMILY SSF55073 226 380 1.96E-42 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS12225 f9641066ec5a6cd851f27e550ffa9cf7 381 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 380 3.5E-41 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS12225 f9641066ec5a6cd851f27e550ffa9cf7 381 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 377 6.5E-37 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS12225 f9641066ec5a6cd851f27e550ffa9cf7 381 SMART SM00267 210 381 3.0E-48 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS21965 23d1c72a1c75d431515110c2550fdcd9 619 SMART SM00382 264 409 0.0094 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS21965 23d1c72a1c75d431515110c2550fdcd9 619 Gene3D G3DSA:3.40.50.300 211 419 1.6E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21965 23d1c72a1c75d431515110c2550fdcd9 619 SUPERFAMILY SSF52540 237 383 5.91E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21965 23d1c72a1c75d431515110c2550fdcd9 619 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 266 608 2.5E-91 T 06-07-2017 IPR018647 Domain of unknown function DUF2075 CAL12_RS04740 42513452424f1a8f9cdd35de8aae4299 170 Gene3D G3DSA:1.20.120.450 1 166 4.7E-70 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAL12_RS04740 42513452424f1a8f9cdd35de8aae4299 170 SUPERFAMILY SSF109854 4 168 5.95E-63 T 06-07-2017 CAL12_RS04740 42513452424f1a8f9cdd35de8aae4299 170 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 2.2E-63 T 06-07-2017 IPR018531 Domain of unknown function DUF1993 CAL12_RS02070 9a4215887abd09f55919727294734679 293 Pfam PF00561 alpha/beta hydrolase fold 22 258 7.8E-19 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS02070 9a4215887abd09f55919727294734679 293 Gene3D G3DSA:3.40.50.1820 2 271 7.9E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02070 9a4215887abd09f55919727294734679 293 SUPERFAMILY SSF53474 1 270 1.31E-58 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS07775 3a10e1a2cb61c544afe355dd324052a7 274 Pfam PF00795 Carbon-nitrogen hydrolase 7 246 2.3E-52 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS07775 3a10e1a2cb61c544afe355dd324052a7 274 Gene3D G3DSA:3.60.110.10 1 266 1.9E-78 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS07775 3a10e1a2cb61c544afe355dd324052a7 274 SUPERFAMILY SSF56317 2 266 1.22E-72 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 Gene3D G3DSA:1.10.10.10 17 99 3.5E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 Gene3D G3DSA:3.40.190.10 119 189 8.4E-6 T 06-07-2017 CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 Gene3D G3DSA:3.40.190.10 190 267 1.4E-10 T 06-07-2017 CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 Pfam PF03466 LysR substrate binding domain 103 298 7.2E-22 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 75 7.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 SUPERFAMILY SSF46785 10 111 1.01E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15300 07a531f8c3636aec41c3f98c8b4ab823 316 SUPERFAMILY SSF53850 105 301 7.78E-25 T 06-07-2017 CAL12_RS07245 cd6b0c27236d6c315e57646af3d472b0 240 SMART SM00382 33 217 5.7E-4 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07245 cd6b0c27236d6c315e57646af3d472b0 240 SUPERFAMILY SSF52540 7 234 7.39E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07245 cd6b0c27236d6c315e57646af3d472b0 240 Pfam PF00005 ABC transporter 24 168 1.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07245 cd6b0c27236d6c315e57646af3d472b0 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07245 cd6b0c27236d6c315e57646af3d472b0 240 Gene3D G3DSA:3.40.50.300 6 232 5.8E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24585 458c82d5d703cab44f1b6b97cdc8717a 388 Gene3D G3DSA:3.30.1540.10 225 296 1.8E-12 T 06-07-2017 CAL12_RS24585 458c82d5d703cab44f1b6b97cdc8717a 388 Gene3D G3DSA:3.40.50.10540 2 211 5.6E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS24585 458c82d5d703cab44f1b6b97cdc8717a 388 Gene3D G3DSA:3.40.50.10540 297 388 5.6E-100 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS24585 458c82d5d703cab44f1b6b97cdc8717a 388 SUPERFAMILY SSF89796 2 388 1.31E-114 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS24585 458c82d5d703cab44f1b6b97cdc8717a 388 Pfam PF02515 CoA-transferase family III 4 364 4.9E-100 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 4.8E-48 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.79 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 SUPERFAMILY SSF50104 2 118 7.02E-44 T 06-07-2017 IPR008991 Translation protein SH3-like domain CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 PRINTS PR00061 Ribosomal protein L19 signature 8 37 1.2E-34 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 PRINTS PR00061 Ribosomal protein L19 signature 92 117 1.2E-34 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 PRINTS PR00061 Ribosomal protein L19 signature 38 67 1.2E-34 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 06-07-2017 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 PIRSF PIRSF002191 1 136 9.5E-52 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS18715 d645ad9a005dfcdd010e017ca86cb7fc 136 Pfam PF01245 Ribosomal protein L19 11 117 1.7E-46 T 06-07-2017 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS13075 1a7d80453133f6fbb9f6c13932525fee 276 Pfam PF00149 Calcineurin-like phosphoesterase 2 232 1.3E-8 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS13075 1a7d80453133f6fbb9f6c13932525fee 276 Gene3D G3DSA:3.60.21.10 1 76 1.7E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS13075 1a7d80453133f6fbb9f6c13932525fee 276 Gene3D G3DSA:3.60.21.10 160 244 1.7E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS13075 1a7d80453133f6fbb9f6c13932525fee 276 SUPERFAMILY SSF56300 1 121 8.39E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS13075 1a7d80453133f6fbb9f6c13932525fee 276 SUPERFAMILY SSF56300 168 256 8.39E-27 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS05085 461028b1881a8054db7f8649fd5adb1d 265 SUPERFAMILY SSF161098 68 257 1.83E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05085 461028b1881a8054db7f8649fd5adb1d 265 Gene3D G3DSA:1.10.3720.10 68 263 4.4E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05085 461028b1881a8054db7f8649fd5adb1d 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 264 1.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05085 461028b1881a8054db7f8649fd5adb1d 265 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 21 264 3.5E-90 T 06-07-2017 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Gene3D G3DSA:1.25.40.10 105 362 1.2E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SUPERFAMILY SSF48452 422 589 5.69E-25 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 200 233 58.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 452 485 17.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 383 416 200.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 558 587 98.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 267 300 470.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 486 520 110.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 521 554 32.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SMART SM00028 301 334 260.0 T 06-07-2017 IPR019734 Tetratricopeptide repeat GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Pfam PF13432 Tetratricopeptide repeat 528 587 9.6E-8 T 06-07-2017 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Pfam PF13432 Tetratricopeptide repeat 456 521 7.5E-6 T 06-07-2017 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Pfam PF13432 Tetratricopeptide repeat 355 409 0.014 T 06-07-2017 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Pfam PF13432 Tetratricopeptide repeat 271 330 1.3E-6 T 06-07-2017 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 Gene3D G3DSA:1.25.40.10 363 578 3.8E-32 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SUPERFAMILY SSF48452 200 337 9.17E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS02780 f0d9c76bd9f885f0d61c76a8a54ec67d 601 SUPERFAMILY SSF48452 366 407 9.17E-14 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS09695 bf0c788289bc627547abbfcd7d861d5a 225 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 213 40.649 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CAL12_RS09695 bf0c788289bc627547abbfcd7d861d5a 225 SUPERFAMILY SSF51366 3 211 5.65E-60 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS09695 bf0c788289bc627547abbfcd7d861d5a 225 Gene3D G3DSA:3.20.20.70 2 212 2.1E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS09695 bf0c788289bc627547abbfcd7d861d5a 225 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 208 1.0E-43 T 06-07-2017 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 Gene3D G3DSA:3.40.390.10 360 502 4.3E-48 T 06-07-2017 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 Gene3D G3DSA:1.10.1370.10 142 349 7.9E-135 T 06-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 Gene3D G3DSA:1.10.1370.10 503 683 7.9E-135 T 06-07-2017 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 Gene3D G3DSA:1.20.1050.40 19 140 1.9E-20 T 06-07-2017 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 Pfam PF01432 Peptidase family M3 224 681 2.7E-132 T 06-07-2017 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 CAL12_RS11720 f1633f662bf73925daa6f0ef5924aabc 687 SUPERFAMILY SSF55486 4 681 1.2E-184 T 06-07-2017 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 Gene3D G3DSA:2.30.40.10 3 95 1.5E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 Gene3D G3DSA:2.30.40.10 289 359 4.2E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 PIRSF PIRSF038971 2 377 2.3E-109 T 06-07-2017 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 SUPERFAMILY SSF51338 2 54 1.58E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 SUPERFAMILY SSF51338 344 385 1.58E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 SUPERFAMILY SSF51556 54 176 2.54E-16 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 SUPERFAMILY SSF51556 213 343 2.54E-16 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS05170 b944ab57aab249e0bf53c727322bb33d 400 Pfam PF01979 Amidohydrolase family 154 376 5.9E-11 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 Pfam PF12833 Helix-turn-helix domain 272 351 1.5E-17 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 Pfam PF01965 DJ-1/PfpI family 42 210 2.2E-14 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 SUPERFAMILY SSF46689 303 352 2.91E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 Gene3D G3DSA:1.10.10.60 306 353 4.4E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 303 345 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 SUPERFAMILY SSF46689 251 299 2.42E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 SUPERFAMILY SSF52317 42 231 4.43E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 SMART SM00342 266 349 4.1E-21 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 Gene3D G3DSA:3.40.50.880 42 231 2.8E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS01830 09862845ee41b7e557d00aae428e005b 356 Gene3D G3DSA:1.10.10.60 251 305 2.6E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS14265 6c2f686d9cc706a10a112b83a11b0294 303 SUPERFAMILY SSF88713 5 284 8.45E-55 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS14265 6c2f686d9cc706a10a112b83a11b0294 303 Gene3D G3DSA:3.20.20.370 4 283 5.0E-59 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS14265 6c2f686d9cc706a10a112b83a11b0294 303 Pfam PF01522 Polysaccharide deacetylase 64 174 3.3E-9 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 SUPERFAMILY SSF53187 7 204 1.15E-49 T 06-07-2017 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 SUPERFAMILY SSF53187 329 416 1.15E-49 T 06-07-2017 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 Gene3D G3DSA:3.30.70.360 214 310 8.1E-27 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 90 99 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 Gene3D G3DSA:3.40.630.10 353 416 4.8E-50 T 06-07-2017 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 Gene3D G3DSA:3.40.630.10 15 213 4.8E-50 T 06-07-2017 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 Pfam PF01546 Peptidase family M20/M25/M40 91 412 1.4E-25 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 Pfam PF07687 Peptidase dimerisation domain 202 306 5.7E-19 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS00510 6a108116931b307a7ce4cbc5ca5992ed 420 SUPERFAMILY SSF55031 205 321 1.12E-23 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS27270 c2a5b5f20af9de2219a28368c09be2ab 410 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 58 74 2.5E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS27270 c2a5b5f20af9de2219a28368c09be2ab 410 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 36 52 2.5E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS27270 c2a5b5f20af9de2219a28368c09be2ab 410 Gene3D G3DSA:3.40.50.2300 35 243 3.4E-44 T 06-07-2017 CAL12_RS27270 c2a5b5f20af9de2219a28368c09be2ab 410 SUPERFAMILY SSF53822 35 394 2.78E-64 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS27270 c2a5b5f20af9de2219a28368c09be2ab 410 Pfam PF13458 Periplasmic binding protein 35 389 8.0E-54 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 SUPERFAMILY SSF46689 267 317 1.43E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 SUPERFAMILY SSF52317 3 194 5.73E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 Gene3D G3DSA:1.10.10.60 268 318 1.3E-13 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 Pfam PF01965 DJ-1/PfpI family 3 175 1.5E-28 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 SMART SM00342 230 313 1.2E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 Gene3D G3DSA:1.10.10.60 221 267 5.6E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 Pfam PF12833 Helix-turn-helix domain 236 315 5.4E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 SUPERFAMILY SSF46689 215 263 5.38E-9 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06435 4a2ca40bd438e8f7d8ba9488a98be7cc 322 Gene3D G3DSA:3.40.50.880 4 220 1.0E-59 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS21770 86f0f7253dea144a42b1a77a5eaad71d 372 Pfam PF02311 AraC-like ligand binding domain 277 353 1.7E-4 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS21770 86f0f7253dea144a42b1a77a5eaad71d 372 SUPERFAMILY SSF51182 37 351 1.13E-46 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS21770 86f0f7253dea144a42b1a77a5eaad71d 372 Gene3D G3DSA:2.60.120.10 45 205 6.5E-27 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS21770 86f0f7253dea144a42b1a77a5eaad71d 372 Gene3D G3DSA:2.60.120.10 215 354 1.1E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS26860 770bad59231db3a53f38201750fcc9ce 282 Pfam PF08241 Methyltransferase domain 77 164 8.7E-15 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAL12_RS26860 770bad59231db3a53f38201750fcc9ce 282 Gene3D G3DSA:3.40.50.150 63 209 4.9E-27 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26860 770bad59231db3a53f38201750fcc9ce 282 SUPERFAMILY SSF53335 58 207 4.1E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 Gene3D G3DSA:1.10.472.20 1 125 1.4E-38 T 06-07-2017 CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 Gene3D G3DSA:2.30.30.50 126 211 9.2E-34 T 06-07-2017 CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 TIGRFAM TIGR03888 nitrile_beta: nitrile hydratase, beta subunit 1 211 1.5E-69 T 06-07-2017 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 Pfam PF02211 Nitrile hydratase beta subunit 1 209 8.6E-62 T 06-07-2017 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 SUPERFAMILY SSF50090 1 211 3.88E-65 T 06-07-2017 IPR008990 Electron transport accessory protein-like domain CAL12_RS21625 4cd56fd9102bed26f61f54a4e6739a20 219 PIRSF PIRSF001427 1 211 2.4E-71 T 06-07-2017 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SUPERFAMILY SSF55785 94 219 4.54E-24 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Gene3D G3DSA:3.30.450.20 219 272 3.3E-5 T 06-07-2017 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SMART SM00388 351 421 1.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SUPERFAMILY SSF55785 218 327 8.97E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SMART SM00091 105 172 2.2E-9 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SMART SM00091 233 304 49.0 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Pfam PF00989 PAS fold 106 218 1.2E-15 T 06-07-2017 IPR013767 PAS fold GO:0006355 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 1.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 1.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 1.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 1.5E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 464 566 1.2E-15 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Gene3D G3DSA:3.30.565.10 421 568 5.5E-33 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SMART SM00086 179 221 4.8E-4 T 06-07-2017 IPR001610 PAC motif CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SUPERFAMILY SSF47384 339 418 2.55E-8 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 418 2.3E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SMART SM00387 463 569 6.8E-28 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 228 4.7E-25 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Gene3D G3DSA:3.30.450.20 93 218 2.1E-23 T 06-07-2017 CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 Pfam PF13188 PAS domain 233 282 0.01 T 06-07-2017 IPR000014 PAS domain CAL12_RS11735 e36530d9e8a0e0d2d45478515257b8a9 584 SUPERFAMILY SSF55874 410 571 1.41E-34 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 68 1.7E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.3E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 SUPERFAMILY SSF53850 94 300 3.44E-33 T 06-07-2017 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 SUPERFAMILY SSF46785 12 114 1.61E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 Gene3D G3DSA:1.10.10.10 11 91 1.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 Gene3D G3DSA:3.40.190.10 181 264 1.6E-18 T 06-07-2017 CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 Pfam PF03466 LysR substrate binding domain 93 298 5.8E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14095 f71885509e29f599897e3180760f1ac8 301 Gene3D G3DSA:3.40.190.10 97 180 6.5E-16 T 06-07-2017 CAL12_RS24290 713686db1e95cd1def60d1474b3e9471 497 Gene3D G3DSA:3.90.1300.10 4 465 1.1E-138 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24290 713686db1e95cd1def60d1474b3e9471 497 Pfam PF01425 Amidase 26 444 4.0E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24290 713686db1e95cd1def60d1474b3e9471 497 SUPERFAMILY SSF75304 4 461 1.02E-131 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 147 8.7E-37 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 SUPERFAMILY SSF51735 8 173 3.16E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 165 325 8.7E-17 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 Gene3D G3DSA:3.30.360.10 164 322 4.5E-56 T 06-07-2017 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 9 348 40.946 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 SUPERFAMILY SSF55347 156 322 4.06E-47 T 06-07-2017 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 Gene3D G3DSA:3.40.50.720 8 163 1.6E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 SMART SM00859 10 148 3.9E-60 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 9 354 1.3E-124 T 06-07-2017 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS24740 6fc88854149a1ed75f4214598e7cb031 354 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 06-07-2017 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS26615 15cbd52c9bb56efcfd6d86824f13a145 112 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 2 104 1.1E-32 T 06-07-2017 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CAL12_RS22725 1cee9a6ca445deb37e67a4ce976670f5 191 PIRSF PIRSF028301 1 174 1.5E-55 T 06-07-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CAL12_RS22725 1cee9a6ca445deb37e67a4ce976670f5 191 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 7 160 6.7E-52 T 06-07-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CAL12_RS22725 1cee9a6ca445deb37e67a4ce976670f5 191 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 11 160 3.8E-54 T 06-07-2017 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 CAL12_RS21510 83cf005e074d56d0d13e6f7e88933244 137 Pfam PF01042 Endoribonuclease L-PSP 28 134 2.2E-27 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS21510 83cf005e074d56d0d13e6f7e88933244 137 Gene3D G3DSA:3.30.1330.40 27 136 1.3E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS21510 83cf005e074d56d0d13e6f7e88933244 137 SUPERFAMILY SSF55298 26 135 5.18E-34 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 285 6.7E-24 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 416 498 4.2E-20 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Gene3D G3DSA:1.10.1040.10 416 494 4.6E-20 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Gene3D G3DSA:1.10.1040.10 190 286 9.2E-25 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 SUPERFAMILY SSF51735 6 187 4.34E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Gene3D G3DSA:3.40.50.720 5 189 2.9E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 SUPERFAMILY SSF48179 416 497 1.7E-18 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 185 7.6E-60 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS01765 57b85ae60e5193fade02043994d1488e 505 SUPERFAMILY SSF48179 187 294 7.14E-27 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS21580 68873c0a46f9f14ebfb5282db58e5d14 598 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 598 35.049 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAL12_RS21580 68873c0a46f9f14ebfb5282db58e5d14 598 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 234 597 1.4E-155 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAL12_RS21580 68873c0a46f9f14ebfb5282db58e5d14 598 PIRSF PIRSF001294 1 598 2.6E-234 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAL12_RS21580 68873c0a46f9f14ebfb5282db58e5d14 598 Pfam PF03814 Potassium-transporting ATPase A subunit 11 596 3.0E-238 T 06-07-2017 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 133 32.866 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 Pfam PF00411 Ribosomal protein S11 23 132 6.4E-50 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 Gene3D G3DSA:3.30.420.80 11 133 7.2E-53 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 SUPERFAMILY SSF53137 18 133 9.16E-47 T 06-07-2017 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 4.0E-55 T 06-07-2017 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 06-07-2017 IPR018102 Ribosomal S11, conserved site CAL12_RS27505 bda5da68af422414659b4571e0f0a8d0 133 PIRSF PIRSF002131 2 133 4.9E-52 T 06-07-2017 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Pfam PF01590 GAF domain 31 157 2.9E-12 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SUPERFAMILY SSF141868 479 720 1.83E-78 T 06-07-2017 IPR001633 EAL domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SMART SM00052 472 717 1.7E-99 T 06-07-2017 IPR001633 EAL domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Pfam PF00563 EAL domain 479 712 3.4E-65 T 06-07-2017 IPR001633 EAL domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SMART SM00065 26 170 6.9E-7 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Gene3D G3DSA:3.20.20.450 479 720 4.8E-87 T 06-07-2017 IPR001633 EAL domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Gene3D G3DSA:3.30.450.40 31 158 3.1E-12 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SUPERFAMILY SSF55073 310 461 1.96E-41 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Gene3D G3DSA:3.30.70.270 307 467 2.2E-47 T 06-07-2017 CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SUPERFAMILY SSF55785 186 303 3.32E-13 T 06-07-2017 IPR000014 PAS domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 302 460 1.3E-33 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Pfam PF00990 Diguanylate cyclase, GGDEF domain 305 457 1.5E-41 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 176 299 7.0E-8 T 06-07-2017 IPR000014 PAS domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 Gene3D G3DSA:3.30.450.20 161 280 2.1E-9 T 06-07-2017 CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SMART SM00267 294 462 4.6E-51 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS19855 f73d5db2a5dc1ea9b408b951951102b3 734 SUPERFAMILY SSF55781 31 166 3.22E-23 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS25990 05dfefb0e9a3681f1b23a7cab046fd8a 226 Gene3D G3DSA:1.10.340.30 32 209 4.7E-71 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS25990 05dfefb0e9a3681f1b23a7cab046fd8a 226 SUPERFAMILY SSF48150 32 209 1.12E-65 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS25990 05dfefb0e9a3681f1b23a7cab046fd8a 226 Pfam PF03352 Methyladenine glycosylase 36 206 8.1E-65 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 SUPERFAMILY SSF56176 1 218 2.29E-54 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 SMART SM01092 225 325 1.6E-29 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Gene3D G3DSA:3.30.390.50 225 325 3.5E-29 T 06-07-2017 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Gene3D G3DSA:3.30.43.10 1 49 1.1E-16 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 SUPERFAMILY SSF55447 224 326 8.5E-26 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 218 6.6E-44 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Gene3D G3DSA:3.30.465.10 157 217 1.2E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Gene3D G3DSA:3.30.465.10 55 111 1.2E-30 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS20670 cfd562f71b2534e17d65d250ca5e4d6d 329 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 325 5.8E-20 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS24880 3472370b6938aa234c2fa6a5251c5fc6 172 Pfam PF08534 Redoxin 45 159 6.8E-19 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAL12_RS24880 3472370b6938aa234c2fa6a5251c5fc6 172 ProSitePatterns PS00194 Thioredoxin family active site. 63 81 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAL12_RS24880 3472370b6938aa234c2fa6a5251c5fc6 172 Gene3D G3DSA:3.40.30.10 7 167 1.0E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS24880 3472370b6938aa234c2fa6a5251c5fc6 172 SUPERFAMILY SSF52833 8 167 2.25E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 Gene3D G3DSA:3.40.190.10 231 314 5.3E-22 T 06-07-2017 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 Gene3D G3DSA:3.40.190.10 148 230 6.4E-27 T 06-07-2017 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 SUPERFAMILY SSF53850 144 348 9.77E-33 T 06-07-2017 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 60 119 1.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 86 96 8.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 96 107 8.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 75 86 8.9E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 SUPERFAMILY SSF46785 54 140 6.53E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 Gene3D G3DSA:1.10.10.10 52 140 3.2E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25415 384a67a0f72fa90116984b7dac081082 354 Pfam PF03466 LysR substrate binding domain 144 345 7.7E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS22460 b814c1a3704922b68aaf5014724d3745 561 SUPERFAMILY SSF53649 310 518 1.18E-17 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS22460 b814c1a3704922b68aaf5014724d3745 561 Gene3D G3DSA:3.40.720.10 370 520 9.2E-9 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS22460 b814c1a3704922b68aaf5014724d3745 561 Pfam PF04185 Phosphoesterase family 44 529 8.9E-97 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS22460 b814c1a3704922b68aaf5014724d3745 561 TIGRFAM TIGR03397 acid_phos_Burk: acid phosphatase, Burkholderia-type 44 557 2.8E-190 T 06-07-2017 IPR017768 Acid phosphatase, AcpA CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 SUPERFAMILY SSF51182 13 440 1.96E-164 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 Gene3D G3DSA:2.60.120.10 203 228 2.5E-64 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 Gene3D G3DSA:2.60.120.10 289 407 2.5E-64 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 14 439 68.468 T 06-07-2017 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 Pfam PF04209 homogentisate 1,2-dioxygenase 14 437 8.4E-195 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAL12_RS02765 23b2a274675b97a934ceff2c6ce7b8c9 442 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 13 437 3.6E-192 T 06-07-2017 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CAL12_RS11830 6a2503769b479d27cb215e2028389b24 166 SMART SM00260 14 153 2.1E-39 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11830 6a2503769b479d27cb215e2028389b24 166 Gene3D G3DSA:2.30.30.40 95 146 3.0E-7 T 06-07-2017 CAL12_RS11830 6a2503769b479d27cb215e2028389b24 166 SUPERFAMILY SSF50341 18 158 3.79E-38 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11830 6a2503769b479d27cb215e2028389b24 166 Gene3D G3DSA:2.40.50.180 58 94 2.2E-10 T 06-07-2017 CAL12_RS11830 6a2503769b479d27cb215e2028389b24 166 Pfam PF01584 CheW-like domain 18 155 1.6E-35 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 205 325 4.3E-22 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 Gene3D G3DSA:3.40.50.720 7 202 2.6E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 Gene3D G3DSA:1.10.1040.10 205 328 8.8E-30 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 11 199 5.4E-22 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 SUPERFAMILY SSF51735 9 101 1.78E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 SUPERFAMILY SSF51735 132 202 1.78E-22 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04470 4b50304ff28413f9c103e2d43ad2460b 331 SUPERFAMILY SSF48179 204 327 1.47E-26 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS07960 e1307513c2e8d0e0aa3073b9c76372db 186 Gene3D G3DSA:2.160.10.10 20 181 7.6E-37 T 06-07-2017 CAL12_RS07960 e1307513c2e8d0e0aa3073b9c76372db 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 160 1.3E-5 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS07960 e1307513c2e8d0e0aa3073b9c76372db 186 SUPERFAMILY SSF51161 23 183 1.12E-36 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 2.1E-18 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 SUPERFAMILY SSF52833 1 101 3.16E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 Gene3D G3DSA:3.40.30.10 1 89 1.2E-26 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 SUPERFAMILY SSF47616 69 201 1.53E-23 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 Gene3D G3DSA:1.20.1050.10 90 200 7.4E-20 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS17730 e7ba8970633ea84ba28779c59492657f 204 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 186 7.4E-8 T 06-07-2017 CAL12_RS15405 845ac9bf375259b8397813631c7d289c 316 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 12 294 7.9E-57 T 06-07-2017 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 CAL12_RS02550 05a93bd8a44c6db5f4861c5f8884e0e3 98 Gene3D G3DSA:3.30.70.900 1 93 3.5E-11 T 06-07-2017 CAL12_RS02550 05a93bd8a44c6db5f4861c5f8884e0e3 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 4.8E-9 T 06-07-2017 IPR007138 Antibiotic biosynthesis monooxygenase domain CAL12_RS02550 05a93bd8a44c6db5f4861c5f8884e0e3 98 SUPERFAMILY SSF54909 1 95 2.02E-28 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS26895 7f0c4c817d8a6f5ee7ec42e094e6bd5f 364 Pfam PF01757 Acyltransferase family 1 338 8.0E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAL12_RS05370 cebc3d0b64790021cdf0d23352f53c59 230 Gene3D G3DSA:1.10.3720.10 18 226 3.7E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05370 cebc3d0b64790021cdf0d23352f53c59 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 121 2.3E-23 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS05370 cebc3d0b64790021cdf0d23352f53c59 230 SUPERFAMILY SSF161098 18 220 6.54E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05370 cebc3d0b64790021cdf0d23352f53c59 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 226 3.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 Pfam PF03466 LysR substrate binding domain 89 289 1.6E-27 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 SUPERFAMILY SSF53850 90 292 9.19E-28 T 06-07-2017 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 Gene3D G3DSA:1.10.10.10 1 86 5.4E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 Gene3D G3DSA:3.40.190.10 178 259 1.2E-14 T 06-07-2017 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 Gene3D G3DSA:3.40.190.10 90 177 2.5E-12 T 06-07-2017 CAL12_RS04155 7921db619198f4f38715c9d58e6b14ae 318 SUPERFAMILY SSF46785 1 80 1.41E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10845 0700d7f0cacea18d5e8964879c7dd7ed 316 SUPERFAMILY SSF53474 21 308 2.04E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10845 0700d7f0cacea18d5e8964879c7dd7ed 316 Gene3D G3DSA:3.40.50.1820 23 299 3.0E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10845 0700d7f0cacea18d5e8964879c7dd7ed 316 Pfam PF12146 Serine aminopeptidase, S33 77 293 9.8E-17 T 06-07-2017 IPR022742 Serine aminopeptidase, S33 CAL12_RS20320 80004c276d76587e2d56ade6ddd4d9f1 103 PIRSF PIRSF039032 1 103 1.1E-39 T 06-07-2017 IPR009387 Toxin HigB-2 CAL12_RS20320 80004c276d76587e2d56ade6ddd4d9f1 103 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 41 102 4.0E-10 T 06-07-2017 IPR009387 Toxin HigB-2 CAL12_RS04625 852024091a8d67bd3c8c1aa2875cafa3 101 SUPERFAMILY SSF47413 21 79 8.45E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS04625 852024091a8d67bd3c8c1aa2875cafa3 101 Gene3D G3DSA:1.10.260.40 20 73 2.4E-9 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS04625 852024091a8d67bd3c8c1aa2875cafa3 101 Pfam PF13560 Helix-turn-helix domain 22 75 2.5E-10 T 06-07-2017 CAL12_RS10620 a79fe04dfe76624680e08768ad9d0951 234 Pfam PF01738 Dienelactone hydrolase family 22 232 4.9E-39 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAL12_RS10620 a79fe04dfe76624680e08768ad9d0951 234 Gene3D G3DSA:3.40.50.1820 5 233 2.8E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10620 a79fe04dfe76624680e08768ad9d0951 234 SUPERFAMILY SSF53474 4 233 3.44E-42 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23530 dfb0e04948f328ebedb03620233f65cf 366 Pfam PF04909 Amidohydrolase 118 364 2.1E-24 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23530 dfb0e04948f328ebedb03620233f65cf 366 Gene3D G3DSA:3.20.20.140 5 365 4.5E-61 T 06-07-2017 CAL12_RS23530 dfb0e04948f328ebedb03620233f65cf 366 SUPERFAMILY SSF51556 5 33 4.33E-62 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23530 dfb0e04948f328ebedb03620233f65cf 366 SUPERFAMILY SSF51556 70 365 4.33E-62 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS10960 a4565c2dcd2f1fec78c4113707d79b5d 139 Pfam PF00472 RF-1 domain 6 132 8.1E-25 T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAL12_RS10960 a4565c2dcd2f1fec78c4113707d79b5d 139 SUPERFAMILY SSF75620 8 106 2.28E-12 T 06-07-2017 CAL12_RS10960 a4565c2dcd2f1fec78c4113707d79b5d 139 Gene3D G3DSA:3.30.160.200 2 101 4.3E-32 T 06-07-2017 CAL12_RS10960 a4565c2dcd2f1fec78c4113707d79b5d 139 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 06-07-2017 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 3.3E-35 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 SUPERFAMILY SSF82607 10 102 1.57E-34 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 PIRSF PIRSF004555 2 108 1.8E-37 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 7.9E-32 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 Gene3D G3DSA:3.30.1310.10 1 108 1.5E-48 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS06470 7459992094d3001bf9d7eb5f93d18571 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 22.181 T 06-07-2017 IPR004401 Nucleoid-associated protein YbaB/EbfC family CAL12_RS03445 1e41da59698bf84f35f1bdd7ded28c43 326 PIRSF PIRSF017082 2 325 3.4E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03445 1e41da59698bf84f35f1bdd7ded28c43 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 6.1E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03445 1e41da59698bf84f35f1bdd7ded28c43 326 SUPERFAMILY SSF53850 107 284 1.86E-10 T 06-07-2017 CAL12_RS16370 7585ac5f3f69061bf0ead9f943d8fef6 199 Gene3D G3DSA:1.10.340.30 7 184 6.8E-77 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS16370 7585ac5f3f69061bf0ead9f943d8fef6 199 Pfam PF03352 Methyladenine glycosylase 11 183 6.3E-76 T 06-07-2017 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CAL12_RS16370 7585ac5f3f69061bf0ead9f943d8fef6 199 SUPERFAMILY SSF48150 7 187 1.28E-74 T 06-07-2017 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 SMART SM00347 43 143 1.1E-18 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 SUPERFAMILY SSF46785 18 157 6.83E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 99 9.2E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 103 119 9.2E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 133 153 9.2E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 Pfam PF01047 MarR family 50 107 2.5E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS17830 c626b7d107fec42211527595d0a5559b 166 Gene3D G3DSA:1.10.10.10 12 156 5.5E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 Pfam PF00850 Histone deacetylase domain 20 303 4.5E-82 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 5.6E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 5.6E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 PRINTS PR01270 Histone deacetylase superfamily signature 234 244 5.6E-17 T 06-07-2017 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 SUPERFAMILY SSF52768 1 305 3.6E-104 T 06-07-2017 CAL12_RS18875 0e14bdcbb75153c2a18284c453a34b52 307 Gene3D G3DSA:3.40.800.20 3 305 7.0E-104 T 06-07-2017 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CAL12_RS06605 5918c6fba16dfacc3777c2ec1bd8600d 281 SUPERFAMILY SSF53639 45 249 8.83E-37 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS06605 5918c6fba16dfacc3777c2ec1bd8600d 281 Gene3D G3DSA:3.40.225.10 46 250 6.5E-44 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS06605 5918c6fba16dfacc3777c2ec1bd8600d 281 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 51 224 1.4E-31 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS06605 5918c6fba16dfacc3777c2ec1bd8600d 281 SMART SM01007 50 234 2.3E-18 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 SMART SM00855 3 189 1.0E-29 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 Gene3D G3DSA:3.40.50.1240 1 248 9.4E-100 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 2 246 1.3E-117 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.119 T 06-07-2017 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 SUPERFAMILY SSF53254 1 245 5.89E-79 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 120 2.0E-29 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS26190 8f4e91740f205ab9075501899b17ac2b 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 219 2.4E-6 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 SMART SM00345 25 83 1.4E-15 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 SUPERFAMILY SSF46785 18 87 2.64E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 54 73 1.5E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 54 1.5E-6 T 06-07-2017 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 Gene3D G3DSA:1.10.10.10 10 84 1.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 SUPERFAMILY SSF48008 90 225 2.33E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 SMART SM00895 93 217 5.5E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 6.7E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 9.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 9.2E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 Gene3D G3DSA:1.20.120.530 87 228 1.3E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS03145 25961e48d7971a08dad7853db1b2dd9b 234 Pfam PF07729 FCD domain 93 216 1.9E-25 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS07440 ce02c50b6e1a506d5b6c61daff8f74ab 476 Gene3D G3DSA:3.40.309.10 260 445 1.4E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS07440 ce02c50b6e1a506d5b6c61daff8f74ab 476 Pfam PF00171 Aldehyde dehydrogenase family 15 470 1.9E-147 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS07440 ce02c50b6e1a506d5b6c61daff8f74ab 476 SUPERFAMILY SSF53720 3 471 6.81E-148 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS07440 ce02c50b6e1a506d5b6c61daff8f74ab 476 Gene3D G3DSA:3.40.605.10 2 259 6.9E-86 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS07440 ce02c50b6e1a506d5b6c61daff8f74ab 476 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS00325 59c29fb04fa9a49389200ef9e3136c20 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 306 4.0E-39 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 SMART SM00347 29 130 7.3E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 Gene3D G3DSA:1.10.10.10 13 141 6.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 SUPERFAMILY SSF46785 12 145 4.26E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 Pfam PF12802 MarR family 46 94 1.6E-10 T 06-07-2017 CAL12_RS16180 05d7a9e512283bd94677699c5cf8604d 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 69 103 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS23045 4657949451de51042b374c56c86d6649 297 Gene3D G3DSA:3.40.190.10 93 179 2.0E-8 T 06-07-2017 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 SUPERFAMILY SSF53850 92 296 8.07E-30 T 06-07-2017 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 Gene3D G3DSA:3.40.190.10 180 264 9.6E-14 T 06-07-2017 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 Pfam PF03466 LysR substrate binding domain 90 295 5.3E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23045 4657949451de51042b374c56c86d6649 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.5E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23045 4657949451de51042b374c56c86d6649 297 Gene3D G3DSA:1.10.10.10 4 88 3.6E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23045 4657949451de51042b374c56c86d6649 297 SUPERFAMILY SSF46785 4 89 4.97E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23045 4657949451de51042b374c56c86d6649 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09685 3ca96517755932f6fd44b8657fdd8179 712 Gene3D G3DSA:3.10.350.10 170 222 2.1E-4 T 06-07-2017 IPR018392 LysM domain CAL12_RS09685 3ca96517755932f6fd44b8657fdd8179 712 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 174 244 6.3E-21 T 06-07-2017 IPR020012 Motility protein FimV, N-terminal CAL12_RS24405 ae546397e57afcec2ab403bf15a8b36d 145 Gene3D G3DSA:2.60.120.10 14 136 6.0E-32 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS24405 ae546397e57afcec2ab403bf15a8b36d 145 Pfam PF07883 Cupin domain 58 108 1.3E-6 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS24405 ae546397e57afcec2ab403bf15a8b36d 145 SUPERFAMILY SSF51182 14 128 7.0E-16 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 SUPERFAMILY SSF51126 1 100 3.04E-9 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 Gene3D G3DSA:2.160.20.20 1 100 3.1E-7 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 Pfam PF12951 Passenger-associated-transport-repeat 7 35 2.6E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 Pfam PF12951 Passenger-associated-transport-repeat 73 100 7.1E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 72 101 6.3E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23655 8cf6610acbc35d19909161204a798c70 101 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 6 35 2.1E-12 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 SUPERFAMILY SSF51126 1 121 4.08E-14 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 93 123 2.5E-10 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 6 37 8.5E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 Gene3D G3DSA:2.160.20.20 1 122 4.9E-14 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 Pfam PF12951 Passenger-associated-transport-repeat 7 35 1.1E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23695 6c65ebc6f79be9d9e6aa0311e8d460e9 123 Pfam PF12951 Passenger-associated-transport-repeat 95 122 1.4E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS01100 7a6fe5bcba4200ed7b8adce90f7deaa8 158 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 117 6.2E-19 T 06-07-2017 IPR002850 PIN family, putative toxin-antitoxin system toxin component CAL12_RS01100 7a6fe5bcba4200ed7b8adce90f7deaa8 158 Pfam PF13470 PIN domain 3 112 6.7E-25 T 06-07-2017 IPR002716 PIN domain CAL12_RS01100 7a6fe5bcba4200ed7b8adce90f7deaa8 158 SUPERFAMILY SSF88723 1 120 6.17E-13 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 Gene3D G3DSA:3.40.50.720 1 244 2.2E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 240 4.1E-56 T 06-07-2017 CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.6E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 SUPERFAMILY SSF51735 5 244 2.6E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 201 0.0049 T 06-07-2017 CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27295 58fe50fda592efcd5c1b254466f20432 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.3E-38 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18740 4717548f3581dec51a57afaac229ae53 262 Gene3D G3DSA:3.40.50.620 19 205 2.1E-49 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS18740 4717548f3581dec51a57afaac229ae53 262 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 209 5.2E-37 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAL12_RS18740 4717548f3581dec51a57afaac229ae53 262 SUPERFAMILY SSF52402 13 197 1.16E-42 T 06-07-2017 CAL12_RS18740 4717548f3581dec51a57afaac229ae53 262 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 40 233 1.1E-77 T 06-07-2017 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 CAL12_RS18740 4717548f3581dec51a57afaac229ae53 262 PIRSF PIRSF000857 13 239 2.8E-76 T 06-07-2017 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 Gene3D G3DSA:1.10.10.10 161 221 5.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 74 219 1.9E-24 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 Gene3D G3DSA:1.10.1740.10 54 160 1.4E-22 T 06-07-2017 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 SUPERFAMILY SSF88946 49 153 3.14E-23 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 Pfam PF08281 Sigma-70, region 4 164 216 1.4E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 SUPERFAMILY SSF88659 134 220 5.89E-13 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS19970 e3c6c651a39731793df299f76a9f9829 222 Pfam PF04542 Sigma-70 region 2 71 137 1.4E-16 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 28.729 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 Pfam PF07549 SecD/SecF GG Motif 32 59 1.7E-8 T 06-07-2017 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 Pfam PF02355 Protein export membrane protein 108 291 1.0E-63 T 06-07-2017 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 Gene3D G3DSA:1.20.1640.10 102 300 4.2E-29 T 06-07-2017 CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 7.0E-75 T 06-07-2017 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 116 280 2.0E-48 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 4.5E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 4.5E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 4.5E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 4.5E-27 T 06-07-2017 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CAL12_RS04915 6743dc37bf625fab54f79554833ce247 309 SUPERFAMILY SSF82866 72 294 1.26E-39 T 06-07-2017 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.402 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Gene3D G3DSA:3.40.50.300 201 266 2.2E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Gene3D G3DSA:3.40.50.300 4 130 2.2E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 SUPERFAMILY SSF81271 279 359 3.05E-36 T 06-07-2017 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 5.0E-22 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Gene3D G3DSA:1.10.150.300 131 200 5.3E-27 T 06-07-2017 IPR023192 TGS-like domain CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 4.4E-156 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 PIRSF PIRSF006641 1 363 1.6E-152 T 06-07-2017 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Gene3D G3DSA:3.10.20.30 267 363 3.7E-50 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 SUPERFAMILY SSF52540 3 301 1.15E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.6E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.6E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.6E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.6E-34 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS02830 31d445a966abd02942f7b8679bdc3c7a 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 8.0E-40 T 06-07-2017 IPR013029 Domain of unknown function DUF933 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 29 433 5.3E-156 T 06-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 SUPERFAMILY SSF69304 163 434 2.75E-57 T 06-07-2017 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Hamap MF_00671 Protein TolB [tolB]. 19 432 34.319 T 06-07-2017 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 SUPERFAMILY SSF52964 45 170 5.89E-32 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Gene3D G3DSA:2.130.10.10 162 434 2.5E-80 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Pfam PF04052 TolB amino-terminal domain 38 137 6.4E-24 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Pfam PF07676 WD40-like Beta Propeller Repeat 331 364 1.0E-8 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Pfam PF07676 WD40-like Beta Propeller Repeat 244 278 2.3E-8 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Pfam PF07676 WD40-like Beta Propeller Repeat 206 234 3.8E-8 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Pfam PF07676 WD40-like Beta Propeller Repeat 286 322 2.5E-13 T 06-07-2017 IPR011659 WD40-like Beta Propeller CAL12_RS22640 d15752498689ad393ec23cc6465ead2c 437 Gene3D G3DSA:3.40.50.10070 37 161 1.2E-39 T 06-07-2017 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 CAL12_RS22320 2db9078c89f4397aacdf7e1652861fec 191 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 43 179 5.0E-56 T 06-07-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CAL12_RS22320 2db9078c89f4397aacdf7e1652861fec 191 SUPERFAMILY SSF56925 33 191 2.04E-68 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS22320 2db9078c89f4397aacdf7e1652861fec 191 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 44 187 1.8E-62 T 06-07-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CAL12_RS22320 2db9078c89f4397aacdf7e1652861fec 191 Gene3D G3DSA:2.40.160.20 34 191 2.8E-67 T 06-07-2017 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CAL12_RS22320 2db9078c89f4397aacdf7e1652861fec 191 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 10 191 36.66 T 06-07-2017 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP KEGG: 00565+2.3.1.25 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 4 301 1.8E-134 T 06-07-2017 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 5 303 50.702 T 06-07-2017 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 PIRSF PIRSF001365 7 304 8.5E-57 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 Pfam PF00701 Dihydrodipicolinate synthetase family 13 299 1.0E-50 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 SUPERFAMILY SSF51569 12 302 3.56E-66 T 06-07-2017 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 Gene3D G3DSA:3.20.20.70 13 302 2.2E-74 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS18600 fd2e18d554caa13a9fae4d4ec6e15b12 304 SMART SM01130 11 302 2.5E-72 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 432 1.9E-71 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 Gene3D G3DSA:3.90.76.10 61 149 4.2E-21 T 06-07-2017 CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 SUPERFAMILY SSF53850 26 521 8.87E-102 T 06-07-2017 CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 PIRSF PIRSF002741 4 515 1.8E-67 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 Gene3D G3DSA:3.10.105.10 295 497 3.1E-28 T 06-07-2017 CAL12_RS24080 a3a4e5857185f75e13c3df467623b825 525 Gene3D G3DSA:3.40.190.10 150 294 4.2E-35 T 06-07-2017 CAL12_RS27290 e01f22c5ee60fd72cdcec77956fb357d 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 298 2.1E-30 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS05000 e0d62ca3185e4d6932c9d82f2b98cc52 154 Pfam PF01337 Barstar (barnase inhibitor) 43 123 2.1E-13 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAL12_RS05000 e0d62ca3185e4d6932c9d82f2b98cc52 154 Gene3D G3DSA:3.30.370.10 41 128 4.3E-14 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAL12_RS05000 e0d62ca3185e4d6932c9d82f2b98cc52 154 SUPERFAMILY SSF52038 41 128 2.22E-11 T 06-07-2017 IPR000468 Barstar (barnase inhibitor) CAL12_RS12545 f48e291f05a4816706ceef503e9354cf 317 SUPERFAMILY SSF53850 102 271 1.41E-14 T 06-07-2017 CAL12_RS12545 f48e291f05a4816706ceef503e9354cf 317 PIRSF PIRSF017082 1 316 1.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12545 f48e291f05a4816706ceef503e9354cf 317 Gene3D G3DSA:3.40.190.10 120 238 3.4E-4 T 06-07-2017 CAL12_RS12545 f48e291f05a4816706ceef503e9354cf 317 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 313 2.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26785 d50f26442aa5d4e4f4b50ffc0f600282 91 Gene3D G3DSA:3.30.70.1460 7 91 7.7E-30 T 06-07-2017 IPR027471 YbeD-like domain CAL12_RS26785 d50f26442aa5d4e4f4b50ffc0f600282 91 Pfam PF04359 Protein of unknown function (DUF493) 8 91 3.5E-28 T 06-07-2017 IPR007454 Uncharacterised protein family UPF0250 CAL12_RS26785 d50f26442aa5d4e4f4b50ffc0f600282 91 SUPERFAMILY SSF117991 7 91 3.53E-25 T 06-07-2017 IPR027471 YbeD-like domain CAL12_RS26785 d50f26442aa5d4e4f4b50ffc0f600282 91 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 3 91 20.864 T 06-07-2017 IPR007454 Uncharacterised protein family UPF0250 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 Pfam PF01799 [2Fe-2S] binding domain 73 145 7.3E-30 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 SUPERFAMILY SSF54292 2 78 1.28E-23 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 SUPERFAMILY SSF47741 84 152 9.29E-31 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 57 2.2E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 Gene3D G3DSA:1.10.150.120 75 152 5.0E-34 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS10345 e00fd963d766d1e817ac7d49baca09e7 156 Gene3D G3DSA:3.10.20.30 2 74 4.6E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS19140 c821b1605ea2a4d306d7a0ad12fb67a5 461 Pfam PF12801 4Fe-4S binding domain 65 103 4.6E-8 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS19140 c821b1605ea2a4d306d7a0ad12fb67a5 461 Pfam PF12801 4Fe-4S binding domain 161 188 2.6E-4 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS25665 04ab01319f77b90552fe016682f16807 128 SUPERFAMILY SSF51182 11 118 1.16E-26 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS25665 04ab01319f77b90552fe016682f16807 128 Pfam PF07883 Cupin domain 48 115 3.2E-18 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS25665 04ab01319f77b90552fe016682f16807 128 Gene3D G3DSA:2.60.120.10 23 122 2.1E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 SUPERFAMILY SSF52540 62 270 4.07E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 SUPERFAMILY SSF52540 1027 1227 4.07E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 SMART SM00968 578 685 2.7E-11 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Pfam PF06470 SMC proteins Flexible Hinge Domain 581 682 2.9E-8 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Gene3D G3DSA:1.10.287.1040 306 366 9.2E-4 T 06-07-2017 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 SUPERFAMILY SSF75553 553 733 3.14E-11 T 06-07-2017 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 62 1225 0.0 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Pfam PF02463 RecF/RecN/SMC N terminal domain 63 1218 6.6E-64 T 06-07-2017 IPR003395 RecF/RecN/SMC, N-terminal CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 PIRSF PIRSF005719 60 1234 1.6E-254 T 06-07-2017 IPR024704 Structural maintenance of chromosomes protein CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Hamap MF_01894 Chromosome partition protein Smc [smc]. 61 1227 22.312 T 06-07-2017 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Gene3D G3DSA:3.40.50.300 1075 1229 2.1E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19565 119c3dd42678827f6f5243b2892c5d45 1236 Gene3D G3DSA:3.40.50.300 62 226 2.1E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 30 213 5.9E-18 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 Gene3D G3DSA:3.40.50.720 29 189 6.3E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 31 50 5.2E-12 T 06-07-2017 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 5.2E-12 T 06-07-2017 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 5.2E-12 T 06-07-2017 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 Gene3D G3DSA:3.50.50.60 190 340 5.3E-6 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 179 204 2.8E-11 T 06-07-2017 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 30 52 2.8E-11 T 06-07-2017 CAL12_RS01215 be85d39c30bda520a01d2fe47e1501cd 455 SUPERFAMILY SSF51905 30 338 5.67E-31 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10505 80d5fd633a9eb721ae91409bf6244e49 156 Gene3D G3DSA:3.30.1330.40 4 152 4.1E-56 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS10505 80d5fd633a9eb721ae91409bf6244e49 156 SUPERFAMILY SSF55298 4 153 1.57E-49 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS10505 80d5fd633a9eb721ae91409bf6244e49 156 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 8 147 7.5E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS16785 6d54f8984d3d6e203e70dbb0aa114b83 180 SMART SM00347 63 161 9.4E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS16785 6d54f8984d3d6e203e70dbb0aa114b83 180 SUPERFAMILY SSF46785 46 172 5.62E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16785 6d54f8984d3d6e203e70dbb0aa114b83 180 Gene3D G3DSA:1.10.10.10 45 173 5.9E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16785 6d54f8984d3d6e203e70dbb0aa114b83 180 ProSitePatterns PS01117 MarR-type HTH domain signature. 100 134 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS16785 6d54f8984d3d6e203e70dbb0aa114b83 180 Pfam PF01047 MarR family 70 125 2.2E-8 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 156 173 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 35 44 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 85 102 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 194 208 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 4 22 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 PRINTS PR00395 Ribosomal protein S2 signature 173 184 2.0E-35 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 Pfam PF00318 Ribosomal protein S2 7 222 4.9E-90 T 06-07-2017 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 SUPERFAMILY SSF52313 4 227 3.01E-91 T 06-07-2017 IPR023591 Ribosomal protein S2, flavodoxin-like domain CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 4 15 - T 06-07-2017 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 38.824 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 1.5E-97 T 06-07-2017 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 Gene3D G3DSA:3.40.50.10490 21 97 3.0E-61 T 06-07-2017 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 Gene3D G3DSA:3.40.50.10490 156 230 3.0E-61 T 06-07-2017 CAL12_RS12115 fb83b540a38c77989f8e9ce66620e827 249 Gene3D G3DSA:1.10.287.610 98 150 5.8E-21 T 06-07-2017 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 Gene3D G3DSA:1.10.10.60 7 77 2.9E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 Pfam PF02954 Bacterial regulatory protein, Fis family 38 72 6.4E-16 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 1.4E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 1.4E-11 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 SUPERFAMILY SSF46689 10 77 1.21E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS05595 6c10d43b20ca81ae8b13d0a09fb7d56a 79 PIRSF PIRSF002097 1 78 1.6E-27 T 06-07-2017 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 SUPERFAMILY SSF53686 5 301 1.83E-85 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 39 57 - T 06-07-2017 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 Gene3D G3DSA:3.40.50.1100 49 150 1.7E-36 T 06-07-2017 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 302 4.3E-115 T 06-07-2017 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 8 302 3.6E-137 T 06-07-2017 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 Gene3D G3DSA:3.40.50.1100 5 48 1.4E-78 T 06-07-2017 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 Gene3D G3DSA:3.40.50.1100 156 302 1.4E-78 T 06-07-2017 CAL12_RS18885 a4b3f213649f3914183c036d0c6e49fb 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 291 2.0E-61 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS24925 a59ce06d7bbc7c942229c7224ea3183c 282 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 197 272 8.9E-11 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS24925 a59ce06d7bbc7c942229c7224ea3183c 282 SUPERFAMILY SSF74653 169 272 2.88E-14 T 06-07-2017 CAL12_RS24925 a59ce06d7bbc7c942229c7224ea3183c 282 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 197 270 5.2E-11 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS24925 a59ce06d7bbc7c942229c7224ea3183c 282 Gene3D G3DSA:3.30.1150.10 169 273 7.0E-19 T 06-07-2017 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 SUPERFAMILY SSF52540 20 276 8.32E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Gene3D G3DSA:3.40.50.300 335 588 6.8E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Gene3D G3DSA:3.40.50.300 13 283 6.8E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Pfam PF00005 ABC transporter 41 204 1.6E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Pfam PF00005 ABC transporter 364 513 9.7E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 566 603 1.3E-7 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 256 287 1.2E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 SMART SM00382 372 572 2.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 SMART SM00382 49 254 2.6E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08610 0aedcebec6594ce7a5be11356eb8e61a 643 SUPERFAMILY SSF52540 336 586 1.85E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 SMART SM00904 192 318 1.1E-50 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 PIRSF PIRSF004491 6 321 1.2E-91 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 Gene3D G3DSA:3.40.50.620 14 196 4.8E-62 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 317 5.2E-83 T 06-07-2017 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 Pfam PF06574 FAD synthetase 17 175 2.9E-49 T 06-07-2017 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 Gene3D G3DSA:2.40.30.30 197 318 5.4E-35 T 06-07-2017 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 Pfam PF01687 Riboflavin kinase 193 317 4.8E-33 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 SUPERFAMILY SSF82114 184 318 6.32E-37 T 06-07-2017 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CAL12_RS17290 4ca82430b39f767e2cea067cb8a40153 322 SUPERFAMILY SSF52374 18 184 1.26E-33 T 06-07-2017 CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 Gene3D G3DSA:1.20.1250.20 19 204 1.3E-25 T 06-07-2017 CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 SUPERFAMILY SSF103473 12 206 3.66E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 SUPERFAMILY SSF103473 259 430 3.66E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 SUPERFAMILY SSF103473 490 515 3.66E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 Gene3D G3DSA:1.20.1250.20 274 431 4.4E-17 T 06-07-2017 CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 Gene3D G3DSA:1.20.1250.20 491 517 4.4E-17 T 06-07-2017 CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 27 507 1.5E-103 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS13025 60e1ebab286c77339ec9be55805ffa58 526 Pfam PF07690 Major Facilitator Superfamily 27 420 2.7E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 SUPERFAMILY SSF51905 3 55 1.62E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 SUPERFAMILY SSF51905 354 398 1.62E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 SUPERFAMILY SSF51905 108 267 1.62E-44 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Gene3D G3DSA:3.30.9.10 253 352 6.5E-6 T 06-07-2017 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Gene3D G3DSA:3.50.50.60 354 397 1.3E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Gene3D G3DSA:3.50.50.60 186 252 1.3E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Gene3D G3DSA:3.50.50.60 109 131 1.3E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Gene3D G3DSA:3.50.50.60 3 59 1.3E-45 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 SUPERFAMILY SSF54373 269 354 2.35E-12 T 06-07-2017 CAL12_RS09785 ef93dde8a3ddf3903f0c4d50d4c332e5 400 Pfam PF01266 FAD dependent oxidoreductase 5 392 1.7E-56 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS18925 57a8b26d39191cb92c386500895bd7b6 244 Gene3D G3DSA:3.40.50.300 22 233 3.2E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18925 57a8b26d39191cb92c386500895bd7b6 244 Hamap MF_00238 Cytidylate kinase [cmk]. 22 236 32.617 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAL12_RS18925 57a8b26d39191cb92c386500895bd7b6 244 SUPERFAMILY SSF52540 22 234 1.75E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18925 57a8b26d39191cb92c386500895bd7b6 244 TIGRFAM TIGR00017 cmk: cytidylate kinase 22 230 1.3E-70 T 06-07-2017 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAL12_RS18925 57a8b26d39191cb92c386500895bd7b6 244 Pfam PF02224 Cytidylate kinase 24 231 2.0E-71 T 06-07-2017 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 CAL12_RS03925 926c6e49bbed01b7ef14e33e5e6dd88f 346 Pfam PF03595 Voltage-dependent anion channel 14 310 1.3E-37 T 06-07-2017 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 SUPERFAMILY SSF103515 887 914 1.01E-59 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 SUPERFAMILY SSF103515 944 1225 1.01E-59 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 Pfam PF03797 Autotransporter beta-domain 948 1209 1.1E-50 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 SMART SM00869 948 1215 1.2E-46 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 Gene3D G3DSA:2.40.128.130 948 1225 4.1E-59 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS14015 4652f0497b39ba0b47ab8c27cb4c0984 1225 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 658 1225 2.8E-43 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 SUPERFAMILY SSF53850 96 299 1.76E-42 T 06-07-2017 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 Pfam PF03466 LysR substrate binding domain 95 297 4.9E-47 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 Gene3D G3DSA:3.40.190.10 182 267 2.2E-22 T 06-07-2017 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 Gene3D G3DSA:3.40.190.10 96 181 9.3E-23 T 06-07-2017 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 SUPERFAMILY SSF46785 7 116 3.11E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 Gene3D G3DSA:1.10.10.10 7 87 3.1E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04365 9deb8e1abf4b217557cb7f650eaa835f 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 1.4E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS02480 5d9706facade23035c108f41a0c80ffb 478 Gene3D G3DSA:1.20.1250.20 267 459 9.4E-15 T 06-07-2017 CAL12_RS02480 5d9706facade23035c108f41a0c80ffb 478 Gene3D G3DSA:1.20.1250.20 15 194 8.5E-32 T 06-07-2017 CAL12_RS02480 5d9706facade23035c108f41a0c80ffb 478 SUPERFAMILY SSF103473 6 197 6.41E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02480 5d9706facade23035c108f41a0c80ffb 478 SUPERFAMILY SSF103473 248 459 6.41E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02480 5d9706facade23035c108f41a0c80ffb 478 Pfam PF07690 Major Facilitator Superfamily 20 409 7.2E-46 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16300 3eb656ee261bc7b5462f0611d2f25949 231 Gene3D G3DSA:1.10.3720.10 34 221 3.5E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16300 3eb656ee261bc7b5462f0611d2f25949 231 SUPERFAMILY SSF161098 32 213 4.45E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16300 3eb656ee261bc7b5462f0611d2f25949 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 52 221 9.1E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 Pfam PF07690 Major Facilitator Superfamily 259 445 1.4E-13 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 304 321 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 Pfam PF00083 Sugar (and other) transporter 26 246 2.7E-28 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 SUPERFAMILY SSF103473 22 436 1.31E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 Gene3D G3DSA:1.20.1250.20 259 435 9.6E-19 T 06-07-2017 CAL12_RS19090 613e78ac2421368db26e617769e4de52 449 Gene3D G3DSA:1.20.1250.20 23 231 3.0E-24 T 06-07-2017 CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 Gene3D G3DSA:1.10.10.60 170 218 2.2E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 SUPERFAMILY SSF52172 1 129 4.55E-39 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 Gene3D G3DSA:3.40.50.2300 1 125 9.3E-36 T 06-07-2017 CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 SUPERFAMILY SSF46689 161 217 8.51E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 SMART SM00448 2 114 2.5E-33 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26255 e1868d3aafa98a7817f7eacaf08c725b 225 Pfam PF00072 Response regulator receiver domain 4 114 2.5E-26 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS25745 287ab64474064853f7c31f19282a77bf 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 280 1.9E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25745 287ab64474064853f7c31f19282a77bf 302 Gene3D G3DSA:1.10.3720.10 103 286 3.3E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25745 287ab64474064853f7c31f19282a77bf 302 SUPERFAMILY SSF161098 101 286 2.62E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 ProSitePatterns PS00211 ABC transporters family signature. 478 492 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 Pfam PF00664 ABC transporter transmembrane region 20 294 3.2E-43 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 SUPERFAMILY SSF90123 8 328 1.7E-64 T 06-07-2017 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 Gene3D G3DSA:1.20.1560.10 6 322 7.0E-70 T 06-07-2017 CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 SUPERFAMILY SSF52540 331 576 1.38E-92 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 SMART SM00382 366 552 5.5E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 Gene3D G3DSA:3.40.50.300 341 570 7.2E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10055 1cd47d9f246b3bc567d8fa276cf24e90 598 Pfam PF00005 ABC transporter 357 506 9.9E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 3.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 3.0E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 SUPERFAMILY SSF46689 5 83 1.23E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 55 2.5E-10 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 SUPERFAMILY SSF48498 77 190 2.22E-26 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS16530 48bd97fd68803ebf1aa90472b78bc6a0 216 Gene3D G3DSA:1.10.357.10 6 190 1.6E-38 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS06700 54244e0ed273641f12da3eef03617701 400 Gene3D G3DSA:2.120.10.30 47 398 6.3E-126 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS06700 54244e0ed273641f12da3eef03617701 400 SUPERFAMILY SSF63829 252 397 5.56E-25 T 06-07-2017 CAL12_RS06700 54244e0ed273641f12da3eef03617701 400 SUPERFAMILY SSF63829 51 220 5.56E-25 T 06-07-2017 CAL12_RS06700 54244e0ed273641f12da3eef03617701 400 Pfam PF03022 Major royal jelly protein 116 371 9.0E-35 T 06-07-2017 IPR017996 Major royal jelly protein/protein yellow CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 Gene3D G3DSA:3.30.390.10 3 100 8.9E-13 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 SMART SM00922 132 228 3.7E-21 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 Gene3D G3DSA:3.20.20.120 101 335 3.0E-44 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 SUPERFAMILY SSF51604 123 336 9.69E-39 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 SUPERFAMILY SSF54826 3 104 4.12E-10 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS05100 1702c894e3cce22e5ab27940be7b73b6 358 Pfam PF13378 Enolase C-terminal domain-like 135 336 9.6E-31 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS23970 0e50bf3347c98abd1060b777f23c65d1 86 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 71 3.0E-27 T 06-07-2017 IPR021074 Formate dehydrogenase, delta subunit CAL12_RS14410 02f93fac727fb02f4cad28926ff7be9f 188 Pfam PF01965 DJ-1/PfpI family 9 177 4.8E-48 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS14410 02f93fac727fb02f4cad28926ff7be9f 188 SUPERFAMILY SSF52317 9 180 5.4E-43 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS14410 02f93fac727fb02f4cad28926ff7be9f 188 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 179 6.1E-48 T 06-07-2017 IPR006286 Peptidase C56, PfpI CAL12_RS14410 02f93fac727fb02f4cad28926ff7be9f 188 Gene3D G3DSA:3.40.50.880 3 186 4.9E-53 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS27245 098b83b1b9f5580982c29aa57b06d502 131 SUPERFAMILY SSF69118 4 124 1.44E-35 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS27245 098b83b1b9f5580982c29aa57b06d502 131 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 118 9.4E-25 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS27245 098b83b1b9f5580982c29aa57b06d502 131 Gene3D G3DSA:1.20.1290.10 11 125 2.6E-25 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.0E-15 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 SUPERFAMILY SSF53850 90 308 1.24E-43 T 06-07-2017 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Gene3D G3DSA:3.40.190.10 90 172 1.2E-33 T 06-07-2017 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Gene3D G3DSA:3.40.190.10 284 311 1.2E-33 T 06-07-2017 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 SUPERFAMILY SSF46785 2 84 3.99E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Pfam PF03466 LysR substrate binding domain 104 307 2.0E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Gene3D G3DSA:3.40.190.10 173 279 1.4E-28 T 06-07-2017 CAL12_RS24550 5892943e90f222ddedab753b4e47b2a0 321 Gene3D G3DSA:1.10.10.10 1 85 4.5E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20225 6351e9ff1bab46a687f078d0717814cd 296 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 50 267 4.6E-30 T 06-07-2017 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 CAL12_RS02875 59642f586a17fd69e28d16c142d90f66 497 SUPERFAMILY SSF53649 47 470 1.89E-109 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS02875 59642f586a17fd69e28d16c142d90f66 497 Gene3D G3DSA:3.40.720.10 47 408 3.3E-100 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS02875 59642f586a17fd69e28d16c142d90f66 497 Gene3D G3DSA:3.30.1120.10 409 474 1.8E-6 T 06-07-2017 CAL12_RS02875 59642f586a17fd69e28d16c142d90f66 497 Pfam PF14707 C-terminal region of aryl-sulfatase 394 474 6.0E-8 T 06-07-2017 CAL12_RS02875 59642f586a17fd69e28d16c142d90f66 497 Pfam PF00884 Sulfatase 49 370 1.3E-60 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS19240 ab8b5002284e303235205089199c0e77 242 Pfam PF00805 Pentapeptide repeats (8 copies) 193 227 7.8E-7 T 06-07-2017 IPR001646 Pentapeptide repeat CAL12_RS19240 ab8b5002284e303235205089199c0e77 242 SUPERFAMILY SSF141571 174 237 4.05E-10 T 06-07-2017 CAL12_RS15890 3c679ddab1503980b4f1f2a86e516d3c 145 SUPERFAMILY SSF46785 17 124 9.6E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15890 3c679ddab1503980b4f1f2a86e516d3c 145 Gene3D G3DSA:1.10.10.10 13 123 1.1E-39 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15890 3c679ddab1503980b4f1f2a86e516d3c 145 Pfam PF01638 HxlR-like helix-turn-helix 25 112 6.3E-27 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 Pfam PF08345 Flagellar M-ring protein C-terminal 254 447 2.5E-48 T 06-07-2017 IPR013556 Flagellar M-ring C-terminal CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PIRSF PIRSF004862 1 558 1.4E-151 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 Pfam PF01514 Secretory protein of YscJ/FliF family 33 222 6.5E-76 T 06-07-2017 IPR006182 Secretory protein YscJ/FliF CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PRINTS PR01009 Flagellar M-ring protein signature 198 216 7.0E-39 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PRINTS PR01009 Flagellar M-ring protein signature 375 399 7.0E-39 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PRINTS PR01009 Flagellar M-ring protein signature 123 141 7.0E-39 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PRINTS PR01009 Flagellar M-ring protein signature 267 285 7.0E-39 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 PRINTS PR01009 Flagellar M-ring protein signature 155 169 7.0E-39 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS12025 f29b181ff869d4c3d4b58e89647f95ff 558 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 12 557 4.6E-129 T 06-07-2017 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CAL12_RS10555 64c6e8f3a0454eac43b4c2acc890e883 330 PIRSF PIRSF017082 1 330 1.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10555 64c6e8f3a0454eac43b4c2acc890e883 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 326 1.8E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10555 64c6e8f3a0454eac43b4c2acc890e883 330 SUPERFAMILY SSF53850 115 291 1.54E-13 T 06-07-2017 CAL12_RS04580 7f9d1ddb926ab5bc34f083ad4f0ae4b6 900 Pfam PF13954 PapC N-terminal domain 41 191 1.4E-45 T 06-07-2017 IPR025885 PapC, N-terminal domain GO:0005515 CAL12_RS04580 7f9d1ddb926ab5bc34f083ad4f0ae4b6 900 SUPERFAMILY SSF141729 39 169 4.84E-33 T 06-07-2017 CAL12_RS04580 7f9d1ddb926ab5bc34f083ad4f0ae4b6 900 Pfam PF13953 PapC C-terminal domain 795 856 2.1E-20 T 06-07-2017 IPR025949 PapC-like, C-terminal domain CAL12_RS04580 7f9d1ddb926ab5bc34f083ad4f0ae4b6 900 Pfam PF00577 Outer membrane usher protein 206 785 1.5E-166 T 06-07-2017 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS04580 7f9d1ddb926ab5bc34f083ad4f0ae4b6 900 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 336 346 - T 06-07-2017 IPR018030 Fimbrial membrane usher, conserved site CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 Pfam PF09383 NIL domain 274 345 1.7E-12 T 06-07-2017 IPR018449 NIL domain CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 Gene3D G3DSA:3.30.70.260 238 349 1.8E-18 T 06-07-2017 CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 Gene3D G3DSA:3.40.50.300 1 237 5.1E-87 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 SMART SM00930 272 347 1.9E-12 T 06-07-2017 IPR018449 NIL domain CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 Pfam PF00005 ABC transporter 21 169 2.5E-32 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 SUPERFAMILY SSF52540 1 239 7.86E-84 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 SUPERFAMILY SSF55021 271 349 8.01E-12 T 06-07-2017 CAL12_RS22195 5da1434cc38f7affb96b733d0eea5faf 363 SMART SM00382 30 217 9.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02885 339516c0909aec28cfca4d6a44ab3821 398 SUPERFAMILY SSF103473 14 391 1.31E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02885 339516c0909aec28cfca4d6a44ab3821 398 Gene3D G3DSA:1.20.1250.20 213 387 2.1E-14 T 06-07-2017 CAL12_RS02885 339516c0909aec28cfca4d6a44ab3821 398 Gene3D G3DSA:1.20.1250.20 15 192 5.7E-14 T 06-07-2017 CAL12_RS02885 339516c0909aec28cfca4d6a44ab3821 398 Pfam PF07690 Major Facilitator Superfamily 267 386 3.7E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS02885 339516c0909aec28cfca4d6a44ab3821 398 Pfam PF07690 Major Facilitator Superfamily 19 247 1.7E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 SMART SM00922 147 237 1.2E-17 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 Pfam PF13378 Enolase C-terminal domain-like 155 354 1.4E-57 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 SUPERFAMILY SSF54826 1 129 1.77E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 Gene3D G3DSA:3.20.20.120 134 361 9.3E-62 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 187 218 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 Gene3D G3DSA:3.30.390.10 2 133 9.2E-39 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 SUPERFAMILY SSF51604 116 361 1.24E-63 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 128 1.8E-17 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS00385 9c9fba65642f3b7c83c2d8d77609e1e0 372 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 103 128 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS23475 ca8d8cfc1accf110a537d982cfd4a35b 325 Gene3D G3DSA:1.10.3720.10 90 315 3.3E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23475 ca8d8cfc1accf110a537d982cfd4a35b 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 320 1.5E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23475 ca8d8cfc1accf110a537d982cfd4a35b 325 SUPERFAMILY SSF161098 92 307 1.31E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 3.3E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 SUPERFAMILY SSF46785 12 93 6.76E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 Gene3D G3DSA:1.10.10.10 10 88 6.2E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 Gene3D G3DSA:3.40.190.10 98 207 8.5E-17 T 06-07-2017 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 SUPERFAMILY SSF53850 98 304 7.12E-23 T 06-07-2017 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 71 1.3E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18210 ca179d801c51716a34110d710c4e948a 307 Pfam PF03466 LysR substrate binding domain 96 300 3.8E-21 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 Gene3D G3DSA:3.30.70.100 257 342 1.0E-8 T 06-07-2017 CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 SUPERFAMILY SSF82689 256 354 1.96E-15 T 06-07-2017 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 Pfam PF00924 Mechanosensitive ion channel 148 344 1.7E-44 T 06-07-2017 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 Gene3D G3DSA:2.30.30.60 203 252 2.3E-13 T 06-07-2017 CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 SUPERFAMILY SSF50182 187 252 3.04E-12 T 06-07-2017 IPR010920 LSM domain CAL12_RS23840 5c5c76a422e217e7763c08024e7abaa3 386 SUPERFAMILY SSF82861 99 186 9.68E-12 T 06-07-2017 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 SMART SM00345 22 84 2.5E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 SUPERFAMILY SSF48008 106 243 6.02E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 Gene3D G3DSA:1.10.10.10 9 76 3.9E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 Pfam PF07729 FCD domain 108 236 1.6E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 SMART SM00895 108 238 1.2E-17 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 Gene3D G3DSA:1.20.120.530 105 244 1.8E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 76 6.4E-18 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 SUPERFAMILY SSF46785 15 76 1.09E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 1.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23215 9ba744c3023ae008030c91dadbbe46ae 283 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 1.2E-8 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS05900 059ea4b43bf5dcbc4deddf3bbd25f977 421 Gene3D G3DSA:1.20.1250.20 8 185 4.6E-28 T 06-07-2017 CAL12_RS05900 059ea4b43bf5dcbc4deddf3bbd25f977 421 Gene3D G3DSA:1.20.1250.20 214 401 8.0E-16 T 06-07-2017 CAL12_RS05900 059ea4b43bf5dcbc4deddf3bbd25f977 421 SUPERFAMILY SSF103473 6 395 1.96E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05900 059ea4b43bf5dcbc4deddf3bbd25f977 421 Pfam PF07690 Major Facilitator Superfamily 14 358 1.1E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 Gene3D G3DSA:3.40.50.1820 2 263 8.8E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 9.6E-12 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 Pfam PF12697 Alpha/beta hydrolase family 24 247 1.1E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS27600 af942101acc6698797bd4f1811c477e9 266 SUPERFAMILY SSF53474 1 263 1.91E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14625 4d5e8dc5bfffd7732f199b21d2c6187b 349 Gene3D G3DSA:3.60.130.10 56 346 1.1E-37 T 06-07-2017 CAL12_RS14625 4d5e8dc5bfffd7732f199b21d2c6187b 349 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 98 338 3.6E-27 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS14625 4d5e8dc5bfffd7732f199b21d2c6187b 349 SUPERFAMILY SSF51197 53 347 7.46E-47 T 06-07-2017 CAL12_RS22635 d46f58a90c35b976df3b0780fd9c0053 385 SUPERFAMILY SSF74653 293 375 1.09E-13 T 06-07-2017 CAL12_RS22635 d46f58a90c35b976df3b0780fd9c0053 385 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 311 381 4.3E-13 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS22635 d46f58a90c35b976df3b0780fd9c0053 385 Gene3D G3DSA:3.30.1150.10 275 382 1.2E-21 T 06-07-2017 CAL12_RS22635 d46f58a90c35b976df3b0780fd9c0053 385 Pfam PF13103 TonB C terminal 296 373 3.7E-13 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS22635 d46f58a90c35b976df3b0780fd9c0053 385 TIGRFAM TIGR02794 tolA_full: protein TolA 22 374 5.4E-57 T 06-07-2017 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 CAL12_RS09815 e0092006160b832085e0978cef681977 305 SUPERFAMILY SSF161098 88 286 2.09E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09815 e0092006160b832085e0978cef681977 305 Gene3D G3DSA:1.10.3720.10 87 300 1.2E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09815 e0092006160b832085e0978cef681977 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 303 1.8E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 Pfam PF14698 Argininosuccinate lyase C-terminal 402 478 3.8E-13 T 06-07-2017 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00149 Fumarate lyase superfamily signature 265 292 1.5E-8 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 1.5E-8 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.5E-8 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00149 Fumarate lyase superfamily signature 311 327 1.5E-8 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 Gene3D G3DSA:1.20.200.10 139 408 3.0E-52 T 06-07-2017 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 Gene3D G3DSA:1.10.40.30 409 479 1.4E-14 T 06-07-2017 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 Pfam PF00206 Lyase 134 329 4.5E-28 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 SUPERFAMILY SSF48557 66 503 6.75E-73 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 1.7E-15 T 06-07-2017 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00145 Argininosuccinate lyase family signature 225 241 1.7E-15 T 06-07-2017 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00145 Argininosuccinate lyase family signature 133 155 1.7E-15 T 06-07-2017 CAL12_RS24375 01de6d3db7f735cb4399511497cfd3b2 539 PRINTS PR00145 Argininosuccinate lyase family signature 311 327 1.7E-15 T 06-07-2017 CAL12_RS21265 86b0caf6956eba657089ddac3b0a0410 423 Gene3D G3DSA:2.40.50.100 174 207 4.6E-19 T 06-07-2017 CAL12_RS21265 86b0caf6956eba657089ddac3b0a0410 423 Gene3D G3DSA:2.40.50.100 66 99 4.6E-19 T 06-07-2017 CAL12_RS21265 86b0caf6956eba657089ddac3b0a0410 423 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 295 1.1E-11 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS21265 86b0caf6956eba657089ddac3b0a0410 423 SUPERFAMILY SSF111369 55 302 5.36E-80 T 06-07-2017 CAL12_RS21265 86b0caf6956eba657089ddac3b0a0410 423 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 376 2.1E-82 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS03165 5ecc2b996b3036d8522fa8a18e89cd85 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 275 9.0E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03165 5ecc2b996b3036d8522fa8a18e89cd85 280 Gene3D G3DSA:1.10.3720.10 69 271 3.0E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03165 5ecc2b996b3036d8522fa8a18e89cd85 280 SUPERFAMILY SSF161098 71 257 1.16E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03165 5ecc2b996b3036d8522fa8a18e89cd85 280 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 5 51 8.2E-13 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS11030 3a1773a8d2830972f5d11395805fc5df 245 SUPERFAMILY SSF53474 5 230 7.9E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11030 3a1773a8d2830972f5d11395805fc5df 245 Gene3D G3DSA:3.40.50.1820 4 231 1.8E-29 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11030 3a1773a8d2830972f5d11395805fc5df 245 Pfam PF00975 Thioesterase domain 7 226 3.1E-37 T 06-07-2017 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 SMART SM01134 74 235 4.3E-71 T 06-07-2017 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 SMART SM00420 6 58 6.2E-12 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 Gene3D G3DSA:3.30.750.70 78 163 4.6E-12 T 06-07-2017 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 SUPERFAMILY SSF46785 2 64 6.3E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 Pfam PF00455 DeoR C terminal sensor domain 76 233 7.4E-52 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 SUPERFAMILY SSF100950 76 237 3.65E-26 T 06-07-2017 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 Gene3D G3DSA:1.10.10.10 1 58 4.9E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 6.8E-14 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.8E-7 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.8E-7 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS10990 f6dbcb88f459a641cc175c9807a25606 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAL12_RS22780 04be59129e13181d9b2b1870d18091a0 325 Pfam PF04116 Fatty acid hydroxylase superfamily 135 275 7.6E-32 T 06-07-2017 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 CAL12_RS19640 8b252784435bed18b98bcea96b395804 110 Pfam PF10993 Protein of unknown function (DUF2818) 6 102 7.9E-35 T 06-07-2017 IPR016768 Uncharacterised conserved protein UCP019883, membrane CAL12_RS19640 8b252784435bed18b98bcea96b395804 110 PIRSF PIRSF019883 1 106 1.9E-42 T 06-07-2017 IPR016768 Uncharacterised conserved protein UCP019883, membrane CAL12_RS27910 b8e58c856c441f71bf205aff4fee8cb5 310 Gene3D G3DSA:1.10.3720.10 100 306 8.5E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27910 b8e58c856c441f71bf205aff4fee8cb5 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 307 3.3E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27910 b8e58c856c441f71bf205aff4fee8cb5 310 SUPERFAMILY SSF161098 102 293 8.5E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27910 b8e58c856c441f71bf205aff4fee8cb5 310 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 77 2.6E-10 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS10455 594b28a34c3055e928bfb1fcb4996134 71 Gene3D G3DSA:3.40.50.880 8 68 1.8E-6 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS00710 e3f356ec5d88aec655cb9a48f6219bf6 453 SUPERFAMILY SSF52540 110 158 6.61E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00710 e3f356ec5d88aec655cb9a48f6219bf6 453 SUPERFAMILY SSF52540 4 72 6.61E-18 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00710 e3f356ec5d88aec655cb9a48f6219bf6 453 Gene3D G3DSA:3.40.50.300 5 158 1.6E-22 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00710 e3f356ec5d88aec655cb9a48f6219bf6 453 Pfam PF11981 Domain of unknown function (DUF3482) 164 449 3.3E-95 T 06-07-2017 IPR021871 Protein of unknown function DUF3482 CAL12_RS00710 e3f356ec5d88aec655cb9a48f6219bf6 453 Pfam PF01926 50S ribosome-binding GTPase 6 151 3.6E-16 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS24200 892b658946a6e90a6eb8704f3310d5eb 148 SUPERFAMILY SSF55961 3 144 1.16E-43 T 06-07-2017 CAL12_RS24200 892b658946a6e90a6eb8704f3310d5eb 148 Gene3D G3DSA:3.30.530.20 4 144 3.5E-44 T 06-07-2017 IPR023393 START-like domain CAL12_RS24200 892b658946a6e90a6eb8704f3310d5eb 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 143 1.6E-30 T 06-07-2017 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 Pfam PF02203 Tar ligand binding domain homologue 4 171 2.7E-18 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 Gene3D G3DSA:1.20.120.30 97 176 1.6E-5 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 Gene3D G3DSA:1.10.287.950 299 503 8.7E-65 T 06-07-2017 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 SMART SM00283 284 531 3.0E-98 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 339 530 1.3E-64 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 Pfam PF00672 HAMP domain 212 279 8.8E-14 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 7.1E-64 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 488 7.1E-64 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 7.1E-64 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 7.1E-64 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 7.1E-64 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 SUPERFAMILY SSF47170 56 171 1.1E-10 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 SMART SM00304 231 283 2.6E-11 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11835 6e82750763f3e052ed5efbf6e50c5559 558 SUPERFAMILY SSF58104 251 533 1.18E-77 T 06-07-2017 CAL12_RS02750 1959f6dd19e9f15fe8a946fbf7b212d9 256 SUPERFAMILY SSF51735 2 220 1.59E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02750 1959f6dd19e9f15fe8a946fbf7b212d9 256 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 158 3.2E-17 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS02750 1959f6dd19e9f15fe8a946fbf7b212d9 256 Gene3D G3DSA:3.40.50.720 2 160 2.1E-30 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26640 5e996aa9f0a5b0a1e9e744557e690f44 213 SUPERFAMILY SSF52016 2 189 1.02E-48 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS26640 5e996aa9f0a5b0a1e9e744557e690f44 213 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 4 183 4.2E-54 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS26640 5e996aa9f0a5b0a1e9e744557e690f44 213 Pfam PF00694 Aconitase C-terminal domain 5 119 8.4E-29 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS26640 5e996aa9f0a5b0a1e9e744557e690f44 213 Gene3D G3DSA:3.20.19.10 2 191 6.0E-37 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Gene3D G3DSA:3.30.70.260 353 422 1.8E-11 T 06-07-2017 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 SUPERFAMILY SSF55021 353 422 1.37E-13 T 06-07-2017 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 PIRSF PIRSF000098 1 433 5.6E-161 T 06-07-2017 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Gene3D G3DSA:3.30.360.10 149 299 6.5E-56 T 06-07-2017 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Pfam PF01842 ACT domain 354 416 4.3E-13 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 1.4E-19 T 06-07-2017 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Pfam PF00742 Homoserine dehydrogenase 137 315 1.8E-64 T 06-07-2017 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 SUPERFAMILY SSF55347 137 302 2.03E-52 T 06-07-2017 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 06-07-2017 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CAL12_RS18225 aae588248483c6245e65631414a64d48 434 Gene3D G3DSA:3.40.50.720 1 148 7.9E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18225 aae588248483c6245e65631414a64d48 434 SUPERFAMILY SSF51735 1 158 6.29E-34 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 06-07-2017 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 SMART SM00411 1 90 5.6E-39 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.2E-33 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 SUPERFAMILY SSF47729 1 90 2.65E-32 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 Gene3D G3DSA:4.10.520.10 1 90 1.1E-36 T 06-07-2017 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 8.7E-19 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 8.7E-19 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS17575 a2a0f9fb0f38d3fe33940b5c5f46481e 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 8.7E-19 T 06-07-2017 IPR000119 Histone-like DNA-binding protein GO:0003677 CAL12_RS15915 c2379c4d3ba22eb3153e5b0ced182698 314 Gene3D G3DSA:1.10.3720.10 88 304 3.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15915 c2379c4d3ba22eb3153e5b0ced182698 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 2.2E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15915 c2379c4d3ba22eb3153e5b0ced182698 314 SUPERFAMILY SSF161098 90 296 5.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24305 c09af986d74dbab5b9f1acb76c53a9a4 303 Gene3D G3DSA:1.10.3720.10 96 299 1.7E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24305 c09af986d74dbab5b9f1acb76c53a9a4 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 290 5.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24305 c09af986d74dbab5b9f1acb76c53a9a4 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 79 4.0E-7 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS24305 c09af986d74dbab5b9f1acb76c53a9a4 303 SUPERFAMILY SSF161098 99 284 1.57E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24935 dfbb5923a1daaa35d6a5d040dc22795b 244 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 23 243 2.2E-84 T 06-07-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CAL12_RS24935 dfbb5923a1daaa35d6a5d040dc22795b 244 Pfam PF00912 Transglycosylase 68 238 1.9E-52 T 06-07-2017 IPR001264 Glycosyl transferase, family 51 CAL12_RS24935 dfbb5923a1daaa35d6a5d040dc22795b 244 Gene3D G3DSA:1.10.3810.10 69 240 3.5E-65 T 06-07-2017 CAL12_RS24935 dfbb5923a1daaa35d6a5d040dc22795b 244 SUPERFAMILY SSF53955 68 242 4.78E-57 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS24935 dfbb5923a1daaa35d6a5d040dc22795b 244 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 16 244 40.408 T 06-07-2017 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 Pfam PF00106 short chain dehydrogenase 9 191 8.3E-52 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 3.9E-5 T 06-07-2017 CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 SUPERFAMILY SSF51735 5 234 1.82E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.3E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.3E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.3E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.3E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.3E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.5E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS04405 3a4c79df84c159ad7ff176b5d1f1fde1 291 Gene3D G3DSA:3.40.50.720 4 221 2.3E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Pfam PF00005 ABC transporter 303 436 1.4E-22 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Pfam PF00005 ABC transporter 22 152 1.6E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 SMART SM00382 31 197 7.3E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 SMART SM00382 311 481 9.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 SUPERFAMILY SSF52540 6 200 1.05E-48 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 SUPERFAMILY SSF52540 279 475 1.39E-47 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Pfam PF12848 ABC transporter 191 267 1.2E-9 T 06-07-2017 IPR032781 ABC-transporter extension domain CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Pfam PF16326 ABC transporter C-terminal domain 537 606 9.3E-16 T 06-07-2017 IPR032524 ABC transporter Uup, C-terminal GO:0003677 CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Gene3D G3DSA:3.40.50.300 6 224 8.1E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS22470 e99c8e344d8039ebe84267adf7dd5a74 612 Gene3D G3DSA:3.40.50.300 288 477 1.2E-44 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 Gene3D G3DSA:1.10.287.90 29 112 7.2E-34 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 PIRSF PIRSF000292 1 319 7.6E-128 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 SUPERFAMILY SSF49503 130 289 8.37E-50 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 SUPERFAMILY SSF81464 30 117 9.32E-23 T 06-07-2017 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 Pfam PF06481 COX Aromatic Rich Motif 249 291 2.4E-16 T 06-07-2017 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 Gene3D G3DSA:2.60.40.420 132 288 1.1E-40 T 06-07-2017 IPR008972 Cupredoxin CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 158 228 1.0E-7 T 06-07-2017 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS21275 2fca11488b69d0a84d183b6e3d33d5ed 358 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 15 246 6.3E-109 T 06-07-2017 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 CAL12_RS03020 80e59e0cc99170bf2de58b9c81c1c79d 203 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 58 186 3.7E-32 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS13985 75f20cec535da355d7726b1c1dd22cbd 332 PIRSF PIRSF017082 1 332 8.5E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13985 75f20cec535da355d7726b1c1dd22cbd 332 SUPERFAMILY SSF53850 118 293 1.21E-13 T 06-07-2017 CAL12_RS13985 75f20cec535da355d7726b1c1dd22cbd 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 328 2.2E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Gene3D G3DSA:3.30.300.30 445 549 5.1E-33 T 06-07-2017 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Gene3D G3DSA:3.40.50.980 37 194 1.1E-34 T 06-07-2017 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Pfam PF00501 AMP-binding enzyme 38 446 4.1E-81 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 SUPERFAMILY SSF56801 7 548 2.62E-145 T 06-07-2017 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Gene3D G3DSA:3.40.50.980 195 356 1.4E-24 T 06-07-2017 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Gene3D G3DSA:2.30.38.10 357 436 3.5E-22 T 06-07-2017 CAL12_RS08675 977ab07fb8177f9dc4414d3ce23185dc 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 535 5.3E-22 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS17795 c37c8c413a6e1efbe18024a03a282ccb 122 SUPERFAMILY SSF81273 80 121 6.28E-11 T 06-07-2017 CAL12_RS17795 c37c8c413a6e1efbe18024a03a282ccb 122 Gene3D G3DSA:4.10.430.10 79 121 2.6E-13 T 06-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CAL12_RS17795 c37c8c413a6e1efbe18024a03a282ccb 122 Pfam PF00816 H-NS histone family 13 114 2.0E-24 T 06-07-2017 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 CAL12_RS17795 c37c8c413a6e1efbe18024a03a282ccb 122 SMART SM00528 77 121 4.8E-15 T 06-07-2017 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 CAL12_RS18535 2de94b676673396a03fcbf6b0dd2872a 225 Pfam PF11010 Protein of unknown function (DUF2848) 24 216 6.1E-82 T 06-07-2017 IPR021269 Protein of unknown function DUF2848 CAL12_RS18535 2de94b676673396a03fcbf6b0dd2872a 225 SUPERFAMILY SSF56529 36 205 1.98E-10 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 SUPERFAMILY SSF46785 1 84 6.65E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 Gene3D G3DSA:3.40.190.10 88 173 4.6E-20 T 06-07-2017 CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 Pfam PF03466 LysR substrate binding domain 88 293 5.6E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 SUPERFAMILY SSF53850 91 294 1.86E-28 T 06-07-2017 CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 Gene3D G3DSA:3.40.190.10 174 265 9.4E-15 T 06-07-2017 CAL12_RS06075 d537fadc4ef1906549e8c3683cda0f69 305 Gene3D G3DSA:1.10.10.10 1 80 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07650 df0a1d4f34808fb274a31d8e6bbfd807 354 SUPERFAMILY SSF53850 82 313 2.34E-14 T 06-07-2017 CAL12_RS07650 df0a1d4f34808fb274a31d8e6bbfd807 354 PIRSF PIRSF017082 27 353 5.9E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07650 df0a1d4f34808fb274a31d8e6bbfd807 354 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 78 347 1.3E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 Pfam PF12833 Helix-turn-helix domain 184 260 2.0E-19 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 Gene3D G3DSA:1.10.10.60 157 214 8.2E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 SMART SM00342 178 260 1.2E-13 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 Gene3D G3DSA:2.60.120.10 29 96 2.3E-12 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 Gene3D G3DSA:1.10.10.60 219 259 2.4E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 Pfam PF02311 AraC-like ligand binding domain 33 105 5.4E-7 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 SUPERFAMILY SSF51182 29 187 1.63E-17 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS06655 4e9de6a0febd5f9dff797bae18a38df8 283 SUPERFAMILY SSF46689 218 262 2.28E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS02555 a36c3c250db5bc22a74a8d471524e09e 144 SUPERFAMILY SSF51182 17 121 9.5E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS02555 a36c3c250db5bc22a74a8d471524e09e 144 Pfam PF07883 Cupin domain 50 119 7.1E-17 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS02555 a36c3c250db5bc22a74a8d471524e09e 144 Gene3D G3DSA:2.60.120.10 11 120 9.9E-25 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 407 512 8.7E-15 T 06-07-2017 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 379 389 - T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 Pfam PF01266 FAD dependent oxidoreductase 26 385 2.7E-51 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 99 111 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 374 386 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 25 37 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 48 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 54 66 5.3E-29 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 Gene3D G3DSA:3.50.50.60 25 266 1.5E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS10985 13bd6ffb42f8b4538faf86616d71c461 532 SUPERFAMILY SSF51905 25 351 3.02E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 Gene3D G3DSA:3.40.50.1000 16 91 3.4E-40 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 Gene3D G3DSA:3.40.50.1000 167 245 3.4E-40 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 15 245 5.3E-45 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 SUPERFAMILY SSF56784 17 244 1.7E-42 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 212 5.0E-19 T 06-07-2017 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CAL12_RS08960 ff8e4ac806d7a6d5f461bf0036383b0c 245 Pfam PF02358 Trehalose-phosphatase 19 225 7.7E-42 T 06-07-2017 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CAL12_RS07125 523146c8c8f2b8e1f6d37dceea898165 395 Gene3D G3DSA:3.30.1540.10 233 315 1.0E-32 T 06-07-2017 CAL12_RS07125 523146c8c8f2b8e1f6d37dceea898165 395 Gene3D G3DSA:3.40.50.10540 316 390 9.6E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS07125 523146c8c8f2b8e1f6d37dceea898165 395 Gene3D G3DSA:3.40.50.10540 4 227 9.6E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS07125 523146c8c8f2b8e1f6d37dceea898165 395 SUPERFAMILY SSF89796 4 389 4.32E-134 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS07125 523146c8c8f2b8e1f6d37dceea898165 395 Pfam PF02515 CoA-transferase family III 6 382 1.0E-126 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS26230 a74b439bf78f90f191f202c6b2875987 265 Gene3D G3DSA:3.40.50.2020 139 254 5.2E-22 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS26230 a74b439bf78f90f191f202c6b2875987 265 SUPERFAMILY SSF53271 61 94 3.95E-22 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS26230 a74b439bf78f90f191f202c6b2875987 265 SUPERFAMILY SSF53271 134 254 3.95E-22 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS26230 a74b439bf78f90f191f202c6b2875987 265 Pfam PF00156 Phosphoribosyl transferase domain 214 255 7.9E-7 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS09230 a75ef07bfb1b6d257b5c7dd25751e597 212 SUPERFAMILY SSF48452 98 190 2.11E-6 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS09230 a75ef07bfb1b6d257b5c7dd25751e597 212 Pfam PF09976 Tetratricopeptide repeat-like domain 15 210 1.3E-55 T 06-07-2017 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038 CAL12_RS09230 a75ef07bfb1b6d257b5c7dd25751e597 212 PIRSF PIRSF006170 1 212 6.7E-53 T 06-07-2017 IPR026039 Uncharacterised protein family UPF0070 CAL12_RS08795 ec51823b88af61bb9dc2af37627d7a48 421 PIRSF PIRSF003085 4 412 4.3E-129 T 06-07-2017 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CAL12_RS08795 ec51823b88af61bb9dc2af37627d7a48 421 SUPERFAMILY SSF53335 121 391 1.48E-69 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08795 ec51823b88af61bb9dc2af37627d7a48 421 Gene3D G3DSA:3.40.50.150 109 389 4.8E-88 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS08795 ec51823b88af61bb9dc2af37627d7a48 421 Pfam PF02353 Mycolic acid cyclopropane synthetase 110 387 1.5E-94 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS23855 c5afbd2d061cf44007198298cdd0c00f 434 Gene3D G3DSA:1.20.1250.20 247 419 2.5E-12 T 06-07-2017 CAL12_RS23855 c5afbd2d061cf44007198298cdd0c00f 434 Gene3D G3DSA:1.20.1250.20 23 217 9.9E-27 T 06-07-2017 CAL12_RS23855 c5afbd2d061cf44007198298cdd0c00f 434 SUPERFAMILY SSF103473 1 424 6.02E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23855 c5afbd2d061cf44007198298cdd0c00f 434 Pfam PF07690 Major Facilitator Superfamily 37 394 2.2E-37 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS17625 9b7281d6b4f296d908ed54647e017e2c 553 PIRSF PIRSF006429 6 543 3.1E-162 T 06-07-2017 IPR024188 Glutamate synthase large subunit-like protein CAL12_RS17625 9b7281d6b4f296d908ed54647e017e2c 553 PIRSF PIRSF500060 11 531 1.2E-240 T 06-07-2017 IPR027283 Glutamate synthase large subunit-like protein, bacteria CAL12_RS17625 9b7281d6b4f296d908ed54647e017e2c 553 Gene3D G3DSA:3.20.20.70 50 492 1.0E-123 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS17625 9b7281d6b4f296d908ed54647e017e2c 553 SUPERFAMILY SSF51395 25 498 1.83E-141 T 06-07-2017 CAL12_RS17625 9b7281d6b4f296d908ed54647e017e2c 553 Pfam PF01645 Conserved region in glutamate synthase 158 474 8.5E-85 T 06-07-2017 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 Gene3D G3DSA:1.10.10.60 267 314 1.6E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 Pfam PF12833 Helix-turn-helix domain 234 313 5.5E-24 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 Gene3D G3DSA:1.10.10.60 221 266 5.4E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 SUPERFAMILY SSF52317 7 194 6.55E-45 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 SMART SM00342 228 311 4.0E-27 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 Gene3D G3DSA:3.40.50.880 8 220 9.6E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 SUPERFAMILY SSF46689 216 261 1.66E-10 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 280 295 1.2E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 295 311 1.2E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 Pfam PF01965 DJ-1/PfpI family 11 173 1.1E-17 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 307 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS10695 07dec79b184b7f6a9e6bd63503de0917 320 SUPERFAMILY SSF46689 265 315 3.81E-11 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 1.2E-162 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 8.9E-156 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 369 2.3E-90 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 SUPERFAMILY SSF51713 4 371 2.49E-156 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 367 56.203 T 06-07-2017 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS04930 b8f5df2d436ad58d207ee68bfded5dc1 378 Gene3D G3DSA:3.20.20.105 3 373 1.9E-164 T 06-07-2017 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 37 96 4.8E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 SUPERFAMILY SSF53850 124 328 9.62E-32 T 06-07-2017 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 Pfam PF03466 LysR substrate binding domain 122 324 1.7E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 73 2.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 2.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 73 84 2.8E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 Gene3D G3DSA:3.40.190.10 124 209 7.0E-17 T 06-07-2017 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 Gene3D G3DSA:1.10.10.10 35 117 2.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 Gene3D G3DSA:3.40.190.10 210 293 1.4E-13 T 06-07-2017 CAL12_RS12315 6852a303e336130d1017265388f2dc1f 338 SUPERFAMILY SSF46785 32 144 1.43E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Pfam PF05199 GMC oxidoreductase 406 520 5.0E-16 T 06-07-2017 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Gene3D G3DSA:3.50.50.60 377 390 5.3E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Gene3D G3DSA:3.50.50.60 218 315 5.3E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Gene3D G3DSA:3.50.50.60 6 141 5.3E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Gene3D G3DSA:3.50.50.60 458 526 5.3E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 SUPERFAMILY SSF51905 466 527 1.54E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 SUPERFAMILY SSF51905 5 313 1.54E-58 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 385 7.6E-5 T 06-07-2017 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 7.6E-5 T 06-07-2017 CAL12_RS13700 f9eb8c18194aa2c9db45794b0971614a 529 Pfam PF00732 GMC oxidoreductase 8 314 1.3E-13 T 06-07-2017 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CAL12_RS22360 072097168dec6aa8109c112443a0fd01 244 Pfam PF13468 Glyoxalase-like domain 10 186 5.7E-31 T 06-07-2017 IPR025870 Glyoxalase-like domain CAL12_RS22360 072097168dec6aa8109c112443a0fd01 244 Gene3D G3DSA:3.10.180.10 5 106 5.5E-9 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS22360 072097168dec6aa8109c112443a0fd01 244 SUPERFAMILY SSF54593 1 118 4.13E-12 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS03215 6ed2433a375c50715926851dbeced971 292 Pfam PF01261 Xylose isomerase-like TIM barrel 38 244 1.3E-23 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS03215 6ed2433a375c50715926851dbeced971 292 Gene3D G3DSA:3.20.20.150 11 289 4.5E-50 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS03215 6ed2433a375c50715926851dbeced971 292 SUPERFAMILY SSF51658 11 288 2.88E-48 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS21530 8fb959afb4f15c67bb13b8c1b01f27ab 376 Gene3D G3DSA:3.40.50.10540 7 220 2.1E-103 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS21530 8fb959afb4f15c67bb13b8c1b01f27ab 376 Gene3D G3DSA:3.40.50.10540 309 371 2.1E-103 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS21530 8fb959afb4f15c67bb13b8c1b01f27ab 376 Gene3D G3DSA:3.30.1540.10 226 308 3.4E-30 T 06-07-2017 CAL12_RS21530 8fb959afb4f15c67bb13b8c1b01f27ab 376 SUPERFAMILY SSF89796 8 366 6.54E-126 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS21530 8fb959afb4f15c67bb13b8c1b01f27ab 376 Pfam PF02515 CoA-transferase family III 10 365 1.4E-119 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 Gene3D G3DSA:2.40.50.100 207 239 4.8E-10 T 06-07-2017 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 Gene3D G3DSA:2.40.50.100 54 77 4.8E-10 T 06-07-2017 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 Pfam PF13437 HlyD family secretion protein 210 321 3.2E-14 T 06-07-2017 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 SUPERFAMILY SSF111369 54 133 4.97E-7 T 06-07-2017 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 Pfam PF13533 Biotin-lipoyl like 44 92 6.2E-10 T 06-07-2017 CAL12_RS02910 1172e8909438dc69bdeec6459ad9dbec 339 SUPERFAMILY SSF111369 149 327 1.96E-9 T 06-07-2017 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 128 2.6E-26 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 Pfam PF03652 Holliday junction resolvase 5 128 1.2E-33 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 SUPERFAMILY SSF53098 5 129 6.83E-33 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 131 20.688 T 06-07-2017 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 Gene3D G3DSA:3.30.420.140 4 129 1.6E-36 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAL12_RS24955 6ffa1192261108e7d6344bd697c0c7d1 132 SMART SM00732 4 104 1.5E-24 T 06-07-2017 IPR006641 YqgF/RNase H-like domain GO:0006139 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 Gene3D G3DSA:3.30.43.10 1 54 2.6E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 Gene3D G3DSA:3.30.465.10 59 173 4.7E-29 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 Gene3D G3DSA:3.30.390.50 179 276 7.5E-4 T 06-07-2017 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 4.2E-43 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 SUPERFAMILY SSF56176 4 173 1.23E-46 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS12870 f8772cddc12e8106a182097250c713e7 280 SUPERFAMILY SSF55447 180 274 7.85E-6 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS06545 a5bbba4fcecce7edf35d02628d58ca7c 213 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 8 209 31.268 T 06-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CAL12_RS06545 a5bbba4fcecce7edf35d02628d58ca7c 213 SUPERFAMILY SSF53335 27 209 2.11E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS06545 a5bbba4fcecce7edf35d02628d58ca7c 213 Gene3D G3DSA:3.40.50.150 3 211 4.6E-68 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS06545 a5bbba4fcecce7edf35d02628d58ca7c 213 PIRSF PIRSF005461 1 212 3.6E-68 T 06-07-2017 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 CAL12_RS06545 a5bbba4fcecce7edf35d02628d58ca7c 213 Pfam PF01728 FtsJ-like methyltransferase 28 207 2.6E-54 T 06-07-2017 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CAL12_RS14020 2ae2db9e5b3dc4c3d87815905ac6159b 83 Pfam PF05532 CsbD-like 3 53 6.5E-14 T 06-07-2017 IPR008462 CsbD-like CAL12_RS14020 2ae2db9e5b3dc4c3d87815905ac6159b 83 SUPERFAMILY SSF69047 3 55 5.62E-12 T 06-07-2017 IPR008462 CsbD-like CAL12_RS14020 2ae2db9e5b3dc4c3d87815905ac6159b 83 Gene3D G3DSA:1.10.1470.10 3 55 5.8E-15 T 06-07-2017 IPR008462 CsbD-like CAL12_RS16340 2e50bfc5e38f9004583ca13d8d246cf4 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 263 2.8E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16340 2e50bfc5e38f9004583ca13d8d246cf4 270 SUPERFAMILY SSF161098 6 269 1.4E-62 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16340 2e50bfc5e38f9004583ca13d8d246cf4 270 Gene3D G3DSA:1.10.3720.10 6 259 1.2E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 Pfam PF00009 Elongation factor Tu GTP binding domain 16 218 2.3E-37 T 06-07-2017 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 Gene3D G3DSA:2.40.30.10 233 360 7.7E-25 T 06-07-2017 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 SUPERFAMILY SSF50465 329 431 6.71E-27 T 06-07-2017 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 17 431 1.6E-159 T 06-07-2017 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 SUPERFAMILY SSF50447 233 323 2.5E-20 T 06-07-2017 IPR009000 Translation protein, beta-barrel domain CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 06-07-2017 IPR031157 Tr-type G domain, conserved site CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.0E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.0E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 PRINTS PR00315 GTP-binding elongation factor signature 78 86 1.0E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 PRINTS PR00315 GTP-binding elongation factor signature 98 108 1.0E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 PRINTS PR00315 GTP-binding elongation factor signature 114 125 1.0E-14 T 06-07-2017 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 Gene3D G3DSA:3.40.50.300 14 230 3.5E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18730 34b9c41224e004823fbfae74cb5bb7ad 432 SUPERFAMILY SSF52540 16 248 7.0E-52 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 Gene3D G3DSA:3.30.450.40 113 271 2.3E-37 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 Pfam PF01614 Bacterial transcriptional regulator 154 271 4.6E-23 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 Gene3D G3DSA:1.10.10.10 34 102 1.6E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 SUPERFAMILY SSF46785 34 102 5.77E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 SUPERFAMILY SSF55781 113 273 4.05E-33 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS03390 b6d380d4e4bf643cd12b4c7468d53da8 278 Pfam PF09339 IclR helix-turn-helix domain 34 82 3.6E-13 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS09170 275e5808d6a36bd8a028ef52c8d943ae 344 Pfam PF04917 Bacterial shufflon protein, N-terminal constant region 226 278 3.7E-7 T 06-07-2017 IPR007001 Bacterial shufflon protein, N-terminal CAL12_RS13530 e69f0ab42d21540d24a5d4f859c37030 225 SUPERFAMILY SSF53448 2 207 1.77E-29 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS13530 e69f0ab42d21540d24a5d4f859c37030 225 Gene3D G3DSA:3.90.550.10 2 207 1.8E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS13530 e69f0ab42d21540d24a5d4f859c37030 225 Pfam PF00535 Glycosyl transferase family 2 4 125 1.8E-13 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS16205 4757f424d9db3073db483e7faf31c959 233 Pfam PF02230 Phospholipase/Carboxylesterase 14 205 1.8E-29 T 06-07-2017 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 CAL12_RS16205 4757f424d9db3073db483e7faf31c959 233 SUPERFAMILY SSF53474 15 208 1.54E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16205 4757f424d9db3073db483e7faf31c959 233 Gene3D G3DSA:3.40.50.1820 14 214 9.0E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS04000 0511d02a4770ed0e9495cf7ca1e4b841 272 Pfam PF00005 ABC transporter 21 179 4.2E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS04000 0511d02a4770ed0e9495cf7ca1e4b841 272 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS04000 0511d02a4770ed0e9495cf7ca1e4b841 272 Gene3D G3DSA:3.40.50.300 2 253 2.6E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04000 0511d02a4770ed0e9495cf7ca1e4b841 272 SUPERFAMILY SSF52540 1 251 1.11E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04000 0511d02a4770ed0e9495cf7ca1e4b841 272 SMART SM00382 30 229 3.2E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12460 2536a9469b804a9232c23465b09ef419 147 Gene3D G3DSA:3.30.530.20 2 144 1.2E-39 T 06-07-2017 IPR023393 START-like domain CAL12_RS12460 2536a9469b804a9232c23465b09ef419 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 143 1.7E-23 T 06-07-2017 IPR019587 Polyketide cyclase/dehydrase CAL12_RS12460 2536a9469b804a9232c23465b09ef419 147 SUPERFAMILY SSF55961 1 143 2.31E-33 T 06-07-2017 CAL12_RS23145 24541d5410b02c4af4c240f2a0c84948 406 Pfam PF10129 OpgC protein 26 385 3.1E-77 T 06-07-2017 IPR014550 Uncharacterised conserved protein UCP028704, OpgC CAL12_RS23145 24541d5410b02c4af4c240f2a0c84948 406 PIRSF PIRSF028704 5 396 1.2E-54 T 06-07-2017 IPR014550 Uncharacterised conserved protein UCP028704, OpgC CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 SUPERFAMILY SSF52343 204 338 1.19E-38 T 06-07-2017 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Pfam PF00970 Oxidoreductase FAD-binding domain 105 201 3.4E-13 T 06-07-2017 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Pfam PF00175 Oxidoreductase NAD-binding domain 213 318 5.9E-21 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 6.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 6.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 237 246 6.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 6.3E-6 T 06-07-2017 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 81 8.7E-16 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Gene3D G3DSA:2.40.30.10 102 203 1.1E-28 T 06-07-2017 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 SUPERFAMILY SSF54292 1 89 3.41E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 SUPERFAMILY SSF63380 102 203 1.04E-20 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Gene3D G3DSA:3.40.50.80 205 339 4.8E-39 T 06-07-2017 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 Gene3D G3DSA:3.10.20.30 2 93 7.5E-30 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS09120 18b91776340e2d517918d7ee36e09484 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 1.5E-22 T 06-07-2017 IPR001221 Phenol hydroxylase reductase GO:0055114 CAL12_RS08770 8536ae8b38b91410c902dd2046dbc06c 523 Gene3D G3DSA:3.40.309.10 265 453 3.2E-53 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS08770 8536ae8b38b91410c902dd2046dbc06c 523 Pfam PF00171 Aldehyde dehydrogenase family 14 454 1.3E-44 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08770 8536ae8b38b91410c902dd2046dbc06c 523 Gene3D G3DSA:3.40.605.10 4 263 2.7E-48 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08770 8536ae8b38b91410c902dd2046dbc06c 523 SUPERFAMILY SSF53720 16 509 1.44E-102 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS26505 5e9451d1906ee56f50c4045bc8ea2e8c 464 Pfam PF07005 Putative sugar-binding N-terminal domain 11 254 8.4E-54 T 06-07-2017 IPR010737 Putative sugar-binding, N-terminal domain CAL12_RS26505 5e9451d1906ee56f50c4045bc8ea2e8c 464 SUPERFAMILY SSF142764 11 453 1.01E-81 T 06-07-2017 CAL12_RS26505 5e9451d1906ee56f50c4045bc8ea2e8c 464 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 293 450 6.4E-23 T 06-07-2017 IPR031475 Putative nucleotide-binding C-terminal domain CAL12_RS11650 08e1a1f64a3c19d2d1e84118cd45726e 326 PIRSF PIRSF017082 1 326 2.2E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11650 08e1a1f64a3c19d2d1e84118cd45726e 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 3.8E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11650 08e1a1f64a3c19d2d1e84118cd45726e 326 SUPERFAMILY SSF53850 117 291 8.21E-10 T 06-07-2017 CAL12_RS00320 95362322abbc802bf9a0c1a5deeb43e7 260 Pfam PF00005 ABC transporter 21 181 6.3E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS00320 95362322abbc802bf9a0c1a5deeb43e7 260 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 234 251 2.8E-6 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS00320 95362322abbc802bf9a0c1a5deeb43e7 260 SMART SM00382 29 237 1.2E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00320 95362322abbc802bf9a0c1a5deeb43e7 260 Gene3D G3DSA:3.40.50.300 2 250 1.1E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS00320 95362322abbc802bf9a0c1a5deeb43e7 260 SUPERFAMILY SSF52540 4 251 7.94E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19725 bf239a71e094ee480c1551157994b74d 500 Gene3D G3DSA:3.90.76.10 32 183 5.0E-35 T 06-07-2017 CAL12_RS19725 bf239a71e094ee480c1551157994b74d 500 SUPERFAMILY SSF53850 15 494 2.93E-132 T 06-07-2017 CAL12_RS19725 bf239a71e094ee480c1551157994b74d 500 Gene3D G3DSA:3.10.105.10 256 468 4.0E-53 T 06-07-2017 CAL12_RS19725 bf239a71e094ee480c1551157994b74d 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 417 2.2E-86 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS19725 bf239a71e094ee480c1551157994b74d 500 PIRSF PIRSF002741 9 497 3.1E-106 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS22990 e3f7424e0ee033d6d937a2a47357ddbf 327 SUPERFAMILY SSF53448 5 246 6.28E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS22990 e3f7424e0ee033d6d937a2a47357ddbf 327 Gene3D G3DSA:3.90.550.10 7 232 3.0E-44 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS22990 e3f7424e0ee033d6d937a2a47357ddbf 327 Pfam PF00535 Glycosyl transferase family 2 10 126 2.8E-26 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS17610 a518f0dcd0486e7e9e800469f6944bab 145 SUPERFAMILY SSF55729 1 143 3.19E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS17610 a518f0dcd0486e7e9e800469f6944bab 145 Gene3D G3DSA:3.40.630.30 19 141 2.0E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS17610 a518f0dcd0486e7e9e800469f6944bab 145 Pfam PF13673 Acetyltransferase (GNAT) domain 48 142 2.4E-22 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS14660 5420318cfdd6e4dafa92ffdb73529871 131 Gene3D G3DSA:1.10.10.10 74 130 7.5E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14660 5420318cfdd6e4dafa92ffdb73529871 131 SUPERFAMILY SSF46785 71 131 1.78E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14660 5420318cfdd6e4dafa92ffdb73529871 131 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 74 131 1.1E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11065 fb001e7d1f92e2527edb7dee0f5021f7 310 Gene3D G3DSA:3.40.50.1820 7 298 4.8E-94 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11065 fb001e7d1f92e2527edb7dee0f5021f7 310 SUPERFAMILY SSF53474 21 296 3.44E-73 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11065 fb001e7d1f92e2527edb7dee0f5021f7 310 Pfam PF07859 alpha/beta hydrolase fold 68 274 1.6E-73 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 Gene3D G3DSA:2.40.290.10 48 157 1.4E-6 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 Pfam PF02735 Ku70/Ku80 beta-barrel domain 14 180 1.9E-32 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 TIGRFAM TIGR02772 Ku_bact: Ku protein 5 267 1.6E-90 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 4 265 30.714 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 SMART SM00559 55 183 9.7E-26 T 06-07-2017 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571 CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 SUPERFAMILY SSF100939 5 270 2.94E-48 T 06-07-2017 IPR016194 SPOC-like, C-terminal domain CAL12_RS07235 d4ee6196f5f4b17b4d4fc767875b4892 310 PIRSF PIRSF006493 2 302 1.4E-90 T 06-07-2017 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CAL12_RS20540 227ab56021d22d9672944e72d649e8a5 266 Gene3D G3DSA:3.20.20.60 3 223 8.0E-58 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS20540 227ab56021d22d9672944e72d649e8a5 266 SUPERFAMILY SSF51621 5 265 3.3E-58 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS20540 227ab56021d22d9672944e72d649e8a5 266 Pfam PF13714 Phosphoenolpyruvate phosphomutase 8 242 4.8E-66 T 06-07-2017 CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 SUPERFAMILY SSF51735 16 262 2.09E-68 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 4.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.1E-7 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 260 1.8E-54 T 06-07-2017 CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.6E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS07270 dc824ceb84d1ade9de7cef307140e335 265 Gene3D G3DSA:3.40.50.720 13 264 3.0E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 SUPERFAMILY SSF53067 393 482 6.24E-13 T 06-07-2017 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 SUPERFAMILY SSF53067 260 344 6.24E-13 T 06-07-2017 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 SUPERFAMILY SSF53067 1 78 6.24E-13 T 06-07-2017 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 181 1.1E-58 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 Gene3D G3DSA:3.30.420.40 1 66 1.7E-4 T 06-07-2017 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 Pfam PF01968 Hydantoinase/oxoprolinase 202 488 2.2E-95 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS01585 7f58fa0fc9b09550c1a4aebca7a9bb7b 685 Gene3D G3DSA:3.30.420.40 281 323 5.3E-4 T 06-07-2017 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 Gene3D G3DSA:3.90.1150.10 381 461 9.8E-6 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 Gene3D G3DSA:3.40.640.10 158 375 7.3E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 Pfam PF00155 Aminotransferase class I and II 151 465 4.3E-34 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 SUPERFAMILY SSF46785 16 94 1.53E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.2E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 SUPERFAMILY SSF53383 112 473 4.26E-80 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 SMART SM00345 24 83 5.0E-19 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 Gene3D G3DSA:1.10.10.10 22 90 4.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23990 d660009e2c3a78128400c875b54cb6d7 490 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 2.9E-17 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 183 7.6E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 Gene3D G3DSA:1.10.150.240 19 80 9.0E-7 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 179 4.4E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 Gene3D G3DSA:3.40.50.1000 3 18 3.6E-37 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 Gene3D G3DSA:3.40.50.1000 81 215 3.6E-37 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.1E-31 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 5 211 3.7E-50 T 06-07-2017 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CAL12_RS18970 497d99377cfa8bc1b5e2af0291fa7068 228 SUPERFAMILY SSF56784 4 216 1.49E-52 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 SUPERFAMILY SSF52540 6 435 1.13E-83 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 444 1.4E-201 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 444 42.673 T 06-07-2017 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 336 407 1.9E-5 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 SMART SM01086 336 432 2.2E-20 T 06-07-2017 IPR019489 Clp ATPase, C-terminal CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 104 1.5E-6 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Gene3D G3DSA:1.10.8.10 113 178 3.7E-28 T 06-07-2017 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Gene3D G3DSA:1.10.8.10 214 244 3.7E-28 T 06-07-2017 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Gene3D G3DSA:1.10.8.60 336 431 1.6E-31 T 06-07-2017 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 184 330 4.1E-40 T 06-07-2017 IPR003959 ATPase, AAA-type, core GO:0005524 CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Gene3D G3DSA:3.40.50.300 5 112 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 Gene3D G3DSA:3.40.50.300 246 332 2.3E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26745 51af26fdd7aedd191a46786fd635b6a6 444 SMART SM00382 51 333 2.5E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03095 5c887c6c0bc91afd3b25fa145cdb73fb 381 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 134 327 6.2E-11 T 06-07-2017 IPR005079 Peptidase C45 CAL12_RS15700 0e6dfda8230adaaed35ae46de27b4cbe 240 Pfam PF00005 ABC transporter 20 163 1.6E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15700 0e6dfda8230adaaed35ae46de27b4cbe 240 Gene3D G3DSA:3.40.50.300 3 235 2.7E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15700 0e6dfda8230adaaed35ae46de27b4cbe 240 SUPERFAMILY SSF52540 3 236 7.94E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15700 0e6dfda8230adaaed35ae46de27b4cbe 240 SMART SM00382 28 212 3.9E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15700 0e6dfda8230adaaed35ae46de27b4cbe 240 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 235 7.6E-11 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:3.30.70.1430 579 681 6.3E-28 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 575 681 1.46E-25 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 818 867 1.57E-26 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 682 731 1.57E-26 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82866 299 499 4.45E-52 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 277 333 5.23E-28 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 139 184 5.23E-28 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 2.1E-91 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82714 732 819 6.8E-20 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82714 185 274 7.98E-23 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:1.10.3850.10 825 1038 8.9E-60 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:1.10.3850.10 285 501 5.0E-63 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:3.30.70.1430 41 141 1.3E-31 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82866 841 1037 4.71E-47 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:3.30.2090.10 184 277 2.6E-28 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 Gene3D G3DSA:3.30.2090.10 732 820 5.0E-22 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 SUPERFAMILY SSF82693 41 134 2.44E-26 T 06-07-2017 CAL12_RS01920 a2785cb6450aef7133941454c029909b 1073 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1045 0.0 T 06-07-2017 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 CAL12_RS11280 44ffe2ff37e592b6c19caf91cee7b842 352 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 277 349 9.8E-10 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS02505 5e7ed4fb907cf54a0f6863f4484c1096 346 Pfam PF09084 NMT1/THI5 like 57 269 1.2E-23 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS02505 5e7ed4fb907cf54a0f6863f4484c1096 346 SUPERFAMILY SSF53850 45 279 4.41E-42 T 06-07-2017 CAL12_RS02505 5e7ed4fb907cf54a0f6863f4484c1096 346 SMART SM00062 47 268 0.0027 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS02505 5e7ed4fb907cf54a0f6863f4484c1096 346 Gene3D G3DSA:3.40.190.10 131 256 3.4E-20 T 06-07-2017 CAL12_RS23920 d65d0d3a749f52add0868fdf1516f324 164 SUPERFAMILY SSF54690 4 152 3.01E-46 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23920 d65d0d3a749f52add0868fdf1516f324 164 Pfam PF02391 MoaE protein 7 122 9.1E-34 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS23920 d65d0d3a749f52add0868fdf1516f324 164 Gene3D G3DSA:3.90.1170.40 3 149 7.5E-49 T 06-07-2017 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CAL12_RS12585 913274330c03cc304b56264733871843 295 SUPERFAMILY SSF46785 2 112 1.36E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12585 913274330c03cc304b56264733871843 295 SUPERFAMILY SSF53850 91 293 3.26E-48 T 06-07-2017 CAL12_RS12585 913274330c03cc304b56264733871843 295 Gene3D G3DSA:3.40.190.10 92 177 5.7E-25 T 06-07-2017 CAL12_RS12585 913274330c03cc304b56264733871843 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.3E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12585 913274330c03cc304b56264733871843 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12585 913274330c03cc304b56264733871843 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12585 913274330c03cc304b56264733871843 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.9E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12585 913274330c03cc304b56264733871843 295 Pfam PF03466 LysR substrate binding domain 90 292 1.3E-49 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS12585 913274330c03cc304b56264733871843 295 Gene3D G3DSA:1.10.10.10 2 80 1.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12585 913274330c03cc304b56264733871843 295 Gene3D G3DSA:3.40.190.10 178 264 1.9E-23 T 06-07-2017 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 Gene3D G3DSA:3.50.50.60 95 218 1.1E-10 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 Gene3D G3DSA:3.50.50.60 306 356 1.7E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 Gene3D G3DSA:3.50.50.60 219 260 1.7E-8 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 SUPERFAMILY SSF51905 290 404 2.59E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 SUPERFAMILY SSF51905 157 224 2.59E-12 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 SUPERFAMILY SSF51905 2 268 9.36E-20 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11080 849caaebd41e7fd65ce472ed8b777ba5 446 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 2 359 9.4E-125 T 06-07-2017 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CAL12_RS00640 3a6bedc7c372353815a628e15dfeb1dd 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 284 4.4E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00640 3a6bedc7c372353815a628e15dfeb1dd 287 Gene3D G3DSA:1.10.3720.10 56 283 3.1E-57 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00640 3a6bedc7c372353815a628e15dfeb1dd 287 SUPERFAMILY SSF161098 48 271 5.63E-59 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18055 faac602207c50376b37758fdf39ea291 269 SUPERFAMILY SSF161098 6 263 4.14E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18055 faac602207c50376b37758fdf39ea291 269 Gene3D G3DSA:1.10.3720.10 8 263 2.3E-54 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18055 faac602207c50376b37758fdf39ea291 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 261 6.4E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 9 199 2.1E-44 T 06-07-2017 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 SUPERFAMILY SSF82829 240 316 2.75E-19 T 06-07-2017 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 Pfam PF01171 PP-loop family 9 195 2.5E-48 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 308 21.334 T 06-07-2017 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 Gene3D G3DSA:3.40.50.620 8 168 1.4E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 Pfam PF09179 TilS substrate binding domain 247 315 1.2E-14 T 06-07-2017 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CAL12_RS07625 8f45ded68b30962813f31c0e1a1273b2 323 SUPERFAMILY SSF52402 7 228 8.38E-49 T 06-07-2017 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 PIRSF PIRSF000429 5 380 6.1E-35 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 Gene3D G3DSA:3.40.47.10 241 366 2.8E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 Gene3D G3DSA:3.40.47.10 141 181 2.8E-18 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 SUPERFAMILY SSF53901 241 371 7.0E-27 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 Pfam PF02803 Thiolase, C-terminal domain 245 360 1.8E-5 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 Gene3D G3DSA:3.40.47.10 196 223 2.6E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 Gene3D G3DSA:3.40.47.10 30 117 2.6E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01435 1c8926e68ccb63840c2b81d95721257f 385 SUPERFAMILY SSF53901 11 226 2.49E-26 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 Gene3D G3DSA:3.20.20.140 76 388 1.8E-111 T 06-07-2017 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 Gene3D G3DSA:2.30.40.10 11 75 1.7E-21 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 SUPERFAMILY SSF51338 370 466 1.27E-34 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 SUPERFAMILY SSF51338 11 88 1.03E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 Pfam PF01979 Amidohydrolase family 57 449 3.2E-26 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 Gene3D G3DSA:2.30.40.10 389 467 7.2E-15 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 13 467 6.0E-165 T 06-07-2017 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CAL12_RS23355 22158fd36a87eb22fb4ae65eedc792d1 508 SUPERFAMILY SSF51556 61 395 6.62E-103 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS21185 28bd5d76cf6b27ee5c54551d9c4a79d4 402 Gene3D G3DSA:1.20.1250.20 10 194 1.9E-17 T 06-07-2017 CAL12_RS21185 28bd5d76cf6b27ee5c54551d9c4a79d4 402 Pfam PF07690 Major Facilitator Superfamily 19 315 5.7E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21185 28bd5d76cf6b27ee5c54551d9c4a79d4 402 SUPERFAMILY SSF103473 6 386 6.15E-33 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10780 db05c8a39406468535e7b6469a26388a 296 SUPERFAMILY SSF103481 197 290 1.09E-7 T 06-07-2017 CAL12_RS10780 db05c8a39406468535e7b6469a26388a 296 Pfam PF00892 EamA-like transporter family 11 140 4.7E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS10780 db05c8a39406468535e7b6469a26388a 296 Pfam PF00892 EamA-like transporter family 155 284 1.5E-7 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS10780 db05c8a39406468535e7b6469a26388a 296 SUPERFAMILY SSF103481 47 143 3.27E-11 T 06-07-2017 CAL12_RS14195 17f318de013b7f72e8c09d8b2c4fc709 217 SUPERFAMILY SSF55469 1 216 1.31E-66 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS14195 17f318de013b7f72e8c09d8b2c4fc709 217 Pfam PF00881 Nitroreductase family 7 193 6.6E-28 T 06-07-2017 IPR029479 Nitroreductase Reactome: R-HSA-209968 CAL12_RS14195 17f318de013b7f72e8c09d8b2c4fc709 217 Gene3D G3DSA:3.40.109.10 1 216 9.6E-64 T 06-07-2017 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CAL12_RS04620 dd24e84b83937d13f8d4a3e00e4bc02a 448 Pfam PF07805 HipA-like N-terminal domain 151 231 1.9E-17 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAL12_RS04620 dd24e84b83937d13f8d4a3e00e4bc02a 448 Pfam PF13657 HipA N-terminal domain 6 105 1.8E-18 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS04620 dd24e84b83937d13f8d4a3e00e4bc02a 448 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 8 105 3.2E-19 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS04620 dd24e84b83937d13f8d4a3e00e4bc02a 448 Pfam PF07804 HipA-like C-terminal domain 247 399 3.2E-27 T 06-07-2017 IPR012893 HipA-like, C-terminal CAL12_RS19170 c2a86868c46ea4b87e37859cfcd05429 551 Gene3D G3DSA:3.40.50.1820 146 468 2.7E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19170 c2a86868c46ea4b87e37859cfcd05429 551 Gene3D G3DSA:3.40.50.1820 508 517 2.7E-34 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19170 c2a86868c46ea4b87e37859cfcd05429 551 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 20 548 1.1E-195 T 06-07-2017 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 CAL12_RS19170 c2a86868c46ea4b87e37859cfcd05429 551 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 47 213 1.9E-62 T 06-07-2017 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 CAL12_RS19170 c2a86868c46ea4b87e37859cfcd05429 551 SUPERFAMILY SSF53474 159 467 1.07E-37 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 PIRSF PIRSF000423 12 451 3.2E-183 T 06-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 SUPERFAMILY SSF53633 19 302 3.35E-61 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 22 451 2.5E-177 T 06-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 Gene3D G3DSA:3.40.1160.10 37 300 4.1E-57 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 Pfam PF00696 Amino acid kinase family 39 248 4.4E-29 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 Pfam PF00583 Acetyltransferase (GNAT) family 350 422 7.3E-7 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 SUPERFAMILY SSF55729 307 428 8.31E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 451 194.878 T 06-07-2017 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS18015 f74ccb71c01e7e98f7c8f9f3694198ec 451 Gene3D G3DSA:3.40.630.30 307 448 4.8E-35 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS02100 e914aa5cbef7858d5bbbbeaf9dd951b0 404 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 300 306 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS02100 e914aa5cbef7858d5bbbbeaf9dd951b0 404 Pfam PF01070 FMN-dependent dehydrogenase 37 401 1.2E-118 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS02100 e914aa5cbef7858d5bbbbeaf9dd951b0 404 Gene3D G3DSA:3.20.20.70 28 402 2.5E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS02100 e914aa5cbef7858d5bbbbeaf9dd951b0 404 SUPERFAMILY SSF51395 26 402 6.72E-87 T 06-07-2017 CAL12_RS02100 e914aa5cbef7858d5bbbbeaf9dd951b0 404 PIRSF PIRSF000138 13 404 2.0E-118 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS04810 db9edb189b7d8b32265bb5b5ddcd8ba0 100 Gene3D G3DSA:3.30.70.1060 2 87 2.8E-21 T 06-07-2017 CAL12_RS04810 db9edb189b7d8b32265bb5b5ddcd8ba0 100 SUPERFAMILY SSF54909 2 88 3.22E-20 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS04810 db9edb189b7d8b32265bb5b5ddcd8ba0 100 Pfam PF03795 YCII-related domain 2 87 6.4E-16 T 06-07-2017 IPR005545 YCII-related CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 Gene3D G3DSA:3.60.21.10 10 134 1.3E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 Gene3D G3DSA:3.60.21.10 185 238 1.3E-13 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 SUPERFAMILY SSF56300 9 131 4.66E-21 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 SUPERFAMILY SSF56300 187 217 4.66E-21 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 13 232 3.0E-61 T 06-07-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 Pfam PF00149 Calcineurin-like phosphoesterase 9 211 1.9E-6 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS07595 c388b23c9917c7fb4f3e7aa77c22f07c 259 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 259 91.231 T 06-07-2017 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 CAL12_RS12670 2b88a3020d181505f3b9d9d65f0e9979 436 Gene3D G3DSA:3.40.1060.10 151 243 1.4E-12 T 06-07-2017 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS12670 2b88a3020d181505f3b9d9d65f0e9979 436 Gene3D G3DSA:3.30.499.10 277 424 1.9E-39 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS12670 2b88a3020d181505f3b9d9d65f0e9979 436 SUPERFAMILY SSF53732 1 422 1.19E-90 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS12670 2b88a3020d181505f3b9d9d65f0e9979 436 Gene3D G3DSA:3.30.499.10 3 150 5.7E-16 T 06-07-2017 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS12670 2b88a3020d181505f3b9d9d65f0e9979 436 Pfam PF00330 Aconitase family (aconitate hydratase) 65 413 1.9E-51 T 06-07-2017 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS12170 8326bdbb0cb605849b721eeb66efcd35 152 Pfam PF07977 FabA-like domain 12 142 5.1E-42 T 06-07-2017 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS12170 8326bdbb0cb605849b721eeb66efcd35 152 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 147 4.6E-58 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS12170 8326bdbb0cb605849b721eeb66efcd35 152 SUPERFAMILY SSF54637 6 148 3.44E-49 T 06-07-2017 IPR029069 HotDog domain CAL12_RS12170 8326bdbb0cb605849b721eeb66efcd35 152 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 149 35.155 T 06-07-2017 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS12170 8326bdbb0cb605849b721eeb66efcd35 152 Gene3D G3DSA:3.10.129.10 2 148 4.5E-57 T 06-07-2017 IPR029069 HotDog domain CAL12_RS14840 070f1fbcdce9809365254f5235c6f041 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 39 277 1.0E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14840 070f1fbcdce9809365254f5235c6f041 315 PIRSF PIRSF017082 1 311 3.7E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14840 070f1fbcdce9809365254f5235c6f041 315 SUPERFAMILY SSF53850 106 276 1.36E-12 T 06-07-2017 CAL12_RS12215 00258209a105b81e178ec4fe2c5bb9d4 147 Gene3D G3DSA:2.40.50.140 84 137 7.5E-4 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS12215 00258209a105b81e178ec4fe2c5bb9d4 147 Pfam PF01957 NfeD-like C-terminal, partner-binding 3 137 1.1E-5 T 06-07-2017 IPR002810 NfeD-like, C-terminal domain CAL12_RS17285 18eaaa0d2f5d0d298a3658064422bd46 226 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 11 196 31.391 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAL12_RS17285 18eaaa0d2f5d0d298a3658064422bd46 226 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 198 4.0E-72 T 06-07-2017 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CAL12_RS17285 18eaaa0d2f5d0d298a3658064422bd46 226 SUPERFAMILY SSF53328 11 204 1.18E-63 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS17285 18eaaa0d2f5d0d298a3658064422bd46 226 Gene3D G3DSA:3.40.50.170 10 202 2.5E-69 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS17285 18eaaa0d2f5d0d298a3658064422bd46 226 Pfam PF00551 Formyl transferase 11 190 2.0E-56 T 06-07-2017 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CAL12_RS23320 46a847816d18c97b9e2bc3a2b6622783 313 Gene3D G3DSA:1.10.3720.10 90 309 2.5E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23320 46a847816d18c97b9e2bc3a2b6622783 313 SUPERFAMILY SSF161098 91 300 1.44E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23320 46a847816d18c97b9e2bc3a2b6622783 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 4.7E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 SUPERFAMILY SSF53822 46 400 1.8E-84 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 Gene3D G3DSA:3.40.50.2300 46 243 2.7E-46 T 06-07-2017 CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 Pfam PF13458 Periplasmic binding protein 60 389 4.3E-73 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 354 369 2.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 83 2.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS10735 c6bd6da4292628c54769feedba1e853c 418 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 86 104 2.2E-5 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS14805 23e3807614d85e8c73bb750e62136df8 297 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 88 292 2.1E-61 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14805 23e3807614d85e8c73bb750e62136df8 297 SUPERFAMILY SSF56529 81 292 1.24E-66 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14805 23e3807614d85e8c73bb750e62136df8 297 Gene3D G3DSA:3.90.850.10 73 293 5.5E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 Gene3D G3DSA:3.40.50.300 7 28 2.5E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 Gene3D G3DSA:3.40.50.300 77 184 2.5E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 8 183 3.0E-61 T 06-07-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 5 183 32.985 T 06-07-2017 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532 CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 SMART SM00072 6 186 1.2E-5 T 06-07-2017 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CAL12_RS05120 44a18b57c6c199fbb4eedffbeec0d791 187 SUPERFAMILY SSF52540 7 183 3.53E-28 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 1.1E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 SUPERFAMILY SSF46785 13 150 4.0E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 SMART SM00347 39 140 5.6E-22 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 Gene3D G3DSA:1.10.10.10 10 151 7.2E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 Pfam PF01047 MarR family 47 104 5.5E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25065 efbcfff8615a5c3f49b68fdc1213bef7 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS10755 740638016edd68d32abe24cd48aed889 2408 SMART SM00869 2133 2398 7.6E-24 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS10755 740638016edd68d32abe24cd48aed889 2408 SUPERFAMILY SSF103515 2109 2408 4.32E-33 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23890 9562582a64584237c5f7da2f9c359e9a 454 Gene3D G3DSA:1.20.1250.20 9 181 2.2E-13 T 06-07-2017 CAL12_RS23890 9562582a64584237c5f7da2f9c359e9a 454 Pfam PF00083 Sugar (and other) transporter 39 153 2.8E-6 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS23890 9562582a64584237c5f7da2f9c359e9a 454 SUPERFAMILY SSF103473 9 376 3.79E-41 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS23890 9562582a64584237c5f7da2f9c359e9a 454 Pfam PF07690 Major Facilitator Superfamily 206 382 1.1E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS23890 9562582a64584237c5f7da2f9c359e9a 454 Gene3D G3DSA:1.20.1250.20 197 380 8.4E-22 T 06-07-2017 CAL12_RS12790 c9d1236731e510df5b3df3a474468534 277 SUPERFAMILY SSF100950 9 263 1.12E-64 T 06-07-2017 CAL12_RS12790 c9d1236731e510df5b3df3a474468534 277 Pfam PF01144 Coenzyme A transferase 15 228 1.0E-23 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS12790 c9d1236731e510df5b3df3a474468534 277 SMART SM00882 11 231 5.3E-34 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS12790 c9d1236731e510df5b3df3a474468534 277 Gene3D G3DSA:3.40.1080.10 9 125 5.3E-71 T 06-07-2017 CAL12_RS12790 c9d1236731e510df5b3df3a474468534 277 Gene3D G3DSA:3.40.1080.10 163 259 5.3E-71 T 06-07-2017 CAL12_RS15855 58c91acae70cdaca7bd8d9ac009da9f6 322 SUPERFAMILY SSF53850 109 282 6.79E-16 T 06-07-2017 CAL12_RS15855 58c91acae70cdaca7bd8d9ac009da9f6 322 PIRSF PIRSF017082 1 320 4.1E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15855 58c91acae70cdaca7bd8d9ac009da9f6 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 316 2.5E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17490 7209c7cc98f41eeaee0e3d16b7b5ee16 345 Pfam PF02615 Malate/L-lactate dehydrogenase 2 324 2.9E-105 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS17490 7209c7cc98f41eeaee0e3d16b7b5ee16 345 SUPERFAMILY SSF89733 3 338 5.76E-94 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS17490 7209c7cc98f41eeaee0e3d16b7b5ee16 345 Gene3D G3DSA:1.10.1530.10 2 51 4.8E-14 T 06-07-2017 CAL12_RS17490 7209c7cc98f41eeaee0e3d16b7b5ee16 345 Gene3D G3DSA:3.30.1370.60 52 267 5.4E-75 T 06-07-2017 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 359 3.6E-53 T 06-07-2017 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 4 371 5.7E-180 T 06-07-2017 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 SMART SM00859 4 123 1.9E-25 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 373 32.699 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 Gene3D G3DSA:3.30.360.10 144 356 6.0E-68 T 06-07-2017 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 Gene3D G3DSA:3.40.50.720 4 143 1.8E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 SUPERFAMILY SSF51735 5 148 2.05E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 PIRSF PIRSF000148 2 376 1.1E-61 T 06-07-2017 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 267 281 - T 06-07-2017 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 122 6.6E-22 T 06-07-2017 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CAL12_RS09680 684cb4f0c91f24a2849915695c357acd 376 SUPERFAMILY SSF55347 135 360 3.99E-71 T 06-07-2017 CAL12_RS22730 9ca058a8e768be31693f94d77fb79de2 439 Pfam PF06812 ImpA, N-terminal, type VI secretion system 76 195 1.1E-29 T 06-07-2017 IPR010657 ImpA, N-terminal CAL12_RS22730 9ca058a8e768be31693f94d77fb79de2 439 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 68 413 2.4E-61 T 06-07-2017 IPR017740 Type VI secretion system-associated, ImpA CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 PIRSF PIRSF002741 3 529 6.8E-57 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 SUPERFAMILY SSF53850 31 523 1.65E-91 T 06-07-2017 CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 445 9.3E-62 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 Gene3D G3DSA:3.40.190.10 185 299 4.3E-24 T 06-07-2017 CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 Gene3D G3DSA:3.10.105.10 300 501 8.7E-25 T 06-07-2017 CAL12_RS23305 5a3452bdbc75605b99a84fe69c8bd3d6 529 Gene3D G3DSA:3.90.76.10 41 184 1.2E-27 T 06-07-2017 CAL12_RS19270 8820493f583ffc7923fee4d08047c8bc 137 PIRSF PIRSF000178 3 134 1.9E-25 T 06-07-2017 CAL12_RS19270 8820493f583ffc7923fee4d08047c8bc 137 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 9 131 4.3E-32 T 06-07-2017 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19270 8820493f583ffc7923fee4d08047c8bc 137 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 18 129 1.1E-26 T 06-07-2017 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS19270 8820493f583ffc7923fee4d08047c8bc 137 SUPERFAMILY SSF81343 6 133 5.67E-26 T 06-07-2017 CAL12_RS19270 8820493f583ffc7923fee4d08047c8bc 137 Gene3D G3DSA:1.20.1300.10 3 134 4.0E-33 T 06-07-2017 CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 06-07-2017 IPR018038 Ribosomal protein L30, conserved site CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 60 20.831 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 SUPERFAMILY SSF55129 4 61 2.62E-21 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 4.4E-19 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 Gene3D G3DSA:3.30.1390.20 4 61 2.4E-29 T 06-07-2017 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 PIRSF PIRSF002211 1 61 1.2E-27 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAL12_RS27535 eab57914c2851a76297e442b727995b7 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 60 1.5E-25 T 06-07-2017 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAL12_RS19400 adda9f9780b31d06528063124a412f54 204 SUPERFAMILY SSF53955 17 187 4.13E-24 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS19400 adda9f9780b31d06528063124a412f54 204 Gene3D G3DSA:1.10.530.10 51 163 7.5E-9 T 06-07-2017 CAL12_RS02870 a196178124d80a658315140738b1595c 305 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 30 301 1.2E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02870 a196178124d80a658315140738b1595c 305 PIRSF PIRSF017082 1 305 2.9E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02870 a196178124d80a658315140738b1595c 305 SUPERFAMILY SSF53850 93 267 4.34E-11 T 06-07-2017 CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 Gene3D G3DSA:3.40.50.720 2 248 2.7E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.3E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 SUPERFAMILY SSF51735 3 247 2.94E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS17465 65845f2d6bbc69a1dda984016c7031c7 252 Pfam PF00106 short chain dehydrogenase 6 195 1.8E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS08470 638d12794a422a145a7c5dfa6733d45d 123 Gene3D G3DSA:3.40.50.1010 1 117 9.7E-5 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS08470 638d12794a422a145a7c5dfa6733d45d 123 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 119 10.369 T 06-07-2017 IPR022907 VapC family GO:0004540 CAL12_RS08470 638d12794a422a145a7c5dfa6733d45d 123 SUPERFAMILY SSF88723 1 118 1.04E-16 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS08470 638d12794a422a145a7c5dfa6733d45d 123 Pfam PF01850 PIN domain 2 112 2.5E-7 T 06-07-2017 IPR002716 PIN domain CAL12_RS26185 eb178f341f392e9348e8eeb387f93c03 546 Pfam PF01551 Peptidase family M23 447 540 7.0E-27 T 06-07-2017 IPR016047 Peptidase M23 CAL12_RS26185 eb178f341f392e9348e8eeb387f93c03 546 Gene3D G3DSA:2.70.70.10 417 545 4.1E-36 T 06-07-2017 CAL12_RS26185 eb178f341f392e9348e8eeb387f93c03 546 SUPERFAMILY SSF51261 410 544 2.88E-44 T 06-07-2017 IPR011055 Duplicated hybrid motif CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 Pfam PF13458 Periplasmic binding protein 25 360 3.3E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 Gene3D G3DSA:3.40.50.2300 148 300 3.9E-38 T 06-07-2017 CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 SUPERFAMILY SSF53822 25 359 8.83E-83 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 Gene3D G3DSA:3.40.50.2300 301 356 6.4E-54 T 06-07-2017 CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 Gene3D G3DSA:3.40.50.2300 19 147 6.4E-54 T 06-07-2017 CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 2.3E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 279 292 2.3E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS24775 c90d768e0f41a6eb9bd17cdba4f68717 383 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 2.3E-11 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS05060 d19ade44006f4d034ff788705e690e72 59 Pfam PF11755 Protein of unknown function (DUF3311) 3 58 1.3E-22 T 06-07-2017 IPR021741 Protein of unknown function DUF3311 CAL12_RS18900 6e9e29398862ee9f85b3fee209324d26 312 SUPERFAMILY SSF53613 13 308 1.87E-60 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS18900 6e9e29398862ee9f85b3fee209324d26 312 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 11 309 1.9E-123 T 06-07-2017 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167 CAL12_RS18900 6e9e29398862ee9f85b3fee209324d26 312 Pfam PF00294 pfkB family carbohydrate kinase 13 302 1.8E-43 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAL12_RS18900 6e9e29398862ee9f85b3fee209324d26 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 52 75 - T 06-07-2017 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CAL12_RS18900 6e9e29398862ee9f85b3fee209324d26 312 Gene3D G3DSA:3.40.1190.20 13 310 9.5E-70 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS18045 581c2b03f72210009ae5c4ee1b945cee 255 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 30 215 2.7E-33 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAL12_RS18045 581c2b03f72210009ae5c4ee1b945cee 255 SUPERFAMILY SSF50486 25 230 2.12E-51 T 06-07-2017 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CAL12_RS18045 581c2b03f72210009ae5c4ee1b945cee 255 Gene3D G3DSA:3.10.300.10 26 227 2.4E-40 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAL12_RS18045 581c2b03f72210009ae5c4ee1b945cee 255 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 29 223 23.043 T 06-07-2017 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 36 52 2.0E-6 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 109 2.0E-6 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 151 165 2.0E-6 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 250 269 2.0E-6 T 06-07-2017 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 Pfam PF13416 Bacterial extracellular solute-binding protein 46 309 2.2E-29 T 06-07-2017 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 Gene3D G3DSA:3.40.190.10 30 151 6.8E-12 T 06-07-2017 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 Gene3D G3DSA:3.40.190.10 152 289 8.9E-37 T 06-07-2017 CAL12_RS23500 1b040dd0eca5c1190ab45d540ec20b94 350 SUPERFAMILY SSF53850 27 344 5.67E-57 T 06-07-2017 CAL12_RS03190 10f9bdaa5acad154dc36920a350185b1 283 SUPERFAMILY SSF161098 6 273 3.92E-51 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03190 10f9bdaa5acad154dc36920a350185b1 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 268 7.6E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03190 10f9bdaa5acad154dc36920a350185b1 283 Gene3D G3DSA:1.10.3720.10 7 275 3.3E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14000 3f7f77228cdf221f7673e3a5fa801d4f 682 Pfam PF01968 Hydantoinase/oxoprolinase 202 488 7.6E-99 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS14000 3f7f77228cdf221f7673e3a5fa801d4f 682 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 181 1.4E-54 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS14000 3f7f77228cdf221f7673e3a5fa801d4f 682 SUPERFAMILY SSF53067 1 78 3.42E-6 T 06-07-2017 CAL12_RS14000 3f7f77228cdf221f7673e3a5fa801d4f 682 SUPERFAMILY SSF53067 260 303 3.42E-6 T 06-07-2017 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.5E-7 T 06-07-2017 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 2.5E-7 T 06-07-2017 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 SUPERFAMILY SSF160996 202 349 3.27E-11 T 06-07-2017 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 SUPERFAMILY SSF51905 6 197 2.94E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 SUPERFAMILY SSF51905 348 406 2.94E-46 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 Pfam PF03486 HI0933-like protein 7 402 5.6E-107 T 06-07-2017 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 401 5.5E-84 T 06-07-2017 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 Gene3D G3DSA:3.50.50.60 350 405 7.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 Gene3D G3DSA:3.50.50.60 6 195 7.0E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02825 dfda66d5d181644200b617d8a44621f8 410 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 28 408 6.0E-169 T 06-07-2017 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.5E-37 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.5E-37 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.5E-37 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 Gene3D G3DSA:2.40.50.100 20 83 4.8E-29 T 06-07-2017 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 73 3.0E-14 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 4.2E-39 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 Pfam PF01016 Ribosomal L27 protein 2 82 3.0E-35 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 SUPERFAMILY SSF110324 2 81 1.22E-31 T 06-07-2017 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 06-07-2017 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS01780 75b02baa4faaf5f4484fa19586795582 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.097 T 06-07-2017 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 Gene3D G3DSA:3.20.20.70 6 301 7.2E-69 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 Pfam PF00701 Dihydrodipicolinate synthetase family 9 298 1.5E-40 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 PIRSF PIRSF001365 6 304 7.8E-52 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 SUPERFAMILY SSF51569 9 300 1.15E-64 T 06-07-2017 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 SMART SM01130 8 301 7.4E-68 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 4.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 4.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS23390 b395fa32b38641cde5bb0bd464a30fec 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 4.8E-6 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS16280 9c0ed5bf9d7891532a60df6b102f14f8 142 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 27 63 5.2E-6 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAL12_RS16280 9c0ed5bf9d7891532a60df6b102f14f8 142 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 64 126 2.2E-18 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAL12_RS16280 9c0ed5bf9d7891532a60df6b102f14f8 142 SUPERFAMILY SSF50249 12 133 5.65E-27 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS03705 864a271c16cd2f03f46cfc11b8ccab40 205 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 5 126 3.7E-28 T 06-07-2017 IPR012659 Conserved hypothetical protein CHP02444 CAL12_RS03705 864a271c16cd2f03f46cfc11b8ccab40 205 Pfam PF09523 Protein of unknown function (DUF2390) 5 122 5.6E-33 T 06-07-2017 IPR012659 Conserved hypothetical protein CHP02444 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 Pfam PF00361 Proton-conducting membrane transporter 140 424 7.1E-77 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 1.1E-48 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 1.1E-48 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 1.1E-48 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 1.1E-48 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 1.1E-48 T 06-07-2017 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 13 494 4.7E-184 T 06-07-2017 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19650 d43a0fb96e52c80378074feca3978420 499 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 70 132 6.9E-5 T 06-07-2017 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS10610 0a0faefbf6b8aac4bcf84d7c9f10a349 340 SUPERFAMILY SSF53850 111 302 1.93E-5 T 06-07-2017 CAL12_RS10610 0a0faefbf6b8aac4bcf84d7c9f10a349 340 PIRSF PIRSF017082 10 340 3.8E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10610 0a0faefbf6b8aac4bcf84d7c9f10a349 340 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 335 1.6E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 SUPERFAMILY SSF46785 7 85 8.16E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 Gene3D G3DSA:3.40.190.10 98 188 7.2E-15 T 06-07-2017 CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 Pfam PF03466 LysR substrate binding domain 97 295 8.5E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 Gene3D G3DSA:3.40.190.10 189 265 6.0E-18 T 06-07-2017 CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 Gene3D G3DSA:1.10.10.10 8 92 1.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 62 5.0E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS18800 18845021558bc42a13445355ff5abd68 304 SUPERFAMILY SSF53850 98 295 3.26E-31 T 06-07-2017 CAL12_RS01885 38c26b6589d05374c312eebdebe024d5 182 SUPERFAMILY SSF55729 11 173 1.74E-32 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS01885 38c26b6589d05374c312eebdebe024d5 182 Gene3D G3DSA:3.40.630.30 9 177 3.3E-39 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS01885 38c26b6589d05374c312eebdebe024d5 182 Pfam PF13420 Acetyltransferase (GNAT) domain 11 165 1.1E-19 T 06-07-2017 CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.1E-31 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 262 4.8E-63 T 06-07-2017 CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 SUPERFAMILY SSF51735 1 263 7.27E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06985 3c5c030a825ac2947447b62873fd7129 266 Gene3D G3DSA:3.40.50.720 1 263 4.5E-79 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14795 634abe64afcc869d205d630430a68960 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 305 3.1E-46 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14795 634abe64afcc869d205d630430a68960 322 PIRSF PIRSF017082 1 320 1.8E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14795 634abe64afcc869d205d630430a68960 322 SUPERFAMILY SSF53850 105 287 7.06E-7 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 Pfam PF00873 AcrB/AcrD/AcrF family 4 1042 7.8E-208 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82866 821 1044 1.05E-50 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82866 291 492 2.09E-40 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82693 40 135 6.8E-18 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 Gene3D G3DSA:1.10.3850.10 273 493 6.9E-51 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 Gene3D G3DSA:1.10.3850.10 828 1042 2.4E-54 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 Gene3D G3DSA:3.30.2090.10 184 267 6.5E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82693 269 325 8.89E-14 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82693 137 182 8.89E-14 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 Gene3D G3DSA:3.30.70.1430 40 140 2.5E-18 T 06-07-2017 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 SUPERFAMILY SSF82714 184 267 1.7E-13 T 06-07-2017 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS12575 23f4427276752136d877d4b872703d4f 1071 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 7.2E-39 T 06-07-2017 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Gene3D G3DSA:3.20.20.140 72 284 9.7E-108 T 06-07-2017 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Gene3D G3DSA:3.20.20.140 343 403 9.7E-108 T 06-07-2017 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Gene3D G3DSA:2.30.40.10 404 480 6.0E-10 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 SUPERFAMILY SSF51338 418 478 1.04E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 SUPERFAMILY SSF51338 4 57 1.04E-19 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Gene3D G3DSA:3.30.1490.130 287 342 1.7E-20 T 06-07-2017 IPR023100 D-aminoacylase, insert domain GO:0016811 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Gene3D G3DSA:2.30.40.10 4 71 6.8E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Pfam PF07969 Amidohydrolase family 349 461 1.8E-13 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 Pfam PF07969 Amidohydrolase family 47 221 1.1E-20 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS27715 61b55987ac388db9c83b26ee57ff9e52 484 SUPERFAMILY SSF51556 58 418 1.82E-86 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS26310 3f4c40e6fbe061dfe7e080910068105b 353 SUPERFAMILY SSF53187 35 346 3.21E-59 T 06-07-2017 CAL12_RS26310 3f4c40e6fbe061dfe7e080910068105b 353 PIRSF PIRSF039012 20 351 1.5E-67 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS26310 3f4c40e6fbe061dfe7e080910068105b 353 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 65 346 1.5E-52 T 06-07-2017 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 CAL12_RS26310 3f4c40e6fbe061dfe7e080910068105b 353 Gene3D G3DSA:3.40.630.10 29 252 1.1E-27 T 06-07-2017 CAL12_RS15030 e2669289e8d16d13d7c58eea3fbe6ac6 207 SUPERFAMILY SSF51182 7 195 3.53E-48 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS15030 e2669289e8d16d13d7c58eea3fbe6ac6 207 Gene3D G3DSA:2.60.120.10 44 184 1.5E-39 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS15030 e2669289e8d16d13d7c58eea3fbe6ac6 207 Pfam PF05995 Cysteine dioxygenase type I 77 159 1.4E-7 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAL12_RS25725 35cb917f5bdc6e03c35a2562bebd2e9e 298 Gene3D G3DSA:3.40.50.1820 29 274 1.6E-66 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25725 35cb917f5bdc6e03c35a2562bebd2e9e 298 SUPERFAMILY SSF53474 30 267 1.18E-15 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00585 fe1ad16420d65faef553157b6d37681e 116 Pfam PF08895 Domain of unknown function (DUF1840) 1 110 1.0E-29 T 06-07-2017 IPR014991 Protein of unknown function DUF1840 CAL12_RS07745 7ad7a5830e75d351da4fce754b1f8519 364 Gene3D G3DSA:3.40.190.10 147 235 6.2E-19 T 06-07-2017 CAL12_RS07745 7ad7a5830e75d351da4fce754b1f8519 364 Pfam PF09084 NMT1/THI5 like 72 285 6.9E-25 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS07745 7ad7a5830e75d351da4fce754b1f8519 364 SMART SM00062 64 285 0.0084 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS07745 7ad7a5830e75d351da4fce754b1f8519 364 SUPERFAMILY SSF53850 60 297 5.96E-35 T 06-07-2017 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 64 260 8.7E-88 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 81 101 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 189 209 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 210 231 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 234 259 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 101 120 3.8E-64 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 Pfam PF00813 FliP family 64 256 3.8E-78 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 189 204 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 120 132 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 250 260 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 160 172 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 60 69 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 132 146 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 182 194 5.6E-29 T 06-07-2017 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CAL12_RS11975 5b3301f4f7d569b0e597b6f6f9cd8822 262 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 237 249 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 155 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 234 250 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 263 282 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 427 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 118 136 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 453 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 357 375 3.1E-39 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 SUPERFAMILY SSF56235 8 542 1.65E-174 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS15925 8fe77c7a820c5b653c118b5de09c6f4a 542 Pfam PF01019 Gamma-glutamyltranspeptidase 36 537 8.6E-153 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14780 4713e53d1150dd6247eb7658a74b06d0 141 SUPERFAMILY SSF88723 6 130 5.33E-13 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS14780 4713e53d1150dd6247eb7658a74b06d0 141 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 6 119 1.1E-20 T 06-07-2017 IPR002850 PIN family, putative toxin-antitoxin system toxin component CAL12_RS14780 4713e53d1150dd6247eb7658a74b06d0 141 Pfam PF13470 PIN domain 6 114 3.0E-17 T 06-07-2017 IPR002716 PIN domain CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 228 5.9E-56 T 06-07-2017 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 SUPERFAMILY SSF75217 1 235 5.17E-91 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 PIRSF PIRSF000386 1 250 1.9E-89 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 Gene3D G3DSA:3.40.1280.10 1 164 1.0E-62 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 255 106.104 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 7.5E-86 T 06-07-2017 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAL12_RS09195 3499388efc0cbbeebd036752c9212d86 255 Gene3D G3DSA:1.10.1270.20 166 251 1.8E-28 T 06-07-2017 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 SUPERFAMILY SSF56176 4 218 9.82E-79 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 467 1.3E-49 T 06-07-2017 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 Gene3D G3DSA:3.30.43.10 3 96 1.6E-24 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 SUPERFAMILY SSF55103 191 467 4.25E-58 T 06-07-2017 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 Gene3D G3DSA:1.10.45.10 428 467 6.5E-12 T 06-07-2017 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 Pfam PF01565 FAD binding domain 42 177 5.2E-37 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS24110 b603c41483533c2fe30da077fddc04ac 468 Gene3D G3DSA:3.30.465.10 97 218 2.3E-38 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 TIGRFAM TIGR02822 adh_fam_2: zinc-binding alcohol dehydrogenase family protein 12 326 1.6E-98 T 06-07-2017 IPR014187 Alcohol dehydrogenase, zinc-binding type 2 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 SUPERFAMILY SSF50129 1 160 3.5E-49 T 06-07-2017 IPR011032 GroES-like CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 Gene3D G3DSA:3.40.50.720 167 296 3.1E-9 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 06-07-2017 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 Gene3D G3DSA:3.90.180.10 1 166 8.3E-56 T 06-07-2017 IPR011032 GroES-like CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 SMART SM00829 10 325 7.6E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 4.1E-31 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS14135 0bf51cfe0ed314dd0e533d745e0a5452 330 SUPERFAMILY SSF51735 138 295 7.07E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 SMART SM00062 34 275 4.0E-57 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 Gene3D G3DSA:3.40.190.10 31 118 4.6E-28 T 06-07-2017 CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 Gene3D G3DSA:3.40.190.10 236 277 4.6E-28 T 06-07-2017 CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 273 4.4E-49 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 SUPERFAMILY SSF53850 1 276 6.18E-61 T 06-07-2017 CAL12_RS05360 330b4728bbb4e3d4a85decbc977f60b8 309 Gene3D G3DSA:3.40.190.10 119 235 7.0E-21 T 06-07-2017 CAL12_RS20120 7cd1529af484a8abb4ba2d1cf8437030 356 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 78 351 3.0E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20120 7cd1529af484a8abb4ba2d1cf8437030 356 PIRSF PIRSF017082 21 353 2.2E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20120 7cd1529af484a8abb4ba2d1cf8437030 356 SUPERFAMILY SSF53850 150 316 6.15E-14 T 06-07-2017 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 31 188 4.3E-38 T 06-07-2017 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 Gene3D G3DSA:1.10.1040.10 282 485 3.5E-66 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 Gene3D G3DSA:3.40.50.720 29 281 2.6E-105 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 218 230 - T 06-07-2017 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 SUPERFAMILY SSF48179 283 485 1.22E-56 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 217 458 6.1E-74 T 06-07-2017 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 PRINTS PR00084 Mannitol dehydrogenase signature 32 42 9.2E-20 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 PRINTS PR00084 Mannitol dehydrogenase signature 218 231 9.2E-20 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 PRINTS PR00084 Mannitol dehydrogenase signature 179 192 9.2E-20 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 PRINTS PR00084 Mannitol dehydrogenase signature 248 263 9.2E-20 T 06-07-2017 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 CAL12_RS19100 2e0548f8da531d532c2a6f78bca7873b 488 SUPERFAMILY SSF51735 27 281 1.54E-94 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18480 6b0c02dbc759bbc4bdfd21b15651e62b 268 SUPERFAMILY SSF161098 60 244 3.14E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18480 6b0c02dbc759bbc4bdfd21b15651e62b 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 253 4.6E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18480 6b0c02dbc759bbc4bdfd21b15651e62b 268 Gene3D G3DSA:1.10.3720.10 56 254 2.6E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21110 f51bb05cc4637897baa759f84b00c4ad 325 SUPERFAMILY SSF53850 115 283 1.16E-7 T 06-07-2017 CAL12_RS21110 f51bb05cc4637897baa759f84b00c4ad 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 1.0E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21110 f51bb05cc4637897baa759f84b00c4ad 325 PIRSF PIRSF017082 2 324 1.4E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 Gene3D G3DSA:3.40.50.720 4 169 1.3E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 Pfam PF09130 Domain of unknown function (DUF1932) 190 259 6.4E-18 T 06-07-2017 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 SUPERFAMILY SSF48179 164 270 6.46E-22 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 142 5.1E-9 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 Gene3D G3DSA:1.10.1040.10 170 269 3.2E-12 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS10075 0709bdc3dffea8f54541a730ad419c8e 287 SUPERFAMILY SSF51735 4 161 1.16E-23 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04505 8dce158ba5c8cf130cd92d1f6d30c568 67 SUPERFAMILY SSF50249 10 66 2.15E-7 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS04505 8dce158ba5c8cf130cd92d1f6d30c568 67 Gene3D G3DSA:2.40.50.140 14 66 2.2E-8 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS04505 8dce158ba5c8cf130cd92d1f6d30c568 67 Pfam PF00313 'Cold-shock' DNA-binding domain 14 65 5.8E-5 T 06-07-2017 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CAL12_RS02945 c1f857214fb53585767b7e0af854a096 192 SUPERFAMILY SSF53335 5 184 1.35E-42 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02945 c1f857214fb53585767b7e0af854a096 192 Pfam PF03602 Conserved hypothetical protein 95 6 185 4.9E-45 T 06-07-2017 CAL12_RS02945 c1f857214fb53585767b7e0af854a096 192 PIRSF PIRSF004553 5 189 2.3E-39 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS02945 c1f857214fb53585767b7e0af854a096 192 Gene3D G3DSA:3.40.50.150 4 187 4.6E-54 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02945 c1f857214fb53585767b7e0af854a096 192 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 4 185 7.4E-37 T 06-07-2017 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 PIRSF PIRSF016262 1 206 5.8E-60 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 Hamap MF_00013 Octanoyltransferase [lipB]. 2 204 34.429 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 SUPERFAMILY SSF55681 7 203 7.54E-64 T 06-07-2017 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 23 183 5.2E-54 T 06-07-2017 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 Pfam PF03099 Biotin/lipoate A/B protein ligase family 55 161 4.2E-8 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 66 81 - T 06-07-2017 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 Gene3D G3DSA:3.90.1550.10 3 203 2.0E-68 T 06-07-2017 CAL12_RS26780 51d6059102146f957d822f144ee7f169 206 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 70 117 7.0E-12 T 06-07-2017 CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 PRINTS PR01576 Peptide deformylase signature 97 108 1.5E-29 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 PRINTS PR01576 Peptide deformylase signature 109 127 1.5E-29 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 PRINTS PR01576 Peptide deformylase signature 33 62 1.5E-29 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 PRINTS PR01576 Peptide deformylase signature 128 157 1.5E-29 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 PIRSF PIRSF004749 1 165 7.5E-49 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 Hamap MF_00163 Peptide deformylase [def]. 1 166 26.258 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 Pfam PF01327 Polypeptide deformylase 3 159 6.2E-49 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 3 159 2.9E-35 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 Gene3D G3DSA:3.90.45.10 1 160 6.9E-55 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS06320 27fc72231ca129998285fc6b42982a99 177 SUPERFAMILY SSF56420 1 164 2.36E-58 T 06-07-2017 IPR023635 Peptide deformylase CAL12_RS16655 7ee71eadaeb88b4c28142288ca73f521 135 Pfam PF09391 Protein of unknown function (DUF2000) 4 135 4.2E-40 T 06-07-2017 IPR018988 Protein of unknown function DUF2000 CAL12_RS16655 7ee71eadaeb88b4c28142288ca73f521 135 SUPERFAMILY SSF102462 2 135 1.26E-42 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAL12_RS16655 7ee71eadaeb88b4c28142288ca73f521 135 Gene3D G3DSA:3.40.1490.10 2 135 1.0E-51 T 06-07-2017 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CAL12_RS03590 15c1e1c53a22bb28375ce8e2cb387996 245 SUPERFAMILY SSF53335 40 222 6.83E-20 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS03590 15c1e1c53a22bb28375ce8e2cb387996 245 PIRSF PIRSF031679 1 245 1.0E-67 T 06-07-2017 IPR016980 S-adenosyl-L-methionine dependent methyltransferase, Alr7345, predicted CAL12_RS03590 15c1e1c53a22bb28375ce8e2cb387996 245 Gene3D G3DSA:3.40.50.150 32 219 7.2E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS16710 02f8bae2b5a71fb8c116d2642410b826 353 SUPERFAMILY SSF51430 1 319 3.4E-103 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS16710 02f8bae2b5a71fb8c116d2642410b826 353 Gene3D G3DSA:3.20.20.100 1 320 2.4E-105 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS16710 02f8bae2b5a71fb8c116d2642410b826 353 Pfam PF00248 Aldo/keto reductase family 15 320 5.4E-75 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS04785 bcbec0a7416b687d8cf69b5baf149e99 177 SUPERFAMILY SSF52833 33 171 6.96E-39 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS04785 bcbec0a7416b687d8cf69b5baf149e99 177 Gene3D G3DSA:3.40.30.10 31 173 1.6E-52 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS04785 bcbec0a7416b687d8cf69b5baf149e99 177 Pfam PF08534 Redoxin 32 162 6.8E-15 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAL12_RS13185 8fb64d084ce0f518dbbe60eabb9af854 335 SUPERFAMILY SSF53474 12 320 9.55E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13185 8fb64d084ce0f518dbbe60eabb9af854 335 Gene3D G3DSA:3.40.50.1820 7 324 4.7E-103 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10775 6168725763296e739c073c40e56998bd 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 254 9.0E-49 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS10775 6168725763296e739c073c40e56998bd 266 SMART SM00062 37 256 8.3E-43 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS10775 6168725763296e739c073c40e56998bd 266 SUPERFAMILY SSF53850 11 256 7.58E-56 T 06-07-2017 CAL12_RS10775 6168725763296e739c073c40e56998bd 266 Gene3D G3DSA:3.40.190.10 211 253 5.9E-33 T 06-07-2017 CAL12_RS10775 6168725763296e739c073c40e56998bd 266 Gene3D G3DSA:3.40.190.10 32 112 5.9E-33 T 06-07-2017 CAL12_RS10775 6168725763296e739c073c40e56998bd 266 Gene3D G3DSA:3.40.190.10 113 207 4.1E-14 T 06-07-2017 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Pfam PF13581 Histidine kinase-like ATPase domain 19 132 1.2E-9 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SMART SM00448 439 552 1.1E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Pfam PF00072 Response regulator receiver domain 441 552 2.5E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SUPERFAMILY SSF55874 32 133 1.3E-12 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SMART SM00387 306 419 1.5E-30 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SMART SM00387 35 137 1.6E-5 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Pfam PF00512 His Kinase A (phospho-acceptor) domain 194 258 5.9E-16 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Gene3D G3DSA:3.30.565.10 28 135 1.0E-11 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 307 416 1.6E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 357 2.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 2.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 371 2.1E-14 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Gene3D G3DSA:1.10.287.130 185 247 6.9E-15 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SUPERFAMILY SSF47384 179 261 4.32E-18 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SUPERFAMILY SSF52172 437 556 1.11E-31 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Gene3D G3DSA:3.40.50.2300 435 557 3.2E-31 T 06-07-2017 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SMART SM00388 193 260 7.5E-19 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 SUPERFAMILY SSF55874 249 419 2.49E-42 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26655 2d7cc8b1254c899ec461408b85611c66 559 Gene3D G3DSA:3.30.565.10 248 418 1.0E-41 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS26065 3a5fabf7f4a84663ba42fefa9fdecc42 844 Hamap MF_01072 Glucans biosynthesis glucosyltransferase H [mdoH]. 82 740 49.737 T 06-07-2017 IPR023725 Glucan biosynthesis glucosyltransferase H GO:0016758 CAL12_RS26065 3a5fabf7f4a84663ba42fefa9fdecc42 844 Gene3D G3DSA:3.90.550.10 241 384 3.5E-5 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26065 3a5fabf7f4a84663ba42fefa9fdecc42 844 Pfam PF00535 Glycosyl transferase family 2 241 421 1.1E-21 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS26065 3a5fabf7f4a84663ba42fefa9fdecc42 844 SUPERFAMILY SSF53448 239 528 1.24E-26 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS16255 4d5a78cc532bd909c308a8ec837d3b12 231 SUPERFAMILY SSF52540 2 225 2.79E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16255 4d5a78cc532bd909c308a8ec837d3b12 231 Pfam PF00005 ABC transporter 21 166 6.9E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS16255 4d5a78cc532bd909c308a8ec837d3b12 231 Gene3D G3DSA:3.40.50.300 2 226 4.2E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS16255 4d5a78cc532bd909c308a8ec837d3b12 231 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS16255 4d5a78cc532bd909c308a8ec837d3b12 231 SMART SM00382 30 215 2.3E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS04110 9bf183c1f13d4fc51b9fa5a42b334d77 124 Gene3D G3DSA:3.10.450.50 1 124 4.7E-59 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS04110 9bf183c1f13d4fc51b9fa5a42b334d77 124 Pfam PF11533 Protein of unknown function (DUF3225) 1 123 6.1E-62 T 06-07-2017 IPR024507 Protein of unknown function DUF3225 CAL12_RS04110 9bf183c1f13d4fc51b9fa5a42b334d77 124 SUPERFAMILY SSF54427 1 123 1.15E-40 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 SUPERFAMILY SSF55021 79 162 1.25E-25 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 Gene3D G3DSA:3.30.70.260 1 78 9.8E-38 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 Pfam PF13710 ACT domain 12 73 8.3E-16 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 1.4E-64 T 06-07-2017 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 Gene3D G3DSA:3.30.70.1150 83 162 8.6E-30 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 SUPERFAMILY SSF55021 1 76 6.87E-23 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 4.0E-35 T 06-07-2017 CAL12_RS20940 2aa37cbd3cfee61966dabfac7de97e8e 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 3.4E-27 T 06-07-2017 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CAL12_RS22590 a5b065f213e3551e0d985093b538430f 507 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 440 2.6E-133 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAL12_RS01635 17effb3f44fcf61893ef87b2725d4e16 276 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 10 267 3.6E-106 T 06-07-2017 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 CAL12_RS01635 17effb3f44fcf61893ef87b2725d4e16 276 Gene3D G3DSA:1.10.3720.10 12 260 1.0E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01635 17effb3f44fcf61893ef87b2725d4e16 276 SUPERFAMILY SSF161098 7 258 8.5E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01635 17effb3f44fcf61893ef87b2725d4e16 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 264 1.6E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01635 17effb3f44fcf61893ef87b2725d4e16 276 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 8 265 3.0E-93 T 06-07-2017 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 CAL12_RS01925 23d127f52cdc4a4c4b82196aa4f5a255 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 296 7.5E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS01925 23d127f52cdc4a4c4b82196aa4f5a255 401 Gene3D G3DSA:2.40.50.100 179 208 1.8E-22 T 06-07-2017 CAL12_RS01925 23d127f52cdc4a4c4b82196aa4f5a255 401 Gene3D G3DSA:2.40.50.100 71 104 1.8E-22 T 06-07-2017 CAL12_RS01925 23d127f52cdc4a4c4b82196aa4f5a255 401 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 377 1.5E-87 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS01925 23d127f52cdc4a4c4b82196aa4f5a255 401 SUPERFAMILY SSF111369 60 301 3.14E-67 T 06-07-2017 CAL12_RS23555 06c6b1da17ed86e727b1e2e6bc0c4af7 108 SUPERFAMILY SSF46785 7 106 7.92E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23555 06c6b1da17ed86e727b1e2e6bc0c4af7 108 Gene3D G3DSA:1.10.10.10 1 105 6.1E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23555 06c6b1da17ed86e727b1e2e6bc0c4af7 108 Pfam PF01638 HxlR-like helix-turn-helix 19 104 6.8E-22 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS06155 d265c4c77d4a2180a6e173504be21346 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 320 1.2E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06155 d265c4c77d4a2180a6e173504be21346 323 PIRSF PIRSF017082 1 323 2.3E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06155 d265c4c77d4a2180a6e173504be21346 323 SUPERFAMILY SSF53850 112 285 1.05E-8 T 06-07-2017 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 Gene3D G3DSA:3.40.810.20 10 220 3.6E-72 T 06-07-2017 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 SMART SM00882 11 209 2.1E-58 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 SUPERFAMILY SSF100950 10 219 3.43E-58 T 06-07-2017 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 Pfam PF01144 Coenzyme A transferase 13 206 4.2E-30 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 9 215 4.3E-78 T 06-07-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 CAL12_RS24430 f9b70330d4a6833d97a23779ab4dffbd 223 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 49 57 - T 06-07-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 CAL12_RS14205 847ef89f24c15c0d4235099a2b1cedc4 372 Pfam PF03929 PepSY-associated TM region 11 365 3.7E-47 T 06-07-2017 IPR005625 PepSY-associated TM protein CAL12_RS14315 4db88295859870244dd9ce41ae9b7636 378 Gene3D G3DSA:3.40.50.720 21 169 1.5E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14315 4db88295859870244dd9ce41ae9b7636 378 SUPERFAMILY SSF51735 21 201 9.57E-38 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14315 4db88295859870244dd9ce41ae9b7636 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 27 141 1.5E-16 T 06-07-2017 IPR000683 Oxidoreductase, N-terminal GO:0016491 CAL12_RS14315 4db88295859870244dd9ce41ae9b7636 378 Gene3D G3DSA:3.30.360.10 170 361 2.0E-17 T 06-07-2017 CAL12_RS14315 4db88295859870244dd9ce41ae9b7636 378 SUPERFAMILY SSF55347 159 319 1.9E-17 T 06-07-2017 CAL12_RS10765 a897c6d62272a6fd1468d25982430a23 217 Gene3D G3DSA:1.10.3720.10 13 213 1.2E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10765 a897c6d62272a6fd1468d25982430a23 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 2.4E-26 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS10765 a897c6d62272a6fd1468d25982430a23 217 SUPERFAMILY SSF161098 13 204 4.97E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10765 a897c6d62272a6fd1468d25982430a23 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 206 3.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05945 b6ed5fab42286fb8d3833c438ba1c3c4 283 Gene3D G3DSA:3.90.850.10 65 282 1.6E-77 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS05945 b6ed5fab42286fb8d3833c438ba1c3c4 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 279 8.0E-65 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS05945 b6ed5fab42286fb8d3833c438ba1c3c4 283 SUPERFAMILY SSF56529 63 281 6.54E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 Pfam PF00202 Aminotransferase class-III 32 442 1.4E-110 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 PIRSF PIRSF000521 35 448 1.7E-31 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 Gene3D G3DSA:3.90.1150.10 13 71 2.2E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 Gene3D G3DSA:3.90.1150.10 349 445 2.2E-47 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 SUPERFAMILY SSF53383 18 444 1.58E-118 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 21 443 7.6E-159 T 06-07-2017 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CAL12_RS04800 8757d9e8657d146b95beedc8ecbcd7fe 452 Gene3D G3DSA:3.40.640.10 72 346 2.6E-88 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS19830 57d2fe1e32a99d8b93fd6e95929f79cf 487 Gene3D G3DSA:3.30.1330.120 301 440 6.0E-18 T 06-07-2017 CAL12_RS19830 57d2fe1e32a99d8b93fd6e95929f79cf 487 SUPERFAMILY SSF103378 34 483 1.03E-106 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS19830 57d2fe1e32a99d8b93fd6e95929f79cf 487 Pfam PF03972 MmgE/PrpD family 35 476 8.3E-116 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS10910 6964c0189ee95319c3385be5c4658153 283 SUPERFAMILY SSF56784 2 231 8.92E-13 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS10910 6964c0189ee95319c3385be5c4658153 283 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 211 2.6E-9 T 06-07-2017 CAL12_RS10910 6964c0189ee95319c3385be5c4658153 283 Gene3D G3DSA:3.40.50.1000 88 224 1.3E-5 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS10910 6964c0189ee95319c3385be5c4658153 283 Gene3D G3DSA:3.40.50.1000 6 20 1.3E-5 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21875 f9d351e7739d7c1a26ff4d4c81a79f67 172 SUPERFAMILY SSF52016 7 165 3.14E-35 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS21875 f9d351e7739d7c1a26ff4d4c81a79f67 172 Pfam PF00694 Aconitase C-terminal domain 60 112 1.3E-12 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS21875 f9d351e7739d7c1a26ff4d4c81a79f67 172 Gene3D G3DSA:3.20.19.10 7 164 8.7E-20 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS21875 f9d351e7739d7c1a26ff4d4c81a79f67 172 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 11 164 5.8E-44 T 06-07-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CAL12_RS11035 676828ccc39595903e7091b54d92d668 326 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 21 310 1.8E-50 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS11035 676828ccc39595903e7091b54d92d668 326 SUPERFAMILY SSF51197 25 311 5.95E-87 T 06-07-2017 CAL12_RS11035 676828ccc39595903e7091b54d92d668 326 Gene3D G3DSA:3.60.130.10 14 313 1.2E-66 T 06-07-2017 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 SUPERFAMILY SSF46785 9 138 3.08E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 7.6E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 Pfam PF01047 MarR family 34 87 2.4E-13 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 SMART SM00347 24 124 6.4E-19 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09365 343d72965bca75100c192b31bcdbe4fd 147 Gene3D G3DSA:1.10.10.10 12 139 1.6E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20925 12e020c47e1a23d6ae9b09e9d2f37c3c 258 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAL12_RS20925 12e020c47e1a23d6ae9b09e9d2f37c3c 258 Pfam PF01066 CDP-alcohol phosphatidyltransferase 19 82 1.9E-13 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAL12_RS20925 12e020c47e1a23d6ae9b09e9d2f37c3c 258 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 160 9.2E-33 T 06-07-2017 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CAL12_RS05105 a362a05734771c4abda5de9ebba40638 293 SUPERFAMILY SSF46785 16 100 5.92E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05105 a362a05734771c4abda5de9ebba40638 293 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 20 86 6.6E-20 T 06-07-2017 IPR002831 Transcription regulator TrmB, N-terminal CAL12_RS05105 a362a05734771c4abda5de9ebba40638 293 Gene3D G3DSA:1.10.10.10 15 109 1.3E-8 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05105 a362a05734771c4abda5de9ebba40638 293 Pfam PF11495 Archaeal transcriptional regulator TrmB 119 212 3.1E-6 T 06-07-2017 IPR021586 Transcription regulator TrmB, C-terminal CAL12_RS03455 c678da2e550d84992704614eede77584 114 Gene3D G3DSA:3.10.20.30 25 94 8.6E-6 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS03455 c678da2e550d84992704614eede77584 114 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 22 102 2.3E-29 T 06-07-2017 CAL12_RS03455 c678da2e550d84992704614eede77584 114 SUPERFAMILY SSF54292 24 104 8.91E-20 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23820 270ab05ca8722b839f771e419aab2008 350 PIRSF PIRSF017082 19 350 3.9E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23820 270ab05ca8722b839f771e419aab2008 350 SUPERFAMILY SSF53850 135 312 7.33E-9 T 06-07-2017 CAL12_RS23820 270ab05ca8722b839f771e419aab2008 350 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 73 346 7.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 06-07-2017 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 SUPERFAMILY SSF81333 4 77 4.71E-18 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 7 75 13.78 T 06-07-2017 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 Gene3D G3DSA:1.20.20.10 3 77 1.2E-33 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 10 29 8.9E-5 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 31 46 8.9E-5 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 48 73 8.9E-5 T 06-07-2017 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 Pfam PF00137 ATP synthase subunit C 9 71 2.0E-10 T 06-07-2017 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CAL12_RS25820 cf4006087a82c17e662058977fa39787 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 7.9E-22 T 06-07-2017 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 SMART SM00116 314 361 0.29 T 06-07-2017 IPR000644 CBS domain CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 SMART SM00116 244 292 1.4E-5 T 06-07-2017 IPR000644 CBS domain CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 Pfam PF04982 HPP family 54 173 4.5E-34 T 06-07-2017 IPR007065 HPP CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 Gene3D G3DSA:3.10.580.10 236 361 2.0E-20 T 06-07-2017 CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 Pfam PF00571 CBS domain 238 283 2.2E-8 T 06-07-2017 IPR000644 CBS domain CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 Pfam PF00571 CBS domain 308 360 6.3E-6 T 06-07-2017 IPR000644 CBS domain CAL12_RS01305 85278f4fdb3cc0844b28f1bc5342b11a 385 SUPERFAMILY SSF54631 226 362 4.21E-21 T 06-07-2017 CAL12_RS10905 cf1b5ff53fea372093f18f657f6b84db 391 SUPERFAMILY SSF53474 103 309 2.75E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10905 cf1b5ff53fea372093f18f657f6b84db 391 SUPERFAMILY SSF53474 338 362 2.75E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10905 cf1b5ff53fea372093f18f657f6b84db 391 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 110 316 6.2E-39 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAL12_RS10905 cf1b5ff53fea372093f18f657f6b84db 391 Gene3D G3DSA:3.40.50.1820 99 380 2.1E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10905 cf1b5ff53fea372093f18f657f6b84db 391 Pfam PF10503 Esterase PHB depolymerase 108 317 4.3E-66 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Gene3D G3DSA:2.40.40.20 606 758 3.0E-47 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Gene3D G3DSA:3.90.55.10 461 563 2.2E-33 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Pfam PF01568 Molydopterin dinucleotide binding domain 631 749 5.8E-25 T 06-07-2017 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Gene3D G3DSA:3.40.50.740 357 460 3.7E-37 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Gene3D G3DSA:3.40.50.740 51 150 3.7E-37 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Gene3D G3DSA:3.40.228.10 151 356 7.5E-46 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 SUPERFAMILY SSF53706 16 618 6.54E-156 T 06-07-2017 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 Pfam PF00384 Molybdopterin oxidoreductase 57 514 4.6E-57 T 06-07-2017 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS07510 333b08ec9c170ff3dbdaa52de15860eb 766 SUPERFAMILY SSF50692 624 757 1.63E-36 T 06-07-2017 IPR009010 Aspartate decarboxylase-like domain CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 SUPERFAMILY SSF47741 92 161 2.75E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 47 55 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 67 1.5E-7 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 Pfam PF01799 [2Fe-2S] binding domain 81 153 1.4E-23 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 Gene3D G3DSA:3.10.20.30 9 82 8.4E-25 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 SUPERFAMILY SSF54292 11 86 9.7E-21 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS21405 1ec0595c8ae233ed7b0db8a84aed165a 169 Gene3D G3DSA:1.10.150.120 83 161 1.7E-26 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21565 ee0bbb89f2cd041f73df5e6a850d7396 738 ProSitePatterns PS00018 EF-hand calcium-binding domain. 505 517 - T 06-07-2017 IPR018247 EF-Hand 1, calcium-binding site CAL12_RS21565 ee0bbb89f2cd041f73df5e6a850d7396 738 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 43 724 1.3E-222 T 06-07-2017 IPR019899 Sodium/solute symporter, VC2705 subfamily CAL12_RS21565 ee0bbb89f2cd041f73df5e6a850d7396 738 Pfam PF00474 Sodium:solute symporter family 416 649 2.2E-19 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS21565 ee0bbb89f2cd041f73df5e6a850d7396 738 Pfam PF00474 Sodium:solute symporter family 68 237 5.0E-30 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS00705 a3637f84230a59d3c9c124f938552c0b 524 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 479 3.9E-99 T 06-07-2017 IPR010352 Protein of unknown function DUF945 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 Pfam PF03170 Bacterial cellulose synthase subunit 69 676 1.7E-224 T 06-07-2017 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 476 495 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 397 418 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 561 581 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 524 543 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 187 208 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 97 118 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS00285 d0d9423910d4a041a478c62f4103b17d 773 PRINTS PR01440 Cellulose synthase subunit B signature 229 252 4.5E-39 T 06-07-2017 IPR003920 Cellulose synthase, subunit B GO:0006011|GO:0016020 CAL12_RS19980 2da4be7486e5323ade535ffec3ee26f8 362 Gene3D G3DSA:3.40.50.150 77 354 1.5E-80 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19980 2da4be7486e5323ade535ffec3ee26f8 362 SUPERFAMILY SSF53335 83 352 1.53E-55 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19980 2da4be7486e5323ade535ffec3ee26f8 362 Pfam PF02353 Mycolic acid cyclopropane synthetase 80 341 5.2E-37 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 Pfam PF07687 Peptidase dimerisation domain 222 320 5.6E-17 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 Gene3D G3DSA:3.30.70.360 226 329 6.8E-24 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 SUPERFAMILY SSF55031 225 336 5.63E-20 T 06-07-2017 IPR011650 Peptidase M20, dimerisation domain CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 Gene3D G3DSA:3.40.630.10 33 225 2.8E-48 T 06-07-2017 CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 Gene3D G3DSA:3.40.630.10 334 425 2.8E-48 T 06-07-2017 CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 118 127 - T 06-07-2017 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 Pfam PF01546 Peptidase family M20/M25/M40 119 421 2.6E-24 T 06-07-2017 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 PIRSF PIRSF037238 33 425 2.9E-101 T 06-07-2017 IPR017150 Peptidase M20, glutamate carboxypeptidase CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 SUPERFAMILY SSF53187 33 233 3.43E-49 T 06-07-2017 CAL12_RS12805 f8f1ea50b3c9330f9fafcc395ff5da1d 433 SUPERFAMILY SSF53187 345 425 3.43E-49 T 06-07-2017 CAL12_RS26670 9ddfb11e6ccb95a9fbf70ab24f2c2286 124 Pfam PF01740 STAS domain 14 95 3.2E-5 T 06-07-2017 IPR002645 STAS domain CAL12_RS26670 9ddfb11e6ccb95a9fbf70ab24f2c2286 124 SUPERFAMILY SSF52091 3 114 7.26E-17 T 06-07-2017 IPR002645 STAS domain CAL12_RS26670 9ddfb11e6ccb95a9fbf70ab24f2c2286 124 Gene3D G3DSA:3.30.750.24 8 95 5.5E-10 T 06-07-2017 IPR002645 STAS domain CAL12_RS19525 d9c08f1feb0f9a841af617721dbcbe9e 183 PIRSF PIRSF016661 1 181 1.1E-43 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CAL12_RS19525 d9c08f1feb0f9a841af617721dbcbe9e 183 Pfam PF02632 BioY family 31 178 4.1E-37 T 06-07-2017 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CAL12_RS06510 fdbcb05191991e6217fa0fced1f4f210 299 Gene3D G3DSA:2.60.120.330 124 222 2.4E-16 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAL12_RS06510 fdbcb05191991e6217fa0fced1f4f210 299 SUPERFAMILY SSF51197 98 222 8.79E-18 T 06-07-2017 CAL12_RS06510 fdbcb05191991e6217fa0fced1f4f210 299 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 69 222 1.9E-46 T 06-07-2017 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CAL12_RS07735 64343e7cc08d0bec401bdf6a5ee22d6f 215 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 186 9.3E-46 T 06-07-2017 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CAL12_RS07735 64343e7cc08d0bec401bdf6a5ee22d6f 215 Pfam PF00694 Aconitase C-terminal domain 8 117 5.5E-21 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS07735 64343e7cc08d0bec401bdf6a5ee22d6f 215 SUPERFAMILY SSF52016 6 193 6.47E-41 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS07735 64343e7cc08d0bec401bdf6a5ee22d6f 215 Gene3D G3DSA:3.20.19.10 9 195 1.9E-32 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 Gene3D G3DSA:2.40.50.140 7 80 6.8E-6 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 Pfam PF11967 Recombination protein O N terminal 10 81 5.8E-19 T 06-07-2017 IPR022572 DNA replication/recombination mediator RecO, N-terminal CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 Pfam PF02565 Recombination protein O C terminal 91 151 3.4E-15 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 SUPERFAMILY SSF57863 92 149 2.33E-7 T 06-07-2017 CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 TIGRFAM TIGR00613 reco: DNA repair protein RecO 11 151 3.7E-17 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 SUPERFAMILY SSF50249 9 82 1.3E-11 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS08425 e204108961942abab5a29d3415e3c08e 204 Hamap MF_00201 DNA repair protein RecO [recO]. 7 204 14.984 T 06-07-2017 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 SUPERFAMILY SSF51735 6 254 2.13E-65 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 2.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 PIRSF PIRSF000094 1 259 8.9E-113 T 06-07-2017 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 6.0E-87 T 06-07-2017 CAL12_RS24255 ce4319ca777b3741b774b3a66f1a61b4 260 Gene3D G3DSA:3.40.50.720 6 202 1.4E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00235 7bfa8b7993949c9f2d6fd64e94032f30 216 Gene3D G3DSA:1.20.950.20 17 210 5.1E-46 T 06-07-2017 CAL12_RS00235 7bfa8b7993949c9f2d6fd64e94032f30 216 Pfam PF01292 Prokaryotic cytochrome b561 20 208 8.4E-23 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS00235 7bfa8b7993949c9f2d6fd64e94032f30 216 SUPERFAMILY SSF81342 16 210 1.02E-33 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS04880 32f7b10794beb4c416056f3ec1edf4c7 249 SUPERFAMILY SSF48317 30 238 8.76E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS04880 32f7b10794beb4c416056f3ec1edf4c7 249 Gene3D G3DSA:1.20.144.10 43 222 7.1E-30 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS04880 32f7b10794beb4c416056f3ec1edf4c7 249 Pfam PF01569 PAP2 superfamily 114 227 9.3E-19 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS04880 32f7b10794beb4c416056f3ec1edf4c7 249 SMART SM00014 113 224 6.5E-5 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 Gene3D G3DSA:1.10.275.10 7 122 8.1E-45 T 06-07-2017 IPR024083 Fumarase/histidase, N-terminal CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 SUPERFAMILY SSF48557 14 454 5.34E-102 T 06-07-2017 IPR008948 L-Aspartase-like GO:0003824 CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 454 7.3E-125 T 06-07-2017 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 Gene3D G3DSA:1.20.200.10 123 392 3.7E-87 T 06-07-2017 CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 Pfam PF00206 Lyase 18 315 1.4E-58 T 06-07-2017 IPR022761 Fumarate lyase, N-terminal CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 2.8E-16 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 PRINTS PR00149 Fumarate lyase superfamily signature 254 281 2.8E-16 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 2.8E-16 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 2.8E-16 T 06-07-2017 IPR000362 Fumarate lyase family CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 06-07-2017 IPR020557 Fumarate lyase, conserved site GO:0003824 CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 3.7E-49 T 06-07-2017 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 CAL12_RS17725 1cbdff2dfbb549e453878b5539fade4f 458 Gene3D G3DSA:1.10.40.30 393 448 8.3E-31 T 06-07-2017 CAL12_RS18825 de3295eb02a7815acec3d7bcf5b0140e 338 SUPERFAMILY SSF53850 129 296 1.03E-10 T 06-07-2017 CAL12_RS18825 de3295eb02a7815acec3d7bcf5b0140e 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 330 9.0E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18825 de3295eb02a7815acec3d7bcf5b0140e 338 PIRSF PIRSF017082 11 336 3.9E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14575 de91c2dfe3ada83e667d4d7f25be647e 320 Pfam PF04909 Amidohydrolase 48 315 3.4E-34 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS14575 de91c2dfe3ada83e667d4d7f25be647e 320 SUPERFAMILY SSF51556 42 315 3.71E-63 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS14575 de91c2dfe3ada83e667d4d7f25be647e 320 Gene3D G3DSA:3.20.20.140 26 317 2.5E-86 T 06-07-2017 CAL12_RS00460 2cccb1bf9a2a0e72140488fc71f5d7fc 916 Pfam PF14345 GDYXXLXY protein 760 908 4.5E-37 T 06-07-2017 IPR025833 GDYXXLXY protein CAL12_RS00460 2cccb1bf9a2a0e72140488fc71f5d7fc 916 Pfam PF09925 Predicted membrane protein (DUF2157) 19 136 2.9E-20 T 06-07-2017 IPR018677 Domain of unknown function DUF2157 CAL12_RS00460 2cccb1bf9a2a0e72140488fc71f5d7fc 916 Pfam PF14351 Domain of unknown function (DUF4401) 395 725 3.9E-58 T 06-07-2017 IPR025513 Domain of unknown function DUF4401 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 2.1E-19 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 344 2.1E-19 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 37 56 2.1E-19 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 200 218 2.1E-19 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 35 365 4.5E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 Gene3D G3DSA:3.50.50.60 35 145 5.3E-16 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 Gene3D G3DSA:3.50.50.60 146 372 4.4E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 SUPERFAMILY SSF51905 21 370 5.34E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 58 1.8E-7 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 344 1.8E-7 T 06-07-2017 CAL12_RS21250 94fbdf955b896acf5053d712324aa1f6 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 200 225 1.8E-7 T 06-07-2017 CAL12_RS24210 cac6474c39b649b2b552b0606d237105 346 Pfam PF00144 Beta-lactamase 71 326 1.2E-10 T 06-07-2017 IPR001466 Beta-lactamase-related CAL12_RS24210 cac6474c39b649b2b552b0606d237105 346 Gene3D G3DSA:3.40.710.10 73 326 3.8E-27 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS24210 cac6474c39b649b2b552b0606d237105 346 SUPERFAMILY SSF56601 48 335 4.93E-50 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS06165 575ca7199718de78c8d215e34a14616c 262 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 253 8.0E-119 T 06-07-2017 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 CAL12_RS06165 575ca7199718de78c8d215e34a14616c 262 SUPERFAMILY SSF51658 1 253 3.67E-86 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06165 575ca7199718de78c8d215e34a14616c 262 Gene3D G3DSA:3.20.20.150 1 253 2.6E-92 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06165 575ca7199718de78c8d215e34a14616c 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 9.2E-35 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06165 575ca7199718de78c8d215e34a14616c 262 PIRSF PIRSF006241 1 260 9.0E-95 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CAL12_RS11645 c00b6cd71650d534eee40566de364d51 449 Gene3D G3DSA:3.30.1330.120 265 400 3.4E-20 T 06-07-2017 CAL12_RS11645 c00b6cd71650d534eee40566de364d51 449 Pfam PF03972 MmgE/PrpD family 7 431 1.8E-113 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS11645 c00b6cd71650d534eee40566de364d51 449 SUPERFAMILY SSF103378 2 445 2.88E-107 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27875 93f0f712dfcaf5265f2e017dde468d68 152 Pfam PF13463 Winged helix DNA-binding domain 40 103 1.0E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS27875 93f0f712dfcaf5265f2e017dde468d68 152 SUPERFAMILY SSF46785 11 140 8.4E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27875 93f0f712dfcaf5265f2e017dde468d68 152 Gene3D G3DSA:1.10.10.10 4 140 1.2E-30 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27875 93f0f712dfcaf5265f2e017dde468d68 152 SMART SM00347 30 130 9.7E-12 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS13610 1778fa5faa1b3e403dcdc075a9d2c76f 172 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 161 32.917 T 06-07-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CAL12_RS13610 1778fa5faa1b3e403dcdc075a9d2c76f 172 SUPERFAMILY SSF52016 4 159 1.53E-38 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS13610 1778fa5faa1b3e403dcdc075a9d2c76f 172 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 157 2.1E-52 T 06-07-2017 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0008152|GO:0016836 KEGG: 00290+4.2.1.33 CAL12_RS13610 1778fa5faa1b3e403dcdc075a9d2c76f 172 Pfam PF00694 Aconitase C-terminal domain 49 100 2.1E-14 T 06-07-2017 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CAL12_RS13610 1778fa5faa1b3e403dcdc075a9d2c76f 172 Gene3D G3DSA:3.20.19.10 7 131 1.1E-23 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS11395 824543899cbc12b7efd9d60026d436ce 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 133 8.4E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS13155 f5d719c20f685c93701f2b4750362772 229 Pfam PF11445 Protein of unknown function (DUF2894) 8 203 7.9E-60 T 06-07-2017 IPR021549 Protein of unknown function DUF2894 CAL12_RS26805 12399a20bb9496599f6b88941a8dd52f 493 Gene3D G3DSA:3.40.640.10 227 353 8.1E-24 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS26805 12399a20bb9496599f6b88941a8dd52f 493 SUPERFAMILY SSF53383 52 469 1.68E-58 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS26805 12399a20bb9496599f6b88941a8dd52f 493 Pfam PF00202 Aminotransferase class-III 62 143 1.3E-5 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS26805 12399a20bb9496599f6b88941a8dd52f 493 Pfam PF00202 Aminotransferase class-III 248 466 2.3E-38 T 06-07-2017 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CAL12_RS26805 12399a20bb9496599f6b88941a8dd52f 493 Gene3D G3DSA:3.90.1150.10 354 469 3.0E-29 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS10965 e4f820c79560f7bb1000abcdbb19c6ad 139 Gene3D G3DSA:2.60.40.10 70 127 3.2E-7 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS10965 e4f820c79560f7bb1000abcdbb19c6ad 139 SUPERFAMILY SSF49452 70 138 7.26E-7 T 06-07-2017 IPR013784 Carbohydrate-binding-like fold GO:0030246 CAL12_RS15220 afe0ac07c8889439ebaedc0e59e9b5fa 197 Gene3D G3DSA:3.40.50.1820 6 173 4.7E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS15220 afe0ac07c8889439ebaedc0e59e9b5fa 197 Pfam PF06821 Serine hydrolase 6 172 1.9E-61 T 06-07-2017 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CAL12_RS15220 afe0ac07c8889439ebaedc0e59e9b5fa 197 SUPERFAMILY SSF53474 6 170 1.1E-33 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24780 fe782762e55e5a2c26efc0c9a589f500 454 SUPERFAMILY SSF111283 17 454 2.22E-123 T 06-07-2017 CAL12_RS24780 fe782762e55e5a2c26efc0c9a589f500 454 Pfam PF01523 Putative modulator of DNA gyrase 39 327 5.6E-56 T 06-07-2017 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CAL12_RS13395 293ab8dd8cacb64158037f0e9ab413be 356 Gene3D G3DSA:3.50.30.50 98 133 1.2E-21 T 06-07-2017 CAL12_RS13395 293ab8dd8cacb64158037f0e9ab413be 356 Gene3D G3DSA:3.50.30.50 178 356 1.2E-21 T 06-07-2017 CAL12_RS13395 293ab8dd8cacb64158037f0e9ab413be 356 Pfam PF04199 Putative cyclase 94 279 6.3E-14 T 06-07-2017 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734 CAL12_RS13395 293ab8dd8cacb64158037f0e9ab413be 356 SUPERFAMILY SSF102198 100 130 8.76E-11 T 06-07-2017 CAL12_RS13395 293ab8dd8cacb64158037f0e9ab413be 356 SUPERFAMILY SSF102198 172 355 8.76E-11 T 06-07-2017 CAL12_RS05325 8912d24d491248062b38f01a95b34303 1337 Gene3D G3DSA:2.60.40.920 36 101 1.7E-4 T 06-07-2017 IPR003344 Big-1 (bacterial Ig-like domain 1) domain CAL12_RS05325 8912d24d491248062b38f01a95b34303 1337 SUPERFAMILY SSF49373 19 101 9.02E-6 T 06-07-2017 IPR008964 Invasin/intimin cell-adhesion fragments CAL12_RS23035 5df8de7623096d88d6fa00606d333dc0 295 Gene3D G3DSA:3.90.550.10 74 121 1.0E-7 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS23035 5df8de7623096d88d6fa00606d333dc0 295 SUPERFAMILY SSF53448 1 198 3.37E-14 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS06715 e2336db102c8ceaa7d238925febcbaeb 355 PIRSF PIRSF000296 15 343 8.2E-121 T 06-07-2017 IPR024168 Catalase, SrpA-type, predicted CAL12_RS06715 e2336db102c8ceaa7d238925febcbaeb 355 Gene3D G3DSA:2.40.180.10 45 343 3.5E-69 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS06715 e2336db102c8ceaa7d238925febcbaeb 355 Pfam PF00199 Catalase 64 340 4.6E-15 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS06715 e2336db102c8ceaa7d238925febcbaeb 355 SMART SM01060 26 350 9.3E-4 T 06-07-2017 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS06715 e2336db102c8ceaa7d238925febcbaeb 355 SUPERFAMILY SSF56634 30 341 5.63E-80 T 06-07-2017 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-74259 CAL12_RS06520 52f9b4e664933b40049666f3d5d06aec 213 Gene3D G3DSA:3.40.50.1240 1 208 7.4E-61 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS06520 52f9b4e664933b40049666f3d5d06aec 213 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 200 9.1E-62 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS06520 52f9b4e664933b40049666f3d5d06aec 213 SMART SM00855 3 161 7.3E-23 T 06-07-2017 IPR013078 Histidine phosphatase superfamily, clade-1 CAL12_RS06520 52f9b4e664933b40049666f3d5d06aec 213 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 06-07-2017 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CAL12_RS06520 52f9b4e664933b40049666f3d5d06aec 213 SUPERFAMILY SSF53254 1 206 1.31E-59 T 06-07-2017 IPR029033 Histidine phosphatase superfamily CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 Gene3D G3DSA:1.10.10.10 9 92 3.5E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 SUPERFAMILY SSF53850 96 300 1.45E-38 T 06-07-2017 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 Pfam PF03466 LysR substrate binding domain 94 297 4.8E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 Gene3D G3DSA:3.40.190.10 95 182 1.3E-17 T 06-07-2017 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 SUPERFAMILY SSF46785 7 117 8.11E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 4.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 4.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 4.1E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 Gene3D G3DSA:3.40.190.10 183 268 1.4E-14 T 06-07-2017 CAL12_RS07880 52ac8ca8b3ab4987ea102ca7bef3faf9 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.3E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 SUPERFAMILY SSF53850 84 291 9.23E-35 T 06-07-2017 CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 Gene3D G3DSA:1.10.10.10 1 80 2.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 Gene3D G3DSA:3.40.190.10 171 257 2.7E-18 T 06-07-2017 CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 3.3E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 SUPERFAMILY SSF46785 1 81 9.62E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 Gene3D G3DSA:3.40.190.10 86 170 1.3E-15 T 06-07-2017 CAL12_RS15785 8f3ddec46b2f04099972413ac779a815 311 Pfam PF03466 LysR substrate binding domain 83 288 5.8E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13130 f55f6149f50543f46069f3e89209d1cb 326 PIRSF PIRSF017082 1 325 2.5E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13130 f55f6149f50543f46069f3e89209d1cb 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 321 3.7E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13130 f55f6149f50543f46069f3e89209d1cb 326 SUPERFAMILY SSF53850 114 282 1.25E-11 T 06-07-2017 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 38 537 6.7E-209 T 06-07-2017 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 46 487 5.5E-136 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 Gene3D G3DSA:1.20.210.10 31 543 3.8E-177 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 265 319 - T 06-07-2017 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 SUPERFAMILY SSF81442 35 537 2.09E-166 T 06-07-2017 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 396 415 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 84 107 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 263 284 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 309 324 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 368 386 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 37 62 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 112 136 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 212 231 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 333 354 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 153 165 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 183 201 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS14890 8e000f79f56e6c79ee2c2de81d6f7e70 551 PRINTS PR01165 Cytochrome c oxidase subunit I signature 446 467 1.3E-94 T 06-07-2017 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS22890 7352b9dcb6169391e51ae8d302c47d24 357 Gene3D G3DSA:2.130.10.10 4 355 4.7E-92 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS22890 7352b9dcb6169391e51ae8d302c47d24 357 SUPERFAMILY SSF51004 20 354 1.23E-38 T 06-07-2017 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CAL12_RS22890 7352b9dcb6169391e51ae8d302c47d24 357 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 355 9.6E-97 T 06-07-2017 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31 CAL12_RS22655 55beabac7b8ed8cff12534c03d67c5cf 316 Gene3D G3DSA:1.10.3470.10 5 314 7.3E-90 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS22655 55beabac7b8ed8cff12534c03d67c5cf 316 Pfam PF01032 FecCD transport family 5 312 8.5E-81 T 06-07-2017 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CAL12_RS22655 55beabac7b8ed8cff12534c03d67c5cf 316 SUPERFAMILY SSF81345 8 313 1.44E-70 T 06-07-2017 IPR029022 ABC transporter, BtuC-like CAL12_RS25995 2a01f1f6e58ecdc469d39c9181345413 337 SUPERFAMILY SSF161111 40 235 6.67E-54 T 06-07-2017 CAL12_RS25995 2a01f1f6e58ecdc469d39c9181345413 337 Pfam PF01545 Cation efflux family 46 234 3.7E-45 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAL12_RS25995 2a01f1f6e58ecdc469d39c9181345413 337 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 40 315 8.5E-83 T 06-07-2017 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CAL12_RS25995 2a01f1f6e58ecdc469d39c9181345413 337 Gene3D G3DSA:1.20.1510.10 40 234 1.1E-58 T 06-07-2017 IPR027469 Cation efflux protein transmembrane domain CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 Gene3D G3DSA:3.40.309.10 264 444 2.1E-65 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 Gene3D G3DSA:3.40.605.10 6 263 3.8E-98 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 Pfam PF00171 Aldehyde dehydrogenase family 22 479 2.7E-136 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 483 9.1E-210 T 06-07-2017 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CAL12_RS08465 54daf16aadbbbb16ac9beb415bda49f9 497 SUPERFAMILY SSF53720 5 483 3.27E-144 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS18550 3e440f5904620671441e5c6126c44060 163 Gene3D G3DSA:3.30.240.20 94 161 9.5E-19 T 06-07-2017 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain CAL12_RS18550 3e440f5904620671441e5c6126c44060 163 Pfam PF04239 Protein of unknown function (DUF421) 103 161 6.5E-15 T 06-07-2017 IPR007353 Protein of unknown function DUF421 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 SUPERFAMILY SSF51905 223 293 8.82E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 SUPERFAMILY SSF51905 4 119 8.82E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 Gene3D G3DSA:3.50.50.60 121 189 4.5E-5 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 2.0E-21 T 06-07-2017 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 2.0E-21 T 06-07-2017 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 236 2.0E-21 T 06-07-2017 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.0E-21 T 06-07-2017 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.0E-21 T 06-07-2017 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 Gene3D G3DSA:3.50.50.60 228 296 7.1E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 Gene3D G3DSA:3.50.50.60 2 120 7.1E-32 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 274 5.9E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 1.0E-18 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 1.0E-18 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.0E-18 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS25855 ded9f22a4eaa179c4b14066e7ec9090d 299 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 295 1.0E-18 T 06-07-2017 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CAL12_RS12470 9e6f59d5c55303256feaec303c017d04 276 Gene3D G3DSA:3.20.20.70 1 252 7.3E-127 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS12470 9e6f59d5c55303256feaec303c017d04 276 SUPERFAMILY SSF51621 3 197 3.77E-81 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS12470 9e6f59d5c55303256feaec303c017d04 276 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 9 274 4.4E-130 T 06-07-2017 IPR009215 TIM-barrel domain, IGPS-like CAL12_RS12470 9e6f59d5c55303256feaec303c017d04 276 PIRSF PIRSF034452 1 276 1.1E-152 T 06-07-2017 IPR009215 TIM-barrel domain, IGPS-like CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 Gene3D G3DSA:3.20.20.110 138 421 1.5E-80 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 420 1.9E-82 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 Gene3D G3DSA:3.30.70.150 6 136 1.5E-36 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 18 132 5.6E-7 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 SUPERFAMILY SSF51649 139 421 1.7E-90 T 06-07-2017 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 SUPERFAMILY SSF54966 6 136 4.32E-34 T 06-07-2017 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS26510 4ef11839b92474651dae30d0af7cac10 421 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 184 192 - T 06-07-2017 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CAL12_RS21925 b17f2048ed132c46f75eb2b6b9914d23 643 SUPERFAMILY SSF48452 65 240 5.9E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21925 b17f2048ed132c46f75eb2b6b9914d23 643 Gene3D G3DSA:1.25.40.10 55 163 6.5E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21925 b17f2048ed132c46f75eb2b6b9914d23 643 Gene3D G3DSA:1.25.40.10 199 361 1.1E-17 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21925 b17f2048ed132c46f75eb2b6b9914d23 643 SUPERFAMILY SSF48452 247 412 9.16E-15 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS18650 8b5347e3d41773e003bff49fcdc463db 157 Pfam PF03061 Thioesterase superfamily 64 136 3.1E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS18650 8b5347e3d41773e003bff49fcdc463db 157 Gene3D G3DSA:3.10.129.10 17 149 8.1E-48 T 06-07-2017 IPR029069 HotDog domain CAL12_RS18650 8b5347e3d41773e003bff49fcdc463db 157 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 34 146 7.9E-50 T 06-07-2017 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 CAL12_RS18650 8b5347e3d41773e003bff49fcdc463db 157 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 33 144 1.2E-24 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAL12_RS18650 8b5347e3d41773e003bff49fcdc463db 157 SUPERFAMILY SSF54637 22 145 1.22E-30 T 06-07-2017 IPR029069 HotDog domain CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 Gene3D G3DSA:1.20.1250.20 261 454 1.6E-18 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 SUPERFAMILY SSF103473 245 453 7.85E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 SUPERFAMILY SSF103473 12 199 7.85E-57 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 Gene3D G3DSA:1.20.1250.20 13 179 9.1E-24 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 5.2E-10 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 396 415 5.2E-10 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 5.2E-10 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 13 37 5.2E-10 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 5.2E-10 T 06-07-2017 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 Pfam PF07690 Major Facilitator Superfamily 14 179 3.6E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS22935 d8d342a57614c59ca771c866fa585f0f 463 Pfam PF07690 Major Facilitator Superfamily 271 445 2.0E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS11425 fc282060e881e4d779efbd6074507aeb 208 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 127 3.5E-27 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11425 fc282060e881e4d779efbd6074507aeb 208 Pfam PF16184 Cadherin-like 100 207 4.2E-11 T 06-07-2017 CAL12_RS27185 b1fd615b363b09035db8cff6312fd3d3 112 SUPERFAMILY SSF46785 56 111 1.91E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27185 b1fd615b363b09035db8cff6312fd3d3 112 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 58 111 3.4E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27185 b1fd615b363b09035db8cff6312fd3d3 112 Gene3D G3DSA:1.10.10.10 55 111 7.5E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27530 fe37b8d5d12d8e658958449dd668c773 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 19.952 T 06-07-2017 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CAL12_RS27530 fe37b8d5d12d8e658958449dd668c773 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 5.2E-48 T 06-07-2017 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27530 fe37b8d5d12d8e658958449dd668c773 146 Gene3D G3DSA:3.100.10.10 35 145 8.7E-26 T 06-07-2017 CAL12_RS27530 fe37b8d5d12d8e658958449dd668c773 146 SUPERFAMILY SSF52080 7 144 2.75E-46 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAL12_RS27530 fe37b8d5d12d8e658958449dd668c773 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 145 7.6E-30 T 06-07-2017 IPR021131 Ribosomal protein L18e/L15P CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 SUPERFAMILY SSF51161 49 344 1.79E-73 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 12 354 36.067 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 228 244 0.037 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 287 320 0.011 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Gene3D G3DSA:2.160.10.10 132 236 4.2E-25 T 06-07-2017 CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 253 281 - T 06-07-2017 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 39 357 8.8E-102 T 06-07-2017 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Gene3D G3DSA:2.160.10.10 237 331 1.8E-19 T 06-07-2017 CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 250 285 2.8E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 175 5.3E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS12165 374f425ccd5844ff2671801810361bb2 364 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 39 111 6.3E-23 T 06-07-2017 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 21 293 4.1E-65 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 SMART SM01130 13 297 6.1E-89 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 Pfam PF00701 Dihydrodipicolinate synthetase family 14 294 1.1E-51 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 13 295 44.328 T 06-07-2017 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 06-07-2017 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 49 66 - T 06-07-2017 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 Gene3D G3DSA:3.20.20.70 13 296 1.9E-82 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 SUPERFAMILY SSF51569 11 296 3.24E-77 T 06-07-2017 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 PIRSF PIRSF001365 11 299 2.6E-71 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 5.7E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 5.7E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 5.7E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS27095 89fdd1bc433d06ffcd3b2be38f0725d1 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 5.7E-14 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS00340 0e9cf6fa3181240b6c3a79dbe5441b81 435 SUPERFAMILY SSF75304 4 424 1.96E-102 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS00340 0e9cf6fa3181240b6c3a79dbe5441b81 435 Pfam PF01425 Amidase 26 417 3.7E-65 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS00340 0e9cf6fa3181240b6c3a79dbe5441b81 435 Gene3D G3DSA:3.90.1300.10 7 423 9.2E-104 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS26825 9dd8b5213a8d2beed98d62f8c8ac8afc 281 Gene3D G3DSA:3.40.50.300 21 249 1.3E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26825 9dd8b5213a8d2beed98d62f8c8ac8afc 281 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS26825 9dd8b5213a8d2beed98d62f8c8ac8afc 281 Pfam PF00005 ABC transporter 39 188 1.8E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26825 9dd8b5213a8d2beed98d62f8c8ac8afc 281 SUPERFAMILY SSF52540 21 255 3.62E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26825 9dd8b5213a8d2beed98d62f8c8ac8afc 281 SMART SM00382 47 236 5.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02405 d250f0cf1de590a1a7575688f668b4c2 379 Pfam PF05977 Transmembrane secretion effector 8 367 7.9E-33 T 06-07-2017 IPR010290 Transmembrane secretion effector CAL12_RS02405 d250f0cf1de590a1a7575688f668b4c2 379 Gene3D G3DSA:1.20.1250.20 193 373 2.2E-12 T 06-07-2017 CAL12_RS02405 d250f0cf1de590a1a7575688f668b4c2 379 Gene3D G3DSA:1.20.1250.20 2 166 3.0E-19 T 06-07-2017 CAL12_RS02405 d250f0cf1de590a1a7575688f668b4c2 379 SUPERFAMILY SSF103473 2 374 2.88E-40 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 Pfam PF00355 Rieske [2Fe-2S] domain 55 140 3.4E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 SUPERFAMILY SSF50022 22 172 3.93E-47 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 SUPERFAMILY SSF55961 186 427 4.08E-44 T 06-07-2017 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 208 427 5.4E-16 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 Gene3D G3DSA:3.90.380.10 164 428 2.2E-49 T 06-07-2017 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 Gene3D G3DSA:2.102.10.10 55 163 4.9E-23 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 98 121 - T 06-07-2017 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 199 221 4.3E-27 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 70 85 4.3E-27 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 112 132 4.3E-27 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 91 111 4.3E-27 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAL12_RS12845 8becd3701ff90fa79a3708c871c78ab1 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 160 186 4.3E-27 T 06-07-2017 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CAL12_RS05675 25144106f10160541635e79c344cf43e 279 SUPERFAMILY SSF53448 2 269 8.67E-65 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS05675 25144106f10160541635e79c344cf43e 279 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 1.5E-112 T 06-07-2017 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 CAL12_RS05675 25144106f10160541635e79c344cf43e 279 Pfam PF00483 Nucleotidyl transferase 11 268 9.5E-30 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAL12_RS05675 25144106f10160541635e79c344cf43e 279 Gene3D G3DSA:3.90.550.10 5 271 5.2E-70 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS27960 988d85c831b61764698c1dd966effe3f 451 Gene3D G3DSA:3.30.1330.120 264 402 5.9E-31 T 06-07-2017 CAL12_RS27960 988d85c831b61764698c1dd966effe3f 451 Pfam PF03972 MmgE/PrpD family 5 435 3.0E-114 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27960 988d85c831b61764698c1dd966effe3f 451 SUPERFAMILY SSF103378 15 436 4.71E-104 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 4.8E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 Pfam PF07729 FCD domain 76 198 1.3E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 SMART SM00345 8 66 5.8E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 SMART SM00895 76 199 4.2E-18 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 Gene3D G3DSA:1.10.10.10 5 67 1.1E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 SUPERFAMILY SSF48008 73 205 1.26E-27 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 Gene3D G3DSA:1.20.120.530 70 205 1.5E-29 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS10420 2bc39bf4ca3433558befbb64d4e3c9dc 241 SUPERFAMILY SSF46785 6 70 3.09E-14 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 SMART SM00138 2 257 7.7E-40 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 PRINTS PR00996 Glutamate methyltransferase family signature 216 239 1.9E-20 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 PRINTS PR00996 Glutamate methyltransferase family signature 197 211 1.9E-20 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 PRINTS PR00996 Glutamate methyltransferase family signature 59 71 1.9E-20 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 PRINTS PR00996 Glutamate methyltransferase family signature 128 144 1.9E-20 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 PRINTS PR00996 Glutamate methyltransferase family signature 95 115 1.9E-20 T 06-07-2017 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 238 6.6E-38 T 06-07-2017 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 SUPERFAMILY SSF48452 356 436 4.56E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 SUPERFAMILY SSF53335 66 250 3.93E-41 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 Gene3D G3DSA:1.25.40.10 352 442 2.4E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS19060 231b7bc57154a54d4882793b0e262f56 450 Gene3D G3DSA:3.40.50.150 66 251 6.2E-50 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02125 af5672a4986f8705b304605a13719f7a 129 SUPERFAMILY SSF46785 3 128 1.53E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02125 af5672a4986f8705b304605a13719f7a 129 Pfam PF13412 Winged helix-turn-helix DNA-binding 44 70 2.7E-5 T 06-07-2017 CAL12_RS02125 af5672a4986f8705b304605a13719f7a 129 Gene3D G3DSA:1.10.10.10 3 129 1.3E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 Gene3D G3DSA:3.40.50.720 1 247 1.2E-89 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 5.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.5E-13 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 187 0.0016 T 06-07-2017 CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 6.2E-70 T 06-07-2017 CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.1E-45 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS03710 2837ab6d0fe7a4a5f4ad23569d1204a5 254 SUPERFAMILY SSF51735 5 246 4.79E-84 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 10 169 5.0E-80 T 06-07-2017 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 153 1.8E-36 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 PIRSF PIRSF006443 1 167 2.0E-64 T 06-07-2017 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 Pfam PF00994 Probable molybdopterin binding domain 15 156 2.0E-34 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 SMART SM00852 15 159 2.3E-30 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 SUPERFAMILY SSF53218 11 169 1.96E-46 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 73 86 - T 06-07-2017 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CAL12_RS23925 0a7a8443a447d630399000fb9f334880 182 Gene3D G3DSA:3.40.980.10 9 170 8.5E-49 T 06-07-2017 IPR001453 MoaB/Mog domain CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 187 1.4E-77 T 06-07-2017 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 Gene3D G3DSA:3.40.50.880 2 187 6.7E-66 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 1.4E-6 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 1.4E-6 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.1E-13 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 2.1E-13 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 2.1E-13 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 Pfam PF00117 Glutamine amidotransferase class-I 5 186 6.4E-53 T 06-07-2017 IPR017926 Glutamine amidotransferase CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 48 57 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 75 86 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 120 132 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 100 108 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 PRINTS PR00097 Anthranilate synthase component II signature 165 178 2.6E-33 T 06-07-2017 CAL12_RS26110 5a2cf26c4299b138222bc493051704d2 189 SUPERFAMILY SSF52317 3 187 2.39E-55 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS11880 653a77d58f93a51f1460557eb625c3ca 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 2 92 4.1E-17 T 06-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CAL12_RS11880 653a77d58f93a51f1460557eb625c3ca 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 89 1.8E-10 T 06-07-2017 IPR031316 Anti-sigma-28 factor FlgM, C-terminal CAL12_RS11880 653a77d58f93a51f1460557eb625c3ca 97 SUPERFAMILY SSF101498 4 90 5.23E-12 T 06-07-2017 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 Gene3D G3DSA:3.40.50.300 198 304 1.4E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 Gene3D G3DSA:3.40.50.300 546 558 1.4E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 Gene3D G3DSA:3.40.50.300 353 418 1.4E-10 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 SMART SM00491 629 764 6.4E-15 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 Pfam PF06733 DEAD_2 292 410 2.6E-9 T 06-07-2017 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 SUPERFAMILY SSF52540 544 558 6.29E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 SUPERFAMILY SSF52540 587 759 6.29E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 SUPERFAMILY SSF52540 338 411 6.29E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 SUPERFAMILY SSF52540 219 270 6.29E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07215 95720fec75ad6f88082dca891d15a9ff 793 Pfam PF13307 Helicase C-terminal domain 614 777 1.5E-30 T 06-07-2017 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CAL12_RS09100 ef72650f2ba3f0fe3a8915065b65dc9c 132 Pfam PF06339 Ectoine synthase 1 127 3.9E-58 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS09100 ef72650f2ba3f0fe3a8915065b65dc9c 132 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 5.0E-62 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS09100 ef72650f2ba3f0fe3a8915065b65dc9c 132 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 39.914 T 06-07-2017 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CAL12_RS09100 ef72650f2ba3f0fe3a8915065b65dc9c 132 SUPERFAMILY SSF51182 1 128 3.24E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS09100 ef72650f2ba3f0fe3a8915065b65dc9c 132 Gene3D G3DSA:2.60.120.10 15 111 4.5E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS25865 3b60ed6313fbb8b5ebcea617828a1e30 334 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 30 291 56.344 T 06-07-2017 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 Reactome: R-HSA-6782315 CAL12_RS25865 3b60ed6313fbb8b5ebcea617828a1e30 334 Pfam PF01171 PP-loop family 62 225 7.1E-13 T 06-07-2017 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CAL12_RS25865 3b60ed6313fbb8b5ebcea617828a1e30 334 Gene3D G3DSA:3.40.50.620 45 227 1.1E-20 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS25865 3b60ed6313fbb8b5ebcea617828a1e30 334 SUPERFAMILY SSF52402 37 256 2.26E-53 T 06-07-2017 CAL12_RS09400 f88373630dc0f7a785fe23dab1bd9bd9 45 Pfam PF08085 Entericidin EcnA/B family 21 41 7.2E-10 T 06-07-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 SUPERFAMILY SSF56719 416 661 2.04E-74 T 06-07-2017 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 44 57 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 156 170 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 213 234 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 338 353 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 475 496 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 195 212 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 321 337 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 389 414 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR01098 Topoisomerase IV subunit B signature 365 388 2.2E-37 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 84 97 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 528 545 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 293 306 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 600 616 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 441 455 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 548 560 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 49 64 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 130 144 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 PRINTS PR00418 DNA topoisomerase II family signature 510 526 1.7E-59 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Gene3D G3DSA:3.30.565.10 33 234 6.2E-70 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 SMART SM00433 51 664 7.6E-197 T 06-07-2017 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Gene3D G3DSA:3.40.50.670 425 649 1.5E-76 T 06-07-2017 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 52 192 2.4E-18 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 20 668 44.616 T 06-07-2017 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 SUPERFAMILY SSF55874 22 236 4.85E-61 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 596 660 2.1E-25 T 06-07-2017 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Gene3D G3DSA:3.30.230.10 238 417 9.8E-36 T 06-07-2017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 SMART SM00387 46 194 9.1E-19 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Pfam PF01751 Toprim domain 440 554 6.4E-12 T 06-07-2017 IPR006171 Toprim domain CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 Pfam PF00204 DNA gyrase B 239 411 3.6E-32 T 06-07-2017 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 SUPERFAMILY SSF54211 239 412 1.63E-35 T 06-07-2017 IPR020568 Ribosomal protein S5 domain 2-type fold CAL12_RS09075 a2afbae8c361b0cd6b6144be92572e26 670 ProSitePatterns PS00177 DNA topoisomerase II signature. 443 451 - T 06-07-2017 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CAL12_RS02895 125413679b01a89836ed79b094a2090f 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 4.0E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS02895 125413679b01a89836ed79b094a2090f 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 4.0E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS02895 125413679b01a89836ed79b094a2090f 372 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 4.0E-6 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS02895 125413679b01a89836ed79b094a2090f 372 Pfam PF12698 ABC-2 family transporter protein 31 364 6.9E-41 T 06-07-2017 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 SMART SM00062 34 263 4.3E-41 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 Gene3D G3DSA:3.40.190.10 224 253 1.5E-17 T 06-07-2017 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 Gene3D G3DSA:3.40.190.10 31 125 1.5E-17 T 06-07-2017 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 Gene3D G3DSA:3.40.190.10 126 223 1.1E-15 T 06-07-2017 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 SUPERFAMILY SSF53850 25 258 5.22E-48 T 06-07-2017 CAL12_RS25255 f66b91ed42cdaf36f0a5f22c6c36e049 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 1.7E-32 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS17735 3ab54a3177764efce8894a56a929c951 271 Pfam PF01925 Sulfite exporter TauE/SafE 9 262 1.0E-50 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 Gene3D G3DSA:3.40.50.720 172 287 8.5E-29 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 Gene3D G3DSA:3.90.180.10 3 171 6.5E-38 T 06-07-2017 IPR011032 GroES-like CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 SUPERFAMILY SSF51735 143 314 3.07E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 Pfam PF00107 Zinc-binding dehydrogenase 177 300 5.2E-25 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 SUPERFAMILY SSF50129 3 172 5.78E-38 T 06-07-2017 IPR011032 GroES-like CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 SMART SM00829 14 337 1.3E-14 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS16125 c60e4862a46b1b93b5824dbe964f3955 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 133 2.6E-10 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS26335 094d807a07efeee3718215cb8961eb5d 246 Pfam PF01965 DJ-1/PfpI family 23 183 5.6E-33 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS26335 094d807a07efeee3718215cb8961eb5d 246 Gene3D G3DSA:3.40.50.880 23 234 1.0E-66 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26335 094d807a07efeee3718215cb8961eb5d 246 SUPERFAMILY SSF52317 23 203 2.5E-51 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 Pfam PF00083 Sugar (and other) transporter 24 333 6.9E-29 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 Gene3D G3DSA:1.20.1250.20 17 218 2.1E-25 T 06-07-2017 CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 Gene3D G3DSA:1.20.1250.20 434 531 1.8E-25 T 06-07-2017 CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 Gene3D G3DSA:1.20.1250.20 247 335 1.8E-25 T 06-07-2017 CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 SUPERFAMILY SSF103473 16 336 7.85E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 SUPERFAMILY SSF103473 438 528 7.85E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS21040 70e2a04e3a0f19d32043834128ccc618 545 ProSitePatterns PS00216 Sugar transport proteins signature 1. 301 317 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 Pfam PF03797 Autotransporter beta-domain 972 1219 8.7E-44 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 1105 1122 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 1153 1174 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 1216 1236 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 1191 1216 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 940 958 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 PRINTS PR01484 Pertactin virulence factor family signature 1124 1147 5.3E-23 T 06-07-2017 IPR003991 Pertactin virulence factor family GO:0007155 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 Pfam PF03212 Pertactin 521 618 3.3E-14 T 06-07-2017 IPR004899 Pertactin, central region CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 SUPERFAMILY SSF103515 933 1236 1.02E-48 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 524 622 9.7E-7 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 908 1236 5.9E-62 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 SMART SM00869 973 1225 1.6E-42 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 SUPERFAMILY SSF51126 520 603 7.85E-24 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 SUPERFAMILY SSF51126 237 490 7.85E-24 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 Gene3D G3DSA:2.160.20.20 83 182 1.7E-34 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 Gene3D G3DSA:2.160.20.20 232 617 1.7E-34 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23255 fb277670d33097400f3da24a41674bb3 1236 Gene3D G3DSA:2.40.128.130 929 1236 3.6E-73 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Pfam PF00005 ABC transporter 305 459 9.0E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Pfam PF00005 ABC transporter 32 183 2.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 ProSitePatterns PS00211 ABC transporters family signature. 432 446 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Gene3D G3DSA:3.40.50.300 5 258 7.5E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Gene3D G3DSA:3.40.50.300 281 534 3.4E-75 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 SMART SM00382 40 233 1.6E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 SMART SM00382 312 509 1.2E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 SUPERFAMILY SSF52540 11 255 6.03E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 SUPERFAMILY SSF52540 278 538 3.28E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 511 543 3.9E-6 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 269 2.9E-4 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS23465 3da27842da18e7e4469405ae801f06dd 566 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 Gene3D G3DSA:1.20.1280.20 82 167 5.3E-21 T 06-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 SUPERFAMILY SSF47144 78 167 7.59E-17 T 06-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 SMART SM00271 2 67 8.1E-4 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 14 167 7.7E-26 T 06-07-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 164 4.4E-15 T 06-07-2017 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020 CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 SUPERFAMILY SSF46565 3 73 2.09E-17 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 Gene3D G3DSA:1.10.287.110 3 73 5.2E-25 T 06-07-2017 IPR001623 DnaJ domain CAL12_RS17160 5f2b382263a86a8af7bd3190c7a4dedc 169 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 2 169 20.496 T 06-07-2017 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 Reactome: R-HSA-1268020 CAL12_RS19770 7172837feed748fed0c52abb37e5dfc1 142 Pfam PF11162 Protein of unknown function (DUF2946) 19 140 3.3E-9 T 06-07-2017 IPR021333 Protein of unknown function DUF2946 CAL12_RS20770 09bbac6cd6c7be6292b016a2c8ee88e5 320 PIRSF PIRSF017082 1 320 1.3E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20770 09bbac6cd6c7be6292b016a2c8ee88e5 320 SUPERFAMILY SSF53850 111 282 1.06E-10 T 06-07-2017 CAL12_RS20770 09bbac6cd6c7be6292b016a2c8ee88e5 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 317 2.3E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 SUPERFAMILY SSF52540 39 197 2.78E-29 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 ProSitePatterns PS01128 Shikimate kinase signature. 92 117 - T 06-07-2017 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 Gene3D G3DSA:3.40.50.300 37 203 4.7E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 Hamap MF_00109 Shikimate kinase [aroK]. 36 202 29.016 T 06-07-2017 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 Pfam PF01202 Shikimate kinase 45 199 6.9E-50 T 06-07-2017 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 PRINTS PR01100 Shikimate kinase family signature 109 118 4.7E-25 T 06-07-2017 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 PRINTS PR01100 Shikimate kinase family signature 39 54 4.7E-25 T 06-07-2017 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 PRINTS PR01100 Shikimate kinase family signature 91 99 4.7E-25 T 06-07-2017 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 PRINTS PR01100 Shikimate kinase family signature 130 147 4.7E-25 T 06-07-2017 CAL12_RS27430 38794fced18e88d892a4e749bd2dd234 208 PRINTS PR01100 Shikimate kinase family signature 63 76 4.7E-25 T 06-07-2017 CAL12_RS17565 6d9f9756d3e135663325c70d3b61b448 392 Gene3D G3DSA:1.20.1090.10 186 391 2.6E-60 T 06-07-2017 CAL12_RS17565 6d9f9756d3e135663325c70d3b61b448 392 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 383 3.3E-105 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAL12_RS17565 6d9f9756d3e135663325c70d3b61b448 392 SUPERFAMILY SSF56796 3 390 1.11E-108 T 06-07-2017 CAL12_RS17565 6d9f9756d3e135663325c70d3b61b448 392 Gene3D G3DSA:3.40.50.1970 1 185 1.1E-45 T 06-07-2017 CAL12_RS17565 6d9f9756d3e135663325c70d3b61b448 392 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 SMART SM00062 62 281 1.9E-31 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 Gene3D G3DSA:3.40.190.10 140 238 6.7E-12 T 06-07-2017 CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 SUPERFAMILY SSF53850 63 276 2.17E-44 T 06-07-2017 CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 63 275 5.6E-35 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 Gene3D G3DSA:3.40.190.10 243 276 2.1E-22 T 06-07-2017 CAL12_RS01225 4a3c1efa778ece74bffd84b642f41bfc 299 Gene3D G3DSA:3.40.190.10 60 139 2.1E-22 T 06-07-2017 CAL12_RS13515 222f4051f1a1c04e2bbb33e37cb673d5 411 Gene3D G3DSA:1.20.1250.20 20 192 7.6E-22 T 06-07-2017 CAL12_RS13515 222f4051f1a1c04e2bbb33e37cb673d5 411 Gene3D G3DSA:1.20.1250.20 216 397 8.5E-13 T 06-07-2017 CAL12_RS13515 222f4051f1a1c04e2bbb33e37cb673d5 411 SUPERFAMILY SSF103473 12 397 1.01E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS13515 222f4051f1a1c04e2bbb33e37cb673d5 411 Pfam PF07690 Major Facilitator Superfamily 24 323 7.0E-30 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 8.6E-42 T 06-07-2017 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Gene3D G3DSA:3.40.47.10 277 392 2.1E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Gene3D G3DSA:3.40.47.10 143 195 2.1E-55 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 SUPERFAMILY SSF53901 271 392 1.93E-39 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 2.4E-125 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 SUPERFAMILY SSF53901 5 269 9.22E-76 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 06-07-2017 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Gene3D G3DSA:3.40.47.10 196 276 3.5E-71 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Gene3D G3DSA:3.40.47.10 5 124 3.5E-71 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 PIRSF PIRSF000429 1 393 1.5E-112 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS00535 a23a757d5c3aa5eb5fcc7291c80d7e5c 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 8.4E-87 T 06-07-2017 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 Pfam PF00203 Ribosomal protein S19 3 83 4.7E-38 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 PIRSF PIRSF002144 1 91 3.3E-34 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 2.4E-46 T 06-07-2017 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.6E-24 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 Gene3D G3DSA:3.30.860.10 1 90 3.9E-42 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 26.03 T 06-07-2017 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 06-07-2017 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27635 d9b9b14b6f83aac65801ef7b7ae5f687 91 SUPERFAMILY SSF54570 2 84 1.7E-36 T 06-07-2017 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 385 9.5E-79 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 SUPERFAMILY SSF111369 63 309 2.88E-66 T 06-07-2017 CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 70 304 2.5E-11 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 Pfam PF00529 HlyD membrane-fusion protein of T1SS 166 370 9.8E-7 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 Gene3D G3DSA:2.40.50.100 75 108 1.7E-13 T 06-07-2017 CAL12_RS22305 591d44003ad894cec8c0f69bb5ff9223 410 Gene3D G3DSA:2.40.50.100 183 209 1.7E-13 T 06-07-2017 CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 Pfam PF07729 FCD domain 107 225 2.3E-20 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 SUPERFAMILY SSF46785 24 100 4.96E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 Gene3D G3DSA:1.20.120.530 100 241 2.1E-21 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 88 1.1E-12 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 SMART SM00345 35 96 1.5E-6 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 SMART SM00895 106 230 1.3E-14 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 SUPERFAMILY SSF48008 104 237 3.66E-20 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS14790 59608794e66cd24aded66344ccfbb088 244 Gene3D G3DSA:1.10.10.10 20 88 4.6E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 SUPERFAMILY SSF51735 6 242 1.19E-76 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 0.0054 T 06-07-2017 CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 Gene3D G3DSA:3.40.50.720 2 242 1.6E-80 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.3E-8 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.2E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16930 f33c1da29c42c5f523003ed844357dfc 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 242 4.0E-65 T 06-07-2017 CAL12_RS15500 de53dd4c5d8cb6cd5ca5e4d77f1bef3f 353 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 227 3.0E-62 T 06-07-2017 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CAL12_RS15500 de53dd4c5d8cb6cd5ca5e4d77f1bef3f 353 Gene3D G3DSA:3.40.50.300 12 197 6.7E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15500 de53dd4c5d8cb6cd5ca5e4d77f1bef3f 353 Pfam PF13177 DNA polymerase III, delta subunit 20 196 3.6E-37 T 06-07-2017 CAL12_RS15500 de53dd4c5d8cb6cd5ca5e4d77f1bef3f 353 SUPERFAMILY SSF52540 11 83 7.09E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15500 de53dd4c5d8cb6cd5ca5e4d77f1bef3f 353 SUPERFAMILY SSF52540 114 230 7.09E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS11620 b3e359cfa6a0e73d5c4b36dcfe0443f6 348 SUPERFAMILY SSF53850 127 310 2.17E-14 T 06-07-2017 CAL12_RS11620 b3e359cfa6a0e73d5c4b36dcfe0443f6 348 PIRSF PIRSF017082 14 348 3.6E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11620 b3e359cfa6a0e73d5c4b36dcfe0443f6 348 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 72 345 6.1E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS09550 0d7907d8ef606563eb6d4f3deae7d49b 43 Pfam PF08085 Entericidin EcnA/B family 21 41 1.4E-10 T 06-07-2017 IPR012556 Entericidin A/B GO:0009636|GO:0016020 CAL12_RS06020 d520730af0f5b988f086a4bae224b27d 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 24 47 4.8E-7 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAL12_RS06020 d520730af0f5b988f086a4bae224b27d 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 57 111 9.1E-7 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAL12_RS06020 d520730af0f5b988f086a4bae224b27d 136 SUPERFAMILY SSF50249 19 112 4.11E-17 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 PIRSF PIRSF002741 10 540 2.0E-71 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 SUPERFAMILY SSF53850 31 537 7.53E-107 T 06-07-2017 CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 Gene3D G3DSA:3.10.105.10 310 511 2.1E-40 T 06-07-2017 CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 86 424 8.6E-72 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 Gene3D G3DSA:3.90.76.10 64 208 1.4E-25 T 06-07-2017 CAL12_RS02410 1fd6780144bad425f5f753e3e27f0b24 542 Gene3D G3DSA:3.40.190.10 209 309 1.5E-31 T 06-07-2017 CAL12_RS22985 61c69262a316d1a85e4432f0a7fad438 579 Pfam PF02543 Carbamoyltransferase N-terminus 4 353 1.7E-66 T 06-07-2017 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CAL12_RS22985 61c69262a316d1a85e4432f0a7fad438 579 SUPERFAMILY SSF53067 1 88 6.73E-18 T 06-07-2017 CAL12_RS22985 61c69262a316d1a85e4432f0a7fad438 579 SUPERFAMILY SSF53067 151 357 6.73E-18 T 06-07-2017 CAL12_RS22985 61c69262a316d1a85e4432f0a7fad438 579 Pfam PF16861 Carbamoyltransferase C-terminus 405 577 2.2E-69 T 06-07-2017 IPR031730 Carbamoyltransferase, C-terminal CAL12_RS24060 18d0aafcadc7f5905073911ae7f819bd 271 Gene3D G3DSA:3.20.20.140 2 271 4.2E-85 T 06-07-2017 CAL12_RS24060 18d0aafcadc7f5905073911ae7f819bd 271 Pfam PF04909 Amidohydrolase 8 271 8.7E-40 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS24060 18d0aafcadc7f5905073911ae7f819bd 271 SUPERFAMILY SSF51556 4 271 3.18E-74 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS27470 cfa877f7aa626660ced7914f9adbc2d0 207 SUPERFAMILY SSF52540 7 201 2.68E-32 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27470 cfa877f7aa626660ced7914f9adbc2d0 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 197 3.9E-59 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CAL12_RS27470 cfa877f7aa626660ced7914f9adbc2d0 207 Gene3D G3DSA:3.40.50.300 15 202 3.1E-34 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27470 cfa877f7aa626660ced7914f9adbc2d0 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 201 25.917 T 06-07-2017 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CAL12_RS27470 cfa877f7aa626660ced7914f9adbc2d0 207 Pfam PF01926 50S ribosome-binding GTPase 26 151 8.9E-17 T 06-07-2017 IPR006073 GTP binding domain GO:0005525 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 PRINTS PR00735 Glycosyl hydrolase family 8 signature 379 393 1.9E-13 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 PRINTS PR00735 Glycosyl hydrolase family 8 signature 70 83 1.9E-13 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 PRINTS PR00735 Glycosyl hydrolase family 8 signature 132 150 1.9E-13 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 PRINTS PR00735 Glycosyl hydrolase family 8 signature 275 284 1.9E-13 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 PRINTS PR00735 Glycosyl hydrolase family 8 signature 198 215 1.9E-13 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 Pfam PF01270 Glycosyl hydrolases family 8 29 393 5.1E-61 T 06-07-2017 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 Gene3D G3DSA:1.50.10.10 18 399 4.0E-82 T 06-07-2017 IPR012341 Six-hairpin glycosidase GO:0003824 CAL12_RS00280 61eacabc4a035ea208dcd5f93f4ecb61 418 SUPERFAMILY SSF48208 20 399 3.34E-85 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS11510 9842b61aced440f8d679171ee20d1f00 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 131 8.1E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS03670 e7d8e6d4ccbcbea549f19d9499089a12 258 SMART SM00382 33 214 1.1E-11 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS03670 e7d8e6d4ccbcbea549f19d9499089a12 258 SUPERFAMILY SSF52540 5 236 2.32E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03670 e7d8e6d4ccbcbea549f19d9499089a12 258 Gene3D G3DSA:3.40.50.300 4 219 3.6E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03670 e7d8e6d4ccbcbea549f19d9499089a12 258 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS03670 e7d8e6d4ccbcbea549f19d9499089a12 258 Pfam PF00005 ABC transporter 24 163 3.9E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS11715 2f4362669e0eb033d2ff6dc71fbe5ff8 204 Pfam PF02630 SCO1/SenC 43 176 2.0E-34 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS11715 2f4362669e0eb033d2ff6dc71fbe5ff8 204 SUPERFAMILY SSF52833 43 201 3.16E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS11715 2f4362669e0eb033d2ff6dc71fbe5ff8 204 Gene3D G3DSA:3.40.30.10 12 202 1.0E-50 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 Pfam PF03099 Biotin/lipoate A/B protein ligase family 91 191 7.9E-10 T 06-07-2017 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 SUPERFAMILY SSF55681 32 53 2.15E-32 T 06-07-2017 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 SUPERFAMILY SSF55681 80 251 2.15E-32 T 06-07-2017 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 Gene3D G3DSA:2.30.30.100 256 303 3.1E-10 T 06-07-2017 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 Pfam PF02237 Biotin protein ligase C terminal domain 256 301 7.6E-5 T 06-07-2017 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 80 299 7.7E-27 T 06-07-2017 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 Gene3D G3DSA:3.30.930.10 32 252 2.1E-38 T 06-07-2017 CAL12_RS26835 e8e4ec282a2cc41b29dfd1a4dd82735d 303 SUPERFAMILY SSF50037 256 301 7.78E-5 T 06-07-2017 IPR008988 Transcriptional repressor, C-terminal CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 Pfam PF00106 short chain dehydrogenase 16 215 1.8E-26 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 Gene3D G3DSA:3.40.50.720 13 251 2.1E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 39 56 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.9E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16760 a6f60be99f001d8aa5f2f782c6a4503e 304 SUPERFAMILY SSF51735 13 253 7.33E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01690 ac1447370ecb3f25319d92e57c14f0e5 290 SUPERFAMILY SSF52540 4 160 6.58E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01690 ac1447370ecb3f25319d92e57c14f0e5 290 PIRSF PIRSF005052 2 289 9.0E-111 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAL12_RS01690 ac1447370ecb3f25319d92e57c14f0e5 290 Gene3D G3DSA:3.40.50.300 4 161 1.7E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01690 ac1447370ecb3f25319d92e57c14f0e5 290 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 286 39.111 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAL12_RS01690 ac1447370ecb3f25319d92e57c14f0e5 290 Pfam PF03668 P-loop ATPase protein family 3 283 4.2E-88 T 06-07-2017 IPR005337 RapZ-like family GO:0005524 CAL12_RS12320 a84a4786e84c3da4a50af63e726987b5 193 Gene3D G3DSA:3.40.30.10 6 90 1.3E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS12320 a84a4786e84c3da4a50af63e726987b5 193 Gene3D G3DSA:1.20.1050.10 91 190 1.7E-11 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS12320 a84a4786e84c3da4a50af63e726987b5 193 SUPERFAMILY SSF52833 3 86 1.6E-13 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS12320 a84a4786e84c3da4a50af63e726987b5 193 SUPERFAMILY SSF47616 83 191 2.67E-7 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS12320 a84a4786e84c3da4a50af63e726987b5 193 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 80 2.6E-8 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS24850 3b47db737854cf64c7ca10c14373dece 311 SUPERFAMILY SSF53613 3 298 2.34E-63 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS24850 3b47db737854cf64c7ca10c14373dece 311 Pfam PF00294 pfkB family carbohydrate kinase 36 295 1.6E-42 T 06-07-2017 IPR011611 Carbohydrate kinase PfkB CAL12_RS24850 3b47db737854cf64c7ca10c14373dece 311 Gene3D G3DSA:3.40.1190.20 4 305 1.5E-57 T 06-07-2017 IPR029056 Ribokinase-like CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 Gene3D G3DSA:3.40.50.2300 21 150 1.3E-49 T 06-07-2017 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 Gene3D G3DSA:3.40.50.2300 297 359 1.3E-49 T 06-07-2017 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 Gene3D G3DSA:3.40.50.2300 151 296 1.6E-9 T 06-07-2017 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 Pfam PF13458 Periplasmic binding protein 25 378 8.0E-69 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 SUPERFAMILY SSF53822 25 389 5.38E-87 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 4.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 4.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 4.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS26465 4bec2987fedcc128ff90518238947a92 409 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 282 295 4.2E-9 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS02335 512501143a4e3d32abb5249fd56e0c16 137 Gene3D G3DSA:1.10.260.40 23 85 1.9E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS02335 512501143a4e3d32abb5249fd56e0c16 137 SUPERFAMILY SSF47413 23 79 1.83E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS02335 512501143a4e3d32abb5249fd56e0c16 137 Pfam PF13560 Helix-turn-helix domain 25 86 7.6E-9 T 06-07-2017 CAL12_RS02335 512501143a4e3d32abb5249fd56e0c16 137 SMART SM00530 29 83 1.1E-5 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 Gene3D G3DSA:3.40.50.300 1 211 7.5E-81 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 Gene3D G3DSA:3.40.50.300 212 369 3.5E-49 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 SUPERFAMILY SSF52540 73 361 2.29E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 Pfam PF00271 Helicase conserved C-terminal domain 235 340 1.6E-25 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 SMART SM00487 20 222 2.1E-57 T 06-07-2017 IPR014001 Helicase superfamily 1/2, ATP-binding domain CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 06-07-2017 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 SMART SM00490 259 340 3.1E-30 T 06-07-2017 IPR001650 Helicase, C-terminal CAL12_RS26560 448bc07738fba4c78b2cf35d49d3097b 579 Pfam PF00270 DEAD/DEAH box helicase 25 195 1.4E-48 T 06-07-2017 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CAL12_RS14530 c18b738418d91b5e8bac86c23ab1a743 327 PIRSF PIRSF017082 2 327 1.9E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14530 c18b738418d91b5e8bac86c23ab1a743 327 SUPERFAMILY SSF53850 97 286 3.41E-15 T 06-07-2017 CAL12_RS14530 c18b738418d91b5e8bac86c23ab1a743 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 4.1E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00430 9234c12e3b27311e7d325d213dde4a97 238 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 22 224 40.588 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS00430 9234c12e3b27311e7d325d213dde4a97 238 Gene3D G3DSA:3.90.870.10 27 221 2.7E-83 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS00430 9234c12e3b27311e7d325d213dde4a97 238 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 29 218 5.0E-75 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS00430 9234c12e3b27311e7d325d213dde4a97 238 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 27 220 1.1E-67 T 06-07-2017 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CAL12_RS00430 9234c12e3b27311e7d325d213dde4a97 238 SUPERFAMILY SSF55821 25 221 1.44E-76 T 06-07-2017 IPR017945 DHBP synthase RibB-like alpha/beta domain CAL12_RS13445 5d16e4e5f17193d51df6b7a6abb9021f 313 Gene3D G3DSA:1.10.3720.10 89 304 1.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13445 5d16e4e5f17193d51df6b7a6abb9021f 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 6.3E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13445 5d16e4e5f17193d51df6b7a6abb9021f 313 SUPERFAMILY SSF161098 92 296 1.05E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 Gene3D G3DSA:3.40.190.10 191 246 3.8E-10 T 06-07-2017 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 Gene3D G3DSA:3.40.190.10 88 190 6.2E-13 T 06-07-2017 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 Gene3D G3DSA:1.10.10.10 1 86 2.5E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.1E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 SUPERFAMILY SSF46785 1 87 7.56E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 Pfam PF03466 LysR substrate binding domain 87 284 2.4E-18 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS04060 4ec46e7fecd79dda5d33461e605ecabf 297 SUPERFAMILY SSF53850 86 287 7.74E-20 T 06-07-2017 CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 Gene3D G3DSA:1.20.1250.20 246 423 3.4E-18 T 06-07-2017 CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 Gene3D G3DSA:1.20.1250.20 16 226 3.6E-25 T 06-07-2017 CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 SUPERFAMILY SSF103473 13 430 3.92E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 Pfam PF00083 Sugar (and other) transporter 23 432 7.6E-36 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS01250 aebec7df155ba332991ade47389f423c 458 ProSitePatterns PS00216 Sugar transport proteins signature 1. 301 317 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS27210 538945597a3a847e2a77198ffaa9f500 171 Gene3D G3DSA:1.10.10.10 13 144 4.8E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27210 538945597a3a847e2a77198ffaa9f500 171 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS27210 538945597a3a847e2a77198ffaa9f500 171 SMART SM00347 31 133 1.2E-11 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS27210 538945597a3a847e2a77198ffaa9f500 171 SUPERFAMILY SSF46785 13 145 1.54E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27210 538945597a3a847e2a77198ffaa9f500 171 Pfam PF13463 Winged helix DNA-binding domain 53 106 1.7E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 SUPERFAMILY SSF52540 12 247 9.33E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 SMART SM00382 34 224 1.1 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 SMART SM00382 275 439 0.0027 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 PIRSF PIRSF039117 2 498 1.0E-114 T 06-07-2017 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 PRINTS PR01874 DNA repair protein radA signature 68 85 1.3E-6 T 06-07-2017 CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 PRINTS PR01874 DNA repair protein radA signature 26 54 1.3E-6 T 06-07-2017 CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 Gene3D G3DSA:3.40.50.300 248 491 1.2E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 Gene3D G3DSA:3.40.50.300 12 247 3.2E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 Pfam PF06745 KaiC 17 243 2.2E-38 T 06-07-2017 IPR014774 KaiC-like domain CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 Pfam PF06745 KaiC 260 477 2.6E-25 T 06-07-2017 IPR014774 KaiC-like domain CAL12_RS13490 595c108dc3fa55e7570fd33341d07a45 507 SUPERFAMILY SSF52540 257 486 2.9E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 Pfam PF00106 short chain dehydrogenase 7 192 7.1E-47 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 SUPERFAMILY SSF51735 5 241 3.12E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.3E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 Gene3D G3DSA:3.40.50.720 6 249 8.2E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS14300 b43e2fb3c043e7691d764edc43a59fe9 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.5E-23 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 SUPERFAMILY SSF52540 7 264 7.66E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 Pfam PF00005 ABC transporter 42 193 6.1E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 242 328 2.3E-28 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 Gene3D G3DSA:3.40.50.300 2 268 6.3E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 244 308 4.6E-18 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS25720 d8534a44f42abdf3ebedc63a65d2a931 336 SMART SM00382 50 242 5.2E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09765 a45163268b2a66e40887a10dcc37e33a 132 Pfam PF03610 PTS system fructose IIA component 3 111 4.9E-16 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAL12_RS09765 a45163268b2a66e40887a10dcc37e33a 132 Gene3D G3DSA:3.40.50.510 1 131 2.2E-30 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAL12_RS09765 a45163268b2a66e40887a10dcc37e33a 132 SUPERFAMILY SSF53062 1 131 1.7E-25 T 06-07-2017 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CAL12_RS02855 6d3b0fb7589cf6bc0cee49395d22fcc1 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 6.7E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02855 6d3b0fb7589cf6bc0cee49395d22fcc1 333 SUPERFAMILY SSF53850 122 288 1.15E-7 T 06-07-2017 CAL12_RS02855 6d3b0fb7589cf6bc0cee49395d22fcc1 333 PIRSF PIRSF017082 1 333 7.3E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23510 82dc29ef3b7f722f87ec8a3919b5855b 224 Gene3D G3DSA:3.30.1130.10 92 221 1.9E-34 T 06-07-2017 CAL12_RS23510 82dc29ef3b7f722f87ec8a3919b5855b 224 SUPERFAMILY SSF55620 5 221 1.63E-55 T 06-07-2017 CAL12_RS23510 82dc29ef3b7f722f87ec8a3919b5855b 224 Gene3D G3DSA:1.10.286.10 37 83 8.6E-12 T 06-07-2017 CAL12_RS23510 82dc29ef3b7f722f87ec8a3919b5855b 224 Pfam PF01227 GTP cyclohydrolase I 43 220 4.1E-45 T 06-07-2017 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 CAL12_RS03340 7d323130a0df449a4c0e15f52765213c 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 45 311 5.0E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 474 491 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 141 160 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 52 77 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 269 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 397 415 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 450 465 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 141 1.6E-29 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 SUPERFAMILY SSF56235 16 588 1.5E-126 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS06140 dbbfd3175c01f267802b2f4a58eb16fa 588 Pfam PF01019 Gamma-glutamyltranspeptidase 45 582 2.5E-109 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS11770 c342a23a98e083203bdb43fca34bc346 192 SUPERFAMILY SSF51182 4 183 7.32E-62 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS11770 c342a23a98e083203bdb43fca34bc346 192 Gene3D G3DSA:2.60.120.10 5 181 2.9E-65 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS11770 c342a23a98e083203bdb43fca34bc346 192 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 10 176 1.3E-53 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAL12_RS11770 c342a23a98e083203bdb43fca34bc346 192 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 172 2.0E-54 T 06-07-2017 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CAL12_RS15810 04165da708242d07c1da4b84593b3bd9 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 267 4.1E-46 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS15810 04165da708242d07c1da4b84593b3bd9 268 Gene3D G3DSA:3.90.226.10 25 207 1.7E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS15810 04165da708242d07c1da4b84593b3bd9 268 SUPERFAMILY SSF52096 20 267 2.31E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS15810 04165da708242d07c1da4b84593b3bd9 268 Gene3D G3DSA:1.10.12.10 211 267 4.8E-17 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS00250 58b2b168614a9097569c50e23a6feab8 330 Pfam PF02625 XdhC and CoxI family 15 81 5.0E-19 T 06-07-2017 IPR003777 XdhC- CoxI CAL12_RS00250 58b2b168614a9097569c50e23a6feab8 330 Pfam PF13478 XdhC Rossmann domain 164 305 8.9E-38 T 06-07-2017 IPR027051 XdhC Rossmann domain CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 7.9E-8 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 06-07-2017 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 Gene3D G3DSA:1.10.10.60 16 70 1.3E-19 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 4.7E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 SUPERFAMILY SSF46689 14 93 3.07E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16755 8e3746d0f22e39aaed602db938063266 202 Gene3D G3DSA:1.10.357.10 71 198 1.3E-18 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 Pfam PF04552 Sigma-54, DNA binding domain 318 473 7.1E-62 T 06-07-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 12 55 1.6E-16 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 363 382 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 454 461 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 PIRSF PIRSF000774 7 476 5.8E-146 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 PRINTS PR00045 Sigma-54 factor signature 375 387 3.6E-27 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 PRINTS PR00045 Sigma-54 factor signature 449 467 3.6E-27 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 PRINTS PR00045 Sigma-54 factor signature 179 196 3.6E-27 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 PRINTS PR00045 Sigma-54 factor signature 391 402 3.6E-27 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 18 473 1.4E-133 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS00660 09e4160508eddfea8db1d343fd255df4 479 Pfam PF04963 Sigma-54 factor, core binding domain 106 303 2.4E-53 T 06-07-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CAL12_RS19300 19a173f8378b6b8d9ea028226ec533ca 483 Pfam PF03972 MmgE/PrpD family 18 466 7.3E-166 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS19300 19a173f8378b6b8d9ea028226ec533ca 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 4.7E-269 T 06-07-2017 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 CAL12_RS19300 19a173f8378b6b8d9ea028226ec533ca 483 SUPERFAMILY SSF103378 12 482 4.45E-167 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS19300 19a173f8378b6b8d9ea028226ec533ca 483 Gene3D G3DSA:3.30.1330.120 287 426 2.2E-65 T 06-07-2017 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-9 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 SUPERFAMILY SSF46785 1 83 7.63E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.8E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 Gene3D G3DSA:3.40.190.10 177 266 1.2E-31 T 06-07-2017 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 SUPERFAMILY SSF53850 88 292 1.16E-37 T 06-07-2017 CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 Gene3D G3DSA:1.10.10.10 1 84 3.7E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 Pfam PF03466 LysR substrate binding domain 87 291 2.1E-42 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS19820 a7b40c47f77c57536301a50a3e0f4b94 308 Gene3D G3DSA:3.40.190.10 89 176 2.0E-24 T 06-07-2017 CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 SMART SM00448 1 112 1.2E-34 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 Gene3D G3DSA:1.10.10.10 126 216 3.0E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 4.9E-21 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 Gene3D G3DSA:3.40.50.2300 2 121 1.3E-34 T 06-07-2017 CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 SUPERFAMILY SSF52172 1 178 3.95E-35 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 SMART SM00862 145 216 5.3E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS26280 fabf800e242412d1de687f95cdfcae05 221 Pfam PF00072 Response regulator receiver domain 3 112 9.2E-24 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS15205 607baf7ee240ad873a9327ea03a5752b 177 Pfam PF01989 Protein of unknown function DUF126 50 133 2.1E-26 T 06-07-2017 IPR002840 Domain of unknown function DUF126 CAL12_RS15205 607baf7ee240ad873a9327ea03a5752b 177 Gene3D G3DSA:3.50.30.10 30 164 5.9E-39 T 06-07-2017 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CAL12_RS15205 607baf7ee240ad873a9327ea03a5752b 177 SUPERFAMILY SSF52016 31 162 1.02E-32 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 Gene3D G3DSA:3.30.870.10 316 465 2.1E-31 T 06-07-2017 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 Gene3D G3DSA:3.30.870.10 113 315 1.2E-43 T 06-07-2017 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 Pfam PF13091 PLD-like domain 331 452 3.9E-23 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 Pfam PF13091 PLD-like domain 136 280 5.6E-15 T 06-07-2017 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 SUPERFAMILY SSF56024 102 320 2.26E-46 T 06-07-2017 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 SUPERFAMILY SSF56024 273 474 2.24E-43 T 06-07-2017 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 SMART SM00155 220 247 33.0 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS07060 a613454474696dc1a6a71f7fab21e15b 488 SMART SM00155 401 428 0.0022 T 06-07-2017 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CAL12_RS11380 f177cb7c92f45200a4b57b39b957cde5 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 131 5.1E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 SMART SM00346 29 120 7.9E-14 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 Gene3D G3DSA:1.10.10.10 23 97 1.3E-17 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 SUPERFAMILY SSF55781 95 274 3.01E-36 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 SUPERFAMILY SSF46785 30 102 6.93E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 Pfam PF09339 IclR helix-turn-helix domain 31 82 1.3E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 Pfam PF01614 Bacterial transcriptional regulator 153 265 6.2E-12 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS06260 ce4440eb0945650477b40659ef176418 276 Gene3D G3DSA:3.30.450.40 98 274 2.2E-35 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS12410 90698ff4a44027188e40e2e7407564f5 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 1.8E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12410 90698ff4a44027188e40e2e7407564f5 330 SUPERFAMILY SSF53850 115 291 3.55E-16 T 06-07-2017 CAL12_RS12410 90698ff4a44027188e40e2e7407564f5 330 PIRSF PIRSF017082 1 329 3.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26955 c4a7bb3e328ad34a9cc8d51b9d5d7bbf 366 PIRSF PIRSF000390 5 366 1.6E-93 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAL12_RS26955 c4a7bb3e328ad34a9cc8d51b9d5d7bbf 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 363 4.9E-100 T 06-07-2017 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CAL12_RS26955 c4a7bb3e328ad34a9cc8d51b9d5d7bbf 366 Gene3D G3DSA:3.40.640.10 15 248 1.3E-64 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS26955 c4a7bb3e328ad34a9cc8d51b9d5d7bbf 366 Gene3D G3DSA:3.90.1150.10 250 365 5.9E-33 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS26955 c4a7bb3e328ad34a9cc8d51b9d5d7bbf 366 SUPERFAMILY SSF53383 16 365 3.14E-90 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 PRINTS PR01438 Universal stress protein signature 108 120 1.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 PRINTS PR01438 Universal stress protein signature 126 148 1.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-18 T 06-07-2017 IPR006015 Universal stress protein A CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 Gene3D G3DSA:3.40.50.620 1 148 1.7E-36 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 Pfam PF00582 Universal stress protein family 1 148 5.9E-30 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS23980 172d9aa1b814f6e4f8e6bb6877b8376d 154 SUPERFAMILY SSF52402 1 148 1.81E-35 T 06-07-2017 CAL12_RS23015 0665cedbecec3cbbbb05853e490f5857 411 Gene3D G3DSA:3.90.550.10 1 226 2.9E-30 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS23015 0665cedbecec3cbbbb05853e490f5857 411 SUPERFAMILY SSF53448 1 223 3.38E-37 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS23015 0665cedbecec3cbbbb05853e490f5857 411 Pfam PF00535 Glycosyl transferase family 2 2 159 8.3E-20 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS13475 bfa9ce706a8689685b0d32eae012e4fc 555 Pfam PF02470 MlaD protein 300 408 1.3E-12 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS13475 bfa9ce706a8689685b0d32eae012e4fc 555 Pfam PF02470 MlaD protein 169 242 1.3E-6 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS13475 bfa9ce706a8689685b0d32eae012e4fc 555 Pfam PF02470 MlaD protein 52 141 1.0E-8 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS19005 70cd19c2499066140a284626f74ce728 172 Gene3D G3DSA:1.20.120.450 4 163 1.9E-22 T 06-07-2017 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase CAL12_RS19005 70cd19c2499066140a284626f74ce728 172 Pfam PF05163 DinB family 1 163 2.1E-29 T 06-07-2017 IPR007837 DNA damage-inducible protein DinB CAL12_RS19005 70cd19c2499066140a284626f74ce728 172 SUPERFAMILY SSF109854 7 143 1.25E-27 T 06-07-2017 CAL12_RS09630 18e2183fa0f6dd9de1fe1cef7d1c6429 492 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 6 462 5.7E-134 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 CAL12_RS09630 18e2183fa0f6dd9de1fe1cef7d1c6429 492 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 4 478 42.692 T 06-07-2017 IPR003846 Uncharacterised protein family UPF0061 CAL12_RS19515 b4712ba574830fed40212198586cb16f 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 330 4.1E-20 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 SMART SM00922 194 290 1.1E-10 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 SUPERFAMILY SSF54826 52 182 3.69E-24 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 Pfam PF13378 Enolase C-terminal domain-like 196 407 9.2E-39 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 Gene3D G3DSA:3.30.390.10 47 183 1.7E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 SUPERFAMILY SSF51604 167 412 2.69E-47 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 Gene3D G3DSA:3.20.20.120 184 412 1.5E-47 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS00125 6515ad30b8d3dc8730f39ac5b25c5665 421 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 53 179 1.7E-14 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS10450 9f877ffe16cbbcdadbe088b639c98330 219 SUPERFAMILY SSF52540 2 134 1.1E-6 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04335 2b26417c589ee4bf44827a29d6c2f504 510 Pfam PF03929 PepSY-associated TM region 3 360 1.4E-56 T 06-07-2017 IPR005625 PepSY-associated TM protein CAL12_RS19635 442ea02195924dfe38fab163b55ab75f 140 Pfam PF06803 Protein of unknown function (DUF1232) 34 69 1.6E-13 T 06-07-2017 IPR010652 Protein of unknown function DUF1232 CAL12_RS06845 f11b2ffb136b2afc6fa500d15f70efcf 125 PIRSF PIRSF029720 1 125 2.1E-48 T 06-07-2017 IPR014558 Uncharacterised conserved lipoprotein CAL12_RS06845 f11b2ffb136b2afc6fa500d15f70efcf 125 Pfam PF03640 Secreted repeat of unknown function 28 69 1.9E-15 T 06-07-2017 IPR005297 Lipoprotein repeat CAL12_RS06845 f11b2ffb136b2afc6fa500d15f70efcf 125 Pfam PF03640 Secreted repeat of unknown function 81 124 1.1E-19 T 06-07-2017 IPR005297 Lipoprotein repeat CAL12_RS23195 7849523354d51592d4798d020506ba37 255 SUPERFAMILY SSF52540 3 247 1.3E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23195 7849523354d51592d4798d020506ba37 255 Pfam PF00005 ABC transporter 23 178 4.7E-25 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS23195 7849523354d51592d4798d020506ba37 255 Gene3D G3DSA:3.40.50.300 2 245 1.0E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23195 7849523354d51592d4798d020506ba37 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.2E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS23195 7849523354d51592d4798d020506ba37 255 SMART SM00382 30 225 4.7E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS23195 7849523354d51592d4798d020506ba37 255 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 SUPERFAMILY SSF56954 15 39 9.68E-110 T 06-07-2017 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 SUPERFAMILY SSF56954 75 490 9.68E-110 T 06-07-2017 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 Gene3D G3DSA:1.20.1600.10 73 491 1.7E-116 T 06-07-2017 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 21 489 3.2E-122 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 Pfam PF02321 Outer membrane efflux protein 300 487 2.1E-29 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS14115 8d2b35f5dd8179cc9fcd51753a624a52 492 Pfam PF02321 Outer membrane efflux protein 84 276 5.0E-25 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 SUPERFAMILY SSF53850 89 303 6.7E-36 T 06-07-2017 CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 Pfam PF03466 LysR substrate binding domain 88 299 2.2E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.8E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 Gene3D G3DSA:3.40.190.10 176 268 3.1E-18 T 06-07-2017 CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 SUPERFAMILY SSF46785 2 112 5.92E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 Gene3D G3DSA:1.10.10.10 1 86 1.1E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01185 ef00cfb446c1a2ff09130e08129606d2 319 Gene3D G3DSA:3.40.190.10 92 175 1.1E-18 T 06-07-2017 CAL12_RS01805 83babb03affeb9d3f4800394e1606b3d 259 Pfam PF13847 Methyltransferase domain 32 156 7.0E-17 T 06-07-2017 IPR025714 Methyltransferase domain CAL12_RS01805 83babb03affeb9d3f4800394e1606b3d 259 Gene3D G3DSA:1.10.150.290 184 239 1.8E-24 T 06-07-2017 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS01805 83babb03affeb9d3f4800394e1606b3d 259 SUPERFAMILY SSF53335 17 225 1.43E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS01805 83babb03affeb9d3f4800394e1606b3d 259 Gene3D G3DSA:3.40.50.150 5 179 3.7E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS10715 c97ff95a91476cdb2f2f4a7ada2321a2 494 Pfam PF07171 MlrC C-terminus 304 481 5.5E-48 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS10715 c97ff95a91476cdb2f2f4a7ada2321a2 494 PIRSF PIRSF012702 1 494 1.6E-141 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS10715 c97ff95a91476cdb2f2f4a7ada2321a2 494 Pfam PF07364 Metallopeptidase family M81 4 292 3.1E-80 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS15710 4d8a648154702addc6841e10de2a1c38 283 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 272 1.1E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 SUPERFAMILY SSF50715 1 190 3.31E-52 T 06-07-2017 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Pfam PF01386 Ribosomal L25p family 4 91 5.4E-25 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 94 23.053 T 06-07-2017 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 183 7.1E-25 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 185 29.647 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Gene3D G3DSA:2.170.120.20 98 190 1.7E-24 T 06-07-2017 IPR020057 Ribosomal protein L25, beta domain CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 173 1.0E-41 T 06-07-2017 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 94 2.0E-34 T 06-07-2017 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CAL12_RS02805 1e989e6557f2ed8a4ff653825d1d3548 207 Gene3D G3DSA:2.40.240.10 1 94 1.1E-32 T 06-07-2017 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CAL12_RS25300 05175f5eb1f389a4be58e4ceab4dc3fb 299 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 12 284 9.0E-50 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAL12_RS25300 05175f5eb1f389a4be58e4ceab4dc3fb 299 PIRSF PIRSF038471 10 291 6.9E-69 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAL12_RS25300 05175f5eb1f389a4be58e4ceab4dc3fb 299 Pfam PF04085 rod shape-determining protein MreC 130 276 2.0E-36 T 06-07-2017 IPR007221 Rod shape-determining protein MreC GO:0008360 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 Gene3D G3DSA:3.40.190.80 176 257 1.1E-12 T 06-07-2017 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 Gene3D G3DSA:3.30.540.10 9 170 4.4E-35 T 06-07-2017 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 Pfam PF00459 Inositol monophosphatase family 9 255 1.6E-47 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 5.1E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 5.1E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 5.1E-17 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS08050 712b08a7df9700bcd3ca65b40a39afa2 278 SUPERFAMILY SSF56655 10 273 3.14E-62 T 06-07-2017 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 SMART SM00342 230 313 1.9E-29 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 313 2.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 282 297 2.4E-5 T 06-07-2017 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 Pfam PF12852 Cupin 17 197 9.4E-37 T 06-07-2017 IPR032783 AraC-type transcription regulator, ligand-binding domain CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 267 309 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 SUPERFAMILY SSF46689 213 263 8.51E-8 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 Gene3D G3DSA:1.10.10.60 211 267 1.3E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 215 259 - T 06-07-2017 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 Pfam PF12833 Helix-turn-helix domain 236 314 2.0E-20 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 SUPERFAMILY SSF46689 266 315 4.93E-12 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS13820 fa086db342fee8a74daf47f0ca74205f 323 Gene3D G3DSA:1.10.10.60 268 314 5.1E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20430 abea081c2ee5fac779422e7ffaba0caf 69 Gene3D G3DSA:3.30.420.10 25 65 7.5E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS20430 abea081c2ee5fac779422e7ffaba0caf 69 Pfam PF13683 Integrase core domain 24 64 8.4E-13 T 06-07-2017 IPR001584 Integrase, catalytic core GO:0015074 CAL12_RS20430 abea081c2ee5fac779422e7ffaba0caf 69 SUPERFAMILY SSF53098 25 67 3.98E-5 T 06-07-2017 IPR012337 Ribonuclease H-like domain GO:0003676 CAL12_RS27725 9f9b0e8366e3380e97bb9e50fed1cd9d 379 SUPERFAMILY SSF53383 10 359 6.05E-24 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS27725 9f9b0e8366e3380e97bb9e50fed1cd9d 379 Gene3D G3DSA:3.40.640.10 24 248 1.3E-13 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS05250 abfc3a79cbad077b97acfae12ff842e0 254 Gene3D G3DSA:3.40.50.300 5 245 7.6E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05250 abfc3a79cbad077b97acfae12ff842e0 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 7.9E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS05250 abfc3a79cbad077b97acfae12ff842e0 254 Pfam PF00005 ABC transporter 22 176 2.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05250 abfc3a79cbad077b97acfae12ff842e0 254 SUPERFAMILY SSF52540 6 246 1.23E-55 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05250 abfc3a79cbad077b97acfae12ff842e0 254 SMART SM00382 30 224 0.0021 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24205 b75581bc3eec856c34cf5c4fc1a1e8a9 418 Pfam PF00266 Aminotransferase class-V 13 348 1.0E-27 T 06-07-2017 IPR000192 Aminotransferase class V domain CAL12_RS24205 b75581bc3eec856c34cf5c4fc1a1e8a9 418 PIRSF PIRSF000524 7 406 1.5E-118 T 06-07-2017 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CAL12_RS24205 b75581bc3eec856c34cf5c4fc1a1e8a9 418 Gene3D G3DSA:3.90.1150.10 277 387 6.1E-31 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS24205 b75581bc3eec856c34cf5c4fc1a1e8a9 418 Gene3D G3DSA:3.40.640.10 23 276 2.3E-48 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS24205 b75581bc3eec856c34cf5c4fc1a1e8a9 418 SUPERFAMILY SSF53383 10 385 6.93E-94 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS26970 7cac16135fc03f0aa86241bca4076a52 312 Gene3D G3DSA:3.40.50.720 5 242 6.4E-33 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26970 7cac16135fc03f0aa86241bca4076a52 312 SUPERFAMILY SSF51735 5 261 1.07E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS26970 7cac16135fc03f0aa86241bca4076a52 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 213 1.9E-15 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 Gene3D G3DSA:3.30.540.10 2 149 9.2E-52 T 06-07-2017 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 06-07-2017 IPR020583 Inositol monophosphatase, metal-binding site CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 06-07-2017 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 Pfam PF00459 Inositol monophosphatase family 2 250 1.4E-60 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 Gene3D G3DSA:3.40.190.80 150 256 1.2E-29 T 06-07-2017 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 SUPERFAMILY SSF56655 1 256 7.07E-81 T 06-07-2017 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 1.6E-57 T 06-07-2017 IPR000760 Inositol monophosphatase GO:0046854 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 8.5E-14 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 8.5E-14 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS07580 b28ada92c27de2528c23a6589d26f3b3 258 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 8.5E-14 T 06-07-2017 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 Gene3D G3DSA:3.90.1150.10 275 371 3.6E-22 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 370 2.2E-105 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 SUPERFAMILY SSF53383 19 371 2.78E-83 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 Pfam PF00155 Aminotransferase class I and II 40 364 1.4E-52 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 Gene3D G3DSA:3.40.640.10 53 274 3.3E-67 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS18940 76ab3f33943e7a4b89b0ab91718c7b42 374 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 371 61.141 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS11445 4f376ad9349fdaebe33bd872871752f6 308 Gene3D G3DSA:3.40.50.1820 5 292 4.0E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11445 4f376ad9349fdaebe33bd872871752f6 308 SUPERFAMILY SSF53474 7 292 4.59E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11445 4f376ad9349fdaebe33bd872871752f6 308 Pfam PF00561 alpha/beta hydrolase fold 24 278 6.9E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 123 37.208 T 06-07-2017 IPR023063 FeS cluster insertion protein ErpA GO:0016226 CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 Gene3D G3DSA:2.60.300.12 18 112 3.6E-32 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 SUPERFAMILY SSF89360 18 112 7.65E-31 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 19 123 1.2E-38 T 06-07-2017 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 104 121 - T 06-07-2017 IPR017870 FeS cluster insertion, C-terminal, conserved site CAL12_RS24730 a156d20fe896c68af38a5f414c305983 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 118 2.5E-20 T 06-07-2017 IPR000361 FeS cluster biogenesis CAL12_RS27880 2650f2e9e7c39cb7729b625653720dc3 438 Pfam PF01554 MatE 244 394 2.7E-20 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS27880 2650f2e9e7c39cb7729b625653720dc3 438 Pfam PF01554 MatE 16 176 1.9E-23 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS27880 2650f2e9e7c39cb7729b625653720dc3 438 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 391 1.9E-45 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS27880 2650f2e9e7c39cb7729b625653720dc3 438 PIRSF PIRSF006603 1 438 4.3E-68 T 06-07-2017 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CAL12_RS07795 2321d758e0cc950dc12cb5c88a01ef59 239 Gene3D G3DSA:3.40.50.300 8 225 6.7E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07795 2321d758e0cc950dc12cb5c88a01ef59 239 SMART SM00382 34 216 2.5E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07795 2321d758e0cc950dc12cb5c88a01ef59 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07795 2321d758e0cc950dc12cb5c88a01ef59 239 SUPERFAMILY SSF52540 9 225 4.69E-54 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07795 2321d758e0cc950dc12cb5c88a01ef59 239 Pfam PF00005 ABC transporter 25 167 2.4E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS09850 c8fa1b427fc96e70154f6e19b1f7737c 382 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 10 366 2.1E-105 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS09850 c8fa1b427fc96e70154f6e19b1f7737c 382 PIRSF PIRSF000267 5 379 2.0E-115 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS09850 c8fa1b427fc96e70154f6e19b1f7737c 382 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 378 2.3E-138 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 23 316 5.4E-17 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 SUPERFAMILY SSF52283 1 134 3.19E-21 T 06-07-2017 CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 1.1E-45 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 Gene3D G3DSA:3.40.50.720 1 111 8.6E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 SUPERFAMILY SSF51735 104 285 7.15E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18205 3913113f7e37740f7f2d4bea32070efa 324 Gene3D G3DSA:3.40.50.720 112 286 4.1E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20500 587a53e8218d854aa41e87af54692ed7 85 Pfam PF06906 Protein of unknown function (DUF1272) 1 57 2.5E-26 T 06-07-2017 IPR010696 Protein of unknown function DUF1272 CAL12_RS01035 3172e33e57153c794ec11867e57467f6 202 SUPERFAMILY SSF52833 46 201 7.49E-53 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS01035 3172e33e57153c794ec11867e57467f6 202 Gene3D G3DSA:3.40.30.10 21 201 5.3E-62 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS01035 3172e33e57153c794ec11867e57467f6 202 Pfam PF02630 SCO1/SenC 42 179 9.8E-47 T 06-07-2017 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 SUPERFAMILY SSF46785 5 86 1.24E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 SUPERFAMILY SSF53850 90 293 6.41E-35 T 06-07-2017 CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 Gene3D G3DSA:3.40.190.10 93 175 6.3E-16 T 06-07-2017 CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 Pfam PF03466 LysR substrate binding domain 90 292 1.4E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 Gene3D G3DSA:1.10.10.10 5 86 2.3E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23295 48bdb262bca5ae2ff9b07c8beca85c09 298 Gene3D G3DSA:3.40.190.10 176 262 1.5E-17 T 06-07-2017 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 SUPERFAMILY SSF69287 3 77 3.27E-17 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 Gene3D G3DSA:3.30.70.790 79 149 2.2E-29 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 SUPERFAMILY SSF69737 77 144 1.03E-19 T 06-07-2017 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 145 24.528 T 06-07-2017 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 SMART SM00988 7 71 3.6E-22 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 Gene3D G3DSA:2.60.260.20 22 77 7.1E-19 T 06-07-2017 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 PRINTS PR00334 HMW kininogen signature 201 224 1.7E-11 T 06-07-2017 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-416476|Reactome: R-HSA-418594 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 PRINTS PR00334 HMW kininogen signature 235 250 1.7E-11 T 06-07-2017 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-416476|Reactome: R-HSA-418594 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 PRINTS PR00334 HMW kininogen signature 176 197 1.7E-11 T 06-07-2017 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-416476|Reactome: R-HSA-418594 CAL12_RS18390 845d79d51b85cf6ca18d76db8d7abbc2 250 Pfam PF02814 UreE urease accessory protein, N-terminal domain 15 71 1.2E-20 T 06-07-2017 IPR004029 UreE urease accessory, N-terminal CAL12_RS02530 9feb14bdb3645e92a1ecc0a09a3e371b 297 Pfam PF10547 P22_AR N-terminal domain 50 145 6.6E-8 T 06-07-2017 IPR018875 Antirepressor protein ANT, N-terminal CAL12_RS25910 e295eeb19255e385c8799b4661c9b63d 554 Pfam PF02538 Hydantoinase B/oxoprolinase 17 523 4.1E-166 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 ProSitePatterns PS00768 Transthyretin signature 1. 185 200 - T 06-07-2017 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 SUPERFAMILY SSF49472 176 294 2.88E-36 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 Gene3D G3DSA:2.60.40.180 180 294 6.4E-33 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 Gene3D G3DSA:1.10.3330.10 14 170 1.0E-46 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 SUPERFAMILY SSF158694 6 168 2.09E-45 T 06-07-2017 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 PRINTS PR00189 Transthyretin signature 272 294 5.6E-5 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 PRINTS PR00189 Transthyretin signature 181 201 5.6E-5 T 06-07-2017 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 181 294 6.1E-34 T 06-07-2017 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 15 167 4.6E-48 T 06-07-2017 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 Pfam PF09349 OHCU decarboxylase 11 167 9.1E-39 T 06-07-2017 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394 CAL12_RS03205 c9c970fef1785e14c8e3243a71dc4fc4 294 Pfam PF00576 HIUase/Transthyretin family 182 293 3.5E-31 T 06-07-2017 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CAL12_RS22085 1b2c17a8eb100e47ae63e134bb4769c4 232 Pfam PF06578 YOP proteins translocation protein K (YscK) 49 180 8.6E-7 T 06-07-2017 IPR009510 Type III secretion system, secretion protein K GO:0009405 CAL12_RS20980 dc539fa4206514b42ed7660642a53853 520 Pfam PF02538 Hydantoinase B/oxoprolinase 15 519 3.3E-130 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS11440 ddb6e4f9b005158e2bb126403ade56b5 288 Pfam PF05368 NmrA-like family 3 224 1.6E-20 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAL12_RS11440 ddb6e4f9b005158e2bb126403ade56b5 288 SUPERFAMILY SSF51735 3 242 7.3E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11440 ddb6e4f9b005158e2bb126403ade56b5 288 Gene3D G3DSA:3.40.50.720 2 224 4.6E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11875 43097ef620082c769dfc53f3a16545b6 155 SUPERFAMILY SSF140566 3 128 3.14E-21 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CAL12_RS11875 43097ef620082c769dfc53f3a16545b6 155 Pfam PF05130 FlgN protein 1 144 6.7E-28 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CAL12_RS11875 43097ef620082c769dfc53f3a16545b6 155 Gene3D G3DSA:1.20.58.300 4 128 7.1E-24 T 06-07-2017 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CAL12_RS06750 11e0e1b9b7674cc63e2694325c50634c 290 Gene3D G3DSA:3.20.20.60 2 288 1.5E-83 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06750 11e0e1b9b7674cc63e2694325c50634c 290 SUPERFAMILY SSF51621 3 288 3.59E-85 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06750 11e0e1b9b7674cc63e2694325c50634c 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 252 4.8E-48 T 06-07-2017 CAL12_RS21090 923714cd40fc706d770f431b4ade0aa2 105 SUPERFAMILY SSF103481 12 104 4.97E-7 T 06-07-2017 CAL12_RS21090 923714cd40fc706d770f431b4ade0aa2 105 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 2 105 1.6E-36 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAL12_RS21090 923714cd40fc706d770f431b4ade0aa2 105 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 105 24.633 T 06-07-2017 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 CAL12_RS15130 f82b92ebcb48a26a80bd95c9587cb11d 348 Pfam PF13416 Bacterial extracellular solute-binding protein 46 307 6.8E-32 T 06-07-2017 CAL12_RS15130 f82b92ebcb48a26a80bd95c9587cb11d 348 SUPERFAMILY SSF53850 31 344 2.26E-57 T 06-07-2017 CAL12_RS15130 f82b92ebcb48a26a80bd95c9587cb11d 348 Gene3D G3DSA:3.40.190.10 135 271 2.5E-31 T 06-07-2017 CAL12_RS15130 f82b92ebcb48a26a80bd95c9587cb11d 348 Gene3D G3DSA:3.40.190.10 272 309 9.2E-23 T 06-07-2017 CAL12_RS15130 f82b92ebcb48a26a80bd95c9587cb11d 348 Gene3D G3DSA:3.40.190.10 36 134 9.2E-23 T 06-07-2017 CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 SMART SM00345 26 85 1.6E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 Pfam PF07702 UTRA domain 114 244 4.4E-9 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 SUPERFAMILY SSF46785 18 89 1.08E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 SUPERFAMILY SSF64288 73 249 1.05E-19 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 Gene3D G3DSA:3.40.1410.10 81 246 1.2E-16 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 Gene3D G3DSA:1.10.10.10 20 80 3.0E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04070 782e320e0e3d0298a0389de2fe4a4266 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 85 1.1E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 380 404 - T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 Pfam PF01019 Gamma-glutamyltranspeptidase 54 549 4.2E-176 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 SUPERFAMILY SSF56235 30 585 8.88E-178 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 39 545 2.3E-166 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 469 486 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 251 267 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 281 300 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 398 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 445 460 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 61 86 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 152 171 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 134 152 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12450 a181033f39b66ee5c9e3f03bc358d985 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 422 9.6E-75 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS03375 a67c91dada0d032282bc34e65249a6b2 312 Pfam PF01522 Polysaccharide deacetylase 74 172 8.8E-11 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS03375 a67c91dada0d032282bc34e65249a6b2 312 SUPERFAMILY SSF88713 7 305 4.73E-74 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS03375 a67c91dada0d032282bc34e65249a6b2 312 Gene3D G3DSA:3.20.20.370 7 305 1.2E-85 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 175 514 9.7E-96 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 Pfam PF02321 Outer membrane efflux protein 332 512 2.0E-30 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 Pfam PF02321 Outer membrane efflux protein 75 302 4.0E-36 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 Gene3D G3DSA:1.20.1600.10 64 134 1.6E-121 T 06-07-2017 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 Gene3D G3DSA:1.20.1600.10 173 517 1.6E-121 T 06-07-2017 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 SUPERFAMILY SSF56954 66 126 8.89E-120 T 06-07-2017 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 SUPERFAMILY SSF56954 1 34 8.89E-120 T 06-07-2017 CAL12_RS04260 8375ce0d986fc57fe43994d9bcd78269 523 SUPERFAMILY SSF56954 165 517 8.89E-120 T 06-07-2017 CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:3.40.50.300 185 282 7.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:3.40.50.300 7 110 7.5E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 268 2.5E-66 T 06-07-2017 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:1.10.486.10 386 547 6.8E-35 T 06-07-2017 CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:3.40.50.300 559 654 4.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:3.40.50.300 283 385 4.2E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 7 684 37.666 T 06-07-2017 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Pfam PF13361 UvrD-like helicase C-terminal domain 274 634 4.6E-60 T 06-07-2017 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 Gene3D G3DSA:1.10.10.160 114 184 1.2E-14 T 06-07-2017 IPR013986 DExx box DNA helicase domain CAL12_RS25765 44040ea60b11c0dec038acbf7af82673 688 SUPERFAMILY SSF52540 5 654 4.97E-152 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 SUPERFAMILY SSF52540 230 435 2.12E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 Gene3D G3DSA:1.20.120.140 160 241 2.0E-28 T 06-07-2017 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 Gene3D G3DSA:3.40.50.300 242 435 5.3E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 Pfam PF02881 SRP54-type protein, helical bundle domain 151 212 3.7E-10 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 159 432 1.9E-95 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 SMART SM00382 229 379 9.8E-7 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 Pfam PF00448 SRP54-type protein, GTPase domain 231 433 2.0E-65 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 SUPERFAMILY SSF47364 135 209 2.62E-18 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 SMART SM00962 230 434 8.7E-104 T 06-07-2017 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 159 434 56.961 T 06-07-2017 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CAL12_RS02950 bf6352210295e22914da39bfb30b2b21 437 SMART SM00963 140 216 8.9E-17 T 06-07-2017 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CAL12_RS18255 91d776a11861565ae5ba4867b95638b5 332 PIRSF PIRSF026166 1 328 2.2E-132 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter CAL12_RS18255 91d776a11861565ae5ba4867b95638b5 332 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 10 319 1.7E-97 T 06-07-2017 IPR016833 Putative sodium bile acid cotransporter CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 SUPERFAMILY SSF46785 2 83 1.6E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 Pfam PF03466 LysR substrate binding domain 91 297 9.6E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 7.6E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 SUPERFAMILY SSF53850 93 300 3.84E-44 T 06-07-2017 CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 Gene3D G3DSA:3.40.190.10 179 263 2.9E-20 T 06-07-2017 CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 Gene3D G3DSA:3.40.190.10 93 178 2.8E-19 T 06-07-2017 CAL12_RS27585 685a1e9e9d858494f11a9e91187a49be 306 Gene3D G3DSA:1.10.10.10 4 88 1.4E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25470 64db3eef5bb75e83db5ec8429ca36277 278 Gene3D G3DSA:1.10.260.40 19 94 3.9E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25470 64db3eef5bb75e83db5ec8429ca36277 278 Pfam PF13560 Helix-turn-helix domain 23 100 9.9E-17 T 06-07-2017 CAL12_RS25470 64db3eef5bb75e83db5ec8429ca36277 278 SUPERFAMILY SSF47413 46 94 8.0E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS25470 64db3eef5bb75e83db5ec8429ca36277 278 SMART SM00530 26 98 1.4E-4 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 Pfam PF03797 Autotransporter beta-domain 675 936 1.5E-54 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 339 371 2.0E-5 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 Gene3D G3DSA:2.40.128.130 673 952 1.4E-61 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 SMART SM00869 675 942 3.5E-48 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 SUPERFAMILY SSF103515 619 952 3.4E-62 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 SUPERFAMILY SSF51126 107 487 1.32E-16 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS05910 d0bac0f69f951547b2dc53a3e1cc408f 952 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 409 949 2.9E-41 T 06-07-2017 IPR006315 Outer membrane autotransporter barrel GO:0019867 CAL12_RS10205 d469612e6055de1829e4c73e34e0df0b 267 Pfam PF01553 Acyltransferase 93 199 1.0E-12 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS10205 d469612e6055de1829e4c73e34e0df0b 267 SUPERFAMILY SSF69593 35 238 3.27E-25 T 06-07-2017 CAL12_RS10205 d469612e6055de1829e4c73e34e0df0b 267 Gene3D G3DSA:3.40.1130.10 93 242 1.2E-7 T 06-07-2017 CAL12_RS10205 d469612e6055de1829e4c73e34e0df0b 267 SMART SM00563 93 201 1.1E-18 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS26890 ea962447b270613a86f2719b8da77c15 311 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 60 299 5.8E-67 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS26890 ea962447b270613a86f2719b8da77c15 311 SUPERFAMILY SSF53756 2 310 5.57E-58 T 06-07-2017 CAL12_RS26890 ea962447b270613a86f2719b8da77c15 311 Gene3D G3DSA:3.40.50.2000 2 131 9.1E-25 T 06-07-2017 CAL12_RS26890 ea962447b270613a86f2719b8da77c15 311 Gene3D G3DSA:3.40.50.2000 166 286 1.5E-28 T 06-07-2017 CAL12_RS26890 ea962447b270613a86f2719b8da77c15 311 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 1 309 1.0E-107 T 06-07-2017 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 Pfam PF01928 CYTH domain 1 185 1.5E-20 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 SMART SM00880 237 583 7.3E-55 T 06-07-2017 IPR007899 CHAD domain CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 Gene3D G3DSA:2.40.320.10 2 192 1.0E-21 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 SUPERFAMILY SSF55154 1 192 7.85E-33 T 06-07-2017 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 Pfam PF05235 CHAD domain 240 548 1.1E-41 T 06-07-2017 IPR007899 CHAD domain CAL12_RS02955 2deadd2d95fe494b97f1ad0ab3490fd9 591 SMART SM01118 1 193 5.2E-26 T 06-07-2017 IPR023577 CYTH domain Reactome: R-HSA-196819 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 5.5E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 5.5E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 5.5E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 5.5E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 5.5E-23 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 PIRSF PIRSF000349 1 192 2.5E-87 T 06-07-2017 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 06-07-2017 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 1.5E-35 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 2.3E-41 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 Gene3D G3DSA:1.10.287.990 20 82 2.8E-25 T 06-07-2017 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 SUPERFAMILY SSF54719 85 191 2.75E-44 T 06-07-2017 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS17425 03b475aa55c3b81c1e50d15e4cd8987b 192 SUPERFAMILY SSF46609 1 84 6.02E-36 T 06-07-2017 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 Gene3D G3DSA:1.10.10.10 27 94 1.5E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 SMART SM00345 34 93 1.1E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 93 5.2E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 Gene3D G3DSA:3.90.1150.10 381 463 3.3E-5 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 Pfam PF00155 Aminotransferase class I and II 161 473 1.1E-29 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 SUPERFAMILY SSF53383 123 480 1.05E-69 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 SUPERFAMILY SSF46785 26 97 3.13E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03570 47ae13fea1c3efc35560d9ab5c9141d3 484 Gene3D G3DSA:3.40.640.10 160 379 1.6E-55 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS21890 e0268b73f24a6b936bda80d4b92629a1 148 SUPERFAMILY SSF55729 11 131 1.11E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS21890 e0268b73f24a6b936bda80d4b92629a1 148 Pfam PF00583 Acetyltransferase (GNAT) family 54 131 1.9E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS21890 e0268b73f24a6b936bda80d4b92629a1 148 Gene3D G3DSA:3.40.630.30 11 142 1.3E-21 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS22000 95ca9bad78dce837a154a3f1ef1a750e 649 SUPERFAMILY SSF53649 270 596 8.51E-65 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS22000 95ca9bad78dce837a154a3f1ef1a750e 649 Pfam PF00884 Sulfatase 272 538 1.8E-40 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS22000 95ca9bad78dce837a154a3f1ef1a750e 649 Gene3D G3DSA:3.40.720.10 272 555 1.0E-39 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS02345 4d8422a64c7fbe2a449e93e6a62dfe5e 121 Pfam PF13663 Domain of unknown function (DUF4148) 15 82 2.0E-10 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS04355 4ca3e083fe9c4a4a8b8f25f5753bb418 196 Gene3D G3DSA:2.60.120.10 59 163 5.1E-16 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS04355 4ca3e083fe9c4a4a8b8f25f5753bb418 196 PIRSF PIRSF019307 28 195 1.4E-62 T 06-07-2017 IPR014500 Uncharacterised conserved protein UCP019307, cupin-type CAL12_RS04355 4ca3e083fe9c4a4a8b8f25f5753bb418 196 Pfam PF00190 Cupin 91 148 7.0E-5 T 06-07-2017 IPR006045 Cupin 1 GO:0045735 CAL12_RS04355 4ca3e083fe9c4a4a8b8f25f5753bb418 196 SUPERFAMILY SSF51182 67 160 3.66E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS23270 3f324a00e51c4c2538db841688580798 309 Pfam PF04909 Amidohydrolase 20 299 4.5E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS23270 3f324a00e51c4c2538db841688580798 309 SUPERFAMILY SSF51556 18 300 1.92E-45 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23270 3f324a00e51c4c2538db841688580798 309 Gene3D G3DSA:3.20.20.140 18 302 1.1E-53 T 06-07-2017 CAL12_RS01495 08c8d94dd3adfaf356c90d04dad50d5f 108 SUPERFAMILY SSF50118 2 106 5.89E-22 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CAL12_RS01495 08c8d94dd3adfaf356c90d04dad50d5f 108 Gene3D G3DSA:2.30.30.110 18 106 5.1E-12 T 06-07-2017 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CAL12_RS01495 08c8d94dd3adfaf356c90d04dad50d5f 108 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 2.2E-17 T 06-07-2017 IPR003477 mRNA interferase PemK-like protein GO:0003677 CAL12_RS22685 0717e7320f79c69170ecfa87e7dc3268 129 Pfam PF14107 Domain of unknown function (DUF4280) 5 122 5.3E-25 T 06-07-2017 IPR025460 Protein of unknown function DUF4280 CAL12_RS20480 7ec720b36750e336c0f6f00deebc47f8 130 Pfam PF01042 Endoribonuclease L-PSP 23 130 1.7E-26 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS20480 7ec720b36750e336c0f6f00deebc47f8 130 SUPERFAMILY SSF55298 19 130 4.71E-33 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS20480 7ec720b36750e336c0f6f00deebc47f8 130 Gene3D G3DSA:3.30.1330.40 20 129 8.7E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS12945 eb568794d38bc8357960e813f828f9be 273 SUPERFAMILY SSF52218 1 257 1.1E-67 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS12945 eb568794d38bc8357960e813f828f9be 273 Pfam PF02525 Flavodoxin-like fold 1 211 7.9E-55 T 06-07-2017 IPR003680 Flavodoxin-like fold CAL12_RS12945 eb568794d38bc8357960e813f828f9be 273 Gene3D G3DSA:3.40.50.360 1 234 3.2E-69 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS12660 bd95916a3e1e357bd88eb08e95450a63 150 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 52 113 7.6E-13 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12660 bd95916a3e1e357bd88eb08e95450a63 150 Gene3D G3DSA:1.10.10.10 30 142 7.5E-38 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12660 bd95916a3e1e357bd88eb08e95450a63 150 SUPERFAMILY SSF46785 32 139 1.9E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 554 1.2E-64 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 Pfam PF02203 Tar ligand binding domain homologue 33 208 3.0E-16 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 SMART SM00304 255 307 1.7E-12 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 SUPERFAMILY SSF58104 275 556 9.16E-79 T 06-07-2017 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 SUPERFAMILY SSF47170 55 214 4.71E-6 T 06-07-2017 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 Gene3D G3DSA:1.10.287.950 323 527 8.5E-65 T 06-07-2017 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 Pfam PF00672 HAMP domain 237 303 5.1E-13 T 06-07-2017 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 SMART SM00283 308 555 5.8E-98 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 33 58 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 435 464 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 88 103 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 483 512 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 329 358 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS11955 b662dc62e9d406a3626c91e471922f2d 581 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 433 2.9E-68 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 Gene3D G3DSA:3.40.50.720 5 109 6.7E-28 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 Gene3D G3DSA:3.40.50.720 110 287 2.2E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 285 1.1E-55 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 44 313 1.9E-23 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 SUPERFAMILY SSF51735 104 286 2.59E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 SUPERFAMILY SSF52283 2 135 2.27E-28 T 06-07-2017 CAL12_RS18815 b6c7a6251a2f92a08e18d11783ad5768 331 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 06-07-2017 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Gene3D G3DSA:2.40.110.10 122 216 1.4E-27 T 06-07-2017 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.8E-23 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 SUPERFAMILY SSF47203 225 375 1.77E-42 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 213 4.3E-18 T 06-07-2017 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 SUPERFAMILY SSF56645 1 225 1.57E-56 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 372 7.9E-40 T 06-07-2017 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Gene3D G3DSA:1.10.540.10 1 119 1.3E-28 T 06-07-2017 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 CAL12_RS27950 cf0da2fc238643e8e3af41d2768e68c1 385 Gene3D G3DSA:1.20.140.10 217 375 2.9E-49 T 06-07-2017 CAL12_RS13600 c8a6ae9d1103be8cafc686a0055981a8 381 Gene3D G3DSA:3.10.310.10 180 360 3.4E-59 T 06-07-2017 CAL12_RS13600 c8a6ae9d1103be8cafc686a0055981a8 381 Pfam PF04303 PrpF protein 4 378 6.5E-113 T 06-07-2017 IPR007400 PrpF protein CAL12_RS13600 c8a6ae9d1103be8cafc686a0055981a8 381 SUPERFAMILY SSF54506 1 170 9.42E-63 T 06-07-2017 CAL12_RS13600 c8a6ae9d1103be8cafc686a0055981a8 381 SUPERFAMILY SSF54506 175 379 3.3E-58 T 06-07-2017 CAL12_RS13600 c8a6ae9d1103be8cafc686a0055981a8 381 Gene3D G3DSA:3.10.310.10 1 179 1.8E-78 T 06-07-2017 CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 Pfam PF00462 Glutaredoxin 4 64 3.7E-18 T 06-07-2017 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 Gene3D G3DSA:3.40.30.10 1 79 3.7E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 06-07-2017 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 PRINTS PR00160 Glutaredoxin signature 47 60 6.8E-16 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 PRINTS PR00160 Glutaredoxin signature 61 74 6.8E-16 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 PRINTS PR00160 Glutaredoxin signature 4 22 6.8E-16 T 06-07-2017 IPR014025 Glutaredoxin subgroup CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 5.6E-33 T 06-07-2017 IPR011900 Glutaredoxin, GrxC GO:0045454 CAL12_RS26200 d45f22228d56eb610da1523b3659926d 84 SUPERFAMILY SSF52833 1 83 1.19E-25 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS06250 7050dd3637de2379b3d65d0f5adc9e04 326 SUPERFAMILY SSF53850 92 289 5.02E-15 T 06-07-2017 CAL12_RS06250 7050dd3637de2379b3d65d0f5adc9e04 326 Gene3D G3DSA:3.40.190.10 128 248 2.9E-4 T 06-07-2017 CAL12_RS06250 7050dd3637de2379b3d65d0f5adc9e04 326 PIRSF PIRSF017082 1 325 7.4E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06250 7050dd3637de2379b3d65d0f5adc9e04 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 7.2E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07290 51d591b7d744947b548f78b8e99b2c9a 241 Gene3D G3DSA:3.40.50.360 31 209 6.0E-17 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS07290 51d591b7d744947b548f78b8e99b2c9a 241 Pfam PF03358 NADPH-dependent FMN reductase 32 176 9.0E-12 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAL12_RS07290 51d591b7d744947b548f78b8e99b2c9a 241 SUPERFAMILY SSF52218 32 204 2.99E-16 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS23710 2e5ee5075f6b8cc0e51753cc132be24e 445 SUPERFAMILY SSF51556 118 442 4.54E-46 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23710 2e5ee5075f6b8cc0e51753cc132be24e 445 Gene3D G3DSA:3.20.20.140 153 442 5.7E-54 T 06-07-2017 CAL12_RS23710 2e5ee5075f6b8cc0e51753cc132be24e 445 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 152 441 6.6E-46 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CAL12_RS07090 c37cb31f2d4a0bddae708bdaa6246a5c 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 13 278 1.0E-6 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07090 c37cb31f2d4a0bddae708bdaa6246a5c 288 Gene3D G3DSA:1.10.3720.10 9 278 2.9E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07090 c37cb31f2d4a0bddae708bdaa6246a5c 288 SUPERFAMILY SSF161098 7 278 4.97E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 SMART SM00345 33 91 2.4E-16 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 91 1.2E-14 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 SUPERFAMILY SSF48008 97 231 1.54E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 Pfam PF07729 FCD domain 101 224 8.2E-27 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 Gene3D G3DSA:1.10.10.10 22 93 7.7E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 SUPERFAMILY SSF46785 24 95 1.94E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 Gene3D G3DSA:1.20.120.530 94 232 1.3E-30 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS18540 1bbc5e77f6053e99f5a3e3f21af53fee 234 SMART SM00895 101 225 9.8E-19 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS03885 31c8d32f336fc325000f7ce4e720a518 293 Gene3D G3DSA:3.90.850.10 64 283 1.7E-73 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03885 31c8d32f336fc325000f7ce4e720a518 293 SUPERFAMILY SSF56529 61 281 1.28E-72 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03885 31c8d32f336fc325000f7ce4e720a518 293 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 281 6.2E-61 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS10095 d579b381a6b65424a07c241677eb99c0 418 Gene3D G3DSA:1.20.1250.20 32 201 2.8E-18 T 06-07-2017 CAL12_RS10095 d579b381a6b65424a07c241677eb99c0 418 Gene3D G3DSA:1.20.1250.20 237 406 1.7E-17 T 06-07-2017 CAL12_RS10095 d579b381a6b65424a07c241677eb99c0 418 Pfam PF07690 Major Facilitator Superfamily 37 373 1.0E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS10095 d579b381a6b65424a07c241677eb99c0 418 SUPERFAMILY SSF103473 21 407 3.27E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS15625 b456998a0d7b820a6a6091299e3c883d 495 Pfam PF00171 Aldehyde dehydrogenase family 39 488 1.5E-137 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS15625 b456998a0d7b820a6a6091299e3c883d 495 Gene3D G3DSA:3.40.309.10 282 465 4.9E-58 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS15625 b456998a0d7b820a6a6091299e3c883d 495 Gene3D G3DSA:3.40.605.10 23 281 1.9E-70 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS15625 b456998a0d7b820a6a6091299e3c883d 495 SUPERFAMILY SSF53720 19 492 2.75E-133 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS08435 a382ea7ff47daab1d5e661a2eacfd3bf 321 Gene3D G3DSA:3.20.20.100 47 314 1.2E-41 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS08435 a382ea7ff47daab1d5e661a2eacfd3bf 321 Pfam PF00248 Aldo/keto reductase family 62 312 7.6E-28 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS08435 a382ea7ff47daab1d5e661a2eacfd3bf 321 SUPERFAMILY SSF51430 47 313 1.96E-48 T 06-07-2017 IPR023210 NADP-dependent oxidoreductase domain CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 Pfam PF02096 60Kd inner membrane protein 378 556 1.7E-57 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 558 24.547 T 06-07-2017 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 275 290 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 486 508 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 439 462 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 186 206 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 348 368 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 2 23 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 240 258 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR00701 60kDa inner membrane protein signature 522 545 2.2E-64 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 377 556 4.0E-68 T 06-07-2017 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 3 376 2.2E-113 T 06-07-2017 IPR028053 Membrane insertase YidC, N-terminal CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR01900 YidC translocation/secretion protein signature 363 379 1.1E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR01900 YidC translocation/secretion protein signature 511 535 1.1E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 PRINTS PR01900 YidC translocation/secretion protein signature 492 507 1.1E-20 T 06-07-2017 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CAL12_RS27970 73aefe4efe73479a9e6cc9a3b0892baf 567 Pfam PF14849 YidC periplasmic domain 93 366 3.2E-85 T 06-07-2017 IPR028053 Membrane insertase YidC, N-terminal CAL12_RS13145 2754a41938fb458af2b3bf9c03811a33 851 Pfam PF05650 Domain of unknown function (DUF802) 459 511 1.9E-18 T 06-07-2017 IPR008520 Domain of unknown function DUF802 CAL12_RS13145 2754a41938fb458af2b3bf9c03811a33 851 Pfam PF05650 Domain of unknown function (DUF802) 514 566 1.4E-12 T 06-07-2017 IPR008520 Domain of unknown function DUF802 CAL12_RS13145 2754a41938fb458af2b3bf9c03811a33 851 SUPERFAMILY SSF58113 326 513 5.75E-5 T 06-07-2017 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 SUPERFAMILY SSF46785 8 93 7.43E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 4.1E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 Pfam PF03466 LysR substrate binding domain 94 288 2.4E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.2E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 Gene3D G3DSA:1.10.10.10 8 93 2.3E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 Gene3D G3DSA:3.40.190.10 184 270 5.6E-32 T 06-07-2017 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 SUPERFAMILY SSF53850 95 290 6.6E-31 T 06-07-2017 CAL12_RS20860 c6de45d843b5a1b030a52e34940ac7fe 305 Gene3D G3DSA:3.40.190.10 95 183 6.4E-22 T 06-07-2017 CAL12_RS19690 4f15e7caec6002f721d21172c07cf060 164 PIRSF PIRSF000216 2 164 3.0E-53 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19690 4f15e7caec6002f721d21172c07cf060 164 Gene3D G3DSA:3.40.30.10 76 161 2.6E-6 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19690 4f15e7caec6002f721d21172c07cf060 164 SUPERFAMILY SSF52833 3 159 8.95E-49 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19690 4f15e7caec6002f721d21172c07cf060 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 13 157 1.3E-45 T 06-07-2017 CAL12_RS19690 4f15e7caec6002f721d21172c07cf060 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 157 6.5E-55 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS18285 1ce7f0713913a8f532717809ccecb5c3 105 SUPERFAMILY SSF50249 1 94 6.28E-15 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18285 1ce7f0713913a8f532717809ccecb5c3 105 Gene3D G3DSA:2.40.50.140 1 99 8.9E-25 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS18285 1ce7f0713913a8f532717809ccecb5c3 105 PIRSF PIRSF003135 1 97 8.9E-15 T 06-07-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CAL12_RS18285 1ce7f0713913a8f532717809ccecb5c3 105 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 9.4E-30 T 06-07-2017 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Gene3D G3DSA:2.30.40.10 4 65 4.0E-14 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 SUPERFAMILY SSF51338 413 466 4.93E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 SUPERFAMILY SSF51338 4 55 4.93E-20 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Gene3D G3DSA:3.20.20.140 338 393 2.9E-109 T 06-07-2017 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Gene3D G3DSA:3.20.20.140 66 279 2.9E-109 T 06-07-2017 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Gene3D G3DSA:2.30.40.10 394 473 2.1E-13 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 SUPERFAMILY SSF51556 56 413 3.24E-86 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Pfam PF07969 Amidohydrolase family 344 457 4.2E-19 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Pfam PF07969 Amidohydrolase family 46 207 1.5E-17 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS12305 633d3eed201242a7c482b0e0d1134428 482 Gene3D G3DSA:3.30.1490.130 282 337 1.7E-23 T 06-07-2017 IPR023100 D-aminoacylase, insert domain GO:0016811 CAL12_RS06205 552562b5b6232897af9274b24de1ff62 139 Gene3D G3DSA:1.10.10.10 5 82 3.2E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06205 552562b5b6232897af9274b24de1ff62 139 Pfam PF01475 Ferric uptake regulator family 10 129 1.8E-44 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAL12_RS06205 552562b5b6232897af9274b24de1ff62 139 SUPERFAMILY SSF46785 5 134 2.42E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS02985 ae22f14d6682a2f7c18fcfadcf14cbf5 179 Pfam PF02464 Competence-damaged protein 10 166 7.0E-55 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS02985 ae22f14d6682a2f7c18fcfadcf14cbf5 179 Gene3D G3DSA:3.90.950.20 5 167 2.0E-54 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS02985 ae22f14d6682a2f7c18fcfadcf14cbf5 179 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 16 163 1.9E-42 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS02985 ae22f14d6682a2f7c18fcfadcf14cbf5 179 SUPERFAMILY SSF142433 4 166 3.92E-52 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS17315 f9694b30d51cd1c4b7b3fee4308080df 213 Pfam PF09335 SNARE associated Golgi protein 39 163 2.0E-15 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAL12_RS13675 410e4f90aba5e3f1e2dd946d94faa694 474 Pfam PF03972 MmgE/PrpD family 9 443 1.4E-58 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS13675 410e4f90aba5e3f1e2dd946d94faa694 474 SUPERFAMILY SSF103378 8 455 1.31E-56 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS13675 410e4f90aba5e3f1e2dd946d94faa694 474 Gene3D G3DSA:3.30.1330.120 288 413 1.5E-10 T 06-07-2017 CAL12_RS25690 9b55fc32386ea3c2664583f894a9ca7c 183 Gene3D G3DSA:3.40.50.2020 6 180 5.0E-68 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS25690 9b55fc32386ea3c2664583f894a9ca7c 183 SUPERFAMILY SSF53271 10 179 1.1E-52 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS25690 9b55fc32386ea3c2664583f894a9ca7c 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 36.1 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAL12_RS25690 9b55fc32386ea3c2664583f894a9ca7c 183 Pfam PF00156 Phosphoribosyl transferase domain 50 155 6.2E-18 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS25690 9b55fc32386ea3c2664583f894a9ca7c 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 176 1.1E-65 T 06-07-2017 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|Reactome: R-HSA-74217 CAL12_RS18080 72cc2cdb4e49d89c916597da6ddadb7f 142 Pfam PF01152 Bacterial-like globin 19 138 1.7E-40 T 06-07-2017 IPR001486 Truncated hemoglobin GO:0019825 CAL12_RS18080 72cc2cdb4e49d89c916597da6ddadb7f 142 Gene3D G3DSA:1.10.490.10 18 140 1.5E-41 T 06-07-2017 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 CAL12_RS18080 72cc2cdb4e49d89c916597da6ddadb7f 142 SUPERFAMILY SSF46458 19 140 1.64E-34 T 06-07-2017 IPR009050 Globin-like CAL12_RS09335 6da85270afe04377c37f64db0a432d2f 681 Pfam PF03169 OPT oligopeptide transporter protein 15 633 8.5E-103 T 06-07-2017 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CAL12_RS09335 6da85270afe04377c37f64db0a432d2f 681 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 9 633 1.0E-108 T 06-07-2017 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CAL12_RS09335 6da85270afe04377c37f64db0a432d2f 681 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 635 1.8E-218 T 06-07-2017 IPR004814 Oligopeptide transporter OPT CAL12_RS12280 dbfcc71b783633b9a645fc7de28e0ac8 255 Pfam PF00005 ABC transporter 22 181 4.3E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS12280 dbfcc71b783633b9a645fc7de28e0ac8 255 SUPERFAMILY SSF52540 4 253 5.33E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12280 dbfcc71b783633b9a645fc7de28e0ac8 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 9.8E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS12280 dbfcc71b783633b9a645fc7de28e0ac8 255 SMART SM00382 30 231 2.9E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS12280 dbfcc71b783633b9a645fc7de28e0ac8 255 Gene3D G3DSA:3.40.50.300 2 251 1.8E-69 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 Gene3D G3DSA:3.40.1280.10 111 255 8.2E-45 T 06-07-2017 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 Gene3D G3DSA:3.30.1330.30 3 100 2.5E-11 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 SUPERFAMILY SSF75217 95 256 2.55E-39 T 06-07-2017 IPR029028 Alpha/beta knot methyltransferases CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 SMART SM00967 30 104 0.0045 T 06-07-2017 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 Pfam PF00588 SpoU rRNA Methylase family 113 250 2.6E-33 T 06-07-2017 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CAL12_RS12190 5d5927e344d2d45ad7bd17c97b2c47a3 263 SUPERFAMILY SSF55315 2 102 3.18E-12 T 06-07-2017 IPR029064 50S ribosomal protein L30e-like CAL12_RS07925 fa67ff42306e461608371c7f39b306b3 240 SUPERFAMILY SSF55068 50 221 3.01E-67 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS07925 fa67ff42306e461608371c7f39b306b3 240 Gene3D G3DSA:3.30.1060.10 42 208 1.4E-67 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS07925 fa67ff42306e461608371c7f39b306b3 240 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 57 207 4.5E-53 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS07925 fa67ff42306e461608371c7f39b306b3 240 Pfam PF01625 Peptide methionine sulfoxide reductase 58 208 7.8E-57 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS07925 fa67ff42306e461608371c7f39b306b3 240 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 56 216 35.249 T 06-07-2017 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 SUPERFAMILY SSF54826 1 138 4.6E-18 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 Gene3D G3DSA:3.30.390.10 1 120 2.0E-28 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 SMART SM00922 161 258 1.5E-18 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 Pfam PF13378 Enolase C-terminal domain-like 164 373 2.7E-38 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 SUPERFAMILY SSF51604 122 379 1.31E-48 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 133 2.4E-4 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS05950 7d752ea61cd58094405cd751b14570d3 388 Gene3D G3DSA:3.20.20.120 121 379 5.7E-52 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS11885 e9cd5d927d4d29a3f14ac8fbf80180c5 237 Pfam PF13144 Chaperone for flagella basal body P-ring formation 38 235 6.0E-48 T 06-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CAL12_RS11885 e9cd5d927d4d29a3f14ac8fbf80180c5 237 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 101 235 3.1E-38 T 06-07-2017 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal CAL12_RS11885 e9cd5d927d4d29a3f14ac8fbf80180c5 237 SMART SM00858 113 175 9.6E-12 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS26585 016e2a95053201e0365ad116686bdaf4 476 SUPERFAMILY SSF56059 322 467 2.83E-59 T 06-07-2017 CAL12_RS26585 016e2a95053201e0365ad116686bdaf4 476 SUPERFAMILY SSF56059 20 215 2.83E-59 T 06-07-2017 CAL12_RS26585 016e2a95053201e0365ad116686bdaf4 476 Pfam PF14403 Circularly permuted ATP-grasp type 2 77 452 1.2E-164 T 06-07-2017 IPR025841 Circularly permuted ATP-grasp type 2 CAL12_RS26585 016e2a95053201e0365ad116686bdaf4 476 PIRSF PIRSF005522 2 476 1.7E-228 T 06-07-2017 IPR016450 Uncharacterised conserved protein UCP005522 CAL12_RS21465 bb80c8b2bcbdcc03c9aec618a5d00c8b 511 Pfam PF02321 Outer membrane efflux protein 70 271 8.6E-21 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS21465 bb80c8b2bcbdcc03c9aec618a5d00c8b 511 Pfam PF02321 Outer membrane efflux protein 298 478 2.8E-10 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS21465 bb80c8b2bcbdcc03c9aec618a5d00c8b 511 Gene3D G3DSA:1.20.1600.10 66 478 3.7E-34 T 06-07-2017 CAL12_RS21465 bb80c8b2bcbdcc03c9aec618a5d00c8b 511 SUPERFAMILY SSF56954 11 479 9.02E-52 T 06-07-2017 CAL12_RS15480 5d95353f4257740c64fa08a905e9af4d 1207 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 184 1.6E-60 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS15480 5d95353f4257740c64fa08a905e9af4d 1207 Pfam PF02538 Hydantoinase B/oxoprolinase 689 1206 1.5E-197 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS15480 5d95353f4257740c64fa08a905e9af4d 1207 Pfam PF01968 Hydantoinase/oxoprolinase 203 490 2.2E-115 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS14940 ad43c78894fbb4631a66fbdc5c77df35 398 Gene3D G3DSA:3.90.850.10 185 372 9.1E-19 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14940 ad43c78894fbb4631a66fbdc5c77df35 398 SUPERFAMILY SSF56529 169 376 4.97E-23 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS27730 88743ed3b492697aded0630d9a667982 153 SUPERFAMILY SSF55729 3 148 1.21E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS27730 88743ed3b492697aded0630d9a667982 153 Pfam PF00583 Acetyltransferase (GNAT) family 59 141 4.9E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS27730 88743ed3b492697aded0630d9a667982 153 Gene3D G3DSA:3.40.630.30 3 152 4.9E-44 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS11140 3aa637d50b2d6fa3389f2e1543449055 126 SUPERFAMILY SSF54593 3 121 4.05E-22 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS11140 3aa637d50b2d6fa3389f2e1543449055 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 121 8.1E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS11140 3aa637d50b2d6fa3389f2e1543449055 126 Gene3D G3DSA:3.10.180.10 6 123 7.3E-27 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS15530 0adfd4c46177f7b4f34aa1ee2009da11 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 292 7.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15530 0adfd4c46177f7b4f34aa1ee2009da11 293 SUPERFAMILY SSF161098 55 282 1.57E-49 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15530 0adfd4c46177f7b4f34aa1ee2009da11 293 Gene3D G3DSA:1.10.3720.10 61 290 3.9E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS17000 3e46616e054b923f8b6d66e8bca93910 138 Pfam PF07883 Cupin domain 51 124 1.5E-15 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS17000 3e46616e054b923f8b6d66e8bca93910 138 SUPERFAMILY SSF51182 32 130 5.4E-19 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS17000 3e46616e054b923f8b6d66e8bca93910 138 Gene3D G3DSA:2.60.120.10 36 131 1.3E-20 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Gene3D G3DSA:3.30.1490.20 141 195 2.3E-30 T 06-07-2017 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 124 1.0E-34 T 06-07-2017 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 SUPERFAMILY SSF52440 1 126 1.41E-31 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 316 1.2E-120 T 06-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 SUPERFAMILY SSF56059 128 315 3.33E-57 T 06-07-2017 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Hamap MF_00162 Glutathione synthetase [gshB]. 1 319 152.337 T 06-07-2017 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Gene3D G3DSA:3.30.470.20 196 304 1.6E-45 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Gene3D G3DSA:3.40.50.20 1 133 6.9E-40 T 06-07-2017 IPR016185 Pre-ATP-grasp domain CAL12_RS09760 c381f467b38288fd743c6382555b0fe5 319 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 128 301 1.5E-74 T 06-07-2017 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 CAL12_RS05190 8b4bf70ed7c7e5135485fc4c508abd82 180 Pfam PF13689 Domain of unknown function (DUF4154) 38 175 9.1E-31 T 06-07-2017 IPR025293 Protein of unknown function DUF4154 CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 Gene3D G3DSA:1.10.10.10 2 77 6.5E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 Pfam PF07729 FCD domain 98 220 5.9E-26 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 SMART SM00345 14 73 6.9E-22 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.0E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.0E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 SUPERFAMILY SSF46785 1 77 1.7E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 Gene3D G3DSA:1.20.120.530 97 230 1.8E-28 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 3.8E-21 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 SUPERFAMILY SSF48008 97 229 1.78E-26 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS17495 df8789137a8439b3e522c0c18419aa41 233 SMART SM00895 95 222 8.6E-21 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 Pfam PF01019 Gamma-glutamyltranspeptidase 33 573 2.6E-117 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 466 483 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 272 291 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 110 128 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 147 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 389 407 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 243 259 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 40 65 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 442 457 6.2E-35 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09780 dc0b2538c0f534a65e782996c77a5ce8 580 SUPERFAMILY SSF56235 4 580 9.07E-141 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS17970 904606783610ca07e2ec28b7dae9b102 374 Pfam PF00534 Glycosyl transferases group 1 189 344 2.5E-21 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS17970 904606783610ca07e2ec28b7dae9b102 374 SUPERFAMILY SSF53756 3 364 7.85E-67 T 06-07-2017 CAL12_RS17970 904606783610ca07e2ec28b7dae9b102 374 Pfam PF13439 Glycosyltransferase Family 4 14 166 2.5E-26 T 06-07-2017 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CAL12_RS17970 904606783610ca07e2ec28b7dae9b102 374 Gene3D G3DSA:3.40.50.2000 156 344 4.3E-22 T 06-07-2017 CAL12_RS02850 8f4f1201082230c50911d6d1d9b465b2 294 SUPERFAMILY SSF56281 140 285 1.12E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS02850 8f4f1201082230c50911d6d1d9b465b2 294 SUPERFAMILY SSF56281 1 113 1.12E-49 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS02850 8f4f1201082230c50911d6d1d9b465b2 294 Gene3D G3DSA:3.60.15.10 1 285 5.5E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS02850 8f4f1201082230c50911d6d1d9b465b2 294 SMART SM00849 18 248 5.7E-5 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS02850 8f4f1201082230c50911d6d1d9b465b2 294 Pfam PF12706 Beta-lactamase superfamily domain 48 240 4.3E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS07535 303e9c19daf26d26711af49e931b3282 252 Pfam PF11127 Protein of unknown function (DUF2892) 28 83 4.8E-5 T 06-07-2017 IPR021309 Protein of unknown function DUF2892 CAL12_RS07535 303e9c19daf26d26711af49e931b3282 252 SUPERFAMILY SSF55961 103 240 4.45E-23 T 06-07-2017 CAL12_RS07535 303e9c19daf26d26711af49e931b3282 252 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 108 217 1.0E-12 T 06-07-2017 IPR005031 Coenzyme Q-binding protein COQ10, START domain CAL12_RS07535 303e9c19daf26d26711af49e931b3282 252 Gene3D G3DSA:3.30.530.20 102 210 8.4E-6 T 06-07-2017 IPR023393 START-like domain CAL12_RS09105 1f9dfe2d71902854239f2d0ca34fc78a 307 SUPERFAMILY SSF51197 34 289 3.39E-65 T 06-07-2017 CAL12_RS09105 1f9dfe2d71902854239f2d0ca34fc78a 307 Gene3D G3DSA:2.60.120.620 34 276 3.1E-59 T 06-07-2017 CAL12_RS09105 1f9dfe2d71902854239f2d0ca34fc78a 307 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 21 296 7.1E-145 T 06-07-2017 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 CAL12_RS09105 1f9dfe2d71902854239f2d0ca34fc78a 307 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 45 260 8.1E-33 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAL12_RS09155 fdf69d8256c85e55a42eb5e5e64cd5d4 603 Pfam PF00437 Type II/IV secretion system protein 234 423 7.3E-22 T 06-07-2017 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CAL12_RS09155 fdf69d8256c85e55a42eb5e5e64cd5d4 603 Gene3D G3DSA:3.40.50.300 283 587 1.1E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09155 fdf69d8256c85e55a42eb5e5e64cd5d4 603 Gene3D G3DSA:3.30.450.90 153 273 1.5E-9 T 06-07-2017 CAL12_RS09155 fdf69d8256c85e55a42eb5e5e64cd5d4 603 SUPERFAMILY SSF52540 167 580 5.8E-36 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18075 36f58d2f20f7cb688610db24107e7863 239 Gene3D G3DSA:1.10.510.10 150 213 1.1E-12 T 06-07-2017 CAL12_RS18075 36f58d2f20f7cb688610db24107e7863 239 SUPERFAMILY SSF56112 56 193 1.75E-17 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS18075 36f58d2f20f7cb688610db24107e7863 239 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 5 236 27.007 T 06-07-2017 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 CAL12_RS18075 36f58d2f20f7cb688610db24107e7863 239 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 44 213 5.4E-40 T 06-07-2017 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 CAL12_RS10900 0d003d1aa0a167b3570b726fd2ff8b6e 360 SUPERFAMILY SSF52218 98 229 1.93E-25 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS10900 0d003d1aa0a167b3570b726fd2ff8b6e 360 SUPERFAMILY SSF52218 256 345 1.93E-25 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS10900 0d003d1aa0a167b3570b726fd2ff8b6e 360 Pfam PF03358 NADPH-dependent FMN reductase 102 298 4.6E-27 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAL12_RS10900 0d003d1aa0a167b3570b726fd2ff8b6e 360 Gene3D G3DSA:3.40.50.360 101 336 1.4E-31 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS27240 115441030198cdcc4dc4f10b790837ef 131 Pfam PF07883 Cupin domain 43 101 6.4E-8 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS27240 115441030198cdcc4dc4f10b790837ef 131 Gene3D G3DSA:2.60.120.10 15 124 1.0E-22 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS27240 115441030198cdcc4dc4f10b790837ef 131 SUPERFAMILY SSF51182 1 125 7.11E-24 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS02060 7c0ae1d98577e49d5586f34e3ef40265 300 Gene3D G3DSA:3.40.50.300 32 250 1.5E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02060 7c0ae1d98577e49d5586f34e3ef40265 300 SUPERFAMILY SSF52540 39 261 1.97E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS02060 7c0ae1d98577e49d5586f34e3ef40265 300 Pfam PF00005 ABC transporter 54 196 4.9E-27 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS02060 7c0ae1d98577e49d5586f34e3ef40265 300 SMART SM00382 63 247 2.6E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 Pfam PF00535 Glycosyl transferase family 2 157 328 2.7E-36 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 SUPERFAMILY SSF53448 156 434 8.44E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 SUPERFAMILY SSF141371 578 668 9.81E-8 T 06-07-2017 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 244 268 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 474 493 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 108 133 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 163 182 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 405 431 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 80 100 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 550 571 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 434 453 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 PRINTS PR01439 Cellulose synthase subunit A signature 514 538 7.9E-62 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 Pfam PF07238 PilZ domain 577 673 1.9E-11 T 06-07-2017 IPR009875 PilZ domain GO:0035438 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 TIGRFAM TIGR03030 CelA: cellulose synthase catalytic subunit (UDP-forming) 33 711 1.2E-278 T 06-07-2017 IPR003919 Cellulose synthase, subunit A GO:0006011|GO:0016020|GO:0016759|GO:0035438 KEGG: 00500+2.4.1.12|MetaCyc: PWY-1001 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 Pfam PF03552 Cellulose synthase 332 536 1.8E-8 T 06-07-2017 IPR005150 Cellulose synthase GO:0016020|GO:0016760|GO:0030244 CAL12_RS00290 3c34a85d083d6559869c3ad3445d5238 745 Gene3D G3DSA:3.90.550.10 154 392 3.8E-21 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS04985 6830a5cab54e5a74e97708732487e656 388 SUPERFAMILY SSF53383 1 385 9.38E-103 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS04985 6830a5cab54e5a74e97708732487e656 388 Pfam PF00155 Aminotransferase class I and II 32 379 7.6E-55 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS04985 6830a5cab54e5a74e97708732487e656 388 Gene3D G3DSA:3.40.640.10 46 268 7.7E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS04985 6830a5cab54e5a74e97708732487e656 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 229 242 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAL12_RS04985 6830a5cab54e5a74e97708732487e656 388 Gene3D G3DSA:3.90.1150.10 269 386 1.2E-28 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS18680 a4f7e6b33c5cfea6c658c9ca2a5e1175 95 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 6 95 4.0E-44 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAL12_RS18680 a4f7e6b33c5cfea6c658c9ca2a5e1175 95 PIRSF PIRSF030200 1 95 4.8E-43 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAL12_RS18680 a4f7e6b33c5cfea6c658c9ca2a5e1175 95 Pfam PF06243 Phenylacetic acid degradation B 6 92 5.9E-40 T 06-07-2017 IPR009359 Phenylacetic acid degradation B CAL12_RS13335 89db256db77cdbf44add55225198f111 251 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS13335 89db256db77cdbf44add55225198f111 251 SMART SM00382 36 219 4.4E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS13335 89db256db77cdbf44add55225198f111 251 Pfam PF00005 ABC transporter 28 171 3.7E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS13335 89db256db77cdbf44add55225198f111 251 SUPERFAMILY SSF52540 9 239 5.1E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13335 89db256db77cdbf44add55225198f111 251 Gene3D G3DSA:3.40.50.300 5 239 4.4E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26850 f42741508e53cf2ec08e90691e248e53 147 Pfam PF04138 GtrA-like protein 29 139 1.6E-12 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAL12_RS15550 de1a8fa3167adfbfaa423f4054ebebbc 199 SUPERFAMILY SSF52218 2 172 8.38E-44 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS15550 de1a8fa3167adfbfaa423f4054ebebbc 199 Gene3D G3DSA:3.40.50.360 2 171 3.5E-41 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS15550 de1a8fa3167adfbfaa423f4054ebebbc 199 Pfam PF02525 Flavodoxin-like fold 2 157 1.1E-37 T 06-07-2017 IPR003680 Flavodoxin-like fold CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 SUPERFAMILY SSF46785 2 79 5.75E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 Pfam PF03466 LysR substrate binding domain 90 289 4.2E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 Gene3D G3DSA:3.40.190.10 176 261 8.8E-21 T 06-07-2017 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 SUPERFAMILY SSF53850 91 290 2.76E-36 T 06-07-2017 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 Gene3D G3DSA:3.40.190.10 90 175 1.2E-20 T 06-07-2017 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.8E-23 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13285 04308705ee79b6b33606d3de2b3bbe54 331 Gene3D G3DSA:1.10.10.10 2 83 2.5E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01175 bc76c5e920c8524122e1aea87da02875 223 Gene3D G3DSA:3.50.30.40 24 183 4.1E-51 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS01175 bc76c5e920c8524122e1aea87da02875 223 Pfam PF03737 Demethylmenaquinone methyltransferase 27 173 1.8E-43 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS01175 bc76c5e920c8524122e1aea87da02875 223 SUPERFAMILY SSF89562 23 184 3.53E-47 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS27200 1249fe9133c586d0983ce35eb3f1b566 324 SUPERFAMILY SSF53850 111 283 8.41E-9 T 06-07-2017 CAL12_RS27200 1249fe9133c586d0983ce35eb3f1b566 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 287 1.3E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27200 1249fe9133c586d0983ce35eb3f1b566 324 PIRSF PIRSF017082 1 323 3.2E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22995 bb3681dc09a8ae10309c4b38c9610190 358 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 87 328 1.2E-32 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS22995 bb3681dc09a8ae10309c4b38c9610190 358 Gene3D G3DSA:3.40.50.2000 175 347 3.6E-49 T 06-07-2017 CAL12_RS22995 bb3681dc09a8ae10309c4b38c9610190 358 Gene3D G3DSA:3.40.50.2000 11 160 1.1E-20 T 06-07-2017 CAL12_RS22995 bb3681dc09a8ae10309c4b38c9610190 358 SUPERFAMILY SSF53756 11 347 5.02E-75 T 06-07-2017 CAL12_RS04285 1624a118b386d0c6cad30fbc6f0a57bb 304 SUPERFAMILY SSF51197 34 303 5.95E-63 T 06-07-2017 CAL12_RS04285 1624a118b386d0c6cad30fbc6f0a57bb 304 Gene3D G3DSA:3.60.130.10 30 303 1.4E-63 T 06-07-2017 CAL12_RS04285 1624a118b386d0c6cad30fbc6f0a57bb 304 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 37 301 2.2E-49 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS04085 6c44ef017fff52592cf6ebc2a32dc302 248 Gene3D G3DSA:3.90.850.10 28 246 4.1E-69 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS04085 6c44ef017fff52592cf6ebc2a32dc302 248 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 43 246 1.8E-57 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS04085 6c44ef017fff52592cf6ebc2a32dc302 248 SUPERFAMILY SSF56529 30 247 2.35E-63 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 353 6.3E-91 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 211 220 - T 06-07-2017 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 Gene3D G3DSA:3.90.1150.10 257 355 2.0E-25 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 Gene3D G3DSA:3.40.640.10 38 256 5.2E-65 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 355 57.164 T 06-07-2017 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 Pfam PF00155 Aminotransferase class I and II 25 351 6.0E-57 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS09245 1bce08701ed5c07bb4a1688927a7744b 356 SUPERFAMILY SSF53383 5 355 8.53E-80 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS08780 ee97f00c2215cc248f1228576d41d73e 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 56 5.4E-26 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08780 ee97f00c2215cc248f1228576d41d73e 56 SUPERFAMILY SSF57829 3 54 1.16E-18 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAL12_RS08780 ee97f00c2215cc248f1228576d41d73e 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 14.301 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08780 ee97f00c2215cc248f1228576d41d73e 56 Pfam PF00471 Ribosomal protein L33 8 54 9.0E-17 T 06-07-2017 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27250 0ed2e1d0e45b72b6c968bcfb278a23b5 321 SUPERFAMILY SSF53850 109 286 4.24E-10 T 06-07-2017 CAL12_RS27250 0ed2e1d0e45b72b6c968bcfb278a23b5 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 317 7.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27250 0ed2e1d0e45b72b6c968bcfb278a23b5 321 PIRSF PIRSF017082 1 321 5.8E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13310 eeddc1334f82d61592c1651d9bd8c521 482 Pfam PF03972 MmgE/PrpD family 123 408 3.5E-25 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS13310 eeddc1334f82d61592c1651d9bd8c521 482 SUPERFAMILY SSF103378 122 410 3.01E-34 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 SUPERFAMILY SSF56176 2 173 4.69E-46 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 Gene3D G3DSA:3.30.43.10 1 54 4.4E-14 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 Gene3D G3DSA:3.30.390.50 191 285 1.9E-12 T 06-07-2017 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 SUPERFAMILY SSF55447 181 285 4.19E-10 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 Gene3D G3DSA:3.30.465.10 66 173 1.8E-28 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 205 283 1.0E-4 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 173 8.6E-42 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS10350 86093d6ecf027759d67b069b5655eca8 287 SMART SM01092 182 285 6.3E-9 T 06-07-2017 IPR005107 CO dehydrogenase flavoprotein, C-terminal CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 251 2.2E-36 T 06-07-2017 CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.8E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 SUPERFAMILY SSF51735 3 251 8.82E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25220 97ab3f3b226f0ac427068e798eed4cb0 256 Gene3D G3DSA:3.40.50.720 2 251 4.7E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01245 ab5dfede5c1924d222722e63170c89d2 293 Pfam PF10001 Uncharacterized protein conserved in bacteria (DUF2242) 69 191 7.1E-48 T 06-07-2017 IPR018718 Protein of unknown function DUF2242 CAL12_RS22190 7bd141b4e6ff1557585fe3b7a05ed1ba 218 SUPERFAMILY SSF161098 10 203 3.14E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22190 7bd141b4e6ff1557585fe3b7a05ed1ba 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 8.9E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22190 7bd141b4e6ff1557585fe3b7a05ed1ba 218 Gene3D G3DSA:1.10.3720.10 10 216 4.5E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 Gene3D G3DSA:1.10.3360.10 265 345 8.3E-7 T 06-07-2017 IPR023289 VPA0735-like domain CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 Gene3D G3DSA:2.60.40.1610 112 225 4.4E-19 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 Pfam PF06742 Protein of unknown function (DUF1214) 396 502 1.4E-36 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 Gene3D G3DSA:2.60.120.600 354 516 5.7E-55 T 06-07-2017 IPR010621 Domain of unknown function DUF1214 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 SUPERFAMILY SSF160935 259 516 4.18E-116 T 06-07-2017 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 SUPERFAMILY SSF160935 42 229 4.18E-116 T 06-07-2017 CAL12_RS25835 498bc01c2aef28b3695f93abdb451403 517 Pfam PF06863 Protein of unknown function (DUF1254) 93 223 2.7E-40 T 06-07-2017 IPR010679 Domain of unknown function DUF1254 CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 240 314 2.8E-19 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 Pfam PF00005 ABC transporter 33 189 9.8E-24 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 SUPERFAMILY SSF52540 12 260 1.47E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 Gene3D G3DSA:3.40.50.300 11 263 5.5E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 SMART SM00382 41 239 8.7E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS24315 2c144de07501a0aa8c785adeb8f7b24c 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 9.2E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS05455 f2f61ce7eb4cdd7aaf57d360b4e8ab92 320 SUPERFAMILY SSF51735 14 289 4.06E-24 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05455 f2f61ce7eb4cdd7aaf57d360b4e8ab92 320 Gene3D G3DSA:3.90.25.10 192 281 3.0E-4 T 06-07-2017 CAL12_RS05455 f2f61ce7eb4cdd7aaf57d360b4e8ab92 320 Pfam PF05368 NmrA-like family 15 247 3.5E-18 T 06-07-2017 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CAL12_RS05455 f2f61ce7eb4cdd7aaf57d360b4e8ab92 320 Gene3D G3DSA:3.40.50.720 14 191 5.3E-15 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 SUPERFAMILY SSF103473 24 437 5.49E-65 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 Gene3D G3DSA:1.20.1250.20 24 232 1.1E-24 T 06-07-2017 CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 Gene3D G3DSA:1.20.1250.20 247 436 3.0E-26 T 06-07-2017 CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 Pfam PF07690 Major Facilitator Superfamily 32 272 8.5E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS21050 1105111fcb72922d728ab3289b163b16 441 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 322 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS04140 959dc1eb3b35c3938252a341c0ed1be8 573 SUPERFAMILY SSF75304 22 417 4.32E-106 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04140 959dc1eb3b35c3938252a341c0ed1be8 573 Pfam PF01425 Amidase 32 404 6.1E-85 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04140 959dc1eb3b35c3938252a341c0ed1be8 573 Gene3D G3DSA:3.90.1300.10 31 419 3.5E-107 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS04140 959dc1eb3b35c3938252a341c0ed1be8 573 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 31 566 1.1E-231 T 06-07-2017 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 CAL12_RS03255 fc264def2441db3e5c76198a8c461a53 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 283 8.6E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03255 fc264def2441db3e5c76198a8c461a53 295 SUPERFAMILY SSF161098 55 279 8.5E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03255 fc264def2441db3e5c76198a8c461a53 295 Gene3D G3DSA:1.10.3720.10 61 289 3.7E-58 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03265 c6e6dbcf5a40411cb00efff74743bf8a 151 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 144 3.6E-48 T 06-07-2017 IPR003791 Protein of unknown function UPF0178 CAL12_RS03265 c6e6dbcf5a40411cb00efff74743bf8a 151 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.139 T 06-07-2017 IPR003791 Protein of unknown function UPF0178 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Pfam PF00501 AMP-binding enzyme 10 412 3.3E-80 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Gene3D G3DSA:3.40.50.980 6 167 3.4E-30 T 06-07-2017 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Gene3D G3DSA:3.40.50.980 168 322 6.7E-36 T 06-07-2017 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 SUPERFAMILY SSF56801 6 503 1.14E-126 T 06-07-2017 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Gene3D G3DSA:3.30.300.30 407 502 2.8E-30 T 06-07-2017 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Gene3D G3DSA:2.30.38.10 326 405 9.2E-17 T 06-07-2017 CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS03320 cf23372f0f96711da0bd6b6a90b3019c 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 495 1.6E-18 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS05095 9da5e8fad6ce96fe0feacf4d37f84f79 354 PIRSF PIRSF017082 24 354 2.3E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05095 9da5e8fad6ce96fe0feacf4d37f84f79 354 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 78 350 8.2E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05095 9da5e8fad6ce96fe0feacf4d37f84f79 354 SUPERFAMILY SSF53850 140 315 2.67E-15 T 06-07-2017 CAL12_RS13810 2f456824b933502d701d462ff2b90ae9 185 Gene3D G3DSA:3.40.50.720 5 141 5.0E-8 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03110 a9ffdf5926b5344c925bce63154cc755 182 Pfam PF14280 Domain of unknown function (DUF4365) 12 168 3.7E-15 T 06-07-2017 IPR025375 Domain of unknown function DUF4365 CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 9 126 1.9E-15 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 SUPERFAMILY SSF54826 1 127 4.88E-26 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 Gene3D G3DSA:3.20.20.120 122 360 1.5E-71 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 Pfam PF13378 Enolase C-terminal domain-like 149 354 1.9E-58 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 193 224 - T 06-07-2017 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 SMART SM00922 146 243 9.8E-25 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 Gene3D G3DSA:3.30.390.10 1 121 9.4E-29 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS15045 621aef1ec7f8e703b1e9af0416e46121 361 SUPERFAMILY SSF51604 114 360 2.62E-68 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS11120 91c655c6957990520e356774e74d4c2b 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 2.7E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11120 91c655c6957990520e356774e74d4c2b 328 PIRSF PIRSF017082 1 327 5.1E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11120 91c655c6957990520e356774e74d4c2b 328 SUPERFAMILY SSF53850 113 286 6.77E-17 T 06-07-2017 CAL12_RS11120 91c655c6957990520e356774e74d4c2b 328 Gene3D G3DSA:3.40.190.10 130 230 1.8E-5 T 06-07-2017 CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 SUPERFAMILY SSF53335 3 265 4.33E-56 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 Gene3D G3DSA:3.40.50.150 80 266 8.2E-67 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 Gene3D G3DSA:1.10.8.10 4 78 6.4E-25 T 06-07-2017 CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 Pfam PF13847 Methyltransferase domain 106 238 2.4E-15 T 06-07-2017 IPR025714 Methyltransferase domain CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 265 4.9E-73 T 06-07-2017 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 17 265 4.0E-89 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 4 270 44.311 T 06-07-2017 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CAL12_RS25880 a7b4c5a3efb979ffd857ac9ed68f1b5e 270 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 175 181 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 SUPERFAMILY SSF51735 3 256 3.5E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.1E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 Gene3D G3DSA:3.40.50.720 3 254 7.8E-59 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS02080 f4bea5c713562505fda72efcb67cde5d 261 Pfam PF00106 short chain dehydrogenase 8 196 4.2E-35 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 Pfam PF02576 Putative ribosome maturation factor RimP 9 151 2.5E-32 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 SUPERFAMILY SSF75420 3 74 9.55E-15 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 2 155 21.034 T 06-07-2017 IPR003728 Ribosome maturation factor RimP GO:0042274 CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 Gene3D G3DSA:2.30.30.180 79 151 1.6E-10 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 SUPERFAMILY SSF74942 75 155 8.63E-11 T 06-07-2017 IPR028998 Ribosome maturation factor RimP, C-terminal CAL12_RS18440 2772a5feaa84085696c96b06830054a4 162 Gene3D G3DSA:3.30.300.70 3 71 6.9E-14 T 06-07-2017 IPR028989 Ribosome maturation factor RimP, N-terminal CAL12_RS13160 a083ae47d9c62930c6c40e2405d564d9 376 Pfam PF03022 Major royal jelly protein 115 366 1.5E-18 T 06-07-2017 IPR017996 Major royal jelly protein/protein yellow CAL12_RS13160 a083ae47d9c62930c6c40e2405d564d9 376 SUPERFAMILY SSF63829 34 343 9.15E-24 T 06-07-2017 CAL12_RS13160 a083ae47d9c62930c6c40e2405d564d9 376 Gene3D G3DSA:2.120.10.30 41 372 1.5E-83 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS18005 7ea3336c8837417d0a818c3fc79b3ee3 598 Pfam PF03961 Protein of unknown function (DUF342) 141 595 4.7E-108 T 06-07-2017 IPR005646 Protein of unknown function DUF342 CAL12_RS08845 38347937961523bc4186efef5fb0af09 329 Pfam PF04392 ABC transporter substrate binding protein 36 327 9.7E-106 T 06-07-2017 IPR007487 ABC transporter, substrate-binding protein CAL12_RS08845 38347937961523bc4186efef5fb0af09 329 Gene3D G3DSA:3.40.50.2300 164 293 2.4E-49 T 06-07-2017 CAL12_RS08845 38347937961523bc4186efef5fb0af09 329 Gene3D G3DSA:3.40.50.2300 35 163 1.1E-55 T 06-07-2017 CAL12_RS08845 38347937961523bc4186efef5fb0af09 329 SUPERFAMILY SSF53822 43 290 2.2E-19 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS15575 95a2755e3954510ec6249ce122602b72 182 Pfam PF00578 AhpC/TSA family 26 154 9.0E-22 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS15575 95a2755e3954510ec6249ce122602b72 182 Gene3D G3DSA:3.40.30.10 24 175 1.2E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS15575 95a2755e3954510ec6249ce122602b72 182 SUPERFAMILY SSF52833 24 175 9.49E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 Gene3D G3DSA:3.40.50.720 3 242 5.2E-77 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 SUPERFAMILY SSF51735 2 243 4.45E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 197 0.0049 T 06-07-2017 CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.8E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 3.3E-64 T 06-07-2017 CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS10595 8c34ed0028c2b877794b8f8238b3b6b0 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.1E-40 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS17375 4c39274b593d67d746d3a8842221f094 566 Pfam PF02470 MlaD protein 303 418 2.3E-13 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS17375 4c39274b593d67d746d3a8842221f094 566 Pfam PF02470 MlaD protein 51 140 2.5E-12 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS17375 4c39274b593d67d746d3a8842221f094 566 Pfam PF02470 MlaD protein 175 242 4.3E-8 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 294 2.3E-16 T 06-07-2017 IPR020801 Polyketide synthase, acyl transferase domain CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 Gene3D G3DSA:3.40.366.10 2 116 7.9E-42 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 Gene3D G3DSA:3.40.366.10 191 284 7.9E-42 T 06-07-2017 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 SUPERFAMILY SSF52151 3 122 8.2E-45 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 SUPERFAMILY SSF52151 192 279 8.2E-45 T 06-07-2017 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 PIRSF PIRSF000446 1 303 6.8E-57 T 06-07-2017 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 TIGRFAM TIGR03131 malonate_mdcH: malonate decarboxylase, epsilon subunit 4 299 1.4E-97 T 06-07-2017 IPR017554 Malonate decarboxylase, McdH subunit CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 SUPERFAMILY SSF55048 123 191 1.28E-11 T 06-07-2017 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 Gene3D G3DSA:3.30.70.250 123 190 4.6E-17 T 06-07-2017 CAL12_RS18765 31c8904e2104627d1523bd5ca019fad0 307 Pfam PF00698 Acyl transferase domain 5 290 1.0E-23 T 06-07-2017 IPR014043 Acyl transferase CAL12_RS05770 20a09b1a1f4d1047d78b1bac1da02a49 247 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 231 7.9E-38 T 06-07-2017 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 CAL12_RS05770 20a09b1a1f4d1047d78b1bac1da02a49 247 PIRSF PIRSF037208 3 245 2.6E-87 T 06-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic CAL12_RS05770 20a09b1a1f4d1047d78b1bac1da02a49 247 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 3 240 44.926 T 06-07-2017 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic CAL12_RS05770 20a09b1a1f4d1047d78b1bac1da02a49 247 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 2.5E-19 T 06-07-2017 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 CAL12_RS05770 20a09b1a1f4d1047d78b1bac1da02a49 247 SUPERFAMILY SSF55729 84 239 1.7E-20 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS12395 dd358243a5811295523d65bcc09ee158 353 Pfam PF01594 Domain of unknown function DUF20 14 341 1.2E-54 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAL12_RS02300 1fd4a7a1955ec90e03bc976e9e2cd65b 295 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 17 288 1.9E-69 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS02300 1fd4a7a1955ec90e03bc976e9e2cd65b 295 SUPERFAMILY SSF51197 15 294 1.42E-88 T 06-07-2017 CAL12_RS02300 1fd4a7a1955ec90e03bc976e9e2cd65b 295 Gene3D G3DSA:3.60.130.10 3 294 2.2E-94 T 06-07-2017 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 SUPERFAMILY SSF52540 3 429 4.89E-170 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Gene3D G3DSA:1.10.300.10 104 196 6.9E-34 T 06-07-2017 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Gene3D G3DSA:3.90.170.10 267 425 3.8E-63 T 06-07-2017 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 06-07-2017 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 205.261 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 SMART SM00788 4 424 3.8E-287 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 1.7E-170 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Gene3D G3DSA:3.40.440.10 197 266 1.8E-68 T 06-07-2017 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Gene3D G3DSA:3.40.440.10 3 94 1.8E-68 T 06-07-2017 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 06-07-2017 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS09275 5a4a2a76e966a809241897fb9a5f3ce5 431 Pfam PF00709 Adenylosuccinate synthetase 5 423 1.2E-168 T 06-07-2017 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Gene3D G3DSA:3.40.190.10 93 180 1.3E-19 T 06-07-2017 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Gene3D G3DSA:3.40.190.10 282 309 1.3E-19 T 06-07-2017 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Gene3D G3DSA:1.10.10.10 4 89 1.7E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 SUPERFAMILY SSF53850 93 306 7.06E-31 T 06-07-2017 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 SUPERFAMILY SSF46785 7 88 2.92E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 3.7E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Pfam PF03466 LysR substrate binding domain 99 305 1.6E-14 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 2.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 2.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 2.5E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10710 7702001ac01701b04480f4615c4bb1a6 317 Gene3D G3DSA:3.40.190.10 181 278 1.4E-18 T 06-07-2017 CAL12_RS25285 88926a724110513f57ccbbe54770825f 378 Pfam PF01098 Cell cycle protein 19 374 1.9E-102 T 06-07-2017 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 CAL12_RS25285 88926a724110513f57ccbbe54770825f 378 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 374 5.2E-131 T 06-07-2017 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 CAL12_RS25285 88926a724110513f57ccbbe54770825f 378 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 332 356 - T 06-07-2017 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 Gene3D G3DSA:3.40.30.10 1 96 2.6E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 Pfam PF13410 Glutathione S-transferase, C-terminal domain 139 177 1.1E-5 T 06-07-2017 CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 SUPERFAMILY SSF47616 82 212 6.4E-33 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 Gene3D G3DSA:1.20.1050.10 97 213 1.9E-53 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 82 1.1E-18 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 213 4.5E-94 T 06-07-2017 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-71182 CAL12_RS18610 2da4eb7bc8bbd29ed3c7695b935c74ce 214 SUPERFAMILY SSF52833 1 86 4.99E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 Gene3D G3DSA:3.40.50.300 9 246 2.7E-85 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 Pfam PF00005 ABC transporter 26 175 1.4E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 SUPERFAMILY SSF52540 10 244 1.57E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 SMART SM00382 35 223 1.0E-17 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS10805 2e2490d28b1e7eca2bef12955a20e8ab 253 PIRSF PIRSF039085 7 249 7.8E-110 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS24450 8666e495541102cb2c8a6bfc29a8ae84 178 Pfam PF10003 Integral membrane protein (DUF2244) 37 173 1.1E-29 T 06-07-2017 IPR019253 Protein of unknown function DUF2244, transmembrane CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 SUPERFAMILY SSF102114 160 402 4.32E-59 T 06-07-2017 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 Pfam PF01938 TRAM domain 409 470 2.4E-17 T 06-07-2017 IPR002792 TRAM domain CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 34 470 1.6E-180 T 06-07-2017 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 SMART SM00729 177 398 1.9E-57 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 181 201 - T 06-07-2017 IPR020612 Methylthiotransferase, conserved site GO:0051539 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 33 471 74.644 T 06-07-2017 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 Gene3D G3DSA:3.80.30.20 177 409 8.3E-79 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 Pfam PF04055 Radical SAM superfamily 181 356 1.2E-30 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 34 468 1.3E-149 T 06-07-2017 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 CAL12_RS04875 7ed81d96f5ac5330e44cb2f0dceaa244 480 Pfam PF00919 Uncharacterized protein family UPF0004 34 134 5.5E-30 T 06-07-2017 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 CAL12_RS03595 d32072b065b5ba45a3d9b4cc676572e3 324 SUPERFAMILY SSF53850 109 280 1.59E-12 T 06-07-2017 CAL12_RS03595 d32072b065b5ba45a3d9b4cc676572e3 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 320 4.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03595 d32072b065b5ba45a3d9b4cc676572e3 324 Gene3D G3DSA:3.40.190.10 125 227 1.2E-8 T 06-07-2017 CAL12_RS03595 d32072b065b5ba45a3d9b4cc676572e3 324 PIRSF PIRSF017082 1 324 6.6E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24035 b59fdab16fd998ed2db4c0a718359188 343 Gene3D G3DSA:3.90.550.10 30 200 1.6E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS24035 b59fdab16fd998ed2db4c0a718359188 343 Pfam PF00535 Glycosyl transferase family 2 32 192 1.9E-30 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS24035 b59fdab16fd998ed2db4c0a718359188 343 SUPERFAMILY SSF53448 25 267 7.5E-42 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS21905 24e249ca0db3bc3a0538ccd1deff5d15 359 Pfam PF01757 Acyltransferase family 8 318 1.4E-19 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAL12_RS07705 6a28bcf0d846b95a4ea61a8a8cc75fb7 284 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 14 278 49.246 T 06-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS07705 6a28bcf0d846b95a4ea61a8a8cc75fb7 284 Pfam PF00793 DAHP synthetase I family 10 276 2.2E-67 T 06-07-2017 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS07705 6a28bcf0d846b95a4ea61a8a8cc75fb7 284 Gene3D G3DSA:3.20.20.70 18 278 2.4E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS07705 6a28bcf0d846b95a4ea61a8a8cc75fb7 284 SUPERFAMILY SSF51569 9 279 3.76E-102 T 06-07-2017 CAL12_RS07705 6a28bcf0d846b95a4ea61a8a8cc75fb7 284 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 19 276 5.6E-116 T 06-07-2017 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CAL12_RS03745 5240b9ced4b57cad82411f5cf38e5224 498 PIRSF PIRSF012702 1 498 8.2E-145 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS03745 5240b9ced4b57cad82411f5cf38e5224 498 Pfam PF07364 Metallopeptidase family M81 2 280 1.5E-85 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS03745 5240b9ced4b57cad82411f5cf38e5224 498 Pfam PF07171 MlrC C-terminus 300 489 9.0E-48 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS01630 4635882633e1397cb1c97ef36aa78ef4 172 Pfam PF09900 Predicted membrane protein (DUF2127) 24 159 6.4E-39 T 06-07-2017 IPR021125 Protein of unknown function DUF2127 CAL12_RS09980 711b52ee692d230d48364dd65ee06dc4 61 Pfam PF05433 Glycine zipper 2TM domain 23 59 4.5E-9 T 06-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 CAL12_RS13770 738cd6e046afdb081559bd350b5b442e 290 Gene3D G3DSA:3.90.1580.10 1 288 2.3E-90 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAL12_RS13770 738cd6e046afdb081559bd350b5b442e 290 Pfam PF03781 Sulfatase-modifying factor enzyme 1 1 287 1.1E-82 T 06-07-2017 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CAL12_RS13770 738cd6e046afdb081559bd350b5b442e 290 SUPERFAMILY SSF56436 1 288 6.22E-91 T 06-07-2017 IPR016187 C-type lectin fold CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 PIRSF PIRSF000443 37 424 1.3E-144 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 60 415 7.4E-137 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 47 418 48.749 T 06-07-2017 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 SUPERFAMILY SSF53474 54 415 2.26E-102 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 Gene3D G3DSA:3.40.50.1820 72 413 1.7E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25360 47dd361eadec092217e5427dcee32f8a 436 Pfam PF00561 alpha/beta hydrolase fold 90 404 1.7E-33 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 6 365 73.179 T 06-07-2017 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 SUPERFAMILY SSF102114 104 333 2.49E-11 T 06-07-2017 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 PIRSF PIRSF006004 4 379 3.0E-144 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 Pfam PF04055 Radical SAM superfamily 110 296 3.9E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 Gene3D G3DSA:3.20.20.70 106 338 5.9E-11 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS09210 e7562f2063dc6efe8235aae84a35a9bf 410 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 370 2.8E-130 T 06-07-2017 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 Gene3D G3DSA:3.20.20.70 149 284 2.5E-59 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 SUPERFAMILY SSF51690 128 293 1.53E-56 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 SUPERFAMILY SSF54675 18 127 2.79E-30 T 06-07-2017 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 39 126 8.1E-24 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 28 293 7.3E-96 T 06-07-2017 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 128 293 4.2E-58 T 06-07-2017 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 PIRSF PIRSF006250 21 294 1.9E-92 T 06-07-2017 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CAL12_RS24265 f45ebc0231a9b7b74db45f3979dc877a 294 Gene3D G3DSA:3.90.1170.20 18 148 9.9E-44 T 06-07-2017 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CAL12_RS06290 e68564210615516861a1b0370639fb5e 815 Gene3D G3DSA:2.60.450.10 175 207 6.6E-12 T 06-07-2017 CAL12_RS06290 e68564210615516861a1b0370639fb5e 815 Gene3D G3DSA:2.60.450.10 63 142 6.6E-12 T 06-07-2017 CAL12_RS06290 e68564210615516861a1b0370639fb5e 815 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 4 782 19.714 T 06-07-2017 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 CAL12_RS06290 e68564210615516861a1b0370639fb5e 815 Pfam PF04453 Organic solvent tolerance protein 306 706 6.7E-97 T 06-07-2017 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 Gene3D G3DSA:1.10.10.10 1 82 2.3E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 Pfam PF03466 LysR substrate binding domain 89 287 1.8E-35 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 Gene3D G3DSA:3.40.190.10 88 177 1.0E-19 T 06-07-2017 CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 1.2E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 Gene3D G3DSA:3.40.190.10 178 257 8.0E-9 T 06-07-2017 CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 SUPERFAMILY SSF46785 1 109 1.61E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23395 ff8d862c62b93b926d9c1de05f0c2d32 300 SUPERFAMILY SSF53850 89 290 9.46E-36 T 06-07-2017 CAL12_RS20830 e116c370f7aba36f79865be717fde3fe 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 324 2.1E-57 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20830 e116c370f7aba36f79865be717fde3fe 328 PIRSF PIRSF017082 2 328 1.4E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20830 e116c370f7aba36f79865be717fde3fe 328 SUPERFAMILY SSF53850 116 286 2.39E-10 T 06-07-2017 CAL12_RS00115 7dfaf35fbd4c2a65b8806355dc64fb53 325 SUPERFAMILY SSF53850 111 281 9.12E-9 T 06-07-2017 CAL12_RS00115 7dfaf35fbd4c2a65b8806355dc64fb53 325 PIRSF PIRSF017082 3 323 6.4E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00115 7dfaf35fbd4c2a65b8806355dc64fb53 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 4.5E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12455 ae64cbd2dec887e7aa13a2931e4235be 74 Pfam PF04102 SlyX 8 74 9.5E-20 T 06-07-2017 IPR007236 SlyX CAL12_RS12455 ae64cbd2dec887e7aa13a2931e4235be 74 Gene3D G3DSA:1.20.5.300 3 51 1.2E-10 T 06-07-2017 CAL12_RS06830 ae8ebbe0f38bc2aa62495560c53c03f4 153 Pfam PF00583 Acetyltransferase (GNAT) family 59 134 8.0E-12 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS06830 ae8ebbe0f38bc2aa62495560c53c03f4 153 SUPERFAMILY SSF55729 1 135 2.4E-27 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS06830 ae8ebbe0f38bc2aa62495560c53c03f4 153 Gene3D G3DSA:3.40.630.30 1 135 2.9E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 Pfam PF00593 TonB dependent receptor 498 729 7.9E-21 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 Gene3D G3DSA:2.170.130.10 44 203 1.2E-25 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 Gene3D G3DSA:2.40.170.20 207 732 5.9E-104 T 06-07-2017 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 SUPERFAMILY SSF56935 47 732 2.56E-106 T 06-07-2017 CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 Pfam PF07715 TonB-dependent Receptor Plug Domain 90 184 1.3E-13 T 06-07-2017 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 715 732 - T 06-07-2017 IPR010917 TonB-dependent receptor, conserved site CAL12_RS19415 5dd67ca838aeeebe884a13f740c34862 732 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 91 732 8.2E-128 T 06-07-2017 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 CAL12_RS18270 bee84d95637156a54e7bbcfdd9d10635 273 SUPERFAMILY SSF56112 34 177 1.08E-11 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 SUPERFAMILY SSF88659 132 191 1.46E-12 T 06-07-2017 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 Gene3D G3DSA:1.10.10.10 135 190 3.5E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 Pfam PF04542 Sigma-70 region 2 41 107 4.6E-11 T 06-07-2017 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 SUPERFAMILY SSF88946 38 104 1.18E-12 T 06-07-2017 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 39 190 1.1E-15 T 06-07-2017 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 Pfam PF08281 Sigma-70, region 4 138 190 3.6E-15 T 06-07-2017 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CAL12_RS04320 b06dedcfb6ecb7292dee7af417c9759f 199 Gene3D G3DSA:1.10.1740.10 38 108 2.5E-10 T 06-07-2017 CAL12_RS04585 f2ca654ca3c186f3cb6b3dd5521287fb 370 Pfam PF00419 Fimbrial protein 233 370 6.6E-12 T 06-07-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CAL12_RS04585 f2ca654ca3c186f3cb6b3dd5521287fb 370 SUPERFAMILY SSF49401 236 370 7.95E-26 T 06-07-2017 IPR008966 Adhesion domain CAL12_RS04585 f2ca654ca3c186f3cb6b3dd5521287fb 370 Gene3D G3DSA:2.60.40.1090 239 370 5.3E-25 T 06-07-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CAL12_RS14690 2e877449dce9c7c09441517e16b57627 343 Gene3D G3DSA:2.120.10.30 4 327 2.9E-94 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS14690 2e877449dce9c7c09441517e16b57627 343 SUPERFAMILY SSF101898 202 315 1.2E-25 T 06-07-2017 CAL12_RS14690 2e877449dce9c7c09441517e16b57627 343 SUPERFAMILY SSF101898 3 175 1.2E-25 T 06-07-2017 CAL12_RS14690 2e877449dce9c7c09441517e16b57627 343 Pfam PF03022 Major royal jelly protein 76 311 2.4E-25 T 06-07-2017 IPR017996 Major royal jelly protein/protein yellow CAL12_RS01510 c64fea8a15e344a67c2ef3f479f6f68b 333 Pfam PF14226 non-haem dioxygenase in morphine synthesis N-terminal 7 139 5.0E-29 T 06-07-2017 IPR026992 Non-haem dioxygenase N-terminal domain CAL12_RS01510 c64fea8a15e344a67c2ef3f479f6f68b 333 SUPERFAMILY SSF51197 4 328 5.29E-94 T 06-07-2017 CAL12_RS01510 c64fea8a15e344a67c2ef3f479f6f68b 333 Gene3D G3DSA:2.60.120.330 5 328 7.0E-98 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAL12_RS01510 c64fea8a15e344a67c2ef3f479f6f68b 333 Pfam PF03171 2OG-Fe(II) oxygenase superfamily 186 291 4.4E-19 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 190 1.4E-6 T 06-07-2017 CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 Gene3D G3DSA:3.40.30.10 1 86 6.1E-18 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 6.9E-16 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 SUPERFAMILY SSF52833 1 91 5.38E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 SUPERFAMILY SSF47616 73 202 2.9E-17 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS14435 bac149d4dceeb4e17117f9ed9f67abbc 205 Gene3D G3DSA:1.20.1050.10 87 202 7.3E-12 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS13150 710d0a7ade64516cfb975d1c6d788c97 237 Pfam PF00691 OmpA family 92 196 4.8E-19 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS13150 710d0a7ade64516cfb975d1c6d788c97 237 SUPERFAMILY SSF103088 66 200 9.29E-29 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS13150 710d0a7ade64516cfb975d1c6d788c97 237 Gene3D G3DSA:3.30.1330.60 81 200 2.4E-31 T 06-07-2017 IPR006665 OmpA-like domain CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 SUPERFAMILY SSF51735 11 233 8.95E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.2E-25 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 Pfam PF00106 short chain dehydrogenase 14 199 8.4E-44 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 Gene3D G3DSA:3.40.50.720 12 231 4.0E-58 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01290 faadf7120cf17d0e36527e3c166bc6b1 272 PIRSF PIRSF000126 1 263 9.6E-75 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS27395 3386a2f8ace6aefb8b220973ba225c91 174 Pfam PF00436 Single-strand binding protein family 4 109 6.5E-43 T 06-07-2017 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CAL12_RS27395 3386a2f8ace6aefb8b220973ba225c91 174 Gene3D G3DSA:2.40.50.140 1 174 4.2E-57 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS27395 3386a2f8ace6aefb8b220973ba225c91 174 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 38.308 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAL12_RS27395 3386a2f8ace6aefb8b220973ba225c91 174 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 174 1.3E-55 T 06-07-2017 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CAL12_RS27395 3386a2f8ace6aefb8b220973ba225c91 174 SUPERFAMILY SSF50249 3 174 1.27E-60 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS00805 5478a45435124299ecef8bd072725776 116 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 9 98 20.687 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAL12_RS00805 5478a45435124299ecef8bd072725776 116 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 20 101 1.8E-13 T 06-07-2017 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CAL12_RS00805 5478a45435124299ecef8bd072725776 116 SUPERFAMILY SSF101386 25 102 9.35E-23 T 06-07-2017 CAL12_RS00805 5478a45435124299ecef8bd072725776 116 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 12 98 1.4E-27 T 06-07-2017 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CAL12_RS18240 2bf28bb7c0295b492508dd1614b7f3dc 154 Pfam PF00578 AhpC/TSA family 5 131 1.0E-33 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS18240 2bf28bb7c0295b492508dd1614b7f3dc 154 PIRSF PIRSF000239 1 153 2.1E-29 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS18240 2bf28bb7c0295b492508dd1614b7f3dc 154 Gene3D G3DSA:3.40.30.10 2 152 2.0E-46 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18240 2bf28bb7c0295b492508dd1614b7f3dc 154 SUPERFAMILY SSF52833 4 153 4.41E-48 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS05810 e7d72dd96b199e12b667694aa67fbf84 222 Gene3D G3DSA:3.50.30.40 24 181 6.1E-51 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS05810 e7d72dd96b199e12b667694aa67fbf84 222 SUPERFAMILY SSF89562 24 185 2.62E-47 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS05810 e7d72dd96b199e12b667694aa67fbf84 222 Pfam PF03737 Demethylmenaquinone methyltransferase 27 173 1.7E-43 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS19380 843d29a6207ef807806076aca1bcf316 236 Gene3D G3DSA:3.40.30.10 1 102 3.4E-42 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19380 843d29a6207ef807806076aca1bcf316 236 SUPERFAMILY SSF52833 1 84 1.73E-17 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19380 843d29a6207ef807806076aca1bcf316 236 Pfam PF14497 Glutathione S-transferase, C-terminal domain 110 217 4.4E-31 T 06-07-2017 IPR004046 Glutathione S-transferase, C-terminal CAL12_RS19380 843d29a6207ef807806076aca1bcf316 236 SUPERFAMILY SSF47616 84 221 5.89E-24 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS19380 843d29a6207ef807806076aca1bcf316 236 Gene3D G3DSA:1.20.1050.10 103 206 3.4E-54 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS20995 36103607ac67f41eaa53e5166e905d69 207 Pfam PF03928 Haem-degrading 69 199 4.4E-17 T 06-07-2017 IPR005624 Haem-degrading CAL12_RS20995 36103607ac67f41eaa53e5166e905d69 207 SUPERFAMILY SSF143744 61 202 7.59E-24 T 06-07-2017 CAL12_RS16990 d4100002caa917f96a3cfd1ac2f40437 223 SMART SM00471 34 156 0.0086 T 06-07-2017 IPR003607 HD/PDEase domain CAL12_RS16990 d4100002caa917f96a3cfd1ac2f40437 223 SUPERFAMILY SSF109604 38 131 1.07E-18 T 06-07-2017 CAL12_RS16990 d4100002caa917f96a3cfd1ac2f40437 223 Pfam PF01966 HD domain 39 124 2.5E-8 T 06-07-2017 IPR006674 HD domain CAL12_RS16990 d4100002caa917f96a3cfd1ac2f40437 223 Gene3D G3DSA:1.10.3210.10 34 125 6.9E-12 T 06-07-2017 IPR006674 HD domain CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 182 2.9E-13 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 13 173 1.3E-12 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 Gene3D G3DSA:3.40.50.1000 78 205 2.0E-30 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 SUPERFAMILY SSF56784 10 213 3.08E-36 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 2.1E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 2.1E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 2.1E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS01190 75e70a61c901c1fa8d46afb193fb9686 222 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 2.1E-9 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS15760 6d8addcdb81d0ecd91c67c92f598d8cb 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 16 242 2.3E-39 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAL12_RS15760 6d8addcdb81d0ecd91c67c92f598d8cb 249 SUPERFAMILY SSF51695 9 244 7.06E-66 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAL12_RS15760 6d8addcdb81d0ecd91c67c92f598d8cb 249 Gene3D G3DSA:3.20.20.190 7 245 2.0E-65 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAL12_RS26500 2973eee7104695eafacc7fbc69c36267 414 Pfam PF00155 Aminotransferase class I and II 66 394 3.1E-37 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS26500 2973eee7104695eafacc7fbc69c36267 414 SUPERFAMILY SSF53383 7 400 6.12E-91 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS26500 2973eee7104695eafacc7fbc69c36267 414 Gene3D G3DSA:3.40.640.10 64 284 1.1E-67 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS26500 2973eee7104695eafacc7fbc69c36267 414 Gene3D G3DSA:3.90.1150.10 285 401 1.2E-10 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS13950 4e822024fdf7899193232e5e95fe381b 334 SUPERFAMILY SSF53850 118 296 9.15E-16 T 06-07-2017 CAL12_RS13950 4e822024fdf7899193232e5e95fe381b 334 PIRSF PIRSF017082 1 334 2.2E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13950 4e822024fdf7899193232e5e95fe381b 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 1.4E-95 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 Pfam PF01799 [2Fe-2S] binding domain 71 142 6.6E-22 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 61 2.2E-8 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 Gene3D G3DSA:1.10.150.120 73 149 2.2E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 SUPERFAMILY SSF54292 2 76 2.36E-25 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 SUPERFAMILY SSF47741 82 147 3.79E-25 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS21200 c6c6b9e1b83a2466671b91768fe5a381 156 Gene3D G3DSA:3.10.20.30 2 72 1.7E-29 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 27 43 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 86 107 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 63 84 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 126 146 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 4 26 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PRINTS PR01004 Flagellar FliJ protein signature 44 61 1.2E-11 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 9.2E-33 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 PIRSF PIRSF019404 1 147 5.3E-51 T 06-07-2017 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 CAL12_RS12005 9b90d2a9151f9ad373a94ddd4bde3d82 149 Pfam PF02050 Flagellar FliJ protein 19 141 2.1E-33 T 06-07-2017 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 CAL12_RS06495 c25154bfa1ed8bb5068beb0f459ecb69 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 252 7.8E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06495 c25154bfa1ed8bb5068beb0f459ecb69 264 Gene3D G3DSA:1.10.3720.10 57 253 9.7E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06495 c25154bfa1ed8bb5068beb0f459ecb69 264 SUPERFAMILY SSF161098 57 241 3.14E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25930 e30f263303a3dc4c48ed2c58d54d576e 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 280 7.3E-41 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS25930 e30f263303a3dc4c48ed2c58d54d576e 315 Gene3D G3DSA:3.40.50.720 100 281 1.7E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25930 e30f263303a3dc4c48ed2c58d54d576e 315 SUPERFAMILY SSF51735 101 281 1.23E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 SUPERFAMILY SSF64518 1 549 5.23E-105 T 06-07-2017 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 2.2E-44 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 PRINTS PR00207 Flagellin signature 76 95 7.1E-32 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 PRINTS PR00207 Flagellin signature 37 54 7.1E-32 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 PRINTS PR00207 Flagellin signature 111 134 7.1E-32 T 06-07-2017 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 Gene3D G3DSA:1.20.1330.10 451 505 1.3E-57 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 Gene3D G3DSA:1.20.1330.10 55 170 1.3E-57 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS11790 b3512fdc5afa6cbf651392260f0ea043 549 Pfam PF00700 Bacterial flagellin C-terminal helical region 463 548 1.8E-31 T 06-07-2017 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 185 302 1.4E-21 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 Gene3D G3DSA:3.40.50.720 1 186 6.3E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 SMART SM01350 185 324 1.3E-5 T 06-07-2017 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 SUPERFAMILY SSF48179 183 317 2.38E-39 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 1 325 4.7E-119 T 06-07-2017 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 SUPERFAMILY SSF51735 1 160 3.39E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 153 7.4E-42 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 258 285 1.8E-17 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 19 1.8E-17 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 174 202 1.8E-17 T 06-07-2017 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CAL12_RS22845 af9f356f9af21349d41f5776ed45df5b 325 Gene3D G3DSA:1.10.1040.10 187 303 8.0E-35 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 260 6.3E-63 T 06-07-2017 CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 Gene3D G3DSA:3.40.50.720 3 263 8.9E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 5.3E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 SUPERFAMILY SSF51735 6 262 9.19E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05940 611a4a82a95df524baf9e826438bb226 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 8.2E-30 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06925 a7fbed316dd228318d85a6ab539c16b0 239 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 17 218 1.6E-56 T 06-07-2017 IPR026336 Metallophosphoesterase, DNA ligase-associated CAL12_RS06925 a7fbed316dd228318d85a6ab539c16b0 239 SUPERFAMILY SSF56300 39 172 4.46E-12 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS06925 a7fbed316dd228318d85a6ab539c16b0 239 Pfam PF00149 Calcineurin-like phosphoesterase 39 128 1.1E-4 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS06925 a7fbed316dd228318d85a6ab539c16b0 239 Gene3D G3DSA:3.60.21.10 37 167 8.9E-10 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Pfam PF08238 Sel1 repeat 116 149 2.2E-8 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Pfam PF08238 Sel1 repeat 42 76 5.6E-7 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Pfam PF08238 Sel1 repeat 79 111 1.0E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Pfam PF08238 Sel1 repeat 190 211 240.0 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Pfam PF08238 Sel1 repeat 157 185 0.027 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 SMART SM00671 115 149 1.9E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 SMART SM00671 41 76 1.4E-7 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 SMART SM00671 77 112 8.2E-5 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 SMART SM00671 150 185 0.04 T 06-07-2017 IPR006597 Sel1-like repeat CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 Gene3D G3DSA:1.25.40.10 30 215 2.1E-45 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS26775 15e404029e9d3f7a7dc6708fcea4c166 247 SUPERFAMILY SSF81901 26 212 8.72E-42 T 06-07-2017 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 PRINTS PR00045 Sigma-54 factor signature 475 493 1.5E-24 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 PRINTS PR00045 Sigma-54 factor signature 401 413 1.5E-24 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 PRINTS PR00045 Sigma-54 factor signature 212 229 1.5E-24 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 PRINTS PR00045 Sigma-54 factor signature 417 428 1.5E-24 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 17 60 7.7E-15 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 Pfam PF04552 Sigma-54, DNA binding domain 344 500 4.6E-60 T 06-07-2017 IPR007634 RNA polymerase sigma factor 54, DNA-binding CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 PIRSF PIRSF000774 11 501 2.4E-141 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 Pfam PF04963 Sigma-54 factor, core binding domain 137 329 1.1E-49 T 06-07-2017 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 389 408 - T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS17650 56988b13e88cd9d8475c95b5850e4e06 501 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 21 499 3.5E-135 T 06-07-2017 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 SUPERFAMILY SSF53067 5 80 1.67E-9 T 06-07-2017 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 SUPERFAMILY SSF53067 262 346 1.67E-9 T 06-07-2017 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 SUPERFAMILY SSF53067 397 492 1.67E-9 T 06-07-2017 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 Pfam PF01968 Hydantoinase/oxoprolinase 204 499 5.3E-85 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 Gene3D G3DSA:3.30.420.40 2 54 8.8E-4 T 06-07-2017 CAL12_RS11255 ba71bd4630a30abe8076feee65d2105f 702 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 182 2.4E-51 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 261 431 6.3E-16 T 06-07-2017 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 397 - T 06-07-2017 IPR030390 RNA methyltransferase TrmA, active site CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 Gene3D G3DSA:2.40.50.140 5 73 8.9E-26 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 429 4.1E-90 T 06-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 Gene3D G3DSA:3.40.50.150 250 435 1.0E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 419 429 - T 06-07-2017 IPR030391 RNA methyltransferase TrmA, conserved site CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 4 437 69.032 T 06-07-2017 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 SUPERFAMILY SSF53335 62 435 3.61E-78 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15955 303be6af87d08692b1eac9265e751e54 466 SUPERFAMILY SSF50249 4 59 5.71E-12 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS05245 632be6f88a97b9794117f7ddb8d24fd0 246 Pfam PF00005 ABC transporter 30 174 2.2E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05245 632be6f88a97b9794117f7ddb8d24fd0 246 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05245 632be6f88a97b9794117f7ddb8d24fd0 246 Gene3D G3DSA:3.40.50.300 14 240 3.4E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05245 632be6f88a97b9794117f7ddb8d24fd0 246 SUPERFAMILY SSF52540 15 243 3.88E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05245 632be6f88a97b9794117f7ddb8d24fd0 246 SMART SM00382 39 224 5.6E-10 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26520 9868f932e643eefe7951ec774e519a32 629 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 216 624 1.4E-94 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS26520 9868f932e643eefe7951ec774e519a32 629 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 50 174 3.1E-27 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS26520 9868f932e643eefe7951ec774e519a32 629 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 225 626 2.4E-85 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 06-07-2017 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 Pfam PF01144 Coenzyme A transferase 7 205 5.7E-39 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 Gene3D G3DSA:3.40.810.20 3 214 2.0E-90 T 06-07-2017 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 SUPERFAMILY SSF100950 3 214 3.84E-70 T 06-07-2017 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 SMART SM00882 6 206 1.4E-79 T 06-07-2017 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 CAL12_RS08580 7f78023872ab8dec1a292516f6957ad5 220 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 4.1E-95 T 06-07-2017 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 5.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 5.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 5.3E-6 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 Gene3D G3DSA:1.10.10.10 17 155 3.2E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 SUPERFAMILY SSF46785 18 155 1.81E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 SMART SM00347 40 140 9.1E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 06-07-2017 IPR023187 Transcriptional regulator MarR-type, conserved site CAL12_RS09085 047993d4e38572e143e6c50a9e9d95a0 187 Pfam PF01047 MarR family 47 105 3.4E-17 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 Gene3D G3DSA:3.90.550.10 8 275 3.7E-94 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 SUPERFAMILY SSF51182 189 473 6.12E-87 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 Pfam PF01050 Mannose-6-phosphate isomerase 319 469 3.7E-72 T 06-07-2017 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 Gene3D G3DSA:2.60.120.10 362 473 9.5E-47 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 9 473 4.7E-208 T 06-07-2017 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 Pfam PF00483 Nucleotidyl transferase 10 290 1.3E-64 T 06-07-2017 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CAL12_RS08000 627948ea83ba8565d6985fe62eba8e3c 474 SUPERFAMILY SSF53448 9 284 1.22E-71 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS16450 b77f38a583c1247921b9487ffb3ab7b1 134 Gene3D G3DSA:3.30.1330.40 2 129 2.5E-40 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS16450 b77f38a583c1247921b9487ffb3ab7b1 134 Pfam PF01042 Endoribonuclease L-PSP 13 127 9.4E-27 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS16450 b77f38a583c1247921b9487ffb3ab7b1 134 SUPERFAMILY SSF55298 10 129 3.93E-35 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS25740 a35fcce54435c0813ae5fe991a603c29 260 SUPERFAMILY SSF161098 61 244 6.15E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25740 a35fcce54435c0813ae5fe991a603c29 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 242 1.6E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25740 a35fcce54435c0813ae5fe991a603c29 260 Gene3D G3DSA:1.10.3720.10 57 244 2.5E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 Gene3D G3DSA:3.40.50.720 9 243 8.1E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 Pfam PF00106 short chain dehydrogenase 11 203 1.4E-51 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 SUPERFAMILY SSF51735 9 240 1.58E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 6.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 150 6.2E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 7.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 7.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS15425 63c0162137c9afaec876977c3ed749b8 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 7.7E-22 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS24115 26bdaeaa9d395d81380c1bda2a7140ec 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 210 2.9E-7 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS22815 ddb1fcf24571e9190f69d265fd2ce4d1 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 2.9E-94 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22815 ddb1fcf24571e9190f69d265fd2ce4d1 330 PIRSF PIRSF017082 2 330 1.4E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22815 ddb1fcf24571e9190f69d265fd2ce4d1 330 SUPERFAMILY SSF53850 120 286 5.67E-16 T 06-07-2017 CAL12_RS02785 eec56913915e328ab97a56ae0d679787 189 SUPERFAMILY SSF89392 28 187 1.06E-29 T 06-07-2017 IPR029046 Lipoprotein localisation LolA/LolB/LppX CAL12_RS02785 eec56913915e328ab97a56ae0d679787 189 Gene3D G3DSA:2.50.20.10 12 186 4.5E-33 T 06-07-2017 CAL12_RS02785 eec56913915e328ab97a56ae0d679787 189 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 50 165 8.6E-20 T 06-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CAL12_RS02785 eec56913915e328ab97a56ae0d679787 189 Pfam PF03550 Outer membrane lipoprotein LolB 33 187 2.7E-34 T 06-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CAL12_RS02785 eec56913915e328ab97a56ae0d679787 189 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 2 189 19.834 T 06-07-2017 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 CAL12_RS20545 352692abe93f4d4a8756f83adc0ce56d 489 Gene3D G3DSA:1.20.1600.10 56 480 2.3E-99 T 06-07-2017 CAL12_RS20545 352692abe93f4d4a8756f83adc0ce56d 489 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 17 477 4.1E-100 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS20545 352692abe93f4d4a8756f83adc0ce56d 489 Pfam PF02321 Outer membrane efflux protein 72 266 2.0E-27 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS20545 352692abe93f4d4a8756f83adc0ce56d 489 Pfam PF02321 Outer membrane efflux protein 298 466 7.6E-26 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS20545 352692abe93f4d4a8756f83adc0ce56d 489 SUPERFAMILY SSF56954 10 480 3.27E-103 T 06-07-2017 CAL12_RS26885 3918169412b4b0301122d5b65e7310d7 432 Pfam PF00534 Glycosyl transferases group 1 304 404 1.2E-6 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS26885 3918169412b4b0301122d5b65e7310d7 432 Gene3D G3DSA:3.40.50.2000 237 404 4.8E-7 T 06-07-2017 CAL12_RS26885 3918169412b4b0301122d5b65e7310d7 432 SUPERFAMILY SSF53756 55 426 3.14E-15 T 06-07-2017 CAL12_RS26885 3918169412b4b0301122d5b65e7310d7 432 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 39 216 4.5E-54 T 06-07-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 CAL12_RS07570 9ba69924414f78b263329fbbe4a3a408 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 4.9E-101 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07570 9ba69924414f78b263329fbbe4a3a408 328 SUPERFAMILY SSF53850 115 292 2.99E-16 T 06-07-2017 CAL12_RS07570 9ba69924414f78b263329fbbe4a3a408 328 PIRSF PIRSF017082 1 328 5.6E-95 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23730 f1e04d5ef2fd6b3d62f62d23e5601542 179 Gene3D G3DSA:2.40.50.180 55 88 4.3E-8 T 06-07-2017 CAL12_RS23730 f1e04d5ef2fd6b3d62f62d23e5601542 179 SUPERFAMILY SSF50341 14 155 7.19E-37 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS23730 f1e04d5ef2fd6b3d62f62d23e5601542 179 Pfam PF01584 CheW-like domain 17 151 2.7E-35 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS23730 f1e04d5ef2fd6b3d62f62d23e5601542 179 Gene3D G3DSA:2.30.30.40 89 149 5.8E-6 T 06-07-2017 CAL12_RS23730 f1e04d5ef2fd6b3d62f62d23e5601542 179 SMART SM00260 13 155 4.7E-34 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS11130 fa61488e778c1d4c19c687f2b29b4731 632 SUPERFAMILY SSF101898 308 405 2.3E-10 T 06-07-2017 CAL12_RS11130 fa61488e778c1d4c19c687f2b29b4731 632 SUPERFAMILY SSF101898 527 600 2.3E-10 T 06-07-2017 CAL12_RS11130 fa61488e778c1d4c19c687f2b29b4731 632 SUPERFAMILY SSF101898 437 498 2.3E-10 T 06-07-2017 CAL12_RS11130 fa61488e778c1d4c19c687f2b29b4731 632 Gene3D G3DSA:2.120.10.30 308 601 4.2E-8 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS11130 fa61488e778c1d4c19c687f2b29b4731 632 Pfam PF05787 Bacterial protein of unknown function (DUF839) 108 604 2.7E-138 T 06-07-2017 IPR008557 Protein of unknown function DUF839 CAL12_RS22585 e8ca5f64d71a5d3db1781b7eff4c43a8 308 Gene3D G3DSA:3.40.50.720 47 108 3.8E-4 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22585 e8ca5f64d71a5d3db1781b7eff4c43a8 308 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 101 273 3.8E-49 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS22585 e8ca5f64d71a5d3db1781b7eff4c43a8 308 SUPERFAMILY SSF52283 38 122 5.1E-7 T 06-07-2017 CAL12_RS22585 e8ca5f64d71a5d3db1781b7eff4c43a8 308 SUPERFAMILY SSF51735 94 274 5.14E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22585 e8ca5f64d71a5d3db1781b7eff4c43a8 308 Gene3D G3DSA:3.40.50.720 109 274 8.4E-55 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16105 81a0ae178ff0e76bcdd5c4d47a3b3659 343 SUPERFAMILY SSF53850 132 305 1.28E-14 T 06-07-2017 CAL12_RS16105 81a0ae178ff0e76bcdd5c4d47a3b3659 343 Gene3D G3DSA:3.40.190.10 147 245 7.6E-5 T 06-07-2017 CAL12_RS16105 81a0ae178ff0e76bcdd5c4d47a3b3659 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 339 8.8E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16105 81a0ae178ff0e76bcdd5c4d47a3b3659 343 PIRSF PIRSF017082 16 342 1.9E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 Gene3D G3DSA:3.40.192.10 15 119 9.3E-34 T 06-07-2017 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 19 102 4.4E-21 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 SUPERFAMILY SSF53223 14 114 2.01E-28 T 06-07-2017 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 Gene3D G3DSA:3.40.50.720 120 290 1.9E-44 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 SUPERFAMILY SSF51735 115 289 1.12E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 17 290 2.6E-71 T 06-07-2017 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 14 289 31.23 T 06-07-2017 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAL12_RS24930 59c22618456cd59b70e68986c8415599 296 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 129 177 8.6E-9 T 06-07-2017 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CAL12_RS12550 162e43589706dfc5ece0b2b5429ce714 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 236 255 - T 06-07-2017 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CAL12_RS12550 162e43589706dfc5ece0b2b5429ce714 351 Gene3D G3DSA:3.40.718.10 2 350 3.1E-105 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS12550 162e43589706dfc5ece0b2b5429ce714 351 SMART SM01329 2 346 7.8E-140 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS12550 162e43589706dfc5ece0b2b5429ce714 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 341 2.5E-89 T 06-07-2017 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CAL12_RS12550 162e43589706dfc5ece0b2b5429ce714 351 SUPERFAMILY SSF53659 1 350 1.29E-106 T 06-07-2017 CAL12_RS07490 c114278efbbabdd7f67a3ec2d1519356 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 120 7.3E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS07490 c114278efbbabdd7f67a3ec2d1519356 231 SUPERFAMILY SSF161098 17 211 1.96E-37 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07490 c114278efbbabdd7f67a3ec2d1519356 231 Gene3D G3DSA:1.10.3720.10 17 225 1.6E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07490 c114278efbbabdd7f67a3ec2d1519356 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 224 2.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 SUPERFAMILY SSF46785 16 87 2.32E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 SMART SM00345 25 83 1.5E-9 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 SMART SM00895 93 217 1.2E-12 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 Gene3D G3DSA:1.20.120.530 88 227 3.1E-25 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 SUPERFAMILY SSF48008 89 223 1.31E-22 T 06-07-2017 IPR008920 Transcription regulator FadR/GntR, C-terminal CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 Pfam PF07729 FCD domain 94 213 8.4E-22 T 06-07-2017 IPR011711 GntR, C-terminal CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 Gene3D G3DSA:1.10.10.10 9 83 3.4E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 3.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 3.9E-5 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS23445 cbb21bab653e0301a5fb6f18fd16652e 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 78 4.1E-13 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS17750 630d7d1484535ed1902aaa67180abc0a 115 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 1.4E-35 T 06-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS04390 7d9c44ab3270fd4b1414e70ecae8cc30 170 Pfam PF13801 Heavy-metal resistance 12 137 7.9E-31 T 06-07-2017 IPR025961 Heavy-metal resistance protein CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.537 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.7E-35 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 Gene3D G3DSA:1.10.1200.10 3 76 3.8E-35 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 5.0E-4 T 06-07-2017 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 06-07-2017 IPR006162 Phosphopantetheine attachment site CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.5E-17 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS08370 d55f157600a99bdac5d796bbf49b031c 79 SUPERFAMILY SSF47336 2 76 9.16E-24 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 25 395 9.3E-84 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 311 330 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 104 130 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 132 151 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 371 390 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 157 178 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 209 232 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 PRINTS PR00447 Natural resistance-associated macrophage protein signature 339 356 3.0E-41 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS17335 c5c7433b61aecfb5982eb2f42d66f460 430 Pfam PF01566 Natural resistance-associated macrophage protein 45 400 5.9E-99 T 06-07-2017 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CAL12_RS13980 265d87423370f3b1e7aad734edc69978 222 Gene3D G3DSA:3.50.30.40 33 183 1.6E-44 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS13980 265d87423370f3b1e7aad734edc69978 222 SUPERFAMILY SSF89562 24 185 9.94E-42 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS13980 265d87423370f3b1e7aad734edc69978 222 Pfam PF03737 Demethylmenaquinone methyltransferase 41 174 4.5E-34 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS23005 aa4756a291e725dd5c90e6881b341e2c 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 12 308 3.6E-56 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23005 aa4756a291e725dd5c90e6881b341e2c 332 Gene3D G3DSA:3.90.25.10 177 317 1.8E-51 T 06-07-2017 CAL12_RS23005 aa4756a291e725dd5c90e6881b341e2c 332 SUPERFAMILY SSF51735 6 316 2.88E-90 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23005 aa4756a291e725dd5c90e6881b341e2c 332 Gene3D G3DSA:3.40.50.720 7 176 1.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25295 481c4195915149631f305fbe4fa074dc 168 PIRSF PIRSF018472 3 161 1.1E-32 T 06-07-2017 IPR026034 Cell shape-determining protein MreD, proteobacterial type CAL12_RS25295 481c4195915149631f305fbe4fa074dc 168 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 12 153 2.5E-22 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CAL12_RS25295 481c4195915149631f305fbe4fa074dc 168 Pfam PF04093 rod shape-determining protein MreD 15 148 1.8E-12 T 06-07-2017 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 ProSitePatterns PS00455 Putative AMP-binding domain signature. 144 155 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 Gene3D G3DSA:3.30.300.30 384 478 1.3E-4 T 06-07-2017 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 Gene3D G3DSA:3.40.50.980 151 317 5.7E-21 T 06-07-2017 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 SUPERFAMILY SSF56801 18 482 2.88E-80 T 06-07-2017 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 Pfam PF00501 AMP-binding enzyme 13 382 7.4E-48 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 Gene3D G3DSA:3.40.50.980 18 150 7.9E-21 T 06-07-2017 CAL12_RS14240 fdf3f9ecc7651a13752f5a05200af2c0 493 Gene3D G3DSA:2.30.38.10 332 376 1.1E-4 T 06-07-2017 CAL12_RS20635 968eef17725334573541645d64ffc1a9 331 Pfam PF00795 Carbon-nitrogen hydrolase 6 293 1.6E-49 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS20635 968eef17725334573541645d64ffc1a9 331 SUPERFAMILY SSF56317 3 316 4.19E-71 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS20635 968eef17725334573541645d64ffc1a9 331 Gene3D G3DSA:3.60.110.10 3 316 8.5E-74 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS03890 e662d1b9b782922158bc633a55d200e4 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 77 253 5.4E-6 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03890 e662d1b9b782922158bc633a55d200e4 260 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 259 5.6E-115 T 06-07-2017 IPR012690 2-oxo-hepta-3-ene-1,7-dioic acid hydratase GO:0019439 CAL12_RS03890 e662d1b9b782922158bc633a55d200e4 260 Gene3D G3DSA:3.90.850.10 1 259 3.8E-83 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03890 e662d1b9b782922158bc633a55d200e4 260 SUPERFAMILY SSF56529 3 259 1.7E-75 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS00475 98aaffc9d5e6afcfa32de5b532ff9000 379 SUPERFAMILY SSF51419 31 265 1.6E-40 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS00475 98aaffc9d5e6afcfa32de5b532ff9000 379 Gene3D G3DSA:3.20.20.10 33 197 7.6E-22 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS00475 98aaffc9d5e6afcfa32de5b532ff9000 379 SMART SM01119 274 362 1.2E-31 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS00475 98aaffc9d5e6afcfa32de5b532ff9000 379 Pfam PF01168 Alanine racemase, N-terminal domain 31 256 1.1E-32 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS00475 98aaffc9d5e6afcfa32de5b532ff9000 379 Pfam PF14031 Putative serine dehydratase domain 274 359 4.1E-19 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 Pfam PF02548 Ketopantoate hydroxymethyltransferase 16 275 1.3E-106 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 15 280 7.8E-92 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 SUPERFAMILY SSF51621 16 280 1.73E-99 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 PIRSF PIRSF000388 6 280 7.2E-98 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 16 280 40.869 T 06-07-2017 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CAL12_RS27120 5227b532c59d202d6fd1d48d163c9585 280 Gene3D G3DSA:3.20.20.60 14 280 6.9E-108 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 Gene3D G3DSA:3.40.190.10 180 258 4.8E-26 T 06-07-2017 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 Pfam PF03466 LysR substrate binding domain 90 291 8.3E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.5E-10 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 SUPERFAMILY SSF53850 88 291 1.57E-35 T 06-07-2017 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 Gene3D G3DSA:3.40.190.10 95 179 5.2E-24 T 06-07-2017 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 Gene3D G3DSA:1.10.10.10 6 85 1.4E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06090 63574ecb39bdcf12ad16ca826300212f 302 SUPERFAMILY SSF46785 6 115 5.01E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16625 bc3fd24b9cd98fb70f24037e1cb8f46a 256 SUPERFAMILY SSF52096 18 233 2.88E-41 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16625 bc3fd24b9cd98fb70f24037e1cb8f46a 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 227 2.9E-25 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS16625 bc3fd24b9cd98fb70f24037e1cb8f46a 256 Gene3D G3DSA:3.90.226.10 9 245 7.0E-47 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 Gene3D G3DSA:1.10.10.10 7 83 4.0E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 Gene3D G3DSA:3.40.190.10 93 184 3.0E-21 T 06-07-2017 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 Gene3D G3DSA:3.40.190.10 185 260 9.9E-8 T 06-07-2017 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 7.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 7.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 7.8E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 3.1E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 SUPERFAMILY SSF46785 8 116 4.42E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 Pfam PF03466 LysR substrate binding domain 93 291 2.4E-32 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS24810 e3319eaa159aec2c95d98caeb6d52d7c 298 SUPERFAMILY SSF53850 95 293 2.31E-34 T 06-07-2017 CAL12_RS23900 c86f65b678f4ac12b411948833b5c20f 308 Gene3D G3DSA:3.40.50.1820 63 300 6.5E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23900 c86f65b678f4ac12b411948833b5c20f 308 Pfam PF01738 Dienelactone hydrolase family 74 300 2.4E-60 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAL12_RS23900 c86f65b678f4ac12b411948833b5c20f 308 SUPERFAMILY SSF53474 63 300 4.42E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12310 3b130bab3e6711c1421b91ebba8d91d0 328 SUPERFAMILY SSF53850 115 287 4.81E-15 T 06-07-2017 CAL12_RS12310 3b130bab3e6711c1421b91ebba8d91d0 328 PIRSF PIRSF017082 1 326 2.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12310 3b130bab3e6711c1421b91ebba8d91d0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.0E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12710 dde7096147ed0afc150c17aca846101c 174 Gene3D G3DSA:3.30.450.40 29 143 1.1E-4 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS12710 dde7096147ed0afc150c17aca846101c 174 SUPERFAMILY SSF55781 35 148 3.09E-7 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS19160 6b5c338b3d655747af5a84f51b0fc176 186 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 11 117 1.7E-45 T 06-07-2017 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 CAL12_RS19160 6b5c338b3d655747af5a84f51b0fc176 186 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 12 70 7.5E-31 T 06-07-2017 IPR012909 PHA accumulation regulator DNA-binding, N-terminal CAL12_RS19160 6b5c338b3d655747af5a84f51b0fc176 186 Pfam PF05233 PHB accumulation regulatory domain 126 165 1.8E-15 T 06-07-2017 IPR007897 PHB accumulation regulatory CAL12_RS19160 6b5c338b3d655747af5a84f51b0fc176 186 Pfam PF05233 PHB accumulation regulatory domain 76 114 1.0E-19 T 06-07-2017 IPR007897 PHB accumulation regulatory CAL12_RS12390 30d9f8b62b232f05bfa62146f85f9c41 286 SUPERFAMILY SSF53850 47 286 1.52E-54 T 06-07-2017 CAL12_RS12390 30d9f8b62b232f05bfa62146f85f9c41 286 Gene3D G3DSA:3.40.190.10 45 174 1.8E-38 T 06-07-2017 CAL12_RS12390 30d9f8b62b232f05bfa62146f85f9c41 286 Pfam PF03180 NLPA lipoprotein 47 278 7.9E-56 T 06-07-2017 IPR004872 Lipoprotein NlpA family CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 SUPERFAMILY SSF111369 209 342 3.99E-16 T 06-07-2017 CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 SUPERFAMILY SSF111369 104 198 2.75E-11 T 06-07-2017 CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 99 349 2.6E-15 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 Pfam PF00529 HlyD membrane-fusion protein of T1SS 79 396 6.9E-11 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 Gene3D G3DSA:2.40.50.100 274 308 5.0E-19 T 06-07-2017 CAL12_RS04250 ac3951c924f9c18ac12d20507820c8a1 405 Gene3D G3DSA:2.40.50.100 104 137 5.0E-19 T 06-07-2017 CAL12_RS12100 aa08f6c0a680a8861cec9e9f792d9b5c 238 Pfam PF01914 MarC family integral membrane protein 14 220 5.7E-37 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAL12_RS12100 aa08f6c0a680a8861cec9e9f792d9b5c 238 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 14 217 1.4E-33 T 06-07-2017 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 Gene3D G3DSA:3.40.190.10 178 260 3.3E-23 T 06-07-2017 CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 Gene3D G3DSA:3.40.190.10 92 177 3.7E-23 T 06-07-2017 CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 9.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 Gene3D G3DSA:1.10.10.10 5 87 2.2E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 Pfam PF03466 LysR substrate binding domain 88 296 1.4E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 SUPERFAMILY SSF53850 90 298 1.27E-40 T 06-07-2017 CAL12_RS20695 0c5fcdc0708f59772ff5aeb76630d100 308 SUPERFAMILY SSF46785 6 112 6.74E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26125 8558337f5c52407968539c4edeed9ad3 172 Gene3D G3DSA:3.10.129.10 8 153 3.8E-54 T 06-07-2017 IPR029069 HotDog domain CAL12_RS26125 8558337f5c52407968539c4edeed9ad3 172 SUPERFAMILY SSF54637 8 151 2.59E-44 T 06-07-2017 IPR029069 HotDog domain CAL12_RS26125 8558337f5c52407968539c4edeed9ad3 172 Pfam PF03061 Thioesterase superfamily 24 98 5.5E-18 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS09560 e66f7e394f7fe62744c876825992a0cf 494 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 7 52 2.1E-5 T 06-07-2017 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 SUPERFAMILY SSF46785 39 144 3.63E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 74 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 74 85 4.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 SUPERFAMILY SSF53850 125 330 1.74E-30 T 06-07-2017 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 Gene3D G3DSA:3.40.190.10 211 296 9.7E-13 T 06-07-2017 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 Gene3D G3DSA:1.10.10.10 40 122 3.4E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 Pfam PF03466 LysR substrate binding domain 124 328 6.0E-28 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 40 96 8.0E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03210 8e81aa049e3ea482d29c53f0fe15d3de 351 Gene3D G3DSA:3.40.190.10 125 210 1.6E-13 T 06-07-2017 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 SUPERFAMILY SSF100950 77 235 7.33E-12 T 06-07-2017 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 SUPERFAMILY SSF46785 4 59 4.57E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 SMART SM00420 6 58 1.1E-15 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 Gene3D G3DSA:3.30.750.70 76 123 5.1E-4 T 06-07-2017 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 SMART SM01134 70 236 4.2E-23 T 06-07-2017 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 Gene3D G3DSA:1.10.10.10 1 59 5.3E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.3E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.3E-8 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 06-07-2017 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.1E-15 T 06-07-2017 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CAL12_RS27825 952d9c5d2e9a960564fa0dcd5ea0edca 256 Pfam PF00455 DeoR C terminal sensor domain 77 234 4.3E-27 T 06-07-2017 IPR014036 DeoR C-terminal sensor domain CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.3E-33 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 SUPERFAMILY SSF51735 2 258 1.41E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 Gene3D G3DSA:3.40.50.720 1 257 5.8E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 2.1E-50 T 06-07-2017 CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06740 b491945ea58966597ee99a404cfcd836 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.4E-10 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07310 39f45a6c1d1eaa49b21cd053829934da 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 269 1.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07310 39f45a6c1d1eaa49b21cd053829934da 281 Gene3D G3DSA:1.10.3720.10 72 268 1.3E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07310 39f45a6c1d1eaa49b21cd053829934da 281 SUPERFAMILY SSF161098 75 261 2.88E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06440 4bd0e537ad7635a9308dd8d8fb3042df 213 Gene3D G3DSA:1.10.3210.10 28 139 1.5E-11 T 06-07-2017 IPR006674 HD domain CAL12_RS06440 4bd0e537ad7635a9308dd8d8fb3042df 213 Pfam PF01966 HD domain 32 117 1.8E-10 T 06-07-2017 IPR006674 HD domain CAL12_RS06440 4bd0e537ad7635a9308dd8d8fb3042df 213 SUPERFAMILY SSF109604 25 157 2.86E-17 T 06-07-2017 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 SUPERFAMILY SSF46785 3 87 2.45E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 Pfam PF03466 LysR substrate binding domain 88 295 1.1E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 Gene3D G3DSA:1.10.10.10 4 84 1.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 Gene3D G3DSA:3.40.190.10 178 268 1.2E-26 T 06-07-2017 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.2E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 Gene3D G3DSA:3.40.190.10 89 177 3.0E-30 T 06-07-2017 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.1E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20835 2321123f4669a48603ff14e2df83f79f 301 SUPERFAMILY SSF53850 88 297 2.17E-36 T 06-07-2017 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 SUPERFAMILY SSF52210 135 295 2.88E-40 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Pfam PF13380 CoA binding domain 13 138 8.5E-25 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Gene3D G3DSA:3.30.470.20 519 631 1.6E-6 T 06-07-2017 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 SMART SM00881 9 104 3.3E-30 T 06-07-2017 IPR003781 CoA-binding GO:0048037 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Gene3D G3DSA:3.40.50.261 134 295 7.6E-28 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 SUPERFAMILY SSF52210 303 454 3.09E-20 T 06-07-2017 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 SUPERFAMILY SSF51735 3 140 5.52E-36 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 295 3.1E-49 T 06-07-2017 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Gene3D G3DSA:3.40.50.720 5 133 3.9E-39 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 Pfam PF13549 ATP-grasp domain 514 725 2.2E-62 T 06-07-2017 CAL12_RS04420 a63d182da71b7013d8ccee21b1289eb2 730 SUPERFAMILY SSF56059 514 726 3.14E-41 T 06-07-2017 CAL12_RS24845 24307404ba49b63862348ba90852e1ad 173 Pfam PF05433 Glycine zipper 2TM domain 82 121 6.4E-9 T 06-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 CAL12_RS25620 6ee6295e59c66c0ba6bfe5d7f2a8d482 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 131 6.0E-6 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS25620 6ee6295e59c66c0ba6bfe5d7f2a8d482 143 Gene3D G3DSA:3.10.180.10 10 138 2.7E-26 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS25620 6ee6295e59c66c0ba6bfe5d7f2a8d482 143 SUPERFAMILY SSF54593 7 133 4.7E-24 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS15525 a5b68437523789ee8346f2d0a7a64e8d 437 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 141 158 - T 06-07-2017 IPR006061 Solute-binding family 1, conserved site GO:0005215|GO:0006810 CAL12_RS15525 a5b68437523789ee8346f2d0a7a64e8d 437 SUPERFAMILY SSF53850 26 425 1.75E-82 T 06-07-2017 CAL12_RS15525 a5b68437523789ee8346f2d0a7a64e8d 437 Gene3D G3DSA:3.40.190.10 146 346 1.4E-43 T 06-07-2017 CAL12_RS15525 a5b68437523789ee8346f2d0a7a64e8d 437 Pfam PF13416 Bacterial extracellular solute-binding protein 44 356 2.0E-49 T 06-07-2017 CAL12_RS03665 7ac75a55025eadabb0ca5b80b252624c 340 Pfam PF09084 NMT1/THI5 like 55 265 1.6E-46 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS03665 7ac75a55025eadabb0ca5b80b252624c 340 Gene3D G3DSA:3.40.190.10 126 251 2.5E-9 T 06-07-2017 CAL12_RS03665 7ac75a55025eadabb0ca5b80b252624c 340 SUPERFAMILY SSF53850 42 272 1.33E-32 T 06-07-2017 CAL12_RS03665 7ac75a55025eadabb0ca5b80b252624c 340 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 32 1.4E-4 T 06-07-2017 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CAL12_RS21150 a8d13153998904054a7048adefd73198 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 109 8.1E-29 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS21150 a8d13153998904054a7048adefd73198 232 Gene3D G3DSA:1.10.3720.10 12 211 1.4E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21150 a8d13153998904054a7048adefd73198 232 SUPERFAMILY SSF161098 14 200 1.57E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21150 a8d13153998904054a7048adefd73198 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 213 1.7E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS18810 3abc83f47ae59e0cb0bb2e1439cfc678 236 Pfam PF03737 Demethylmenaquinone methyltransferase 42 187 7.1E-45 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS18810 3abc83f47ae59e0cb0bb2e1439cfc678 236 SUPERFAMILY SSF89562 37 198 1.83E-46 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS18810 3abc83f47ae59e0cb0bb2e1439cfc678 236 Gene3D G3DSA:3.50.30.40 37 196 1.0E-49 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS07530 03a609c82e568070f218505612ce4c7b 453 SUPERFAMILY SSF103473 224 433 1.57E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS07530 03a609c82e568070f218505612ce4c7b 453 SUPERFAMILY SSF103473 1 174 1.57E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS07530 03a609c82e568070f218505612ce4c7b 453 Pfam PF07690 Major Facilitator Superfamily 3 385 8.1E-48 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS07530 03a609c82e568070f218505612ce4c7b 453 Gene3D G3DSA:1.20.1250.20 3 168 7.5E-28 T 06-07-2017 CAL12_RS07530 03a609c82e568070f218505612ce4c7b 453 Gene3D G3DSA:1.20.1250.20 237 426 6.1E-14 T 06-07-2017 CAL12_RS03415 9ab9d5fb05dc19a529f6cf1239302fc2 477 Pfam PF03972 MmgE/PrpD family 27 444 5.3E-85 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS03415 9ab9d5fb05dc19a529f6cf1239302fc2 477 Gene3D G3DSA:3.30.1330.120 272 399 1.0E-22 T 06-07-2017 CAL12_RS03415 9ab9d5fb05dc19a529f6cf1239302fc2 477 SUPERFAMILY SSF103378 22 451 1.1E-79 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS01085 1e9c4567fe38522f219bfb1d66f5644c 566 SUPERFAMILY SSF53927 391 448 4.85E-33 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS01085 1e9c4567fe38522f219bfb1d66f5644c 566 SUPERFAMILY SSF53927 265 346 4.85E-33 T 06-07-2017 IPR016193 Cytidine deaminase-like GO:0003824 CAL12_RS01085 1e9c4567fe38522f219bfb1d66f5644c 566 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 265 441 6.7E-21 T 06-07-2017 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 CAL12_RS01085 1e9c4567fe38522f219bfb1d66f5644c 566 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 395 430 - T 06-07-2017 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CAL12_RS01085 1e9c4567fe38522f219bfb1d66f5644c 566 Gene3D G3DSA:3.40.140.10 265 465 7.1E-38 T 06-07-2017 CAL12_RS25815 38ef85ec80c4fd879c2b48136e2d8139 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 4.2E-27 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAL12_RS25815 38ef85ec80c4fd879c2b48136e2d8139 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 2.7E-39 T 06-07-2017 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 CAL12_RS25815 38ef85ec80c4fd879c2b48136e2d8139 156 SUPERFAMILY SSF81573 67 121 5.62E-6 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAL12_RS25815 38ef85ec80c4fd879c2b48136e2d8139 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 11.416 T 06-07-2017 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CAL12_RS25815 38ef85ec80c4fd879c2b48136e2d8139 156 Gene3D G3DSA:1.20.5.620 67 121 1.0E-11 T 06-07-2017 IPR028987 F-type ATP synthase subunit B-like, membrane domain CAL12_RS14880 257b2d147cbfe635215977e58294fa82 109 TIGRFAM TIGR02229 caa3_sub_IV: caa(3)-type oxidase, subunit IV 17 97 3.9E-17 T 06-07-2017 IPR011743 Caa(3)-type oxidase, subunit IV CAL12_RS14880 257b2d147cbfe635215977e58294fa82 109 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 87 6.0E-8 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CAL12_RS25430 08d49069b5baaddcfeffdd7fea4d2b3f 406 Pfam PF13657 HipA N-terminal domain 19 111 2.0E-15 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS25430 08d49069b5baaddcfeffdd7fea4d2b3f 406 Pfam PF07805 HipA-like N-terminal domain 151 233 1.3E-14 T 06-07-2017 IPR012894 HipA, N-terminal subdomain 2 CAL12_RS25430 08d49069b5baaddcfeffdd7fea4d2b3f 406 Pfam PF07804 HipA-like C-terminal domain 242 379 7.7E-28 T 06-07-2017 IPR012893 HipA-like, C-terminal CAL12_RS25430 08d49069b5baaddcfeffdd7fea4d2b3f 406 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 18 111 8.1E-11 T 06-07-2017 IPR017508 HipA, N-terminal subdomain 1 CAL12_RS19535 1ca49d3649331323247f819f289792bf 225 SMART SM00382 26 206 6.9E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS19535 1ca49d3649331323247f819f289792bf 225 Pfam PF00005 ABC transporter 27 161 7.1E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS19535 1ca49d3649331323247f819f289792bf 225 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS19535 1ca49d3649331323247f819f289792bf 225 SUPERFAMILY SSF52540 2 217 4.77E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS19535 1ca49d3649331323247f819f289792bf 225 Gene3D G3DSA:3.40.50.300 2 217 3.7E-56 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 Pfam PF01494 FAD binding domain 5 338 6.8E-17 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.8E-16 T 06-07-2017 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.8E-16 T 06-07-2017 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.8E-16 T 06-07-2017 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.8E-16 T 06-07-2017 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 Gene3D G3DSA:3.50.50.60 5 174 1.6E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 Gene3D G3DSA:3.50.50.60 268 355 1.6E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 388 1.7E-95 T 06-07-2017 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 SUPERFAMILY SSF51905 1 169 4.26E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 SUPERFAMILY SSF51905 275 388 4.26E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS26080 815f6867f9f7f2fcba657e3ab624b4a1 389 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 06-07-2017 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 SUPERFAMILY SSF58104 200 470 1.83E-61 T 06-07-2017 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 283 468 9.2E-50 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 397 426 1.5E-41 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 349 378 1.5E-41 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 243 272 1.5E-41 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 320 347 1.5E-41 T 06-07-2017 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 SMART SM00283 222 469 1.8E-73 T 06-07-2017 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CAL12_RS04695 e205699ea37a39dd355dde6c49c1a060 508 Gene3D G3DSA:1.10.287.950 238 441 3.8E-51 T 06-07-2017 CAL12_RS02475 6e5e4225070ff41a9987010674f25cea 311 SUPERFAMILY SSF51197 8 293 1.92E-78 T 06-07-2017 CAL12_RS02475 6e5e4225070ff41a9987010674f25cea 311 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 286 9.1E-54 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS02475 6e5e4225070ff41a9987010674f25cea 311 Gene3D G3DSA:3.60.130.10 5 301 4.7E-81 T 06-07-2017 CAL12_RS07470 2be6b4cc9fb2fc36530c57e4d8799aeb 195 Gene3D G3DSA:2.60.120.10 52 189 1.1E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS07470 2be6b4cc9fb2fc36530c57e4d8799aeb 195 SUPERFAMILY SSF51182 11 190 4.11E-38 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS04120 25db162443610d24874eb15aae6b538f 73 Pfam PF13318 Protein of unknown function (DUF4089) 14 59 3.7E-9 T 06-07-2017 IPR025148 Protein of unknown function DUF4089 CAL12_RS05640 391d6c3f319d6b274e683747213d9f73 394 Pfam PF09663 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) 9 391 1.3E-150 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAL12_RS05640 391d6c3f319d6b274e683747213d9f73 394 TIGRFAM TIGR02714 amido_AtzD_TrzD: ring-opening amidohydrolases 9 391 2.5E-134 T 06-07-2017 IPR014086 Cyanuric acid hydrolase/Barbiturase GO:0016812 CAL12_RS04135 0fdf10a12cfe65d6bf5f53a9657bf7d3 338 SUPERFAMILY SSF53850 43 276 1.82E-33 T 06-07-2017 CAL12_RS04135 0fdf10a12cfe65d6bf5f53a9657bf7d3 338 Pfam PF09084 NMT1/THI5 like 56 275 1.2E-21 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS04135 0fdf10a12cfe65d6bf5f53a9657bf7d3 338 Gene3D G3DSA:3.40.190.10 134 260 1.8E-18 T 06-07-2017 CAL12_RS04760 e05e8754f7c7e83213fc0f048556e617 199 Gene3D G3DSA:3.90.280.10 31 194 9.0E-46 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS04760 e05e8754f7c7e83213fc0f048556e617 199 Pfam PF01161 Phosphatidylethanolamine-binding protein 61 190 5.6E-33 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS04760 e05e8754f7c7e83213fc0f048556e617 199 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 52 187 2.5E-34 T 06-07-2017 IPR005247 YbhB/YbcL CAL12_RS04760 e05e8754f7c7e83213fc0f048556e617 199 SUPERFAMILY SSF49777 53 192 8.37E-41 T 06-07-2017 IPR008914 Phosphatidylethanolamine-binding protein CAL12_RS27645 2bded527b12f4418f6b8fb9b9d43154d 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 21.829 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27645 2bded527b12f4418f6b8fb9b9d43154d 98 Pfam PF00276 Ribosomal protein L23 8 94 2.8E-29 T 06-07-2017 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CAL12_RS27645 2bded527b12f4418f6b8fb9b9d43154d 98 Gene3D G3DSA:3.30.70.330 5 96 3.6E-32 T 06-07-2017 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 CAL12_RS27645 2bded527b12f4418f6b8fb9b9d43154d 98 SUPERFAMILY SSF54189 1 92 4.68E-29 T 06-07-2017 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS14455 4f78907ac3197f54de48f19b274b6fad 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 278 1.4E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14455 4f78907ac3197f54de48f19b274b6fad 284 SUPERFAMILY SSF161098 10 274 2.52E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14455 4f78907ac3197f54de48f19b274b6fad 284 Gene3D G3DSA:1.10.3720.10 12 279 6.0E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06415 eb6f5c5bf2419f1b06c06ce9925af3d5 173 SUPERFAMILY SSF52540 36 144 8.68E-19 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06415 eb6f5c5bf2419f1b06c06ce9925af3d5 173 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 11 150 3.1E-36 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAL12_RS06415 eb6f5c5bf2419f1b06c06ce9925af3d5 173 Gene3D G3DSA:3.40.50.300 6 161 1.4E-45 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS06415 eb6f5c5bf2419f1b06c06ce9925af3d5 173 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 12 141 2.2E-34 T 06-07-2017 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 SMART SM00530 10 65 8.4E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 SUPERFAMILY SSF47413 2 71 7.51E-18 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 Pfam PF01381 Helix-turn-helix 11 63 5.9E-15 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 SUPERFAMILY SSF51182 51 186 9.62E-22 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 Gene3D G3DSA:2.60.120.10 77 186 8.7E-15 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS03520 53d8a09ecf21c974bec68f34ba59691a 190 Gene3D G3DSA:1.10.260.40 2 75 1.3E-22 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS07285 8b89fb332c3807a54e414d2ba0e8082b 198 SUPERFAMILY SSF52218 1 170 4.19E-29 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS07285 8b89fb332c3807a54e414d2ba0e8082b 198 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 4.4E-63 T 06-07-2017 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 CAL12_RS07285 8b89fb332c3807a54e414d2ba0e8082b 198 Pfam PF03358 NADPH-dependent FMN reductase 1 142 7.4E-26 T 06-07-2017 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CAL12_RS07285 8b89fb332c3807a54e414d2ba0e8082b 198 Gene3D G3DSA:3.40.50.360 1 174 7.0E-30 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS25015 fd86f5a71fc6da0a1a48e7cab938cfbb 266 SMART SM00267 90 261 7.1E-59 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25015 fd86f5a71fc6da0a1a48e7cab938cfbb 266 SUPERFAMILY SSF55073 106 260 2.12E-47 T 06-07-2017 IPR029787 Nucleotide cyclase CAL12_RS25015 fd86f5a71fc6da0a1a48e7cab938cfbb 266 Pfam PF00990 Diguanylate cyclase, GGDEF domain 102 257 5.5E-45 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25015 fd86f5a71fc6da0a1a48e7cab938cfbb 266 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 98 260 6.9E-47 T 06-07-2017 IPR000160 GGDEF domain CAL12_RS25015 fd86f5a71fc6da0a1a48e7cab938cfbb 266 Gene3D G3DSA:3.30.70.270 103 260 1.6E-53 T 06-07-2017 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 SUPERFAMILY SSF56194 220 346 1.96E-47 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Gene3D G3DSA:3.30.465.10 88 247 2.9E-50 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 343 9.6E-65 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 224 345 2.7E-35 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 SUPERFAMILY SSF56176 21 206 2.06E-35 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Gene3D G3DSA:3.90.78.10 248 345 8.6E-43 T 06-07-2017 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Gene3D G3DSA:3.30.43.10 21 82 1.6E-12 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 347 78.37 T 06-07-2017 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS06190 46beef9d7c0bfc84bb31ff1307ab49fd 347 Pfam PF01565 FAD binding domain 34 165 1.9E-18 T 06-07-2017 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CAL12_RS18085 ffe8512329216a9d9bf3bb91fc7558af 824 Pfam PF02687 FtsX-like permease family 254 338 7.6E-11 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS18085 ffe8512329216a9d9bf3bb91fc7558af 824 Pfam PF02687 FtsX-like permease family 703 816 1.7E-12 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS16330 bdc37c1d0698c89ff3743e628c5a4684 576 Gene3D G3DSA:3.40.190.10 203 443 3.1E-42 T 06-07-2017 CAL12_RS16330 bdc37c1d0698c89ff3743e628c5a4684 576 Gene3D G3DSA:3.40.190.10 80 202 1.3E-13 T 06-07-2017 CAL12_RS16330 bdc37c1d0698c89ff3743e628c5a4684 576 PIRSF PIRSF035859 1 575 0.0 T 06-07-2017 IPR014597 ABC transporter, periplasmic substrate-binding protein GO:0005215 CAL12_RS16330 bdc37c1d0698c89ff3743e628c5a4684 576 Pfam PF13416 Bacterial extracellular solute-binding protein 84 432 1.9E-11 T 06-07-2017 CAL12_RS16330 bdc37c1d0698c89ff3743e628c5a4684 576 SUPERFAMILY SSF53850 74 516 3.07E-63 T 06-07-2017 CAL12_RS22230 4941e2ca3fa17d79b3d5494bc3ac9a18 350 Pfam PF03601 Conserved hypothetical protein 698 20 330 7.2E-92 T 06-07-2017 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CAL12_RS22230 4941e2ca3fa17d79b3d5494bc3ac9a18 350 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 20 345 4.3E-83 T 06-07-2017 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Gene3D G3DSA:1.10.2060.10 136 253 5.7E-53 T 06-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Gene3D G3DSA:1.20.5.550 87 135 2.2E-21 T 06-07-2017 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 SUPERFAMILY SSF47598 3 45 1.38E-7 T 06-07-2017 IPR010985 Ribbon-helix-helix GO:0006355 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 606 1102 8.7E-235 T 06-07-2017 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Gene3D G3DSA:3.40.605.10 651 891 3.2E-66 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 141 252 1.8E-46 T 06-07-2017 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Pfam PF01619 Proline dehydrogenase 264 562 3.1E-98 T 06-07-2017 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 SUPERFAMILY SSF51730 255 605 1.33E-120 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Pfam PF00171 Aldehyde dehydrogenase family 652 1099 8.1E-115 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 904 915 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 PIRSF PIRSF000197 74 1270 0.0 T 06-07-2017 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 SUPERFAMILY SSF81935 87 253 1.96E-62 T 06-07-2017 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 SUPERFAMILY SSF53720 645 1102 2.23E-126 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Gene3D G3DSA:3.40.309.10 892 1079 1.9E-45 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS17365 dc0572e741ff32cbf9a805ad1d199984 1270 Gene3D G3DSA:3.20.20.220 255 603 1.5E-117 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAL12_RS08390 8f0298a1fdaf363e129ec7594c285dcf 172 SUPERFAMILY SSF89069 15 78 7.19E-12 T 06-07-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CAL12_RS08390 8f0298a1fdaf363e129ec7594c285dcf 172 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 17 87 2.4E-10 T 06-07-2017 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 CAL12_RS19470 574e814d44d03e79ca54f991c5979fab 360 SUPERFAMILY SSF53850 146 318 5.84E-14 T 06-07-2017 CAL12_RS19470 574e814d44d03e79ca54f991c5979fab 360 PIRSF PIRSF017082 23 355 1.5E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19470 574e814d44d03e79ca54f991c5979fab 360 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 80 349 1.6E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12595 f567313667c4bc78e1703a30e29c255e 342 PIRSF PIRSF017082 8 342 3.1E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12595 f567313667c4bc78e1703a30e29c255e 342 SUPERFAMILY SSF53850 130 305 2.71E-8 T 06-07-2017 CAL12_RS12595 f567313667c4bc78e1703a30e29c255e 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 339 1.3E-92 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10210 64e1f9e75cbd32bcbdf7c30a8a7e7200 246 SUPERFAMILY SSF53901 32 170 2.59E-8 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS10210 64e1f9e75cbd32bcbdf7c30a8a7e7200 246 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 22 242 1.5E-73 T 06-07-2017 IPR014030 Beta-ketoacyl synthase, N-terminal CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 Pfam PF00293 NUDIX domain 7 136 2.0E-23 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.2E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.2E-6 T 06-07-2017 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 SUPERFAMILY SSF55811 6 165 4.98E-31 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 Gene3D G3DSA:3.90.79.10 7 152 1.1E-29 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 38.033 T 06-07-2017 IPR022927 RNA pyrophosphohydrolase RppH CAL12_RS22610 38a7e22677bae74eba5d88242b2ac730 190 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 06-07-2017 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CAL12_RS08240 6a1b8b7e27b0dea12b10c1418714486f 117 Pfam PF01042 Endoribonuclease L-PSP 6 115 2.1E-24 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS08240 6a1b8b7e27b0dea12b10c1418714486f 117 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 06-07-2017 IPR019897 RidA, conserved site CAL12_RS08240 6a1b8b7e27b0dea12b10c1418714486f 117 Gene3D G3DSA:3.30.1330.40 13 115 2.3E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS08240 6a1b8b7e27b0dea12b10c1418714486f 117 SUPERFAMILY SSF55298 13 116 4.24E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 7 388 4.3E-164 T 06-07-2017 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 Gene3D G3DSA:3.10.310.10 6 189 1.2E-81 T 06-07-2017 CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 Gene3D G3DSA:3.10.310.10 190 368 1.0E-64 T 06-07-2017 CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 SUPERFAMILY SSF54506 6 175 9.42E-67 T 06-07-2017 CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 Pfam PF04303 PrpF protein 7 386 2.5E-147 T 06-07-2017 IPR007400 PrpF protein CAL12_RS21335 6756314b96f604f69a8761c1d91622f7 394 SUPERFAMILY SSF54506 184 389 9.42E-64 T 06-07-2017 CAL12_RS23935 969e1de10d577b2470decd9356203bac 228 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 27 220 5.9E-61 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 CAL12_RS23935 969e1de10d577b2470decd9356203bac 228 Pfam PF12804 MobA-like NTP transferase domain 29 190 1.6E-30 T 06-07-2017 IPR025877 MobA-like NTP transferase CAL12_RS23935 969e1de10d577b2470decd9356203bac 228 Gene3D G3DSA:3.90.550.10 26 225 1.6E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS23935 969e1de10d577b2470decd9356203bac 228 SUPERFAMILY SSF53448 27 220 1.84E-27 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS23935 969e1de10d577b2470decd9356203bac 228 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 25 223 26.538 T 06-07-2017 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 Gene3D G3DSA:3.40.50.720 1 239 3.4E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 SUPERFAMILY SSF51735 1 242 1.43E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.6E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.6E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.6E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.6E-15 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS01515 cfd4618999c29d59754c1b90a78d9f2f 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 239 2.1E-25 T 06-07-2017 CAL12_RS02625 9054842d8ef62f1ad302db333a86f403 335 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 316 9.0E-33 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS20470 61109089f9a1d2772ac87baf8426f0ec 239 SUPERFAMILY SSF52499 10 234 2.22E-30 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS20470 61109089f9a1d2772ac87baf8426f0ec 239 Gene3D G3DSA:3.40.50.850 11 234 5.6E-30 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS20470 61109089f9a1d2772ac87baf8426f0ec 239 Pfam PF00857 Isochorismatase family 24 201 5.7E-21 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS16015 faf22406748735f4a9a30a4c51bb5a90 78 Gene3D G3DSA:1.10.260.40 2 70 7.9E-14 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS16015 faf22406748735f4a9a30a4c51bb5a90 78 SMART SM00530 6 62 0.0012 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS16015 faf22406748735f4a9a30a4c51bb5a90 78 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 67 5.6E-22 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS16015 faf22406748735f4a9a30a4c51bb5a90 78 SUPERFAMILY SSF47413 2 69 2.73E-17 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS08625 39d888d27e3ca934975fa3a55f19e1b0 305 SUPERFAMILY SSF161098 97 287 1.96E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08625 39d888d27e3ca934975fa3a55f19e1b0 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 303 8.3E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08625 39d888d27e3ca934975fa3a55f19e1b0 305 Gene3D G3DSA:1.10.3720.10 93 300 1.1E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08625 39d888d27e3ca934975fa3a55f19e1b0 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 79 8.2E-12 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS11490 cb094406723c334ad0b58711bd2a606e 140 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1 36 4.8E-7 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11490 cb094406723c334ad0b58711bd2a606e 140 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 41 140 1.9E-24 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS14975 584256bd4624056d7705a74405a6a551 153 Pfam PF13581 Histidine kinase-like ATPase domain 16 149 9.8E-14 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS03990 7ab6cf1fcc51e3259380ef12f7b3b585 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 80 9.4E-18 T 06-07-2017 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CAL12_RS03990 7ab6cf1fcc51e3259380ef12f7b3b585 248 Gene3D G3DSA:3.20.20.190 3 235 2.1E-36 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAL12_RS03990 7ab6cf1fcc51e3259380ef12f7b3b585 248 SUPERFAMILY SSF51695 6 166 1.86E-36 T 06-07-2017 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CAL12_RS27595 467b14560a5ac0ca126b93415d2fa903 128 Pfam PF01042 Endoribonuclease L-PSP 12 125 4.1E-32 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS27595 467b14560a5ac0ca126b93415d2fa903 128 Gene3D G3DSA:3.30.1330.40 1 127 5.8E-39 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS27595 467b14560a5ac0ca126b93415d2fa903 128 SUPERFAMILY SSF55298 1 127 9.27E-41 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS04340 03c04bf973078432beef95452ebf0b9b 91 Pfam PF11804 Protein of unknown function (DUF3325) 4 89 7.0E-19 T 06-07-2017 IPR021762 Protein of unknown function DUF3325 CAL12_RS26330 a62347ad0fb0f6234af0bce8814e8e03 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 3.9E-53 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26330 a62347ad0fb0f6234af0bce8814e8e03 324 PIRSF PIRSF017082 1 324 2.5E-57 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02315 d4575a5a1d041e6b37d54c83a32f5919 386 Pfam PF07690 Major Facilitator Superfamily 14 248 4.5E-9 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS02315 d4575a5a1d041e6b37d54c83a32f5919 386 Gene3D G3DSA:1.20.1250.20 200 377 1.7E-4 T 06-07-2017 CAL12_RS02315 d4575a5a1d041e6b37d54c83a32f5919 386 Gene3D G3DSA:1.20.1250.20 10 185 6.2E-12 T 06-07-2017 CAL12_RS02315 d4575a5a1d041e6b37d54c83a32f5919 386 SUPERFAMILY SSF103473 3 377 1.09E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 PIRSF PIRSF000138 16 410 6.2E-119 T 06-07-2017 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 SUPERFAMILY SSF51395 32 222 1.65E-84 T 06-07-2017 CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 SUPERFAMILY SSF51395 254 406 1.65E-84 T 06-07-2017 CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 304 310 - T 06-07-2017 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 Gene3D G3DSA:3.20.20.70 32 408 4.2E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS02010 2d61b57f55cfb1ea441aec972121f415 410 Pfam PF01070 FMN-dependent dehydrogenase 42 406 1.1E-115 T 06-07-2017 IPR000262 FMN-dependent dehydrogenase GO:0016491 CAL12_RS08110 448f756dc07140d2d866751f6770fd11 508 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 266 470 1.0E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08110 448f756dc07140d2d866751f6770fd11 508 Gene3D G3DSA:1.10.3720.10 243 466 1.1E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08110 448f756dc07140d2d866751f6770fd11 508 SUPERFAMILY SSF161098 250 447 1.09E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS26075 ff9784f9e9a9dd729c46dd99c7f0693a 304 Pfam PF13098 Thioredoxin-like domain 172 296 2.5E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26075 ff9784f9e9a9dd729c46dd99c7f0693a 304 Gene3D G3DSA:3.10.450.70 88 147 1.1E-7 T 06-07-2017 IPR009094 Disulphide bond isomerase, DsbC, N-terminal CAL12_RS26075 ff9784f9e9a9dd729c46dd99c7f0693a 304 Pfam PF10411 Disulfide bond isomerase protein N-terminus 94 143 3.1E-13 T 06-07-2017 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal CAL12_RS26075 ff9784f9e9a9dd729c46dd99c7f0693a 304 SUPERFAMILY SSF52833 157 298 7.0E-31 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS26075 ff9784f9e9a9dd729c46dd99c7f0693a 304 Gene3D G3DSA:3.40.30.10 170 300 5.4E-35 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 Pfam PF03741 Integral membrane protein TerC family 14 203 6.0E-48 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 SMART SM01091 432 517 1.4E-20 T 06-07-2017 IPR005170 Transporter-associated domain CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 SUPERFAMILY SSF54631 288 422 1.95E-17 T 06-07-2017 CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 SUPERFAMILY SSF56176 429 520 1.55E-18 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 Gene3D G3DSA:3.30.465.10 414 516 6.5E-22 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 Gene3D G3DSA:3.10.580.10 287 413 1.7E-8 T 06-07-2017 CAL12_RS07585 68b9ed3acd52a58832761e611765c405 529 Pfam PF03471 Transporter associated domain 434 516 8.7E-20 T 06-07-2017 IPR005170 Transporter-associated domain CAL12_RS12430 c9e8985e6e548418c672d43996f03521 258 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 14 224 8.5E-35 T 06-07-2017 IPR008775 Phytanoyl-CoA dioxygenase CAL12_RS12430 c9e8985e6e548418c672d43996f03521 258 SUPERFAMILY SSF51197 2 253 1.3E-58 T 06-07-2017 CAL12_RS12430 c9e8985e6e548418c672d43996f03521 258 Gene3D G3DSA:2.60.120.620 3 249 1.1E-55 T 06-07-2017 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 Gene3D G3DSA:3.30.1130.10 14 127 7.4E-36 T 06-07-2017 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 SUPERFAMILY SSF55620 177 273 6.52E-10 T 06-07-2017 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 PIRSF PIRSF004750 1 275 5.4E-113 T 06-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 14 122 4.9E-41 T 06-07-2017 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 275 141.382 T 06-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 Pfam PF14489 QueF-like protein 187 260 3.3E-26 T 06-07-2017 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 TIGRFAM TIGR03138 QueF: queuine synthase 3 275 8.4E-113 T 06-07-2017 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 CAL12_RS08905 b282e81716c69a3ee33d6f78c7578234 275 Gene3D G3DSA:3.30.1130.10 138 260 3.9E-49 T 06-07-2017 CAL12_RS22170 94175a73c668fd07324fe2de67496349 154 Gene3D G3DSA:3.30.1460.10 3 131 2.5E-20 T 06-07-2017 CAL12_RS22170 94175a73c668fd07324fe2de67496349 154 SUPERFAMILY SSF69635 2 140 1.32E-27 T 06-07-2017 CAL12_RS22170 94175a73c668fd07324fe2de67496349 154 Pfam PF05932 Tir chaperone protein (CesT) family 5 125 6.3E-22 T 06-07-2017 IPR010261 Tir chaperone protein (CesT) family GO:0005737|GO:0050708 CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 SMART SM00062 39 276 1.6E-27 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 Gene3D G3DSA:3.40.190.10 117 206 4.8E-6 T 06-07-2017 CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 SUPERFAMILY SSF53850 40 273 3.08E-40 T 06-07-2017 CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 Gene3D G3DSA:3.40.190.10 37 116 2.8E-26 T 06-07-2017 CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 Gene3D G3DSA:3.40.190.10 235 273 2.8E-26 T 06-07-2017 CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 273 4.5E-43 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS25950 9150877b520f1caa84adbb9a420e6702 293 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 7 278 5.7E-62 T 06-07-2017 IPR014337 Ectoine/Hydroxyectoine-binding protein EhuB GO:0005886|GO:0033294|GO:0051470|GO:0051471 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 Gene3D G3DSA:3.40.190.10 93 175 9.7E-18 T 06-07-2017 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 Gene3D G3DSA:3.40.190.10 176 264 1.6E-17 T 06-07-2017 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 Pfam PF03466 LysR substrate binding domain 89 287 2.7E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 SUPERFAMILY SSF53850 90 289 5.5E-33 T 06-07-2017 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 SUPERFAMILY SSF46785 1 85 3.18E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.9E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.5E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10680 c53e9aa6488d97213ff23fd41b28d24a 301 Gene3D G3DSA:1.10.10.10 1 86 6.5E-27 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03960 4e755101af0bc7deddeb124ed06c23a4 301 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 22 276 1.4E-13 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAL12_RS03960 4e755101af0bc7deddeb124ed06c23a4 301 Gene3D G3DSA:3.40.50.1820 3 142 4.7E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03960 4e755101af0bc7deddeb124ed06c23a4 301 Gene3D G3DSA:3.40.50.1820 227 298 4.7E-59 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03960 4e755101af0bc7deddeb124ed06c23a4 301 SUPERFAMILY SSF53474 2 147 5.08E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03960 4e755101af0bc7deddeb124ed06c23a4 301 SUPERFAMILY SSF53474 176 298 5.08E-46 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25465 9f7ae38c4bd3e455145c65677731e70b 301 Pfam PF07285 Protein of unknown function (DUF1444) 118 296 3.0E-6 T 06-07-2017 IPR010838 Protein of unknown unction DUF1444 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 134 141 - T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 Gene3D G3DSA:3.40.50.1370 89 225 8.7E-49 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 Gene3D G3DSA:3.40.50.1370 226 384 4.7E-45 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 124 146 3.9E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 172 3.9E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 217 234 3.9E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 378 392 3.9E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00101 Aspartate carbamoyltransferase signature 312 321 3.9E-29 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 90 397 5.4E-87 T 06-07-2017 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 347 356 4.7E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 153 4.7E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 362 385 4.7E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 218 229 4.7E-19 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 SUPERFAMILY SSF53671 89 398 2.36E-86 T 06-07-2017 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 90 229 1.9E-38 T 06-07-2017 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CAL12_RS09440 59f2d6f954d0bea55b10e90b7c35ccd6 429 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 242 395 1.1E-26 T 06-07-2017 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CAL12_RS11335 48eec36b132c7854303ce9a1c8742a11 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 131 2.0E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS14235 6b6ba54e9f7994d959a9017093832fb4 223 Gene3D G3DSA:1.20.910.10 1 207 1.4E-20 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS14235 6b6ba54e9f7994d959a9017093832fb4 223 SUPERFAMILY SSF48613 1 214 5.29E-56 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS14235 6b6ba54e9f7994d959a9017093832fb4 223 SMART SM01236 72 170 1.7E-5 T 06-07-2017 CAL12_RS14235 6b6ba54e9f7994d959a9017093832fb4 223 Pfam PF14518 Iron-containing redox enzyme 39 206 9.9E-26 T 06-07-2017 IPR028201 PqqC-like protein CAL12_RS15620 f2769bfcc979c317df354e0f054ae87a 254 Pfam PF11738 Protein of unknown function (DUF3298) 171 239 9.9E-12 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAL12_RS15620 f2769bfcc979c317df354e0f054ae87a 254 Gene3D G3DSA:3.90.640.20 168 251 8.9E-19 T 06-07-2017 IPR021729 Domain of unknown function DUF3298 CAL12_RS13650 1b73ebaf8ac8e1099c1e2ca97c572d85 680 SUPERFAMILY SSF56300 20 297 6.14E-36 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS13650 1b73ebaf8ac8e1099c1e2ca97c572d85 680 Gene3D G3DSA:3.60.21.10 20 301 3.8E-32 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS13650 1b73ebaf8ac8e1099c1e2ca97c572d85 680 Pfam PF00149 Calcineurin-like phosphoesterase 22 234 5.1E-14 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS26870 5822144ac5a0284ba0e2140a4589c38e 303 Gene3D G3DSA:3.40.50.970 7 161 1.9E-33 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS26870 5822144ac5a0284ba0e2140a4589c38e 303 Pfam PF02779 Transketolase, pyrimidine binding domain 19 159 1.3E-17 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS26870 5822144ac5a0284ba0e2140a4589c38e 303 SMART SM00861 1 162 1.4E-21 T 06-07-2017 IPR005475 Transketolase-like, pyrimidine-binding domain CAL12_RS26870 5822144ac5a0284ba0e2140a4589c38e 303 SUPERFAMILY SSF52518 13 161 6.42E-35 T 06-07-2017 IPR029061 Thiamin diphosphate-binding fold CAL12_RS08890 02989f55c9f599584a0963ecc878d894 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAL12_RS08890 02989f55c9f599584a0963ecc878d894 190 PIRSF PIRSF000847 1 190 6.6E-46 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAL12_RS08890 02989f55c9f599584a0963ecc878d894 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 7.1E-18 T 06-07-2017 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CAL12_RS08890 02989f55c9f599584a0963ecc878d894 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 186 2.0E-52 T 06-07-2017 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 CAL12_RS11165 630f9572decb06838233f5241dda6063 380 Pfam PF00326 Prolyl oligopeptidase family 178 378 1.0E-11 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAL12_RS11165 630f9572decb06838233f5241dda6063 380 SUPERFAMILY SSF53474 25 380 4.15E-64 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11165 630f9572decb06838233f5241dda6063 380 Gene3D G3DSA:1.20.1440.110 25 119 1.5E-12 T 06-07-2017 CAL12_RS11165 630f9572decb06838233f5241dda6063 380 Gene3D G3DSA:3.40.50.1820 129 380 1.0E-48 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10070 8f74a4210066c7a0b7d7a028da771201 415 SUPERFAMILY SSF75304 15 412 3.66E-97 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS10070 8f74a4210066c7a0b7d7a028da771201 415 Gene3D G3DSA:3.90.1300.10 16 409 1.1E-100 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS10070 8f74a4210066c7a0b7d7a028da771201 415 Pfam PF01425 Amidase 36 399 3.0E-66 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS19975 d22b21201deda900061abb4046c067c4 172 Gene3D G3DSA:2.40.128.20 5 170 1.8E-35 T 06-07-2017 IPR012674 Calycin CAL12_RS19975 d22b21201deda900061abb4046c067c4 172 Pfam PF08212 Lipocalin-like domain 28 168 6.0E-38 T 06-07-2017 IPR000566 Lipocalin/cytosolic fatty-acid binding domain CAL12_RS19975 d22b21201deda900061abb4046c067c4 172 PIRSF PIRSF036893 1 172 1.4E-33 T 06-07-2017 IPR022271 Lipocalin, ApoD type CAL12_RS19975 d22b21201deda900061abb4046c067c4 172 SUPERFAMILY SSF50814 10 170 3.12E-33 T 06-07-2017 IPR011038 Calycin-like CAL12_RS06690 dddea3507b9211e29d4eda80bd2aba07 225 Pfam PF01965 DJ-1/PfpI family 2 162 5.4E-33 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS06690 dddea3507b9211e29d4eda80bd2aba07 225 Gene3D G3DSA:3.40.50.880 1 210 1.8E-64 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS06690 dddea3507b9211e29d4eda80bd2aba07 225 SUPERFAMILY SSF52317 1 181 1.17E-52 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS24355 6ad779ac6bf672e80f24f69ae8275692 333 SUPERFAMILY SSF51197 41 292 5.04E-15 T 06-07-2017 CAL12_RS24355 6ad779ac6bf672e80f24f69ae8275692 333 PIRSF PIRSF019543 2 330 5.5E-22 T 06-07-2017 IPR014503 Clavaminate synthase GO:0005506|GO:0017000|GO:0033758|GO:0055114 CAL12_RS24355 6ad779ac6bf672e80f24f69ae8275692 333 Gene3D G3DSA:3.60.130.10 67 311 3.9E-18 T 06-07-2017 CAL12_RS18475 79a81fefdc97ca50c538a1227c2e6518 278 SUPERFAMILY SSF52540 16 230 4.26E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18475 79a81fefdc97ca50c538a1227c2e6518 278 Pfam PF00005 ABC transporter 38 177 5.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS18475 79a81fefdc97ca50c538a1227c2e6518 278 Gene3D G3DSA:3.40.50.300 7 226 2.9E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS18475 79a81fefdc97ca50c538a1227c2e6518 278 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS18475 79a81fefdc97ca50c538a1227c2e6518 278 SMART SM00382 46 227 1.1E-14 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS01865 d19ac90a766a1fc8b860127ddc350a5f 471 Gene3D G3DSA:3.30.1330.120 293 415 1.9E-13 T 06-07-2017 CAL12_RS01865 d19ac90a766a1fc8b860127ddc350a5f 471 Pfam PF03972 MmgE/PrpD family 13 451 2.4E-95 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS01865 d19ac90a766a1fc8b860127ddc350a5f 471 SUPERFAMILY SSF103378 11 467 3.92E-92 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS02970 8b8f0355c2ace50c98e4e57da68fcbc0 162 Pfam PF01029 NusB family 20 148 8.1E-30 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAL12_RS02970 8b8f0355c2ace50c98e4e57da68fcbc0 162 SUPERFAMILY SSF48013 17 152 1.57E-36 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAL12_RS02970 8b8f0355c2ace50c98e4e57da68fcbc0 162 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 19 150 1.4E-36 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAL12_RS02970 8b8f0355c2ace50c98e4e57da68fcbc0 162 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 17 152 20.497 T 06-07-2017 IPR011605 NusB antitermination factor GO:0006353 CAL12_RS02970 8b8f0355c2ace50c98e4e57da68fcbc0 162 Gene3D G3DSA:1.10.940.10 18 156 5.1E-36 T 06-07-2017 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CAL12_RS03635 6bb1721846505dfc00d8805eb58cadbc 447 Gene3D G3DSA:3.40.50.1820 371 426 1.5E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03635 6bb1721846505dfc00d8805eb58cadbc 447 Gene3D G3DSA:3.40.50.1820 225 308 1.5E-6 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03635 6bb1721846505dfc00d8805eb58cadbc 447 SUPERFAMILY SSF53474 109 152 1.33E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03635 6bb1721846505dfc00d8805eb58cadbc 447 SUPERFAMILY SSF53474 325 421 1.33E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03635 6bb1721846505dfc00d8805eb58cadbc 447 SUPERFAMILY SSF53474 213 280 1.33E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27815 90118511e8df65bc6a792c896e3d7191 462 Gene3D G3DSA:3.40.605.10 7 244 2.2E-66 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27815 90118511e8df65bc6a792c896e3d7191 462 Pfam PF00171 Aldehyde dehydrogenase family 5 456 1.1E-123 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS27815 90118511e8df65bc6a792c896e3d7191 462 Gene3D G3DSA:3.40.309.10 245 431 1.4E-55 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS27815 90118511e8df65bc6a792c896e3d7191 462 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS27815 90118511e8df65bc6a792c896e3d7191 462 SUPERFAMILY SSF53720 6 460 1.44E-130 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS22905 b1e990c17f6d92270b0bb1acd1ada689 105 Gene3D G3DSA:3.30.70.900 2 104 1.0E-27 T 06-07-2017 CAL12_RS22905 b1e990c17f6d92270b0bb1acd1ada689 105 Pfam PF07978 NIPSNAP 4 104 8.3E-32 T 06-07-2017 IPR012577 NIPSNAP CAL12_RS22905 b1e990c17f6d92270b0bb1acd1ada689 105 SUPERFAMILY SSF54909 1 104 3.33E-33 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 ProSitePatterns PS00855 Signal peptidases II signature. 118 130 - T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 66 74 6.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 115 130 6.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 151 167 6.3E-18 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 TIGRFAM TIGR00077 lspA: signal peptidase II 24 175 8.1E-40 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 Pfam PF01252 Signal peptidase (SPase) II 29 169 4.8E-37 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS17300 5fb38c2eaaa6cc21b4c8215f61520aa4 177 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 20 176 16.906 T 06-07-2017 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 21 351 3.4E-101 T 06-07-2017 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 SUPERFAMILY SSF52540 149 276 2.42E-5 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 SUPERFAMILY SSF52821 4 69 2.2E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 SUPERFAMILY SSF52821 97 141 2.2E-19 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 Gene3D G3DSA:3.40.250.10 19 135 1.9E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 6 367 51.086 T 06-07-2017 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 CAL12_RS25850 37f25e529d627eb310c32d1e65002ffe 373 SMART SM00450 7 138 3.4E-7 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS25575 a7ff1de6ff3154fef4104fb841ca490f 304 SUPERFAMILY SSF47240 9 276 2.54E-46 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS25575 a7ff1de6ff3154fef4104fb841ca490f 304 Gene3D G3DSA:1.10.620.20 8 177 2.5E-21 T 06-07-2017 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 SUPERFAMILY SSF56784 1 165 1.32E-42 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 PIRSF PIRSF004682 1 187 1.6E-54 T 06-07-2017 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 Gene3D G3DSA:3.40.50.1000 1 182 9.5E-47 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 154 2.5E-29 T 06-07-2017 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 150 3.0E-33 T 06-07-2017 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CAL12_RS22975 363a2112d2a362de2c67ccd809aa7bb1 198 Pfam PF13242 HAD-hyrolase-like 108 177 4.4E-10 T 06-07-2017 CAL12_RS20000 983678088fc167b4f66e9dd5044f7ada 426 Pfam PF01593 Flavin containing amine oxidoreductase 10 284 4.5E-21 T 06-07-2017 IPR002937 Amine oxidase GO:0016491|GO:0055114 CAL12_RS20000 983678088fc167b4f66e9dd5044f7ada 426 SUPERFAMILY SSF51905 380 411 1.52E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20000 983678088fc167b4f66e9dd5044f7ada 426 SUPERFAMILY SSF51905 1 300 1.52E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20000 983678088fc167b4f66e9dd5044f7ada 426 Gene3D G3DSA:3.50.50.60 201 306 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS20000 983678088fc167b4f66e9dd5044f7ada 426 Gene3D G3DSA:3.50.50.60 1 106 1.8E-33 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 29 49 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 10 29 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 49 68 7.3E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 Pfam PF00813 FliP family 13 217 2.0E-67 T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 TIGRFAM TIGR01102 yscR: type III secretion apparatus protein, YscR/HrcR family 9 217 3.3E-79 T 06-07-2017 IPR005773 Yop virulence translocation protein R GO:0015031|GO:0016021 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS22055 e7f208fb6687e888756b5c48ed912591 222 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 06-07-2017 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CAL12_RS21135 19045ff7e69b9868ab24a638ab6989a3 488 SUPERFAMILY SSF75304 12 476 3.4E-120 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS21135 19045ff7e69b9868ab24a638ab6989a3 488 Gene3D G3DSA:3.90.1300.10 12 480 5.1E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS21135 19045ff7e69b9868ab24a638ab6989a3 488 Pfam PF01425 Amidase 35 466 3.0E-87 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS22895 9c91cb28af2aa571d837afd124d09049 330 PIRSF PIRSF017082 1 329 9.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22895 9c91cb28af2aa571d837afd124d09049 330 SUPERFAMILY SSF53850 119 291 2.48E-10 T 06-07-2017 CAL12_RS22895 9c91cb28af2aa571d837afd124d09049 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 326 2.2E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12630 5ebb8e17dee2ba287525a6d5baa37bf2 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 257 6.4E-48 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS12630 5ebb8e17dee2ba287525a6d5baa37bf2 258 Gene3D G3DSA:3.90.226.10 5 257 8.8E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12630 5ebb8e17dee2ba287525a6d5baa37bf2 258 SUPERFAMILY SSF52096 5 257 2.31E-76 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12630 5ebb8e17dee2ba287525a6d5baa37bf2 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 Pfam PF13629 Pilus formation protein N terminal region 17 83 5.7E-12 T 06-07-2017 IPR032789 Pilus formation protein, N-terminal CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 Pfam PF00263 Bacterial type II and III secretion system protein 230 385 4.3E-41 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 PRINTS PR00811 Bacterial general secretion pathway protein D signature 373 387 1.0E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 PRINTS PR00811 Bacterial general secretion pathway protein D signature 350 368 1.0E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 PRINTS PR00811 Bacterial general secretion pathway protein D signature 151 161 1.0E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS09580 e5bd48600c2531b083eb4d4ddc2ab507 456 PRINTS PR00811 Bacterial general secretion pathway protein D signature 225 249 1.0E-8 T 06-07-2017 IPR001775 GspD/PilQ family CAL12_RS26630 77ab91d03375750d503ea7b48648397f 75 Pfam PF06945 Protein of unknown function (DUF1289) 25 69 5.1E-18 T 06-07-2017 IPR010710 Protein of unknown function DUF1289 CAL12_RS13815 904d195cec5bd07ea19ed52b6b4e09a4 359 Gene3D G3DSA:3.40.50.720 7 333 7.3E-57 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13815 904d195cec5bd07ea19ed52b6b4e09a4 359 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 247 7.6E-25 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS13815 904d195cec5bd07ea19ed52b6b4e09a4 359 SUPERFAMILY SSF51735 6 337 1.16E-61 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22555 a185a71b0c511c78372788230120f0ed 103 SUPERFAMILY SSF102829 3 97 1.96E-21 T 06-07-2017 IPR007838 Cell division protein ZapA-like CAL12_RS22555 a185a71b0c511c78372788230120f0ed 103 Pfam PF05164 Cell division protein ZapA 4 89 4.5E-20 T 06-07-2017 IPR007838 Cell division protein ZapA-like CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 Gene3D G3DSA:1.20.1250.20 249 436 7.0E-16 T 06-07-2017 CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 SUPERFAMILY SSF103473 234 441 6.15E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 SUPERFAMILY SSF103473 4 185 6.15E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 Gene3D G3DSA:1.20.1250.20 5 181 3.7E-30 T 06-07-2017 CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 Pfam PF07690 Major Facilitator Superfamily 7 395 5.4E-50 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS25150 dc8c252ee6530854a66e729f4148f88a 460 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 8 409 3.0E-74 T 06-07-2017 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CAL12_RS12275 0af9977ee3c0d98bdc638b926015a086 410 Pfam PF11862 Domain of unknown function (DUF3382) 4 96 2.3E-23 T 06-07-2017 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal CAL12_RS12275 0af9977ee3c0d98bdc638b926015a086 410 Pfam PF02653 Branched-chain amino acid transport system / permease component 106 391 2.0E-53 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS13120 03fc2371b9ed217f83290ca5b232d33a 341 Gene3D G3DSA:3.20.20.140 1 339 1.1E-83 T 06-07-2017 CAL12_RS13120 03fc2371b9ed217f83290ca5b232d33a 341 Pfam PF04909 Amidohydrolase 3 329 8.0E-55 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS13120 03fc2371b9ed217f83290ca5b232d33a 341 SUPERFAMILY SSF51556 1 335 3.72E-89 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 06-07-2017 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 2.4E-63 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 34.956 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 Pfam PF02542 YgbB family 5 158 1.5E-61 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 SUPERFAMILY SSF69765 4 160 1.96E-62 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS19605 254fb1e874f502f3d47aebd56baf8863 164 Gene3D G3DSA:3.30.1330.50 3 160 3.8E-67 T 06-07-2017 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 SUPERFAMILY SSF51735 5 181 1.26E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 180 2.1E-46 T 06-07-2017 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 Gene3D G3DSA:3.40.50.720 5 185 7.2E-40 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 Gene3D G3DSA:1.10.1040.10 186 253 8.8E-14 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 254 9.9E-18 T 06-07-2017 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 181 205 - T 06-07-2017 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726 CAL12_RS16315 6488889953ce2c71345ee051ce4a4857 312 SUPERFAMILY SSF48179 184 254 1.02E-14 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 Pfam PF03840 Preprotein translocase SecG subunit 8 76 3.3E-22 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 7 77 7.4E-25 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 3.9E-30 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 3.9E-30 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 3.9E-30 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20040 e8d785551f5a6253dfb54731818d0ede 169 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 3.9E-30 T 06-07-2017 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CAL12_RS20850 c58f9c8b3d6711d3cb0ce8ae8d9267de 330 PIRSF PIRSF017082 1 328 4.0E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20850 c58f9c8b3d6711d3cb0ce8ae8d9267de 330 SUPERFAMILY SSF53850 118 289 4.92E-17 T 06-07-2017 CAL12_RS20850 c58f9c8b3d6711d3cb0ce8ae8d9267de 330 Gene3D G3DSA:3.40.190.10 135 258 1.1E-8 T 06-07-2017 CAL12_RS20850 c58f9c8b3d6711d3cb0ce8ae8d9267de 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 325 1.2E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11980 cb01a1635312f725db42727e815d3ebd 122 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 13 80 2.1E-23 T 06-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CAL12_RS11980 cb01a1635312f725db42727e815d3ebd 122 Pfam PF04347 Flagellar biosynthesis protein, FliO 25 119 2.3E-21 T 06-07-2017 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CAL12_RS15375 15ea579566f74dd5109e9643d3f3e783 1997 SUPERFAMILY SSF50494 45 265 1.59E-11 T 06-07-2017 IPR009003 Peptidase S1, PA clan CAL12_RS15375 15ea579566f74dd5109e9643d3f3e783 1997 Gene3D G3DSA:2.40.10.10 87 275 2.9E-7 T 06-07-2017 CAL12_RS15375 15ea579566f74dd5109e9643d3f3e783 1997 Pfam PF00089 Trypsin 88 275 1.5E-7 T 06-07-2017 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CAL12_RS19895 2396f02b3cb05e20d3b52c72afa369e7 163 Pfam PF05974 Domain of unknown function (DUF892) 5 158 2.7E-62 T 06-07-2017 IPR010287 Domain of unknown function DUF892 CAL12_RS19895 2396f02b3cb05e20d3b52c72afa369e7 163 Gene3D G3DSA:1.20.1260.10 1 161 1.3E-69 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS19895 2396f02b3cb05e20d3b52c72afa369e7 163 SUPERFAMILY SSF47240 1 153 6.0E-57 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS16830 54e28c09c83a53ed95645c6c827bb9b4 484 Pfam PF01425 Amidase 42 467 5.9E-98 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS16830 54e28c09c83a53ed95645c6c827bb9b4 484 Gene3D G3DSA:3.90.1300.10 6 478 1.5E-121 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS16830 54e28c09c83a53ed95645c6c827bb9b4 484 SUPERFAMILY SSF75304 13 477 1.22E-115 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 Gene3D G3DSA:1.10.10.10 3 79 1.2E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 Gene3D G3DSA:3.40.190.10 178 264 2.7E-22 T 06-07-2017 CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 SUPERFAMILY SSF46785 3 112 3.88E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 Gene3D G3DSA:3.40.190.10 92 177 2.6E-18 T 06-07-2017 CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 SUPERFAMILY SSF53850 89 296 4.78E-41 T 06-07-2017 CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 3.5E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13590 35af3eca36234e4a54ed9c18d30104bd 304 Pfam PF03466 LysR substrate binding domain 89 293 2.5E-41 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 Gene3D G3DSA:1.10.10.60 140 194 1.5E-23 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 SUPERFAMILY SSF46689 142 191 2.24E-14 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 Pfam PF00072 Response regulator receiver domain 25 133 4.3E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 SUPERFAMILY SSF52172 25 137 3.56E-24 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 158 175 3.7E-8 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 175 195 3.7E-8 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 Gene3D G3DSA:3.40.50.2300 24 134 6.6E-23 T 06-07-2017 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 Pfam PF02954 Bacterial regulatory protein, Fis family 153 191 2.6E-12 T 06-07-2017 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CAL12_RS21305 1b2253197e5b88c66da4f25efa71101c 195 SMART SM00448 22 134 4.4E-18 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS04530 ff4fb90d9c421a0d7a2a6c2f0a36a750 320 SUPERFAMILY SSF53850 110 283 6.09E-13 T 06-07-2017 CAL12_RS04530 ff4fb90d9c421a0d7a2a6c2f0a36a750 320 PIRSF PIRSF017082 1 319 1.5E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04530 ff4fb90d9c421a0d7a2a6c2f0a36a750 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 1.9E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 Gene3D G3DSA:3.40.50.80 148 255 2.4E-25 T 06-07-2017 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 SUPERFAMILY SSF63380 42 138 4.54E-23 T 06-07-2017 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 SUPERFAMILY SSF54292 251 354 2.36E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 Gene3D G3DSA:2.40.30.10 40 139 2.2E-26 T 06-07-2017 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 SUPERFAMILY SSF52343 136 263 1.06E-27 T 06-07-2017 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 Gene3D G3DSA:3.10.20.30 256 352 1.5E-22 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 304 312 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 68 78 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 90 104 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 128 142 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 114 128 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 150 169 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 78 90 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 PRINTS PR00409 Phthalate dioxygenase reductase family signature 228 236 6.0E-32 T 06-07-2017 IPR000951 Phthalate dioxygenase reductase GO:0016491 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 276 346 3.6E-9 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23490 02e36bfa330e46ae9e0a8cec19f8b697 355 Pfam PF00175 Oxidoreductase NAD-binding domain 151 242 1.4E-6 T 06-07-2017 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CAL12_RS03015 6ea6b6cce01a03fed64a4a07dd8a18c6 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 301 1.4E-73 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS03015 6ea6b6cce01a03fed64a4a07dd8a18c6 324 PIRSF PIRSF006470 1 323 8.0E-73 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS03015 6ea6b6cce01a03fed64a4a07dd8a18c6 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 286 1.8E-62 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 Pfam PF01134 Glucose inhibited division protein A 8 399 4.5E-166 T 06-07-2017 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 628 2.2E-271 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 Gene3D G3DSA:3.50.50.60 6 236 1.3E-52 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 631 42.771 T 06-07-2017 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 06-07-2017 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 SUPERFAMILY SSF51905 6 66 1.09E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 SUPERFAMILY SSF51905 97 262 1.09E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 SMART SM01228 553 624 1.1E-43 T 06-07-2017 CAL12_RS27855 189e151d2b55e09102c4107d42122820 638 Pfam PF13932 GidA associated domain 403 623 5.1E-73 T 06-07-2017 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 CAL12_RS13695 20f12d529d7ec96037f2188e632184c3 185 Pfam PF12318 Membrane bound FAD containing D-sorbitol dehydrogenase 17 180 5.3E-42 T 06-07-2017 IPR024651 FAD-containing D-sorbitol dehydrogenase small subunit CAL12_RS11265 da7a2ac86ac40bcba3b6c1932d2604c2 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 1.2E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11265 da7a2ac86ac40bcba3b6c1932d2604c2 326 SUPERFAMILY SSF53850 114 288 3.26E-12 T 06-07-2017 CAL12_RS11265 da7a2ac86ac40bcba3b6c1932d2604c2 326 PIRSF PIRSF017082 1 325 3.1E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23030 e296983f93601ba09135177454efbfdb 289 Pfam PF13628 Domain of unknown function (DUF4142) 105 237 1.5E-37 T 06-07-2017 IPR025419 Domain of unknown function DUF4142 CAL12_RS23030 e296983f93601ba09135177454efbfdb 289 Gene3D G3DSA:1.20.1260.10 100 230 3.3E-9 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS04165 2f18c3f663fca19c6e9db815e04a4fd8 320 PIRSF PIRSF017082 1 320 7.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04165 2f18c3f663fca19c6e9db815e04a4fd8 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 314 3.4E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04165 2f18c3f663fca19c6e9db815e04a4fd8 320 SUPERFAMILY SSF53850 106 275 3.1E-14 T 06-07-2017 CAL12_RS23670 417d037ca56e15998a27d2c10ed955c3 42 SUPERFAMILY SSF51126 4 42 5.65E-8 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS23670 417d037ca56e15998a27d2c10ed955c3 42 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 12 41 3.7E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23670 417d037ca56e15998a27d2c10ed955c3 42 Gene3D G3DSA:2.160.20.20 2 42 9.8E-9 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23670 417d037ca56e15998a27d2c10ed955c3 42 Pfam PF12951 Passenger-associated-transport-repeat 13 42 4.3E-11 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS20195 37791d4185e1c95f325821dbcb4e3179 195 Pfam PF07424 TrbM 26 177 4.6E-58 T 06-07-2017 IPR009989 TrbM CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 PIRSF PIRSF000239 1 210 1.2E-80 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 192 8.3E-12 T 06-07-2017 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 Gene3D G3DSA:3.30.1020.10 159 212 1.1E-28 T 06-07-2017 CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 SUPERFAMILY SSF52833 4 210 1.91E-69 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 Gene3D G3DSA:3.40.30.10 5 158 2.3E-62 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS18855 ac851a19d5773a6f2a720327a3ecead5 213 Pfam PF00578 AhpC/TSA family 7 136 3.7E-33 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS26045 f104733d111fdd9018768d29680b24cb 243 SMART SM01236 78 181 3.4E-27 T 06-07-2017 CAL12_RS26045 f104733d111fdd9018768d29680b24cb 243 Gene3D G3DSA:1.20.910.10 2 239 4.6E-63 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS26045 f104733d111fdd9018768d29680b24cb 243 SUPERFAMILY SSF48613 10 226 3.53E-51 T 06-07-2017 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CAL12_RS26045 f104733d111fdd9018768d29680b24cb 243 Pfam PF14518 Iron-containing redox enzyme 44 213 8.2E-36 T 06-07-2017 IPR028201 PqqC-like protein CAL12_RS22280 3e89bd4ce22a994c207aea8b4daf6dec 128 Pfam PF00072 Response regulator receiver domain 8 118 8.3E-23 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22280 3e89bd4ce22a994c207aea8b4daf6dec 128 SUPERFAMILY SSF52172 7 123 8.25E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS22280 3e89bd4ce22a994c207aea8b4daf6dec 128 SMART SM00448 6 118 1.9E-29 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS22280 3e89bd4ce22a994c207aea8b4daf6dec 128 Gene3D G3DSA:3.40.50.2300 2 124 5.0E-30 T 06-07-2017 CAL12_RS20745 e5cb10860321382ac6bc875fffae2842 322 PIRSF PIRSF017082 3 322 1.1E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20745 e5cb10860321382ac6bc875fffae2842 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 9.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20745 e5cb10860321382ac6bc875fffae2842 322 SUPERFAMILY SSF53850 114 284 7.06E-6 T 06-07-2017 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00412 Epoxide hydrolase signature 118 131 5.1E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00412 Epoxide hydrolase signature 72 87 5.1E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00412 Epoxide hydrolase signature 132 145 5.1E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00412 Epoxide hydrolase signature 281 303 5.1E-5 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 Pfam PF12697 Alpha/beta hydrolase family 50 298 1.0E-16 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 Gene3D G3DSA:3.40.50.1820 8 304 7.1E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 8.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 72 87 8.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 118 131 8.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 PRINTS PR00111 Alpha/beta hydrolase fold signature 246 260 8.3E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23370 e9cab52510e4183887f41f9d1c3921ee 319 SUPERFAMILY SSF53474 18 304 9.57E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS15040 24221fc10d13602464696a7d153dbcd4 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 6.5E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15040 24221fc10d13602464696a7d153dbcd4 330 SUPERFAMILY SSF53850 118 291 1.38E-11 T 06-07-2017 CAL12_RS15040 24221fc10d13602464696a7d153dbcd4 330 PIRSF PIRSF017082 1 330 1.6E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05755 2d4693e32ad93fc33c55bc7991679975 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 3.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05755 2d4693e32ad93fc33c55bc7991679975 325 SUPERFAMILY SSF53850 113 286 4.78E-11 T 06-07-2017 CAL12_RS05755 2d4693e32ad93fc33c55bc7991679975 325 PIRSF PIRSF017082 2 325 3.0E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21780 cd0c7575eec385ee90abe8fbe4768eec 455 SUPERFAMILY SSF103378 11 445 7.06E-124 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS21780 cd0c7575eec385ee90abe8fbe4768eec 455 Gene3D G3DSA:3.30.1330.120 272 397 9.2E-25 T 06-07-2017 CAL12_RS21780 cd0c7575eec385ee90abe8fbe4768eec 455 Pfam PF03972 MmgE/PrpD family 14 437 4.6E-132 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 SMART SM01403 7 101 2.9E-55 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.918 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 Gene3D G3DSA:3.30.70.600 3 102 3.2E-43 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 SUPERFAMILY SSF54999 5 101 3.79E-37 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 6.2E-35 T 06-07-2017 IPR027486 Ribosomal protein S10 domain CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 06-07-2017 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.4E-18 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.4E-18 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.4E-18 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27660 a83a3107f7aaf2a9151973d2238a9ed3 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.6E-45 T 06-07-2017 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS25145 bd867391ac3ec52d8d23e3fc019e11f0 62 Pfam PF11943 Protein of unknown function (DUF3460) 4 61 1.3E-28 T 06-07-2017 IPR021853 Protein of unknown function DUF3460 CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 SUPERFAMILY SSF46785 10 92 2.56E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 Gene3D G3DSA:3.40.190.10 90 206 5.6E-15 T 06-07-2017 CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 Pfam PF03466 LysR substrate binding domain 96 287 2.3E-18 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 SUPERFAMILY SSF53850 98 291 3.18E-19 T 06-07-2017 CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 Gene3D G3DSA:1.10.10.10 10 89 2.8E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10840 2b9243c016e1c291d5e9bc795e17d44e 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 7.0E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 Pfam PF00107 Zinc-binding dehydrogenase 189 320 2.1E-16 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 Gene3D G3DSA:3.90.180.10 5 180 7.8E-22 T 06-07-2017 IPR011032 GroES-like CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 SMART SM00829 15 358 9.5E-4 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 Gene3D G3DSA:3.40.50.720 181 327 6.4E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 SUPERFAMILY SSF50129 5 189 3.04E-23 T 06-07-2017 IPR011032 GroES-like CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 142 5.5E-5 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS13835 1f48d58c59a6e883fbc8b75faf47f9b4 360 SUPERFAMILY SSF51735 161 327 8.25E-27 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08910 52f960c4dd21324510da3450e4bac8d5 308 SMART SM00382 30 226 4.0E-16 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08910 52f960c4dd21324510da3450e4bac8d5 308 SUPERFAMILY SSF52540 2 228 1.11E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08910 52f960c4dd21324510da3450e4bac8d5 308 Gene3D G3DSA:3.40.50.300 2 229 3.1E-67 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08910 52f960c4dd21324510da3450e4bac8d5 308 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08910 52f960c4dd21324510da3450e4bac8d5 308 Pfam PF00005 ABC transporter 21 163 1.2E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08205 072cc84983230935e9834ca7eff255bb 257 Gene3D G3DSA:3.40.50.300 2 244 8.0E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08205 072cc84983230935e9834ca7eff255bb 257 Pfam PF00005 ABC transporter 22 177 1.6E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08205 072cc84983230935e9834ca7eff255bb 257 SUPERFAMILY SSF52540 4 247 8.77E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08205 072cc84983230935e9834ca7eff255bb 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 2.1E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS08205 072cc84983230935e9834ca7eff255bb 257 SMART SM00382 30 224 4.1E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS18120 8a44d519dd6b679d87769b95a33ef9b9 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 314 7.3E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18120 8a44d519dd6b679d87769b95a33ef9b9 322 SUPERFAMILY SSF53850 111 285 1.69E-13 T 06-07-2017 CAL12_RS18120 8a44d519dd6b679d87769b95a33ef9b9 322 PIRSF PIRSF017082 1 322 3.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26790 ce4494d04522c2f58ff12721a0ff0b64 297 Gene3D G3DSA:3.20.10.10 129 284 2.0E-40 T 06-07-2017 CAL12_RS26790 ce4494d04522c2f58ff12721a0ff0b64 297 Gene3D G3DSA:3.30.470.10 11 126 1.6E-34 T 06-07-2017 CAL12_RS26790 ce4494d04522c2f58ff12721a0ff0b64 297 Pfam PF01063 Amino-transferase class IV 37 258 8.6E-40 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS26790 ce4494d04522c2f58ff12721a0ff0b64 297 SUPERFAMILY SSF56752 11 283 6.41E-72 T 06-07-2017 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CAL12_RS16055 ef9242fc7d0c08786971b0956f0ccd0a 326 PIRSF PIRSF017082 1 325 1.7E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16055 ef9242fc7d0c08786971b0956f0ccd0a 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 320 4.6E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16055 ef9242fc7d0c08786971b0956f0ccd0a 326 SUPERFAMILY SSF53850 116 289 1.59E-12 T 06-07-2017 CAL12_RS08125 1b3d966588a3fcf8dc36783093209425 562 Gene3D G3DSA:3.10.20.310 68 139 3.6E-7 T 06-07-2017 CAL12_RS08125 1b3d966588a3fcf8dc36783093209425 562 Pfam PF08479 POTRA domain, ShlB-type 67 139 2.1E-16 T 06-07-2017 IPR013686 Polypeptide-transport-associated, ShlB-type CAL12_RS08125 1b3d966588a3fcf8dc36783093209425 562 Gene3D G3DSA:2.40.160.50 174 557 1.5E-51 T 06-07-2017 CAL12_RS04150 6cea9ad80592296b6f50f0ccfc2e913a 284 SUPERFAMILY SSF103481 187 282 3.27E-9 T 06-07-2017 CAL12_RS04150 6cea9ad80592296b6f50f0ccfc2e913a 284 Pfam PF00892 EamA-like transporter family 144 282 4.8E-8 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS04150 6cea9ad80592296b6f50f0ccfc2e913a 284 SUPERFAMILY SSF103481 37 135 6.02E-13 T 06-07-2017 CAL12_RS14725 f725c932bbedb1ac01dd4213256b22a7 293 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 14 185 9.2E-39 T 06-07-2017 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CAL12_RS14725 f725c932bbedb1ac01dd4213256b22a7 293 Gene3D G3DSA:3.30.43.10 9 62 8.6E-19 T 06-07-2017 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CAL12_RS14725 f725c932bbedb1ac01dd4213256b22a7 293 SUPERFAMILY SSF56176 9 185 9.27E-45 T 06-07-2017 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CAL12_RS14725 f725c932bbedb1ac01dd4213256b22a7 293 Gene3D G3DSA:3.30.465.10 79 185 8.3E-29 T 06-07-2017 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CAL12_RS01800 ed681c05a694b12e94de35065ac13fa0 334 Pfam PF03741 Integral membrane protein TerC family 84 286 2.4E-53 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAL12_RS01800 ed681c05a694b12e94de35065ac13fa0 334 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 7 315 2.7E-120 T 06-07-2017 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 SUPERFAMILY SSF51735 19 269 2.57E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 26 223 1.6E-5 T 06-07-2017 CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 Gene3D G3DSA:3.40.50.720 19 269 2.7E-78 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 2.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 164 2.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 102 113 2.7E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 34 267 3.8E-57 T 06-07-2017 CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 166 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 102 113 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 231 251 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS00020 2bbb52498f208ee644e080fa07675846 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 4.0E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06735 44cc98c69956157663e7575e6da93161 460 SUPERFAMILY SSF103378 6 443 1.09E-108 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS06735 44cc98c69956157663e7575e6da93161 460 Pfam PF03972 MmgE/PrpD family 8 431 1.0E-110 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS06735 44cc98c69956157663e7575e6da93161 460 Gene3D G3DSA:3.30.1330.120 267 390 1.6E-18 T 06-07-2017 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 Gene3D G3DSA:1.10.3720.10 299 543 1.5E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 Gene3D G3DSA:1.10.3720.10 16 278 2.5E-44 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 275 2.1E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 365 536 2.5E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 SUPERFAMILY SSF161098 8 275 5.23E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07190 066d4ea3951b92759d4a2d9b16e59596 553 SUPERFAMILY SSF161098 304 541 1.44E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 7.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 Gene3D G3DSA:1.10.10.10 5 91 1.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 Gene3D G3DSA:3.40.190.10 109 181 7.1E-9 T 06-07-2017 CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 SUPERFAMILY SSF46785 6 90 9.53E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 Gene3D G3DSA:3.40.190.10 182 259 2.8E-13 T 06-07-2017 CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 SUPERFAMILY SSF53850 92 298 5.61E-29 T 06-07-2017 CAL12_RS23565 4c914304c24615f31c95e21d579f6c03 307 Pfam PF03466 LysR substrate binding domain 91 295 1.9E-23 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03735 28a690c4e197d6ada8bfa20023ac137e 322 SUPERFAMILY SSF53850 114 286 3.05E-13 T 06-07-2017 CAL12_RS03735 28a690c4e197d6ada8bfa20023ac137e 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 318 2.4E-62 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03735 28a690c4e197d6ada8bfa20023ac137e 322 Gene3D G3DSA:3.40.190.10 158 244 2.5E-4 T 06-07-2017 CAL12_RS03735 28a690c4e197d6ada8bfa20023ac137e 322 PIRSF PIRSF017082 1 322 5.1E-60 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01195 7030c1de3387b9699321201b40dc33a4 352 PIRSF PIRSF017082 17 324 1.1E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01195 7030c1de3387b9699321201b40dc33a4 352 SUPERFAMILY SSF53850 142 310 3.8E-9 T 06-07-2017 CAL12_RS01195 7030c1de3387b9699321201b40dc33a4 352 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 320 7.4E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01445 087262de874e6ded7c1d33f4bf628682 429 Gene3D G3DSA:3.40.50.10540 334 429 1.3E-113 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01445 087262de874e6ded7c1d33f4bf628682 429 Gene3D G3DSA:3.40.50.10540 20 245 1.3E-113 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01445 087262de874e6ded7c1d33f4bf628682 429 Pfam PF02515 CoA-transferase family III 23 405 2.5E-127 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS01445 087262de874e6ded7c1d33f4bf628682 429 SUPERFAMILY SSF89796 21 429 2.88E-137 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS01445 087262de874e6ded7c1d33f4bf628682 429 Gene3D G3DSA:3.30.1540.10 251 333 2.0E-31 T 06-07-2017 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 SUPERFAMILY SSF54292 11 87 8.91E-24 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 Gene3D G3DSA:1.10.150.120 84 166 1.6E-33 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 48 56 - T 06-07-2017 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 SUPERFAMILY SSF47741 93 166 1.7E-32 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 Pfam PF01799 [2Fe-2S] binding domain 82 154 8.9E-28 T 06-07-2017 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 63 6.0E-5 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS03280 534feb7add71f9745c56782180176a11 171 Gene3D G3DSA:3.10.20.30 11 83 2.7E-27 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS22705 ebeba1d0dd061ff519a376a78bb1e611 635 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 5 630 4.3E-176 T 06-07-2017 IPR010272 Type VI secretion system, TssF-like CAL12_RS22705 ebeba1d0dd061ff519a376a78bb1e611 635 Pfam PF05947 Type VI secretion system, ImpG, VasA, VC_A0110 6 629 2.7E-197 T 06-07-2017 IPR010272 Type VI secretion system, TssF-like CAL12_RS22705 ebeba1d0dd061ff519a376a78bb1e611 635 PIRSF PIRSF028304 1 632 2.0E-160 T 06-07-2017 IPR010272 Type VI secretion system, TssF-like CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 Pfam PF13840 ACT domain 346 409 5.8E-13 T 06-07-2017 IPR027795 GATS-like ACT domain CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 SUPERFAMILY SSF55021 261 357 6.22E-17 T 06-07-2017 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 PIRSF PIRSF000726 57 419 1.1E-132 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 412 5.1E-122 T 06-07-2017 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 412 4.4E-108 T 06-07-2017 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 1.3E-5 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 1.3E-5 T 06-07-2017 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 Reactome: R-HSA-70614 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 SUPERFAMILY SSF53633 4 250 6.28E-74 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 Gene3D G3DSA:3.40.1160.10 1 254 2.1E-74 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 Pfam PF01842 ACT domain 276 332 3.5E-7 T 06-07-2017 IPR002912 ACT domain GO:0008152|GO:0016597 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 06-07-2017 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 Pfam PF00696 Amino acid kinase family 3 229 2.1E-49 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS07630 3d2cc3651a67e1b15c97d967d447733f 421 SUPERFAMILY SSF55021 339 414 1.45E-22 T 06-07-2017 CAL12_RS25870 20a63136efbf80a95cc6339f33030c46 187 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 185 35.673 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS25870 20a63136efbf80a95cc6339f33030c46 187 Pfam PF02441 Flavoprotein 3 127 1.3E-25 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS25870 20a63136efbf80a95cc6339f33030c46 187 SUPERFAMILY SSF52507 2 181 5.1E-59 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS25870 20a63136efbf80a95cc6339f33030c46 187 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 179 8.0E-71 T 06-07-2017 IPR004507 Flavin prenyltransferase UbiX/Pad1 CAL12_RS25870 20a63136efbf80a95cc6339f33030c46 187 Gene3D G3DSA:3.40.50.1950 2 177 1.1E-71 T 06-07-2017 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 Gene3D G3DSA:3.40.50.720 2 203 4.9E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 SUPERFAMILY SSF51735 1 216 6.71E-53 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-17 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 Pfam PF00106 short chain dehydrogenase 6 194 2.0E-43 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS16570 17d7c3a64b02e3b2d1f5ae345bedd1a2 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 182 0.0096 T 06-07-2017 CAL12_RS03920 c42f9ffec98c610fbfdb354a9efad8eb 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 436 2.9E-131 T 06-07-2017 IPR002823 Protein of unknown function DUF112, transmembrane CAL12_RS14535 596260b0cfd872bc99b6e79c06cb7920 475 Gene3D G3DSA:3.40.605.10 6 262 5.6E-88 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS14535 596260b0cfd872bc99b6e79c06cb7920 475 SUPERFAMILY SSF53720 4 475 3.53E-158 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS14535 596260b0cfd872bc99b6e79c06cb7920 475 Pfam PF00171 Aldehyde dehydrogenase family 16 471 5.6E-155 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS14535 596260b0cfd872bc99b6e79c06cb7920 475 Gene3D G3DSA:3.40.309.10 263 452 8.6E-64 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS23950 a16ae57b706a2b2a06b532c40f390cdd 184 PIRSF PIRSF000216 17 184 1.8E-50 T 06-07-2017 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS23950 a16ae57b706a2b2a06b532c40f390cdd 184 SUPERFAMILY SSF52833 35 183 4.4E-49 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23950 a16ae57b706a2b2a06b532c40f390cdd 184 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 39 178 4.6E-44 T 06-07-2017 CAL12_RS23950 a16ae57b706a2b2a06b532c40f390cdd 184 Gene3D G3DSA:3.40.30.10 101 177 4.7E-9 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 Pfam PF01019 Gamma-glutamyltranspeptidase 43 580 2.3E-112 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 251 267 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 138 157 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 120 138 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 449 464 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 396 414 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 50 75 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 473 490 6.4E-30 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS23825 5f8805109017b846c3b3babd465d1122 587 SUPERFAMILY SSF56235 17 587 7.72E-137 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS23130 db31c2624702d41da670f063068af95a 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 274 5.2E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23130 db31c2624702d41da670f063068af95a 288 SUPERFAMILY SSF161098 81 263 8.37E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23130 db31c2624702d41da670f063068af95a 288 Gene3D G3DSA:1.10.3720.10 80 275 2.8E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23160 1b4d2316bf0ab358925022d640f842a1 313 Pfam PF03547 Membrane transport protein 8 141 1.2E-13 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAL12_RS23160 1b4d2316bf0ab358925022d640f842a1 313 Pfam PF03547 Membrane transport protein 155 305 5.5E-18 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAL12_RS24895 b7391d8bba7ceb981ba2f69fadd89a03 639 SMART SM00955 235 516 5.5E-64 T 06-07-2017 CAL12_RS24895 b7391d8bba7ceb981ba2f69fadd89a03 639 Pfam PF00773 RNB domain 474 514 1.9E-9 T 06-07-2017 CAL12_RS24895 b7391d8bba7ceb981ba2f69fadd89a03 639 Pfam PF00773 RNB domain 238 470 3.5E-35 T 06-07-2017 CAL12_RS24895 b7391d8bba7ceb981ba2f69fadd89a03 639 SUPERFAMILY SSF50249 233 566 4.57E-73 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS17550 2390890caa8fb7b71f0dd606ec8dcca4 156 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 3.0E-30 T 06-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CAL12_RS22440 34c1e87c13cc9f0b2b6e71afce84e0af 94 Pfam PF04999 Cell division protein FtsL 2 83 3.1E-17 T 06-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CAL12_RS22440 34c1e87c13cc9f0b2b6e71afce84e0af 94 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 1 83 3.3E-25 T 06-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CAL12_RS22440 34c1e87c13cc9f0b2b6e71afce84e0af 94 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 14.263 T 06-07-2017 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 CAL12_RS26810 5a025e07f4d47b138f70a16432ae251f 216 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 24 105 8.6E-5 T 06-07-2017 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CAL12_RS26810 5a025e07f4d47b138f70a16432ae251f 216 SUPERFAMILY SSF53474 3 215 8.45E-36 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS26810 5a025e07f4d47b138f70a16432ae251f 216 Gene3D G3DSA:3.40.50.1820 8 215 2.2E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 Gene3D G3DSA:3.40.640.10 133 337 3.7E-46 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 Gene3D G3DSA:3.90.1150.10 338 473 3.9E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 Pfam PF00155 Aminotransferase class I and II 127 468 2.6E-29 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 2.3E-11 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 SMART SM00345 9 68 1.7E-10 T 06-07-2017 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 SUPERFAMILY SSF53383 105 473 2.69E-87 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 SUPERFAMILY SSF46785 3 72 2.66E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09380 87f4e352cab186cc18928187ed2c5120 477 Gene3D G3DSA:1.10.10.10 2 69 1.7E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06485 91dc9297c55692a0a7561b9fdb8df8cb 348 Gene3D G3DSA:3.40.190.10 127 252 1.7E-21 T 06-07-2017 CAL12_RS06485 91dc9297c55692a0a7561b9fdb8df8cb 348 SUPERFAMILY SSF53850 32 281 2.85E-45 T 06-07-2017 CAL12_RS06485 91dc9297c55692a0a7561b9fdb8df8cb 348 Pfam PF13379 NMT1-like family 33 271 1.7E-28 T 06-07-2017 CAL12_RS27190 26f4625392d5499d2b550d2b9122fddd 380 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 100 374 1.5E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27190 26f4625392d5499d2b550d2b9122fddd 380 SUPERFAMILY SSF53850 165 336 7.24E-8 T 06-07-2017 CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.6E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 Gene3D G3DSA:3.40.50.720 6 253 2.8E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 201 0.0059 T 06-07-2017 CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 7.0E-60 T 06-07-2017 CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 SUPERFAMILY SSF51735 7 254 1.52E-70 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS05930 76986dac4ab856c06f0abac4d5b5a117 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.2E-34 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS09525 76675e24cd3e4f9f3f4fedf2348bbf8e 264 Pfam PF02602 Uroporphyrinogen-III synthase HemD 20 232 3.9E-25 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS09525 76675e24cd3e4f9f3f4fedf2348bbf8e 264 Gene3D G3DSA:3.40.50.10090 10 103 5.6E-15 T 06-07-2017 CAL12_RS09525 76675e24cd3e4f9f3f4fedf2348bbf8e 264 Gene3D G3DSA:3.40.50.10090 138 213 8.0E-6 T 06-07-2017 CAL12_RS09525 76675e24cd3e4f9f3f4fedf2348bbf8e 264 SUPERFAMILY SSF69618 9 236 3.14E-34 T 06-07-2017 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 SUPERFAMILY SSF46689 5 77 9.5E-16 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 Pfam PF01380 SIS domain 130 255 6.3E-18 T 06-07-2017 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 Gene3D G3DSA:1.10.10.10 4 78 1.2E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 Gene3D G3DSA:3.40.50.10490 99 269 2.5E-29 T 06-07-2017 CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 78 3.0E-13 T 06-07-2017 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CAL12_RS21500 d0ba37e767599d2af980cac5c2a3a3be 290 SUPERFAMILY SSF53697 98 280 2.49E-34 T 06-07-2017 CAL12_RS04210 840fe2c06ff8ed34f79af7cf52aebbb2 197 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 36 115 1.8E-9 T 06-07-2017 IPR025159 Transcriptional regulator, AbiEi antitoxin CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 153 244 3.3E-38 T 06-07-2017 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 400 7.8E-141 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Pfam PF13288 DXP reductoisomerase C-terminal domain 276 395 6.7E-36 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Gene3D G3DSA:1.10.1740.10 318 402 8.0E-26 T 06-07-2017 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 SUPERFAMILY SSF51735 5 157 1.11E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 SUPERFAMILY SSF55347 133 279 2.09E-61 T 06-07-2017 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Gene3D G3DSA:3.40.50.720 4 157 4.6E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 139 2.7E-40 T 06-07-2017 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 SUPERFAMILY SSF69055 307 401 3.14E-27 T 06-07-2017 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 PIRSF PIRSF006205 4 407 1.5E-144 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS12145 e83613d29d2c326ff7e43ed6a1980728 414 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 400 44.495 T 06-07-2017 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CAL12_RS13560 977ef605c973e0bdccf1ede38469e114 299 Gene3D G3DSA:2.60.130.10 7 297 6.2E-94 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAL12_RS13560 977ef605c973e0bdccf1ede38469e114 299 Pfam PF04444 Catechol dioxygenase N terminus 22 95 2.7E-30 T 06-07-2017 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CAL12_RS13560 977ef605c973e0bdccf1ede38469e114 299 Pfam PF00775 Dioxygenase 110 294 3.0E-46 T 06-07-2017 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CAL12_RS13560 977ef605c973e0bdccf1ede38469e114 299 SUPERFAMILY SSF49482 8 297 6.41E-86 T 06-07-2017 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CAL12_RS05670 cdd9c40d2e8c46c7c66811e21dfa7859 285 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 31 261 2.0E-49 T 06-07-2017 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CAL12_RS25325 47175b1a96678fc8a48721eb812504a6 226 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 198 4.7E-56 T 06-07-2017 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS25325 47175b1a96678fc8a48721eb812504a6 226 SUPERFAMILY SSF53271 10 223 2.49E-47 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS25325 47175b1a96678fc8a48721eb812504a6 226 Pfam PF00156 Phosphoribosyl transferase domain 49 171 7.9E-14 T 06-07-2017 IPR000836 Phosphoribosyltransferase domain GO:0009116 CAL12_RS25325 47175b1a96678fc8a48721eb812504a6 226 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 226 32.918 T 06-07-2017 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CAL12_RS25325 47175b1a96678fc8a48721eb812504a6 226 Gene3D G3DSA:3.40.50.2020 10 223 3.9E-75 T 06-07-2017 IPR029057 Phosphoribosyltransferase-like CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 SUPERFAMILY SSF90002 267 361 1.44E-25 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 Gene3D G3DSA:3.30.1220.10 235 361 2.9E-39 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 267 361 8.4E-22 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 193 1.1E-51 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 Gene3D G3DSA:3.40.50.300 9 211 3.2E-74 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 SMART SM00833 267 361 1.3E-17 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS26730 4901966564a6da1a1f5878ef0c3c7076 365 SUPERFAMILY SSF52540 12 221 2.98E-43 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 Pfam PF03466 LysR substrate binding domain 93 298 8.1E-39 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 Gene3D G3DSA:3.40.190.10 181 267 2.3E-21 T 06-07-2017 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 SUPERFAMILY SSF53850 95 300 1.76E-37 T 06-07-2017 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 Gene3D G3DSA:1.10.10.10 10 84 1.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 SUPERFAMILY SSF46785 6 116 1.65E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.3E-6 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 5.9E-20 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS13895 271d23fc48c47845d25719ebe3a57622 302 Gene3D G3DSA:3.40.190.10 95 180 7.7E-17 T 06-07-2017 CAL12_RS14215 a190021ed7cbdd05306d6a63b90519b4 339 Pfam PF04773 FecR protein 118 213 4.3E-18 T 06-07-2017 IPR006860 FecR protein CAL12_RS14215 a190021ed7cbdd05306d6a63b90519b4 339 PIRSF PIRSF018266 5 337 5.4E-86 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAL12_RS14215 a190021ed7cbdd05306d6a63b90519b4 339 Pfam PF16220 Domain of unknown function (DUF4880) 16 58 4.0E-15 T 06-07-2017 IPR032623 FecR, N-terminal CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 SUPERFAMILY SSF48498 79 185 4.26E-22 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.3E-15 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 SUPERFAMILY SSF46689 2 74 1.9E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 Gene3D G3DSA:1.10.10.60 2 59 2.3E-20 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 Gene3D G3DSA:1.10.357.10 60 185 1.2E-26 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS20560 cf2971dd495abaddcd6994c1764ec32a 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.5E-9 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS21685 83e64ec5e153ff63c775938db1aefffe 120 Pfam PF00034 Cytochrome c 26 112 6.0E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21685 83e64ec5e153ff63c775938db1aefffe 120 PRINTS PR00605 Class IC cytochrome C signature 87 109 4.6E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS21685 83e64ec5e153ff63c775938db1aefffe 120 PRINTS PR00605 Class IC cytochrome C signature 35 46 4.6E-5 T 06-07-2017 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 CAL12_RS21685 83e64ec5e153ff63c775938db1aefffe 120 Gene3D G3DSA:1.10.760.10 24 113 9.3E-27 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS21685 83e64ec5e153ff63c775938db1aefffe 120 SUPERFAMILY SSF46626 6 114 7.81E-23 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS23485 740eba42af61dd5db7bcce2744c0da2c 316 SUPERFAMILY SSF56529 83 301 1.83E-63 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS23485 740eba42af61dd5db7bcce2744c0da2c 316 Gene3D G3DSA:3.90.850.10 81 303 3.3E-69 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS23485 740eba42af61dd5db7bcce2744c0da2c 316 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 97 302 3.0E-60 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS03495 ca7629bbc29d35ac147bab7eebc0d5ce 326 PIRSF PIRSF017082 2 326 6.0E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03495 ca7629bbc29d35ac147bab7eebc0d5ce 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 7.1E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03495 ca7629bbc29d35ac147bab7eebc0d5ce 326 SUPERFAMILY SSF53850 109 284 4.24E-9 T 06-07-2017 CAL12_RS20360 3a997def4ad79e9dfc96629e379832f9 118 SUPERFAMILY SSF102712 42 85 6.8E-6 T 06-07-2017 CAL12_RS20360 3a997def4ad79e9dfc96629e379832f9 118 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 66 71 - T 06-07-2017 IPR020891 Uncharacterised protein family UPF0758, conserved site CAL12_RS20360 3a997def4ad79e9dfc96629e379832f9 118 Gene3D G3DSA:3.40.140.10 33 117 2.4E-28 T 06-07-2017 CAL12_RS20360 3a997def4ad79e9dfc96629e379832f9 118 Pfam PF04002 RadC-like JAB domain 38 114 9.4E-27 T 06-07-2017 IPR025657 RadC-like JAB domain CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 SUPERFAMILY SSF53335 173 229 2.04E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 SUPERFAMILY SSF53335 1 59 2.04E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 SUPERFAMILY SSF53335 282 319 2.04E-17 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 Gene3D G3DSA:3.40.50.150 191 226 5.5E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 Gene3D G3DSA:3.40.50.150 287 335 5.5E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 Gene3D G3DSA:3.40.50.150 2 59 5.5E-21 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS20305 40c504540d5ef9ada31535f207d438d6 384 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 216 221 - T 06-07-2017 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 KEGG: 00860+2.1.1.11|MetaCyc: PWY-5531|MetaCyc: PWY-7159 CAL12_RS17585 b4534cc8f6d07254bd955d9ee262aa07 414 Gene3D G3DSA:3.90.1150.10 275 410 9.7E-42 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS17585 b4534cc8f6d07254bd955d9ee262aa07 414 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 408 9.4E-103 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS17585 b4534cc8f6d07254bd955d9ee262aa07 414 SUPERFAMILY SSF53383 5 409 1.28E-86 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS17585 b4534cc8f6d07254bd955d9ee262aa07 414 Gene3D G3DSA:3.40.640.10 5 269 9.3E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS17585 b4534cc8f6d07254bd955d9ee262aa07 414 PIRSF PIRSF001434 1 412 6.1E-116 T 06-07-2017 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CAL12_RS20685 9708613c27d647159f83df97bccf1bcb 240 PIRSF PIRSF015736 1 240 2.6E-54 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS21985 abd79f896ef58af01fa101309f320c57 463 Pfam PF03729 Short repeat of unknown function (DUF308) 101 147 1.7E-4 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAL12_RS01725 9650773194804392b60cbbf5430253a6 265 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 69 210 9.9E-25 T 06-07-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CAL12_RS01725 9650773194804392b60cbbf5430253a6 265 Pfam PF03968 OstA-like protein 70 187 9.3E-21 T 06-07-2017 IPR005653 Organic solvent tolerance-like, N-terminal CAL12_RS01725 9650773194804392b60cbbf5430253a6 265 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 11 211 20.763 T 06-07-2017 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 CAL12_RS01725 9650773194804392b60cbbf5430253a6 265 Gene3D G3DSA:2.60.450.10 61 207 1.5E-27 T 06-07-2017 CAL12_RS16905 9f2af6efbb8caf1e490d876124690025 255 Gene3D G3DSA:1.10.10.60 151 185 1.4E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16905 9f2af6efbb8caf1e490d876124690025 255 Gene3D G3DSA:1.10.10.60 186 235 7.9E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS16905 9f2af6efbb8caf1e490d876124690025 255 Pfam PF12833 Helix-turn-helix domain 156 232 4.5E-18 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16905 9f2af6efbb8caf1e490d876124690025 255 SMART SM00342 149 233 1.5E-9 T 06-07-2017 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CAL12_RS16905 9f2af6efbb8caf1e490d876124690025 255 SUPERFAMILY SSF46689 186 235 3.32E-5 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS03975 7a70d9d5b6be7086ba5fc19eb8eb3d5a 142 Pfam PF12680 SnoaL-like domain 13 113 4.9E-13 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS03975 7a70d9d5b6be7086ba5fc19eb8eb3d5a 142 Gene3D G3DSA:3.10.450.50 9 126 1.4E-25 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS03975 7a70d9d5b6be7086ba5fc19eb8eb3d5a 142 SUPERFAMILY SSF54427 10 124 3.56E-24 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS17555 d9614befe6a0d296ab6bec42d640d462 292 Pfam PF01618 MotA/TolQ/ExbB proton channel family 139 254 2.6E-34 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAL12_RS11325 1c8d0bb7fd5ff4fbb7749b4a75546eac 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 133 7.3E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS08035 92d230a75ae67a1a104ab934fd8b1b3d 396 Pfam PF01594 Domain of unknown function DUF20 52 383 4.9E-40 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAL12_RS15515 5c4c6bf196da0b23e92daa0468eaaa28 330 SUPERFAMILY SSF103025 15 243 5.81E-47 T 06-07-2017 CAL12_RS15515 5c4c6bf196da0b23e92daa0468eaaa28 330 Gene3D G3DSA:3.30.70.1400 20 110 5.9E-25 T 06-07-2017 CAL12_RS15515 5c4c6bf196da0b23e92daa0468eaaa28 330 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 188 249 1.9E-25 T 06-07-2017 IPR017703 YgfZ/GcvT conserved site CAL12_RS05995 457d507952ba401cd828329e027f3aae 286 SUPERFAMILY SSF52540 43 284 6.39E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05995 457d507952ba401cd828329e027f3aae 286 Pfam PF00005 ABC transporter 59 214 5.3E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05995 457d507952ba401cd828329e027f3aae 286 Gene3D G3DSA:3.40.50.300 42 283 2.4E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05995 457d507952ba401cd828329e027f3aae 286 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 264 285 9.8E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS05995 457d507952ba401cd828329e027f3aae 286 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 43 286 2.2E-115 T 06-07-2017 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 Gene3D G3DSA:3.90.1180.10 3 141 5.4E-64 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 SUPERFAMILY SSF52161 1 139 1.7E-59 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 Pfam PF00572 Ribosomal protein L13 14 138 1.1E-55 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.356 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 1.7E-61 T 06-07-2017 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS24750 7c396e0d70783900f4d150c5485efe8f 142 PIRSF PIRSF002181 1 142 7.7E-49 T 06-07-2017 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CAL12_RS14080 edb6f035e9cb4e09cd4930ca2d9899a0 225 Pfam PF11769 Protein of unknown function (DUF3313) 15 211 2.1E-52 T 06-07-2017 IPR021747 Protein of unknown function DUF3313 CAL12_RS01870 3869a9c85358e1b501cc569571b10eb8 481 Pfam PF03972 MmgE/PrpD family 26 463 5.0E-116 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS01870 3869a9c85358e1b501cc569571b10eb8 481 SUPERFAMILY SSF103378 22 471 8.11E-115 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS01870 3869a9c85358e1b501cc569571b10eb8 481 Gene3D G3DSA:3.30.1330.120 287 421 5.6E-28 T 06-07-2017 CAL12_RS01450 e0598b9ee472baff2d321f29ef9f19b8 329 PIRSF PIRSF017082 1 329 4.4E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01450 e0598b9ee472baff2d321f29ef9f19b8 329 SUPERFAMILY SSF53850 100 289 4.16E-11 T 06-07-2017 CAL12_RS01450 e0598b9ee472baff2d321f29ef9f19b8 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 1.7E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12040 3de861950c34d51700009f2c510b6b7a 274 Pfam PF07317 Flagellar regulator YcgR 10 122 1.4E-16 T 06-07-2017 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal CAL12_RS12040 3de861950c34d51700009f2c510b6b7a 274 Gene3D G3DSA:2.40.10.220 126 269 3.4E-10 T 06-07-2017 CAL12_RS09890 23af16e65edcbdf1fe04f59e63b87d8a 447 Pfam PF07287 Protein of unknown function (DUF1446) 86 301 8.6E-21 T 06-07-2017 IPR010839 Protein of unknown function DUF1446 CAL12_RS15250 5afc48402100e36988671728399ba070 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.9E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15250 5afc48402100e36988671728399ba070 322 SUPERFAMILY SSF53850 114 275 2.17E-8 T 06-07-2017 CAL12_RS15250 5afc48402100e36988671728399ba070 322 PIRSF PIRSF017082 1 321 3.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19105 9036de60a35aa83db2abb9be98390c95 160 Pfam PF08909 Domain of unknown function (DUF1854) 32 159 6.3E-51 T 06-07-2017 IPR015005 Domain of unknown function DUF1854 CAL12_RS06085 35e1a6ac273a181840104f3c8a390d98 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 1.7E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06085 35e1a6ac273a181840104f3c8a390d98 326 SUPERFAMILY SSF53850 113 286 5.76E-11 T 06-07-2017 CAL12_RS06085 35e1a6ac273a181840104f3c8a390d98 326 PIRSF PIRSF017082 1 324 7.7E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24065 d9585f694812fb0b759193181560829d 77 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 69 5.0E-22 T 06-07-2017 IPR024530 Putative quorum-sensing-regulated virulence factor CAL12_RS24065 d9585f694812fb0b759193181560829d 77 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 3 67 1.9E-30 T 06-07-2017 IPR024530 Putative quorum-sensing-regulated virulence factor CAL12_RS16535 b4accdf61c9783e6cbb43939d36a1aac 460 Gene3D G3DSA:3.40.640.10 83 348 8.6E-83 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS16535 b4accdf61c9783e6cbb43939d36a1aac 460 Gene3D G3DSA:3.90.1150.10 349 452 3.5E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS16535 b4accdf61c9783e6cbb43939d36a1aac 460 SUPERFAMILY SSF53383 4 453 6.42E-111 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS16535 b4accdf61c9783e6cbb43939d36a1aac 460 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 85 390 6.3E-43 T 06-07-2017 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CAL12_RS18690 ef1807ec05f21d0beb29587c67254cd2 313 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 25 292 5.4E-101 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CAL12_RS18690 ef1807ec05f21d0beb29587c67254cd2 313 Pfam PF07848 PaaX-like protein 22 90 3.5E-29 T 06-07-2017 IPR012906 PaaX-like, N-terminal CAL12_RS18690 ef1807ec05f21d0beb29587c67254cd2 313 Pfam PF08223 PaaX-like protein C-terminal domain 108 279 8.6E-54 T 06-07-2017 IPR013225 PaaX-like, C-terminal CAL12_RS18690 ef1807ec05f21d0beb29587c67254cd2 313 PIRSF PIRSF020623 4 312 2.4E-106 T 06-07-2017 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 SUPERFAMILY SSF51735 118 284 3.4E-42 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 2.5E-8 T 06-07-2017 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 Pfam PF00107 Zinc-binding dehydrogenase 158 270 1.4E-24 T 06-07-2017 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 SMART SM00829 11 327 1.6E-37 T 06-07-2017 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 Gene3D G3DSA:3.40.50.720 152 267 1.2E-25 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 SUPERFAMILY SSF50129 2 151 4.09E-32 T 06-07-2017 IPR011032 GroES-like CAL12_RS03550 dfa40f75517e6aca2503eeafbfc1bfec 330 Gene3D G3DSA:3.90.180.10 2 151 1.3E-34 T 06-07-2017 IPR011032 GroES-like CAL12_RS01465 256178bde84bff8dd406a127de078965 257 SMART SM00346 10 98 6.7E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS01465 256178bde84bff8dd406a127de078965 257 SUPERFAMILY SSF46785 10 80 3.22E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01465 256178bde84bff8dd406a127de078965 257 Gene3D G3DSA:1.10.10.10 3 69 6.2E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS01465 256178bde84bff8dd406a127de078965 257 Pfam PF01614 Bacterial transcriptional regulator 127 250 5.9E-30 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS01465 256178bde84bff8dd406a127de078965 257 Pfam PF09339 IclR helix-turn-helix domain 14 63 2.4E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS01465 256178bde84bff8dd406a127de078965 257 Gene3D G3DSA:3.30.450.40 74 252 9.7E-48 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS01465 256178bde84bff8dd406a127de078965 257 SUPERFAMILY SSF55781 74 251 1.77E-42 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13365 5a189c408f172b86c8ef698ef3f865c8 382 Gene3D G3DSA:3.20.20.80 223 367 1.8E-29 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS13365 5a189c408f172b86c8ef698ef3f865c8 382 Gene3D G3DSA:3.20.20.80 30 191 1.8E-29 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS13365 5a189c408f172b86c8ef698ef3f865c8 382 SUPERFAMILY SSF51445 18 348 1.18E-48 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 Gene3D G3DSA:3.20.20.140 84 333 1.2E-39 T 06-07-2017 CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 Gene3D G3DSA:3.20.20.140 23 51 1.2E-39 T 06-07-2017 CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 Pfam PF04909 Amidohydrolase 106 308 3.2E-11 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 SUPERFAMILY SSF51556 397 482 2.04E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 SUPERFAMILY SSF51556 81 327 2.04E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS07320 81f5f166610f9ffdd0c0312116eb47c8 507 SUPERFAMILY SSF51556 23 52 2.04E-37 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS23105 1b0c44818d8d4e6ae12fbed986769fc9 421 Gene3D G3DSA:1.10.357.10 221 359 2.6E-4 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS23105 1b0c44818d8d4e6ae12fbed986769fc9 421 Pfam PF04286 Protein of unknown function (DUF445) 35 407 2.5E-95 T 06-07-2017 IPR007383 Protein of unknown function DUF445 CAL12_RS09625 33b82490e859650343c320d048ff6499 126 Pfam PF09842 Predicted membrane protein (DUF2069) 14 114 1.3E-32 T 06-07-2017 IPR018643 Protein of unknown function DUF2069, membrane CAL12_RS03240 6bd20a0678180f2a24f9dc458096cf36 162 Pfam PF01575 MaoC like domain 27 139 4.8E-22 T 06-07-2017 IPR002539 MaoC-like domain CAL12_RS03240 6bd20a0678180f2a24f9dc458096cf36 162 Gene3D G3DSA:3.10.129.10 22 160 1.1E-37 T 06-07-2017 IPR029069 HotDog domain CAL12_RS03240 6bd20a0678180f2a24f9dc458096cf36 162 SUPERFAMILY SSF54637 23 160 3.88E-35 T 06-07-2017 IPR029069 HotDog domain CAL12_RS26525 f5e8b6479480f45a06949584a4f8fcfb 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 309 2.3E-71 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS26525 f5e8b6479480f45a06949584a4f8fcfb 338 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 37 291 5.7E-72 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS26525 f5e8b6479480f45a06949584a4f8fcfb 338 PIRSF PIRSF006470 3 333 1.4E-74 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS06125 dc0973eede5458a56280f2deaa3af48b 98 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 82 1.2E-35 T 06-07-2017 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CAL12_RS10170 e1d4e6ec48aa9b84457569768b1c887b 141 Pfam PF13279 Thioesterase-like superfamily 19 131 2.3E-9 T 06-07-2017 CAL12_RS10170 e1d4e6ec48aa9b84457569768b1c887b 141 Gene3D G3DSA:3.10.129.10 9 134 3.2E-34 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10170 e1d4e6ec48aa9b84457569768b1c887b 141 SUPERFAMILY SSF54637 9 137 3.23E-33 T 06-07-2017 IPR029069 HotDog domain CAL12_RS14860 d81b884969841b72a5aef8a78dbc96ba 257 SUPERFAMILY SSF52096 3 246 6.4E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14860 d81b884969841b72a5aef8a78dbc96ba 257 Gene3D G3DSA:3.90.226.10 4 245 5.3E-58 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14860 d81b884969841b72a5aef8a78dbc96ba 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 244 5.2E-41 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS15920 6258aa31941315cb739f0bcd8e5ddfba 503 PIRSF PIRSF002741 14 502 1.0E-102 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS15920 6258aa31941315cb739f0bcd8e5ddfba 503 SUPERFAMILY SSF53850 23 500 4.35E-132 T 06-07-2017 CAL12_RS15920 6258aa31941315cb739f0bcd8e5ddfba 503 Gene3D G3DSA:3.10.105.10 281 473 7.2E-55 T 06-07-2017 CAL12_RS15920 6258aa31941315cb739f0bcd8e5ddfba 503 Gene3D G3DSA:3.40.190.10 125 280 7.6E-44 T 06-07-2017 CAL12_RS15920 6258aa31941315cb739f0bcd8e5ddfba 503 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 422 1.9E-85 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS18710 3819b0b017abf36914ba338015484cef 247 SUPERFAMILY SSF55811 72 229 6.5E-34 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS18710 3819b0b017abf36914ba338015484cef 247 Gene3D G3DSA:3.90.79.10 76 236 1.7E-38 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS18710 3819b0b017abf36914ba338015484cef 247 Pfam PF00293 NUDIX domain 79 160 1.2E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS21445 37650ff9dee4a778599c27067a23350c 701 Gene3D G3DSA:2.40.50.100 532 554 4.1E-5 T 06-07-2017 CAL12_RS21445 37650ff9dee4a778599c27067a23350c 701 Gene3D G3DSA:2.40.50.100 442 478 4.1E-5 T 06-07-2017 CAL12_RS21445 37650ff9dee4a778599c27067a23350c 701 Pfam PF13533 Biotin-lipoyl like 452 491 2.0E-5 T 06-07-2017 CAL12_RS21445 37650ff9dee4a778599c27067a23350c 701 Pfam PF13437 HlyD family secretion protein 542 619 8.8E-5 T 06-07-2017 CAL12_RS21445 37650ff9dee4a778599c27067a23350c 701 SUPERFAMILY SSF111369 451 560 7.59E-5 T 06-07-2017 CAL12_RS23995 c00c877156eea365f2caf4e4b0aa8d78 307 SUPERFAMILY SSF103481 67 154 1.18E-6 T 06-07-2017 CAL12_RS23995 c00c877156eea365f2caf4e4b0aa8d78 307 SUPERFAMILY SSF103481 200 296 7.85E-9 T 06-07-2017 CAL12_RS23995 c00c877156eea365f2caf4e4b0aa8d78 307 Pfam PF00892 EamA-like transporter family 164 296 1.0E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS23995 c00c877156eea365f2caf4e4b0aa8d78 307 Pfam PF00892 EamA-like transporter family 23 145 4.8E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS21010 83002d8756126ced2fcb707132dda7a4 177 Pfam PF13827 Domain of unknown function (DUF4189) 76 170 1.1E-18 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 CAL12_RS14605 1892a16c55b20cceec0d031454576459 454 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 74 451 5.1E-113 T 06-07-2017 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 7.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 7.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 7.3E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 Gene3D G3DSA:3.40.50.720 11 241 1.6E-67 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 240 5.3E-48 T 06-07-2017 CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.2E-37 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS13935 6d8d03958ac772f2bfe479326e66dc6b 247 SUPERFAMILY SSF51735 11 241 5.88E-64 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS12990 29455185a3c966a12edd1dff8170fb9e 297 Gene3D G3DSA:1.10.3720.10 93 281 1.6E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12990 29455185a3c966a12edd1dff8170fb9e 297 SUPERFAMILY SSF161098 99 278 1.7E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12990 29455185a3c966a12edd1dff8170fb9e 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 278 1.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14045 f12152cd5a047e1c18393a377a23770d 266 SUPERFAMILY SSF52096 10 254 2.64E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14045 f12152cd5a047e1c18393a377a23770d 266 Gene3D G3DSA:3.90.226.10 11 250 2.7E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14045 f12152cd5a047e1c18393a377a23770d 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 254 2.9E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS17615 83f4813001238e99f593c660e47981d2 314 Pfam PF03547 Membrane transport protein 4 147 2.1E-16 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAL12_RS17615 83f4813001238e99f593c660e47981d2 314 Pfam PF03547 Membrane transport protein 153 302 3.3E-21 T 06-07-2017 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 Gene3D G3DSA:3.80.30.20 36 267 1.2E-31 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 37 379 8.8E-102 T 06-07-2017 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 Pfam PF06969 HemN C-terminal domain 338 399 3.6E-13 T 06-07-2017 IPR010723 HemN, C-terminal CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 SUPERFAMILY SSF102114 33 410 3.66E-109 T 06-07-2017 CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 SMART SM00729 35 251 7.5E-49 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS15325 e349afc748e9b274093d2f5e10177a9a 411 Pfam PF04055 Radical SAM superfamily 40 205 2.0E-16 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS06855 e8181cc492479a867090616ee2a1a1c4 403 SUPERFAMILY SSF53822 30 396 8.44E-69 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS06855 e8181cc492479a867090616ee2a1a1c4 403 Gene3D G3DSA:3.40.50.2300 30 227 1.7E-50 T 06-07-2017 CAL12_RS06855 e8181cc492479a867090616ee2a1a1c4 403 Pfam PF13458 Periplasmic binding protein 32 345 2.5E-54 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS00780 d2247c5a4532102d3634655aebc003be 141 SMART SM00530 6 64 3.6E-11 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS00780 d2247c5a4532102d3634655aebc003be 141 Gene3D G3DSA:1.10.260.40 2 69 9.9E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00780 d2247c5a4532102d3634655aebc003be 141 SUPERFAMILY SSF47413 1 68 6.22E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS00780 d2247c5a4532102d3634655aebc003be 141 Pfam PF13560 Helix-turn-helix domain 4 61 2.6E-8 T 06-07-2017 CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 06-07-2017 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 SUPERFAMILY SSF51735 7 250 9.28E-72 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.8E-41 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 250 9.0E-58 T 06-07-2017 CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 Gene3D G3DSA:3.40.50.720 4 250 1.1E-75 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS03030 59e28aeccb3f22d7e9e310a6a03d2581 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 1.5E-11 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS22930 6f4d2c7444f45f07fc2a5c66701dabc9 148 Pfam PF10696 Protein of unknown function (DUF2501) 71 147 8.4E-24 T 06-07-2017 IPR019637 Protein of unknown function DUF2501 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 Gene3D G3DSA:3.40.190.10 177 262 6.2E-22 T 06-07-2017 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 Gene3D G3DSA:1.10.10.10 5 83 3.0E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 Gene3D G3DSA:3.40.190.10 92 176 1.8E-18 T 06-07-2017 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 Pfam PF03466 LysR substrate binding domain 90 294 1.5E-33 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 SUPERFAMILY SSF46785 4 112 1.55E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 SUPERFAMILY SSF53850 91 299 2.53E-35 T 06-07-2017 CAL12_RS11125 24a7ca471dca339ff101d2377b849ca3 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.3E-17 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 Pfam PF02567 Phenazine biosynthesis-like protein 14 260 3.5E-39 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 Gene3D G3DSA:3.10.310.10 2 113 3.4E-24 T 06-07-2017 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 Gene3D G3DSA:3.10.310.10 123 263 8.8E-32 T 06-07-2017 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 PIRSF PIRSF016184 1 275 8.4E-50 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 13 258 1.3E-37 T 06-07-2017 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CAL12_RS25975 0d0a3255030ea7e3d92a9e5c7cf81d04 275 SUPERFAMILY SSF54506 2 273 5.41E-51 T 06-07-2017 CAL12_RS18360 f84b17fb143b4b9df53fe5a77e5687c6 208 Pfam PF03641 Possible lysine decarboxylase 59 188 3.9E-32 T 06-07-2017 IPR031100 LOG family CAL12_RS18360 f84b17fb143b4b9df53fe5a77e5687c6 208 Gene3D G3DSA:3.40.50.450 4 196 5.7E-61 T 06-07-2017 CAL12_RS18360 f84b17fb143b4b9df53fe5a77e5687c6 208 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 17 189 4.9E-46 T 06-07-2017 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CAL12_RS18360 f84b17fb143b4b9df53fe5a77e5687c6 208 SUPERFAMILY SSF102405 3 189 9.16E-57 T 06-07-2017 CAL12_RS11275 46fa83faf460b28a60e7f4bf5ddfcef2 400 Pfam PF00155 Aminotransferase class I and II 32 391 7.3E-72 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS11275 46fa83faf460b28a60e7f4bf5ddfcef2 400 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 06-07-2017 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CAL12_RS11275 46fa83faf460b28a60e7f4bf5ddfcef2 400 Gene3D G3DSA:3.40.640.10 45 275 5.4E-72 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS11275 46fa83faf460b28a60e7f4bf5ddfcef2 400 SUPERFAMILY SSF53383 3 398 3.5E-108 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS11275 46fa83faf460b28a60e7f4bf5ddfcef2 400 Gene3D G3DSA:3.90.1150.10 276 399 1.6E-40 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS01470 ce27f3c5fd6c4702ae6e44f2f692a625 107 Pfam PF13744 Helix-turn-helix domain 12 85 1.2E-13 T 06-07-2017 CAL12_RS01470 ce27f3c5fd6c4702ae6e44f2f692a625 107 Gene3D G3DSA:1.10.260.40 32 86 4.0E-10 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS01470 ce27f3c5fd6c4702ae6e44f2f692a625 107 SUPERFAMILY SSF47413 24 96 2.82E-13 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS13450 15d053c1fe951727041f11794427ae0d 288 Gene3D G3DSA:1.10.3720.10 75 283 5.7E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13450 15d053c1fe951727041f11794427ae0d 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 286 1.0E-30 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13450 15d053c1fe951727041f11794427ae0d 288 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 62 1.7E-6 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS13450 15d053c1fe951727041f11794427ae0d 288 SUPERFAMILY SSF161098 78 267 1.83E-31 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14150 b678ecc8cfb877b719efe53b552f73e3 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 11 321 4.1E-58 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS14150 b678ecc8cfb877b719efe53b552f73e3 338 Gene3D G3DSA:3.40.50.1100 110 333 9.2E-69 T 06-07-2017 CAL12_RS14150 b678ecc8cfb877b719efe53b552f73e3 338 PIRSF PIRSF006278 1 337 1.6E-110 T 06-07-2017 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CAL12_RS14150 b678ecc8cfb877b719efe53b552f73e3 338 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 11 330 4.2E-98 T 06-07-2017 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 CAL12_RS14150 b678ecc8cfb877b719efe53b552f73e3 338 SUPERFAMILY SSF53686 5 333 6.04E-92 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS13655 721bd2fd51aec414b9f266b977e0c7ce 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 3.8E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13655 721bd2fd51aec414b9f266b977e0c7ce 332 Gene3D G3DSA:3.40.190.10 160 239 1.9E-5 T 06-07-2017 CAL12_RS13655 721bd2fd51aec414b9f266b977e0c7ce 332 PIRSF PIRSF017082 1 332 3.0E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13655 721bd2fd51aec414b9f266b977e0c7ce 332 SUPERFAMILY SSF53850 127 295 1.94E-9 T 06-07-2017 CAL12_RS08605 924a91ea656f59855861bfac683b4452 325 SUPERFAMILY SSF56235 3 155 2.24E-99 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS08605 924a91ea656f59855861bfac683b4452 325 SUPERFAMILY SSF56235 189 320 2.24E-99 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS08605 924a91ea656f59855861bfac683b4452 325 Pfam PF01112 Asparaginase 4 320 2.6E-119 T 06-07-2017 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 CAL12_RS18470 de1abed63f86b8398bc8b2d0125d3bfe 339 SMART SM00062 30 258 0.0024 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS18470 de1abed63f86b8398bc8b2d0125d3bfe 339 Pfam PF09084 NMT1/THI5 like 44 257 1.9E-29 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS18470 de1abed63f86b8398bc8b2d0125d3bfe 339 Gene3D G3DSA:3.40.190.10 124 216 1.8E-21 T 06-07-2017 CAL12_RS18470 de1abed63f86b8398bc8b2d0125d3bfe 339 Gene3D G3DSA:3.40.190.10 253 265 1.8E-21 T 06-07-2017 CAL12_RS18470 de1abed63f86b8398bc8b2d0125d3bfe 339 SUPERFAMILY SSF53850 28 278 9.43E-44 T 06-07-2017 CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Pfam PF02146 Sir2 family 32 234 6.4E-44 T 06-07-2017 IPR003000 Sirtuin family GO:0070403 CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Gene3D G3DSA:3.30.1600.10 130 203 1.6E-20 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Gene3D G3DSA:3.30.1600.10 43 77 1.6E-20 T 06-07-2017 IPR026591 Sirtuin family, catalytic core small domain CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Gene3D G3DSA:3.40.50.1220 92 129 1.0E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Gene3D G3DSA:3.40.50.1220 12 42 1.0E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Gene3D G3DSA:3.40.50.1220 210 280 1.0E-38 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 8 278 59.839 T 06-07-2017 IPR026587 Sirtuin, class II CAL12_RS08040 1270c6e89e3a648e10d38a029ec213ee 296 SUPERFAMILY SSF52467 13 278 4.09E-80 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS18770 a552acf4191781cb644bbe7a75daecff 229 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 8 198 1.5E-49 T 06-07-2017 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 CAL12_RS18770 a552acf4191781cb644bbe7a75daecff 229 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 9 197 2.6E-40 T 06-07-2017 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 SUPERFAMILY SSF56235 51 806 2.83E-167 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 Gene3D G3DSA:1.10.439.10 40 195 2.7E-42 T 06-07-2017 IPR023343 Penicillin amidase type, domain1 GO:0016811 CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 Pfam PF01804 Penicillin amidase 56 794 9.5E-131 T 06-07-2017 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 Gene3D G3DSA:3.60.20.10 426 628 1.2E-69 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 Gene3D G3DSA:3.60.20.10 274 353 1.2E-69 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 PIRSF PIRSF001227 13 800 1.8E-142 T 06-07-2017 IPR014395 Penicillin acylase GO:0016811 CAL12_RS01840 57466f248b84efc13f2712f670d9e33d 807 Gene3D G3DSA:2.30.120.10 354 404 2.0E-9 T 06-07-2017 CAL12_RS24580 478f557fc40202efcb28066e15592fc1 343 SUPERFAMILY SSF53850 133 308 1.45E-14 T 06-07-2017 CAL12_RS24580 478f557fc40202efcb28066e15592fc1 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 68 338 5.3E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24580 478f557fc40202efcb28066e15592fc1 343 PIRSF PIRSF017082 12 342 6.0E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17790 7abfc2066a7b787332edcc616c264cbc 275 Pfam PF00795 Carbon-nitrogen hydrolase 13 264 1.2E-53 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS17790 7abfc2066a7b787332edcc616c264cbc 275 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 160 180 - T 06-07-2017 IPR001110 Uncharacterised protein family UPF0012, conserved site CAL12_RS17790 7abfc2066a7b787332edcc616c264cbc 275 Gene3D G3DSA:3.60.110.10 5 273 7.6E-83 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS17790 7abfc2066a7b787332edcc616c264cbc 275 SUPERFAMILY SSF56317 9 273 4.06E-80 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS14445 5a74461e6ba0e1536aa8f49c25bcd749 319 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 284 5.4E-49 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS14445 5a74461e6ba0e1536aa8f49c25bcd749 319 Gene3D G3DSA:3.40.50.720 105 285 2.0E-54 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS14445 5a74461e6ba0e1536aa8f49c25bcd749 319 SUPERFAMILY SSF51735 106 285 1.06E-49 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Pfam PF03466 LysR substrate binding domain 95 295 2.0E-40 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Gene3D G3DSA:1.10.10.10 10 85 6.9E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 SUPERFAMILY SSF46785 9 118 2.3E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Gene3D G3DSA:3.40.190.10 95 176 2.8E-7 T 06-07-2017 CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Gene3D G3DSA:3.40.190.10 282 296 2.8E-7 T 06-07-2017 CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Gene3D G3DSA:3.40.190.10 177 264 1.1E-21 T 06-07-2017 CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 8.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS03775 b57bf37456c0e1daadd4ad2a4d8097e6 297 SUPERFAMILY SSF53850 96 296 3.44E-44 T 06-07-2017 CAL12_RS15005 c5a0e1210798e5968c7d29e07b5e3bc1 602 Pfam PF00860 Permease family 37 416 5.9E-42 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS09855 0851e6bfdd111ca22b882ce470eb8dfd 36 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 26 8.1E-15 T 06-07-2017 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 CAL12_RS09855 0851e6bfdd111ca22b882ce470eb8dfd 36 Pfam PF08173 Membrane bound YbgT-like protein 1 26 4.4E-15 T 06-07-2017 IPR012994 Membrane bound YbgT-like CAL12_RS02900 f0bfaaa65aade9a67f726e4fd5858cb1 385 Pfam PF12698 ABC-2 family transporter protein 37 373 8.8E-40 T 06-07-2017 CAL12_RS23610 1fbd9838fa548a05626cf0891a789554 357 Pfam PF03773 Predicted permease 80 344 1.4E-22 T 06-07-2017 IPR005524 Predicted permease DUF318 CAL12_RS10645 1f800bfdd7861d1c1c651dfb0166bbcb 346 Gene3D G3DSA:3.40.190.10 151 258 2.4E-5 T 06-07-2017 CAL12_RS10645 1f800bfdd7861d1c1c651dfb0166bbcb 346 PIRSF PIRSF017082 10 345 6.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10645 1f800bfdd7861d1c1c651dfb0166bbcb 346 SUPERFAMILY SSF53850 143 314 1.93E-14 T 06-07-2017 CAL12_RS10645 1f800bfdd7861d1c1c651dfb0166bbcb 346 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 341 5.5E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08530 0ad3409328df0aa2aa4072ffc1055d57 205 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 106 182 2.6E-8 T 06-07-2017 IPR007621 TPM domain CAL12_RS24320 33986792449666e0b3032666988603dc 519 Gene3D G3DSA:3.90.1300.10 55 517 1.7E-133 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24320 33986792449666e0b3032666988603dc 519 SUPERFAMILY SSF75304 56 517 1.24E-128 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24320 33986792449666e0b3032666988603dc 519 Pfam PF01425 Amidase 78 500 9.4E-103 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS11025 0c13ccd27a85d87e254a27109ae0475c 75 SMART SM00923 3 53 2.9E-25 T 06-07-2017 IPR005153 MbtH-like protein CAL12_RS11025 0c13ccd27a85d87e254a27109ae0475c 75 Gene3D G3DSA:3.90.820.10 13 70 1.7E-31 T 06-07-2017 CAL12_RS11025 0c13ccd27a85d87e254a27109ae0475c 75 SUPERFAMILY SSF160582 2 70 4.84E-29 T 06-07-2017 CAL12_RS11025 0c13ccd27a85d87e254a27109ae0475c 75 Pfam PF03621 MbtH-like protein 3 53 7.3E-23 T 06-07-2017 IPR005153 MbtH-like protein CAL12_RS04890 fef2ffbe9ac14873b0f4c9a64ccbdcb3 304 SUPERFAMILY SSF63829 22 297 2.62E-46 T 06-07-2017 CAL12_RS04890 fef2ffbe9ac14873b0f4c9a64ccbdcb3 304 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 36 274 6.1E-36 T 06-07-2017 IPR013658 SMP-30/Gluconolactonase/LRE-like region CAL12_RS04890 fef2ffbe9ac14873b0f4c9a64ccbdcb3 304 Gene3D G3DSA:2.120.10.30 26 297 4.2E-48 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS00095 55af8ea2ef21e03dbd9d1669b3997f90 139 SUPERFAMILY SSF54427 9 131 1.43E-16 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS00095 55af8ea2ef21e03dbd9d1669b3997f90 139 Pfam PF13577 SnoaL-like domain 8 128 2.2E-10 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS00095 55af8ea2ef21e03dbd9d1669b3997f90 139 Gene3D G3DSA:3.10.450.50 12 131 1.2E-11 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS27865 7eae25452b5e108cc86ee9a3b176e5a8 388 Gene3D G3DSA:3.90.1150.10 273 385 6.6E-18 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS27865 7eae25452b5e108cc86ee9a3b176e5a8 388 SUPERFAMILY SSF53383 3 385 8.16E-101 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS27865 7eae25452b5e108cc86ee9a3b176e5a8 388 Gene3D G3DSA:3.40.640.10 38 272 1.7E-71 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS27865 7eae25452b5e108cc86ee9a3b176e5a8 388 Pfam PF00155 Aminotransferase class I and II 26 385 3.8E-58 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS16010 52488140e77114818d886d8264637a57 157 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 14 156 4.6E-36 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CAL12_RS16010 52488140e77114818d886d8264637a57 157 Gene3D G3DSA:3.30.479.10 12 156 1.9E-40 T 06-07-2017 CAL12_RS16010 52488140e77114818d886d8264637a57 157 SUPERFAMILY SSF55620 12 156 5.56E-40 T 06-07-2017 CAL12_RS16010 52488140e77114818d886d8264637a57 157 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 14 127 4.8E-28 T 06-07-2017 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 26 328 3.5E-9 T 06-07-2017 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 SUPERFAMILY SSF51735 112 298 3.84E-48 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 Gene3D G3DSA:3.40.50.720 9 120 3.4E-18 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 Gene3D G3DSA:3.40.50.720 121 298 1.4E-51 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 SUPERFAMILY SSF52283 9 132 4.46E-17 T 06-07-2017 CAL12_RS04715 ddee0f1a730ff7d7c511f743486ce1c7 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 297 7.8E-49 T 06-07-2017 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CAL12_RS15110 39f76c7b5ae33a4d04bb71585ddd4e31 673 Pfam PF02538 Hydantoinase B/oxoprolinase 4 529 4.9E-139 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS22565 c2e5af71de15d1c0d540aa512c248d98 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 145 5.1E-24 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 SMART SM00346 8 96 8.2E-8 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 SUPERFAMILY SSF55781 80 245 3.07E-33 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 Pfam PF09339 IclR helix-turn-helix domain 12 59 5.4E-11 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 Pfam PF01614 Bacterial transcriptional regulator 125 242 7.7E-11 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 Gene3D G3DSA:1.10.10.10 7 74 2.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 SUPERFAMILY SSF46785 10 76 4.0E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11250 05b625421c5c5079c591b73aa278166e 247 Gene3D G3DSA:3.30.450.40 75 238 2.3E-38 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS00980 8eaea0738226fcb3f76d688f39149d74 594 Pfam PF00920 Dehydratase family 44 571 3.4E-151 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS00980 8eaea0738226fcb3f76d688f39149d74 594 SUPERFAMILY SSF52016 381 578 1.41E-45 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS00980 8eaea0738226fcb3f76d688f39149d74 594 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 127 137 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS00980 8eaea0738226fcb3f76d688f39149d74 594 SUPERFAMILY SSF143975 6 378 3.79E-114 T 06-07-2017 CAL12_RS19335 967d4b64f3d9b872a46bca3a385d7b28 142 SUPERFAMILY SSF54427 35 130 3.68E-32 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS19335 967d4b64f3d9b872a46bca3a385d7b28 142 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 8 132 27.181 T 06-07-2017 IPR023006 Uncharacterised protein family UPF0225 CAL12_RS19335 967d4b64f3d9b872a46bca3a385d7b28 142 Gene3D G3DSA:3.10.450.50 11 131 1.2E-40 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS12485 730cf0414f72c32ec9b6bca62601ec71 429 SUPERFAMILY SSF53822 43 403 5.89E-68 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS12485 730cf0414f72c32ec9b6bca62601ec71 429 Pfam PF13458 Periplasmic binding protein 43 386 3.8E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS12485 730cf0414f72c32ec9b6bca62601ec71 429 Gene3D G3DSA:3.40.50.2300 43 239 3.8E-39 T 06-07-2017 CAL12_RS22630 8de872cb3a815705d3e703cd8dbc3122 162 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 138 2.7E-25 T 06-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CAL12_RS22630 8de872cb3a815705d3e703cd8dbc3122 162 TIGRFAM TIGR02801 tolR: protein TolR 15 137 1.1E-37 T 06-07-2017 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 Gene3D G3DSA:1.10.10.10 84 160 1.4E-32 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 Gene3D G3DSA:1.10.10.10 1 81 5.6E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 SUPERFAMILY SSF46785 2 82 2.04E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 14 170 1.8E-29 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 SUPERFAMILY SSF46785 85 160 6.23E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18450 dd66a35b944ad1ee44de56b4a2f2cee6 373 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 169 3.8E-46 T 06-07-2017 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CAL12_RS19055 c71eef2081ecf6bd0abb7ded4ebc7f64 185 Pfam PF01584 CheW-like domain 25 159 3.3E-14 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS19055 c71eef2081ecf6bd0abb7ded4ebc7f64 185 SUPERFAMILY SSF50341 24 162 1.31E-18 T 06-07-2017 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CAL12_RS12645 05930589a649875e4bd2020e588af3d0 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 217 8.4E-73 T 06-07-2017 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CAL12_RS12645 05930589a649875e4bd2020e588af3d0 225 SUPERFAMILY SSF161098 8 217 8.24E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12645 05930589a649875e4bd2020e588af3d0 225 Gene3D G3DSA:1.10.3720.10 8 217 6.0E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS12645 05930589a649875e4bd2020e588af3d0 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 213 1.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27845 e28bac349c8cf059183240a58751fc06 266 Gene3D G3DSA:3.40.50.300 12 263 1.1E-70 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27845 e28bac349c8cf059183240a58751fc06 266 SUPERFAMILY SSF52540 10 262 5.98E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27845 e28bac349c8cf059183240a58751fc06 266 Pfam PF13614 AAA domain 11 186 1.4E-65 T 06-07-2017 IPR025669 AAA domain CAL12_RS06760 96ca74d791845f900b6eb6dd30f6ace6 118 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 10 113 6.2E-28 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAL12_RS06760 96ca74d791845f900b6eb6dd30f6ace6 118 Pfam PF13806 Rieske-like [2Fe-2S] domain 10 113 2.1E-33 T 06-07-2017 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CAL12_RS06760 96ca74d791845f900b6eb6dd30f6ace6 118 SUPERFAMILY SSF50022 9 115 3.4E-30 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS06760 96ca74d791845f900b6eb6dd30f6ace6 118 Gene3D G3DSA:2.102.10.10 10 114 2.1E-34 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS11540 09f1eaf596357503a5cf39f6570c71da 181 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 111 177 1.0E-5 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11540 09f1eaf596357503a5cf39f6570c71da 181 Pfam PF05345 Putative Ig domain 1 38 4.9E-5 T 06-07-2017 IPR008009 Putative Ig CAL12_RS11540 09f1eaf596357503a5cf39f6570c71da 181 Gene3D G3DSA:2.60.40.670 23 54 4.4E-4 T 06-07-2017 IPR000601 PKD domain CAL12_RS02490 2e619a6b3c3bbb6875e1c4335d7e7749 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 276 6.2E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02490 2e619a6b3c3bbb6875e1c4335d7e7749 292 Gene3D G3DSA:1.10.3720.10 94 287 2.5E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02490 2e619a6b3c3bbb6875e1c4335d7e7749 292 SUPERFAMILY SSF161098 94 277 9.16E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13605 c155b295d08c47712ebd1dc610c73b7c 328 PIRSF PIRSF017082 1 327 4.9E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13605 c155b295d08c47712ebd1dc610c73b7c 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 319 3.7E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13605 c155b295d08c47712ebd1dc610c73b7c 328 SUPERFAMILY SSF53850 124 282 4.78E-10 T 06-07-2017 CAL12_RS27560 e1aa934d8f7e3a42d5714dadcb4f242b 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.3E-26 T 06-07-2017 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27560 e1aa934d8f7e3a42d5714dadcb4f242b 101 SUPERFAMILY SSF57716 2 101 6.7E-38 T 06-07-2017 CAL12_RS27560 e1aa934d8f7e3a42d5714dadcb4f242b 101 Gene3D G3DSA:4.10.830.10 41 101 9.9E-31 T 06-07-2017 CAL12_RS27560 e1aa934d8f7e3a42d5714dadcb4f242b 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.147 T 06-07-2017 IPR023036 Ribosomal protein S14, bacterial/plastid CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:3.20.20.80 4 96 7.3E-75 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:3.20.20.80 692 816 7.3E-75 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:3.20.20.80 257 342 7.3E-75 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:3.20.20.80 534 574 7.3E-75 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 897 1.2E-283 T 06-07-2017 IPR012767 Malto-oligosyltrehalose synthase MetaCyc: PWY-2661 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:3.30.1590.10 97 241 4.1E-41 T 06-07-2017 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 SUPERFAMILY SSF51445 484 784 4.16E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 SUPERFAMILY SSF51445 4 444 4.16E-130 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 SMART SM00642 14 448 2.2E-8 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Pfam PF00128 Alpha amylase, catalytic domain 23 118 1.4E-16 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:1.10.10.470 575 676 2.1E-24 T 06-07-2017 IPR013797 Maltooligosyl trehalose synthase, N-terminal MetaCyc: PWY-2661 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:1.10.150.200 473 500 5.0E-5 T 06-07-2017 CAL12_RS16175 9be2acfec98bab25da8b5dc4ec608875 899 Gene3D G3DSA:1.10.150.200 408 428 5.0E-5 T 06-07-2017 CAL12_RS11495 4cdd3da9fd2118b675f0b934cccaddf7 131 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 131 8.5E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11355 99140880dee81f9ffd2233717a06dfc3 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 3.5E-30 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS13685 4ead1c2529d13566c22f5e89e474811c 315 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 311 2.0E-53 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13685 4ead1c2529d13566c22f5e89e474811c 315 SUPERFAMILY SSF53850 109 221 1.45E-7 T 06-07-2017 CAL12_RS13685 4ead1c2529d13566c22f5e89e474811c 315 SUPERFAMILY SSF53850 40 64 1.45E-7 T 06-07-2017 CAL12_RS13685 4ead1c2529d13566c22f5e89e474811c 315 PIRSF PIRSF017082 1 315 1.3E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03075 5c29d771e043d306c63f2a43db2c0069 293 Gene3D G3DSA:3.40.50.1820 29 282 1.5E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03075 5c29d771e043d306c63f2a43db2c0069 293 SUPERFAMILY SSF53474 29 279 1.36E-20 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03075 5c29d771e043d306c63f2a43db2c0069 293 Pfam PF10503 Esterase PHB depolymerase 35 161 2.4E-6 T 06-07-2017 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CAL12_RS05635 f56b3292013943afe43a8523d3ab38a7 342 Pfam PF02608 Basic membrane protein 34 278 1.1E-31 T 06-07-2017 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CAL12_RS05635 f56b3292013943afe43a8523d3ab38a7 342 SUPERFAMILY SSF53822 41 241 9.76E-10 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS05635 f56b3292013943afe43a8523d3ab38a7 342 Gene3D G3DSA:3.40.50.2300 31 152 1.8E-29 T 06-07-2017 CAL12_RS05635 f56b3292013943afe43a8523d3ab38a7 342 Gene3D G3DSA:3.40.50.2300 153 287 7.0E-24 T 06-07-2017 CAL12_RS07695 1d51cbed42a99501dfb4acb1673d9aa9 330 PIRSF PIRSF017082 4 327 1.4E-61 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07695 1d51cbed42a99501dfb4acb1673d9aa9 330 SUPERFAMILY SSF53850 116 286 5.43E-7 T 06-07-2017 CAL12_RS07695 1d51cbed42a99501dfb4acb1673d9aa9 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 320 5.6E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23180 3357ce49b24d189a6c9e33c744163a93 499 PIRSF PIRSF012702 1 496 9.1E-167 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS23180 3357ce49b24d189a6c9e33c744163a93 499 Pfam PF07364 Metallopeptidase family M81 2 285 3.1E-97 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS23180 3357ce49b24d189a6c9e33c744163a93 499 Pfam PF07171 MlrC C-terminus 298 479 7.8E-55 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS24770 1149eae1bb3fdb4095cb7e53650bdcbc 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 6.9E-51 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS24655 895661a272c5fcc9bf9ae98cb962d7f2 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 283 2.6E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24655 895661a272c5fcc9bf9ae98cb962d7f2 287 Gene3D G3DSA:1.10.3720.10 81 283 2.7E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24655 895661a272c5fcc9bf9ae98cb962d7f2 287 SUPERFAMILY SSF161098 83 270 1.31E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05710 35d8bcc8895d3313c334b456f615db27 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 9 105 1.4E-19 T 06-07-2017 IPR008407 Branched-chain amino acid transport, AzlD CAL12_RS04690 01ac87f6b3df61a4ee1cdcfcf3542208 135 SUPERFAMILY SSF54593 3 119 2.96E-21 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS04690 01ac87f6b3df61a4ee1cdcfcf3542208 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 115 2.5E-5 T 06-07-2017 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CAL12_RS04690 01ac87f6b3df61a4ee1cdcfcf3542208 135 PIRSF PIRSF039020 1 121 3.7E-46 T 06-07-2017 IPR026275 Glyoxalase/bleomycin resistance protein/dioxygenase CAL12_RS04690 01ac87f6b3df61a4ee1cdcfcf3542208 135 Gene3D G3DSA:3.10.180.10 5 118 3.1E-20 T 06-07-2017 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CAL12_RS11200 45491f1435d83b5bb1bfa639ce3af793 536 SUPERFAMILY SSF51905 1 226 9.5E-53 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11200 45491f1435d83b5bb1bfa639ce3af793 536 Gene3D G3DSA:3.50.50.60 1 214 8.0E-63 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11200 45491f1435d83b5bb1bfa639ce3af793 536 Gene3D G3DSA:3.50.50.60 344 521 3.3E-17 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS11200 45491f1435d83b5bb1bfa639ce3af793 536 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 1 202 4.7E-17 T 06-07-2017 CAL12_RS11200 45491f1435d83b5bb1bfa639ce3af793 536 SUPERFAMILY SSF51905 309 523 1.55E-24 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS24475 6220f165f1805db7aa0efd731e543451 257 Pfam PF02633 Creatinine amidohydrolase 1 242 4.3E-60 T 06-07-2017 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAL12_RS24475 6220f165f1805db7aa0efd731e543451 257 SUPERFAMILY SSF102215 2 246 7.19E-63 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAL12_RS24475 6220f165f1805db7aa0efd731e543451 257 Gene3D G3DSA:3.40.50.10310 1 247 3.2E-70 T 06-07-2017 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CAL12_RS06955 d9c5aabf1f6b8c67f7b27215cf37010a 380 Gene3D G3DSA:3.40.190.10 182 297 1.4E-5 T 06-07-2017 CAL12_RS06955 d9c5aabf1f6b8c67f7b27215cf37010a 380 SUPERFAMILY SSF53850 167 342 5.72E-17 T 06-07-2017 CAL12_RS06955 d9c5aabf1f6b8c67f7b27215cf37010a 380 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 104 376 2.0E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10640 67822cf170f855604be4e84265460587 458 Gene3D G3DSA:3.30.1330.120 277 409 1.4E-20 T 06-07-2017 CAL12_RS10640 67822cf170f855604be4e84265460587 458 SUPERFAMILY SSF103378 3 443 3.66E-92 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS10640 67822cf170f855604be4e84265460587 458 Pfam PF03972 MmgE/PrpD family 8 432 4.5E-95 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS07295 40bda609a434392990631ea896ed7a90 71 Gene3D G3DSA:2.40.50.100 6 69 9.3E-23 T 06-07-2017 CAL12_RS07295 40bda609a434392990631ea896ed7a90 71 SUPERFAMILY SSF50331 6 69 8.99E-17 T 06-07-2017 IPR008995 Molybdate/tungstate binding, C-terminal CAL12_RS07295 40bda609a434392990631ea896ed7a90 71 Pfam PF03459 TOBE domain 8 67 5.4E-16 T 06-07-2017 IPR005116 Transport-associated OB, type 1 CAL12_RS07295 40bda609a434392990631ea896ed7a90 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 5 69 7.2E-19 T 06-07-2017 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 CAL12_RS16035 852e33156cc13de64a90b86b21adf27c 118 Gene3D G3DSA:1.10.10.10 50 102 5.5E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16035 852e33156cc13de64a90b86b21adf27c 118 SUPERFAMILY SSF46785 33 100 4.04E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16035 852e33156cc13de64a90b86b21adf27c 118 Pfam PF01047 MarR family 53 99 2.9E-9 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS21940 32a65dca63f725765e121633b2e4e9e0 448 PRINTS PR00164 ABC-2 type transport system membrane protein signature 367 386 2.8E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS21940 32a65dca63f725765e121633b2e4e9e0 448 PRINTS PR00164 ABC-2 type transport system membrane protein signature 330 354 2.8E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS21940 32a65dca63f725765e121633b2e4e9e0 448 PRINTS PR00164 ABC-2 type transport system membrane protein signature 387 406 2.8E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS21940 32a65dca63f725765e121633b2e4e9e0 448 PRINTS PR00164 ABC-2 type transport system membrane protein signature 222 243 2.8E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS21940 32a65dca63f725765e121633b2e4e9e0 448 Pfam PF01061 ABC-2 type transporter 209 410 1.5E-8 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAL12_RS03880 0e7e9ef86fde03c7fa2be1ffae827531 290 SUPERFAMILY SSF51556 18 289 3.12E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS03880 0e7e9ef86fde03c7fa2be1ffae827531 290 Gene3D G3DSA:3.20.20.140 3 289 8.1E-82 T 06-07-2017 CAL12_RS03880 0e7e9ef86fde03c7fa2be1ffae827531 290 Pfam PF04909 Amidohydrolase 24 288 3.2E-31 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS09090 b6ee345803bb0f291cf275031d01d778 182 Gene3D G3DSA:3.40.630.30 21 178 1.9E-66 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS09090 b6ee345803bb0f291cf275031d01d778 182 Pfam PF00583 Acetyltransferase (GNAT) family 73 142 5.8E-9 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS09090 b6ee345803bb0f291cf275031d01d778 182 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 22 177 8.3E-64 T 06-07-2017 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CAL12_RS09090 b6ee345803bb0f291cf275031d01d778 182 SUPERFAMILY SSF55729 22 142 2.3E-18 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS22710 7412ff1aeba9a0b73d8857a86329dccd 174 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 12 163 2.2E-21 T 06-07-2017 IPR017737 Type VI secretion system, lysozyme-related protein CAL12_RS22710 7412ff1aeba9a0b73d8857a86329dccd 174 Gene3D G3DSA:3.10.450.40 80 145 9.3E-4 T 06-07-2017 CAL12_RS22710 7412ff1aeba9a0b73d8857a86329dccd 174 SUPERFAMILY SSF160719 80 155 4.97E-8 T 06-07-2017 CAL12_RS22710 7412ff1aeba9a0b73d8857a86329dccd 174 Pfam PF04965 Gene 25-like lysozyme 39 145 2.2E-18 T 06-07-2017 IPR007048 GpW/Gp25/anti-adapter protein IraD CAL12_RS14275 6fb7f40dff95057c654c6dfb2d583f8a 324 PIRSF PIRSF017082 1 323 3.5E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14275 6fb7f40dff95057c654c6dfb2d583f8a 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 9.4E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14275 6fb7f40dff95057c654c6dfb2d583f8a 324 SUPERFAMILY SSF53850 114 284 5.43E-11 T 06-07-2017 CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 SUPERFAMILY SSF53448 356 601 2.77E-51 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 Gene3D G3DSA:3.90.550.10 105 316 1.8E-52 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 Gene3D G3DSA:3.90.550.10 363 624 7.6E-53 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 Pfam PF00535 Glycosyl transferase family 2 366 544 2.0E-22 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 Pfam PF00535 Glycosyl transferase family 2 108 239 3.5E-24 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS26995 9fca85e4db8635e1c6447eaff8c23d2a 651 SUPERFAMILY SSF53448 105 314 1.13E-49 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS01015 0b002c614e650a805d280ada3b8bc89b 258 Pfam PF02104 SURF1 family 16 231 9.2E-29 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 Pfam PF00831 Ribosomal L29 protein 4 60 7.8E-21 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 SUPERFAMILY SSF46561 1 61 1.44E-19 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.097 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 06-07-2017 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 Gene3D G3DSA:1.10.287.310 1 60 4.0E-24 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS27615 f76dd27ffa98d507827c24e6c0a0bacb 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 8.6E-20 T 06-07-2017 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CAL12_RS20585 ec881225850356825022f1f2dda3bf01 427 Pfam PF06666 Protein of unknown function (DUF1173) 19 410 1.3E-95 T 06-07-2017 IPR009553 Protein of unknown function DUF1173 CAL12_RS03490 f925d9d4b368545061f80177d8a60764 144 Gene3D G3DSA:3.10.450.50 8 121 2.1E-14 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS03490 f925d9d4b368545061f80177d8a60764 144 Pfam PF12680 SnoaL-like domain 13 126 4.9E-14 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS03490 f925d9d4b368545061f80177d8a60764 144 SUPERFAMILY SSF54427 7 131 1.1E-21 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS14130 1198aac028045cd638efb807f29a23d7 140 Pfam PF00582 Universal stress protein family 98 140 5.3E-10 T 06-07-2017 IPR006016 UspA GO:0006950 CAL12_RS14130 1198aac028045cd638efb807f29a23d7 140 Gene3D G3DSA:3.40.50.620 98 140 2.0E-12 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS14130 1198aac028045cd638efb807f29a23d7 140 SUPERFAMILY SSF52402 58 140 1.09E-14 T 06-07-2017 CAL12_RS25020 52f9762d45868c1bf94005aea9f8fccc 124 Pfam PF09345 Domain of unknown function (DUF1987) 13 111 3.6E-36 T 06-07-2017 IPR018530 Domain of unknown function DUF1987 CAL12_RS03130 368622cf9f48dfee0cf8dcdc5f101361 280 Gene3D G3DSA:3.60.130.10 3 280 5.7E-87 T 06-07-2017 CAL12_RS03130 368622cf9f48dfee0cf8dcdc5f101361 280 SUPERFAMILY SSF51197 5 280 1.33E-83 T 06-07-2017 CAL12_RS03130 368622cf9f48dfee0cf8dcdc5f101361 280 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 6 272 5.2E-60 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS16585 f75cf7ac55441819a6c7c6680ed68a60 191 Gene3D G3DSA:3.40.1350.10 80 189 3.8E-8 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAL12_RS16585 f75cf7ac55441819a6c7c6680ed68a60 191 Pfam PF04471 Restriction endonuclease 81 186 3.4E-15 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CAL12_RS16585 f75cf7ac55441819a6c7c6680ed68a60 191 SUPERFAMILY SSF52980 83 187 4.4E-6 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 Gene3D G3DSA:1.10.150.240 19 82 1.0E-13 T 06-07-2017 IPR023198 Phosphoglycolate phosphatase, domain 2 CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 Gene3D G3DSA:3.40.50.1000 86 219 8.1E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 Gene3D G3DSA:3.40.50.1000 2 18 8.1E-39 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 SUPERFAMILY SSF56784 2 219 4.58E-50 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 106 186 5.9E-12 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS03630 c65af4b1bb4e606c7014d77b13c1a5ca 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 2.6E-22 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS21945 d9fb47d395f174991956eac241d3cdd8 379 Gene3D G3DSA:3.30.1950.10 83 159 2.0E-15 T 06-07-2017 CAL12_RS21945 d9fb47d395f174991956eac241d3cdd8 379 Gene3D G3DSA:3.10.560.10 161 237 4.0E-11 T 06-07-2017 CAL12_RS21945 d9fb47d395f174991956eac241d3cdd8 379 Pfam PF02563 Polysaccharide biosynthesis/export protein 81 159 3.2E-12 T 06-07-2017 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 CAL12_RS21945 d9fb47d395f174991956eac241d3cdd8 379 Gene3D G3DSA:3.10.560.10 238 339 1.4E-15 T 06-07-2017 CAL12_RS06930 f5f5274bfb6060335b49f6fe28b2c689 60 Gene3D G3DSA:1.10.1470.10 1 56 1.1E-17 T 06-07-2017 IPR008462 CsbD-like CAL12_RS06930 f5f5274bfb6060335b49f6fe28b2c689 60 Pfam PF05532 CsbD-like 4 56 1.0E-15 T 06-07-2017 IPR008462 CsbD-like CAL12_RS06930 f5f5274bfb6060335b49f6fe28b2c689 60 SUPERFAMILY SSF69047 1 57 1.05E-14 T 06-07-2017 IPR008462 CsbD-like CAL12_RS10200 f0962e5fb71a0dee50e6069ff5b3e2c9 90 Gene3D G3DSA:1.10.1200.10 1 85 2.1E-20 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS10200 f0962e5fb71a0dee50e6069ff5b3e2c9 90 SUPERFAMILY SSF47336 1 84 5.23E-14 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS10200 f0962e5fb71a0dee50e6069ff5b3e2c9 90 Pfam PF00550 Phosphopantetheine attachment site 7 79 1.4E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.3E-6 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 SUPERFAMILY SSF46689 2 82 1.03E-15 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.8E-11 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 SUPERFAMILY SSF48498 80 187 6.68E-28 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 Gene3D G3DSA:1.10.357.10 58 187 3.0E-37 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS12745 ac071cbb25cc8294983898fd4c96db5f 202 Gene3D G3DSA:1.10.10.60 1 57 3.2E-18 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS22545 761055a40b405d9b9e0300b9d358ac5b 227 Pfam PF04402 Protein of unknown function (DUF541) 28 223 1.4E-24 T 06-07-2017 IPR007497 Protein of unknown function DUF541 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 PRINTS PR00127 Clp protease catalytic subunit P signature 40 55 1.0E-52 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 PRINTS PR00127 Clp protease catalytic subunit P signature 111 128 1.0E-52 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 PRINTS PR00127 Clp protease catalytic subunit P signature 132 151 1.0E-52 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 PRINTS PR00127 Clp protease catalytic subunit P signature 189 208 1.0E-52 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 PRINTS PR00127 Clp protease catalytic subunit P signature 80 100 1.0E-52 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 24 212 1.5E-103 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 133 146 - T 06-07-2017 IPR033135 ClpP, histidine active site CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 Gene3D G3DSA:3.90.226.10 24 212 1.5E-88 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 SUPERFAMILY SSF52096 32 214 1.04E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 24 214 44.772 T 06-07-2017 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CAL12_RS17215 fde0048a78ec7763eb8cc2ae1f0f37d1 218 Pfam PF00574 Clp protease 34 213 8.4E-88 T 06-07-2017 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CAL12_RS10325 2f293906ee3b6473e147c8f59e458f38 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 1.6E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10325 2f293906ee3b6473e147c8f59e458f38 324 SUPERFAMILY SSF53850 110 285 1.14E-8 T 06-07-2017 CAL12_RS10325 2f293906ee3b6473e147c8f59e458f38 324 PIRSF PIRSF017082 1 323 4.8E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 Pfam PF01738 Dienelactone hydrolase family 69 179 1.0E-7 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 SUPERFAMILY SSF53474 46 175 2.38E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 SUPERFAMILY SSF53474 225 304 2.38E-23 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 Gene3D G3DSA:3.40.50.1820 10 175 9.7E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 Gene3D G3DSA:3.40.50.1820 225 333 9.7E-35 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS21095 6e30e4bd2fa929b38cad99f679d782be 337 PIRSF PIRSF031982 1 337 4.2E-80 T 06-07-2017 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL CAL12_RS10250 7df9afbd648cfe54dc74e9add5490ea7 321 SUPERFAMILY SSF48452 4 106 1.21E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS10250 7df9afbd648cfe54dc74e9add5490ea7 321 Pfam PF14559 Tetratricopeptide repeat 27 82 7.2E-7 T 06-07-2017 CAL12_RS10250 7df9afbd648cfe54dc74e9add5490ea7 321 Gene3D G3DSA:1.25.40.10 24 86 8.8E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 SUPERFAMILY SSF53850 98 304 1.81E-40 T 06-07-2017 CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 Gene3D G3DSA:1.10.10.10 6 89 5.2E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 SUPERFAMILY SSF46785 5 88 5.44E-16 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 69 7.7E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 Pfam PF03466 LysR substrate binding domain 98 300 6.4E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS10535 8aca4797c4f55887ae4e1022952668ff 311 Gene3D G3DSA:3.40.190.10 99 196 1.8E-32 T 06-07-2017 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 SUPERFAMILY SSF53822 21 369 2.86E-100 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 Gene3D G3DSA:3.40.50.2300 299 350 2.7E-54 T 06-07-2017 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 Gene3D G3DSA:3.40.50.2300 16 145 2.7E-54 T 06-07-2017 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 278 291 1.1E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 44 60 1.1E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 22 38 1.1E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 63 81 1.1E-10 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 Gene3D G3DSA:3.40.50.2300 146 298 1.5E-23 T 06-07-2017 CAL12_RS03330 18df33e1284775bdd34eb8d914b8bc60 385 Pfam PF13458 Periplasmic binding protein 21 363 2.5E-85 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS10510 459f1eef0cf3f2add9893f81892d5be0 149 Pfam PF02627 Carboxymuconolactone decarboxylase family 11 95 5.4E-15 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS10510 459f1eef0cf3f2add9893f81892d5be0 149 Gene3D G3DSA:1.20.1290.10 2 145 5.0E-47 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS10510 459f1eef0cf3f2add9893f81892d5be0 149 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 76 3.8E-13 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS10510 459f1eef0cf3f2add9893f81892d5be0 149 SUPERFAMILY SSF69118 2 145 6.34E-42 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 195 206 - T 06-07-2017 IPR020845 AMP-binding, conserved site CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 525 4.0E-14 T 06-07-2017 IPR025110 AMP-binding enzyme C-terminal domain CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Gene3D G3DSA:3.30.300.30 432 533 3.2E-24 T 06-07-2017 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 SUPERFAMILY SSF56801 25 544 1.7E-129 T 06-07-2017 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Gene3D G3DSA:2.30.38.10 356 428 2.6E-24 T 06-07-2017 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Gene3D G3DSA:3.40.50.980 26 200 1.5E-39 T 06-07-2017 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Pfam PF00501 AMP-binding enzyme 33 437 4.5E-86 T 06-07-2017 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CAL12_RS02360 06f512b08098d025fe12ac6ceae34c75 551 Gene3D G3DSA:3.40.50.980 201 349 2.3E-23 T 06-07-2017 CAL12_RS10045 a24d980eb824acf5a1f396ec61306592 396 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 119 387 3.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10045 a24d980eb824acf5a1f396ec61306592 396 SUPERFAMILY SSF53850 185 353 5.43E-8 T 06-07-2017 CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 140 4.1E-7 T 06-07-2017 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 Pfam PF13378 Enolase C-terminal domain-like 163 364 1.1E-29 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 SUPERFAMILY SSF54826 24 141 3.7E-20 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 SUPERFAMILY SSF51604 148 364 9.43E-41 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 Gene3D G3DSA:3.20.20.120 146 364 9.8E-44 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 SMART SM00922 160 257 8.6E-16 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS24575 8052af7b05cade22cc07f94c4a309066 384 Gene3D G3DSA:3.30.390.10 24 145 8.5E-24 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS12915 98fb4d71ce2f4884aa56c734257db74a 313 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 2 309 5.0E-31 T 06-07-2017 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 SUPERFAMILY SSF52540 5 222 8.04E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 SMART SM00382 30 217 1.2E-12 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 Gene3D G3DSA:3.40.50.300 274 487 1.7E-40 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 Gene3D G3DSA:3.40.50.300 2 232 1.8E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 Pfam PF00005 ABC transporter 22 170 6.6E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 Pfam PF00005 ABC transporter 277 430 1.3E-17 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS05630 b4962467a675e5c8d3eb1a4f6f10f093 516 SUPERFAMILY SSF52540 275 488 2.98E-37 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS21005 3d3a555f3f87c53f83c58f55e290cf20 181 Pfam PF13827 Domain of unknown function (DUF4189) 80 174 1.2E-21 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 CAL12_RS20720 9664acd98110eeded4160f432ec632e6 337 SUPERFAMILY SSF89733 5 336 4.45E-98 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS20720 9664acd98110eeded4160f432ec632e6 337 Gene3D G3DSA:3.30.1370.60 76 277 6.9E-78 T 06-07-2017 CAL12_RS20720 9664acd98110eeded4160f432ec632e6 337 Gene3D G3DSA:1.10.1530.10 7 75 7.2E-18 T 06-07-2017 CAL12_RS20720 9664acd98110eeded4160f432ec632e6 337 Pfam PF02615 Malate/L-lactate dehydrogenase 8 332 2.5E-96 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS17180 20c6499f8e471d3b0b333bbf7914c024 184 Gene3D G3DSA:1.10.10.10 1 141 2.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17180 20c6499f8e471d3b0b333bbf7914c024 184 Pfam PF02082 Transcriptional regulator 1 83 3.6E-27 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAL12_RS17180 20c6499f8e471d3b0b333bbf7914c024 184 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 139 2.4E-63 T 06-07-2017 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 CAL12_RS17180 20c6499f8e471d3b0b333bbf7914c024 184 SUPERFAMILY SSF46785 2 137 5.16E-34 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS17180 20c6499f8e471d3b0b333bbf7914c024 184 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 3.2E-42 T 06-07-2017 IPR000944 Transcription regulator Rrf2-type CAL12_RS07985 19f6f049a545beacc86a8e350f9dae8a 443 Pfam PF01943 Polysaccharide biosynthesis protein 15 290 3.5E-12 T 06-07-2017 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CAL12_RS10705 11f587d330be73d6a38580754a683aaa 147 Pfam PF03653 Uncharacterised protein family (UPF0093) 4 147 1.1E-12 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS10705 11f587d330be73d6a38580754a683aaa 147 PIRSF PIRSF004638 1 147 5.8E-20 T 06-07-2017 IPR005265 Uncharacterised protein family UPF0093 CAL12_RS24765 f374e6f7ec775bfa512b38ba2807937d 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 263 8.6E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS13170 c54e057066b9e977dfbba12b827bb6e2 394 Pfam PF02417 Chromate transporter 223 387 2.9E-31 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS13170 c54e057066b9e977dfbba12b827bb6e2 394 Pfam PF02417 Chromate transporter 6 170 6.9E-33 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS13170 c54e057066b9e977dfbba12b827bb6e2 394 TIGRFAM TIGR00937 2A51: chromate efflux transporter 11 387 8.5E-96 T 06-07-2017 IPR014047 Chromate transporter, long chain CAL12_RS13170 c54e057066b9e977dfbba12b827bb6e2 394 PIRSF PIRSF004810 1 394 6.0E-117 T 06-07-2017 IPR014047 Chromate transporter, long chain CAL12_RS10245 aa10d33934d98a47015c9184d9803b48 234 PIRSF PIRSF037290 1 215 3.3E-79 T 06-07-2017 IPR017166 Uncharacterised conserved protein UCP037290 CAL12_RS10245 aa10d33934d98a47015c9184d9803b48 234 Gene3D G3DSA:3.40.50.300 45 158 3.3E-38 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10245 aa10d33934d98a47015c9184d9803b48 234 SUPERFAMILY SSF52540 44 157 2.34E-30 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS23850 e7172a202a1e15d65bd0d5b6b999d127 418 Pfam PF02661 Fic/DOC family 116 226 9.0E-18 T 06-07-2017 IPR003812 Fido domain CAL12_RS23850 e7172a202a1e15d65bd0d5b6b999d127 418 SUPERFAMILY SSF140931 111 294 2.88E-29 T 06-07-2017 IPR003812 Fido domain CAL12_RS23850 e7172a202a1e15d65bd0d5b6b999d127 418 Gene3D G3DSA:1.10.3290.10 45 297 5.1E-41 T 06-07-2017 IPR003812 Fido domain CAL12_RS12815 ce51a0e347eafeee7b127d57d63cc2ff 320 SUPERFAMILY SSF51556 10 320 1.41E-85 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS12815 ce51a0e347eafeee7b127d57d63cc2ff 320 Gene3D G3DSA:3.20.20.140 6 320 3.2E-92 T 06-07-2017 CAL12_RS12815 ce51a0e347eafeee7b127d57d63cc2ff 320 Pfam PF04909 Amidohydrolase 42 320 4.7E-50 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS24645 c0af21f758cb2d19a269ddda49f6daf9 197 Gene3D G3DSA:3.40.50.850 4 193 8.1E-43 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS24645 c0af21f758cb2d19a269ddda49f6daf9 197 Pfam PF00857 Isochorismatase family 7 189 1.4E-36 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS24645 c0af21f758cb2d19a269ddda49f6daf9 197 SUPERFAMILY SSF52499 5 194 1.02E-39 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 SUPERFAMILY SSF46785 4 115 8.16E-18 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.3E-16 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 Gene3D G3DSA:3.40.190.10 95 180 6.9E-15 T 06-07-2017 CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 Gene3D G3DSA:3.40.190.10 181 270 5.7E-32 T 06-07-2017 CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 SUPERFAMILY SSF53850 94 301 2.79E-34 T 06-07-2017 CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 Gene3D G3DSA:1.10.10.10 4 83 6.5E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS14500 434553e7aa6680f194756dbe76faf9a5 325 Pfam PF03466 LysR substrate binding domain 92 296 1.3E-31 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 44.487 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 Pfam PF00920 Dehydratase family 34 610 1.3E-214 T 06-07-2017 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 2.4E-247 T 06-07-2017 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 SUPERFAMILY SSF143975 3 423 4.05E-130 T 06-07-2017 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 06-07-2017 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CAL12_RS01890 d269b66f83b6be731aa325395da61713 620 SUPERFAMILY SSF52016 424 616 8.63E-60 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS19030 f10b248dec6bf0fa20c132070dd9ecf2 335 SUPERFAMILY SSF89733 2 333 1.96E-101 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS19030 f10b248dec6bf0fa20c132070dd9ecf2 335 Gene3D G3DSA:1.10.1530.10 4 72 4.9E-19 T 06-07-2017 CAL12_RS19030 f10b248dec6bf0fa20c132070dd9ecf2 335 Gene3D G3DSA:3.30.1370.60 73 273 9.3E-75 T 06-07-2017 CAL12_RS19030 f10b248dec6bf0fa20c132070dd9ecf2 335 Pfam PF02615 Malate/L-lactate dehydrogenase 5 328 7.6E-104 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS20355 a5aa50855a305cb5ecd01cc6bd52b7ef 107 ProDom PD012854 PLASMID KLCA ANTIRESTRICTION YFJX YCIB ARDB STABLE YFEB Z1216 C0275 18 107 3.0E-16 T 06-07-2017 IPR004914 Antirestriction protein CAL12_RS20355 a5aa50855a305cb5ecd01cc6bd52b7ef 107 Pfam PF03230 Antirestriction protein 17 107 2.6E-31 T 06-07-2017 IPR004914 Antirestriction protein CAL12_RS14865 cfda1e9e51ea6b79349cf1fe4f364f43 427 Gene3D G3DSA:3.40.50.10540 2 218 6.5E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14865 cfda1e9e51ea6b79349cf1fe4f364f43 427 Gene3D G3DSA:3.40.50.10540 308 398 6.5E-89 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14865 cfda1e9e51ea6b79349cf1fe4f364f43 427 SUPERFAMILY SSF89796 2 397 2.09E-95 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14865 cfda1e9e51ea6b79349cf1fe4f364f43 427 Pfam PF02515 CoA-transferase family III 5 376 4.3E-85 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS14865 cfda1e9e51ea6b79349cf1fe4f364f43 427 Gene3D G3DSA:3.30.1540.10 256 307 1.7E-10 T 06-07-2017 CAL12_RS14670 8d5cf9ca61cafc5badc6c85e79e0753c 328 SUPERFAMILY SSF53850 115 287 6.21E-11 T 06-07-2017 CAL12_RS14670 8d5cf9ca61cafc5badc6c85e79e0753c 328 PIRSF PIRSF017082 1 325 1.2E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14670 8d5cf9ca61cafc5badc6c85e79e0753c 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 3.0E-68 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15010 407f424cf063059ba58f8fd791f1b0f1 135 Gene3D G3DSA:3.90.1590.10 1 134 1.0E-40 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAL12_RS15010 407f424cf063059ba58f8fd791f1b0f1 135 SUPERFAMILY SSF51316 1 135 1.67E-43 T 06-07-2017 IPR011057 Mss4-like CAL12_RS15010 407f424cf063059ba58f8fd791f1b0f1 135 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 25 116 7.0E-24 T 06-07-2017 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 CAL12_RS19825 4283689acf326ff076499ff3f2f21363 347 SUPERFAMILY SSF53850 133 298 4.1E-10 T 06-07-2017 CAL12_RS19825 4283689acf326ff076499ff3f2f21363 347 PIRSF PIRSF017082 15 346 3.5E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19825 4283689acf326ff076499ff3f2f21363 347 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 70 343 2.9E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06270 4967fa7d66d305f6514ee0a38c8bd56f 181 Pfam PF01292 Prokaryotic cytochrome b561 14 181 2.8E-23 T 06-07-2017 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 CAL12_RS06270 4967fa7d66d305f6514ee0a38c8bd56f 181 SUPERFAMILY SSF81342 12 181 2.67E-25 T 06-07-2017 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CAL12_RS17055 b376110eb220b9420633ed72ebe87907 182 Pfam PF07209 Protein of unknown function (DUF1415) 9 176 2.5E-67 T 06-07-2017 IPR009858 Protein of unknown function DUF1415 CAL12_RS27265 001616ebb846366f131acc8c839d76ad 460 Pfam PF03972 MmgE/PrpD family 28 439 1.5E-76 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27265 001616ebb846366f131acc8c839d76ad 460 SUPERFAMILY SSF103378 26 457 7.19E-75 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS27265 001616ebb846366f131acc8c839d76ad 460 Gene3D G3DSA:3.30.1330.120 282 384 2.4E-13 T 06-07-2017 CAL12_RS20460 21280f144ccaf5a600a2c89c73448761 159 Pfam PF14499 Domain of unknown function (DUF4437) 63 135 1.4E-10 T 06-07-2017 IPR028013 Protein of unknown function DUF4437 CAL12_RS20460 21280f144ccaf5a600a2c89c73448761 159 Gene3D G3DSA:2.60.120.10 56 149 2.9E-18 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS20460 21280f144ccaf5a600a2c89c73448761 159 SUPERFAMILY SSF51182 38 150 4.72E-13 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS05935 06403118c3bb789456a606cf0e7e1d33 165 SUPERFAMILY SSF89562 3 156 3.79E-42 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS05935 06403118c3bb789456a606cf0e7e1d33 165 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 153 4.8E-49 T 06-07-2017 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 CAL12_RS05935 06403118c3bb789456a606cf0e7e1d33 165 Pfam PF03737 Demethylmenaquinone methyltransferase 5 153 5.3E-39 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS05935 06403118c3bb789456a606cf0e7e1d33 165 Gene3D G3DSA:3.50.30.40 2 153 2.2E-44 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS08630 82a0438c37f68ede3190ca4df36f0e10 385 Pfam PF03576 Peptidase family S58 28 366 5.5E-109 T 06-07-2017 IPR005321 Peptidase S58, DmpA CAL12_RS08630 82a0438c37f68ede3190ca4df36f0e10 385 SUPERFAMILY SSF56266 22 381 2.28E-95 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS08630 82a0438c37f68ede3190ca4df36f0e10 385 Gene3D G3DSA:3.60.70.12 16 372 4.6E-124 T 06-07-2017 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CAL12_RS01455 448a4bc8cf0ecdb0057acd570cf78a0b 144 SUPERFAMILY SSF54637 3 143 6.28E-35 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01455 448a4bc8cf0ecdb0057acd570cf78a0b 144 Gene3D G3DSA:3.10.129.10 3 143 6.6E-36 T 06-07-2017 IPR029069 HotDog domain CAL12_RS01455 448a4bc8cf0ecdb0057acd570cf78a0b 144 Pfam PF01575 MaoC like domain 11 122 6.0E-16 T 06-07-2017 IPR002539 MaoC-like domain CAL12_RS20215 1cbb46ed50e2eb93cf5c2f042508a0a2 804 SUPERFAMILY SSF52540 386 728 5.85E-31 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20215 1cbb46ed50e2eb93cf5c2f042508a0a2 804 TIGRFAM TIGR00929 VirB4_CagE: type IV secretion/conjugal transfer ATPase, VirB4 family 2 797 1.4E-199 T 06-07-2017 IPR004346 CagE, TrbE, VirB component of type IV transporter system GO:0005524 CAL12_RS20215 1cbb46ed50e2eb93cf5c2f042508a0a2 804 Gene3D G3DSA:3.40.50.300 642 718 2.7E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20215 1cbb46ed50e2eb93cf5c2f042508a0a2 804 Gene3D G3DSA:3.40.50.300 441 559 2.7E-9 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20215 1cbb46ed50e2eb93cf5c2f042508a0a2 804 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 185 379 1.2E-28 T 06-07-2017 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 PIRSF PIRSF001338 10 169 2.9E-60 T 06-07-2017 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 SMART SM01001 13 164 6.6E-91 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 Gene3D G3DSA:3.40.50.7700 8 166 4.7E-68 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 15 166 1.4E-59 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 SUPERFAMILY SSF52255 14 168 1.7E-60 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 15 168 29.983 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS05225 805f97c31a19e6084f1d8de114110847 176 Pfam PF00731 AIR carboxylase 15 162 6.3E-59 T 06-07-2017 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CAL12_RS24910 40c43bda9a5d622c88b3fcc11ff77b7d 364 Pfam PF13416 Bacterial extracellular solute-binding protein 62 321 1.2E-20 T 06-07-2017 CAL12_RS24910 40c43bda9a5d622c88b3fcc11ff77b7d 364 SUPERFAMILY SSF53850 42 355 8.24E-57 T 06-07-2017 CAL12_RS24910 40c43bda9a5d622c88b3fcc11ff77b7d 364 Gene3D G3DSA:3.40.190.10 144 284 8.8E-58 T 06-07-2017 CAL12_RS24910 40c43bda9a5d622c88b3fcc11ff77b7d 364 Gene3D G3DSA:3.40.190.10 7 143 2.9E-59 T 06-07-2017 CAL12_RS24910 40c43bda9a5d622c88b3fcc11ff77b7d 364 Gene3D G3DSA:3.40.190.10 285 359 2.9E-59 T 06-07-2017 CAL12_RS07860 47597332e28ba97ec86506b7df0f26fe 356 SUPERFAMILY SSF53850 126 307 3.2E-5 T 06-07-2017 CAL12_RS07860 47597332e28ba97ec86506b7df0f26fe 356 PIRSF PIRSF017082 20 356 9.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07860 47597332e28ba97ec86506b7df0f26fe 356 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 77 346 3.1E-53 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07425 218f2c28dc01393c71ca83a24c8e6868 326 SUPERFAMILY SSF53850 117 287 6.7E-12 T 06-07-2017 CAL12_RS07425 218f2c28dc01393c71ca83a24c8e6868 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 1.3E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07425 218f2c28dc01393c71ca83a24c8e6868 326 PIRSF PIRSF017082 1 326 4.5E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 8.1E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 8.1E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 140 160 8.1E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 8.1E-14 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 SUPERFAMILY SSF46785 30 163 1.04E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 Gene3D G3DSA:1.10.10.10 29 163 4.4E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 SMART SM00347 48 150 2.2E-23 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS26145 00a76b32123a0b460689c70404bc0c4b 165 Pfam PF01047 MarR family 55 115 3.0E-10 T 06-07-2017 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 391 1.4E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 152 1.2E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 SUPERFAMILY SSF161098 191 377 3.01E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 Gene3D G3DSA:1.10.3720.10 88 158 3.4E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 Gene3D G3DSA:1.10.3720.10 263 391 3.4E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25250 f95b5f2eae7d279fd39621b6c570a98d 396 SUPERFAMILY SSF161098 89 156 2.13E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13900 43062e98160a8e809c75a5bf05b988a7 449 TIGRFAM TIGR02035 D_Ser_am_lyase: D-serine ammonia-lyase 14 439 3.4E-150 T 06-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CAL12_RS13900 43062e98160a8e809c75a5bf05b988a7 449 Hamap MF_01030 D-serine dehydratase [dsdA]. 1 449 190.818 T 06-07-2017 IPR011780 D-serine ammonia-lyase GO:0008721|GO:0030170|GO:0046416 KEGG: 00260+4.3.1.18 CAL12_RS13900 43062e98160a8e809c75a5bf05b988a7 449 SUPERFAMILY SSF53686 70 432 1.3E-50 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS13900 43062e98160a8e809c75a5bf05b988a7 449 Gene3D G3DSA:3.40.50.1100 156 428 1.4E-37 T 06-07-2017 CAL12_RS13900 43062e98160a8e809c75a5bf05b988a7 449 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 393 5.7E-47 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 Pfam PF01311 Bacterial export proteins, family 1 15 249 2.4E-52 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 TIGRFAM TIGR01401 fliR_like_III: type III secretion apparatus protein SpaR/YscT/HrcT 10 260 1.7E-72 T 06-07-2017 IPR006304 Type III secretion protein SpaR/YscT GO:0006810|GO:0016021 CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 23 44 4.8E-32 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 84 103 4.8E-32 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 186 208 4.8E-32 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS22045 aebc9278d5c996a55b7ce0749639e646 267 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 208 227 4.8E-32 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS00240 b554869e2ba63095515a829f5a7251a6 257 SUPERFAMILY SSF56524 54 256 9.94E-63 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS00240 b554869e2ba63095515a829f5a7251a6 257 Gene3D G3DSA:3.90.420.10 96 254 2.0E-51 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS00240 b554869e2ba63095515a829f5a7251a6 257 Pfam PF00174 Oxidoreductase molybdopterin binding domain 102 246 1.1E-30 T 06-07-2017 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CAL12_RS06785 85ec020bfa547765f4565671efd70ded 247 PIRSF PIRSF015736 1 243 4.5E-53 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS05575 d5e69ea7ae6226b5e93915ba6a5cdd2c 310 Gene3D G3DSA:3.40.50.720 1 230 2.5E-50 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS05575 d5e69ea7ae6226b5e93915ba6a5cdd2c 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 209 1.2E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS05575 d5e69ea7ae6226b5e93915ba6a5cdd2c 310 SUPERFAMILY SSF51735 1 261 1.08E-52 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.8E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 9.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 9.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 9.0E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 Gene3D G3DSA:1.10.10.10 4 89 3.0E-25 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 Gene3D G3DSA:3.40.190.10 91 201 2.1E-25 T 06-07-2017 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 SUPERFAMILY SSF53850 91 297 3.09E-30 T 06-07-2017 CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 Pfam PF03466 LysR substrate binding domain 91 296 5.2E-30 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS20990 97adbdea2dc9ba33db79efe1dac1d60e 317 SUPERFAMILY SSF46785 4 114 4.03E-22 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 SMART SM00079 30 247 9.6E-6 T 06-07-2017 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 06-07-2017 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 SUPERFAMILY SSF53850 7 246 4.3E-72 T 06-07-2017 CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 246 7.9E-67 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 Gene3D G3DSA:3.40.190.10 209 246 1.4E-43 T 06-07-2017 CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 Gene3D G3DSA:3.40.190.10 28 106 1.4E-43 T 06-07-2017 CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 SMART SM00062 30 247 2.0E-75 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS11245 dfe1a200e6e327061d0964eda30bef08 247 Gene3D G3DSA:3.40.190.10 107 208 1.5E-27 T 06-07-2017 CAL12_RS18615 564be74a24221a137eff498c229ff2b7 332 Pfam PF02401 LytB protein 15 291 2.5E-93 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAL12_RS18615 564be74a24221a137eff498c229ff2b7 332 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 13 295 38.448 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAL12_RS18615 564be74a24221a137eff498c229ff2b7 332 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 15 293 9.2E-101 T 06-07-2017 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 CAL12_RS03225 1f7f4262c5b1e10fe3fa73a9a2ea8667 276 Gene3D G3DSA:3.40.192.10 11 121 3.7E-30 T 06-07-2017 CAL12_RS03225 1f7f4262c5b1e10fe3fa73a9a2ea8667 276 Gene3D G3DSA:3.40.50.720 122 252 8.8E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS03225 1f7f4262c5b1e10fe3fa73a9a2ea8667 276 SUPERFAMILY SSF53223 11 114 2.76E-25 T 06-07-2017 CAL12_RS03225 1f7f4262c5b1e10fe3fa73a9a2ea8667 276 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 19 102 1.3E-19 T 06-07-2017 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CAL12_RS03225 1f7f4262c5b1e10fe3fa73a9a2ea8667 276 SUPERFAMILY SSF51735 116 260 5.15E-31 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS25215 e5490a410dac05ca5562e97d7a3ba7a0 335 PIRSF PIRSF017082 1 335 7.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25215 e5490a410dac05ca5562e97d7a3ba7a0 335 SUPERFAMILY SSF53850 121 293 4.46E-12 T 06-07-2017 CAL12_RS25215 e5490a410dac05ca5562e97d7a3ba7a0 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 329 6.9E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS12625 737f2503e4c364e3996bed3e84eda3bc 322 SUPERFAMILY SSF51412 2 312 1.13E-64 T 06-07-2017 CAL12_RS12625 737f2503e4c364e3996bed3e84eda3bc 322 Pfam PF03060 Nitronate monooxygenase 3 307 1.4E-54 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAL12_RS12625 737f2503e4c364e3996bed3e84eda3bc 322 Gene3D G3DSA:3.20.20.70 2 302 1.5E-67 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS11960 8df2453b8f3881ab959f46a26a06452d 577 Pfam PF00884 Sulfatase 325 511 4.8E-15 T 06-07-2017 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 CAL12_RS11960 8df2453b8f3881ab959f46a26a06452d 577 SUPERFAMILY SSF53649 324 486 4.14E-12 T 06-07-2017 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CAL12_RS11960 8df2453b8f3881ab959f46a26a06452d 577 Gene3D G3DSA:3.40.720.10 310 520 1.1E-6 T 06-07-2017 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CAL12_RS20515 1e955cf06cdc7df23b3316b6c8471b51 322 PIRSF PIRSF017082 1 322 3.0E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20515 1e955cf06cdc7df23b3316b6c8471b51 322 SUPERFAMILY SSF53850 93 280 9.5E-12 T 06-07-2017 CAL12_RS20515 1e955cf06cdc7df23b3316b6c8471b51 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 318 1.0E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25565 260223582ba8a0eaffc06e35800c6541 226 SUPERFAMILY SSF53335 8 189 4.71E-40 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS25565 260223582ba8a0eaffc06e35800c6541 226 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 210 3.3E-33 T 06-07-2017 CAL12_RS25565 260223582ba8a0eaffc06e35800c6541 226 Gene3D G3DSA:3.40.50.150 16 218 5.9E-49 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17935 6f09e50fb64926eb3589dd2406061c1e 186 SUPERFAMILY SSF48452 10 182 4.17E-62 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS17935 6f09e50fb64926eb3589dd2406061c1e 186 Gene3D G3DSA:1.25.40.10 87 185 4.0E-35 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS17935 6f09e50fb64926eb3589dd2406061c1e 186 Gene3D G3DSA:1.20.58.320 10 86 5.1E-31 T 06-07-2017 CAL12_RS17935 6f09e50fb64926eb3589dd2406061c1e 186 Pfam PF06041 Bacterial protein of unknown function (DUF924) 15 183 1.4E-54 T 06-07-2017 IPR010323 Protein of unknown function DUF924 CAL12_RS27685 8b8cf5c50a01f90695b065628f2c5663 431 SUPERFAMILY SSF56112 28 180 3.3E-8 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS27685 8b8cf5c50a01f90695b065628f2c5663 431 Gene3D G3DSA:1.10.510.10 27 188 1.7E-6 T 06-07-2017 CAL12_RS21470 b47fc1f94d649ba6e4fd7fa5baefd180 423 SUPERFAMILY SSF51419 52 263 4.65E-26 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS21470 b47fc1f94d649ba6e4fd7fa5baefd180 423 SMART SM01119 311 410 4.3E-42 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS21470 b47fc1f94d649ba6e4fd7fa5baefd180 423 Pfam PF14031 Putative serine dehydratase domain 311 409 1.2E-16 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS21470 b47fc1f94d649ba6e4fd7fa5baefd180 423 Gene3D G3DSA:3.20.20.10 93 260 2.8E-10 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS21470 b47fc1f94d649ba6e4fd7fa5baefd180 423 Pfam PF01168 Alanine racemase, N-terminal domain 52 252 7.2E-11 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS13240 0f0776fdf5e144bfa95ec1cb5220f9f6 137 Pfam PF03713 Domain of unknown function (DUF305) 26 110 6.1E-21 T 06-07-2017 IPR005183 Domain of unknown function DUF305 CAL12_RS13240 0f0776fdf5e144bfa95ec1cb5220f9f6 137 Gene3D G3DSA:1.20.1260.10 39 112 1.3E-24 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS25920 0dfd429ecfe403a80beb59fc654ec0a3 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 8.1E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25920 0dfd429ecfe403a80beb59fc654ec0a3 324 SUPERFAMILY SSF53850 115 285 9.19E-12 T 06-07-2017 CAL12_RS25920 0dfd429ecfe403a80beb59fc654ec0a3 324 PIRSF PIRSF017082 1 324 5.6E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17580 1009e67e4e93c44d15fe0dc46f45eb78 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 46.921 T 06-07-2017 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 CAL12_RS17580 1009e67e4e93c44d15fe0dc46f45eb78 226 SMART SM00702 1 177 8.4E-27 T 06-07-2017 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CAL12_RS17580 1009e67e4e93c44d15fe0dc46f45eb78 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 1.0E-12 T 06-07-2017 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 51 1.1E-13 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 SUPERFAMILY SSF46689 3 79 1.75E-17 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 Gene3D G3DSA:1.10.357.10 3 177 7.1E-36 T 06-07-2017 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 9.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 9.3E-7 T 06-07-2017 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CAL12_RS27230 6901839d8289d957c494734943e40df2 187 SUPERFAMILY SSF48498 76 180 1.13E-19 T 06-07-2017 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CAL12_RS22720 43dd2f9c3e0d823667d660e584328f7e 500 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 71 495 6.2E-176 T 06-07-2017 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CAL12_RS22720 43dd2f9c3e0d823667d660e584328f7e 500 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 22 495 9.8E-202 T 06-07-2017 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath CAL12_RS15065 8735d8acc8734c79ea9a4ee632057406 98 Gene3D G3DSA:3.10.20.30 10 83 2.3E-6 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS15065 8735d8acc8734c79ea9a4ee632057406 98 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 11 90 4.2E-23 T 06-07-2017 CAL12_RS15065 8735d8acc8734c79ea9a4ee632057406 98 SUPERFAMILY SSF54292 14 90 1.71E-15 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS09790 b386b29b3dbf18c6f653765d5f73a283 355 PIRSF PIRSF017082 26 355 2.2E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS09790 b386b29b3dbf18c6f653765d5f73a283 355 SUPERFAMILY SSF53850 142 314 3.65E-13 T 06-07-2017 CAL12_RS09790 b386b29b3dbf18c6f653765d5f73a283 355 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 80 346 1.6E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 Gene3D G3DSA:3.40.50.300 6 200 8.5E-41 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 Gene3D G3DSA:3.30.1220.10 239 332 7.4E-11 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 SUPERFAMILY SSF52540 6 181 7.91E-20 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 194 1.2E-33 T 06-07-2017 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 SUPERFAMILY SSF90002 252 333 5.36E-9 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS01380 d627e01d0b2b696f390c851d22f790df 345 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 249 332 8.2E-8 T 06-07-2017 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CAL12_RS27985 2c49d1375167e86d91a0c5fae4a37a56 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 5.4E-24 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27985 2c49d1375167e86d91a0c5fae4a37a56 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.832 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27985 2c49d1375167e86d91a0c5fae4a37a56 44 Pfam PF00468 Ribosomal protein L34 1 44 1.9E-22 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS27985 2c49d1375167e86d91a0c5fae4a37a56 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 06-07-2017 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CAL12_RS27985 2c49d1375167e86d91a0c5fae4a37a56 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 2.0E-15 T 06-07-2017 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS05390 d53a97b01113656e8be0b39b93fffc24 172 Gene3D G3DSA:2.30.110.10 5 160 4.4E-50 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS05390 d53a97b01113656e8be0b39b93fffc24 172 SUPERFAMILY SSF50475 13 160 2.06E-41 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS05390 d53a97b01113656e8be0b39b93fffc24 172 Pfam PF01613 Flavin reductase like domain 18 160 5.6E-31 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS05390 d53a97b01113656e8be0b39b93fffc24 172 SMART SM00903 17 162 1.8E-52 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS18410 b539595f2d70eeefa0b14f604ac8512c 329 SUPERFAMILY SSF53850 117 288 4.72E-10 T 06-07-2017 CAL12_RS18410 b539595f2d70eeefa0b14f604ac8512c 329 PIRSF PIRSF017082 1 328 3.6E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18410 b539595f2d70eeefa0b14f604ac8512c 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 326 2.8E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 338 4.6E-21 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 SMART SM00382 58 250 3.3E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 317 2.1E-17 T 06-07-2017 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 SUPERFAMILY SSF52540 22 271 1.52E-72 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 Pfam PF00005 ABC transporter 50 200 3.6E-31 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15095 402309a882b41a0d949ce18dd5519ccc 345 Gene3D G3DSA:3.40.50.300 21 273 3.5E-82 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27285 7143fdc16656139cd0d98d50d624f6ab 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 295 7.7E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 SUPERFAMILY SSF53335 71 252 3.32E-31 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 Pfam PF08242 Methyltransferase domain 87 184 2.7E-10 T 06-07-2017 IPR013217 Methyltransferase type 12 CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 Gene3D G3DSA:3.40.50.2000 932 1084 2.7E-14 T 06-07-2017 CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 SUPERFAMILY SSF53756 778 1111 6.8E-51 T 06-07-2017 CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 Pfam PF00534 Glycosyl transferases group 1 936 1084 6.3E-20 T 06-07-2017 IPR001296 Glycosyl transferase, family 1 CAL12_RS26915 f3bd83ab2e439caf794ddee4bae348e9 1125 Gene3D G3DSA:3.40.50.150 74 253 1.8E-29 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS16575 5b552a3a8195769d207e8480009299ab 407 Pfam PF07690 Major Facilitator Superfamily 31 371 3.8E-36 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS16575 5b552a3a8195769d207e8480009299ab 407 SUPERFAMILY SSF103473 28 400 6.02E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16575 5b552a3a8195769d207e8480009299ab 407 Gene3D G3DSA:1.20.1250.20 222 394 3.1E-11 T 06-07-2017 CAL12_RS16575 5b552a3a8195769d207e8480009299ab 407 Gene3D G3DSA:1.20.1250.20 30 198 2.7E-26 T 06-07-2017 CAL12_RS15015 ed1a6de1f9e897d0057aeca161bcf7ea 345 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 341 1.1E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15015 ed1a6de1f9e897d0057aeca161bcf7ea 345 PIRSF PIRSF017082 12 345 1.8E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15015 ed1a6de1f9e897d0057aeca161bcf7ea 345 SUPERFAMILY SSF53850 130 303 1.15E-11 T 06-07-2017 CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 2.1E-100 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 PIRSF PIRSF005650 1 238 8.8E-92 T 06-07-2017 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 SUPERFAMILY SSF53633 5 237 1.57E-70 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 Gene3D G3DSA:3.40.1160.10 3 237 7.3E-85 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 Pfam PF00696 Amino acid kinase family 7 216 1.5E-28 T 06-07-2017 IPR001048 Aspartate/glutamate/uridylate kinase CAL12_RS12125 43c7533e034aacf36ac067b3e3d90510 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 44.423 T 06-07-2017 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CAL12_RS27810 385ae6007535318dd85033ad6078b9b6 396 Gene3D G3DSA:3.40.50.1970 7 191 1.3E-55 T 06-07-2017 CAL12_RS27810 385ae6007535318dd85033ad6078b9b6 396 Gene3D G3DSA:1.20.1090.10 192 383 7.7E-53 T 06-07-2017 CAL12_RS27810 385ae6007535318dd85033ad6078b9b6 396 SUPERFAMILY SSF56796 5 386 1.83E-122 T 06-07-2017 CAL12_RS27810 385ae6007535318dd85033ad6078b9b6 396 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 180 208 - T 06-07-2017 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CAL12_RS27810 385ae6007535318dd85033ad6078b9b6 396 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 372 3.7E-115 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAL12_RS14580 3124edacd48c11d7907c2021bbce0a12 322 PIRSF PIRSF017082 1 321 6.1E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14580 3124edacd48c11d7907c2021bbce0a12 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 1.0E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14580 3124edacd48c11d7907c2021bbce0a12 322 SUPERFAMILY SSF53850 112 277 1.45E-11 T 06-07-2017 CAL12_RS24700 1768e200aebdd1ead41b0bc56c225760 160 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 83.128 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAL12_RS24700 1768e200aebdd1ead41b0bc56c225760 160 Pfam PF03477 ATP cone domain 50 136 1.5E-14 T 06-07-2017 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CAL12_RS24700 1768e200aebdd1ead41b0bc56c225760 160 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 146 4.0E-60 T 06-07-2017 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CAL12_RS25000 39a8714ad227a824f63630e0241ef02c 276 Gene3D G3DSA:1.10.12.10 218 276 9.9E-19 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS25000 39a8714ad227a824f63630e0241ef02c 276 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS25000 39a8714ad227a824f63630e0241ef02c 276 SUPERFAMILY SSF52096 15 275 7.38E-73 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS25000 39a8714ad227a824f63630e0241ef02c 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 275 1.3E-40 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS25000 39a8714ad227a824f63630e0241ef02c 276 Gene3D G3DSA:3.90.226.10 17 217 3.6E-53 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16690 9cf08a47a2cb02b90b517d6194b8a896 313 SUPERFAMILY SSF103481 203 302 3.53E-15 T 06-07-2017 CAL12_RS16690 9cf08a47a2cb02b90b517d6194b8a896 313 Pfam PF00892 EamA-like transporter family 21 152 2.3E-13 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS16690 9cf08a47a2cb02b90b517d6194b8a896 313 Pfam PF00892 EamA-like transporter family 171 298 8.7E-14 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS16690 9cf08a47a2cb02b90b517d6194b8a896 313 SUPERFAMILY SSF103481 53 153 8.11E-13 T 06-07-2017 CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 Pfam PF00581 Rhodanese-like domain 9 115 2.6E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 Pfam PF00581 Rhodanese-like domain 149 260 3.5E-17 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 Gene3D G3DSA:3.40.250.10 144 268 2.2E-37 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 ProSitePatterns PS00683 Rhodanese C-terminal signature. 248 258 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 SUPERFAMILY SSF52821 142 268 5.63E-35 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 ProSitePatterns PS00380 Rhodanese signature 1. 32 43 - T 06-07-2017 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 Gene3D G3DSA:3.40.250.10 3 117 5.8E-27 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 SMART SM00450 7 122 6.5E-16 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 SMART SM00450 146 264 5.1E-23 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS02485 a02da8274d9f402efa23aaecd121f853 274 SUPERFAMILY SSF52821 2 143 5.63E-26 T 06-07-2017 IPR001763 Rhodanese-like domain CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Gene3D G3DSA:3.50.50.60 141 224 1.3E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Gene3D G3DSA:3.50.50.60 318 375 1.3E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Gene3D G3DSA:3.50.50.60 3 82 1.3E-54 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Pfam PF01266 FAD dependent oxidoreductase 7 357 2.8E-56 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Gene3D G3DSA:3.30.9.10 87 140 9.6E-10 T 06-07-2017 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 Gene3D G3DSA:3.30.9.10 225 316 9.6E-10 T 06-07-2017 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 SUPERFAMILY SSF51905 318 380 5.63E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS15075 acd93008dfad743fec493760b9833ab1 416 SUPERFAMILY SSF51905 6 225 5.63E-51 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS14050 33958854cdb7fff70040e83eef8346de 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 7.4E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14050 33958854cdb7fff70040e83eef8346de 324 PIRSF PIRSF017082 1 323 1.2E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14050 33958854cdb7fff70040e83eef8346de 324 SUPERFAMILY SSF53850 111 285 1.09E-10 T 06-07-2017 CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF14252 Domain of unknown function (DUF4347) 90 249 4.0E-49 T 06-07-2017 IPR025592 Domain of unknown function DUF4347 CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Gene3D G3DSA:2.60.40.10 2136 2229 3.2E-13 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 SUPERFAMILY SSF49313 2137 2228 1.46E-10 T 06-07-2017 IPR015919 Cadherin-like GO:0005509|GO:0016020 CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Gene3D G3DSA:2.60.40.1560 1371 1437 4.7E-4 T 06-07-2017 CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF12245 Bacterial Ig-like domain (group 3) 1527 1542 1.0 T 06-07-2017 IPR022038 Bacterial Ig-like domain CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF12245 Bacterial Ig-like domain (group 3) 714 728 0.1 T 06-07-2017 IPR022038 Bacterial Ig-like domain CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF12245 Bacterial Ig-like domain (group 3) 906 929 2.9 T 06-07-2017 IPR022038 Bacterial Ig-like domain CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF12245 Bacterial Ig-like domain (group 3) 816 834 3.4 T 06-07-2017 IPR022038 Bacterial Ig-like domain CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 Pfam PF12245 Bacterial Ig-like domain (group 3) 1874 1887 0.77 T 06-07-2017 IPR022038 Bacterial Ig-like domain CAL12_RS21455 0f48b4451aab0b569eee6aef7f86de59 2275 SMART SM00736 2133 2233 0.0022 T 06-07-2017 IPR006644 Dystroglycan-type cadherin-like GO:0016020 CAL12_RS10865 1afa0b6e54f9a208d816cdf895a64ce4 267 SUPERFAMILY SSF117396 5 266 1.96E-69 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS10865 1afa0b6e54f9a208d816cdf895a64ce4 267 Pfam PF01904 Protein of unknown function DUF72 23 264 4.1E-57 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS10865 1afa0b6e54f9a208d816cdf895a64ce4 267 Gene3D G3DSA:3.20.20.410 3 266 2.9E-75 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 SUPERFAMILY SSF111369 197 299 2.35E-10 T 06-07-2017 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 Pfam PF13437 HlyD family secretion protein 246 365 9.6E-16 T 06-07-2017 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 Pfam PF13533 Biotin-lipoyl like 79 126 2.7E-17 T 06-07-2017 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 Gene3D G3DSA:2.40.50.100 243 276 2.2E-19 T 06-07-2017 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 Gene3D G3DSA:2.40.50.100 79 112 2.2E-19 T 06-07-2017 CAL12_RS13030 0d265418fdb03c2041fc3faf6a7d55af 410 SUPERFAMILY SSF111369 78 162 2.22E-12 T 06-07-2017 CAL12_RS17400 302ac345b44c06c33995435079efade6 104 Gene3D G3DSA:3.30.1390.10 5 103 1.2E-44 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAL12_RS17400 302ac345b44c06c33995435079efade6 104 SUPERFAMILY SSF54736 19 103 5.75E-33 T 06-07-2017 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CAL12_RS17400 302ac345b44c06c33995435079efade6 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 99 1.3E-36 T 06-07-2017 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CAL12_RS17400 302ac345b44c06c33995435079efade6 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 3 99 29.648 T 06-07-2017 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CAL12_RS20555 34f527147047fb794feb08aa211eeae0 411 SUPERFAMILY SSF111369 79 323 5.89E-63 T 06-07-2017 CAL12_RS20555 34f527147047fb794feb08aa211eeae0 411 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 63 399 2.5E-78 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS20555 34f527147047fb794feb08aa211eeae0 411 Gene3D G3DSA:2.40.50.100 196 220 1.2E-18 T 06-07-2017 CAL12_RS20555 34f527147047fb794feb08aa211eeae0 411 Gene3D G3DSA:2.40.50.100 88 121 1.2E-18 T 06-07-2017 CAL12_RS20555 34f527147047fb794feb08aa211eeae0 411 Pfam PF13533 Biotin-lipoyl like 89 136 1.9E-14 T 06-07-2017 CAL12_RS00560 296a85d1e9d69787a95208aa45e7497f 208 Pfam PF01810 LysE type translocator 16 205 3.5E-37 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS00560 296a85d1e9d69787a95208aa45e7497f 208 PIRSF PIRSF006324 1 208 1.4E-53 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS15850 48a3d6d8ad0c4bf13b83d80eed9521ba 484 Gene3D G3DSA:3.40.309.10 265 442 2.8E-56 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS15850 48a3d6d8ad0c4bf13b83d80eed9521ba 484 SUPERFAMILY SSF53720 5 480 5.11E-144 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS15850 48a3d6d8ad0c4bf13b83d80eed9521ba 484 Pfam PF00171 Aldehyde dehydrogenase family 14 477 6.3E-143 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS15850 48a3d6d8ad0c4bf13b83d80eed9521ba 484 Gene3D G3DSA:3.40.605.10 6 264 7.5E-84 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS25190 07a148acfdb8e06e544c36281cf01329 348 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 10 348 3.1E-170 T 06-07-2017 IPR011960 Gentisate 1,2-dioxygenase CAL12_RS25190 07a148acfdb8e06e544c36281cf01329 348 Pfam PF07883 Cupin domain 94 165 2.1E-22 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS25190 07a148acfdb8e06e544c36281cf01329 348 SUPERFAMILY SSF51182 9 347 3.18E-113 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS25190 07a148acfdb8e06e544c36281cf01329 348 Gene3D G3DSA:2.60.120.10 216 347 3.6E-28 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS25190 07a148acfdb8e06e544c36281cf01329 348 Gene3D G3DSA:2.60.120.10 38 204 1.7E-49 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 Pfam PF09339 IclR helix-turn-helix domain 14 64 1.1E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 SUPERFAMILY SSF46785 13 72 1.77E-9 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 Gene3D G3DSA:3.30.450.40 87 250 4.1E-31 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 Pfam PF01614 Bacterial transcriptional regulator 133 243 3.4E-14 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 SUPERFAMILY SSF55781 83 250 2.81E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 SMART SM00346 11 99 0.008 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS07565 8c5b5bc977f7afba4d974de8a9781cce 253 Gene3D G3DSA:1.10.10.10 10 72 4.1E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 Pfam PF03702 Uncharacterised protein family (UPF0075) 7 372 4.6E-138 T 06-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 6 372 41.065 T 06-07-2017 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 SUPERFAMILY SSF53067 8 42 1.44E-28 T 06-07-2017 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 SUPERFAMILY SSF53067 69 114 1.44E-28 T 06-07-2017 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 SUPERFAMILY SSF53067 144 345 1.44E-28 T 06-07-2017 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 Gene3D G3DSA:3.30.420.40 7 196 1.1E-68 T 06-07-2017 CAL12_RS24725 27360bfd24d9ae1d4b586088bd8d30cc 372 Gene3D G3DSA:3.30.420.40 278 344 1.0E-5 T 06-07-2017 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 Gene3D G3DSA:3.40.50.2300 2 120 5.1E-40 T 06-07-2017 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 SMART SM00448 1 111 2.6E-41 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 Pfam PF00072 Response regulator receiver domain 3 111 2.3E-27 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 Gene3D G3DSA:1.10.10.10 123 220 4.1E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 SMART SM00862 144 219 4.9E-23 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 SUPERFAMILY SSF52172 2 128 6.4E-40 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 1.8E-26 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 218 9.7E-104 T 06-07-2017 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 CAL12_RS00225 38c4272de03bf2473322ca88109eae4e 231 SUPERFAMILY SSF46894 121 219 5.95E-28 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS25545 cf46a63c1ec44fff21087f1426a0c71a 293 SUPERFAMILY SSF53807 19 287 2.12E-57 T 06-07-2017 CAL12_RS25545 cf46a63c1ec44fff21087f1426a0c71a 293 Pfam PF01497 Periplasmic binding protein 45 267 5.9E-20 T 06-07-2017 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CAL12_RS25545 cf46a63c1ec44fff21087f1426a0c71a 293 Gene3D G3DSA:3.40.50.1980 41 158 1.4E-26 T 06-07-2017 CAL12_RS25545 cf46a63c1ec44fff21087f1426a0c71a 293 Gene3D G3DSA:3.40.50.1980 162 289 3.8E-31 T 06-07-2017 CAL12_RS16890 152b3c77b33ff23e190e2159046e74d3 43 SUPERFAMILY SSF51735 6 41 8.29E-6 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS16890 152b3c77b33ff23e190e2159046e74d3 43 Gene3D G3DSA:3.40.50.720 6 42 1.1E-7 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 Pfam PF00034 Cytochrome c 33 112 3.9E-6 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 SUPERFAMILY SSF46626 33 112 3.75E-15 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 PRINTS PR00606 Class ID cytochrome C signature 36 49 6.4E-11 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 PRINTS PR00606 Class ID cytochrome C signature 51 64 6.4E-11 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 PRINTS PR00606 Class ID cytochrome C signature 74 87 6.4E-11 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 PRINTS PR00606 Class ID cytochrome C signature 101 111 6.4E-11 T 06-07-2017 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 CAL12_RS22530 961d5d3f4499534462d68d2ac78bebf0 119 Gene3D G3DSA:1.10.760.10 33 112 1.8E-26 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS09035 11d0c4d22fd994e1c0f9f1775cf94000 137 SUPERFAMILY SSF110857 3 120 1.07E-23 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS09035 11d0c4d22fd994e1c0f9f1775cf94000 137 Gene3D G3DSA:3.10.490.10 3 131 1.4E-24 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS09035 11d0c4d22fd994e1c0f9f1775cf94000 137 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 128 7.9E-18 T 06-07-2017 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CAL12_RS20530 7e96d64ba9e9584c55faec2e69ccb6ce 173 Gene3D G3DSA:2.160.10.10 2 164 5.2E-45 T 06-07-2017 CAL12_RS20530 7e96d64ba9e9584c55faec2e69ccb6ce 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 9.4E-10 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS20530 7e96d64ba9e9584c55faec2e69ccb6ce 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 15 44 7.6E-6 T 06-07-2017 IPR001451 Hexapeptide repeat CAL12_RS20530 7e96d64ba9e9584c55faec2e69ccb6ce 173 SUPERFAMILY SSF51161 3 158 2.22E-43 T 06-07-2017 IPR011004 Trimeric LpxA-like CAL12_RS12825 aa1a5798059ffa8f68e831247b5341a2 285 SUPERFAMILY SSF53474 11 279 1.04E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12825 aa1a5798059ffa8f68e831247b5341a2 285 Gene3D G3DSA:3.40.50.1820 11 280 2.6E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS12825 aa1a5798059ffa8f68e831247b5341a2 285 Pfam PF00561 alpha/beta hydrolase fold 44 267 2.4E-21 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 SUPERFAMILY SSF52402 7 209 6.52E-63 T 06-07-2017 CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 Gene3D G3DSA:3.40.50.620 243 251 2.0E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 Gene3D G3DSA:3.40.50.620 7 210 2.0E-50 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 10 302 2.8E-125 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 255 1.0E-45 T 06-07-2017 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CAL12_RS18735 5ba3ee54369ef85414b47ca55bd1bc30 302 PIRSF PIRSF002936 1 302 1.3E-138 T 06-07-2017 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CAL12_RS03800 5f3ef97d9ddaf0259eaeee2b656605ac 387 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 30 348 3.7E-131 T 06-07-2017 IPR017778 ABC transporter, urea, permease protein, UrtC CAL12_RS03800 5f3ef97d9ddaf0259eaeee2b656605ac 387 Pfam PF02653 Branched-chain amino acid transport system / permease component 38 338 5.1E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS03135 5a24b8ef3f5974b6851005aaec0e3c51 330 PIRSF PIRSF017082 2 330 5.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03135 5a24b8ef3f5974b6851005aaec0e3c51 330 SUPERFAMILY SSF53850 119 299 5.43E-13 T 06-07-2017 CAL12_RS03135 5a24b8ef3f5974b6851005aaec0e3c51 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 326 2.2E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02730 4ed84fb1fbb141e1ea21a6d17b2551c2 249 SUPERFAMILY SSF48317 18 230 3.27E-16 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS02730 4ed84fb1fbb141e1ea21a6d17b2551c2 249 Pfam PF01569 PAP2 superfamily 110 230 4.8E-12 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS02730 4ed84fb1fbb141e1ea21a6d17b2551c2 249 Gene3D G3DSA:1.20.144.10 42 230 1.2E-7 T 06-07-2017 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CAL12_RS26950 e4320cfeea56164aa6bc15adf5ff8ad6 335 SUPERFAMILY SSF53448 2 219 1.1E-25 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26950 e4320cfeea56164aa6bc15adf5ff8ad6 335 Gene3D G3DSA:3.90.550.10 3 173 6.6E-19 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS26950 e4320cfeea56164aa6bc15adf5ff8ad6 335 Pfam PF00535 Glycosyl transferase family 2 3 140 6.8E-19 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS19765 1445dee8ae9ac7b0d46a0269ac29dc8d 129 SMART SM00448 10 121 2.2E-21 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS19765 1445dee8ae9ac7b0d46a0269ac29dc8d 129 SUPERFAMILY SSF52172 8 126 6.12E-30 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS19765 1445dee8ae9ac7b0d46a0269ac29dc8d 129 Gene3D G3DSA:3.40.50.2300 8 126 8.4E-28 T 06-07-2017 CAL12_RS19765 1445dee8ae9ac7b0d46a0269ac29dc8d 129 Pfam PF00072 Response regulator receiver domain 12 121 3.2E-17 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 SUPERFAMILY SSF51735 7 263 1.26E-69 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 262 5.1E-57 T 06-07-2017 CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 5.2E-32 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 1.1E-9 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS07430 23735d41b06e013e80e35011e5549c89 266 Gene3D G3DSA:3.40.50.720 2 263 2.1E-73 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS00895 e1d2a7d488e3b88225fd360a708ef21a 176 Pfam PF02417 Chromate transporter 8 170 7.1E-37 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 195 271 1.1E-23 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 197 271 2.0E-23 T 06-07-2017 IPR006260 TonB, C-terminal GO:0006810 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 Gene3D G3DSA:3.30.1150.10 153 272 4.1E-20 T 06-07-2017 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 SUPERFAMILY SSF74653 194 269 6.28E-22 T 06-07-2017 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 PRINTS PR01374 Gram-negative bacterial tonB protein signature 125 135 1.4E-6 T 06-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 PRINTS PR01374 Gram-negative bacterial tonB protein signature 210 228 1.4E-6 T 06-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CAL12_RS17560 1cdaf8d257b5908623e19f284c64f36e 273 PRINTS PR01374 Gram-negative bacterial tonB protein signature 189 210 1.4E-6 T 06-07-2017 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 CAL12_RS04665 736377bbb3fb69e9d2dd48130eafdf65 208 Pfam PF13360 PQQ-like domain 72 169 3.9E-4 T 06-07-2017 IPR002372 Pyrrolo-quinoline quinone repeat CAL12_RS04665 736377bbb3fb69e9d2dd48130eafdf65 208 Gene3D G3DSA:2.130.10.10 15 205 2.3E-17 T 06-07-2017 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CAL12_RS04665 736377bbb3fb69e9d2dd48130eafdf65 208 SUPERFAMILY SSF50969 15 206 4.39E-24 T 06-07-2017 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CAL12_RS25195 7397a681c10749d75ce49cca460dcaec 232 Gene3D G3DSA:3.90.850.10 22 232 4.0E-78 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS25195 7397a681c10749d75ce49cca460dcaec 232 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 232 1.1E-51 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS25195 7397a681c10749d75ce49cca460dcaec 232 SUPERFAMILY SSF56529 22 232 6.67E-68 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS09905 3640fdccffd61ebcab5ac9a4f051d016 356 Pfam PF02615 Malate/L-lactate dehydrogenase 15 343 6.1E-117 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS09905 3640fdccffd61ebcab5ac9a4f051d016 356 Gene3D G3DSA:3.30.1370.60 85 283 2.3E-77 T 06-07-2017 CAL12_RS09905 3640fdccffd61ebcab5ac9a4f051d016 356 SUPERFAMILY SSF89733 12 353 3.53E-104 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS09905 3640fdccffd61ebcab5ac9a4f051d016 356 Gene3D G3DSA:1.10.1530.10 13 84 6.4E-19 T 06-07-2017 CAL12_RS06315 fceb185658833339fa0519820856345f 409 PIRSF PIRSF036542 1 409 1.2E-201 T 06-07-2017 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB CAL12_RS06315 fceb185658833339fa0519820856345f 409 Pfam PF07670 Nucleoside recognition 277 379 7.7E-6 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CAL12_RS06315 fceb185658833339fa0519820856345f 409 Pfam PF07670 Nucleoside recognition 52 157 1.2E-8 T 06-07-2017 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CAL12_RS14675 76e640e653dfcbcd024a65dd279fcc69 322 Pfam PF12697 Alpha/beta hydrolase family 34 292 3.9E-11 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS14675 76e640e653dfcbcd024a65dd279fcc69 322 SUPERFAMILY SSF53474 4 145 3.63E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14675 76e640e653dfcbcd024a65dd279fcc69 322 SUPERFAMILY SSF53474 230 313 3.63E-51 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14675 76e640e653dfcbcd024a65dd279fcc69 322 Gene3D G3DSA:3.40.50.1820 3 140 3.0E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS14675 76e640e653dfcbcd024a65dd279fcc69 322 Gene3D G3DSA:3.40.50.1820 237 311 3.0E-55 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS27145 b4a32a03bcb2d1998226fa3e76e5d946 103 SUPERFAMILY SSF54292 21 97 1.84E-17 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS27145 b4a32a03bcb2d1998226fa3e76e5d946 103 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 19 98 7.0E-23 T 06-07-2017 CAL12_RS27145 b4a32a03bcb2d1998226fa3e76e5d946 103 Gene3D G3DSA:3.10.20.30 30 89 1.1E-4 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS04130 8e8ced7d6917b61808ae6cef36524be5 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 280 5.1E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04130 8e8ced7d6917b61808ae6cef36524be5 286 SUPERFAMILY SSF161098 87 270 2.09E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS04130 8e8ced7d6917b61808ae6cef36524be5 286 Gene3D G3DSA:1.10.3720.10 87 280 1.0E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS26610 084a5d794bb9a8493edcfa422122d255 282 SUPERFAMILY SSF51730 4 278 1.57E-94 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAL12_RS26610 084a5d794bb9a8493edcfa422122d255 282 Pfam PF02219 Methylenetetrahydrofolate reductase 4 278 1.5E-90 T 06-07-2017 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CAL12_RS26610 084a5d794bb9a8493edcfa422122d255 282 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 9 278 1.6E-95 T 06-07-2017 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CAL12_RS26610 084a5d794bb9a8493edcfa422122d255 282 Gene3D G3DSA:3.20.20.220 4 279 6.8E-101 T 06-07-2017 IPR029041 FAD-linked oxidoreductase-like CAL12_RS19880 02cf58ddeccfa6d6eab56410156d3962 213 Pfam PF06532 Protein of unknown function (DUF1109) 10 213 1.7E-43 T 06-07-2017 IPR009495 Protein of unknown function DUF1109 CAL12_RS10380 8a889709fd7f47a357bdf12f1ee27a62 267 SUPERFAMILY SSF53474 7 265 4.15E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS10380 8a889709fd7f47a357bdf12f1ee27a62 267 Pfam PF12697 Alpha/beta hydrolase family 29 254 4.2E-17 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS10380 8a889709fd7f47a357bdf12f1ee27a62 267 Gene3D G3DSA:3.40.50.1820 6 264 9.1E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS00645 ef5f87b405f847a66a679618d8c5d7a7 265 SUPERFAMILY SSF161098 6 263 6.28E-60 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00645 ef5f87b405f847a66a679618d8c5d7a7 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 257 2.3E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00645 ef5f87b405f847a66a679618d8c5d7a7 265 Gene3D G3DSA:1.10.3720.10 7 253 1.6E-55 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 SUPERFAMILY SSF53474 1 265 6.22E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 Pfam PF00561 alpha/beta hydrolase fold 20 247 4.2E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 Gene3D G3DSA:3.40.50.1820 2 266 1.0E-57 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS23505 63d5069b79a2c63ebd018186f1110a58 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 1.5E-9 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS13245 bf6fd430ff8d71bfaa53221425a65d61 319 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 187 204 - T 06-07-2017 IPR000540 Flagellar motor protein MotA, conserved site CAL12_RS13245 bf6fd430ff8d71bfaa53221425a65d61 319 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 221 3.7E-20 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAL12_RS14920 9859502d887a4477ddc900bcd4fd5b74 182 Pfam PF11821 Protein of unknown function (DUF3341) 6 159 1.4E-55 T 06-07-2017 IPR021776 Protein of unknown function DUF3341 CAL12_RS24950 6e2fb2edef9fd4b3c1453edcd2c0eea0 243 Gene3D G3DSA:3.40.1130.10 62 177 3.5E-12 T 06-07-2017 CAL12_RS24950 6e2fb2edef9fd4b3c1453edcd2c0eea0 243 SMART SM00563 67 179 2.4E-30 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS24950 6e2fb2edef9fd4b3c1453edcd2c0eea0 243 Pfam PF01553 Acyltransferase 55 176 1.4E-20 T 06-07-2017 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CAL12_RS24950 6e2fb2edef9fd4b3c1453edcd2c0eea0 243 SUPERFAMILY SSF69593 15 241 1.83E-27 T 06-07-2017 CAL12_RS24215 e1310a0db5060a749e67dd004fc372db 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 2.1E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24215 e1310a0db5060a749e67dd004fc372db 324 PIRSF PIRSF017082 1 324 6.1E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24215 e1310a0db5060a749e67dd004fc372db 324 SUPERFAMILY SSF53850 113 280 6.79E-8 T 06-07-2017 CAL12_RS21750 9cefef3308faa7a300f3bf0dc167742b 435 Pfam PF00285 Citrate synthase, C-terminal domain 94 428 4.6E-52 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS21750 9cefef3308faa7a300f3bf0dc167742b 435 Gene3D G3DSA:1.10.580.10 97 311 1.5E-26 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS21750 9cefef3308faa7a300f3bf0dc167742b 435 Gene3D G3DSA:1.10.230.10 312 389 6.2E-10 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS21750 9cefef3308faa7a300f3bf0dc167742b 435 SUPERFAMILY SSF48256 93 434 9.03E-60 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS24145 6c6da1d3edf5f9894ddbfef958f480a6 223 SUPERFAMILY SSF161098 19 213 1.83E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24145 6c6da1d3edf5f9894ddbfef958f480a6 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 220 1.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24145 6c6da1d3edf5f9894ddbfef958f480a6 223 Gene3D G3DSA:1.10.3720.10 17 220 4.7E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24145 6c6da1d3edf5f9894ddbfef958f480a6 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 113 4.2E-17 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS18490 ef3f9417b0a8bf3c16f58ae25266ad50 280 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 277 1.4E-72 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS18490 ef3f9417b0a8bf3c16f58ae25266ad50 280 SUPERFAMILY SSF56529 61 278 9.94E-82 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS18490 ef3f9417b0a8bf3c16f58ae25266ad50 280 Gene3D G3DSA:3.90.850.10 68 278 6.5E-88 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 Pfam PF03466 LysR substrate binding domain 88 292 4.2E-43 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 Gene3D G3DSA:3.40.190.10 177 261 2.5E-23 T 06-07-2017 CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 Gene3D G3DSA:3.40.190.10 92 176 4.0E-25 T 06-07-2017 CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 SUPERFAMILY SSF46785 3 112 1.03E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 SUPERFAMILY SSF53850 89 296 1.55E-44 T 06-07-2017 CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 Gene3D G3DSA:1.10.10.10 4 83 8.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS26650 f7fcd5f62e7d5663dddf716ce77ee0a4 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 5.6E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS15590 f87f79a45e8f1cf61916fb9709bfbaed 106 SUPERFAMILY SSF48452 10 92 4.51E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS15590 f87f79a45e8f1cf61916fb9709bfbaed 106 Gene3D G3DSA:1.25.40.10 12 92 4.5E-13 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS15590 f87f79a45e8f1cf61916fb9709bfbaed 106 Pfam PF13432 Tetratricopeptide repeat 25 86 1.4E-6 T 06-07-2017 CAL12_RS09510 faea185caee92884d8a1453beeb5c7be 241 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 185 3.0E-68 T 06-07-2017 IPR022301 Integral membrane protein YjbE CAL12_RS09510 faea185caee92884d8a1453beeb5c7be 241 Pfam PF03741 Integral membrane protein TerC family 14 183 1.0E-44 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 Pfam PF12697 Alpha/beta hydrolase family 42 277 7.4E-22 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 Gene3D G3DSA:3.40.50.1820 21 285 2.5E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 229 243 4.3E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 4.3E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 80 4.3E-6 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 SUPERFAMILY SSF53474 19 283 8.98E-50 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00412 Epoxide hydrolase signature 65 80 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00412 Epoxide hydrolase signature 227 243 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS19810 3a1de37bafecadebaf93b9184f475493 286 PRINTS PR00412 Epoxide hydrolase signature 260 282 3.2E-6 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS00245 846fba9299fed7cc4e43ecf2ecb86e5b 163 Pfam PF13663 Domain of unknown function (DUF4148) 57 125 2.2E-10 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS01580 f6879b9e35fd76523c5709aaab96b1ea 328 SUPERFAMILY SSF53850 114 291 1.78E-13 T 06-07-2017 CAL12_RS01580 f6879b9e35fd76523c5709aaab96b1ea 328 PIRSF PIRSF017082 1 327 9.5E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01580 f6879b9e35fd76523c5709aaab96b1ea 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 324 4.3E-93 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 PRINTS PR00412 Epoxide hydrolase signature 259 281 3.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 PRINTS PR00412 Epoxide hydrolase signature 113 126 3.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 PRINTS PR00412 Epoxide hydrolase signature 33 51 3.6E-7 T 06-07-2017 IPR000639 Epoxide hydrolase-like GO:0003824 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 Gene3D G3DSA:3.40.50.1820 2 284 4.1E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 SUPERFAMILY SSF53474 3 284 7.08E-67 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 7.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 7.8E-7 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS25230 b915b72dade7773105c8962fc4c8e187 286 Pfam PF00561 alpha/beta hydrolase fold 29 270 6.4E-33 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 Pfam PF00561 alpha/beta hydrolase fold 43 281 8.9E-20 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 68 83 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 PRINTS PR00111 Alpha/beta hydrolase fold signature 238 252 1.5E-5 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 Gene3D G3DSA:3.40.50.1820 9 291 3.1E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS16870 7d0ce62f3c527a3fdb0426286758ecd7 301 SUPERFAMILY SSF53474 19 291 4.18E-60 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19600 b2c33ef705e687057bef0f5bee90bc41 172 Pfam PF02627 Carboxymuconolactone decarboxylase family 95 165 9.8E-11 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS19600 b2c33ef705e687057bef0f5bee90bc41 172 Gene3D G3DSA:1.20.1290.10 3 167 4.6E-43 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS19600 b2c33ef705e687057bef0f5bee90bc41 172 SUPERFAMILY SSF69118 3 169 2.07E-39 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS19600 b2c33ef705e687057bef0f5bee90bc41 172 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 172 70.661 T 06-07-2017 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS19600 b2c33ef705e687057bef0f5bee90bc41 172 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 109 157 1.5E-9 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS21995 2e7d56a2b3c2d7e0d0e8297a84493849 763 Pfam PF05170 AsmA family 1 639 3.4E-116 T 06-07-2017 IPR007844 AsmA CAL12_RS20615 dd1b03c52d5191b31eec522ea809281d 295 Pfam PF08007 Cupin superfamily protein 11 270 1.3E-35 T 06-07-2017 IPR003347 JmjC domain CAL12_RS20615 dd1b03c52d5191b31eec522ea809281d 295 SUPERFAMILY SSF51197 8 283 3.3E-38 T 06-07-2017 CAL12_RS20615 dd1b03c52d5191b31eec522ea809281d 295 SMART SM00558 96 233 4.9E-4 T 06-07-2017 IPR003347 JmjC domain CAL12_RS20615 dd1b03c52d5191b31eec522ea809281d 295 Gene3D G3DSA:2.60.120.650 8 218 1.3E-25 T 06-07-2017 CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 9.0E-14 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 Gene3D G3DSA:3.40.190.10 95 181 8.9E-23 T 06-07-2017 CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 SUPERFAMILY SSF46785 4 115 2.68E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 SUPERFAMILY SSF53850 92 295 1.99E-39 T 06-07-2017 CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 Gene3D G3DSA:3.40.190.10 182 262 8.2E-6 T 06-07-2017 CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 Pfam PF03466 LysR substrate binding domain 92 295 1.8E-38 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS16310 b308cd6cc50f3120b4fa2d200e10fd3b 303 Gene3D G3DSA:1.10.10.10 5 89 7.8E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06000 838816b3c0ddfb4620188f5fe2743caf 396 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 48 362 2.5E-136 T 06-07-2017 IPR017778 ABC transporter, urea, permease protein, UrtC CAL12_RS06000 838816b3c0ddfb4620188f5fe2743caf 396 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 351 1.4E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 Gene3D G3DSA:1.20.1600.10 54 465 2.6E-111 T 06-07-2017 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 SUPERFAMILY SSF56954 3 23 6.28E-109 T 06-07-2017 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 SUPERFAMILY SSF56954 55 465 6.28E-109 T 06-07-2017 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 Pfam PF02321 Outer membrane efflux protein 277 459 1.7E-25 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 Pfam PF02321 Outer membrane efflux protein 64 252 7.1E-30 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS25090 246c2f20cefe80104758959ae8868455 510 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 461 9.5E-127 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 Gene3D G3DSA:1.10.10.10 6 79 1.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 Pfam PF03466 LysR substrate binding domain 88 296 1.7E-44 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.1E-5 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 Gene3D G3DSA:3.40.190.10 88 165 3.6E-8 T 06-07-2017 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.1E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 SUPERFAMILY SSF46785 6 112 9.54E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 SUPERFAMILY SSF53850 90 299 5.79E-45 T 06-07-2017 CAL12_RS05855 81baea0d887394b887be447ad0c5b2b7 311 Gene3D G3DSA:3.40.190.10 166 260 3.4E-23 T 06-07-2017 CAL12_RS05690 2435dda0ae0d8727b36ded3686aaa5d4 140 Pfam PF13474 SnoaL-like domain 10 124 4.9E-17 T 06-07-2017 IPR009959 Polyketide cyclase SnoaL-like domain CAL12_RS05690 2435dda0ae0d8727b36ded3686aaa5d4 140 Gene3D G3DSA:3.10.450.50 2 128 9.0E-37 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS05690 2435dda0ae0d8727b36ded3686aaa5d4 140 SUPERFAMILY SSF54427 2 122 1.23E-29 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS23380 7e1e65a1cd99176a423ac069dddff233 324 PIRSF PIRSF017082 1 323 2.1E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23380 7e1e65a1cd99176a423ac069dddff233 324 SUPERFAMILY SSF53850 90 285 6.3E-9 T 06-07-2017 CAL12_RS23380 7e1e65a1cd99176a423ac069dddff233 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 320 1.7E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20395 df82e6eb4fcc112ace265b19f64573b2 196 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 3 109 9.4E-6 T 06-07-2017 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain CAL12_RS20395 df82e6eb4fcc112ace265b19f64573b2 196 Gene3D G3DSA:1.10.287.130 145 189 5.2E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS20395 df82e6eb4fcc112ace265b19f64573b2 196 SUPERFAMILY SSF47384 145 184 1.02E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 58 458 5.0E-57 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 36 473 3.3E-83 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 Gene3D G3DSA:3.40.710.10 46 95 2.9E-4 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 300 322 2.1E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 435 448 2.1E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 373 387 2.1E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 358 372 2.1E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 70 89 2.1E-25 T 06-07-2017 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 Gene3D G3DSA:3.40.710.10 244 477 8.2E-69 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS04940 4166d057d356afae6ae4a6bd2e31833a 478 SUPERFAMILY SSF56601 31 477 8.88E-88 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS00595 dc128e11e3613d917d81e0c77a24b1d2 427 SUPERFAMILY SSF75304 5 421 5.1E-115 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS00595 dc128e11e3613d917d81e0c77a24b1d2 427 Pfam PF01425 Amidase 25 413 2.6E-80 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS00595 dc128e11e3613d917d81e0c77a24b1d2 427 Gene3D G3DSA:3.90.1300.10 4 423 3.6E-116 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS20095 316445a3bbe6ae4fc483f9385ae5dbca 335 Gene3D G3DSA:1.10.3720.10 91 162 1.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20095 316445a3bbe6ae4fc483f9385ae5dbca 335 Gene3D G3DSA:1.10.3720.10 200 330 1.3E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20095 316445a3bbe6ae4fc483f9385ae5dbca 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 334 2.3E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20095 316445a3bbe6ae4fc483f9385ae5dbca 335 SUPERFAMILY SSF161098 197 317 1.16E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20095 316445a3bbe6ae4fc483f9385ae5dbca 335 SUPERFAMILY SSF161098 92 159 1.16E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS20015 a8974c469cefe378dd1f1095ea648dd1 323 PIRSF PIRSF017082 1 323 2.1E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20015 a8974c469cefe378dd1f1095ea648dd1 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 2.8E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20015 a8974c469cefe378dd1f1095ea648dd1 323 SUPERFAMILY SSF53850 114 284 1.38E-13 T 06-07-2017 CAL12_RS18105 7faffb218b547382f6d1ae23734ba258 339 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 333 5.0E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS18105 7faffb218b547382f6d1ae23734ba258 339 SUPERFAMILY SSF53850 127 302 5.43E-17 T 06-07-2017 CAL12_RS18105 7faffb218b547382f6d1ae23734ba258 339 Gene3D G3DSA:3.40.190.10 143 242 1.0E-4 T 06-07-2017 CAL12_RS18105 7faffb218b547382f6d1ae23734ba258 339 PIRSF PIRSF017082 11 338 6.2E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25460 e3dd7a77b5b8010bf27a98d1a7bcbd0f 637 Pfam PF01964 Radical SAM ThiC family 138 598 5.1E-198 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAL12_RS25460 e3dd7a77b5b8010bf27a98d1a7bcbd0f 637 Pfam PF13667 ThiC-associated domain 21 98 4.3E-33 T 06-07-2017 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAL12_RS25460 e3dd7a77b5b8010bf27a98d1a7bcbd0f 637 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 137 604 56.144 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAL12_RS25460 e3dd7a77b5b8010bf27a98d1a7bcbd0f 637 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 137 602 3.9E-213 T 06-07-2017 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CAL12_RS10290 805a9e6ebb3011970f10de9aab0faf21 347 Gene3D G3DSA:3.60.15.10 55 340 2.7E-57 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS10290 805a9e6ebb3011970f10de9aab0faf21 347 SMART SM00849 111 317 1.1E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS10290 805a9e6ebb3011970f10de9aab0faf21 347 SUPERFAMILY SSF56281 53 339 1.02E-52 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS10290 805a9e6ebb3011970f10de9aab0faf21 347 Pfam PF00753 Metallo-beta-lactamase superfamily 110 303 3.5E-14 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS03085 6ce3aff8db6c3d4ec7f8f56a8ce3ba92 383 Pfam PF04632 Fusaric acid resistance protein family 47 342 5.9E-16 T 06-07-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 SUPERFAMILY SSF53850 241 689 4.52E-89 T 06-07-2017 CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 SUPERFAMILY SSF53850 35 132 4.52E-89 T 06-07-2017 CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 SUPERFAMILY SSF53850 167 201 4.52E-89 T 06-07-2017 CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 Gene3D G3DSA:3.10.105.10 418 658 9.1E-48 T 06-07-2017 CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 170 604 3.6E-52 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS08100 cf0abd56a2b1426c68a81935cba8ae02 745 Gene3D G3DSA:3.90.76.10 50 307 2.3E-26 T 06-07-2017 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 Gene3D G3DSA:3.40.309.10 271 449 6.7E-74 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 284 295 - T 06-07-2017 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 Pfam PF00171 Aldehyde dehydrogenase family 19 484 3.1E-182 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 Gene3D G3DSA:3.40.605.10 9 270 8.8E-101 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 06-07-2017 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CAL12_RS10550 5c5fb123940101bbebde3e6fef6df8d2 499 SUPERFAMILY SSF53720 9 487 5.24E-178 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS11370 e895b64a3a9f7801fa3ab9d4fa67c5e7 137 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 38 137 9.4E-34 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS18340 2ca159cb1735db450e343a0a986af2d8 292 Pfam PF01435 Peptidase family M48 81 289 9.6E-39 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAL12_RS18340 2ca159cb1735db450e343a0a986af2d8 292 Hamap MF_00188 Protease HtpX [htpX]. 1 290 24.748 T 06-07-2017 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CAL12_RS18340 2ca159cb1735db450e343a0a986af2d8 292 Gene3D G3DSA:3.30.2010.10 76 163 8.6E-29 T 06-07-2017 CAL12_RS17050 a10cb46f52755f5a0427f8c6e5d99919 286 Pfam PF13679 Methyltransferase domain 34 175 1.6E-45 T 06-07-2017 IPR025714 Methyltransferase domain CAL12_RS17050 a10cb46f52755f5a0427f8c6e5d99919 286 SUPERFAMILY SSF53335 41 173 5.01E-15 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17050 a10cb46f52755f5a0427f8c6e5d99919 286 Gene3D G3DSA:3.40.50.150 61 174 9.0E-7 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS21865 1927a0dbb043f41b25b594fa7cc7099f 367 PIRSF PIRSF017082 36 366 2.6E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21865 1927a0dbb043f41b25b594fa7cc7099f 367 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 91 364 2.7E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21865 1927a0dbb043f41b25b594fa7cc7099f 367 SUPERFAMILY SSF53850 157 336 2.71E-12 T 06-07-2017 CAL12_RS11485 a20a4060344daaf95c92b9ff0488be57 88 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 7 77 3.9E-11 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS05615 ba11da1e0e3d0746947bb0f73db1e1d5 137 SUPERFAMILY SSF55298 5 134 1.43E-29 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS05615 ba11da1e0e3d0746947bb0f73db1e1d5 137 Pfam PF01042 Endoribonuclease L-PSP 26 131 1.9E-17 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS05615 ba11da1e0e3d0746947bb0f73db1e1d5 137 Gene3D G3DSA:3.30.1330.40 6 134 6.6E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS25140 959eb9cdedea4ee5db03d4e735191093 296 Pfam PF02616 Segregation and condensation protein ScpA 71 286 2.9E-32 T 06-07-2017 IPR003768 Segregation and condensation protein A CAL12_RS25140 959eb9cdedea4ee5db03d4e735191093 296 Hamap MF_01805 Segregation and condensation protein A [scpA]. 54 288 20.497 T 06-07-2017 IPR003768 Segregation and condensation protein A CAL12_RS13550 f59f7b2151277ca23357eec3fac05374 325 SUPERFAMILY SSF53850 115 284 5.76E-11 T 06-07-2017 CAL12_RS13550 f59f7b2151277ca23357eec3fac05374 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 2.0E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13550 f59f7b2151277ca23357eec3fac05374 325 PIRSF PIRSF017082 1 324 1.6E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS09970 d7808ab58ae952da1a7e76389a524e27 120 SMART SM00448 2 113 1.9E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS09970 d7808ab58ae952da1a7e76389a524e27 120 SUPERFAMILY SSF52172 3 118 2.56E-28 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS09970 d7808ab58ae952da1a7e76389a524e27 120 Gene3D G3DSA:3.40.50.2300 2 119 8.7E-29 T 06-07-2017 CAL12_RS09970 d7808ab58ae952da1a7e76389a524e27 120 Pfam PF00072 Response regulator receiver domain 4 112 5.2E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14495 f1d2c516e73067089742823d1ca30492 223 Gene3D G3DSA:3.60.20.10 1 213 5.0E-70 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS14495 f1d2c516e73067089742823d1ca30492 223 Pfam PF06267 Family of unknown function (DUF1028) 2 190 3.1E-62 T 06-07-2017 IPR010430 Protein of unknown function DUF1028 CAL12_RS14495 f1d2c516e73067089742823d1ca30492 223 SUPERFAMILY SSF56235 1 222 3.4E-70 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS20465 7f6ded9d26c5d5846a050f1a384218f9 263 Gene3D G3DSA:3.40.50.880 1 260 6.0E-62 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS20465 7f6ded9d26c5d5846a050f1a384218f9 263 Pfam PF01965 DJ-1/PfpI family 33 157 1.0E-7 T 06-07-2017 IPR002818 DJ-1/PfpI CAL12_RS20465 7f6ded9d26c5d5846a050f1a384218f9 263 SUPERFAMILY SSF52317 5 259 1.58E-42 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS26415 38873f4261cd2d147b8a5dd2e671a168 444 Gene3D G3DSA:3.40.50.2300 39 237 1.1E-16 T 06-07-2017 CAL12_RS26415 38873f4261cd2d147b8a5dd2e671a168 444 SUPERFAMILY SSF53822 34 408 1.35E-46 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS26415 38873f4261cd2d147b8a5dd2e671a168 444 Pfam PF13458 Periplasmic binding protein 33 402 1.9E-75 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS13840 e72a08131e68a8a10b69e485a18bc04c 110 TIGRFAM TIGR02953 penta_MxKDx: pentapeptide MXKDX repeat protein 3 81 6.8E-15 T 06-07-2017 IPR014299 Pentapeptide MXKDX repeat protein CAL12_RS01385 a9609592ca98d506a4ef59f3916301cb 354 Gene3D G3DSA:3.40.190.10 154 294 3.5E-29 T 06-07-2017 CAL12_RS01385 a9609592ca98d506a4ef59f3916301cb 354 SUPERFAMILY SSF53850 35 347 2.17E-58 T 06-07-2017 CAL12_RS01385 a9609592ca98d506a4ef59f3916301cb 354 Gene3D G3DSA:3.40.190.10 38 153 6.4E-5 T 06-07-2017 CAL12_RS01385 a9609592ca98d506a4ef59f3916301cb 354 Pfam PF13416 Bacterial extracellular solute-binding protein 57 315 1.9E-29 T 06-07-2017 CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 SMART SM00346 10 104 5.2E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 Gene3D G3DSA:1.10.10.10 8 83 1.5E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 SUPERFAMILY SSF55781 72 238 6.34E-45 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 SUPERFAMILY SSF46785 13 88 5.53E-12 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 Pfam PF09339 IclR helix-turn-helix domain 15 59 5.4E-10 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 Gene3D G3DSA:3.30.450.40 87 235 1.7E-50 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS05440 081e30411fe7026d1a01202e38aabe15 279 Pfam PF01614 Bacterial transcriptional regulator 132 231 1.8E-28 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS14370 49e0563991e6eda032bc3549a8c01f7e 137 Gene3D G3DSA:3.40.50.2300 7 126 4.2E-33 T 06-07-2017 CAL12_RS14370 49e0563991e6eda032bc3549a8c01f7e 137 SUPERFAMILY SSF52172 7 127 3.13E-29 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS14370 49e0563991e6eda032bc3549a8c01f7e 137 Pfam PF00072 Response regulator receiver domain 8 121 7.2E-19 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS14370 49e0563991e6eda032bc3549a8c01f7e 137 SMART SM00448 6 124 4.0E-22 T 06-07-2017 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CAL12_RS16780 28d3270bf36c61228bf9e837c73cbdc7 146 Gene3D G3DSA:3.10.450.50 16 122 6.2E-5 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS16780 28d3270bf36c61228bf9e837c73cbdc7 146 SUPERFAMILY SSF54427 14 138 9.72E-12 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 Pfam PF00005 ABC transporter 406 566 1.2E-26 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 SUPERFAMILY SSF52540 389 636 2.66E-59 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 341 2.7E-38 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 Gene3D G3DSA:3.40.50.300 388 634 1.0E-63 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 615 637 1.4E-7 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS26455 19a74510c03482154d0bd61782f6cff8 642 SMART SM00382 415 614 2.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 Pfam PF03466 LysR substrate binding domain 88 294 2.5E-37 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.7E-19 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 Gene3D G3DSA:3.40.190.10 180 262 1.9E-16 T 06-07-2017 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 Gene3D G3DSA:3.40.190.10 93 179 1.4E-12 T 06-07-2017 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.0E-8 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 SUPERFAMILY SSF53850 90 295 1.63E-36 T 06-07-2017 CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 SUPERFAMILY SSF46785 1 112 7.1E-23 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09485 2cfe9cac85b4459e3327d90ca2effb83 320 Gene3D G3DSA:1.10.10.10 1 87 7.1E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS03955 e21302475fb3d470153be014f1cc12b2 133 Pfam PF14552 Tautomerase enzyme 39 120 2.9E-20 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS03955 e21302475fb3d470153be014f1cc12b2 133 SUPERFAMILY SSF55331 2 128 1.02E-30 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS03955 e21302475fb3d470153be014f1cc12b2 133 Gene3D G3DSA:3.30.429.10 13 129 7.9E-27 T 06-07-2017 CAL12_RS05925 3cec5f003e22c2d775b0513c4121f9a6 328 Gene3D G3DSA:3.40.190.10 132 231 4.4E-6 T 06-07-2017 CAL12_RS05925 3cec5f003e22c2d775b0513c4121f9a6 328 SUPERFAMILY SSF53850 116 286 2.56E-17 T 06-07-2017 CAL12_RS05925 3cec5f003e22c2d775b0513c4121f9a6 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 1.8E-87 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05925 3cec5f003e22c2d775b0513c4121f9a6 328 PIRSF PIRSF017082 2 327 5.7E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10520 1c6073dfec624ff2db75030fb606d478 120 Pfam PF04234 CopC domain 22 118 1.4E-20 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CAL12_RS10520 1c6073dfec624ff2db75030fb606d478 120 Gene3D G3DSA:2.60.40.1220 21 119 4.6E-25 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like CAL12_RS10520 1c6073dfec624ff2db75030fb606d478 120 SUPERFAMILY SSF81296 21 118 5.11E-24 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS19860 8bbdf78accbe770c12eeca35db7a7bc3 103 Pfam PF10048 Predicted integral membrane protein (DUF2282) 42 93 6.2E-23 T 06-07-2017 IPR018740 Protein of unknown function DUF2282, integral membrane CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 7.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 7.4E-5 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 2.7E-42 T 06-07-2017 CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 8.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 8.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 8.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 8.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.7E-28 T 06-07-2017 IPR002347 Short-chain dehydrogenase/reductase SDR CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 Gene3D G3DSA:3.40.50.720 2 257 2.4E-63 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06035 1b9837f6d59829d9b346f1e7b32718b2 263 SUPERFAMILY SSF51735 2 258 3.84E-62 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS08320 e9cc558d9b191e76df8bf424f3182e9a 223 Pfam PF01794 Ferric reductase like transmembrane component 57 169 1.5E-14 T 06-07-2017 IPR013130 Ferric reductase transmembrane component-like domain CAL12_RS08320 e9cc558d9b191e76df8bf424f3182e9a 223 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 10 209 24.587 T 06-07-2017 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 CAL12_RS26165 48bb634d60889017badbdfa347ea53ff 249 SUPERFAMILY SSF56784 28 240 9.14E-31 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26165 48bb634d60889017badbdfa347ea53ff 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 31 211 9.0E-9 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26165 48bb634d60889017badbdfa347ea53ff 249 Gene3D G3DSA:3.40.50.1000 28 241 1.5E-23 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS26165 48bb634d60889017badbdfa347ea53ff 249 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 29 210 2.2E-43 T 06-07-2017 IPR010237 Pyrimidine 5-nucleotidase CAL12_RS26165 48bb634d60889017badbdfa347ea53ff 249 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 30 212 1.2E-10 T 06-07-2017 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CAL12_RS23450 950ef707a8e2ae0ef70214894d58d29c 386 Gene3D G3DSA:3.60.130.10 56 339 6.3E-39 T 06-07-2017 CAL12_RS23450 950ef707a8e2ae0ef70214894d58d29c 386 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 85 332 6.3E-28 T 06-07-2017 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CAL12_RS23450 950ef707a8e2ae0ef70214894d58d29c 386 SUPERFAMILY SSF51197 40 348 4.58E-49 T 06-07-2017 CAL12_RS04870 acd515ea0a83c23fd4c4a256d507d2a0 338 Gene3D G3DSA:3.40.50.300 127 330 3.4E-89 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04870 acd515ea0a83c23fd4c4a256d507d2a0 338 SUPERFAMILY SSF52540 127 306 2.16E-39 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04870 acd515ea0a83c23fd4c4a256d507d2a0 338 Pfam PF02562 PhoH-like protein 128 331 4.1E-95 T 06-07-2017 IPR003714 PhoH-like protein GO:0005524 CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 Gene3D G3DSA:3.40.50.300 3 236 1.9E-61 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 SUPERFAMILY SSF52540 5 238 4.46E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 Pfam PF00005 ABC transporter 23 167 6.0E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 PIRSF PIRSF039137 2 240 1.7E-106 T 06-07-2017 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CAL12_RS17340 bc9501b1353b582f1059a9e3d50ca8ed 243 SMART SM00382 31 233 7.3E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS06060 e9b3fad01785072ec8f930d451a9de2b 102 Gene3D G3DSA:1.10.260.40 20 63 1.1E-5 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS06060 e9b3fad01785072ec8f930d451a9de2b 102 SUPERFAMILY SSF47413 13 68 3.66E-6 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 Pfam PF02540 NAD synthase 283 531 6.8E-73 T 06-07-2017 IPR022310 NAD/GMP synthase CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 Gene3D G3DSA:3.60.110.10 5 258 2.6E-59 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 PIRSF PIRSF006630 1 558 1.1E-196 T 06-07-2017 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 SUPERFAMILY SSF52402 272 539 1.91E-78 T 06-07-2017 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 SUPERFAMILY SSF56317 1 259 2.22E-59 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 TIGRFAM TIGR00552 nadE: NAD+ synthetase 289 532 1.2E-60 T 06-07-2017 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 Pfam PF00795 Carbon-nitrogen hydrolase 5 256 2.1E-25 T 06-07-2017 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CAL12_RS15945 aafd552618c4b4ad0dbb13fb4de56dd6 558 Gene3D G3DSA:3.40.50.620 270 537 1.1E-76 T 06-07-2017 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CAL12_RS19475 26db6b8b8ff114fe1372a87b578788f7 262 SMART SM01007 24 209 1.3E-58 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS19475 26db6b8b8ff114fe1372a87b578788f7 262 Gene3D G3DSA:3.40.225.10 19 234 2.5E-61 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS19475 26db6b8b8ff114fe1372a87b578788f7 262 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 25 209 3.5E-44 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS19475 26db6b8b8ff114fe1372a87b578788f7 262 SUPERFAMILY SSF53639 16 234 1.69E-59 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS19125 2dcb0b4ca4fc635b8130b5fd6d5ec21c 53 PIRSF PIRSF036466 1 53 6.5E-19 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAL12_RS19125 2dcb0b4ca4fc635b8130b5fd6d5ec21c 53 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 50 19.227 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAL12_RS19125 2dcb0b4ca4fc635b8130b5fd6d5ec21c 53 Pfam PF07043 Protein of unknown function (DUF1328) 7 43 1.1E-14 T 06-07-2017 IPR009760 Protein of unknown function DUF1328 GO:0005886 CAL12_RS06360 14059454e339a1f0a95075955e09be4d 255 SUPERFAMILY SSF52096 3 254 1.99E-79 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS06360 14059454e339a1f0a95075955e09be4d 255 Gene3D G3DSA:3.90.226.10 3 194 6.6E-61 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS06360 14059454e339a1f0a95075955e09be4d 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 5.3E-60 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS06360 14059454e339a1f0a95075955e09be4d 255 Gene3D G3DSA:1.10.12.10 197 255 1.9E-18 T 06-07-2017 IPR014748 Crontonase, C-terminal CAL12_RS06360 14059454e339a1f0a95075955e09be4d 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS23205 fc60f4bfba8a8b3005741823ddbc5d45 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 273 3.1E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS16595 e8f3a09afc1642c29ca8b5b1ab55f59f 271 SUPERFAMILY SSF52096 3 242 7.07E-66 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS16595 e8f3a09afc1642c29ca8b5b1ab55f59f 271 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 240 7.5E-49 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS16595 e8f3a09afc1642c29ca8b5b1ab55f59f 271 Gene3D G3DSA:3.90.226.10 4 266 7.9E-67 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14715 a5d29e64a46453312b1fa742e276ce3b 361 SUPERFAMILY SSF53850 147 321 5.97E-6 T 06-07-2017 CAL12_RS14715 a5d29e64a46453312b1fa742e276ce3b 361 PIRSF PIRSF017082 29 359 4.6E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14715 a5d29e64a46453312b1fa742e276ce3b 361 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 82 355 9.1E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02240 75e338313a533dac25de434567c6c12b 194 SMART SM00644 22 170 9.5E-50 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS02240 75e338313a533dac25de434567c6c12b 194 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 33 171 2.6E-19 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS02240 75e338313a533dac25de434567c6c12b 194 Gene3D G3DSA:3.40.80.10 16 178 9.4E-64 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS02240 75e338313a533dac25de434567c6c12b 194 SUPERFAMILY SSF55846 16 180 8.51E-61 T 06-07-2017 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 CAL12_RS05985 2f59d48f79e47b10b8c6526146cee9f0 352 SUPERFAMILY SSF56935 227 352 3.97E-5 T 06-07-2017 CAL12_RS05985 2f59d48f79e47b10b8c6526146cee9f0 352 SUPERFAMILY SSF56935 155 199 3.97E-5 T 06-07-2017 CAL12_RS05985 2f59d48f79e47b10b8c6526146cee9f0 352 Pfam PF04338 Protein of unknown function, DUF481 147 337 8.7E-32 T 06-07-2017 IPR007433 Protein of unknown function DUF481 CAL12_RS12140 66d7cf51ef99518a91f7da1c68e262a0 287 Pfam PF01148 Cytidylyltransferase family 4 282 5.4E-52 T 06-07-2017 CAL12_RS12140 66d7cf51ef99518a91f7da1c68e262a0 287 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 244 270 - T 06-07-2017 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 CAL12_RS15635 056c8e29aa17743f916c14f260f22479 331 SUPERFAMILY SSF53850 29 136 1.94E-28 T 06-07-2017 CAL12_RS15635 056c8e29aa17743f916c14f260f22479 331 SUPERFAMILY SSF53850 166 320 1.94E-28 T 06-07-2017 CAL12_RS15635 056c8e29aa17743f916c14f260f22479 331 Gene3D G3DSA:3.40.190.10 87 185 1.7E-10 T 06-07-2017 CAL12_RS19010 6458d1345e88241a54eed6f7480d7e35 93 Pfam PF08666 SAF domain 11 89 2.8E-6 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS19010 6458d1345e88241a54eed6f7480d7e35 93 SMART SM00858 11 89 4.7E-10 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 5.4E-20 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 5.4E-20 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 5.4E-20 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.4E-20 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 5.4E-20 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 SUPERFAMILY SSF54373 177 278 7.65E-9 T 06-07-2017 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 SUPERFAMILY SSF51905 5 172 9.33E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 SUPERFAMILY SSF51905 273 372 9.33E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 Gene3D G3DSA:3.50.50.60 273 356 1.3E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 Gene3D G3DSA:3.50.50.60 4 178 1.3E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01135 193336e690ac27d4fa1e1f097304d591 385 Pfam PF01494 FAD binding domain 7 348 3.5E-22 T 06-07-2017 IPR002938 FAD-binding domain GO:0071949 CAL12_RS24170 b013617b716795861e362b9523554307 399 Gene3D G3DSA:3.30.1540.10 224 306 2.9E-25 T 06-07-2017 CAL12_RS24170 b013617b716795861e362b9523554307 399 Pfam PF02515 CoA-transferase family III 5 375 2.0E-123 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS24170 b013617b716795861e362b9523554307 399 Gene3D G3DSA:3.40.50.10540 2 218 3.0E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS24170 b013617b716795861e362b9523554307 399 Gene3D G3DSA:3.40.50.10540 307 399 3.0E-108 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS24170 b013617b716795861e362b9523554307 399 SUPERFAMILY SSF89796 1 399 1.44E-128 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS10470 85c35f77fcc9807303eccf3f05dbb9b7 394 Pfam PF13343 Bacterial extracellular solute-binding protein 128 375 3.0E-33 T 06-07-2017 CAL12_RS10470 85c35f77fcc9807303eccf3f05dbb9b7 394 Gene3D G3DSA:3.40.190.10 315 360 2.0E-12 T 06-07-2017 CAL12_RS10470 85c35f77fcc9807303eccf3f05dbb9b7 394 Gene3D G3DSA:3.40.190.10 53 177 2.0E-12 T 06-07-2017 CAL12_RS10470 85c35f77fcc9807303eccf3f05dbb9b7 394 Gene3D G3DSA:3.40.190.10 180 314 3.1E-25 T 06-07-2017 CAL12_RS10470 85c35f77fcc9807303eccf3f05dbb9b7 394 SUPERFAMILY SSF53850 79 389 1.59E-52 T 06-07-2017 CAL12_RS22310 fa05fbbd5219c24c35bcf23be557cef2 425 Pfam PF11737 Protein of unknown function (DUF3300) 42 278 2.0E-92 T 06-07-2017 IPR021728 Protein of unknown function DUF3300 CAL12_RS02740 fb2a08d37cd29639c2d7670026ae2b53 149 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 12 140 5.6E-28 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS18365 d91711d6e1b16f26202c679129c66a34 290 Pfam PF01774 UreD urease accessory protein 60 263 2.1E-48 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAL12_RS18365 d91711d6e1b16f26202c679129c66a34 290 Hamap MF_01384 Urease accessory protein UreD [ureD]. 16 274 29.068 T 06-07-2017 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CAL12_RS13535 59aeffd2975538c1ea89b85fb7d9505c 194 Pfam PF13649 Methyltransferase domain 42 139 1.3E-14 T 06-07-2017 CAL12_RS13535 59aeffd2975538c1ea89b85fb7d9505c 194 SUPERFAMILY SSF53335 2 149 3.38E-28 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS13535 59aeffd2975538c1ea89b85fb7d9505c 194 Gene3D G3DSA:3.40.50.150 2 171 5.4E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 Gene3D G3DSA:1.10.150.130 4 127 2.2E-23 T 06-07-2017 IPR023109 Integrase/recombinase, N-terminal CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 Pfam PF00589 Phage integrase family 136 312 6.1E-19 T 06-07-2017 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 Gene3D G3DSA:1.10.443.10 132 312 1.8E-48 T 06-07-2017 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 SUPERFAMILY SSF47823 78 126 1.06E-11 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 SUPERFAMILY SSF47823 5 49 1.06E-11 T 06-07-2017 IPR010998 Integrase, Lambda-type, N-terminal CAL12_RS14770 00232a08391c22be4b2b5e7a00e56d40 330 SUPERFAMILY SSF56349 131 325 1.97E-41 T 06-07-2017 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CAL12_RS27025 3944966067fecb30789e6694aa5622dc 370 Pfam PF00953 Glycosyl transferase family 4 78 234 1.3E-26 T 06-07-2017 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 Pfam PF13378 Enolase C-terminal domain-like 165 376 9.9E-41 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 Gene3D G3DSA:3.20.20.120 122 383 4.5E-61 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 SUPERFAMILY SSF54826 2 139 1.61E-27 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 Gene3D G3DSA:3.30.390.10 1 121 2.5E-45 T 06-07-2017 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 SUPERFAMILY SSF51604 123 383 3.07E-56 T 06-07-2017 IPR029065 Enolase C-terminal domain-like CAL12_RS22865 8d92cd0ea70b1bdd09bca98362bda569 388 SMART SM00922 162 259 2.5E-18 T 06-07-2017 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CAL12_RS25490 7392a8cd3ebc359732b0a457f1abe23c 306 SUPERFAMILY SSF103481 38 142 9.68E-14 T 06-07-2017 CAL12_RS25490 7392a8cd3ebc359732b0a457f1abe23c 306 SUPERFAMILY SSF103481 196 290 1.83E-11 T 06-07-2017 CAL12_RS25490 7392a8cd3ebc359732b0a457f1abe23c 306 Pfam PF00892 EamA-like transporter family 153 289 6.1E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS25490 7392a8cd3ebc359732b0a457f1abe23c 306 Pfam PF00892 EamA-like transporter family 7 138 1.9E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS09370 5ff46a3bcdca7eec35578574c27c45b4 52 Pfam PF11752 Protein of unknown function (DUF3309) 4 52 2.2E-24 T 06-07-2017 IPR021738 Protein of unknown function DUF3309 CAL12_RS10460 34e78c8caf5c23de4bf2c19721393457 310 Gene3D G3DSA:3.20.20.370 9 309 1.7E-101 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS10460 34e78c8caf5c23de4bf2c19721393457 310 Pfam PF01522 Polysaccharide deacetylase 79 188 2.5E-11 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS10460 34e78c8caf5c23de4bf2c19721393457 310 SUPERFAMILY SSF88713 9 309 6.39E-88 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS10460 34e78c8caf5c23de4bf2c19721393457 310 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 9 310 3.8E-151 T 06-07-2017 IPR017625 Putative urate catabolism protein CAL12_RS07225 421f2909e737668a94ccdb4b8515f1ce 171 SUPERFAMILY SSF47240 2 150 9.93E-47 T 06-07-2017 IPR009078 Ferritin-like superfamily CAL12_RS07225 421f2909e737668a94ccdb4b8515f1ce 171 Pfam PF05974 Domain of unknown function (DUF892) 6 159 1.1E-46 T 06-07-2017 IPR010287 Domain of unknown function DUF892 CAL12_RS07225 421f2909e737668a94ccdb4b8515f1ce 171 Gene3D G3DSA:1.20.1260.10 1 159 2.1E-48 T 06-07-2017 IPR012347 Ferritin-related CAL12_RS11115 9c4c884a2975d91ff766594b8703ef5e 515 Pfam PF07364 Metallopeptidase family M81 4 294 3.2E-72 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS11115 9c4c884a2975d91ff766594b8703ef5e 515 Pfam PF07171 MlrC C-terminus 310 489 1.5E-45 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS11115 9c4c884a2975d91ff766594b8703ef5e 515 PIRSF PIRSF012702 1 509 1.2E-131 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS01655 dbbde52917f7ee1e55b8cd58ee39cc07 164 SUPERFAMILY SSF52833 21 162 1.48E-37 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS01655 dbbde52917f7ee1e55b8cd58ee39cc07 164 Gene3D G3DSA:3.40.30.10 2 162 5.3E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS01655 dbbde52917f7ee1e55b8cd58ee39cc07 164 Pfam PF08534 Redoxin 25 155 2.4E-25 T 06-07-2017 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CAL12_RS00910 d428438bbacd4f009f6cae6067ff133a 412 Gene3D G3DSA:1.20.1250.20 33 210 1.4E-22 T 06-07-2017 CAL12_RS00910 d428438bbacd4f009f6cae6067ff133a 412 Gene3D G3DSA:1.20.1250.20 235 400 7.2E-16 T 06-07-2017 CAL12_RS00910 d428438bbacd4f009f6cae6067ff133a 412 Pfam PF07690 Major Facilitator Superfamily 44 327 4.5E-31 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS00910 d428438bbacd4f009f6cae6067ff133a 412 SUPERFAMILY SSF103473 13 403 1.96E-60 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19870 1c67627c5a401fce8f99aa2f6eda9c78 259 Pfam PF09836 Putative DNA-binding domain 33 101 3.3E-20 T 06-07-2017 IPR018640 Putative DNA-binding domain, bacteria CAL12_RS27445 6373cea55245d6d1ee44d59d6c019121 75 Pfam PF13627 Prokaryotic lipoprotein-attachment site 14 32 2.2E-6 T 06-07-2017 IPR032831 Prokaryotic lipoprotein-attachment site CAL12_RS11610 d2db33071bcb4a2e4cca850fc14b02fc 286 SUPERFAMILY SSF56281 50 262 1.13E-31 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11610 d2db33071bcb4a2e4cca850fc14b02fc 286 Pfam PF00753 Metallo-beta-lactamase superfamily 60 257 4.5E-15 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11610 d2db33071bcb4a2e4cca850fc14b02fc 286 Gene3D G3DSA:3.60.15.10 48 260 1.1E-29 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS11610 d2db33071bcb4a2e4cca850fc14b02fc 286 SMART SM00849 58 258 1.7E-8 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS00255 28030b8263b87a11e48aa5b9fe6ee680 362 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 76 345 4.8E-77 T 06-07-2017 IPR031811 AlgX, SGNH hydrolase-like domain CAL12_RS00255 28030b8263b87a11e48aa5b9fe6ee680 362 Gene3D G3DSA:3.40.50.1110 152 214 8.2E-5 T 06-07-2017 IPR013830 SGNH hydrolase-type esterase domain CAL12_RS10310 d4ab2f7010741ec732b36765a761f940 230 SUPERFAMILY SSF81324 125 220 8.63E-15 T 06-07-2017 CAL12_RS10310 d4ab2f7010741ec732b36765a761f940 230 Pfam PF07885 Ion channel 172 219 4.1E-11 T 06-07-2017 IPR013099 Potassium channel domain CAL12_RS10310 d4ab2f7010741ec732b36765a761f940 230 Gene3D G3DSA:1.10.287.70 123 219 5.0E-11 T 06-07-2017 CAL12_RS03695 4b85f88bf45eee25baae2fa28353744c 450 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 421 2.9E-101 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS03695 4b85f88bf45eee25baae2fa28353744c 450 SUPERFAMILY SSF143968 303 432 5.1E-27 T 06-07-2017 CAL12_RS03695 4b85f88bf45eee25baae2fa28353744c 450 SUPERFAMILY SSF50475 5 296 9.02E-88 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS03695 4b85f88bf45eee25baae2fa28353744c 450 Gene3D G3DSA:3.40.1670.10 315 420 8.8E-22 T 06-07-2017 CAL12_RS03695 4b85f88bf45eee25baae2fa28353744c 450 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 13 399 2.5E-108 T 06-07-2017 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CAL12_RS13735 a3b3a0c72edfdfe5432b6beb6657c2dc 291 Gene3D G3DSA:3.20.20.140 5 290 1.3E-95 T 06-07-2017 CAL12_RS13735 a3b3a0c72edfdfe5432b6beb6657c2dc 291 Pfam PF04909 Amidohydrolase 23 288 7.0E-44 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS13735 a3b3a0c72edfdfe5432b6beb6657c2dc 291 SUPERFAMILY SSF51556 18 288 1.44E-76 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS24815 99473cc307c5dd8f802982691fa60b2b 276 Pfam PF12697 Alpha/beta hydrolase family 42 261 1.8E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS24815 99473cc307c5dd8f802982691fa60b2b 276 SUPERFAMILY SSF53474 33 271 4.33E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24815 99473cc307c5dd8f802982691fa60b2b 276 Gene3D G3DSA:3.40.50.1820 206 272 6.8E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24815 99473cc307c5dd8f802982691fa60b2b 276 Gene3D G3DSA:3.40.50.1820 26 150 6.8E-27 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS03580 0945ff280f80db0aca69f0863abfb8e7 623 SUPERFAMILY SSF102114 326 517 6.87E-25 T 06-07-2017 CAL12_RS03580 0945ff280f80db0aca69f0863abfb8e7 623 Pfam PF04055 Radical SAM superfamily 352 513 1.4E-10 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS03580 0945ff280f80db0aca69f0863abfb8e7 623 Gene3D G3DSA:3.80.30.20 353 540 2.1E-21 T 06-07-2017 IPR023404 Radical SAM, alpha/beta horseshoe CAL12_RS03580 0945ff280f80db0aca69f0863abfb8e7 623 SMART SM00729 349 562 9.9E-15 T 06-07-2017 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CAL12_RS02880 5c1a5ee827e691c4b8ff28f8d21d966e 284 Pfam PF03746 LamB/YcsF family 28 250 2.5E-47 T 06-07-2017 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CAL12_RS02880 5c1a5ee827e691c4b8ff28f8d21d966e 284 SUPERFAMILY SSF88713 24 260 2.37E-48 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS08490 4259a347d32be3ae6762c643bd98fd0a 320 Gene3D G3DSA:3.40.50.2000 204 298 1.1E-12 T 06-07-2017 CAL12_RS08490 4259a347d32be3ae6762c643bd98fd0a 320 SUPERFAMILY SSF53756 64 303 2.61E-17 T 06-07-2017 CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 Gene3D G3DSA:3.90.25.10 302 360 8.1E-53 T 06-07-2017 CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 Gene3D G3DSA:3.90.25.10 193 247 8.1E-53 T 06-07-2017 CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 Gene3D G3DSA:3.40.50.720 2 191 4.6E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 SUPERFAMILY SSF51735 3 352 7.04E-86 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 354 56.71 T 06-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 344 2.2E-158 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07995 e303c0502acb4feca17a03b7e1bcd1df 370 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 351 2.4E-174 T 06-07-2017 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 CAL12_RS14320 3b7e6c5f3e027ec8071b9a4eba8f9c6e 309 SUPERFAMILY SSF56784 214 301 9.89E-5 T 06-07-2017 IPR023214 HAD-like domain CAL12_RS06285 90d65cffa5cf1f7d4c7a2870b97fdbc7 338 Gene3D G3DSA:3.30.200.20 4 90 2.4E-30 T 06-07-2017 CAL12_RS06285 90d65cffa5cf1f7d4c7a2870b97fdbc7 338 Pfam PF01636 Phosphotransferase enzyme family 22 253 1.4E-34 T 06-07-2017 IPR002575 Aminoglycoside phosphotransferase CAL12_RS06285 90d65cffa5cf1f7d4c7a2870b97fdbc7 338 SUPERFAMILY SSF56112 4 323 9.33E-48 T 06-07-2017 IPR011009 Protein kinase-like domain CAL12_RS06285 90d65cffa5cf1f7d4c7a2870b97fdbc7 338 Gene3D G3DSA:3.90.1200.10 102 327 1.3E-69 T 06-07-2017 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 Pfam PF13354 Beta-lactamase enzyme family 68 275 1.1E-42 T 06-07-2017 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 Gene3D G3DSA:3.40.710.10 46 302 2.8E-101 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 78 95 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 218 233 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 235 250 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 156 180 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 120 145 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 182 207 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 PRINTS PR00118 Beta-lactamase class A signature 47 71 2.3E-62 T 06-07-2017 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CAL12_RS11570 3fa96488018b8d76aff92178b1528683 303 SUPERFAMILY SSF56601 46 298 1.23E-75 T 06-07-2017 IPR012338 Beta-lactamase/transpeptidase-like CAL12_RS25080 8bceab449c91528a59fdd9178d7c0fef 289 SMART SM00382 86 204 0.0042 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS25080 8bceab449c91528a59fdd9178d7c0fef 289 SUPERFAMILY SSF52540 25 195 8.04E-27 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS25080 8bceab449c91528a59fdd9178d7c0fef 289 Pfam PF05673 Protein of unknown function (DUF815) 36 287 5.1E-107 T 06-07-2017 IPR008533 Domain of unknown function DUF815 CAL12_RS25080 8bceab449c91528a59fdd9178d7c0fef 289 Gene3D G3DSA:3.40.50.300 59 197 2.3E-16 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS05500 aa69c6af748262921f9881a0c213a8c8 73 Pfam PF05433 Glycine zipper 2TM domain 35 72 5.9E-7 T 06-07-2017 IPR008816 Glycine zipper 2TM domain GO:0019867 CAL12_RS05500 aa69c6af748262921f9881a0c213a8c8 73 ProDom PD052686 LIPOPROTEIN INDUCIBLE OSMOTICALLY B PRECURSOR SIGNAL MEMBRANE PALMITATE TRANSMEMBRANE SURFACE 8 33 0.006 T 06-07-2017 CAL12_RS01325 a6c93c5d2f1b650d3426dd2c48c93faa 106 Pfam PF07769 psiF repeat 33 64 1.0E-12 T 06-07-2017 IPR011690 Phosphate-starvation-induced PsiF repeat CAL12_RS01325 a6c93c5d2f1b650d3426dd2c48c93faa 106 Pfam PF07769 psiF repeat 73 105 1.9E-18 T 06-07-2017 IPR011690 Phosphate-starvation-induced PsiF repeat CAL12_RS21665 73a3a9eb304c0c70f5c00626e705a7ae 150 SUPERFAMILY SSF46894 58 145 1.84E-12 T 06-07-2017 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CAL12_RS21665 73a3a9eb304c0c70f5c00626e705a7ae 150 Pfam PF00486 Transcriptional regulatory protein, C terminal 63 143 2.3E-6 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS21665 73a3a9eb304c0c70f5c00626e705a7ae 150 SMART SM00862 63 143 2.2E-8 T 06-07-2017 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CAL12_RS21665 73a3a9eb304c0c70f5c00626e705a7ae 150 Gene3D G3DSA:1.10.10.10 59 146 3.1E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS18160 b27c3f86abb266929c4af051067c88b9 410 Gene3D G3DSA:3.30.1540.10 236 318 9.5E-32 T 06-07-2017 CAL12_RS18160 b27c3f86abb266929c4af051067c88b9 410 SUPERFAMILY SSF89796 3 410 9.68E-142 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS18160 b27c3f86abb266929c4af051067c88b9 410 Pfam PF02515 CoA-transferase family III 5 386 9.4E-131 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS18160 b27c3f86abb266929c4af051067c88b9 410 Gene3D G3DSA:3.40.50.10540 319 410 7.9E-117 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS18160 b27c3f86abb266929c4af051067c88b9 410 Gene3D G3DSA:3.40.50.10540 2 230 7.9E-117 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS14995 8f65331b43036fd7fd3db7f46a6ca37d 390 Gene3D G3DSA:3.40.50.2300 50 211 8.0E-33 T 06-07-2017 CAL12_RS14995 8f65331b43036fd7fd3db7f46a6ca37d 390 Pfam PF04392 ABC transporter substrate binding protein 131 386 4.8E-16 T 06-07-2017 IPR007487 ABC transporter, substrate-binding protein CAL12_RS14995 8f65331b43036fd7fd3db7f46a6ca37d 390 Gene3D G3DSA:3.40.50.2300 212 351 1.8E-8 T 06-07-2017 CAL12_RS04100 fd633a6cf0074ce2af3c54a5d62687ac 347 SUPERFAMILY SSF53474 60 344 1.12E-22 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS04100 fd633a6cf0074ce2af3c54a5d62687ac 347 Gene3D G3DSA:3.40.50.1820 29 345 3.7E-88 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS01280 233a78fb1666ddd8c0901190fa6742e5 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 315 1.0E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01280 233a78fb1666ddd8c0901190fa6742e5 322 PIRSF PIRSF017082 1 321 1.7E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01280 233a78fb1666ddd8c0901190fa6742e5 322 SUPERFAMILY SSF53850 110 286 1.22E-12 T 06-07-2017 CAL12_RS17995 cc2c92529892d3f4f1496f07ed0ab70c 299 SUPERFAMILY SSF51197 101 228 1.81E-16 T 06-07-2017 CAL12_RS17995 cc2c92529892d3f4f1496f07ed0ab70c 299 Gene3D G3DSA:2.60.120.330 125 222 5.4E-17 T 06-07-2017 IPR027443 Isopenicillin N synthase-like CAL12_RS17995 cc2c92529892d3f4f1496f07ed0ab70c 299 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 68 222 4.7E-48 T 06-07-2017 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 CAL12_RS11390 0f00526ee9fcdb646e40c01b4c185a9e 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 133 3.2E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11350 0f00526ee9fcdb646e40c01b4c185a9e 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 133 3.2E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 SUPERFAMILY SSF51445 677 1056 4.56E-93 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Gene3D G3DSA:2.60.40.1180 1055 1141 5.6E-4 T 06-07-2017 IPR013780 Glycosyl hydrolase, all-beta CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Gene3D G3DSA:3.20.20.80 668 1054 6.5E-83 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Gene3D G3DSA:3.20.20.80 536 587 6.5E-83 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 SMART SM00642 701 1050 3.2E-6 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Pfam PF00128 Alpha amylase, catalytic domain 715 829 3.6E-5 T 06-07-2017 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Pfam PF11896 Domain of unknown function (DUF3416) 484 691 3.3E-50 T 06-07-2017 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Gene3D G3DSA:3.20.20.80 27 232 2.2E-14 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 481 1152 46.57 T 06-07-2017 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CAL12_RS16145 6cf7d812086422d2371bad616a3e9aae 1154 SUPERFAMILY SSF51445 29 232 2.2E-22 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS21030 f428a6b72f58dce25163a7740c5c8fbc 204 Pfam PF07007 Protein of unknown function (DUF1311) 100 191 2.9E-14 T 06-07-2017 IPR009739 Protein of unknown function DUF1311 CAL12_RS03805 892874963e5d745aa737f8e2629e0381 252 Gene3D G3DSA:3.40.50.300 11 249 3.7E-62 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03805 892874963e5d745aa737f8e2629e0381 252 SUPERFAMILY SSF52540 12 250 4.47E-58 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS03805 892874963e5d745aa737f8e2629e0381 252 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 12 252 1.6E-114 T 06-07-2017 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CAL12_RS03805 892874963e5d745aa737f8e2629e0381 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 4.3E-9 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS03805 892874963e5d745aa737f8e2629e0381 252 Pfam PF00005 ABC transporter 29 182 6.4E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS07905 a160698d892586d80447f8e72a2ce730 254 SUPERFAMILY SSF69118 1 248 2.3E-62 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS07905 a160698d892586d80447f8e72a2ce730 254 Pfam PF02627 Carboxymuconolactone decarboxylase family 161 231 2.8E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS07905 a160698d892586d80447f8e72a2ce730 254 Pfam PF02627 Carboxymuconolactone decarboxylase family 35 100 1.1E-6 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS07905 a160698d892586d80447f8e72a2ce730 254 Gene3D G3DSA:1.20.1290.10 24 92 6.1E-13 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS07905 a160698d892586d80447f8e72a2ce730 254 Gene3D G3DSA:1.20.1290.10 93 248 1.9E-69 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS18495 c9f6ddc5cb080b27112800e25a6140ce 339 Pfam PF09084 NMT1/THI5 like 45 259 2.4E-26 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS18495 c9f6ddc5cb080b27112800e25a6140ce 339 Gene3D G3DSA:3.40.190.10 134 248 1.5E-18 T 06-07-2017 CAL12_RS18495 c9f6ddc5cb080b27112800e25a6140ce 339 SMART SM00062 37 260 0.0054 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS18495 c9f6ddc5cb080b27112800e25a6140ce 339 Gene3D G3DSA:3.40.190.10 58 133 7.4E-5 T 06-07-2017 CAL12_RS18495 c9f6ddc5cb080b27112800e25a6140ce 339 SUPERFAMILY SSF53850 32 279 5.67E-41 T 06-07-2017 CAL12_RS02040 9d77f92be89be1828ad4d4b98e1f2aa5 258 SUPERFAMILY SSF161098 60 238 6.41E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02040 9d77f92be89be1828ad4d4b98e1f2aa5 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 251 1.7E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02040 9d77f92be89be1828ad4d4b98e1f2aa5 258 Gene3D G3DSA:1.10.3720.10 60 251 1.2E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22275 118d9a03a2bbba1f7d70c1a784e95e39 435 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 7 429 1.9E-85 T 06-07-2017 IPR005219 Conserved hypothetical protein CHP00155 CAL12_RS22275 118d9a03a2bbba1f7d70c1a784e95e39 435 Pfam PF04403 Paraquat-inducible protein A 45 198 1.2E-43 T 06-07-2017 IPR007498 Paraquat-inducible protein A CAL12_RS22275 118d9a03a2bbba1f7d70c1a784e95e39 435 Pfam PF04403 Paraquat-inducible protein A 275 430 2.8E-55 T 06-07-2017 IPR007498 Paraquat-inducible protein A CAL12_RS17325 e34dc120515ced2651635e8fdbfd6489 149 Pfam PF00692 dUTPase 17 147 2.1E-35 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAL12_RS17325 e34dc120515ced2651635e8fdbfd6489 149 TIGRFAM TIGR00576 dut: dUTP diphosphatase 11 148 2.2E-46 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAL12_RS17325 e34dc120515ced2651635e8fdbfd6489 149 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 32.789 T 06-07-2017 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 CAL12_RS17325 e34dc120515ced2651635e8fdbfd6489 149 Gene3D G3DSA:2.70.40.10 4 148 2.1E-50 T 06-07-2017 IPR029054 dUTPase-like CAL12_RS17325 e34dc120515ced2651635e8fdbfd6489 149 SUPERFAMILY SSF51283 15 148 5.89E-50 T 06-07-2017 IPR029054 dUTPase-like CAL12_RS10125 b579c0f109041905fa444a731047c5f3 146 Gene3D G3DSA:3.30.110.70 79 114 3.1E-4 T 06-07-2017 IPR002765 Uncharacterised protein family UPF0145 CAL12_RS22070 3b0c49a9567e1be0dcca47f5eb2d4937 164 Pfam PF07321 Type III secretion protein YscO 13 156 5.5E-13 T 06-07-2017 IPR009929 Type III secretion sytem,YscO CAL12_RS20220 2478880b8e7e857f9f7e6fb16e5d90c8 249 SUPERFAMILY SSF101082 39 230 5.23E-37 T 06-07-2017 IPR023220 Type IV secretion system, VirB5-domain CAL12_RS20220 2478880b8e7e857f9f7e6fb16e5d90c8 249 Pfam PF07996 Type IV secretion system proteins 39 229 1.3E-43 T 06-07-2017 IPR014158 Type IV secretion system, VirB5 CAL12_RS20220 2478880b8e7e857f9f7e6fb16e5d90c8 249 Gene3D G3DSA:1.20.58.430 39 230 3.6E-48 T 06-07-2017 IPR023220 Type IV secretion system, VirB5-domain CAL12_RS00570 894d4c00c6fcd973e99844b525a7b68e 249 Pfam PF05036 Sporulation related domain 173 247 1.4E-13 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS00570 894d4c00c6fcd973e99844b525a7b68e 249 SUPERFAMILY SSF110997 173 247 2.62E-15 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS00570 894d4c00c6fcd973e99844b525a7b68e 249 Gene3D G3DSA:3.30.70.1070 170 248 4.5E-20 T 06-07-2017 IPR007730 Sporulation-related domain GO:0042834 CAL12_RS27105 d29153a2913e4ba8d9ba82ab04618f95 401 Pfam PF00155 Aminotransferase class I and II 47 387 9.8E-33 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS27105 d29153a2913e4ba8d9ba82ab04618f95 401 Gene3D G3DSA:3.90.1150.10 277 397 1.2E-11 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS27105 d29153a2913e4ba8d9ba82ab04618f95 401 SUPERFAMILY SSF53383 10 397 2.15E-102 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS27105 d29153a2913e4ba8d9ba82ab04618f95 401 Gene3D G3DSA:3.40.640.10 64 276 1.1E-71 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS00610 bbe767c83d86f4e467abda893200fa95 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 254 9.7E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00610 bbe767c83d86f4e467abda893200fa95 271 Gene3D G3DSA:1.10.3720.10 9 264 9.1E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00610 bbe767c83d86f4e467abda893200fa95 271 SUPERFAMILY SSF161098 3 260 2.49E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05625 c345146eaa3a229f3c791376bb583eb2 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 67 342 9.8E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS02380 372f66d3f0c2576796306a33b054594b 278 SUPERFAMILY SSF161098 8 274 1.59E-47 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02380 372f66d3f0c2576796306a33b054594b 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 267 5.0E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02380 372f66d3f0c2576796306a33b054594b 278 Gene3D G3DSA:1.10.3720.10 13 273 7.2E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02930 f7ab66eef5b56978833f60f9f287073e 404 TIGRFAM TIGR00843 benE: benzoate transporter 24 395 1.3E-102 T 06-07-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CAL12_RS02930 f7ab66eef5b56978833f60f9f287073e 404 Pfam PF03594 Benzoate membrane transport protein 20 396 3.4E-128 T 06-07-2017 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 CAL12_RS23050 882a09101cce63edffe8f155a6c4ad00 113 SUPERFAMILY SSF54292 5 96 8.78E-27 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23050 882a09101cce63edffe8f155a6c4ad00 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 83 7.6E-12 T 06-07-2017 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CAL12_RS23050 882a09101cce63edffe8f155a6c4ad00 113 Gene3D G3DSA:3.10.20.30 4 97 2.0E-26 T 06-07-2017 IPR012675 Beta-grasp domain CAL12_RS03850 a7bcfbd14cca4978a1f8b1f8cc7b554d 274 SUPERFAMILY SSF56300 5 260 3.12E-59 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS03850 a7bcfbd14cca4978a1f8b1f8cc7b554d 274 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 3 257 38.306 T 06-07-2017 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CAL12_RS03850 a7bcfbd14cca4978a1f8b1f8cc7b554d 274 Gene3D G3DSA:3.60.21.10 5 252 1.1E-43 T 06-07-2017 IPR029052 Metallo-dependent phosphatase-like CAL12_RS03850 a7bcfbd14cca4978a1f8b1f8cc7b554d 274 Pfam PF00149 Calcineurin-like phosphoesterase 5 199 2.8E-20 T 06-07-2017 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 CAL12_RS03685 3a513244fd385d97f8062c7d3ffe1bbd 238 PIRSF PIRSF015736 3 238 2.2E-70 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS03685 3a513244fd385d97f8062c7d3ffe1bbd 238 Pfam PF01177 Asp/Glu/Hydantoin racemase 58 218 3.7E-7 T 06-07-2017 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CAL12_RS21955 8074dd99dcb7ed2e82e3c73c78798f0d 826 Gene3D G3DSA:1.25.40.10 586 823 4.9E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21955 8074dd99dcb7ed2e82e3c73c78798f0d 826 Gene3D G3DSA:1.25.40.10 291 473 4.2E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21955 8074dd99dcb7ed2e82e3c73c78798f0d 826 SUPERFAMILY SSF48452 587 798 9.16E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS21955 8074dd99dcb7ed2e82e3c73c78798f0d 826 SUPERFAMILY SSF48452 310 473 2.89E-9 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS07750 0f0897aa6633f1dd291fa111741de549 265 Gene3D G3DSA:3.40.50.300 4 215 2.1E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07750 0f0897aa6633f1dd291fa111741de549 265 SUPERFAMILY SSF52540 21 229 4.48E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS07750 0f0897aa6633f1dd291fa111741de549 265 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS07750 0f0897aa6633f1dd291fa111741de549 265 SMART SM00382 31 213 7.4E-13 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS07750 0f0897aa6633f1dd291fa111741de549 265 Pfam PF00005 ABC transporter 24 162 1.3E-33 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15730 a35ec88f1f07459e487b4f6289dc8ca3 322 SUPERFAMILY SSF103481 72 165 1.31E-13 T 06-07-2017 CAL12_RS15730 a35ec88f1f07459e487b4f6289dc8ca3 322 SUPERFAMILY SSF103481 213 308 4.45E-12 T 06-07-2017 CAL12_RS15730 a35ec88f1f07459e487b4f6289dc8ca3 322 Pfam PF00892 EamA-like transporter family 28 161 2.2E-10 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS15730 a35ec88f1f07459e487b4f6289dc8ca3 322 Pfam PF00892 EamA-like transporter family 171 300 3.2E-11 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS27150 484dc434aa3e25922484edd78606b067 264 Gene3D G3DSA:1.10.3720.10 10 253 1.5E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27150 484dc434aa3e25922484edd78606b067 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 254 3.4E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27150 484dc434aa3e25922484edd78606b067 264 SUPERFAMILY SSF161098 7 255 8.22E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS26590 2ccee8b73312031f392e6bc4d0002716 323 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 318 8.1E-102 T 06-07-2017 IPR007296 Domain of unknown function DUF403 CAL12_RS20825 d73b873b34e2997832ce5d5f2b3bf3f0 469 Gene3D G3DSA:3.30.1330.120 280 418 2.7E-16 T 06-07-2017 CAL12_RS20825 d73b873b34e2997832ce5d5f2b3bf3f0 469 Pfam PF03972 MmgE/PrpD family 19 437 1.2E-77 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS20825 d73b873b34e2997832ce5d5f2b3bf3f0 469 SUPERFAMILY SSF103378 17 457 1.31E-79 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS26275 9617817e236502d3ce8d3f8c61ac64db 237 Pfam PF06629 MltA-interacting protein MipA 13 237 2.8E-44 T 06-07-2017 IPR010583 MltA-interacting MipA CAL12_RS00720 ce6852ff378c7f10cee6d09c9db2b266 122 PIRSF PIRSF031804 1 114 1.1E-39 T 06-07-2017 IPR016983 Uncharacterised conserved protein UCP031804 CAL12_RS00720 ce6852ff378c7f10cee6d09c9db2b266 122 Pfam PF06803 Protein of unknown function (DUF1232) 50 84 2.6E-13 T 06-07-2017 IPR010652 Protein of unknown function DUF1232 CAL12_RS08615 e56d41bc5c1eba83a6e47df479b5c6d2 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 432 5.6E-101 T 06-07-2017 IPR000914 Solute-binding protein family 5 domain CAL12_RS08615 e56d41bc5c1eba83a6e47df479b5c6d2 519 Gene3D G3DSA:3.40.190.10 132 283 7.0E-49 T 06-07-2017 CAL12_RS08615 e56d41bc5c1eba83a6e47df479b5c6d2 519 SUPERFAMILY SSF53850 31 517 1.18E-138 T 06-07-2017 CAL12_RS08615 e56d41bc5c1eba83a6e47df479b5c6d2 519 PIRSF PIRSF002741 3 512 1.9E-112 T 06-07-2017 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CAL12_RS08615 e56d41bc5c1eba83a6e47df479b5c6d2 519 Gene3D G3DSA:3.10.105.10 284 488 8.2E-57 T 06-07-2017 CAL12_RS03045 f30b3da2ff44a4d1d4a07c1f5fd5a4ef 349 Gene3D G3DSA:1.10.1530.10 5 73 2.5E-21 T 06-07-2017 CAL12_RS03045 f30b3da2ff44a4d1d4a07c1f5fd5a4ef 349 Gene3D G3DSA:3.30.1370.60 74 276 5.3E-72 T 06-07-2017 CAL12_RS03045 f30b3da2ff44a4d1d4a07c1f5fd5a4ef 349 Pfam PF02615 Malate/L-lactate dehydrogenase 6 331 3.5E-105 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS03045 f30b3da2ff44a4d1d4a07c1f5fd5a4ef 349 SUPERFAMILY SSF89733 3 340 2.22E-97 T 06-07-2017 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS21180 8e2d77884f2c00d74b54e5399577b2d6 102 Gene3D G3DSA:3.40.50.360 1 87 1.2E-38 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS21180 8e2d77884f2c00d74b54e5399577b2d6 102 SUPERFAMILY SSF52218 1 84 1.3E-22 T 06-07-2017 IPR029039 Flavoprotein-like domain CAL12_RS09455 4bbcaa8a80b1c3c4904f13dc0f449b94 301 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 11 247 2.4E-93 T 06-07-2017 IPR014145 DNA ligase D, polymerase domain CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 SUPERFAMILY SSF54373 261 355 1.18E-9 T 06-07-2017 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 42 54 1.4E-8 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 13 25 1.4E-8 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 348 354 1.4E-8 T 06-07-2017 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-535734 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 SUPERFAMILY SSF51905 12 271 1.01E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 SUPERFAMILY SSF51905 347 362 1.01E-27 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 Gene3D G3DSA:3.50.50.60 11 270 3.8E-29 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS13430 a032dcefaccd04b2f75b0c141d1bfa9f 490 Pfam PF01266 FAD dependent oxidoreductase 14 370 2.4E-43 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS13525 a4c7446527be1fb90018a8c7a6f26784 502 Pfam PF03055 Retinal pigment epithelial membrane protein 70 501 1.1E-100 T 06-07-2017 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CAL12_RS19155 90a3010faa62f9432e8b050422c0e3d7 178 Pfam PF10634 Fe2+ transport protein 20 171 8.3E-69 T 06-07-2017 IPR018470 Periplasmic metal-binding protein Tp34-type CAL12_RS19155 90a3010faa62f9432e8b050422c0e3d7 178 PIRSF PIRSF017018 1 178 4.4E-84 T 06-07-2017 IPR018470 Periplasmic metal-binding protein Tp34-type CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 Pfam PF00083 Sugar (and other) transporter 456 559 8.7E-7 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 Gene3D G3DSA:1.20.1250.20 256 344 5.7E-27 T 06-07-2017 CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 Gene3D G3DSA:1.20.1250.20 23 233 1.6E-22 T 06-07-2017 CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 Gene3D G3DSA:1.20.1250.20 459 555 5.7E-27 T 06-07-2017 CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 SUPERFAMILY SSF103473 463 558 7.32E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 SUPERFAMILY SSF103473 18 345 7.32E-63 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS09460 32f39fbc1e4ffb679fc2c2702d7fa1ec 562 Pfam PF07690 Major Facilitator Superfamily 31 338 2.1E-26 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS19700 c2b500851551fbbc9e78b2baf938f2e9 209 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 131 152 - T 06-07-2017 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19700 c2b500851551fbbc9e78b2baf938f2e9 209 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 178 32.64 T 06-07-2017 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19700 c2b500851551fbbc9e78b2baf938f2e9 209 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 171 1.6E-41 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19700 c2b500851551fbbc9e78b2baf938f2e9 209 SUPERFAMILY SSF143243 19 191 7.98E-50 T 06-07-2017 CAL12_RS19700 c2b500851551fbbc9e78b2baf938f2e9 209 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 97 158 3.0E-23 T 06-07-2017 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS15900 cc7fc86db201b7a884b04f96c66d4751 399 Pfam PF03497 Anthrax toxin LF subunit 10 146 1.7E-23 T 06-07-2017 IPR005165 Anthrax toxin, edema factor, central GO:0005576|GO:0008294|GO:0009405 KEGG: 00230+4.6.1.1 CAL12_RS15900 cc7fc86db201b7a884b04f96c66d4751 399 SUPERFAMILY SSF81298 4 316 2.62E-28 T 06-07-2017 CAL12_RS22315 dac69abef3acb2369b2c6a55ad709376 312 Pfam PF11453 Protein of unknown function (DUF2950) 28 295 2.1E-106 T 06-07-2017 IPR021556 Protein of unknown function DUF2950 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 Pfam PF07690 Major Facilitator Superfamily 9 349 9.4E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 PRINTS PR00173 Glutamate-aspartate symporter signature 138 158 1.3E-5 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 PRINTS PR00173 Glutamate-aspartate symporter signature 382 401 1.3E-5 T 06-07-2017 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 Gene3D G3DSA:1.20.1250.20 239 417 8.2E-7 T 06-07-2017 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 Gene3D G3DSA:1.20.1250.20 3 208 7.9E-14 T 06-07-2017 CAL12_RS19570 a152c5d5ba5d576d0cd220f7b8ac96d1 438 SUPERFAMILY SSF103473 3 414 2.62E-30 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS19175 7ec50fc8e221396b16f80494959e5622 324 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 89 315 3.1E-46 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAL12_RS19175 7ec50fc8e221396b16f80494959e5622 324 Gene3D G3DSA:3.60.140.10 71 315 2.4E-86 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAL12_RS19175 7ec50fc8e221396b16f80494959e5622 324 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 81 314 6.1E-71 T 06-07-2017 IPR003730 Multi-copper polyphenol oxidoreductase, laccase CAL12_RS19175 7ec50fc8e221396b16f80494959e5622 324 SUPERFAMILY SSF64438 66 315 4.58E-72 T 06-07-2017 IPR011324 Cytotoxic necrotizing factor-like, catalytic CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Gene3D G3DSA:3.30.70.270 65 163 2.1E-35 T 06-07-2017 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Gene3D G3DSA:3.30.1490.100 240 343 2.4E-24 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 SUPERFAMILY SSF56672 1 233 6.76E-95 T 06-07-2017 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Pfam PF11798 IMS family HHH motif 165 196 8.4E-10 T 06-07-2017 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Pfam PF00817 impB/mucB/samB family 7 153 9.6E-52 T 06-07-2017 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Hamap MF_01113 DNA polymerase IV [dinB]. 1 351 37.525 T 06-07-2017 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 SUPERFAMILY SSF100879 239 338 1.38E-20 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Gene3D G3DSA:1.10.150.20 164 236 3.0E-24 T 06-07-2017 CAL12_RS10115 d1784889f0d4eb3ecf6c701ca81751ee 353 Pfam PF11799 impB/mucB/samB family C-terminal domain 234 343 8.2E-16 T 06-07-2017 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CAL12_RS27100 3faa60170f2e2851e68c374784ab737c 162 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 99 116 - T 06-07-2017 IPR000614 Free Met sulfoxide reductase conserved site CAL12_RS27100 3faa60170f2e2851e68c374784ab737c 162 SUPERFAMILY SSF55781 10 156 3.27E-41 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS27100 3faa60170f2e2851e68c374784ab737c 162 Gene3D G3DSA:3.30.450.40 9 154 6.5E-52 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS27100 3faa60170f2e2851e68c374784ab737c 162 Pfam PF13185 GAF domain 46 152 1.0E-9 T 06-07-2017 IPR003018 GAF domain GO:0005515 CAL12_RS25500 c8cc7e99fd3d710ff4b8f39e5552590f 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 42 218 8.0E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25500 c8cc7e99fd3d710ff4b8f39e5552590f 237 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 113 1.7E-21 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS25500 c8cc7e99fd3d710ff4b8f39e5552590f 237 SUPERFAMILY SSF161098 15 204 2.18E-35 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25500 c8cc7e99fd3d710ff4b8f39e5552590f 237 Gene3D G3DSA:1.10.3720.10 15 218 3.2E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21370 6bd6095daa8704470d0b52ab06d8e69e 318 SUPERFAMILY SSF53850 109 280 8.21E-14 T 06-07-2017 CAL12_RS21370 6bd6095daa8704470d0b52ab06d8e69e 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 314 8.9E-95 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21370 6bd6095daa8704470d0b52ab06d8e69e 318 PIRSF PIRSF017082 1 318 4.3E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06585 7c06694c93779e1898dccb9b36d80f28 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 324 1.7E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06585 7c06694c93779e1898dccb9b36d80f28 338 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 38 329 1.5E-91 T 06-07-2017 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CAL12_RS06585 7c06694c93779e1898dccb9b36d80f28 338 SUPERFAMILY SSF161098 45 322 4.71E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06585 7c06694c93779e1898dccb9b36d80f28 338 Gene3D G3DSA:1.10.3720.10 45 331 3.6E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS01600 5f9746976a0fd0d278d9b0ff6c8d8c63 109 Gene3D G3DSA:2.60.120.10 20 95 2.2E-6 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS01600 5f9746976a0fd0d278d9b0ff6c8d8c63 109 SUPERFAMILY SSF51182 23 94 6.12E-10 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS10690 7af5ae251699e5fbc8ff27eebb68d12c 210 SUPERFAMILY SSF52540 2 154 6.94E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS10690 7af5ae251699e5fbc8ff27eebb68d12c 210 Pfam PF13671 AAA domain 7 134 1.4E-6 T 06-07-2017 CAL12_RS10690 7af5ae251699e5fbc8ff27eebb68d12c 210 Gene3D G3DSA:3.40.50.300 4 138 8.4E-12 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 SUPERFAMILY SSF52540 5 252 4.05E-64 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 252 1.1E-10 T 06-07-2017 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 Pfam PF00005 ABC transporter 21 181 2.8E-29 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 Gene3D G3DSA:3.40.50.300 2 253 1.8E-68 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS17345 1749d4dc98f3f484fa1e30ba0e11574d 261 SMART SM00382 30 238 1.5E-8 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS22100 08cdb6293c7173916326f50ff5e503b8 122 SUPERFAMILY SSF48452 10 103 2.37E-10 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22100 08cdb6293c7173916326f50ff5e503b8 122 Gene3D G3DSA:1.25.40.10 15 118 1.8E-8 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS12095 e420945ebbf512adf94035cf8a823c97 157 SUPERFAMILY SSF158442 10 152 9.55E-25 T 06-07-2017 CAL12_RS12095 e420945ebbf512adf94035cf8a823c97 157 Gene3D G3DSA:1.20.1550.10 2 156 2.4E-26 T 06-07-2017 IPR023380 Disulphide bond formation protein DsbB-like domain CAL12_RS12095 e420945ebbf512adf94035cf8a823c97 157 Pfam PF02600 Disulfide bond formation protein DsbB 7 150 8.1E-30 T 06-07-2017 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 CAL12_RS24460 d108394d7cc39b45620da2b68e66adb7 205 Pfam PF01814 Hemerythrin HHE cation binding domain 29 142 8.0E-11 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAL12_RS24460 d108394d7cc39b45620da2b68e66adb7 205 Gene3D G3DSA:1.20.120.520 58 163 7.9E-13 T 06-07-2017 CAL12_RS06055 7fde7ca51619f2105934afa441187527 266 Gene3D G3DSA:3.20.20.150 1 258 1.2E-90 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06055 7fde7ca51619f2105934afa441187527 266 Pfam PF01261 Xylose isomerase-like TIM barrel 21 220 4.2E-30 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06055 7fde7ca51619f2105934afa441187527 266 SUPERFAMILY SSF51658 1 258 1.7E-81 T 06-07-2017 IPR013022 Xylose isomerase-like, TIM barrel domain CAL12_RS06055 7fde7ca51619f2105934afa441187527 266 PIRSF PIRSF006241 1 263 1.1E-93 T 06-07-2017 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 SUPERFAMILY SSF50891 120 250 3.22E-44 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 Gene3D G3DSA:3.30.1360.40 34 108 8.9E-15 T 06-07-2017 IPR024946 Arginine repressor C-terminal-like domain CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 39 243 1.2E-56 T 06-07-2017 IPR010016 KipI family CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 SUPERFAMILY SSF160467 34 125 5.36E-15 T 06-07-2017 CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 SMART SM00796 33 234 1.1E-87 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 Pfam PF02682 Allophanate hydrolase subunit 1 33 234 1.0E-68 T 06-07-2017 IPR003833 Carboxyltransferase domain, subdomain C and D CAL12_RS25625 6211b75080dd8b1d914615f95980889c 258 Gene3D G3DSA:2.40.100.10 120 256 4.9E-51 T 06-07-2017 IPR029000 Cyclophilin-like domain CAL12_RS11015 ad066158520e3415eefe9dc3d3c9ae43 333 Pfam PF04773 FecR protein 124 216 1.6E-19 T 06-07-2017 IPR006860 FecR protein CAL12_RS11015 ad066158520e3415eefe9dc3d3c9ae43 333 PIRSF PIRSF018266 15 330 1.8E-85 T 06-07-2017 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component CAL12_RS11015 ad066158520e3415eefe9dc3d3c9ae43 333 Pfam PF16220 Domain of unknown function (DUF4880) 23 63 5.0E-11 T 06-07-2017 IPR032623 FecR, N-terminal CAL12_RS20780 5c3e8ec04a1a387a181600416b2fcdec 323 PIRSF PIRSF017082 1 323 3.9E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20780 5c3e8ec04a1a387a181600416b2fcdec 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 9.6E-65 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20780 5c3e8ec04a1a387a181600416b2fcdec 323 SUPERFAMILY SSF53850 114 288 1.49E-10 T 06-07-2017 CAL12_RS17500 4c2ba3312ba9d5d26bf585c291e3cb22 309 Pfam PF00701 Dihydrodipicolinate synthetase family 34 280 2.1E-5 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS17500 4c2ba3312ba9d5d26bf585c291e3cb22 309 SUPERFAMILY SSF51569 15 298 4.5E-31 T 06-07-2017 CAL12_RS17500 4c2ba3312ba9d5d26bf585c291e3cb22 309 SMART SM01130 11 300 6.8E-8 T 06-07-2017 IPR002220 DapA-like GO:0008152|GO:0016829 CAL12_RS17500 4c2ba3312ba9d5d26bf585c291e3cb22 309 Gene3D G3DSA:3.20.20.70 13 300 7.3E-38 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS06665 3a025af3b0e75b88b5c66886ec054773 126 Gene3D G3DSA:3.30.429.10 3 126 1.2E-44 T 06-07-2017 CAL12_RS06665 3a025af3b0e75b88b5c66886ec054773 126 SUPERFAMILY SSF55331 2 125 1.28E-43 T 06-07-2017 IPR014347 Tautomerase/MIF superfamily CAL12_RS06665 3a025af3b0e75b88b5c66886ec054773 126 Pfam PF14552 Tautomerase enzyme 38 119 2.3E-33 T 06-07-2017 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CAL12_RS24890 cbfb211f882f739ba5b49d1834c46a41 206 Gene3D G3DSA:3.40.50.1820 2 193 7.1E-21 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24890 cbfb211f882f739ba5b49d1834c46a41 206 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 196 7.6E-46 T 06-07-2017 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA CAL12_RS24890 cbfb211f882f739ba5b49d1834c46a41 206 SUPERFAMILY SSF53474 2 195 1.06E-18 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 Gene3D G3DSA:1.10.10.10 16 83 3.6E-20 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 Pfam PF01614 Bacterial transcriptional regulator 174 240 5.6E-10 T 06-07-2017 IPR014757 Transcription regulator IclR, C-terminal CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 Pfam PF09339 IclR helix-turn-helix domain 26 77 4.3E-12 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 Gene3D G3DSA:3.30.450.40 90 242 1.1E-37 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 SUPERFAMILY SSF46785 26 94 5.44E-11 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 SUPERFAMILY SSF55781 90 242 1.9E-34 T 06-07-2017 IPR029016 GAF domain-like CAL12_RS13420 4d2c0fda884309df825a23ae60d431ba 251 SMART SM00346 24 113 3.0E-15 T 06-07-2017 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CAL12_RS02200 621f6ec142017dd53127c9d52df09c27 393 Gene3D G3DSA:3.20.20.70 107 374 2.7E-26 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS02200 621f6ec142017dd53127c9d52df09c27 393 SUPERFAMILY SSF102114 116 374 1.7E-25 T 06-07-2017 CAL12_RS02200 621f6ec142017dd53127c9d52df09c27 393 TIGRFAM TIGR03977 rSAM_pair_HxsC: His-Xaa-Ser system radical SAM maturase HxsC 88 378 2.5E-117 T 06-07-2017 IPR024032 His-Xaa-Ser system radical SAM maturase HxsC CAL12_RS02200 621f6ec142017dd53127c9d52df09c27 393 Pfam PF04055 Radical SAM superfamily 118 264 3.3E-11 T 06-07-2017 IPR007197 Radical SAM GO:0003824|GO:0051536 CAL12_RS16840 a1a65ed8e758f5688999ab864314e8b4 200 Gene3D G3DSA:1.10.10.10 4 102 2.2E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16840 a1a65ed8e758f5688999ab864314e8b4 200 Pfam PF01638 HxlR-like helix-turn-helix 20 102 7.7E-22 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS16840 a1a65ed8e758f5688999ab864314e8b4 200 SUPERFAMILY SSF46785 6 142 8.49E-29 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS13545 2fef8c44dd1c7f5e033ea0103b48516a 360 SUPERFAMILY SSF56645 54 208 3.52E-14 T 06-07-2017 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CAL12_RS13545 2fef8c44dd1c7f5e033ea0103b48516a 360 Gene3D G3DSA:2.40.110.10 124 198 2.8E-10 T 06-07-2017 CAL12_RS13390 116af1aad0decd34339eabd9b29767ef 322 PIRSF PIRSF017082 1 322 3.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13390 116af1aad0decd34339eabd9b29767ef 322 SUPERFAMILY SSF53850 93 274 5.65E-13 T 06-07-2017 CAL12_RS13390 116af1aad0decd34339eabd9b29767ef 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 318 1.1E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05740 c500f368f5be138f545df41a5e7ccbf6 427 SUPERFAMILY SSF75304 10 419 6.15E-100 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS05740 c500f368f5be138f545df41a5e7ccbf6 427 Gene3D G3DSA:3.90.1300.10 10 420 2.7E-101 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS05740 c500f368f5be138f545df41a5e7ccbf6 427 Pfam PF01425 Amidase 27 414 3.2E-64 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 SUPERFAMILY SSF56954 69 499 1.57E-104 T 06-07-2017 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 SUPERFAMILY SSF56954 16 40 1.57E-104 T 06-07-2017 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 497 4.1E-99 T 06-07-2017 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 Pfam PF02321 Outer membrane efflux protein 78 285 5.4E-32 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 Pfam PF02321 Outer membrane efflux protein 314 495 2.8E-21 T 06-07-2017 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 CAL12_RS13020 e965b4d93b6c2b9c058ce8592005ca4c 502 Gene3D G3DSA:1.20.1600.10 64 500 1.2E-104 T 06-07-2017 CAL12_RS02160 30a9869d26acdb3db6695ea9813c56a7 226 Pfam PF10099 Anti-sigma-K factor rskA 62 221 6.2E-28 T 06-07-2017 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CAL12_RS12855 4ddba210c1a29f06762a36c245b6b38e 103 Gene3D G3DSA:2.102.10.10 1 102 1.3E-33 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12855 4ddba210c1a29f06762a36c245b6b38e 103 Pfam PF00355 Rieske [2Fe-2S] domain 2 89 2.9E-20 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12855 4ddba210c1a29f06762a36c245b6b38e 103 SUPERFAMILY SSF50022 1 101 4.71E-32 T 06-07-2017 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CAL12_RS12250 76bbecbbf9ff649297b8ddbafc96fd66 393 Pfam PF16113 Enoyl-CoA hydratase/isomerase 18 375 1.4E-112 T 06-07-2017 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CAL12_RS12250 76bbecbbf9ff649297b8ddbafc96fd66 393 SUPERFAMILY SSF52096 17 203 7.04E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12250 76bbecbbf9ff649297b8ddbafc96fd66 393 SUPERFAMILY SSF52096 290 360 7.04E-62 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12250 76bbecbbf9ff649297b8ddbafc96fd66 393 Gene3D G3DSA:3.90.226.10 17 209 8.7E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS12250 76bbecbbf9ff649297b8ddbafc96fd66 393 Gene3D G3DSA:3.90.226.10 290 358 8.7E-51 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS15660 32e8ae3c430dcca4e429aedb0ee845fa 329 Gene3D G3DSA:3.40.190.10 236 266 2.1E-8 T 06-07-2017 CAL12_RS15660 32e8ae3c430dcca4e429aedb0ee845fa 329 Gene3D G3DSA:3.40.190.10 115 193 2.1E-8 T 06-07-2017 CAL12_RS15660 32e8ae3c430dcca4e429aedb0ee845fa 329 SUPERFAMILY SSF53850 44 259 2.0E-23 T 06-07-2017 CAL12_RS15660 32e8ae3c430dcca4e429aedb0ee845fa 329 Pfam PF09084 NMT1/THI5 like 45 251 6.3E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS04400 c59cd327031f0437252f68bc688ee734 380 Pfam PF07394 Protein of unknown function (DUF1501) 31 355 1.3E-32 T 06-07-2017 IPR010869 Protein of unknown function DUF1501 CAL12_RS19490 2d3fe151db12479957dbfd73d066226c 310 Pfam PF06675 Protein of unknown function (DUF1177) 40 309 9.8E-135 T 06-07-2017 IPR009561 Protein of unknown function DUF1177 CAL12_RS15780 eb52e2da4c5ac14506a0d1cbb120973f 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 376 1.8E-82 T 06-07-2017 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 CAL12_RS15780 eb52e2da4c5ac14506a0d1cbb120973f 396 Gene3D G3DSA:2.40.50.100 65 98 4.5E-25 T 06-07-2017 CAL12_RS15780 eb52e2da4c5ac14506a0d1cbb120973f 396 Gene3D G3DSA:2.40.50.100 173 207 4.5E-25 T 06-07-2017 CAL12_RS15780 eb52e2da4c5ac14506a0d1cbb120973f 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 295 1.6E-13 T 06-07-2017 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain CAL12_RS15780 eb52e2da4c5ac14506a0d1cbb120973f 396 SUPERFAMILY SSF111369 52 301 2.88E-86 T 06-07-2017 CAL12_RS14950 676af14d5c5630ed9576fd7e37c967ca 233 Gene3D G3DSA:2.60.40.360 18 133 1.5E-14 T 06-07-2017 IPR008962 PapD-like CAL12_RS14950 676af14d5c5630ed9576fd7e37c967ca 233 SUPERFAMILY SSF49354 13 133 4.71E-23 T 06-07-2017 IPR008962 PapD-like CAL12_RS14950 676af14d5c5630ed9576fd7e37c967ca 233 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 18 133 1.2E-18 T 06-07-2017 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 CAL12_RS23780 96ecaa34b04bb8bca9f8294c5878f939 239 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 39 142 2.0E-29 T 06-07-2017 IPR013559 YheO-like CAL12_RS23780 96ecaa34b04bb8bca9f8294c5878f939 239 Pfam PF08348 YheO-like PAS domain 39 144 5.7E-22 T 06-07-2017 IPR013559 YheO-like CAL12_RS23780 96ecaa34b04bb8bca9f8294c5878f939 239 Pfam PF13309 HTH domain 171 231 3.8E-17 T 06-07-2017 CAL12_RS08475 0d02b9ddbf8b339ed7d871df14a35625 65 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 44 3.9E-17 T 06-07-2017 IPR019239 Bacterial antitoxin of type II TA system, VapB CAL12_RS14610 c25c6128647480475746d65a29673745 63 Pfam PF08666 SAF domain 2 51 9.8E-7 T 06-07-2017 IPR013974 SAF domain Reactome: R-HSA-4085001 CAL12_RS03820 c137b1d0b53b46dfe2b75f79d66826fa 110 SMART SM00834 1 41 8.4E-14 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS03820 c137b1d0b53b46dfe2b75f79d66826fa 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 41 1.8E-14 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS03820 c137b1d0b53b46dfe2b75f79d66826fa 110 Pfam PF09723 Zinc ribbon domain 1 39 2.9E-12 T 06-07-2017 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CAL12_RS18555 b208b8fc48efa14c15cf05375326d2b8 167 Gene3D G3DSA:3.90.950.20 4 159 1.9E-43 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS18555 b208b8fc48efa14c15cf05375326d2b8 167 Pfam PF02464 Competence-damaged protein 7 156 4.2E-40 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS18555 b208b8fc48efa14c15cf05375326d2b8 167 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 9 155 1.2E-29 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS18555 b208b8fc48efa14c15cf05375326d2b8 167 SUPERFAMILY SSF142433 3 159 1.57E-42 T 06-07-2017 IPR008136 CinA, C-terminal CAL12_RS00695 7f4d31ee6ca881378e6789773903ed83 209 PIRSF PIRSF006324 1 207 1.2E-49 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS00695 7f4d31ee6ca881378e6789773903ed83 209 Pfam PF01810 LysE type translocator 15 203 9.0E-30 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS09180 ee90a39de66dcd39f5c7069352805efb 88 SUPERFAMILY SSF64307 14 87 1.31E-21 T 06-07-2017 IPR001455 TusA-like domain CAL12_RS09180 ee90a39de66dcd39f5c7069352805efb 88 Pfam PF01206 Sulfurtransferase TusA 19 84 1.0E-21 T 06-07-2017 IPR001455 TusA-like domain CAL12_RS09180 ee90a39de66dcd39f5c7069352805efb 88 Gene3D G3DSA:3.30.110.40 16 87 2.2E-26 T 06-07-2017 IPR001455 TusA-like domain CAL12_RS09180 ee90a39de66dcd39f5c7069352805efb 88 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 20 44 - T 06-07-2017 IPR001455 TusA-like domain CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.9E-21 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 Gene3D G3DSA:3.40.190.10 176 262 2.4E-24 T 06-07-2017 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 SUPERFAMILY SSF46785 1 86 2.22E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 SUPERFAMILY SSF53850 89 282 1.18E-33 T 06-07-2017 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 Pfam PF03466 LysR substrate binding domain 87 282 4.7E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 Gene3D G3DSA:3.40.190.10 88 175 6.2E-27 T 06-07-2017 CAL12_RS23290 152992dffaa3c772b6bf2a10307a9654 295 Gene3D G3DSA:1.10.10.10 1 86 3.4E-26 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS09320 184939cf60d87363d2536198a18b8cb8 146 Pfam PF07681 DoxX 26 100 1.3E-12 T 06-07-2017 IPR032808 DoxX family CAL12_RS26815 6500e662fefba1909b949ec1f3ae01c5 248 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 53 203 1.4E-7 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS26815 6500e662fefba1909b949ec1f3ae01c5 248 SUPERFAMILY SSF159594 53 208 3.92E-21 T 06-07-2017 CAL12_RS26815 6500e662fefba1909b949ec1f3ae01c5 248 Gene3D G3DSA:3.40.50.10610 11 215 2.1E-23 T 06-07-2017 IPR005586 ABC-type transport auxiliary lipoprotein component CAL12_RS16670 50fe4dc879bc96144391be14ca43fd75 324 PIRSF PIRSF017082 1 323 1.4E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16670 50fe4dc879bc96144391be14ca43fd75 324 SUPERFAMILY SSF53850 112 293 7.15E-15 T 06-07-2017 CAL12_RS16670 50fe4dc879bc96144391be14ca43fd75 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 8.0E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14485 3fe5b2a2c846ac1284ed6c1c45188d4e 260 PIRSF PIRSF015736 6 254 1.0E-70 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS12415 35a68be7f62d457a6cc7966e03561a7b 230 SUPERFAMILY SSF89562 23 182 5.76E-47 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS12415 35a68be7f62d457a6cc7966e03561a7b 230 Gene3D G3DSA:3.50.30.40 23 180 2.4E-47 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS12415 35a68be7f62d457a6cc7966e03561a7b 230 TIGRFAM TIGR02798 ligK_PcmE: 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase 5 223 6.1E-101 T 06-07-2017 IPR014165 4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase KEGG: 00362+4.1.3.17|KEGG: 00660+4.1.3.17|MetaCyc: PWY-7701 CAL12_RS12415 35a68be7f62d457a6cc7966e03561a7b 230 Pfam PF03737 Demethylmenaquinone methyltransferase 25 172 2.2E-38 T 06-07-2017 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CAL12_RS01710 e586ff4cca719d09aeb38d0cdfc86ddc 151 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAL12_RS01710 e586ff4cca719d09aeb38d0cdfc86ddc 151 Gene3D G3DSA:3.40.930.10 1 147 1.5E-39 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAL12_RS01710 e586ff4cca719d09aeb38d0cdfc86ddc 151 SUPERFAMILY SSF55804 2 146 2.35E-41 T 06-07-2017 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CAL12_RS01710 e586ff4cca719d09aeb38d0cdfc86ddc 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 147 3.9E-32 T 06-07-2017 IPR002178 PTS EIIA type-2 domain CAL12_RS11100 7bddc4509d90f4f7eab0174e3a75b56a 308 Gene3D G3DSA:3.90.470.20 51 154 2.5E-22 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS11100 7bddc4509d90f4f7eab0174e3a75b56a 308 Gene3D G3DSA:3.90.470.20 155 222 6.3E-18 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS11100 7bddc4509d90f4f7eab0174e3a75b56a 308 SUPERFAMILY SSF56214 53 139 9.42E-15 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS11100 7bddc4509d90f4f7eab0174e3a75b56a 308 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 148 225 4.8E-13 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS11100 7bddc4509d90f4f7eab0174e3a75b56a 308 SUPERFAMILY SSF56214 147 220 1.55E-17 T 06-07-2017 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CAL12_RS02935 c9546af94b6e4565234bcfa8e2896aea 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 06-07-2017 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CAL12_RS02935 c9546af94b6e4565234bcfa8e2896aea 83 Gene3D G3DSA:3.30.70.20 4 73 1.5E-18 T 06-07-2017 CAL12_RS02935 c9546af94b6e4565234bcfa8e2896aea 83 Pfam PF00037 4Fe-4S binding domain 6 25 1.2E-5 T 06-07-2017 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CAL12_RS02935 c9546af94b6e4565234bcfa8e2896aea 83 SUPERFAMILY SSF54862 5 77 5.59E-20 T 06-07-2017 CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 Pfam PF00005 ABC transporter 29 185 5.4E-30 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 PIRSF PIRSF039085 10 260 2.9E-105 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 Gene3D G3DSA:3.40.50.300 13 256 1.6E-78 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 SMART SM00382 38 233 7.1E-18 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 SUPERFAMILY SSF52540 14 255 9.15E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26305 3096e13f1ee0bcbf57a94059b06e5780 260 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS26245 197f520b4afc746d5315d9bc5f78f462 496 Pfam PF02386 Cation transport protein 313 490 1.2E-22 T 06-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CAL12_RS26245 197f520b4afc746d5315d9bc5f78f462 496 Pfam PF02386 Cation transport protein 46 279 4.0E-42 T 06-07-2017 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CAL12_RS26245 197f520b4afc746d5315d9bc5f78f462 496 PIRSF PIRSF006247 8 496 8.4E-162 T 06-07-2017 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 CAL12_RS18375 192af990d7f0039dd725778ec6654aab 200 Pfam PF04955 HupE / UreJ protein 16 197 3.4E-57 T 06-07-2017 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CAL12_RS18375 192af990d7f0039dd725778ec6654aab 200 PIRSF PIRSF016919 6 200 7.3E-56 T 06-07-2017 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein CAL12_RS04650 e96a970f1d11f62303504ae47a24951e 459 Gene3D G3DSA:3.30.1330.120 272 411 2.5E-23 T 06-07-2017 CAL12_RS04650 e96a970f1d11f62303504ae47a24951e 459 SUPERFAMILY SSF103378 12 450 9.02E-103 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS04650 e96a970f1d11f62303504ae47a24951e 459 Pfam PF03972 MmgE/PrpD family 20 431 2.9E-105 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS25590 3fe6abcfabc4c658508a05b4f0edc50f 340 Pfam PF04280 Tim44-like domain 215 333 1.3E-12 T 06-07-2017 IPR007379 Tim44-like domain CAL12_RS25590 3fe6abcfabc4c658508a05b4f0edc50f 340 SMART SM00978 205 333 1.2E-32 T 06-07-2017 IPR007379 Tim44-like domain CAL12_RS25590 3fe6abcfabc4c658508a05b4f0edc50f 340 SUPERFAMILY SSF54427 215 336 1.2E-14 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 32 133 9.2E-27 T 06-07-2017 IPR010627 Peptidase A24A, N-terminal CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 209 219 4.9E-23 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 220 231 4.9E-23 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 232 247 4.9E-23 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 152 169 4.9E-23 T 06-07-2017 IPR014032 Peptidase A24A, prepilin type IV, bacterial CAL12_RS25120 a2ce20e5dcf274c3a8f57c3b0dd550f8 288 Pfam PF01478 Type IV leader peptidase family 143 252 1.5E-23 T 06-07-2017 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CAL12_RS25780 486270102f018da0fae1265b99ba8cf6 312 Gene3D G3DSA:1.10.10.60 240 296 4.6E-6 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS25780 486270102f018da0fae1265b99ba8cf6 312 SUPERFAMILY SSF46689 241 296 1.16E-7 T 06-07-2017 IPR009057 Homeodomain-like GO:0003677 CAL12_RS07165 2cb8ee58b0ba1c842e61946f793b2a81 225 Pfam PF12385 Papain-like cysteine protease AvrRpt2 49 197 2.8E-7 T 06-07-2017 IPR022118 Peptidase C70, AvrRpt2 CAL12_RS08160 afae018e4c33747c332a7d6ca05cc618 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 5.6E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS08160 afae018e4c33747c332a7d6ca05cc618 325 SUPERFAMILY SSF53850 114 283 7.6E-9 T 06-07-2017 CAL12_RS08160 afae018e4c33747c332a7d6ca05cc618 325 PIRSF PIRSF017082 1 325 9.4E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13225 a799ee137495433fd24422856f770596 611 PIRSF PIRSF500217 133 611 1.6E-143 T 06-07-2017 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CAL12_RS13225 a799ee137495433fd24422856f770596 611 PIRSF PIRSF016636 133 611 5.0E-144 T 06-07-2017 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CAL12_RS13225 a799ee137495433fd24422856f770596 611 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 281 490 2.9E-27 T 06-07-2017 IPR004299 Membrane bound O-acyl transferase, MBOAT CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 PRINTS PR00125 ATP synthase delta subunit signature 87 101 2.0E-23 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 PRINTS PR00125 ATP synthase delta subunit signature 76 87 2.0E-23 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 2.0E-23 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 PRINTS PR00125 ATP synthase delta subunit signature 7 26 2.0E-23 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 2.0E-23 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 1.0E-37 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 2.9E-47 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 Gene3D G3DSA:1.10.520.20 2 108 5.1E-27 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 SUPERFAMILY SSF47928 3 107 8.11E-23 T 06-07-2017 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210 CAL12_RS25810 02baf602a77fb1e41abb77968dac8f8b 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 19.122 T 06-07-2017 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 CAL12_RS12975 2dcc8c7587cbd96cb9d8f76ee245d552 139 Pfam PF03061 Thioesterase superfamily 54 128 1.9E-14 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS12975 2dcc8c7587cbd96cb9d8f76ee245d552 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 134 4.0E-28 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAL12_RS12975 2dcc8c7587cbd96cb9d8f76ee245d552 139 SUPERFAMILY SSF54637 16 135 1.56E-27 T 06-07-2017 IPR029069 HotDog domain CAL12_RS12975 2dcc8c7587cbd96cb9d8f76ee245d552 139 Gene3D G3DSA:3.10.129.10 8 135 4.7E-30 T 06-07-2017 IPR029069 HotDog domain CAL12_RS27065 c9d40868cd267d2aa8d9d470204c8387 222 Pfam PF04367 Protein of unknown function (DUF502) 58 163 8.2E-37 T 06-07-2017 IPR007462 Protein of unknown function DUF502 CAL12_RS04360 93a42bd5b4560df92062a352b75a9937 470 Pfam PF03972 MmgE/PrpD family 15 452 3.6E-116 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS04360 93a42bd5b4560df92062a352b75a9937 470 Gene3D G3DSA:3.30.1330.120 280 413 1.4E-20 T 06-07-2017 CAL12_RS04360 93a42bd5b4560df92062a352b75a9937 470 SUPERFAMILY SSF103378 12 462 1.57E-112 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS19985 b16488bda7eae66308a578686de33921 255 Pfam PF06966 Protein of unknown function (DUF1295) 22 245 1.9E-64 T 06-07-2017 IPR010721 Protein of unknown function DUF1295 CAL12_RS20070 9d21781fdbcef1a68beb7a0f0628c908 340 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 44 336 1.6E-79 T 06-07-2017 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CAL12_RS20070 9d21781fdbcef1a68beb7a0f0628c908 340 Gene3D G3DSA:3.20.20.140 21 340 1.1E-79 T 06-07-2017 CAL12_RS20070 9d21781fdbcef1a68beb7a0f0628c908 340 SUPERFAMILY SSF51556 20 339 1.18E-68 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS00815 b18306fc2f78dd7bbe0b40f61944b6b8 269 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 15 268 1.6E-112 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAL12_RS00815 b18306fc2f78dd7bbe0b40f61944b6b8 269 Gene3D G3DSA:3.20.20.70 17 269 4.3E-105 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00815 b18306fc2f78dd7bbe0b40f61944b6b8 269 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 14 268 48.224 T 06-07-2017 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CAL12_RS00815 b18306fc2f78dd7bbe0b40f61944b6b8 269 Pfam PF00977 Histidine biosynthesis protein 18 251 1.6E-88 T 06-07-2017 IPR006062 Histidine biosynthesis GO:0000105 CAL12_RS00815 b18306fc2f78dd7bbe0b40f61944b6b8 269 SUPERFAMILY SSF51366 15 268 5.26E-83 T 06-07-2017 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CAL12_RS10425 a28a3a5f4f94b252c350546d5164dc9f 304 SUPERFAMILY SSF88713 15 302 8.62E-75 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS10425 a28a3a5f4f94b252c350546d5164dc9f 304 Pfam PF01522 Polysaccharide deacetylase 71 188 3.5E-13 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS10425 a28a3a5f4f94b252c350546d5164dc9f 304 Gene3D G3DSA:3.20.20.370 14 302 8.3E-84 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS12195 4a9f2bc3c9b9258a4f80c7025f19952e 276 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 276 74.388 T 06-07-2017 IPR026530 Phosphoenolpyruvate synthase regulatory protein CAL12_RS12195 4a9f2bc3c9b9258a4f80c7025f19952e 276 Pfam PF03618 Kinase/pyrophosphorylase 10 267 2.0E-78 T 06-07-2017 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 CAL12_RS02560 aec8eba50506a2605e64c54062afea29 456 SUPERFAMILY SSF53720 2 453 1.31E-149 T 06-07-2017 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CAL12_RS02560 aec8eba50506a2605e64c54062afea29 456 Pfam PF00171 Aldehyde dehydrogenase family 2 450 7.9E-150 T 06-07-2017 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS02560 aec8eba50506a2605e64c54062afea29 456 Gene3D G3DSA:3.40.605.10 2 240 5.4E-77 T 06-07-2017 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CAL12_RS02560 aec8eba50506a2605e64c54062afea29 456 Gene3D G3DSA:3.40.309.10 241 425 1.4E-63 T 06-07-2017 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.2E-23 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.2E-23 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.2E-23 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 PIRSF PIRSF004669 1 88 2.2E-26 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 TIGRFAM TIGR01403 fliQ_rel_III: type III secretion protein, HrpO family 6 84 6.7E-33 T 06-07-2017 IPR006306 Type III secretion protein HrpO GO:0006810|GO:0016021 CAL12_RS22050 b9b064c2419f7d18106373c028346a65 88 Pfam PF01313 Bacterial export proteins, family 3 8 76 1.9E-25 T 06-07-2017 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 Pfam PF01266 FAD dependent oxidoreductase 49 401 4.0E-55 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 SUPERFAMILY SSF51905 48 273 1.75E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 SUPERFAMILY SSF51905 365 431 1.75E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 Gene3D G3DSA:3.50.50.60 191 272 1.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 Gene3D G3DSA:3.50.50.60 39 138 1.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01350 2e34d62ecd2be24381bca1eacaf03d9d 445 Gene3D G3DSA:3.50.50.60 365 417 1.0E-49 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS19595 c8fd8ed3e2ea0b8ac91cf50bf1e75eca 182 Pfam PF00578 AhpC/TSA family 6 143 5.7E-24 T 06-07-2017 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS19595 c8fd8ed3e2ea0b8ac91cf50bf1e75eca 182 PIRSF PIRSF000239 1 182 5.1E-38 T 06-07-2017 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CAL12_RS19595 c8fd8ed3e2ea0b8ac91cf50bf1e75eca 182 Gene3D G3DSA:3.40.30.10 4 182 3.4E-51 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS19595 c8fd8ed3e2ea0b8ac91cf50bf1e75eca 182 SUPERFAMILY SSF52833 4 181 7.14E-44 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS08620 7d7126fdaa2d749d2f2fa6846b60ed0f 306 SUPERFAMILY SSF161098 91 288 4.41E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08620 7d7126fdaa2d749d2f2fa6846b60ed0f 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 6.1E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08620 7d7126fdaa2d749d2f2fa6846b60ed0f 306 Gene3D G3DSA:1.10.3720.10 87 298 4.2E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24985 577f75ecb390bad244700f5780049060 134 Gene3D G3DSA:3.30.1330.40 5 133 9.0E-37 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS24985 577f75ecb390bad244700f5780049060 134 SUPERFAMILY SSF55298 3 133 1.26E-32 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS24985 577f75ecb390bad244700f5780049060 134 Pfam PF01042 Endoribonuclease L-PSP 27 131 2.7E-20 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS11895 2bcb537fedbda345b5494d288a1852ef 138 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 06-07-2017 IPR019776 Flagellar basal body rod protein, conserved site CAL12_RS11895 2bcb537fedbda345b5494d288a1852ef 138 Pfam PF00460 Flagella basal body rod protein 7 36 2.3E-9 T 06-07-2017 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CAL12_RS11895 2bcb537fedbda345b5494d288a1852ef 138 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 138 2.5E-52 T 06-07-2017 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 CAL12_RS11895 2bcb537fedbda345b5494d288a1852ef 138 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 136 1.7E-14 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAL12_RS17240 4e6196ade50fd2f16b1d9e6a5b512831 399 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 395 2.7E-183 T 06-07-2017 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 CAL12_RS17240 4e6196ade50fd2f16b1d9e6a5b512831 399 Pfam PF00155 Aminotransferase class I and II 33 375 3.9E-43 T 06-07-2017 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CAL12_RS17240 4e6196ade50fd2f16b1d9e6a5b512831 399 Gene3D G3DSA:3.40.640.10 44 287 3.0E-62 T 06-07-2017 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CAL12_RS17240 4e6196ade50fd2f16b1d9e6a5b512831 399 Gene3D G3DSA:3.90.1150.10 288 397 3.3E-20 T 06-07-2017 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 CAL12_RS17240 4e6196ade50fd2f16b1d9e6a5b512831 399 SUPERFAMILY SSF53383 2 396 1.31E-87 T 06-07-2017 IPR015424 Pyridoxal phosphate-dependent transferase CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 Gene3D G3DSA:3.90.700.10 289 423 1.8E-21 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 Pfam PF00890 FAD binding domain 5 470 1.7E-46 T 06-07-2017 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 Gene3D G3DSA:3.50.50.60 428 490 1.2E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 Gene3D G3DSA:3.50.50.60 2 256 1.2E-62 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 SUPERFAMILY SSF56425 289 432 3.4E-24 T 06-07-2017 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 SUPERFAMILY SSF51905 431 491 2.45E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS01875 8623206c40e57f0a318a7c5ef0904e73 493 SUPERFAMILY SSF51905 2 266 2.45E-43 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 SUPERFAMILY SSF51905 6 226 1.38E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 SUPERFAMILY SSF51905 309 366 1.38E-41 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 SUPERFAMILY SSF54373 227 309 4.19E-10 T 06-07-2017 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Pfam PF01266 FAD dependent oxidoreductase 6 346 6.5E-46 T 06-07-2017 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Gene3D G3DSA:3.30.9.10 226 243 1.9E-5 T 06-07-2017 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Gene3D G3DSA:3.30.9.10 91 145 1.9E-5 T 06-07-2017 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Gene3D G3DSA:3.50.50.60 146 225 6.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Gene3D G3DSA:3.50.50.60 309 366 6.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS03450 e8534331d010d26f80422ed29cef20e1 376 Gene3D G3DSA:3.50.50.60 5 83 6.3E-38 T 06-07-2017 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CAL12_RS02540 00af47083fe76ecdcc83ebed5663fa38 187 Pfam PF13847 Methyltransferase domain 62 167 5.0E-12 T 06-07-2017 IPR025714 Methyltransferase domain CAL12_RS02540 00af47083fe76ecdcc83ebed5663fa38 187 SUPERFAMILY SSF53335 39 184 2.71E-33 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02540 00af47083fe76ecdcc83ebed5663fa38 187 Gene3D G3DSA:3.40.50.150 46 170 2.8E-23 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19485 844dc566504f09d612f82c6dcaa8884c 546 Pfam PF03169 OPT oligopeptide transporter protein 20 229 2.0E-11 T 06-07-2017 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CAL12_RS19485 844dc566504f09d612f82c6dcaa8884c 546 Pfam PF03169 OPT oligopeptide transporter protein 211 538 7.0E-19 T 06-07-2017 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CAL12_RS17965 4ff91e67e58977c60b969f2be4c11e10 242 Gene3D G3DSA:3.20.20.370 57 194 2.9E-31 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS17965 4ff91e67e58977c60b969f2be4c11e10 242 SUPERFAMILY SSF88713 21 215 2.3E-42 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS17965 4ff91e67e58977c60b969f2be4c11e10 242 Pfam PF01522 Polysaccharide deacetylase 57 194 1.5E-32 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 Gene3D G3DSA:3.30.565.10 311 462 1.0E-37 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 Gene3D G3DSA:1.10.287.130 233 298 6.1E-7 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 SMART SM00388 239 306 1.8E-5 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 298 1.1E-6 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 460 3.1E-20 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 SUPERFAMILY SSF47384 226 299 8.24E-10 T 06-07-2017 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 SUPERFAMILY SSF55874 305 460 2.88E-36 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 SMART SM00387 348 462 3.8E-29 T 06-07-2017 IPR003594 Histidine kinase-like ATPase, C-terminal domain CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 4.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 4.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 4.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS09640 0970a8addc67a6edcf2be785d5da9d28 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 4.5E-16 T 06-07-2017 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 139 697 1.3E-91 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 SUPERFAMILY SSF51445 628 697 7.21E-133 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 SUPERFAMILY SSF51445 159 594 7.21E-133 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 Gene3D G3DSA:3.20.20.80 157 597 2.4E-155 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 Gene3D G3DSA:3.20.20.80 632 698 2.4E-155 T 06-07-2017 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 CAL12_RS16170 e86f0dd35ccfa884e54c4d45f00ef622 710 Pfam PF02446 4-alpha-glucanotransferase 166 683 2.6E-107 T 06-07-2017 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CAL12_RS24415 c12680e17c9003eb60b00cc302fdc7b6 139 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 61 121 6.5E-16 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAL12_RS24415 c12680e17c9003eb60b00cc302fdc7b6 139 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 27 60 2.5E-10 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAL12_RS24415 c12680e17c9003eb60b00cc302fdc7b6 139 SUPERFAMILY SSF50249 18 127 8.91E-28 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS19755 9095857ea1b3e4b2b458b9580a02e53f 207 SUPERFAMILY SSF50475 10 192 1.05E-35 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS19755 9095857ea1b3e4b2b458b9580a02e53f 207 Gene3D G3DSA:2.30.110.10 1 205 4.3E-72 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS19755 9095857ea1b3e4b2b458b9580a02e53f 207 Pfam PF04299 Putative FMN-binding domain 1 167 1.0E-58 T 06-07-2017 IPR007396 Transcriptional regulator PAI 2-type CAL12_RS19755 9095857ea1b3e4b2b458b9580a02e53f 207 PIRSF PIRSF010372 1 207 4.4E-71 T 06-07-2017 IPR007396 Transcriptional regulator PAI 2-type CAL12_RS22595 9ce5dbcd8bf5a14b8c16bec6fb570932 147 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 2 142 3.2E-19 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAL12_RS19665 d64e2056ffc8d4519d532a7eb1e8a960 214 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 1.8E-32 T 06-07-2017 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS13080 da46914c11175d659ca9eaf72eb718e9 327 PIRSF PIRSF017082 1 326 1.2E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13080 da46914c11175d659ca9eaf72eb718e9 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 321 2.1E-90 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13080 da46914c11175d659ca9eaf72eb718e9 327 Gene3D G3DSA:3.40.190.10 131 230 3.6E-5 T 06-07-2017 CAL12_RS13080 da46914c11175d659ca9eaf72eb718e9 327 SUPERFAMILY SSF53850 115 290 2.3E-15 T 06-07-2017 CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 Gene3D G3DSA:3.90.1530.10 33 138 6.2E-37 T 06-07-2017 CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 SUPERFAMILY SSF110849 41 169 1.59E-29 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 216 6.8E-58 T 06-07-2017 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 SUPERFAMILY SSF109709 125 231 9.02E-35 T 06-07-2017 CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 Pfam PF02195 ParB-like nuclease domain 41 132 1.5E-25 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS27835 408fd9b2d703ecd7dfb058283871b8f6 305 SMART SM00470 39 132 6.5E-34 T 06-07-2017 IPR003115 ParB/Sulfiredoxin CAL12_RS09620 e93361c52b262b3ca731182478d00137 436 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 24 317 22.352 T 06-07-2017 IPR023679 Uncharacterised protein family UPF0761, bacterial CAL12_RS09620 e93361c52b262b3ca731182478d00137 436 Pfam PF03631 Virulence factor BrkB 41 286 4.6E-53 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS09620 e93361c52b262b3ca731182478d00137 436 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 35 286 6.8E-68 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 SUPERFAMILY SSF46785 5 89 1.14E-19 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 Gene3D G3DSA:3.40.190.10 180 265 4.5E-19 T 06-07-2017 CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 Gene3D G3DSA:3.40.190.10 95 179 2.1E-16 T 06-07-2017 CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 SUPERFAMILY SSF53850 95 293 2.17E-37 T 06-07-2017 CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 Gene3D G3DSA:1.10.10.10 5 88 1.9E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 Pfam PF03466 LysR substrate binding domain 93 293 5.1E-36 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS27965 c24d6a7a15dbdaebdfefd05cc48f776c 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 64 6.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS12740 b38048289165ca5c968e75686f8b775a 436 Pfam PF00999 Sodium/hydrogen exchanger family 11 427 1.9E-32 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS04670 a3c8cc7595864fb447d0fce324abc920 150 SUPERFAMILY SSF55729 5 133 3.6E-28 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS04670 a3c8cc7595864fb447d0fce324abc920 150 Pfam PF00583 Acetyltransferase (GNAT) family 55 129 2.0E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS04670 a3c8cc7595864fb447d0fce324abc920 150 Gene3D G3DSA:3.40.630.30 4 136 7.6E-30 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS09880 79d74f3a79e5684efb815c9ce32dabf8 115 Pfam PF04380 Membrane fusogenic activity 1 75 3.1E-23 T 06-07-2017 IPR007475 Membrane fusogenic activity CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 PIRSF PIRSF000103 1 294 4.9E-71 T 06-07-2017 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 1.6E-34 T 06-07-2017 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 6.5E-29 T 06-07-2017 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 Gene3D G3DSA:3.40.50.720 2 162 7.2E-46 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 Gene3D G3DSA:1.10.1040.10 164 292 1.5E-34 T 06-07-2017 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 SUPERFAMILY SSF48179 163 291 3.63E-31 T 06-07-2017 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CAL12_RS07435 b31e3b263abfd70068ed760923ef7b22 296 SUPERFAMILY SSF51735 2 161 3.94E-35 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11305 024a2f107fb76a8b37a0946a61770cc8 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 2.0E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 146 18.144 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 9.9E-17 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 9.9E-17 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 9.9E-17 T 06-07-2017 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 Pfam PF02416 mttA/Hcf106 family 4 49 6.8E-8 T 06-07-2017 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CAL12_RS00790 486a7b19e3429ca88c42efad792d6975 209 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 6.8E-21 T 06-07-2017 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CAL12_RS11995 fb479d2ab060cb08b166719967b2d80e 196 Pfam PF03748 Flagellar basal body-associated protein FliL 96 196 5.0E-25 T 06-07-2017 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CAL12_RS20865 98385bbd145c2dd91ab2c5d798562db1 503 Gene3D G3DSA:2.160.20.10 20 258 6.3E-20 T 06-07-2017 IPR012334 Pectin lyase fold CAL12_RS20865 98385bbd145c2dd91ab2c5d798562db1 503 SUPERFAMILY SSF51126 18 314 2.03E-24 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS20865 98385bbd145c2dd91ab2c5d798562db1 503 Pfam PF12708 Pectate lyase superfamily protein 22 206 2.3E-14 T 06-07-2017 IPR024535 Pectate lyase superfamily protein CAL12_RS11555 65c7efa2515e5f7557f6a5988f987ae6 94 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1 91 3.4E-19 T 06-07-2017 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 5 219 27.124 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 Gene3D G3DSA:3.40.50.300 7 223 3.1E-71 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 Pfam PF13500 AAA domain 7 216 6.1E-37 T 06-07-2017 CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 9 180 1.3E-40 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 SUPERFAMILY SSF52540 7 217 2.18E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04790 155e8aeb0618291ba58ff6670fb7327e 259 PIRSF PIRSF006755 4 232 1.5E-60 T 06-07-2017 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CAL12_RS05090 b63fefa0203180f15c8ad08d0bf11355 183 Pfam PF01966 HD domain 31 81 4.8E-5 T 06-07-2017 IPR006674 HD domain CAL12_RS05090 b63fefa0203180f15c8ad08d0bf11355 183 SUPERFAMILY SSF109604 22 80 1.34E-5 T 06-07-2017 CAL12_RS05775 0bea4ae9fc8ecdf8ed83f917600083d8 255 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 31 224 3.3E-53 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAL12_RS05775 0bea4ae9fc8ecdf8ed83f917600083d8 255 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 35 212 1.7E-67 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAL12_RS05775 0bea4ae9fc8ecdf8ed83f917600083d8 255 SUPERFAMILY SSF55729 3 233 2.01E-82 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS05775 0bea4ae9fc8ecdf8ed83f917600083d8 255 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 255 92.082 T 06-07-2017 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 CAL12_RS03080 a3a62d9310995c2153f189f46e09bebf 297 Pfam PF03631 Virulence factor BrkB 27 284 3.3E-56 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS03080 a3a62d9310995c2153f189f46e09bebf 297 PIRSF PIRSF035875 4 297 4.6E-71 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS03080 a3a62d9310995c2153f189f46e09bebf 297 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 23 280 8.7E-26 T 06-07-2017 IPR017039 Virulence factor BrkB CAL12_RS10335 8c477f14acd06bf844ea0f790cb07edd 230 Gene3D G3DSA:3.40.50.850 29 225 6.1E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS10335 8c477f14acd06bf844ea0f790cb07edd 230 Pfam PF00857 Isochorismatase family 36 220 3.1E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS10335 8c477f14acd06bf844ea0f790cb07edd 230 SUPERFAMILY SSF52499 20 225 4.06E-46 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS08545 fe89ba11b085a850638587ad7c3f9add 286 SUPERFAMILY SSF103481 173 276 3.4E-15 T 06-07-2017 CAL12_RS08545 fe89ba11b085a850638587ad7c3f9add 286 SUPERFAMILY SSF103481 32 129 2.09E-17 T 06-07-2017 CAL12_RS08545 fe89ba11b085a850638587ad7c3f9add 286 Pfam PF00892 EamA-like transporter family 2 126 6.1E-24 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS08545 fe89ba11b085a850638587ad7c3f9add 286 Pfam PF00892 EamA-like transporter family 138 273 4.5E-22 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS14325 06cc73bd5b033a847ddb4604579323d8 45 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 37 2.0E-11 T 06-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type CAL12_RS14325 06cc73bd5b033a847ddb4604579323d8 45 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 38 3.7E-8 T 06-07-2017 IPR004714 Cytochrome oxidase maturation protein cbb3-type CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 SUPERFAMILY SSF52096 5 315 1.57E-101 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 49.867 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 Gene3D G3DSA:3.90.226.10 57 283 1.4E-48 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 318 8.9E-147 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 1.5E-65 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS07620 9ab28132b0abdcb71dd8351012536551 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 4.5E-46 T 06-07-2017 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 CAL12_RS16935 9bc482eb49d9166580f4e6d851197ff9 143 Gene3D G3DSA:1.10.10.10 18 137 1.1E-35 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16935 9bc482eb49d9166580f4e6d851197ff9 143 SUPERFAMILY SSF46785 34 135 3.94E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS16935 9bc482eb49d9166580f4e6d851197ff9 143 Pfam PF01638 HxlR-like helix-turn-helix 40 127 2.2E-25 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS20330 d3ff58ef2299b630b3cbe3563ca66ae3 138 Gene3D G3DSA:3.40.30.10 1 75 9.0E-8 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS05350 59d15e3c2edd1a25f9aaa714c29e8d15 173 Pfam PF11008 Protein of unknown function (DUF2846) 21 114 2.4E-10 T 06-07-2017 IPR022548 Domain of unknown function DUF2846 CAL12_RS01420 41e6c16f9fba4c8e97d705320ebd403a 148 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 35 70 6.5E-14 T 06-07-2017 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CAL12_RS01420 41e6c16f9fba4c8e97d705320ebd403a 148 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 71 128 4.3E-14 T 06-07-2017 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CAL12_RS01420 41e6c16f9fba4c8e97d705320ebd403a 148 SUPERFAMILY SSF50249 18 133 3.08E-32 T 06-07-2017 IPR012340 Nucleic acid-binding, OB-fold CAL12_RS16345 7ad7339ffbfec31437b91770ec029594 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 281 1.1E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16345 7ad7339ffbfec31437b91770ec029594 296 Gene3D G3DSA:1.10.3720.10 55 282 1.7E-45 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16345 7ad7339ffbfec31437b91770ec029594 296 SUPERFAMILY SSF161098 50 274 8.5E-48 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS16250 0164f1cdeabccbfdbcdff5c61d86e2a7 828 Pfam PF02687 FtsX-like permease family 699 817 3.1E-9 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS16250 0164f1cdeabccbfdbcdff5c61d86e2a7 828 Pfam PF02687 FtsX-like permease family 246 368 2.3E-6 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS16250 0164f1cdeabccbfdbcdff5c61d86e2a7 828 Pfam PF12704 MacB-like periplasmic core domain 465 664 6.6E-10 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAL12_RS13465 f9d534c814ac1da600bd1c5da6f5c47f 297 SUPERFAMILY SSF53213 21 283 1.31E-85 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS13465 f9d534c814ac1da600bd1c5da6f5c47f 297 PIRSF PIRSF006157 18 284 4.0E-90 T 06-07-2017 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 CAL12_RS13465 f9d534c814ac1da600bd1c5da6f5c47f 297 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 24 282 7.5E-41 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS13465 f9d534c814ac1da600bd1c5da6f5c47f 297 Gene3D G3DSA:3.40.830.10 18 283 3.9E-95 T 06-07-2017 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CAL12_RS09330 996a8541ee313bc9517180bdcbb2ed63 233 Pfam PF06912 Protein of unknown function (DUF1275) 15 223 4.6E-32 T 06-07-2017 IPR010699 Protein of unknown function DUF1275 CAL12_RS07175 1229640d2c9583ffea87bd7e48542c19 164 Gene3D G3DSA:3.30.428.10 27 160 2.2E-6 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS07175 1229640d2c9583ffea87bd7e48542c19 164 SUPERFAMILY SSF54197 27 160 2.43E-6 T 06-07-2017 IPR011146 HIT-like domain GO:0003824 CAL12_RS11190 5827c8685c561972ee69bede6880ef4c 735 Pfam PF05506 Domain of unknown function (DUF756) 534 622 6.8E-23 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS11190 5827c8685c561972ee69bede6880ef4c 735 Pfam PF05506 Domain of unknown function (DUF756) 635 717 7.0E-23 T 06-07-2017 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS11190 5827c8685c561972ee69bede6880ef4c 735 Pfam PF04185 Phosphoesterase family 48 462 1.9E-106 T 06-07-2017 IPR007312 Phosphoesterase GO:0016788 CAL12_RS11190 5827c8685c561972ee69bede6880ef4c 735 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 731 2.2E-284 T 06-07-2017 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3 CAL12_RS07800 4809a47f95f0b8c36f10f8d705aa4eff 380 SUPERFAMILY SSF53822 12 373 4.37E-92 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS07800 4809a47f95f0b8c36f10f8d705aa4eff 380 Gene3D G3DSA:3.40.50.2300 128 310 1.5E-65 T 06-07-2017 CAL12_RS07800 4809a47f95f0b8c36f10f8d705aa4eff 380 Pfam PF13433 Periplasmic binding protein domain 11 371 1.7E-134 T 06-07-2017 CAL12_RS15460 1a0a9bbc8b3f935a8be4a4dbd4eb44fc 279 Gene3D G3DSA:3.60.15.10 4 268 1.3E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS15460 1a0a9bbc8b3f935a8be4a4dbd4eb44fc 279 SUPERFAMILY SSF56281 5 277 3.8E-51 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS15460 1a0a9bbc8b3f935a8be4a4dbd4eb44fc 279 SMART SM00849 55 257 4.2E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS15460 1a0a9bbc8b3f935a8be4a4dbd4eb44fc 279 Pfam PF00753 Metallo-beta-lactamase superfamily 56 257 9.8E-26 T 06-07-2017 IPR001279 Metallo-beta-lactamase CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 PIRSF PIRSF001394 1 506 3.8E-211 T 06-07-2017 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 326 487 2.0E-48 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 Pfam PF05683 Fumarase C-terminus 288 489 4.7E-82 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 Gene3D G3DSA:3.20.130.10 304 488 2.9E-73 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 Pfam PF05681 Fumarate hydratase (Fumerase) 11 284 1.4E-99 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 13 284 1.9E-63 T 06-07-2017 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CAL12_RS06365 5202004b6dba4d7202a02cb1ce5e3cd6 506 SUPERFAMILY SSF117457 319 487 3.14E-63 T 06-07-2017 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CAL12_RS00715 2bb8c518b82ac4766f68cfb93fdd1410 494 Pfam PF11067 Protein of unknown function (DUF2868) 166 472 7.8E-77 T 06-07-2017 IPR021296 Protein of unknown function DUF2868 CAL12_RS24105 6d714f89c00459217fa023bd6a0cad3f 518 SUPERFAMILY SSF75304 3 288 1.96E-111 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24105 6d714f89c00459217fa023bd6a0cad3f 518 SUPERFAMILY SSF75304 319 498 1.96E-111 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24105 6d714f89c00459217fa023bd6a0cad3f 518 Pfam PF01425 Amidase 350 485 2.1E-12 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24105 6d714f89c00459217fa023bd6a0cad3f 518 Pfam PF01425 Amidase 11 292 5.0E-81 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24105 6d714f89c00459217fa023bd6a0cad3f 518 Gene3D G3DSA:3.90.1300.10 2 502 1.6E-127 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS11545 2f04b91da414e4ad9f0eec34ba1dd55c 120 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 34 118 3.5E-27 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS25905 8c868ba928f243da68785e6cd17b2590 203 Gene3D G3DSA:3.30.460.10 97 187 3.2E-14 T 06-07-2017 CAL12_RS25905 8c868ba928f243da68785e6cd17b2590 203 SUPERFAMILY SSF46785 12 100 8.03E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25905 8c868ba928f243da68785e6cd17b2590 203 Gene3D G3DSA:1.10.10.10 13 81 1.6E-6 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25905 8c868ba928f243da68785e6cd17b2590 203 Pfam PF01909 Nucleotidyltransferase domain 109 178 1.1E-5 T 06-07-2017 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CAL12_RS25905 8c868ba928f243da68785e6cd17b2590 203 SUPERFAMILY SSF81301 100 180 1.1E-14 T 06-07-2017 CAL12_RS05745 d31e58da06edd193a80ea9aa2a2c459f 327 SUPERFAMILY SSF53850 118 284 4.02E-8 T 06-07-2017 CAL12_RS05745 d31e58da06edd193a80ea9aa2a2c459f 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 6.5E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05745 d31e58da06edd193a80ea9aa2a2c459f 327 PIRSF PIRSF017082 1 327 9.6E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11220 7fe921df9ce12bc756381032deeda231 277 Pfam PF05013 N-formylglutamate amidohydrolase 18 240 8.3E-67 T 06-07-2017 IPR007709 N-formylglutamate amidohydrolase CAL12_RS11220 7fe921df9ce12bc756381032deeda231 277 Gene3D G3DSA:3.40.630.40 8 268 1.2E-87 T 06-07-2017 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CAL12_RS11220 7fe921df9ce12bc756381032deeda231 277 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 10 269 4.5E-103 T 06-07-2017 IPR010247 N-formylglutamate deformylase CAL12_RS11220 7fe921df9ce12bc756381032deeda231 277 SUPERFAMILY SSF53187 9 269 5.74E-81 T 06-07-2017 CAL12_RS15670 e3bb8f1fcac6654235dfa6d632064dc4 275 Gene3D G3DSA:1.10.3720.10 67 266 1.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15670 e3bb8f1fcac6654235dfa6d632064dc4 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 265 1.6E-26 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15670 e3bb8f1fcac6654235dfa6d632064dc4 275 SUPERFAMILY SSF161098 71 252 3.27E-34 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS09445 befe4b99deb41a6a403ca78b7064d004 299 Pfam PF04381 Putative exonuclease, RdgC 1 296 9.0E-121 T 06-07-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 CAL12_RS09445 befe4b99deb41a6a403ca78b7064d004 299 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.488 T 06-07-2017 IPR007476 Putative exonuclease, RdgC GO:0006310 CAL12_RS24680 3049a7b5224acbd4ff5343f15edb745b 421 SUPERFAMILY SSF53300 249 357 8.16E-7 T 06-07-2017 IPR002035 von Willebrand factor, type A CAL12_RS24680 3049a7b5224acbd4ff5343f15edb745b 421 Pfam PF04285 Protein of unknown function (DUF444) 4 418 1.6E-165 T 06-07-2017 IPR006698 Uncharacterised protein family UPF0229 CAL12_RS24680 3049a7b5224acbd4ff5343f15edb745b 421 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 420 35.097 T 06-07-2017 IPR006698 Uncharacterised protein family UPF0229 CAL12_RS06810 cf4896e03c8a3dbb13b34a83170c6f09 245 SUPERFAMILY SSF53850 32 233 7.76E-31 T 06-07-2017 CAL12_RS06810 cf4896e03c8a3dbb13b34a83170c6f09 245 Gene3D G3DSA:3.40.190.10 8 139 5.0E-16 T 06-07-2017 CAL12_RS06810 cf4896e03c8a3dbb13b34a83170c6f09 245 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 232 6.1E-19 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS06810 cf4896e03c8a3dbb13b34a83170c6f09 245 SMART SM00062 20 237 2.2E-23 T 06-07-2017 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CAL12_RS11775 2442279ff0c5ffa11bb9b0cc29bf1fa1 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 17 326 1.0E-32 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11775 2442279ff0c5ffa11bb9b0cc29bf1fa1 356 Gene3D G3DSA:3.90.25.10 196 353 7.3E-39 T 06-07-2017 CAL12_RS11775 2442279ff0c5ffa11bb9b0cc29bf1fa1 356 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 10 352 4.4E-136 T 06-07-2017 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 CAL12_RS11775 2442279ff0c5ffa11bb9b0cc29bf1fa1 356 SUPERFAMILY SSF51735 13 335 1.04E-66 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS11775 2442279ff0c5ffa11bb9b0cc29bf1fa1 356 Gene3D G3DSA:3.40.50.720 10 195 5.0E-41 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS06695 43ba33d0d0c864c403f5bc2352850ad5 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 321 2.4E-57 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06695 43ba33d0d0c864c403f5bc2352850ad5 323 PIRSF PIRSF017082 3 323 1.5E-60 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06695 43ba33d0d0c864c403f5bc2352850ad5 323 SUPERFAMILY SSF53850 97 283 7.85E-12 T 06-07-2017 CAL12_RS08055 b79d0175c6f0066e91b5d6ae0ff4d931 338 PIRSF PIRSF006470 4 335 1.8E-73 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS08055 b79d0175c6f0066e91b5d6ae0ff4d931 338 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 38 291 4.8E-71 T 06-07-2017 IPR004682 TRAP transporter solute receptor, DctP family GO:0006810|GO:0030288 CAL12_RS08055 b79d0175c6f0066e91b5d6ae0ff4d931 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 311 2.2E-76 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS01395 244401641aa807fee3a41460e5c3324b 327 PIRSF PIRSF017082 1 326 3.2E-70 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01395 244401641aa807fee3a41460e5c3324b 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 322 3.3E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01395 244401641aa807fee3a41460e5c3324b 327 SUPERFAMILY SSF53850 131 285 1.34E-8 T 06-07-2017 CAL12_RS10110 03f6914328053d3d7828c1ed330c0d9c 130 Gene3D G3DSA:3.10.129.10 1 116 5.5E-33 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10110 03f6914328053d3d7828c1ed330c0d9c 130 Pfam PF03061 Thioesterase superfamily 31 106 7.9E-15 T 06-07-2017 IPR006683 Thioesterase domain Reactome: R-HSA-75105 CAL12_RS10110 03f6914328053d3d7828c1ed330c0d9c 130 SUPERFAMILY SSF54637 2 118 2.14E-31 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10110 03f6914328053d3d7828c1ed330c0d9c 130 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 2 112 7.9E-17 T 06-07-2017 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-75105 CAL12_RS02620 2f34ba5ada75a7ea4303d3c57452fb86 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 17 186 3.2E-47 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAL12_RS02620 2f34ba5ada75a7ea4303d3c57452fb86 187 Gene3D G3DSA:2.70.40.10 3 186 4.2E-67 T 06-07-2017 IPR029054 dUTPase-like CAL12_RS02620 2f34ba5ada75a7ea4303d3c57452fb86 187 SUPERFAMILY SSF51283 3 186 7.2E-52 T 06-07-2017 IPR029054 dUTPase-like CAL12_RS02620 2f34ba5ada75a7ea4303d3c57452fb86 187 Pfam PF00692 dUTPase 81 183 3.3E-7 T 06-07-2017 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 CAL12_RS02620 2f34ba5ada75a7ea4303d3c57452fb86 187 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 2 187 27.47 T 06-07-2017 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CAL12_RS08340 ea379da79112f92adbd96b1da1a5157f 189 Pfam PF02620 Uncharacterized ACR, COG1399 62 186 2.0E-20 T 06-07-2017 IPR003772 Protein of unknown function DUF177 CAL12_RS13275 bb1df6d05ade01ad25f7de8443b16aae 270 Pfam PF00285 Citrate synthase, C-terminal domain 38 238 2.0E-25 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS13275 bb1df6d05ade01ad25f7de8443b16aae 270 Gene3D G3DSA:1.10.580.10 50 115 1.9E-4 T 06-07-2017 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CAL12_RS13275 bb1df6d05ade01ad25f7de8443b16aae 270 Gene3D G3DSA:1.10.230.10 116 205 1.7E-12 T 06-07-2017 IPR016143 Citrate synthase-like, small alpha subdomain Reactome: R-HSA-163765|Reactome: R-HSA-75105 CAL12_RS13275 bb1df6d05ade01ad25f7de8443b16aae 270 SUPERFAMILY SSF48256 8 242 1.7E-42 T 06-07-2017 IPR002020 Citrate synthase GO:0046912 CAL12_RS15695 7191440ce182f04d586194c5647e3c62 235 Pfam PF00005 ABC transporter 18 162 5.7E-28 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS15695 7191440ce182f04d586194c5647e3c62 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS15695 7191440ce182f04d586194c5647e3c62 235 Gene3D G3DSA:3.40.50.300 1 232 3.1E-60 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15695 7191440ce182f04d586194c5647e3c62 235 SUPERFAMILY SSF52540 2 233 1.33E-57 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15695 7191440ce182f04d586194c5647e3c62 235 SMART SM00382 26 201 3.0E-6 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS11285 63ccfbbf8c3e901546f78af7411b0bca 165 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 88 165 5.3E-11 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11285 63ccfbbf8c3e901546f78af7411b0bca 165 Gene3D G3DSA:2.60.40.10 3 32 8.7E-4 T 06-07-2017 IPR013783 Immunoglobulin-like fold CAL12_RS23550 f74da2a92f840c3b7156efbb0fe9497f 356 SUPERFAMILY SSF51395 1 351 1.21E-111 T 06-07-2017 CAL12_RS23550 f74da2a92f840c3b7156efbb0fe9497f 356 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 327 8.4E-75 T 06-07-2017 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CAL12_RS23550 f74da2a92f840c3b7156efbb0fe9497f 356 Gene3D G3DSA:3.20.20.70 1 350 1.1E-117 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 Pfam PF00361 Proton-conducting membrane transporter 140 432 4.1E-86 T 06-07-2017 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 164 185 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 258 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 339 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 89 114 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 117 137 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 259 285 5.8E-66 T 06-07-2017 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 65 89 1.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 277 299 1.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 1.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 91 111 1.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 500 521 1.1E-13 T 06-07-2017 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 128 1.2E-25 T 06-07-2017 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19655 d634fd63dc87a189af1a274ce4e42d6b 684 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 679 8.0E-240 T 06-07-2017 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS17940 30f52948e8962876209e13975460870c 537 Gene3D G3DSA:2.60.40.1220 22 114 1.2E-17 T 06-07-2017 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like CAL12_RS17940 30f52948e8962876209e13975460870c 537 Pfam PF04234 CopC domain 23 114 1.5E-17 T 06-07-2017 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CAL12_RS17940 30f52948e8962876209e13975460870c 537 SUPERFAMILY SSF81296 22 115 8.86E-19 T 06-07-2017 IPR014756 Immunoglobulin E-set CAL12_RS17940 30f52948e8962876209e13975460870c 537 Pfam PF05425 Copper resistance protein D 306 404 1.3E-18 T 06-07-2017 IPR008457 Copper resistance protein D GO:0016021 CAL12_RS05785 fde18eb2777c074deb4895278631cbea 205 Pfam PF11161 Protein of unknown function (DUF2946) 1 194 1.5E-57 T 06-07-2017 IPR021332 Protein of unknown function DUF2944 CAL12_RS03335 6299bc5dc4433b012a22932424fc0896 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 283 4.5E-40 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS02225 6013ba75f949b2291f3e3bbdd824d597 223 SUPERFAMILY SSF51569 11 215 2.01E-54 T 06-07-2017 CAL12_RS02225 6013ba75f949b2291f3e3bbdd824d597 223 Pfam PF01081 KDPG and KHG aldolase 15 195 1.2E-27 T 06-07-2017 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CAL12_RS02225 6013ba75f949b2291f3e3bbdd824d597 223 Gene3D G3DSA:3.20.20.70 11 214 3.1E-63 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS00485 9a7d1aa83610d08d8fd12ca991aeeaae 218 Gene3D G3DSA:1.10.3720.10 12 213 6.8E-39 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00485 9a7d1aa83610d08d8fd12ca991aeeaae 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 41 212 2.5E-14 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00485 9a7d1aa83610d08d8fd12ca991aeeaae 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 2.2E-26 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS00485 9a7d1aa83610d08d8fd12ca991aeeaae 218 SUPERFAMILY SSF161098 13 198 6.41E-38 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13410 1fb8d89e65cbc3c76a020bdfa4893823 316 PIRSF PIRSF017082 1 316 8.0E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13410 1fb8d89e65cbc3c76a020bdfa4893823 316 SUPERFAMILY SSF53850 108 272 8.32E-10 T 06-07-2017 CAL12_RS13410 1fb8d89e65cbc3c76a020bdfa4893823 316 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 312 5.8E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23020 4f49b8ee0bf012d87e25f40ce8419de0 159 Gene3D G3DSA:1.20.120.520 43 149 1.1E-9 T 06-07-2017 CAL12_RS23020 4f49b8ee0bf012d87e25f40ce8419de0 159 Pfam PF01814 Hemerythrin HHE cation binding domain 14 131 3.6E-10 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAL12_RS23020 4f49b8ee0bf012d87e25f40ce8419de0 159 Pfam PF01814 Hemerythrin HHE cation binding domain 83 155 3.7E-6 T 06-07-2017 IPR012312 Haemerythrin-like Reactome: R-HSA-390471 CAL12_RS14475 900e658ae3bb83c758eaeec567e148ba 235 SUPERFAMILY SSF161098 10 201 8.76E-32 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14475 900e658ae3bb83c758eaeec567e148ba 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 207 8.8E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14475 900e658ae3bb83c758eaeec567e148ba 235 Gene3D G3DSA:1.10.3720.10 9 213 1.2E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14475 900e658ae3bb83c758eaeec567e148ba 235 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 110 2.1E-16 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 Gene3D G3DSA:3.40.47.10 145 181 2.3E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 Gene3D G3DSA:3.40.47.10 240 368 2.3E-10 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 PIRSF PIRSF000429 2 379 2.6E-25 T 06-07-2017 IPR002155 Thiolase GO:0008152|GO:0016747 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 Gene3D G3DSA:3.40.47.10 21 113 9.0E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 Gene3D G3DSA:3.40.47.10 196 221 9.0E-16 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 SUPERFAMILY SSF53901 179 316 7.13E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS01425 42c5ab4b45947e3af87f02bace9a2042 387 SUPERFAMILY SSF53901 20 117 7.13E-24 T 06-07-2017 IPR016039 Thiolase-like GO:0003824|GO:0008152 CAL12_RS05260 fbfd70b4d3d3c2fe148a067dc0ff0d0a 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 282 3.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS20450 bed9205e4322b3fe01403fcd690d3e13 423 Pfam PF07690 Major Facilitator Superfamily 27 355 6.9E-17 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS20450 bed9205e4322b3fe01403fcd690d3e13 423 Gene3D G3DSA:1.20.1250.20 28 208 5.0E-15 T 06-07-2017 CAL12_RS20450 bed9205e4322b3fe01403fcd690d3e13 423 Gene3D G3DSA:1.20.1250.20 229 416 6.2E-11 T 06-07-2017 CAL12_RS20450 bed9205e4322b3fe01403fcd690d3e13 423 SUPERFAMILY SSF103473 12 418 4.84E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS02355 bec99bec65b1ac8a52eb291035adedad 287 Pfam PF04909 Amidohydrolase 75 283 1.6E-37 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS02355 bec99bec65b1ac8a52eb291035adedad 287 SUPERFAMILY SSF51556 1 284 5.45E-57 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS02355 bec99bec65b1ac8a52eb291035adedad 287 Gene3D G3DSA:3.20.20.140 51 284 6.2E-50 T 06-07-2017 CAL12_RS13905 b2abded4ab7aceb75783bb8e53adc6b1 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.7E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13905 b2abded4ab7aceb75783bb8e53adc6b1 328 PIRSF PIRSF017082 1 328 7.9E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13905 b2abded4ab7aceb75783bb8e53adc6b1 328 SUPERFAMILY SSF53850 100 288 5.73E-13 T 06-07-2017 CAL12_RS10140 a5240cc6d5c53397889038a75de0d0a6 164 PIRSF PIRSF020565 1 153 1.7E-50 T 06-07-2017 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted CAL12_RS10140 a5240cc6d5c53397889038a75de0d0a6 164 Gene3D G3DSA:3.10.129.10 9 138 1.0E-11 T 06-07-2017 IPR029069 HotDog domain CAL12_RS10140 a5240cc6d5c53397889038a75de0d0a6 164 SUPERFAMILY SSF54637 7 144 3.54E-20 T 06-07-2017 IPR029069 HotDog domain CAL12_RS19925 1c40bd2f77ae9640c99e70c7e0511355 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 218 3.8E-20 T 06-07-2017 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 CAL12_RS19925 1c40bd2f77ae9640c99e70c7e0511355 296 Gene3D G3DSA:3.40.50.720 1 282 4.7E-43 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS19925 1c40bd2f77ae9640c99e70c7e0511355 296 SUPERFAMILY SSF51735 1 284 2.91E-47 T 06-07-2017 IPR016040 NAD(P)-binding domain CAL12_RS23220 bb5af5e7175e520acdb0a937dfa10c4e 216 Pfam PF01613 Flavin reductase like domain 22 162 5.0E-21 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS23220 bb5af5e7175e520acdb0a937dfa10c4e 216 SMART SM00903 19 172 4.2E-18 T 06-07-2017 IPR002563 Flavin reductase like domain GO:0010181 CAL12_RS23220 bb5af5e7175e520acdb0a937dfa10c4e 216 SUPERFAMILY SSF50475 1 196 2.94E-43 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS23220 bb5af5e7175e520acdb0a937dfa10c4e 216 Gene3D G3DSA:2.30.110.10 11 185 8.7E-53 T 06-07-2017 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 CAL12_RS01990 6a58437f6ef7e5fe1bdf7e74f41a1038 325 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 163 270 3.3E-9 T 06-07-2017 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CAL12_RS01990 6a58437f6ef7e5fe1bdf7e74f41a1038 325 SUPERFAMILY SSF53756 25 309 2.08E-26 T 06-07-2017 CAL12_RS01990 6a58437f6ef7e5fe1bdf7e74f41a1038 325 Gene3D G3DSA:3.40.50.2000 159 309 7.2E-19 T 06-07-2017 CAL12_RS00075 e8a989cb2f662e9eedfccb672c29f4a7 388 SUPERFAMILY SSF56796 12 387 5.36E-74 T 06-07-2017 CAL12_RS00075 e8a989cb2f662e9eedfccb672c29f4a7 388 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 377 1.6E-71 T 06-07-2017 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CAL12_RS00075 e8a989cb2f662e9eedfccb672c29f4a7 388 Gene3D G3DSA:3.40.50.1970 12 192 2.5E-32 T 06-07-2017 CAL12_RS00075 e8a989cb2f662e9eedfccb672c29f4a7 388 Gene3D G3DSA:1.20.1090.10 195 388 3.5E-35 T 06-07-2017 CAL12_RS11575 6eb28b1fe10b4e8c246b3e3e25b52c0d 265 Pfam PF00561 alpha/beta hydrolase fold 21 127 5.7E-15 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS11575 6eb28b1fe10b4e8c246b3e3e25b52c0d 265 Gene3D G3DSA:3.40.50.1820 3 260 4.7E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11575 6eb28b1fe10b4e8c246b3e3e25b52c0d 265 SUPERFAMILY SSF53474 1 260 1.77E-44 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS07315 f0832d03f1539283b353cee26b86a2ef 363 Pfam PF09084 NMT1/THI5 like 69 262 5.2E-15 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS07315 f0832d03f1539283b353cee26b86a2ef 363 Gene3D G3DSA:3.40.190.10 128 251 4.6E-13 T 06-07-2017 CAL12_RS07315 f0832d03f1539283b353cee26b86a2ef 363 SUPERFAMILY SSF53850 47 262 3.07E-35 T 06-07-2017 CAL12_RS24650 c05c833716fd8b6d399eefb1a230947d 584 SUPERFAMILY SSF53187 323 449 3.31E-16 T 06-07-2017 CAL12_RS24650 c05c833716fd8b6d399eefb1a230947d 584 Gene3D G3DSA:3.40.630.10 323 478 7.6E-13 T 06-07-2017 CAL12_RS10175 5c796988324f3959fd2d99a74e807088 309 PIRSF PIRSF028561 5 309 9.0E-108 T 06-07-2017 IPR014548 Predicted acyltransferase CAL12_RS10175 5c796988324f3959fd2d99a74e807088 309 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 95 305 5.7E-13 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAL12_RS02310 f38ddba7ce1fe4c36d2a014974fe0af2 159 SUPERFAMILY SSF54909 64 146 3.27E-7 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS02310 f38ddba7ce1fe4c36d2a014974fe0af2 159 Gene3D G3DSA:3.30.70.900 18 151 2.0E-35 T 06-07-2017 CAL12_RS05610 1584867d42ebc4e1cf6ef6d575ed8e15 150 Pfam PF05154 TM2 domain 16 51 4.3E-7 T 06-07-2017 IPR007829 TM2 domain CAL12_RS14820 5b308e15f04fddba0f4558ba02703edb 466 SUPERFAMILY SSF103378 8 449 1.44E-87 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS14820 5b308e15f04fddba0f4558ba02703edb 466 Gene3D G3DSA:3.30.1330.120 277 415 3.1E-28 T 06-07-2017 CAL12_RS14820 5b308e15f04fddba0f4558ba02703edb 466 Pfam PF03972 MmgE/PrpD family 8 438 1.2E-92 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS15155 8f9c313d547d63b8c22b2e0d3e2674ec 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 5.4E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15155 8f9c313d547d63b8c22b2e0d3e2674ec 329 PIRSF PIRSF017082 1 328 1.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15155 8f9c313d547d63b8c22b2e0d3e2674ec 329 SUPERFAMILY SSF53850 117 292 2.78E-15 T 06-07-2017 CAL12_RS17680 1b918a93ab6645e1c445ab4d10a2d9fd 112 Pfam PF05957 Bacterial protein of unknown function (DUF883) 17 106 1.7E-24 T 06-07-2017 IPR010279 Protein of unknown function DUF883, ElaB CAL12_RS17645 8a2409a7e81edd16400582d0c085e140 150 Pfam PF05239 PRC-barrel domain 38 112 3.7E-15 T 06-07-2017 IPR027275 PRC-barrel domain CAL12_RS17645 8a2409a7e81edd16400582d0c085e140 150 SUPERFAMILY SSF50346 30 149 9.81E-26 T 06-07-2017 IPR011033 PRC-barrel-like CAL12_RS17645 8a2409a7e81edd16400582d0c085e140 150 Gene3D G3DSA:2.30.30.240 39 98 4.1E-18 T 06-07-2017 CAL12_RS00885 f87a26c876a46018beb2d4f96b39e1b7 266 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 22 264 1.2E-80 T 06-07-2017 IPR003453 ABC transport permease subunit MlaE, Proteobacteria CAL12_RS00885 f87a26c876a46018beb2d4f96b39e1b7 266 Pfam PF02405 Permease MlaE 51 262 3.0E-73 T 06-07-2017 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CAL12_RS13795 de7f7cf82b3461d17ee432b4ada890e5 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 296 2.5E-13 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13795 de7f7cf82b3461d17ee432b4ada890e5 308 SUPERFAMILY SSF161098 30 305 1.5E-53 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13795 de7f7cf82b3461d17ee432b4ada890e5 308 Gene3D G3DSA:1.10.3720.10 29 295 3.1E-50 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19710 b77d09ffdb7a8419c2b422ce3748fa5b 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 1.2E-39 T 06-07-2017 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19710 b77d09ffdb7a8419c2b422ce3748fa5b 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.292 T 06-07-2017 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 Pfam PF03150 Di-haem cytochrome c peroxidase 63 242 5.5E-34 T 06-07-2017 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 Pfam PF00034 Cytochrome c 250 420 2.4E-5 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 SUPERFAMILY SSF46626 226 291 1.05E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 SUPERFAMILY SSF46626 322 421 1.05E-28 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 Gene3D G3DSA:1.10.760.10 61 246 2.4E-30 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 Gene3D G3DSA:1.10.760.10 247 425 1.7E-31 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS22465 909e31684ee715a78c2cc84c37cd39ba 440 SUPERFAMILY SSF46626 59 224 2.29E-27 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS04535 78be8ed01e3d3fd220e99d63a4deb515 515 Pfam PF08309 LVIVD repeat 219 238 0.023 T 06-07-2017 IPR013211 LVIVD CAL12_RS04535 78be8ed01e3d3fd220e99d63a4deb515 515 Pfam PF08309 LVIVD repeat 425 441 2.6 T 06-07-2017 IPR013211 LVIVD CAL12_RS06980 d5b20fa010e7b2145c5c35ee591c1fa8 299 Pfam PF04909 Amidohydrolase 36 298 1.0E-33 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS06980 d5b20fa010e7b2145c5c35ee591c1fa8 299 SUPERFAMILY SSF51556 33 298 4.15E-64 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS06980 d5b20fa010e7b2145c5c35ee591c1fa8 299 Gene3D G3DSA:3.20.20.140 32 298 5.8E-78 T 06-07-2017 CAL12_RS03250 08be7eaa91d8bcf99746b2174148cd40 416 Gene3D G3DSA:3.40.190.10 46 118 5.3E-4 T 06-07-2017 CAL12_RS03250 08be7eaa91d8bcf99746b2174148cd40 416 Gene3D G3DSA:3.40.190.10 146 349 4.2E-44 T 06-07-2017 CAL12_RS03250 08be7eaa91d8bcf99746b2174148cd40 416 SUPERFAMILY SSF53850 30 415 7.41E-74 T 06-07-2017 CAL12_RS03250 08be7eaa91d8bcf99746b2174148cd40 416 Pfam PF01547 Bacterial extracellular solute-binding protein 46 332 7.5E-44 T 06-07-2017 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 CAL12_RS08180 03877247e2cda1c9820b122542f3cab6 100 Gene3D G3DSA:3.30.70.900 1 92 3.4E-35 T 06-07-2017 CAL12_RS08180 03877247e2cda1c9820b122542f3cab6 100 SUPERFAMILY SSF54909 1 98 9.54E-25 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS09600 2011ee635123ff72ca1d091548d1e74d 346 Pfam PF02643 Uncharacterized ACR, COG1430 26 101 2.4E-9 T 06-07-2017 IPR003795 Protein of unknown function DUF192 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 13 255 2.2E-64 T 06-07-2017 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 2.2E-28 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 2.2E-28 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 2.2E-28 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 2.2E-28 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS11965 b4dec329e55dd1bf0df8bacc1ac3dc39 261 Pfam PF01311 Bacterial export proteins, family 1 14 246 2.0E-66 T 06-07-2017 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CAL12_RS25980 8439c26c9ef080abe61286999aa05265 127 Pfam PF03965 Penicillinase repressor 11 123 7.7E-21 T 06-07-2017 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CAL12_RS25980 8439c26c9ef080abe61286999aa05265 127 Gene3D G3DSA:1.10.10.10 9 84 1.1E-15 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS25980 8439c26c9ef080abe61286999aa05265 127 SUPERFAMILY SSF46785 9 123 1.36E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS08105 3de1a630bd29da55d0fd76735b7059f5 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 323 6.6E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08105 3de1a630bd29da55d0fd76735b7059f5 325 SUPERFAMILY SSF161098 106 306 1.05E-12 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08105 3de1a630bd29da55d0fd76735b7059f5 325 Gene3D G3DSA:1.10.3720.10 104 311 1.3E-10 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15510 77be345e30535928743a2cd25c86b5a1 340 Gene3D G3DSA:3.30.160.60 304 334 5.6E-14 T 06-07-2017 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 CAL12_RS15510 77be345e30535928743a2cd25c86b5a1 340 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 9 333 1.0E-79 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAL12_RS15510 77be345e30535928743a2cd25c86b5a1 340 Pfam PF02618 YceG-like family 46 330 1.4E-77 T 06-07-2017 IPR003770 Uncharacterised protein family UPF0755, YceG-like CAL12_RS25410 d6391d51ce9a842920293ec8fd693310 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 312 1.4E-93 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS25410 d6391d51ce9a842920293ec8fd693310 319 SUPERFAMILY SSF53850 110 285 1.02E-14 T 06-07-2017 CAL12_RS25410 d6391d51ce9a842920293ec8fd693310 319 PIRSF PIRSF017082 4 318 1.8E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20290 8a9cce815b92dfff9a2b59a4f8623387 573 SUPERFAMILY SSF52540 115 503 1.84E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20290 8a9cce815b92dfff9a2b59a4f8623387 573 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 120 501 9.4E-101 T 06-07-2017 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain CAL12_RS20290 8a9cce815b92dfff9a2b59a4f8623387 573 Gene3D G3DSA:1.10.8.80 196 306 3.4E-36 T 06-07-2017 CAL12_RS20290 8a9cce815b92dfff9a2b59a4f8623387 573 Gene3D G3DSA:3.40.50.300 309 496 1.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS20290 8a9cce815b92dfff9a2b59a4f8623387 573 Gene3D G3DSA:3.40.50.300 96 195 1.1E-65 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04780 e6c453329115488e29f26bb465698b13 233 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 9 208 2.7E-27 T 06-07-2017 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 Gene3D G3DSA:1.20.1050.10 88 203 1.4E-38 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 83 5.0E-14 T 06-07-2017 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 SUPERFAMILY SSF47616 89 208 3.82E-32 T 06-07-2017 IPR010987 Glutathione S-transferase, C-terminal-like CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 SUPERFAMILY SSF52833 1 83 7.18E-22 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 Pfam PF13410 Glutathione S-transferase, C-terminal domain 127 194 7.6E-11 T 06-07-2017 CAL12_RS21840 5a6abd1cbb3242a460170730eaef7c74 234 Gene3D G3DSA:3.40.30.10 1 82 2.4E-27 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10850 299c05c717e0dbc5f1c3682fca81f52a 310 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 34 306 8.6E-96 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10850 299c05c717e0dbc5f1c3682fca81f52a 310 SUPERFAMILY SSF53850 100 270 6.04E-13 T 06-07-2017 CAL12_RS10850 299c05c717e0dbc5f1c3682fca81f52a 310 PIRSF PIRSF017082 1 309 1.5E-86 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11900 4bcf9635e1fafa83ffb68b1324c33118 232 Pfam PF13860 FlgD Ig-like domain 113 186 6.6E-21 T 06-07-2017 IPR025965 FlgD Ig-like domain CAL12_RS11900 4bcf9635e1fafa83ffb68b1324c33118 232 Pfam PF13861 FlgD Tudor-like domain 88 227 4.7E-16 T 06-07-2017 IPR025963 FlgD Tudor-like domain CAL12_RS11900 4bcf9635e1fafa83ffb68b1324c33118 232 Pfam PF03963 Flagellar hook capping protein - N-terminal region 6 78 1.6E-22 T 06-07-2017 IPR005648 Flagellar hook capping protein CAL12_RS02135 60e36e3886462102af68169e2b61b853 366 Gene3D G3DSA:3.40.630.10 12 134 1.9E-21 T 06-07-2017 CAL12_RS02135 60e36e3886462102af68169e2b61b853 366 Gene3D G3DSA:3.40.630.10 189 235 1.9E-21 T 06-07-2017 CAL12_RS02135 60e36e3886462102af68169e2b61b853 366 Pfam PF10994 Protein of unknown function (DUF2817) 10 348 7.9E-113 T 06-07-2017 IPR021259 Protein of unknown function DUF2817 CAL12_RS02135 60e36e3886462102af68169e2b61b853 366 SUPERFAMILY SSF53187 189 308 3.31E-19 T 06-07-2017 CAL12_RS02135 60e36e3886462102af68169e2b61b853 366 SUPERFAMILY SSF53187 57 130 3.31E-19 T 06-07-2017 CAL12_RS18910 a1fdc5c560854826b7c3a3cd4f1be923 107 Pfam PF06305 Protein of unknown function (DUF1049) 22 84 4.7E-17 T 06-07-2017 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CAL12_RS00470 e101722047fee02445e1e60d3b0df8d2 153 Hamap MF_00598 Protein Smg [smg]. 1 153 26.751 T 06-07-2017 IPR007456 Smg CAL12_RS00470 e101722047fee02445e1e60d3b0df8d2 153 Pfam PF04361 Protein of unknown function (DUF494) 1 148 2.6E-51 T 06-07-2017 IPR007456 Smg CAL12_RS24590 7eaa22a7f7891909822c7b803a21e012 234 Gene3D G3DSA:3.40.50.1820 8 231 2.1E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS24590 7eaa22a7f7891909822c7b803a21e012 234 Pfam PF01738 Dienelactone hydrolase family 16 220 1.5E-42 T 06-07-2017 IPR002925 Dienelactone hydrolase GO:0016787 CAL12_RS24590 7eaa22a7f7891909822c7b803a21e012 234 SUPERFAMILY SSF53474 7 230 3.16E-38 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS04615 c9ee1cab122e3b6070c3a004b41e9a2c 261 Pfam PF08241 Methyltransferase domain 39 134 3.8E-22 T 06-07-2017 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CAL12_RS04615 c9ee1cab122e3b6070c3a004b41e9a2c 261 SUPERFAMILY SSF53335 1 255 1.91E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS04615 c9ee1cab122e3b6070c3a004b41e9a2c 261 Gene3D G3DSA:3.40.50.150 10 237 2.0E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 SUPERFAMILY SSF53822 31 392 6.36E-81 T 06-07-2017 IPR028082 Periplasmic binding protein-like I CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 289 302 3.1E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 54 70 3.1E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 32 48 3.1E-7 T 06-07-2017 IPR000709 Leu/Ile/Val-binding protein GO:0006865 CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 Gene3D G3DSA:3.40.50.2300 30 233 1.4E-55 T 06-07-2017 CAL12_RS01530 56589a68f3ac81b926cf780d3b07aaa5 395 Pfam PF13458 Periplasmic binding protein 31 362 9.6E-61 T 06-07-2017 IPR028081 Leucine-binding protein domain CAL12_RS06480 9ea1c72e399ba971c9f22b68de1a85e8 411 SUPERFAMILY SSF89796 2 409 4.06E-124 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06480 9ea1c72e399ba971c9f22b68de1a85e8 411 Gene3D G3DSA:3.30.1540.10 235 318 1.1E-26 T 06-07-2017 CAL12_RS06480 9ea1c72e399ba971c9f22b68de1a85e8 411 Pfam PF02515 CoA-transferase family III 4 386 3.0E-116 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS06480 9ea1c72e399ba971c9f22b68de1a85e8 411 Gene3D G3DSA:3.40.50.10540 3 229 1.1E-105 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS06480 9ea1c72e399ba971c9f22b68de1a85e8 411 Gene3D G3DSA:3.40.50.10540 319 409 1.1E-105 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS07095 092ac25988cd5da4b18d310d8a188178 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 5.2E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07095 092ac25988cd5da4b18d310d8a188178 266 SUPERFAMILY SSF161098 9 254 1.59E-56 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS07095 092ac25988cd5da4b18d310d8a188178 266 Gene3D G3DSA:1.10.3720.10 13 255 1.4E-52 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS21380 db2880f78abbd15b5fe06fa29e0a4d26 155 Pfam PF07080 Protein of unknown function (DUF1348) 4 144 5.3E-74 T 06-07-2017 IPR009783 Protein of unknown function DUF1348 CAL12_RS21380 db2880f78abbd15b5fe06fa29e0a4d26 155 SUPERFAMILY SSF54427 1 155 6.34E-82 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS21380 db2880f78abbd15b5fe06fa29e0a4d26 155 Gene3D G3DSA:3.10.450.50 12 154 4.5E-77 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS24085 3acea811bbcf637a8addf38b0c43fc77 311 SUPERFAMILY SSF161098 89 295 2.22E-17 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24085 3acea811bbcf637a8addf38b0c43fc77 311 Gene3D G3DSA:1.10.3720.10 88 307 6.6E-16 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS24085 3acea811bbcf637a8addf38b0c43fc77 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 311 2.6E-36 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS23595 c1ca5a8fd5b160009f21cf0b62c75973 450 Pfam PF05559 Protein of unknown function (DUF763) 5 360 7.5E-126 T 06-07-2017 IPR008482 Protein of unknown function DUF763 CAL12_RS17505 1d8069a962366d3aced7620486995971 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 3.5E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17505 1d8069a962366d3aced7620486995971 323 PIRSF PIRSF017082 1 322 1.7E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17505 1d8069a962366d3aced7620486995971 323 SUPERFAMILY SSF53850 111 283 1.07E-9 T 06-07-2017 CAL12_RS04900 8c8815b7ed39c85d0548690faab26686 293 SMART SM00901 61 176 6.2E-6 T 06-07-2017 IPR014966 FRG domain CAL12_RS04900 8c8815b7ed39c85d0548690faab26686 293 Pfam PF08867 FRG domain 65 171 1.5E-9 T 06-07-2017 IPR014966 FRG domain CAL12_RS10870 4a69a0e9260f1bd5f191f7bb96507158 244 SUPERFAMILY SSF55729 25 199 2.21E-37 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS10870 4a69a0e9260f1bd5f191f7bb96507158 244 Gene3D G3DSA:3.40.630.30 16 215 7.7E-57 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS10870 4a69a0e9260f1bd5f191f7bb96507158 244 Pfam PF13302 Acetyltransferase (GNAT) domain 39 175 2.6E-13 T 06-07-2017 IPR000182 GNAT domain GO:0008080 CAL12_RS26420 a1ae809e7caea7b95698f2965ea1db29 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 7.4E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS24560 954d53d6e47ffd698977ac3eb88b005d 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 2.2E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24560 954d53d6e47ffd698977ac3eb88b005d 325 PIRSF PIRSF017082 1 324 5.3E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS24560 954d53d6e47ffd698977ac3eb88b005d 325 SUPERFAMILY SSF53850 113 284 1.03E-13 T 06-07-2017 CAL12_RS12555 a7127efdfa8d0cdd53f9d08663af5156 290 Gene3D G3DSA:3.20.20.60 4 287 4.3E-86 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS12555 a7127efdfa8d0cdd53f9d08663af5156 290 SUPERFAMILY SSF51621 7 289 2.65E-90 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS12555 a7127efdfa8d0cdd53f9d08663af5156 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 14 249 2.0E-54 T 06-07-2017 CAL12_RS06175 a3947b783c375aa13e289dd9bfdbc347 320 PIRSF PIRSF017082 1 320 2.1E-84 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06175 a3947b783c375aa13e289dd9bfdbc347 320 SUPERFAMILY SSF53850 108 280 4.34E-12 T 06-07-2017 CAL12_RS06175 a3947b783c375aa13e289dd9bfdbc347 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 315 2.6E-85 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS23075 dcec37fb9b02f4f1040dcaad1f7845d2 441 Pfam PF01936 NYN domain 10 153 4.8E-32 T 06-07-2017 IPR021139 NYN domain, limkain-b1-type CAL12_RS23075 dcec37fb9b02f4f1040dcaad1f7845d2 441 Gene3D G3DSA:3.40.50.1010 2 156 3.1E-42 T 06-07-2017 IPR029060 PIN domain-like CAL12_RS02645 e5e8829f531c10e60fe59131b1d249ac 296 Pfam PF02535 ZIP Zinc transporter 144 291 3.5E-18 T 06-07-2017 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 SUPERFAMILY SSF103473 233 432 1.26E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 SUPERFAMILY SSF103473 18 202 1.26E-32 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 229 426 3.3E-34 T 06-07-2017 IPR010645 Uncharacterised MFS-type transporter YbfB CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 30 202 1.4E-43 T 06-07-2017 IPR010645 Uncharacterised MFS-type transporter YbfB CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 Gene3D G3DSA:1.20.1250.20 19 196 7.1E-16 T 06-07-2017 CAL12_RS16410 db96929d45126ed903449e2b492eb000 433 Gene3D G3DSA:1.20.1250.20 255 425 5.5E-6 T 06-07-2017 CAL12_RS20965 86d37eff3db46d8b933646db67b77bd6 385 Pfam PF00999 Sodium/hydrogen exchanger family 4 367 2.8E-58 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS06530 f3107de3e86505cdd499f473f77882ea 442 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 26 430 1.1E-105 T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CAL12_RS06530 f3107de3e86505cdd499f473f77882ea 442 Pfam PF00860 Permease family 31 408 4.3E-89 T 06-07-2017 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS06530 f3107de3e86505cdd499f473f77882ea 442 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 06-07-2017 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CAL12_RS09140 123c22bc545a609b44cb3da77b52d7dc 524 Pfam PF00263 Bacterial type II and III secretion system protein 355 519 3.0E-5 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAL12_RS12050 3848abd09a2806026cf59352c1f452f3 482 Pfam PF02120 Flagellar hook-length control protein FliK 405 476 1.3E-11 T 06-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal CAL12_RS20230 ef28721dcefedc7bdb55e12fb3368ede 805 Pfam PF04471 Restriction endonuclease 688 801 1.8E-19 T 06-07-2017 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CAL12_RS20230 ef28721dcefedc7bdb55e12fb3368ede 805 SUPERFAMILY SSF52980 688 803 3.49E-19 T 06-07-2017 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CAL12_RS20230 ef28721dcefedc7bdb55e12fb3368ede 805 Gene3D G3DSA:3.40.1350.10 687 801 7.3E-19 T 06-07-2017 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 SUPERFAMILY SSF89963 89 160 1.22E-28 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.0E-61 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 Gene3D G3DSA:3.30.70.860 94 160 1.1E-32 T 06-07-2017 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 SUPERFAMILY SSF89963 2 83 2.59E-28 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.583 T 06-07-2017 IPR007551 Protein of unknown function DUF520 CAL12_RS01625 fbd61f58c339b61a20370d5d2ec59d53 160 Gene3D G3DSA:3.30.70.990 9 93 3.0E-28 T 06-07-2017 CAL12_RS01835 07dc50fd6f43f744167db8962c9ecba7 775 Gene3D G3DSA:1.20.58.360 505 643 5.0E-18 T 06-07-2017 CAL12_RS01835 07dc50fd6f43f744167db8962c9ecba7 775 Pfam PF14496 C-terminal novel E3 ligase, LRR-interacting 437 647 2.6E-22 T 06-07-2017 IPR029487 Novel E3 ligase domain GO:0004842|GO:0016567 CAL12_RS01835 07dc50fd6f43f744167db8962c9ecba7 775 Gene3D G3DSA:3.80.10.10 271 346 1.2E-6 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS27035 ee450a2d519ba26f7d8271655d0fb618 293 SUPERFAMILY SSF103481 39 139 1.96E-15 T 06-07-2017 CAL12_RS27035 ee450a2d519ba26f7d8271655d0fb618 293 Pfam PF00892 EamA-like transporter family 9 136 1.6E-18 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS27035 ee450a2d519ba26f7d8271655d0fb618 293 Pfam PF00892 EamA-like transporter family 150 281 4.5E-19 T 06-07-2017 IPR000620 EamA domain GO:0016020|GO:0016021 CAL12_RS27035 ee450a2d519ba26f7d8271655d0fb618 293 SUPERFAMILY SSF103481 185 281 1.12E-14 T 06-07-2017 CAL12_RS04590 cac338cddfa7f3989f52f683ce577281 123 SUPERFAMILY SSF54909 1 116 4.29E-26 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS04590 cac338cddfa7f3989f52f683ce577281 123 Pfam PF03795 YCII-related domain 1 106 1.1E-15 T 06-07-2017 IPR005545 YCII-related CAL12_RS04590 cac338cddfa7f3989f52f683ce577281 123 Gene3D G3DSA:3.30.70.1060 1 117 2.1E-29 T 06-07-2017 CAL12_RS11375 b48dcae7f5b4208451cc54ea6d98c7f5 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 4.1E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS23570 f07b071aefb9b381d161adf2126966d0 261 Pfam PF13531 Bacterial extracellular solute-binding protein 29 254 9.5E-34 T 06-07-2017 CAL12_RS23570 f07b071aefb9b381d161adf2126966d0 261 SUPERFAMILY SSF53850 28 257 1.01E-38 T 06-07-2017 CAL12_RS23570 f07b071aefb9b381d161adf2126966d0 261 Gene3D G3DSA:3.40.190.10 27 164 3.5E-10 T 06-07-2017 CAL12_RS02090 307eb6af0f04dc6e48c13c108873db46 2116 SUPERFAMILY SSF103515 1837 2116 1.44E-33 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS02090 307eb6af0f04dc6e48c13c108873db46 2116 SMART SM00869 1841 2106 2.1E-16 T 06-07-2017 IPR005546 Autotransporter beta-domain CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 25 48 2.9E-9 T 06-07-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 106 128 2.9E-9 T 06-07-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 50 69 2.9E-9 T 06-07-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 PRINTS PR01595 Gram-negative bacterial type III secretion SycD chaperone signature 74 96 2.9E-9 T 06-07-2017 IPR005415 Type III secretion system, low calcium response, chaperone LcrH/SycD GO:0006950 CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 Gene3D G3DSA:1.25.40.10 39 136 3.8E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS22115 c2f8c037ef1aca7d38a4f4a2a215a522 160 SUPERFAMILY SSF48452 39 141 1.94E-11 T 06-07-2017 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CAL12_RS16735 87b23100c9ec8fffeff64e9204d10337 377 Pfam PF01757 Acyltransferase family 10 355 9.7E-29 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAL12_RS16095 8e105074b97f985a22b83c6a275bd66d 293 Pfam PF01522 Polysaccharide deacetylase 39 151 1.5E-19 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS16095 8e105074b97f985a22b83c6a275bd66d 293 Gene3D G3DSA:3.20.20.370 3 260 4.0E-58 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS16095 8e105074b97f985a22b83c6a275bd66d 293 SUPERFAMILY SSF88713 4 261 3.21E-48 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS04830 9b52a3733df6ba9e28bd8ce0509b7d0d 165 PIRSF PIRSF005859 3 161 6.1E-44 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAL12_RS04830 9b52a3733df6ba9e28bd8ce0509b7d0d 165 Pfam PF03073 TspO/MBR family 17 157 5.2E-38 T 06-07-2017 IPR004307 TspO/MBR-related protein GO:0016021 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 SMART SM01374 1 125 3.2E-73 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 SUPERFAMILY SSF50193 1 125 1.1E-44 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 125 2.7E-52 T 06-07-2017 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 Gene3D G3DSA:2.40.150.20 1 125 1.2E-48 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 125 24.841 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAL12_RS27575 6dd5a4b6e8995c5cdb4bb750bfbf0170 125 Pfam PF00238 Ribosomal protein L14p/L23e 1 125 6.7E-49 T 06-07-2017 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CAL12_RS19235 eff80899337babc0a150d4342714240d 150 Pfam PF09980 Predicted membrane protein (DUF2214) 4 149 6.3E-52 T 06-07-2017 IPR018706 Protein of unknown function DUF2214, membrane CAL12_RS18700 e053b16852a371f34cb928f032b1c3e5 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 24 202 1.7E-54 T 06-07-2017 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 CAL12_RS18700 e053b16852a371f34cb928f032b1c3e5 416 Pfam PF01435 Peptidase family M48 206 411 5.4E-36 T 06-07-2017 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CAL12_RS18700 e053b16852a371f34cb928f032b1c3e5 416 Gene3D G3DSA:3.30.2010.10 199 290 9.9E-20 T 06-07-2017 CAL12_RS26425 776a782a64c5c33bf1556d4dacbb07cf 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 1.2E-28 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS00155 feec270a30f649b978e7f0261f9e5f2f 255 SUPERFAMILY SSF55961 1 148 1.43E-28 T 06-07-2017 CAL12_RS00155 feec270a30f649b978e7f0261f9e5f2f 255 Gene3D G3DSA:3.30.530.20 1 155 4.3E-36 T 06-07-2017 IPR023393 START-like domain CAL12_RS00155 feec270a30f649b978e7f0261f9e5f2f 255 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 149 9.5E-16 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS01945 dadb3ad9a0b635b0dd1ffeb44756b909 343 SUPERFAMILY SSF53850 127 303 6.39E-13 T 06-07-2017 CAL12_RS01945 dadb3ad9a0b635b0dd1ffeb44756b909 343 Gene3D G3DSA:3.40.190.10 144 266 9.6E-6 T 06-07-2017 CAL12_RS01945 dadb3ad9a0b635b0dd1ffeb44756b909 343 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 65 339 1.5E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS01945 dadb3ad9a0b635b0dd1ffeb44756b909 343 PIRSF PIRSF017082 15 342 2.3E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10590 d65aba29991f80bbcff6fbbd287bdbad 357 Pfam PF09084 NMT1/THI5 like 45 259 1.4E-14 T 06-07-2017 IPR015168 SsuA/THI5-like CAL12_RS10590 d65aba29991f80bbcff6fbbd287bdbad 357 SUPERFAMILY SSF53850 46 269 4.04E-27 T 06-07-2017 CAL12_RS10590 d65aba29991f80bbcff6fbbd287bdbad 357 Gene3D G3DSA:3.40.190.10 118 231 1.1E-15 T 06-07-2017 CAL12_RS12085 bdad99de7e21cdf943ce1a7211ca6535 162 Pfam PF02674 Colicin V production protein 4 142 1.3E-35 T 06-07-2017 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CAL12_RS01535 fc7c44e3f7a8463f4d581a2df09cfa9c 299 Gene3D G3DSA:3.20.20.370 12 295 5.9E-64 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS01535 fc7c44e3f7a8463f4d581a2df09cfa9c 299 SUPERFAMILY SSF88713 13 295 3.89E-52 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS01535 fc7c44e3f7a8463f4d581a2df09cfa9c 299 Pfam PF01522 Polysaccharide deacetylase 76 181 7.6E-6 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS23200 8461e40c096179a3323a4f8d13c962cd 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 299 8.9E-41 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS13325 046fa181abb3741def5753dd647900e0 465 Gene3D G3DSA:3.30.1330.120 282 378 6.2E-9 T 06-07-2017 CAL12_RS13325 046fa181abb3741def5753dd647900e0 465 SUPERFAMILY SSF103378 23 452 3.27E-91 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS13325 046fa181abb3741def5753dd647900e0 465 Pfam PF03972 MmgE/PrpD family 26 440 4.6E-91 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 Pfam PF12951 Passenger-associated-transport-repeat 71 99 3.5E-6 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 Pfam PF12951 Passenger-associated-transport-repeat 8 34 1.6E-9 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 70 99 9.1E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 7 34 9.1E-12 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 Gene3D G3DSA:2.160.20.20 1 39 1.6E-4 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 Gene3D G3DSA:2.160.20.20 42 98 9.7E-6 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23625 cf129d2fc209afab88aaf3c17f51814c 99 SUPERFAMILY SSF51126 1 98 6.28E-12 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS18880 26e9ccb9a56b8ef9d589c3adad640211 463 Pfam PF13406 Transglycosylase SLT domain 93 405 1.2E-83 T 06-07-2017 IPR031304 Transglycosylase SLT domain 2 CAL12_RS18880 26e9ccb9a56b8ef9d589c3adad640211 463 SUPERFAMILY SSF53955 83 410 6.05E-74 T 06-07-2017 IPR023346 Lysozyme-like domain CAL12_RS18880 26e9ccb9a56b8ef9d589c3adad640211 463 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 97 408 2.4E-105 T 06-07-2017 IPR011757 Lytic transglycosylase MltB CAL12_RS18880 26e9ccb9a56b8ef9d589c3adad640211 463 Gene3D G3DSA:1.10.530.10 281 412 1.2E-44 T 06-07-2017 CAL12_RS18880 26e9ccb9a56b8ef9d589c3adad640211 463 Gene3D G3DSA:1.10.530.10 140 195 1.2E-44 T 06-07-2017 CAL12_RS00305 0324eb74c4df0c4fa2e0612144037756 152 Pfam PF03500 Cellulose synthase subunit D 37 130 5.6E-6 T 06-07-2017 IPR022798 Cellulose synthase subunit D, bacterial CAL12_RS00530 01da94581611aed7bfa3f27af58c9438 535 Gene3D G3DSA:3.90.226.10 280 530 9.7E-94 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS00530 01da94581611aed7bfa3f27af58c9438 535 Gene3D G3DSA:3.90.226.10 28 270 1.9E-80 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS00530 01da94581611aed7bfa3f27af58c9438 535 Pfam PF01039 Carboxyl transferase domain 48 525 6.8E-151 T 06-07-2017 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CAL12_RS00530 01da94581611aed7bfa3f27af58c9438 535 SUPERFAMILY SSF52096 25 272 3.19E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS00530 01da94581611aed7bfa3f27af58c9438 535 SUPERFAMILY SSF52096 237 517 5.88E-87 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS07895 6e69fa6afbd6e2955bad65570bbc1195 460 Gene3D G3DSA:1.20.1250.20 24 222 3.2E-19 T 06-07-2017 CAL12_RS07895 6e69fa6afbd6e2955bad65570bbc1195 460 Gene3D G3DSA:1.20.1250.20 269 456 2.4E-11 T 06-07-2017 CAL12_RS07895 6e69fa6afbd6e2955bad65570bbc1195 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS07895 6e69fa6afbd6e2955bad65570bbc1195 460 Pfam PF07690 Major Facilitator Superfamily 29 410 2.1E-23 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS07895 6e69fa6afbd6e2955bad65570bbc1195 460 SUPERFAMILY SSF103473 19 457 1.02E-49 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05270 c0a8b31c18b344a83085f20937d88ade 269 Gene3D G3DSA:3.40.50.1820 22 267 3.6E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05270 c0a8b31c18b344a83085f20937d88ade 269 SUPERFAMILY SSF53474 21 267 3.38E-45 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS05270 c0a8b31c18b344a83085f20937d88ade 269 Pfam PF12697 Alpha/beta hydrolase family 37 261 3.8E-18 T 06-07-2017 IPR000073 Alpha/beta hydrolase fold-1 CAL12_RS10720 390227fefd15377d6f4a2d9448efecca 334 PIRSF PIRSF017082 4 332 7.8E-72 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10720 390227fefd15377d6f4a2d9448efecca 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 328 3.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS10720 390227fefd15377d6f4a2d9448efecca 334 SUPERFAMILY SSF53850 125 285 8.68E-9 T 06-07-2017 CAL12_RS20160 40781255d65f37166e7f4660321bd400 570 Pfam PF00263 Bacterial type II and III secretion system protein 407 535 4.5E-7 T 06-07-2017 IPR004846 Type II/III secretion system GO:0009306 CAL12_RS09845 0a850f512c8030876ffc060822f048ed 520 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 499 7.4E-171 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAL12_RS01810 55d36f2945cf1d12f187a439565470c8 113 Pfam PF07883 Cupin domain 30 84 6.2E-11 T 06-07-2017 IPR013096 Cupin 2, conserved barrel CAL12_RS01810 55d36f2945cf1d12f187a439565470c8 113 SUPERFAMILY SSF51182 30 97 1.02E-15 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS01810 55d36f2945cf1d12f187a439565470c8 113 Gene3D G3DSA:2.60.120.10 27 95 1.5E-13 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 SUPERFAMILY SSF56235 11 498 4.82E-113 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 221 237 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 380 395 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 38 63 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 349 367 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 325 343 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 421 2.6E-31 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 Pfam PF01019 Gamma-glutamyltranspeptidase 33 269 1.8E-58 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS14755 f614af5c4e7afac2908ce2f5a7ae919c 505 Pfam PF01019 Gamma-glutamyltranspeptidase 318 499 7.5E-36 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS09270 bb97f65d201f1578178c2fbf7555e943 385 Gene3D G3DSA:3.30.930.10 17 316 2.5E-56 T 06-07-2017 CAL12_RS09270 bb97f65d201f1578178c2fbf7555e943 385 Pfam PF13393 Histidyl-tRNA synthetase 10 316 1.6E-108 T 06-07-2017 CAL12_RS09270 bb97f65d201f1578178c2fbf7555e943 385 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 367 33.276 T 06-07-2017 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CAL12_RS09270 bb97f65d201f1578178c2fbf7555e943 385 PIRSF PIRSF001549 6 356 3.1E-33 T 06-07-2017 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CAL12_RS09270 bb97f65d201f1578178c2fbf7555e943 385 SUPERFAMILY SSF55681 4 319 7.11E-51 T 06-07-2017 CAL12_RS11195 dce5a915bd5c9b1b4b8c3ff13b2af026 326 SUPERFAMILY SSF53850 112 281 6.91E-16 T 06-07-2017 CAL12_RS11195 dce5a915bd5c9b1b4b8c3ff13b2af026 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 310 3.1E-59 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11195 dce5a915bd5c9b1b4b8c3ff13b2af026 326 PIRSF PIRSF017082 1 321 1.2E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11195 dce5a915bd5c9b1b4b8c3ff13b2af026 326 Gene3D G3DSA:3.40.190.10 125 219 3.0E-6 T 06-07-2017 CAL12_RS05570 7dd4735f1e6d5aa177a6a1aa3c4dedca 321 SUPERFAMILY SSF53686 7 314 1.2E-91 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS05570 7dd4735f1e6d5aa177a6a1aa3c4dedca 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 307 3.8E-72 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS05570 7dd4735f1e6d5aa177a6a1aa3c4dedca 321 Gene3D G3DSA:3.40.50.1100 74 316 3.8E-66 T 06-07-2017 CAL12_RS06705 350f3fb1777ffac016f90648ca03c996 100 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 93 7.2E-10 T 06-07-2017 IPR009799 EthD domain CAL12_RS06705 350f3fb1777ffac016f90648ca03c996 100 Gene3D G3DSA:3.30.70.900 3 93 2.6E-14 T 06-07-2017 CAL12_RS06705 350f3fb1777ffac016f90648ca03c996 100 SUPERFAMILY SSF54909 1 93 1.74E-12 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS03870 2638614703ff7e117a5cc0765088be72 323 PIRSF PIRSF017082 1 323 6.8E-80 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS03870 2638614703ff7e117a5cc0765088be72 323 SUPERFAMILY SSF53850 110 286 1.26E-14 T 06-07-2017 CAL12_RS03870 2638614703ff7e117a5cc0765088be72 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 6.8E-81 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS11320 82f1ab48c9227d6a6a8e74ace7738d6f 138 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 40 138 2.1E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS10195 198afd4a1228f7360a02cacc3c9b7684 91 SUPERFAMILY SSF47336 2 81 4.32E-16 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS10195 198afd4a1228f7360a02cacc3c9b7684 91 Gene3D G3DSA:1.10.1200.10 2 80 5.3E-15 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS10195 198afd4a1228f7360a02cacc3c9b7684 91 Pfam PF00550 Phosphopantetheine attachment site 10 76 2.2E-10 T 06-07-2017 IPR009081 Phosphopantetheine binding ACP domain CAL12_RS21645 21edb15e4ee09978b95e5db54eb3b197 474 Pfam PF01425 Amidase 27 450 7.9E-129 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS21645 21edb15e4ee09978b95e5db54eb3b197 474 SUPERFAMILY SSF75304 4 466 7.33E-153 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS21645 21edb15e4ee09978b95e5db54eb3b197 474 Gene3D G3DSA:3.90.1300.10 3 468 2.4E-165 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS24505 e8c53d8fa1f6f0cd4aaa30ad74bf4364 428 SUPERFAMILY SSF51556 61 350 2.73E-61 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS24505 e8c53d8fa1f6f0cd4aaa30ad74bf4364 428 Gene3D G3DSA:2.30.40.10 12 70 7.5E-6 T 06-07-2017 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CAL12_RS24505 e8c53d8fa1f6f0cd4aaa30ad74bf4364 428 Pfam PF07969 Amidohydrolase family 165 336 4.2E-12 T 06-07-2017 IPR013108 Amidohydrolase 3 CAL12_RS24505 e8c53d8fa1f6f0cd4aaa30ad74bf4364 428 Gene3D G3DSA:3.20.20.140 71 351 7.2E-68 T 06-07-2017 CAL12_RS11535 e9b7e195caa48331a806b3755411d2df 103 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 6 100 6.0E-24 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS21215 75cda6175af47cac4ae5a5c1b941946b 472 SUPERFAMILY SSF52467 294 468 1.68E-69 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS21215 75cda6175af47cac4ae5a5c1b941946b 472 Pfam PF02233 NAD(P) transhydrogenase beta subunit 12 464 4.9E-164 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS21215 75cda6175af47cac4ae5a5c1b941946b 472 PIRSF PIRSF000204 4 468 3.8E-149 T 06-07-2017 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS21215 75cda6175af47cac4ae5a5c1b941946b 472 Gene3D G3DSA:3.40.50.1220 290 468 2.1E-81 T 06-07-2017 IPR029035 DHS-like NAD/FAD-binding domain CAL12_RS01200 f53772c7bffc7465c661ecb4a833ad84 381 SUPERFAMILY SSF51419 16 239 7.2E-41 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS01200 f53772c7bffc7465c661ecb4a833ad84 381 Pfam PF14031 Putative serine dehydratase domain 256 364 2.7E-18 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS01200 f53772c7bffc7465c661ecb4a833ad84 381 SMART SM01119 256 367 4.4E-36 T 06-07-2017 IPR026956 D-serine dehydratase-like domain CAL12_RS01200 f53772c7bffc7465c661ecb4a833ad84 381 Gene3D G3DSA:3.20.20.10 22 237 4.3E-27 T 06-07-2017 IPR029066 PLP-binding barrel CAL12_RS01200 f53772c7bffc7465c661ecb4a833ad84 381 Pfam PF01168 Alanine racemase, N-terminal domain 15 241 2.5E-37 T 06-07-2017 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CAL12_RS23785 f1cfc9a71dad1cf8b6956fd58920e185 320 Gene3D G3DSA:3.40.50.1100 71 315 1.4E-69 T 06-07-2017 CAL12_RS23785 f1cfc9a71dad1cf8b6956fd58920e185 320 SUPERFAMILY SSF53686 8 312 1.83E-87 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS23785 f1cfc9a71dad1cf8b6956fd58920e185 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 307 1.6E-77 T 06-07-2017 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CAL12_RS07330 32bf924fc4cff076de71ef37ac1fa22d 192 SUPERFAMILY SSF46626 54 184 2.82E-20 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS07330 32bf924fc4cff076de71ef37ac1fa22d 192 Gene3D G3DSA:1.10.760.10 58 159 1.1E-17 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS07330 32bf924fc4cff076de71ef37ac1fa22d 192 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 73 154 2.0E-9 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS15845 d22729a20ee406ef95df061a79e2cb4a 350 SUPERFAMILY SSF53850 139 311 2.42E-19 T 06-07-2017 CAL12_RS15845 d22729a20ee406ef95df061a79e2cb4a 350 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 74 347 9.8E-96 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15845 d22729a20ee406ef95df061a79e2cb4a 350 PIRSF PIRSF017082 17 350 5.2E-88 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS15845 d22729a20ee406ef95df061a79e2cb4a 350 Gene3D G3DSA:3.40.190.10 154 253 6.6E-6 T 06-07-2017 CAL12_RS10820 a55adf38246cf896eacee044157ecb98 485 SUPERFAMILY SSF103378 1 451 1.01E-91 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS10820 a55adf38246cf896eacee044157ecb98 485 Gene3D G3DSA:3.30.1330.120 268 400 8.8E-20 T 06-07-2017 CAL12_RS10820 a55adf38246cf896eacee044157ecb98 485 Pfam PF03972 MmgE/PrpD family 1 437 2.2E-94 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS14665 52453de5ad52569d7ddc6893e0f248e5 230 Gene3D G3DSA:3.40.190.10 3 70 1.7E-9 T 06-07-2017 CAL12_RS14665 52453de5ad52569d7ddc6893e0f248e5 230 Gene3D G3DSA:3.40.190.10 71 163 5.6E-14 T 06-07-2017 CAL12_RS14665 52453de5ad52569d7ddc6893e0f248e5 230 Pfam PF03466 LysR substrate binding domain 7 192 1.1E-34 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS14665 52453de5ad52569d7ddc6893e0f248e5 230 SUPERFAMILY SSF53850 4 192 9.29E-31 T 06-07-2017 CAL12_RS10025 aa1e9c8a56a34a7bdf54ba8dd108db26 262 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 24 205 9.9E-45 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS10025 aa1e9c8a56a34a7bdf54ba8dd108db26 262 SUPERFAMILY SSF53639 17 222 2.35E-59 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS10025 aa1e9c8a56a34a7bdf54ba8dd108db26 262 Gene3D G3DSA:3.40.225.10 18 223 1.5E-60 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS10025 aa1e9c8a56a34a7bdf54ba8dd108db26 262 SMART SM01007 23 205 7.0E-61 T 06-07-2017 IPR001303 Class II aldolase/adducin N-terminal CAL12_RS07240 bbdf2130e80954ef5bfdb49814310636 313 Gene3D G3DSA:3.20.20.70 6 307 7.7E-108 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS07240 bbdf2130e80954ef5bfdb49814310636 313 Pfam PF05853 beta-keto acid cleavage enzyme 7 305 9.3E-104 T 06-07-2017 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24 CAL12_RS13345 0dfdd26ed533be12ee924dbcf69863be 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 278 4.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS19330 e530a88b23938f2277c8d801470806aa 233 Gene3D G3DSA:3.40.50.150 5 192 1.3E-18 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19330 e530a88b23938f2277c8d801470806aa 233 Pfam PF13489 Methyltransferase domain 13 127 3.5E-11 T 06-07-2017 CAL12_RS19330 e530a88b23938f2277c8d801470806aa 233 SUPERFAMILY SSF53335 3 189 5.89E-22 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02470 ca842107b219ac65c306c69f36ffe57e 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 294 1.0E-27 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02470 ca842107b219ac65c306c69f36ffe57e 304 Gene3D G3DSA:1.10.3720.10 100 294 6.4E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02470 ca842107b219ac65c306c69f36ffe57e 304 SUPERFAMILY SSF161098 101 282 1.14E-33 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS05705 fef19993d645e48e3217d27e8172ec65 278 Pfam PF03591 AzlC protein 62 206 1.3E-32 T 06-07-2017 IPR011606 Branched-chain amino acid transport, permease CAL12_RS24675 7877b91da7e1595b144e39f32d6947ed 511 Pfam PF04293 SpoVR like protein 25 454 1.3E-170 T 06-07-2017 IPR007390 Sporulation stage V, protein R CAL12_RS02095 e947ce6a6b75a3398a7ec2a28c3899b7 381 Gene3D G3DSA:3.40.190.10 185 281 4.2E-6 T 06-07-2017 CAL12_RS02095 e947ce6a6b75a3398a7ec2a28c3899b7 381 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 105 374 7.8E-64 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02095 e947ce6a6b75a3398a7ec2a28c3899b7 381 SUPERFAMILY SSF53850 172 344 4.68E-14 T 06-07-2017 CAL12_RS08200 68731b9edf85de842a89d40e5df41893 237 SMART SM00382 30 197 9.8E-9 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS08200 68731b9edf85de842a89d40e5df41893 237 SUPERFAMILY SSF52540 4 229 4.05E-53 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08200 68731b9edf85de842a89d40e5df41893 237 Pfam PF00005 ABC transporter 21 164 1.0E-21 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS08200 68731b9edf85de842a89d40e5df41893 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS08200 68731b9edf85de842a89d40e5df41893 237 Gene3D G3DSA:3.40.50.300 3 229 4.2E-51 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 SUPERFAMILY SSF56235 3 177 1.02E-60 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 Pfam PF00227 Proteasome subunit 5 174 2.3E-24 T 06-07-2017 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5687128|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-983168 CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 2.3E-85 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.63 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 PIRSF PIRSF039093 1 179 2.6E-86 T 06-07-2017 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 CAL12_RS26740 3af9dc343b28a6c50260ac41030268b6 179 Gene3D G3DSA:3.60.20.10 7 177 5.4E-85 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS05140 8f38443b068a916dc034a20f3aee8344 158 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 15 157 2.8E-49 T 06-07-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAL12_RS05140 8f38443b068a916dc034a20f3aee8344 158 Pfam PF06754 Phosphonate metabolism protein PhnG 15 156 6.2E-50 T 06-07-2017 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399 CAL12_RS11160 f3d4d72cc82d2bce8f2d17a1da08cfaa 397 Gene3D G3DSA:3.40.50.1820 138 386 4.6E-43 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11160 f3d4d72cc82d2bce8f2d17a1da08cfaa 397 Gene3D G3DSA:1.20.1440.110 25 134 2.1E-29 T 06-07-2017 CAL12_RS11160 f3d4d72cc82d2bce8f2d17a1da08cfaa 397 SUPERFAMILY SSF53474 25 390 2.82E-62 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11160 f3d4d72cc82d2bce8f2d17a1da08cfaa 397 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 86 269 1.8E-9 T 06-07-2017 IPR010520 UPF0255 family CAL12_RS11260 aab9e4d66b259491932c5981bbf8a430 547 Pfam PF02538 Hydantoinase B/oxoprolinase 18 526 2.6E-138 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS11590 bad69a3d855ddc1c5ee58995a58eb967 315 SUPERFAMILY SSF161098 90 297 5.36E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11590 bad69a3d855ddc1c5ee58995a58eb967 315 Gene3D G3DSA:1.10.3720.10 89 309 6.2E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11590 bad69a3d855ddc1c5ee58995a58eb967 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 2.1E-43 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS19145 a6365219bac98983087cf25a7cac267c 290 Pfam PF03239 Iron permease FTR1 family 4 263 2.6E-22 T 06-07-2017 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CAL12_RS03425 f6c05b5a7b201b468bb45574ff2f243d 536 Pfam PF01425 Amidase 60 517 1.3E-86 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS03425 f6c05b5a7b201b468bb45574ff2f243d 536 Gene3D G3DSA:3.90.1300.10 36 531 3.6E-121 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS03425 f6c05b5a7b201b468bb45574ff2f243d 536 SUPERFAMILY SSF75304 25 525 7.33E-106 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS03830 9c35b7ef37b7b785b84ea5c9988cb1fd 211 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 1.2E-24 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS12060 22bbb9a889f9ecb1e537d0e015fde0af 142 Gene3D G3DSA:1.20.120.340 16 132 4.5E-32 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 CAL12_RS12060 22bbb9a889f9ecb1e537d0e015fde0af 142 TIGRFAM TIGR00208 fliS: flagellar protein FliS 15 133 6.3E-24 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 CAL12_RS12060 22bbb9a889f9ecb1e537d0e015fde0af 142 SUPERFAMILY SSF101116 16 132 8.24E-29 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 CAL12_RS12060 22bbb9a889f9ecb1e537d0e015fde0af 142 Pfam PF02561 Flagellar protein FliS 23 131 3.2E-29 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 CAL12_RS12060 22bbb9a889f9ecb1e537d0e015fde0af 142 PIRSF PIRSF039090 9 142 3.0E-31 T 06-07-2017 IPR003713 Flagellar protein FliS GO:0044780 CAL12_RS01030 492143d3b664d28ca8b298123cedf052 297 Pfam PF01040 UbiA prenyltransferase family 27 273 4.2E-58 T 06-07-2017 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 CAL12_RS01030 492143d3b664d28ca8b298123cedf052 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 292 19.169 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAL12_RS01030 492143d3b664d28ca8b298123cedf052 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 291 7.9E-92 T 06-07-2017 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CAL12_RS06755 68d13b5fcd38f40c7ebef294323283a1 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 319 5.5E-52 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06755 68d13b5fcd38f40c7ebef294323283a1 326 PIRSF PIRSF017082 1 325 1.0E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06755 68d13b5fcd38f40c7ebef294323283a1 326 SUPERFAMILY SSF53850 35 279 4.53E-11 T 06-07-2017 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 7 249 18.777 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 Pfam PF00902 Sec-independent protein translocase protein (TatC) 19 230 1.7E-65 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 112 138 1.3E-47 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 163 191 1.3E-47 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 94 112 1.3E-47 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 1.3E-47 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS00785 a24f7217c75e670912aaee894879bdf9 271 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 17 235 2.3E-67 T 06-07-2017 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CAL12_RS05915 5f6dba63bb445b86497246dd33449830 57 SUPERFAMILY SSF64288 2 56 2.83E-11 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS05915 5f6dba63bb445b86497246dd33449830 57 Pfam PF07702 UTRA domain 2 47 2.8E-8 T 06-07-2017 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CAL12_RS05915 5f6dba63bb445b86497246dd33449830 57 Gene3D G3DSA:3.40.1410.10 3 54 2.8E-10 T 06-07-2017 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CAL12_RS22680 6648b26e470c3dd5a2ed770af6e9cb1c 247 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 86 220 5.1E-36 T 06-07-2017 IPR017734 Type VI secretion system, lipoprotein SciN CAL12_RS22680 6648b26e470c3dd5a2ed770af6e9cb1c 247 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 92 219 2.4E-36 T 06-07-2017 IPR017734 Type VI secretion system, lipoprotein SciN CAL12_RS18260 cbc1957b6a8d2d90d6f0a3a0c53260c3 477 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 35 214 1.8E-54 T 06-07-2017 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 CAL12_RS22715 fd933cf162be7b337d693ea503fd2773 192 SUPERFAMILY SSF141452 44 190 8.89E-17 T 06-07-2017 IPR008514 Type VI secretion system effector, Hcp CAL12_RS22715 fd933cf162be7b337d693ea503fd2773 192 Pfam PF05638 Type VI secretion system effector, Hcp 44 165 9.3E-10 T 06-07-2017 IPR008514 Type VI secretion system effector, Hcp CAL12_RS22715 fd933cf162be7b337d693ea503fd2773 192 Gene3D G3DSA:2.30.110.20 44 189 3.3E-13 T 06-07-2017 IPR008514 Type VI secretion system effector, Hcp CAL12_RS02035 7d1d34620abfa7f07f7889149aaa2b6d 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 249 1.1E-18 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02035 7d1d34620abfa7f07f7889149aaa2b6d 254 SUPERFAMILY SSF161098 58 238 4.45E-24 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS02035 7d1d34620abfa7f07f7889149aaa2b6d 254 Gene3D G3DSA:1.10.3720.10 56 250 9.0E-15 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS10600 59f42b432804d4bef2b47637d66fb727 202 Pfam PF02311 AraC-like ligand binding domain 87 174 1.2E-4 T 06-07-2017 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CAL12_RS10600 59f42b432804d4bef2b47637d66fb727 202 Gene3D G3DSA:2.60.120.10 63 193 3.5E-26 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS10600 59f42b432804d4bef2b47637d66fb727 202 SUPERFAMILY SSF51182 11 192 4.19E-37 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS09595 bd5e3918c971c0bab66b4741de0af362 292 Pfam PF00482 Type II secretion system (T2SS), protein F 158 279 2.7E-16 T 06-07-2017 IPR018076 Type II secretion system F domain CAL12_RS20005 4036995beb661c0adf70b3f9fbc371b1 313 Pfam PF00487 Fatty acid desaturase 65 291 2.0E-21 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAL12_RS20005 4036995beb661c0adf70b3f9fbc371b1 313 PRINTS PR00075 Fatty acid desaturase family 1 signature 258 272 1.7E-6 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAL12_RS20005 4036995beb661c0adf70b3f9fbc371b1 313 PRINTS PR00075 Fatty acid desaturase family 1 signature 55 75 1.7E-6 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAL12_RS20005 4036995beb661c0adf70b3f9fbc371b1 313 PRINTS PR00075 Fatty acid desaturase family 1 signature 215 236 1.7E-6 T 06-07-2017 IPR015876 Fatty acid desaturase, type 1, core GO:0016717|GO:0055114 Reactome: R-HSA-75105 CAL12_RS06680 5908af87d5f83acf938dff0cb0bdbd5e 172 Pfam PF13924 Lipocalin-like domain 38 170 1.3E-29 T 06-07-2017 IPR024311 Lipocalin-like domain CAL12_RS14960 6e190aaf1cfce2d3e474623bc6b74fe7 324 Pfam PF05229 Spore Coat Protein U domain 20 149 1.4E-11 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS14960 6e190aaf1cfce2d3e474623bc6b74fe7 324 Pfam PF05229 Spore Coat Protein U domain 188 321 6.2E-36 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS14960 6e190aaf1cfce2d3e474623bc6b74fe7 324 SMART SM00972 262 321 1.0E-22 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS14960 6e190aaf1cfce2d3e474623bc6b74fe7 324 SMART SM00972 94 165 0.13 T 06-07-2017 IPR007893 Spore coat protein U CAL12_RS00875 88c33d95cfb7823c73eea39156511aec 282 Pfam PF04333 MlaA lipoprotein 31 225 1.4E-71 T 06-07-2017 IPR007428 MlaA lipoprotein GO:0016020 CAL12_RS00875 88c33d95cfb7823c73eea39156511aec 282 PRINTS PR01805 VacJ lipoprotein signature 32 45 3.3E-27 T 06-07-2017 IPR007428 MlaA lipoprotein GO:0016020 CAL12_RS00875 88c33d95cfb7823c73eea39156511aec 282 PRINTS PR01805 VacJ lipoprotein signature 49 65 3.3E-27 T 06-07-2017 IPR007428 MlaA lipoprotein GO:0016020 CAL12_RS00875 88c33d95cfb7823c73eea39156511aec 282 PRINTS PR01805 VacJ lipoprotein signature 136 153 3.3E-27 T 06-07-2017 IPR007428 MlaA lipoprotein GO:0016020 CAL12_RS00875 88c33d95cfb7823c73eea39156511aec 282 PRINTS PR01805 VacJ lipoprotein signature 100 117 3.3E-27 T 06-07-2017 IPR007428 MlaA lipoprotein GO:0016020 CAL12_RS16240 22a640ecdc415f0cec746c15db117a90 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 339 2.0E-89 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16240 22a640ecdc415f0cec746c15db117a90 342 PIRSF PIRSF017082 20 341 6.8E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16240 22a640ecdc415f0cec746c15db117a90 342 SUPERFAMILY SSF53850 131 303 9.17E-10 T 06-07-2017 CAL12_RS23700 6a136775712aa36e4e50b6c9c5e3e2c0 61 Gene3D G3DSA:2.160.20.20 5 60 1.8E-8 T 06-07-2017 IPR012332 P22 tailspike C-terminal domain-like CAL12_RS23700 6a136775712aa36e4e50b6c9c5e3e2c0 61 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 32 60 1.1E-8 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23700 6a136775712aa36e4e50b6c9c5e3e2c0 61 Pfam PF12951 Passenger-associated-transport-repeat 33 61 2.1E-7 T 06-07-2017 IPR013425 Autotransporter-associated beta strand repeat CAL12_RS23700 6a136775712aa36e4e50b6c9c5e3e2c0 61 SUPERFAMILY SSF51126 7 59 3.14E-6 T 06-07-2017 IPR011050 Pectin lyase fold/virulence factor CAL12_RS03915 ac0c3af9476e7943183f5aae6d147b86 140 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 9 138 6.1E-10 T 06-07-2017 IPR009936 Protein of unknown function DUF1468 CAL12_RS03465 12db311eddf2c424991aa879fb6661b7 119 Gene3D G3DSA:3.30.1330.40 6 117 4.8E-23 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS03465 12db311eddf2c424991aa879fb6661b7 119 Pfam PF01042 Endoribonuclease L-PSP 4 115 1.0E-21 T 06-07-2017 IPR006175 YjgF/YER057c/UK114 family CAL12_RS03465 12db311eddf2c424991aa879fb6661b7 119 SUPERFAMILY SSF55298 6 117 2.04E-28 T 06-07-2017 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CAL12_RS02150 0b8c008770353fc1d56561a790dcefd4 209 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 26 198 4.1E-24 T 06-07-2017 IPR003740 Uncharacterised membrane protein YitT CAL12_RS08520 5fa3673e4623033e4c6aacd1b68e24c8 202 Gene3D G3DSA:1.20.1440.20 22 202 3.4E-62 T 06-07-2017 IPR023353 LemA-like domain CAL12_RS08520 5fa3673e4623033e4c6aacd1b68e24c8 202 SUPERFAMILY SSF140478 32 189 9.29E-54 T 06-07-2017 IPR023353 LemA-like domain CAL12_RS08520 5fa3673e4623033e4c6aacd1b68e24c8 202 Pfam PF04011 LemA family 14 202 3.4E-65 T 06-07-2017 IPR007156 LemA CAL12_RS02325 0a2d6761a32b8bee663f5938c3bc0721 667 Gene3D G3DSA:2.120.10.30 64 307 4.1E-15 T 06-07-2017 IPR011042 Six-bladed beta-propeller, TolB-like CAL12_RS02325 0a2d6761a32b8bee663f5938c3bc0721 667 SUPERFAMILY SSF53474 404 659 2.63E-73 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02325 0a2d6761a32b8bee663f5938c3bc0721 667 Pfam PF00326 Prolyl oligopeptidase family 448 659 1.1E-49 T 06-07-2017 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CAL12_RS02325 0a2d6761a32b8bee663f5938c3bc0721 667 SUPERFAMILY SSF82171 65 396 4.32E-15 T 06-07-2017 CAL12_RS02325 0a2d6761a32b8bee663f5938c3bc0721 667 Gene3D G3DSA:3.40.50.1820 351 659 2.2E-94 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS19675 e55e27cf006996abeca4d049adc1ebec 357 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 352 24.928 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19675 e55e27cf006996abeca4d049adc1ebec 357 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 233 246 - T 06-07-2017 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS19675 e55e27cf006996abeca4d049adc1ebec 357 Pfam PF00146 NADH dehydrogenase 28 345 3.8E-125 T 06-07-2017 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CAL12_RS00210 b5c29b43559d991eaa155eb6bc8fa00a 191 Pfam PF13663 Domain of unknown function (DUF4148) 81 150 2.0E-7 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS00855 c70b3a262fde6db1a1325932bdcef24c 80 Gene3D G3DSA:3.30.300.90 2 79 7.4E-29 T 06-07-2017 IPR002634 BolA protein CAL12_RS00855 c70b3a262fde6db1a1325932bdcef24c 80 Pfam PF01722 BolA-like protein 20 75 2.3E-20 T 06-07-2017 IPR002634 BolA protein CAL12_RS00855 c70b3a262fde6db1a1325932bdcef24c 80 SUPERFAMILY SSF82657 1 78 2.35E-29 T 06-07-2017 IPR002634 BolA protein CAL12_RS00855 c70b3a262fde6db1a1325932bdcef24c 80 PIRSF PIRSF003113 1 80 2.8E-24 T 06-07-2017 IPR002634 BolA protein CAL12_RS15355 895bd09c67f7ba8a1496c81ab12d6889 209 Pfam PF03458 UPF0126 domain 95 165 3.2E-22 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 CAL12_RS15355 895bd09c67f7ba8a1496c81ab12d6889 209 Pfam PF03458 UPF0126 domain 9 82 6.6E-19 T 06-07-2017 IPR005115 Uncharacterised domain UPF0126 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 ProSitePatterns PS00216 Sugar transport proteins signature 1. 82 98 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 SUPERFAMILY SSF103473 20 426 4.19E-68 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 Pfam PF00083 Sugar (and other) transporter 25 229 5.0E-29 T 06-07-2017 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 06-07-2017 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 Gene3D G3DSA:1.20.1250.20 247 432 2.7E-23 T 06-07-2017 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 Gene3D G3DSA:1.20.1250.20 22 228 4.6E-25 T 06-07-2017 CAL12_RS07445 fed7f28934310154677498777d0dc2b2 436 Pfam PF07690 Major Facilitator Superfamily 251 431 1.9E-16 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS08450 139145b7672472e2c12ed3b48ce0b02e 150 SUPERFAMILY SSF102400 1 142 1.83E-32 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAL12_RS08450 139145b7672472e2c12ed3b48ce0b02e 150 Gene3D G3DSA:3.40.50.10110 1 143 3.7E-36 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAL12_RS08450 139145b7672472e2c12ed3b48ce0b02e 150 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 137 2.7E-34 T 06-07-2017 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 CAL12_RS27590 0661aef1fd597b38588c4c2e4d22484c 341 SUPERFAMILY SSF53850 128 300 8.32E-12 T 06-07-2017 CAL12_RS27590 0661aef1fd597b38588c4c2e4d22484c 341 PIRSF PIRSF017082 13 341 6.7E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27590 0661aef1fd597b38588c4c2e4d22484c 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 338 5.6E-93 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13860 8568b44f55c4c9d85773ebea93952c50 179 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 102 1.2E-9 T 06-07-2017 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS13860 8568b44f55c4c9d85773ebea93952c50 179 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 59 97 1.1E-7 T 06-07-2017 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CAL12_RS13860 8568b44f55c4c9d85773ebea93952c50 179 Gene3D G3DSA:1.20.1290.10 1 89 1.4E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS13860 8568b44f55c4c9d85773ebea93952c50 179 Gene3D G3DSA:1.20.1290.10 139 176 1.4E-26 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS13860 8568b44f55c4c9d85773ebea93952c50 179 SUPERFAMILY SSF69118 1 176 5.23E-41 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS07655 ada7ee103a76a857af0e2bb7a979b088 326 Pfam PF01522 Polysaccharide deacetylase 35 150 2.6E-5 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS07655 ada7ee103a76a857af0e2bb7a979b088 326 SUPERFAMILY SSF88713 39 164 2.78E-13 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS07655 ada7ee103a76a857af0e2bb7a979b088 326 Gene3D G3DSA:3.20.20.370 37 171 3.1E-10 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS02305 6be4a45e47827c05cf22e2989d582248 121 Pfam PF13663 Domain of unknown function (DUF4148) 15 82 1.5E-9 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS07460 602c84644f7aa73b6c365fdaa50dcd36 165 Pfam PF06496 Protein of unknown function (DUF1097) 14 147 7.9E-23 T 06-07-2017 IPR009476 Protein of unknown function DUF1097 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 SUPERFAMILY SSF56235 2 367 2.1E-142 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 SUPERFAMILY SSF56235 405 591 2.1E-142 T 06-07-2017 IPR029055 Nucleophile aminohydrolases, N-terminal CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 246 262 6.0E-21 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 410 428 6.0E-21 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 6.0E-21 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 6.0E-21 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 6.0E-21 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS19720 db3ec4c4a42fb57dab8f77a5369bab24 600 Pfam PF01019 Gamma-glutamyltranspeptidase 28 591 2.0E-122 T 06-07-2017 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CAL12_RS12000 0edc116a8db816f9b72f25d1027d55fd 481 Pfam PF02120 Flagellar hook-length control protein FliK 355 430 8.1E-22 T 06-07-2017 IPR021136 Flagellar hook-length control protein-like, C-terminal CAL12_RS00310 1d00e4167fbe5b05316fb1f869bd139e 299 SUPERFAMILY SSF88713 6 288 5.93E-55 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS00310 1d00e4167fbe5b05316fb1f869bd139e 299 Pfam PF01522 Polysaccharide deacetylase 65 175 2.5E-7 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS00310 1d00e4167fbe5b05316fb1f869bd139e 299 Gene3D G3DSA:3.20.20.370 6 288 2.1E-60 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS00030 4641c69c54e1d72b3091a53106dc7bd9 227 SUPERFAMILY SSF52499 4 206 4.71E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS00030 4641c69c54e1d72b3091a53106dc7bd9 227 Gene3D G3DSA:3.40.50.850 5 209 2.2E-44 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS00030 4641c69c54e1d72b3091a53106dc7bd9 227 Pfam PF00857 Isochorismatase family 15 168 2.6E-27 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS08395 6fc30b8d1f6032b179ac2cca23e6181d 371 Pfam PF17188 MucB/RseB C-terminal domain 266 361 1.5E-25 T 06-07-2017 IPR033436 MucB/RseB, C-terminal CAL12_RS08395 6fc30b8d1f6032b179ac2cca23e6181d 371 PIRSF PIRSF005427 36 368 4.2E-93 T 06-07-2017 IPR005588 MucB/RseB CAL12_RS08395 6fc30b8d1f6032b179ac2cca23e6181d 371 Pfam PF03888 MucB/RseB N-terminal domain 71 246 2.0E-57 T 06-07-2017 IPR033434 MucB/RseB, N-terminal CAL12_RS17850 099306e8507211133a0d8601d8379576 336 Gene3D G3DSA:3.90.1480.10 97 322 9.6E-17 T 06-07-2017 CAL12_RS17850 099306e8507211133a0d8601d8379576 336 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 96 327 1.0E-7 T 06-07-2017 CAL12_RS20265 aa36524a50fdbe9a86b6ca262c9308bc 348 Pfam PF13730 Helix-turn-helix domain 20 70 3.8E-6 T 06-07-2017 CAL12_RS00615 66dce3988e360eb330920d291141db8b 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 257 7.3E-11 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00615 66dce3988e360eb330920d291141db8b 285 Gene3D G3DSA:1.10.3720.10 13 260 8.2E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS00615 66dce3988e360eb330920d291141db8b 285 SUPERFAMILY SSF161098 10 261 3.14E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS08980 2294b0cd6b3c0f759e19ab10c23c2905 920 SUPERFAMILY SSF48208 430 655 8.5E-40 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS08980 2294b0cd6b3c0f759e19ab10c23c2905 920 SUPERFAMILY SSF48208 705 882 8.5E-40 T 06-07-2017 IPR008928 Six-hairpin glycosidase-like GO:0003824 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 Gene3D G3DSA:3.40.30.10 2 102 5.7E-33 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 PRINTS PR00421 Thioredoxin family signature 68 79 5.1E-9 T 06-07-2017 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 PRINTS PR00421 Thioredoxin family signature 21 29 5.1E-9 T 06-07-2017 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 PRINTS PR00421 Thioredoxin family signature 29 38 5.1E-9 T 06-07-2017 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 2.8E-29 T 06-07-2017 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 Pfam PF00085 Thioredoxin 3 101 4.5E-26 T 06-07-2017 IPR013766 Thioredoxin domain GO:0045454 CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 SUPERFAMILY SSF52833 2 103 3.06E-32 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS10950 cdcd284fad69bebbacc9358dd85c3b89 129 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 06-07-2017 IPR017937 Thioredoxin, conserved site GO:0045454 CAL12_RS06865 6efd15a86b18c7bd9497819255851426 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 282 3.9E-51 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS03025 76fd28ece2bbae79ca599cfca5fff869 468 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 254 456 6.8E-68 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS03025 76fd28ece2bbae79ca599cfca5fff869 468 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 248 4.0E-73 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS01895 62d9d971f1ed0a47e546b2f4f810c08d 393 Gene3D G3DSA:1.20.1250.20 5 186 8.6E-32 T 06-07-2017 CAL12_RS01895 62d9d971f1ed0a47e546b2f4f810c08d 393 SUPERFAMILY SSF103473 3 380 2.35E-62 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01895 62d9d971f1ed0a47e546b2f4f810c08d 393 Pfam PF07690 Major Facilitator Superfamily 9 318 1.7E-42 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01895 62d9d971f1ed0a47e546b2f4f810c08d 393 Gene3D G3DSA:1.20.1250.20 198 382 1.4E-13 T 06-07-2017 CAL12_RS14705 6224fec2deef7b842bc4c7f99cb81eaf 301 Gene3D G3DSA:3.90.850.10 80 300 1.8E-85 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14705 6224fec2deef7b842bc4c7f99cb81eaf 301 SUPERFAMILY SSF56529 76 299 2.09E-76 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS14705 6224fec2deef7b842bc4c7f99cb81eaf 301 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 87 299 1.9E-71 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS11400 9bef6ec63cf1dcea6ca4e16c46555c7c 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 2.1E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS04645 09ca785bfe556b28cb98697aba667b31 318 SUPERFAMILY SSF53850 90 282 7.6E-12 T 06-07-2017 CAL12_RS04645 09ca785bfe556b28cb98697aba667b31 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 311 2.6E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS04645 09ca785bfe556b28cb98697aba667b31 318 PIRSF PIRSF017082 2 318 1.9E-77 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS14060 c6b7ead27c67897d7d2b636dfdab9cbb 243 Gene3D G3DSA:3.90.226.10 1 239 7.8E-68 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14060 c6b7ead27c67897d7d2b636dfdab9cbb 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 228 2.5E-54 T 06-07-2017 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CAL12_RS14060 c6b7ead27c67897d7d2b636dfdab9cbb 243 SUPERFAMILY SSF52096 1 236 2.2E-69 T 06-07-2017 IPR029045 ClpP/crotonase-like domain CAL12_RS14060 c6b7ead27c67897d7d2b636dfdab9cbb 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 06-07-2017 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CAL12_RS06265 6f8d6b6990b162d26df49f82af64842f 406 SUPERFAMILY SSF75304 30 404 1.03E-81 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS06265 6f8d6b6990b162d26df49f82af64842f 406 Pfam PF01425 Amidase 36 201 1.8E-49 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS06265 6f8d6b6990b162d26df49f82af64842f 406 Gene3D G3DSA:3.90.1300.10 26 403 6.0E-87 T 06-07-2017 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CAL12_RS13555 a1f4d78d41687b9840d4451c71e4cf21 345 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 6 334 8.3E-34 T 06-07-2017 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CAL12_RS13555 a1f4d78d41687b9840d4451c71e4cf21 345 Gene3D G3DSA:3.20.20.210 4 342 6.5E-85 T 06-07-2017 CAL12_RS13555 a1f4d78d41687b9840d4451c71e4cf21 345 SUPERFAMILY SSF51726 7 342 2.22E-71 T 06-07-2017 CAL12_RS08850 3288a002bbb51d8b7abd6a11c18245de 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 280 1.7E-31 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS09530 31797fb0f4af84ec0da34b1f19091cc1 410 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 51 399 2.4E-38 T 06-07-2017 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX CAL12_RS04230 5c0b8464b273a1b019c648626374ce55 436 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 423 1.5E-48 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS04230 5c0b8464b273a1b019c648626374ce55 436 SUPERFAMILY SSF55205 1 433 2.45E-84 T 06-07-2017 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CAL12_RS04230 5c0b8464b273a1b019c648626374ce55 436 Gene3D G3DSA:3.65.10.10 227 432 1.5E-33 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS04230 5c0b8464b273a1b019c648626374ce55 436 Gene3D G3DSA:3.65.10.10 22 226 5.9E-44 T 06-07-2017 IPR001986 Enolpyruvate transferase domain GO:0016765 CAL12_RS19500 8f2f5709b456fd2025c4927f1480ac37 228 SUPERFAMILY SSF52317 1 216 3.05E-38 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS19500 8f2f5709b456fd2025c4927f1480ac37 228 Gene3D G3DSA:3.40.50.880 1 224 1.7E-68 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS19500 8f2f5709b456fd2025c4927f1480ac37 228 Pfam PF03575 Peptidase family S51 3 200 1.1E-50 T 06-07-2017 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CAL12_RS12860 d6c373f237bba9806b44895defbb90b9 367 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 321 3.9E-54 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS12860 d6c373f237bba9806b44895defbb90b9 367 SUPERFAMILY SSF53850 158 333 3.8E-6 T 06-07-2017 CAL12_RS12860 d6c373f237bba9806b44895defbb90b9 367 PIRSF PIRSF039026 1 358 2.0E-115 T 06-07-2017 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 574 4.1E-172 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 709 21.788 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 SUPERFAMILY SSF109604 354 500 7.32E-10 T 06-07-2017 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 Pfam PF05746 DALR anticodon binding domain 604 701 3.5E-5 T 06-07-2017 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 53 65 1.4E-30 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 332 348 1.4E-30 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 1.4E-30 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 408 427 1.4E-30 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 259 274 1.4E-30 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS06350 65367205bc89f4ea1908339ea5c5199f 711 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 6 709 6.4E-165 T 06-07-2017 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CAL12_RS26685 985721f6576659960b47c177a3564495 294 PIRSF PIRSF026649 1 279 1.2E-73 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAL12_RS26685 985721f6576659960b47c177a3564495 294 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 2 271 8.9E-31 T 06-07-2017 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CAL12_RS07975 11a48e9d02511230c9b0655e147119ef 452 Pfam PF04932 O-Antigen ligase 191 333 9.1E-10 T 06-07-2017 IPR007016 O-antigen ligase-related CAL12_RS25650 5a461258720f3dfe84126e4e8317c55d 176 Pfam PF09335 SNARE associated Golgi protein 56 166 1.0E-10 T 06-07-2017 IPR032816 SNARE associated Golgi protein CAL12_RS27400 cac633455b1cac262047bfaa95a1533c 394 Gene3D G3DSA:1.20.1250.20 215 392 4.4E-15 T 06-07-2017 CAL12_RS27400 cac633455b1cac262047bfaa95a1533c 394 Gene3D G3DSA:1.20.1250.20 15 190 4.0E-26 T 06-07-2017 CAL12_RS27400 cac633455b1cac262047bfaa95a1533c 394 Pfam PF07690 Major Facilitator Superfamily 24 242 7.4E-27 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS27400 cac633455b1cac262047bfaa95a1533c 394 SUPERFAMILY SSF103473 12 392 1.7E-56 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS26460 1bf5198a4bab0ca0b84c9afefde2e948 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 1.2E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 SUPERFAMILY SSF64518 130 551 9.81E-41 T 06-07-2017 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 483 551 6.9E-8 T 06-07-2017 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 366 9.2E-80 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 518 542 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 445 464 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 263 285 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 363 385 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 48 70 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 413 430 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS11935 0fc97993e5f77f016c11207fb933291e 552 PRINTS PR01005 Flagellar hook-associated protein signature 471 492 1.6E-46 T 06-07-2017 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CAL12_RS14645 ecb3893688423940c754f0d0243c0a89 291 SUPERFAMILY SSF51621 7 251 1.21E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS14645 ecb3893688423940c754f0d0243c0a89 291 Pfam PF13714 Phosphoenolpyruvate phosphomutase 15 244 2.2E-50 T 06-07-2017 CAL12_RS14645 ecb3893688423940c754f0d0243c0a89 291 Gene3D G3DSA:3.20.20.60 6 251 1.3E-59 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS13280 54798cc246d8072267eccca992c3d171 388 Gene3D G3DSA:3.40.50.10540 301 378 9.6E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS13280 54798cc246d8072267eccca992c3d171 388 Gene3D G3DSA:3.40.50.10540 2 212 9.6E-99 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS13280 54798cc246d8072267eccca992c3d171 388 SUPERFAMILY SSF89796 1 377 5.62E-119 T 06-07-2017 IPR023606 CoA-transferase family III domain CAL12_RS13280 54798cc246d8072267eccca992c3d171 388 Pfam PF02515 CoA-transferase family III 5 368 2.3E-109 T 06-07-2017 IPR003673 CoA-transferase family III GO:0003824 CAL12_RS13280 54798cc246d8072267eccca992c3d171 388 Gene3D G3DSA:3.30.1540.10 222 300 5.2E-23 T 06-07-2017 CAL12_RS11595 03e68a4623ac2c72fb9a6a1cc1dbaf69 300 SUPERFAMILY SSF161098 91 277 1.13E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11595 03e68a4623ac2c72fb9a6a1cc1dbaf69 300 Gene3D G3DSA:1.10.3720.10 86 293 4.1E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11595 03e68a4623ac2c72fb9a6a1cc1dbaf69 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 296 1.6E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11595 03e68a4623ac2c72fb9a6a1cc1dbaf69 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 70 4.5E-9 T 06-07-2017 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CAL12_RS12675 3c6b11b9e0b7f4442f585fefe8aba745 182 SUPERFAMILY SSF52016 25 167 9.89E-12 T 06-07-2017 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CAL12_RS26475 fbb46d0f7b471e5b000a31457b5c267a 209 Pfam PF01810 LysE type translocator 23 205 2.7E-22 T 06-07-2017 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 CAL12_RS23300 6e7e61847d24066c0b2f0bc54e055484 513 PIRSF PIRSF012702 3 509 9.1E-139 T 06-07-2017 IPR009197 Microcystin LR degradation protein MlrC CAL12_RS23300 6e7e61847d24066c0b2f0bc54e055484 513 Pfam PF07364 Metallopeptidase family M81 7 300 7.4E-75 T 06-07-2017 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CAL12_RS23300 6e7e61847d24066c0b2f0bc54e055484 513 Pfam PF07171 MlrC C-terminus 310 489 4.3E-38 T 06-07-2017 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CAL12_RS03220 f9f9e84e2c542e7e7cd369c48512de47 397 Gene3D G3DSA:3.20.20.70 59 330 1.1E-6 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS03220 f9f9e84e2c542e7e7cd369c48512de47 397 Pfam PF06187 Protein of unknown function (DUF993) 5 394 1.2E-184 T 06-07-2017 IPR009334 Protein of unknown function DUF993 CAL12_RS03220 f9f9e84e2c542e7e7cd369c48512de47 397 SUPERFAMILY SSF51569 59 340 1.88E-10 T 06-07-2017 CAL12_RS25350 801029ef9e241be6d6bafdb46144bf23 397 Pfam PF07690 Major Facilitator Superfamily 4 294 5.9E-21 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS25350 801029ef9e241be6d6bafdb46144bf23 397 Gene3D G3DSA:1.20.1250.20 197 390 6.9E-15 T 06-07-2017 CAL12_RS25350 801029ef9e241be6d6bafdb46144bf23 397 SUPERFAMILY SSF103473 3 393 4.84E-38 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS25350 801029ef9e241be6d6bafdb46144bf23 397 Gene3D G3DSA:1.20.1250.20 4 184 6.1E-12 T 06-07-2017 CAL12_RS04570 92a9c18089e8abaf62e5b8599c0e48e2 182 Pfam PF16970 Type-1 fimbrial protein, A 58 181 2.4E-21 T 06-07-2017 CAL12_RS04570 92a9c18089e8abaf62e5b8599c0e48e2 182 Gene3D G3DSA:2.60.40.1090 31 181 1.5E-28 T 06-07-2017 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 CAL12_RS04570 92a9c18089e8abaf62e5b8599c0e48e2 182 SUPERFAMILY SSF49401 32 181 3.88E-25 T 06-07-2017 IPR008966 Adhesion domain CAL12_RS21835 f2f766f0731796067ee0de85a36bc31b 116 Pfam PF01381 Helix-turn-helix 60 114 4.2E-9 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS21835 f2f766f0731796067ee0de85a36bc31b 116 SUPERFAMILY SSF47413 59 114 2.31E-11 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS21835 f2f766f0731796067ee0de85a36bc31b 116 Gene3D G3DSA:1.10.260.40 60 114 1.5E-12 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS21835 f2f766f0731796067ee0de85a36bc31b 116 SMART SM00530 59 114 2.0E-8 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS15705 c5132955b8ba8572dfc2f4e018568d9a 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 306 1.2E-36 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS02250 8d9b67f0a0cbe3ab449c9440e004c30d 280 Pfam PF01578 Cytochrome C assembly protein 62 276 2.0E-26 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAL12_RS03525 d6ae9c2d316ff4733ee243cbc146415b 155 Gene3D G3DSA:3.90.79.10 23 92 5.8E-13 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS03525 d6ae9c2d316ff4733ee243cbc146415b 155 Pfam PF00293 NUDIX domain 24 89 1.5E-12 T 06-07-2017 IPR000086 NUDIX hydrolase domain GO:0016787 CAL12_RS03525 d6ae9c2d316ff4733ee243cbc146415b 155 SUPERFAMILY SSF55811 22 140 3.11E-15 T 06-07-2017 IPR015797 NUDIX hydrolase domain-like GO:0016787 CAL12_RS15000 49426efb04d63ca99dc22846dee96c12 498 SUPERFAMILY SSF55931 354 478 4.32E-17 T 06-07-2017 CAL12_RS15000 49426efb04d63ca99dc22846dee96c12 498 SUPERFAMILY SSF55931 6 250 4.32E-17 T 06-07-2017 CAL12_RS15000 49426efb04d63ca99dc22846dee96c12 498 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 87 213 5.9E-10 T 06-07-2017 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CAL12_RS13290 4180e1aed10fb60bc49cfc56fc1474c2 370 SUPERFAMILY SSF51556 49 367 1.29E-70 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS13290 4180e1aed10fb60bc49cfc56fc1474c2 370 Gene3D G3DSA:3.20.20.140 50 367 8.3E-80 T 06-07-2017 CAL12_RS13290 4180e1aed10fb60bc49cfc56fc1474c2 370 Pfam PF04909 Amidohydrolase 50 367 2.9E-40 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS06990 73f3208452303d189942750723665bab 190 SUPERFAMILY SSF69118 1 174 5.12E-28 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS06990 73f3208452303d189942750723665bab 190 Gene3D G3DSA:1.20.1290.10 35 174 1.8E-19 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS09540 fbf6b5e7540478311cfb12e10726b938 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.377 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAL12_RS09540 fbf6b5e7540478311cfb12e10726b938 178 Pfam PF00719 Inorganic pyrophosphatase 18 172 1.9E-53 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAL12_RS09540 fbf6b5e7540478311cfb12e10726b938 178 SUPERFAMILY SSF50324 4 174 2.88E-67 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAL12_RS09540 fbf6b5e7540478311cfb12e10726b938 178 Gene3D G3DSA:3.90.80.10 4 174 1.1E-61 T 06-07-2017 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 CAL12_RS02580 dceaac2b7c6d89020dbed9657ef8a68d 175 Pfam PF03724 META domain 47 168 1.7E-20 T 06-07-2017 IPR005184 Domain of unknown function DUF306, Meta/HslJ CAL12_RS02545 e9af1358b9dcf8965f20aa800aec1a55 462 Pfam PF13520 Amino acid permease 29 436 7.0E-56 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAL12_RS02545 e9af1358b9dcf8965f20aa800aec1a55 462 PIRSF PIRSF006060 26 457 3.1E-75 T 06-07-2017 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CAL12_RS08345 938374440e92e61cbbd78541acd5eaec 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.236 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08345 938374440e92e61cbbd78541acd5eaec 60 Pfam PF01783 Ribosomal L32p protein family 2 55 1.2E-19 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08345 938374440e92e61cbbd78541acd5eaec 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 4.5E-21 T 06-07-2017 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CAL12_RS08345 938374440e92e61cbbd78541acd5eaec 60 SUPERFAMILY SSF57829 2 55 5.37E-18 T 06-07-2017 IPR011332 Zinc-binding ribosomal protein GO:0006412 CAL12_RS24835 cec81aa4a721c75f3446215136899826 167 Pfam PF07382 Histone H1-like nucleoprotein HC2 4 166 1.9E-21 T 06-07-2017 IPR009970 Histone H1-like nucleoprotein HC2 GO:0003677|GO:0030261 CAL12_RS09895 1c89649fb7c5e2ff848366758bd271d0 103 Pfam PF14330 Domain of unknown function (DUF4387) 4 100 5.5E-35 T 06-07-2017 IPR025496 Protein of unknown function DUF4387 CAL12_RS19530 afbb4ff55b397f0a6912f55e398e0b0b 198 Pfam PF02361 Cobalt transport protein 24 197 3.0E-19 T 06-07-2017 IPR003339 ABC/ECF transporter, transmembrane component CAL12_RS15080 96c19f2b15a5d4bfce0128f8fe0f4eb0 313 Gene3D G3DSA:1.10.3720.10 89 304 4.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15080 96c19f2b15a5d4bfce0128f8fe0f4eb0 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 8.2E-41 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS15080 96c19f2b15a5d4bfce0128f8fe0f4eb0 313 SUPERFAMILY SSF161098 94 297 8.76E-23 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS22340 b727842f02cc64389a5c04d5aaf6af30 179 SUPERFAMILY SSF51182 53 163 1.2E-34 T 06-07-2017 IPR011051 RmlC-like cupin domain CAL12_RS22340 b727842f02cc64389a5c04d5aaf6af30 179 Gene3D G3DSA:2.60.120.10 55 165 3.2E-33 T 06-07-2017 IPR014710 RmlC-like jelly roll fold CAL12_RS22340 b727842f02cc64389a5c04d5aaf6af30 179 Pfam PF05995 Cysteine dioxygenase type I 69 158 3.2E-14 T 06-07-2017 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CAL12_RS21605 75cc0bd592ee84e44a6304afb6477e8d 258 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 33 258 1.3E-71 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAL12_RS21605 75cc0bd592ee84e44a6304afb6477e8d 258 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 18 258 1.1E-67 T 06-07-2017 IPR010239 Conserved hypothetical protein CHP02001 CAL12_RS17270 fc11f7e8dba21c284aa125a5e29a5d8b 402 Pfam PF01610 Transposase 281 401 8.6E-8 T 06-07-2017 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain CAL12_RS17270 fc11f7e8dba21c284aa125a5e29a5d8b 402 Pfam PF00487 Fatty acid desaturase 17 229 4.1E-13 T 06-07-2017 IPR005804 Fatty acid desaturase domain GO:0006629 CAL12_RS13755 5ea3d04fb1ed797d873ccdfd1e0b9215 318 Gene3D G3DSA:1.10.3720.10 118 307 8.5E-20 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13755 5ea3d04fb1ed797d873ccdfd1e0b9215 318 SUPERFAMILY SSF161098 117 294 3.14E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS13755 5ea3d04fb1ed797d873ccdfd1e0b9215 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 309 3.1E-21 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS11290 b764980039d9702209c8db9ca93c6bdf 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 2.2E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS20795 9878380445374c88e32df2d3f7e92410 295 SUPERFAMILY SSF56529 71 288 4.32E-58 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS20795 9878380445374c88e32df2d3f7e92410 295 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 79 284 3.8E-53 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS20795 9878380445374c88e32df2d3f7e92410 295 Gene3D G3DSA:3.90.850.10 69 288 7.3E-70 T 06-07-2017 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 06-07-2017 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 PIRSF PIRSF039085 1 244 6.8E-100 T 06-07-2017 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 Gene3D G3DSA:3.40.50.300 1 230 2.6E-77 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 Pfam PF00005 ABC transporter 18 165 1.2E-35 T 06-07-2017 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 SMART SM00382 26 213 1.4E-15 T 06-07-2017 IPR003593 AAA+ ATPase domain CAL12_RS27705 dcd005956d7855ad4d2bf5615cb5daf6 245 SUPERFAMILY SSF52540 1 229 1.45E-73 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS08095 94d38d69e37824c73f0445141b0d51d4 196 Pfam PF00565 Staphylococcal nuclease homologue 62 169 3.0E-18 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAL12_RS08095 94d38d69e37824c73f0445141b0d51d4 196 SMART SM00318 36 169 2.2E-28 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAL12_RS08095 94d38d69e37824c73f0445141b0d51d4 196 SUPERFAMILY SSF50199 35 176 1.57E-32 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAL12_RS08095 94d38d69e37824c73f0445141b0d51d4 196 Gene3D G3DSA:2.40.50.90 36 172 1.4E-27 T 06-07-2017 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CAL12_RS08095 94d38d69e37824c73f0445141b0d51d4 196 ProSitePatterns PS01123 Thermonuclease family signature 1. 47 72 - T 06-07-2017 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 CAL12_RS19920 8998334b3325550d097737f63109387f 298 Pfam PF13560 Helix-turn-helix domain 29 107 6.5E-18 T 06-07-2017 CAL12_RS19920 8998334b3325550d097737f63109387f 298 Gene3D G3DSA:1.10.260.40 27 100 7.6E-16 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS19920 8998334b3325550d097737f63109387f 298 SUPERFAMILY SSF47413 52 98 3.97E-7 T 06-07-2017 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CAL12_RS19920 8998334b3325550d097737f63109387f 298 SMART SM00530 33 104 2.1E-7 T 06-07-2017 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CAL12_RS21555 2391eb50213a7ba539bba53e32f9a0c3 243 SMART SM00463 152 236 5.1E-16 T 06-07-2017 IPR002625 Smr domain CAL12_RS21555 2391eb50213a7ba539bba53e32f9a0c3 243 Pfam PF01713 Smr domain 155 236 2.3E-25 T 06-07-2017 IPR002625 Smr domain CAL12_RS21555 2391eb50213a7ba539bba53e32f9a0c3 243 SUPERFAMILY SSF160443 153 236 2.09E-17 T 06-07-2017 IPR002625 Smr domain CAL12_RS07685 b7dc6d31d458806c2f7c2e726763a90d 59 Pfam PF12244 Protein of unknown function (DUF3606) 5 58 2.3E-24 T 06-07-2017 IPR022037 Protein of unknown function DUF3606 CAL12_RS04960 27c853f8df7cc4dc8d92df1c549c7f80 104 Pfam PF05957 Bacterial protein of unknown function (DUF883) 12 104 4.2E-31 T 06-07-2017 IPR010279 Protein of unknown function DUF883, ElaB CAL12_RS12830 c6ecc216f308bea69779e37dbaa0ddbc 345 SUPERFAMILY SSF144052 114 341 7.59E-17 T 06-07-2017 CAL12_RS27940 35f1393eb4d69b992a4e027485032718 155 Pfam PF01638 HxlR-like helix-turn-helix 47 134 6.3E-27 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS27940 35f1393eb4d69b992a4e027485032718 155 SUPERFAMILY SSF46785 31 134 1.36E-28 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS27940 35f1393eb4d69b992a4e027485032718 155 Gene3D G3DSA:1.10.10.10 24 141 2.9E-41 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS05400 c3fb896e10454516d7beaad42291a29b 214 Gene3D G3DSA:3.10.490.10 35 199 1.8E-28 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS05400 c3fb896e10454516d7beaad42291a29b 214 Pfam PF04752 ChaC-like protein 39 205 6.7E-45 T 06-07-2017 IPR006840 ChaC-like protein Reactome: R-HSA-174403 CAL12_RS05400 c3fb896e10454516d7beaad42291a29b 214 SUPERFAMILY SSF110857 39 151 8.11E-12 T 06-07-2017 IPR013024 Butirosin biosynthesis, BtrG-like CAL12_RS04375 65c9eeb6f1f7b31df033d1ed46a65d26 100 Pfam PF12779 YXWGXW repeat (2 copies) 47 72 1.1E-8 T 06-07-2017 IPR024447 YXWGXW repeat CAL12_RS04375 65c9eeb6f1f7b31df033d1ed46a65d26 100 Pfam PF12779 YXWGXW repeat (2 copies) 75 100 4.2E-5 T 06-07-2017 IPR024447 YXWGXW repeat CAL12_RS05255 893d3554424a532480e06eac2dd5f985 315 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 262 5.6E-35 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS16810 e9e3a1b20064b957643312079c2f2b3d 95 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 7 37 1.9E-5 T 06-07-2017 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CAL12_RS24615 9d98255f85a1d90f0b6fff0958cd266c 122 SUPERFAMILY SSF46785 50 100 6.21E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS24615 9d98255f85a1d90f0b6fff0958cd266c 122 Gene3D G3DSA:1.10.10.10 54 105 2.2E-7 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS21525 f41f155a34801249faeddeb74ae8460e 378 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 100 374 2.3E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS21525 f41f155a34801249faeddeb74ae8460e 378 SUPERFAMILY SSF53850 161 339 7.78E-10 T 06-07-2017 CAL12_RS22800 108ec2c3ca237d5fe94486e71cb1a51d 227 Pfam PF16357 Putative PepSY_TM-like 31 226 6.8E-16 T 06-07-2017 IPR032307 Putative PepSY TM-like protein CAL12_RS07965 7aee3fb7cfe51840da22d683d5bc80a0 297 Gene3D G3DSA:3.90.550.10 5 173 7.4E-9 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07965 7aee3fb7cfe51840da22d683d5bc80a0 297 SUPERFAMILY SSF53448 179 206 7.69E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07965 7aee3fb7cfe51840da22d683d5bc80a0 297 SUPERFAMILY SSF53448 5 147 7.69E-20 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS07965 7aee3fb7cfe51840da22d683d5bc80a0 297 Pfam PF00535 Glycosyl transferase family 2 7 131 2.5E-14 T 06-07-2017 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CAL12_RS07355 1f414874bf050fc0636e3e95cc9ebbfc 457 Pfam PF05359 Domain of Unknown Function (DUF748) 238 372 1.7E-18 T 06-07-2017 IPR008023 Protein of unknown function DUF748 CAL12_RS13125 357082f7194ec76eb13e33b5162c0f51 325 PIRSF PIRSF017082 1 324 9.2E-76 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13125 357082f7194ec76eb13e33b5162c0f51 325 SUPERFAMILY SSF53850 116 281 1.01E-11 T 06-07-2017 CAL12_RS13125 357082f7194ec76eb13e33b5162c0f51 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 320 7.6E-69 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS02510 5bc69b419be9e4919dd088ac0518491b 288 Pfam PF13847 Methyltransferase domain 86 215 2.1E-10 T 06-07-2017 IPR025714 Methyltransferase domain CAL12_RS02510 5bc69b419be9e4919dd088ac0518491b 288 Gene3D G3DSA:3.40.50.150 67 192 7.8E-24 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS02510 5bc69b419be9e4919dd088ac0518491b 288 SUPERFAMILY SSF53335 61 192 8.81E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS17380 7de4d654ba000110387fbf84b4e289f4 450 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 7 410 3.3E-82 T 06-07-2017 IPR005219 Conserved hypothetical protein CHP00155 CAL12_RS17380 7de4d654ba000110387fbf84b4e289f4 450 Pfam PF04403 Paraquat-inducible protein A 48 197 6.9E-39 T 06-07-2017 IPR007498 Paraquat-inducible protein A CAL12_RS17380 7de4d654ba000110387fbf84b4e289f4 450 Pfam PF04403 Paraquat-inducible protein A 255 410 3.0E-54 T 06-07-2017 IPR007498 Paraquat-inducible protein A CAL12_RS27885 401470e85e0d3b93640c4d6ba4d7a0a3 404 SUPERFAMILY SSF103473 17 397 6.02E-54 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS27885 401470e85e0d3b93640c4d6ba4d7a0a3 404 Pfam PF07690 Major Facilitator Superfamily 31 361 3.7E-29 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS27885 401470e85e0d3b93640c4d6ba4d7a0a3 404 Gene3D G3DSA:1.20.1250.20 219 397 3.7E-12 T 06-07-2017 CAL12_RS27885 401470e85e0d3b93640c4d6ba4d7a0a3 404 Gene3D G3DSA:1.20.1250.20 25 201 2.1E-23 T 06-07-2017 CAL12_RS22795 821de43b9538739b7e6a0ca6a031f441 387 SUPERFAMILY SSF53335 175 321 2.39E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22795 821de43b9538739b7e6a0ca6a031f441 387 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 272 278 - T 06-07-2017 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CAL12_RS22795 821de43b9538739b7e6a0ca6a031f441 387 Gene3D G3DSA:3.40.50.150 157 353 1.3E-30 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS22795 821de43b9538739b7e6a0ca6a031f441 387 Pfam PF05175 Methyltransferase small domain 208 283 3.0E-10 T 06-07-2017 IPR007848 Methyltransferase small domain GO:0008168 CAL12_RS12755 6e055bdeb0ca3f7aa4063ab81f2d65e4 264 SMART SM00364 172 191 11.0 T 06-07-2017 CAL12_RS12755 6e055bdeb0ca3f7aa4063ab81f2d65e4 264 SMART SM00364 151 170 3.2 T 06-07-2017 CAL12_RS12755 6e055bdeb0ca3f7aa4063ab81f2d65e4 264 SMART SM00364 110 129 240.0 T 06-07-2017 CAL12_RS12755 6e055bdeb0ca3f7aa4063ab81f2d65e4 264 Gene3D G3DSA:3.80.10.10 95 205 1.7E-19 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS12755 6e055bdeb0ca3f7aa4063ab81f2d65e4 264 SUPERFAMILY SSF52058 96 204 2.49E-14 T 06-07-2017 IPR032675 Leucine-rich repeat domain, L domain-like CAL12_RS15505 0255a2d79431b1f51f943dd7a02dd0c2 208 SUPERFAMILY SSF52540 4 202 1.05E-50 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15505 0255a2d79431b1f51f943dd7a02dd0c2 208 Gene3D G3DSA:3.40.50.300 4 205 1.3E-66 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS15505 0255a2d79431b1f51f943dd7a02dd0c2 208 Pfam PF02223 Thymidylate kinase 10 193 7.7E-47 T 06-07-2017 CAL12_RS15505 0255a2d79431b1f51f943dd7a02dd0c2 208 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 192 2.3E-48 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAL12_RS15505 0255a2d79431b1f51f943dd7a02dd0c2 208 Hamap MF_00165 Thymidylate kinase [tmk]. 6 204 28.33 T 06-07-2017 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 SUPERFAMILY SSF103473 226 435 1.01E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 SUPERFAMILY SSF103473 3 180 1.01E-55 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 Pfam PF07690 Major Facilitator Superfamily 4 386 1.2E-44 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 Gene3D G3DSA:1.20.1250.20 242 436 2.5E-13 T 06-07-2017 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 Gene3D G3DSA:1.20.1250.20 2 172 1.3E-30 T 06-07-2017 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 377 396 1.5E-7 T 06-07-2017 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 85 105 1.5E-7 T 06-07-2017 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 180 198 1.5E-7 T 06-07-2017 CAL12_RS05845 80c65b8292b0864157964e7314abca60 449 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 139 1.5E-7 T 06-07-2017 CAL12_RS03530 709550e02fadd341e740c45348e9b42e 187 Gene3D G3DSA:3.40.50.850 7 152 1.7E-38 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS03530 709550e02fadd341e740c45348e9b42e 187 SUPERFAMILY SSF52499 6 181 4.97E-41 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS03530 709550e02fadd341e740c45348e9b42e 187 Pfam PF00857 Isochorismatase family 11 146 1.9E-33 T 06-07-2017 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CAL12_RS10375 5ed6566422face43f02beb8097ca8a29 347 SUPERFAMILY SSF144052 19 337 1.06E-17 T 06-07-2017 CAL12_RS23090 70d07787d864ca2af6c062912297fdc8 117 SUPERFAMILY SSF54909 1 112 5.09E-33 T 06-07-2017 IPR011008 Dimeric alpha-beta barrel CAL12_RS23090 70d07787d864ca2af6c062912297fdc8 117 Pfam PF03795 YCII-related domain 1 111 7.6E-19 T 06-07-2017 IPR005545 YCII-related CAL12_RS23090 70d07787d864ca2af6c062912297fdc8 117 Gene3D G3DSA:3.30.70.1060 1 113 6.4E-37 T 06-07-2017 CAL12_RS03065 48c4d234b14f665b39b08e735498df48 273 SUPERFAMILY SSF161098 64 251 3.92E-25 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03065 48c4d234b14f665b39b08e735498df48 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 270 4.3E-28 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS03065 48c4d234b14f665b39b08e735498df48 273 Gene3D G3DSA:1.10.3720.10 59 268 1.9E-29 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27905 648d257356b8d39205d275183be00fdd 324 SUPERFAMILY SSF161098 90 304 4.41E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27905 648d257356b8d39205d275183be00fdd 324 Gene3D G3DSA:1.10.3720.10 89 316 3.4E-19 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS27905 648d257356b8d39205d275183be00fdd 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 5.0E-40 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS14915 cd50cd4d605ab7ffe1a0a9541e8d2e90 254 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 108 187 8.5E-13 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14915 cd50cd4d605ab7ffe1a0a9541e8d2e90 254 Gene3D G3DSA:1.10.760.10 96 194 7.3E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS14915 cd50cd4d605ab7ffe1a0a9541e8d2e90 254 SUPERFAMILY SSF46626 93 191 2.03E-18 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS08280 3d38993685b589caa9b13410e3958daf 140 Pfam PF07681 DoxX 10 95 2.7E-13 T 06-07-2017 IPR032808 DoxX family CAL12_RS12495 7d038b3ad1b010cc12c33ce992b54757 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 306 1.7E-43 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS04395 b5ecef48bccbe88696113c3c174d3a5a 449 Pfam PF08811 Protein of unknown function (DUF1800) 11 448 2.9E-130 T 06-07-2017 IPR014917 Protein of unknown function DUF1800 CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 Gene3D G3DSA:3.40.190.10 169 265 4.1E-24 T 06-07-2017 CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 Pfam PF03466 LysR substrate binding domain 91 295 1.3E-46 T 06-07-2017 IPR005119 LysR, substrate-binding CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 Gene3D G3DSA:1.10.10.10 6 89 6.6E-24 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 SUPERFAMILY SSF53850 91 300 4.65E-47 T 06-07-2017 CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 SUPERFAMILY SSF46785 6 90 6.99E-21 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.5E-18 T 06-07-2017 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CAL12_RS19780 cac34e8165d3b089429a3ff37f4ce376 322 Gene3D G3DSA:3.40.190.10 92 168 2.9E-5 T 06-07-2017 CAL12_RS20400 27054fbb000a7b374ca49d73ed5731d5 99 Gene3D G3DSA:3.40.50.2300 40 95 3.4E-7 T 06-07-2017 CAL12_RS20400 27054fbb000a7b374ca49d73ed5731d5 99 SUPERFAMILY SSF52172 40 94 5.27E-8 T 06-07-2017 IPR011006 CheY-like superfamily CAL12_RS10750 2c34121bf96ef6e61a379317e0665866 153 Pfam PF07007 Protein of unknown function (DUF1311) 56 150 4.8E-13 T 06-07-2017 IPR009739 Protein of unknown function DUF1311 CAL12_RS11300 9e2dc3e84dabe8c675899446d260f143 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 1.1E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS15365 65c588f55eb1a7b40fb636e3103996c4 488 Pfam PF07690 Major Facilitator Superfamily 22 418 8.0E-40 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS15365 65c588f55eb1a7b40fb636e3103996c4 488 Gene3D G3DSA:1.20.1250.20 271 474 2.9E-14 T 06-07-2017 CAL12_RS15365 65c588f55eb1a7b40fb636e3103996c4 488 Gene3D G3DSA:1.20.1250.20 16 200 4.5E-28 T 06-07-2017 CAL12_RS15365 65c588f55eb1a7b40fb636e3103996c4 488 SUPERFAMILY SSF103473 12 203 1.44E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS15365 65c588f55eb1a7b40fb636e3103996c4 488 SUPERFAMILY SSF103473 256 475 1.44E-50 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12290 472fe40edd37fae8cff1b5e7b25890a4 114 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 15 104 7.9E-24 T 06-07-2017 IPR009241 Toxin HigB-like CAL12_RS21290 cdc9a09800138b13148c0e6a883ccaca 135 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 29 125 1.5E-33 T 06-07-2017 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 CAL12_RS21290 cdc9a09800138b13148c0e6a883ccaca 135 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 37 109 1.7E-18 T 06-07-2017 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 CAL12_RS13480 03cbaef00e462800d7e9968b8846f05d 358 Pfam PF01594 Domain of unknown function DUF20 15 345 1.4E-34 T 06-07-2017 IPR002549 Transmembrane protein TqsA-like CAL12_RS24455 909c431627f00a2b479b8a59c93b5d14 273 Pfam PF10002 Predicted membrane protein (DUF2243) 21 160 4.4E-41 T 06-07-2017 IPR018719 Protein of unknown function DUF2243, membrane CAL12_RS21060 ffa5b5e0abc32d19a35a6d667d492dbf 138 Pfam PF05232 Chlorhexidine efflux transporter 74 136 1.8E-18 T 06-07-2017 IPR007896 Chlorhexidine efflux transporter CAL12_RS21060 ffa5b5e0abc32d19a35a6d667d492dbf 138 Pfam PF05232 Chlorhexidine efflux transporter 8 68 1.8E-17 T 06-07-2017 IPR007896 Chlorhexidine efflux transporter CAL12_RS16490 51607b3af4a0bdddab73dc6a3bdb5b2a 256 Pfam PF01904 Protein of unknown function DUF72 35 247 8.0E-56 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS16490 51607b3af4a0bdddab73dc6a3bdb5b2a 256 SUPERFAMILY SSF117396 14 250 3.27E-71 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS16490 51607b3af4a0bdddab73dc6a3bdb5b2a 256 Gene3D G3DSA:3.20.20.410 10 251 6.8E-72 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS01295 f51eb490ba7c061fb3023004851d5185 414 SUPERFAMILY SSF103473 10 412 2.62E-37 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS01295 f51eb490ba7c061fb3023004851d5185 414 Pfam PF07690 Major Facilitator Superfamily 22 257 1.6E-15 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01295 f51eb490ba7c061fb3023004851d5185 414 Pfam PF07690 Major Facilitator Superfamily 279 411 1.0E-8 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01295 f51eb490ba7c061fb3023004851d5185 414 Gene3D G3DSA:1.20.1250.20 22 194 6.8E-15 T 06-07-2017 CAL12_RS01295 f51eb490ba7c061fb3023004851d5185 414 Gene3D G3DSA:1.20.1250.20 230 407 7.5E-15 T 06-07-2017 CAL12_RS01120 26a0ef9defb89b8b0aacd2e2141bf84a 357 SUPERFAMILY SSF144052 137 340 1.7E-17 T 06-07-2017 CAL12_RS19130 2e0c3a5506ff5fc929d874aff95cb3e4 114 Pfam PF04972 BON domain 43 110 2.5E-20 T 06-07-2017 IPR007055 BON domain CAL12_RS19130 2e0c3a5506ff5fc929d874aff95cb3e4 114 SMART SM00749 48 111 5.4E-9 T 06-07-2017 IPR014004 Transport-associated and nodulation domain, bacteria CAL12_RS20985 91f5a0311665c19b7321165dd62aa29b 342 PIRSF PIRSF017082 9 342 1.3E-75 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20985 91f5a0311665c19b7321165dd62aa29b 342 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 338 1.7E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS20985 91f5a0311665c19b7321165dd62aa29b 342 SUPERFAMILY SSF53850 132 302 2.39E-12 T 06-07-2017 CAL12_RS02330 a27ba2e634cb97f231cae0de917f7eea 121 Pfam PF13663 Domain of unknown function (DUF4148) 15 82 1.5E-10 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS26820 71b4efaff138c531b732df36c0d7e1ec 318 Pfam PF02470 MlaD protein 44 112 2.0E-10 T 06-07-2017 IPR003399 Mce/MlaD CAL12_RS06800 ef282d600074af962ccd27bcf1a0433e 325 PIRSF PIRSF017082 1 325 3.0E-73 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06800 ef282d600074af962ccd27bcf1a0433e 325 SUPERFAMILY SSF53850 113 282 3.76E-11 T 06-07-2017 CAL12_RS06800 ef282d600074af962ccd27bcf1a0433e 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 3.4E-82 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS19905 ca689e838db5669061c8b42a39eefa0a 144 Pfam PF04120 Low affinity iron permease 5 119 1.2E-51 T 06-07-2017 IPR007251 Low affinity iron permease, Fet4 GO:0055085 CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 PIRSF PIRSF023956 1 231 8.8E-68 T 06-07-2017 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 228 1.6E-74 T 06-07-2017 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 229 2.9E-69 T 06-07-2017 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 229 37.542 T 06-07-2017 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 SUPERFAMILY SSF53335 1 229 9.91E-53 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS19790 bfb4cd8c73c41fd2c4b0df5a7f585867 231 Gene3D G3DSA:3.40.50.150 17 229 4.2E-57 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS15565 f7ec42c515eb339a02a8f6d48136702f 172 Pfam PF12779 YXWGXW repeat (2 copies) 128 148 0.056 T 06-07-2017 IPR024447 YXWGXW repeat CAL12_RS15565 f7ec42c515eb339a02a8f6d48136702f 172 Pfam PF12779 YXWGXW repeat (2 copies) 95 120 1.1E-6 T 06-07-2017 IPR024447 YXWGXW repeat CAL12_RS00180 9b160d2714beefd9babf374ff4897a48 356 SUPERFAMILY SSF53850 142 318 5.07E-12 T 06-07-2017 CAL12_RS00180 9b160d2714beefd9babf374ff4897a48 356 PIRSF PIRSF017082 27 355 3.1E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS00180 9b160d2714beefd9babf374ff4897a48 356 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 79 352 1.3E-71 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05790 7e0dc6576d13a0815f1a1c29f9bb6754 510 Gene3D G3DSA:2.70.98.10 207 363 2.4E-11 T 06-07-2017 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0003824|GO:0005975|GO:0030246 CAL12_RS05790 7e0dc6576d13a0815f1a1c29f9bb6754 510 Pfam PF01263 Aldose 1-epimerase 206 493 2.6E-30 T 06-07-2017 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CAL12_RS05790 7e0dc6576d13a0815f1a1c29f9bb6754 510 SUPERFAMILY SSF74650 205 494 2.32E-44 T 06-07-2017 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CAL12_RS06960 dff8ee9efb04b1ff9b44114186e41a06 397 Pfam PF08309 LVIVD repeat 154 168 0.087 T 06-07-2017 IPR013211 LVIVD CAL12_RS06960 dff8ee9efb04b1ff9b44114186e41a06 397 Pfam PF08309 LVIVD repeat 209 235 0.066 T 06-07-2017 IPR013211 LVIVD CAL12_RS05535 7f8a0f9df85d5c4f92880732543a732e 344 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 20 334 1.9E-62 T 06-07-2017 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CAL12_RS27340 666828e2c4b7a0f2eb6bdcdc5c2162e2 200 Pfam PF04612 Type II secretion system (T2SS), protein M 26 188 1.9E-26 T 06-07-2017 IPR007690 Type II secretion system, protein M GO:0006858 CAL12_RS11340 39cb26dbcd888193c7743d43366cd561 130 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 31 130 8.1E-34 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS19365 7671fb5892a5cc6a1aa6548676f370ff 183 SUPERFAMILY SSF69118 2 174 4.97E-27 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS19365 7671fb5892a5cc6a1aa6548676f370ff 183 Gene3D G3DSA:1.20.1290.10 35 175 1.3E-19 T 06-07-2017 IPR029032 AhpD-like Reactome: R-HSA-5628897 CAL12_RS04350 b992372a260ee3c680c98f5e06d84c5f 67 Pfam PF14070 Putative motility protein 11 64 5.6E-7 T 06-07-2017 IPR025906 Putative motility protein CAL12_RS23070 91b8744a98d13af730dba53aa9827294 239 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 9 236 2.5E-71 T 06-07-2017 IPR018715 Protein of unknown function DUF2239 CAL12_RS10940 2c65cb89bdc4b425c54b662cc43718c5 424 Gene3D G3DSA:1.20.1250.20 21 199 9.7E-15 T 06-07-2017 CAL12_RS10940 2c65cb89bdc4b425c54b662cc43718c5 424 Gene3D G3DSA:1.20.1250.20 222 394 7.2E-19 T 06-07-2017 CAL12_RS10940 2c65cb89bdc4b425c54b662cc43718c5 424 SUPERFAMILY SSF103473 21 396 1.57E-39 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS10940 2c65cb89bdc4b425c54b662cc43718c5 424 Pfam PF07690 Major Facilitator Superfamily 229 392 1.2E-12 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS20370 bc7146f64cc498d4fb1346d5f23486c4 426 Pfam PF00999 Sodium/hydrogen exchanger family 13 425 4.1E-35 T 06-07-2017 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CAL12_RS09590 2b3b129a88c71113ead44df87004de76 281 Pfam PF00482 Type II secretion system (T2SS), protein F 115 238 2.9E-18 T 06-07-2017 IPR018076 Type II secretion system F domain CAL12_RS11505 6b07118c857986338d79df87048dda8f 139 Gene3D G3DSA:2.60.40.60 31 127 4.2E-4 T 06-07-2017 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 CAL12_RS11505 6b07118c857986338d79df87048dda8f 139 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 45 135 3.0E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS13785 1f274c0a011d934968192b6c40fac57d 470 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 114 168 5.3E-7 T 06-07-2017 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CAL12_RS13785 1f274c0a011d934968192b6c40fac57d 470 SUPERFAMILY SSF52317 115 286 2.22E-13 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS13785 1f274c0a011d934968192b6c40fac57d 470 Gene3D G3DSA:3.40.50.880 111 285 7.8E-12 T 06-07-2017 IPR029062 Class I glutamine amidotransferase-like CAL12_RS09495 18f2e047da50f6187c0e530637fba1f0 198 Pfam PF11136 Protein of unknown function (DUF2889) 14 138 7.3E-45 T 06-07-2017 IPR021312 Protein of unknown function DUF2889 CAL12_RS17410 ef2b91647308c34fa42a5d4316546b04 155 Pfam PF02643 Uncharacterized ACR, COG1430 50 151 3.8E-34 T 06-07-2017 IPR003795 Protein of unknown function DUF192 CAL12_RS11530 a19613903b9c7720d78b6d3d9c2c0441 158 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 2 34 6.9E-6 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11530 a19613903b9c7720d78b6d3d9c2c0441 158 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 62 158 9.1E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS00860 eb47231f5ef92857fe9c79b8d30a3a78 259 Pfam PF01061 ABC-2 type transporter 14 222 5.3E-35 T 06-07-2017 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CAL12_RS00860 eb47231f5ef92857fe9c79b8d30a3a78 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 5.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS00860 eb47231f5ef92857fe9c79b8d30a3a78 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 5.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS00860 eb47231f5ef92857fe9c79b8d30a3a78 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 61 83 5.5E-8 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS00860 eb47231f5ef92857fe9c79b8d30a3a78 259 PIRSF PIRSF006648 6 255 9.0E-22 T 06-07-2017 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CAL12_RS17440 922ef335b5e8b023b89a8b39e30de06e 136 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 134 1.7E-24 T 06-07-2017 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 CAL12_RS17440 922ef335b5e8b023b89a8b39e30de06e 136 Gene3D G3DSA:3.90.550.10 77 121 4.3E-4 T 06-07-2017 IPR029044 Nucleotide-diphospho-sugar transferases CAL12_RS17105 221f46d7e57c10cd4acf55a092120083 426 Pfam PF02687 FtsX-like permease family 286 419 6.9E-20 T 06-07-2017 IPR003838 ABC transporter permease protein domain GO:0016020 CAL12_RS17105 221f46d7e57c10cd4acf55a092120083 426 Pfam PF12704 MacB-like periplasmic core domain 38 255 1.7E-21 T 06-07-2017 IPR025857 MacB-like periplasmic core domain CAL12_RS17105 221f46d7e57c10cd4acf55a092120083 426 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 6 425 1.8E-142 T 06-07-2017 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 CAL12_RS09020 f3bf70ee8ecbd4dc0a520d1bd44bcf77 372 Gene3D G3DSA:3.40.50.1820 6 336 9.1E-41 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS09020 f3bf70ee8ecbd4dc0a520d1bd44bcf77 372 SUPERFAMILY SSF53474 42 271 1.89E-7 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS11310 f645416e4fd514ffae5fcca3805017b4 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 132 4.2E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS15200 3b5a487db3e8852acfdcaeb8aee69f5b 452 Pfam PF04412 Protein of unknown function (DUF521) 3 440 1.3E-136 T 06-07-2017 IPR007506 Domain of unknown function DUF521 CAL12_RS00330 763a5d56dba58e705f907194e6dbb9d8 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 276 1.9E-37 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS07940 bc7d42d37c8ec047211e9b7bbe8b86ab 542 SUPERFAMILY SSF75005 301 533 4.38E-15 T 06-07-2017 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CAL12_RS06565 999e3b7216ccbe901b48c49507fafb8c 284 Gene3D G3DSA:3.40.630.30 30 231 3.3E-31 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS06565 999e3b7216ccbe901b48c49507fafb8c 284 SUPERFAMILY SSF55729 28 234 5.78E-41 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS06565 999e3b7216ccbe901b48c49507fafb8c 284 Pfam PF13444 Acetyltransferase (GNAT) domain 43 144 2.0E-32 T 06-07-2017 CAL12_RS25050 5a5c2ca2927d3440a3530c7ffa86e980 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 293 1.5E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS01820 d843c9323f53dc609138d69469408f8a 430 Pfam PF07690 Major Facilitator Superfamily 29 214 7.2E-20 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01820 d843c9323f53dc609138d69469408f8a 430 Pfam PF07690 Major Facilitator Superfamily 236 419 5.9E-10 T 06-07-2017 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CAL12_RS01820 d843c9323f53dc609138d69469408f8a 430 Gene3D G3DSA:1.20.1250.20 23 198 3.2E-22 T 06-07-2017 CAL12_RS01820 d843c9323f53dc609138d69469408f8a 430 Gene3D G3DSA:1.20.1250.20 226 424 7.0E-17 T 06-07-2017 CAL12_RS01820 d843c9323f53dc609138d69469408f8a 430 SUPERFAMILY SSF103473 13 425 5.23E-48 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS12260 9007dadeeb2866c5c18c219823833f21 230 Pfam PF01988 VIT family 15 223 7.0E-55 T 06-07-2017 IPR008217 Ccc1 family CAL12_RS11480 af96c39aba4cfe93f383c6c6f1bdb32f 288 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 218 285 5.3E-8 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS21365 6b044afd93616326acd05df2188bc1f6 295 Pfam PF01522 Polysaccharide deacetylase 57 168 2.6E-12 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS21365 6b044afd93616326acd05df2188bc1f6 295 Gene3D G3DSA:3.20.20.370 2 278 1.2E-66 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS21365 6b044afd93616326acd05df2188bc1f6 295 SUPERFAMILY SSF88713 2 278 1.4E-63 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS14925 e9bf787408c9b818f8a5188501b5deee 480 Pfam PF03916 Polysulphide reductase, NrfD 78 398 1.6E-21 T 06-07-2017 IPR005614 NrfD family CAL12_RS01000 6399d589d8ca4d9956c08f84cb2de767 72 Pfam PF11174 Protein of unknown function (DUF2970) 14 68 4.7E-21 T 06-07-2017 IPR021344 Protein of unknown function DUF2970 CAL12_RS19465 34cc8804771fb9047e51aa635908f718 298 Pfam PF04909 Amidohydrolase 24 295 1.3E-27 T 06-07-2017 IPR006680 Amidohydrolase-related GO:0016787 CAL12_RS19465 34cc8804771fb9047e51aa635908f718 298 Gene3D G3DSA:3.20.20.140 4 296 2.3E-89 T 06-07-2017 CAL12_RS19465 34cc8804771fb9047e51aa635908f718 298 SUPERFAMILY SSF51556 20 295 1.15E-67 T 06-07-2017 IPR032466 Metal-dependent hydrolase CAL12_RS06425 50a4b0a69e227503c2454b461f407b14 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 324 1.0E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06425 50a4b0a69e227503c2454b461f407b14 327 PIRSF PIRSF017082 1 326 1.9E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS07045 4f8c7aed0d88b8e5436977ef3b47d3ac 430 Pfam PF13379 NMT1-like family 55 305 8.9E-106 T 06-07-2017 CAL12_RS07045 4f8c7aed0d88b8e5436977ef3b47d3ac 430 Gene3D G3DSA:3.40.190.10 184 282 1.4E-6 T 06-07-2017 CAL12_RS07045 4f8c7aed0d88b8e5436977ef3b47d3ac 430 SUPERFAMILY SSF53850 58 296 3.41E-28 T 06-07-2017 CAL12_RS02615 46a19fa724c37afeeb4e320c4f1b52ce 1215 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 867 1209 7.7E-39 T 06-07-2017 IPR007452 Translocation and assembly module TamB CAL12_RS07675 314886f5e8bbe28a9a2ffcde09f47824 324 Pfam PF14336 Domain of unknown function (DUF4392) 30 309 3.3E-49 T 06-07-2017 IPR025504 Domain of unknown function DUF4392 CAL12_RS04225 bb96986e8bedc3c3baba3d7a14b49863 110 Pfam PF13663 Domain of unknown function (DUF4148) 6 65 2.0E-11 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS18200 891db3e1b9e1b0f9de5582d4deaafb4a 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 7 122 18.15 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAL12_RS18200 891db3e1b9e1b0f9de5582d4deaafb4a 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 9 117 1.6E-22 T 06-07-2017 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CAL12_RS02735 978e16ea00068e8bf52134f687599113 429 PIRSF PIRSF006066 1 428 7.4E-137 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS02735 978e16ea00068e8bf52134f687599113 429 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 3.0E-119 T 06-07-2017 IPR004681 TRAP transporter permease protein GO:0016021 CAL12_RS02735 978e16ea00068e8bf52134f687599113 429 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 8 416 3.4E-102 T 06-07-2017 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CAL12_RS16185 99092a36209c95374dcde426fcb60825 689 Pfam PF04632 Fusaric acid resistance protein family 10 667 9.5E-186 T 06-07-2017 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 CAL12_RS15655 de79ff67702fff1eeb770c97ce2d979b 227 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 147 1.3E-40 T 06-07-2017 IPR010419 Carbon monoxide dehydrogenase subunit G CAL12_RS15655 de79ff67702fff1eeb770c97ce2d979b 227 Gene3D G3DSA:3.30.530.20 1 152 2.1E-59 T 06-07-2017 IPR023393 START-like domain CAL12_RS15655 de79ff67702fff1eeb770c97ce2d979b 227 SUPERFAMILY SSF55961 1 146 4.55E-44 T 06-07-2017 CAL12_RS07885 e7b73ccd2622f79cce04506243454f84 748 SUPERFAMILY SSF89550 310 499 1.73E-7 T 06-07-2017 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CAL12_RS11345 dc56962dc0164d1b524c04e4f9d72406 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 1.1E-30 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS11315 66a567fcab857e647e4bc444c53235cc 132 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 33 132 1.3E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS00410 cba5bdadf5c480922126a85d6b12650c 102 Pfam PF13453 Transcription factor zinc-finger 2 43 2.1E-21 T 06-07-2017 IPR027392 Transcription factor zinc-finger CAL12_RS27455 1696a819032db67691718f902f1c8e41 446 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 155 444 4.8E-73 T 06-07-2017 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CAL12_RS27455 1696a819032db67691718f902f1c8e41 446 Pfam PF01578 Cytochrome C assembly protein 184 441 1.1E-41 T 06-07-2017 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CAL12_RS16360 5f31882e94356e6012be182a7346c005 318 SUPERFAMILY SSF53850 88 280 3.8E-11 T 06-07-2017 CAL12_RS16360 5f31882e94356e6012be182a7346c005 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 312 3.0E-79 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS16360 5f31882e94356e6012be182a7346c005 318 PIRSF PIRSF017082 1 317 1.5E-74 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS27075 9158bd9bb29cb070da79d9f48d057c90 421 Pfam PF07399 Putative Na+/H+ antiporter 5 419 1.1E-182 T 06-07-2017 IPR009978 Putative Na+/H+ antiporter CAL12_RS14560 a7664eba6ba970b6445647e2193baad4 476 Gene3D G3DSA:3.30.1330.120 290 422 8.8E-20 T 06-07-2017 CAL12_RS14560 a7664eba6ba970b6445647e2193baad4 476 SUPERFAMILY SSF103378 7 465 2.48E-94 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS14560 a7664eba6ba970b6445647e2193baad4 476 Pfam PF03972 MmgE/PrpD family 9 449 3.3E-90 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS02920 f794edc8290c3cd174c25b042621b478 880 Pfam PF05170 AsmA family 1 210 2.8E-30 T 06-07-2017 IPR007844 AsmA CAL12_RS02920 f794edc8290c3cd174c25b042621b478 880 Pfam PF05170 AsmA family 456 768 5.1E-26 T 06-07-2017 IPR007844 AsmA CAL12_RS01490 08791e61005832e1166ba39fa6afa536 74 Pfam PF11455 Protein of unknown function (DUF3018) 7 72 5.2E-28 T 06-07-2017 IPR021558 Protein of unknown function DUF3018 CAL12_RS02815 7a6ad5eb842d5bfaa490c98328525f32 255 Pfam PF02517 CAAX protease self-immunity 90 237 5.2E-8 T 06-07-2017 IPR003675 CAAX amino terminal protease GO:0016020 CAL12_RS11420 4abd33ce572ff81b32b19aff147754aa 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 2.8E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS19875 5c4e431467ec0c0cb98a62a7f0e7cba2 175 Pfam PF07681 DoxX 44 137 1.6E-18 T 06-07-2017 IPR032808 DoxX family CAL12_RS17310 356e20f77ca086e60aecb764a23074a8 346 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 176 4.9E-29 T 06-07-2017 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CAL12_RS21000 f77aa8704177da05b71fe273eee5524a 188 Pfam PF13827 Domain of unknown function (DUF4189) 87 181 3.0E-19 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 CAL12_RS07785 eabdbd199ef76ba60bbee425cb15a360 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 251 3.1E-32 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS11520 4db606dd74f41d756652f408747d7535 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 38 134 2.5E-36 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS08820 11f0e512344e0198a37b8900a9b0f723 381 Pfam PF05292 Malonyl-CoA decarboxylase (MCD) 50 355 1.4E-123 T 06-07-2017 IPR007956 Malonyl-CoA decarboxylase GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390918 CAL12_RS17800 45df5c9fd61fff77198f19b27289ac58 216 Pfam PF13590 Domain of unknown function (DUF4136) 38 202 1.9E-27 T 06-07-2017 IPR025411 Domain of unknown function DUF4136 CAL12_RS22915 bde4aaf0cae7b825ea779b19657d6677 359 SUPERFAMILY SSF53850 148 319 1.63E-17 T 06-07-2017 CAL12_RS22915 bde4aaf0cae7b825ea779b19657d6677 359 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 84 355 3.2E-95 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS22915 bde4aaf0cae7b825ea779b19657d6677 359 PIRSF PIRSF017082 30 359 3.7E-83 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS05530 f7bfb7bc1fcb6951f9a1576e5497b602 447 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 435 6.2E-95 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAL12_RS05530 f7bfb7bc1fcb6951f9a1576e5497b602 447 PIRSF PIRSF006446 1 445 4.9E-87 T 06-07-2017 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 CAL12_RS21700 ae6e55262529527e0528d37a6244cafb 390 Pfam PF05762 VWA domain containing CoxE-like protein 185 269 4.2E-9 T 06-07-2017 IPR008912 Uncharacterised protein family CoxE-like CAL12_RS16805 678d0f81ec3fb439defbaab1bdfdee15 161 Pfam PF04224 Protein of unknown function, DUF417 56 147 2.7E-9 T 06-07-2017 IPR007339 Protein of unknown function DUF417 CAL12_RS16100 095b71f7135e8f91777a0212da76a894 275 Gene3D G3DSA:3.20.20.370 5 265 1.7E-56 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS16100 095b71f7135e8f91777a0212da76a894 275 SUPERFAMILY SSF88713 5 265 1.56E-46 T 06-07-2017 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CAL12_RS16100 095b71f7135e8f91777a0212da76a894 275 Pfam PF01522 Polysaccharide deacetylase 45 149 3.6E-17 T 06-07-2017 IPR002509 NodB homology domain GO:0005975|GO:0016810 CAL12_RS10970 65eb5e13fc16854d2bab39c57e1f7b14 254 Pfam PF05742 Transport and Golgi organisation 2 1 236 5.4E-59 T 06-07-2017 IPR008551 Transport and Golgi organisation protein 2 CAL12_RS11405 efa895fbee410b2728ed0869b266484c 133 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 133 2.8E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS15190 f824a10038222644f2613953ca0de1ff 366 SUPERFAMILY SSF51412 5 77 1.24E-58 T 06-07-2017 CAL12_RS15190 f824a10038222644f2613953ca0de1ff 366 SUPERFAMILY SSF51412 107 356 1.24E-58 T 06-07-2017 CAL12_RS15190 f824a10038222644f2613953ca0de1ff 366 Pfam PF03060 Nitronate monooxygenase 8 350 2.1E-79 T 06-07-2017 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CAL12_RS15190 f824a10038222644f2613953ca0de1ff 366 Gene3D G3DSA:3.20.20.70 4 344 7.5E-66 T 06-07-2017 IPR013785 Aldolase-type TIM barrel GO:0003824 CAL12_RS19385 b52805a6aa59f8cc7170cb7be76287df 188 Pfam PF03729 Short repeat of unknown function (DUF308) 14 78 7.4E-9 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAL12_RS19385 b52805a6aa59f8cc7170cb7be76287df 188 Pfam PF03729 Short repeat of unknown function (DUF308) 132 179 8.0E-6 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAL12_RS19385 b52805a6aa59f8cc7170cb7be76287df 188 Pfam PF03729 Short repeat of unknown function (DUF308) 74 141 3.6E-13 T 06-07-2017 IPR005325 Protein of unknown function DUF308, membrane CAL12_RS08120 4e7ecb3b9f1587343a9df7cabaecfe3c 594 Pfam PF15984 Bacterial collagen, middle region 142 250 6.3E-14 T 06-07-2017 IPR031929 Bacterial collagen-like protein, middle domain CAL12_RS08120 4e7ecb3b9f1587343a9df7cabaecfe3c 594 Pfam PF15984 Bacterial collagen, middle region 260 411 4.4E-9 T 06-07-2017 IPR031929 Bacterial collagen-like protein, middle domain CAL12_RS20245 b85902e999e6da2402049f96a262eb08 288 Pfam PF03524 Conjugal transfer protein 37 260 2.9E-52 T 06-07-2017 IPR010258 Conjugal transfer, TrbG/VirB9/CagX CAL12_RS19890 6debea4d8b3755976cf263aeb5f235db 213 Pfam PF06532 Protein of unknown function (DUF1109) 10 213 2.1E-64 T 06-07-2017 IPR009495 Protein of unknown function DUF1109 CAL12_RS02320 486eb758d3cada4b291c842817212054 357 Gene3D G3DSA:3.20.20.410 52 352 2.4E-59 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS02320 486eb758d3cada4b291c842817212054 357 Pfam PF01904 Protein of unknown function DUF72 82 350 3.3E-38 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS02320 486eb758d3cada4b291c842817212054 357 SUPERFAMILY SSF117396 60 352 1.7E-44 T 06-07-2017 IPR002763 Protein of unknown function DUF72 CAL12_RS23335 89a819117ba7ee016487e1d1e656e902 334 SUPERFAMILY SSF53850 27 248 2.55E-26 T 06-07-2017 CAL12_RS23335 89a819117ba7ee016487e1d1e656e902 334 Pfam PF13379 NMT1-like family 23 252 4.3E-26 T 06-07-2017 CAL12_RS23335 89a819117ba7ee016487e1d1e656e902 334 Gene3D G3DSA:3.40.190.10 138 243 6.4E-10 T 06-07-2017 CAL12_RS20380 da1051c6407271ec2b010c299b2fa1aa 151 Pfam PF11154 Protein of unknown function (DUF2934) 117 144 6.4E-9 T 06-07-2017 IPR021327 Protein of unknown function DUF2934 CAL12_RS20380 da1051c6407271ec2b010c299b2fa1aa 151 Pfam PF11154 Protein of unknown function (DUF2934) 86 118 1.9E-10 T 06-07-2017 IPR021327 Protein of unknown function DUF2934 CAL12_RS21880 886ecd96c4ec134b84b61cbc72326ccb 307 SUPERFAMILY SSF51621 13 305 7.18E-74 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS21880 886ecd96c4ec134b84b61cbc72326ccb 307 Pfam PF13714 Phosphoenolpyruvate phosphomutase 30 269 1.9E-52 T 06-07-2017 CAL12_RS21880 886ecd96c4ec134b84b61cbc72326ccb 307 Gene3D G3DSA:3.20.20.60 19 304 3.6E-75 T 06-07-2017 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CAL12_RS14900 bdab3d0d86b5ff53235a4086c28fa219 268 SUPERFAMILY SSF52833 52 199 3.8E-19 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS14900 bdab3d0d86b5ff53235a4086c28fa219 268 Gene3D G3DSA:3.40.30.10 52 196 6.3E-21 T 06-07-2017 IPR012336 Thioredoxin-like fold CAL12_RS12270 53b4e33c40f18a7e66607de212d5ee12 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 2.2E-50 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS20280 b7d8c5814480293c7f040873fda6b2d6 129 Gene3D G3DSA:1.20.1410.10 31 100 5.2E-4 T 06-07-2017 IPR002558 I/LWEQ domain GO:0003779 CAL12_RS12690 a487273d894502e8c9f7e93a86dca1f8 170 Pfam PF07813 LTXXQ motif family protein 54 145 1.3E-7 T 06-07-2017 IPR012899 LTXXQ motif family protein GO:0042597 CAL12_RS04215 6af7ff2d567153eeee3c0a7ed11e41f4 339 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 43 323 6.2E-44 T 06-07-2017 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CAL12_RS08510 2eba4d2aa6ebfcbac0fbf780cafff212 459 SUPERFAMILY SSF103473 48 447 8.11E-42 T 06-07-2017 IPR020846 Major facilitator superfamily domain CAL12_RS08510 2eba4d2aa6ebfcbac0fbf780cafff212 459 Gene3D G3DSA:1.20.1250.20 60 250 2.8E-9 T 06-07-2017 CAL12_RS08510 2eba4d2aa6ebfcbac0fbf780cafff212 459 Gene3D G3DSA:1.20.1250.20 273 448 7.8E-24 T 06-07-2017 CAL12_RS08510 2eba4d2aa6ebfcbac0fbf780cafff212 459 Pfam PF11700 Vacuole effluxer Atg22 like 93 457 9.0E-35 T 06-07-2017 IPR024671 Autophagy-related protein 22-like CAL12_RS04550 fa26f7a0d0a9ede6247e8e928d4837e1 343 SUPERFAMILY SSF51445 38 115 5.55E-6 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS04550 fa26f7a0d0a9ede6247e8e928d4837e1 343 SUPERFAMILY SSF51445 146 246 5.55E-6 T 06-07-2017 IPR017853 Glycoside hydrolase superfamily CAL12_RS27300 161d67cbb96637b591b666fdef8f154b 507 Pfam PF14264 Glucosyl transferase GtrII 27 335 4.5E-35 T 06-07-2017 IPR025686 Glucosyl transferase II CAL12_RS04710 96ddb17f22698a9bbc0eded7865e7bfa 458 Pfam PF03972 MmgE/PrpD family 17 441 1.1E-125 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS04710 96ddb17f22698a9bbc0eded7865e7bfa 458 Gene3D G3DSA:3.30.1330.120 276 394 4.6E-22 T 06-07-2017 CAL12_RS04710 96ddb17f22698a9bbc0eded7865e7bfa 458 SUPERFAMILY SSF103378 14 448 6.93E-120 T 06-07-2017 IPR005656 MmgE/PrpD GO:0016829 CAL12_RS22770 340c7d4f35b9946a130cbd0d2ae1a95a 205 Pfam PF01339 CheB methylesterase 15 188 2.3E-54 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS22770 340c7d4f35b9946a130cbd0d2ae1a95a 205 SUPERFAMILY SSF52738 10 197 2.88E-56 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS22770 340c7d4f35b9946a130cbd0d2ae1a95a 205 Gene3D G3DSA:3.40.50.180 9 196 1.6E-62 T 06-07-2017 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CAL12_RS13925 f734482dc1f17e9cceea6c3d3b294df8 137 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 12 84 4.1E-12 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS17435 886396b5a7ede114ef742818d5c061b0 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 186 7.0E-30 T 06-07-2017 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CAL12_RS19775 0f0ba796ea646d0e6a25f852171ce4aa 492 Pfam PF03929 PepSY-associated TM region 30 421 5.6E-53 T 06-07-2017 IPR005625 PepSY-associated TM protein CAL12_RS13320 58424763afedabb39f7f89dadeed3833 337 Gene3D G3DSA:3.40.190.10 139 250 7.3E-4 T 06-07-2017 CAL12_RS13320 58424763afedabb39f7f89dadeed3833 337 SUPERFAMILY SSF53850 126 296 9.31E-11 T 06-07-2017 CAL12_RS13320 58424763afedabb39f7f89dadeed3833 337 PIRSF PIRSF017082 3 335 2.4E-78 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS13320 58424763afedabb39f7f89dadeed3833 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 58 330 1.1E-67 T 06-07-2017 IPR005064 Bordetella uptake gene GO:0030288 CAL12_RS06650 b7f0f4625d60b08ca25d4261b7589b8b 190 Pfam PF01475 Ferric uptake regulator family 54 168 7.7E-8 T 06-07-2017 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CAL12_RS06650 b7f0f4625d60b08ca25d4261b7589b8b 190 Gene3D G3DSA:1.10.10.10 46 123 1.3E-10 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS06650 b7f0f4625d60b08ca25d4261b7589b8b 190 SUPERFAMILY SSF46785 47 169 5.84E-13 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 SUPERFAMILY SSF46626 223 246 7.71E-48 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 SUPERFAMILY SSF46626 18 167 7.71E-48 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 Pfam PF02167 Cytochrome C1 family 227 280 1.6E-6 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 Pfam PF02167 Cytochrome C1 family 36 141 4.3E-9 T 06-07-2017 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 Gene3D G3DSA:1.10.760.10 223 247 5.4E-61 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00750 d761daa2de2e95fd3352c288a4d90605 282 Gene3D G3DSA:1.10.760.10 18 191 5.4E-61 T 06-07-2017 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CAL12_RS00925 61ca381f7ac4535d05cebebfaa41735c 241 SUPERFAMILY SSF143422 38 109 1.2E-5 T 06-07-2017 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 CAL12_RS20975 236d2c06abbfb03041c85ee5bed2bbe5 700 Pfam PF01968 Hydantoinase/oxoprolinase 206 501 1.0E-81 T 06-07-2017 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS20975 236d2c06abbfb03041c85ee5bed2bbe5 700 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 184 1.3E-48 T 06-07-2017 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS03690 d0b8a499d33bd4804cf59297f524b507 343 Pfam PF14336 Domain of unknown function (DUF4392) 53 321 1.2E-67 T 06-07-2017 IPR025504 Domain of unknown function DUF4392 CAL12_RS01255 52c3638d218065a3e31af96a4ad1cc84 123 Pfam PF04248 Domain of unknown function (DUF427) 23 114 1.2E-31 T 06-07-2017 IPR007361 Domain of unknown function DUF427 CAL12_RS21295 69f8faa5aee4a5c03f1c9605d3e9919b 294 Pfam PF02104 SURF1 family 52 272 1.1E-42 T 06-07-2017 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CAL12_RS12840 e1fc79de527ecdb0f460feebb145afef 171 Pfam PF00866 Ring hydroxylating beta subunit 34 163 1.6E-13 T 06-07-2017 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CAL12_RS12840 e1fc79de527ecdb0f460feebb145afef 171 Gene3D G3DSA:3.10.450.50 17 165 4.1E-31 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS12840 e1fc79de527ecdb0f460feebb145afef 171 SUPERFAMILY SSF54427 17 170 2.37E-42 T 06-07-2017 IPR032710 NTF2-like domain CAL12_RS09450 a55438c009380bb0889c18804d1547c3 72 Pfam PF11381 Protein of unknown function (DUF3185) 7 65 1.0E-4 T 06-07-2017 IPR021521 Protein of unknown function DUF3185 CAL12_RS13745 b62687b697d849380e29881a96316ab2 210 Pfam PF03596 Cadmium resistance transporter 17 208 6.8E-10 T 06-07-2017 IPR004676 Cadmium resistance transporter CAL12_RS12615 779b1b954ec86bd91a5364a696cf0534 253 Pfam PF01925 Sulfite exporter TauE/SafE 20 249 1.1E-22 T 06-07-2017 IPR002781 Transmembrane protein TauE-like GO:0016021 CAL12_RS23350 482b313ca76fb61e31c038d0c7136973 243 PIRSF PIRSF015736 1 243 8.4E-62 T 06-07-2017 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CAL12_RS08505 86cd2eeb04511ae9e593e6163aa2c711 135 Pfam PF03928 Haem-degrading 7 130 2.2E-32 T 06-07-2017 IPR005624 Haem-degrading CAL12_RS08505 86cd2eeb04511ae9e593e6163aa2c711 135 SUPERFAMILY SSF143744 2 134 1.83E-36 T 06-07-2017 CAL12_RS11295 c37805795f652529872634a6fea44d96 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 2.7E-31 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS00265 bb4de56d4ba3a0f0b53ead16972b7e87 237 Pfam PF11182 Alginate O-acetyl transferase AlgF 18 185 5.1E-9 T 06-07-2017 CAL12_RS11525 11729f08592b6e75fc1d58f9b4208114 155 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 59 155 5.6E-32 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS07640 5d448c85d2b31f869954df938f5621c8 96 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 45 1.7E-8 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS07640 5d448c85d2b31f869954df938f5621c8 96 SUPERFAMILY SSF143120 1 44 6.15E-8 T 06-07-2017 CAL12_RS07640 5d448c85d2b31f869954df938f5621c8 96 Gene3D G3DSA:3.40.1620.10 1 43 6.1E-7 T 06-07-2017 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CAL12_RS00370 40a466be4fd5e22752009e95f5a14746 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 269 2.0E-25 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS07400 730945cee06468ab14054fe08478cc5a 383 Pfam PF06804 NlpB/DapX lipoprotein 41 377 3.9E-46 T 06-07-2017 IPR010653 NlpB/DapX lipoprotein CAL12_RS22950 027df1fe5993b2795c9672ab3da5ffd1 472 Pfam PF07394 Protein of unknown function (DUF1501) 58 447 2.7E-47 T 06-07-2017 IPR010869 Protein of unknown function DUF1501 CAL12_RS20055 8b72f4bb9e48cf59a2144e1b85e8dc22 103 Pfam PF09413 Putative prokaryotic signal transducing protein 2 65 1.2E-9 T 06-07-2017 IPR018551 Domain of unknown function DUF2007 CAL12_RS25245 b41267d0b37162133e969a725a0fe264 396 SUPERFAMILY SSF161098 184 376 1.7E-42 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25245 b41267d0b37162133e969a725a0fe264 396 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 186 282 1.8E-18 T 06-07-2017 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CAL12_RS25245 b41267d0b37162133e969a725a0fe264 396 Gene3D G3DSA:1.10.3720.10 184 391 3.0E-46 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS25245 b41267d0b37162133e969a725a0fe264 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 204 391 6.2E-22 T 06-07-2017 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CAL12_RS06630 c786a81d4c3fe42ff441b560823c7cd8 165 Pfam PF13827 Domain of unknown function (DUF4189) 65 158 1.2E-23 T 06-07-2017 IPR025240 Domain of unknown function DUF4189 CAL12_RS01545 b3ba6e5693acd8d844f72438e9e41e90 267 Pfam PF05275 Copper resistance protein B precursor (CopB) 63 267 1.2E-77 T 06-07-2017 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 CAL12_RS08735 fbd77e3f30ac7855b5706318b9e4f53e 81 Pfam PF10685 Stress-induced bacterial acidophilic repeat motif 15 36 2.5E-7 T 06-07-2017 IPR019626 Stress-induced protein, KGG, repeat CAL12_RS24380 05d51de0f59cb3501208d80e392fc776 343 Pfam PF06224 Winged helix DNA-binding domain 3 339 1.4E-67 T 06-07-2017 IPR009351 Protein of unknown function DUF1006 CAL12_RS26855 9c77e833c59da3d6eaf4484acddf2714 301 Pfam PF13489 Methyltransferase domain 89 246 1.5E-26 T 06-07-2017 CAL12_RS26855 9c77e833c59da3d6eaf4484acddf2714 301 Gene3D G3DSA:3.40.50.150 95 269 2.1E-32 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS26855 9c77e833c59da3d6eaf4484acddf2714 301 SUPERFAMILY SSF53335 95 280 2.43E-36 T 06-07-2017 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CAL12_RS01010 6bfbad193e6b5653c22335505f76f352 66 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 2.0E-25 T 06-07-2017 IPR021313 Protein of unknown function DUF2909 CAL12_RS04480 74f4a951a79e7a3d72510814165dd525 319 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 20 290 4.2E-54 T 06-07-2017 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 CAL12_RS01090 fd97bd314af5c32dd263fb01e3807064 456 Pfam PF13191 AAA ATPase domain 32 188 4.4E-9 T 06-07-2017 CAL12_RS01090 fd97bd314af5c32dd263fb01e3807064 456 Gene3D G3DSA:3.40.50.300 25 211 4.3E-15 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01090 fd97bd314af5c32dd263fb01e3807064 456 SUPERFAMILY SSF52540 140 281 1.87E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS01090 fd97bd314af5c32dd263fb01e3807064 456 SUPERFAMILY SSF52540 27 100 1.87E-21 T 06-07-2017 IPR027417 P-loop containing nucleoside triphosphate hydrolase CAL12_RS04965 5a9ba07eea36124a4cc70cc777a9c013 152 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 118 1.1E-17 T 06-07-2017 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CAL12_RS01960 10c6ab54c6445764ac23964e3c83dfb9 191 Pfam PF04366 Las17-binding protein actin regulator 104 188 5.7E-14 T 06-07-2017 IPR007461 Ysc84 actin-binding domain CAL12_RS01815 08ec59ba18286e33f586f45efb80db41 224 Pfam PF08892 YqcI/YcgG family 10 211 8.6E-68 T 06-07-2017 IPR014988 Uncharacterised protein family, YqcI/YcgG CAL12_RS17090 9d4ce34c09dca9dc1c8c81992521db27 114 Pfam PF13663 Domain of unknown function (DUF4148) 1 67 2.2E-10 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS11365 097be8aac71a906f56f29df9c390ab5e 129 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 31 129 7.0E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS20125 4e82993481d9842ba3bb5eb160c68750 724 Pfam PF02538 Hydantoinase B/oxoprolinase 178 694 1.8E-138 T 06-07-2017 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 CAL12_RS02165 e70d0c3936336e8fa948d8b325788817 302 SUPERFAMILY SSF53474 30 268 2.34E-49 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02165 e70d0c3936336e8fa948d8b325788817 302 Gene3D G3DSA:3.40.50.1820 47 292 1.4E-61 T 06-07-2017 IPR029058 Alpha/Beta hydrolase fold CAL12_RS02165 e70d0c3936336e8fa948d8b325788817 302 Pfam PF07859 alpha/beta hydrolase fold 76 165 6.2E-16 T 06-07-2017 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CAL12_RS05070 412be365e38eae2cb04ca3af673c2fa3 364 Pfam PF01757 Acyltransferase family 3 335 1.3E-15 T 06-07-2017 IPR002656 Acyltransferase 3 GO:0016747 CAL12_RS12330 eb270f87f1394303e3813f2fc4022ac7 152 SUPERFAMILY SSF46785 11 145 2.98E-37 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12330 eb270f87f1394303e3813f2fc4022ac7 152 Gene3D G3DSA:1.10.10.10 8 113 1.0E-31 T 06-07-2017 IPR011991 Winged helix-turn-helix DNA-binding domain CAL12_RS12330 eb270f87f1394303e3813f2fc4022ac7 152 Pfam PF01638 HxlR-like helix-turn-helix 24 109 2.3E-21 T 06-07-2017 IPR002577 Helix-turn-helix, HxlR type CAL12_RS07255 c8644b4af6e3ee87fd87dfba20b68e07 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 295 1.0E-29 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS07390 152bc7e3a92afccf816963ed42cc46ef 215 Pfam PF02163 Peptidase family M50 129 192 1.4E-6 T 06-07-2017 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 CAL12_RS13140 6cb6e604b2ac30854cd8d3e70246b4f3 257 Pfam PF11828 Protein of unknown function (DUF3348) 1 245 3.7E-91 T 06-07-2017 IPR021783 Protein of unknown function DUF3348 CAL12_RS04910 8766ac14ff4d12c32bd20b773653796d 129 Gene3D G3DSA:1.20.5.170 22 72 5.1E-4 T 06-07-2017 CAL12_RS01025 d086bfa372cc2c2c9c53028086d64b8d 347 Pfam PF02628 Cytochrome oxidase assembly protein 10 320 2.0E-79 T 06-07-2017 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CAL12_RS21360 0770d89160120b5be1b69b853ea17f2a 40 Pfam PF10617 Protein of unknown function (DUF2474) 2 38 1.3E-12 T 06-07-2017 IPR018895 Protein of unknown function DUF2474 CAL12_RS11415 81e6164540eeee54efcdcb488b9002db 134 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 35 134 1.7E-33 T 06-07-2017 IPR010221 VCBS repeat CAL12_RS17515 57963e7bb9dca38dc2f1e69e2562e5eb 134 Pfam PF12112 Protein of unknown function (DUF3579) 38 127 3.3E-35 T 06-07-2017 IPR021969 Protein of unknown function DUF3579 CAL12_RS24840 9c7f07f8ea6f4889f6a9c2c8a7a00dbc 186 Pfam PF02325 YGGT family 12 80 3.3E-17 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 CAL12_RS24840 9c7f07f8ea6f4889f6a9c2c8a7a00dbc 186 Pfam PF02325 YGGT family 110 175 3.1E-15 T 06-07-2017 IPR003425 CCB3/YggT GO:0016020 CAL12_RS27370 388dc5216484029219249367ea6604b5 200 Pfam PF12385 Papain-like cysteine protease AvrRpt2 42 171 7.5E-6 T 06-07-2017 IPR022118 Peptidase C70, AvrRpt2 CAL12_RS22140 5b6518a707ad8754ce48e57f86a996a6 493 TIGRFAM TIGR02500 type_III_yscD: type III secretion apparatus protein, YscD/HrpQ family 14 487 9.2E-38 T 06-07-2017 IPR012843 Type III secretion system YscD/HrpQ CAL12_RS00965 b373b1d13dd127f47679decd41661afd 152 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 8 133 3.1E-27 T 06-07-2017 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component CAL12_RS12420 fcbb79852c08a71522d607e58b162773 193 Pfam PF02417 Chromate transporter 23 179 6.2E-31 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS23885 e84110c8b49732e3e4e047b6c5f59e78 110 Pfam PF13663 Domain of unknown function (DUF4148) 1 67 1.4E-10 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS12425 bec5e1ddf53fd3c8438caffccb828d0d 177 Pfam PF02417 Chromate transporter 7 169 8.3E-36 T 06-07-2017 IPR003370 Chromate transporter GO:0015109|GO:0015703 CAL12_RS12425 bec5e1ddf53fd3c8438caffccb828d0d 177 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 18 32 - T 06-07-2017 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CAL12_RS13350 123159b970618d88c2db4a99cdb79ed2 305 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 281 1.6E-47 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS26960 bde357aac865ef24109944a11cc681e0 131 Pfam PF04138 GtrA-like protein 11 130 2.1E-21 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAL12_RS21210 dc257a4838850b3850c63483f17556b1 102 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 13 95 2.3E-29 T 06-07-2017 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CAL12_RS02190 f6a517d156f7c13b94791d63cfc16b82 107 TIGRFAM TIGR03976 chp_LLNDYxLRE: His-Xaa-Ser system protein HxsD 5 95 3.2E-16 T 06-07-2017 IPR023974 His-Xaa-Ser system protein HxsD CAL12_RS16110 39846636892aa733ad86ad701e64f4bf 377 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 131 328 1.5E-8 T 06-07-2017 IPR005079 Peptidase C45 CAL12_RS03585 c54dc495375735c331b1b9c90fd63b8f 248 Pfam PF03741 Integral membrane protein TerC family 19 209 6.5E-51 T 06-07-2017 IPR005496 Integral membrane protein TerC GO:0016021 CAL12_RS05620 f6cd7532a9f67810b04502624af6fe10 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 287 1.8E-34 T 06-07-2017 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CAL12_RS15735 8c9d901927710c2954f0de4d71336340 70 Pfam PF06348 Protein of unknown function (DUF1059) 4 58 2.1E-12 T 06-07-2017 IPR009409 Protein of unknown function DUF1059 CAL12_RS05195 658ff2ed0d9fdc45300bdb24f17557a1 144 Gene3D G3DSA:3.90.650.10 78 126 5.5E-5 T 06-07-2017 IPR010918 AIR synthase-related protein, C-terminal domain CAL12_RS01825 abda95c79730fb7a32e622b06416f3c5 239 SUPERFAMILY SSF55729 57 136 1.14E-5 T 06-07-2017 IPR016181 Acyl-CoA N-acyltransferase CAL12_RS27365 361cd17fbf73504ab22a145b1e88044b 106 Pfam PF03860 Domain of Unknown Function (DUF326) 85 100 2.8E-4 T 06-07-2017 IPR005560 Protein of unknown function DUF326 CAL12_RS18560 5b6256e1fe377d341d88d377ff4070f2 260 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 64 218 2.7E-32 T 06-07-2017 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 CAL12_RS04460 8ed2571f2f12480a93486ebab2b154d0 161 Pfam PF09722 Protein of unknown function (DUF2384) 116 158 8.2E-13 T 06-07-2017 IPR024467 Domain of unknown function DUF2384 CAL12_RS22955 8d2df4fa68b2993214dee1a88c95d6c0 524 Pfam PF08811 Protein of unknown function (DUF1800) 30 521 5.0E-85 T 06-07-2017 IPR014917 Protein of unknown function DUF1800 CAL12_RS08595 bd3878e50ae0bda8e8b2d094ed59fc2e 336 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 32 309 3.3E-13 T 06-07-2017 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CAL12_RS05065 1237f937777fb6ad983d355763cdedf1 499 Pfam PF00474 Sodium:solute symporter family 46 422 1.8E-22 T 06-07-2017 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CAL12_RS08440 749a7550ce22328d6b10ff937d927b2c 237 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 26 228 4.1E-41 T 06-07-2017 CAL12_RS16335 364d62f4c4835b2726208cb43dff8b7f 102 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 4 102 3.7E-37 T 06-07-2017 IPR018678 Protein of unknown function DUF2160, transmembrane CAL12_RS23600 1906599dd66b6bd67a42764beaa11c44 234 Pfam PF10707 PhoP regulatory network protein YrbL 34 213 1.4E-25 T 06-07-2017 IPR019647 PhoP regulatory network protein YrbL CAL12_RS02835 85aa71ad4ebce2199bf903dbd847a72d 270 Pfam PF06250 Protein of unknown function (DUF1016) 20 210 7.5E-62 T 06-07-2017 IPR009362 Protein of unknown function DUF1016 CAL12_RS26940 12402d9fda587df76b594cf0b95823da 127 Pfam PF04138 GtrA-like protein 7 116 1.5E-13 T 06-07-2017 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CAL12_RS00040 6755c589e59d473ad7b36d331bc8e839 122 Pfam PF13663 Domain of unknown function (DUF4148) 15 83 1.2E-9 T 06-07-2017 IPR025421 Protein of unknown function DUF4148 CAL12_RS00665 8ab225adaccc14e9b645616ed9a83995 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 5.7E-11 T 06-07-2017 IPR007419 BFD-like [2Fe-2S]-binding domain CAL12_RS20895 16cdbb44685750d9fe4c1e5708c001c0 213 Pfam PF13470 PIN domain 5 107 5.3E-9 T 06-07-2017 IPR002716 PIN domain CAL12_RS25520 8c6ee047b0c078cfc38c3bab21a58aba 233 Pfam PF09347 Domain of unknown function (DUF1989) 40 204 5.2E-58 T 06-07-2017 IPR018959 Domain of unknown function DUF1989 CAL12_RS08525 8a6749890e100d4bfb7f2e5d3db321fe 240 Pfam PF04536 Acid phosphatase of thylakoid lumen protein 17 138 6.2E-40 T 06-07-2017 IPR007621 TPM domain CAL12_RS21680 b9886ac5f647beffc8688496f1acf54c 141 Pfam PF08897 Domain of unknown function (DUF1841) 5 136 1.1E-57 T 06-07-2017 IPR014993 Protein of unknown function DUF1841 CAL12_RS16190 8a1df2a774fc3b2c33d6f19daed12dd8 72 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 2.3E-21 T 06-07-2017 IPR012451 Protein of unknown function DUF1656 CAL12_RS08685 f5ddb113c07254ce98cdd9c86f6859fb 178 Pfam PF06271 RDD family 11 157 2.6E-17 T 06-07-2017 IPR010432 RDD