locus-tag	class	description
CAL14_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAL14_RS00020	COG0583	DNA-binding transcription factor activity
CAL14_RS00030	COG2175	clavaminate synthase activity
CAL14_RS00075	COG1573	uracil-dna glycosylase
CAL14_RS00100	COG0657	acetylesterase activity
CAL14_RS00115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL14_RS00130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAL14_RS00140	COG1522	sequence-specific DNA binding
CAL14_RS00145	COG0028	Belongs to the TPP enzyme family
CAL14_RS00150	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS00155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAL14_RS00155	COG0551	DNA topoisomerase type I activity
CAL14_RS00165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL14_RS00170	COG2922	Belongs to the Smg family
CAL14_RS00180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAL14_RS00195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAL14_RS00200	COG0183	Belongs to the thiolase family
CAL14_RS00205	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS00215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL14_RS00220	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS00240	COG0018	arginyl-trna synthetase
CAL14_RS00260	COG0154	amidase activity
CAL14_RS00265	COG1609	Transcriptional regulator
CAL14_RS00270	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL14_RS00280	COG1177	transmembrane transport
CAL14_RS00285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL14_RS00290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL14_RS00300	COG1653	transport
CAL14_RS00305	COG1175	transmembrane transport
CAL14_RS00310	COG0395	ABC-type sugar transport system, permease component
CAL14_RS00315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL14_RS00325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL14_RS00350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CAL14_RS00355	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS00360	COG0513	Belongs to the DEAD box helicase family
CAL14_RS00405	COG0625	glutathione transferase activity
CAL14_RS00410	COG2857	Cytochrome c1
CAL14_RS00415	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAL14_RS00420	COG0723	plastoquinol--plastocyanin reductase activity
CAL14_RS00425	COG1970	mechanosensitive ion channel activity
CAL14_RS00430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAL14_RS00435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL14_RS00450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL14_RS00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL14_RS00460	COG0537	adenosine 5'-monophosphoramidase activity
CAL14_RS00465	COG0140	phosphoribosyl-ATP diphosphatase activity
CAL14_RS00475	COG0107	imidazoleglycerol-phosphate synthase activity
CAL14_RS00480	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAL14_RS00490	COG0131	Imidazoleglycerol-phosphate dehydratase
CAL14_RS00495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL14_RS00500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAL14_RS00505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CAL14_RS00510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAL14_RS00515	COG0271	Belongs to the BolA IbaG family
CAL14_RS00520	COG0842	Transport permease protein
CAL14_RS00525	COG1131	(ABC) transporter
CAL14_RS00535	COG2853	Lipoprotein
CAL14_RS00540	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL14_RS00545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL14_RS00550	COG1127	ABC transporter
CAL14_RS00560	COG2059	Chromate
CAL14_RS00570	COG0067	glutamate synthase
CAL14_RS00570	COG0069	glutamate synthase activity
CAL14_RS00570	COG0070	glutamate synthase
CAL14_RS00600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL14_RS00615	COG0747	negative chemotaxis
CAL14_RS00620	COG1609	Transcriptional regulator
CAL14_RS00625	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL14_RS00630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS00635	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL14_RS00640	COG0129	dihydroxy-acid dehydratase activity
CAL14_RS00645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CAL14_RS00655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL14_RS00695	COG1999	signal sequence binding
CAL14_RS00720	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAL14_RS00725	COG2814	Major facilitator Superfamily
CAL14_RS00740	COG1522	sequence-specific DNA binding
CAL14_RS00770	COG0477	Major facilitator Superfamily
CAL14_RS00785	COG0066	3-isopropylmalate dehydratase activity
CAL14_RS00790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAL14_RS00795	COG2188	Transcriptional regulator
CAL14_RS00805	COG2814	Major facilitator Superfamily
CAL14_RS00810	COG4977	sequence-specific DNA binding
CAL14_RS00815	COG1304	FMN binding
CAL14_RS00820	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS00840	COG1396	sequence-specific DNA binding
CAL14_RS00845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS00850	COG0765	amino acid transport
CAL14_RS00855	COG1126	abc transporter atp-binding protein
CAL14_RS00860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS00865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL14_RS00895	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS00915	COG1414	Transcriptional regulator
CAL14_RS00930	COG2358	TRAP transporter, solute receptor (TAXI family
CAL14_RS00935	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CAL14_RS00940	COG1074	ATP-dependent DNA helicase activity
CAL14_RS00945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAL14_RS00955	COG0784	Response regulator, receiver
CAL14_RS00955	COG4191	Histidine kinase
CAL14_RS00990	COG1666	GTP binding
CAL14_RS01000	COG0300	oxidoreductase activity
CAL14_RS01005	COG2207	Transcriptional regulator
CAL14_RS01010	COG4208	sulfate ABC transporter
CAL14_RS01015	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS01020	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL14_RS01030	COG2816	NAD+ diphosphatase activity
CAL14_RS01035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL14_RS01040	COG2823	Periplasmic or secreted lipoprotein
CAL14_RS01045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CAL14_RS01050	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS01055	COG0792	nuclease activity
CAL14_RS01070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CAL14_RS01075	COG1660	Displays ATPase and GTPase activities
CAL14_RS01090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAL14_RS01100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAL14_RS01105	COG1137	ATPase activity
CAL14_RS01130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CAL14_RS01135	COG0747	negative chemotaxis
CAL14_RS01145	COG1309	transcriptional regulator
CAL14_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL14_RS01165	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAL14_RS01170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAL14_RS01175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAL14_RS01180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAL14_RS01185	COG0142	geranyltranstransferase activity
CAL14_RS01195	COG4106	trans-aconitate 2-methyltransferase activity
CAL14_RS01205	COG3403	YqcI/YcgG family
CAL14_RS01240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL14_RS01250	COG1414	Transcriptional regulator
CAL14_RS01255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CAL14_RS01265	COG0129	dihydroxy-acid dehydratase activity
CAL14_RS01270	COG2814	Major facilitator Superfamily
CAL14_RS01280	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CAL14_RS01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL14_RS01305	COG0583	DNA-binding transcription factor activity
CAL14_RS01320	COG0058	SHG alpha-glucan phosphorylase activity
CAL14_RS01335	COG0420	3'-5' exonuclease activity
CAL14_RS01415	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL14_RS01445	COG0326	Molecular chaperone. Has ATPase activity
CAL14_RS01450	COG1396	sequence-specific DNA binding
CAL14_RS01460	COG2271	Major facilitator Superfamily
CAL14_RS01465	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS01470	COG0800	Aldolase
CAL14_RS01475	COG3734	2-keto-3-deoxy-galactonokinase
CAL14_RS01480	COG1414	Transcriptional regulator
CAL14_RS01500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAL14_RS01515	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CAL14_RS01540	COG1116	anion transmembrane transporter activity
CAL14_RS01545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS01555	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL14_RS01560	COG0583	DNA-binding transcription factor activity
CAL14_RS01565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL14_RS01575	COG0277	FAD linked oxidase domain protein
CAL14_RS01575	COG0247	lactate metabolic process
CAL14_RS01580	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS01590	COG1024	Enoyl-CoA hydratase
CAL14_RS01595	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS01605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL14_RS01630	COG4774	siderophore transport
CAL14_RS01635	COG3712	iron ion homeostasis
CAL14_RS01640	COG1595	DNA-templated transcription, initiation
CAL14_RS01645	COG0625	glutathione transferase activity
CAL14_RS01660	COG2264	protein methyltransferase activity
CAL14_RS01665	COG0531	amino acid
CAL14_RS01700	COG0583	DNA-binding transcription factor activity
CAL14_RS01715	COG1054	Belongs to the UPF0176 family
CAL14_RS01750	COG0717	Belongs to the dCTP deaminase family
CAL14_RS01765	COG2081	HI0933 family
CAL14_RS01775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAL14_RS01780	COG0509	glycine decarboxylation via glycine cleavage system
CAL14_RS01785	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL14_RS01785	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL14_RS01800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL14_RS01805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS01820	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAL14_RS01835	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAL14_RS01850	COG0277	FAD linked oxidase domain protein
CAL14_RS01855	COG0745	RESPONSE REGULATOR receiver
CAL14_RS01870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS01870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL14_RS01880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL14_RS01885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL14_RS01890	COG2186	Transcriptional regulator
CAL14_RS01895	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL14_RS01900	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CAL14_RS01910	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAL14_RS01920	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CAL14_RS01925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CAL14_RS01935	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAL14_RS01945	COG0193	aminoacyl-tRNA hydrolase activity
CAL14_RS01965	COG0012	GTP binding
CAL14_RS01970	COG2814	Major facilitator Superfamily
CAL14_RS01980	COG0842	Transport permease protein
CAL14_RS01985	COG0842	Transport permease protein
CAL14_RS01990	COG1131	(ABC) transporter
CAL14_RS02015	COG3135	benzoate transporter
CAL14_RS02020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAL14_RS02025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAL14_RS02030	COG0742	ribosomal rna small subunit methyltransferase
CAL14_RS02040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAL14_RS02055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAL14_RS02060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL14_RS02065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAL14_RS02075	COG1546	Belongs to the CinA family
CAL14_RS02080	COG0284	orotidine-5'-phosphate decarboxylase activity
CAL14_RS02085	COG1252	NADH dehydrogenase
CAL14_RS02100	COG1063	alcohol dehydrogenase
CAL14_RS02105	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL14_RS02115	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02125	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL14_RS02130	COG2721	sulfolactate sulfo-lyase activity
CAL14_RS02135	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS02140	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL14_RS02145	COG1289	transmembrane transporter activity
CAL14_RS02150	COG1295	ribonuclease BN
CAL14_RS02150	COG1959	2 iron, 2 sulfur cluster binding
CAL14_RS02160	COG0459	protein refolding
CAL14_RS02165	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL14_RS02185	COG2433	Pfam Transposase IS66
CAL14_RS02220	COG0667	Aldo Keto reductase
CAL14_RS02245	COG0583	DNA-binding transcription factor activity
CAL14_RS02250	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS02270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS02275	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL14_RS02290	COG3386	PFAM SMP-30 Gluconolaconase
CAL14_RS02320	COG3744	PilT protein domain protein
CAL14_RS02355	COG4774	siderophore transport
CAL14_RS02360	COG0628	permease
CAL14_RS02375	COG1802	Transcriptional regulator
CAL14_RS02385	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS02405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL14_RS02410	COG0583	DNA-binding transcription factor activity
CAL14_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAL14_RS02435	COG0546	phosphoglycolate phosphatase activity
CAL14_RS02450	COG0583	DNA-binding transcription factor activity
CAL14_RS02460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL14_RS02460	COG1017	nitric oxide dioxygenase activity
CAL14_RS02465	COG0625	glutathione transferase activity
CAL14_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02480	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02485	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02500	COG4172	Belongs to the ABC transporter superfamily
CAL14_RS02510	COG0318	PFAM AMP-dependent synthetase and ligase
CAL14_RS02515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS02520	COG0601	transmembrane transport
CAL14_RS02555	COG0246	Mannitol dehydrogenase
CAL14_RS02560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAL14_RS02575	COG2188	Transcriptional regulator
CAL14_RS02605	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL14_RS02615	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS02620	COG1064	alcohol dehydrogenase
CAL14_RS02625	COG2207	Transcriptional regulator
CAL14_RS02630	COG2207	Transcriptional regulator
CAL14_RS02630	COG4753	response regulator
CAL14_RS02640	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS02665	COG3842	ATPase activity
CAL14_RS02670	COG0583	DNA-binding transcription factor activity
CAL14_RS02675	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS02680	COG0473	3-isopropylmalate dehydrogenase activity
CAL14_RS02680	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS02695	COG1764	response to oxidative stress
CAL14_RS02700	COG0583	DNA-binding transcription factor activity
CAL14_RS02710	COG1595	DNA-templated transcription, initiation
CAL14_RS02785	COG0765	amino acid transport
CAL14_RS02795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS02800	COG0436	Aminotransferase
CAL14_RS02805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS02815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL14_RS02860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS02875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS02880	COG0765	amino acid transport
CAL14_RS02895	COG0402	S-adenosylhomocysteine deaminase activity
CAL14_RS02905	COG3384	dioxygenase
CAL14_RS02910	COG2207	Transcriptional regulator
CAL14_RS02935	COG0583	DNA-binding transcription factor activity
CAL14_RS02940	COG1902	pentaerythritol trinitrate reductase activity
CAL14_RS02960	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS02990	COG2116	formate transmembrane transporter activity
CAL14_RS02995	COG2223	nitrite transmembrane transporter activity
CAL14_RS03020	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS03035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL14_RS03055	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL14_RS03060	COG3971	2-oxopent-4-enoate hydratase activity
CAL14_RS03085	COG1881	PFAM PEBP family protein
CAL14_RS03090	COG0583	DNA-binding transcription factor activity
CAL14_RS03095	COG0626	cystathionine gamma-synthase activity
CAL14_RS03100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS03105	COG0765	amino acid transport
CAL14_RS03110	COG0765	amino acid transport
CAL14_RS03115	COG1126	abc transporter atp-binding protein
CAL14_RS03120	COG3608	succinylglutamate desuccinylase aspartoacylase
CAL14_RS03135	COG0583	DNA-binding transcription factor activity
CAL14_RS03140	COG0477	Major facilitator Superfamily
CAL14_RS03155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS03180	COG5507	3-demethylubiquinone-9 3-methyltransferase
CAL14_RS03190	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS03210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS03220	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS03225	COG0701	Predicted permease
CAL14_RS03255	COG1113	amino acid transport
CAL14_RS03275	COG0583	DNA-binding transcription factor activity
CAL14_RS03290	COG0859	PFAM glycosyl transferase family 9
CAL14_RS03320	COG1902	pentaerythritol trinitrate reductase activity
CAL14_RS03325	COG4297	protein containing double-stranded beta helix domain
CAL14_RS03335	COG5265	(ABC) transporter
CAL14_RS03340	COG1295	ribonuclease BN
CAL14_RS03350	COG0129	dihydroxy-acid dehydratase activity
CAL14_RS03360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL14_RS03395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL14_RS03400	COG0459	protein refolding
CAL14_RS03405	COG3706	GGDEF domain
CAL14_RS03410	COG0840	transmembrane signaling receptor activity
CAL14_RS03420	COG2186	Transcriptional regulator
CAL14_RS03430	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS03455	COG1132	(ABC) transporter
CAL14_RS03460	COG2155	Conserved Protein
CAL14_RS03465	COG2814	Major facilitator Superfamily
CAL14_RS03470	COG2200	EAL domain
CAL14_RS03475	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS03505	COG2733	membrane
CAL14_RS03510	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL14_RS03515	COG0655	NAD(P)H dehydrogenase (quinone) activity
CAL14_RS03530	COG3795	YCII-related domain
CAL14_RS03545	COG4941	Belongs to the sigma-70 factor family
CAL14_RS03565	COG0783	Belongs to the Dps family
CAL14_RS03600	COG0583	DNA-binding transcription factor activity
CAL14_RS03605	COG0038	chloride channel
CAL14_RS03635	COG0463	Glycosyl transferase, family 2
CAL14_RS03645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL14_RS03655	COG0859	PFAM glycosyl transferase family 9
CAL14_RS03665	COG2192	nodulation
CAL14_RS03670	COG0859	PFAM glycosyl transferase family 9
CAL14_RS03675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL14_RS03685	COG0297	glycogen (starch) synthase activity
CAL14_RS03690	COG5265	(ABC) transporter
CAL14_RS03705	COG0741	lytic transglycosylase activity
CAL14_RS03725	COG0477	Major facilitator Superfamily
CAL14_RS03735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS03740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS03745	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CAL14_RS03755	COG2175	clavaminate synthase activity
CAL14_RS03765	COG0583	DNA-binding transcription factor activity
CAL14_RS03770	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS03775	COG0363	glucosamine-6-phosphate deaminase activity
CAL14_RS03780	COG0561	phosphatase activity
CAL14_RS03785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAL14_RS03790	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CAL14_RS03795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAL14_RS03805	COG1940	carbohydrate kinase activity
CAL14_RS03820	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CAL14_RS03850	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL14_RS03855	COG2205	protein histidine kinase activity
CAL14_RS03855	COG4999	Histidine kinase
CAL14_RS03855	COG3850	Histidine kinase
CAL14_RS03855	COG3437	response regulator, receiver
CAL14_RS03855	COG3437	response regulator, receiver
CAL14_RS03855	COG3850	Histidine kinase
CAL14_RS03855	COG4999	Histidine kinase
CAL14_RS03855	COG2205	protein histidine kinase activity
CAL14_RS03860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS03865	COG1285	pathogenesis
CAL14_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS03885	COG2267	carboxylic ester hydrolase activity
CAL14_RS03970	COG1120	ATPase activity
CAL14_RS03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAL14_RS03985	COG2885	chlorophyll binding
CAL14_RS03990	COG0823	Involved in the tonB-independent uptake of proteins
CAL14_RS04000	COG0848	biopolymer transport protein
CAL14_RS04005	COG0811	peptide transport
CAL14_RS04010	COG0824	Thioesterase
CAL14_RS04015	COG0442	prolyl-tRNA aminoacylation
CAL14_RS04030	COG0642	Histidine kinase
CAL14_RS04045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS04050	COG2084	Dehydrogenase
CAL14_RS04090	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAL14_RS04095	COG0129	dihydroxy-acid dehydratase activity
CAL14_RS04150	COG1473	amidohydrolase
CAL14_RS04155	COG0418	dihydroorotase activity
CAL14_RS04160	COG0488	(ABC) transporter
CAL14_RS04170	COG3511	phospholipase C
CAL14_RS04180	COG2001	Belongs to the MraZ family
CAL14_RS04185	COG0275	rRNA processing
CAL14_RS04190	COG3116	cell division
CAL14_RS04205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL14_RS04210	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAL14_RS04225	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAL14_RS04230	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAL14_RS04235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAL14_RS04245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CAL14_RS04250	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CAL14_RS04260	COG0739	heme binding
CAL14_RS04265	COG0653	protein targeting
CAL14_RS04285	COG0028	Belongs to the TPP enzyme family
CAL14_RS04300	COG1522	sequence-specific DNA binding
CAL14_RS04310	COG2239	Acts as a magnesium transporter
CAL14_RS04320	COG2855	membrane
CAL14_RS04330	COG1473	amidohydrolase
CAL14_RS04335	COG0318	PFAM AMP-dependent synthetase and ligase
CAL14_RS04345	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CAL14_RS04345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS04350	COG1501	Belongs to the glycosyl hydrolase 31 family
CAL14_RS04355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAL14_RS04360	COG2011	ABC-type metal ion transport system permease component
CAL14_RS04385	COG2197	response regulator
CAL14_RS04395	COG0745	RESPONSE REGULATOR receiver
CAL14_RS04415	COG4789	Type iii secretion
CAL14_RS04460	COG4669	(LipO)protein
CAL14_RS04495	COG4790	Type iii secretion
CAL14_RS04500	COG4794	Type iii secretion
CAL14_RS04505	COG4791	protein targeting
CAL14_RS04510	COG4792	protein secretion
CAL14_RS04530	COG3300	MHYT domain
CAL14_RS04530	COG5001	Diguanylate cyclase
CAL14_RS04545	COG1368	sulfuric ester hydrolase activity
CAL14_RS04550	COG2982	Protein involved in outer membrane biogenesis
CAL14_RS04570	COG0270	DNA (cytosine-5-)-methyltransferase activity
CAL14_RS04600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL14_RS04610	COG0457	Tetratricopeptide repeat
CAL14_RS04615	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS04640	COG4783	chaperone-mediated protein folding
CAL14_RS04640	COG1560	Kdo2-lipid A biosynthetic process
CAL14_RS04650	COG3866	Pectate lyase
CAL14_RS04655	COG0861	Integral membrane protein TerC family
CAL14_RS04660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAL14_RS04670	COG2186	Transcriptional regulator
CAL14_RS04675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CAL14_RS04700	COG4638	Rieske (2fe-2S)
CAL14_RS04705	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS04710	COG0028	Belongs to the TPP enzyme family
CAL14_RS04720	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS04725	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAL14_RS04730	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS04735	COG0640	Transcriptional regulator
CAL14_RS04745	COG0625	glutathione transferase activity
CAL14_RS04750	COG1126	abc transporter atp-binding protein
CAL14_RS04755	COG0765	amino acid transport
CAL14_RS04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS04770	COG2814	Major facilitator Superfamily
CAL14_RS04775	COG0667	Aldo Keto reductase
CAL14_RS04780	COG0612	Peptidase, M16
CAL14_RS04795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL14_RS04830	COG0745	RESPONSE REGULATOR receiver
CAL14_RS04835	COG2205	protein histidine kinase activity
CAL14_RS04840	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CAL14_RS04845	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CAL14_RS04850	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CAL14_RS04865	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAL14_RS04875	COG1193	negative regulation of DNA recombination
CAL14_RS04880	COG0492	ferredoxin-NADP+ reductase activity
CAL14_RS04885	COG1674	ftsk spoiiie
CAL14_RS04890	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CAL14_RS04900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL14_RS04925	COG0601	transmembrane transport
CAL14_RS04930	COG0747	negative chemotaxis
CAL14_RS04940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAL14_RS04945	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAL14_RS04965	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL14_RS04980	COG2188	Transcriptional regulator
CAL14_RS05005	COG1294	oxidase, subunit
CAL14_RS05010	COG1271	oxidase subunit
CAL14_RS05020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAL14_RS05025	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CAL14_RS05030	COG2828	Protein conserved in bacteria
CAL14_RS05035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS05035	COG2205	protein histidine kinase activity
CAL14_RS05040	COG2197	response regulator
CAL14_RS05050	COG0667	Aldo Keto reductase
CAL14_RS05055	COG2207	Transcriptional regulator
CAL14_RS05060	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CAL14_RS05075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAL14_RS05080	COG1845	cytochrome c oxidase, subunit III
CAL14_RS05085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL14_RS05090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL14_RS05095	COG0477	Major facilitator Superfamily
CAL14_RS05100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL14_RS05105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL14_RS05115	COG1252	NADH dehydrogenase
CAL14_RS05145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAL14_RS05145	COG0475	glutathione-regulated potassium exporter activity
CAL14_RS05150	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS05155	COG3022	response to hydroperoxide
CAL14_RS05160	COG1289	transmembrane transporter activity
CAL14_RS05165	COG0028	Belongs to the TPP enzyme family
CAL14_RS05170	COG0440	acetolactate synthase activity
CAL14_RS05175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAL14_RS05180	COG0688	phosphatidylethanolamine metabolic process
CAL14_RS05185	COG1183	phosphatidylcholine synthase activity
CAL14_RS05195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAL14_RS05200	COG1185	polyribonucleotide nucleotidyltransferase activity
CAL14_RS05210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL14_RS05225	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CAL14_RS05240	COG1802	Transcriptional regulator
CAL14_RS05250	COG1024	Enoyl-CoA hydratase
CAL14_RS05255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS05260	COG1802	Transcriptional regulator
CAL14_RS05265	COG0277	FAD linked oxidase domain protein
CAL14_RS05265	COG0247	lactate metabolic process
CAL14_RS05285	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAL14_RS05300	COG1846	Transcriptional regulator
CAL14_RS05300	COG0456	acetyltransferase
CAL14_RS05305	COG0300	oxidoreductase activity
CAL14_RS05310	COG0028	Belongs to the TPP enzyme family
CAL14_RS05320	COG0149	triose-phosphate isomerase activity
CAL14_RS05325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL14_RS05495	COG0305	Participates in initiation and elongation during chromosome replication
CAL14_RS05535	COG4626	Terminase
CAL14_RS05535	COG1802	Transcriptional regulator
CAL14_RS05660	COG2814	Major facilitator Superfamily
CAL14_RS05665	COG3265	gluconokinase activity
CAL14_RS05700	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS05710	COG0668	transmembrane transport
CAL14_RS05720	COG2133	pyrroloquinoline quinone binding
CAL14_RS05730	COG0583	DNA-binding transcription factor activity
CAL14_RS05740	COG0405	Gamma-glutamyltransferase
CAL14_RS05745	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL14_RS05750	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL14_RS05755	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL14_RS05760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL14_RS05765	COG0649	NAD binding
CAL14_RS05770	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CAL14_RS05780	COG1034	ATP synthesis coupled electron transport
CAL14_RS05780	COG1034	ATP synthesis coupled electron transport
CAL14_RS05785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CAL14_RS05790	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL14_RS05800	COG0713	ATP synthesis coupled electron transport
CAL14_RS05815	COG1007	ATP synthesis coupled electron transport
CAL14_RS05830	COG4774	siderophore transport
CAL14_RS05835	COG0560	Phosphoserine phosphatase
CAL14_RS05840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAL14_RS05845	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAL14_RS05850	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CAL14_RS05855	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL14_RS05860	COG0450	alkyl hydroperoxide reductase
CAL14_RS05875	COG1214	PFAM Peptidase M22, glycoprotease
CAL14_RS05880	COG1573	uracil-dna glycosylase
CAL14_RS05885	COG0477	Major facilitator Superfamily
CAL14_RS05890	COG1196	nuclear chromosome segregation
CAL14_RS05900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAL14_RS05905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL14_RS05915	COG2917	probably involved in intracellular septation
CAL14_RS05920	COG1122	ATPase activity
CAL14_RS05925	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CAL14_RS05930	COG1268	BioY protein
CAL14_RS05965	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS05975	COG0583	DNA-binding transcription factor activity
CAL14_RS05995	COG3264	Mechanosensitive ion channel
CAL14_RS05995	COG1196	nuclear chromosome segregation
CAL14_RS06005	COG0583	DNA-binding transcription factor activity
CAL14_RS06055	COG0477	Major facilitator Superfamily
CAL14_RS06065	COG1414	Transcriptional regulator
CAL14_RS06070	COG2084	Dehydrogenase
CAL14_RS06075	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS06100	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS06105	COG4177	L-phenylalanine transmembrane transporter activity
CAL14_RS06125	COG0625	glutathione transferase activity
CAL14_RS06130	COG0625	glutathione transferase activity
CAL14_RS06140	COG2079	MmgE PrpD family protein
CAL14_RS06155	COG0039	L-malate dehydrogenase activity
CAL14_RS06160	COG2188	Transcriptional regulator
CAL14_RS06165	COG2009	succinate dehydrogenase
CAL14_RS06170	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CAL14_RS06175	COG1053	succinate dehydrogenase
CAL14_RS06180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAL14_RS06185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CAL14_RS06190	COG0372	Belongs to the citrate synthase family
CAL14_RS06200	COG0281	malic enzyme
CAL14_RS06200	COG0280	phosphate acetyltransferase
CAL14_RS06205	COG0567	Dehydrogenase, E1 component
CAL14_RS06210	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL14_RS06215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL14_RS06220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CAL14_RS06250	COG2183	response to ionizing radiation
CAL14_RS06255	COG1199	ATP-dependent helicase activity
CAL14_RS06265	COG0564	pseudouridine synthase activity
CAL14_RS06275	COG3243	poly(R)-hydroxyalkanoic acid synthase
CAL14_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS06285	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CAL14_RS06300	COG0672	)-iron permease
CAL14_RS06315	COG2823	Periplasmic or secreted lipoprotein
CAL14_RS06325	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL14_RS06325	COG0189	ligase activity
CAL14_RS06330	COG0189	ligase activity
CAL14_RS06330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL14_RS06335	COG1132	(ABC) transporter
CAL14_RS06345	COG0246	Mannitol dehydrogenase
CAL14_RS06350	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS06360	COG1802	Transcriptional regulator
CAL14_RS06370	COG2833	Protein of unknown function (DUF455)
CAL14_RS06380	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL14_RS06385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS06395	COG2721	sulfolactate sulfo-lyase activity
CAL14_RS06400	COG2721	sulfolactate sulfo-lyase activity
CAL14_RS06405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL14_RS06415	COG0494	nUDIX hydrolase
CAL14_RS06425	COG1733	regulation of RNA biosynthetic process
CAL14_RS06445	COG2814	Major facilitator Superfamily
CAL14_RS06465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAL14_RS06485	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAL14_RS06490	COG1605	Chorismate mutase
CAL14_RS06490	COG0077	Prephenate dehydratase
CAL14_RS06495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL14_RS06500	COG0287	Prephenate dehydrogenase
CAL14_RS06505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAL14_RS06510	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAL14_RS06530	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CAL14_RS06535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CAL14_RS06540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL14_RS06545	COG1596	polysaccharide export
CAL14_RS06545	COG1555	photosystem II stabilization
CAL14_RS06560	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAL14_RS06575	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS06580	COG0450	alkyl hydroperoxide reductase
CAL14_RS06585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CAL14_RS06590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL14_RS06595	COG4208	sulfate ABC transporter
CAL14_RS06600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL14_RS06605	COG0175	sulfate reduction
CAL14_RS06630	COG0335	large ribosomal subunit rRNA binding
CAL14_RS06640	COG1162	GTPase activity
CAL14_RS06645	COG0501	Belongs to the peptidase M48B family
CAL14_RS06650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CAL14_RS06655	COG3327	negative regulation of DNA-templated transcription, initiation
CAL14_RS06660	COG3396	Phenylacetate-CoA oxygenase
CAL14_RS06665	COG3460	Phenylacetate-CoA oxygenase
CAL14_RS06670	COG3396	Phenylacetate-CoA oxygenase
CAL14_RS06675	COG2151	metal-sulfur cluster biosynthetic enzyme
CAL14_RS06680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL14_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS06690	COG1024	Enoyl-CoA hydratase
CAL14_RS06695	COG2050	protein possibly involved in aromatic compounds catabolism
CAL14_RS06705	COG0534	Mate efflux family protein
CAL14_RS06720	COG2003	Belongs to the UPF0758 family
CAL14_RS06730	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAL14_RS06735	COG0625	glutathione transferase activity
CAL14_RS06740	COG2721	sulfolactate sulfo-lyase activity
CAL14_RS06755	COG2188	Transcriptional regulator
CAL14_RS06765	COG0640	Transcriptional regulator
CAL14_RS06800	COG1546	Belongs to the CinA family
CAL14_RS06800	COG1058	Belongs to the CinA family
CAL14_RS06810	COG0514	ATP-dependent DNA helicase (RecQ)
CAL14_RS06870	COG2814	Major facilitator Superfamily
CAL14_RS06880	COG3622	Belongs to the hyi family
CAL14_RS06885	COG0251	oxidation-reduction process
CAL14_RS06890	COG0523	cobalamin synthesis protein
CAL14_RS06900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAL14_RS06905	COG1187	pseudouridine synthase activity
CAL14_RS06910	COG0779	Required for maturation of 30S ribosomal subunits
CAL14_RS06915	COG2251	uridine kinase activity
CAL14_RS06915	COG0195	Participates in both transcription termination and antitermination
CAL14_RS06920	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAL14_RS06925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAL14_RS06930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAL14_RS06935	COG1217	gtp-binding protein TYPA
CAL14_RS06950	COG0830	nickel cation binding
CAL14_RS06955	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CAL14_RS06965	COG0832	Belongs to the urease beta subunit family
CAL14_RS06975	COG0831	urea catabolic process
CAL14_RS06990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAL14_RS06990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAL14_RS06995	COG4221	oxidoreductase activity
CAL14_RS07005	COG1283	sodium-dependent phosphate transmembrane transporter activity
CAL14_RS07010	COG1760	l-serine dehydratase
CAL14_RS07015	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS07020	COG0501	Belongs to the peptidase M48B family
CAL14_RS07045	COG1722	exodeoxyribonuclease VII activity
CAL14_RS07050	COG0142	geranyltranstransferase activity
CAL14_RS07060	COG1469	GTP cyclohydrolase I activity
CAL14_RS07065	COG0360	Binds together with S18 to 16S ribosomal RNA
CAL14_RS07070	COG2965	DNA replication, synthesis of RNA primer
CAL14_RS07075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CAL14_RS07080	COG0359	binds to the 23S rRNA
CAL14_RS07090	COG0305	Participates in initiation and elongation during chromosome replication
CAL14_RS07100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CAL14_RS07105	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAL14_RS07110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAL14_RS07115	COG3737	Protein of unknown function (DUF498/DUF598)
CAL14_RS07120	COG0436	Aminotransferase
CAL14_RS07135	COG1131	(ABC) transporter
CAL14_RS07140	COG0842	Transport permease protein
CAL14_RS07145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAL14_RS07160	COG1562	ergosterol biosynthetic process
CAL14_RS07165	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAL14_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS07185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAL14_RS07205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CAL14_RS07220	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CAL14_RS07225	COG3842	ATPase activity
CAL14_RS07230	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL14_RS07235	COG1177	transmembrane transport
CAL14_RS07240	COG1393	Belongs to the ArsC family
CAL14_RS07260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CAL14_RS07265	COG0704	Plays a role in the regulation of phosphate uptake
CAL14_RS07270	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CAL14_RS07275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL14_RS07275	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAL14_RS07285	COG1643	Atp-dependent helicase
CAL14_RS07300	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS07305	COG0726	polysaccharide deacetylase
CAL14_RS07310	COG0463	Glycosyl transferase, family 2
CAL14_RS07315	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS07355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL14_RS07405	COG1132	(ABC) transporter
CAL14_RS07445	COG1301	dicarboxylic acid transport
CAL14_RS07455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS07460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS07490	COG0596	Alpha beta hydrolase
CAL14_RS07495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL14_RS07500	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS07505	COG1802	Transcriptional regulator
CAL14_RS07510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAL14_RS07520	COG0156	8-amino-7-oxononanoate synthase activity
CAL14_RS07535	COG0424	maF-like protein
CAL14_RS07540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CAL14_RS07545	COG0799	negative regulation of ribosome biogenesis
CAL14_RS07550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAL14_RS07560	COG0151	Belongs to the GarS family
CAL14_RS07565	COG0217	transcriptional regulatory protein
CAL14_RS07570	COG0433	COG0433 Predicted ATPase
CAL14_RS07575	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL14_RS07580	COG0473	3-isopropylmalate dehydrogenase activity
CAL14_RS07590	COG2814	Major facilitator Superfamily
CAL14_RS07595	COG1566	PFAM secretion protein HlyD family protein
CAL14_RS07605	COG1846	Transcriptional regulator
CAL14_RS07625	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAL14_RS07630	COG0308	aminopeptidase N
CAL14_RS07650	COG0312	modulator of DNA gyrase
CAL14_RS07655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL14_RS07660	COG0277	FAD linked oxidase domain protein
CAL14_RS07665	COG0277	FAD linked oxidase domain protein
CAL14_RS07670	COG0277	FAD linked oxidase domain protein
CAL14_RS07675	COG0247	lactate metabolic process
CAL14_RS07695	COG0482	sulfurtransferase activity
CAL14_RS07700	COG0730	response to heat
CAL14_RS07705	COG0625	glutathione transferase activity
CAL14_RS07730	COG1278	Cold shock
CAL14_RS07750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAL14_RS07755	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CAL14_RS07775	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL14_RS07790	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL14_RS07800	COG2204	response regulator
CAL14_RS07805	COG2204	response regulator
CAL14_RS07810	COG0693	protein deglycase activity
CAL14_RS07825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CAL14_RS07845	COG3048	D-serine ammonia-lyase activity
CAL14_RS07855	COG0557	exoribonuclease II activity
CAL14_RS07860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL14_RS07865	COG2873	o-acetylhomoserine
CAL14_RS07870	COG3128	pkhd-type hydroxylase
CAL14_RS07875	COG0776	regulation of translation
CAL14_RS07890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL14_RS07900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS07905	COG2301	Belongs to the HpcH HpaI aldolase family
CAL14_RS07910	COG0583	DNA-binding transcription factor activity
CAL14_RS07935	COG0642	Histidine kinase
CAL14_RS07940	COG3158	transport of potassium into the cell
CAL14_RS07950	COG2814	Major facilitator Superfamily
CAL14_RS07955	COG0154	amidase activity
CAL14_RS07960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAL14_RS07970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL14_RS07985	COG2186	Transcriptional regulator
CAL14_RS07995	COG3836	Belongs to the HpcH HpaI aldolase family
CAL14_RS08000	COG0268	Binds directly to 16S ribosomal RNA
CAL14_RS08010	COG0728	peptidoglycan biosynthetic process
CAL14_RS08020	COG0563	adenylate kinase activity
CAL14_RS08025	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CAL14_RS08030	COG2835	tetraacyldisaccharide 4'-kinase activity
CAL14_RS08040	COG0848	biopolymer transport protein
CAL14_RS08045	COG0811	peptide transport
CAL14_RS08050	COG1570	exodeoxyribonuclease VII activity
CAL14_RS08055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL14_RS08065	COG0183	Belongs to the thiolase family
CAL14_RS08075	COG1278	Cold shock
CAL14_RS08080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CAL14_RS08085	COG0542	response to heat
CAL14_RS08090	COG2995	paraquat-inducible protein a
CAL14_RS08095	COG3008	intermembrane lipid transfer
CAL14_RS08095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL14_RS08105	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL14_RS08105	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL14_RS08105	COG0506	proline dehydrogenase activity
CAL14_RS08125	COG0411	ABC transporter
CAL14_RS08135	COG1914	H( )-stimulated, divalent metal cation uptake system
CAL14_RS08140	COG1764	response to oxidative stress
CAL14_RS08155	COG1902	pentaerythritol trinitrate reductase activity
CAL14_RS08160	COG0756	dUTP diphosphatase activity
CAL14_RS08175	COG1988	membrane-bound metal-dependent
CAL14_RS08180	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAL14_RS08185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAL14_RS08190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAL14_RS08195	COG0196	riboflavin kinase activity
CAL14_RS08200	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAL14_RS08205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL14_RS08205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL14_RS08220	COG0210	DNA helicase
CAL14_RS08225	COG0488	(ABC) transporter
CAL14_RS08230	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL14_RS08240	COG2171	N-acyltransferase activity
CAL14_RS08245	COG0436	Aminotransferase
CAL14_RS08255	COG0582	viral genome integration into host DNA
CAL14_RS08465	COG3566	protein conserved in bacteria
CAL14_RS08630	COG1278	Cold shock
CAL14_RS08645	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAL14_RS08650	COG0740	serine-type endopeptidase activity
CAL14_RS08655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CAL14_RS08660	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAL14_RS08665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CAL14_RS08675	COG0556	nucleotide-excision repair
CAL14_RS08680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAL14_RS08690	COG1104	cysteine desulfurase activity
CAL14_RS08695	COG0822	iron-sulfur transferase activity
CAL14_RS08700	COG0316	Belongs to the HesB IscA family
CAL14_RS08710	COG0443	Heat shock 70 kDa protein
CAL14_RS08715	COG0633	Ferredoxin
CAL14_RS08725	COG1803	Methylglyoxal synthase
CAL14_RS08730	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAL14_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS08745	COG2271	Major facilitator Superfamily
CAL14_RS08770	COG1136	(ABC) transporter
CAL14_RS08775	COG0084	hydrolase, TatD family'
CAL14_RS08795	COG0613	PHP domain protein
CAL14_RS08805	COG0047	phosphoribosylformylglycinamidine synthase activity
CAL14_RS08805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAL14_RS08825	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL14_RS08835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL14_RS08835	COG0519	Catalyzes the synthesis of GMP from XMP
CAL14_RS08840	COG4691	Plasmid stability protein
CAL14_RS08845	COG1487	ribonuclease activity
CAL14_RS08885	COG0583	DNA-binding transcription factor activity
CAL14_RS08900	COG0789	Transcriptional regulator
CAL14_RS08905	COG0477	Major facilitator Superfamily
CAL14_RS08930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL14_RS08940	COG2814	Major facilitator Superfamily
CAL14_RS08945	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAL14_RS08990	COG0659	secondary active sulfate transmembrane transporter activity
CAL14_RS08995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL14_RS09000	COG1522	sequence-specific DNA binding
CAL14_RS09005	COG0583	DNA-binding transcription factor activity
CAL14_RS09015	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL14_RS09020	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL14_RS09025	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL14_RS09030	COG0583	DNA-binding transcription factor activity
CAL14_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS09040	COG0477	Major facilitator Superfamily
CAL14_RS09055	COG0477	Major facilitator Superfamily
CAL14_RS09070	COG3842	ATPase activity
CAL14_RS09080	COG0395	ABC-type sugar transport system, permease component
CAL14_RS09095	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS09100	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS09105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAL14_RS09110	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL14_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS09150	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL14_RS09150	COG0824	Thioesterase
CAL14_RS09155	COG3246	L-lysine catabolic process to acetate
CAL14_RS09160	COG0371	Dehydrogenase
CAL14_RS09165	COG1802	Transcriptional regulator
CAL14_RS09170	COG3959	Transketolase, thiamine diphosphate binding domain
CAL14_RS09175	COG3958	Transketolase
CAL14_RS09180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL14_RS09195	COG1136	(ABC) transporter
CAL14_RS09200	COG0577	efflux transmembrane transporter activity
CAL14_RS09220	COG1566	PFAM secretion protein HlyD family protein
CAL14_RS09230	COG1289	transmembrane transporter activity
CAL14_RS09250	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL14_RS09260	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL14_RS09270	COG0366	Alpha amylase catalytic
CAL14_RS09275	COG0297	glycogen (starch) synthase activity
CAL14_RS09280	COG1793	dna ligase
CAL14_RS09280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAL14_RS09285	COG1793	dna ligase
CAL14_RS09310	COG0726	polysaccharide deacetylase
CAL14_RS09315	COG2814	Major facilitator Superfamily
CAL14_RS09320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL14_RS09325	COG0720	synthase
CAL14_RS09330	COG0602	queuosine metabolic process
CAL14_RS09335	COG2252	PERMEase
CAL14_RS09340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAL14_RS09345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CAL14_RS09350	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CAL14_RS09355	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL14_RS09380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAL14_RS09385	COG0165	Argininosuccinate lyase
CAL14_RS09400	COG2154	pterin-4-alpha-carbinolamine dehydratase
CAL14_RS09415	COG0747	negative chemotaxis
CAL14_RS09420	COG0601	transmembrane transport
CAL14_RS09425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS09430	COG4172	Belongs to the ABC transporter superfamily
CAL14_RS09440	COG4681	YaeQ
CAL14_RS09445	COG3161	chorismate lyase activity
CAL14_RS09450	COG1187	pseudouridine synthase activity
CAL14_RS09465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL14_RS09480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CAL14_RS09485	COG0584	glycerophosphoryl diester phosphodiesterase
CAL14_RS09490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL14_RS09500	COG4181	ATPase activity
CAL14_RS09525	COG4336	lyase activity
CAL14_RS09555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAL14_RS09580	COG1522	sequence-specific DNA binding
CAL14_RS09590	COG0386	Belongs to the glutathione peroxidase family
CAL14_RS09600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS09605	COG1393	Belongs to the ArsC family
CAL14_RS09620	COG2259	Doxx family
CAL14_RS09625	COG0010	Belongs to the arginase family
CAL14_RS09640	COG3842	ATPase activity
CAL14_RS09645	COG0395	ABC-type sugar transport system, permease component
CAL14_RS09650	COG1175	transmembrane transport
CAL14_RS09655	COG1653	transport
CAL14_RS09670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAL14_RS09675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CAL14_RS09685	COG0084	hydrolase, TatD family'
CAL14_RS09695	COG1742	UPF0060 membrane protein
CAL14_RS09710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS09715	COG0765	amino acid transport
CAL14_RS09720	COG1126	abc transporter atp-binding protein
CAL14_RS09725	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL14_RS09730	COG1758	RNA polymerase activity
CAL14_RS09735	COG0194	GDP metabolic process
CAL14_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS09745	COG0791	NLP P60 protein
CAL14_RS09750	COG4206	TonB-dependent receptor
CAL14_RS09760	COG3781	membrane
CAL14_RS09765	COG2304	oxidoreductase activity
CAL14_RS09770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL14_RS09775	COG0714	Associated with various cellular activities
CAL14_RS09785	COG2304	oxidoreductase activity
CAL14_RS09790	COG1561	YicC-like family, N-terminal region
CAL14_RS09795	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CAL14_RS09800	COG0840	transmembrane signaling receptor activity
CAL14_RS09805	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CAL14_RS09810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAL14_RS09815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAL14_RS09820	COG0174	glutamine synthetase
CAL14_RS09835	COG0583	DNA-binding transcription factor activity
CAL14_RS09840	COG1741	Belongs to the pirin family
CAL14_RS09845	COG1741	Belongs to the pirin family
CAL14_RS09850	COG3842	ATPase activity
CAL14_RS09855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL14_RS09860	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL14_RS09870	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS09895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAL14_RS09900	COG0583	DNA-binding transcription factor activity
CAL14_RS09910	COG0783	Belongs to the Dps family
CAL14_RS09925	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAL14_RS09940	COG1454	alcohol dehydrogenase
CAL14_RS09950	COG2070	2-Nitropropane dioxygenase
CAL14_RS09965	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS09970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS09975	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL14_RS09980	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS09990	COG1802	Transcriptional regulator
CAL14_RS09995	COG4948	Mandelate Racemase Muconate Lactonizing
CAL14_RS10020	COG2188	Transcriptional regulator
CAL14_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS10050	COG2197	response regulator
CAL14_RS10055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAL14_RS10090	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS10100	COG1902	pentaerythritol trinitrate reductase activity
CAL14_RS10115	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL14_RS10140	COG0747	negative chemotaxis
CAL14_RS10145	COG4608	Belongs to the ABC transporter superfamily
CAL14_RS10160	COG0601	transmembrane transport
CAL14_RS10165	COG2072	flavoprotein involved in K transport
CAL14_RS10180	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CAL14_RS10190	COG0656	L-ascorbic acid biosynthetic process
CAL14_RS10205	COG1477	protein flavinylation
CAL14_RS10230	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS10265	COG0583	DNA-binding transcription factor activity
CAL14_RS10275	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS10290	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CAL14_RS10295	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CAL14_RS10305	COG0596	Alpha beta hydrolase
CAL14_RS10330	COG0431	NADPH-dependent FMN reductase
CAL14_RS10345	COG0640	Transcriptional regulator
CAL14_RS10380	COG2301	Belongs to the HpcH HpaI aldolase family
CAL14_RS10390	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CAL14_RS10395	COG1024	Enoyl-CoA hydratase
CAL14_RS10400	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS10405	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS10415	COG0183	Belongs to the thiolase family
CAL14_RS10430	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS10445	COG2030	dehydratase
CAL14_RS10455	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS10475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL14_RS10490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CAL14_RS10495	COG1671	Belongs to the UPF0178 family
CAL14_RS10510	COG0583	DNA-binding transcription factor activity
CAL14_RS10515	COG1380	Effector of murein hydrolase LrgA
CAL14_RS10520	COG1346	cytolysis
CAL14_RS10530	COG2201	protein-glutamate methylesterase activity
CAL14_RS10580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS10600	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS10615	COG0583	DNA-binding transcription factor activity
CAL14_RS10635	COG3008	intermembrane lipid transfer
CAL14_RS10660	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS10670	COG0583	DNA-binding transcription factor activity
CAL14_RS10695	COG4191	Histidine kinase
CAL14_RS10695	COG0784	Response regulator, receiver
CAL14_RS10700	COG1506	peptidase
CAL14_RS10700	COG0823	Involved in the tonB-independent uptake of proteins
CAL14_RS10700	COG4946	Tricorn protease homolog
CAL14_RS10715	COG2202	Pas domain
CAL14_RS10715	COG3920	Histidine kinase
CAL14_RS10780	COG1090	epimerase
CAL14_RS10805	COG1132	(ABC) transporter
CAL14_RS10825	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS10840	COG2159	amidohydrolase
CAL14_RS10845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL14_RS10865	COG0583	DNA-binding transcription factor activity
CAL14_RS10880	COG4251	negative regulation of phosphorylation
CAL14_RS10885	COG0784	Response regulator, receiver
CAL14_RS10940	COG1942	4-Oxalocrotonate Tautomerase
CAL14_RS10965	COG1309	transcriptional regulator
CAL14_RS10995	COG0165	Argininosuccinate lyase
CAL14_RS11000	COG0697	spore germination
CAL14_RS11010	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS11025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS11055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL14_RS11075	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CAL14_RS11080	COG1335	isochorismatase
CAL14_RS11085	COG2309	aminopeptidase activity
CAL14_RS11090	COG0596	Alpha beta hydrolase
CAL14_RS11095	COG3473	Maleate cis-trans isomerase
CAL14_RS11120	COG2423	ornithine cyclodeaminase activity
CAL14_RS11135	COG2267	carboxylic ester hydrolase activity
CAL14_RS11140	COG1228	amidohydrolase
CAL14_RS11145	COG1879	ABC-type sugar transport system periplasmic component
CAL14_RS11155	COG1172	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS11165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL14_RS11165	COG2010	Cytochrome c
CAL14_RS11180	COG2010	Cytochrome c
CAL14_RS11195	COG3976	FMN-binding domain protein
CAL14_RS11195	COG1053	succinate dehydrogenase
CAL14_RS11205	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS11225	COG1609	Transcriptional regulator
CAL14_RS11245	COG0432	Pfam Uncharacterised protein family UPF0047
CAL14_RS11265	COG0405	Gamma-glutamyltransferase
CAL14_RS11270	COG0583	DNA-binding transcription factor activity
CAL14_RS11290	COG1216	Glycosyl transferase, family 2
CAL14_RS11315	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAL14_RS11315	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CAL14_RS11325	COG3550	peptidyl-serine autophosphorylation
CAL14_RS11355	COG0642	Histidine kinase
CAL14_RS11360	COG1304	FMN binding
CAL14_RS11375	COG1538	Outer membrane efflux protein
CAL14_RS11380	COG0473	3-isopropylmalate dehydrogenase activity
CAL14_RS11385	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS11405	COG0596	Alpha beta hydrolase
CAL14_RS11410	COG1228	amidohydrolase
CAL14_RS11435	COG5441	Belongs to the UPF0261 family
CAL14_RS11440	COG5564	TIM-barrel signal transduction protein
CAL14_RS11445	COG2268	Band 7 protein
CAL14_RS11455	COG0583	DNA-binding transcription factor activity
CAL14_RS11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS11480	COG2205	protein histidine kinase activity
CAL14_RS11505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL14_RS11515	COG0583	DNA-binding transcription factor activity
CAL14_RS11520	COG0735	belongs to the Fur family
CAL14_RS11525	COG0628	permease
CAL14_RS11530	COG1464	Belongs to the NlpA lipoprotein family
CAL14_RS11535	COG0288	reversible hydration of carbon dioxide
CAL14_RS11545	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS11550	COG4974	Belongs to the 'phage' integrase family
CAL14_RS11565	COG1116	anion transmembrane transporter activity
CAL14_RS11570	COG0395	ABC-type sugar transport system, permease component
CAL14_RS11580	COG2363	Small membrane protein
CAL14_RS11590	COG2814	Major facilitator Superfamily
CAL14_RS11605	COG0390	transport system, permease component
CAL14_RS11625	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL14_RS11645	COG0411	ABC transporter
CAL14_RS11655	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS11675	COG1024	Enoyl-CoA hydratase
CAL14_RS11680	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS11685	COG2914	Belongs to the UPF0125 (RnfH) family
CAL14_RS11695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CAL14_RS11705	COG0330	HflC and HflK could
CAL14_RS11715	COG0519	Catalyzes the synthesis of GMP from XMP
CAL14_RS11715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL14_RS11720	COG2169	Transcriptional regulator
CAL14_RS11720	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL14_RS11735	COG0640	Transcriptional regulator
CAL14_RS11740	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAL14_RS11745	COG2814	Major facilitator Superfamily
CAL14_RS11750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL14_RS11755	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAL14_RS11760	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL14_RS11770	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAL14_RS11775	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL14_RS11780	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CAL14_RS11790	COG0750	zinc metalloprotease
CAL14_RS11795	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAL14_RS11800	COG0575	Belongs to the CDS family
CAL14_RS11805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAL14_RS11810	COG0233	cytoplasmic translational termination
CAL14_RS11815	COG0528	UMP kinase activity
CAL14_RS11820	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAL14_RS11825	COG0052	Belongs to the universal ribosomal protein uS2 family
CAL14_RS11830	COG0024	Methionine aminopeptidase
CAL14_RS11835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CAL14_RS11865	COG0285	dihydrofolate synthase activity
CAL14_RS11870	COG1334	flagellar protein FlaG
CAL14_RS11875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAL14_RS11895	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAL14_RS11905	COG5001	Diguanylate cyclase
CAL14_RS11905	COG3300	MHYT domain
CAL14_RS11910	COG1677	Flagellar hook-basal body complex protein FliE
CAL14_RS11920	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL14_RS11945	COG1580	Controls the rotational direction of flagella during chemotaxis
CAL14_RS11950	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL14_RS11955	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL14_RS12000	COG0840	transmembrane signaling receptor activity
CAL14_RS12005	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAL14_RS12015	COG1256	bacterial-type flagellum assembly
CAL14_RS12020	COG1705	Flagellar rod assembly protein muramidase FlgJ
CAL14_RS12020	COG3951	Flagellar rod assembly protein muramidase FlgJ
CAL14_RS12040	COG4787	bacterial-type flagellum-dependent cell motility
CAL14_RS12055	COG1558	bacterial-type flagellum-dependent cell motility
CAL14_RS12065	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CAL14_RS12090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAL14_RS12095	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CAL14_RS12100	COG0745	RESPONSE REGULATOR receiver
CAL14_RS12105	COG2201	protein-glutamate methylesterase activity
CAL14_RS12110	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL14_RS12115	COG0840	transmembrane signaling receptor activity
CAL14_RS12120	COG0835	chemotaxis
CAL14_RS12130	COG0745	RESPONSE REGULATOR receiver
CAL14_RS12155	COG1191	sigma factor activity
CAL14_RS12165	COG4797	methyltransferase
CAL14_RS12165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL14_RS12170	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL14_RS12175	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL14_RS12190	COG4566	intracellular signal transduction
CAL14_RS12195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAL14_RS12200	COG0339	signal peptide processing
CAL14_RS12205	COG1999	signal sequence binding
CAL14_RS12220	COG0678	peroxiredoxin activity
CAL14_RS12220	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAL14_RS12235	COG0789	Transcriptional regulator
CAL14_RS12245	COG0789	Transcriptional regulator
CAL14_RS12285	COG2197	response regulator
CAL14_RS12295	COG2274	protein secretion by the type I secretion system
CAL14_RS12305	COG1538	Outer membrane efflux protein
CAL14_RS12340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CAL14_RS12350	COG3642	lipopolysaccharide core region biosynthetic process
CAL14_RS12365	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CAL14_RS12375	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAL14_RS12380	COG0667	Aldo Keto reductase
CAL14_RS12385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL14_RS12405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAL14_RS12410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL14_RS12420	COG0488	(ABC) transporter
CAL14_RS12435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAL14_RS12435	COG4651	solute:proton antiporter activity
CAL14_RS12440	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAL14_RS12445	COG0590	tRNA wobble adenosine to inosine editing
CAL14_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS12485	COG2951	lytic endotransglycosylase activity
CAL14_RS12510	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS12525	COG0583	DNA-binding transcription factor activity
CAL14_RS12530	COG0477	Major facilitator Superfamily
CAL14_RS12540	COG0656	L-ascorbic acid biosynthetic process
CAL14_RS12560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS12565	COG1126	abc transporter atp-binding protein
CAL14_RS12570	COG0765	amino acid transport
CAL14_RS12575	COG0765	amino acid transport
CAL14_RS12595	COG0583	DNA-binding transcription factor activity
CAL14_RS12600	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS12605	COG1201	RNA secondary structure unwinding
CAL14_RS12630	COG3237	CsbD-like
CAL14_RS12635	COG4774	siderophore transport
CAL14_RS12640	COG2375	cellular response to nickel ion
CAL14_RS12645	COG1695	Transcriptional regulator
CAL14_RS12660	COG0587	DNA-directed DNA polymerase activity
CAL14_RS12675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS12680	COG0583	DNA-binding transcription factor activity
CAL14_RS12695	COG0204	Acyl-transferase
CAL14_RS12700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL14_RS12705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL14_RS12765	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS12770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAL14_RS12805	COG2223	nitrite transmembrane transporter activity
CAL14_RS12810	COG2207	Transcriptional regulator
CAL14_RS12820	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL14_RS12830	COG5265	(ABC) transporter
CAL14_RS12880	COG0745	RESPONSE REGULATOR receiver
CAL14_RS12885	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL14_RS12905	COG0072	phenylalanine-tRNA ligase activity
CAL14_RS12905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAL14_RS12910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CAL14_RS12915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CAL14_RS12920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CAL14_RS12940	COG0004	ammonium transporteR
CAL14_RS12945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAL14_RS12950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAL14_RS12965	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CAL14_RS12970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAL14_RS12975	COG2197	response regulator
CAL14_RS12980	COG5002	protein histidine kinase activity
CAL14_RS12980	COG2205	protein histidine kinase activity
CAL14_RS12980	COG0784	Response regulator, receiver
CAL14_RS12990	COG2200	EAL domain
CAL14_RS13000	COG0135	phosphoribosylanthranilate isomerase activity
CAL14_RS13005	COG0101	tRNA pseudouridine synthase activity
CAL14_RS13015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAL14_RS13040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAL14_RS13055	COG2205	protein histidine kinase activity
CAL14_RS13060	COG0745	RESPONSE REGULATOR receiver
CAL14_RS13065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CAL14_RS13075	COG1295	ribonuclease BN
CAL14_RS13080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CAL14_RS13080	COG0517	IMP dehydrogenase activity
CAL14_RS13085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAL14_RS13175	COG0181	hydroxymethylbilane synthase activity
CAL14_RS13180	COG0861	Integral membrane protein TerC family
CAL14_RS13185	COG0861	Integral membrane protein TerC family
CAL14_RS13190	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS13200	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CAL14_RS13205	COG0045	succinate-CoA ligase (ADP-forming) activity
CAL14_RS13215	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAL14_RS13225	COG2137	regulation of response to DNA damage stimulus
CAL14_RS13230	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAL14_RS13245	COG0477	Major facilitator Superfamily
CAL14_RS13270	COG0540	Belongs to the ATCase OTCase family
CAL14_RS13320	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CAL14_RS13330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS13370	COG0477	Major facilitator Superfamily
CAL14_RS13375	COG1686	Belongs to the peptidase S11 family
CAL14_RS13385	COG1297	OPT oligopeptide transporter protein
CAL14_RS13400	COG0668	transmembrane transport
CAL14_RS13420	COG1278	Cold shock
CAL14_RS13450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAL14_RS13460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CAL14_RS13470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAL14_RS13475	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CAL14_RS13480	COG0330	HflC and HflK could
CAL14_RS13485	COG0330	HflC and HflK could
CAL14_RS13490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAL14_RS13495	COG1923	regulation of RNA biosynthetic process
CAL14_RS13505	COG1160	GTP binding
CAL14_RS13510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL14_RS13535	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAL14_RS13540	COG0105	UTP biosynthetic process
CAL14_RS13545	COG0525	valine-tRNA ligase activity
CAL14_RS13550	COG0336	Belongs to the RNA methyltransferase TrmD family
CAL14_RS13555	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CAL14_RS13560	COG0228	four-way junction DNA binding
CAL14_RS13565	COG0425	Belongs to the sulfur carrier protein TusA family
CAL14_RS13570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CAL14_RS13620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS13630	COG2076	Multidrug Resistance protein
CAL14_RS13635	COG3217	Mosc domain protein beta barrel domain protein
CAL14_RS13635	COG0633	Ferredoxin
CAL14_RS13640	COG5285	phytanoyl-CoA dioxygenase
CAL14_RS13645	COG0662	Cupin 2, conserved barrel domain protein
CAL14_RS13655	COG0456	acetyltransferase
CAL14_RS13675	COG3118	belongs to the thioredoxin family
CAL14_RS13680	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CAL14_RS13690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CAL14_RS13695	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAL14_RS13700	COG0028	Belongs to the TPP enzyme family
CAL14_RS13705	COG0542	response to heat
CAL14_RS13710	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CAL14_RS13750	COG1174	glycine betaine transport
CAL14_RS13775	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CAL14_RS13790	COG0642	Histidine kinase
CAL14_RS13795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL14_RS13800	COG4942	peptidase
CAL14_RS13820	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAL14_RS13825	COG0842	Transport permease protein
CAL14_RS13830	COG1131	(ABC) transporter
CAL14_RS13835	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL14_RS13835	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL14_RS13840	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAL14_RS13855	COG0736	holo-[acyl-carrier-protein] synthase activity
CAL14_RS13860	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CAL14_RS13865	COG0745	RESPONSE REGULATOR receiver
CAL14_RS13880	COG4120	Belongs to the binding-protein-dependent transport system permease family
CAL14_RS13900	COG0318	PFAM AMP-dependent synthetase and ligase
CAL14_RS13905	COG1024	Enoyl-CoA hydratase
CAL14_RS13915	COG1802	Transcriptional regulator
CAL14_RS13925	COG0183	Belongs to the thiolase family
CAL14_RS13935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL14_RS13940	COG2814	Major facilitator Superfamily
CAL14_RS13945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CAL14_RS13950	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAL14_RS13965	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS13975	COG1802	Transcriptional regulator
CAL14_RS13990	COG2814	Major facilitator Superfamily
CAL14_RS13995	COG0495	leucyl-tRNA aminoacylation
CAL14_RS14010	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAL14_RS14015	COG1981	membrane
CAL14_RS14025	COG1984	allophanate hydrolase subunit 2
CAL14_RS14030	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAL14_RS14045	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL14_RS14065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL14_RS14075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CAL14_RS14090	COG0148	phosphopyruvate hydratase activity
CAL14_RS14095	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CAL14_RS14100	COG0504	CTP synthase activity
CAL14_RS14105	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS14135	COG0747	negative chemotaxis
CAL14_RS14140	COG4172	Belongs to the ABC transporter superfamily
CAL14_RS14145	COG1446	asparaginase
CAL14_RS14155	COG0392	lysyltransferase activity
CAL14_RS14160	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL14_RS14165	COG3568	Endonuclease Exonuclease Phosphatase
CAL14_RS14200	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CAL14_RS14205	COG0697	spore germination
CAL14_RS14210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL14_RS14215	COG3938	Belongs to the proline racemase family
CAL14_RS14225	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CAL14_RS14235	COG0791	NLP P60 protein
CAL14_RS14245	COG0583	DNA-binding transcription factor activity
CAL14_RS14295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAL14_RS14325	COG1381	Involved in DNA repair and RecF pathway recombination
CAL14_RS14330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAL14_RS14335	COG0571	ribonuclease III activity
CAL14_RS14340	COG0681	Belongs to the peptidase S26 family
CAL14_RS14345	COG0481	GTPase activity
CAL14_RS14350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL14_RS14375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAL14_RS14380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL14_RS14385	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS14395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAL14_RS14405	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CAL14_RS14415	COG0424	maF-like protein
CAL14_RS14425	COG3023	N-Acetylmuramoyl-L-alanine amidase
CAL14_RS14430	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CAL14_RS14435	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAL14_RS14445	COG0564	pseudouridine synthase activity
CAL14_RS14450	COG1530	ribonuclease E activity
CAL14_RS14455	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CAL14_RS14460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CAL14_RS14465	COG0159	tryptophan synthase activity
CAL14_RS14475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL14_RS14480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL14_RS14485	COG3228	Belongs to the MtfA family
CAL14_RS14490	COG0251	oxidation-reduction process
CAL14_RS14500	COG0010	Belongs to the arginase family
CAL14_RS14510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CAL14_RS14520	COG0765	amino acid transport
CAL14_RS14525	COG0765	amino acid transport
CAL14_RS14530	COG4598	ABC transporter
CAL14_RS14535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL14_RS14545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CAL14_RS14550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL14_RS14560	COG2878	Part of a membrane complex involved in electron transport
CAL14_RS14565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAL14_RS14605	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAL14_RS14610	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS14625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAL14_RS14640	COG4172	Belongs to the ABC transporter superfamily
CAL14_RS14645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS14650	COG0601	transmembrane transport
CAL14_RS14665	COG0598	Magnesium transport protein CorA
CAL14_RS14680	COG0210	DNA helicase
CAL14_RS14710	COG0483	inositol monophosphate 1-phosphatase activity
CAL14_RS14715	COG1045	serine acetyltransferase
CAL14_RS14720	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAL14_RS14725	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS14745	COG0183	Belongs to the thiolase family
CAL14_RS14755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL14_RS14760	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS14775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAL14_RS14785	COG0489	protein tyrosine kinase activity
CAL14_RS14785	COG3206	protein involved in exopolysaccharide biosynthesis
CAL14_RS14795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAL14_RS14800	COG1051	belongs to the nudix hydrolase family
CAL14_RS14805	COG0662	Cupin 2, conserved barrel domain protein
CAL14_RS14805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CAL14_RS14810	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CAL14_RS14815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL14_RS14835	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS14845	COG0110	maltose O-acetyltransferase activity
CAL14_RS14850	COG0297	glycogen (starch) synthase activity
CAL14_RS14855	COG2197	response regulator
CAL14_RS14870	COG5002	protein histidine kinase activity
CAL14_RS14875	COG0745	RESPONSE REGULATOR receiver
CAL14_RS14880	COG2814	Major facilitator Superfamily
CAL14_RS14885	COG4221	oxidoreductase activity
CAL14_RS14910	COG0583	DNA-binding transcription factor activity
CAL14_RS14925	COG1053	succinate dehydrogenase
CAL14_RS14940	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS14970	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL14_RS15000	COG0037	tRNA processing
CAL14_RS15005	COG0825	malonyl-CoA metabolic process
CAL14_RS15015	COG0215	cysteine-tRNA ligase activity
CAL14_RS15025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAL14_RS15030	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL14_RS15035	COG1968	undecaprenyl-diphosphatase activity
CAL14_RS15040	COG1253	flavin adenine dinucleotide binding
CAL14_RS15045	COG0483	inositol monophosphate 1-phosphatase activity
CAL14_RS15065	COG0668	transmembrane transport
CAL14_RS15080	COG3360	Dodecin
CAL14_RS15095	COG0477	Major facilitator Superfamily
CAL14_RS15110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CAL14_RS15115	COG2850	peptidyl-arginine hydroxylation
CAL14_RS15135	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CAL14_RS15140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL14_RS15145	COG1994	Peptidase M50
CAL14_RS15150	COG0009	L-threonylcarbamoyladenylate synthase
CAL14_RS15155	COG2321	neutral zinc metallopeptidase
CAL14_RS15160	COG0494	nUDIX hydrolase
CAL14_RS15195	COG0697	spore germination
CAL14_RS15225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL14_RS15230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL14_RS15235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS15240	COG1116	anion transmembrane transporter activity
CAL14_RS15245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL14_RS15250	COG0243	molybdopterin cofactor binding
CAL14_RS15275	COG0387	Pfam Sodium calcium exchanger
CAL14_RS15315	COG3546	catalase activity
CAL14_RS15320	COG3685	Protein conserved in bacteria
CAL14_RS15325	COG3685	Protein conserved in bacteria
CAL14_RS15330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS15350	COG1177	transmembrane transport
CAL14_RS15355	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL14_RS15360	COG3842	ATPase activity
CAL14_RS15385	COG0477	Major facilitator Superfamily
CAL14_RS15390	COG0477	Major facilitator Superfamily
CAL14_RS15400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL14_RS15440	COG1802	Transcriptional regulator
CAL14_RS15455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL14_RS15465	COG0583	DNA-binding transcription factor activity
CAL14_RS15470	COG0385	Bile acid
CAL14_RS15475	COG0596	Alpha beta hydrolase
CAL14_RS15480	COG0456	acetyltransferase
CAL14_RS15485	COG1609	Transcriptional regulator
CAL14_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS15500	COG1175	transmembrane transport
CAL14_RS15510	COG1063	alcohol dehydrogenase
CAL14_RS15515	COG3842	ATPase activity
CAL14_RS15520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAL14_RS15530	COG2146	nitrite reductase [NAD(P)H] activity
CAL14_RS15530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL14_RS15535	COG2146	nitrite reductase [NAD(P)H] activity
CAL14_RS15535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL14_RS15540	COG3707	response regulator
CAL14_RS15545	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL14_RS15565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAL14_RS15590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CAL14_RS15615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL14_RS15630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAL14_RS15635	COG2233	PERMEase
CAL14_RS15640	COG0406	alpha-ribazole phosphatase activity
CAL14_RS15645	COG0300	oxidoreductase activity
CAL14_RS15655	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAL14_RS15660	COG0505	Belongs to the CarA family
CAL14_RS15670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS15680	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL14_RS15685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS15690	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAL14_RS15700	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CAL14_RS15735	COG1686	Belongs to the peptidase S11 family
CAL14_RS15745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL14_RS15750	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS15760	COG0114	fumarate hydratase activity
CAL14_RS15770	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAL14_RS15775	COG0586	Pfam SNARE associated Golgi protein
CAL14_RS15780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAL14_RS15785	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CAL14_RS15790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAL14_RS15805	COG0617	tRNA 3'-terminal CCA addition
CAL14_RS15820	COG1024	Enoyl-CoA hydratase
CAL14_RS15825	COG0752	glycyl-tRNA synthetase alpha subunit
CAL14_RS15830	COG0751	glycine-tRNA ligase activity
CAL14_RS15835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL14_RS15840	COG0204	Acyl-transferase
CAL14_RS15860	COG0242	peptide deformylase activity
CAL14_RS15865	COG0700	Nucleoside recognition
CAL14_RS15870	COG0469	pyruvate kinase activity
CAL14_RS15875	COG1929	Belongs to the glycerate kinase type-1 family
CAL14_RS15880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CAL14_RS15885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL14_RS15900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CAL14_RS15910	COG3038	cytochrome b561
CAL14_RS15915	COG0484	heat shock protein binding
CAL14_RS15920	COG0443	Heat shock 70 kDa protein
CAL14_RS15930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAL14_RS15935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAL14_RS15940	COG1420	regulation of RNA biosynthetic process
CAL14_RS15950	COG0497	DNA recombination
CAL14_RS15955	COG0735	belongs to the Fur family
CAL14_RS15960	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL14_RS15970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAL14_RS15990	COG5265	(ABC) transporter
CAL14_RS16035	COG0387	Pfam Sodium calcium exchanger
CAL14_RS16065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CAL14_RS16070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CAL14_RS16075	COG0167	dihydroorotate dehydrogenase activity
CAL14_RS16095	COG1414	Transcriptional regulator
CAL14_RS16100	COG1546	Belongs to the CinA family
CAL14_RS16100	COG1058	Belongs to the CinA family
CAL14_RS16115	COG0513	Belongs to the DEAD box helicase family
CAL14_RS16165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL14_RS16180	COG0006	proline dipeptidase activity
CAL14_RS16190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL14_RS16215	COG0632	four-way junction helicase activity
CAL14_RS16220	COG1090	epimerase
CAL14_RS16230	COG2255	four-way junction helicase activity
CAL14_RS16235	COG0514	ATP-dependent DNA helicase (RecQ)
CAL14_RS16270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL14_RS16285	COG0850	regulation of cytokinetic process
CAL14_RS16290	COG2894	cell division
CAL14_RS16295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CAL14_RS16305	COG0488	(ABC) transporter
CAL14_RS16330	COG0583	DNA-binding transcription factor activity
CAL14_RS16345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAL14_RS16360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAL14_RS16370	COG0745	RESPONSE REGULATOR receiver
CAL14_RS16375	COG2205	protein histidine kinase activity
CAL14_RS16390	COG0259	pyridoxamine-phosphate oxidase activity
CAL14_RS16400	COG0579	oxidoreductase
CAL14_RS16410	COG1126	abc transporter atp-binding protein
CAL14_RS16415	COG0765	amino acid transport
CAL14_RS16420	COG0765	amino acid transport
CAL14_RS16435	COG0028	Belongs to the TPP enzyme family
CAL14_RS16440	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS16450	COG2030	dehydratase
CAL14_RS16455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS16460	COG0009	L-threonylcarbamoyladenylate synthase
CAL14_RS16465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CAL14_RS16470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CAL14_RS16480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CAL14_RS16510	COG2199	diguanylate cyclase activity
CAL14_RS16525	COG3454	Phosphonate metabolism
CAL14_RS16530	COG4778	phosphonate C-P lyase system protein PhnL
CAL14_RS16535	COG4107	phosphonate C-P lyase system protein PhnK
CAL14_RS16540	COG3627	carbon phosphorus lyase activity
CAL14_RS16545	COG3626	phosphonate metabolism
CAL14_RS16550	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CAL14_RS16555	COG3624	Phosphonate C-P lyase system protein PhnG
CAL14_RS16560	COG2188	Transcriptional regulator
CAL14_RS16565	COG3454	Phosphonate metabolism
CAL14_RS16570	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CAL14_RS16575	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CAL14_RS16585	COG3639	organic phosphonate transmembrane transporter activity
CAL14_RS16590	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CAL14_RS16595	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CAL14_RS16600	COG2755	lipolytic protein G-D-S-L family
CAL14_RS16600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAL14_RS16615	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAL14_RS16635	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL14_RS16640	COG0484	heat shock protein binding
CAL14_RS16660	COG0625	glutathione transferase activity
CAL14_RS16665	COG0126	phosphoglycerate kinase activity
CAL14_RS16670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAL14_RS16675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CAL14_RS16680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAL14_RS16690	COG0281	malic enzyme
CAL14_RS16690	COG0280	phosphate acetyltransferase
CAL14_RS16700	COG0436	Aminotransferase
CAL14_RS16705	COG0741	lytic transglycosylase activity
CAL14_RS16710	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CAL14_RS16725	COG4575	ribosome binding
CAL14_RS16735	COG1648	precorrin-2 dehydrogenase activity
CAL14_RS16735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAL14_RS16740	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAL14_RS16750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CAL14_RS16755	COG0343	queuine tRNA-ribosyltransferase activity
CAL14_RS16760	COG1862	Preprotein translocase
CAL14_RS16770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL14_RS16785	COG3665	Urea carboxylase-associated protein
CAL14_RS16800	COG0765	amino acid transport
CAL14_RS16805	COG0765	amino acid transport
CAL14_RS16810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS16835	COG0583	DNA-binding transcription factor activity
CAL14_RS16840	COG0583	DNA-binding transcription factor activity
CAL14_RS16860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAL14_RS16870	COG3842	ATPase activity
CAL14_RS16875	COG0395	ABC-type sugar transport system, permease component
CAL14_RS16880	COG1175	transmembrane transport
CAL14_RS16890	COG1609	Transcriptional regulator
CAL14_RS16900	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS16905	COG0318	PFAM AMP-dependent synthetase and ligase
CAL14_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS16930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL14_RS16935	COG1702	phosphate starvation-inducible protein PhoH
CAL14_RS16940	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAL14_RS16945	COG4535	Mg2 and Co2 transporter CorC
CAL14_RS16950	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CAL14_RS16955	COG0667	Aldo Keto reductase
CAL14_RS17115	COG0678	peroxiredoxin activity
CAL14_RS17125	COG0315	cyclic pyranopterin monophosphate synthase activity
CAL14_RS17135	COG0314	molybdopterin synthase activity
CAL14_RS17140	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL14_RS17145	COG0303	'Molybdopterin
CAL14_RS17150	COG0746	molybdenum cofactor guanylyltransferase activity
CAL14_RS17155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAL14_RS17175	COG3383	formate dehydrogenase (NAD+) activity
CAL14_RS17180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAL14_RS17190	COG2223	nitrite transmembrane transporter activity
CAL14_RS17205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS17210	COG0697	spore germination
CAL14_RS17235	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL14_RS17240	COG0463	Glycosyl transferase, family 2
CAL14_RS17255	COG0277	FAD linked oxidase domain protein
CAL14_RS17260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL14_RS17275	COG0583	DNA-binding transcription factor activity
CAL14_RS17300	COG1012	belongs to the aldehyde dehydrogenase family
CAL14_RS17325	COG1414	Transcriptional regulator
CAL14_RS17330	COG1418	mRNA catabolic process
CAL14_RS17340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAL14_RS17345	COG0328	RNA-DNA hybrid ribonuclease activity
CAL14_RS17350	COG2226	methyltransferase
CAL14_RS17355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL14_RS17360	COG0741	lytic transglycosylase activity
CAL14_RS17360	COG1388	LysM domain
CAL14_RS17385	COG0667	Aldo Keto reductase
CAL14_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS17395	COG1309	transcriptional regulator
CAL14_RS17400	COG0640	Transcriptional regulator
CAL14_RS17410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL14_RS17415	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL14_RS17420	COG2080	2 iron, 2 sulfur cluster binding
CAL14_RS17450	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL14_RS17455	COG0165	Argininosuccinate lyase
CAL14_RS17475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL14_RS17495	COG0402	S-adenosylhomocysteine deaminase activity
CAL14_RS17535	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS17535	COG4641	Protein conserved in bacteria
CAL14_RS17565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS17570	COG0601	transmembrane transport
CAL14_RS17585	COG2719	SpoVR family
CAL14_RS17590	COG2718	Belongs to the UPF0229 family
CAL14_RS17595	COG2766	serine protein kinase
CAL14_RS17605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL14_RS17605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL14_RS17610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAL14_RS17615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAL14_RS17620	COG1881	PFAM PEBP family protein
CAL14_RS17625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAL14_RS17630	COG0739	heme binding
CAL14_RS17635	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CAL14_RS17640	COG0316	Belongs to the HesB IscA family
CAL14_RS17650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAL14_RS17655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAL14_RS17660	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CAL14_RS17715	COG0312	modulator of DNA gyrase
CAL14_RS17720	COG3028	Belongs to the UPF0307 family
CAL14_RS17735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL14_RS17750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAL14_RS17760	COG0762	integral membrane protein
CAL14_RS17770	COG1473	amidohydrolase
CAL14_RS17775	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS17785	COG3133	Outer membrane lipoprotein
CAL14_RS17790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAL14_RS17800	COG2264	protein methyltransferase activity
CAL14_RS17805	COG0439	Biotin carboxylase
CAL14_RS17810	COG0511	ligase activity, forming carbon-carbon bonds
CAL14_RS17815	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAL14_RS17820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL14_RS17825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAL14_RS17830	COG3150	esterase
CAL14_RS17835	COG0557	exoribonuclease II activity
CAL14_RS17860	COG3842	ATPase activity
CAL14_RS17870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL14_RS17875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAL14_RS17885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL14_RS17895	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAL14_RS17900	COG1678	Uncharacterized ACR, COG1678
CAL14_RS17910	COG0351	phosphomethylpyrimidine kinase
CAL14_RS17915	COG0352	thiamine-phosphate diphosphorylase activity
CAL14_RS17920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAL14_RS17940	COG1024	Enoyl-CoA hydratase
CAL14_RS17945	COG1028	Short-chain dehydrogenase reductase Sdr
CAL14_RS17980	COG1129	ABC transporter
CAL14_RS18000	COG0657	acetylesterase activity
CAL14_RS18005	COG1846	Transcriptional regulator
CAL14_RS18015	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CAL14_RS18050	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CAL14_RS18060	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CAL14_RS18070	COG2197	response regulator
CAL14_RS18075	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAL14_RS18080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CAL14_RS18090	COG0477	Major facilitator Superfamily
CAL14_RS18105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS18110	COG3181	Tripartite tricarboxylate transporter family receptor
CAL14_RS18115	COG1280	lysine exporter protein (LysE YggA)
CAL14_RS18130	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS18150	COG0625	glutathione transferase activity
CAL14_RS18155	COG0077	Prephenate dehydratase
CAL14_RS18155	COG1605	Chorismate mutase
CAL14_RS18165	COG2081	HI0933 family
CAL14_RS18170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL14_RS18180	COG1126	abc transporter atp-binding protein
CAL14_RS18185	COG0765	amino acid transport
CAL14_RS18190	COG4597	amino acid ABC transporter
CAL14_RS18195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS18200	COG2884	Cell division ATP-binding protein ftsE
CAL14_RS18205	COG2177	Part of the ABC transporter FtsEX involved in
CAL14_RS18210	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAL14_RS18220	COG1194	a g-specific adenine glycosylase
CAL14_RS18225	COG0772	Belongs to the SEDS family
CAL14_RS18230	COG0768	penicillin binding
CAL14_RS18240	COG1792	Involved in formation and maintenance of cell shape
CAL14_RS18245	COG1077	Cell shape determining protein MreB Mrl
CAL14_RS18250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL14_RS18255	COG0154	amidase activity
CAL14_RS18260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL14_RS18265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAL14_RS18270	COG0708	Exodeoxyribonuclease III
CAL14_RS18280	COG0589	response to stress
CAL14_RS18290	COG2223	nitrite transmembrane transporter activity
CAL14_RS18295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL14_RS18295	COG2813	Specifically methylates the guanine in position
CAL14_RS18300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL14_RS18305	COG2771	luxR family
CAL14_RS18315	COG2918	glutathione biosynthetic process
CAL14_RS18320	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL14_RS18330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS18355	COG1113	amino acid transport
CAL14_RS18385	COG1674	ftsk spoiiie
CAL14_RS18400	COG0124	histidyl-tRNA synthetase
CAL14_RS18420	COG3245	cytochrome
CAL14_RS18435	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL14_RS18435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL14_RS18440	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CAL14_RS18470	COG4206	TonB-dependent receptor
CAL14_RS18475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAL14_RS18480	COG2022	thiamine diphosphate biosynthetic process
CAL14_RS18485	COG0351	phosphomethylpyrimidine kinase
CAL14_RS18490	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL14_RS18495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CAL14_RS18505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAL14_RS18525	COG2226	methyltransferase
CAL14_RS18530	COG0745	RESPONSE REGULATOR receiver
CAL14_RS18535	COG5002	protein histidine kinase activity
CAL14_RS18540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS18555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAL14_RS18560	COG1984	allophanate hydrolase subunit 2
CAL14_RS18570	COG1802	Transcriptional regulator
CAL14_RS18590	COG1238	metal cluster binding
CAL14_RS18595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL14_RS18615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS18630	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAL14_RS18635	COG0583	DNA-binding transcription factor activity
CAL14_RS18645	COG0601	transmembrane transport
CAL14_RS18650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS18655	COG0444	Belongs to the ABC transporter superfamily
CAL14_RS18660	COG4608	Belongs to the ABC transporter superfamily
CAL14_RS18680	COG0210	DNA helicase
CAL14_RS18685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAL14_RS18690	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAL14_RS18705	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAL14_RS18710	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAL14_RS18715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAL14_RS18725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAL14_RS18740	COG0356	it plays a direct role in the translocation of protons across the membrane
CAL14_RS18755	COG1024	Enoyl-CoA hydratase
CAL14_RS18760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL14_RS18765	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CAL14_RS18785	COG0163	prenyltransferase activity
CAL14_RS18790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAL14_RS18795	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL14_RS18800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAL14_RS18820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL14_RS18825	COG2818	Glycosylase
CAL14_RS18830	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CAL14_RS18835	COG1230	cation diffusion facilitator family transporter
CAL14_RS18860	COG3069	C4-dicarboxylate transmembrane transporter activity
CAL14_RS18865	COG1802	Transcriptional regulator
CAL14_RS18915	COG2943	transferase activity, transferring hexosyl groups
CAL14_RS18920	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS18925	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL14_RS18930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CAL14_RS18935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL14_RS18940	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CAL14_RS18945	COG2967	ApaG domain
CAL14_RS18950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CAL14_RS18955	COG0546	phosphoglycolate phosphatase activity
CAL14_RS18965	COG0512	Glutamine amidotransferase of anthranilate synthase
CAL14_RS18970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAL14_RS18975	COG0134	indole-3-glycerol-phosphate synthase activity
CAL14_RS18980	COG1607	acyl-coa hydrolase
CAL14_RS18990	COG3387	PFAM Glycoside hydrolase 15-related
CAL14_RS19010	COG0235	Class ii aldolase
CAL14_RS19020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL14_RS19030	COG1309	transcriptional regulator
CAL14_RS19035	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL14_RS19055	COG3604	Transcriptional regulator
CAL14_RS19060	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL14_RS19070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAL14_RS19075	COG0793	Belongs to the peptidase S41A family
CAL14_RS19080	COG4942	peptidase
CAL14_RS19085	COG0588	phosphoglycerate mutase activity
CAL14_RS19100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CAL14_RS19105	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAL14_RS19115	COG2124	cytochrome p450
CAL14_RS19125	COG1040	competence protein
CAL14_RS19130	COG2226	methyltransferase
CAL14_RS19135	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CAL14_RS19140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAL14_RS19145	COG0569	domain protein
CAL14_RS19150	COG2204	response regulator
CAL14_RS19155	COG5000	phosphorelay sensor kinase activity
CAL14_RS19165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL14_RS19175	COG2814	Major facilitator Superfamily
CAL14_RS19180	COG2944	sequence-specific DNA binding
CAL14_RS19185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL14_RS19215	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAL14_RS19220	COG0242	peptide deformylase activity
CAL14_RS19225	COG0758	DNA mediated transformation
CAL14_RS19240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL14_RS19275	COG1022	Amp-dependent synthetase and ligase
CAL14_RS19305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS19315	COG1850	ribulose-bisphosphate carboxylase activity
CAL14_RS19325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL14_RS19330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL14_RS19335	COG0583	DNA-binding transcription factor activity
CAL14_RS19345	COG0709	Synthesizes selenophosphate from selenide and ATP
CAL14_RS19360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAL14_RS19365	COG0513	Belongs to the DEAD box helicase family
CAL14_RS19385	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAL14_RS19390	COG2308	Evidence 4 Homologs of previously reported genes of
CAL14_RS19400	COG1305	Transglutaminase-like
CAL14_RS19415	COG1950	PFAM Membrane protein of
CAL14_RS19425	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS19435	COG3177	Filamentation induced by cAMP protein fic
CAL14_RS19440	COG0596	Alpha beta hydrolase
CAL14_RS19445	COG0066	3-isopropylmalate dehydratase activity
CAL14_RS19455	COG0583	DNA-binding transcription factor activity
CAL14_RS19460	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAL14_RS19470	COG1560	Kdo2-lipid A biosynthetic process
CAL14_RS19475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAL14_RS19485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CAL14_RS19495	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAL14_RS19515	COG0735	belongs to the Fur family
CAL14_RS19520	COG0523	cobalamin synthesis protein
CAL14_RS19530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CAL14_RS19535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CAL14_RS19545	COG2096	Adenosyltransferase
CAL14_RS19555	COG2080	2 iron, 2 sulfur cluster binding
CAL14_RS19560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL14_RS19565	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL14_RS19570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAL14_RS19580	COG0321	lipoyl(octanoyl) transferase activity
CAL14_RS19585	COG2921	Belongs to the UPF0250 family
CAL14_RS19595	COG1686	Belongs to the peptidase S11 family
CAL14_RS19620	COG1127	ABC transporter
CAL14_RS19625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL14_RS19635	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CAL14_RS19645	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAL14_RS19655	COG0859	PFAM glycosyl transferase family 9
CAL14_RS19695	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAL14_RS19740	COG2076	Multidrug Resistance protein
CAL14_RS19750	COG1216	Glycosyl transferase, family 2
CAL14_RS19750	COG0438	transferase activity, transferring glycosyl groups
CAL14_RS19780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL14_RS19795	COG0183	Belongs to the thiolase family
CAL14_RS19800	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL14_RS19800	COG1024	Enoyl-CoA hydratase
CAL14_RS19805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL14_RS19815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAL14_RS19835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS19845	COG2188	Transcriptional regulator
CAL14_RS19850	COG2301	Belongs to the HpcH HpaI aldolase family
CAL14_RS19855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL14_RS19870	COG1137	ATPase activity
CAL14_RS19885	COG2301	Belongs to the HpcH HpaI aldolase family
CAL14_RS19900	COG0683	leucine binding
CAL14_RS19925	COG3473	Maleate cis-trans isomerase
CAL14_RS19930	COG0596	Alpha beta hydrolase
CAL14_RS19935	COG2309	aminopeptidase activity
CAL14_RS19940	COG1335	isochorismatase
CAL14_RS19945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL14_RS19970	COG1956	GAF domain-containing protein
CAL14_RS19975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL14_RS19990	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CAL14_RS20000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL14_RS20015	COG1177	transmembrane transport
CAL14_RS20020	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL14_RS20025	COG3842	ATPase activity
CAL14_RS20045	COG2814	Major facilitator Superfamily
CAL14_RS20060	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CAL14_RS20065	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CAL14_RS20070	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL14_RS20080	COG1965	Belongs to the frataxin family
CAL14_RS20095	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAL14_RS20100	COG1333	cytochrome c biogenesis protein
CAL14_RS20110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAL14_RS20125	COG3547	Transposase (IS116 IS110 IS902 family)
CAL14_RS20135	COG4232	protein-disulfide reductase activity
CAL14_RS20140	COG1324	tolerance protein
CAL14_RS20145	COG0203	ribosomal protein L17
CAL14_RS20150	COG0202	RNA polymerase activity
CAL14_RS20155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CAL14_RS20160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAL14_RS20165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAL14_RS20170	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAL14_RS20180	COG0201	protein transport
CAL14_RS20185	COG0200	Binds to the 23S rRNA
CAL14_RS20190	COG1841	ribosomal large subunit assembly
CAL14_RS20195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CAL14_RS20200	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAL14_RS20205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAL14_RS20210	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CAL14_RS20215	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CAL14_RS20220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAL14_RS20225	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CAL14_RS20230	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CAL14_RS20255	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAL14_RS20260	COG0255	Belongs to the universal ribosomal protein uL29 family
CAL14_RS20265	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAL14_RS20270	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAL14_RS20275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CAL14_RS20280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAL14_RS20285	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAL14_RS20290	COG0089	rRNA binding
CAL14_RS20300	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAL14_RS20305	COG0051	transcription antitermination factor activity, RNA binding
CAL14_RS20310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL14_RS20315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL14_RS20320	COG0049	tRNA binding
CAL14_RS20325	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAL14_RS20375	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAL14_RS20380	COG0085	RNA polymerase activity
CAL14_RS20385	COG0222	ribosome binding
CAL14_RS20390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAL14_RS20395	COG0081	regulation of translation
CAL14_RS20400	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAL14_RS20410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL14_RS20420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL14_RS20445	COG0252	asparaginase activity
CAL14_RS20450	COG1475	DNA binding
CAL14_RS20460	COG1192	Involved in chromosome partitioning
CAL14_RS20465	COG0357	Ribosomal RNA small subunit methyltransferase G
CAL14_RS20470	COG0445	tRNA wobble uridine modification
CAL14_RS20475	COG1278	Cold shock
CAL14_RS20480	COG0436	Aminotransferase
CAL14_RS20485	COG1595	DNA-templated transcription, initiation
CAL14_RS20490	COG3712	iron ion homeostasis
CAL14_RS20495	COG4774	siderophore transport
CAL14_RS20515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CAL14_RS20525	COG0601	transmembrane transport
CAL14_RS20530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL14_RS20535	COG0444	Belongs to the ABC transporter superfamily
CAL14_RS20540	COG4608	Belongs to the ABC transporter superfamily
CAL14_RS20550	COG1473	amidohydrolase
CAL14_RS20560	COG1960	acyl-CoA dehydrogenase activity
CAL14_RS20580	COG0583	DNA-binding transcription factor activity
CAL14_RS20585	COG0706	membrane insertase activity
CAL14_RS20590	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAL14_RS20595	COG0594	ribonuclease P activity
CAL14_RS20600	COG0230	Belongs to the bacterial ribosomal protein bL34 family