locus-tag	class	description
CAL13_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CAL13_RS00020	COG0583	DNA-binding transcription factor activity
CAL13_RS00030	COG2175	clavaminate synthase activity
CAL13_RS00075	COG1573	uracil-dna glycosylase
CAL13_RS00100	COG0657	acetylesterase activity
CAL13_RS00115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL13_RS00130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CAL13_RS00140	COG1522	sequence-specific DNA binding
CAL13_RS00145	COG0028	Belongs to the TPP enzyme family
CAL13_RS00150	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS00155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CAL13_RS00155	COG0551	DNA topoisomerase type I activity
CAL13_RS00165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL13_RS00170	COG2922	Belongs to the Smg family
CAL13_RS00180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CAL13_RS00195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CAL13_RS00200	COG0183	Belongs to the thiolase family
CAL13_RS00205	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS00215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL13_RS00220	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS00240	COG0018	arginyl-trna synthetase
CAL13_RS00260	COG0154	amidase activity
CAL13_RS00265	COG1609	Transcriptional regulator
CAL13_RS00270	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL13_RS00280	COG1177	transmembrane transport
CAL13_RS00285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL13_RS00290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL13_RS00300	COG1653	transport
CAL13_RS00305	COG1175	transmembrane transport
CAL13_RS00310	COG0395	ABC-type sugar transport system, permease component
CAL13_RS00315	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL13_RS00325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL13_RS00350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CAL13_RS00355	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS00360	COG0513	Belongs to the DEAD box helicase family
CAL13_RS00410	COG0625	glutathione transferase activity
CAL13_RS00415	COG2857	Cytochrome c1
CAL13_RS00420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CAL13_RS00425	COG0723	plastoquinol--plastocyanin reductase activity
CAL13_RS00430	COG1970	mechanosensitive ion channel activity
CAL13_RS00435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CAL13_RS00440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL13_RS00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL13_RS00460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CAL13_RS00465	COG0537	adenosine 5'-monophosphoramidase activity
CAL13_RS00470	COG0140	phosphoribosyl-ATP diphosphatase activity
CAL13_RS00480	COG0107	imidazoleglycerol-phosphate synthase activity
CAL13_RS00485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CAL13_RS00495	COG0131	Imidazoleglycerol-phosphate dehydratase
CAL13_RS00500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL13_RS00505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CAL13_RS00510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CAL13_RS00515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CAL13_RS00525	COG0842	Transport permease protein
CAL13_RS00530	COG1131	(ABC) transporter
CAL13_RS00540	COG2853	Lipoprotein
CAL13_RS00545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL13_RS00550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL13_RS00555	COG1127	ABC transporter
CAL13_RS00565	COG2059	Chromate
CAL13_RS00575	COG0069	glutamate synthase activity
CAL13_RS00575	COG0070	glutamate synthase
CAL13_RS00575	COG0067	glutamate synthase
CAL13_RS00605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CAL13_RS00620	COG0747	negative chemotaxis
CAL13_RS00625	COG1609	Transcriptional regulator
CAL13_RS00630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL13_RS00635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS00640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL13_RS00645	COG0129	dihydroxy-acid dehydratase activity
CAL13_RS00650	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CAL13_RS00660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL13_RS00700	COG1999	signal sequence binding
CAL13_RS00730	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CAL13_RS00735	COG2814	Major facilitator Superfamily
CAL13_RS00750	COG1522	sequence-specific DNA binding
CAL13_RS00780	COG0477	Major facilitator Superfamily
CAL13_RS00795	COG0066	3-isopropylmalate dehydratase activity
CAL13_RS00800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CAL13_RS00805	COG2188	Transcriptional regulator
CAL13_RS00815	COG2814	Major facilitator Superfamily
CAL13_RS00820	COG4977	sequence-specific DNA binding
CAL13_RS00825	COG1304	FMN binding
CAL13_RS00830	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS00850	COG1396	sequence-specific DNA binding
CAL13_RS00855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS00860	COG0765	amino acid transport
CAL13_RS00865	COG1126	abc transporter atp-binding protein
CAL13_RS00870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS00875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL13_RS00905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS00925	COG1414	Transcriptional regulator
CAL13_RS00940	COG2358	TRAP transporter, solute receptor (TAXI family
CAL13_RS00945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CAL13_RS00950	COG1074	ATP-dependent DNA helicase activity
CAL13_RS00955	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CAL13_RS00965	COG0784	Response regulator, receiver
CAL13_RS00965	COG4191	Histidine kinase
CAL13_RS01000	COG1666	GTP binding
CAL13_RS01010	COG0300	oxidoreductase activity
CAL13_RS01015	COG2207	Transcriptional regulator
CAL13_RS01020	COG4208	sulfate ABC transporter
CAL13_RS01025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL13_RS01035	COG2816	NAD+ diphosphatase activity
CAL13_RS01040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL13_RS01045	COG2823	Periplasmic or secreted lipoprotein
CAL13_RS01050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CAL13_RS01055	COG0792	nuclease activity
CAL13_RS01070	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CAL13_RS01075	COG1660	Displays ATPase and GTPase activities
CAL13_RS01090	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CAL13_RS01100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CAL13_RS01105	COG1137	ATPase activity
CAL13_RS01130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CAL13_RS01135	COG0747	negative chemotaxis
CAL13_RS01160	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL13_RS01165	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CAL13_RS01170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CAL13_RS01175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CAL13_RS01180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CAL13_RS01185	COG0142	geranyltranstransferase activity
CAL13_RS01195	COG4106	trans-aconitate 2-methyltransferase activity
CAL13_RS01205	COG3403	YqcI/YcgG family
CAL13_RS01240	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL13_RS01250	COG1414	Transcriptional regulator
CAL13_RS01255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CAL13_RS01265	COG0129	dihydroxy-acid dehydratase activity
CAL13_RS01270	COG2814	Major facilitator Superfamily
CAL13_RS01280	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CAL13_RS01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL13_RS01305	COG0583	DNA-binding transcription factor activity
CAL13_RS01320	COG0058	SHG alpha-glucan phosphorylase activity
CAL13_RS01335	COG0420	3'-5' exonuclease activity
CAL13_RS01400	COG0326	Molecular chaperone. Has ATPase activity
CAL13_RS01405	COG1396	sequence-specific DNA binding
CAL13_RS01415	COG2271	Major facilitator Superfamily
CAL13_RS01420	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS01425	COG0800	Aldolase
CAL13_RS01430	COG3734	2-keto-3-deoxy-galactonokinase
CAL13_RS01435	COG1414	Transcriptional regulator
CAL13_RS01455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CAL13_RS01470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CAL13_RS01480	COG0582	viral genome integration into host DNA
CAL13_RS01500	COG3634	alkyl hydroperoxide reductase activity
CAL13_RS01570	COG2207	Transcriptional regulator
CAL13_RS01575	COG0066	3-isopropylmalate dehydratase activity
CAL13_RS01585	COG0596	Alpha beta hydrolase
CAL13_RS01590	COG0583	DNA-binding transcription factor activity
CAL13_RS01605	COG0583	DNA-binding transcription factor activity
CAL13_RS01610	COG2267	carboxylic ester hydrolase activity
CAL13_RS01615	COG0024	Methionine aminopeptidase
CAL13_RS01630	COG0583	DNA-binding transcription factor activity
CAL13_RS01660	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CAL13_RS01670	COG1846	Transcriptional regulator
CAL13_RS01680	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS01685	COG0596	Alpha beta hydrolase
CAL13_RS01690	COG2267	carboxylic ester hydrolase activity
CAL13_RS01715	COG2814	Major facilitator Superfamily
CAL13_RS01725	COG0583	DNA-binding transcription factor activity
CAL13_RS01755	COG0464	growth
CAL13_RS01775	COG4251	negative regulation of phosphorylation
CAL13_RS01775	COG5001	Diguanylate cyclase
CAL13_RS01775	COG3706	GGDEF domain
CAL13_RS01775	COG2203	Gaf domain
CAL13_RS01780	COG1569	PIN domain
CAL13_RS01785	COG3311	Transcriptional regulator
CAL13_RS01810	COG2205	protein histidine kinase activity
CAL13_RS01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS01815	COG2197	response regulator
CAL13_RS01835	COG0786	glutamate:sodium symporter activity
CAL13_RS01840	COG3469	chitinase activity
CAL13_RS01870	COG2197	response regulator
CAL13_RS01900	COG3300	MHYT domain
CAL13_RS01900	COG5001	Diguanylate cyclase
CAL13_RS01955	COG3451	type IV secretory pathway VirB4
CAL13_RS01970	COG3846	protein secretion by the type IV secretion system
CAL13_RS02080	COG3077	Addiction module antitoxin, RelB DinJ family
CAL13_RS02155	COG1116	anion transmembrane transporter activity
CAL13_RS02160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS02170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL13_RS02175	COG0583	DNA-binding transcription factor activity
CAL13_RS02180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CAL13_RS02190	COG0277	FAD linked oxidase domain protein
CAL13_RS02190	COG0247	lactate metabolic process
CAL13_RS02195	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS02210	COG1024	Enoyl-CoA hydratase
CAL13_RS02215	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS02225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL13_RS02250	COG4774	siderophore transport
CAL13_RS02255	COG3712	iron ion homeostasis
CAL13_RS02260	COG1595	DNA-templated transcription, initiation
CAL13_RS02265	COG0625	glutathione transferase activity
CAL13_RS02280	COG2264	protein methyltransferase activity
CAL13_RS02285	COG0531	amino acid
CAL13_RS02310	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS02320	COG0583	DNA-binding transcription factor activity
CAL13_RS02335	COG1054	Belongs to the UPF0176 family
CAL13_RS02370	COG0717	Belongs to the dCTP deaminase family
CAL13_RS02385	COG2081	HI0933 family
CAL13_RS02395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CAL13_RS02400	COG0509	glycine decarboxylation via glycine cleavage system
CAL13_RS02405	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL13_RS02405	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CAL13_RS02425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL13_RS02430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS02445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CAL13_RS02460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CAL13_RS02475	COG0277	FAD linked oxidase domain protein
CAL13_RS02480	COG0745	RESPONSE REGULATOR receiver
CAL13_RS02495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CAL13_RS02495	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS02505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL13_RS02510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL13_RS02515	COG2186	Transcriptional regulator
CAL13_RS02520	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL13_RS02525	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CAL13_RS02535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CAL13_RS02545	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CAL13_RS02550	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CAL13_RS02560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CAL13_RS02570	COG0193	aminoacyl-tRNA hydrolase activity
CAL13_RS02585	COG0012	GTP binding
CAL13_RS02590	COG2814	Major facilitator Superfamily
CAL13_RS02600	COG0842	Transport permease protein
CAL13_RS02605	COG0842	Transport permease protein
CAL13_RS02610	COG1131	(ABC) transporter
CAL13_RS02635	COG3135	benzoate transporter
CAL13_RS02640	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CAL13_RS02645	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CAL13_RS02650	COG0742	ribosomal rna small subunit methyltransferase
CAL13_RS02660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CAL13_RS02675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CAL13_RS02680	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL13_RS02685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CAL13_RS02695	COG1546	Belongs to the CinA family
CAL13_RS02700	COG0284	orotidine-5'-phosphate decarboxylase activity
CAL13_RS02705	COG1252	NADH dehydrogenase
CAL13_RS02720	COG1063	alcohol dehydrogenase
CAL13_RS02725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL13_RS02735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS02740	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS02745	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL13_RS02750	COG2721	sulfolactate sulfo-lyase activity
CAL13_RS02755	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS02760	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL13_RS02765	COG1289	transmembrane transporter activity
CAL13_RS02770	COG1959	2 iron, 2 sulfur cluster binding
CAL13_RS02770	COG1295	ribonuclease BN
CAL13_RS02780	COG0459	protein refolding
CAL13_RS02785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL13_RS02845	COG0667	Aldo Keto reductase
CAL13_RS02870	COG0583	DNA-binding transcription factor activity
CAL13_RS02875	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS02895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS02900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL13_RS02915	COG3386	PFAM SMP-30 Gluconolaconase
CAL13_RS02945	COG3744	PilT protein domain protein
CAL13_RS02980	COG4774	siderophore transport
CAL13_RS02985	COG0628	permease
CAL13_RS03000	COG1802	Transcriptional regulator
CAL13_RS03010	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS03030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL13_RS03035	COG0583	DNA-binding transcription factor activity
CAL13_RS03045	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAL13_RS03060	COG0546	phosphoglycolate phosphatase activity
CAL13_RS03080	COG4691	Plasmid stability protein
CAL13_RS03095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL13_RS03095	COG1017	nitric oxide dioxygenase activity
CAL13_RS03100	COG0625	glutathione transferase activity
CAL13_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03115	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03120	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS03125	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03135	COG4172	Belongs to the ABC transporter superfamily
CAL13_RS03145	COG0318	PFAM AMP-dependent synthetase and ligase
CAL13_RS03150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS03155	COG0601	transmembrane transport
CAL13_RS03190	COG0246	Mannitol dehydrogenase
CAL13_RS03195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CAL13_RS03210	COG2188	Transcriptional regulator
CAL13_RS03240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL13_RS03250	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS03255	COG1064	alcohol dehydrogenase
CAL13_RS03260	COG2207	Transcriptional regulator
CAL13_RS03265	COG4753	response regulator
CAL13_RS03265	COG2207	Transcriptional regulator
CAL13_RS03275	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS03285	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03300	COG3842	ATPase activity
CAL13_RS03305	COG0583	DNA-binding transcription factor activity
CAL13_RS03310	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS03315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS03315	COG0473	3-isopropylmalate dehydrogenase activity
CAL13_RS03330	COG1764	response to oxidative stress
CAL13_RS03335	COG0583	DNA-binding transcription factor activity
CAL13_RS03345	COG1595	DNA-templated transcription, initiation
CAL13_RS03420	COG0765	amino acid transport
CAL13_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS03435	COG0436	Aminotransferase
CAL13_RS03440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS03450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL13_RS03455	COG0657	acetylesterase activity
CAL13_RS03495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS03510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS03515	COG0765	amino acid transport
CAL13_RS03530	COG0402	S-adenosylhomocysteine deaminase activity
CAL13_RS03540	COG3384	dioxygenase
CAL13_RS03545	COG2207	Transcriptional regulator
CAL13_RS03570	COG0583	DNA-binding transcription factor activity
CAL13_RS03575	COG1902	pentaerythritol trinitrate reductase activity
CAL13_RS03585	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03595	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS03625	COG2116	formate transmembrane transporter activity
CAL13_RS03630	COG2223	nitrite transmembrane transporter activity
CAL13_RS03655	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS03670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL13_RS03690	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL13_RS03695	COG3971	2-oxopent-4-enoate hydratase activity
CAL13_RS03720	COG1881	PFAM PEBP family protein
CAL13_RS03725	COG0583	DNA-binding transcription factor activity
CAL13_RS03730	COG0626	cystathionine gamma-synthase activity
CAL13_RS03735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS03740	COG0765	amino acid transport
CAL13_RS03745	COG0765	amino acid transport
CAL13_RS03750	COG1126	abc transporter atp-binding protein
CAL13_RS03755	COG3608	succinylglutamate desuccinylase aspartoacylase
CAL13_RS03770	COG0583	DNA-binding transcription factor activity
CAL13_RS03775	COG0477	Major facilitator Superfamily
CAL13_RS03790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS03815	COG5507	3-demethylubiquinone-9 3-methyltransferase
CAL13_RS03825	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03845	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS03860	COG0701	Predicted permease
CAL13_RS03880	COG3468	outer membrane autotransporter barrel domain protein
CAL13_RS03890	COG0531	amino acid
CAL13_RS03910	COG0583	DNA-binding transcription factor activity
CAL13_RS03925	COG0859	PFAM glycosyl transferase family 9
CAL13_RS03955	COG1902	pentaerythritol trinitrate reductase activity
CAL13_RS03960	COG4297	protein containing double-stranded beta helix domain
CAL13_RS03975	COG5265	(ABC) transporter
CAL13_RS03980	COG1295	ribonuclease BN
CAL13_RS03990	COG0129	dihydroxy-acid dehydratase activity
CAL13_RS04000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL13_RS04035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CAL13_RS04040	COG0459	protein refolding
CAL13_RS04050	COG3706	GGDEF domain
CAL13_RS04055	COG0840	transmembrane signaling receptor activity
CAL13_RS04065	COG2186	Transcriptional regulator
CAL13_RS04100	COG1132	(ABC) transporter
CAL13_RS04105	COG2155	Conserved Protein
CAL13_RS04110	COG2814	Major facilitator Superfamily
CAL13_RS04115	COG2200	EAL domain
CAL13_RS04120	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS04150	COG2733	membrane
CAL13_RS04155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CAL13_RS04160	COG0655	NAD(P)H dehydrogenase (quinone) activity
CAL13_RS04175	COG3795	YCII-related domain
CAL13_RS04190	COG4941	Belongs to the sigma-70 factor family
CAL13_RS04210	COG0783	Belongs to the Dps family
CAL13_RS04245	COG0583	DNA-binding transcription factor activity
CAL13_RS04250	COG0038	chloride channel
CAL13_RS04280	COG0463	Glycosyl transferase, family 2
CAL13_RS04290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL13_RS04300	COG0859	PFAM glycosyl transferase family 9
CAL13_RS04310	COG2192	nodulation
CAL13_RS04315	COG0859	PFAM glycosyl transferase family 9
CAL13_RS04320	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL13_RS04330	COG0297	glycogen (starch) synthase activity
CAL13_RS04335	COG5265	(ABC) transporter
CAL13_RS04350	COG0741	lytic transglycosylase activity
CAL13_RS04370	COG0477	Major facilitator Superfamily
CAL13_RS04380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS04385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS04390	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CAL13_RS04400	COG2175	clavaminate synthase activity
CAL13_RS04410	COG0583	DNA-binding transcription factor activity
CAL13_RS04415	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS04420	COG0363	glucosamine-6-phosphate deaminase activity
CAL13_RS04425	COG0561	phosphatase activity
CAL13_RS04430	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CAL13_RS04435	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
CAL13_RS04440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CAL13_RS04450	COG1940	carbohydrate kinase activity
CAL13_RS04465	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CAL13_RS04495	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL13_RS04500	COG3437	response regulator, receiver
CAL13_RS04500	COG4999	Histidine kinase
CAL13_RS04500	COG3850	Histidine kinase
CAL13_RS04500	COG2205	protein histidine kinase activity
CAL13_RS04500	COG3437	response regulator, receiver
CAL13_RS04500	COG4999	Histidine kinase
CAL13_RS04500	COG3850	Histidine kinase
CAL13_RS04500	COG2205	protein histidine kinase activity
CAL13_RS04505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS04510	COG1285	pathogenesis
CAL13_RS04515	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS04525	COG2267	carboxylic ester hydrolase activity
CAL13_RS04615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CAL13_RS04620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CAL13_RS04635	COG0823	Involved in the tonB-independent uptake of proteins
CAL13_RS04645	COG0848	biopolymer transport protein
CAL13_RS04650	COG0811	peptide transport
CAL13_RS04655	COG0824	Thioesterase
CAL13_RS04660	COG0442	prolyl-tRNA aminoacylation
CAL13_RS04675	COG0642	Histidine kinase
CAL13_RS04690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS04695	COG2084	Dehydrogenase
CAL13_RS04735	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CAL13_RS04740	COG0129	dihydroxy-acid dehydratase activity
CAL13_RS04795	COG1473	amidohydrolase
CAL13_RS04800	COG0418	dihydroorotase activity
CAL13_RS04805	COG0488	(ABC) transporter
CAL13_RS04815	COG3511	phospholipase C
CAL13_RS04825	COG2001	Belongs to the MraZ family
CAL13_RS04830	COG0275	rRNA processing
CAL13_RS04835	COG3116	cell division
CAL13_RS04850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL13_RS04855	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CAL13_RS04870	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAL13_RS04875	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAL13_RS04880	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CAL13_RS04890	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CAL13_RS04895	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CAL13_RS04905	COG0739	heme binding
CAL13_RS04910	COG0653	protein targeting
CAL13_RS04930	COG0028	Belongs to the TPP enzyme family
CAL13_RS04945	COG1522	sequence-specific DNA binding
CAL13_RS04955	COG2239	Acts as a magnesium transporter
CAL13_RS04965	COG2855	membrane
CAL13_RS04975	COG1473	amidohydrolase
CAL13_RS04980	COG0318	PFAM AMP-dependent synthetase and ligase
CAL13_RS04990	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS04990	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CAL13_RS04995	COG1501	Belongs to the glycosyl hydrolase 31 family
CAL13_RS05000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CAL13_RS05005	COG2011	ABC-type metal ion transport system permease component
CAL13_RS05030	COG2197	response regulator
CAL13_RS05040	COG0745	RESPONSE REGULATOR receiver
CAL13_RS05060	COG4789	Type iii secretion
CAL13_RS05105	COG4669	(LipO)protein
CAL13_RS05145	COG4790	Type iii secretion
CAL13_RS05150	COG4794	Type iii secretion
CAL13_RS05155	COG4791	protein targeting
CAL13_RS05160	COG4792	protein secretion
CAL13_RS05180	COG5001	Diguanylate cyclase
CAL13_RS05180	COG3300	MHYT domain
CAL13_RS05195	COG1368	sulfuric ester hydrolase activity
CAL13_RS05200	COG2982	Protein involved in outer membrane biogenesis
CAL13_RS05225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL13_RS05235	COG0457	Tetratricopeptide repeat
CAL13_RS05240	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS05265	COG1560	Kdo2-lipid A biosynthetic process
CAL13_RS05265	COG4783	chaperone-mediated protein folding
CAL13_RS05275	COG3866	Pectate lyase
CAL13_RS05280	COG0861	Integral membrane protein TerC family
CAL13_RS05285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CAL13_RS05295	COG2186	Transcriptional regulator
CAL13_RS05300	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CAL13_RS05325	COG4638	Rieske (2fe-2S)
CAL13_RS05330	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS05335	COG0028	Belongs to the TPP enzyme family
CAL13_RS05340	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS05345	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS05350	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAL13_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS05360	COG0640	Transcriptional regulator
CAL13_RS05370	COG0625	glutathione transferase activity
CAL13_RS05375	COG1126	abc transporter atp-binding protein
CAL13_RS05380	COG0765	amino acid transport
CAL13_RS05385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS05395	COG2814	Major facilitator Superfamily
CAL13_RS05400	COG0667	Aldo Keto reductase
CAL13_RS05405	COG0612	Peptidase, M16
CAL13_RS05420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL13_RS05455	COG0745	RESPONSE REGULATOR receiver
CAL13_RS05460	COG2205	protein histidine kinase activity
CAL13_RS05465	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CAL13_RS05470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CAL13_RS05475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CAL13_RS05490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CAL13_RS05500	COG1193	negative regulation of DNA recombination
CAL13_RS05505	COG0492	ferredoxin-NADP+ reductase activity
CAL13_RS05510	COG1674	ftsk spoiiie
CAL13_RS05515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CAL13_RS05525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL13_RS05550	COG0601	transmembrane transport
CAL13_RS05555	COG0747	negative chemotaxis
CAL13_RS05565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CAL13_RS05570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CAL13_RS05590	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL13_RS05605	COG2188	Transcriptional regulator
CAL13_RS05630	COG1294	oxidase, subunit
CAL13_RS05635	COG1271	oxidase subunit
CAL13_RS05645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CAL13_RS05650	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CAL13_RS05655	COG2828	Protein conserved in bacteria
CAL13_RS05660	COG2205	protein histidine kinase activity
CAL13_RS05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS05665	COG2197	response regulator
CAL13_RS05675	COG0667	Aldo Keto reductase
CAL13_RS05680	COG2207	Transcriptional regulator
CAL13_RS05685	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CAL13_RS05700	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CAL13_RS05705	COG1845	cytochrome c oxidase, subunit III
CAL13_RS05710	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL13_RS05715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL13_RS05720	COG0477	Major facilitator Superfamily
CAL13_RS05725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL13_RS05730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CAL13_RS05740	COG1252	NADH dehydrogenase
CAL13_RS05840	COG0582	viral genome integration into host DNA
CAL13_RS05850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAL13_RS05850	COG0475	glutathione-regulated potassium exporter activity
CAL13_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS05860	COG3022	response to hydroperoxide
CAL13_RS05865	COG1289	transmembrane transporter activity
CAL13_RS05870	COG0028	Belongs to the TPP enzyme family
CAL13_RS05875	COG0440	acetolactate synthase activity
CAL13_RS05880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CAL13_RS05885	COG0688	phosphatidylethanolamine metabolic process
CAL13_RS05890	COG1183	phosphatidylcholine synthase activity
CAL13_RS05900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CAL13_RS05905	COG1185	polyribonucleotide nucleotidyltransferase activity
CAL13_RS05915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL13_RS05930	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
CAL13_RS05945	COG1802	Transcriptional regulator
CAL13_RS05955	COG1024	Enoyl-CoA hydratase
CAL13_RS05960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS05965	COG1802	Transcriptional regulator
CAL13_RS05970	COG0247	lactate metabolic process
CAL13_RS05970	COG0277	FAD linked oxidase domain protein
CAL13_RS05990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CAL13_RS06010	COG0456	acetyltransferase
CAL13_RS06010	COG1846	Transcriptional regulator
CAL13_RS06015	COG0300	oxidoreductase activity
CAL13_RS06020	COG0028	Belongs to the TPP enzyme family
CAL13_RS06030	COG0149	triose-phosphate isomerase activity
CAL13_RS06035	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL13_RS06045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAL13_RS06050	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
CAL13_RS06060	COG4245	von Willebrand factor, type A
CAL13_RS06070	COG2814	Major facilitator Superfamily
CAL13_RS06075	COG3265	gluconokinase activity
CAL13_RS06080	COG0500	methyltransferase
CAL13_RS06110	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS06120	COG0668	transmembrane transport
CAL13_RS06130	COG2133	pyrroloquinoline quinone binding
CAL13_RS06140	COG0583	DNA-binding transcription factor activity
CAL13_RS06150	COG0405	Gamma-glutamyltransferase
CAL13_RS06155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL13_RS06160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL13_RS06165	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL13_RS06170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL13_RS06175	COG0649	NAD binding
CAL13_RS06180	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CAL13_RS06190	COG1034	ATP synthesis coupled electron transport
CAL13_RS06190	COG1034	ATP synthesis coupled electron transport
CAL13_RS06195	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CAL13_RS06200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CAL13_RS06210	COG0713	ATP synthesis coupled electron transport
CAL13_RS06225	COG1007	ATP synthesis coupled electron transport
CAL13_RS06240	COG4774	siderophore transport
CAL13_RS06245	COG0560	Phosphoserine phosphatase
CAL13_RS06250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CAL13_RS06255	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CAL13_RS06260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CAL13_RS06265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL13_RS06270	COG0450	alkyl hydroperoxide reductase
CAL13_RS06285	COG1214	PFAM Peptidase M22, glycoprotease
CAL13_RS06290	COG1573	uracil-dna glycosylase
CAL13_RS06295	COG0477	Major facilitator Superfamily
CAL13_RS06300	COG1196	nuclear chromosome segregation
CAL13_RS06310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CAL13_RS06315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL13_RS06325	COG2917	probably involved in intracellular septation
CAL13_RS06330	COG1122	ATPase activity
CAL13_RS06335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CAL13_RS06340	COG1268	BioY protein
CAL13_RS06375	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS06385	COG0583	DNA-binding transcription factor activity
CAL13_RS06405	COG3264	Mechanosensitive ion channel
CAL13_RS06405	COG1196	nuclear chromosome segregation
CAL13_RS06415	COG0583	DNA-binding transcription factor activity
CAL13_RS06465	COG0477	Major facilitator Superfamily
CAL13_RS06475	COG1414	Transcriptional regulator
CAL13_RS06480	COG2084	Dehydrogenase
CAL13_RS06485	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS06510	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS06515	COG4177	L-phenylalanine transmembrane transporter activity
CAL13_RS06535	COG0625	glutathione transferase activity
CAL13_RS06540	COG0625	glutathione transferase activity
CAL13_RS06550	COG2079	MmgE PrpD family protein
CAL13_RS06565	COG0039	L-malate dehydrogenase activity
CAL13_RS06570	COG2188	Transcriptional regulator
CAL13_RS06575	COG2009	succinate dehydrogenase
CAL13_RS06580	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CAL13_RS06585	COG1053	succinate dehydrogenase
CAL13_RS06590	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CAL13_RS06595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CAL13_RS06600	COG0372	Belongs to the citrate synthase family
CAL13_RS06610	COG0280	phosphate acetyltransferase
CAL13_RS06610	COG0281	malic enzyme
CAL13_RS06615	COG0567	Dehydrogenase, E1 component
CAL13_RS06620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL13_RS06625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL13_RS06630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CAL13_RS06650	COG2183	response to ionizing radiation
CAL13_RS06655	COG1199	ATP-dependent helicase activity
CAL13_RS06665	COG0564	pseudouridine synthase activity
CAL13_RS06675	COG3243	poly(R)-hydroxyalkanoic acid synthase
CAL13_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS06685	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CAL13_RS06700	COG0672	)-iron permease
CAL13_RS06715	COG2823	Periplasmic or secreted lipoprotein
CAL13_RS06725	COG1181	Belongs to the D-alanine--D-alanine ligase family
CAL13_RS06725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL13_RS06730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CAL13_RS06730	COG0189	ligase activity
CAL13_RS06735	COG1132	(ABC) transporter
CAL13_RS06745	COG0246	Mannitol dehydrogenase
CAL13_RS06750	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS06760	COG1802	Transcriptional regulator
CAL13_RS06770	COG2833	Protein of unknown function (DUF455)
CAL13_RS06780	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CAL13_RS06785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS06795	COG2721	sulfolactate sulfo-lyase activity
CAL13_RS06800	COG2721	sulfolactate sulfo-lyase activity
CAL13_RS06805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL13_RS06815	COG0494	nUDIX hydrolase
CAL13_RS06825	COG1733	regulation of RNA biosynthetic process
CAL13_RS06840	COG2814	Major facilitator Superfamily
CAL13_RS06860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CAL13_RS06880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CAL13_RS06885	COG0077	Prephenate dehydratase
CAL13_RS06885	COG1605	Chorismate mutase
CAL13_RS06890	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL13_RS06895	COG0287	Prephenate dehydrogenase
CAL13_RS06900	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CAL13_RS06905	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CAL13_RS06925	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CAL13_RS06930	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CAL13_RS06935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL13_RS06940	COG1596	polysaccharide export
CAL13_RS06940	COG1555	photosystem II stabilization
CAL13_RS06955	COG0123	including yeast histone deacetylase and acetoin utilization protein
CAL13_RS06970	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS06975	COG0450	alkyl hydroperoxide reductase
CAL13_RS06980	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CAL13_RS06985	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL13_RS06990	COG4208	sulfate ABC transporter
CAL13_RS06995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CAL13_RS07000	COG0175	sulfate reduction
CAL13_RS07025	COG0335	large ribosomal subunit rRNA binding
CAL13_RS07035	COG1162	GTPase activity
CAL13_RS07040	COG0501	Belongs to the peptidase M48B family
CAL13_RS07045	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CAL13_RS07050	COG3327	negative regulation of DNA-templated transcription, initiation
CAL13_RS07055	COG3396	Phenylacetate-CoA oxygenase
CAL13_RS07060	COG3460	Phenylacetate-CoA oxygenase
CAL13_RS07065	COG3396	Phenylacetate-CoA oxygenase
CAL13_RS07070	COG2151	metal-sulfur cluster biosynthetic enzyme
CAL13_RS07080	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS07085	COG1024	Enoyl-CoA hydratase
CAL13_RS07090	COG2050	protein possibly involved in aromatic compounds catabolism
CAL13_RS07100	COG0534	Mate efflux family protein
CAL13_RS07115	COG2003	Belongs to the UPF0758 family
CAL13_RS07125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CAL13_RS07130	COG0625	glutathione transferase activity
CAL13_RS07135	COG2721	sulfolactate sulfo-lyase activity
CAL13_RS07150	COG2188	Transcriptional regulator
CAL13_RS07160	COG0640	Transcriptional regulator
CAL13_RS07195	COG1058	Belongs to the CinA family
CAL13_RS07195	COG1546	Belongs to the CinA family
CAL13_RS07205	COG0514	ATP-dependent DNA helicase (RecQ)
CAL13_RS07265	COG2814	Major facilitator Superfamily
CAL13_RS07275	COG3622	Belongs to the hyi family
CAL13_RS07280	COG0251	oxidation-reduction process
CAL13_RS07285	COG0523	cobalamin synthesis protein
CAL13_RS07295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CAL13_RS07300	COG1187	pseudouridine synthase activity
CAL13_RS07305	COG0779	Required for maturation of 30S ribosomal subunits
CAL13_RS07310	COG2251	uridine kinase activity
CAL13_RS07310	COG0195	Participates in both transcription termination and antitermination
CAL13_RS07315	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CAL13_RS07320	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CAL13_RS07325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CAL13_RS07330	COG1217	gtp-binding protein TYPA
CAL13_RS07345	COG0830	nickel cation binding
CAL13_RS07350	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CAL13_RS07360	COG0832	Belongs to the urease beta subunit family
CAL13_RS07370	COG0831	urea catabolic process
CAL13_RS07385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAL13_RS07385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CAL13_RS07390	COG4221	oxidoreductase activity
CAL13_RS07400	COG1283	sodium-dependent phosphate transmembrane transporter activity
CAL13_RS07405	COG1760	l-serine dehydratase
CAL13_RS07410	COG0501	Belongs to the peptidase M48B family
CAL13_RS07435	COG1722	exodeoxyribonuclease VII activity
CAL13_RS07440	COG0142	geranyltranstransferase activity
CAL13_RS07450	COG1469	GTP cyclohydrolase I activity
CAL13_RS07455	COG0360	Binds together with S18 to 16S ribosomal RNA
CAL13_RS07460	COG2965	DNA replication, synthesis of RNA primer
CAL13_RS07465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CAL13_RS07470	COG0359	binds to the 23S rRNA
CAL13_RS07480	COG0305	Participates in initiation and elongation during chromosome replication
CAL13_RS07490	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CAL13_RS07495	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CAL13_RS07500	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CAL13_RS07505	COG3737	Protein of unknown function (DUF498/DUF598)
CAL13_RS07510	COG0436	Aminotransferase
CAL13_RS07525	COG1131	(ABC) transporter
CAL13_RS07530	COG0842	Transport permease protein
CAL13_RS07535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CAL13_RS07550	COG1562	ergosterol biosynthetic process
CAL13_RS07555	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CAL13_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS07575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAL13_RS07590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CAL13_RS07605	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CAL13_RS07610	COG3842	ATPase activity
CAL13_RS07615	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL13_RS07620	COG1177	transmembrane transport
CAL13_RS07625	COG1393	Belongs to the ArsC family
CAL13_RS07645	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CAL13_RS07650	COG0704	Plays a role in the regulation of phosphate uptake
CAL13_RS07655	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CAL13_RS07660	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CAL13_RS07660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL13_RS07670	COG1643	Atp-dependent helicase
CAL13_RS07685	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS07690	COG0726	polysaccharide deacetylase
CAL13_RS07695	COG0463	Glycosyl transferase, family 2
CAL13_RS07700	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS07740	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL13_RS07790	COG1132	(ABC) transporter
CAL13_RS07830	COG1301	dicarboxylic acid transport
CAL13_RS07840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS07845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS07875	COG0596	Alpha beta hydrolase
CAL13_RS07880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CAL13_RS07890	COG1802	Transcriptional regulator
CAL13_RS07895	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CAL13_RS07905	COG0156	8-amino-7-oxononanoate synthase activity
CAL13_RS07920	COG0424	maF-like protein
CAL13_RS07925	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CAL13_RS07930	COG0799	negative regulation of ribosome biogenesis
CAL13_RS07935	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CAL13_RS07945	COG0151	Belongs to the GarS family
CAL13_RS07950	COG0217	transcriptional regulatory protein
CAL13_RS07955	COG0433	COG0433 Predicted ATPase
CAL13_RS07960	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CAL13_RS07965	COG0473	3-isopropylmalate dehydrogenase activity
CAL13_RS07975	COG2814	Major facilitator Superfamily
CAL13_RS07980	COG1566	PFAM secretion protein HlyD family protein
CAL13_RS07990	COG1846	Transcriptional regulator
CAL13_RS08010	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CAL13_RS08015	COG0308	aminopeptidase N
CAL13_RS08035	COG0312	modulator of DNA gyrase
CAL13_RS08040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CAL13_RS08045	COG0277	FAD linked oxidase domain protein
CAL13_RS08050	COG0277	FAD linked oxidase domain protein
CAL13_RS08055	COG0277	FAD linked oxidase domain protein
CAL13_RS08060	COG0247	lactate metabolic process
CAL13_RS08080	COG0482	sulfurtransferase activity
CAL13_RS08085	COG0730	response to heat
CAL13_RS08090	COG0625	glutathione transferase activity
CAL13_RS08115	COG1278	Cold shock
CAL13_RS08140	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAL13_RS08145	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CAL13_RS08165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL13_RS08180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CAL13_RS08190	COG2204	response regulator
CAL13_RS08195	COG2204	response regulator
CAL13_RS08200	COG0693	protein deglycase activity
CAL13_RS08215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CAL13_RS08235	COG3048	D-serine ammonia-lyase activity
CAL13_RS08245	COG0557	exoribonuclease II activity
CAL13_RS08250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL13_RS08255	COG2873	o-acetylhomoserine
CAL13_RS08260	COG3128	pkhd-type hydroxylase
CAL13_RS08265	COG0776	regulation of translation
CAL13_RS08280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL13_RS08290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS08295	COG2301	Belongs to the HpcH HpaI aldolase family
CAL13_RS08300	COG0583	DNA-binding transcription factor activity
CAL13_RS08325	COG0642	Histidine kinase
CAL13_RS08330	COG3158	transport of potassium into the cell
CAL13_RS08340	COG2814	Major facilitator Superfamily
CAL13_RS08345	COG0154	amidase activity
CAL13_RS08350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CAL13_RS08360	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL13_RS08375	COG2186	Transcriptional regulator
CAL13_RS08385	COG3836	Belongs to the HpcH HpaI aldolase family
CAL13_RS08390	COG0268	Binds directly to 16S ribosomal RNA
CAL13_RS08400	COG0728	peptidoglycan biosynthetic process
CAL13_RS08410	COG0563	adenylate kinase activity
CAL13_RS08415	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CAL13_RS08420	COG2835	tetraacyldisaccharide 4'-kinase activity
CAL13_RS08430	COG0848	biopolymer transport protein
CAL13_RS08435	COG0811	peptide transport
CAL13_RS08445	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL13_RS08455	COG0183	Belongs to the thiolase family
CAL13_RS08465	COG1278	Cold shock
CAL13_RS08470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CAL13_RS08475	COG0542	response to heat
CAL13_RS08480	COG2995	paraquat-inducible protein a
CAL13_RS08485	COG3008	intermembrane lipid transfer
CAL13_RS08485	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CAL13_RS08495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL13_RS08495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CAL13_RS08495	COG0506	proline dehydrogenase activity
CAL13_RS08515	COG0411	ABC transporter
CAL13_RS08525	COG1914	H( )-stimulated, divalent metal cation uptake system
CAL13_RS08530	COG1764	response to oxidative stress
CAL13_RS08545	COG1902	pentaerythritol trinitrate reductase activity
CAL13_RS08550	COG0756	dUTP diphosphatase activity
CAL13_RS08565	COG1988	membrane-bound metal-dependent
CAL13_RS08570	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CAL13_RS08575	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CAL13_RS08580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CAL13_RS08585	COG0196	riboflavin kinase activity
CAL13_RS08590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CAL13_RS08595	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CAL13_RS08595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL13_RS08610	COG0210	DNA helicase
CAL13_RS08615	COG0488	(ABC) transporter
CAL13_RS08620	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL13_RS08630	COG2171	N-acyltransferase activity
CAL13_RS08635	COG0436	Aminotransferase
CAL13_RS08645	COG0582	viral genome integration into host DNA
CAL13_RS08815	COG1802	Transcriptional regulator
CAL13_RS08815	COG4626	Terminase
CAL13_RS08825	COG0740	serine-type endopeptidase activity
CAL13_RS08945	COG1278	Cold shock
CAL13_RS08955	COG0544	peptidyl-prolyl cis-trans isomerase activity
CAL13_RS08960	COG0740	serine-type endopeptidase activity
CAL13_RS08965	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CAL13_RS08970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAL13_RS08975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CAL13_RS08985	COG0556	nucleotide-excision repair
CAL13_RS08990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CAL13_RS09000	COG1104	cysteine desulfurase activity
CAL13_RS09005	COG0822	iron-sulfur transferase activity
CAL13_RS09010	COG0316	Belongs to the HesB IscA family
CAL13_RS09020	COG0443	Heat shock 70 kDa protein
CAL13_RS09025	COG0633	Ferredoxin
CAL13_RS09035	COG1803	Methylglyoxal synthase
CAL13_RS09040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CAL13_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS09055	COG2271	Major facilitator Superfamily
CAL13_RS09075	COG1136	(ABC) transporter
CAL13_RS09080	COG0084	hydrolase, TatD family'
CAL13_RS09100	COG0613	PHP domain protein
CAL13_RS09110	COG0047	phosphoribosylformylglycinamidine synthase activity
CAL13_RS09110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CAL13_RS09130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL13_RS09140	COG0519	Catalyzes the synthesis of GMP from XMP
CAL13_RS09140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL13_RS09145	COG0582	viral genome integration into host DNA
CAL13_RS09215	COG1002	Type II restriction enzyme, methylase subunits
CAL13_RS09220	COG1061	Type III restriction enzyme res subunit
CAL13_RS09225	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CAL13_RS09275	COG0583	DNA-binding transcription factor activity
CAL13_RS09295	COG0789	Transcriptional regulator
CAL13_RS09325	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL13_RS09335	COG2814	Major facilitator Superfamily
CAL13_RS09340	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAL13_RS09385	COG0659	secondary active sulfate transmembrane transporter activity
CAL13_RS09390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL13_RS09395	COG1522	sequence-specific DNA binding
CAL13_RS09400	COG0583	DNA-binding transcription factor activity
CAL13_RS09410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CAL13_RS09415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL13_RS09420	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CAL13_RS09425	COG0583	DNA-binding transcription factor activity
CAL13_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS09435	COG0477	Major facilitator Superfamily
CAL13_RS09455	COG0477	Major facilitator Superfamily
CAL13_RS09470	COG3842	ATPase activity
CAL13_RS09480	COG0395	ABC-type sugar transport system, permease component
CAL13_RS09495	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS09500	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS09505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CAL13_RS09510	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL13_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS09545	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS09550	COG0824	Thioesterase
CAL13_RS09550	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL13_RS09555	COG3246	L-lysine catabolic process to acetate
CAL13_RS09565	COG1802	Transcriptional regulator
CAL13_RS09570	COG3959	Transketolase, thiamine diphosphate binding domain
CAL13_RS09575	COG3958	Transketolase
CAL13_RS09580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL13_RS09595	COG1136	(ABC) transporter
CAL13_RS09600	COG0577	efflux transmembrane transporter activity
CAL13_RS09620	COG1566	PFAM secretion protein HlyD family protein
CAL13_RS09630	COG1289	transmembrane transporter activity
CAL13_RS09650	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL13_RS09660	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CAL13_RS09670	COG0366	Alpha amylase catalytic
CAL13_RS09675	COG0297	glycogen (starch) synthase activity
CAL13_RS09680	COG1793	dna ligase
CAL13_RS09680	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CAL13_RS09685	COG1793	dna ligase
CAL13_RS09710	COG0726	polysaccharide deacetylase
CAL13_RS09715	COG2814	Major facilitator Superfamily
CAL13_RS09720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL13_RS09730	COG3655	Transcriptional regulator
CAL13_RS09735	COG0720	synthase
CAL13_RS09740	COG0602	queuosine metabolic process
CAL13_RS09745	COG2252	PERMEase
CAL13_RS09750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CAL13_RS09755	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CAL13_RS09760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CAL13_RS09765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL13_RS09790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CAL13_RS09795	COG0165	Argininosuccinate lyase
CAL13_RS09810	COG2154	pterin-4-alpha-carbinolamine dehydratase
CAL13_RS09825	COG0747	negative chemotaxis
CAL13_RS09830	COG0601	transmembrane transport
CAL13_RS09835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS09840	COG4172	Belongs to the ABC transporter superfamily
CAL13_RS09850	COG4681	YaeQ
CAL13_RS09855	COG3161	chorismate lyase activity
CAL13_RS09860	COG1187	pseudouridine synthase activity
CAL13_RS09875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CAL13_RS09890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CAL13_RS09895	COG0584	glycerophosphoryl diester phosphodiesterase
CAL13_RS09900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL13_RS09910	COG4181	ATPase activity
CAL13_RS09935	COG4336	lyase activity
CAL13_RS09965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CAL13_RS09990	COG1522	sequence-specific DNA binding
CAL13_RS10000	COG0386	Belongs to the glutathione peroxidase family
CAL13_RS10010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS10015	COG1393	Belongs to the ArsC family
CAL13_RS10030	COG2259	Doxx family
CAL13_RS10035	COG0010	Belongs to the arginase family
CAL13_RS10050	COG3842	ATPase activity
CAL13_RS10055	COG0395	ABC-type sugar transport system, permease component
CAL13_RS10060	COG1175	transmembrane transport
CAL13_RS10065	COG1653	transport
CAL13_RS10080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CAL13_RS10085	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CAL13_RS10095	COG0084	hydrolase, TatD family'
CAL13_RS10105	COG1742	UPF0060 membrane protein
CAL13_RS10120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS10125	COG0765	amino acid transport
CAL13_RS10130	COG1126	abc transporter atp-binding protein
CAL13_RS10135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL13_RS10140	COG1758	RNA polymerase activity
CAL13_RS10145	COG0194	GDP metabolic process
CAL13_RS10150	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS10155	COG0791	NLP P60 protein
CAL13_RS10160	COG4206	TonB-dependent receptor
CAL13_RS10175	COG3781	membrane
CAL13_RS10180	COG2304	oxidoreductase activity
CAL13_RS10185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL13_RS10190	COG0714	Associated with various cellular activities
CAL13_RS10200	COG2304	oxidoreductase activity
CAL13_RS10205	COG1561	YicC-like family, N-terminal region
CAL13_RS10210	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CAL13_RS10215	COG0840	transmembrane signaling receptor activity
CAL13_RS10225	COG3468	outer membrane autotransporter barrel domain protein
CAL13_RS10230	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CAL13_RS10235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CAL13_RS10240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CAL13_RS10245	COG0174	glutamine synthetase
CAL13_RS10260	COG0583	DNA-binding transcription factor activity
CAL13_RS10265	COG1741	Belongs to the pirin family
CAL13_RS10270	COG1741	Belongs to the pirin family
CAL13_RS10275	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS10280	COG2084	Dehydrogenase
CAL13_RS10285	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS10290	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS10295	COG0583	DNA-binding transcription factor activity
CAL13_RS10315	COG0411	ABC transporter
CAL13_RS10325	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS10350	COG0583	DNA-binding transcription factor activity
CAL13_RS10355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CAL13_RS10360	COG3842	ATPase activity
CAL13_RS10365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CAL13_RS10370	COG1840	ABC-type Fe3 transport system, periplasmic component
CAL13_RS10380	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS10405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CAL13_RS10410	COG0583	DNA-binding transcription factor activity
CAL13_RS10420	COG0783	Belongs to the Dps family
CAL13_RS10435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CAL13_RS10450	COG1454	alcohol dehydrogenase
CAL13_RS10460	COG2070	2-Nitropropane dioxygenase
CAL13_RS10475	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS10480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS10485	COG0179	Fumarylacetoacetate (FAA) hydrolase
CAL13_RS10490	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS10500	COG1802	Transcriptional regulator
CAL13_RS10505	COG4948	Mandelate Racemase Muconate Lactonizing
CAL13_RS10530	COG2188	Transcriptional regulator
CAL13_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS10560	COG2197	response regulator
CAL13_RS10565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CAL13_RS10590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS10600	COG1902	pentaerythritol trinitrate reductase activity
CAL13_RS10615	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL13_RS10640	COG0747	negative chemotaxis
CAL13_RS10645	COG4608	Belongs to the ABC transporter superfamily
CAL13_RS10660	COG0601	transmembrane transport
CAL13_RS10665	COG2072	flavoprotein involved in K transport
CAL13_RS10685	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
CAL13_RS10695	COG0656	L-ascorbic acid biosynthetic process
CAL13_RS10700	COG0840	transmembrane signaling receptor activity
CAL13_RS10710	COG1477	protein flavinylation
CAL13_RS10735	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS10770	COG0583	DNA-binding transcription factor activity
CAL13_RS10795	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CAL13_RS10800	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CAL13_RS10810	COG0596	Alpha beta hydrolase
CAL13_RS10895	COG0431	NADPH-dependent FMN reductase
CAL13_RS10910	COG0640	Transcriptional regulator
CAL13_RS10930	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CAL13_RS10935	COG1024	Enoyl-CoA hydratase
CAL13_RS10945	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS10955	COG0183	Belongs to the thiolase family
CAL13_RS10975	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS10990	COG2030	dehydratase
CAL13_RS11000	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS11020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CAL13_RS11035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CAL13_RS11040	COG1671	Belongs to the UPF0178 family
CAL13_RS11055	COG0583	DNA-binding transcription factor activity
CAL13_RS11060	COG1380	Effector of murein hydrolase LrgA
CAL13_RS11065	COG1346	cytolysis
CAL13_RS11075	COG2201	protein-glutamate methylesterase activity
CAL13_RS11120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS11140	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS11155	COG1414	Transcriptional regulator
CAL13_RS11160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL13_RS11165	COG0477	Major facilitator Superfamily
CAL13_RS11170	COG2376	Dihydroxyacetone kinase
CAL13_RS11180	COG0583	DNA-binding transcription factor activity
CAL13_RS11200	COG3008	intermembrane lipid transfer
CAL13_RS11225	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS11235	COG0583	DNA-binding transcription factor activity
CAL13_RS11260	COG0784	Response regulator, receiver
CAL13_RS11260	COG4191	Histidine kinase
CAL13_RS11265	COG4946	Tricorn protease homolog
CAL13_RS11265	COG1506	peptidase
CAL13_RS11265	COG0823	Involved in the tonB-independent uptake of proteins
CAL13_RS11345	COG1090	epimerase
CAL13_RS11370	COG1132	(ABC) transporter
CAL13_RS11390	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS11405	COG2159	amidohydrolase
CAL13_RS11410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL13_RS11430	COG0583	DNA-binding transcription factor activity
CAL13_RS11445	COG4251	negative regulation of phosphorylation
CAL13_RS11450	COG0784	Response regulator, receiver
CAL13_RS11465	COG1942	4-Oxalocrotonate Tautomerase
CAL13_RS11490	COG1309	transcriptional regulator
CAL13_RS11520	COG0165	Argininosuccinate lyase
CAL13_RS11525	COG0697	spore germination
CAL13_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS11550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS11580	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL13_RS11600	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CAL13_RS11605	COG1335	isochorismatase
CAL13_RS11610	COG2309	aminopeptidase activity
CAL13_RS11615	COG0596	Alpha beta hydrolase
CAL13_RS11620	COG3473	Maleate cis-trans isomerase
CAL13_RS11645	COG2423	ornithine cyclodeaminase activity
CAL13_RS11660	COG2267	carboxylic ester hydrolase activity
CAL13_RS11665	COG1228	amidohydrolase
CAL13_RS11670	COG1879	ABC-type sugar transport system periplasmic component
CAL13_RS11680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS11690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL13_RS11690	COG2010	Cytochrome c
CAL13_RS11705	COG2010	Cytochrome c
CAL13_RS11720	COG1053	succinate dehydrogenase
CAL13_RS11720	COG3976	FMN-binding domain protein
CAL13_RS11730	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS11740	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS11750	COG1609	Transcriptional regulator
CAL13_RS11770	COG0432	Pfam Uncharacterised protein family UPF0047
CAL13_RS11790	COG0405	Gamma-glutamyltransferase
CAL13_RS11795	COG0583	DNA-binding transcription factor activity
CAL13_RS11840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CAL13_RS11840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CAL13_RS11850	COG3550	peptidyl-serine autophosphorylation
CAL13_RS11880	COG0642	Histidine kinase
CAL13_RS11885	COG1304	FMN binding
CAL13_RS11900	COG1538	Outer membrane efflux protein
CAL13_RS11905	COG0473	3-isopropylmalate dehydrogenase activity
CAL13_RS11910	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS11930	COG0596	Alpha beta hydrolase
CAL13_RS11935	COG1228	amidohydrolase
CAL13_RS11960	COG5441	Belongs to the UPF0261 family
CAL13_RS11965	COG5564	TIM-barrel signal transduction protein
CAL13_RS11970	COG2268	Band 7 protein
CAL13_RS11980	COG0583	DNA-binding transcription factor activity
CAL13_RS12005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS12005	COG2205	protein histidine kinase activity
CAL13_RS12030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CAL13_RS12040	COG0583	DNA-binding transcription factor activity
CAL13_RS12045	COG0735	belongs to the Fur family
CAL13_RS12050	COG0628	permease
CAL13_RS12055	COG1464	Belongs to the NlpA lipoprotein family
CAL13_RS12060	COG0288	reversible hydration of carbon dioxide
CAL13_RS12070	COG4974	Belongs to the 'phage' integrase family
CAL13_RS12085	COG1116	anion transmembrane transporter activity
CAL13_RS12090	COG0395	ABC-type sugar transport system, permease component
CAL13_RS12100	COG2363	Small membrane protein
CAL13_RS12110	COG2814	Major facilitator Superfamily
CAL13_RS12125	COG0390	transport system, permease component
CAL13_RS12145	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL13_RS12165	COG0411	ABC transporter
CAL13_RS12175	COG0559	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS12195	COG1024	Enoyl-CoA hydratase
CAL13_RS12200	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS12205	COG2914	Belongs to the UPF0125 (RnfH) family
CAL13_RS12215	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CAL13_RS12225	COG0330	HflC and HflK could
CAL13_RS12235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CAL13_RS12235	COG0519	Catalyzes the synthesis of GMP from XMP
CAL13_RS12240	COG2169	Transcriptional regulator
CAL13_RS12240	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CAL13_RS12255	COG0640	Transcriptional regulator
CAL13_RS12260	COG2249	NAD(P)H dehydrogenase (quinone) activity
CAL13_RS12265	COG2814	Major facilitator Superfamily
CAL13_RS12270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CAL13_RS12275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CAL13_RS12280	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL13_RS12290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CAL13_RS12295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL13_RS12300	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CAL13_RS12310	COG0750	zinc metalloprotease
CAL13_RS12315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CAL13_RS12320	COG0575	Belongs to the CDS family
CAL13_RS12325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CAL13_RS12330	COG0233	cytoplasmic translational termination
CAL13_RS12335	COG0528	UMP kinase activity
CAL13_RS12340	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CAL13_RS12345	COG0052	Belongs to the universal ribosomal protein uS2 family
CAL13_RS12350	COG0024	Methionine aminopeptidase
CAL13_RS12355	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CAL13_RS12385	COG0285	dihydrofolate synthase activity
CAL13_RS12390	COG1334	flagellar protein FlaG
CAL13_RS12395	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CAL13_RS12415	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAL13_RS12425	COG5001	Diguanylate cyclase
CAL13_RS12425	COG3300	MHYT domain
CAL13_RS12430	COG1677	Flagellar hook-basal body complex protein FliE
CAL13_RS12440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL13_RS12465	COG1580	Controls the rotational direction of flagella during chemotaxis
CAL13_RS12470	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL13_RS12475	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CAL13_RS12510	COG0840	transmembrane signaling receptor activity
CAL13_RS12525	COG0840	transmembrane signaling receptor activity
CAL13_RS12530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CAL13_RS12535	COG1256	bacterial-type flagellum assembly
CAL13_RS12540	COG3951	Flagellar rod assembly protein muramidase FlgJ
CAL13_RS12540	COG1705	Flagellar rod assembly protein muramidase FlgJ
CAL13_RS12560	COG4787	bacterial-type flagellum-dependent cell motility
CAL13_RS12575	COG1558	bacterial-type flagellum-dependent cell motility
CAL13_RS12585	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CAL13_RS12610	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CAL13_RS12615	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CAL13_RS12620	COG0745	RESPONSE REGULATOR receiver
CAL13_RS12625	COG2201	protein-glutamate methylesterase activity
CAL13_RS12630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CAL13_RS12635	COG0840	transmembrane signaling receptor activity
CAL13_RS12640	COG0835	chemotaxis
CAL13_RS12650	COG0745	RESPONSE REGULATOR receiver
CAL13_RS12675	COG1191	sigma factor activity
CAL13_RS12700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL13_RS12700	COG4797	methyltransferase
CAL13_RS12705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CAL13_RS12710	COG0508	dehydrogenase complex catalyzes the overall conversion of
CAL13_RS12725	COG4566	intracellular signal transduction
CAL13_RS12730	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CAL13_RS12735	COG0339	signal peptide processing
CAL13_RS12740	COG1999	signal sequence binding
CAL13_RS12755	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CAL13_RS12755	COG0678	peroxiredoxin activity
CAL13_RS12770	COG0789	Transcriptional regulator
CAL13_RS12780	COG0789	Transcriptional regulator
CAL13_RS12820	COG2197	response regulator
CAL13_RS12830	COG2274	protein secretion by the type I secretion system
CAL13_RS12840	COG1538	Outer membrane efflux protein
CAL13_RS12850	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CAL13_RS12860	COG3642	lipopolysaccharide core region biosynthetic process
CAL13_RS12875	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CAL13_RS12885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CAL13_RS12890	COG0667	Aldo Keto reductase
CAL13_RS12895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL13_RS12915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CAL13_RS12920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL13_RS12930	COG0488	(ABC) transporter
CAL13_RS12940	COG4651	solute:proton antiporter activity
CAL13_RS12940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CAL13_RS12945	COG1619	proteins homologs of microcin C7 resistance protein MccF
CAL13_RS12950	COG0590	tRNA wobble adenosine to inosine editing
CAL13_RS12975	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS12990	COG2951	lytic endotransglycosylase activity
CAL13_RS13015	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS13030	COG0583	DNA-binding transcription factor activity
CAL13_RS13035	COG0477	Major facilitator Superfamily
CAL13_RS13045	COG0656	L-ascorbic acid biosynthetic process
CAL13_RS13065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS13070	COG1126	abc transporter atp-binding protein
CAL13_RS13075	COG0765	amino acid transport
CAL13_RS13080	COG0765	amino acid transport
CAL13_RS13100	COG0583	DNA-binding transcription factor activity
CAL13_RS13105	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS13110	COG1201	RNA secondary structure unwinding
CAL13_RS13135	COG3237	CsbD-like
CAL13_RS13140	COG4774	siderophore transport
CAL13_RS13145	COG2375	cellular response to nickel ion
CAL13_RS13150	COG1695	Transcriptional regulator
CAL13_RS13165	COG0587	DNA-directed DNA polymerase activity
CAL13_RS13180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS13185	COG0583	DNA-binding transcription factor activity
CAL13_RS13200	COG0204	Acyl-transferase
CAL13_RS13205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL13_RS13210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL13_RS13270	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS13275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAL13_RS13310	COG2223	nitrite transmembrane transporter activity
CAL13_RS13315	COG2207	Transcriptional regulator
CAL13_RS13325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL13_RS13335	COG5265	(ABC) transporter
CAL13_RS13385	COG0745	RESPONSE REGULATOR receiver
CAL13_RS13390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL13_RS13410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CAL13_RS13410	COG0072	phenylalanine-tRNA ligase activity
CAL13_RS13415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CAL13_RS13420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CAL13_RS13425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CAL13_RS13445	COG0004	ammonium transporteR
CAL13_RS13450	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CAL13_RS13455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CAL13_RS13470	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CAL13_RS13475	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CAL13_RS13480	COG2197	response regulator
CAL13_RS13485	COG2205	protein histidine kinase activity
CAL13_RS13485	COG5002	protein histidine kinase activity
CAL13_RS13485	COG0784	Response regulator, receiver
CAL13_RS13495	COG2200	EAL domain
CAL13_RS13505	COG0135	phosphoribosylanthranilate isomerase activity
CAL13_RS13510	COG0101	tRNA pseudouridine synthase activity
CAL13_RS13520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CAL13_RS13545	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CAL13_RS13560	COG2205	protein histidine kinase activity
CAL13_RS13565	COG0745	RESPONSE REGULATOR receiver
CAL13_RS13570	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CAL13_RS13580	COG1295	ribonuclease BN
CAL13_RS13585	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CAL13_RS13585	COG0517	IMP dehydrogenase activity
CAL13_RS13590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CAL13_RS13680	COG0181	hydroxymethylbilane synthase activity
CAL13_RS13685	COG0861	Integral membrane protein TerC family
CAL13_RS13690	COG0861	Integral membrane protein TerC family
CAL13_RS13695	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS13705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CAL13_RS13710	COG0045	succinate-CoA ligase (ADP-forming) activity
CAL13_RS13720	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CAL13_RS13730	COG2137	regulation of response to DNA damage stimulus
CAL13_RS13735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CAL13_RS13750	COG0477	Major facilitator Superfamily
CAL13_RS13775	COG0540	Belongs to the ATCase OTCase family
CAL13_RS13825	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CAL13_RS13835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS13875	COG0477	Major facilitator Superfamily
CAL13_RS13880	COG1686	Belongs to the peptidase S11 family
CAL13_RS13890	COG1297	OPT oligopeptide transporter protein
CAL13_RS13905	COG0668	transmembrane transport
CAL13_RS13925	COG1278	Cold shock
CAL13_RS13955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CAL13_RS13965	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CAL13_RS13975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CAL13_RS13980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CAL13_RS13985	COG0330	HflC and HflK could
CAL13_RS13990	COG0330	HflC and HflK could
CAL13_RS13995	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CAL13_RS14000	COG1923	regulation of RNA biosynthetic process
CAL13_RS14010	COG1160	GTP binding
CAL13_RS14015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL13_RS14040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CAL13_RS14045	COG0105	UTP biosynthetic process
CAL13_RS14050	COG0525	valine-tRNA ligase activity
CAL13_RS14055	COG0336	Belongs to the RNA methyltransferase TrmD family
CAL13_RS14060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CAL13_RS14065	COG0228	four-way junction DNA binding
CAL13_RS14070	COG0425	Belongs to the sulfur carrier protein TusA family
CAL13_RS14075	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CAL13_RS14125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS14135	COG2076	Multidrug Resistance protein
CAL13_RS14140	COG0633	Ferredoxin
CAL13_RS14140	COG3217	Mosc domain protein beta barrel domain protein
CAL13_RS14145	COG5285	phytanoyl-CoA dioxygenase
CAL13_RS14150	COG0662	Cupin 2, conserved barrel domain protein
CAL13_RS14160	COG0456	acetyltransferase
CAL13_RS14180	COG3118	belongs to the thioredoxin family
CAL13_RS14185	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CAL13_RS14195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CAL13_RS14200	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CAL13_RS14205	COG0028	Belongs to the TPP enzyme family
CAL13_RS14210	COG0542	response to heat
CAL13_RS14215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CAL13_RS14255	COG1174	glycine betaine transport
CAL13_RS14280	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CAL13_RS14295	COG0642	Histidine kinase
CAL13_RS14300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL13_RS14305	COG4942	peptidase
CAL13_RS14325	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CAL13_RS14330	COG0842	Transport permease protein
CAL13_RS14335	COG1131	(ABC) transporter
CAL13_RS14340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL13_RS14340	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CAL13_RS14345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CAL13_RS14360	COG0736	holo-[acyl-carrier-protein] synthase activity
CAL13_RS14365	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CAL13_RS14370	COG0745	RESPONSE REGULATOR receiver
CAL13_RS14385	COG4120	Belongs to the binding-protein-dependent transport system permease family
CAL13_RS14405	COG0318	PFAM AMP-dependent synthetase and ligase
CAL13_RS14410	COG1024	Enoyl-CoA hydratase
CAL13_RS14420	COG1802	Transcriptional regulator
CAL13_RS14430	COG0183	Belongs to the thiolase family
CAL13_RS14440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CAL13_RS14445	COG2814	Major facilitator Superfamily
CAL13_RS14450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CAL13_RS14455	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CAL13_RS14470	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS14480	COG1802	Transcriptional regulator
CAL13_RS14495	COG2814	Major facilitator Superfamily
CAL13_RS14500	COG0495	leucyl-tRNA aminoacylation
CAL13_RS14515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CAL13_RS14520	COG1981	membrane
CAL13_RS14530	COG1984	allophanate hydrolase subunit 2
CAL13_RS14535	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAL13_RS14550	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CAL13_RS14570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL13_RS14580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CAL13_RS14595	COG0148	phosphopyruvate hydratase activity
CAL13_RS14600	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CAL13_RS14605	COG0504	CTP synthase activity
CAL13_RS14610	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS14640	COG0747	negative chemotaxis
CAL13_RS14645	COG4172	Belongs to the ABC transporter superfamily
CAL13_RS14650	COG1446	asparaginase
CAL13_RS14660	COG0392	lysyltransferase activity
CAL13_RS14665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL13_RS14670	COG3568	Endonuclease Exonuclease Phosphatase
CAL13_RS14705	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CAL13_RS14710	COG0697	spore germination
CAL13_RS14715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL13_RS14720	COG3938	Belongs to the proline racemase family
CAL13_RS14730	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CAL13_RS14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CAL13_RS14740	COG0791	NLP P60 protein
CAL13_RS14750	COG0583	DNA-binding transcription factor activity
CAL13_RS14800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CAL13_RS14830	COG1381	Involved in DNA repair and RecF pathway recombination
CAL13_RS14835	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CAL13_RS14840	COG0571	ribonuclease III activity
CAL13_RS14845	COG0681	Belongs to the peptidase S26 family
CAL13_RS14850	COG0481	GTPase activity
CAL13_RS14855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL13_RS14880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CAL13_RS14885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CAL13_RS14890	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS14900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CAL13_RS14910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CAL13_RS14920	COG0424	maF-like protein
CAL13_RS14930	COG3023	N-Acetylmuramoyl-L-alanine amidase
CAL13_RS14935	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CAL13_RS14940	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CAL13_RS14950	COG0564	pseudouridine synthase activity
CAL13_RS14955	COG1530	ribonuclease E activity
CAL13_RS14960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CAL13_RS14965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CAL13_RS14970	COG0159	tryptophan synthase activity
CAL13_RS14980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL13_RS14985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CAL13_RS14990	COG3228	Belongs to the MtfA family
CAL13_RS14995	COG0251	oxidation-reduction process
CAL13_RS15005	COG0010	Belongs to the arginase family
CAL13_RS15015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CAL13_RS15025	COG0765	amino acid transport
CAL13_RS15030	COG0765	amino acid transport
CAL13_RS15035	COG4598	ABC transporter
CAL13_RS15040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CAL13_RS15050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CAL13_RS15055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CAL13_RS15065	COG2878	Part of a membrane complex involved in electron transport
CAL13_RS15070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CAL13_RS15110	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CAL13_RS15115	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS15130	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CAL13_RS15145	COG4172	Belongs to the ABC transporter superfamily
CAL13_RS15150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS15155	COG0601	transmembrane transport
CAL13_RS15170	COG0598	Magnesium transport protein CorA
CAL13_RS15185	COG0210	DNA helicase
CAL13_RS15215	COG0483	inositol monophosphate 1-phosphatase activity
CAL13_RS15220	COG1045	serine acetyltransferase
CAL13_RS15225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CAL13_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS15250	COG0183	Belongs to the thiolase family
CAL13_RS15260	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL13_RS15265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS15275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CAL13_RS15280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CAL13_RS15285	COG3206	protein involved in exopolysaccharide biosynthesis
CAL13_RS15285	COG0489	protein tyrosine kinase activity
CAL13_RS15295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CAL13_RS15300	COG1051	belongs to the nudix hydrolase family
CAL13_RS15305	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CAL13_RS15305	COG0662	Cupin 2, conserved barrel domain protein
CAL13_RS15310	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CAL13_RS15315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CAL13_RS15335	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS15345	COG0110	maltose O-acetyltransferase activity
CAL13_RS15350	COG0297	glycogen (starch) synthase activity
CAL13_RS15355	COG2197	response regulator
CAL13_RS15370	COG2205	protein histidine kinase activity
CAL13_RS15375	COG0745	RESPONSE REGULATOR receiver
CAL13_RS15380	COG2814	Major facilitator Superfamily
CAL13_RS15385	COG4221	oxidoreductase activity
CAL13_RS15410	COG0583	DNA-binding transcription factor activity
CAL13_RS15425	COG1053	succinate dehydrogenase
CAL13_RS15440	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS15470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CAL13_RS15495	COG0037	tRNA processing
CAL13_RS15500	COG0825	malonyl-CoA metabolic process
CAL13_RS15510	COG0215	cysteine-tRNA ligase activity
CAL13_RS15520	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CAL13_RS15525	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CAL13_RS15530	COG1968	undecaprenyl-diphosphatase activity
CAL13_RS15535	COG1253	flavin adenine dinucleotide binding
CAL13_RS15540	COG0483	inositol monophosphate 1-phosphatase activity
CAL13_RS15560	COG0668	transmembrane transport
CAL13_RS15575	COG3360	Dodecin
CAL13_RS15590	COG0477	Major facilitator Superfamily
CAL13_RS15595	COG0076	glutamate decarboxylase activity
CAL13_RS15610	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CAL13_RS15615	COG2850	peptidyl-arginine hydroxylation
CAL13_RS15625	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CAL13_RS15630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL13_RS15635	COG1994	Peptidase M50
CAL13_RS15640	COG0009	L-threonylcarbamoyladenylate synthase
CAL13_RS15645	COG2321	neutral zinc metallopeptidase
CAL13_RS15650	COG0494	nUDIX hydrolase
CAL13_RS15700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CAL13_RS15705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL13_RS15710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS15715	COG1116	anion transmembrane transporter activity
CAL13_RS15720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL13_RS15725	COG0243	molybdopterin cofactor binding
CAL13_RS15740	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL13_RS15750	COG0387	Pfam Sodium calcium exchanger
CAL13_RS15770	COG0437	4 iron, 4 sulfur cluster binding
CAL13_RS15805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CAL13_RS15815	COG1845	cytochrome c oxidase, subunit III
CAL13_RS15850	COG3546	catalase activity
CAL13_RS15855	COG3685	Protein conserved in bacteria
CAL13_RS15860	COG3685	Protein conserved in bacteria
CAL13_RS15865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS15885	COG1177	transmembrane transport
CAL13_RS15890	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL13_RS15895	COG3842	ATPase activity
CAL13_RS15920	COG0477	Major facilitator Superfamily
CAL13_RS15925	COG0477	Major facilitator Superfamily
CAL13_RS15935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CAL13_RS15955	COG1137	ATPase activity
CAL13_RS15975	COG1802	Transcriptional regulator
CAL13_RS15990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL13_RS16000	COG0583	DNA-binding transcription factor activity
CAL13_RS16005	COG0385	Bile acid
CAL13_RS16010	COG0596	Alpha beta hydrolase
CAL13_RS16015	COG0456	acetyltransferase
CAL13_RS16020	COG1609	Transcriptional regulator
CAL13_RS16030	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS16035	COG1175	transmembrane transport
CAL13_RS16045	COG1063	alcohol dehydrogenase
CAL13_RS16050	COG3842	ATPase activity
CAL13_RS16055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAL13_RS16060	COG3684	Belongs to the aldolase LacD family
CAL13_RS16065	COG2146	nitrite reductase [NAD(P)H] activity
CAL13_RS16065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL13_RS16070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CAL13_RS16070	COG2146	nitrite reductase [NAD(P)H] activity
CAL13_RS16075	COG3707	response regulator
CAL13_RS16080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL13_RS16100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CAL13_RS16120	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CAL13_RS16145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CAL13_RS16160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CAL13_RS16165	COG2233	PERMEase
CAL13_RS16170	COG0406	alpha-ribazole phosphatase activity
CAL13_RS16175	COG0300	oxidoreductase activity
CAL13_RS16185	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CAL13_RS16190	COG0505	Belongs to the CarA family
CAL13_RS16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS16210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CAL13_RS16215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS16220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CAL13_RS16230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CAL13_RS16250	COG2135	peptidase activity
CAL13_RS16260	COG4695	Portal protein
CAL13_RS16280	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS16290	COG1686	Belongs to the peptidase S11 family
CAL13_RS16300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CAL13_RS16305	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS16315	COG0114	fumarate hydratase activity
CAL13_RS16325	COG0860	N-Acetylmuramoyl-L-alanine amidase
CAL13_RS16330	COG0586	Pfam SNARE associated Golgi protein
CAL13_RS16335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CAL13_RS16340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CAL13_RS16345	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CAL13_RS16360	COG0617	tRNA 3'-terminal CCA addition
CAL13_RS16375	COG1024	Enoyl-CoA hydratase
CAL13_RS16380	COG0752	glycyl-tRNA synthetase alpha subunit
CAL13_RS16385	COG0751	glycine-tRNA ligase activity
CAL13_RS16390	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CAL13_RS16395	COG0204	Acyl-transferase
CAL13_RS16415	COG0242	peptide deformylase activity
CAL13_RS16420	COG0700	Nucleoside recognition
CAL13_RS16425	COG0469	pyruvate kinase activity
CAL13_RS16430	COG1929	Belongs to the glycerate kinase type-1 family
CAL13_RS16435	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CAL13_RS16440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CAL13_RS16465	COG3038	cytochrome b561
CAL13_RS16470	COG0484	heat shock protein binding
CAL13_RS16475	COG0443	Heat shock 70 kDa protein
CAL13_RS16485	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CAL13_RS16490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CAL13_RS16495	COG1420	regulation of RNA biosynthetic process
CAL13_RS16505	COG0497	DNA recombination
CAL13_RS16510	COG0735	belongs to the Fur family
CAL13_RS16515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CAL13_RS16525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CAL13_RS16545	COG5265	(ABC) transporter
CAL13_RS16595	COG0387	Pfam Sodium calcium exchanger
CAL13_RS16625	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CAL13_RS16630	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CAL13_RS16635	COG0167	dihydroorotate dehydrogenase activity
CAL13_RS16655	COG1414	Transcriptional regulator
CAL13_RS16660	COG1546	Belongs to the CinA family
CAL13_RS16660	COG1058	Belongs to the CinA family
CAL13_RS16675	COG0513	Belongs to the DEAD box helicase family
CAL13_RS16725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CAL13_RS16740	COG0006	proline dipeptidase activity
CAL13_RS16750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL13_RS16775	COG0632	four-way junction helicase activity
CAL13_RS16780	COG1090	epimerase
CAL13_RS16790	COG2255	four-way junction helicase activity
CAL13_RS16795	COG0514	ATP-dependent DNA helicase (RecQ)
CAL13_RS16825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL13_RS16840	COG0850	regulation of cytokinetic process
CAL13_RS16845	COG2894	cell division
CAL13_RS16850	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CAL13_RS16860	COG0488	(ABC) transporter
CAL13_RS16885	COG0583	DNA-binding transcription factor activity
CAL13_RS16900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CAL13_RS16915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CAL13_RS16920	COG0745	RESPONSE REGULATOR receiver
CAL13_RS16925	COG2205	protein histidine kinase activity
CAL13_RS16940	COG0259	pyridoxamine-phosphate oxidase activity
CAL13_RS16950	COG0579	oxidoreductase
CAL13_RS16960	COG1126	abc transporter atp-binding protein
CAL13_RS16965	COG0765	amino acid transport
CAL13_RS16970	COG0765	amino acid transport
CAL13_RS16985	COG0028	Belongs to the TPP enzyme family
CAL13_RS16990	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS17000	COG2030	dehydratase
CAL13_RS17005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS17010	COG0009	L-threonylcarbamoyladenylate synthase
CAL13_RS17015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CAL13_RS17020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CAL13_RS17025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CAL13_RS17035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CAL13_RS17065	COG2199	diguanylate cyclase activity
CAL13_RS17080	COG3454	Phosphonate metabolism
CAL13_RS17085	COG4778	phosphonate C-P lyase system protein PhnL
CAL13_RS17090	COG4107	phosphonate C-P lyase system protein PhnK
CAL13_RS17095	COG3627	carbon phosphorus lyase activity
CAL13_RS17100	COG3626	phosphonate metabolism
CAL13_RS17105	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
CAL13_RS17110	COG3624	Phosphonate C-P lyase system protein PhnG
CAL13_RS17115	COG2188	Transcriptional regulator
CAL13_RS17120	COG3454	Phosphonate metabolism
CAL13_RS17125	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CAL13_RS17130	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CAL13_RS17140	COG3639	organic phosphonate transmembrane transporter activity
CAL13_RS17145	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CAL13_RS17150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CAL13_RS17155	COG2755	lipolytic protein G-D-S-L family
CAL13_RS17155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CAL13_RS17165	COG3093	addiction module antidote protein HigA
CAL13_RS17180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CAL13_RS17200	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL13_RS17205	COG0484	heat shock protein binding
CAL13_RS17225	COG0625	glutathione transferase activity
CAL13_RS17230	COG0126	phosphoglycerate kinase activity
CAL13_RS17235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CAL13_RS17245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CAL13_RS17260	COG0281	malic enzyme
CAL13_RS17260	COG0280	phosphate acetyltransferase
CAL13_RS17270	COG0436	Aminotransferase
CAL13_RS17275	COG0741	lytic transglycosylase activity
CAL13_RS17280	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CAL13_RS17295	COG4575	ribosome binding
CAL13_RS17305	COG1648	precorrin-2 dehydrogenase activity
CAL13_RS17305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CAL13_RS17310	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CAL13_RS17320	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CAL13_RS17325	COG0343	queuine tRNA-ribosyltransferase activity
CAL13_RS17330	COG1862	Preprotein translocase
CAL13_RS17345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL13_RS17360	COG3665	Urea carboxylase-associated protein
CAL13_RS17375	COG0765	amino acid transport
CAL13_RS17380	COG0765	amino acid transport
CAL13_RS17385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS17410	COG0583	DNA-binding transcription factor activity
CAL13_RS17415	COG0583	DNA-binding transcription factor activity
CAL13_RS17435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CAL13_RS17445	COG3842	ATPase activity
CAL13_RS17450	COG0395	ABC-type sugar transport system, permease component
CAL13_RS17455	COG1175	transmembrane transport
CAL13_RS17465	COG1609	Transcriptional regulator
CAL13_RS17475	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS17480	COG0318	PFAM AMP-dependent synthetase and ligase
CAL13_RS17490	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS17505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL13_RS17510	COG1702	phosphate starvation-inducible protein PhoH
CAL13_RS17515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CAL13_RS17520	COG4535	Mg2 and Co2 transporter CorC
CAL13_RS17530	COG0667	Aldo Keto reductase
CAL13_RS17695	COG0678	peroxiredoxin activity
CAL13_RS17705	COG0315	cyclic pyranopterin monophosphate synthase activity
CAL13_RS17715	COG0314	molybdopterin synthase activity
CAL13_RS17720	COG0521	Mo-molybdopterin cofactor biosynthetic process
CAL13_RS17725	COG0303	'Molybdopterin
CAL13_RS17730	COG0746	molybdenum cofactor guanylyltransferase activity
CAL13_RS17735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CAL13_RS17755	COG3383	formate dehydrogenase (NAD+) activity
CAL13_RS17760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CAL13_RS17770	COG2223	nitrite transmembrane transporter activity
CAL13_RS17785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS17790	COG0697	spore germination
CAL13_RS17815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CAL13_RS17820	COG0463	Glycosyl transferase, family 2
CAL13_RS17835	COG0277	FAD linked oxidase domain protein
CAL13_RS17840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CAL13_RS17855	COG0583	DNA-binding transcription factor activity
CAL13_RS17880	COG1012	belongs to the aldehyde dehydrogenase family
CAL13_RS17900	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS17905	COG1414	Transcriptional regulator
CAL13_RS17910	COG1418	mRNA catabolic process
CAL13_RS17920	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CAL13_RS17925	COG0328	RNA-DNA hybrid ribonuclease activity
CAL13_RS17930	COG2226	methyltransferase
CAL13_RS17935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CAL13_RS17940	COG0741	lytic transglycosylase activity
CAL13_RS17940	COG1388	LysM domain
CAL13_RS17965	COG0667	Aldo Keto reductase
CAL13_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS17975	COG1309	transcriptional regulator
CAL13_RS17980	COG0640	Transcriptional regulator
CAL13_RS17990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL13_RS17995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL13_RS18000	COG2080	2 iron, 2 sulfur cluster binding
CAL13_RS18030	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL13_RS18035	COG0165	Argininosuccinate lyase
CAL13_RS18055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CAL13_RS18075	COG0402	S-adenosylhomocysteine deaminase activity
CAL13_RS18115	COG4641	Protein conserved in bacteria
CAL13_RS18115	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS18140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS18145	COG0601	transmembrane transport
CAL13_RS18160	COG2719	SpoVR family
CAL13_RS18165	COG2718	Belongs to the UPF0229 family
CAL13_RS18170	COG2766	serine protein kinase
CAL13_RS18180	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL13_RS18180	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CAL13_RS18185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CAL13_RS18190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CAL13_RS18195	COG1881	PFAM PEBP family protein
CAL13_RS18200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CAL13_RS18205	COG0739	heme binding
CAL13_RS18210	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CAL13_RS18215	COG0316	Belongs to the HesB IscA family
CAL13_RS18225	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CAL13_RS18230	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CAL13_RS18235	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CAL13_RS18290	COG0312	modulator of DNA gyrase
CAL13_RS18295	COG3028	Belongs to the UPF0307 family
CAL13_RS18310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CAL13_RS18325	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CAL13_RS18335	COG0762	integral membrane protein
CAL13_RS18345	COG1473	amidohydrolase
CAL13_RS18350	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS18360	COG3133	Outer membrane lipoprotein
CAL13_RS18365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CAL13_RS18375	COG2264	protein methyltransferase activity
CAL13_RS18380	COG0439	Biotin carboxylase
CAL13_RS18385	COG0511	ligase activity, forming carbon-carbon bonds
CAL13_RS18390	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CAL13_RS18395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CAL13_RS18400	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CAL13_RS18405	COG3150	esterase
CAL13_RS18410	COG0557	exoribonuclease II activity
CAL13_RS18435	COG3842	ATPase activity
CAL13_RS18445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CAL13_RS18450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CAL13_RS18460	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CAL13_RS18470	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CAL13_RS18475	COG1678	Uncharacterized ACR, COG1678
CAL13_RS18485	COG0351	phosphomethylpyrimidine kinase
CAL13_RS18490	COG0352	thiamine-phosphate diphosphorylase activity
CAL13_RS18495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CAL13_RS18515	COG1024	Enoyl-CoA hydratase
CAL13_RS18520	COG1028	Short-chain dehydrogenase reductase Sdr
CAL13_RS18555	COG1137	ATPase activity
CAL13_RS18575	COG0657	acetylesterase activity
CAL13_RS18580	COG1846	Transcriptional regulator
CAL13_RS18590	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CAL13_RS18625	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CAL13_RS18635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CAL13_RS18645	COG2197	response regulator
CAL13_RS18650	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CAL13_RS18655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CAL13_RS18665	COG0477	Major facilitator Superfamily
CAL13_RS18680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS18685	COG3181	Tripartite tricarboxylate transporter family receptor
CAL13_RS18690	COG1280	lysine exporter protein (LysE YggA)
CAL13_RS18720	COG0625	glutathione transferase activity
CAL13_RS18725	COG1605	Chorismate mutase
CAL13_RS18725	COG0077	Prephenate dehydratase
CAL13_RS18735	COG2081	HI0933 family
CAL13_RS18740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL13_RS18750	COG1126	abc transporter atp-binding protein
CAL13_RS18755	COG0765	amino acid transport
CAL13_RS18760	COG4597	amino acid ABC transporter
CAL13_RS18765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS18770	COG2884	Cell division ATP-binding protein ftsE
CAL13_RS18775	COG2177	Part of the ABC transporter FtsEX involved in
CAL13_RS18780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CAL13_RS18790	COG1194	a g-specific adenine glycosylase
CAL13_RS18795	COG0772	Belongs to the SEDS family
CAL13_RS18800	COG0768	penicillin binding
CAL13_RS18810	COG1792	Involved in formation and maintenance of cell shape
CAL13_RS18815	COG1077	Cell shape determining protein MreB Mrl
CAL13_RS18820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL13_RS18825	COG0154	amidase activity
CAL13_RS18830	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CAL13_RS18835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CAL13_RS18840	COG0708	Exodeoxyribonuclease III
CAL13_RS18850	COG0589	response to stress
CAL13_RS18860	COG2223	nitrite transmembrane transporter activity
CAL13_RS18865	COG2813	Specifically methylates the guanine in position
CAL13_RS18865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL13_RS18870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CAL13_RS18875	COG2771	luxR family
CAL13_RS18885	COG2918	glutathione biosynthetic process
CAL13_RS18890	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CAL13_RS18900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS18925	COG1113	amino acid transport
CAL13_RS18935	COG3245	cytochrome
CAL13_RS18950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL13_RS18950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CAL13_RS18955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CAL13_RS18985	COG4206	TonB-dependent receptor
CAL13_RS18990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CAL13_RS18995	COG2022	thiamine diphosphate biosynthetic process
CAL13_RS19000	COG0351	phosphomethylpyrimidine kinase
CAL13_RS19005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CAL13_RS19010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CAL13_RS19020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CAL13_RS19040	COG2226	methyltransferase
CAL13_RS19045	COG0745	RESPONSE REGULATOR receiver
CAL13_RS19050	COG5002	protein histidine kinase activity
CAL13_RS19055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS19070	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CAL13_RS19075	COG1984	allophanate hydrolase subunit 2
CAL13_RS19085	COG1802	Transcriptional regulator
CAL13_RS19105	COG1238	metal cluster binding
CAL13_RS19110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CAL13_RS19130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS19145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CAL13_RS19150	COG0583	DNA-binding transcription factor activity
CAL13_RS19160	COG0601	transmembrane transport
CAL13_RS19165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS19170	COG0444	Belongs to the ABC transporter superfamily
CAL13_RS19175	COG4608	Belongs to the ABC transporter superfamily
CAL13_RS19190	COG0210	DNA helicase
CAL13_RS19195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CAL13_RS19200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CAL13_RS19215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CAL13_RS19220	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CAL13_RS19225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CAL13_RS19235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CAL13_RS19250	COG0356	it plays a direct role in the translocation of protons across the membrane
CAL13_RS19265	COG1024	Enoyl-CoA hydratase
CAL13_RS19270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CAL13_RS19275	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CAL13_RS19295	COG0163	prenyltransferase activity
CAL13_RS19300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CAL13_RS19305	COG2890	protein-(glutamine-N5) methyltransferase activity
CAL13_RS19310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CAL13_RS19335	COG2818	Glycosylase
CAL13_RS19340	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CAL13_RS19345	COG1230	cation diffusion facilitator family transporter
CAL13_RS19370	COG3069	C4-dicarboxylate transmembrane transporter activity
CAL13_RS19375	COG1802	Transcriptional regulator
CAL13_RS19425	COG2943	transferase activity, transferring hexosyl groups
CAL13_RS19430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CAL13_RS19440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL13_RS19445	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CAL13_RS19450	COG2967	ApaG domain
CAL13_RS19455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CAL13_RS19460	COG0546	phosphoglycolate phosphatase activity
CAL13_RS19470	COG0512	Glutamine amidotransferase of anthranilate synthase
CAL13_RS19475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CAL13_RS19480	COG0134	indole-3-glycerol-phosphate synthase activity
CAL13_RS19485	COG1607	acyl-coa hydrolase
CAL13_RS19495	COG3387	PFAM Glycoside hydrolase 15-related
CAL13_RS19515	COG0235	Class ii aldolase
CAL13_RS19525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CAL13_RS19535	COG1309	transcriptional regulator
CAL13_RS19540	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL13_RS19555	COG3604	Transcriptional regulator
CAL13_RS19560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CAL13_RS19570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CAL13_RS19575	COG0793	Belongs to the peptidase S41A family
CAL13_RS19580	COG4942	peptidase
CAL13_RS19585	COG0588	phosphoglycerate mutase activity
CAL13_RS19600	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CAL13_RS19605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CAL13_RS19615	COG2124	cytochrome p450
CAL13_RS19625	COG1040	competence protein
CAL13_RS19630	COG2226	methyltransferase
CAL13_RS19635	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CAL13_RS19640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CAL13_RS19645	COG0569	domain protein
CAL13_RS19650	COG2204	response regulator
CAL13_RS19655	COG5000	phosphorelay sensor kinase activity
CAL13_RS19665	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CAL13_RS19675	COG2814	Major facilitator Superfamily
CAL13_RS19680	COG2944	sequence-specific DNA binding
CAL13_RS19685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CAL13_RS19715	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CAL13_RS19720	COG0242	peptide deformylase activity
CAL13_RS19725	COG0758	DNA mediated transformation
CAL13_RS19740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CAL13_RS19775	COG1022	Amp-dependent synthetase and ligase
CAL13_RS19805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS19815	COG1850	ribulose-bisphosphate carboxylase activity
CAL13_RS19825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CAL13_RS19830	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CAL13_RS19835	COG0583	DNA-binding transcription factor activity
CAL13_RS19845	COG0709	Synthesizes selenophosphate from selenide and ATP
CAL13_RS19860	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CAL13_RS19865	COG0513	Belongs to the DEAD box helicase family
CAL13_RS19885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CAL13_RS19890	COG2308	Evidence 4 Homologs of previously reported genes of
CAL13_RS19900	COG1305	Transglutaminase-like
CAL13_RS19915	COG1950	PFAM Membrane protein of
CAL13_RS19925	COG0438	transferase activity, transferring glycosyl groups
CAL13_RS19935	COG3177	Filamentation induced by cAMP protein fic
CAL13_RS19940	COG0596	Alpha beta hydrolase
CAL13_RS19945	COG0066	3-isopropylmalate dehydratase activity
CAL13_RS19955	COG0583	DNA-binding transcription factor activity
CAL13_RS19960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CAL13_RS19970	COG1560	Kdo2-lipid A biosynthetic process
CAL13_RS19975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CAL13_RS19985	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CAL13_RS19995	COG0803	Belongs to the bacterial solute-binding protein 9 family
CAL13_RS20015	COG0735	belongs to the Fur family
CAL13_RS20020	COG0523	cobalamin synthesis protein
CAL13_RS20030	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CAL13_RS20035	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CAL13_RS20045	COG2096	Adenosyltransferase
CAL13_RS20055	COG2080	2 iron, 2 sulfur cluster binding
CAL13_RS20060	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CAL13_RS20065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CAL13_RS20070	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CAL13_RS20080	COG0321	lipoyl(octanoyl) transferase activity
CAL13_RS20085	COG2921	Belongs to the UPF0250 family
CAL13_RS20095	COG1686	Belongs to the peptidase S11 family
CAL13_RS20120	COG1127	ABC transporter
CAL13_RS20125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CAL13_RS20135	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CAL13_RS20150	COG0859	PFAM glycosyl transferase family 9
CAL13_RS20165	COG0463	Glycosyl transferase, family 2
CAL13_RS20225	COG1216	Glycosyl transferase, family 2
CAL13_RS20235	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CAL13_RS20240	COG1091	dTDP-4-dehydrorhamnose reductase activity
CAL13_RS20250	COG0463	Glycosyl transferase, family 2
CAL13_RS20255	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CAL13_RS20270	COG0183	Belongs to the thiolase family
CAL13_RS20275	COG1024	Enoyl-CoA hydratase
CAL13_RS20275	COG1250	3-hydroxyacyl-CoA dehydrogenase
CAL13_RS20290	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CAL13_RS20310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS20320	COG2188	Transcriptional regulator
CAL13_RS20325	COG2301	Belongs to the HpcH HpaI aldolase family
CAL13_RS20330	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CAL13_RS20345	COG1137	ATPase activity
CAL13_RS20360	COG2301	Belongs to the HpcH HpaI aldolase family
CAL13_RS20375	COG0683	leucine binding
CAL13_RS20400	COG3473	Maleate cis-trans isomerase
CAL13_RS20405	COG0596	Alpha beta hydrolase
CAL13_RS20410	COG2309	aminopeptidase activity
CAL13_RS20415	COG1335	isochorismatase
CAL13_RS20420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CAL13_RS20445	COG1956	GAF domain-containing protein
CAL13_RS20450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CAL13_RS20465	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CAL13_RS20475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CAL13_RS20490	COG1177	transmembrane transport
CAL13_RS20495	COG1176	ABC-type spermidine putrescine transport system, permease component I
CAL13_RS20500	COG3842	ATPase activity
CAL13_RS20515	COG2271	Major facilitator Superfamily
CAL13_RS20520	COG4638	Rieske (2fe-2S)
CAL13_RS20530	COG2814	Major facilitator Superfamily
CAL13_RS20545	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CAL13_RS20550	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CAL13_RS20555	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CAL13_RS20565	COG1965	Belongs to the frataxin family
CAL13_RS20580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CAL13_RS20585	COG1333	cytochrome c biogenesis protein
CAL13_RS20595	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CAL13_RS20605	COG4232	protein-disulfide reductase activity
CAL13_RS20610	COG1324	tolerance protein
CAL13_RS20615	COG0203	ribosomal protein L17
CAL13_RS20620	COG0202	RNA polymerase activity
CAL13_RS20625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CAL13_RS20630	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CAL13_RS20635	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CAL13_RS20640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CAL13_RS20650	COG0201	protein transport
CAL13_RS20655	COG0200	Binds to the 23S rRNA
CAL13_RS20660	COG1841	ribosomal large subunit assembly
CAL13_RS20665	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CAL13_RS20670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CAL13_RS20675	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CAL13_RS20680	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CAL13_RS20685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CAL13_RS20690	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CAL13_RS20695	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CAL13_RS20700	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CAL13_RS20725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CAL13_RS20730	COG0255	Belongs to the universal ribosomal protein uL29 family
CAL13_RS20735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CAL13_RS20740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CAL13_RS20745	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CAL13_RS20750	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CAL13_RS20755	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CAL13_RS20760	COG0089	rRNA binding
CAL13_RS20770	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CAL13_RS20775	COG0051	transcription antitermination factor activity, RNA binding
CAL13_RS20780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL13_RS20785	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CAL13_RS20790	COG0049	tRNA binding
CAL13_RS20795	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CAL13_RS20845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CAL13_RS20850	COG0085	RNA polymerase activity
CAL13_RS20855	COG0222	ribosome binding
CAL13_RS20860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CAL13_RS20865	COG0081	regulation of translation
CAL13_RS20870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CAL13_RS20880	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CAL13_RS20890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CAL13_RS20915	COG0252	asparaginase activity
CAL13_RS20920	COG1475	DNA binding
CAL13_RS20930	COG1192	Involved in chromosome partitioning
CAL13_RS20935	COG0357	Ribosomal RNA small subunit methyltransferase G
CAL13_RS20940	COG0445	tRNA wobble uridine modification
CAL13_RS20945	COG1278	Cold shock
CAL13_RS20950	COG0436	Aminotransferase
CAL13_RS20955	COG1595	DNA-templated transcription, initiation
CAL13_RS20960	COG3712	iron ion homeostasis
CAL13_RS20965	COG4774	siderophore transport
CAL13_RS20985	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CAL13_RS20995	COG0601	transmembrane transport
CAL13_RS21000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CAL13_RS21005	COG0444	Belongs to the ABC transporter superfamily
CAL13_RS21010	COG4608	Belongs to the ABC transporter superfamily
CAL13_RS21020	COG1473	amidohydrolase
CAL13_RS21030	COG1960	acyl-CoA dehydrogenase activity
CAL13_RS21050	COG0583	DNA-binding transcription factor activity
CAL13_RS21055	COG0706	membrane insertase activity
CAL13_RS21060	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CAL13_RS21065	COG0594	ribonuclease P activity
CAL13_RS21070	COG0230	Belongs to the bacterial ribosomal protein bL34 family