locus-tag	class	description
CBR72_RS00025	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS00035	COG2030	dehydratase
CBR72_RS00050	COG1024	Enoyl-CoA hydratase
CBR72_RS00100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS00130	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS00135	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS00150	COG0583	DNA-binding transcription factor activity
CBR72_RS00155	COG0372	Belongs to the citrate synthase family
CBR72_RS00205	COG0701	Predicted permease
CBR72_RS00250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR72_RS00285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBR72_RS00295	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR72_RS00300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CBR72_RS00310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBR72_RS00315	COG3620	sequence-specific DNA binding
CBR72_RS00320	COG2233	PERMEase
CBR72_RS00350	COG0406	alpha-ribazole phosphatase activity
CBR72_RS00355	COG4221	oxidoreductase activity
CBR72_RS00365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBR72_RS00370	COG0505	Belongs to the CarA family
CBR72_RS00375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBR72_RS00385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR72_RS00395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR72_RS00400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS00405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBR72_RS00410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBR72_RS00415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBR72_RS00435	COG1074	ATP-dependent DNA helicase activity
CBR72_RS00455	COG1686	Belongs to the peptidase S11 family
CBR72_RS00465	COG0693	protein deglycase activity
CBR72_RS00475	COG4974	Belongs to the 'phage' integrase family
CBR72_RS00480	COG0583	DNA-binding transcription factor activity
CBR72_RS00485	COG0028	Belongs to the TPP enzyme family
CBR72_RS00490	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS00500	COG0028	Belongs to the TPP enzyme family
CBR72_RS00505	COG1126	abc transporter atp-binding protein
CBR72_RS00510	COG0765	amino acid transport
CBR72_RS00515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS00530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS00535	COG0009	L-threonylcarbamoyladenylate synthase
CBR72_RS00540	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBR72_RS00545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CBR72_RS00555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBR72_RS00565	COG1301	dicarboxylic acid transport
CBR72_RS00570	COG0456	acetyltransferase
CBR72_RS00600	COG3454	Phosphonate metabolism
CBR72_RS00605	COG4778	phosphonate C-P lyase system protein PhnL
CBR72_RS00610	COG4107	phosphonate C-P lyase system protein PhnK
CBR72_RS00615	COG3627	carbon phosphorus lyase activity
CBR72_RS00620	COG3626	phosphonate metabolism
CBR72_RS00630	COG3624	Phosphonate C-P lyase system protein PhnG
CBR72_RS00635	COG2188	Transcriptional regulator
CBR72_RS00640	COG3454	Phosphonate metabolism
CBR72_RS00650	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CBR72_RS00655	COG3639	organic phosphonate transmembrane transporter activity
CBR72_RS00660	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CBR72_RS00665	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR72_RS00670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR72_RS00680	COG0739	heme binding
CBR72_RS00690	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR72_RS00695	COG0306	phosphate transporter
CBR72_RS00740	COG0625	glutathione transferase activity
CBR72_RS00760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBR72_RS00765	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBR72_RS00775	COG0126	phosphoglycerate kinase activity
CBR72_RS00780	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBR72_RS00785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBR72_RS00790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CBR72_RS00805	COG0281	malic enzyme
CBR72_RS00805	COG0280	phosphate acetyltransferase
CBR72_RS00815	COG0436	Aminotransferase
CBR72_RS00820	COG0741	lytic transglycosylase activity
CBR72_RS00825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CBR72_RS00840	COG4575	ribosome binding
CBR72_RS00850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CBR72_RS00850	COG1648	precorrin-2 dehydrogenase activity
CBR72_RS00855	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBR72_RS00860	COG2027	D-alanyl-D-alanine carboxypeptidase
CBR72_RS00865	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBR72_RS00870	COG0343	queuine tRNA-ribosyltransferase activity
CBR72_RS00875	COG1862	Preprotein translocase
CBR72_RS00880	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR72_RS00885	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR72_RS00915	COG0667	Aldo Keto reductase
CBR72_RS00920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBR72_RS00925	COG4535	Mg2 and Co2 transporter CorC
CBR72_RS00930	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBR72_RS00935	COG1702	phosphate starvation-inducible protein PhoH
CBR72_RS00940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR72_RS00990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBR72_RS00995	COG0697	spore germination
CBR72_RS01005	COG0494	nUDIX hydrolase
CBR72_RS01015	COG0583	DNA-binding transcription factor activity
CBR72_RS01020	COG3530	Putative quorum-sensing-regulated virulence factor
CBR72_RS01030	COG2814	Major facilitator Superfamily
CBR72_RS01050	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS01055	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS01060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS01070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR72_RS01075	COG0583	DNA-binding transcription factor activity
CBR72_RS01115	COG2814	Major facilitator Superfamily
CBR72_RS01125	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CBR72_RS01135	COG0628	permease
CBR72_RS01140	COG0842	Transport permease protein
CBR72_RS01145	COG1131	(ABC) transporter
CBR72_RS01150	COG1764	response to oxidative stress
CBR72_RS01155	COG1846	Transcriptional regulator
CBR72_RS01170	COG0348	domain, Protein
CBR72_RS01190	COG3278	Belongs to the heme-copper respiratory oxidase family
CBR72_RS01200	COG2217	Heavy metal translocating P-type atpase
CBR72_RS01205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS01210	COG0156	8-amino-7-oxononanoate synthase activity
CBR72_RS01220	COG4106	trans-aconitate 2-methyltransferase activity
CBR72_RS01220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBR72_RS01225	COG2224	Isocitrate lyase
CBR72_RS01230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR72_RS01230	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR72_RS01240	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CBR72_RS01250	COG1472	Belongs to the glycosyl hydrolase 3 family
CBR72_RS01255	COG0736	holo-[acyl-carrier-protein] synthase activity
CBR72_RS01260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CBR72_RS01270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR72_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS01280	COG0745	RESPONSE REGULATOR receiver
CBR72_RS01300	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR72_RS01305	COG4149	molybdate abc transporter
CBR72_RS01310	COG0725	ABC transporter, periplasmic molybdate-binding protein
CBR72_RS01320	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS01330	COG0667	Aldo Keto reductase
CBR72_RS01335	COG2032	superoxide dismutase activity
CBR72_RS01345	COG0318	PFAM AMP-dependent synthetase and ligase
CBR72_RS01350	COG1024	Enoyl-CoA hydratase
CBR72_RS01360	COG1802	Transcriptional regulator
CBR72_RS01380	COG1217	gtp-binding protein TYPA
CBR72_RS01385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBR72_RS01390	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBR72_RS01395	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBR72_RS01400	COG2251	uridine kinase activity
CBR72_RS01400	COG0195	Participates in both transcription termination and antitermination
CBR72_RS01405	COG0779	Required for maturation of 30S ribosomal subunits
CBR72_RS01410	COG1187	pseudouridine synthase activity
CBR72_RS01415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBR72_RS01425	COG0583	DNA-binding transcription factor activity
CBR72_RS01430	COG0523	cobalamin synthesis protein
CBR72_RS01460	COG0625	glutathione transferase activity
CBR72_RS01465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBR72_RS01475	COG2003	Belongs to the UPF0758 family
CBR72_RS01480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CBR72_RS01485	COG3483	tryptophan 2,3-dioxygenase activity
CBR72_RS01490	COG0254	rRNA binding
CBR72_RS01525	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS01530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBR72_RS01540	COG1562	ergosterol biosynthetic process
CBR72_RS01545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR72_RS01545	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR72_RS01550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBR72_RS01575	COG1477	protein flavinylation
CBR72_RS01580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CBR72_RS01590	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR72_RS01600	COG0542	response to heat
CBR72_RS01610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBR72_RS01625	COG0678	peroxiredoxin activity
CBR72_RS01635	COG0412	Dienelactone hydrolase
CBR72_RS01645	COG0315	cyclic pyranopterin monophosphate synthase activity
CBR72_RS01655	COG0314	molybdopterin synthase activity
CBR72_RS01660	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR72_RS01665	COG0303	'Molybdopterin
CBR72_RS01670	COG0746	molybdenum cofactor guanylyltransferase activity
CBR72_RS01675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBR72_RS01695	COG3383	formate dehydrogenase (NAD+) activity
CBR72_RS01710	COG2264	protein methyltransferase activity
CBR72_RS01730	COG5006	permease, DMT superfamily
CBR72_RS01735	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS01785	COG1129	ABC transporter
CBR72_RS01795	COG1666	GTP binding
CBR72_RS01825	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR72_RS01830	COG1845	cytochrome c oxidase, subunit III
CBR72_RS01835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR72_RS01845	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CBR72_RS01870	COG0783	Belongs to the Dps family
CBR72_RS01885	COG1346	cytolysis
CBR72_RS01890	COG1380	Effector of murein hydrolase LrgA
CBR72_RS01895	COG0583	DNA-binding transcription factor activity
CBR72_RS01905	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS01910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS01915	COG0601	transmembrane transport
CBR72_RS01920	COG0747	negative chemotaxis
CBR72_RS01930	COG0598	Magnesium transport protein CorA
CBR72_RS01935	COG0210	DNA helicase
CBR72_RS01950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS01965	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR72_RS01975	COG1045	serine acetyltransferase
CBR72_RS01980	COG1309	transcriptional regulator
CBR72_RS01985	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS01995	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS01995	COG1024	Enoyl-CoA hydratase
CBR72_RS02000	COG2067	long-chain fatty acid transport protein
CBR72_RS02005	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS02005	COG1024	Enoyl-CoA hydratase
CBR72_RS02010	COG0183	Belongs to the thiolase family
CBR72_RS02025	COG0318	PFAM AMP-dependent synthetase and ligase
CBR72_RS02035	COG1902	pentaerythritol trinitrate reductase activity
CBR72_RS02060	COG0251	oxidation-reduction process
CBR72_RS02070	COG1832	CoA-binding protein
CBR72_RS02075	COG1414	Transcriptional regulator
CBR72_RS02095	COG4993	Dehydrogenase
CBR72_RS02105	COG4772	TonB-dependent receptor
CBR72_RS02110	COG2814	Major facilitator Superfamily
CBR72_RS02125	COG1132	(ABC) transporter
CBR72_RS02140	COG0037	tRNA processing
CBR72_RS02145	COG0825	malonyl-CoA metabolic process
CBR72_RS02155	COG0215	cysteine-tRNA ligase activity
CBR72_RS02165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBR72_RS02170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR72_RS02175	COG1968	undecaprenyl-diphosphatase activity
CBR72_RS02180	COG1253	flavin adenine dinucleotide binding
CBR72_RS02185	COG0483	inositol monophosphate 1-phosphatase activity
CBR72_RS02190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CBR72_RS02205	COG0668	transmembrane transport
CBR72_RS02230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR72_RS02240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR72_RS02275	COG3360	Dodecin
CBR72_RS02295	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBR72_RS02300	COG2850	peptidyl-arginine hydroxylation
CBR72_RS02310	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CBR72_RS02315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR72_RS02320	COG1994	Peptidase M50
CBR72_RS02325	COG0009	L-threonylcarbamoyladenylate synthase
CBR72_RS02330	COG2321	neutral zinc metallopeptidase
CBR72_RS02355	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR72_RS02360	COG0583	DNA-binding transcription factor activity
CBR72_RS02390	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR72_RS02400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR72_RS02410	COG2072	flavoprotein involved in K transport
CBR72_RS02415	COG3842	ATPase activity
CBR72_RS02420	COG4221	oxidoreductase activity
CBR72_RS02420	COG3321	synthase
CBR72_RS02420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR72_RS02420	COG0604	alcohol dehydrogenase
CBR72_RS02430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR72_RS02435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR72_RS02440	COG1177	transmembrane transport
CBR72_RS02445	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR72_RS02455	COG1126	abc transporter atp-binding protein
CBR72_RS02460	COG0765	amino acid transport
CBR72_RS02470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS02480	COG0251	oxidation-reduction process
CBR72_RS02495	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR72_RS02510	COG2020	methyltransferase activity
CBR72_RS02535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR72_RS02540	COG3608	succinylglutamate desuccinylase aspartoacylase
CBR72_RS02540	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBR72_RS02550	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS02580	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS02620	COG2202	Pas domain
CBR72_RS02620	COG2199	diguanylate cyclase activity
CBR72_RS02620	COG2200	EAL domain
CBR72_RS02625	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CBR72_RS02630	COG1414	Transcriptional regulator
CBR72_RS02650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS02680	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS02685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS02690	COG2186	Transcriptional regulator
CBR72_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS02745	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR72_RS02765	COG4604	ABC transporter, ATP-binding protein
CBR72_RS02770	COG4605	iron ion homeostasis
CBR72_RS02775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR72_RS02780	COG4607	ABC-type enterochelin transport system periplasmic component
CBR72_RS02785	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS02790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR72_RS02795	COG0149	triose-phosphate isomerase activity
CBR72_RS02800	COG4221	oxidoreductase activity
CBR72_RS02800	COG0604	alcohol dehydrogenase
CBR72_RS02800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR72_RS02800	COG3321	synthase
CBR72_RS02825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR72_RS02830	COG0583	DNA-binding transcription factor activity
CBR72_RS02860	COG1185	polyribonucleotide nucleotidyltransferase activity
CBR72_RS02865	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBR72_RS02875	COG1183	phosphatidylcholine synthase activity
CBR72_RS02880	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR72_RS02885	COG0440	acetolactate synthase activity
CBR72_RS02890	COG0028	Belongs to the TPP enzyme family
CBR72_RS02895	COG1289	transmembrane transporter activity
CBR72_RS02900	COG3022	response to hydroperoxide
CBR72_RS02905	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS02930	COG1309	transcriptional regulator
CBR72_RS02945	COG2186	Transcriptional regulator
CBR72_RS02950	COG4638	Rieske (2fe-2S)
CBR72_RS02955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CBR72_RS02960	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS03015	COG2095	MarC family integral membrane protein
CBR72_RS03025	COG3447	MASE1 domain protein
CBR72_RS03025	COG5001	Diguanylate cyclase
CBR72_RS03025	COG5002	protein histidine kinase activity
CBR72_RS03045	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBR72_RS03060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBR72_RS03075	COG0601	transmembrane transport
CBR72_RS03095	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBR72_RS03095	COG0517	IMP dehydrogenase activity
CBR72_RS03100	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR72_RS03110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CBR72_RS03115	COG1674	ftsk spoiiie
CBR72_RS03120	COG0492	ferredoxin-NADP+ reductase activity
CBR72_RS03125	COG1193	negative regulation of DNA recombination
CBR72_RS03135	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBR72_RS03150	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CBR72_RS03155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CBR72_RS03160	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CBR72_RS03165	COG2205	protein histidine kinase activity
CBR72_RS03170	COG0745	RESPONSE REGULATOR receiver
CBR72_RS03185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR72_RS03210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR72_RS03225	COG0612	Peptidase, M16
CBR72_RS03230	COG0484	heat shock protein binding
CBR72_RS03235	COG0443	Heat shock 70 kDa protein
CBR72_RS03245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBR72_RS03255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBR72_RS03260	COG1420	regulation of RNA biosynthetic process
CBR72_RS03265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CBR72_RS03270	COG0497	DNA recombination
CBR72_RS03275	COG0735	belongs to the Fur family
CBR72_RS03280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR72_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR72_RS03330	COG2828	Protein conserved in bacteria
CBR72_RS03335	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS03355	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CBR72_RS03360	COG1802	Transcriptional regulator
CBR72_RS03365	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR72_RS03370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBR72_RS03375	COG1335	isochorismatase
CBR72_RS03380	COG0523	cobalamin synthesis protein
CBR72_RS03415	COG0583	DNA-binding transcription factor activity
CBR72_RS03425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBR72_RS03430	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CBR72_RS03435	COG0167	dihydroorotate dehydrogenase activity
CBR72_RS03450	COG1414	Transcriptional regulator
CBR72_RS03455	COG1546	Belongs to the CinA family
CBR72_RS03455	COG1058	Belongs to the CinA family
CBR72_RS03470	COG0513	Belongs to the DEAD box helicase family
CBR72_RS03495	COG0429	hydrolase of the alpha beta-hydrolase fold
CBR72_RS03500	COG4783	chaperone-mediated protein folding
CBR72_RS03520	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBR72_RS03535	COG0006	proline dipeptidase activity
CBR72_RS03545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS03565	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CBR72_RS03570	COG0632	four-way junction helicase activity
CBR72_RS03580	COG0702	epimerase
CBR72_RS03585	COG2255	four-way junction helicase activity
CBR72_RS03590	COG0514	ATP-dependent DNA helicase (RecQ)
CBR72_RS03610	COG1294	oxidase, subunit
CBR72_RS03620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR72_RS03625	COG0850	regulation of cytokinetic process
CBR72_RS03630	COG2894	cell division
CBR72_RS03635	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBR72_RS03650	COG0488	(ABC) transporter
CBR72_RS03665	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS03670	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS03675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS03680	COG0601	transmembrane transport
CBR72_RS03690	COG1215	transferase activity, transferring glycosyl groups
CBR72_RS03695	COG0583	DNA-binding transcription factor activity
CBR72_RS03700	COG1802	Transcriptional regulator
CBR72_RS03705	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS03715	COG1024	Enoyl-CoA hydratase
CBR72_RS03740	COG1137	ATPase activity
CBR72_RS03750	COG0154	amidase activity
CBR72_RS03755	COG1368	sulfuric ester hydrolase activity
CBR72_RS03765	COG3685	Protein conserved in bacteria
CBR72_RS03775	COG1686	Belongs to the peptidase S11 family
CBR72_RS03795	COG2832	Protein of unknown function (DUF454)
CBR72_RS03810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR72_RS03840	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBR72_RS03845	COG1802	Transcriptional regulator
CBR72_RS03850	COG0747	negative chemotaxis
CBR72_RS03855	COG0601	transmembrane transport
CBR72_RS03860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS03865	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS03870	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS03880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR72_RS03905	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS03910	COG1396	sequence-specific DNA binding
CBR72_RS03920	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR72_RS03925	COG3842	ATPase activity
CBR72_RS03935	COG4191	Histidine kinase
CBR72_RS03935	COG0745	RESPONSE REGULATOR receiver
CBR72_RS03935	COG2205	protein histidine kinase activity
CBR72_RS03940	COG4566	intracellular signal transduction
CBR72_RS03965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR72_RS03970	COG0477	Major facilitator Superfamily
CBR72_RS03975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS03985	COG0583	DNA-binding transcription factor activity
CBR72_RS03990	COG1414	Transcriptional regulator
CBR72_RS03995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS04000	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR72_RS04005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR72_RS04010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR72_RS04015	COG0583	DNA-binding transcription factor activity
CBR72_RS04020	COG3485	protocatechuate 3,4-dioxygenase
CBR72_RS04025	COG3485	protocatechuate 3,4-dioxygenase
CBR72_RS04035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR72_RS04055	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS04070	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS04085	COG0683	leucine binding
CBR72_RS04110	COG0028	Belongs to the TPP enzyme family
CBR72_RS04115	COG1802	Transcriptional regulator
CBR72_RS04120	COG1802	Transcriptional regulator
CBR72_RS04125	COG0513	Belongs to the DEAD box helicase family
CBR72_RS04135	COG1595	DNA-templated transcription, initiation
CBR72_RS04145	COG0583	DNA-binding transcription factor activity
CBR72_RS04175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS04200	COG0657	acetylesterase activity
CBR72_RS04210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR72_RS04215	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CBR72_RS04225	COG3971	2-oxopent-4-enoate hydratase activity
CBR72_RS04260	COG0459	protein refolding
CBR72_RS04280	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS04300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBR72_RS04305	COG0459	protein refolding
CBR72_RS04315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBR72_RS04320	COG1252	NADH dehydrogenase
CBR72_RS04325	COG0284	orotidine-5'-phosphate decarboxylase activity
CBR72_RS04335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBR72_RS04345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR72_RS04350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBR72_RS04425	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR72_RS04430	COG3639	organic phosphonate transmembrane transporter activity
CBR72_RS04435	COG3639	organic phosphonate transmembrane transporter activity
CBR72_RS04450	COG0742	ribosomal rna small subunit methyltransferase
CBR72_RS04455	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBR72_RS04460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBR72_RS04465	COG3135	benzoate transporter
CBR72_RS04505	COG2188	Transcriptional regulator
CBR72_RS04510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS04515	COG1024	Enoyl-CoA hydratase
CBR72_RS04520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR72_RS04540	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS04545	COG2814	Major facilitator Superfamily
CBR72_RS04565	COG0012	GTP binding
CBR72_RS04575	COG0193	aminoacyl-tRNA hydrolase activity
CBR72_RS04580	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBR72_RS04585	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBR72_RS04595	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBR72_RS04600	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CBR72_RS04610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBR72_RS04620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS04635	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR72_RS04645	COG1368	sulfuric ester hydrolase activity
CBR72_RS04650	COG2186	Transcriptional regulator
CBR72_RS04655	COG5002	protein histidine kinase activity
CBR72_RS04655	COG5000	phosphorelay sensor kinase activity
CBR72_RS04660	COG0745	RESPONSE REGULATOR receiver
CBR72_RS04665	COG0277	FAD linked oxidase domain protein
CBR72_RS04680	COG0166	Belongs to the GPI family
CBR72_RS04685	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS04690	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS04705	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS04720	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR72_RS04725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR72_RS04730	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CBR72_RS04750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR72_RS04755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS04770	COG0747	negative chemotaxis
CBR72_RS04775	COG0601	transmembrane transport
CBR72_RS04780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS04785	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS04800	COG5339	Protein conserved in bacteria
CBR72_RS04805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR72_RS04805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR72_RS04810	COG0509	glycine decarboxylation via glycine cleavage system
CBR72_RS04815	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CBR72_RS04825	COG0371	Dehydrogenase
CBR72_RS04850	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS04865	COG2081	HI0933 family
CBR72_RS04880	COG0456	acetyltransferase
CBR72_RS04880	COG1214	PFAM Peptidase M22, glycoprotease
CBR72_RS04885	COG0717	Belongs to the dCTP deaminase family
CBR72_RS04900	COG0489	protein tyrosine kinase activity
CBR72_RS04910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR72_RS04910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR72_RS04915	COG1054	Belongs to the UPF0176 family
CBR72_RS04930	COG2194	sulfuric ester hydrolase activity
CBR72_RS04950	COG3539	Fimbrial protein
CBR72_RS04955	COG0010	Belongs to the arginase family
CBR72_RS04970	COG3842	ATPase activity
CBR72_RS04975	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR72_RS04980	COG1177	transmembrane transport
CBR72_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS05020	COG2084	Dehydrogenase
CBR72_RS05025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR72_RS05060	COG2226	methyltransferase
CBR72_RS05060	COG1073	alpha beta
CBR72_RS05080	COG2423	ornithine cyclodeaminase activity
CBR72_RS05095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS05125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS05130	COG0765	amino acid transport
CBR72_RS05135	COG0765	amino acid transport
CBR72_RS05145	COG0583	DNA-binding transcription factor activity
CBR72_RS05150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR72_RS05155	COG2755	lipolytic protein G-D-S-L family
CBR72_RS05155	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS05160	COG0625	glutathione transferase activity
CBR72_RS05180	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR72_RS05185	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS05190	COG1309	transcriptional regulator
CBR72_RS05225	COG1309	transcriptional regulator
CBR72_RS05230	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS05235	COG0583	DNA-binding transcription factor activity
CBR72_RS05240	COG2072	flavoprotein involved in K transport
CBR72_RS05285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR72_RS05285	COG0426	domain, Protein
CBR72_RS05290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR72_RS05295	COG0583	DNA-binding transcription factor activity
CBR72_RS05300	COG3386	PFAM SMP-30 Gluconolaconase
CBR72_RS05305	COG1024	Enoyl-CoA hydratase
CBR72_RS05315	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS05345	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS05350	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS05355	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR72_RS05360	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS05365	COG0583	DNA-binding transcription factor activity
CBR72_RS05430	COG1192	Involved in chromosome partitioning
CBR72_RS05455	COG3077	Addiction module antitoxin, RelB DinJ family
CBR72_RS05485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBR72_RS05500	COG0798	PFAM Bile acid sodium symporter
CBR72_RS05515	COG0640	Transcriptional regulator
CBR72_RS05625	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CBR72_RS05635	COG1404	Belongs to the peptidase S8 family
CBR72_RS05640	COG0464	growth
CBR72_RS05645	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBR72_RS05745	COG1917	Cupin 2, conserved barrel domain protein
CBR72_RS05780	COG0583	DNA-binding transcription factor activity
CBR72_RS05790	COG0583	DNA-binding transcription factor activity
CBR72_RS05795	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS05805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBR72_RS05810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR72_RS05810	COG0519	Catalyzes the synthesis of GMP from XMP
CBR72_RS05825	COG0583	DNA-binding transcription factor activity
CBR72_RS05830	COG0384	phenazine biosynthesis protein PhzF
CBR72_RS05835	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS05850	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS05860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS05885	COG0024	Methionine aminopeptidase
CBR72_RS05950	COG0582	viral genome integration into host DNA
CBR72_RS05965	COG0277	FAD linked oxidase domain protein
CBR72_RS05970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR72_RS05975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR72_RS06000	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS06005	COG0583	DNA-binding transcription factor activity
CBR72_RS06015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBR72_RS06030	COG1652	LysM domain
CBR72_RS06035	COG0560	Phosphoserine phosphatase
CBR72_RS06040	COG0583	DNA-binding transcription factor activity
CBR72_RS06045	COG3842	ATPase activity
CBR72_RS06050	COG1178	ABC-type Fe3 transport system permease component
CBR72_RS06060	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBR72_RS06065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR72_RS06080	COG0625	glutathione transferase activity
CBR72_RS06110	COG4336	lyase activity
CBR72_RS06120	COG1414	Transcriptional regulator
CBR72_RS06125	COG3734	2-keto-3-deoxy-galactonokinase
CBR72_RS06130	COG0800	Aldolase
CBR72_RS06135	COG4948	Mandelate Racemase Muconate Lactonizing
CBR72_RS06140	COG2271	Major facilitator Superfamily
CBR72_RS06145	COG0326	Molecular chaperone. Has ATPase activity
CBR72_RS06150	COG2233	PERMEase
CBR72_RS06185	COG0583	DNA-binding transcription factor activity
CBR72_RS06190	COG0235	Class ii aldolase
CBR72_RS06200	COG0436	Aminotransferase
CBR72_RS06280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBR72_RS06285	COG4774	siderophore transport
CBR72_RS06290	COG3712	iron ion homeostasis
CBR72_RS06295	COG1595	DNA-templated transcription, initiation
CBR72_RS06300	COG5285	phytanoyl-CoA dioxygenase
CBR72_RS06305	COG0628	permease
CBR72_RS06310	COG0583	DNA-binding transcription factor activity
CBR72_RS06315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS06335	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CBR72_RS06345	COG3539	Fimbrial protein
CBR72_RS06350	COG0129	dihydroxy-acid dehydratase activity
CBR72_RS06370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBR72_RS06375	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CBR72_RS06380	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS06385	COG2031	fatty acid transporter
CBR72_RS06390	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS06395	COG1414	Transcriptional regulator
CBR72_RS06405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CBR72_RS06410	COG4829	muconolactone delta-isomerase
CBR72_RS06420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR72_RS06440	COG0288	reversible hydration of carbon dioxide
CBR72_RS06445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR72_RS06465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CBR72_RS06470	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR72_RS06475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBR72_RS06480	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CBR72_RS06565	COG0659	secondary active sulfate transmembrane transporter activity
CBR72_RS06595	COG0683	leucine binding
CBR72_RS06600	COG0154	amidase activity
CBR72_RS06710	COG0142	geranyltranstransferase activity
CBR72_RS06715	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBR72_RS06720	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBR72_RS06725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBR72_RS06730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CBR72_RS06750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR72_RS06750	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR72_RS06755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBR72_RS06770	COG0861	Integral membrane protein TerC family
CBR72_RS06775	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS06790	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBR72_RS06795	COG0793	Belongs to the peptidase S41A family
CBR72_RS06800	COG4942	peptidase
CBR72_RS06805	COG0588	phosphoglycerate mutase activity
CBR72_RS06815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR72_RS06820	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBR72_RS06825	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBR72_RS06845	COG2226	methyltransferase
CBR72_RS06850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CBR72_RS06855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CBR72_RS06860	COG0569	domain protein
CBR72_RS06865	COG2204	response regulator
CBR72_RS06870	COG5000	phosphorelay sensor kinase activity
CBR72_RS06880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR72_RS06880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR72_RS06890	COG0583	DNA-binding transcription factor activity
CBR72_RS06895	COG2814	Major facilitator Superfamily
CBR72_RS06900	COG0583	DNA-binding transcription factor activity
CBR72_RS06910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR72_RS06915	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS06920	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS06925	COG2072	flavoprotein involved in K transport
CBR72_RS06930	COG2267	carboxylic ester hydrolase activity
CBR72_RS06960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR72_RS06965	COG0583	DNA-binding transcription factor activity
CBR72_RS06970	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS07000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS07005	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR72_RS07020	COG0546	phosphoglycolate phosphatase activity
CBR72_RS07030	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR72_RS07035	COG0242	peptide deformylase activity
CBR72_RS07045	COG1522	sequence-specific DNA binding
CBR72_RS07050	COG2879	small protein
CBR72_RS07055	COG1966	Carbon starvation protein
CBR72_RS07070	COG0758	DNA mediated transformation
CBR72_RS07085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS07090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR72_RS07095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBR72_RS07165	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS07200	COG0640	Transcriptional regulator
CBR72_RS07235	COG0735	belongs to the Fur family
CBR72_RS07240	COG2207	Transcriptional regulator
CBR72_RS07255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR72_RS07260	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBR72_RS07285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBR72_RS07290	COG2308	Evidence 4 Homologs of previously reported genes of
CBR72_RS07300	COG1305	Transglutaminase-like
CBR72_RS07320	COG3220	belongs to the UPF0276 family
CBR72_RS07335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBR72_RS07340	COG1950	PFAM Membrane protein of
CBR72_RS07350	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS07365	COG0066	3-isopropylmalate dehydratase activity
CBR72_RS07380	COG0583	DNA-binding transcription factor activity
CBR72_RS07385	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBR72_RS07395	COG1560	Kdo2-lipid A biosynthetic process
CBR72_RS07400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBR72_RS07410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CBR72_RS07435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBR72_RS07445	COG0735	belongs to the Fur family
CBR72_RS07450	COG0523	cobalamin synthesis protein
CBR72_RS07460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBR72_RS07465	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBR72_RS07475	COG2096	Adenosyltransferase
CBR72_RS07480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CBR72_RS07485	COG0321	lipoyl(octanoyl) transferase activity
CBR72_RS07490	COG2921	Belongs to the UPF0250 family
CBR72_RS07500	COG1686	Belongs to the peptidase S11 family
CBR72_RS07520	COG1127	ABC transporter
CBR72_RS07525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR72_RS07535	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBR72_RS07545	COG0859	PFAM glycosyl transferase family 9
CBR72_RS07580	COG0477	Major facilitator Superfamily
CBR72_RS07590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR72_RS07595	COG3568	Endonuclease Exonuclease Phosphatase
CBR72_RS07600	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBR72_RS07630	COG0531	amino acid
CBR72_RS07635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR72_RS07640	COG1956	GAF domain-containing protein
CBR72_RS07645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR72_RS07650	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CBR72_RS07660	COG1129	ABC transporter
CBR72_RS07670	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS07680	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS07690	COG2186	Transcriptional regulator
CBR72_RS07695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CBR72_RS07700	COG3842	ATPase activity
CBR72_RS07705	COG1175	transmembrane transport
CBR72_RS07755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBR72_RS07760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR72_RS07780	COG0367	asparagine synthase
CBR72_RS07785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBR72_RS07790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBR72_RS07800	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBR72_RS07815	COG2226	methyltransferase
CBR72_RS07820	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS07825	COG0367	asparagine synthase
CBR72_RS07830	COG0367	asparagine synthase
CBR72_RS07845	COG2814	Major facilitator Superfamily
CBR72_RS07865	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CBR72_RS07870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBR72_RS07875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR72_RS07885	COG1965	Belongs to the frataxin family
CBR72_RS07900	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR72_RS07905	COG1333	cytochrome c biogenesis protein
CBR72_RS07915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBR72_RS07930	COG4232	protein-disulfide reductase activity
CBR72_RS07935	COG1324	tolerance protein
CBR72_RS07945	COG0203	ribosomal protein L17
CBR72_RS07950	COG0202	RNA polymerase activity
CBR72_RS07955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBR72_RS07960	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBR72_RS07965	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBR72_RS07970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBR72_RS07975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR72_RS07980	COG0201	protein transport
CBR72_RS07985	COG0200	Binds to the 23S rRNA
CBR72_RS07990	COG1841	ribosomal large subunit assembly
CBR72_RS07995	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBR72_RS08000	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBR72_RS08005	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBR72_RS08010	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBR72_RS08015	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBR72_RS08020	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBR72_RS08025	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBR72_RS08030	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBR72_RS08055	COG2267	carboxylic ester hydrolase activity
CBR72_RS08070	COG1131	(ABC) transporter
CBR72_RS08085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBR72_RS08090	COG0255	Belongs to the universal ribosomal protein uL29 family
CBR72_RS08095	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBR72_RS08100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBR72_RS08105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBR72_RS08110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBR72_RS08115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBR72_RS08120	COG0089	rRNA binding
CBR72_RS08125	COG0088	Forms part of the polypeptide exit tunnel
CBR72_RS08130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBR72_RS08135	COG0051	transcription antitermination factor activity, RNA binding
CBR72_RS08140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR72_RS08145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR72_RS08150	COG0049	tRNA binding
CBR72_RS08155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBR72_RS08190	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBR72_RS08195	COG0085	RNA polymerase activity
CBR72_RS08200	COG0222	ribosome binding
CBR72_RS08205	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBR72_RS08210	COG0081	regulation of translation
CBR72_RS08215	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBR72_RS08225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR72_RS08235	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR72_RS08255	COG0252	asparaginase activity
CBR72_RS08260	COG1475	DNA binding
CBR72_RS08265	COG1192	Involved in chromosome partitioning
CBR72_RS08270	COG0357	Ribosomal RNA small subunit methyltransferase G
CBR72_RS08275	COG0445	tRNA wobble uridine modification
CBR72_RS08280	COG1278	Cold shock
CBR72_RS08285	COG0436	Aminotransferase
CBR72_RS08295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR72_RS08300	COG0583	DNA-binding transcription factor activity
CBR72_RS08350	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS08355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS08365	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR72_RS08375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR72_RS08385	COG1505	serine-type exopeptidase activity
CBR72_RS08390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR72_RS08400	COG0601	transmembrane transport
CBR72_RS08405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS08410	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS08415	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS08420	COG1473	amidohydrolase
CBR72_RS08425	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CBR72_RS08430	COG0706	membrane insertase activity
CBR72_RS08435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBR72_RS08440	COG0594	ribonuclease P activity
CBR72_RS08445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBR72_RS08450	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBR72_RS08470	COG1309	transcriptional regulator
CBR72_RS08475	COG1254	Belongs to the acylphosphatase family
CBR72_RS08480	COG1304	FMN binding
CBR72_RS08485	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CBR72_RS08500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS08505	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS08530	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS08535	COG0583	DNA-binding transcription factor activity
CBR72_RS08540	COG0625	glutathione transferase activity
CBR72_RS08545	COG0402	S-adenosylhomocysteine deaminase activity
CBR72_RS08550	COG1079	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS08555	COG4603	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS08560	COG3845	ABC transporter
CBR72_RS08575	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR72_RS08580	COG2910	NAD(P)H-binding
CBR72_RS08600	COG0702	epimerase
CBR72_RS08610	COG3781	membrane
CBR72_RS08615	COG1522	sequence-specific DNA binding
CBR72_RS08620	COG0028	Belongs to the TPP enzyme family
CBR72_RS08630	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS08635	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS08640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR72_RS08645	COG3842	ATPase activity
CBR72_RS08665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR72_RS08670	COG2922	Belongs to the Smg family
CBR72_RS08675	COG1629	transport
CBR72_RS08695	COG2358	TRAP transporter, solute receptor (TAXI family
CBR72_RS08705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR72_RS08720	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CBR72_RS08725	COG0183	Belongs to the thiolase family
CBR72_RS08730	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS08735	COG1473	amidohydrolase
CBR72_RS08765	COG2200	EAL domain
CBR72_RS08770	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR72_RS08780	COG0018	arginyl-trna synthetase
CBR72_RS08795	COG0395	ABC-type sugar transport system, permease component
CBR72_RS08800	COG1175	transmembrane transport
CBR72_RS08805	COG1653	transport
CBR72_RS08810	COG3842	ATPase activity
CBR72_RS08815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR72_RS08820	COG3842	ATPase activity
CBR72_RS08845	COG0154	amidase activity
CBR72_RS08850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR72_RS08860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR72_RS08870	COG0583	DNA-binding transcription factor activity
CBR72_RS08890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBR72_RS08895	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS08900	COG0513	Belongs to the DEAD box helicase family
CBR72_RS08910	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CBR72_RS08920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS08925	COG0601	transmembrane transport
CBR72_RS08935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR72_RS08955	COG0697	spore germination
CBR72_RS08970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR72_RS08980	COG2969	positive regulation of protein catabolic process
CBR72_RS08985	COG0625	glutathione transferase activity
CBR72_RS08990	COG2857	Cytochrome c1
CBR72_RS08995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBR72_RS09000	COG0723	plastoquinol--plastocyanin reductase activity
CBR72_RS09005	COG1970	mechanosensitive ion channel activity
CBR72_RS09010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBR72_RS09015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR72_RS09025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR72_RS09030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR72_RS09035	COG0537	adenosine 5'-monophosphoramidase activity
CBR72_RS09040	COG0140	phosphoribosyl-ATP diphosphatase activity
CBR72_RS09045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBR72_RS09050	COG0107	imidazoleglycerol-phosphate synthase activity
CBR72_RS09055	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBR72_RS09065	COG0131	Imidazoleglycerol-phosphate dehydratase
CBR72_RS09070	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR72_RS09075	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBR72_RS09080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBR72_RS09085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBR72_RS09095	COG0842	Transport permease protein
CBR72_RS09100	COG1131	(ABC) transporter
CBR72_RS09115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CBR72_RS09120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR72_RS09125	COG1127	ABC transporter
CBR72_RS09130	COG3047	cAMP biosynthetic process
CBR72_RS09140	COG0069	glutamate synthase activity
CBR72_RS09140	COG0067	glutamate synthase
CBR72_RS09140	COG0070	glutamate synthase
CBR72_RS09155	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CBR72_RS09170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBR72_RS09175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR72_RS09185	COG1609	Transcriptional regulator
CBR72_RS09190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CBR72_RS09200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR72_RS09240	COG0109	protoheme IX farnesyltransferase activity
CBR72_RS09245	COG1999	signal sequence binding
CBR72_RS09265	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR72_RS09270	COG2814	Major facilitator Superfamily
CBR72_RS09285	COG1522	sequence-specific DNA binding
CBR72_RS09380	COG2124	cytochrome p450
CBR72_RS09415	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS09425	COG1902	pentaerythritol trinitrate reductase activity
CBR72_RS09500	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR72_RS09510	COG1671	Belongs to the UPF0178 family
CBR72_RS09515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS09540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBR72_RS09545	COG0443	Heat shock 70 kDa protein
CBR72_RS09555	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS09580	COG2169	Transcriptional regulator
CBR72_RS09580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBR72_RS09595	COG0583	DNA-binding transcription factor activity
CBR72_RS09605	COG1473	amidohydrolase
CBR72_RS09610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR72_RS09615	COG1335	isochorismatase
CBR72_RS09625	COG1683	Conserved Protein
CBR72_RS09630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS09645	COG1120	ATPase activity
CBR72_RS09650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR72_RS09655	COG4558	Periplasmic binding protein
CBR72_RS09660	COG3720	iron ion transport
CBR72_RS09670	COG3712	iron ion homeostasis
CBR72_RS09675	COG1595	DNA-templated transcription, initiation
CBR72_RS09705	COG1607	acyl-coa hydrolase
CBR72_RS09720	COG0437	4 iron, 4 sulfur cluster binding
CBR72_RS09725	COG2864	formate dehydrogenase
CBR72_RS09740	COG3276	selenocysteine insertion sequence binding
CBR72_RS09760	COG0583	DNA-binding transcription factor activity
CBR72_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS09780	COG0134	indole-3-glycerol-phosphate synthase activity
CBR72_RS09785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBR72_RS09790	COG0512	Glutamine amidotransferase of anthranilate synthase
CBR72_RS09800	COG0546	phosphoglycolate phosphatase activity
CBR72_RS09805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBR72_RS09810	COG2967	ApaG domain
CBR72_RS09815	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CBR72_RS09820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS09825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR72_RS09835	COG0037	tRNA processing
CBR72_RS09855	COG1024	Enoyl-CoA hydratase
CBR72_RS09870	COG0356	it plays a direct role in the translocation of protons across the membrane
CBR72_RS09880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBR72_RS09885	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBR72_RS09890	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBR72_RS09895	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBR72_RS09900	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBR72_RS09905	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBR72_RS09915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBR72_RS09920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBR72_RS09925	COG0210	DNA helicase
CBR72_RS09940	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS09945	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS09950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS09955	COG0601	transmembrane transport
CBR72_RS09965	COG0747	negative chemotaxis
CBR72_RS09975	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBR72_RS09980	COG1024	Enoyl-CoA hydratase
CBR72_RS09985	COG1024	Enoyl-CoA hydratase
CBR72_RS09990	COG2070	2-Nitropropane dioxygenase
CBR72_RS09995	COG1309	transcriptional regulator
CBR72_RS10000	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS10005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS10010	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS10015	COG3245	cytochrome
CBR72_RS10040	COG2918	glutathione biosynthetic process
CBR72_RS10060	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR72_RS10065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR72_RS10070	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR72_RS10070	COG2813	Specifically methylates the guanine in position
CBR72_RS10075	COG2223	nitrite transmembrane transporter activity
CBR72_RS10080	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS10090	COG2860	membrane
CBR72_RS10095	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR72_RS10100	COG0708	Exodeoxyribonuclease III
CBR72_RS10105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBR72_RS10110	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR72_RS10115	COG0154	amidase activity
CBR72_RS10120	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR72_RS10125	COG1077	Cell shape determining protein MreB Mrl
CBR72_RS10130	COG1792	Involved in formation and maintenance of cell shape
CBR72_RS10140	COG0768	penicillin binding
CBR72_RS10145	COG0772	Belongs to the SEDS family
CBR72_RS10150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR72_RS10155	COG0471	metal ion transport
CBR72_RS10160	COG1309	transcriptional regulator
CBR72_RS10170	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR72_RS10185	COG2823	Periplasmic or secreted lipoprotein
CBR72_RS10190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CBR72_RS10195	COG0792	nuclease activity
CBR72_RS10215	COG1660	Displays ATPase and GTPase activities
CBR72_RS10230	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CBR72_RS10240	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBR72_RS10245	COG1137	ATPase activity
CBR72_RS10260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CBR72_RS10270	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CBR72_RS10285	COG1294	oxidase, subunit
CBR72_RS10295	COG4988	ABC transporter
CBR72_RS10300	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBR72_RS10305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR72_RS10320	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS10325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR72_RS10330	COG1238	metal cluster binding
CBR72_RS10340	COG1802	Transcriptional regulator
CBR72_RS10350	COG1984	allophanate hydrolase subunit 2
CBR72_RS10355	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CBR72_RS10370	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR72_RS10385	COG2132	Multicopper oxidase
CBR72_RS10395	COG5002	protein histidine kinase activity
CBR72_RS10405	COG5002	protein histidine kinase activity
CBR72_RS10410	COG0745	RESPONSE REGULATOR receiver
CBR72_RS10415	COG2226	methyltransferase
CBR72_RS10430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR72_RS10435	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS10470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR72_RS10505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR72_RS10520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBR72_RS10530	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBR72_RS10535	COG1538	Outer membrane efflux protein
CBR72_RS10540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR72_RS10545	COG0351	phosphomethylpyrimidine kinase
CBR72_RS10550	COG2022	thiamine diphosphate biosynthetic process
CBR72_RS10555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBR72_RS10560	COG4206	TonB-dependent receptor
CBR72_RS10570	COG2226	methyltransferase
CBR72_RS10585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR72_RS10600	COG1194	a g-specific adenine glycosylase
CBR72_RS10610	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CBR72_RS10615	COG2177	Part of the ABC transporter FtsEX involved in
CBR72_RS10620	COG2884	Cell division ATP-binding protein ftsE
CBR72_RS10625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS10630	COG4597	amino acid ABC transporter
CBR72_RS10635	COG0765	amino acid transport
CBR72_RS10640	COG1126	abc transporter atp-binding protein
CBR72_RS10660	COG0477	Major facilitator Superfamily
CBR72_RS10670	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CBR72_RS10675	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBR72_RS10690	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBR72_RS10695	COG0237	dephospho-CoA kinase activity
CBR72_RS10700	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CBR72_RS10725	COG3539	Fimbrial protein
CBR72_RS10730	COG2816	NAD+ diphosphatase activity
CBR72_RS10740	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBR72_RS10775	COG0411	ABC transporter
CBR72_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS10815	COG1024	Enoyl-CoA hydratase
CBR72_RS10845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR72_RS10850	COG0352	thiamine-phosphate diphosphorylase activity
CBR72_RS10865	COG1678	Uncharacterized ACR, COG1678
CBR72_RS10870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBR72_RS10895	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR72_RS10905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBR72_RS10910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBR72_RS10920	COG0557	exoribonuclease II activity
CBR72_RS10925	COG3150	esterase
CBR72_RS10930	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR72_RS10940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR72_RS10945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR72_RS10950	COG0511	ligase activity, forming carbon-carbon bonds
CBR72_RS10955	COG0439	Biotin carboxylase
CBR72_RS10960	COG2264	protein methyltransferase activity
CBR72_RS10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBR72_RS10995	COG1696	Membrane protein involved in D-alanine export
CBR72_RS11000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR72_RS11030	COG1522	sequence-specific DNA binding
CBR72_RS11040	COG2814	Major facilitator Superfamily
CBR72_RS11045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR72_RS11050	COG1042	CoA-binding domain protein
CBR72_RS11050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR72_RS11050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR72_RS11050	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR72_RS11050	COG1042	CoA-binding domain protein
CBR72_RS11050	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR72_RS11100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR72_RS11125	COG3028	Belongs to the UPF0307 family
CBR72_RS11130	COG0312	modulator of DNA gyrase
CBR72_RS11140	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR72_RS11145	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBR72_RS11150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBR72_RS11155	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR72_RS11165	COG0316	Belongs to the HesB IscA family
CBR72_RS11170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CBR72_RS11180	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBR72_RS11190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBR72_RS11195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBR72_RS11205	COG1335	isochorismatase
CBR72_RS11210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR72_RS11210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR72_RS11220	COG2766	serine protein kinase
CBR72_RS11225	COG2718	Belongs to the UPF0229 family
CBR72_RS11230	COG2719	SpoVR family
CBR72_RS11250	COG4948	Mandelate Racemase Muconate Lactonizing
CBR72_RS11265	COG0477	Major facilitator Superfamily
CBR72_RS11275	COG0583	DNA-binding transcription factor activity
CBR72_RS11290	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR72_RS11295	COG0251	oxidation-reduction process
CBR72_RS11300	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CBR72_RS11305	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CBR72_RS11320	COG0165	Argininosuccinate lyase
CBR72_RS11330	COG3707	response regulator
CBR72_RS11340	COG0515	serine threonine protein kinase
CBR72_RS11345	COG2116	formate transmembrane transporter activity
CBR72_RS11355	COG2146	nitrite reductase [NAD(P)H] activity
CBR72_RS11355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBR72_RS11365	COG0589	response to stress
CBR72_RS11380	COG2816	NAD+ diphosphatase activity
CBR72_RS11385	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS11425	COG2979	Protein of unknown function (DUF533)
CBR72_RS11435	COG0741	lytic transglycosylase activity
CBR72_RS11435	COG1388	LysM domain
CBR72_RS11440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBR72_RS11445	COG2226	methyltransferase
CBR72_RS11450	COG0328	RNA-DNA hybrid ribonuclease activity
CBR72_RS11460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR72_RS11465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBR72_RS11475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS11480	COG0842	Transport permease protein
CBR72_RS11480	COG1129	ABC transporter
CBR72_RS11485	COG0842	Transport permease protein
CBR72_RS11505	COG0463	Glycosyl transferase, family 2
CBR72_RS11510	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBR72_RS11525	COG1073	alpha beta
CBR72_RS11535	COG0697	spore germination
CBR72_RS11540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR72_RS11555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR72_RS11565	COG1522	sequence-specific DNA binding
CBR72_RS11590	COG0823	Involved in the tonB-independent uptake of proteins
CBR72_RS11600	COG0848	biopolymer transport protein
CBR72_RS11605	COG0811	peptide transport
CBR72_RS11610	COG0824	Thioesterase
CBR72_RS11615	COG0442	prolyl-tRNA aminoacylation
CBR72_RS11645	COG1414	Transcriptional regulator
CBR72_RS11650	COG1024	Enoyl-CoA hydratase
CBR72_RS11665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBR72_RS11670	COG2084	Dehydrogenase
CBR72_RS11675	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS11680	COG1309	transcriptional regulator
CBR72_RS11715	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBR72_RS11720	COG4654	Cytochrome c, class I
CBR72_RS11725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR72_RS11775	COG1473	amidohydrolase
CBR72_RS11780	COG0418	dihydroorotase activity
CBR72_RS11785	COG0488	(ABC) transporter
CBR72_RS11795	COG2001	Belongs to the MraZ family
CBR72_RS11800	COG0275	rRNA processing
CBR72_RS11805	COG3116	cell division
CBR72_RS11815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR72_RS11820	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR72_RS11825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBR72_RS11835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBR72_RS11840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR72_RS11845	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBR72_RS11850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBR72_RS11865	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBR72_RS11880	COG0739	heme binding
CBR72_RS11885	COG0653	protein targeting
CBR72_RS11910	COG1522	sequence-specific DNA binding
CBR72_RS11925	COG2239	Acts as a magnesium transporter
CBR72_RS11935	COG2855	membrane
CBR72_RS11940	COG0583	DNA-binding transcription factor activity
CBR72_RS11945	COG1473	amidohydrolase
CBR72_RS11950	COG0318	PFAM AMP-dependent synthetase and ligase
CBR72_RS11960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CBR72_RS11960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR72_RS11965	COG1501	Belongs to the glycosyl hydrolase 31 family
CBR72_RS11970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBR72_RS11975	COG2011	ABC-type metal ion transport system permease component
CBR72_RS11995	COG1368	sulfuric ester hydrolase activity
CBR72_RS12005	COG1596	polysaccharide export
CBR72_RS12045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBR72_RS12050	COG1051	belongs to the nudix hydrolase family
CBR72_RS12075	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CBR72_RS12080	COG0156	8-amino-7-oxononanoate synthase activity
CBR72_RS12085	COG0604	alcohol dehydrogenase
CBR72_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS12085	COG3321	synthase
CBR72_RS12090	COG0402	S-adenosylhomocysteine deaminase activity
CBR72_RS12115	COG0727	PFAM Uncharacterised protein family (UPF0153)
CBR72_RS12120	COG2818	Glycosylase
CBR72_RS12125	COG2982	Protein involved in outer membrane biogenesis
CBR72_RS12165	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS12180	COG0410	ABC transporter
CBR72_RS12200	COG0583	DNA-binding transcription factor activity
CBR72_RS12205	COG0737	Belongs to the 5'-nucleotidase family
CBR72_RS12215	COG4106	trans-aconitate 2-methyltransferase activity
CBR72_RS12220	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR72_RS12230	COG0667	Aldo Keto reductase
CBR72_RS12245	COG2154	pterin-4-alpha-carbinolamine dehydratase
CBR72_RS12255	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CBR72_RS12265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CBR72_RS12270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR72_RS12275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBR72_RS12285	COG1929	Belongs to the glycerate kinase type-1 family
CBR72_RS12290	COG0469	pyruvate kinase activity
CBR72_RS12295	COG0700	Nucleoside recognition
CBR72_RS12300	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS12305	COG0242	peptide deformylase activity
CBR72_RS12325	COG1053	succinate dehydrogenase
CBR72_RS12325	COG3976	FMN-binding domain protein
CBR72_RS12330	COG0583	DNA-binding transcription factor activity
CBR72_RS12340	COG0204	Acyl-transferase
CBR72_RS12345	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR72_RS12350	COG0751	glycine-tRNA ligase activity
CBR72_RS12355	COG0752	glycyl-tRNA synthetase alpha subunit
CBR72_RS12360	COG1024	Enoyl-CoA hydratase
CBR72_RS12370	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CBR72_RS12400	COG0617	tRNA 3'-terminal CCA addition
CBR72_RS12415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBR72_RS12420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBR72_RS12425	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBR72_RS12430	COG0586	Pfam SNARE associated Golgi protein
CBR72_RS12435	COG3064	Membrane
CBR72_RS12435	COG3210	domain, Protein
CBR72_RS12435	COG3064	Membrane
CBR72_RS12435	COG3210	domain, Protein
CBR72_RS12435	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS12435	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS12440	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBR72_RS12450	COG0114	fumarate hydratase activity
CBR72_RS12460	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS12470	COG0405	Gamma-glutamyltransferase
CBR72_RS12480	COG3210	domain, Protein
CBR72_RS12490	COG0579	oxidoreductase
CBR72_RS12495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR72_RS12500	COG0259	pyridoxamine-phosphate oxidase activity
CBR72_RS12515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS12520	COG0577	efflux transmembrane transporter activity
CBR72_RS12520	COG1136	(ABC) transporter
CBR72_RS12525	COG1538	Outer membrane efflux protein
CBR72_RS12530	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBR72_RS12540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR72_RS12565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBR72_RS12590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS12655	COG0583	DNA-binding transcription factor activity
CBR72_RS12680	COG0427	acetyl-CoA hydrolase
CBR72_RS12685	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS12690	COG2301	Belongs to the HpcH HpaI aldolase family
CBR72_RS12720	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS12725	COG0683	leucine binding
CBR72_RS12735	COG2205	protein histidine kinase activity
CBR72_RS12740	COG3210	domain, Protein
CBR72_RS12750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS12755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR72_RS12760	COG1538	Outer membrane efflux protein
CBR72_RS12780	COG3258	Cytochrome c
CBR72_RS12785	COG2863	cytochrome
CBR72_RS12805	COG2205	protein histidine kinase activity
CBR72_RS12820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS12825	COG2301	Belongs to the HpcH HpaI aldolase family
CBR72_RS12840	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS12850	COG2814	Major facilitator Superfamily
CBR72_RS12865	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS12870	COG4948	Mandelate Racemase Muconate Lactonizing
CBR72_RS12875	COG0583	DNA-binding transcription factor activity
CBR72_RS12925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR72_RS12935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR72_RS12940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR72_RS12955	COG2188	Transcriptional regulator
CBR72_RS12960	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR72_RS12970	COG0402	S-adenosylhomocysteine deaminase activity
CBR72_RS12975	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBR72_RS12980	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR72_RS12980	COG0022	dehydrogenase e1 component
CBR72_RS12985	COG1024	Enoyl-CoA hydratase
CBR72_RS12990	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR72_RS13000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR72_RS13030	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS13035	COG0411	ABC transporter
CBR72_RS13060	COG1309	transcriptional regulator
CBR72_RS13075	COG1024	Enoyl-CoA hydratase
CBR72_RS13095	COG4133	protoheme IX ABC transporter activity
CBR72_RS13100	COG0154	amidase activity
CBR72_RS13110	COG0583	DNA-binding transcription factor activity
CBR72_RS13125	COG2197	response regulator
CBR72_RS13130	COG2814	Major facilitator Superfamily
CBR72_RS13140	COG4774	siderophore transport
CBR72_RS13145	COG3712	iron ion homeostasis
CBR72_RS13150	COG1595	DNA-templated transcription, initiation
CBR72_RS13195	COG0625	glutathione transferase activity
CBR72_RS13205	COG0747	negative chemotaxis
CBR72_RS13210	COG0583	DNA-binding transcription factor activity
CBR72_RS13245	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS13250	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS13255	COG2207	Transcriptional regulator
CBR72_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS13275	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS13280	COG3284	Transcriptional regulator
CBR72_RS13290	COG2814	Major facilitator Superfamily
CBR72_RS13295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS13305	COG1959	2 iron, 2 sulfur cluster binding
CBR72_RS13315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR72_RS13320	COG1971	Probably functions as a manganese efflux pump
CBR72_RS13335	COG1360	Flagellar Motor Protein
CBR72_RS13350	COG0840	transmembrane signaling receptor activity
CBR72_RS13370	COG5265	(ABC) transporter
CBR72_RS13385	COG0833	amino acid
CBR72_RS13415	COG0235	Class ii aldolase
CBR72_RS13425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR72_RS13430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS13435	COG2186	Transcriptional regulator
CBR72_RS13440	COG1024	Enoyl-CoA hydratase
CBR72_RS13455	COG0583	DNA-binding transcription factor activity
CBR72_RS13465	COG2159	amidohydrolase
CBR72_RS13480	COG1301	dicarboxylic acid transport
CBR72_RS13490	COG0148	phosphopyruvate hydratase activity
CBR72_RS13500	COG2814	Major facilitator Superfamily
CBR72_RS13505	COG0583	DNA-binding transcription factor activity
CBR72_RS13555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR72_RS13565	COG4774	siderophore transport
CBR72_RS13575	COG3128	pkhd-type hydroxylase
CBR72_RS13595	COG1408	metallophosphoesterase
CBR72_RS13605	COG0456	acetyltransferase
CBR72_RS13615	COG2610	gluconate transmembrane transporter activity
CBR72_RS13625	COG2070	2-Nitropropane dioxygenase
CBR72_RS13635	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CBR72_RS13680	COG1846	Transcriptional regulator
CBR72_RS13695	COG3300	MHYT domain
CBR72_RS13695	COG5001	Diguanylate cyclase
CBR72_RS13725	COG4964	Belongs to the GSP D family
CBR72_RS13775	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS13780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBR72_RS13795	COG3384	dioxygenase
CBR72_RS13800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR72_RS13820	COG2176	DNA-directed DNA polymerase activity
CBR72_RS13845	COG4221	oxidoreductase activity
CBR72_RS13855	COG3264	Mechanosensitive ion channel
CBR72_RS13855	COG1511	domain protein
CBR72_RS13860	COG0583	DNA-binding transcription factor activity
CBR72_RS13865	COG0427	acetyl-CoA hydrolase
CBR72_RS13870	COG0583	DNA-binding transcription factor activity
CBR72_RS13930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS13945	COG0154	amidase activity
CBR72_RS13960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBR72_RS13975	COG0495	leucyl-tRNA aminoacylation
CBR72_RS13980	COG2814	Major facilitator Superfamily
CBR72_RS13985	COG1846	Transcriptional regulator
CBR72_RS14005	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBR72_RS14010	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBR72_RS14015	COG2814	Major facilitator Superfamily
CBR72_RS14020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBR72_RS14030	COG4176	ABC-type proline glycine betaine transport system permease component
CBR72_RS14045	COG0183	Belongs to the thiolase family
CBR72_RS14065	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR72_RS14065	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR72_RS14075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR72_RS14080	COG1845	cytochrome c oxidase, subunit III
CBR72_RS14085	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR72_RS14090	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CBR72_RS14095	COG0477	Major facilitator Superfamily
CBR72_RS14100	COG0428	transporter
CBR72_RS14105	COG0412	Dienelactone hydrolase
CBR72_RS14110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR72_RS14115	COG1283	sodium-dependent phosphate transmembrane transporter activity
CBR72_RS14120	COG1760	l-serine dehydratase
CBR72_RS14125	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBR72_RS14130	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CBR72_RS14140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBR72_RS14165	COG2311	Membrane
CBR72_RS14175	COG2358	TRAP transporter, solute receptor (TAXI family
CBR72_RS14180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS14195	COG0456	acetyltransferase
CBR72_RS14205	COG0662	Cupin 2, conserved barrel domain protein
CBR72_RS14210	COG5285	phytanoyl-CoA dioxygenase
CBR72_RS14215	COG3217	Mosc domain protein beta barrel domain protein
CBR72_RS14215	COG0633	Ferredoxin
CBR72_RS14220	COG2076	Multidrug Resistance protein
CBR72_RS14225	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBR72_RS14230	COG0543	2 iron, 2 sulfur cluster binding
CBR72_RS14230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR72_RS14235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR72_RS14285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR72_RS14290	COG0425	Belongs to the sulfur carrier protein TusA family
CBR72_RS14300	COG0228	four-way junction DNA binding
CBR72_RS14305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBR72_RS14310	COG0336	Belongs to the RNA methyltransferase TrmD family
CBR72_RS14315	COG0525	valine-tRNA ligase activity
CBR72_RS14320	COG0105	UTP biosynthetic process
CBR72_RS14325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR72_RS14340	COG0124	histidyl-tRNA synthetase
CBR72_RS14345	COG2976	Protein conserved in bacteria
CBR72_RS14350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR72_RS14355	COG1160	GTP binding
CBR72_RS14360	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR72_RS14365	COG1923	regulation of RNA biosynthetic process
CBR72_RS14370	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBR72_RS14375	COG0330	HflC and HflK could
CBR72_RS14380	COG0330	HflC and HflK could
CBR72_RS14385	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBR72_RS14390	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBR72_RS14400	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBR72_RS14450	COG2207	Transcriptional regulator
CBR72_RS14480	COG0330	HflC and HflK could
CBR72_RS14495	COG0840	transmembrane signaling receptor activity
CBR72_RS14530	COG2201	protein-glutamate methylesterase activity
CBR72_RS14535	COG3706	GGDEF domain
CBR72_RS14535	COG4251	negative regulation of phosphorylation
CBR72_RS14535	COG5001	Diguanylate cyclase
CBR72_RS14535	COG2203	Gaf domain
CBR72_RS14540	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CBR72_RS14575	COG0583	DNA-binding transcription factor activity
CBR72_RS14590	COG2084	Dehydrogenase
CBR72_RS14600	COG1597	lipid kinase activity
CBR72_RS14600	COG1803	Methylglyoxal synthase
CBR72_RS14610	COG0671	phosphoesterase, PA-phosphatase related
CBR72_RS14630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS14635	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR72_RS14640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR72_RS14645	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR72_RS14650	COG0649	NAD binding
CBR72_RS14655	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CBR72_RS14665	COG1034	ATP synthesis coupled electron transport
CBR72_RS14670	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBR72_RS14675	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR72_RS14685	COG0713	ATP synthesis coupled electron transport
CBR72_RS14700	COG1007	ATP synthesis coupled electron transport
CBR72_RS14710	COG0560	Phosphoserine phosphatase
CBR72_RS14715	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBR72_RS14720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBR72_RS14725	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBR72_RS14730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR72_RS14735	COG0450	alkyl hydroperoxide reductase
CBR72_RS14750	COG1214	PFAM Peptidase M22, glycoprotease
CBR72_RS14755	COG1573	uracil-dna glycosylase
CBR72_RS14760	COG0477	Major facilitator Superfamily
CBR72_RS14765	COG1196	nuclear chromosome segregation
CBR72_RS14775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBR72_RS14785	COG0765	amino acid transport
CBR72_RS14790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS14800	COG0625	glutathione transferase activity
CBR72_RS14805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR72_RS14810	COG0271	Belongs to the BolA IbaG family
CBR72_RS14815	COG2917	probably involved in intracellular septation
CBR72_RS14820	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR72_RS14825	COG1122	ATPase activity
CBR72_RS14830	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBR72_RS14835	COG1268	BioY protein
CBR72_RS14865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS14895	COG0411	ABC transporter
CBR72_RS14900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBR72_RS14905	COG2878	Part of a membrane complex involved in electron transport
CBR72_RS14930	COG0251	oxidation-reduction process
CBR72_RS14940	COG3228	Belongs to the MtfA family
CBR72_RS14945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR72_RS14965	COG0159	tryptophan synthase activity
CBR72_RS14970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBR72_RS14975	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CBR72_RS14980	COG1530	ribonuclease E activity
CBR72_RS14985	COG0564	pseudouridine synthase activity
CBR72_RS14990	COG0546	phosphoglycolate phosphatase activity
CBR72_RS14995	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CBR72_RS15000	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBR72_RS15005	COG3023	N-Acetylmuramoyl-L-alanine amidase
CBR72_RS15015	COG0424	maF-like protein
CBR72_RS15020	COG1399	metal-binding, possibly nucleic acid-binding protein
CBR72_RS15025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBR72_RS15035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR72_RS15045	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS15050	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBR72_RS15055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBR72_RS15080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR72_RS15085	COG0481	GTPase activity
CBR72_RS15090	COG0681	Belongs to the peptidase S26 family
CBR72_RS15095	COG0571	ribonuclease III activity
CBR72_RS15100	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBR72_RS15105	COG1381	Involved in DNA repair and RecF pathway recombination
CBR72_RS15125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBR72_RS15135	COG0583	DNA-binding transcription factor activity
CBR72_RS15150	COG0583	DNA-binding transcription factor activity
CBR72_RS15160	COG0791	NLP P60 protein
CBR72_RS15165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR72_RS15170	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CBR72_RS15180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR72_RS15185	COG0697	spore germination
CBR72_RS15190	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CBR72_RS15230	COG1446	asparaginase
CBR72_RS15235	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS15240	COG0747	negative chemotaxis
CBR72_RS15245	COG0601	transmembrane transport
CBR72_RS15250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS15270	COG0504	CTP synthase activity
CBR72_RS15280	COG0148	phosphopyruvate hydratase activity
CBR72_RS15295	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CBR72_RS15305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR72_RS15310	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR72_RS15330	COG1981	membrane
CBR72_RS15350	COG0039	L-malate dehydrogenase activity
CBR72_RS15355	COG2188	Transcriptional regulator
CBR72_RS15360	COG2009	succinate dehydrogenase
CBR72_RS15365	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CBR72_RS15370	COG1053	succinate dehydrogenase
CBR72_RS15375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBR72_RS15380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CBR72_RS15385	COG0372	Belongs to the citrate synthase family
CBR72_RS15390	COG0583	DNA-binding transcription factor activity
CBR72_RS15395	COG3842	ATPase activity
CBR72_RS15405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR72_RS15410	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR72_RS15435	COG3128	pkhd-type hydroxylase
CBR72_RS15440	COG4774	siderophore transport
CBR72_RS15445	COG0281	malic enzyme
CBR72_RS15445	COG0280	phosphate acetyltransferase
CBR72_RS15455	COG1297	OPT oligopeptide transporter protein
CBR72_RS15460	COG0567	Dehydrogenase, E1 component
CBR72_RS15465	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR72_RS15470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR72_RS15475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CBR72_RS15500	COG2183	response to ionizing radiation
CBR72_RS15505	COG1199	ATP-dependent helicase activity
CBR72_RS15555	COG0564	pseudouridine synthase activity
CBR72_RS15565	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR72_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS15575	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CBR72_RS15590	COG0672	)-iron permease
CBR72_RS15605	COG2823	Periplasmic or secreted lipoprotein
CBR72_RS15615	COG3237	CsbD-like
CBR72_RS15620	COG3038	cytochrome b561
CBR72_RS15625	COG0189	ligase activity
CBR72_RS15625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR72_RS15630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR72_RS15630	COG0189	ligase activity
CBR72_RS15635	COG1132	(ABC) transporter
CBR72_RS15645	COG0297	glycogen (starch) synthase activity
CBR72_RS15650	COG2833	Protein of unknown function (DUF455)
CBR72_RS15655	COG2951	lytic endotransglycosylase activity
CBR72_RS15665	COG0589	response to stress
CBR72_RS15675	COG3706	GGDEF domain
CBR72_RS15740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBR72_RS15755	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBR72_RS15760	COG1605	Chorismate mutase
CBR72_RS15760	COG0077	Prephenate dehydratase
CBR72_RS15765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR72_RS15770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR72_RS15775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBR72_RS15780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CBR72_RS15800	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CBR72_RS15805	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CBR72_RS15810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBR72_RS15815	COG0587	DNA-directed DNA polymerase activity
CBR72_RS15825	COG2951	lytic endotransglycosylase activity
CBR72_RS15830	COG0123	including yeast histone deacetylase and acetoin utilization protein
CBR72_RS15845	COG2985	domain, Protein
CBR72_RS15850	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS15855	COG0450	alkyl hydroperoxide reductase
CBR72_RS15860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBR72_RS15865	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CBR72_RS15870	COG4208	sulfate ABC transporter
CBR72_RS15875	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR72_RS15880	COG0175	sulfate reduction
CBR72_RS15890	COG2895	sulfate adenylyltransferase (ATP) activity
CBR72_RS15910	COG0335	large ribosomal subunit rRNA binding
CBR72_RS15915	COG0494	nUDIX hydrolase
CBR72_RS15920	COG3622	Belongs to the hyi family
CBR72_RS15925	COG1162	GTPase activity
CBR72_RS15930	COG0501	Belongs to the peptidase M48B family
CBR72_RS15935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CBR72_RS15940	COG1335	isochorismatase
CBR72_RS15950	COG0583	DNA-binding transcription factor activity
CBR72_RS15965	COG3396	Phenylacetate-CoA oxygenase
CBR72_RS15970	COG3460	Phenylacetate-CoA oxygenase
CBR72_RS15975	COG3396	Phenylacetate-CoA oxygenase
CBR72_RS15980	COG2151	metal-sulfur cluster biosynthetic enzyme
CBR72_RS15985	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR72_RS15990	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS15995	COG1024	Enoyl-CoA hydratase
CBR72_RS16000	COG2050	protein possibly involved in aromatic compounds catabolism
CBR72_RS16020	COG1126	abc transporter atp-binding protein
CBR72_RS16045	COG0784	Response regulator, receiver
CBR72_RS16045	COG5002	protein histidine kinase activity
CBR72_RS16045	COG2198	Histidine kinase
CBR72_RS16050	COG3437	response regulator, receiver
CBR72_RS16065	COG1802	Transcriptional regulator
CBR72_RS16070	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR72_RS16070	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR72_RS16080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS16085	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CBR72_RS16095	COG3642	lipopolysaccharide core region biosynthetic process
CBR72_RS16105	COG3842	ATPase activity
CBR72_RS16110	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR72_RS16115	COG1177	transmembrane transport
CBR72_RS16120	COG1393	Belongs to the ArsC family
CBR72_RS16125	COG2094	Belongs to the DNA glycosylase MPG family
CBR72_RS16135	COG1322	Protein conserved in bacteria
CBR72_RS16140	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS16145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBR72_RS16150	COG0704	Plays a role in the regulation of phosphate uptake
CBR72_RS16155	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CBR72_RS16160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR72_RS16160	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CBR72_RS16165	COG1643	Atp-dependent helicase
CBR72_RS16180	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS16185	COG0726	polysaccharide deacetylase
CBR72_RS16225	COG1132	(ABC) transporter
CBR72_RS16230	COG3468	outer membrane autotransporter barrel domain protein
CBR72_RS16240	COG1530	ribonuclease E activity
CBR72_RS16270	COG0583	DNA-binding transcription factor activity
CBR72_RS16280	COG0477	Major facilitator Superfamily
CBR72_RS16285	COG0500	methyltransferase
CBR72_RS16290	COG1418	mRNA catabolic process
CBR72_RS16315	COG2204	response regulator
CBR72_RS16320	COG4191	Histidine kinase
CBR72_RS16325	COG1301	dicarboxylic acid transport
CBR72_RS16330	COG0424	maF-like protein
CBR72_RS16335	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBR72_RS16340	COG0799	negative regulation of ribosome biogenesis
CBR72_RS16345	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBR72_RS16355	COG0151	Belongs to the GarS family
CBR72_RS16360	COG0217	transcriptional regulatory protein
CBR72_RS16365	COG0433	COG0433 Predicted ATPase
CBR72_RS16370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS16375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR72_RS16380	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS16405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR72_RS16410	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS16415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS16420	COG0601	transmembrane transport
CBR72_RS16425	COG0747	negative chemotaxis
CBR72_RS16435	COG0473	3-isopropylmalate dehydrogenase activity
CBR72_RS16440	COG2814	Major facilitator Superfamily
CBR72_RS16445	COG1566	PFAM secretion protein HlyD family protein
CBR72_RS16455	COG1846	Transcriptional regulator
CBR72_RS16475	COG0501	Belongs to the peptidase M48B family
CBR72_RS16515	COG1722	exodeoxyribonuclease VII activity
CBR72_RS16520	COG0142	geranyltranstransferase activity
CBR72_RS16525	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBR72_RS16530	COG1469	GTP cyclohydrolase I activity
CBR72_RS16535	COG0360	Binds together with S18 to 16S ribosomal RNA
CBR72_RS16540	COG2965	DNA replication, synthesis of RNA primer
CBR72_RS16545	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBR72_RS16550	COG0359	binds to the 23S rRNA
CBR72_RS16560	COG0305	Participates in initiation and elongation during chromosome replication
CBR72_RS16570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CBR72_RS16575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CBR72_RS16580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBR72_RS16585	COG3737	Protein of unknown function (DUF498/DUF598)
CBR72_RS16590	COG0436	Aminotransferase
CBR72_RS16610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CBR72_RS16615	COG0308	aminopeptidase N
CBR72_RS16630	COG0312	modulator of DNA gyrase
CBR72_RS16635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR72_RS16640	COG0277	FAD linked oxidase domain protein
CBR72_RS16645	COG0277	FAD linked oxidase domain protein
CBR72_RS16650	COG0277	FAD linked oxidase domain protein
CBR72_RS16655	COG0247	lactate metabolic process
CBR72_RS16680	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS16685	COG0583	DNA-binding transcription factor activity
CBR72_RS16690	COG0482	sulfurtransferase activity
CBR72_RS16695	COG0730	response to heat
CBR72_RS16700	COG0625	glutathione transferase activity
CBR72_RS16710	COG3909	cytochrome
CBR72_RS16740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR72_RS16750	COG3706	GGDEF domain
CBR72_RS16775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBR72_RS16780	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CBR72_RS16790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR72_RS16795	COG0069	glutamate synthase activity
CBR72_RS16800	COG2391	methyltransferase activity
CBR72_RS16805	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CBR72_RS16810	COG0679	Auxin Efflux Carrier
CBR72_RS16840	COG0557	exoribonuclease II activity
CBR72_RS16845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR72_RS16855	COG0776	regulation of translation
CBR72_RS16885	COG0642	Histidine kinase
CBR72_RS16890	COG3158	transport of potassium into the cell
CBR72_RS16905	COG0137	argininosuccinate synthase activity
CBR72_RS16910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBR72_RS16915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR72_RS16925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR72_RS16940	COG2186	Transcriptional regulator
CBR72_RS16960	COG3836	Belongs to the HpcH HpaI aldolase family
CBR72_RS16965	COG0268	Binds directly to 16S ribosomal RNA
CBR72_RS16990	COG0728	peptidoglycan biosynthetic process
CBR72_RS17000	COG0563	adenylate kinase activity
CBR72_RS17005	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBR72_RS17010	COG2835	tetraacyldisaccharide 4'-kinase activity
CBR72_RS17015	COG1663	tetraacyldisaccharide 4'-kinase activity
CBR72_RS17025	COG0811	peptide transport
CBR72_RS17030	COG1570	exodeoxyribonuclease VII activity
CBR72_RS17035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBR72_RS17040	COG0038	chloride channel
CBR72_RS17045	COG0183	Belongs to the thiolase family
CBR72_RS17055	COG1278	Cold shock
CBR72_RS17060	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBR72_RS17070	COG4953	penicillin-binding protein 1C
CBR72_RS17075	COG0542	response to heat
CBR72_RS17080	COG2995	paraquat-inducible protein a
CBR72_RS17085	COG3008	intermembrane lipid transfer
CBR72_RS17095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR72_RS17095	COG0506	proline dehydrogenase activity
CBR72_RS17095	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR72_RS17125	COG2271	Major facilitator Superfamily
CBR72_RS17135	COG0004	ammonium transporteR
CBR72_RS17140	COG0347	Belongs to the P(II) protein family
CBR72_RS17160	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBR72_RS17165	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBR72_RS17170	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBR72_RS17175	COG0072	phenylalanine-tRNA ligase activity
CBR72_RS17175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR72_RS17180	COG0776	regulation of translation
CBR72_RS17210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CBR72_RS17235	COG1522	sequence-specific DNA binding
CBR72_RS17285	COG5265	(ABC) transporter
CBR72_RS17290	COG0656	L-ascorbic acid biosynthetic process
CBR72_RS17295	COG0667	Aldo Keto reductase
CBR72_RS17310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR72_RS17335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBR72_RS17355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR72_RS17360	COG3246	L-lysine catabolic process to acetate
CBR72_RS17365	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS17370	COG0583	DNA-binding transcription factor activity
CBR72_RS17380	COG0129	dihydroxy-acid dehydratase activity
CBR72_RS17385	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS17430	COG0154	amidase activity
CBR72_RS17435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS17465	COG2267	carboxylic ester hydrolase activity
CBR72_RS17470	COG0501	Belongs to the peptidase M48B family
CBR72_RS17480	COG0789	Transcriptional regulator
CBR72_RS17485	COG0778	Nitroreductase
CBR72_RS17490	COG0165	Argininosuccinate lyase
CBR72_RS17495	COG0668	transmembrane transport
CBR72_RS17500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR72_RS17500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CBR72_RS17515	COG0583	DNA-binding transcription factor activity
CBR72_RS17525	COG0747	negative chemotaxis
CBR72_RS17530	COG0601	transmembrane transport
CBR72_RS17535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS17540	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS17550	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS17560	COG3161	chorismate lyase activity
CBR72_RS17565	COG1187	pseudouridine synthase activity
CBR72_RS17575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS17600	COG1999	signal sequence binding
CBR72_RS17610	COG0339	signal peptide processing
CBR72_RS17615	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBR72_RS17620	COG4566	intracellular signal transduction
CBR72_RS17630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CBR72_RS17635	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR72_RS17640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR72_RS17680	COG0745	RESPONSE REGULATOR receiver
CBR72_RS17695	COG0840	transmembrane signaling receptor activity
CBR72_RS17700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CBR72_RS17705	COG2201	protein-glutamate methylesterase activity
CBR72_RS17710	COG0745	RESPONSE REGULATOR receiver
CBR72_RS17715	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CBR72_RS17720	COG0840	transmembrane signaling receptor activity
CBR72_RS17745	COG2747	anti-sigma28 factor FlgM
CBR72_RS17770	COG1749	Flagellar hook protein flgE
CBR72_RS17790	COG1706	bacterial-type flagellum-dependent cell motility
CBR72_RS17800	COG1256	bacterial-type flagellum assembly
CBR72_RS17810	COG0840	transmembrane signaling receptor activity
CBR72_RS17815	COG0840	transmembrane signaling receptor activity
CBR72_RS17825	COG0840	transmembrane signaling receptor activity
CBR72_RS17830	COG0840	transmembrane signaling receptor activity
CBR72_RS17855	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR72_RS17865	COG1580	Controls the rotational direction of flagella during chemotaxis
CBR72_RS17875	COG2882	bacterial-type flagellum organization
CBR72_RS17885	COG1317	bacterial-type flagellum organization
CBR72_RS17890	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR72_RS17895	COG1766	The M ring may be actively involved in energy transduction
CBR72_RS17900	COG1677	Flagellar hook-basal body complex protein FliE
CBR72_RS17910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBR72_RS17930	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CBR72_RS17950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS17955	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS17965	COG0285	dihydrofolate synthase activity
CBR72_RS17975	COG1286	toxin biosynthetic process
CBR72_RS17995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CBR72_RS18000	COG0024	Methionine aminopeptidase
CBR72_RS18005	COG0052	Belongs to the universal ribosomal protein uS2 family
CBR72_RS18010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBR72_RS18015	COG0528	UMP kinase activity
CBR72_RS18020	COG0233	cytoplasmic translational termination
CBR72_RS18025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBR72_RS18030	COG0575	Belongs to the CDS family
CBR72_RS18035	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBR72_RS18040	COG0750	zinc metalloprotease
CBR72_RS18045	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR72_RS18055	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR72_RS18060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBR72_RS18070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR72_RS18075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBR72_RS18080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR72_RS18090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBR72_RS18115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBR72_RS18125	COG2914	Belongs to the UPF0125 (RnfH) family
CBR72_RS18130	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS18135	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS18135	COG1024	Enoyl-CoA hydratase
CBR72_RS18155	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBR72_RS18160	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBR72_RS18170	COG0084	hydrolase, TatD family'
CBR72_RS18185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS18190	COG0765	amino acid transport
CBR72_RS18195	COG1126	abc transporter atp-binding protein
CBR72_RS18200	COG0010	Belongs to the arginase family
CBR72_RS18220	COG4221	oxidoreductase activity
CBR72_RS18225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR72_RS18235	COG2059	Chromate
CBR72_RS18240	COG0640	Transcriptional regulator
CBR72_RS18250	COG0740	serine-type endopeptidase activity
CBR72_RS18260	COG0095	Lipoate-protein ligase
CBR72_RS18285	COG0386	Belongs to the glutathione peroxidase family
CBR72_RS18310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS18355	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR72_RS18360	COG2259	Doxx family
CBR72_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS18390	COG0842	Transport permease protein
CBR72_RS18395	COG0842	Transport permease protein
CBR72_RS18395	COG1129	ABC transporter
CBR72_RS18400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR72_RS18410	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR72_RS18430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CBR72_RS18455	COG2733	membrane
CBR72_RS18465	COG3042	response to heat
CBR72_RS18470	COG3258	Cytochrome c
CBR72_RS18500	COG3958	Transketolase
CBR72_RS18505	COG3959	Transketolase, thiamine diphosphate binding domain
CBR72_RS18525	COG0583	DNA-binding transcription factor activity
CBR72_RS18530	COG0028	Belongs to the TPP enzyme family
CBR72_RS18535	COG0477	Major facilitator Superfamily
CBR72_RS18540	COG0583	DNA-binding transcription factor activity
CBR72_RS18545	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS18550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS18560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR72_RS18580	COG0519	Catalyzes the synthesis of GMP from XMP
CBR72_RS18580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR72_RS18595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS18610	COG1024	Enoyl-CoA hydratase
CBR72_RS18625	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS18630	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS18675	COG1122	ATPase activity
CBR72_RS18690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR72_RS18695	COG2900	Belongs to the SlyX family
CBR72_RS18710	COG0456	acetyltransferase
CBR72_RS18715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR72_RS18750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR72_RS18785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS18835	COG0066	3-isopropylmalate dehydratase activity
CBR72_RS18840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBR72_RS18845	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS18850	COG4948	Mandelate Racemase Muconate Lactonizing
CBR72_RS18855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR72_RS18860	COG3842	ATPase activity
CBR72_RS18865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR72_RS18875	COG3833	ABC-type maltose transport systems, permease component
CBR72_RS18880	COG1175	transmembrane transport
CBR72_RS18885	COG2182	Extracellular solute-binding protein
CBR72_RS18895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS18900	COG0765	amino acid transport
CBR72_RS18905	COG0765	amino acid transport
CBR72_RS18920	COG3665	Urea carboxylase-associated protein
CBR72_RS18940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR72_RS18965	COG1937	Protein conserved in bacteria
CBR72_RS18985	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS19010	COG2863	cytochrome
CBR72_RS19015	COG3568	Endonuclease Exonuclease Phosphatase
CBR72_RS19020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR72_RS19025	COG0392	lysyltransferase activity
CBR72_RS19030	COG0166	Belongs to the GPI family
CBR72_RS19045	COG1546	Belongs to the CinA family
CBR72_RS19045	COG1058	Belongs to the CinA family
CBR72_RS19055	COG0668	transmembrane transport
CBR72_RS19060	COG0297	glycogen (starch) synthase activity
CBR72_RS19070	COG0366	Alpha amylase catalytic
CBR72_RS19075	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR72_RS19085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR72_RS19090	COG1640	4-alpha-glucanotransferase
CBR72_RS19120	COG3685	Protein conserved in bacteria
CBR72_RS19125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBR72_RS19130	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS19140	COG1216	Glycosyl transferase, family 2
CBR72_RS19175	COG2192	nodulation
CBR72_RS19185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR72_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS19200	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS19215	COG5265	(ABC) transporter
CBR72_RS19235	COG0028	Belongs to the TPP enzyme family
CBR72_RS19240	COG2204	response regulator
CBR72_RS19245	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR72_RS19250	COG0583	DNA-binding transcription factor activity
CBR72_RS19255	COG0477	Major facilitator Superfamily
CBR72_RS19260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR72_RS19280	COG1137	ATPase activity
CBR72_RS19305	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS19310	COG1129	ABC transporter
CBR72_RS19350	COG0402	S-adenosylhomocysteine deaminase activity
CBR72_RS19355	COG0747	negative chemotaxis
CBR72_RS19360	COG0601	transmembrane transport
CBR72_RS19365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR72_RS19370	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS19375	COG1063	alcohol dehydrogenase
CBR72_RS19400	COG2175	clavaminate synthase activity
CBR72_RS19405	COG1454	alcohol dehydrogenase
CBR72_RS19410	COG0583	DNA-binding transcription factor activity
CBR72_RS19420	COG1024	Enoyl-CoA hydratase
CBR72_RS19425	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS19430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS19440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR72_RS19450	COG1024	Enoyl-CoA hydratase
CBR72_RS19450	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR72_RS19455	COG0183	Belongs to the thiolase family
CBR72_RS19460	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS19465	COG0318	PFAM AMP-dependent synthetase and ligase
CBR72_RS19470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR72_RS19485	COG0154	amidase activity
CBR72_RS19490	COG2271	Major facilitator Superfamily
CBR72_RS19500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR72_RS19530	COG0318	PFAM AMP-dependent synthetase and ligase
CBR72_RS19540	COG2267	carboxylic ester hydrolase activity
CBR72_RS19550	COG1024	Enoyl-CoA hydratase
CBR72_RS19560	COG0431	NADPH-dependent FMN reductase
CBR72_RS19600	COG2819	hydrolase of the alpha beta superfamily
CBR72_RS19615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR72_RS19625	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR72_RS19655	COG1126	abc transporter atp-binding protein
CBR72_RS19660	COG0765	amino acid transport
CBR72_RS19665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS19690	COG0410	ABC transporter
CBR72_RS19710	COG2200	EAL domain
CBR72_RS19720	COG1595	DNA-templated transcription, initiation
CBR72_RS19735	COG1253	flavin adenine dinucleotide binding
CBR72_RS19745	COG2203	Gaf domain
CBR72_RS19745	COG3706	GGDEF domain
CBR72_RS19745	COG4251	negative regulation of phosphorylation
CBR72_RS19745	COG5001	Diguanylate cyclase
CBR72_RS19750	COG2197	response regulator
CBR72_RS19755	COG2205	protein histidine kinase activity
CBR72_RS19755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS19760	COG2814	Major facilitator Superfamily
CBR72_RS19765	COG0076	glutamate decarboxylase activity
CBR72_RS19770	COG2985	domain, Protein
CBR72_RS19775	COG3189	MarR family transcriptional regulator
CBR72_RS19780	COG2186	Transcriptional regulator
CBR72_RS19785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS19795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR72_RS19795	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR72_RS19805	COG0028	Belongs to the TPP enzyme family
CBR72_RS19815	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS19825	COG0688	phosphatidylethanolamine metabolic process
CBR72_RS19835	COG1464	Belongs to the NlpA lipoprotein family
CBR72_RS19855	COG2363	Small membrane protein
CBR72_RS19860	COG0697	spore germination
CBR72_RS19870	COG2133	pyrroloquinoline quinone binding
CBR72_RS19875	COG0625	glutathione transferase activity
CBR72_RS19885	COG1794	racemase activity, acting on amino acids and derivatives
CBR72_RS19905	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR72_RS19915	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CBR72_RS19930	COG1175	transmembrane transport
CBR72_RS19935	COG0395	ABC-type sugar transport system, permease component
CBR72_RS19940	COG3842	ATPase activity
CBR72_RS19955	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR72_RS19970	COG0438	transferase activity, transferring glycosyl groups
CBR72_RS19990	COG1216	Glycosyl transferase, family 2
CBR72_RS20005	COG0783	Belongs to the Dps family
CBR72_RS20015	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CBR72_RS20030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR72_RS20075	COG0583	DNA-binding transcription factor activity
CBR72_RS20080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBR72_RS20100	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR72_RS20110	COG3842	ATPase activity
CBR72_RS20115	COG1741	Belongs to the pirin family
CBR72_RS20120	COG1741	Belongs to the pirin family
CBR72_RS20125	COG0583	DNA-binding transcription factor activity
CBR72_RS20140	COG5002	protein histidine kinase activity
CBR72_RS20140	COG0784	Response regulator, receiver
CBR72_RS20140	COG2205	protein histidine kinase activity
CBR72_RS20155	COG3852	Histidine kinase
CBR72_RS20160	COG0174	glutamine synthetase
CBR72_RS20165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR72_RS20170	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBR72_RS20175	COG3300	MHYT domain
CBR72_RS20175	COG5001	Diguanylate cyclase
CBR72_RS20180	COG0840	transmembrane signaling receptor activity
CBR72_RS20190	COG1960	acyl-CoA dehydrogenase activity
CBR72_RS20195	COG2079	MmgE PrpD family protein
CBR72_RS20205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CBR72_RS20210	COG1561	YicC-like family, N-terminal region
CBR72_RS20225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR72_RS20230	COG0791	NLP P60 protein
CBR72_RS20235	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS20240	COG0194	GDP metabolic process
CBR72_RS20245	COG1758	RNA polymerase activity
CBR72_RS20250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR72_RS20255	COG1126	abc transporter atp-binding protein
CBR72_RS20260	COG0765	amino acid transport
CBR72_RS20265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS20290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS20305	COG2831	hemolysin activation secretion protein
CBR72_RS20315	COG3188	usher protein
CBR72_RS20320	COG3121	Chaperone
CBR72_RS20330	COG3064	Membrane
CBR72_RS20330	COG3210	domain, Protein
CBR72_RS20330	COG3210	domain, Protein
CBR72_RS20330	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS20330	COG3064	Membrane
CBR72_RS20330	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS20340	COG4181	ATPase activity
CBR72_RS20350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR72_RS20355	COG0584	glycerophosphoryl diester phosphodiesterase
CBR72_RS20360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CBR72_RS20370	COG0678	peroxiredoxin activity
CBR72_RS20370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR72_RS20385	COG0789	Transcriptional regulator
CBR72_RS20390	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBR72_RS20415	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR72_RS20425	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBR72_RS20445	COG3618	amidohydrolase
CBR72_RS20450	COG0583	DNA-binding transcription factor activity
CBR72_RS20455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBR72_RS20460	COG2252	PERMEase
CBR72_RS20465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR72_RS20470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR72_RS20500	COG0583	DNA-binding transcription factor activity
CBR72_RS20505	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBR72_RS20510	COG0488	(ABC) transporter
CBR72_RS20515	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR72_RS20520	COG0590	tRNA wobble adenosine to inosine editing
CBR72_RS20535	COG1320	monovalent cation:proton antiporter activity
CBR72_RS20540	COG2212	antiporter activity
CBR72_RS20550	COG0651	ATP synthesis coupled electron transport
CBR72_RS20555	COG1006	Multisubunit Na H antiporter MnhC subunit
CBR72_RS20560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CBR72_RS20560	COG2111	Na H antiporter
CBR72_RS20565	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS20575	COG0420	3'-5' exonuclease activity
CBR72_RS20580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR72_RS20585	COG1522	sequence-specific DNA binding
CBR72_RS20600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBR72_RS20625	COG2130	NADP-dependent
CBR72_RS20640	COG1131	(ABC) transporter
CBR72_RS20645	COG0842	Transport permease protein
CBR72_RS20655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBR72_RS20690	COG0235	Class ii aldolase
CBR72_RS20695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR72_RS20700	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS20710	COG1414	Transcriptional regulator
CBR72_RS20715	COG0602	queuosine metabolic process
CBR72_RS20720	COG0720	synthase
CBR72_RS20730	COG1289	transmembrane transporter activity
CBR72_RS20740	COG1566	PFAM secretion protein HlyD family protein
CBR72_RS20750	COG0400	carboxylic ester hydrolase activity
CBR72_RS20755	COG0840	transmembrane signaling receptor activity
CBR72_RS20770	COG0587	DNA-directed DNA polymerase activity
CBR72_RS20780	COG0390	transport system, permease component
CBR72_RS20785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR72_RS20790	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CBR72_RS20830	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBR72_RS20840	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS20845	COG1280	lysine exporter protein (LysE YggA)
CBR72_RS20850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR72_RS20870	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CBR72_RS20895	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS20920	COG0583	DNA-binding transcription factor activity
CBR72_RS20935	COG1522	sequence-specific DNA binding
CBR72_RS20945	COG2814	Major facilitator Superfamily
CBR72_RS20960	COG1396	sequence-specific DNA binding
CBR72_RS20980	COG0183	Belongs to the thiolase family
CBR72_RS20990	COG0583	DNA-binding transcription factor activity
CBR72_RS20995	COG2814	Major facilitator Superfamily
CBR72_RS21000	COG0656	L-ascorbic acid biosynthetic process
CBR72_RS21010	COG2807	transmembrane transport
CBR72_RS21020	COG1595	DNA-templated transcription, initiation
CBR72_RS21025	COG3712	iron ion homeostasis
CBR72_RS21030	COG4774	siderophore transport
CBR72_RS21035	COG2814	Major facilitator Superfamily
CBR72_RS21040	COG0583	DNA-binding transcription factor activity
CBR72_RS21045	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS21055	COG1349	DNA-binding transcription factor activity
CBR72_RS21065	COG1012	belongs to the aldehyde dehydrogenase family
CBR72_RS21075	COG0411	ABC transporter
CBR72_RS21145	COG1475	DNA binding
CBR72_RS21165	COG0582	viral genome integration into host DNA
CBR72_RS21170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR72_RS21170	COG0519	Catalyzes the synthesis of GMP from XMP
CBR72_RS21185	COG1695	Transcriptional regulator
CBR72_RS21200	COG2072	flavoprotein involved in K transport
CBR72_RS21205	COG0601	transmembrane transport
CBR72_RS21215	COG0444	Belongs to the ABC transporter superfamily
CBR72_RS21220	COG4608	Belongs to the ABC transporter superfamily
CBR72_RS21225	COG0747	negative chemotaxis
CBR72_RS21265	COG0047	phosphoribosylformylglycinamidine synthase activity
CBR72_RS21265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBR72_RS21275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR72_RS21280	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR72_RS21280	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR72_RS21285	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR72_RS21295	COG0613	PHP domain protein
CBR72_RS21320	COG2501	S4 domain
CBR72_RS21325	COG0084	hydrolase, TatD family'
CBR72_RS21330	COG1136	(ABC) transporter
CBR72_RS21345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBR72_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS21360	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBR72_RS21370	COG1309	transcriptional regulator
CBR72_RS21375	COG1022	Amp-dependent synthetase and ligase
CBR72_RS21405	COG1024	Enoyl-CoA hydratase
CBR72_RS21410	COG1803	Methylglyoxal synthase
CBR72_RS21420	COG2975	iron-sulfur cluster assembly
CBR72_RS21425	COG0633	Ferredoxin
CBR72_RS21430	COG0443	Heat shock 70 kDa protein
CBR72_RS21435	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBR72_RS21440	COG0316	Belongs to the HesB IscA family
CBR72_RS21445	COG0822	iron-sulfur transferase activity
CBR72_RS21450	COG1104	cysteine desulfurase activity
CBR72_RS21460	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CBR72_RS21465	COG0556	nucleotide-excision repair
CBR72_RS21475	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBR72_RS21480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR72_RS21485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBR72_RS21490	COG0740	serine-type endopeptidase activity
CBR72_RS21495	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBR72_RS21505	COG1278	Cold shock
CBR72_RS21515	COG1278	Cold shock
CBR72_RS21550	COG2171	N-acyltransferase activity
CBR72_RS21555	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR72_RS21560	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR72_RS21565	COG0488	(ABC) transporter
CBR72_RS21570	COG0210	DNA helicase
CBR72_RS21585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR72_RS21585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR72_RS21590	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBR72_RS21595	COG0196	riboflavin kinase activity
CBR72_RS21600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBR72_RS21605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBR72_RS21610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBR72_RS21620	COG1522	sequence-specific DNA binding
CBR72_RS21635	COG0586	Pfam SNARE associated Golgi protein
CBR72_RS21645	COG0756	dUTP diphosphatase activity
CBR72_RS21650	COG1902	pentaerythritol trinitrate reductase activity
CBR72_RS21655	COG1126	abc transporter atp-binding protein
CBR72_RS21660	COG0765	amino acid transport
CBR72_RS21665	COG0765	amino acid transport
CBR72_RS21670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR72_RS21680	COG2423	ornithine cyclodeaminase activity
CBR72_RS21685	COG1764	response to oxidative stress
CBR72_RS21690	COG1914	H( )-stimulated, divalent metal cation uptake system
CBR72_RS21695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBR72_RS21700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBR72_RS21715	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBR72_RS21720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBR72_RS21725	COG2197	response regulator
CBR72_RS21730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR72_RS21750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS21755	COG0840	transmembrane signaling receptor activity
CBR72_RS21905	COG2369	cell adhesion
CBR72_RS21915	COG5410	chromosome segregation
CBR72_RS22075	COG0582	viral genome integration into host DNA
CBR72_RS22085	COG0135	phosphoribosylanthranilate isomerase activity
CBR72_RS22090	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR72_RS22095	COG0101	tRNA pseudouridine synthase activity
CBR72_RS22105	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBR72_RS22110	COG0473	3-isopropylmalate dehydrogenase activity
CBR72_RS22115	COG0066	3-isopropylmalate dehydratase activity
CBR72_RS22125	COG2197	response regulator
CBR72_RS22140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBR72_RS22150	COG2205	protein histidine kinase activity
CBR72_RS22160	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBR72_RS22170	COG1295	ribonuclease BN
CBR72_RS22180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBR72_RS22210	COG1450	Type ii and iii secretion system protein
CBR72_RS22245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR72_RS22285	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS22300	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS22330	COG0181	hydroxymethylbilane synthase activity
CBR72_RS22335	COG0861	Integral membrane protein TerC family
CBR72_RS22340	COG0861	Integral membrane protein TerC family
CBR72_RS22345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CBR72_RS22350	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR72_RS22360	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR72_RS22370	COG2137	regulation of response to DNA damage stimulus
CBR72_RS22375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBR72_RS22400	COG2974	May be involved in recombination
CBR72_RS22405	COG0540	Belongs to the ATCase OTCase family
CBR72_RS22435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR72_RS22465	COG0500	methyltransferase
CBR72_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS22485	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR72_RS22490	COG0747	negative chemotaxis
CBR72_RS22510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR72_RS22535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR72_RS22565	COG0811	peptide transport
CBR72_RS22600	COG2188	Transcriptional regulator
CBR72_RS22605	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS22620	COG0583	DNA-binding transcription factor activity
CBR72_RS22630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR72_RS22640	COG4172	Belongs to the ABC transporter superfamily
CBR72_RS22650	COG0601	transmembrane transport
CBR72_RS22655	COG4166	transmembrane transport
CBR72_RS22660	COG2267	carboxylic ester hydrolase activity
CBR72_RS22665	COG4638	Rieske (2fe-2S)
CBR72_RS22675	COG0583	DNA-binding transcription factor activity
CBR72_RS22680	COG2146	nitrite reductase [NAD(P)H] activity
CBR72_RS22685	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR72_RS22690	COG1595	DNA-templated transcription, initiation
CBR72_RS22695	COG3712	iron ion homeostasis
CBR72_RS22700	COG4774	siderophore transport
CBR72_RS22725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR72_RS22735	COG3246	L-lysine catabolic process to acetate
CBR72_RS22740	COG3181	Tripartite tricarboxylate transporter family receptor
CBR72_RS22755	COG1028	Short-chain dehydrogenase reductase Sdr
CBR72_RS22760	COG0583	DNA-binding transcription factor activity
CBR72_RS22790	COG0457	Tetratricopeptide repeat
CBR72_RS22795	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CBR72_RS22800	COG1215	transferase activity, transferring glycosyl groups
CBR72_RS22805	COG1215	transferase activity, transferring glycosyl groups
CBR72_RS22810	COG1215	transferase activity, transferring glycosyl groups
CBR72_RS22815	COG0003	Pfam Anion-transporting ATPase
CBR72_RS22835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR72_RS22875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBR72_RS22890	COG1215	transferase activity, transferring glycosyl groups
CBR72_RS22900	COG3307	-O-antigen