locus-tag	class	description
FOB29_RS00005	COG2137	regulation of response to DNA damage stimulus
FOB29_RS00015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB29_RS00025	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB29_RS00030	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOB29_RS00035	COG0861	Integral membrane protein TerC family
FOB29_RS00040	COG0861	Integral membrane protein TerC family
FOB29_RS00045	COG0181	hydroxymethylbilane synthase activity
FOB29_RS00075	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS00090	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS00130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB29_RS00165	COG1450	Type ii and iii secretion system protein
FOB29_RS00195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FOB29_RS00205	COG1295	ribonuclease BN
FOB29_RS00215	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOB29_RS00225	COG2205	protein histidine kinase activity
FOB29_RS00235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOB29_RS00250	COG2197	response regulator
FOB29_RS00260	COG0066	3-isopropylmalate dehydratase activity
FOB29_RS00265	COG0473	3-isopropylmalate dehydrogenase activity
FOB29_RS00270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOB29_RS00280	COG0101	tRNA pseudouridine synthase activity
FOB29_RS00285	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOB29_RS00290	COG0135	phosphoribosylanthranilate isomerase activity
FOB29_RS00300	COG0582	viral genome integration into host DNA
FOB29_RS00330	COG0419	ATPase involved in DNA repair
FOB29_RS00380	COG1396	sequence-specific DNA binding
FOB29_RS00465	COG5410	chromosome segregation
FOB29_RS00625	COG0840	transmembrane signaling receptor activity
FOB29_RS00630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS00650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB29_RS00655	COG2197	response regulator
FOB29_RS00660	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOB29_RS00665	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOB29_RS00680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOB29_RS00685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOB29_RS00690	COG1914	H( )-stimulated, divalent metal cation uptake system
FOB29_RS00695	COG1764	response to oxidative stress
FOB29_RS00700	COG2423	ornithine cyclodeaminase activity
FOB29_RS00710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS00715	COG0765	amino acid transport
FOB29_RS00720	COG0765	amino acid transport
FOB29_RS00725	COG1126	abc transporter atp-binding protein
FOB29_RS00730	COG1902	pentaerythritol trinitrate reductase activity
FOB29_RS00735	COG0756	dUTP diphosphatase activity
FOB29_RS00745	COG0586	Pfam SNARE associated Golgi protein
FOB29_RS00760	COG1522	sequence-specific DNA binding
FOB29_RS00770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FOB29_RS00775	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOB29_RS00780	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOB29_RS00785	COG0196	riboflavin kinase activity
FOB29_RS00790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOB29_RS00795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB29_RS00795	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB29_RS00810	COG0210	DNA helicase
FOB29_RS00815	COG0488	(ABC) transporter
FOB29_RS00820	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB29_RS00825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB29_RS00830	COG2171	N-acyltransferase activity
FOB29_RS00855	COG3468	outer membrane autotransporter barrel domain protein
FOB29_RS00885	COG1278	Cold shock
FOB29_RS00895	COG1278	Cold shock
FOB29_RS00905	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOB29_RS00910	COG0740	serine-type endopeptidase activity
FOB29_RS00915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOB29_RS00920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOB29_RS00925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOB29_RS00935	COG0556	nucleotide-excision repair
FOB29_RS00940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOB29_RS00950	COG1104	cysteine desulfurase activity
FOB29_RS00955	COG0822	iron-sulfur transferase activity
FOB29_RS00960	COG0316	Belongs to the HesB IscA family
FOB29_RS00965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOB29_RS00970	COG0443	Heat shock 70 kDa protein
FOB29_RS00975	COG0633	Ferredoxin
FOB29_RS00980	COG2975	iron-sulfur cluster assembly
FOB29_RS00990	COG1803	Methylglyoxal synthase
FOB29_RS00995	COG1024	Enoyl-CoA hydratase
FOB29_RS01025	COG1022	Amp-dependent synthetase and ligase
FOB29_RS01030	COG1309	transcriptional regulator
FOB29_RS01040	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOB29_RS01045	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS01055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOB29_RS01070	COG1136	(ABC) transporter
FOB29_RS01075	COG0084	hydrolase, TatD family'
FOB29_RS01080	COG2501	S4 domain
FOB29_RS01105	COG0613	PHP domain protein
FOB29_RS01115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS01120	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB29_RS01120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB29_RS01125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB29_RS01135	COG0047	phosphoribosylformylglycinamidine synthase activity
FOB29_RS01135	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FOB29_RS01175	COG0747	negative chemotaxis
FOB29_RS01180	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS01185	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS01195	COG0601	transmembrane transport
FOB29_RS01200	COG2072	flavoprotein involved in K transport
FOB29_RS01215	COG1695	Transcriptional regulator
FOB29_RS01230	COG0519	Catalyzes the synthesis of GMP from XMP
FOB29_RS01230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB29_RS01250	COG5489	Protein of unknown function (DUF736)
FOB29_RS01265	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS01270	COG0384	phenazine biosynthesis protein PhzF
FOB29_RS01310	COG0411	ABC transporter
FOB29_RS01320	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS01330	COG1349	DNA-binding transcription factor activity
FOB29_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS01345	COG0583	DNA-binding transcription factor activity
FOB29_RS01350	COG2814	Major facilitator Superfamily
FOB29_RS01355	COG4774	siderophore transport
FOB29_RS01360	COG3712	iron ion homeostasis
FOB29_RS01365	COG1595	DNA-templated transcription, initiation
FOB29_RS01370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB29_RS01380	COG4585	Histidine kinase
FOB29_RS01415	COG0653	protein targeting
FOB29_RS01430	COG1309	transcriptional regulator
FOB29_RS01445	COG1024	Enoyl-CoA hydratase
FOB29_RS01450	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS01465	COG2207	Transcriptional regulator
FOB29_RS01470	COG2807	transmembrane transport
FOB29_RS01480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS01485	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS01490	COG0656	L-ascorbic acid biosynthetic process
FOB29_RS01495	COG2814	Major facilitator Superfamily
FOB29_RS01500	COG0583	DNA-binding transcription factor activity
FOB29_RS01505	COG0183	Belongs to the thiolase family
FOB29_RS01525	COG1396	sequence-specific DNA binding
FOB29_RS01540	COG2814	Major facilitator Superfamily
FOB29_RS01550	COG1522	sequence-specific DNA binding
FOB29_RS01565	COG0583	DNA-binding transcription factor activity
FOB29_RS01590	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS01615	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FOB29_RS01635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB29_RS01640	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS01645	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS01655	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FOB29_RS01695	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FOB29_RS01700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB29_RS01705	COG0390	transport system, permease component
FOB29_RS01715	COG0587	DNA-directed DNA polymerase activity
FOB29_RS01730	COG0840	transmembrane signaling receptor activity
FOB29_RS01735	COG0400	carboxylic ester hydrolase activity
FOB29_RS01745	COG1566	PFAM secretion protein HlyD family protein
FOB29_RS01755	COG1289	transmembrane transporter activity
FOB29_RS01765	COG0720	synthase
FOB29_RS01770	COG0602	queuosine metabolic process
FOB29_RS01775	COG1414	Transcriptional regulator
FOB29_RS01785	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS01790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB29_RS01795	COG0235	Class ii aldolase
FOB29_RS01830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FOB29_RS01840	COG0842	Transport permease protein
FOB29_RS01845	COG1131	(ABC) transporter
FOB29_RS01885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB29_RS01900	COG1522	sequence-specific DNA binding
FOB29_RS01905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB29_RS01910	COG0420	3'-5' exonuclease activity
FOB29_RS01920	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS01925	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOB29_RS01925	COG2111	Na H antiporter
FOB29_RS01930	COG1006	Multisubunit Na H antiporter MnhC subunit
FOB29_RS01935	COG0651	ATP synthesis coupled electron transport
FOB29_RS01945	COG2212	antiporter activity
FOB29_RS01950	COG1320	monovalent cation:proton antiporter activity
FOB29_RS01965	COG0590	tRNA wobble adenosine to inosine editing
FOB29_RS01970	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB29_RS01975	COG0488	(ABC) transporter
FOB29_RS01980	COG0655	NAD(P)H dehydrogenase (quinone) activity
FOB29_RS01985	COG0583	DNA-binding transcription factor activity
FOB29_RS02015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB29_RS02020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB29_RS02025	COG2252	PERMEase
FOB29_RS02030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FOB29_RS02035	COG0583	DNA-binding transcription factor activity
FOB29_RS02040	COG3618	amidohydrolase
FOB29_RS02060	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOB29_RS02070	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB29_RS02095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOB29_RS02100	COG0789	Transcriptional regulator
FOB29_RS02115	COG0678	peroxiredoxin activity
FOB29_RS02115	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB29_RS02125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FOB29_RS02130	COG0584	glycerophosphoryl diester phosphodiesterase
FOB29_RS02135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB29_RS02145	COG4181	ATPase activity
FOB29_RS02155	COG3064	Membrane
FOB29_RS02155	COG3210	domain, Protein
FOB29_RS02155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FOB29_RS02155	COG3064	Membrane
FOB29_RS02155	COG3210	domain, Protein
FOB29_RS02155	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FOB29_RS02165	COG3121	Chaperone
FOB29_RS02170	COG3188	usher protein
FOB29_RS02180	COG2831	hemolysin activation secretion protein
FOB29_RS02195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS02220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS02225	COG0765	amino acid transport
FOB29_RS02230	COG1126	abc transporter atp-binding protein
FOB29_RS02235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB29_RS02240	COG1758	RNA polymerase activity
FOB29_RS02245	COG0194	GDP metabolic process
FOB29_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS02255	COG0791	NLP P60 protein
FOB29_RS02260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB29_RS02275	COG1561	YicC-like family, N-terminal region
FOB29_RS02280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOB29_RS02290	COG2079	MmgE PrpD family protein
FOB29_RS02295	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS02305	COG0840	transmembrane signaling receptor activity
FOB29_RS02310	COG5001	Diguanylate cyclase
FOB29_RS02310	COG3300	MHYT domain
FOB29_RS02315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOB29_RS02320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOB29_RS02325	COG0174	glutamine synthetase
FOB29_RS02330	COG3852	Histidine kinase
FOB29_RS02345	COG2205	protein histidine kinase activity
FOB29_RS02345	COG5002	protein histidine kinase activity
FOB29_RS02345	COG0784	Response regulator, receiver
FOB29_RS02360	COG0583	DNA-binding transcription factor activity
FOB29_RS02365	COG1741	Belongs to the pirin family
FOB29_RS02370	COG1741	Belongs to the pirin family
FOB29_RS02375	COG3842	ATPase activity
FOB29_RS02385	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB29_RS02405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOB29_RS02410	COG0583	DNA-binding transcription factor activity
FOB29_RS02455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB29_RS02470	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FOB29_RS02480	COG0783	Belongs to the Dps family
FOB29_RS02495	COG1216	Glycosyl transferase, family 2
FOB29_RS02515	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS02530	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB29_RS02545	COG3842	ATPase activity
FOB29_RS02550	COG0395	ABC-type sugar transport system, permease component
FOB29_RS02555	COG1175	transmembrane transport
FOB29_RS02570	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FOB29_RS02580	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS02600	COG1794	racemase activity, acting on amino acids and derivatives
FOB29_RS02610	COG0625	glutathione transferase activity
FOB29_RS02615	COG2133	pyrroloquinoline quinone binding
FOB29_RS02625	COG0697	spore germination
FOB29_RS02630	COG2363	Small membrane protein
FOB29_RS02650	COG1464	Belongs to the NlpA lipoprotein family
FOB29_RS02660	COG0688	phosphatidylethanolamine metabolic process
FOB29_RS02670	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS02680	COG0028	Belongs to the TPP enzyme family
FOB29_RS02690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB29_RS02690	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB29_RS02700	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS02705	COG2186	Transcriptional regulator
FOB29_RS02710	COG3189	MarR family transcriptional regulator
FOB29_RS02715	COG2985	domain, Protein
FOB29_RS02720	COG0076	glutamate decarboxylase activity
FOB29_RS02725	COG2814	Major facilitator Superfamily
FOB29_RS02730	COG2205	protein histidine kinase activity
FOB29_RS02730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS02735	COG2197	response regulator
FOB29_RS02740	COG2203	Gaf domain
FOB29_RS02740	COG5001	Diguanylate cyclase
FOB29_RS02740	COG4251	negative regulation of phosphorylation
FOB29_RS02740	COG3706	GGDEF domain
FOB29_RS02750	COG1253	flavin adenine dinucleotide binding
FOB29_RS02765	COG1595	DNA-templated transcription, initiation
FOB29_RS02775	COG2200	EAL domain
FOB29_RS02795	COG0410	ABC transporter
FOB29_RS02820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS02825	COG0765	amino acid transport
FOB29_RS02830	COG1126	abc transporter atp-binding protein
FOB29_RS02860	COG1619	proteins homologs of microcin C7 resistance protein MccF
FOB29_RS02870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB29_RS02885	COG2819	hydrolase of the alpha beta superfamily
FOB29_RS02910	COG0683	leucine binding
FOB29_RS02925	COG0431	NADPH-dependent FMN reductase
FOB29_RS02935	COG1024	Enoyl-CoA hydratase
FOB29_RS02945	COG2267	carboxylic ester hydrolase activity
FOB29_RS02955	COG0318	PFAM AMP-dependent synthetase and ligase
FOB29_RS02985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB29_RS02995	COG2271	Major facilitator Superfamily
FOB29_RS03000	COG0154	amidase activity
FOB29_RS03015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS03020	COG0318	PFAM AMP-dependent synthetase and ligase
FOB29_RS03025	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS03030	COG0183	Belongs to the thiolase family
FOB29_RS03035	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS03035	COG1024	Enoyl-CoA hydratase
FOB29_RS03045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS03055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS03065	COG1024	Enoyl-CoA hydratase
FOB29_RS03075	COG0583	DNA-binding transcription factor activity
FOB29_RS03080	COG1454	alcohol dehydrogenase
FOB29_RS03085	COG2175	clavaminate synthase activity
FOB29_RS03110	COG1063	alcohol dehydrogenase
FOB29_RS03115	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS03120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS03125	COG0601	transmembrane transport
FOB29_RS03130	COG0747	negative chemotaxis
FOB29_RS03135	COG0402	S-adenosylhomocysteine deaminase activity
FOB29_RS03175	COG1129	ABC transporter
FOB29_RS03180	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS03195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FOB29_RS03205	COG1137	ATPase activity
FOB29_RS03225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB29_RS03230	COG0477	Major facilitator Superfamily
FOB29_RS03235	COG0583	DNA-binding transcription factor activity
FOB29_RS03240	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOB29_RS03245	COG2204	response regulator
FOB29_RS03250	COG0028	Belongs to the TPP enzyme family
FOB29_RS03270	COG5265	(ABC) transporter
FOB29_RS03285	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS03300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB29_RS03310	COG2192	nodulation
FOB29_RS03345	COG1216	Glycosyl transferase, family 2
FOB29_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS03360	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FOB29_RS03365	COG3685	Protein conserved in bacteria
FOB29_RS03395	COG1640	4-alpha-glucanotransferase
FOB29_RS03400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB29_RS03410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOB29_RS03425	COG0297	glycogen (starch) synthase activity
FOB29_RS03430	COG0668	transmembrane transport
FOB29_RS03440	COG1058	Belongs to the CinA family
FOB29_RS03440	COG1546	Belongs to the CinA family
FOB29_RS03455	COG0166	Belongs to the GPI family
FOB29_RS03460	COG0392	lysyltransferase activity
FOB29_RS03465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB29_RS03470	COG3568	Endonuclease Exonuclease Phosphatase
FOB29_RS03475	COG2863	cytochrome
FOB29_RS03500	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS03520	COG1937	Protein conserved in bacteria
FOB29_RS03545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB29_RS03565	COG3665	Urea carboxylase-associated protein
FOB29_RS03580	COG0765	amino acid transport
FOB29_RS03585	COG0765	amino acid transport
FOB29_RS03590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS03600	COG2182	Extracellular solute-binding protein
FOB29_RS03605	COG1175	transmembrane transport
FOB29_RS03610	COG3833	ABC-type maltose transport systems, permease component
FOB29_RS03620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB29_RS03625	COG3842	ATPase activity
FOB29_RS03630	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB29_RS03635	COG4948	Mandelate Racemase Muconate Lactonizing
FOB29_RS03640	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS03645	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOB29_RS03650	COG0066	3-isopropylmalate dehydratase activity
FOB29_RS03700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS03735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB29_RS03770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB29_RS03775	COG0456	acetyltransferase
FOB29_RS03790	COG2900	Belongs to the SlyX family
FOB29_RS03795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB29_RS03810	COG1122	ATPase activity
FOB29_RS03855	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS03860	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS03875	COG1024	Enoyl-CoA hydratase
FOB29_RS03890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS03905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOB29_RS03905	COG0519	Catalyzes the synthesis of GMP from XMP
FOB29_RS03925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB29_RS03935	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS03940	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS03945	COG0583	DNA-binding transcription factor activity
FOB29_RS03950	COG0477	Major facilitator Superfamily
FOB29_RS03955	COG0028	Belongs to the TPP enzyme family
FOB29_RS03960	COG0583	DNA-binding transcription factor activity
FOB29_RS04010	COG1802	Transcriptional regulator
FOB29_RS04020	COG3959	Transketolase, thiamine diphosphate binding domain
FOB29_RS04025	COG3958	Transketolase
FOB29_RS04055	COG3258	Cytochrome c
FOB29_RS04060	COG3042	response to heat
FOB29_RS04070	COG2733	membrane
FOB29_RS04095	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FOB29_RS04115	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOB29_RS04125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS04130	COG0842	Transport permease protein
FOB29_RS04130	COG1129	ABC transporter
FOB29_RS04135	COG0842	Transport permease protein
FOB29_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS04165	COG2259	Doxx family
FOB29_RS04170	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS04215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS04240	COG0386	Belongs to the glutathione peroxidase family
FOB29_RS04265	COG0095	Lipoate-protein ligase
FOB29_RS04275	COG0740	serine-type endopeptidase activity
FOB29_RS04285	COG0640	Transcriptional regulator
FOB29_RS04290	COG2059	Chromate
FOB29_RS04300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB29_RS04305	COG4221	oxidoreductase activity
FOB29_RS04325	COG0010	Belongs to the arginase family
FOB29_RS04330	COG1126	abc transporter atp-binding protein
FOB29_RS04335	COG0765	amino acid transport
FOB29_RS04340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS04355	COG0084	hydrolase, TatD family'
FOB29_RS04365	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOB29_RS04370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOB29_RS04390	COG1024	Enoyl-CoA hydratase
FOB29_RS04390	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS04395	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS04400	COG2914	Belongs to the UPF0125 (RnfH) family
FOB29_RS04410	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOB29_RS04435	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FOB29_RS04445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB29_RS04450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FOB29_RS04455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB29_RS04465	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOB29_RS04470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB29_RS04480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB29_RS04485	COG0750	zinc metalloprotease
FOB29_RS04490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOB29_RS04495	COG0575	Belongs to the CDS family
FOB29_RS04500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOB29_RS04505	COG0233	cytoplasmic translational termination
FOB29_RS04510	COG0528	UMP kinase activity
FOB29_RS04515	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOB29_RS04520	COG0052	Belongs to the universal ribosomal protein uS2 family
FOB29_RS04525	COG0024	Methionine aminopeptidase
FOB29_RS04530	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOB29_RS04550	COG1286	toxin biosynthetic process
FOB29_RS04560	COG0285	dihydrofolate synthase activity
FOB29_RS04570	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS04595	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOB29_RS04615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOB29_RS04625	COG1677	Flagellar hook-basal body complex protein FliE
FOB29_RS04630	COG1766	The M ring may be actively involved in energy transduction
FOB29_RS04635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB29_RS04640	COG1317	bacterial-type flagellum organization
FOB29_RS04650	COG2882	bacterial-type flagellum organization
FOB29_RS04660	COG1580	Controls the rotational direction of flagella during chemotaxis
FOB29_RS04670	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FOB29_RS04695	COG0840	transmembrane signaling receptor activity
FOB29_RS04700	COG0840	transmembrane signaling receptor activity
FOB29_RS04710	COG0840	transmembrane signaling receptor activity
FOB29_RS04715	COG0840	transmembrane signaling receptor activity
FOB29_RS04725	COG1256	bacterial-type flagellum assembly
FOB29_RS04735	COG1706	bacterial-type flagellum-dependent cell motility
FOB29_RS04755	COG1749	Flagellar hook protein flgE
FOB29_RS04780	COG2747	anti-sigma28 factor FlgM
FOB29_RS04805	COG0840	transmembrane signaling receptor activity
FOB29_RS04810	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOB29_RS04815	COG0745	RESPONSE REGULATOR receiver
FOB29_RS04820	COG2201	protein-glutamate methylesterase activity
FOB29_RS04825	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOB29_RS04830	COG0840	transmembrane signaling receptor activity
FOB29_RS04845	COG0745	RESPONSE REGULATOR receiver
FOB29_RS04890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB29_RS04895	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB29_RS04900	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FOB29_RS04910	COG4566	intracellular signal transduction
FOB29_RS04915	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOB29_RS04920	COG0339	signal peptide processing
FOB29_RS04930	COG1999	signal sequence binding
FOB29_RS04955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS04965	COG1187	pseudouridine synthase activity
FOB29_RS04970	COG3161	chorismate lyase activity
FOB29_RS04980	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS04990	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS04995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS05000	COG0601	transmembrane transport
FOB29_RS05005	COG0747	negative chemotaxis
FOB29_RS05015	COG0583	DNA-binding transcription factor activity
FOB29_RS05030	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FOB29_RS05030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB29_RS05035	COG0668	transmembrane transport
FOB29_RS05040	COG0165	Argininosuccinate lyase
FOB29_RS05045	COG0778	Nitroreductase
FOB29_RS05050	COG0789	Transcriptional regulator
FOB29_RS05060	COG0501	Belongs to the peptidase M48B family
FOB29_RS05065	COG2267	carboxylic ester hydrolase activity
FOB29_RS05095	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS05100	COG0154	amidase activity
FOB29_RS05145	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS05150	COG0129	dihydroxy-acid dehydratase activity
FOB29_RS05160	COG0583	DNA-binding transcription factor activity
FOB29_RS05165	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS05170	COG3246	L-lysine catabolic process to acetate
FOB29_RS05175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB29_RS05195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOB29_RS05220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB29_RS05235	COG0667	Aldo Keto reductase
FOB29_RS05240	COG0656	L-ascorbic acid biosynthetic process
FOB29_RS05245	COG5265	(ABC) transporter
FOB29_RS05295	COG1522	sequence-specific DNA binding
FOB29_RS05320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOB29_RS05360	COG0776	regulation of translation
FOB29_RS05365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB29_RS05365	COG0072	phenylalanine-tRNA ligase activity
FOB29_RS05370	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOB29_RS05375	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOB29_RS05380	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOB29_RS05400	COG0347	Belongs to the P(II) protein family
FOB29_RS05405	COG0004	ammonium transporteR
FOB29_RS05415	COG2271	Major facilitator Superfamily
FOB29_RS05445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB29_RS05445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FOB29_RS05445	COG0506	proline dehydrogenase activity
FOB29_RS05455	COG3008	intermembrane lipid transfer
FOB29_RS05460	COG2995	paraquat-inducible protein a
FOB29_RS05465	COG0542	response to heat
FOB29_RS05470	COG4953	penicillin-binding protein 1C
FOB29_RS05480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOB29_RS05485	COG1278	Cold shock
FOB29_RS05495	COG0183	Belongs to the thiolase family
FOB29_RS05500	COG0038	chloride channel
FOB29_RS05505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FOB29_RS05510	COG1570	exodeoxyribonuclease VII activity
FOB29_RS05515	COG0811	peptide transport
FOB29_RS05525	COG1663	tetraacyldisaccharide 4'-kinase activity
FOB29_RS05530	COG2835	tetraacyldisaccharide 4'-kinase activity
FOB29_RS05535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOB29_RS05540	COG0563	adenylate kinase activity
FOB29_RS05550	COG0728	peptidoglycan biosynthetic process
FOB29_RS05575	COG0268	Binds directly to 16S ribosomal RNA
FOB29_RS05580	COG3836	Belongs to the HpcH HpaI aldolase family
FOB29_RS05600	COG2186	Transcriptional regulator
FOB29_RS05615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB29_RS05625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB29_RS05630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOB29_RS05635	COG0137	argininosuccinate synthase activity
FOB29_RS05645	COG3158	transport of potassium into the cell
FOB29_RS05650	COG0642	Histidine kinase
FOB29_RS05680	COG0776	regulation of translation
FOB29_RS05690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOB29_RS05695	COG0557	exoribonuclease II activity
FOB29_RS05725	COG0679	Auxin Efflux Carrier
FOB29_RS05730	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FOB29_RS05735	COG2391	methyltransferase activity
FOB29_RS05740	COG0069	glutamate synthase activity
FOB29_RS05745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB29_RS05755	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FOB29_RS05760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOB29_RS05785	COG3706	GGDEF domain
FOB29_RS05795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB29_RS05825	COG3909	cytochrome
FOB29_RS05835	COG0625	glutathione transferase activity
FOB29_RS05840	COG0730	response to heat
FOB29_RS05845	COG0482	sulfurtransferase activity
FOB29_RS05850	COG0583	DNA-binding transcription factor activity
FOB29_RS05855	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS05880	COG0247	lactate metabolic process
FOB29_RS05885	COG0277	FAD linked oxidase domain protein
FOB29_RS05890	COG0277	FAD linked oxidase domain protein
FOB29_RS05895	COG0277	FAD linked oxidase domain protein
FOB29_RS05900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOB29_RS05905	COG0312	modulator of DNA gyrase
FOB29_RS05920	COG0308	aminopeptidase N
FOB29_RS05925	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOB29_RS05945	COG0436	Aminotransferase
FOB29_RS05950	COG3737	Protein of unknown function (DUF498/DUF598)
FOB29_RS05955	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOB29_RS05960	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOB29_RS05965	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOB29_RS05975	COG0305	Participates in initiation and elongation during chromosome replication
FOB29_RS05985	COG0359	binds to the 23S rRNA
FOB29_RS05990	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOB29_RS05995	COG2965	DNA replication, synthesis of RNA primer
FOB29_RS06000	COG0360	Binds together with S18 to 16S ribosomal RNA
FOB29_RS06005	COG1469	GTP cyclohydrolase I activity
FOB29_RS06010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOB29_RS06015	COG0142	geranyltranstransferase activity
FOB29_RS06020	COG1722	exodeoxyribonuclease VII activity
FOB29_RS06060	COG0501	Belongs to the peptidase M48B family
FOB29_RS06080	COG1846	Transcriptional regulator
FOB29_RS06090	COG1566	PFAM secretion protein HlyD family protein
FOB29_RS06095	COG2814	Major facilitator Superfamily
FOB29_RS06100	COG0473	3-isopropylmalate dehydrogenase activity
FOB29_RS06110	COG0747	negative chemotaxis
FOB29_RS06115	COG0601	transmembrane transport
FOB29_RS06120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS06125	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS06130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB29_RS06155	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS06160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB29_RS06165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS06170	COG0433	COG0433 Predicted ATPase
FOB29_RS06175	COG0217	transcriptional regulatory protein
FOB29_RS06180	COG0151	Belongs to the GarS family
FOB29_RS06190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOB29_RS06195	COG0799	negative regulation of ribosome biogenesis
FOB29_RS06200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOB29_RS06205	COG0424	maF-like protein
FOB29_RS06210	COG1301	dicarboxylic acid transport
FOB29_RS06215	COG4191	Histidine kinase
FOB29_RS06220	COG2204	response regulator
FOB29_RS06245	COG1418	mRNA catabolic process
FOB29_RS06250	COG0500	methyltransferase
FOB29_RS06255	COG0477	Major facilitator Superfamily
FOB29_RS06265	COG0583	DNA-binding transcription factor activity
FOB29_RS06295	COG1530	ribonuclease E activity
FOB29_RS06305	COG1132	(ABC) transporter
FOB29_RS06345	COG0726	polysaccharide deacetylase
FOB29_RS06350	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS06365	COG1643	Atp-dependent helicase
FOB29_RS06370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB29_RS06370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOB29_RS06375	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOB29_RS06380	COG0704	Plays a role in the regulation of phosphate uptake
FOB29_RS06385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOB29_RS06390	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS06395	COG1322	Protein conserved in bacteria
FOB29_RS06405	COG2094	Belongs to the DNA glycosylase MPG family
FOB29_RS06410	COG1393	Belongs to the ArsC family
FOB29_RS06415	COG1177	transmembrane transport
FOB29_RS06420	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB29_RS06425	COG3842	ATPase activity
FOB29_RS06435	COG3642	lipopolysaccharide core region biosynthetic process
FOB29_RS06445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FOB29_RS06450	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS06460	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB29_RS06460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB29_RS06465	COG1802	Transcriptional regulator
FOB29_RS06480	COG3437	response regulator, receiver
FOB29_RS06485	COG2198	Histidine kinase
FOB29_RS06485	COG5002	protein histidine kinase activity
FOB29_RS06485	COG0784	Response regulator, receiver
FOB29_RS06510	COG1126	abc transporter atp-binding protein
FOB29_RS06530	COG2050	protein possibly involved in aromatic compounds catabolism
FOB29_RS06535	COG1024	Enoyl-CoA hydratase
FOB29_RS06540	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS06545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB29_RS06550	COG2151	metal-sulfur cluster biosynthetic enzyme
FOB29_RS06555	COG3396	Phenylacetate-CoA oxygenase
FOB29_RS06560	COG3460	Phenylacetate-CoA oxygenase
FOB29_RS06565	COG3396	Phenylacetate-CoA oxygenase
FOB29_RS06580	COG0583	DNA-binding transcription factor activity
FOB29_RS06590	COG1335	isochorismatase
FOB29_RS06595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOB29_RS06600	COG0501	Belongs to the peptidase M48B family
FOB29_RS06605	COG1162	GTPase activity
FOB29_RS06610	COG3622	Belongs to the hyi family
FOB29_RS06615	COG0494	nUDIX hydrolase
FOB29_RS06620	COG0335	large ribosomal subunit rRNA binding
FOB29_RS06640	COG2895	sulfate adenylyltransferase (ATP) activity
FOB29_RS06650	COG0175	sulfate reduction
FOB29_RS06655	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB29_RS06660	COG4208	sulfate ABC transporter
FOB29_RS06665	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FOB29_RS06670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FOB29_RS06675	COG0450	alkyl hydroperoxide reductase
FOB29_RS06680	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS06685	COG2985	domain, Protein
FOB29_RS06700	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOB29_RS06705	COG2951	lytic endotransglycosylase activity
FOB29_RS06715	COG0587	DNA-directed DNA polymerase activity
FOB29_RS06720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOB29_RS06725	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FOB29_RS06730	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOB29_RS06750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOB29_RS06755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOB29_RS06760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB29_RS06765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB29_RS06770	COG0077	Prephenate dehydratase
FOB29_RS06770	COG1605	Chorismate mutase
FOB29_RS06775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOB29_RS06790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOB29_RS06855	COG3706	GGDEF domain
FOB29_RS06865	COG0589	response to stress
FOB29_RS06875	COG2951	lytic endotransglycosylase activity
FOB29_RS06880	COG2833	Protein of unknown function (DUF455)
FOB29_RS06885	COG0297	glycogen (starch) synthase activity
FOB29_RS06895	COG1132	(ABC) transporter
FOB29_RS06900	COG0189	ligase activity
FOB29_RS06900	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB29_RS06905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB29_RS06905	COG0189	ligase activity
FOB29_RS06910	COG3038	cytochrome b561
FOB29_RS06915	COG3237	CsbD-like
FOB29_RS06925	COG2823	Periplasmic or secreted lipoprotein
FOB29_RS06940	COG0672	)-iron permease
FOB29_RS06955	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FOB29_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS06965	COG3243	poly(R)-hydroxyalkanoic acid synthase
FOB29_RS06975	COG0564	pseudouridine synthase activity
FOB29_RS07015	COG1199	ATP-dependent helicase activity
FOB29_RS07020	COG2183	response to ionizing radiation
FOB29_RS07045	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOB29_RS07050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB29_RS07055	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB29_RS07060	COG0567	Dehydrogenase, E1 component
FOB29_RS07065	COG1297	OPT oligopeptide transporter protein
FOB29_RS07075	COG0280	phosphate acetyltransferase
FOB29_RS07075	COG0281	malic enzyme
FOB29_RS07080	COG4774	siderophore transport
FOB29_RS07085	COG3128	pkhd-type hydroxylase
FOB29_RS07110	COG1840	ABC-type Fe3 transport system, periplasmic component
FOB29_RS07115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB29_RS07125	COG3842	ATPase activity
FOB29_RS07130	COG0583	DNA-binding transcription factor activity
FOB29_RS07135	COG0372	Belongs to the citrate synthase family
FOB29_RS07140	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FOB29_RS07145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOB29_RS07150	COG1053	succinate dehydrogenase
FOB29_RS07155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOB29_RS07160	COG2009	succinate dehydrogenase
FOB29_RS07165	COG2188	Transcriptional regulator
FOB29_RS07170	COG0039	L-malate dehydrogenase activity
FOB29_RS07190	COG1981	membrane
FOB29_RS07210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB29_RS07215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB29_RS07225	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FOB29_RS07240	COG0148	phosphopyruvate hydratase activity
FOB29_RS07250	COG0504	CTP synthase activity
FOB29_RS07270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS07275	COG0601	transmembrane transport
FOB29_RS07280	COG0747	negative chemotaxis
FOB29_RS07285	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS07290	COG1446	asparaginase
FOB29_RS07330	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FOB29_RS07340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB29_RS07350	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FOB29_RS07355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOB29_RS07360	COG0791	NLP P60 protein
FOB29_RS07370	COG0583	DNA-binding transcription factor activity
FOB29_RS07385	COG0583	DNA-binding transcription factor activity
FOB29_RS07395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOB29_RS07415	COG1381	Involved in DNA repair and RecF pathway recombination
FOB29_RS07420	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOB29_RS07425	COG0571	ribonuclease III activity
FOB29_RS07430	COG0681	Belongs to the peptidase S26 family
FOB29_RS07435	COG0481	GTPase activity
FOB29_RS07440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB29_RS07465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOB29_RS07470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOB29_RS07475	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS07485	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB29_RS07495	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOB29_RS07500	COG1399	metal-binding, possibly nucleic acid-binding protein
FOB29_RS07505	COG0424	maF-like protein
FOB29_RS07515	COG3023	N-Acetylmuramoyl-L-alanine amidase
FOB29_RS07520	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOB29_RS07525	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOB29_RS07530	COG0546	phosphoglycolate phosphatase activity
FOB29_RS07535	COG0564	pseudouridine synthase activity
FOB29_RS07540	COG1530	ribonuclease E activity
FOB29_RS07545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FOB29_RS07550	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOB29_RS07555	COG0159	tryptophan synthase activity
FOB29_RS07575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOB29_RS07580	COG3228	Belongs to the MtfA family
FOB29_RS07590	COG0251	oxidation-reduction process
FOB29_RS07615	COG2878	Part of a membrane complex involved in electron transport
FOB29_RS07620	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOB29_RS07625	COG0411	ABC transporter
FOB29_RS07655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB29_RS07685	COG1268	BioY protein
FOB29_RS07690	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FOB29_RS07695	COG1122	ATPase activity
FOB29_RS07700	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB29_RS07705	COG2917	probably involved in intracellular septation
FOB29_RS07710	COG0271	Belongs to the BolA IbaG family
FOB29_RS07715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB29_RS07720	COG0625	glutathione transferase activity
FOB29_RS07730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS07735	COG0765	amino acid transport
FOB29_RS07745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOB29_RS07755	COG1196	nuclear chromosome segregation
FOB29_RS07760	COG0477	Major facilitator Superfamily
FOB29_RS07765	COG1573	uracil-dna glycosylase
FOB29_RS07770	COG1214	PFAM Peptidase M22, glycoprotease
FOB29_RS07785	COG0450	alkyl hydroperoxide reductase
FOB29_RS07790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS07795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOB29_RS07800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOB29_RS07805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOB29_RS07810	COG0560	Phosphoserine phosphatase
FOB29_RS07820	COG1007	ATP synthesis coupled electron transport
FOB29_RS07835	COG0713	ATP synthesis coupled electron transport
FOB29_RS07845	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB29_RS07850	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOB29_RS07855	COG1034	ATP synthesis coupled electron transport
FOB29_RS07865	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FOB29_RS07870	COG0649	NAD binding
FOB29_RS07875	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB29_RS07880	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB29_RS07885	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOB29_RS07890	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS07910	COG0671	phosphoesterase, PA-phosphatase related
FOB29_RS07920	COG1597	lipid kinase activity
FOB29_RS07920	COG1803	Methylglyoxal synthase
FOB29_RS07930	COG2084	Dehydrogenase
FOB29_RS07945	COG0583	DNA-binding transcription factor activity
FOB29_RS07980	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FOB29_RS07985	COG4251	negative regulation of phosphorylation
FOB29_RS07985	COG5001	Diguanylate cyclase
FOB29_RS07985	COG3706	GGDEF domain
FOB29_RS07985	COG2203	Gaf domain
FOB29_RS07990	COG2201	protein-glutamate methylesterase activity
FOB29_RS08015	COG0840	transmembrane signaling receptor activity
FOB29_RS08030	COG0330	HflC and HflK could
FOB29_RS08050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB29_RS08050	COG0475	glutathione-regulated potassium exporter activity
FOB29_RS08060	COG2207	Transcriptional regulator
FOB29_RS08120	COG0582	viral genome integration into host DNA
FOB29_RS08140	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOB29_RS08150	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOB29_RS08155	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOB29_RS08160	COG0330	HflC and HflK could
FOB29_RS08165	COG0330	HflC and HflK could
FOB29_RS08170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOB29_RS08175	COG1923	regulation of RNA biosynthetic process
FOB29_RS08180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB29_RS08185	COG1160	GTP binding
FOB29_RS08190	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB29_RS08195	COG2976	Protein conserved in bacteria
FOB29_RS08200	COG0124	histidyl-tRNA synthetase
FOB29_RS08215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB29_RS08220	COG0105	UTP biosynthetic process
FOB29_RS08225	COG0525	valine-tRNA ligase activity
FOB29_RS08230	COG0336	Belongs to the RNA methyltransferase TrmD family
FOB29_RS08235	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOB29_RS08240	COG0228	four-way junction DNA binding
FOB29_RS08250	COG0425	Belongs to the sulfur carrier protein TusA family
FOB29_RS08255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB29_RS08305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB29_RS08310	COG0543	2 iron, 2 sulfur cluster binding
FOB29_RS08310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOB29_RS08315	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOB29_RS08320	COG2076	Multidrug Resistance protein
FOB29_RS08325	COG3217	Mosc domain protein beta barrel domain protein
FOB29_RS08325	COG0633	Ferredoxin
FOB29_RS08330	COG5285	phytanoyl-CoA dioxygenase
FOB29_RS08335	COG0662	Cupin 2, conserved barrel domain protein
FOB29_RS08345	COG0456	acetyltransferase
FOB29_RS08360	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS08365	COG2358	TRAP transporter, solute receptor (TAXI family
FOB29_RS08375	COG2311	Membrane
FOB29_RS08400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FOB29_RS08410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOB29_RS08415	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FOB29_RS08420	COG1760	l-serine dehydratase
FOB29_RS08425	COG1283	sodium-dependent phosphate transmembrane transporter activity
FOB29_RS08430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FOB29_RS08435	COG0412	Dienelactone hydrolase
FOB29_RS08440	COG0428	transporter
FOB29_RS08445	COG0477	Major facilitator Superfamily
FOB29_RS08450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FOB29_RS08455	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB29_RS08460	COG1845	cytochrome c oxidase, subunit III
FOB29_RS08465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB29_RS08475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB29_RS08475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FOB29_RS08495	COG0183	Belongs to the thiolase family
FOB29_RS08510	COG4176	ABC-type proline glycine betaine transport system permease component
FOB29_RS08520	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOB29_RS08525	COG2814	Major facilitator Superfamily
FOB29_RS08530	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOB29_RS08535	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOB29_RS08555	COG1846	Transcriptional regulator
FOB29_RS08560	COG2814	Major facilitator Superfamily
FOB29_RS08565	COG0495	leucyl-tRNA aminoacylation
FOB29_RS08580	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOB29_RS08595	COG0154	amidase activity
FOB29_RS08610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS08660	COG0583	DNA-binding transcription factor activity
FOB29_RS08665	COG0427	acetyl-CoA hydrolase
FOB29_RS08670	COG0583	DNA-binding transcription factor activity
FOB29_RS08675	COG3264	Mechanosensitive ion channel
FOB29_RS08675	COG1511	domain protein
FOB29_RS08685	COG4221	oxidoreductase activity
FOB29_RS08710	COG2176	DNA-directed DNA polymerase activity
FOB29_RS08730	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB29_RS08735	COG3384	dioxygenase
FOB29_RS08750	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOB29_RS08755	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS08810	COG4964	Belongs to the GSP D family
FOB29_RS08840	COG5001	Diguanylate cyclase
FOB29_RS08840	COG3300	MHYT domain
FOB29_RS08855	COG1846	Transcriptional regulator
FOB29_RS08900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FOB29_RS08910	COG2070	2-Nitropropane dioxygenase
FOB29_RS08920	COG2610	gluconate transmembrane transporter activity
FOB29_RS08930	COG0456	acetyltransferase
FOB29_RS08940	COG1408	metallophosphoesterase
FOB29_RS08945	COG3064	Membrane
FOB29_RS08960	COG3128	pkhd-type hydroxylase
FOB29_RS08970	COG4774	siderophore transport
FOB29_RS08980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB29_RS09025	COG0583	DNA-binding transcription factor activity
FOB29_RS09030	COG2814	Major facilitator Superfamily
FOB29_RS09040	COG0148	phosphopyruvate hydratase activity
FOB29_RS09050	COG1301	dicarboxylic acid transport
FOB29_RS09065	COG2159	amidohydrolase
FOB29_RS09075	COG0583	DNA-binding transcription factor activity
FOB29_RS09090	COG1024	Enoyl-CoA hydratase
FOB29_RS09095	COG2186	Transcriptional regulator
FOB29_RS09100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS09105	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOB29_RS09115	COG0235	Class ii aldolase
FOB29_RS09145	COG0833	amino acid
FOB29_RS09160	COG5265	(ABC) transporter
FOB29_RS09180	COG0840	transmembrane signaling receptor activity
FOB29_RS09195	COG1360	Flagellar Motor Protein
FOB29_RS09210	COG1971	Probably functions as a manganese efflux pump
FOB29_RS09215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB29_RS09225	COG1959	2 iron, 2 sulfur cluster binding
FOB29_RS09235	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOB29_RS09240	COG2814	Major facilitator Superfamily
FOB29_RS09250	COG3284	Transcriptional regulator
FOB29_RS09255	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS09275	COG2207	Transcriptional regulator
FOB29_RS09280	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS09285	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS09320	COG0583	DNA-binding transcription factor activity
FOB29_RS09325	COG0747	negative chemotaxis
FOB29_RS09335	COG0625	glutathione transferase activity
FOB29_RS09380	COG1595	DNA-templated transcription, initiation
FOB29_RS09385	COG3712	iron ion homeostasis
FOB29_RS09390	COG4774	siderophore transport
FOB29_RS09400	COG2814	Major facilitator Superfamily
FOB29_RS09405	COG2197	response regulator
FOB29_RS09425	COG0583	DNA-binding transcription factor activity
FOB29_RS09435	COG0154	amidase activity
FOB29_RS09440	COG4133	protoheme IX ABC transporter activity
FOB29_RS09460	COG1024	Enoyl-CoA hydratase
FOB29_RS09475	COG1309	transcriptional regulator
FOB29_RS09500	COG0411	ABC transporter
FOB29_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS09535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOB29_RS09545	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB29_RS09550	COG1024	Enoyl-CoA hydratase
FOB29_RS09555	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOB29_RS09555	COG0022	dehydrogenase e1 component
FOB29_RS09560	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOB29_RS09565	COG0402	S-adenosylhomocysteine deaminase activity
FOB29_RS09575	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB29_RS09580	COG2188	Transcriptional regulator
FOB29_RS09595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB29_RS09600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB29_RS09610	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB29_RS09615	COG3585	molybdate ion transport
FOB29_RS09660	COG0583	DNA-binding transcription factor activity
FOB29_RS09665	COG4948	Mandelate Racemase Muconate Lactonizing
FOB29_RS09670	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS09685	COG2814	Major facilitator Superfamily
FOB29_RS09695	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS09710	COG2301	Belongs to the HpcH HpaI aldolase family
FOB29_RS09715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS09730	COG2205	protein histidine kinase activity
FOB29_RS09750	COG2863	cytochrome
FOB29_RS09755	COG3258	Cytochrome c
FOB29_RS09775	COG1538	Outer membrane efflux protein
FOB29_RS09780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB29_RS09785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS09795	COG3210	domain, Protein
FOB29_RS09800	COG2205	protein histidine kinase activity
FOB29_RS09810	COG0683	leucine binding
FOB29_RS09815	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS09845	COG2301	Belongs to the HpcH HpaI aldolase family
FOB29_RS09850	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS09855	COG0427	acetyl-CoA hydrolase
FOB29_RS09885	COG0583	DNA-binding transcription factor activity
FOB29_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS09950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS09975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOB29_RS10000	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOB29_RS10010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOB29_RS10015	COG1538	Outer membrane efflux protein
FOB29_RS10020	COG1136	(ABC) transporter
FOB29_RS10020	COG0577	efflux transmembrane transporter activity
FOB29_RS10025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS10040	COG0259	pyridoxamine-phosphate oxidase activity
FOB29_RS10045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB29_RS10050	COG0579	oxidoreductase
FOB29_RS10060	COG3210	domain, Protein
FOB29_RS10070	COG0405	Gamma-glutamyltransferase
FOB29_RS10080	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS10090	COG0114	fumarate hydratase activity
FOB29_RS10100	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOB29_RS10105	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FOB29_RS10105	COG3064	Membrane
FOB29_RS10105	COG3210	domain, Protein
FOB29_RS10105	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FOB29_RS10105	COG3064	Membrane
FOB29_RS10105	COG3210	domain, Protein
FOB29_RS10110	COG0586	Pfam SNARE associated Golgi protein
FOB29_RS10115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOB29_RS10120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOB29_RS10125	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOB29_RS10140	COG0617	tRNA 3'-terminal CCA addition
FOB29_RS10170	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FOB29_RS10180	COG1024	Enoyl-CoA hydratase
FOB29_RS10185	COG0752	glycyl-tRNA synthetase alpha subunit
FOB29_RS10190	COG0751	glycine-tRNA ligase activity
FOB29_RS10195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOB29_RS10200	COG0204	Acyl-transferase
FOB29_RS10210	COG0583	DNA-binding transcription factor activity
FOB29_RS10215	COG1053	succinate dehydrogenase
FOB29_RS10215	COG3976	FMN-binding domain protein
FOB29_RS10235	COG0242	peptide deformylase activity
FOB29_RS10240	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS10245	COG0700	Nucleoside recognition
FOB29_RS10250	COG0469	pyruvate kinase activity
FOB29_RS10255	COG1929	Belongs to the glycerate kinase type-1 family
FOB29_RS10265	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOB29_RS10270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB29_RS10275	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOB29_RS10285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FOB29_RS10295	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOB29_RS10310	COG0667	Aldo Keto reductase
FOB29_RS10320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB29_RS10325	COG4106	trans-aconitate 2-methyltransferase activity
FOB29_RS10335	COG0737	Belongs to the 5'-nucleotidase family
FOB29_RS10340	COG0583	DNA-binding transcription factor activity
FOB29_RS10360	COG0410	ABC transporter
FOB29_RS10375	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS10390	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS10430	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB29_RS10435	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FOB29_RS10465	COG2982	Protein involved in outer membrane biogenesis
FOB29_RS10470	COG2818	Glycosylase
FOB29_RS10475	COG0727	PFAM Uncharacterised protein family (UPF0153)
FOB29_RS10500	COG0402	S-adenosylhomocysteine deaminase activity
FOB29_RS10505	COG0604	alcohol dehydrogenase
FOB29_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS10505	COG3321	synthase
FOB29_RS10510	COG0156	8-amino-7-oxononanoate synthase activity
FOB29_RS10515	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOB29_RS10535	COG0300	oxidoreductase activity
FOB29_RS10550	COG2011	ABC-type metal ion transport system permease component
FOB29_RS10555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FOB29_RS10560	COG1501	Belongs to the glycosyl hydrolase 31 family
FOB29_RS10565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOB29_RS10565	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FOB29_RS10575	COG0318	PFAM AMP-dependent synthetase and ligase
FOB29_RS10580	COG1473	amidohydrolase
FOB29_RS10585	COG0583	DNA-binding transcription factor activity
FOB29_RS10590	COG2855	membrane
FOB29_RS10600	COG2239	Acts as a magnesium transporter
FOB29_RS10615	COG1522	sequence-specific DNA binding
FOB29_RS10640	COG0653	protein targeting
FOB29_RS10645	COG0739	heme binding
FOB29_RS10660	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOB29_RS10675	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FOB29_RS10680	COG1181	Belongs to the D-alanine--D-alanine ligase family
FOB29_RS10685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB29_RS10690	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOB29_RS10700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOB29_RS10705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB29_RS10710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FOB29_RS10720	COG3116	cell division
FOB29_RS10725	COG0275	rRNA processing
FOB29_RS10730	COG2001	Belongs to the MraZ family
FOB29_RS10740	COG0488	(ABC) transporter
FOB29_RS10745	COG0418	dihydroorotase activity
FOB29_RS10750	COG1473	amidohydrolase
FOB29_RS10800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOB29_RS10805	COG4654	Cytochrome c, class I
FOB29_RS10810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FOB29_RS10845	COG1309	transcriptional regulator
FOB29_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS10855	COG2084	Dehydrogenase
FOB29_RS10860	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOB29_RS10875	COG1024	Enoyl-CoA hydratase
FOB29_RS10880	COG1414	Transcriptional regulator
FOB29_RS10910	COG0442	prolyl-tRNA aminoacylation
FOB29_RS10915	COG0824	Thioesterase
FOB29_RS10920	COG0811	peptide transport
FOB29_RS10925	COG0848	biopolymer transport protein
FOB29_RS10935	COG0823	Involved in the tonB-independent uptake of proteins
FOB29_RS10960	COG1522	sequence-specific DNA binding
FOB29_RS10970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB29_RS10985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS10990	COG0697	spore germination
FOB29_RS11000	COG1073	alpha beta
FOB29_RS11015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FOB29_RS11020	COG0463	Glycosyl transferase, family 2
FOB29_RS11040	COG0842	Transport permease protein
FOB29_RS11045	COG0842	Transport permease protein
FOB29_RS11045	COG1129	ABC transporter
FOB29_RS11050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS11060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOB29_RS11065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB29_RS11075	COG0328	RNA-DNA hybrid ribonuclease activity
FOB29_RS11080	COG2226	methyltransferase
FOB29_RS11085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOB29_RS11090	COG1388	LysM domain
FOB29_RS11090	COG0741	lytic transglycosylase activity
FOB29_RS11100	COG2979	Protein of unknown function (DUF533)
FOB29_RS11140	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS11145	COG2816	NAD+ diphosphatase activity
FOB29_RS11160	COG0589	response to stress
FOB29_RS11165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FOB29_RS11165	COG2146	nitrite reductase [NAD(P)H] activity
FOB29_RS11175	COG2116	formate transmembrane transporter activity
FOB29_RS11180	COG0515	serine threonine protein kinase
FOB29_RS11190	COG3707	response regulator
FOB29_RS11200	COG0165	Argininosuccinate lyase
FOB29_RS11215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOB29_RS11220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOB29_RS11225	COG0251	oxidation-reduction process
FOB29_RS11230	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB29_RS11245	COG0583	DNA-binding transcription factor activity
FOB29_RS11255	COG0477	Major facilitator Superfamily
FOB29_RS11270	COG4948	Mandelate Racemase Muconate Lactonizing
FOB29_RS11290	COG2719	SpoVR family
FOB29_RS11295	COG2718	Belongs to the UPF0229 family
FOB29_RS11300	COG2766	serine protein kinase
FOB29_RS11310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB29_RS11310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOB29_RS11315	COG1335	isochorismatase
FOB29_RS11325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOB29_RS11330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOB29_RS11340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOB29_RS11350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FOB29_RS11355	COG0316	Belongs to the HesB IscA family
FOB29_RS11365	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOB29_RS11370	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOB29_RS11375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOB29_RS11380	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOB29_RS11390	COG0312	modulator of DNA gyrase
FOB29_RS11395	COG3028	Belongs to the UPF0307 family
FOB29_RS11420	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB29_RS11470	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB29_RS11470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB29_RS11470	COG1042	CoA-binding domain protein
FOB29_RS11470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB29_RS11470	COG0045	succinate-CoA ligase (ADP-forming) activity
FOB29_RS11470	COG1042	CoA-binding domain protein
FOB29_RS11475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB29_RS11480	COG2814	Major facilitator Superfamily
FOB29_RS11490	COG1522	sequence-specific DNA binding
FOB29_RS11520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB29_RS11525	COG1696	Membrane protein involved in D-alanine export
FOB29_RS11550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOB29_RS11560	COG2264	protein methyltransferase activity
FOB29_RS11565	COG0439	Biotin carboxylase
FOB29_RS11570	COG0511	ligase activity, forming carbon-carbon bonds
FOB29_RS11575	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB29_RS11580	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB29_RS11590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOB29_RS11595	COG3150	esterase
FOB29_RS11600	COG0557	exoribonuclease II activity
FOB29_RS11610	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOB29_RS11615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOB29_RS11625	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB29_RS11650	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOB29_RS11655	COG1678	Uncharacterized ACR, COG1678
FOB29_RS11670	COG0352	thiamine-phosphate diphosphorylase activity
FOB29_RS11675	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB29_RS11705	COG1024	Enoyl-CoA hydratase
FOB29_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS11745	COG0411	ABC transporter
FOB29_RS11780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FOB29_RS11790	COG2816	NAD+ diphosphatase activity
FOB29_RS11795	COG3539	Fimbrial protein
FOB29_RS11820	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOB29_RS11825	COG0237	dephospho-CoA kinase activity
FOB29_RS11830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOB29_RS11845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOB29_RS11850	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FOB29_RS11860	COG0477	Major facilitator Superfamily
FOB29_RS11880	COG1126	abc transporter atp-binding protein
FOB29_RS11885	COG0765	amino acid transport
FOB29_RS11890	COG4597	amino acid ABC transporter
FOB29_RS11895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS11900	COG2884	Cell division ATP-binding protein ftsE
FOB29_RS11905	COG2177	Part of the ABC transporter FtsEX involved in
FOB29_RS11910	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FOB29_RS11920	COG1194	a g-specific adenine glycosylase
FOB29_RS11935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB29_RS11950	COG2226	methyltransferase
FOB29_RS11960	COG4206	TonB-dependent receptor
FOB29_RS11965	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOB29_RS11970	COG2022	thiamine diphosphate biosynthetic process
FOB29_RS11975	COG0351	phosphomethylpyrimidine kinase
FOB29_RS11980	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB29_RS11985	COG1538	Outer membrane efflux protein
FOB29_RS11990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FOB29_RS12000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOB29_RS12015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB29_RS12050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB29_RS12085	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS12090	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOB29_RS12105	COG2226	methyltransferase
FOB29_RS12110	COG0745	RESPONSE REGULATOR receiver
FOB29_RS12115	COG5002	protein histidine kinase activity
FOB29_RS12125	COG5002	protein histidine kinase activity
FOB29_RS12135	COG2132	Multicopper oxidase
FOB29_RS12150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB29_RS12165	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FOB29_RS12170	COG1984	allophanate hydrolase subunit 2
FOB29_RS12180	COG1802	Transcriptional regulator
FOB29_RS12190	COG1238	metal cluster binding
FOB29_RS12195	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB29_RS12200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS12215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB29_RS12220	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FOB29_RS12225	COG4988	ABC transporter
FOB29_RS12235	COG1294	oxidase, subunit
FOB29_RS12250	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FOB29_RS12260	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOB29_RS12275	COG1137	ATPase activity
FOB29_RS12280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FOB29_RS12290	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOB29_RS12305	COG1660	Displays ATPase and GTPase activities
FOB29_RS12325	COG0792	nuclease activity
FOB29_RS12330	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOB29_RS12335	COG2823	Periplasmic or secreted lipoprotein
FOB29_RS12350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOB29_RS12360	COG1309	transcriptional regulator
FOB29_RS12365	COG0471	metal ion transport
FOB29_RS12370	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOB29_RS12375	COG0772	Belongs to the SEDS family
FOB29_RS12380	COG0768	penicillin binding
FOB29_RS12390	COG1792	Involved in formation and maintenance of cell shape
FOB29_RS12395	COG1077	Cell shape determining protein MreB Mrl
FOB29_RS12400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB29_RS12405	COG0154	amidase activity
FOB29_RS12410	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOB29_RS12415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOB29_RS12420	COG0708	Exodeoxyribonuclease III
FOB29_RS12425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOB29_RS12430	COG2860	membrane
FOB29_RS12440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS12445	COG2223	nitrite transmembrane transporter activity
FOB29_RS12450	COG2813	Specifically methylates the guanine in position
FOB29_RS12450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB29_RS12455	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB29_RS12460	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOB29_RS12480	COG2918	glutathione biosynthetic process
FOB29_RS12505	COG3245	cytochrome
FOB29_RS12510	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS12520	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS12525	COG1309	transcriptional regulator
FOB29_RS12530	COG2070	2-Nitropropane dioxygenase
FOB29_RS12535	COG1024	Enoyl-CoA hydratase
FOB29_RS12540	COG1024	Enoyl-CoA hydratase
FOB29_RS12545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOB29_RS12555	COG0747	negative chemotaxis
FOB29_RS12565	COG0601	transmembrane transport
FOB29_RS12570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS12575	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS12580	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS12595	COG0210	DNA helicase
FOB29_RS12600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOB29_RS12605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOB29_RS12615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOB29_RS12620	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOB29_RS12625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOB29_RS12630	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOB29_RS12635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOB29_RS12640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOB29_RS12650	COG0356	it plays a direct role in the translocation of protons across the membrane
FOB29_RS12665	COG1024	Enoyl-CoA hydratase
FOB29_RS12685	COG0037	tRNA processing
FOB29_RS12695	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB29_RS12700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS12705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FOB29_RS12710	COG2967	ApaG domain
FOB29_RS12715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FOB29_RS12720	COG0546	phosphoglycolate phosphatase activity
FOB29_RS12730	COG0512	Glutamine amidotransferase of anthranilate synthase
FOB29_RS12735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOB29_RS12740	COG0134	indole-3-glycerol-phosphate synthase activity
FOB29_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS12760	COG0583	DNA-binding transcription factor activity
FOB29_RS12780	COG3276	selenocysteine insertion sequence binding
FOB29_RS12795	COG2864	formate dehydrogenase
FOB29_RS12800	COG0437	4 iron, 4 sulfur cluster binding
FOB29_RS12815	COG1607	acyl-coa hydrolase
FOB29_RS12845	COG1595	DNA-templated transcription, initiation
FOB29_RS12850	COG3712	iron ion homeostasis
FOB29_RS12860	COG3720	iron ion transport
FOB29_RS12865	COG4558	Periplasmic binding protein
FOB29_RS12870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB29_RS12875	COG1120	ATPase activity
FOB29_RS12890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS12895	COG1683	Conserved Protein
FOB29_RS12905	COG1335	isochorismatase
FOB29_RS12910	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FOB29_RS12915	COG1473	amidohydrolase
FOB29_RS12925	COG0583	DNA-binding transcription factor activity
FOB29_RS12935	COG3145	DNA-N1-methyladenine dioxygenase activity
FOB29_RS12940	COG2169	Transcriptional regulator
FOB29_RS12940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOB29_RS12965	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS12975	COG0443	Heat shock 70 kDa protein
FOB29_RS12980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOB29_RS13005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS13010	COG1671	Belongs to the UPF0178 family
FOB29_RS13020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOB29_RS13095	COG1902	pentaerythritol trinitrate reductase activity
FOB29_RS13105	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS13140	COG2124	cytochrome p450
FOB29_RS13235	COG1522	sequence-specific DNA binding
FOB29_RS13250	COG2814	Major facilitator Superfamily
FOB29_RS13255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB29_RS13275	COG1999	signal sequence binding
FOB29_RS13280	COG0109	protoheme IX farnesyltransferase activity
FOB29_RS13320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB29_RS13330	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FOB29_RS13335	COG1609	Transcriptional regulator
FOB29_RS13345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB29_RS13350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOB29_RS13365	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FOB29_RS13380	COG0069	glutamate synthase activity
FOB29_RS13380	COG0070	glutamate synthase
FOB29_RS13380	COG0067	glutamate synthase
FOB29_RS13390	COG3047	cAMP biosynthetic process
FOB29_RS13395	COG1127	ABC transporter
FOB29_RS13400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB29_RS13405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOB29_RS13420	COG1131	(ABC) transporter
FOB29_RS13425	COG0842	Transport permease protein
FOB29_RS13435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOB29_RS13440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOB29_RS13445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB29_RS13450	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOB29_RS13455	COG0131	Imidazoleglycerol-phosphate dehydratase
FOB29_RS13465	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOB29_RS13470	COG0107	imidazoleglycerol-phosphate synthase activity
FOB29_RS13475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOB29_RS13480	COG0140	phosphoribosyl-ATP diphosphatase activity
FOB29_RS13485	COG0537	adenosine 5'-monophosphoramidase activity
FOB29_RS13490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB29_RS13495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOB29_RS13505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOB29_RS13510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FOB29_RS13515	COG1970	mechanosensitive ion channel activity
FOB29_RS13520	COG0723	plastoquinol--plastocyanin reductase activity
FOB29_RS13525	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOB29_RS13530	COG2857	Cytochrome c1
FOB29_RS13535	COG0625	glutathione transferase activity
FOB29_RS13540	COG2969	positive regulation of protein catabolic process
FOB29_RS13550	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB29_RS13565	COG0697	spore germination
FOB29_RS13585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB29_RS13595	COG0601	transmembrane transport
FOB29_RS13600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS13610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FOB29_RS13620	COG0513	Belongs to the DEAD box helicase family
FOB29_RS13625	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS13630	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOB29_RS13650	COG0583	DNA-binding transcription factor activity
FOB29_RS13660	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOB29_RS13670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB29_RS13675	COG0154	amidase activity
FOB29_RS13700	COG3842	ATPase activity
FOB29_RS13705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOB29_RS13710	COG3842	ATPase activity
FOB29_RS13715	COG1653	transport
FOB29_RS13720	COG1175	transmembrane transport
FOB29_RS13725	COG0395	ABC-type sugar transport system, permease component
FOB29_RS13740	COG0018	arginyl-trna synthetase
FOB29_RS13750	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOB29_RS13755	COG2200	EAL domain
FOB29_RS13785	COG1473	amidohydrolase
FOB29_RS13790	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS13795	COG0183	Belongs to the thiolase family
FOB29_RS13800	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FOB29_RS13815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOB29_RS13825	COG2358	TRAP transporter, solute receptor (TAXI family
FOB29_RS13835	COG1629	transport
FOB29_RS13840	COG2922	Belongs to the Smg family
FOB29_RS13845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB29_RS13865	COG3842	ATPase activity
FOB29_RS13870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB29_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS13880	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS13890	COG0028	Belongs to the TPP enzyme family
FOB29_RS13895	COG1522	sequence-specific DNA binding
FOB29_RS13900	COG3781	membrane
FOB29_RS13910	COG0702	epimerase
FOB29_RS13930	COG2910	NAD(P)H-binding
FOB29_RS13935	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB29_RS13950	COG3845	ABC transporter
FOB29_RS13955	COG4603	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS13960	COG1079	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS13965	COG0402	S-adenosylhomocysteine deaminase activity
FOB29_RS13970	COG0625	glutathione transferase activity
FOB29_RS13980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS14005	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS14010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS14025	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FOB29_RS14030	COG1304	FMN binding
FOB29_RS14035	COG1254	Belongs to the acylphosphatase family
FOB29_RS14040	COG1309	transcriptional regulator
FOB29_RS14055	COG0592	DNA-directed DNA polymerase activity
FOB29_RS14060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOB29_RS14065	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOB29_RS14070	COG0594	ribonuclease P activity
FOB29_RS14075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOB29_RS14080	COG0706	membrane insertase activity
FOB29_RS14085	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOB29_RS14090	COG1473	amidohydrolase
FOB29_RS14095	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS14100	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS14105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS14110	COG0601	transmembrane transport
FOB29_RS14120	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOB29_RS14125	COG0582	viral genome integration into host DNA
FOB29_RS14135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOB29_RS14165	COG1111	helicase
FOB29_RS14165	COG1205	dead DEAH box helicase
FOB29_RS14170	COG0210	DNA helicase
FOB29_RS14180	COG3093	addiction module antidote protein HigA
FOB29_RS14190	COG1505	serine-type exopeptidase activity
FOB29_RS14200	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOB29_RS14210	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB29_RS14220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS14225	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS14240	COG0280	phosphate acetyltransferase
FOB29_RS14240	COG0281	malic enzyme
FOB29_RS14275	COG0583	DNA-binding transcription factor activity
FOB29_RS14280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB29_RS14295	COG0436	Aminotransferase
FOB29_RS14300	COG1278	Cold shock
FOB29_RS14305	COG0445	tRNA wobble uridine modification
FOB29_RS14310	COG0357	Ribosomal RNA small subunit methyltransferase G
FOB29_RS14315	COG1192	Involved in chromosome partitioning
FOB29_RS14320	COG1475	DNA binding
FOB29_RS14325	COG0252	asparaginase activity
FOB29_RS14345	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB29_RS14355	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB29_RS14365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOB29_RS14370	COG0081	regulation of translation
FOB29_RS14375	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOB29_RS14380	COG0222	ribosome binding
FOB29_RS14385	COG0085	RNA polymerase activity
FOB29_RS14390	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOB29_RS14425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOB29_RS14430	COG0049	tRNA binding
FOB29_RS14435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOB29_RS14440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOB29_RS14445	COG0051	transcription antitermination factor activity, RNA binding
FOB29_RS14450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOB29_RS14455	COG0088	Forms part of the polypeptide exit tunnel
FOB29_RS14460	COG0089	rRNA binding
FOB29_RS14465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOB29_RS14470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOB29_RS14475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOB29_RS14480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOB29_RS14485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOB29_RS14490	COG0255	Belongs to the universal ribosomal protein uL29 family
FOB29_RS14495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOB29_RS14510	COG1131	(ABC) transporter
FOB29_RS14525	COG2267	carboxylic ester hydrolase activity
FOB29_RS14550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOB29_RS14555	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOB29_RS14560	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOB29_RS14565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOB29_RS14570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOB29_RS14575	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOB29_RS14580	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOB29_RS14585	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOB29_RS14590	COG1841	ribosomal large subunit assembly
FOB29_RS14595	COG0200	Binds to the 23S rRNA
FOB29_RS14600	COG0201	protein transport
FOB29_RS14605	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB29_RS14610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FOB29_RS14615	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOB29_RS14620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOB29_RS14625	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOB29_RS14630	COG0202	RNA polymerase activity
FOB29_RS14635	COG0203	ribosomal protein L17
FOB29_RS14645	COG1324	tolerance protein
FOB29_RS14650	COG4232	protein-disulfide reductase activity
FOB29_RS14665	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOB29_RS14675	COG1333	cytochrome c biogenesis protein
FOB29_RS14680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB29_RS14695	COG1965	Belongs to the frataxin family
FOB29_RS14705	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOB29_RS14710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOB29_RS14715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOB29_RS14735	COG2814	Major facilitator Superfamily
FOB29_RS14750	COG0367	asparagine synthase
FOB29_RS14780	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB29_RS14790	COG0367	asparagine synthase
FOB29_RS14810	COG0367	asparagine synthase
FOB29_RS14830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB29_RS14835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOB29_RS14885	COG1175	transmembrane transport
FOB29_RS14890	COG3842	ATPase activity
FOB29_RS14895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FOB29_RS14900	COG2186	Transcriptional regulator
FOB29_RS14910	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS14920	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS14930	COG1129	ABC transporter
FOB29_RS14940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOB29_RS14945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS14950	COG1956	GAF domain-containing protein
FOB29_RS14955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB29_RS14960	COG0531	amino acid
FOB29_RS14990	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOB29_RS14995	COG3568	Endonuclease Exonuclease Phosphatase
FOB29_RS15000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB29_RS15010	COG0477	Major facilitator Superfamily
FOB29_RS15045	COG0859	PFAM glycosyl transferase family 9
FOB29_RS15055	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOB29_RS15065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOB29_RS15070	COG1127	ABC transporter
FOB29_RS15090	COG1686	Belongs to the peptidase S11 family
FOB29_RS15100	COG2921	Belongs to the UPF0250 family
FOB29_RS15105	COG0321	lipoyl(octanoyl) transferase activity
FOB29_RS15110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOB29_RS15115	COG2096	Adenosyltransferase
FOB29_RS15125	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOB29_RS15130	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FOB29_RS15140	COG0523	cobalamin synthesis protein
FOB29_RS15145	COG0735	belongs to the Fur family
FOB29_RS15155	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FOB29_RS15180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FOB29_RS15190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOB29_RS15195	COG1560	Kdo2-lipid A biosynthetic process
FOB29_RS15205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOB29_RS15210	COG0583	DNA-binding transcription factor activity
FOB29_RS15225	COG0066	3-isopropylmalate dehydratase activity
FOB29_RS15240	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS15250	COG1950	PFAM Membrane protein of
FOB29_RS15255	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOB29_RS15270	COG3220	belongs to the UPF0276 family
FOB29_RS15290	COG1305	Transglutaminase-like
FOB29_RS15300	COG2308	Evidence 4 Homologs of previously reported genes of
FOB29_RS15305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOB29_RS15325	COG0513	Belongs to the DEAD box helicase family
FOB29_RS15330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FOB29_RS15335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FOB29_RS15350	COG2207	Transcriptional regulator
FOB29_RS15355	COG0735	belongs to the Fur family
FOB29_RS15390	COG0640	Transcriptional regulator
FOB29_RS15425	COG1172	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS15495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FOB29_RS15500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS15505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS15520	COG0758	DNA mediated transformation
FOB29_RS15535	COG1966	Carbon starvation protein
FOB29_RS15540	COG2879	small protein
FOB29_RS15545	COG1522	sequence-specific DNA binding
FOB29_RS15555	COG0242	peptide deformylase activity
FOB29_RS15560	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOB29_RS15570	COG0546	phosphoglycolate phosphatase activity
FOB29_RS15585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB29_RS15590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS15620	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS15625	COG0583	DNA-binding transcription factor activity
FOB29_RS15630	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB29_RS15660	COG2267	carboxylic ester hydrolase activity
FOB29_RS15665	COG2072	flavoprotein involved in K transport
FOB29_RS15670	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS15675	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS15680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FOB29_RS15690	COG0583	DNA-binding transcription factor activity
FOB29_RS15695	COG2814	Major facilitator Superfamily
FOB29_RS15700	COG0583	DNA-binding transcription factor activity
FOB29_RS15710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FOB29_RS15710	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB29_RS15720	COG5000	phosphorelay sensor kinase activity
FOB29_RS15725	COG2204	response regulator
FOB29_RS15730	COG0569	domain protein
FOB29_RS15735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOB29_RS15740	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FOB29_RS15745	COG2226	methyltransferase
FOB29_RS15765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOB29_RS15770	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOB29_RS15775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOB29_RS15785	COG0588	phosphoglycerate mutase activity
FOB29_RS15790	COG4942	peptidase
FOB29_RS15795	COG0793	Belongs to the peptidase S41A family
FOB29_RS15800	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOB29_RS15815	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS15820	COG0861	Integral membrane protein TerC family
FOB29_RS15835	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOB29_RS15840	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB29_RS15840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB29_RS15860	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOB29_RS15865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOB29_RS15870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FOB29_RS15875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOB29_RS15880	COG0142	geranyltranstransferase activity
FOB29_RS15905	COG0154	amidase activity
FOB29_RS15910	COG0683	leucine binding
FOB29_RS15940	COG0659	secondary active sulfate transmembrane transporter activity
FOB29_RS15960	COG1228	amidohydrolase
FOB29_RS15980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOB29_RS15985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOB29_RS15990	COG2890	protein-(glutamine-N5) methyltransferase activity
FOB29_RS15995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOB29_RS16015	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB29_RS16020	COG0288	reversible hydration of carbon dioxide
FOB29_RS16040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FOB29_RS16050	COG4829	muconolactone delta-isomerase
FOB29_RS16055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FOB29_RS16065	COG1414	Transcriptional regulator
FOB29_RS16070	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS16075	COG2031	fatty acid transporter
FOB29_RS16080	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS16085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOB29_RS16090	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOB29_RS16110	COG0129	dihydroxy-acid dehydratase activity
FOB29_RS16115	COG3539	Fimbrial protein
FOB29_RS16125	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
FOB29_RS16145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS16150	COG0583	DNA-binding transcription factor activity
FOB29_RS16155	COG0628	permease
FOB29_RS16160	COG5285	phytanoyl-CoA dioxygenase
FOB29_RS16165	COG1595	DNA-templated transcription, initiation
FOB29_RS16170	COG3712	iron ion homeostasis
FOB29_RS16175	COG4774	siderophore transport
FOB29_RS16180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FOB29_RS16265	COG0436	Aminotransferase
FOB29_RS16275	COG0235	Class ii aldolase
FOB29_RS16290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOB29_RS16295	COG0022	dehydrogenase e1 component
FOB29_RS16300	COG0509	glycine decarboxylation via glycine cleavage system
FOB29_RS16325	COG3284	Transcriptional regulator
FOB29_RS16335	COG1819	glycosyl
FOB29_RS16350	COG1192	Involved in chromosome partitioning
FOB29_RS16365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOB29_RS16400	COG2233	PERMEase
FOB29_RS16405	COG0326	Molecular chaperone. Has ATPase activity
FOB29_RS16410	COG2271	Major facilitator Superfamily
FOB29_RS16415	COG4948	Mandelate Racemase Muconate Lactonizing
FOB29_RS16420	COG0800	Aldolase
FOB29_RS16430	COG1414	Transcriptional regulator
FOB29_RS16440	COG4336	lyase activity
FOB29_RS16470	COG0625	glutathione transferase activity
FOB29_RS16485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOB29_RS16490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOB29_RS16500	COG1178	ABC-type Fe3 transport system permease component
FOB29_RS16505	COG3842	ATPase activity
FOB29_RS16510	COG0583	DNA-binding transcription factor activity
FOB29_RS16515	COG0560	Phosphoserine phosphatase
FOB29_RS16520	COG1652	LysM domain
FOB29_RS16535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOB29_RS16545	COG0583	DNA-binding transcription factor activity
FOB29_RS16550	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS16575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FOB29_RS16580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB29_RS16585	COG0277	FAD linked oxidase domain protein
FOB29_RS16600	COG0582	viral genome integration into host DNA
FOB29_RS16620	COG0492	ferredoxin-NADP+ reductase activity
FOB29_RS16685	COG2207	Transcriptional regulator
FOB29_RS16700	COG0596	Alpha beta hydrolase
FOB29_RS16705	COG0583	DNA-binding transcription factor activity
FOB29_RS16720	COG0583	DNA-binding transcription factor activity
FOB29_RS16725	COG2267	carboxylic ester hydrolase activity
FOB29_RS16730	COG0024	Methionine aminopeptidase
FOB29_RS16745	COG0583	DNA-binding transcription factor activity
FOB29_RS16750	COG0596	Alpha beta hydrolase
FOB29_RS16755	COG2267	carboxylic ester hydrolase activity
FOB29_RS16785	COG2814	Major facilitator Superfamily
FOB29_RS16795	COG0583	DNA-binding transcription factor activity
FOB29_RS16805	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FOB29_RS16805	COG0551	DNA topoisomerase type I activity
FOB29_RS16870	COG3550	peptidyl-serine autophosphorylation
FOB29_RS16890	COG4942	peptidase
FOB29_RS16910	COG3119	arylsulfatase activity
FOB29_RS16935	COG0583	DNA-binding transcription factor activity
FOB29_RS16945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FOB29_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS16955	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS16970	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS16985	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS16995	COG1024	Enoyl-CoA hydratase
FOB29_RS17000	COG3386	PFAM SMP-30 Gluconolaconase
FOB29_RS17005	COG0583	DNA-binding transcription factor activity
FOB29_RS17010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB29_RS17015	COG0426	domain, Protein
FOB29_RS17015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB29_RS17060	COG2072	flavoprotein involved in K transport
FOB29_RS17065	COG0583	DNA-binding transcription factor activity
FOB29_RS17070	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS17075	COG1309	transcriptional regulator
FOB29_RS17110	COG1309	transcriptional regulator
FOB29_RS17115	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS17120	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOB29_RS17140	COG0625	glutathione transferase activity
FOB29_RS17145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOB29_RS17150	COG0583	DNA-binding transcription factor activity
FOB29_RS17160	COG0765	amino acid transport
FOB29_RS17165	COG0765	amino acid transport
FOB29_RS17170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS17190	COG1024	Enoyl-CoA hydratase
FOB29_RS17205	COG0583	DNA-binding transcription factor activity
FOB29_RS17215	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS17220	COG2423	ornithine cyclodeaminase activity
FOB29_RS17240	COG1073	alpha beta
FOB29_RS17240	COG2226	methyltransferase
FOB29_RS17275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS17280	COG2084	Dehydrogenase
FOB29_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS17320	COG1177	transmembrane transport
FOB29_RS17325	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB29_RS17330	COG3842	ATPase activity
FOB29_RS17345	COG0010	Belongs to the arginase family
FOB29_RS17350	COG3539	Fimbrial protein
FOB29_RS17375	COG1054	Belongs to the UPF0176 family
FOB29_RS17380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB29_RS17380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOB29_RS17390	COG0489	protein tyrosine kinase activity
FOB29_RS17405	COG0717	Belongs to the dCTP deaminase family
FOB29_RS17410	COG0456	acetyltransferase
FOB29_RS17410	COG1214	PFAM Peptidase M22, glycoprotease
FOB29_RS17425	COG2081	HI0933 family
FOB29_RS17440	COG0559	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS17465	COG0371	Dehydrogenase
FOB29_RS17475	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOB29_RS17480	COG0509	glycine decarboxylation via glycine cleavage system
FOB29_RS17485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB29_RS17485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOB29_RS17490	COG5339	Protein conserved in bacteria
FOB29_RS17505	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS17510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS17515	COG0601	transmembrane transport
FOB29_RS17520	COG0747	negative chemotaxis
FOB29_RS17535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS17540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS17560	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FOB29_RS17565	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOB29_RS17570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOB29_RS17585	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS17600	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS17605	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS17610	COG0166	Belongs to the GPI family
FOB29_RS17625	COG0277	FAD linked oxidase domain protein
FOB29_RS17630	COG0745	RESPONSE REGULATOR receiver
FOB29_RS17635	COG5000	phosphorelay sensor kinase activity
FOB29_RS17635	COG5002	protein histidine kinase activity
FOB29_RS17640	COG2186	Transcriptional regulator
FOB29_RS17645	COG1368	sulfuric ester hydrolase activity
FOB29_RS17655	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FOB29_RS17670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS17680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOB29_RS17690	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOB29_RS17695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOB29_RS17705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOB29_RS17710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOB29_RS17715	COG0193	aminoacyl-tRNA hydrolase activity
FOB29_RS17725	COG0012	GTP binding
FOB29_RS17745	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOB29_RS17750	COG0732	type I restriction modification DNA specificity domain
FOB29_RS17765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FOB29_RS17795	COG2814	Major facilitator Superfamily
FOB29_RS17800	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS17820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB29_RS17825	COG1024	Enoyl-CoA hydratase
FOB29_RS17830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS17835	COG2188	Transcriptional regulator
FOB29_RS17875	COG3135	benzoate transporter
FOB29_RS17880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOB29_RS17885	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOB29_RS17890	COG0742	ribosomal rna small subunit methyltransferase
FOB29_RS17905	COG3639	organic phosphonate transmembrane transporter activity
FOB29_RS17910	COG3639	organic phosphonate transmembrane transporter activity
FOB29_RS17915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOB29_RS17990	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOB29_RS17995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FOB29_RS18005	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOB29_RS18015	COG0284	orotidine-5'-phosphate decarboxylase activity
FOB29_RS18020	COG1252	NADH dehydrogenase
FOB29_RS18025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOB29_RS18035	COG0459	protein refolding
FOB29_RS18040	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOB29_RS18060	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOB29_RS18065	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS18090	COG1175	transmembrane transport
FOB29_RS18115	COG2226	methyltransferase
FOB29_RS18115	COG1073	alpha beta
FOB29_RS18140	COG0459	protein refolding
FOB29_RS18175	COG3971	2-oxopent-4-enoate hydratase activity
FOB29_RS18185	COG4569	acetaldehyde dehydrogenase (acetylating) activity
FOB29_RS18190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOB29_RS18200	COG0657	acetylesterase activity
FOB29_RS18225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS18240	COG1595	DNA-templated transcription, initiation
FOB29_RS18250	COG4774	siderophore transport
FOB29_RS18265	COG0583	DNA-binding transcription factor activity
FOB29_RS18275	COG1595	DNA-templated transcription, initiation
FOB29_RS18285	COG0513	Belongs to the DEAD box helicase family
FOB29_RS18290	COG1802	Transcriptional regulator
FOB29_RS18295	COG1802	Transcriptional regulator
FOB29_RS18300	COG0028	Belongs to the TPP enzyme family
FOB29_RS18325	COG0683	leucine binding
FOB29_RS18340	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS18350	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS18355	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS18375	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS18385	COG3485	protocatechuate 3,4-dioxygenase
FOB29_RS18390	COG3485	protocatechuate 3,4-dioxygenase
FOB29_RS18395	COG0583	DNA-binding transcription factor activity
FOB29_RS18400	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FOB29_RS18405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FOB29_RS18410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB29_RS18415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FOB29_RS18420	COG1414	Transcriptional regulator
FOB29_RS18425	COG0583	DNA-binding transcription factor activity
FOB29_RS18435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS18440	COG0477	Major facilitator Superfamily
FOB29_RS18445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOB29_RS18470	COG4566	intracellular signal transduction
FOB29_RS18475	COG4191	Histidine kinase
FOB29_RS18475	COG2205	protein histidine kinase activity
FOB29_RS18475	COG0745	RESPONSE REGULATOR receiver
FOB29_RS18485	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS18490	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS18495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS18500	COG0601	transmembrane transport
FOB29_RS18505	COG0747	negative chemotaxis
FOB29_RS18510	COG1802	Transcriptional regulator
FOB29_RS18515	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOB29_RS18545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOB29_RS18560	COG2832	Protein of unknown function (DUF454)
FOB29_RS18580	COG1686	Belongs to the peptidase S11 family
FOB29_RS18590	COG3685	Protein conserved in bacteria
FOB29_RS18600	COG1368	sulfuric ester hydrolase activity
FOB29_RS18605	COG0154	amidase activity
FOB29_RS18615	COG1137	ATPase activity
FOB29_RS18640	COG1024	Enoyl-CoA hydratase
FOB29_RS18650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB29_RS18655	COG1802	Transcriptional regulator
FOB29_RS18660	COG0583	DNA-binding transcription factor activity
FOB29_RS18665	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS18675	COG0601	transmembrane transport
FOB29_RS18680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS18685	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS18690	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS18705	COG0488	(ABC) transporter
FOB29_RS18720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FOB29_RS18725	COG2894	cell division
FOB29_RS18730	COG0850	regulation of cytokinetic process
FOB29_RS18735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOB29_RS18745	COG1294	oxidase, subunit
FOB29_RS18765	COG0514	ATP-dependent DNA helicase (RecQ)
FOB29_RS18770	COG2255	four-way junction helicase activity
FOB29_RS18775	COG0702	epimerase
FOB29_RS18785	COG0632	four-way junction helicase activity
FOB29_RS18790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOB29_RS18810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOB29_RS18820	COG0006	proline dipeptidase activity
FOB29_RS18835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FOB29_RS18855	COG4783	chaperone-mediated protein folding
FOB29_RS18860	COG0429	hydrolase of the alpha beta-hydrolase fold
FOB29_RS18885	COG0513	Belongs to the DEAD box helicase family
FOB29_RS18900	COG1058	Belongs to the CinA family
FOB29_RS18900	COG1546	Belongs to the CinA family
FOB29_RS18905	COG1414	Transcriptional regulator
FOB29_RS18920	COG0167	dihydroorotate dehydrogenase activity
FOB29_RS18925	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOB29_RS18930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOB29_RS18940	COG0583	DNA-binding transcription factor activity
FOB29_RS18975	COG0523	cobalamin synthesis protein
FOB29_RS18980	COG1335	isochorismatase
FOB29_RS18985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FOB29_RS18990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB29_RS18995	COG1802	Transcriptional regulator
FOB29_RS19000	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FOB29_RS19020	COG1280	lysine exporter protein (LysE YggA)
FOB29_RS19025	COG2828	Protein conserved in bacteria
FOB29_RS19055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOB29_RS19080	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FOB29_RS19085	COG0735	belongs to the Fur family
FOB29_RS19090	COG0497	DNA recombination
FOB29_RS19095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOB29_RS19100	COG1420	regulation of RNA biosynthetic process
FOB29_RS19105	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOB29_RS19115	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOB29_RS19125	COG0443	Heat shock 70 kDa protein
FOB29_RS19130	COG0484	heat shock protein binding
FOB29_RS19135	COG0612	Peptidase, M16
FOB29_RS19150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB29_RS19175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB29_RS19190	COG0745	RESPONSE REGULATOR receiver
FOB29_RS19195	COG2205	protein histidine kinase activity
FOB29_RS19200	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FOB29_RS19210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FOB29_RS19225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOB29_RS19235	COG1193	negative regulation of DNA recombination
FOB29_RS19240	COG0492	ferredoxin-NADP+ reductase activity
FOB29_RS19245	COG1674	ftsk spoiiie
FOB29_RS19250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOB29_RS19260	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOB29_RS19265	COG0517	IMP dehydrogenase activity
FOB29_RS19265	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FOB29_RS19285	COG0601	transmembrane transport
FOB29_RS19300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOB29_RS19310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOB29_RS19340	COG2095	MarC family integral membrane protein
FOB29_RS19395	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS19400	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FOB29_RS19405	COG4638	Rieske (2fe-2S)
FOB29_RS19410	COG2186	Transcriptional regulator
FOB29_RS19425	COG1309	transcriptional regulator
FOB29_RS19450	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS19455	COG3022	response to hydroperoxide
FOB29_RS19460	COG1289	transmembrane transporter activity
FOB29_RS19465	COG0028	Belongs to the TPP enzyme family
FOB29_RS19470	COG0440	acetolactate synthase activity
FOB29_RS19475	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOB29_RS19480	COG1183	phosphatidylcholine synthase activity
FOB29_RS19490	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOB29_RS19495	COG1185	polyribonucleotide nucleotidyltransferase activity
FOB29_RS19525	COG0583	DNA-binding transcription factor activity
FOB29_RS19530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOB29_RS19555	COG4221	oxidoreductase activity
FOB29_RS19555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB29_RS19555	COG0604	alcohol dehydrogenase
FOB29_RS19555	COG3321	synthase
FOB29_RS19560	COG0149	triose-phosphate isomerase activity
FOB29_RS19565	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FOB29_RS19570	COG0438	transferase activity, transferring glycosyl groups
FOB29_RS19575	COG4607	ABC-type enterochelin transport system periplasmic component
FOB29_RS19580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOB29_RS19585	COG4605	iron ion homeostasis
FOB29_RS19590	COG4604	ABC transporter, ATP-binding protein
FOB29_RS19610	COG0179	Fumarylacetoacetate (FAA) hydrolase
FOB29_RS19620	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS19635	COG2186	Transcriptional regulator
FOB29_RS19640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS19645	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS19675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS19695	COG1414	Transcriptional regulator
FOB29_RS19700	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FOB29_RS19705	COG2202	Pas domain
FOB29_RS19705	COG2200	EAL domain
FOB29_RS19705	COG2199	diguanylate cyclase activity
FOB29_RS19745	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS19775	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS19785	COG3608	succinylglutamate desuccinylase aspartoacylase
FOB29_RS19785	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOB29_RS19790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOB29_RS19815	COG2020	methyltransferase activity
FOB29_RS19830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOB29_RS19845	COG0251	oxidation-reduction process
FOB29_RS19855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS19865	COG0765	amino acid transport
FOB29_RS19870	COG1126	abc transporter atp-binding protein
FOB29_RS19880	COG1176	ABC-type spermidine putrescine transport system, permease component I
FOB29_RS19885	COG1177	transmembrane transport
FOB29_RS19890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOB29_RS19895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOB29_RS19905	COG4221	oxidoreductase activity
FOB29_RS19905	COG0604	alcohol dehydrogenase
FOB29_RS19905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOB29_RS19905	COG3321	synthase
FOB29_RS19910	COG3842	ATPase activity
FOB29_RS19915	COG2072	flavoprotein involved in K transport
FOB29_RS19925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOB29_RS19935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOB29_RS19965	COG0583	DNA-binding transcription factor activity
FOB29_RS19970	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FOB29_RS19995	COG2321	neutral zinc metallopeptidase
FOB29_RS20000	COG0009	L-threonylcarbamoyladenylate synthase
FOB29_RS20005	COG1994	Peptidase M50
FOB29_RS20010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOB29_RS20015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOB29_RS20025	COG2850	peptidyl-arginine hydroxylation
FOB29_RS20030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOB29_RS20050	COG3360	Dodecin
FOB29_RS20085	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB29_RS20095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB29_RS20120	COG0668	transmembrane transport
FOB29_RS20135	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FOB29_RS20140	COG0483	inositol monophosphate 1-phosphatase activity
FOB29_RS20145	COG1253	flavin adenine dinucleotide binding
FOB29_RS20150	COG1968	undecaprenyl-diphosphatase activity
FOB29_RS20155	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOB29_RS20160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOB29_RS20170	COG0215	cysteine-tRNA ligase activity
FOB29_RS20180	COG0825	malonyl-CoA metabolic process
FOB29_RS20185	COG0037	tRNA processing
FOB29_RS20200	COG1132	(ABC) transporter
FOB29_RS20215	COG2814	Major facilitator Superfamily
FOB29_RS20220	COG4772	TonB-dependent receptor
FOB29_RS20230	COG4993	Dehydrogenase
FOB29_RS20250	COG1414	Transcriptional regulator
FOB29_RS20255	COG1832	CoA-binding protein
FOB29_RS20265	COG0251	oxidation-reduction process
FOB29_RS20290	COG1902	pentaerythritol trinitrate reductase activity
FOB29_RS20300	COG0318	PFAM AMP-dependent synthetase and ligase
FOB29_RS20315	COG0183	Belongs to the thiolase family
FOB29_RS20320	COG1024	Enoyl-CoA hydratase
FOB29_RS20320	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS20325	COG2067	long-chain fatty acid transport protein
FOB29_RS20330	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOB29_RS20330	COG1024	Enoyl-CoA hydratase
FOB29_RS20340	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS20345	COG1309	transcriptional regulator
FOB29_RS20350	COG1045	serine acetyltransferase
FOB29_RS20360	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FOB29_RS20370	COG1012	belongs to the aldehyde dehydrogenase family
FOB29_RS20375	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FOB29_RS20390	COG0210	DNA helicase
FOB29_RS20395	COG0598	Magnesium transport protein CorA
FOB29_RS20405	COG0747	negative chemotaxis
FOB29_RS20410	COG0601	transmembrane transport
FOB29_RS20415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS20420	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS20430	COG0583	DNA-binding transcription factor activity
FOB29_RS20435	COG1380	Effector of murein hydrolase LrgA
FOB29_RS20440	COG1346	cytolysis
FOB29_RS20455	COG0783	Belongs to the Dps family
FOB29_RS20480	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FOB29_RS20490	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOB29_RS20495	COG1845	cytochrome c oxidase, subunit III
FOB29_RS20500	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FOB29_RS20530	COG1666	GTP binding
FOB29_RS20540	COG1129	ABC transporter
FOB29_RS20590	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS20595	COG5006	permease, DMT superfamily
FOB29_RS20615	COG2264	protein methyltransferase activity
FOB29_RS20630	COG3383	formate dehydrogenase (NAD+) activity
FOB29_RS20650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOB29_RS20655	COG0746	molybdenum cofactor guanylyltransferase activity
FOB29_RS20660	COG0303	'Molybdopterin
FOB29_RS20665	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB29_RS20670	COG0314	molybdopterin synthase activity
FOB29_RS20680	COG0315	cyclic pyranopterin monophosphate synthase activity
FOB29_RS20690	COG0412	Dienelactone hydrolase
FOB29_RS20700	COG0678	peroxiredoxin activity
FOB29_RS20715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOB29_RS20725	COG0542	response to heat
FOB29_RS20735	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOB29_RS20745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FOB29_RS20750	COG1477	protein flavinylation
FOB29_RS20775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOB29_RS20780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FOB29_RS20780	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FOB29_RS20785	COG1562	ergosterol biosynthetic process
FOB29_RS20795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOB29_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS20835	COG0254	rRNA binding
FOB29_RS20840	COG3483	tryptophan 2,3-dioxygenase activity
FOB29_RS20845	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FOB29_RS20850	COG2003	Belongs to the UPF0758 family
FOB29_RS20860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOB29_RS20865	COG0625	glutathione transferase activity
FOB29_RS20895	COG0523	cobalamin synthesis protein
FOB29_RS20900	COG0583	DNA-binding transcription factor activity
FOB29_RS20910	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOB29_RS20915	COG1187	pseudouridine synthase activity
FOB29_RS20920	COG0779	Required for maturation of 30S ribosomal subunits
FOB29_RS20925	COG0195	Participates in both transcription termination and antitermination
FOB29_RS20925	COG2251	uridine kinase activity
FOB29_RS20930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOB29_RS20935	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOB29_RS20940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOB29_RS20945	COG1217	gtp-binding protein TYPA
FOB29_RS20965	COG1802	Transcriptional regulator
FOB29_RS20975	COG1024	Enoyl-CoA hydratase
FOB29_RS20980	COG0318	PFAM AMP-dependent synthetase and ligase
FOB29_RS20990	COG2032	superoxide dismutase activity
FOB29_RS20995	COG0667	Aldo Keto reductase
FOB29_RS21005	COG4120	Belongs to the binding-protein-dependent transport system permease family
FOB29_RS21015	COG0725	ABC transporter, periplasmic molybdate-binding protein
FOB29_RS21020	COG4149	molybdate abc transporter
FOB29_RS21025	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FOB29_RS21045	COG0745	RESPONSE REGULATOR receiver
FOB29_RS21050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS21055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOB29_RS21065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOB29_RS21070	COG0736	holo-[acyl-carrier-protein] synthase activity
FOB29_RS21075	COG1472	Belongs to the glycosyl hydrolase 3 family
FOB29_RS21085	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOB29_RS21095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB29_RS21095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOB29_RS21100	COG2224	Isocitrate lyase
FOB29_RS21105	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FOB29_RS21105	COG4106	trans-aconitate 2-methyltransferase activity
FOB29_RS21115	COG0156	8-amino-7-oxononanoate synthase activity
FOB29_RS21120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS21125	COG2217	Heavy metal translocating P-type atpase
FOB29_RS21135	COG3278	Belongs to the heme-copper respiratory oxidase family
FOB29_RS21155	COG0348	domain, Protein
FOB29_RS21170	COG1846	Transcriptional regulator
FOB29_RS21175	COG1764	response to oxidative stress
FOB29_RS21180	COG1131	(ABC) transporter
FOB29_RS21185	COG0842	Transport permease protein
FOB29_RS21190	COG0628	permease
FOB29_RS21200	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FOB29_RS21210	COG2814	Major facilitator Superfamily
FOB29_RS21250	COG0583	DNA-binding transcription factor activity
FOB29_RS21255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FOB29_RS21265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOB29_RS21270	COG0444	Belongs to the ABC transporter superfamily
FOB29_RS21275	COG4608	Belongs to the ABC transporter superfamily
FOB29_RS21295	COG2814	Major facilitator Superfamily
FOB29_RS21305	COG3530	Putative quorum-sensing-regulated virulence factor
FOB29_RS21310	COG0583	DNA-binding transcription factor activity
FOB29_RS21320	COG0494	nUDIX hydrolase
FOB29_RS21330	COG0697	spore germination
FOB29_RS21335	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOB29_RS21385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOB29_RS21390	COG1702	phosphate starvation-inducible protein PhoH
FOB29_RS21395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOB29_RS21400	COG4535	Mg2 and Co2 transporter CorC
FOB29_RS21405	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOB29_RS21410	COG0667	Aldo Keto reductase
FOB29_RS21440	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB29_RS21445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOB29_RS21450	COG1862	Preprotein translocase
FOB29_RS21455	COG0343	queuine tRNA-ribosyltransferase activity
FOB29_RS21460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOB29_RS21465	COG2027	D-alanyl-D-alanine carboxypeptidase
FOB29_RS21470	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FOB29_RS21475	COG1648	precorrin-2 dehydrogenase activity
FOB29_RS21475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOB29_RS21485	COG4575	ribosome binding
FOB29_RS21500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOB29_RS21505	COG0741	lytic transglycosylase activity
FOB29_RS21510	COG0436	Aminotransferase
FOB29_RS21520	COG0281	malic enzyme
FOB29_RS21520	COG0280	phosphate acetyltransferase
FOB29_RS21535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOB29_RS21540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOB29_RS21545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOB29_RS21550	COG0126	phosphoglycerate kinase activity
FOB29_RS21560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FOB29_RS21565	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOB29_RS21585	COG0625	glutathione transferase activity
FOB29_RS21630	COG0306	phosphate transporter
FOB29_RS21635	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOB29_RS21645	COG0739	heme binding
FOB29_RS21655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOB29_RS21660	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FOB29_RS21665	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FOB29_RS21670	COG3639	organic phosphonate transmembrane transporter activity
FOB29_RS21675	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FOB29_RS21685	COG3454	Phosphonate metabolism
FOB29_RS21690	COG2188	Transcriptional regulator
FOB29_RS21695	COG3624	Phosphonate C-P lyase system protein PhnG
FOB29_RS21705	COG3626	phosphonate metabolism
FOB29_RS21710	COG3627	carbon phosphorus lyase activity
FOB29_RS21715	COG4107	phosphonate C-P lyase system protein PhnK
FOB29_RS21720	COG4778	phosphonate C-P lyase system protein PhnL
FOB29_RS21725	COG3454	Phosphonate metabolism
FOB29_RS21760	COG1301	dicarboxylic acid transport
FOB29_RS21770	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOB29_RS21780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOB29_RS21785	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOB29_RS21790	COG0009	L-threonylcarbamoyladenylate synthase
FOB29_RS21795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS21810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOB29_RS21815	COG0765	amino acid transport
FOB29_RS21820	COG1126	abc transporter atp-binding protein
FOB29_RS21825	COG0028	Belongs to the TPP enzyme family
FOB29_RS21835	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS21840	COG0028	Belongs to the TPP enzyme family
FOB29_RS21845	COG0583	DNA-binding transcription factor activity
FOB29_RS21850	COG4974	Belongs to the 'phage' integrase family
FOB29_RS21860	COG0693	protein deglycase activity
FOB29_RS21870	COG1686	Belongs to the peptidase S11 family
FOB29_RS21895	COG1074	ATP-dependent DNA helicase activity
FOB29_RS21905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOB29_RS21910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOB29_RS21915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOB29_RS21920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS21925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOB29_RS21935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOB29_RS21940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FOB29_RS21945	COG0505	Belongs to the CarA family
FOB29_RS21950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOB29_RS21960	COG4221	oxidoreductase activity
FOB29_RS21965	COG0406	alpha-ribazole phosphatase activity
FOB29_RS21995	COG2233	PERMEase
FOB29_RS22000	COG3620	sequence-specific DNA binding
FOB29_RS22005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOB29_RS22015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOB29_RS22020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOB29_RS22030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOB29_RS22065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOB29_RS22075	COG0701	Predicted permease
FOB29_RS22115	COG0372	Belongs to the citrate synthase family
FOB29_RS22120	COG0583	DNA-binding transcription factor activity
FOB29_RS22130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS22135	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS22140	COG1960	acyl-CoA dehydrogenase activity
FOB29_RS22150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOB29_RS22165	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS22170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FOB29_RS22220	COG1024	Enoyl-CoA hydratase
FOB29_RS22235	COG2030	dehydratase
FOB29_RS22245	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS22270	COG3307	-O-antigen
FOB29_RS22280	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS22295	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FOB29_RS22335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOB29_RS22355	COG0003	Pfam Anion-transporting ATPase
FOB29_RS22360	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS22365	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS22370	COG1215	transferase activity, transferring glycosyl groups
FOB29_RS22375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FOB29_RS22380	COG0457	Tetratricopeptide repeat
FOB29_RS22410	COG0583	DNA-binding transcription factor activity
FOB29_RS22415	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS22430	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS22435	COG3246	L-lysine catabolic process to acetate
FOB29_RS22445	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOB29_RS22470	COG4774	siderophore transport
FOB29_RS22475	COG3712	iron ion homeostasis
FOB29_RS22480	COG1595	DNA-templated transcription, initiation
FOB29_RS22485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FOB29_RS22490	COG2146	nitrite reductase [NAD(P)H] activity
FOB29_RS22495	COG0583	DNA-binding transcription factor activity
FOB29_RS22505	COG4638	Rieske (2fe-2S)
FOB29_RS22510	COG2267	carboxylic ester hydrolase activity
FOB29_RS22515	COG4166	transmembrane transport
FOB29_RS22520	COG0601	transmembrane transport
FOB29_RS22530	COG4172	Belongs to the ABC transporter superfamily
FOB29_RS22540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FOB29_RS22550	COG0583	DNA-binding transcription factor activity
FOB29_RS22565	COG3181	Tripartite tricarboxylate transporter family receptor
FOB29_RS22570	COG2188	Transcriptional regulator
FOB29_RS22605	COG0811	peptide transport
FOB29_RS22635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOB29_RS22660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOB29_RS22680	COG0747	negative chemotaxis
FOB29_RS22685	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
FOB29_RS22700	COG1028	Short-chain dehydrogenase reductase Sdr
FOB29_RS22705	COG0500	methyltransferase
FOB29_RS22735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FOB29_RS22765	COG0540	Belongs to the ATCase OTCase family
FOB29_RS22770	COG2974	May be involved in recombination
FOB29_RS22795	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage