locus-tag	class	description
CS347_RS00025	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS00035	COG2030	dehydratase
CS347_RS00050	COG1024	Enoyl-CoA hydratase
CS347_RS00100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS00130	COG1960	acyl-CoA dehydrogenase activity
CS347_RS00135	COG1960	acyl-CoA dehydrogenase activity
CS347_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS00150	COG0583	DNA-binding transcription factor activity
CS347_RS00155	COG0372	Belongs to the citrate synthase family
CS347_RS00195	COG0701	Predicted permease
CS347_RS00205	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CS347_RS00240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CS347_RS00250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS347_RS00255	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CS347_RS00265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CS347_RS00270	COG3620	sequence-specific DNA binding
CS347_RS00275	COG2233	PERMEase
CS347_RS00305	COG0406	alpha-ribazole phosphatase activity
CS347_RS00310	COG4221	oxidoreductase activity
CS347_RS00320	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CS347_RS00325	COG0505	Belongs to the CarA family
CS347_RS00330	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CS347_RS00335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS347_RS00345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS347_RS00350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS00355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CS347_RS00360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CS347_RS00365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CS347_RS00375	COG1074	ATP-dependent DNA helicase activity
CS347_RS00395	COG1686	Belongs to the peptidase S11 family
CS347_RS00405	COG0693	protein deglycase activity
CS347_RS00415	COG4974	Belongs to the 'phage' integrase family
CS347_RS00420	COG0583	DNA-binding transcription factor activity
CS347_RS00425	COG0028	Belongs to the TPP enzyme family
CS347_RS00430	COG1960	acyl-CoA dehydrogenase activity
CS347_RS00440	COG0028	Belongs to the TPP enzyme family
CS347_RS00445	COG1126	abc transporter atp-binding protein
CS347_RS00450	COG0765	amino acid transport
CS347_RS00455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS00470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS00475	COG0009	L-threonylcarbamoyladenylate synthase
CS347_RS00480	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CS347_RS00485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CS347_RS00495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CS347_RS00505	COG1301	dicarboxylic acid transport
CS347_RS00540	COG3454	Phosphonate metabolism
CS347_RS00545	COG4778	phosphonate C-P lyase system protein PhnL
CS347_RS00550	COG4107	phosphonate C-P lyase system protein PhnK
CS347_RS00555	COG3627	carbon phosphorus lyase activity
CS347_RS00560	COG3626	phosphonate metabolism
CS347_RS00570	COG3624	Phosphonate C-P lyase system protein PhnG
CS347_RS00575	COG2188	Transcriptional regulator
CS347_RS00580	COG3454	Phosphonate metabolism
CS347_RS00590	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CS347_RS00595	COG3639	organic phosphonate transmembrane transporter activity
CS347_RS00600	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CS347_RS00605	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS347_RS00610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS347_RS00620	COG0739	heme binding
CS347_RS00630	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS347_RS00635	COG0306	phosphate transporter
CS347_RS00680	COG0625	glutathione transferase activity
CS347_RS00700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CS347_RS00705	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CS347_RS00715	COG0126	phosphoglycerate kinase activity
CS347_RS00720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CS347_RS00725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CS347_RS00730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CS347_RS00745	COG0280	phosphate acetyltransferase
CS347_RS00745	COG0281	malic enzyme
CS347_RS00755	COG0436	Aminotransferase
CS347_RS00760	COG0741	lytic transglycosylase activity
CS347_RS00765	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CS347_RS00780	COG4575	ribosome binding
CS347_RS00790	COG1648	precorrin-2 dehydrogenase activity
CS347_RS00790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CS347_RS00795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CS347_RS00800	COG2027	D-alanyl-D-alanine carboxypeptidase
CS347_RS00805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CS347_RS00810	COG0343	queuine tRNA-ribosyltransferase activity
CS347_RS00815	COG1862	Preprotein translocase
CS347_RS00820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS347_RS00825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS347_RS00855	COG0667	Aldo Keto reductase
CS347_RS00860	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CS347_RS00865	COG4535	Mg2 and Co2 transporter CorC
CS347_RS00870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CS347_RS00875	COG1702	phosphate starvation-inducible protein PhoH
CS347_RS00880	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS347_RS00930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CS347_RS00935	COG0697	spore germination
CS347_RS00945	COG0494	nUDIX hydrolase
CS347_RS00955	COG0583	DNA-binding transcription factor activity
CS347_RS00960	COG3530	Putative quorum-sensing-regulated virulence factor
CS347_RS00970	COG2814	Major facilitator Superfamily
CS347_RS00990	COG4608	Belongs to the ABC transporter superfamily
CS347_RS00995	COG0444	Belongs to the ABC transporter superfamily
CS347_RS01000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS01010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS347_RS01015	COG0583	DNA-binding transcription factor activity
CS347_RS01055	COG2814	Major facilitator Superfamily
CS347_RS01065	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CS347_RS01075	COG0628	permease
CS347_RS01080	COG0842	Transport permease protein
CS347_RS01085	COG1131	(ABC) transporter
CS347_RS01090	COG1764	response to oxidative stress
CS347_RS01095	COG1846	Transcriptional regulator
CS347_RS01110	COG0348	domain, Protein
CS347_RS01130	COG3278	Belongs to the heme-copper respiratory oxidase family
CS347_RS01140	COG2217	Heavy metal translocating P-type atpase
CS347_RS01145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS01150	COG0156	8-amino-7-oxononanoate synthase activity
CS347_RS01160	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CS347_RS01160	COG4106	trans-aconitate 2-methyltransferase activity
CS347_RS01165	COG2224	Isocitrate lyase
CS347_RS01170	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS347_RS01170	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CS347_RS01180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CS347_RS01190	COG1472	Belongs to the glycosyl hydrolase 3 family
CS347_RS01195	COG0736	holo-[acyl-carrier-protein] synthase activity
CS347_RS01200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CS347_RS01210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS347_RS01215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS01220	COG0745	RESPONSE REGULATOR receiver
CS347_RS01240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS347_RS01245	COG4149	molybdate abc transporter
CS347_RS01250	COG0725	ABC transporter, periplasmic molybdate-binding protein
CS347_RS01260	COG4120	Belongs to the binding-protein-dependent transport system permease family
CS347_RS01270	COG0667	Aldo Keto reductase
CS347_RS01275	COG2032	superoxide dismutase activity
CS347_RS01285	COG0318	PFAM AMP-dependent synthetase and ligase
CS347_RS01290	COG1024	Enoyl-CoA hydratase
CS347_RS01300	COG1802	Transcriptional regulator
CS347_RS01320	COG1217	gtp-binding protein TYPA
CS347_RS01325	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CS347_RS01330	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CS347_RS01335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CS347_RS01340	COG2251	uridine kinase activity
CS347_RS01340	COG0195	Participates in both transcription termination and antitermination
CS347_RS01345	COG0779	Required for maturation of 30S ribosomal subunits
CS347_RS01350	COG1187	pseudouridine synthase activity
CS347_RS01355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CS347_RS01365	COG0583	DNA-binding transcription factor activity
CS347_RS01370	COG0523	cobalamin synthesis protein
CS347_RS01400	COG0625	glutathione transferase activity
CS347_RS01405	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CS347_RS01415	COG2003	Belongs to the UPF0758 family
CS347_RS01420	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CS347_RS01425	COG3483	tryptophan 2,3-dioxygenase activity
CS347_RS01430	COG0254	rRNA binding
CS347_RS01465	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS01470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CS347_RS01480	COG1562	ergosterol biosynthetic process
CS347_RS01485	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS347_RS01485	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CS347_RS01490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CS347_RS01515	COG1477	protein flavinylation
CS347_RS01520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CS347_RS01530	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS347_RS01540	COG0542	response to heat
CS347_RS01550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CS347_RS01565	COG0678	peroxiredoxin activity
CS347_RS01575	COG0412	Dienelactone hydrolase
CS347_RS01585	COG0315	cyclic pyranopterin monophosphate synthase activity
CS347_RS01595	COG0314	molybdopterin synthase activity
CS347_RS01600	COG0521	Mo-molybdopterin cofactor biosynthetic process
CS347_RS01605	COG0303	'Molybdopterin
CS347_RS01610	COG0746	molybdenum cofactor guanylyltransferase activity
CS347_RS01615	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CS347_RS01635	COG3383	formate dehydrogenase (NAD+) activity
CS347_RS01650	COG2264	protein methyltransferase activity
CS347_RS01670	COG5006	permease, DMT superfamily
CS347_RS01675	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS01725	COG1129	ABC transporter
CS347_RS01735	COG1666	GTP binding
CS347_RS01765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS347_RS01770	COG1845	cytochrome c oxidase, subunit III
CS347_RS01775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS347_RS01785	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CS347_RS01810	COG0783	Belongs to the Dps family
CS347_RS01825	COG1346	cytolysis
CS347_RS01830	COG1380	Effector of murein hydrolase LrgA
CS347_RS01835	COG0583	DNA-binding transcription factor activity
CS347_RS01845	COG4172	Belongs to the ABC transporter superfamily
CS347_RS01850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS01855	COG0601	transmembrane transport
CS347_RS01860	COG0747	negative chemotaxis
CS347_RS01870	COG0598	Magnesium transport protein CorA
CS347_RS01875	COG0210	DNA helicase
CS347_RS01890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS347_RS01895	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS01905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS347_RS01915	COG1045	serine acetyltransferase
CS347_RS01920	COG1309	transcriptional regulator
CS347_RS01925	COG1960	acyl-CoA dehydrogenase activity
CS347_RS01935	COG1024	Enoyl-CoA hydratase
CS347_RS01935	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS01940	COG2067	long-chain fatty acid transport protein
CS347_RS01945	COG1024	Enoyl-CoA hydratase
CS347_RS01945	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS01950	COG0183	Belongs to the thiolase family
CS347_RS01965	COG0318	PFAM AMP-dependent synthetase and ligase
CS347_RS01975	COG1902	pentaerythritol trinitrate reductase activity
CS347_RS02000	COG0251	oxidation-reduction process
CS347_RS02010	COG1832	CoA-binding protein
CS347_RS02015	COG1414	Transcriptional regulator
CS347_RS02035	COG4993	Dehydrogenase
CS347_RS02045	COG4772	TonB-dependent receptor
CS347_RS02050	COG2814	Major facilitator Superfamily
CS347_RS02065	COG1132	(ABC) transporter
CS347_RS02080	COG0037	tRNA processing
CS347_RS02085	COG0825	malonyl-CoA metabolic process
CS347_RS02095	COG0215	cysteine-tRNA ligase activity
CS347_RS02105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CS347_RS02110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS347_RS02115	COG1968	undecaprenyl-diphosphatase activity
CS347_RS02120	COG1253	flavin adenine dinucleotide binding
CS347_RS02125	COG0483	inositol monophosphate 1-phosphatase activity
CS347_RS02130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CS347_RS02145	COG0668	transmembrane transport
CS347_RS02170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CS347_RS02180	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS347_RS02215	COG3360	Dodecin
CS347_RS02235	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CS347_RS02240	COG2850	peptidyl-arginine hydroxylation
CS347_RS02250	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CS347_RS02255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS347_RS02260	COG1994	Peptidase M50
CS347_RS02265	COG0009	L-threonylcarbamoyladenylate synthase
CS347_RS02270	COG2321	neutral zinc metallopeptidase
CS347_RS02295	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS02300	COG0583	DNA-binding transcription factor activity
CS347_RS02330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS347_RS02340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS347_RS02350	COG2072	flavoprotein involved in K transport
CS347_RS02355	COG3842	ATPase activity
CS347_RS02360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS347_RS02360	COG3321	synthase
CS347_RS02360	COG0604	alcohol dehydrogenase
CS347_RS02360	COG4221	oxidoreductase activity
CS347_RS02370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS347_RS02375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS347_RS02380	COG1177	transmembrane transport
CS347_RS02385	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS347_RS02395	COG1126	abc transporter atp-binding protein
CS347_RS02400	COG0765	amino acid transport
CS347_RS02410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS02420	COG0251	oxidation-reduction process
CS347_RS02435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS347_RS02450	COG2020	methyltransferase activity
CS347_RS02475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CS347_RS02480	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CS347_RS02480	COG3608	succinylglutamate desuccinylase aspartoacylase
CS347_RS02490	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS02520	COG4172	Belongs to the ABC transporter superfamily
CS347_RS02560	COG2200	EAL domain
CS347_RS02560	COG2199	diguanylate cyclase activity
CS347_RS02560	COG2202	Pas domain
CS347_RS02565	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CS347_RS02570	COG1414	Transcriptional regulator
CS347_RS02590	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS02620	COG1960	acyl-CoA dehydrogenase activity
CS347_RS02625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS02630	COG2186	Transcriptional regulator
CS347_RS02645	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS02655	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS347_RS02675	COG4604	ABC transporter, ATP-binding protein
CS347_RS02680	COG4605	iron ion homeostasis
CS347_RS02685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS347_RS02690	COG4607	ABC-type enterochelin transport system periplasmic component
CS347_RS02695	COG0438	transferase activity, transferring glycosyl groups
CS347_RS02700	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS347_RS02705	COG0149	triose-phosphate isomerase activity
CS347_RS02710	COG3321	synthase
CS347_RS02710	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS347_RS02710	COG4221	oxidoreductase activity
CS347_RS02710	COG0604	alcohol dehydrogenase
CS347_RS02735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS347_RS02740	COG0583	DNA-binding transcription factor activity
CS347_RS02770	COG1185	polyribonucleotide nucleotidyltransferase activity
CS347_RS02775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CS347_RS02785	COG1183	phosphatidylcholine synthase activity
CS347_RS02790	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CS347_RS02795	COG0440	acetolactate synthase activity
CS347_RS02800	COG0028	Belongs to the TPP enzyme family
CS347_RS02805	COG1289	transmembrane transporter activity
CS347_RS02810	COG3022	response to hydroperoxide
CS347_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS02840	COG1309	transcriptional regulator
CS347_RS02855	COG2186	Transcriptional regulator
CS347_RS02860	COG4638	Rieske (2fe-2S)
CS347_RS02865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CS347_RS02870	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS02925	COG2095	MarC family integral membrane protein
CS347_RS02955	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CS347_RS02965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CS347_RS02980	COG0601	transmembrane transport
CS347_RS03000	COG0517	IMP dehydrogenase activity
CS347_RS03000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CS347_RS03005	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS347_RS03015	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CS347_RS03020	COG1674	ftsk spoiiie
CS347_RS03025	COG0492	ferredoxin-NADP+ reductase activity
CS347_RS03030	COG1193	negative regulation of DNA recombination
CS347_RS03040	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CS347_RS03055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CS347_RS03065	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CS347_RS03070	COG2205	protein histidine kinase activity
CS347_RS03075	COG0745	RESPONSE REGULATOR receiver
CS347_RS03090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS347_RS03115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CS347_RS03130	COG0612	Peptidase, M16
CS347_RS03135	COG0484	heat shock protein binding
CS347_RS03140	COG0443	Heat shock 70 kDa protein
CS347_RS03150	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CS347_RS03160	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CS347_RS03165	COG1420	regulation of RNA biosynthetic process
CS347_RS03170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CS347_RS03175	COG0497	DNA recombination
CS347_RS03180	COG0735	belongs to the Fur family
CS347_RS03185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS347_RS03210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS347_RS03240	COG2828	Protein conserved in bacteria
CS347_RS03245	COG1280	lysine exporter protein (LysE YggA)
CS347_RS03265	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CS347_RS03270	COG1802	Transcriptional regulator
CS347_RS03275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS347_RS03280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CS347_RS03285	COG1335	isochorismatase
CS347_RS03290	COG0523	cobalamin synthesis protein
CS347_RS03325	COG0583	DNA-binding transcription factor activity
CS347_RS03335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CS347_RS03340	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CS347_RS03345	COG0167	dihydroorotate dehydrogenase activity
CS347_RS03360	COG1414	Transcriptional regulator
CS347_RS03365	COG1546	Belongs to the CinA family
CS347_RS03365	COG1058	Belongs to the CinA family
CS347_RS03380	COG0513	Belongs to the DEAD box helicase family
CS347_RS03405	COG0429	hydrolase of the alpha beta-hydrolase fold
CS347_RS03410	COG4783	chaperone-mediated protein folding
CS347_RS03430	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CS347_RS03445	COG0006	proline dipeptidase activity
CS347_RS03455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS03475	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CS347_RS03480	COG0632	four-way junction helicase activity
CS347_RS03490	COG0702	epimerase
CS347_RS03495	COG2255	four-way junction helicase activity
CS347_RS03500	COG0514	ATP-dependent DNA helicase (RecQ)
CS347_RS03520	COG1294	oxidase, subunit
CS347_RS03530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS347_RS03535	COG0850	regulation of cytokinetic process
CS347_RS03540	COG2894	cell division
CS347_RS03545	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CS347_RS03560	COG0488	(ABC) transporter
CS347_RS03575	COG4608	Belongs to the ABC transporter superfamily
CS347_RS03580	COG0444	Belongs to the ABC transporter superfamily
CS347_RS03585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS03590	COG0601	transmembrane transport
CS347_RS03600	COG1215	transferase activity, transferring glycosyl groups
CS347_RS03605	COG0583	DNA-binding transcription factor activity
CS347_RS03610	COG1802	Transcriptional regulator
CS347_RS03615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS347_RS03625	COG1024	Enoyl-CoA hydratase
CS347_RS03650	COG1137	ATPase activity
CS347_RS03660	COG0154	amidase activity
CS347_RS03665	COG1368	sulfuric ester hydrolase activity
CS347_RS03675	COG3685	Protein conserved in bacteria
CS347_RS03685	COG1686	Belongs to the peptidase S11 family
CS347_RS03705	COG2832	Protein of unknown function (DUF454)
CS347_RS03720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS347_RS03750	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CS347_RS03755	COG1802	Transcriptional regulator
CS347_RS03760	COG0747	negative chemotaxis
CS347_RS03765	COG0601	transmembrane transport
CS347_RS03770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS03775	COG0444	Belongs to the ABC transporter superfamily
CS347_RS03780	COG4608	Belongs to the ABC transporter superfamily
CS347_RS03790	COG2205	protein histidine kinase activity
CS347_RS03790	COG0745	RESPONSE REGULATOR receiver
CS347_RS03790	COG4191	Histidine kinase
CS347_RS03795	COG4566	intracellular signal transduction
CS347_RS03820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS347_RS03825	COG0477	Major facilitator Superfamily
CS347_RS03830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS03840	COG0583	DNA-binding transcription factor activity
CS347_RS03845	COG1414	Transcriptional regulator
CS347_RS03850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS03855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS347_RS03860	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS347_RS03865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS347_RS03870	COG0583	DNA-binding transcription factor activity
CS347_RS03875	COG3485	protocatechuate 3,4-dioxygenase
CS347_RS03880	COG3485	protocatechuate 3,4-dioxygenase
CS347_RS03890	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS03910	COG1960	acyl-CoA dehydrogenase activity
CS347_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS03940	COG0683	leucine binding
CS347_RS03965	COG0028	Belongs to the TPP enzyme family
CS347_RS03970	COG1802	Transcriptional regulator
CS347_RS03975	COG1802	Transcriptional regulator
CS347_RS03980	COG0513	Belongs to the DEAD box helicase family
CS347_RS03990	COG1595	DNA-templated transcription, initiation
CS347_RS04000	COG0583	DNA-binding transcription factor activity
CS347_RS04015	COG4774	siderophore transport
CS347_RS04025	COG1595	DNA-templated transcription, initiation
CS347_RS04040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS04065	COG0657	acetylesterase activity
CS347_RS04075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS347_RS04080	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CS347_RS04090	COG3971	2-oxopent-4-enoate hydratase activity
CS347_RS04125	COG0459	protein refolding
CS347_RS04150	COG1073	alpha beta
CS347_RS04150	COG2226	methyltransferase
CS347_RS04175	COG1175	transmembrane transport
CS347_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS04205	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CS347_RS04225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CS347_RS04230	COG0459	protein refolding
CS347_RS04240	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CS347_RS04245	COG1252	NADH dehydrogenase
CS347_RS04250	COG0284	orotidine-5'-phosphate decarboxylase activity
CS347_RS04260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CS347_RS04270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS347_RS04275	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CS347_RS04350	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CS347_RS04355	COG3639	organic phosphonate transmembrane transporter activity
CS347_RS04360	COG3639	organic phosphonate transmembrane transporter activity
CS347_RS04375	COG0742	ribosomal rna small subunit methyltransferase
CS347_RS04380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CS347_RS04385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CS347_RS04390	COG3135	benzoate transporter
CS347_RS04430	COG2188	Transcriptional regulator
CS347_RS04435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS04440	COG1024	Enoyl-CoA hydratase
CS347_RS04445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS347_RS04465	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS04470	COG2814	Major facilitator Superfamily
CS347_RS04500	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CS347_RS04515	COG0732	type I restriction modification DNA specificity domain
CS347_RS04520	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CS347_RS04595	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CS347_RS04600	COG1205	dead DEAH box helicase
CS347_RS04600	COG1111	helicase
CS347_RS04610	COG0582	viral genome integration into host DNA
CS347_RS04615	COG0012	GTP binding
CS347_RS04625	COG0193	aminoacyl-tRNA hydrolase activity
CS347_RS04630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CS347_RS04635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CS347_RS04645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CS347_RS04650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CS347_RS04660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CS347_RS04670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS04685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CS347_RS04695	COG1368	sulfuric ester hydrolase activity
CS347_RS04700	COG2186	Transcriptional regulator
CS347_RS04705	COG5000	phosphorelay sensor kinase activity
CS347_RS04705	COG5002	protein histidine kinase activity
CS347_RS04710	COG0745	RESPONSE REGULATOR receiver
CS347_RS04715	COG0277	FAD linked oxidase domain protein
CS347_RS04730	COG0166	Belongs to the GPI family
CS347_RS04735	COG0438	transferase activity, transferring glycosyl groups
CS347_RS04740	COG0438	transferase activity, transferring glycosyl groups
CS347_RS04755	COG0438	transferase activity, transferring glycosyl groups
CS347_RS04770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS347_RS04775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS347_RS04780	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CS347_RS04800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS04805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS04820	COG0747	negative chemotaxis
CS347_RS04825	COG0601	transmembrane transport
CS347_RS04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS04835	COG4172	Belongs to the ABC transporter superfamily
CS347_RS04850	COG5339	Protein conserved in bacteria
CS347_RS04855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS347_RS04855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CS347_RS04860	COG0509	glycine decarboxylation via glycine cleavage system
CS347_RS04865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CS347_RS04875	COG0371	Dehydrogenase
CS347_RS04900	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS347_RS04915	COG2081	HI0933 family
CS347_RS04930	COG0456	acetyltransferase
CS347_RS04930	COG1214	PFAM Peptidase M22, glycoprotease
CS347_RS04935	COG0717	Belongs to the dCTP deaminase family
CS347_RS04950	COG0489	protein tyrosine kinase activity
CS347_RS04960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS347_RS04960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS347_RS04965	COG1054	Belongs to the UPF0176 family
CS347_RS04990	COG3539	Fimbrial protein
CS347_RS04995	COG0010	Belongs to the arginase family
CS347_RS05010	COG3842	ATPase activity
CS347_RS05015	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS347_RS05020	COG1177	transmembrane transport
CS347_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS05060	COG2084	Dehydrogenase
CS347_RS05065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS05100	COG1073	alpha beta
CS347_RS05100	COG2226	methyltransferase
CS347_RS05120	COG2423	ornithine cyclodeaminase activity
CS347_RS05125	COG1960	acyl-CoA dehydrogenase activity
CS347_RS05135	COG0583	DNA-binding transcription factor activity
CS347_RS05150	COG1024	Enoyl-CoA hydratase
CS347_RS05170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS05175	COG0765	amino acid transport
CS347_RS05180	COG0765	amino acid transport
CS347_RS05190	COG0583	DNA-binding transcription factor activity
CS347_RS05195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CS347_RS05200	COG0625	glutathione transferase activity
CS347_RS05220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CS347_RS05225	COG1960	acyl-CoA dehydrogenase activity
CS347_RS05230	COG1309	transcriptional regulator
CS347_RS05265	COG1309	transcriptional regulator
CS347_RS05270	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS05275	COG0583	DNA-binding transcription factor activity
CS347_RS05280	COG2072	flavoprotein involved in K transport
CS347_RS05325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS347_RS05325	COG0426	domain, Protein
CS347_RS05330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS347_RS05335	COG0583	DNA-binding transcription factor activity
CS347_RS05340	COG3386	PFAM SMP-30 Gluconolaconase
CS347_RS05345	COG1024	Enoyl-CoA hydratase
CS347_RS05355	COG1960	acyl-CoA dehydrogenase activity
CS347_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS05385	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS05390	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS05395	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS347_RS05405	COG0583	DNA-binding transcription factor activity
CS347_RS05430	COG3119	arylsulfatase activity
CS347_RS05450	COG4942	peptidase
CS347_RS05470	COG3550	peptidyl-serine autophosphorylation
CS347_RS05535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CS347_RS05535	COG0551	DNA topoisomerase type I activity
CS347_RS05545	COG0583	DNA-binding transcription factor activity
CS347_RS05555	COG2814	Major facilitator Superfamily
CS347_RS05585	COG2267	carboxylic ester hydrolase activity
CS347_RS05590	COG0596	Alpha beta hydrolase
CS347_RS05595	COG0583	DNA-binding transcription factor activity
CS347_RS05610	COG0024	Methionine aminopeptidase
CS347_RS05620	COG2267	carboxylic ester hydrolase activity
CS347_RS05625	COG0583	DNA-binding transcription factor activity
CS347_RS05640	COG0583	DNA-binding transcription factor activity
CS347_RS05645	COG0596	Alpha beta hydrolase
CS347_RS05660	COG2207	Transcriptional regulator
CS347_RS05725	COG0492	ferredoxin-NADP+ reductase activity
CS347_RS05745	COG0582	viral genome integration into host DNA
CS347_RS05760	COG0277	FAD linked oxidase domain protein
CS347_RS05765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS347_RS05770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS347_RS05795	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS05800	COG0583	DNA-binding transcription factor activity
CS347_RS05810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CS347_RS05825	COG1652	LysM domain
CS347_RS05830	COG0560	Phosphoserine phosphatase
CS347_RS05835	COG0583	DNA-binding transcription factor activity
CS347_RS05840	COG3842	ATPase activity
CS347_RS05845	COG1178	ABC-type Fe3 transport system permease component
CS347_RS05855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CS347_RS05860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS347_RS05875	COG0625	glutathione transferase activity
CS347_RS05905	COG4336	lyase activity
CS347_RS05915	COG1414	Transcriptional regulator
CS347_RS05925	COG0800	Aldolase
CS347_RS05930	COG4948	Mandelate Racemase Muconate Lactonizing
CS347_RS05935	COG2271	Major facilitator Superfamily
CS347_RS05940	COG0326	Molecular chaperone. Has ATPase activity
CS347_RS05945	COG2233	PERMEase
CS347_RS05980	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS347_RS05995	COG1192	Involved in chromosome partitioning
CS347_RS06010	COG1819	glycosyl
CS347_RS06020	COG3284	Transcriptional regulator
CS347_RS06045	COG0509	glycine decarboxylation via glycine cleavage system
CS347_RS06050	COG0022	dehydrogenase e1 component
CS347_RS06055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CS347_RS06070	COG0235	Class ii aldolase
CS347_RS06080	COG0436	Aminotransferase
CS347_RS06165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS347_RS06170	COG4774	siderophore transport
CS347_RS06175	COG3712	iron ion homeostasis
CS347_RS06180	COG1595	DNA-templated transcription, initiation
CS347_RS06185	COG5285	phytanoyl-CoA dioxygenase
CS347_RS06190	COG0628	permease
CS347_RS06195	COG0583	DNA-binding transcription factor activity
CS347_RS06200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS06220	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CS347_RS06230	COG3539	Fimbrial protein
CS347_RS06235	COG0129	dihydroxy-acid dehydratase activity
CS347_RS06255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CS347_RS06260	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CS347_RS06265	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS06270	COG2031	fatty acid transporter
CS347_RS06275	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS06280	COG1414	Transcriptional regulator
CS347_RS06290	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CS347_RS06295	COG4829	muconolactone delta-isomerase
CS347_RS06305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS347_RS06325	COG0288	reversible hydration of carbon dioxide
CS347_RS06330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS347_RS06350	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CS347_RS06355	COG2890	protein-(glutamine-N5) methyltransferase activity
CS347_RS06360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CS347_RS06365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CS347_RS06385	COG1228	amidohydrolase
CS347_RS06405	COG0659	secondary active sulfate transmembrane transporter activity
CS347_RS06435	COG0683	leucine binding
CS347_RS06440	COG0154	amidase activity
CS347_RS06465	COG0142	geranyltranstransferase activity
CS347_RS06470	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CS347_RS06475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CS347_RS06480	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CS347_RS06485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CS347_RS06505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS347_RS06505	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CS347_RS06510	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CS347_RS06525	COG0861	Integral membrane protein TerC family
CS347_RS06530	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS06545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CS347_RS06550	COG0793	Belongs to the peptidase S41A family
CS347_RS06555	COG4942	peptidase
CS347_RS06560	COG0588	phosphoglycerate mutase activity
CS347_RS06570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS347_RS06575	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CS347_RS06580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CS347_RS06600	COG2226	methyltransferase
CS347_RS06605	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CS347_RS06610	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CS347_RS06615	COG0569	domain protein
CS347_RS06620	COG2204	response regulator
CS347_RS06625	COG5000	phosphorelay sensor kinase activity
CS347_RS06635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS347_RS06635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS347_RS06645	COG0583	DNA-binding transcription factor activity
CS347_RS06650	COG2814	Major facilitator Superfamily
CS347_RS06655	COG0583	DNA-binding transcription factor activity
CS347_RS06665	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS347_RS06670	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS06675	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS06680	COG2072	flavoprotein involved in K transport
CS347_RS06685	COG2267	carboxylic ester hydrolase activity
CS347_RS06715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CS347_RS06720	COG0583	DNA-binding transcription factor activity
CS347_RS06725	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS06755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS06760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS347_RS06775	COG0546	phosphoglycolate phosphatase activity
CS347_RS06785	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS347_RS06790	COG0242	peptide deformylase activity
CS347_RS06800	COG1522	sequence-specific DNA binding
CS347_RS06805	COG2879	small protein
CS347_RS06810	COG1966	Carbon starvation protein
CS347_RS06825	COG0758	DNA mediated transformation
CS347_RS06840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS06845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS06850	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CS347_RS06920	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS347_RS06955	COG0640	Transcriptional regulator
CS347_RS06990	COG0735	belongs to the Fur family
CS347_RS06995	COG2207	Transcriptional regulator
CS347_RS07010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS347_RS07015	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CS347_RS07020	COG0513	Belongs to the DEAD box helicase family
CS347_RS07040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CS347_RS07045	COG2308	Evidence 4 Homologs of previously reported genes of
CS347_RS07055	COG1305	Transglutaminase-like
CS347_RS07075	COG3220	belongs to the UPF0276 family
CS347_RS07090	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CS347_RS07095	COG1950	PFAM Membrane protein of
CS347_RS07105	COG0438	transferase activity, transferring glycosyl groups
CS347_RS07120	COG0066	3-isopropylmalate dehydratase activity
CS347_RS07135	COG0583	DNA-binding transcription factor activity
CS347_RS07140	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CS347_RS07150	COG1560	Kdo2-lipid A biosynthetic process
CS347_RS07155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CS347_RS07165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CS347_RS07190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CS347_RS07200	COG0735	belongs to the Fur family
CS347_RS07205	COG0523	cobalamin synthesis protein
CS347_RS07215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CS347_RS07220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CS347_RS07230	COG2096	Adenosyltransferase
CS347_RS07235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CS347_RS07240	COG0321	lipoyl(octanoyl) transferase activity
CS347_RS07245	COG2921	Belongs to the UPF0250 family
CS347_RS07255	COG1686	Belongs to the peptidase S11 family
CS347_RS07275	COG1127	ABC transporter
CS347_RS07280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS347_RS07290	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CS347_RS07300	COG0859	PFAM glycosyl transferase family 9
CS347_RS07335	COG0477	Major facilitator Superfamily
CS347_RS07345	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS347_RS07350	COG3568	Endonuclease Exonuclease Phosphatase
CS347_RS07355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CS347_RS07385	COG0531	amino acid
CS347_RS07390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS347_RS07395	COG1956	GAF domain-containing protein
CS347_RS07400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS07405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CS347_RS07415	COG1129	ABC transporter
CS347_RS07425	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS347_RS07435	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS347_RS07445	COG2186	Transcriptional regulator
CS347_RS07450	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CS347_RS07455	COG3842	ATPase activity
CS347_RS07460	COG1175	transmembrane transport
CS347_RS07510	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CS347_RS07515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS347_RS07535	COG0367	asparagine synthase
CS347_RS07555	COG0367	asparagine synthase
CS347_RS07565	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CS347_RS07595	COG0367	asparagine synthase
CS347_RS07610	COG2814	Major facilitator Superfamily
CS347_RS07630	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CS347_RS07635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CS347_RS07640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CS347_RS07650	COG1965	Belongs to the frataxin family
CS347_RS07665	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CS347_RS07670	COG1333	cytochrome c biogenesis protein
CS347_RS07680	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CS347_RS07695	COG4232	protein-disulfide reductase activity
CS347_RS07700	COG1324	tolerance protein
CS347_RS07710	COG0203	ribosomal protein L17
CS347_RS07715	COG0202	RNA polymerase activity
CS347_RS07720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CS347_RS07725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CS347_RS07730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CS347_RS07735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CS347_RS07740	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CS347_RS07745	COG0201	protein transport
CS347_RS07750	COG0200	Binds to the 23S rRNA
CS347_RS07755	COG1841	ribosomal large subunit assembly
CS347_RS07760	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CS347_RS07765	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CS347_RS07770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CS347_RS07775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CS347_RS07780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CS347_RS07785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CS347_RS07790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CS347_RS07795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CS347_RS07820	COG2267	carboxylic ester hydrolase activity
CS347_RS07835	COG1131	(ABC) transporter
CS347_RS07850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CS347_RS07855	COG0255	Belongs to the universal ribosomal protein uL29 family
CS347_RS07860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CS347_RS07865	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CS347_RS07870	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CS347_RS07875	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CS347_RS07880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CS347_RS07885	COG0089	rRNA binding
CS347_RS07890	COG0088	Forms part of the polypeptide exit tunnel
CS347_RS07895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CS347_RS07900	COG0051	transcription antitermination factor activity, RNA binding
CS347_RS07905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS347_RS07910	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS347_RS07915	COG0049	tRNA binding
CS347_RS07920	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CS347_RS07955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CS347_RS07960	COG0085	RNA polymerase activity
CS347_RS07965	COG0222	ribosome binding
CS347_RS07970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CS347_RS07975	COG0081	regulation of translation
CS347_RS07980	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CS347_RS07990	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CS347_RS08000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CS347_RS08020	COG0252	asparaginase activity
CS347_RS08025	COG1475	DNA binding
CS347_RS08030	COG1192	Involved in chromosome partitioning
CS347_RS08035	COG0357	Ribosomal RNA small subunit methyltransferase G
CS347_RS08040	COG0445	tRNA wobble uridine modification
CS347_RS08045	COG1278	Cold shock
CS347_RS08050	COG0436	Aminotransferase
CS347_RS08065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS347_RS08070	COG0583	DNA-binding transcription factor activity
CS347_RS08105	COG0280	phosphate acetyltransferase
CS347_RS08105	COG0281	malic enzyme
CS347_RS08120	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS08125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS08135	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS347_RS08145	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CS347_RS08155	COG1505	serine-type exopeptidase activity
CS347_RS08160	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CS347_RS08170	COG0601	transmembrane transport
CS347_RS08175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS08180	COG0444	Belongs to the ABC transporter superfamily
CS347_RS08185	COG4608	Belongs to the ABC transporter superfamily
CS347_RS08190	COG1473	amidohydrolase
CS347_RS08195	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CS347_RS08200	COG0706	membrane insertase activity
CS347_RS08205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CS347_RS08210	COG0594	ribonuclease P activity
CS347_RS08215	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CS347_RS08220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CS347_RS08225	COG0592	DNA-directed DNA polymerase activity
CS347_RS08240	COG1309	transcriptional regulator
CS347_RS08245	COG1254	Belongs to the acylphosphatase family
CS347_RS08250	COG1304	FMN binding
CS347_RS08255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CS347_RS08270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS08275	COG1960	acyl-CoA dehydrogenase activity
CS347_RS08300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS08310	COG0625	glutathione transferase activity
CS347_RS08315	COG0402	S-adenosylhomocysteine deaminase activity
CS347_RS08320	COG1079	Belongs to the binding-protein-dependent transport system permease family
CS347_RS08325	COG4603	Belongs to the binding-protein-dependent transport system permease family
CS347_RS08330	COG3845	ABC transporter
CS347_RS08345	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS347_RS08350	COG2910	NAD(P)H-binding
CS347_RS08370	COG0702	epimerase
CS347_RS08380	COG3781	membrane
CS347_RS08385	COG1522	sequence-specific DNA binding
CS347_RS08390	COG0028	Belongs to the TPP enzyme family
CS347_RS08400	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS08405	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS08410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS347_RS08415	COG3842	ATPase activity
CS347_RS08435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS347_RS08440	COG2922	Belongs to the Smg family
CS347_RS08445	COG1629	transport
CS347_RS08455	COG2358	TRAP transporter, solute receptor (TAXI family
CS347_RS08465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS347_RS08480	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CS347_RS08485	COG0183	Belongs to the thiolase family
CS347_RS08490	COG1960	acyl-CoA dehydrogenase activity
CS347_RS08495	COG1473	amidohydrolase
CS347_RS08525	COG2200	EAL domain
CS347_RS08530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CS347_RS08540	COG0018	arginyl-trna synthetase
CS347_RS08555	COG0395	ABC-type sugar transport system, permease component
CS347_RS08560	COG1175	transmembrane transport
CS347_RS08565	COG1653	transport
CS347_RS08570	COG3842	ATPase activity
CS347_RS08575	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS347_RS08580	COG3842	ATPase activity
CS347_RS08605	COG0154	amidase activity
CS347_RS08610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS347_RS08620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS347_RS08630	COG0583	DNA-binding transcription factor activity
CS347_RS08650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CS347_RS08655	COG1280	lysine exporter protein (LysE YggA)
CS347_RS08660	COG0513	Belongs to the DEAD box helicase family
CS347_RS08670	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CS347_RS08680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS08685	COG0601	transmembrane transport
CS347_RS08695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CS347_RS08715	COG0697	spore germination
CS347_RS08730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CS347_RS08740	COG2969	positive regulation of protein catabolic process
CS347_RS08745	COG0625	glutathione transferase activity
CS347_RS08750	COG2857	Cytochrome c1
CS347_RS08755	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CS347_RS08760	COG0723	plastoquinol--plastocyanin reductase activity
CS347_RS08765	COG1970	mechanosensitive ion channel activity
CS347_RS08770	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CS347_RS08775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS347_RS08785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS347_RS08790	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CS347_RS08795	COG0537	adenosine 5'-monophosphoramidase activity
CS347_RS08800	COG0140	phosphoribosyl-ATP diphosphatase activity
CS347_RS08805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CS347_RS08810	COG0107	imidazoleglycerol-phosphate synthase activity
CS347_RS08815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CS347_RS08825	COG0131	Imidazoleglycerol-phosphate dehydratase
CS347_RS08830	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS347_RS08835	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CS347_RS08840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CS347_RS08845	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS347_RS08850	COG0271	Belongs to the BolA IbaG family
CS347_RS08855	COG0842	Transport permease protein
CS347_RS08860	COG1131	(ABC) transporter
CS347_RS08875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CS347_RS08880	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CS347_RS08885	COG1127	ABC transporter
CS347_RS08890	COG3047	cAMP biosynthetic process
CS347_RS08900	COG0067	glutamate synthase
CS347_RS08900	COG0069	glutamate synthase activity
CS347_RS08900	COG0070	glutamate synthase
CS347_RS08915	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CS347_RS08930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CS347_RS08935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CS347_RS08945	COG1609	Transcriptional regulator
CS347_RS08950	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CS347_RS08960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS347_RS09000	COG0109	protoheme IX farnesyltransferase activity
CS347_RS09005	COG1999	signal sequence binding
CS347_RS09025	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CS347_RS09030	COG2814	Major facilitator Superfamily
CS347_RS09045	COG1522	sequence-specific DNA binding
CS347_RS09140	COG2124	cytochrome p450
CS347_RS09175	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS347_RS09185	COG1902	pentaerythritol trinitrate reductase activity
CS347_RS09260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CS347_RS09270	COG1671	Belongs to the UPF0178 family
CS347_RS09275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS09300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CS347_RS09305	COG0443	Heat shock 70 kDa protein
CS347_RS09315	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS09340	COG2169	Transcriptional regulator
CS347_RS09340	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CS347_RS09345	COG3145	DNA-N1-methyladenine dioxygenase activity
CS347_RS09355	COG0583	DNA-binding transcription factor activity
CS347_RS09365	COG1473	amidohydrolase
CS347_RS09370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CS347_RS09375	COG1335	isochorismatase
CS347_RS09385	COG1683	Conserved Protein
CS347_RS09390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS09405	COG1120	ATPase activity
CS347_RS09410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CS347_RS09415	COG4558	Periplasmic binding protein
CS347_RS09420	COG3720	iron ion transport
CS347_RS09430	COG3712	iron ion homeostasis
CS347_RS09435	COG1595	DNA-templated transcription, initiation
CS347_RS09465	COG1607	acyl-coa hydrolase
CS347_RS09475	COG0243	molybdopterin cofactor binding
CS347_RS09475	COG3383	formate dehydrogenase (NAD+) activity
CS347_RS09480	COG3383	formate dehydrogenase (NAD+) activity
CS347_RS09480	COG0243	molybdopterin cofactor binding
CS347_RS09485	COG0437	4 iron, 4 sulfur cluster binding
CS347_RS09490	COG2864	formate dehydrogenase
CS347_RS09505	COG3276	selenocysteine insertion sequence binding
CS347_RS09525	COG0583	DNA-binding transcription factor activity
CS347_RS09535	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS09545	COG0134	indole-3-glycerol-phosphate synthase activity
CS347_RS09550	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CS347_RS09555	COG0512	Glutamine amidotransferase of anthranilate synthase
CS347_RS09565	COG0546	phosphoglycolate phosphatase activity
CS347_RS09570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CS347_RS09575	COG2967	ApaG domain
CS347_RS09580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CS347_RS09585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS09590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CS347_RS09600	COG0037	tRNA processing
CS347_RS09620	COG1024	Enoyl-CoA hydratase
CS347_RS09635	COG0356	it plays a direct role in the translocation of protons across the membrane
CS347_RS09645	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CS347_RS09650	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CS347_RS09655	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CS347_RS09660	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CS347_RS09665	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CS347_RS09670	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CS347_RS09680	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CS347_RS09685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CS347_RS09690	COG0210	DNA helicase
CS347_RS09705	COG4608	Belongs to the ABC transporter superfamily
CS347_RS09710	COG0444	Belongs to the ABC transporter superfamily
CS347_RS09715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS09720	COG0601	transmembrane transport
CS347_RS09730	COG0747	negative chemotaxis
CS347_RS09740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CS347_RS09745	COG1024	Enoyl-CoA hydratase
CS347_RS09750	COG1024	Enoyl-CoA hydratase
CS347_RS09755	COG2070	2-Nitropropane dioxygenase
CS347_RS09760	COG1309	transcriptional regulator
CS347_RS09765	COG1960	acyl-CoA dehydrogenase activity
CS347_RS09775	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS09780	COG3245	cytochrome
CS347_RS09805	COG2918	glutathione biosynthetic process
CS347_RS09825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS347_RS09830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS347_RS09835	COG2813	Specifically methylates the guanine in position
CS347_RS09835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CS347_RS09840	COG2223	nitrite transmembrane transporter activity
CS347_RS09845	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS09855	COG2860	membrane
CS347_RS09860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS347_RS09865	COG0708	Exodeoxyribonuclease III
CS347_RS09870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CS347_RS09875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS347_RS09880	COG0154	amidase activity
CS347_RS09885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CS347_RS09890	COG1077	Cell shape determining protein MreB Mrl
CS347_RS09895	COG1792	Involved in formation and maintenance of cell shape
CS347_RS09905	COG0768	penicillin binding
CS347_RS09910	COG0772	Belongs to the SEDS family
CS347_RS09915	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CS347_RS09920	COG0471	metal ion transport
CS347_RS09925	COG1309	transcriptional regulator
CS347_RS09935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS347_RS09950	COG2823	Periplasmic or secreted lipoprotein
CS347_RS09955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CS347_RS09960	COG0792	nuclease activity
CS347_RS09980	COG1660	Displays ATPase and GTPase activities
CS347_RS09995	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CS347_RS10005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CS347_RS10010	COG1137	ATPase activity
CS347_RS10025	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CS347_RS10035	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CS347_RS10050	COG1294	oxidase, subunit
CS347_RS10060	COG4988	ABC transporter
CS347_RS10065	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CS347_RS10070	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CS347_RS10085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS10090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CS347_RS10095	COG1238	metal cluster binding
CS347_RS10105	COG1802	Transcriptional regulator
CS347_RS10115	COG1984	allophanate hydrolase subunit 2
CS347_RS10120	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CS347_RS10135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS347_RS10150	COG2132	Multicopper oxidase
CS347_RS10160	COG5002	protein histidine kinase activity
CS347_RS10170	COG5002	protein histidine kinase activity
CS347_RS10175	COG0745	RESPONSE REGULATOR receiver
CS347_RS10180	COG2226	methyltransferase
CS347_RS10195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS347_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS10235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS347_RS10270	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS347_RS10285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CS347_RS10295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CS347_RS10300	COG1538	Outer membrane efflux protein
CS347_RS10305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CS347_RS10310	COG0351	phosphomethylpyrimidine kinase
CS347_RS10315	COG2022	thiamine diphosphate biosynthetic process
CS347_RS10320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CS347_RS10325	COG4206	TonB-dependent receptor
CS347_RS10335	COG2226	methyltransferase
CS347_RS10350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS347_RS10365	COG1194	a g-specific adenine glycosylase
CS347_RS10375	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CS347_RS10380	COG2177	Part of the ABC transporter FtsEX involved in
CS347_RS10385	COG2884	Cell division ATP-binding protein ftsE
CS347_RS10390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS10395	COG4597	amino acid ABC transporter
CS347_RS10400	COG0765	amino acid transport
CS347_RS10405	COG1126	abc transporter atp-binding protein
CS347_RS10425	COG0477	Major facilitator Superfamily
CS347_RS10435	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CS347_RS10440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CS347_RS10455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CS347_RS10460	COG0237	dephospho-CoA kinase activity
CS347_RS10465	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CS347_RS10490	COG3539	Fimbrial protein
CS347_RS10495	COG2816	NAD+ diphosphatase activity
CS347_RS10505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CS347_RS10540	COG0411	ABC transporter
CS347_RS10575	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS10580	COG1024	Enoyl-CoA hydratase
CS347_RS10610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CS347_RS10615	COG0352	thiamine-phosphate diphosphorylase activity
CS347_RS10630	COG1678	Uncharacterized ACR, COG1678
CS347_RS10635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CS347_RS10660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS347_RS10670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CS347_RS10675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CS347_RS10685	COG0557	exoribonuclease II activity
CS347_RS10690	COG3150	esterase
CS347_RS10695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS347_RS10705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS347_RS10710	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CS347_RS10715	COG0511	ligase activity, forming carbon-carbon bonds
CS347_RS10720	COG0439	Biotin carboxylase
CS347_RS10725	COG2264	protein methyltransferase activity
CS347_RS10735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CS347_RS10760	COG1696	Membrane protein involved in D-alanine export
CS347_RS10765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CS347_RS10795	COG1522	sequence-specific DNA binding
CS347_RS10805	COG2814	Major facilitator Superfamily
CS347_RS10810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CS347_RS10815	COG0045	succinate-CoA ligase (ADP-forming) activity
CS347_RS10815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS347_RS10815	COG0045	succinate-CoA ligase (ADP-forming) activity
CS347_RS10815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS347_RS10815	COG1042	CoA-binding domain protein
CS347_RS10815	COG1042	CoA-binding domain protein
CS347_RS10865	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CS347_RS10890	COG3028	Belongs to the UPF0307 family
CS347_RS10895	COG0312	modulator of DNA gyrase
CS347_RS10905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS347_RS10910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CS347_RS10915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS347_RS10920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CS347_RS10930	COG0316	Belongs to the HesB IscA family
CS347_RS10935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CS347_RS10945	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CS347_RS10955	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CS347_RS10960	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CS347_RS10970	COG1335	isochorismatase
CS347_RS10975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS347_RS10975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CS347_RS10985	COG2766	serine protein kinase
CS347_RS10990	COG2718	Belongs to the UPF0229 family
CS347_RS10995	COG2719	SpoVR family
CS347_RS11015	COG4948	Mandelate Racemase Muconate Lactonizing
CS347_RS11030	COG0477	Major facilitator Superfamily
CS347_RS11040	COG0583	DNA-binding transcription factor activity
CS347_RS11055	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS347_RS11060	COG0251	oxidation-reduction process
CS347_RS11065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CS347_RS11070	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CS347_RS11085	COG0165	Argininosuccinate lyase
CS347_RS11095	COG3707	response regulator
CS347_RS11105	COG0515	serine threonine protein kinase
CS347_RS11110	COG2116	formate transmembrane transporter activity
CS347_RS11120	COG2146	nitrite reductase [NAD(P)H] activity
CS347_RS11120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CS347_RS11125	COG0589	response to stress
CS347_RS11140	COG2816	NAD+ diphosphatase activity
CS347_RS11145	COG1280	lysine exporter protein (LysE YggA)
CS347_RS11185	COG2979	Protein of unknown function (DUF533)
CS347_RS11195	COG1388	LysM domain
CS347_RS11195	COG0741	lytic transglycosylase activity
CS347_RS11200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CS347_RS11205	COG2226	methyltransferase
CS347_RS11210	COG0328	RNA-DNA hybrid ribonuclease activity
CS347_RS11220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS347_RS11225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS347_RS11235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS11240	COG1129	ABC transporter
CS347_RS11240	COG0842	Transport permease protein
CS347_RS11245	COG0842	Transport permease protein
CS347_RS11265	COG0463	Glycosyl transferase, family 2
CS347_RS11270	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CS347_RS11285	COG1073	alpha beta
CS347_RS11295	COG0697	spore germination
CS347_RS11300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS11315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CS347_RS11325	COG1522	sequence-specific DNA binding
CS347_RS11350	COG0823	Involved in the tonB-independent uptake of proteins
CS347_RS11360	COG0848	biopolymer transport protein
CS347_RS11365	COG0811	peptide transport
CS347_RS11370	COG0824	Thioesterase
CS347_RS11375	COG0442	prolyl-tRNA aminoacylation
CS347_RS11405	COG1414	Transcriptional regulator
CS347_RS11410	COG1024	Enoyl-CoA hydratase
CS347_RS11425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CS347_RS11430	COG2084	Dehydrogenase
CS347_RS11435	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS11440	COG1309	transcriptional regulator
CS347_RS11475	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CS347_RS11480	COG4654	Cytochrome c, class I
CS347_RS11485	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS347_RS11535	COG1473	amidohydrolase
CS347_RS11540	COG0418	dihydroorotase activity
CS347_RS11545	COG0488	(ABC) transporter
CS347_RS11555	COG2001	Belongs to the MraZ family
CS347_RS11560	COG0275	rRNA processing
CS347_RS11565	COG3116	cell division
CS347_RS11575	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS347_RS11580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CS347_RS11585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CS347_RS11595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CS347_RS11600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CS347_RS11605	COG1181	Belongs to the D-alanine--D-alanine ligase family
CS347_RS11610	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CS347_RS11625	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CS347_RS11640	COG0739	heme binding
CS347_RS11645	COG0653	protein targeting
CS347_RS11670	COG1522	sequence-specific DNA binding
CS347_RS11685	COG2239	Acts as a magnesium transporter
CS347_RS11695	COG2855	membrane
CS347_RS11700	COG0583	DNA-binding transcription factor activity
CS347_RS11705	COG1473	amidohydrolase
CS347_RS11710	COG0318	PFAM AMP-dependent synthetase and ligase
CS347_RS11720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS347_RS11720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CS347_RS11725	COG1501	Belongs to the glycosyl hydrolase 31 family
CS347_RS11730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CS347_RS11735	COG2011	ABC-type metal ion transport system permease component
CS347_RS11750	COG0300	oxidoreductase activity
CS347_RS11770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CS347_RS11775	COG0156	8-amino-7-oxononanoate synthase activity
CS347_RS11780	COG0604	alcohol dehydrogenase
CS347_RS11780	COG3321	synthase
CS347_RS11780	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS11785	COG0402	S-adenosylhomocysteine deaminase activity
CS347_RS11810	COG0727	PFAM Uncharacterised protein family (UPF0153)
CS347_RS11815	COG2818	Glycosylase
CS347_RS11820	COG2982	Protein involved in outer membrane biogenesis
CS347_RS11850	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CS347_RS11855	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS347_RS11895	COG1215	transferase activity, transferring glycosyl groups
CS347_RS11910	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS347_RS11925	COG0410	ABC transporter
CS347_RS11945	COG0583	DNA-binding transcription factor activity
CS347_RS11950	COG0737	Belongs to the 5'-nucleotidase family
CS347_RS11960	COG4106	trans-aconitate 2-methyltransferase activity
CS347_RS11965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CS347_RS11975	COG0667	Aldo Keto reductase
CS347_RS11990	COG2154	pterin-4-alpha-carbinolamine dehydratase
CS347_RS12000	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CS347_RS12010	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CS347_RS12015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS347_RS12020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CS347_RS12030	COG1929	Belongs to the glycerate kinase type-1 family
CS347_RS12035	COG0469	pyruvate kinase activity
CS347_RS12040	COG0700	Nucleoside recognition
CS347_RS12045	COG1960	acyl-CoA dehydrogenase activity
CS347_RS12050	COG0242	peptide deformylase activity
CS347_RS12070	COG1053	succinate dehydrogenase
CS347_RS12070	COG3976	FMN-binding domain protein
CS347_RS12075	COG0583	DNA-binding transcription factor activity
CS347_RS12085	COG0204	Acyl-transferase
CS347_RS12090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS347_RS12095	COG0751	glycine-tRNA ligase activity
CS347_RS12100	COG0752	glycyl-tRNA synthetase alpha subunit
CS347_RS12105	COG1024	Enoyl-CoA hydratase
CS347_RS12115	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CS347_RS12145	COG0617	tRNA 3'-terminal CCA addition
CS347_RS12160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CS347_RS12165	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CS347_RS12170	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CS347_RS12175	COG0586	Pfam SNARE associated Golgi protein
CS347_RS12180	COG3064	Membrane
CS347_RS12180	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS347_RS12180	COG3210	domain, Protein
CS347_RS12180	COG3210	domain, Protein
CS347_RS12180	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS347_RS12180	COG3064	Membrane
CS347_RS12185	COG0860	N-Acetylmuramoyl-L-alanine amidase
CS347_RS12195	COG0114	fumarate hydratase activity
CS347_RS12205	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS12215	COG0405	Gamma-glutamyltransferase
CS347_RS12225	COG3210	domain, Protein
CS347_RS12235	COG0579	oxidoreductase
CS347_RS12240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS347_RS12245	COG0259	pyridoxamine-phosphate oxidase activity
CS347_RS12260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS12265	COG1136	(ABC) transporter
CS347_RS12265	COG0577	efflux transmembrane transporter activity
CS347_RS12270	COG1538	Outer membrane efflux protein
CS347_RS12275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CS347_RS12285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CS347_RS12310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CS347_RS12335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS12400	COG0583	DNA-binding transcription factor activity
CS347_RS12430	COG0427	acetyl-CoA hydrolase
CS347_RS12435	COG1960	acyl-CoA dehydrogenase activity
CS347_RS12440	COG2301	Belongs to the HpcH HpaI aldolase family
CS347_RS12470	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS347_RS12475	COG0683	leucine binding
CS347_RS12485	COG2205	protein histidine kinase activity
CS347_RS12490	COG3210	domain, Protein
CS347_RS12500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS12505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CS347_RS12510	COG1538	Outer membrane efflux protein
CS347_RS12530	COG3258	Cytochrome c
CS347_RS12535	COG2863	cytochrome
CS347_RS12555	COG2205	protein histidine kinase activity
CS347_RS12570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS12575	COG2301	Belongs to the HpcH HpaI aldolase family
CS347_RS12590	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS12600	COG2814	Major facilitator Superfamily
CS347_RS12615	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS12620	COG4948	Mandelate Racemase Muconate Lactonizing
CS347_RS12625	COG0583	DNA-binding transcription factor activity
CS347_RS12670	COG3585	molybdate ion transport
CS347_RS12675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS347_RS12685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS347_RS12690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS347_RS12705	COG2188	Transcriptional regulator
CS347_RS12710	COG0179	Fumarylacetoacetate (FAA) hydrolase
CS347_RS12720	COG0402	S-adenosylhomocysteine deaminase activity
CS347_RS12725	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CS347_RS12730	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS347_RS12730	COG0022	dehydrogenase e1 component
CS347_RS12735	COG1024	Enoyl-CoA hydratase
CS347_RS12740	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS347_RS12750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS347_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS12785	COG0411	ABC transporter
CS347_RS12810	COG1309	transcriptional regulator
CS347_RS12825	COG1024	Enoyl-CoA hydratase
CS347_RS12845	COG4133	protoheme IX ABC transporter activity
CS347_RS12850	COG0154	amidase activity
CS347_RS12860	COG0583	DNA-binding transcription factor activity
CS347_RS12880	COG2197	response regulator
CS347_RS12885	COG2814	Major facilitator Superfamily
CS347_RS12895	COG4774	siderophore transport
CS347_RS12900	COG3712	iron ion homeostasis
CS347_RS12905	COG1595	DNA-templated transcription, initiation
CS347_RS12950	COG0625	glutathione transferase activity
CS347_RS12960	COG0747	negative chemotaxis
CS347_RS12965	COG0583	DNA-binding transcription factor activity
CS347_RS13000	COG0444	Belongs to the ABC transporter superfamily
CS347_RS13005	COG4608	Belongs to the ABC transporter superfamily
CS347_RS13010	COG2207	Transcriptional regulator
CS347_RS13015	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS13035	COG3284	Transcriptional regulator
CS347_RS13045	COG2814	Major facilitator Superfamily
CS347_RS13050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS347_RS13060	COG1959	2 iron, 2 sulfur cluster binding
CS347_RS13070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS347_RS13075	COG1971	Probably functions as a manganese efflux pump
CS347_RS13090	COG1360	Flagellar Motor Protein
CS347_RS13105	COG0840	transmembrane signaling receptor activity
CS347_RS13125	COG5265	(ABC) transporter
CS347_RS13140	COG0833	amino acid
CS347_RS13170	COG0235	Class ii aldolase
CS347_RS13180	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CS347_RS13185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS13190	COG2186	Transcriptional regulator
CS347_RS13195	COG1024	Enoyl-CoA hydratase
CS347_RS13210	COG0583	DNA-binding transcription factor activity
CS347_RS13220	COG2159	amidohydrolase
CS347_RS13235	COG1301	dicarboxylic acid transport
CS347_RS13245	COG0148	phosphopyruvate hydratase activity
CS347_RS13255	COG2814	Major facilitator Superfamily
CS347_RS13260	COG0583	DNA-binding transcription factor activity
CS347_RS13305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CS347_RS13315	COG4774	siderophore transport
CS347_RS13325	COG3128	pkhd-type hydroxylase
CS347_RS13340	COG3064	Membrane
CS347_RS13345	COG1408	metallophosphoesterase
CS347_RS13355	COG0456	acetyltransferase
CS347_RS13365	COG2610	gluconate transmembrane transporter activity
CS347_RS13375	COG2070	2-Nitropropane dioxygenase
CS347_RS13385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CS347_RS13430	COG1846	Transcriptional regulator
CS347_RS13445	COG5001	Diguanylate cyclase
CS347_RS13445	COG3300	MHYT domain
CS347_RS13475	COG4964	Belongs to the GSP D family
CS347_RS13530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS13535	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CS347_RS13550	COG3384	dioxygenase
CS347_RS13555	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS347_RS13575	COG2176	DNA-directed DNA polymerase activity
CS347_RS13600	COG4221	oxidoreductase activity
CS347_RS13610	COG1511	domain protein
CS347_RS13610	COG3264	Mechanosensitive ion channel
CS347_RS13615	COG0583	DNA-binding transcription factor activity
CS347_RS13620	COG0427	acetyl-CoA hydrolase
CS347_RS13625	COG0583	DNA-binding transcription factor activity
CS347_RS13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS13690	COG0154	amidase activity
CS347_RS13705	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CS347_RS13720	COG0495	leucyl-tRNA aminoacylation
CS347_RS13725	COG2814	Major facilitator Superfamily
CS347_RS13730	COG1846	Transcriptional regulator
CS347_RS13750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CS347_RS13755	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CS347_RS13760	COG2814	Major facilitator Superfamily
CS347_RS13765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CS347_RS13775	COG4176	ABC-type proline glycine betaine transport system permease component
CS347_RS13790	COG0183	Belongs to the thiolase family
CS347_RS13810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS347_RS13810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CS347_RS13820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CS347_RS13825	COG1845	cytochrome c oxidase, subunit III
CS347_RS13830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CS347_RS13835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CS347_RS13840	COG0477	Major facilitator Superfamily
CS347_RS13845	COG0428	transporter
CS347_RS13850	COG0412	Dienelactone hydrolase
CS347_RS13855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS347_RS13860	COG1283	sodium-dependent phosphate transmembrane transporter activity
CS347_RS13865	COG1760	l-serine dehydratase
CS347_RS13870	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CS347_RS13875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CS347_RS13885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CS347_RS13910	COG2311	Membrane
CS347_RS13920	COG2358	TRAP transporter, solute receptor (TAXI family
CS347_RS13925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS13940	COG0456	acetyltransferase
CS347_RS13950	COG0662	Cupin 2, conserved barrel domain protein
CS347_RS13955	COG5285	phytanoyl-CoA dioxygenase
CS347_RS13960	COG0633	Ferredoxin
CS347_RS13960	COG3217	Mosc domain protein beta barrel domain protein
CS347_RS13965	COG2076	Multidrug Resistance protein
CS347_RS13970	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CS347_RS13975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS347_RS13975	COG0543	2 iron, 2 sulfur cluster binding
CS347_RS13980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS347_RS14030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CS347_RS14035	COG0425	Belongs to the sulfur carrier protein TusA family
CS347_RS14045	COG0228	four-way junction DNA binding
CS347_RS14050	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CS347_RS14055	COG0336	Belongs to the RNA methyltransferase TrmD family
CS347_RS14060	COG0525	valine-tRNA ligase activity
CS347_RS14065	COG0105	UTP biosynthetic process
CS347_RS14070	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CS347_RS14085	COG0124	histidyl-tRNA synthetase
CS347_RS14090	COG2976	Protein conserved in bacteria
CS347_RS14095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS347_RS14100	COG1160	GTP binding
CS347_RS14105	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS347_RS14110	COG1923	regulation of RNA biosynthetic process
CS347_RS14115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CS347_RS14120	COG0330	HflC and HflK could
CS347_RS14125	COG0330	HflC and HflK could
CS347_RS14130	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CS347_RS14135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CS347_RS14145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CS347_RS14165	COG0582	viral genome integration into host DNA
CS347_RS14225	COG2207	Transcriptional regulator
CS347_RS14235	COG0475	glutathione-regulated potassium exporter activity
CS347_RS14235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CS347_RS14255	COG0330	HflC and HflK could
CS347_RS14270	COG0840	transmembrane signaling receptor activity
CS347_RS14295	COG2201	protein-glutamate methylesterase activity
CS347_RS14300	COG4251	negative regulation of phosphorylation
CS347_RS14300	COG3706	GGDEF domain
CS347_RS14300	COG5001	Diguanylate cyclase
CS347_RS14300	COG2203	Gaf domain
CS347_RS14305	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CS347_RS14340	COG0583	DNA-binding transcription factor activity
CS347_RS14355	COG2084	Dehydrogenase
CS347_RS14365	COG1803	Methylglyoxal synthase
CS347_RS14365	COG1597	lipid kinase activity
CS347_RS14375	COG0671	phosphoesterase, PA-phosphatase related
CS347_RS14395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS14400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS347_RS14405	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS347_RS14410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS347_RS14415	COG0649	NAD binding
CS347_RS14420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CS347_RS14430	COG1034	ATP synthesis coupled electron transport
CS347_RS14435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CS347_RS14440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CS347_RS14450	COG0713	ATP synthesis coupled electron transport
CS347_RS14465	COG1007	ATP synthesis coupled electron transport
CS347_RS14475	COG0560	Phosphoserine phosphatase
CS347_RS14480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CS347_RS14485	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CS347_RS14490	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CS347_RS14495	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS14500	COG0450	alkyl hydroperoxide reductase
CS347_RS14515	COG1214	PFAM Peptidase M22, glycoprotease
CS347_RS14520	COG1573	uracil-dna glycosylase
CS347_RS14525	COG0477	Major facilitator Superfamily
CS347_RS14530	COG1196	nuclear chromosome segregation
CS347_RS14540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CS347_RS14550	COG0765	amino acid transport
CS347_RS14555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS14565	COG0625	glutathione transferase activity
CS347_RS14570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS347_RS14575	COG0271	Belongs to the BolA IbaG family
CS347_RS14580	COG2917	probably involved in intracellular septation
CS347_RS14585	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CS347_RS14590	COG1122	ATPase activity
CS347_RS14595	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CS347_RS14600	COG1268	BioY protein
CS347_RS14630	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CS347_RS14660	COG0411	ABC transporter
CS347_RS14665	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CS347_RS14670	COG2878	Part of a membrane complex involved in electron transport
CS347_RS14695	COG0251	oxidation-reduction process
CS347_RS14705	COG3228	Belongs to the MtfA family
CS347_RS14710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS347_RS14730	COG0159	tryptophan synthase activity
CS347_RS14735	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CS347_RS14740	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CS347_RS14745	COG1530	ribonuclease E activity
CS347_RS14750	COG0564	pseudouridine synthase activity
CS347_RS14755	COG0546	phosphoglycolate phosphatase activity
CS347_RS14760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CS347_RS14765	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CS347_RS14770	COG3023	N-Acetylmuramoyl-L-alanine amidase
CS347_RS14780	COG0424	maF-like protein
CS347_RS14785	COG1399	metal-binding, possibly nucleic acid-binding protein
CS347_RS14790	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CS347_RS14800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CS347_RS14810	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS14815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CS347_RS14820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CS347_RS14845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CS347_RS14850	COG0481	GTPase activity
CS347_RS14855	COG0681	Belongs to the peptidase S26 family
CS347_RS14860	COG0571	ribonuclease III activity
CS347_RS14865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CS347_RS14870	COG1381	Involved in DNA repair and RecF pathway recombination
CS347_RS14890	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CS347_RS14900	COG0583	DNA-binding transcription factor activity
CS347_RS14915	COG0583	DNA-binding transcription factor activity
CS347_RS14925	COG0791	NLP P60 protein
CS347_RS14930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS347_RS14935	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CS347_RS14945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS347_RS14955	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CS347_RS14995	COG1446	asparaginase
CS347_RS15000	COG4172	Belongs to the ABC transporter superfamily
CS347_RS15005	COG0747	negative chemotaxis
CS347_RS15010	COG0601	transmembrane transport
CS347_RS15015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS15035	COG0504	CTP synthase activity
CS347_RS15045	COG0148	phosphopyruvate hydratase activity
CS347_RS15060	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CS347_RS15070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS347_RS15075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS347_RS15095	COG1981	membrane
CS347_RS15115	COG0039	L-malate dehydrogenase activity
CS347_RS15120	COG2188	Transcriptional regulator
CS347_RS15125	COG2009	succinate dehydrogenase
CS347_RS15130	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CS347_RS15135	COG1053	succinate dehydrogenase
CS347_RS15140	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CS347_RS15145	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CS347_RS15150	COG0372	Belongs to the citrate synthase family
CS347_RS15155	COG0583	DNA-binding transcription factor activity
CS347_RS15160	COG3842	ATPase activity
CS347_RS15170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CS347_RS15175	COG1840	ABC-type Fe3 transport system, periplasmic component
CS347_RS15200	COG3128	pkhd-type hydroxylase
CS347_RS15205	COG4774	siderophore transport
CS347_RS15210	COG0280	phosphate acetyltransferase
CS347_RS15210	COG0281	malic enzyme
CS347_RS15220	COG1297	OPT oligopeptide transporter protein
CS347_RS15225	COG0567	Dehydrogenase, E1 component
CS347_RS15230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS347_RS15235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS347_RS15240	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CS347_RS15265	COG2183	response to ionizing radiation
CS347_RS15270	COG1199	ATP-dependent helicase activity
CS347_RS15310	COG0564	pseudouridine synthase activity
CS347_RS15320	COG3243	poly(R)-hydroxyalkanoic acid synthase
CS347_RS15325	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS15330	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CS347_RS15345	COG0672	)-iron permease
CS347_RS15360	COG2823	Periplasmic or secreted lipoprotein
CS347_RS15370	COG3237	CsbD-like
CS347_RS15375	COG3038	cytochrome b561
CS347_RS15380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS347_RS15380	COG0189	ligase activity
CS347_RS15385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CS347_RS15385	COG0189	ligase activity
CS347_RS15390	COG1132	(ABC) transporter
CS347_RS15400	COG0297	glycogen (starch) synthase activity
CS347_RS15405	COG2833	Protein of unknown function (DUF455)
CS347_RS15410	COG2951	lytic endotransglycosylase activity
CS347_RS15420	COG0589	response to stress
CS347_RS15430	COG3706	GGDEF domain
CS347_RS15495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CS347_RS15510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CS347_RS15515	COG0077	Prephenate dehydratase
CS347_RS15515	COG1605	Chorismate mutase
CS347_RS15520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CS347_RS15525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CS347_RS15530	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CS347_RS15535	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CS347_RS15555	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CS347_RS15560	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CS347_RS15565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CS347_RS15570	COG0587	DNA-directed DNA polymerase activity
CS347_RS15580	COG2951	lytic endotransglycosylase activity
CS347_RS15585	COG0123	including yeast histone deacetylase and acetoin utilization protein
CS347_RS15600	COG2985	domain, Protein
CS347_RS15605	COG1960	acyl-CoA dehydrogenase activity
CS347_RS15610	COG0450	alkyl hydroperoxide reductase
CS347_RS15615	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CS347_RS15620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CS347_RS15625	COG4208	sulfate ABC transporter
CS347_RS15630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CS347_RS15635	COG0175	sulfate reduction
CS347_RS15645	COG2895	sulfate adenylyltransferase (ATP) activity
CS347_RS15665	COG0335	large ribosomal subunit rRNA binding
CS347_RS15670	COG0494	nUDIX hydrolase
CS347_RS15675	COG3622	Belongs to the hyi family
CS347_RS15680	COG1162	GTPase activity
CS347_RS15685	COG0501	Belongs to the peptidase M48B family
CS347_RS15690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CS347_RS15695	COG1335	isochorismatase
CS347_RS15705	COG0583	DNA-binding transcription factor activity
CS347_RS15720	COG3396	Phenylacetate-CoA oxygenase
CS347_RS15725	COG3460	Phenylacetate-CoA oxygenase
CS347_RS15730	COG3396	Phenylacetate-CoA oxygenase
CS347_RS15735	COG2151	metal-sulfur cluster biosynthetic enzyme
CS347_RS15740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CS347_RS15745	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS15750	COG1024	Enoyl-CoA hydratase
CS347_RS15755	COG2050	protein possibly involved in aromatic compounds catabolism
CS347_RS15775	COG1126	abc transporter atp-binding protein
CS347_RS15800	COG2198	Histidine kinase
CS347_RS15800	COG0784	Response regulator, receiver
CS347_RS15800	COG5002	protein histidine kinase activity
CS347_RS15805	COG3437	response regulator, receiver
CS347_RS15820	COG1802	Transcriptional regulator
CS347_RS15825	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS347_RS15825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS347_RS15835	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS15840	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CS347_RS15850	COG3642	lipopolysaccharide core region biosynthetic process
CS347_RS15860	COG3842	ATPase activity
CS347_RS15865	COG1176	ABC-type spermidine putrescine transport system, permease component I
CS347_RS15870	COG1177	transmembrane transport
CS347_RS15875	COG1393	Belongs to the ArsC family
CS347_RS15880	COG2094	Belongs to the DNA glycosylase MPG family
CS347_RS15890	COG1322	Protein conserved in bacteria
CS347_RS15895	COG1960	acyl-CoA dehydrogenase activity
CS347_RS15900	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CS347_RS15905	COG0704	Plays a role in the regulation of phosphate uptake
CS347_RS15910	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CS347_RS15915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CS347_RS15915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CS347_RS15920	COG1643	Atp-dependent helicase
CS347_RS15935	COG0438	transferase activity, transferring glycosyl groups
CS347_RS15940	COG0726	polysaccharide deacetylase
CS347_RS15980	COG1132	(ABC) transporter
CS347_RS15990	COG1530	ribonuclease E activity
CS347_RS16020	COG0583	DNA-binding transcription factor activity
CS347_RS16030	COG0477	Major facilitator Superfamily
CS347_RS16035	COG0500	methyltransferase
CS347_RS16040	COG1418	mRNA catabolic process
CS347_RS16065	COG2204	response regulator
CS347_RS16070	COG4191	Histidine kinase
CS347_RS16075	COG1301	dicarboxylic acid transport
CS347_RS16080	COG0424	maF-like protein
CS347_RS16085	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CS347_RS16090	COG0799	negative regulation of ribosome biogenesis
CS347_RS16095	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CS347_RS16105	COG0151	Belongs to the GarS family
CS347_RS16110	COG0217	transcriptional regulatory protein
CS347_RS16115	COG0433	COG0433 Predicted ATPase
CS347_RS16120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS16125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS347_RS16130	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS16155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CS347_RS16160	COG4172	Belongs to the ABC transporter superfamily
CS347_RS16165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS16170	COG0601	transmembrane transport
CS347_RS16175	COG0747	negative chemotaxis
CS347_RS16185	COG0473	3-isopropylmalate dehydrogenase activity
CS347_RS16190	COG2814	Major facilitator Superfamily
CS347_RS16195	COG1566	PFAM secretion protein HlyD family protein
CS347_RS16205	COG1846	Transcriptional regulator
CS347_RS16225	COG0501	Belongs to the peptidase M48B family
CS347_RS16265	COG1722	exodeoxyribonuclease VII activity
CS347_RS16270	COG0142	geranyltranstransferase activity
CS347_RS16275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CS347_RS16280	COG1469	GTP cyclohydrolase I activity
CS347_RS16285	COG0360	Binds together with S18 to 16S ribosomal RNA
CS347_RS16290	COG2965	DNA replication, synthesis of RNA primer
CS347_RS16295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CS347_RS16300	COG0359	binds to the 23S rRNA
CS347_RS16310	COG0305	Participates in initiation and elongation during chromosome replication
CS347_RS16320	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CS347_RS16325	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CS347_RS16330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CS347_RS16335	COG3737	Protein of unknown function (DUF498/DUF598)
CS347_RS16340	COG0436	Aminotransferase
CS347_RS16360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CS347_RS16365	COG0308	aminopeptidase N
CS347_RS16380	COG0312	modulator of DNA gyrase
CS347_RS16385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS347_RS16390	COG0277	FAD linked oxidase domain protein
CS347_RS16395	COG0277	FAD linked oxidase domain protein
CS347_RS16400	COG0277	FAD linked oxidase domain protein
CS347_RS16405	COG0247	lactate metabolic process
CS347_RS16430	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS16435	COG0583	DNA-binding transcription factor activity
CS347_RS16440	COG0482	sulfurtransferase activity
CS347_RS16445	COG0730	response to heat
CS347_RS16450	COG0625	glutathione transferase activity
CS347_RS16460	COG3909	cytochrome
CS347_RS16490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CS347_RS16500	COG3706	GGDEF domain
CS347_RS16525	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CS347_RS16530	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CS347_RS16540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS347_RS16545	COG0069	glutamate synthase activity
CS347_RS16550	COG2391	methyltransferase activity
CS347_RS16555	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CS347_RS16560	COG0679	Auxin Efflux Carrier
CS347_RS16590	COG0557	exoribonuclease II activity
CS347_RS16595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS347_RS16605	COG0776	regulation of translation
CS347_RS16635	COG0642	Histidine kinase
CS347_RS16640	COG3158	transport of potassium into the cell
CS347_RS16650	COG0137	argininosuccinate synthase activity
CS347_RS16655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CS347_RS16660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CS347_RS16670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS347_RS16685	COG2186	Transcriptional regulator
CS347_RS16705	COG3836	Belongs to the HpcH HpaI aldolase family
CS347_RS16710	COG0268	Binds directly to 16S ribosomal RNA
CS347_RS16735	COG0728	peptidoglycan biosynthetic process
CS347_RS16745	COG0563	adenylate kinase activity
CS347_RS16750	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CS347_RS16755	COG2835	tetraacyldisaccharide 4'-kinase activity
CS347_RS16760	COG1663	tetraacyldisaccharide 4'-kinase activity
CS347_RS16770	COG0811	peptide transport
CS347_RS16775	COG1570	exodeoxyribonuclease VII activity
CS347_RS16780	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS347_RS16785	COG0038	chloride channel
CS347_RS16790	COG0183	Belongs to the thiolase family
CS347_RS16800	COG1278	Cold shock
CS347_RS16805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CS347_RS16815	COG4953	penicillin-binding protein 1C
CS347_RS16820	COG0542	response to heat
CS347_RS16825	COG2995	paraquat-inducible protein a
CS347_RS16830	COG3008	intermembrane lipid transfer
CS347_RS16840	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS347_RS16840	COG0506	proline dehydrogenase activity
CS347_RS16840	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CS347_RS16870	COG2271	Major facilitator Superfamily
CS347_RS16880	COG0004	ammonium transporteR
CS347_RS16885	COG0347	Belongs to the P(II) protein family
CS347_RS16905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CS347_RS16910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CS347_RS16915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CS347_RS16920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS347_RS16920	COG0072	phenylalanine-tRNA ligase activity
CS347_RS16925	COG0776	regulation of translation
CS347_RS16965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CS347_RS16990	COG1522	sequence-specific DNA binding
CS347_RS17040	COG5265	(ABC) transporter
CS347_RS17045	COG0656	L-ascorbic acid biosynthetic process
CS347_RS17050	COG0667	Aldo Keto reductase
CS347_RS17065	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CS347_RS17090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CS347_RS17110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS347_RS17115	COG3246	L-lysine catabolic process to acetate
CS347_RS17120	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS17125	COG0583	DNA-binding transcription factor activity
CS347_RS17135	COG0129	dihydroxy-acid dehydratase activity
CS347_RS17140	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS17185	COG0154	amidase activity
CS347_RS17190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS17220	COG2267	carboxylic ester hydrolase activity
CS347_RS17225	COG0501	Belongs to the peptidase M48B family
CS347_RS17235	COG0789	Transcriptional regulator
CS347_RS17240	COG0778	Nitroreductase
CS347_RS17245	COG0165	Argininosuccinate lyase
CS347_RS17250	COG0668	transmembrane transport
CS347_RS17255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CS347_RS17255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS347_RS17270	COG0583	DNA-binding transcription factor activity
CS347_RS17280	COG0747	negative chemotaxis
CS347_RS17285	COG0601	transmembrane transport
CS347_RS17290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS17295	COG4172	Belongs to the ABC transporter superfamily
CS347_RS17305	COG1280	lysine exporter protein (LysE YggA)
CS347_RS17315	COG3161	chorismate lyase activity
CS347_RS17320	COG1187	pseudouridine synthase activity
CS347_RS17330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS17355	COG1999	signal sequence binding
CS347_RS17365	COG0339	signal peptide processing
CS347_RS17370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CS347_RS17375	COG4566	intracellular signal transduction
CS347_RS17385	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CS347_RS17390	COG0508	dehydrogenase complex catalyzes the overall conversion of
CS347_RS17395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CS347_RS17440	COG0745	RESPONSE REGULATOR receiver
CS347_RS17455	COG0840	transmembrane signaling receptor activity
CS347_RS17460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CS347_RS17465	COG2201	protein-glutamate methylesterase activity
CS347_RS17470	COG0745	RESPONSE REGULATOR receiver
CS347_RS17475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CS347_RS17480	COG0840	transmembrane signaling receptor activity
CS347_RS17505	COG2747	anti-sigma28 factor FlgM
CS347_RS17530	COG1749	Flagellar hook protein flgE
CS347_RS17550	COG1706	bacterial-type flagellum-dependent cell motility
CS347_RS17560	COG1256	bacterial-type flagellum assembly
CS347_RS17570	COG0840	transmembrane signaling receptor activity
CS347_RS17580	COG0840	transmembrane signaling receptor activity
CS347_RS17585	COG0840	transmembrane signaling receptor activity
CS347_RS17610	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS347_RS17620	COG1580	Controls the rotational direction of flagella during chemotaxis
CS347_RS17630	COG2882	bacterial-type flagellum organization
CS347_RS17640	COG1317	bacterial-type flagellum organization
CS347_RS17645	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CS347_RS17650	COG1766	The M ring may be actively involved in energy transduction
CS347_RS17655	COG1677	Flagellar hook-basal body complex protein FliE
CS347_RS17665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CS347_RS17685	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CS347_RS17705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS17710	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS17720	COG0285	dihydrofolate synthase activity
CS347_RS17730	COG1286	toxin biosynthetic process
CS347_RS17750	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CS347_RS17755	COG0024	Methionine aminopeptidase
CS347_RS17760	COG0052	Belongs to the universal ribosomal protein uS2 family
CS347_RS17765	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CS347_RS17770	COG0528	UMP kinase activity
CS347_RS17775	COG0233	cytoplasmic translational termination
CS347_RS17780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CS347_RS17785	COG0575	Belongs to the CDS family
CS347_RS17790	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CS347_RS17795	COG0750	zinc metalloprotease
CS347_RS17800	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CS347_RS17810	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS347_RS17815	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CS347_RS17825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CS347_RS17830	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CS347_RS17835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CS347_RS17845	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CS347_RS17870	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CS347_RS17880	COG2914	Belongs to the UPF0125 (RnfH) family
CS347_RS17885	COG1960	acyl-CoA dehydrogenase activity
CS347_RS17890	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS17890	COG1024	Enoyl-CoA hydratase
CS347_RS17910	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CS347_RS17915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CS347_RS17925	COG0084	hydrolase, TatD family'
CS347_RS17940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS17945	COG0765	amino acid transport
CS347_RS17950	COG1126	abc transporter atp-binding protein
CS347_RS17955	COG0010	Belongs to the arginase family
CS347_RS17975	COG4221	oxidoreductase activity
CS347_RS17980	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CS347_RS17990	COG2059	Chromate
CS347_RS17995	COG0640	Transcriptional regulator
CS347_RS18005	COG0740	serine-type endopeptidase activity
CS347_RS18015	COG0095	Lipoate-protein ligase
CS347_RS18040	COG0386	Belongs to the glutathione peroxidase family
CS347_RS18065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS18110	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS18115	COG2259	Doxx family
CS347_RS18135	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS18145	COG0842	Transport permease protein
CS347_RS18150	COG1129	ABC transporter
CS347_RS18150	COG0842	Transport permease protein
CS347_RS18155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CS347_RS18165	COG3243	poly(R)-hydroxyalkanoic acid synthase
CS347_RS18185	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CS347_RS18210	COG2733	membrane
CS347_RS18220	COG3042	response to heat
CS347_RS18225	COG3258	Cytochrome c
CS347_RS18255	COG3958	Transketolase
CS347_RS18260	COG3959	Transketolase, thiamine diphosphate binding domain
CS347_RS18270	COG1802	Transcriptional regulator
CS347_RS18320	COG0583	DNA-binding transcription factor activity
CS347_RS18325	COG0028	Belongs to the TPP enzyme family
CS347_RS18330	COG0477	Major facilitator Superfamily
CS347_RS18335	COG0583	DNA-binding transcription factor activity
CS347_RS18340	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS18345	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS18355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CS347_RS18375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS347_RS18375	COG0519	Catalyzes the synthesis of GMP from XMP
CS347_RS18390	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS18405	COG1024	Enoyl-CoA hydratase
CS347_RS18420	COG1960	acyl-CoA dehydrogenase activity
CS347_RS18425	COG1960	acyl-CoA dehydrogenase activity
CS347_RS18470	COG1122	ATPase activity
CS347_RS18485	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CS347_RS18490	COG2900	Belongs to the SlyX family
CS347_RS18505	COG0456	acetyltransferase
CS347_RS18510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS347_RS18545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CS347_RS18580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS18630	COG0066	3-isopropylmalate dehydratase activity
CS347_RS18635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CS347_RS18640	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS18645	COG4948	Mandelate Racemase Muconate Lactonizing
CS347_RS18650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CS347_RS18655	COG3842	ATPase activity
CS347_RS18660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CS347_RS18670	COG3833	ABC-type maltose transport systems, permease component
CS347_RS18675	COG1175	transmembrane transport
CS347_RS18680	COG2182	Extracellular solute-binding protein
CS347_RS18690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS18695	COG0765	amino acid transport
CS347_RS18700	COG0765	amino acid transport
CS347_RS18715	COG3665	Urea carboxylase-associated protein
CS347_RS18735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS347_RS18760	COG1937	Protein conserved in bacteria
CS347_RS18780	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS18805	COG2863	cytochrome
CS347_RS18810	COG3568	Endonuclease Exonuclease Phosphatase
CS347_RS18815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CS347_RS18820	COG0392	lysyltransferase activity
CS347_RS18825	COG0166	Belongs to the GPI family
CS347_RS18840	COG1546	Belongs to the CinA family
CS347_RS18840	COG1058	Belongs to the CinA family
CS347_RS18850	COG0668	transmembrane transport
CS347_RS18855	COG0297	glycogen (starch) synthase activity
CS347_RS18865	COG0366	Alpha amylase catalytic
CS347_RS18870	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS347_RS18880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CS347_RS18885	COG1640	4-alpha-glucanotransferase
CS347_RS18915	COG3685	Protein conserved in bacteria
CS347_RS18920	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CS347_RS18925	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS18935	COG1216	Glycosyl transferase, family 2
CS347_RS18970	COG2192	nodulation
CS347_RS18980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CS347_RS18990	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS18995	COG0438	transferase activity, transferring glycosyl groups
CS347_RS19010	COG5265	(ABC) transporter
CS347_RS19030	COG0028	Belongs to the TPP enzyme family
CS347_RS19035	COG2204	response regulator
CS347_RS19040	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CS347_RS19045	COG0583	DNA-binding transcription factor activity
CS347_RS19050	COG0477	Major facilitator Superfamily
CS347_RS19055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS347_RS19075	COG1137	ATPase activity
CS347_RS19085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CS347_RS19100	COG1172	Belongs to the binding-protein-dependent transport system permease family
CS347_RS19105	COG1129	ABC transporter
CS347_RS19145	COG0402	S-adenosylhomocysteine deaminase activity
CS347_RS19150	COG0747	negative chemotaxis
CS347_RS19155	COG0601	transmembrane transport
CS347_RS19160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CS347_RS19165	COG4172	Belongs to the ABC transporter superfamily
CS347_RS19170	COG1063	alcohol dehydrogenase
CS347_RS19195	COG2175	clavaminate synthase activity
CS347_RS19200	COG1454	alcohol dehydrogenase
CS347_RS19205	COG0583	DNA-binding transcription factor activity
CS347_RS19215	COG1024	Enoyl-CoA hydratase
CS347_RS19225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS19235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CS347_RS19245	COG1250	3-hydroxyacyl-CoA dehydrogenase
CS347_RS19245	COG1024	Enoyl-CoA hydratase
CS347_RS19250	COG0183	Belongs to the thiolase family
CS347_RS19255	COG1960	acyl-CoA dehydrogenase activity
CS347_RS19260	COG0318	PFAM AMP-dependent synthetase and ligase
CS347_RS19265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CS347_RS19280	COG0154	amidase activity
CS347_RS19285	COG2271	Major facilitator Superfamily
CS347_RS19295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CS347_RS19325	COG0318	PFAM AMP-dependent synthetase and ligase
CS347_RS19335	COG2267	carboxylic ester hydrolase activity
CS347_RS19345	COG1024	Enoyl-CoA hydratase
CS347_RS19355	COG0431	NADPH-dependent FMN reductase
CS347_RS19370	COG0683	leucine binding
CS347_RS19395	COG2819	hydrolase of the alpha beta superfamily
CS347_RS19410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CS347_RS19420	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS347_RS19450	COG1126	abc transporter atp-binding protein
CS347_RS19455	COG0765	amino acid transport
CS347_RS19460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS19485	COG0410	ABC transporter
CS347_RS19505	COG2200	EAL domain
CS347_RS19515	COG1595	DNA-templated transcription, initiation
CS347_RS19530	COG1253	flavin adenine dinucleotide binding
CS347_RS19540	COG4251	negative regulation of phosphorylation
CS347_RS19540	COG3706	GGDEF domain
CS347_RS19540	COG2203	Gaf domain
CS347_RS19540	COG5001	Diguanylate cyclase
CS347_RS19545	COG2197	response regulator
CS347_RS19550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS19550	COG2205	protein histidine kinase activity
CS347_RS19555	COG2814	Major facilitator Superfamily
CS347_RS19560	COG0076	glutamate decarboxylase activity
CS347_RS19565	COG2985	domain, Protein
CS347_RS19570	COG3189	MarR family transcriptional regulator
CS347_RS19575	COG2186	Transcriptional regulator
CS347_RS19580	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS19590	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS347_RS19590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS347_RS19600	COG0028	Belongs to the TPP enzyme family
CS347_RS19610	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS19620	COG0688	phosphatidylethanolamine metabolic process
CS347_RS19630	COG1464	Belongs to the NlpA lipoprotein family
CS347_RS19650	COG2363	Small membrane protein
CS347_RS19655	COG0697	spore germination
CS347_RS19665	COG2133	pyrroloquinoline quinone binding
CS347_RS19670	COG0625	glutathione transferase activity
CS347_RS19680	COG1794	racemase activity, acting on amino acids and derivatives
CS347_RS19700	COG0559	Belongs to the binding-protein-dependent transport system permease family
CS347_RS19710	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CS347_RS19725	COG1175	transmembrane transport
CS347_RS19730	COG0395	ABC-type sugar transport system, permease component
CS347_RS19735	COG3842	ATPase activity
CS347_RS19750	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CS347_RS19765	COG0438	transferase activity, transferring glycosyl groups
CS347_RS19785	COG1216	Glycosyl transferase, family 2
CS347_RS19800	COG0783	Belongs to the Dps family
CS347_RS19810	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CS347_RS19825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CS347_RS19870	COG0583	DNA-binding transcription factor activity
CS347_RS19875	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CS347_RS19895	COG1840	ABC-type Fe3 transport system, periplasmic component
CS347_RS19905	COG3842	ATPase activity
CS347_RS19910	COG1741	Belongs to the pirin family
CS347_RS19915	COG1741	Belongs to the pirin family
CS347_RS19920	COG0583	DNA-binding transcription factor activity
CS347_RS19935	COG5002	protein histidine kinase activity
CS347_RS19935	COG0784	Response regulator, receiver
CS347_RS19935	COG2205	protein histidine kinase activity
CS347_RS19950	COG3852	Histidine kinase
CS347_RS19955	COG0174	glutamine synthetase
CS347_RS19960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS347_RS19965	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CS347_RS19970	COG3300	MHYT domain
CS347_RS19970	COG5001	Diguanylate cyclase
CS347_RS19975	COG0840	transmembrane signaling receptor activity
CS347_RS19985	COG1960	acyl-CoA dehydrogenase activity
CS347_RS19990	COG2079	MmgE PrpD family protein
CS347_RS20000	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CS347_RS20005	COG1561	YicC-like family, N-terminal region
CS347_RS20020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CS347_RS20025	COG0791	NLP P60 protein
CS347_RS20030	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS20035	COG0194	GDP metabolic process
CS347_RS20040	COG1758	RNA polymerase activity
CS347_RS20045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CS347_RS20050	COG1126	abc transporter atp-binding protein
CS347_RS20055	COG0765	amino acid transport
CS347_RS20060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS20085	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS20100	COG2831	hemolysin activation secretion protein
CS347_RS20110	COG3188	usher protein
CS347_RS20115	COG3121	Chaperone
CS347_RS20125	COG3064	Membrane
CS347_RS20125	COG3210	domain, Protein
CS347_RS20125	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS347_RS20125	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CS347_RS20125	COG3210	domain, Protein
CS347_RS20125	COG3064	Membrane
CS347_RS20135	COG4181	ATPase activity
CS347_RS20145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS347_RS20150	COG0584	glycerophosphoryl diester phosphodiesterase
CS347_RS20155	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CS347_RS20165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CS347_RS20165	COG0678	peroxiredoxin activity
CS347_RS20180	COG0789	Transcriptional regulator
CS347_RS20185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CS347_RS20210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CS347_RS20220	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CS347_RS20240	COG3618	amidohydrolase
CS347_RS20245	COG0583	DNA-binding transcription factor activity
CS347_RS20250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CS347_RS20255	COG2252	PERMEase
CS347_RS20260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CS347_RS20265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CS347_RS20295	COG0583	DNA-binding transcription factor activity
CS347_RS20300	COG0655	NAD(P)H dehydrogenase (quinone) activity
CS347_RS20305	COG0488	(ABC) transporter
CS347_RS20310	COG1619	proteins homologs of microcin C7 resistance protein MccF
CS347_RS20315	COG0590	tRNA wobble adenosine to inosine editing
CS347_RS20330	COG1320	monovalent cation:proton antiporter activity
CS347_RS20335	COG2212	antiporter activity
CS347_RS20345	COG0651	ATP synthesis coupled electron transport
CS347_RS20350	COG1006	Multisubunit Na H antiporter MnhC subunit
CS347_RS20355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CS347_RS20355	COG2111	Na H antiporter
CS347_RS20360	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS20370	COG0420	3'-5' exonuclease activity
CS347_RS20375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CS347_RS20380	COG1522	sequence-specific DNA binding
CS347_RS20395	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CS347_RS20435	COG1131	(ABC) transporter
CS347_RS20440	COG0842	Transport permease protein
CS347_RS20450	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CS347_RS20485	COG0235	Class ii aldolase
CS347_RS20490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CS347_RS20495	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS20505	COG1414	Transcriptional regulator
CS347_RS20510	COG0602	queuosine metabolic process
CS347_RS20515	COG0720	synthase
CS347_RS20525	COG1289	transmembrane transporter activity
CS347_RS20535	COG1566	PFAM secretion protein HlyD family protein
CS347_RS20545	COG0400	carboxylic ester hydrolase activity
CS347_RS20550	COG0840	transmembrane signaling receptor activity
CS347_RS20565	COG0587	DNA-directed DNA polymerase activity
CS347_RS20575	COG0390	transport system, permease component
CS347_RS20580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CS347_RS20585	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CS347_RS20625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CS347_RS20635	COG1280	lysine exporter protein (LysE YggA)
CS347_RS20640	COG1280	lysine exporter protein (LysE YggA)
CS347_RS20645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CS347_RS20665	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CS347_RS20690	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS20715	COG0583	DNA-binding transcription factor activity
CS347_RS20730	COG1522	sequence-specific DNA binding
CS347_RS20740	COG2814	Major facilitator Superfamily
CS347_RS20755	COG1396	sequence-specific DNA binding
CS347_RS20775	COG0183	Belongs to the thiolase family
CS347_RS20780	COG0583	DNA-binding transcription factor activity
CS347_RS20785	COG2814	Major facilitator Superfamily
CS347_RS20790	COG0656	L-ascorbic acid biosynthetic process
CS347_RS20795	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CS347_RS20800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS20810	COG2807	transmembrane transport
CS347_RS20815	COG2207	Transcriptional regulator
CS347_RS20830	COG1960	acyl-CoA dehydrogenase activity
CS347_RS20835	COG1024	Enoyl-CoA hydratase
CS347_RS20850	COG1309	transcriptional regulator
CS347_RS20865	COG0653	protein targeting
CS347_RS20900	COG4585	Histidine kinase
CS347_RS20910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CS347_RS20915	COG1595	DNA-templated transcription, initiation
CS347_RS20920	COG3712	iron ion homeostasis
CS347_RS20925	COG4774	siderophore transport
CS347_RS20930	COG2814	Major facilitator Superfamily
CS347_RS20935	COG0583	DNA-binding transcription factor activity
CS347_RS20940	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS20950	COG1349	DNA-binding transcription factor activity
CS347_RS20960	COG1012	belongs to the aldehyde dehydrogenase family
CS347_RS20970	COG0411	ABC transporter
CS347_RS21010	COG0384	phenazine biosynthesis protein PhzF
CS347_RS21015	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS21030	COG5489	Protein of unknown function (DUF736)
CS347_RS21050	COG0519	Catalyzes the synthesis of GMP from XMP
CS347_RS21050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CS347_RS21065	COG1695	Transcriptional regulator
CS347_RS21080	COG2072	flavoprotein involved in K transport
CS347_RS21085	COG0601	transmembrane transport
CS347_RS21095	COG0444	Belongs to the ABC transporter superfamily
CS347_RS21100	COG4608	Belongs to the ABC transporter superfamily
CS347_RS21105	COG0747	negative chemotaxis
CS347_RS21145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CS347_RS21145	COG0047	phosphoribosylformylglycinamidine synthase activity
CS347_RS21155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS347_RS21160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CS347_RS21160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CS347_RS21165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CS347_RS21175	COG0613	PHP domain protein
CS347_RS21200	COG2501	S4 domain
CS347_RS21205	COG0084	hydrolase, TatD family'
CS347_RS21210	COG1136	(ABC) transporter
CS347_RS21225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CS347_RS21235	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS21240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CS347_RS21250	COG1309	transcriptional regulator
CS347_RS21255	COG1022	Amp-dependent synthetase and ligase
CS347_RS21285	COG1024	Enoyl-CoA hydratase
CS347_RS21290	COG1803	Methylglyoxal synthase
CS347_RS21300	COG2975	iron-sulfur cluster assembly
CS347_RS21305	COG0633	Ferredoxin
CS347_RS21310	COG0443	Heat shock 70 kDa protein
CS347_RS21315	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CS347_RS21320	COG0316	Belongs to the HesB IscA family
CS347_RS21325	COG0822	iron-sulfur transferase activity
CS347_RS21330	COG1104	cysteine desulfurase activity
CS347_RS21340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CS347_RS21345	COG0556	nucleotide-excision repair
CS347_RS21355	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CS347_RS21360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS347_RS21365	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CS347_RS21370	COG0740	serine-type endopeptidase activity
CS347_RS21375	COG0544	peptidyl-prolyl cis-trans isomerase activity
CS347_RS21385	COG1278	Cold shock
CS347_RS21395	COG1278	Cold shock
CS347_RS21425	COG3468	outer membrane autotransporter barrel domain protein
CS347_RS21600	COG0305	Participates in initiation and elongation during chromosome replication
CS347_RS21685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CS347_RS21695	COG3723	Recombinational DNA repair protein, rece pathway
CS347_RS21770	COG2171	N-acyltransferase activity
CS347_RS21775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CS347_RS21780	COG2890	protein-(glutamine-N5) methyltransferase activity
CS347_RS21785	COG0488	(ABC) transporter
CS347_RS21790	COG0210	DNA helicase
CS347_RS21805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CS347_RS21805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CS347_RS21810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CS347_RS21815	COG0196	riboflavin kinase activity
CS347_RS21820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CS347_RS21825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CS347_RS21830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CS347_RS21840	COG1522	sequence-specific DNA binding
CS347_RS21855	COG0586	Pfam SNARE associated Golgi protein
CS347_RS21865	COG0756	dUTP diphosphatase activity
CS347_RS21870	COG1902	pentaerythritol trinitrate reductase activity
CS347_RS21875	COG1126	abc transporter atp-binding protein
CS347_RS21880	COG0765	amino acid transport
CS347_RS21885	COG0765	amino acid transport
CS347_RS21890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CS347_RS21900	COG2423	ornithine cyclodeaminase activity
CS347_RS21905	COG1764	response to oxidative stress
CS347_RS21910	COG1914	H( )-stimulated, divalent metal cation uptake system
CS347_RS21915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CS347_RS21920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CS347_RS21935	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CS347_RS21940	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CS347_RS21945	COG2197	response regulator
CS347_RS21950	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CS347_RS21970	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS21975	COG0840	transmembrane signaling receptor activity
CS347_RS21995	COG0135	phosphoribosylanthranilate isomerase activity
CS347_RS22000	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CS347_RS22005	COG0101	tRNA pseudouridine synthase activity
CS347_RS22015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CS347_RS22020	COG0473	3-isopropylmalate dehydrogenase activity
CS347_RS22025	COG0066	3-isopropylmalate dehydratase activity
CS347_RS22035	COG2197	response regulator
CS347_RS22050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CS347_RS22060	COG2205	protein histidine kinase activity
CS347_RS22070	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CS347_RS22080	COG1295	ribonuclease BN
CS347_RS22090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CS347_RS22120	COG1450	Type ii and iii secretion system protein
CS347_RS22155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CS347_RS22195	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS22210	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS22240	COG0181	hydroxymethylbilane synthase activity
CS347_RS22245	COG0861	Integral membrane protein TerC family
CS347_RS22250	COG0861	Integral membrane protein TerC family
CS347_RS22255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CS347_RS22260	COG0045	succinate-CoA ligase (ADP-forming) activity
CS347_RS22270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CS347_RS22280	COG2137	regulation of response to DNA damage stimulus
CS347_RS22285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CS347_RS22310	COG2974	May be involved in recombination
CS347_RS22315	COG0540	Belongs to the ATCase OTCase family
CS347_RS22345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CS347_RS22375	COG0500	methyltransferase
CS347_RS22380	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS22395	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CS347_RS22400	COG0747	negative chemotaxis
CS347_RS22420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CS347_RS22445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CS347_RS22475	COG0811	peptide transport
CS347_RS22510	COG2188	Transcriptional regulator
CS347_RS22515	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS22530	COG0583	DNA-binding transcription factor activity
CS347_RS22540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CS347_RS22550	COG4172	Belongs to the ABC transporter superfamily
CS347_RS22560	COG0601	transmembrane transport
CS347_RS22565	COG4166	transmembrane transport
CS347_RS22570	COG2267	carboxylic ester hydrolase activity
CS347_RS22575	COG4638	Rieske (2fe-2S)
CS347_RS22585	COG0583	DNA-binding transcription factor activity
CS347_RS22590	COG2146	nitrite reductase [NAD(P)H] activity
CS347_RS22595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CS347_RS22600	COG1595	DNA-templated transcription, initiation
CS347_RS22605	COG3712	iron ion homeostasis
CS347_RS22610	COG4774	siderophore transport
CS347_RS22635	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CS347_RS22645	COG3246	L-lysine catabolic process to acetate
CS347_RS22650	COG3181	Tripartite tricarboxylate transporter family receptor
CS347_RS22665	COG1028	Short-chain dehydrogenase reductase Sdr
CS347_RS22670	COG0583	DNA-binding transcription factor activity
CS347_RS22700	COG0457	Tetratricopeptide repeat
CS347_RS22705	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CS347_RS22710	COG1215	transferase activity, transferring glycosyl groups
CS347_RS22715	COG1215	transferase activity, transferring glycosyl groups
CS347_RS22720	COG1215	transferase activity, transferring glycosyl groups
CS347_RS22725	COG0003	Pfam Anion-transporting ATPase
CS347_RS22745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CS347_RS22785	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CS347_RS22800	COG1215	transferase activity, transferring glycosyl groups
CS347_RS22810	COG3307	-O-antigen