locus-tag	class	description
CBR68_RS00025	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS00035	COG2030	dehydratase
CBR68_RS00050	COG1024	Enoyl-CoA hydratase
CBR68_RS00100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS00130	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS00135	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS00150	COG0583	DNA-binding transcription factor activity
CBR68_RS00155	COG0372	Belongs to the citrate synthase family
CBR68_RS00200	COG0701	Predicted permease
CBR68_RS00240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR68_RS00275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBR68_RS00285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR68_RS00290	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CBR68_RS00300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBR68_RS00305	COG3620	sequence-specific DNA binding
CBR68_RS00310	COG2233	PERMEase
CBR68_RS00340	COG0406	alpha-ribazole phosphatase activity
CBR68_RS00345	COG4221	oxidoreductase activity
CBR68_RS00355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBR68_RS00360	COG0505	Belongs to the CarA family
CBR68_RS00365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBR68_RS00370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR68_RS00380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR68_RS00385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS00390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBR68_RS00395	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBR68_RS00400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBR68_RS00410	COG1074	ATP-dependent DNA helicase activity
CBR68_RS00430	COG1686	Belongs to the peptidase S11 family
CBR68_RS00440	COG0693	protein deglycase activity
CBR68_RS00450	COG4974	Belongs to the 'phage' integrase family
CBR68_RS00455	COG0583	DNA-binding transcription factor activity
CBR68_RS00460	COG0028	Belongs to the TPP enzyme family
CBR68_RS00465	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS00475	COG0028	Belongs to the TPP enzyme family
CBR68_RS00480	COG1126	abc transporter atp-binding protein
CBR68_RS00485	COG0765	amino acid transport
CBR68_RS00490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS00505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS00510	COG0009	L-threonylcarbamoyladenylate synthase
CBR68_RS00515	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBR68_RS00520	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CBR68_RS00530	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBR68_RS00540	COG1301	dicarboxylic acid transport
CBR68_RS00545	COG0456	acetyltransferase
CBR68_RS00575	COG3454	Phosphonate metabolism
CBR68_RS00580	COG4778	phosphonate C-P lyase system protein PhnL
CBR68_RS00585	COG4107	phosphonate C-P lyase system protein PhnK
CBR68_RS00590	COG3627	carbon phosphorus lyase activity
CBR68_RS00595	COG3626	phosphonate metabolism
CBR68_RS00605	COG3624	Phosphonate C-P lyase system protein PhnG
CBR68_RS00610	COG2188	Transcriptional regulator
CBR68_RS00615	COG3454	Phosphonate metabolism
CBR68_RS00625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CBR68_RS00630	COG3639	organic phosphonate transmembrane transporter activity
CBR68_RS00635	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CBR68_RS00640	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR68_RS00645	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR68_RS00655	COG0739	heme binding
CBR68_RS00665	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR68_RS00670	COG0306	phosphate transporter
CBR68_RS00715	COG0625	glutathione transferase activity
CBR68_RS00735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBR68_RS00740	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBR68_RS00750	COG0126	phosphoglycerate kinase activity
CBR68_RS00755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBR68_RS00760	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBR68_RS00765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CBR68_RS00780	COG0280	phosphate acetyltransferase
CBR68_RS00780	COG0281	malic enzyme
CBR68_RS00790	COG0436	Aminotransferase
CBR68_RS00795	COG0741	lytic transglycosylase activity
CBR68_RS00800	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CBR68_RS00815	COG4575	ribosome binding
CBR68_RS00825	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CBR68_RS00825	COG1648	precorrin-2 dehydrogenase activity
CBR68_RS00830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBR68_RS00835	COG2027	D-alanyl-D-alanine carboxypeptidase
CBR68_RS00840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBR68_RS00845	COG0343	queuine tRNA-ribosyltransferase activity
CBR68_RS00850	COG1862	Preprotein translocase
CBR68_RS00855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR68_RS00860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR68_RS00890	COG0667	Aldo Keto reductase
CBR68_RS00895	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBR68_RS00900	COG4535	Mg2 and Co2 transporter CorC
CBR68_RS00905	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBR68_RS00910	COG1702	phosphate starvation-inducible protein PhoH
CBR68_RS00915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR68_RS00965	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBR68_RS00970	COG0697	spore germination
CBR68_RS00980	COG0494	nUDIX hydrolase
CBR68_RS00990	COG0583	DNA-binding transcription factor activity
CBR68_RS00995	COG3530	Putative quorum-sensing-regulated virulence factor
CBR68_RS01005	COG2814	Major facilitator Superfamily
CBR68_RS01025	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS01030	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS01035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS01045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR68_RS01050	COG0583	DNA-binding transcription factor activity
CBR68_RS01090	COG2814	Major facilitator Superfamily
CBR68_RS01100	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CBR68_RS01110	COG0628	permease
CBR68_RS01115	COG0842	Transport permease protein
CBR68_RS01120	COG1131	(ABC) transporter
CBR68_RS01125	COG1764	response to oxidative stress
CBR68_RS01130	COG1846	Transcriptional regulator
CBR68_RS01145	COG0348	domain, Protein
CBR68_RS01165	COG3278	Belongs to the heme-copper respiratory oxidase family
CBR68_RS01175	COG2217	Heavy metal translocating P-type atpase
CBR68_RS01180	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS01185	COG0156	8-amino-7-oxononanoate synthase activity
CBR68_RS01195	COG4106	trans-aconitate 2-methyltransferase activity
CBR68_RS01195	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBR68_RS01200	COG2224	Isocitrate lyase
CBR68_RS01205	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR68_RS01205	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR68_RS01215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CBR68_RS01225	COG1472	Belongs to the glycosyl hydrolase 3 family
CBR68_RS01230	COG0736	holo-[acyl-carrier-protein] synthase activity
CBR68_RS01235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CBR68_RS01245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR68_RS01250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS01255	COG0745	RESPONSE REGULATOR receiver
CBR68_RS01275	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR68_RS01280	COG4149	molybdate abc transporter
CBR68_RS01285	COG0725	ABC transporter, periplasmic molybdate-binding protein
CBR68_RS01295	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS01305	COG0667	Aldo Keto reductase
CBR68_RS01310	COG2032	superoxide dismutase activity
CBR68_RS01320	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS01325	COG1024	Enoyl-CoA hydratase
CBR68_RS01335	COG1802	Transcriptional regulator
CBR68_RS01355	COG1217	gtp-binding protein TYPA
CBR68_RS01360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBR68_RS01365	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBR68_RS01370	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBR68_RS01375	COG2251	uridine kinase activity
CBR68_RS01375	COG0195	Participates in both transcription termination and antitermination
CBR68_RS01380	COG0779	Required for maturation of 30S ribosomal subunits
CBR68_RS01385	COG1187	pseudouridine synthase activity
CBR68_RS01390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBR68_RS01400	COG0583	DNA-binding transcription factor activity
CBR68_RS01405	COG0523	cobalamin synthesis protein
CBR68_RS01435	COG0625	glutathione transferase activity
CBR68_RS01440	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBR68_RS01450	COG2003	Belongs to the UPF0758 family
CBR68_RS01455	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CBR68_RS01460	COG3483	tryptophan 2,3-dioxygenase activity
CBR68_RS01465	COG0254	rRNA binding
CBR68_RS01500	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS01505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBR68_RS01515	COG1562	ergosterol biosynthetic process
CBR68_RS01520	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR68_RS01520	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR68_RS01525	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBR68_RS01550	COG1477	protein flavinylation
CBR68_RS01555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CBR68_RS01565	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR68_RS01575	COG0542	response to heat
CBR68_RS01585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBR68_RS01600	COG0678	peroxiredoxin activity
CBR68_RS01610	COG0412	Dienelactone hydrolase
CBR68_RS01620	COG0315	cyclic pyranopterin monophosphate synthase activity
CBR68_RS01630	COG0314	molybdopterin synthase activity
CBR68_RS01635	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR68_RS01640	COG0303	'Molybdopterin
CBR68_RS01645	COG0746	molybdenum cofactor guanylyltransferase activity
CBR68_RS01650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBR68_RS01670	COG3383	formate dehydrogenase (NAD+) activity
CBR68_RS01685	COG2264	protein methyltransferase activity
CBR68_RS01705	COG5006	permease, DMT superfamily
CBR68_RS01710	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS01760	COG1129	ABC transporter
CBR68_RS01770	COG1666	GTP binding
CBR68_RS01800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR68_RS01805	COG1845	cytochrome c oxidase, subunit III
CBR68_RS01810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR68_RS01820	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CBR68_RS01845	COG0783	Belongs to the Dps family
CBR68_RS01860	COG1346	cytolysis
CBR68_RS01865	COG1380	Effector of murein hydrolase LrgA
CBR68_RS01870	COG0583	DNA-binding transcription factor activity
CBR68_RS01880	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS01885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS01890	COG0601	transmembrane transport
CBR68_RS01895	COG0747	negative chemotaxis
CBR68_RS01905	COG0598	Magnesium transport protein CorA
CBR68_RS01910	COG0210	DNA helicase
CBR68_RS01925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR68_RS01930	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS01940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR68_RS01950	COG1045	serine acetyltransferase
CBR68_RS01955	COG1309	transcriptional regulator
CBR68_RS01960	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS01970	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS01970	COG1024	Enoyl-CoA hydratase
CBR68_RS01975	COG2067	long-chain fatty acid transport protein
CBR68_RS01980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS01980	COG1024	Enoyl-CoA hydratase
CBR68_RS01985	COG0183	Belongs to the thiolase family
CBR68_RS02000	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS02010	COG2814	Major facilitator Superfamily
CBR68_RS02020	COG1309	transcriptional regulator
CBR68_RS02035	COG1902	pentaerythritol trinitrate reductase activity
CBR68_RS02060	COG0251	oxidation-reduction process
CBR68_RS02070	COG1832	CoA-binding protein
CBR68_RS02075	COG1414	Transcriptional regulator
CBR68_RS02090	COG0583	DNA-binding transcription factor activity
CBR68_RS02115	COG0583	DNA-binding transcription factor activity
CBR68_RS02130	COG4993	Dehydrogenase
CBR68_RS02140	COG4772	TonB-dependent receptor
CBR68_RS02145	COG2814	Major facilitator Superfamily
CBR68_RS02160	COG1132	(ABC) transporter
CBR68_RS02175	COG0037	tRNA processing
CBR68_RS02180	COG0825	malonyl-CoA metabolic process
CBR68_RS02190	COG0215	cysteine-tRNA ligase activity
CBR68_RS02200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBR68_RS02205	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR68_RS02210	COG1968	undecaprenyl-diphosphatase activity
CBR68_RS02215	COG1253	flavin adenine dinucleotide binding
CBR68_RS02220	COG0483	inositol monophosphate 1-phosphatase activity
CBR68_RS02225	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CBR68_RS02240	COG0668	transmembrane transport
CBR68_RS02265	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR68_RS02275	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR68_RS02310	COG3360	Dodecin
CBR68_RS02330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBR68_RS02335	COG2850	peptidyl-arginine hydroxylation
CBR68_RS02345	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CBR68_RS02350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR68_RS02355	COG1994	Peptidase M50
CBR68_RS02360	COG0009	L-threonylcarbamoyladenylate synthase
CBR68_RS02365	COG2321	neutral zinc metallopeptidase
CBR68_RS02390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR68_RS02395	COG0583	DNA-binding transcription factor activity
CBR68_RS02425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR68_RS02435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR68_RS02445	COG2072	flavoprotein involved in K transport
CBR68_RS02450	COG3842	ATPase activity
CBR68_RS02455	COG0604	alcohol dehydrogenase
CBR68_RS02455	COG3321	synthase
CBR68_RS02455	COG4221	oxidoreductase activity
CBR68_RS02455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR68_RS02465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR68_RS02470	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR68_RS02475	COG1177	transmembrane transport
CBR68_RS02480	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR68_RS02490	COG1126	abc transporter atp-binding protein
CBR68_RS02495	COG0765	amino acid transport
CBR68_RS02505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS02515	COG0251	oxidation-reduction process
CBR68_RS02530	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR68_RS02545	COG2020	methyltransferase activity
CBR68_RS02570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR68_RS02575	COG3608	succinylglutamate desuccinylase aspartoacylase
CBR68_RS02575	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBR68_RS02585	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS02615	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS02655	COG2202	Pas domain
CBR68_RS02655	COG2200	EAL domain
CBR68_RS02655	COG2199	diguanylate cyclase activity
CBR68_RS02660	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CBR68_RS02665	COG1414	Transcriptional regulator
CBR68_RS02685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS02715	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS02720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS02725	COG2186	Transcriptional regulator
CBR68_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS02780	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR68_RS02800	COG4604	ABC transporter, ATP-binding protein
CBR68_RS02805	COG4605	iron ion homeostasis
CBR68_RS02810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR68_RS02815	COG4607	ABC-type enterochelin transport system periplasmic component
CBR68_RS02820	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS02825	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR68_RS02830	COG0149	triose-phosphate isomerase activity
CBR68_RS02835	COG0604	alcohol dehydrogenase
CBR68_RS02835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR68_RS02835	COG3321	synthase
CBR68_RS02835	COG4221	oxidoreductase activity
CBR68_RS02860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR68_RS02865	COG0583	DNA-binding transcription factor activity
CBR68_RS02895	COG1185	polyribonucleotide nucleotidyltransferase activity
CBR68_RS02900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBR68_RS02910	COG1183	phosphatidylcholine synthase activity
CBR68_RS02915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR68_RS02920	COG0440	acetolactate synthase activity
CBR68_RS02925	COG0028	Belongs to the TPP enzyme family
CBR68_RS02930	COG1289	transmembrane transporter activity
CBR68_RS02935	COG3022	response to hydroperoxide
CBR68_RS02940	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS02965	COG1309	transcriptional regulator
CBR68_RS02980	COG2186	Transcriptional regulator
CBR68_RS02985	COG4638	Rieske (2fe-2S)
CBR68_RS02990	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CBR68_RS02995	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS03050	COG2095	MarC family integral membrane protein
CBR68_RS03060	COG5001	Diguanylate cyclase
CBR68_RS03060	COG3447	MASE1 domain protein
CBR68_RS03060	COG5002	protein histidine kinase activity
CBR68_RS03080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBR68_RS03095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBR68_RS03110	COG0601	transmembrane transport
CBR68_RS03130	COG0517	IMP dehydrogenase activity
CBR68_RS03130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBR68_RS03135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR68_RS03145	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CBR68_RS03150	COG1674	ftsk spoiiie
CBR68_RS03155	COG0492	ferredoxin-NADP+ reductase activity
CBR68_RS03160	COG1193	negative regulation of DNA recombination
CBR68_RS03170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBR68_RS03185	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CBR68_RS03190	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CBR68_RS03195	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CBR68_RS03200	COG2205	protein histidine kinase activity
CBR68_RS03205	COG0745	RESPONSE REGULATOR receiver
CBR68_RS03220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR68_RS03245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR68_RS03260	COG0612	Peptidase, M16
CBR68_RS03265	COG0484	heat shock protein binding
CBR68_RS03270	COG0443	Heat shock 70 kDa protein
CBR68_RS03280	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBR68_RS03290	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBR68_RS03295	COG1420	regulation of RNA biosynthetic process
CBR68_RS03300	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CBR68_RS03305	COG0497	DNA recombination
CBR68_RS03310	COG0735	belongs to the Fur family
CBR68_RS03315	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR68_RS03335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR68_RS03365	COG2828	Protein conserved in bacteria
CBR68_RS03370	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS03390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CBR68_RS03395	COG1802	Transcriptional regulator
CBR68_RS03400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR68_RS03405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBR68_RS03410	COG1335	isochorismatase
CBR68_RS03415	COG0523	cobalamin synthesis protein
CBR68_RS03450	COG0583	DNA-binding transcription factor activity
CBR68_RS03460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBR68_RS03465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CBR68_RS03470	COG0167	dihydroorotate dehydrogenase activity
CBR68_RS03485	COG1414	Transcriptional regulator
CBR68_RS03490	COG1058	Belongs to the CinA family
CBR68_RS03490	COG1546	Belongs to the CinA family
CBR68_RS03505	COG0513	Belongs to the DEAD box helicase family
CBR68_RS03530	COG0429	hydrolase of the alpha beta-hydrolase fold
CBR68_RS03535	COG4783	chaperone-mediated protein folding
CBR68_RS03555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBR68_RS03570	COG0006	proline dipeptidase activity
CBR68_RS03580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS03600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CBR68_RS03605	COG0632	four-way junction helicase activity
CBR68_RS03615	COG0702	epimerase
CBR68_RS03620	COG2255	four-way junction helicase activity
CBR68_RS03625	COG0514	ATP-dependent DNA helicase (RecQ)
CBR68_RS03645	COG1294	oxidase, subunit
CBR68_RS03655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR68_RS03660	COG0850	regulation of cytokinetic process
CBR68_RS03665	COG2894	cell division
CBR68_RS03670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBR68_RS03685	COG0488	(ABC) transporter
CBR68_RS03700	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS03705	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS03710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS03715	COG0601	transmembrane transport
CBR68_RS03725	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS03730	COG0583	DNA-binding transcription factor activity
CBR68_RS03735	COG1802	Transcriptional regulator
CBR68_RS03740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR68_RS03750	COG1024	Enoyl-CoA hydratase
CBR68_RS03775	COG1137	ATPase activity
CBR68_RS03785	COG0154	amidase activity
CBR68_RS03790	COG1368	sulfuric ester hydrolase activity
CBR68_RS03800	COG3685	Protein conserved in bacteria
CBR68_RS03810	COG1686	Belongs to the peptidase S11 family
CBR68_RS03830	COG2832	Protein of unknown function (DUF454)
CBR68_RS03845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR68_RS03875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBR68_RS03880	COG1802	Transcriptional regulator
CBR68_RS03885	COG0747	negative chemotaxis
CBR68_RS03890	COG0601	transmembrane transport
CBR68_RS03895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS03900	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS03905	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS03915	COG0745	RESPONSE REGULATOR receiver
CBR68_RS03915	COG2205	protein histidine kinase activity
CBR68_RS03915	COG4191	Histidine kinase
CBR68_RS03920	COG4566	intracellular signal transduction
CBR68_RS03945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR68_RS03950	COG0477	Major facilitator Superfamily
CBR68_RS03955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS03965	COG0583	DNA-binding transcription factor activity
CBR68_RS03970	COG1414	Transcriptional regulator
CBR68_RS03975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS03980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR68_RS03985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR68_RS03990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR68_RS03995	COG0583	DNA-binding transcription factor activity
CBR68_RS04000	COG3485	protocatechuate 3,4-dioxygenase
CBR68_RS04005	COG3485	protocatechuate 3,4-dioxygenase
CBR68_RS04015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR68_RS04035	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS04065	COG0683	leucine binding
CBR68_RS04090	COG0028	Belongs to the TPP enzyme family
CBR68_RS04095	COG1802	Transcriptional regulator
CBR68_RS04100	COG1802	Transcriptional regulator
CBR68_RS04105	COG0513	Belongs to the DEAD box helicase family
CBR68_RS04115	COG1595	DNA-templated transcription, initiation
CBR68_RS04125	COG0583	DNA-binding transcription factor activity
CBR68_RS04140	COG4774	siderophore transport
CBR68_RS04150	COG1595	DNA-templated transcription, initiation
CBR68_RS04165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS04190	COG0657	acetylesterase activity
CBR68_RS04200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR68_RS04205	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CBR68_RS04215	COG3971	2-oxopent-4-enoate hydratase activity
CBR68_RS04250	COG0459	protein refolding
CBR68_RS04265	COG0583	DNA-binding transcription factor activity
CBR68_RS04275	COG1073	alpha beta
CBR68_RS04275	COG2226	methyltransferase
CBR68_RS04300	COG1175	transmembrane transport
CBR68_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS04330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBR68_RS04360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBR68_RS04400	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBR68_RS04405	COG0459	protein refolding
CBR68_RS04415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBR68_RS04420	COG1252	NADH dehydrogenase
CBR68_RS04425	COG0284	orotidine-5'-phosphate decarboxylase activity
CBR68_RS04435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBR68_RS04445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR68_RS04450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBR68_RS04525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR68_RS04530	COG3639	organic phosphonate transmembrane transporter activity
CBR68_RS04535	COG3639	organic phosphonate transmembrane transporter activity
CBR68_RS04550	COG0742	ribosomal rna small subunit methyltransferase
CBR68_RS04555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBR68_RS04560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBR68_RS04565	COG3135	benzoate transporter
CBR68_RS04605	COG2188	Transcriptional regulator
CBR68_RS04610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS04615	COG1024	Enoyl-CoA hydratase
CBR68_RS04620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR68_RS04640	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS04645	COG2814	Major facilitator Superfamily
CBR68_RS04695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBR68_RS04700	COG1205	dead DEAH box helicase
CBR68_RS04700	COG1111	helicase
CBR68_RS04710	COG0582	viral genome integration into host DNA
CBR68_RS04715	COG0012	GTP binding
CBR68_RS04725	COG0193	aminoacyl-tRNA hydrolase activity
CBR68_RS04730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBR68_RS04735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBR68_RS04745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBR68_RS04750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CBR68_RS04760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBR68_RS04770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS04785	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR68_RS04795	COG1368	sulfuric ester hydrolase activity
CBR68_RS04800	COG2186	Transcriptional regulator
CBR68_RS04805	COG5000	phosphorelay sensor kinase activity
CBR68_RS04805	COG5002	protein histidine kinase activity
CBR68_RS04810	COG0745	RESPONSE REGULATOR receiver
CBR68_RS04815	COG0277	FAD linked oxidase domain protein
CBR68_RS04830	COG0166	Belongs to the GPI family
CBR68_RS04835	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS04840	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS04855	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS04870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR68_RS04875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR68_RS04880	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CBR68_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR68_RS04905	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS04920	COG0747	negative chemotaxis
CBR68_RS04925	COG0601	transmembrane transport
CBR68_RS04930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS04935	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS04950	COG5339	Protein conserved in bacteria
CBR68_RS04955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR68_RS04955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR68_RS04960	COG0509	glycine decarboxylation via glycine cleavage system
CBR68_RS04965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CBR68_RS04975	COG0371	Dehydrogenase
CBR68_RS05000	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS05015	COG2081	HI0933 family
CBR68_RS05030	COG1214	PFAM Peptidase M22, glycoprotease
CBR68_RS05030	COG0456	acetyltransferase
CBR68_RS05035	COG0717	Belongs to the dCTP deaminase family
CBR68_RS05050	COG0489	protein tyrosine kinase activity
CBR68_RS05060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR68_RS05060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR68_RS05065	COG1054	Belongs to the UPF0176 family
CBR68_RS05090	COG3539	Fimbrial protein
CBR68_RS05095	COG0010	Belongs to the arginase family
CBR68_RS05110	COG3842	ATPase activity
CBR68_RS05115	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR68_RS05120	COG1177	transmembrane transport
CBR68_RS05145	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS05160	COG2084	Dehydrogenase
CBR68_RS05165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR68_RS05200	COG1073	alpha beta
CBR68_RS05200	COG2226	methyltransferase
CBR68_RS05220	COG2423	ornithine cyclodeaminase activity
CBR68_RS05235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS05265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS05270	COG0765	amino acid transport
CBR68_RS05275	COG0765	amino acid transport
CBR68_RS05285	COG0583	DNA-binding transcription factor activity
CBR68_RS05290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR68_RS05295	COG0625	glutathione transferase activity
CBR68_RS05315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR68_RS05320	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS05325	COG1309	transcriptional regulator
CBR68_RS05360	COG1309	transcriptional regulator
CBR68_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS05370	COG0583	DNA-binding transcription factor activity
CBR68_RS05375	COG2072	flavoprotein involved in K transport
CBR68_RS05420	COG0426	domain, Protein
CBR68_RS05420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR68_RS05425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR68_RS05430	COG0583	DNA-binding transcription factor activity
CBR68_RS05435	COG3386	PFAM SMP-30 Gluconolaconase
CBR68_RS05440	COG1024	Enoyl-CoA hydratase
CBR68_RS05450	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS05480	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS05490	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR68_RS05500	COG0583	DNA-binding transcription factor activity
CBR68_RS05525	COG3119	arylsulfatase activity
CBR68_RS05550	COG0277	FAD linked oxidase domain protein
CBR68_RS05555	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR68_RS05560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR68_RS05585	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS05590	COG0583	DNA-binding transcription factor activity
CBR68_RS05600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBR68_RS05615	COG1652	LysM domain
CBR68_RS05620	COG0560	Phosphoserine phosphatase
CBR68_RS05625	COG0583	DNA-binding transcription factor activity
CBR68_RS05630	COG3842	ATPase activity
CBR68_RS05635	COG1178	ABC-type Fe3 transport system permease component
CBR68_RS05645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBR68_RS05650	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR68_RS05665	COG0625	glutathione transferase activity
CBR68_RS05695	COG4336	lyase activity
CBR68_RS05705	COG1414	Transcriptional regulator
CBR68_RS05710	COG3734	2-keto-3-deoxy-galactonokinase
CBR68_RS05715	COG0800	Aldolase
CBR68_RS05720	COG4948	Mandelate Racemase Muconate Lactonizing
CBR68_RS05725	COG2271	Major facilitator Superfamily
CBR68_RS05730	COG0326	Molecular chaperone. Has ATPase activity
CBR68_RS05735	COG2233	PERMEase
CBR68_RS05760	COG1819	glycosyl
CBR68_RS05770	COG3284	Transcriptional regulator
CBR68_RS05795	COG0509	glycine decarboxylation via glycine cleavage system
CBR68_RS05800	COG0022	dehydrogenase e1 component
CBR68_RS05805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBR68_RS05820	COG0235	Class ii aldolase
CBR68_RS05830	COG0436	Aminotransferase
CBR68_RS05905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBR68_RS05910	COG4774	siderophore transport
CBR68_RS05915	COG3712	iron ion homeostasis
CBR68_RS05920	COG1595	DNA-templated transcription, initiation
CBR68_RS05925	COG5285	phytanoyl-CoA dioxygenase
CBR68_RS05930	COG0628	permease
CBR68_RS05935	COG0583	DNA-binding transcription factor activity
CBR68_RS05940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS05960	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CBR68_RS05970	COG3539	Fimbrial protein
CBR68_RS05975	COG0129	dihydroxy-acid dehydratase activity
CBR68_RS05995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBR68_RS06000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CBR68_RS06005	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS06010	COG2031	fatty acid transporter
CBR68_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS06020	COG1414	Transcriptional regulator
CBR68_RS06030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CBR68_RS06035	COG4829	muconolactone delta-isomerase
CBR68_RS06045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR68_RS06065	COG0288	reversible hydration of carbon dioxide
CBR68_RS06070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR68_RS06090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CBR68_RS06095	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR68_RS06100	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBR68_RS06105	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CBR68_RS06130	COG0659	secondary active sulfate transmembrane transporter activity
CBR68_RS06160	COG0683	leucine binding
CBR68_RS06165	COG0154	amidase activity
CBR68_RS06190	COG0142	geranyltranstransferase activity
CBR68_RS06195	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBR68_RS06200	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBR68_RS06205	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBR68_RS06210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CBR68_RS06230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR68_RS06230	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR68_RS06235	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBR68_RS06250	COG0861	Integral membrane protein TerC family
CBR68_RS06255	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS06270	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBR68_RS06275	COG0793	Belongs to the peptidase S41A family
CBR68_RS06280	COG4942	peptidase
CBR68_RS06285	COG0588	phosphoglycerate mutase activity
CBR68_RS06295	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR68_RS06300	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBR68_RS06305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBR68_RS06325	COG2226	methyltransferase
CBR68_RS06330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CBR68_RS06335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CBR68_RS06340	COG0569	domain protein
CBR68_RS06345	COG2204	response regulator
CBR68_RS06350	COG5000	phosphorelay sensor kinase activity
CBR68_RS06360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR68_RS06360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR68_RS06370	COG0583	DNA-binding transcription factor activity
CBR68_RS06375	COG2814	Major facilitator Superfamily
CBR68_RS06380	COG0583	DNA-binding transcription factor activity
CBR68_RS06390	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR68_RS06395	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS06400	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS06405	COG2072	flavoprotein involved in K transport
CBR68_RS06410	COG2267	carboxylic ester hydrolase activity
CBR68_RS06440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR68_RS06445	COG0583	DNA-binding transcription factor activity
CBR68_RS06450	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS06480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS06485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR68_RS06500	COG0546	phosphoglycolate phosphatase activity
CBR68_RS06510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR68_RS06515	COG0242	peptide deformylase activity
CBR68_RS06525	COG1522	sequence-specific DNA binding
CBR68_RS06530	COG2879	small protein
CBR68_RS06535	COG1966	Carbon starvation protein
CBR68_RS06550	COG0758	DNA mediated transformation
CBR68_RS06565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS06570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR68_RS06575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBR68_RS06645	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS06680	COG0640	Transcriptional regulator
CBR68_RS06715	COG0735	belongs to the Fur family
CBR68_RS06720	COG2207	Transcriptional regulator
CBR68_RS06735	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR68_RS06740	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBR68_RS06745	COG0513	Belongs to the DEAD box helicase family
CBR68_RS06765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBR68_RS06770	COG2308	Evidence 4 Homologs of previously reported genes of
CBR68_RS06780	COG1305	Transglutaminase-like
CBR68_RS06800	COG3220	belongs to the UPF0276 family
CBR68_RS06815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBR68_RS06820	COG1950	PFAM Membrane protein of
CBR68_RS06830	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS06845	COG0066	3-isopropylmalate dehydratase activity
CBR68_RS06860	COG0583	DNA-binding transcription factor activity
CBR68_RS06865	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBR68_RS06875	COG1560	Kdo2-lipid A biosynthetic process
CBR68_RS06880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBR68_RS06890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CBR68_RS06915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBR68_RS06925	COG0735	belongs to the Fur family
CBR68_RS06930	COG0523	cobalamin synthesis protein
CBR68_RS06940	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBR68_RS06945	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBR68_RS06955	COG2096	Adenosyltransferase
CBR68_RS06960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CBR68_RS06965	COG0321	lipoyl(octanoyl) transferase activity
CBR68_RS06970	COG2921	Belongs to the UPF0250 family
CBR68_RS06980	COG1686	Belongs to the peptidase S11 family
CBR68_RS07000	COG1127	ABC transporter
CBR68_RS07005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR68_RS07015	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBR68_RS07025	COG0859	PFAM glycosyl transferase family 9
CBR68_RS07060	COG0477	Major facilitator Superfamily
CBR68_RS07070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR68_RS07075	COG3568	Endonuclease Exonuclease Phosphatase
CBR68_RS07080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBR68_RS07110	COG0531	amino acid
CBR68_RS07115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR68_RS07120	COG1956	GAF domain-containing protein
CBR68_RS07125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR68_RS07130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CBR68_RS07140	COG1129	ABC transporter
CBR68_RS07150	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS07160	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS07170	COG2186	Transcriptional regulator
CBR68_RS07175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CBR68_RS07180	COG3842	ATPase activity
CBR68_RS07185	COG1175	transmembrane transport
CBR68_RS07235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBR68_RS07240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR68_RS07260	COG0367	asparagine synthase
CBR68_RS07280	COG0367	asparagine synthase
CBR68_RS07290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR68_RS07320	COG0367	asparagine synthase
CBR68_RS07335	COG2814	Major facilitator Superfamily
CBR68_RS07355	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CBR68_RS07360	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBR68_RS07365	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR68_RS07375	COG1965	Belongs to the frataxin family
CBR68_RS07390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR68_RS07395	COG1333	cytochrome c biogenesis protein
CBR68_RS07405	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBR68_RS07420	COG4232	protein-disulfide reductase activity
CBR68_RS07425	COG1324	tolerance protein
CBR68_RS07435	COG0203	ribosomal protein L17
CBR68_RS07440	COG0202	RNA polymerase activity
CBR68_RS07445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBR68_RS07450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBR68_RS07455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBR68_RS07460	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBR68_RS07465	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR68_RS07470	COG0201	protein transport
CBR68_RS07475	COG0200	Binds to the 23S rRNA
CBR68_RS07480	COG1841	ribosomal large subunit assembly
CBR68_RS07485	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBR68_RS07490	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBR68_RS07495	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBR68_RS07500	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBR68_RS07505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBR68_RS07510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBR68_RS07515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBR68_RS07520	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBR68_RS07545	COG2267	carboxylic ester hydrolase activity
CBR68_RS07560	COG1131	(ABC) transporter
CBR68_RS07575	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBR68_RS07580	COG0255	Belongs to the universal ribosomal protein uL29 family
CBR68_RS07585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBR68_RS07590	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBR68_RS07595	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBR68_RS07600	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBR68_RS07605	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBR68_RS07610	COG0089	rRNA binding
CBR68_RS07615	COG0088	Forms part of the polypeptide exit tunnel
CBR68_RS07620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBR68_RS07625	COG0051	transcription antitermination factor activity, RNA binding
CBR68_RS07630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR68_RS07635	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR68_RS07640	COG0049	tRNA binding
CBR68_RS07645	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBR68_RS07680	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBR68_RS07685	COG0085	RNA polymerase activity
CBR68_RS07690	COG0222	ribosome binding
CBR68_RS07695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBR68_RS07700	COG0081	regulation of translation
CBR68_RS07705	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBR68_RS07715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR68_RS07725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR68_RS07745	COG0252	asparaginase activity
CBR68_RS07750	COG1475	DNA binding
CBR68_RS07755	COG1192	Involved in chromosome partitioning
CBR68_RS07760	COG0357	Ribosomal RNA small subunit methyltransferase G
CBR68_RS07765	COG0445	tRNA wobble uridine modification
CBR68_RS07770	COG1278	Cold shock
CBR68_RS07775	COG0436	Aminotransferase
CBR68_RS07785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR68_RS07790	COG0583	DNA-binding transcription factor activity
CBR68_RS07840	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS07845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS07855	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR68_RS07865	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR68_RS07875	COG1505	serine-type exopeptidase activity
CBR68_RS07880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR68_RS07890	COG0601	transmembrane transport
CBR68_RS07895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS07900	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS07905	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS07910	COG1473	amidohydrolase
CBR68_RS07915	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CBR68_RS07920	COG0706	membrane insertase activity
CBR68_RS07925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBR68_RS07930	COG0594	ribonuclease P activity
CBR68_RS07935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBR68_RS07940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBR68_RS07945	COG0592	DNA-directed DNA polymerase activity
CBR68_RS07960	COG1309	transcriptional regulator
CBR68_RS07965	COG1254	Belongs to the acylphosphatase family
CBR68_RS07970	COG1304	FMN binding
CBR68_RS07975	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CBR68_RS07990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS07995	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS08020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS08030	COG0625	glutathione transferase activity
CBR68_RS08035	COG0402	S-adenosylhomocysteine deaminase activity
CBR68_RS08040	COG1079	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS08045	COG4603	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS08050	COG3845	ABC transporter
CBR68_RS08065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR68_RS08070	COG2910	NAD(P)H-binding
CBR68_RS08090	COG0702	epimerase
CBR68_RS08100	COG3781	membrane
CBR68_RS08105	COG1522	sequence-specific DNA binding
CBR68_RS08110	COG0028	Belongs to the TPP enzyme family
CBR68_RS08120	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS08125	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS08130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR68_RS08135	COG3842	ATPase activity
CBR68_RS08155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR68_RS08160	COG2922	Belongs to the Smg family
CBR68_RS08165	COG1629	transport
CBR68_RS08175	COG2358	TRAP transporter, solute receptor (TAXI family
CBR68_RS08185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR68_RS08200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CBR68_RS08205	COG0183	Belongs to the thiolase family
CBR68_RS08210	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS08215	COG1473	amidohydrolase
CBR68_RS08245	COG2200	EAL domain
CBR68_RS08250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR68_RS08260	COG0018	arginyl-trna synthetase
CBR68_RS08275	COG0395	ABC-type sugar transport system, permease component
CBR68_RS08280	COG1175	transmembrane transport
CBR68_RS08285	COG1653	transport
CBR68_RS08290	COG3842	ATPase activity
CBR68_RS08295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR68_RS08300	COG3842	ATPase activity
CBR68_RS08325	COG0154	amidase activity
CBR68_RS08330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR68_RS08340	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR68_RS08350	COG0583	DNA-binding transcription factor activity
CBR68_RS08370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBR68_RS08375	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS08380	COG0513	Belongs to the DEAD box helicase family
CBR68_RS08390	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CBR68_RS08400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS08405	COG0601	transmembrane transport
CBR68_RS08415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR68_RS08435	COG0697	spore germination
CBR68_RS08450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR68_RS08460	COG2969	positive regulation of protein catabolic process
CBR68_RS08465	COG0625	glutathione transferase activity
CBR68_RS08470	COG2857	Cytochrome c1
CBR68_RS08475	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBR68_RS08480	COG0723	plastoquinol--plastocyanin reductase activity
CBR68_RS08485	COG1970	mechanosensitive ion channel activity
CBR68_RS08490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBR68_RS08495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR68_RS08505	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR68_RS08510	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR68_RS08515	COG0537	adenosine 5'-monophosphoramidase activity
CBR68_RS08520	COG0140	phosphoribosyl-ATP diphosphatase activity
CBR68_RS08525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBR68_RS08530	COG0107	imidazoleglycerol-phosphate synthase activity
CBR68_RS08535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBR68_RS08545	COG0131	Imidazoleglycerol-phosphate dehydratase
CBR68_RS08550	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR68_RS08555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBR68_RS08560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBR68_RS08565	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBR68_RS08575	COG0842	Transport permease protein
CBR68_RS08580	COG1131	(ABC) transporter
CBR68_RS08595	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CBR68_RS08600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR68_RS08605	COG1127	ABC transporter
CBR68_RS08610	COG3047	cAMP biosynthetic process
CBR68_RS08620	COG0069	glutamate synthase activity
CBR68_RS08620	COG0070	glutamate synthase
CBR68_RS08620	COG0067	glutamate synthase
CBR68_RS08635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CBR68_RS08650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBR68_RS08655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR68_RS08665	COG1609	Transcriptional regulator
CBR68_RS08670	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CBR68_RS08680	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR68_RS08720	COG0109	protoheme IX farnesyltransferase activity
CBR68_RS08725	COG1999	signal sequence binding
CBR68_RS08745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR68_RS08750	COG2814	Major facilitator Superfamily
CBR68_RS08765	COG1522	sequence-specific DNA binding
CBR68_RS08860	COG2124	cytochrome p450
CBR68_RS08895	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS08905	COG1902	pentaerythritol trinitrate reductase activity
CBR68_RS08980	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR68_RS08990	COG1671	Belongs to the UPF0178 family
CBR68_RS08995	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS09020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBR68_RS09025	COG0443	Heat shock 70 kDa protein
CBR68_RS09035	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS09060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBR68_RS09060	COG2169	Transcriptional regulator
CBR68_RS09075	COG0583	DNA-binding transcription factor activity
CBR68_RS09085	COG1473	amidohydrolase
CBR68_RS09090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR68_RS09095	COG1335	isochorismatase
CBR68_RS09105	COG1683	Conserved Protein
CBR68_RS09110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS09125	COG1120	ATPase activity
CBR68_RS09130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR68_RS09135	COG4558	Periplasmic binding protein
CBR68_RS09140	COG3720	iron ion transport
CBR68_RS09150	COG3712	iron ion homeostasis
CBR68_RS09155	COG1595	DNA-templated transcription, initiation
CBR68_RS09185	COG1607	acyl-coa hydrolase
CBR68_RS09200	COG0437	4 iron, 4 sulfur cluster binding
CBR68_RS09205	COG2864	formate dehydrogenase
CBR68_RS09220	COG3276	selenocysteine insertion sequence binding
CBR68_RS09240	COG0583	DNA-binding transcription factor activity
CBR68_RS09250	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS09260	COG0134	indole-3-glycerol-phosphate synthase activity
CBR68_RS09265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBR68_RS09270	COG0512	Glutamine amidotransferase of anthranilate synthase
CBR68_RS09280	COG0546	phosphoglycolate phosphatase activity
CBR68_RS09285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBR68_RS09290	COG2967	ApaG domain
CBR68_RS09295	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CBR68_RS09300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS09305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR68_RS09315	COG0037	tRNA processing
CBR68_RS09335	COG1024	Enoyl-CoA hydratase
CBR68_RS09350	COG0356	it plays a direct role in the translocation of protons across the membrane
CBR68_RS09360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBR68_RS09365	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBR68_RS09370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBR68_RS09375	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBR68_RS09380	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBR68_RS09385	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBR68_RS09395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBR68_RS09400	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBR68_RS09405	COG0210	DNA helicase
CBR68_RS09420	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS09425	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS09430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS09435	COG0601	transmembrane transport
CBR68_RS09445	COG0747	negative chemotaxis
CBR68_RS09455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBR68_RS09460	COG1024	Enoyl-CoA hydratase
CBR68_RS09465	COG1024	Enoyl-CoA hydratase
CBR68_RS09470	COG2070	2-Nitropropane dioxygenase
CBR68_RS09475	COG1309	transcriptional regulator
CBR68_RS09480	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS09490	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS09495	COG3245	cytochrome
CBR68_RS09520	COG2918	glutathione biosynthetic process
CBR68_RS09540	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR68_RS09545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR68_RS09550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR68_RS09550	COG2813	Specifically methylates the guanine in position
CBR68_RS09555	COG2223	nitrite transmembrane transporter activity
CBR68_RS09560	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS09570	COG2860	membrane
CBR68_RS09575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR68_RS09580	COG0708	Exodeoxyribonuclease III
CBR68_RS09585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBR68_RS09590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR68_RS09595	COG0154	amidase activity
CBR68_RS09600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR68_RS09605	COG1077	Cell shape determining protein MreB Mrl
CBR68_RS09610	COG1792	Involved in formation and maintenance of cell shape
CBR68_RS09620	COG0768	penicillin binding
CBR68_RS09625	COG0772	Belongs to the SEDS family
CBR68_RS09630	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR68_RS09635	COG0471	metal ion transport
CBR68_RS09640	COG1309	transcriptional regulator
CBR68_RS09650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR68_RS09665	COG2823	Periplasmic or secreted lipoprotein
CBR68_RS09670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CBR68_RS09675	COG0792	nuclease activity
CBR68_RS09695	COG1660	Displays ATPase and GTPase activities
CBR68_RS09710	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CBR68_RS09720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBR68_RS09725	COG1137	ATPase activity
CBR68_RS09740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CBR68_RS09750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CBR68_RS09765	COG1294	oxidase, subunit
CBR68_RS09775	COG4988	ABC transporter
CBR68_RS09780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBR68_RS09785	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR68_RS09800	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS09805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR68_RS09810	COG1238	metal cluster binding
CBR68_RS09820	COG1802	Transcriptional regulator
CBR68_RS09830	COG1984	allophanate hydrolase subunit 2
CBR68_RS09835	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CBR68_RS09850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR68_RS09865	COG2132	Multicopper oxidase
CBR68_RS09875	COG5002	protein histidine kinase activity
CBR68_RS09885	COG5002	protein histidine kinase activity
CBR68_RS09890	COG0745	RESPONSE REGULATOR receiver
CBR68_RS09895	COG2226	methyltransferase
CBR68_RS09910	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR68_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS09950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR68_RS09985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR68_RS10000	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBR68_RS10010	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBR68_RS10015	COG1538	Outer membrane efflux protein
CBR68_RS10020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR68_RS10025	COG0351	phosphomethylpyrimidine kinase
CBR68_RS10030	COG2022	thiamine diphosphate biosynthetic process
CBR68_RS10040	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBR68_RS10045	COG4206	TonB-dependent receptor
CBR68_RS10055	COG2226	methyltransferase
CBR68_RS10070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR68_RS10085	COG1194	a g-specific adenine glycosylase
CBR68_RS10095	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CBR68_RS10100	COG2177	Part of the ABC transporter FtsEX involved in
CBR68_RS10105	COG2884	Cell division ATP-binding protein ftsE
CBR68_RS10110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS10115	COG4597	amino acid ABC transporter
CBR68_RS10120	COG0765	amino acid transport
CBR68_RS10125	COG1126	abc transporter atp-binding protein
CBR68_RS10145	COG0477	Major facilitator Superfamily
CBR68_RS10155	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CBR68_RS10160	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBR68_RS10175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBR68_RS10180	COG0237	dephospho-CoA kinase activity
CBR68_RS10185	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CBR68_RS10210	COG3539	Fimbrial protein
CBR68_RS10215	COG2816	NAD+ diphosphatase activity
CBR68_RS10225	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBR68_RS10260	COG0411	ABC transporter
CBR68_RS10295	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS10300	COG1024	Enoyl-CoA hydratase
CBR68_RS10330	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR68_RS10335	COG0352	thiamine-phosphate diphosphorylase activity
CBR68_RS10350	COG1678	Uncharacterized ACR, COG1678
CBR68_RS10355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBR68_RS10380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR68_RS10390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBR68_RS10395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBR68_RS10405	COG0557	exoribonuclease II activity
CBR68_RS10410	COG3150	esterase
CBR68_RS10415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR68_RS10420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR68_RS10425	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR68_RS10430	COG0511	ligase activity, forming carbon-carbon bonds
CBR68_RS10435	COG0439	Biotin carboxylase
CBR68_RS10440	COG2264	protein methyltransferase activity
CBR68_RS10450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBR68_RS10475	COG1696	Membrane protein involved in D-alanine export
CBR68_RS10480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR68_RS10510	COG1522	sequence-specific DNA binding
CBR68_RS10520	COG2814	Major facilitator Superfamily
CBR68_RS10525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR68_RS10530	COG1042	CoA-binding domain protein
CBR68_RS10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR68_RS10530	COG1042	CoA-binding domain protein
CBR68_RS10530	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR68_RS10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR68_RS10530	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR68_RS10580	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR68_RS10605	COG3028	Belongs to the UPF0307 family
CBR68_RS10610	COG0312	modulator of DNA gyrase
CBR68_RS10620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR68_RS10625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBR68_RS10630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBR68_RS10635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR68_RS10645	COG0316	Belongs to the HesB IscA family
CBR68_RS10650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CBR68_RS10660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBR68_RS10670	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBR68_RS10675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBR68_RS10685	COG1335	isochorismatase
CBR68_RS10690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR68_RS10690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR68_RS10700	COG2766	serine protein kinase
CBR68_RS10705	COG2718	Belongs to the UPF0229 family
CBR68_RS10710	COG2719	SpoVR family
CBR68_RS10730	COG4948	Mandelate Racemase Muconate Lactonizing
CBR68_RS10745	COG0477	Major facilitator Superfamily
CBR68_RS10755	COG0583	DNA-binding transcription factor activity
CBR68_RS10770	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR68_RS10775	COG0251	oxidation-reduction process
CBR68_RS10780	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CBR68_RS10785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CBR68_RS10800	COG0165	Argininosuccinate lyase
CBR68_RS10810	COG3707	response regulator
CBR68_RS10820	COG0515	serine threonine protein kinase
CBR68_RS10825	COG2116	formate transmembrane transporter activity
CBR68_RS10835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBR68_RS10835	COG2146	nitrite reductase [NAD(P)H] activity
CBR68_RS10840	COG0589	response to stress
CBR68_RS10855	COG2816	NAD+ diphosphatase activity
CBR68_RS10860	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS10900	COG2979	Protein of unknown function (DUF533)
CBR68_RS10910	COG1388	LysM domain
CBR68_RS10910	COG0741	lytic transglycosylase activity
CBR68_RS10915	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBR68_RS10920	COG2226	methyltransferase
CBR68_RS10925	COG0328	RNA-DNA hybrid ribonuclease activity
CBR68_RS10935	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR68_RS10940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBR68_RS10950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS10955	COG1129	ABC transporter
CBR68_RS10955	COG0842	Transport permease protein
CBR68_RS10960	COG0842	Transport permease protein
CBR68_RS10980	COG0463	Glycosyl transferase, family 2
CBR68_RS10985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBR68_RS11000	COG1073	alpha beta
CBR68_RS11010	COG0697	spore germination
CBR68_RS11015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR68_RS11030	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR68_RS11040	COG1522	sequence-specific DNA binding
CBR68_RS11065	COG0823	Involved in the tonB-independent uptake of proteins
CBR68_RS11075	COG0848	biopolymer transport protein
CBR68_RS11080	COG0811	peptide transport
CBR68_RS11085	COG0824	Thioesterase
CBR68_RS11090	COG0442	prolyl-tRNA aminoacylation
CBR68_RS11120	COG1414	Transcriptional regulator
CBR68_RS11125	COG1024	Enoyl-CoA hydratase
CBR68_RS11140	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBR68_RS11145	COG2084	Dehydrogenase
CBR68_RS11150	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS11155	COG1309	transcriptional regulator
CBR68_RS11190	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBR68_RS11195	COG4654	Cytochrome c, class I
CBR68_RS11200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR68_RS11250	COG1473	amidohydrolase
CBR68_RS11255	COG0418	dihydroorotase activity
CBR68_RS11260	COG0488	(ABC) transporter
CBR68_RS11270	COG2001	Belongs to the MraZ family
CBR68_RS11275	COG0275	rRNA processing
CBR68_RS11280	COG3116	cell division
CBR68_RS11290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR68_RS11295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR68_RS11300	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBR68_RS11310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBR68_RS11315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR68_RS11320	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBR68_RS11325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBR68_RS11340	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBR68_RS11355	COG0739	heme binding
CBR68_RS11360	COG0653	protein targeting
CBR68_RS11385	COG1522	sequence-specific DNA binding
CBR68_RS11400	COG2239	Acts as a magnesium transporter
CBR68_RS11410	COG2855	membrane
CBR68_RS11415	COG0583	DNA-binding transcription factor activity
CBR68_RS11420	COG1473	amidohydrolase
CBR68_RS11425	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS11435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR68_RS11435	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CBR68_RS11440	COG1501	Belongs to the glycosyl hydrolase 31 family
CBR68_RS11445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBR68_RS11450	COG2011	ABC-type metal ion transport system permease component
CBR68_RS11465	COG0300	oxidoreductase activity
CBR68_RS11485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CBR68_RS11490	COG0156	8-amino-7-oxononanoate synthase activity
CBR68_RS11495	COG3321	synthase
CBR68_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS11495	COG0604	alcohol dehydrogenase
CBR68_RS11500	COG0402	S-adenosylhomocysteine deaminase activity
CBR68_RS11525	COG0727	PFAM Uncharacterised protein family (UPF0153)
CBR68_RS11530	COG2818	Glycosylase
CBR68_RS11535	COG2982	Protein involved in outer membrane biogenesis
CBR68_RS11565	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CBR68_RS11570	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR68_RS11605	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS11610	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS11615	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS11620	COG1024	Enoyl-CoA hydratase
CBR68_RS11625	COG1024	Enoyl-CoA hydratase
CBR68_RS11640	COG2197	response regulator
CBR68_RS11655	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS11670	COG0410	ABC transporter
CBR68_RS11690	COG0583	DNA-binding transcription factor activity
CBR68_RS11695	COG0737	Belongs to the 5'-nucleotidase family
CBR68_RS11705	COG4106	trans-aconitate 2-methyltransferase activity
CBR68_RS11710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR68_RS11720	COG0667	Aldo Keto reductase
CBR68_RS11735	COG2154	pterin-4-alpha-carbinolamine dehydratase
CBR68_RS11745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CBR68_RS11755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CBR68_RS11760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR68_RS11765	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBR68_RS11775	COG1929	Belongs to the glycerate kinase type-1 family
CBR68_RS11780	COG0469	pyruvate kinase activity
CBR68_RS11785	COG0700	Nucleoside recognition
CBR68_RS11790	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS11795	COG0242	peptide deformylase activity
CBR68_RS11815	COG3976	FMN-binding domain protein
CBR68_RS11815	COG1053	succinate dehydrogenase
CBR68_RS11820	COG0583	DNA-binding transcription factor activity
CBR68_RS11830	COG0204	Acyl-transferase
CBR68_RS11835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR68_RS11840	COG0751	glycine-tRNA ligase activity
CBR68_RS11845	COG0752	glycyl-tRNA synthetase alpha subunit
CBR68_RS11850	COG1024	Enoyl-CoA hydratase
CBR68_RS11860	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CBR68_RS11890	COG0617	tRNA 3'-terminal CCA addition
CBR68_RS11905	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBR68_RS11910	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBR68_RS11915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBR68_RS11920	COG0586	Pfam SNARE associated Golgi protein
CBR68_RS11925	COG3064	Membrane
CBR68_RS11925	COG3210	domain, Protein
CBR68_RS11925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR68_RS11925	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR68_RS11925	COG3210	domain, Protein
CBR68_RS11925	COG3064	Membrane
CBR68_RS11930	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBR68_RS11940	COG0114	fumarate hydratase activity
CBR68_RS11950	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS11960	COG0405	Gamma-glutamyltransferase
CBR68_RS11970	COG3210	domain, Protein
CBR68_RS11980	COG0579	oxidoreductase
CBR68_RS11985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR68_RS11990	COG0259	pyridoxamine-phosphate oxidase activity
CBR68_RS12005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS12010	COG0577	efflux transmembrane transporter activity
CBR68_RS12010	COG1136	(ABC) transporter
CBR68_RS12015	COG1538	Outer membrane efflux protein
CBR68_RS12020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBR68_RS12030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR68_RS12055	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBR68_RS12080	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS12145	COG0583	DNA-binding transcription factor activity
CBR68_RS12170	COG0427	acetyl-CoA hydrolase
CBR68_RS12175	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS12180	COG2301	Belongs to the HpcH HpaI aldolase family
CBR68_RS12210	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS12215	COG0683	leucine binding
CBR68_RS12225	COG2205	protein histidine kinase activity
CBR68_RS12230	COG3210	domain, Protein
CBR68_RS12240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS12245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR68_RS12250	COG1538	Outer membrane efflux protein
CBR68_RS12270	COG3258	Cytochrome c
CBR68_RS12275	COG2863	cytochrome
CBR68_RS12295	COG2205	protein histidine kinase activity
CBR68_RS12310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS12315	COG2301	Belongs to the HpcH HpaI aldolase family
CBR68_RS12330	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS12340	COG2814	Major facilitator Superfamily
CBR68_RS12355	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS12360	COG4948	Mandelate Racemase Muconate Lactonizing
CBR68_RS12365	COG0583	DNA-binding transcription factor activity
CBR68_RS12410	COG3585	molybdate ion transport
CBR68_RS12415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR68_RS12425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR68_RS12430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR68_RS12445	COG2188	Transcriptional regulator
CBR68_RS12450	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR68_RS12460	COG0402	S-adenosylhomocysteine deaminase activity
CBR68_RS12465	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBR68_RS12470	COG0022	dehydrogenase e1 component
CBR68_RS12470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR68_RS12475	COG1024	Enoyl-CoA hydratase
CBR68_RS12480	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR68_RS12490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR68_RS12520	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS12525	COG0411	ABC transporter
CBR68_RS12550	COG1309	transcriptional regulator
CBR68_RS12565	COG1024	Enoyl-CoA hydratase
CBR68_RS12585	COG4133	protoheme IX ABC transporter activity
CBR68_RS12590	COG0154	amidase activity
CBR68_RS12600	COG0583	DNA-binding transcription factor activity
CBR68_RS12620	COG2197	response regulator
CBR68_RS12625	COG2814	Major facilitator Superfamily
CBR68_RS12635	COG4774	siderophore transport
CBR68_RS12640	COG3712	iron ion homeostasis
CBR68_RS12645	COG1595	DNA-templated transcription, initiation
CBR68_RS12685	COG0625	glutathione transferase activity
CBR68_RS12695	COG0747	negative chemotaxis
CBR68_RS12700	COG0583	DNA-binding transcription factor activity
CBR68_RS12735	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS12740	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS12745	COG2207	Transcriptional regulator
CBR68_RS12750	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS12765	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS12770	COG3284	Transcriptional regulator
CBR68_RS12780	COG2814	Major facilitator Superfamily
CBR68_RS12785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR68_RS12795	COG1959	2 iron, 2 sulfur cluster binding
CBR68_RS12805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR68_RS12810	COG1971	Probably functions as a manganese efflux pump
CBR68_RS12825	COG1360	Flagellar Motor Protein
CBR68_RS12840	COG0840	transmembrane signaling receptor activity
CBR68_RS12860	COG5265	(ABC) transporter
CBR68_RS12875	COG0833	amino acid
CBR68_RS12905	COG0235	Class ii aldolase
CBR68_RS12915	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR68_RS12920	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS12925	COG2186	Transcriptional regulator
CBR68_RS12930	COG1024	Enoyl-CoA hydratase
CBR68_RS12945	COG0583	DNA-binding transcription factor activity
CBR68_RS12955	COG2159	amidohydrolase
CBR68_RS12970	COG1301	dicarboxylic acid transport
CBR68_RS12980	COG0148	phosphopyruvate hydratase activity
CBR68_RS12990	COG2814	Major facilitator Superfamily
CBR68_RS12995	COG0583	DNA-binding transcription factor activity
CBR68_RS13040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR68_RS13050	COG4774	siderophore transport
CBR68_RS13060	COG3128	pkhd-type hydroxylase
CBR68_RS13075	COG3064	Membrane
CBR68_RS13080	COG1408	metallophosphoesterase
CBR68_RS13090	COG0456	acetyltransferase
CBR68_RS13100	COG2610	gluconate transmembrane transporter activity
CBR68_RS13110	COG2070	2-Nitropropane dioxygenase
CBR68_RS13120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CBR68_RS13165	COG1846	Transcriptional regulator
CBR68_RS13180	COG5001	Diguanylate cyclase
CBR68_RS13180	COG3300	MHYT domain
CBR68_RS13210	COG4964	Belongs to the GSP D family
CBR68_RS13265	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS13270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBR68_RS13285	COG3384	dioxygenase
CBR68_RS13290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR68_RS13310	COG2176	DNA-directed DNA polymerase activity
CBR68_RS13335	COG4221	oxidoreductase activity
CBR68_RS13345	COG1511	domain protein
CBR68_RS13345	COG3264	Mechanosensitive ion channel
CBR68_RS13350	COG0583	DNA-binding transcription factor activity
CBR68_RS13355	COG0427	acetyl-CoA hydrolase
CBR68_RS13360	COG0583	DNA-binding transcription factor activity
CBR68_RS13410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS13425	COG0154	amidase activity
CBR68_RS13440	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBR68_RS13455	COG0495	leucyl-tRNA aminoacylation
CBR68_RS13460	COG2814	Major facilitator Superfamily
CBR68_RS13465	COG1846	Transcriptional regulator
CBR68_RS13485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBR68_RS13490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBR68_RS13495	COG2814	Major facilitator Superfamily
CBR68_RS13500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBR68_RS13510	COG4176	ABC-type proline glycine betaine transport system permease component
CBR68_RS13525	COG0183	Belongs to the thiolase family
CBR68_RS13545	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR68_RS13545	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR68_RS13555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR68_RS13560	COG1845	cytochrome c oxidase, subunit III
CBR68_RS13565	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR68_RS13570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CBR68_RS13575	COG0477	Major facilitator Superfamily
CBR68_RS13580	COG0428	transporter
CBR68_RS13585	COG0412	Dienelactone hydrolase
CBR68_RS13590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR68_RS13595	COG1283	sodium-dependent phosphate transmembrane transporter activity
CBR68_RS13600	COG1760	l-serine dehydratase
CBR68_RS13605	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBR68_RS13610	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CBR68_RS13620	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBR68_RS13645	COG2311	Membrane
CBR68_RS13655	COG2358	TRAP transporter, solute receptor (TAXI family
CBR68_RS13660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS13675	COG0456	acetyltransferase
CBR68_RS13685	COG0662	Cupin 2, conserved barrel domain protein
CBR68_RS13690	COG5285	phytanoyl-CoA dioxygenase
CBR68_RS13700	COG3217	Mosc domain protein beta barrel domain protein
CBR68_RS13700	COG0633	Ferredoxin
CBR68_RS13705	COG2076	Multidrug Resistance protein
CBR68_RS13710	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBR68_RS13715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR68_RS13715	COG0543	2 iron, 2 sulfur cluster binding
CBR68_RS13720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR68_RS13770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR68_RS13775	COG0425	Belongs to the sulfur carrier protein TusA family
CBR68_RS13785	COG0228	four-way junction DNA binding
CBR68_RS13790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBR68_RS13795	COG0336	Belongs to the RNA methyltransferase TrmD family
CBR68_RS13800	COG0525	valine-tRNA ligase activity
CBR68_RS13805	COG0105	UTP biosynthetic process
CBR68_RS13810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR68_RS13825	COG0124	histidyl-tRNA synthetase
CBR68_RS13830	COG2976	Protein conserved in bacteria
CBR68_RS13835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR68_RS13840	COG1160	GTP binding
CBR68_RS13845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR68_RS13850	COG1923	regulation of RNA biosynthetic process
CBR68_RS13855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBR68_RS13860	COG0330	HflC and HflK could
CBR68_RS13865	COG0330	HflC and HflK could
CBR68_RS13870	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBR68_RS13875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBR68_RS13885	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBR68_RS13935	COG2207	Transcriptional regulator
CBR68_RS13945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBR68_RS13945	COG0475	glutathione-regulated potassium exporter activity
CBR68_RS13965	COG0330	HflC and HflK could
CBR68_RS13980	COG0840	transmembrane signaling receptor activity
CBR68_RS14005	COG2201	protein-glutamate methylesterase activity
CBR68_RS14010	COG2203	Gaf domain
CBR68_RS14010	COG3706	GGDEF domain
CBR68_RS14010	COG4251	negative regulation of phosphorylation
CBR68_RS14010	COG5001	Diguanylate cyclase
CBR68_RS14015	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CBR68_RS14050	COG0583	DNA-binding transcription factor activity
CBR68_RS14065	COG2084	Dehydrogenase
CBR68_RS14075	COG1803	Methylglyoxal synthase
CBR68_RS14075	COG1597	lipid kinase activity
CBR68_RS14085	COG0671	phosphoesterase, PA-phosphatase related
CBR68_RS14105	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS14110	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR68_RS14115	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR68_RS14120	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR68_RS14125	COG0649	NAD binding
CBR68_RS14130	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CBR68_RS14140	COG1034	ATP synthesis coupled electron transport
CBR68_RS14145	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBR68_RS14150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR68_RS14160	COG0713	ATP synthesis coupled electron transport
CBR68_RS14175	COG1007	ATP synthesis coupled electron transport
CBR68_RS14185	COG0560	Phosphoserine phosphatase
CBR68_RS14190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBR68_RS14195	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBR68_RS14200	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBR68_RS14205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR68_RS14210	COG0450	alkyl hydroperoxide reductase
CBR68_RS14225	COG1214	PFAM Peptidase M22, glycoprotease
CBR68_RS14230	COG1573	uracil-dna glycosylase
CBR68_RS14235	COG0477	Major facilitator Superfamily
CBR68_RS14240	COG1196	nuclear chromosome segregation
CBR68_RS14250	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBR68_RS14260	COG0765	amino acid transport
CBR68_RS14265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS14275	COG0625	glutathione transferase activity
CBR68_RS14280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR68_RS14285	COG0271	Belongs to the BolA IbaG family
CBR68_RS14290	COG2917	probably involved in intracellular septation
CBR68_RS14295	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR68_RS14300	COG1122	ATPase activity
CBR68_RS14305	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBR68_RS14310	COG1268	BioY protein
CBR68_RS14340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR68_RS14370	COG0411	ABC transporter
CBR68_RS14375	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBR68_RS14380	COG2878	Part of a membrane complex involved in electron transport
CBR68_RS14405	COG0251	oxidation-reduction process
CBR68_RS14415	COG3228	Belongs to the MtfA family
CBR68_RS14420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR68_RS14440	COG0159	tryptophan synthase activity
CBR68_RS14445	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBR68_RS14450	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CBR68_RS14455	COG1530	ribonuclease E activity
CBR68_RS14460	COG0564	pseudouridine synthase activity
CBR68_RS14465	COG0546	phosphoglycolate phosphatase activity
CBR68_RS14470	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CBR68_RS14475	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBR68_RS14480	COG3023	N-Acetylmuramoyl-L-alanine amidase
CBR68_RS14490	COG0424	maF-like protein
CBR68_RS14495	COG1399	metal-binding, possibly nucleic acid-binding protein
CBR68_RS14500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBR68_RS14510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR68_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS14525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBR68_RS14530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBR68_RS14555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR68_RS14560	COG0481	GTPase activity
CBR68_RS14565	COG0681	Belongs to the peptidase S26 family
CBR68_RS14570	COG0571	ribonuclease III activity
CBR68_RS14575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBR68_RS14580	COG1381	Involved in DNA repair and RecF pathway recombination
CBR68_RS14600	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBR68_RS14610	COG0583	DNA-binding transcription factor activity
CBR68_RS14625	COG0583	DNA-binding transcription factor activity
CBR68_RS14635	COG0791	NLP P60 protein
CBR68_RS14640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR68_RS14645	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CBR68_RS14655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR68_RS14660	COG0697	spore germination
CBR68_RS14665	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CBR68_RS14705	COG1446	asparaginase
CBR68_RS14710	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS14715	COG0747	negative chemotaxis
CBR68_RS14720	COG0601	transmembrane transport
CBR68_RS14725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS14745	COG0504	CTP synthase activity
CBR68_RS14755	COG0148	phosphopyruvate hydratase activity
CBR68_RS14770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CBR68_RS14780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR68_RS14785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR68_RS14805	COG1981	membrane
CBR68_RS14825	COG0039	L-malate dehydrogenase activity
CBR68_RS14830	COG2188	Transcriptional regulator
CBR68_RS14835	COG2009	succinate dehydrogenase
CBR68_RS14840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CBR68_RS14845	COG1053	succinate dehydrogenase
CBR68_RS14850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBR68_RS14855	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CBR68_RS14860	COG0372	Belongs to the citrate synthase family
CBR68_RS14865	COG0583	DNA-binding transcription factor activity
CBR68_RS14870	COG3842	ATPase activity
CBR68_RS14880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR68_RS14885	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR68_RS14910	COG3128	pkhd-type hydroxylase
CBR68_RS14915	COG4774	siderophore transport
CBR68_RS14920	COG0280	phosphate acetyltransferase
CBR68_RS14920	COG0281	malic enzyme
CBR68_RS14930	COG1297	OPT oligopeptide transporter protein
CBR68_RS14935	COG0567	Dehydrogenase, E1 component
CBR68_RS14940	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR68_RS14945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR68_RS14950	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CBR68_RS14975	COG2183	response to ionizing radiation
CBR68_RS14980	COG1199	ATP-dependent helicase activity
CBR68_RS15020	COG0564	pseudouridine synthase activity
CBR68_RS15030	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR68_RS15035	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS15040	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CBR68_RS15055	COG0672	)-iron permease
CBR68_RS15070	COG2823	Periplasmic or secreted lipoprotein
CBR68_RS15080	COG3237	CsbD-like
CBR68_RS15085	COG3038	cytochrome b561
CBR68_RS15090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR68_RS15090	COG0189	ligase activity
CBR68_RS15095	COG0189	ligase activity
CBR68_RS15095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR68_RS15100	COG1132	(ABC) transporter
CBR68_RS15110	COG0297	glycogen (starch) synthase activity
CBR68_RS15115	COG2833	Protein of unknown function (DUF455)
CBR68_RS15120	COG2951	lytic endotransglycosylase activity
CBR68_RS15130	COG0589	response to stress
CBR68_RS15140	COG3706	GGDEF domain
CBR68_RS15205	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBR68_RS15220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBR68_RS15225	COG1605	Chorismate mutase
CBR68_RS15225	COG0077	Prephenate dehydratase
CBR68_RS15230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR68_RS15235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR68_RS15240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBR68_RS15245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CBR68_RS15265	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CBR68_RS15270	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CBR68_RS15275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBR68_RS15280	COG0587	DNA-directed DNA polymerase activity
CBR68_RS15290	COG2951	lytic endotransglycosylase activity
CBR68_RS15295	COG0123	including yeast histone deacetylase and acetoin utilization protein
CBR68_RS15310	COG2985	domain, Protein
CBR68_RS15315	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS15320	COG0450	alkyl hydroperoxide reductase
CBR68_RS15325	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBR68_RS15330	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CBR68_RS15335	COG4208	sulfate ABC transporter
CBR68_RS15340	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR68_RS15345	COG0175	sulfate reduction
CBR68_RS15355	COG2895	sulfate adenylyltransferase (ATP) activity
CBR68_RS15375	COG0335	large ribosomal subunit rRNA binding
CBR68_RS15380	COG0494	nUDIX hydrolase
CBR68_RS15385	COG3622	Belongs to the hyi family
CBR68_RS15390	COG1162	GTPase activity
CBR68_RS15395	COG0501	Belongs to the peptidase M48B family
CBR68_RS15400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CBR68_RS15405	COG1335	isochorismatase
CBR68_RS15415	COG0583	DNA-binding transcription factor activity
CBR68_RS15430	COG3396	Phenylacetate-CoA oxygenase
CBR68_RS15435	COG3460	Phenylacetate-CoA oxygenase
CBR68_RS15440	COG3396	Phenylacetate-CoA oxygenase
CBR68_RS15445	COG2151	metal-sulfur cluster biosynthetic enzyme
CBR68_RS15450	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR68_RS15455	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS15460	COG1024	Enoyl-CoA hydratase
CBR68_RS15465	COG2050	protein possibly involved in aromatic compounds catabolism
CBR68_RS15485	COG1126	abc transporter atp-binding protein
CBR68_RS15510	COG2198	Histidine kinase
CBR68_RS15510	COG5002	protein histidine kinase activity
CBR68_RS15510	COG0784	Response regulator, receiver
CBR68_RS15515	COG3437	response regulator, receiver
CBR68_RS15530	COG1802	Transcriptional regulator
CBR68_RS15535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR68_RS15535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR68_RS15545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS15550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CBR68_RS15560	COG3642	lipopolysaccharide core region biosynthetic process
CBR68_RS15565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CBR68_RS15570	COG3842	ATPase activity
CBR68_RS15575	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR68_RS15580	COG1177	transmembrane transport
CBR68_RS15585	COG1393	Belongs to the ArsC family
CBR68_RS15590	COG2094	Belongs to the DNA glycosylase MPG family
CBR68_RS15600	COG1322	Protein conserved in bacteria
CBR68_RS15605	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS15610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBR68_RS15615	COG0704	Plays a role in the regulation of phosphate uptake
CBR68_RS15620	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CBR68_RS15625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR68_RS15625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CBR68_RS15630	COG1643	Atp-dependent helicase
CBR68_RS15645	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS15650	COG0726	polysaccharide deacetylase
CBR68_RS15690	COG1132	(ABC) transporter
CBR68_RS15700	COG1530	ribonuclease E activity
CBR68_RS15730	COG0583	DNA-binding transcription factor activity
CBR68_RS15740	COG0477	Major facilitator Superfamily
CBR68_RS15745	COG0500	methyltransferase
CBR68_RS15750	COG1418	mRNA catabolic process
CBR68_RS15775	COG2204	response regulator
CBR68_RS15780	COG4191	Histidine kinase
CBR68_RS15785	COG1301	dicarboxylic acid transport
CBR68_RS15790	COG0424	maF-like protein
CBR68_RS15795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBR68_RS15800	COG0799	negative regulation of ribosome biogenesis
CBR68_RS15805	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBR68_RS15815	COG0151	Belongs to the GarS family
CBR68_RS15820	COG0217	transcriptional regulatory protein
CBR68_RS15825	COG0433	COG0433 Predicted ATPase
CBR68_RS15830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS15835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR68_RS15840	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS15865	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR68_RS15870	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS15875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS15880	COG0601	transmembrane transport
CBR68_RS15885	COG0747	negative chemotaxis
CBR68_RS15895	COG0473	3-isopropylmalate dehydrogenase activity
CBR68_RS15900	COG2814	Major facilitator Superfamily
CBR68_RS15905	COG1566	PFAM secretion protein HlyD family protein
CBR68_RS15915	COG1846	Transcriptional regulator
CBR68_RS15935	COG0501	Belongs to the peptidase M48B family
CBR68_RS15975	COG1722	exodeoxyribonuclease VII activity
CBR68_RS15980	COG0142	geranyltranstransferase activity
CBR68_RS15985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBR68_RS15990	COG1469	GTP cyclohydrolase I activity
CBR68_RS15995	COG0360	Binds together with S18 to 16S ribosomal RNA
CBR68_RS16000	COG2965	DNA replication, synthesis of RNA primer
CBR68_RS16005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBR68_RS16010	COG0359	binds to the 23S rRNA
CBR68_RS16020	COG0305	Participates in initiation and elongation during chromosome replication
CBR68_RS16030	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CBR68_RS16035	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CBR68_RS16040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBR68_RS16045	COG3737	Protein of unknown function (DUF498/DUF598)
CBR68_RS16050	COG0436	Aminotransferase
CBR68_RS16070	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CBR68_RS16075	COG0308	aminopeptidase N
CBR68_RS16090	COG0312	modulator of DNA gyrase
CBR68_RS16095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR68_RS16100	COG0277	FAD linked oxidase domain protein
CBR68_RS16105	COG0277	FAD linked oxidase domain protein
CBR68_RS16110	COG0277	FAD linked oxidase domain protein
CBR68_RS16115	COG0247	lactate metabolic process
CBR68_RS16140	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS16145	COG0583	DNA-binding transcription factor activity
CBR68_RS16150	COG0482	sulfurtransferase activity
CBR68_RS16155	COG0730	response to heat
CBR68_RS16160	COG0625	glutathione transferase activity
CBR68_RS16170	COG3909	cytochrome
CBR68_RS16200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR68_RS16210	COG3706	GGDEF domain
CBR68_RS16215	COG3706	GGDEF domain
CBR68_RS16240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBR68_RS16245	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CBR68_RS16255	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR68_RS16260	COG0069	glutamate synthase activity
CBR68_RS16265	COG2391	methyltransferase activity
CBR68_RS16270	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CBR68_RS16275	COG0679	Auxin Efflux Carrier
CBR68_RS16305	COG0557	exoribonuclease II activity
CBR68_RS16310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR68_RS16320	COG0776	regulation of translation
CBR68_RS16350	COG0642	Histidine kinase
CBR68_RS16355	COG3158	transport of potassium into the cell
CBR68_RS16370	COG0137	argininosuccinate synthase activity
CBR68_RS16375	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBR68_RS16380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR68_RS16390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR68_RS16405	COG2186	Transcriptional regulator
CBR68_RS16425	COG3836	Belongs to the HpcH HpaI aldolase family
CBR68_RS16430	COG0268	Binds directly to 16S ribosomal RNA
CBR68_RS16455	COG0728	peptidoglycan biosynthetic process
CBR68_RS16465	COG0563	adenylate kinase activity
CBR68_RS16470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBR68_RS16475	COG2835	tetraacyldisaccharide 4'-kinase activity
CBR68_RS16480	COG1663	tetraacyldisaccharide 4'-kinase activity
CBR68_RS16490	COG0811	peptide transport
CBR68_RS16495	COG1570	exodeoxyribonuclease VII activity
CBR68_RS16500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBR68_RS16505	COG0038	chloride channel
CBR68_RS16510	COG0183	Belongs to the thiolase family
CBR68_RS16520	COG1278	Cold shock
CBR68_RS16525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBR68_RS16535	COG4953	penicillin-binding protein 1C
CBR68_RS16540	COG0542	response to heat
CBR68_RS16545	COG2995	paraquat-inducible protein a
CBR68_RS16550	COG3008	intermembrane lipid transfer
CBR68_RS16560	COG0506	proline dehydrogenase activity
CBR68_RS16560	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR68_RS16560	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR68_RS16590	COG2271	Major facilitator Superfamily
CBR68_RS16600	COG0004	ammonium transporteR
CBR68_RS16605	COG0347	Belongs to the P(II) protein family
CBR68_RS16625	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBR68_RS16630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBR68_RS16635	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBR68_RS16640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR68_RS16640	COG0072	phenylalanine-tRNA ligase activity
CBR68_RS16645	COG0776	regulation of translation
CBR68_RS16680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CBR68_RS16705	COG1522	sequence-specific DNA binding
CBR68_RS16755	COG5265	(ABC) transporter
CBR68_RS16760	COG0656	L-ascorbic acid biosynthetic process
CBR68_RS16765	COG0667	Aldo Keto reductase
CBR68_RS16780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR68_RS16805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBR68_RS16825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR68_RS16830	COG3246	L-lysine catabolic process to acetate
CBR68_RS16835	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS16840	COG0583	DNA-binding transcription factor activity
CBR68_RS16850	COG0129	dihydroxy-acid dehydratase activity
CBR68_RS16855	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS16900	COG0154	amidase activity
CBR68_RS16905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS16935	COG2267	carboxylic ester hydrolase activity
CBR68_RS16940	COG0501	Belongs to the peptidase M48B family
CBR68_RS16950	COG0789	Transcriptional regulator
CBR68_RS16955	COG0778	Nitroreductase
CBR68_RS16960	COG0165	Argininosuccinate lyase
CBR68_RS16965	COG0668	transmembrane transport
CBR68_RS16970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CBR68_RS16970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR68_RS16985	COG0583	DNA-binding transcription factor activity
CBR68_RS16995	COG0747	negative chemotaxis
CBR68_RS17000	COG0601	transmembrane transport
CBR68_RS17005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS17010	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS17020	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS17030	COG3161	chorismate lyase activity
CBR68_RS17035	COG1187	pseudouridine synthase activity
CBR68_RS17045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS17070	COG1999	signal sequence binding
CBR68_RS17080	COG0339	signal peptide processing
CBR68_RS17085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBR68_RS17090	COG4566	intracellular signal transduction
CBR68_RS17100	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CBR68_RS17105	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR68_RS17110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR68_RS17150	COG0745	RESPONSE REGULATOR receiver
CBR68_RS17165	COG0840	transmembrane signaling receptor activity
CBR68_RS17170	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CBR68_RS17175	COG2201	protein-glutamate methylesterase activity
CBR68_RS17180	COG0745	RESPONSE REGULATOR receiver
CBR68_RS17185	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CBR68_RS17190	COG0840	transmembrane signaling receptor activity
CBR68_RS17215	COG2747	anti-sigma28 factor FlgM
CBR68_RS17240	COG1749	Flagellar hook protein flgE
CBR68_RS17260	COG1706	bacterial-type flagellum-dependent cell motility
CBR68_RS17270	COG1256	bacterial-type flagellum assembly
CBR68_RS17280	COG0840	transmembrane signaling receptor activity
CBR68_RS17285	COG0840	transmembrane signaling receptor activity
CBR68_RS17295	COG0840	transmembrane signaling receptor activity
CBR68_RS17300	COG0840	transmembrane signaling receptor activity
CBR68_RS17325	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR68_RS17335	COG1580	Controls the rotational direction of flagella during chemotaxis
CBR68_RS17345	COG2882	bacterial-type flagellum organization
CBR68_RS17355	COG1317	bacterial-type flagellum organization
CBR68_RS17360	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR68_RS17365	COG1766	The M ring may be actively involved in energy transduction
CBR68_RS17370	COG1677	Flagellar hook-basal body complex protein FliE
CBR68_RS17380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBR68_RS17400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CBR68_RS17420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS17425	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS17435	COG0285	dihydrofolate synthase activity
CBR68_RS17445	COG1286	toxin biosynthetic process
CBR68_RS17465	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CBR68_RS17470	COG0024	Methionine aminopeptidase
CBR68_RS17475	COG0052	Belongs to the universal ribosomal protein uS2 family
CBR68_RS17480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBR68_RS17485	COG0528	UMP kinase activity
CBR68_RS17490	COG0233	cytoplasmic translational termination
CBR68_RS17495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBR68_RS17500	COG0575	Belongs to the CDS family
CBR68_RS17505	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBR68_RS17510	COG0750	zinc metalloprotease
CBR68_RS17515	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR68_RS17525	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR68_RS17530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBR68_RS17540	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR68_RS17545	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBR68_RS17550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR68_RS17560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBR68_RS17585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBR68_RS17595	COG2914	Belongs to the UPF0125 (RnfH) family
CBR68_RS17600	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS17605	COG1024	Enoyl-CoA hydratase
CBR68_RS17605	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS17625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBR68_RS17630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBR68_RS17640	COG0084	hydrolase, TatD family'
CBR68_RS17655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS17660	COG0765	amino acid transport
CBR68_RS17665	COG1126	abc transporter atp-binding protein
CBR68_RS17670	COG0010	Belongs to the arginase family
CBR68_RS17690	COG4221	oxidoreductase activity
CBR68_RS17695	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR68_RS17705	COG2059	Chromate
CBR68_RS17710	COG0640	Transcriptional regulator
CBR68_RS17720	COG0740	serine-type endopeptidase activity
CBR68_RS17730	COG0095	Lipoate-protein ligase
CBR68_RS17755	COG0386	Belongs to the glutathione peroxidase family
CBR68_RS17780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS17825	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR68_RS17830	COG2259	Doxx family
CBR68_RS17850	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS17860	COG0842	Transport permease protein
CBR68_RS17865	COG1129	ABC transporter
CBR68_RS17865	COG0842	Transport permease protein
CBR68_RS17870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR68_RS17880	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR68_RS17900	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CBR68_RS17925	COG2733	membrane
CBR68_RS17935	COG3042	response to heat
CBR68_RS17940	COG3258	Cytochrome c
CBR68_RS17970	COG3958	Transketolase
CBR68_RS17975	COG3959	Transketolase, thiamine diphosphate binding domain
CBR68_RS17985	COG1802	Transcriptional regulator
CBR68_RS18035	COG0583	DNA-binding transcription factor activity
CBR68_RS18040	COG0028	Belongs to the TPP enzyme family
CBR68_RS18045	COG0477	Major facilitator Superfamily
CBR68_RS18050	COG0583	DNA-binding transcription factor activity
CBR68_RS18055	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS18060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS18070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR68_RS18090	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR68_RS18090	COG0519	Catalyzes the synthesis of GMP from XMP
CBR68_RS18105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS18120	COG1024	Enoyl-CoA hydratase
CBR68_RS18135	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS18140	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS18185	COG1122	ATPase activity
CBR68_RS18200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR68_RS18205	COG2900	Belongs to the SlyX family
CBR68_RS18220	COG0456	acetyltransferase
CBR68_RS18225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR68_RS18260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR68_RS18275	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBR68_RS18280	COG0714	Associated with various cellular activities
CBR68_RS18300	COG2304	oxidoreductase activity
CBR68_RS18315	COG3119	arylsulfatase activity
CBR68_RS18330	COG3706	GGDEF domain
CBR68_RS18345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS18375	COG0583	DNA-binding transcription factor activity
CBR68_RS18390	COG1335	isochorismatase
CBR68_RS18405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS18455	COG0066	3-isopropylmalate dehydratase activity
CBR68_RS18460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBR68_RS18465	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS18470	COG4948	Mandelate Racemase Muconate Lactonizing
CBR68_RS18475	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR68_RS18480	COG3842	ATPase activity
CBR68_RS18485	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR68_RS18495	COG3833	ABC-type maltose transport systems, permease component
CBR68_RS18500	COG1175	transmembrane transport
CBR68_RS18505	COG2182	Extracellular solute-binding protein
CBR68_RS18515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS18520	COG0765	amino acid transport
CBR68_RS18525	COG0765	amino acid transport
CBR68_RS18540	COG3665	Urea carboxylase-associated protein
CBR68_RS18560	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR68_RS18585	COG0583	DNA-binding transcription factor activity
CBR68_RS18600	COG1126	abc transporter atp-binding protein
CBR68_RS18620	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS18630	COG1937	Protein conserved in bacteria
CBR68_RS18650	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS18675	COG2863	cytochrome
CBR68_RS18680	COG3568	Endonuclease Exonuclease Phosphatase
CBR68_RS18685	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR68_RS18690	COG0392	lysyltransferase activity
CBR68_RS18695	COG0166	Belongs to the GPI family
CBR68_RS18710	COG1546	Belongs to the CinA family
CBR68_RS18710	COG1058	Belongs to the CinA family
CBR68_RS18720	COG0668	transmembrane transport
CBR68_RS18725	COG0297	glycogen (starch) synthase activity
CBR68_RS18735	COG0366	Alpha amylase catalytic
CBR68_RS18740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR68_RS18750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR68_RS18755	COG1640	4-alpha-glucanotransferase
CBR68_RS18785	COG3685	Protein conserved in bacteria
CBR68_RS18790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBR68_RS18795	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS18805	COG1216	Glycosyl transferase, family 2
CBR68_RS18840	COG2192	nodulation
CBR68_RS18850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR68_RS18855	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS18860	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS18875	COG5265	(ABC) transporter
CBR68_RS18895	COG0028	Belongs to the TPP enzyme family
CBR68_RS18900	COG2204	response regulator
CBR68_RS18905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR68_RS18910	COG0583	DNA-binding transcription factor activity
CBR68_RS18915	COG0477	Major facilitator Superfamily
CBR68_RS18920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR68_RS18940	COG1137	ATPase activity
CBR68_RS18965	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS18970	COG1129	ABC transporter
CBR68_RS18985	COG2267	carboxylic ester hydrolase activity
CBR68_RS19010	COG0402	S-adenosylhomocysteine deaminase activity
CBR68_RS19015	COG0747	negative chemotaxis
CBR68_RS19020	COG0601	transmembrane transport
CBR68_RS19025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR68_RS19030	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS19035	COG1063	alcohol dehydrogenase
CBR68_RS19060	COG2175	clavaminate synthase activity
CBR68_RS19065	COG1454	alcohol dehydrogenase
CBR68_RS19070	COG0583	DNA-binding transcription factor activity
CBR68_RS19080	COG1024	Enoyl-CoA hydratase
CBR68_RS19090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS19100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR68_RS19110	COG1024	Enoyl-CoA hydratase
CBR68_RS19110	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR68_RS19115	COG0183	Belongs to the thiolase family
CBR68_RS19120	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS19125	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS19130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR68_RS19145	COG0154	amidase activity
CBR68_RS19150	COG2271	Major facilitator Superfamily
CBR68_RS19160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR68_RS19190	COG0318	PFAM AMP-dependent synthetase and ligase
CBR68_RS19200	COG2267	carboxylic ester hydrolase activity
CBR68_RS19210	COG1024	Enoyl-CoA hydratase
CBR68_RS19220	COG0431	NADPH-dependent FMN reductase
CBR68_RS19235	COG0683	leucine binding
CBR68_RS19260	COG2819	hydrolase of the alpha beta superfamily
CBR68_RS19275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR68_RS19285	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR68_RS19315	COG1126	abc transporter atp-binding protein
CBR68_RS19320	COG0765	amino acid transport
CBR68_RS19325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS19350	COG0410	ABC transporter
CBR68_RS19370	COG2200	EAL domain
CBR68_RS19380	COG1595	DNA-templated transcription, initiation
CBR68_RS19395	COG1253	flavin adenine dinucleotide binding
CBR68_RS19405	COG5001	Diguanylate cyclase
CBR68_RS19405	COG4251	negative regulation of phosphorylation
CBR68_RS19405	COG3706	GGDEF domain
CBR68_RS19405	COG2203	Gaf domain
CBR68_RS19410	COG2197	response regulator
CBR68_RS19415	COG2205	protein histidine kinase activity
CBR68_RS19415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS19420	COG2814	Major facilitator Superfamily
CBR68_RS19425	COG0076	glutamate decarboxylase activity
CBR68_RS19430	COG2985	domain, Protein
CBR68_RS19435	COG3189	MarR family transcriptional regulator
CBR68_RS19440	COG2186	Transcriptional regulator
CBR68_RS19445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS19455	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR68_RS19455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR68_RS19465	COG0028	Belongs to the TPP enzyme family
CBR68_RS19475	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS19485	COG0688	phosphatidylethanolamine metabolic process
CBR68_RS19495	COG1464	Belongs to the NlpA lipoprotein family
CBR68_RS19515	COG2363	Small membrane protein
CBR68_RS19520	COG0697	spore germination
CBR68_RS19525	COG0625	glutathione transferase activity
CBR68_RS19530	COG2133	pyrroloquinoline quinone binding
CBR68_RS19535	COG0625	glutathione transferase activity
CBR68_RS19545	COG1794	racemase activity, acting on amino acids and derivatives
CBR68_RS19565	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR68_RS19575	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CBR68_RS19590	COG1175	transmembrane transport
CBR68_RS19595	COG0395	ABC-type sugar transport system, permease component
CBR68_RS19600	COG3842	ATPase activity
CBR68_RS19615	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR68_RS19630	COG0438	transferase activity, transferring glycosyl groups
CBR68_RS19650	COG1216	Glycosyl transferase, family 2
CBR68_RS19665	COG0783	Belongs to the Dps family
CBR68_RS19675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CBR68_RS19690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR68_RS19735	COG0583	DNA-binding transcription factor activity
CBR68_RS19740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBR68_RS19760	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR68_RS19770	COG3842	ATPase activity
CBR68_RS19775	COG1741	Belongs to the pirin family
CBR68_RS19780	COG1741	Belongs to the pirin family
CBR68_RS19785	COG0583	DNA-binding transcription factor activity
CBR68_RS19800	COG5002	protein histidine kinase activity
CBR68_RS19800	COG0784	Response regulator, receiver
CBR68_RS19800	COG2205	protein histidine kinase activity
CBR68_RS19815	COG3852	Histidine kinase
CBR68_RS19820	COG0174	glutamine synthetase
CBR68_RS19825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR68_RS19830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBR68_RS19835	COG5001	Diguanylate cyclase
CBR68_RS19835	COG3300	MHYT domain
CBR68_RS19840	COG0840	transmembrane signaling receptor activity
CBR68_RS19850	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS19855	COG2079	MmgE PrpD family protein
CBR68_RS19865	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CBR68_RS19870	COG1561	YicC-like family, N-terminal region
CBR68_RS19885	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR68_RS19890	COG0791	NLP P60 protein
CBR68_RS19895	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS19900	COG0194	GDP metabolic process
CBR68_RS19905	COG1758	RNA polymerase activity
CBR68_RS19910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR68_RS19915	COG1126	abc transporter atp-binding protein
CBR68_RS19920	COG0765	amino acid transport
CBR68_RS19925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS19950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS19965	COG2831	hemolysin activation secretion protein
CBR68_RS19975	COG3188	usher protein
CBR68_RS19980	COG3121	Chaperone
CBR68_RS19990	COG3064	Membrane
CBR68_RS19990	COG3210	domain, Protein
CBR68_RS19990	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR68_RS19990	COG3210	domain, Protein
CBR68_RS19990	COG3064	Membrane
CBR68_RS19990	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR68_RS20000	COG4181	ATPase activity
CBR68_RS20010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR68_RS20015	COG0584	glycerophosphoryl diester phosphodiesterase
CBR68_RS20020	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CBR68_RS20030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR68_RS20030	COG0678	peroxiredoxin activity
CBR68_RS20045	COG0789	Transcriptional regulator
CBR68_RS20050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBR68_RS20075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR68_RS20085	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBR68_RS20105	COG3618	amidohydrolase
CBR68_RS20110	COG0583	DNA-binding transcription factor activity
CBR68_RS20115	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBR68_RS20120	COG2252	PERMEase
CBR68_RS20125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR68_RS20130	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR68_RS20160	COG0583	DNA-binding transcription factor activity
CBR68_RS20165	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBR68_RS20170	COG0488	(ABC) transporter
CBR68_RS20175	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR68_RS20180	COG0590	tRNA wobble adenosine to inosine editing
CBR68_RS20195	COG1320	monovalent cation:proton antiporter activity
CBR68_RS20200	COG2212	antiporter activity
CBR68_RS20210	COG0651	ATP synthesis coupled electron transport
CBR68_RS20215	COG1006	Multisubunit Na H antiporter MnhC subunit
CBR68_RS20220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CBR68_RS20220	COG2111	Na H antiporter
CBR68_RS20225	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS20235	COG0420	3'-5' exonuclease activity
CBR68_RS20240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR68_RS20245	COG1522	sequence-specific DNA binding
CBR68_RS20285	COG2130	NADP-dependent
CBR68_RS20300	COG1131	(ABC) transporter
CBR68_RS20305	COG0842	Transport permease protein
CBR68_RS20315	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBR68_RS20350	COG0235	Class ii aldolase
CBR68_RS20355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR68_RS20360	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS20370	COG1414	Transcriptional regulator
CBR68_RS20375	COG0602	queuosine metabolic process
CBR68_RS20380	COG0720	synthase
CBR68_RS20390	COG1289	transmembrane transporter activity
CBR68_RS20400	COG1566	PFAM secretion protein HlyD family protein
CBR68_RS20410	COG0400	carboxylic ester hydrolase activity
CBR68_RS20415	COG0840	transmembrane signaling receptor activity
CBR68_RS20430	COG0587	DNA-directed DNA polymerase activity
CBR68_RS20440	COG0390	transport system, permease component
CBR68_RS20445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR68_RS20450	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CBR68_RS20490	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBR68_RS20500	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS20505	COG1280	lysine exporter protein (LysE YggA)
CBR68_RS20510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR68_RS20530	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CBR68_RS20555	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS20580	COG0583	DNA-binding transcription factor activity
CBR68_RS20595	COG1522	sequence-specific DNA binding
CBR68_RS20605	COG2814	Major facilitator Superfamily
CBR68_RS20620	COG1396	sequence-specific DNA binding
CBR68_RS20640	COG0183	Belongs to the thiolase family
CBR68_RS20650	COG0583	DNA-binding transcription factor activity
CBR68_RS20655	COG2814	Major facilitator Superfamily
CBR68_RS20660	COG0656	L-ascorbic acid biosynthetic process
CBR68_RS20670	COG2807	transmembrane transport
CBR68_RS20675	COG2207	Transcriptional regulator
CBR68_RS20690	COG1960	acyl-CoA dehydrogenase activity
CBR68_RS20695	COG1024	Enoyl-CoA hydratase
CBR68_RS20710	COG1309	transcriptional regulator
CBR68_RS20725	COG0653	protein targeting
CBR68_RS20760	COG4585	Histidine kinase
CBR68_RS20770	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBR68_RS20775	COG1595	DNA-templated transcription, initiation
CBR68_RS20780	COG3712	iron ion homeostasis
CBR68_RS20785	COG4774	siderophore transport
CBR68_RS20790	COG2814	Major facilitator Superfamily
CBR68_RS20795	COG0583	DNA-binding transcription factor activity
CBR68_RS20800	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS20810	COG1349	DNA-binding transcription factor activity
CBR68_RS20820	COG1012	belongs to the aldehyde dehydrogenase family
CBR68_RS20830	COG0411	ABC transporter
CBR68_RS20870	COG0384	phenazine biosynthesis protein PhzF
CBR68_RS20875	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS20895	COG0667	Aldo Keto reductase
CBR68_RS20905	COG0667	Aldo Keto reductase
CBR68_RS20925	COG0667	Aldo Keto reductase
CBR68_RS20935	COG0519	Catalyzes the synthesis of GMP from XMP
CBR68_RS20935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR68_RS20950	COG1695	Transcriptional regulator
CBR68_RS20965	COG2072	flavoprotein involved in K transport
CBR68_RS20970	COG0601	transmembrane transport
CBR68_RS20980	COG0444	Belongs to the ABC transporter superfamily
CBR68_RS20985	COG4608	Belongs to the ABC transporter superfamily
CBR68_RS20990	COG0747	negative chemotaxis
CBR68_RS21030	COG0047	phosphoribosylformylglycinamidine synthase activity
CBR68_RS21030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBR68_RS21040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR68_RS21045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR68_RS21045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR68_RS21050	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR68_RS21060	COG0613	PHP domain protein
CBR68_RS21085	COG2501	S4 domain
CBR68_RS21090	COG0084	hydrolase, TatD family'
CBR68_RS21095	COG1136	(ABC) transporter
CBR68_RS21110	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBR68_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS21125	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBR68_RS21135	COG1309	transcriptional regulator
CBR68_RS21140	COG1022	Amp-dependent synthetase and ligase
CBR68_RS21170	COG1024	Enoyl-CoA hydratase
CBR68_RS21175	COG1803	Methylglyoxal synthase
CBR68_RS21185	COG2975	iron-sulfur cluster assembly
CBR68_RS21190	COG0633	Ferredoxin
CBR68_RS21195	COG0443	Heat shock 70 kDa protein
CBR68_RS21200	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBR68_RS21205	COG0316	Belongs to the HesB IscA family
CBR68_RS21210	COG0822	iron-sulfur transferase activity
CBR68_RS21215	COG1104	cysteine desulfurase activity
CBR68_RS21225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CBR68_RS21230	COG0556	nucleotide-excision repair
CBR68_RS21240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBR68_RS21245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR68_RS21250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBR68_RS21255	COG0740	serine-type endopeptidase activity
CBR68_RS21260	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBR68_RS21270	COG1278	Cold shock
CBR68_RS21280	COG1278	Cold shock
CBR68_RS21305	COG3468	outer membrane autotransporter barrel domain protein
CBR68_RS21330	COG2171	N-acyltransferase activity
CBR68_RS21335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR68_RS21340	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR68_RS21345	COG0488	(ABC) transporter
CBR68_RS21350	COG0210	DNA helicase
CBR68_RS21365	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR68_RS21365	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR68_RS21370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBR68_RS21375	COG0196	riboflavin kinase activity
CBR68_RS21380	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBR68_RS21385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBR68_RS21390	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBR68_RS21400	COG1522	sequence-specific DNA binding
CBR68_RS21415	COG0586	Pfam SNARE associated Golgi protein
CBR68_RS21425	COG0756	dUTP diphosphatase activity
CBR68_RS21430	COG1902	pentaerythritol trinitrate reductase activity
CBR68_RS21435	COG1126	abc transporter atp-binding protein
CBR68_RS21440	COG0765	amino acid transport
CBR68_RS21445	COG0765	amino acid transport
CBR68_RS21450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR68_RS21460	COG2423	ornithine cyclodeaminase activity
CBR68_RS21465	COG1764	response to oxidative stress
CBR68_RS21470	COG1914	H( )-stimulated, divalent metal cation uptake system
CBR68_RS21475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBR68_RS21480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBR68_RS21495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBR68_RS21500	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBR68_RS21505	COG2197	response regulator
CBR68_RS21510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR68_RS21530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS21535	COG0840	transmembrane signaling receptor activity
CBR68_RS21555	COG0135	phosphoribosylanthranilate isomerase activity
CBR68_RS21560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR68_RS21565	COG0101	tRNA pseudouridine synthase activity
CBR68_RS21575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBR68_RS21580	COG0473	3-isopropylmalate dehydrogenase activity
CBR68_RS21585	COG0066	3-isopropylmalate dehydratase activity
CBR68_RS21595	COG2197	response regulator
CBR68_RS21610	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBR68_RS21620	COG2205	protein histidine kinase activity
CBR68_RS21630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBR68_RS21640	COG1295	ribonuclease BN
CBR68_RS21650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBR68_RS21680	COG1450	Type ii and iii secretion system protein
CBR68_RS21715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR68_RS21755	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS21770	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS21800	COG0181	hydroxymethylbilane synthase activity
CBR68_RS21805	COG0861	Integral membrane protein TerC family
CBR68_RS21810	COG0861	Integral membrane protein TerC family
CBR68_RS21815	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CBR68_RS21820	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR68_RS21830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR68_RS21840	COG2137	regulation of response to DNA damage stimulus
CBR68_RS21845	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBR68_RS21870	COG2974	May be involved in recombination
CBR68_RS21875	COG0540	Belongs to the ATCase OTCase family
CBR68_RS21905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR68_RS21935	COG0500	methyltransferase
CBR68_RS21940	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS21955	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR68_RS21960	COG0747	negative chemotaxis
CBR68_RS21980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR68_RS22005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR68_RS22035	COG0811	peptide transport
CBR68_RS22070	COG2188	Transcriptional regulator
CBR68_RS22075	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS22090	COG0583	DNA-binding transcription factor activity
CBR68_RS22100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR68_RS22110	COG4172	Belongs to the ABC transporter superfamily
CBR68_RS22120	COG0601	transmembrane transport
CBR68_RS22125	COG4166	transmembrane transport
CBR68_RS22130	COG2267	carboxylic ester hydrolase activity
CBR68_RS22135	COG4638	Rieske (2fe-2S)
CBR68_RS22145	COG0583	DNA-binding transcription factor activity
CBR68_RS22150	COG2146	nitrite reductase [NAD(P)H] activity
CBR68_RS22155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR68_RS22160	COG1595	DNA-templated transcription, initiation
CBR68_RS22165	COG3712	iron ion homeostasis
CBR68_RS22170	COG4774	siderophore transport
CBR68_RS22195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR68_RS22205	COG3246	L-lysine catabolic process to acetate
CBR68_RS22210	COG3181	Tripartite tricarboxylate transporter family receptor
CBR68_RS22225	COG1028	Short-chain dehydrogenase reductase Sdr
CBR68_RS22230	COG0583	DNA-binding transcription factor activity
CBR68_RS22260	COG0457	Tetratricopeptide repeat
CBR68_RS22265	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CBR68_RS22270	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS22275	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS22280	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS22285	COG0003	Pfam Anion-transporting ATPase
CBR68_RS22305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR68_RS22345	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBR68_RS22360	COG1215	transferase activity, transferring glycosyl groups
CBR68_RS22370	COG3307	-O-antigen