locus-tag	class	description
CBR69_RS00025	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS00035	COG2030	dehydratase
CBR69_RS00050	COG1024	Enoyl-CoA hydratase
CBR69_RS00100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS00120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS00130	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS00135	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS00140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS00150	COG0583	DNA-binding transcription factor activity
CBR69_RS00155	COG0372	Belongs to the citrate synthase family
CBR69_RS00200	COG0701	Predicted permease
CBR69_RS00245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR69_RS00280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBR69_RS00290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR69_RS00295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CBR69_RS00305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBR69_RS00310	COG3620	sequence-specific DNA binding
CBR69_RS00315	COG2233	PERMEase
CBR69_RS00345	COG0406	alpha-ribazole phosphatase activity
CBR69_RS00350	COG4221	oxidoreductase activity
CBR69_RS00360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBR69_RS00365	COG0505	Belongs to the CarA family
CBR69_RS00370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBR69_RS00375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR69_RS00385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR69_RS00390	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS00395	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBR69_RS00400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBR69_RS00405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CBR69_RS00420	COG1074	ATP-dependent DNA helicase activity
CBR69_RS00440	COG1686	Belongs to the peptidase S11 family
CBR69_RS00450	COG0693	protein deglycase activity
CBR69_RS00460	COG4974	Belongs to the 'phage' integrase family
CBR69_RS00465	COG0583	DNA-binding transcription factor activity
CBR69_RS00470	COG0028	Belongs to the TPP enzyme family
CBR69_RS00475	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS00485	COG0028	Belongs to the TPP enzyme family
CBR69_RS00490	COG1126	abc transporter atp-binding protein
CBR69_RS00495	COG0765	amino acid transport
CBR69_RS00500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS00515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS00520	COG0009	L-threonylcarbamoyladenylate synthase
CBR69_RS00525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBR69_RS00530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CBR69_RS00540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBR69_RS00550	COG1301	dicarboxylic acid transport
CBR69_RS00555	COG0456	acetyltransferase
CBR69_RS00585	COG3454	Phosphonate metabolism
CBR69_RS00590	COG4778	phosphonate C-P lyase system protein PhnL
CBR69_RS00595	COG4107	phosphonate C-P lyase system protein PhnK
CBR69_RS00600	COG3627	carbon phosphorus lyase activity
CBR69_RS00605	COG3626	phosphonate metabolism
CBR69_RS00615	COG3624	Phosphonate C-P lyase system protein PhnG
CBR69_RS00620	COG2188	Transcriptional regulator
CBR69_RS00625	COG3454	Phosphonate metabolism
CBR69_RS00635	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CBR69_RS00640	COG3639	organic phosphonate transmembrane transporter activity
CBR69_RS00645	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CBR69_RS00650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR69_RS00655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR69_RS00665	COG0739	heme binding
CBR69_RS00675	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR69_RS00680	COG0306	phosphate transporter
CBR69_RS00725	COG0625	glutathione transferase activity
CBR69_RS00745	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBR69_RS00750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CBR69_RS00760	COG0126	phosphoglycerate kinase activity
CBR69_RS00765	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBR69_RS00770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBR69_RS00775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CBR69_RS00790	COG0281	malic enzyme
CBR69_RS00790	COG0280	phosphate acetyltransferase
CBR69_RS00800	COG0436	Aminotransferase
CBR69_RS00805	COG0741	lytic transglycosylase activity
CBR69_RS00810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CBR69_RS00825	COG4575	ribosome binding
CBR69_RS00835	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CBR69_RS00835	COG1648	precorrin-2 dehydrogenase activity
CBR69_RS00840	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBR69_RS00845	COG2027	D-alanyl-D-alanine carboxypeptidase
CBR69_RS00850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBR69_RS00855	COG0343	queuine tRNA-ribosyltransferase activity
CBR69_RS00860	COG1862	Preprotein translocase
CBR69_RS00865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR69_RS00870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR69_RS00900	COG0667	Aldo Keto reductase
CBR69_RS00905	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBR69_RS00910	COG4535	Mg2 and Co2 transporter CorC
CBR69_RS00915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBR69_RS00920	COG1702	phosphate starvation-inducible protein PhoH
CBR69_RS00925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR69_RS00975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CBR69_RS00980	COG0697	spore germination
CBR69_RS00990	COG0494	nUDIX hydrolase
CBR69_RS01000	COG0583	DNA-binding transcription factor activity
CBR69_RS01005	COG3530	Putative quorum-sensing-regulated virulence factor
CBR69_RS01015	COG2814	Major facilitator Superfamily
CBR69_RS01035	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS01040	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS01045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS01055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR69_RS01060	COG0583	DNA-binding transcription factor activity
CBR69_RS01100	COG2814	Major facilitator Superfamily
CBR69_RS01110	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
CBR69_RS01120	COG0628	permease
CBR69_RS01125	COG0842	Transport permease protein
CBR69_RS01130	COG1131	(ABC) transporter
CBR69_RS01135	COG1764	response to oxidative stress
CBR69_RS01140	COG1846	Transcriptional regulator
CBR69_RS01155	COG0348	domain, Protein
CBR69_RS01175	COG3278	Belongs to the heme-copper respiratory oxidase family
CBR69_RS01185	COG2217	Heavy metal translocating P-type atpase
CBR69_RS01190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS01195	COG0156	8-amino-7-oxononanoate synthase activity
CBR69_RS01205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBR69_RS01205	COG4106	trans-aconitate 2-methyltransferase activity
CBR69_RS01210	COG2224	Isocitrate lyase
CBR69_RS01215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR69_RS01215	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBR69_RS01225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CBR69_RS01235	COG1472	Belongs to the glycosyl hydrolase 3 family
CBR69_RS01240	COG0736	holo-[acyl-carrier-protein] synthase activity
CBR69_RS01245	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CBR69_RS01255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR69_RS01260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS01265	COG0745	RESPONSE REGULATOR receiver
CBR69_RS01285	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR69_RS01290	COG4149	molybdate abc transporter
CBR69_RS01295	COG0725	ABC transporter, periplasmic molybdate-binding protein
CBR69_RS01305	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS01315	COG0667	Aldo Keto reductase
CBR69_RS01320	COG2032	superoxide dismutase activity
CBR69_RS01330	COG0318	PFAM AMP-dependent synthetase and ligase
CBR69_RS01335	COG1024	Enoyl-CoA hydratase
CBR69_RS01345	COG1802	Transcriptional regulator
CBR69_RS01365	COG1217	gtp-binding protein TYPA
CBR69_RS01370	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBR69_RS01375	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBR69_RS01380	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBR69_RS01385	COG0195	Participates in both transcription termination and antitermination
CBR69_RS01385	COG2251	uridine kinase activity
CBR69_RS01390	COG0779	Required for maturation of 30S ribosomal subunits
CBR69_RS01395	COG1187	pseudouridine synthase activity
CBR69_RS01400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBR69_RS01410	COG0583	DNA-binding transcription factor activity
CBR69_RS01415	COG0523	cobalamin synthesis protein
CBR69_RS01445	COG0625	glutathione transferase activity
CBR69_RS01450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBR69_RS01460	COG2003	Belongs to the UPF0758 family
CBR69_RS01465	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CBR69_RS01470	COG3483	tryptophan 2,3-dioxygenase activity
CBR69_RS01475	COG0254	rRNA binding
CBR69_RS01510	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS01515	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBR69_RS01525	COG1562	ergosterol biosynthetic process
CBR69_RS01530	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR69_RS01530	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CBR69_RS01535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBR69_RS01560	COG1477	protein flavinylation
CBR69_RS01565	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CBR69_RS01575	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR69_RS01585	COG0542	response to heat
CBR69_RS01595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBR69_RS01610	COG0678	peroxiredoxin activity
CBR69_RS01620	COG0412	Dienelactone hydrolase
CBR69_RS01630	COG0315	cyclic pyranopterin monophosphate synthase activity
CBR69_RS01640	COG0314	molybdopterin synthase activity
CBR69_RS01645	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBR69_RS01650	COG0303	'Molybdopterin
CBR69_RS01655	COG0746	molybdenum cofactor guanylyltransferase activity
CBR69_RS01660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBR69_RS01680	COG3383	formate dehydrogenase (NAD+) activity
CBR69_RS01695	COG2264	protein methyltransferase activity
CBR69_RS01715	COG5006	permease, DMT superfamily
CBR69_RS01720	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS01770	COG1129	ABC transporter
CBR69_RS01780	COG1666	GTP binding
CBR69_RS01810	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR69_RS01815	COG1845	cytochrome c oxidase, subunit III
CBR69_RS01820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR69_RS01830	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CBR69_RS01855	COG0783	Belongs to the Dps family
CBR69_RS01870	COG1346	cytolysis
CBR69_RS01875	COG1380	Effector of murein hydrolase LrgA
CBR69_RS01880	COG0583	DNA-binding transcription factor activity
CBR69_RS01890	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS01895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS01900	COG0601	transmembrane transport
CBR69_RS01905	COG0747	negative chemotaxis
CBR69_RS01915	COG0598	Magnesium transport protein CorA
CBR69_RS01920	COG0210	DNA helicase
CBR69_RS01935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR69_RS01940	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS01950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR69_RS01960	COG1045	serine acetyltransferase
CBR69_RS01965	COG1309	transcriptional regulator
CBR69_RS01970	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS01980	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS01980	COG1024	Enoyl-CoA hydratase
CBR69_RS01985	COG2067	long-chain fatty acid transport protein
CBR69_RS01990	COG1024	Enoyl-CoA hydratase
CBR69_RS01990	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS01995	COG0183	Belongs to the thiolase family
CBR69_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
CBR69_RS02020	COG1902	pentaerythritol trinitrate reductase activity
CBR69_RS02045	COG0251	oxidation-reduction process
CBR69_RS02055	COG1832	CoA-binding protein
CBR69_RS02060	COG1414	Transcriptional regulator
CBR69_RS02075	COG0583	DNA-binding transcription factor activity
CBR69_RS02100	COG0583	DNA-binding transcription factor activity
CBR69_RS02115	COG4993	Dehydrogenase
CBR69_RS02125	COG4772	TonB-dependent receptor
CBR69_RS02130	COG2814	Major facilitator Superfamily
CBR69_RS02145	COG1132	(ABC) transporter
CBR69_RS02160	COG0037	tRNA processing
CBR69_RS02165	COG0825	malonyl-CoA metabolic process
CBR69_RS02175	COG0215	cysteine-tRNA ligase activity
CBR69_RS02185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBR69_RS02190	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR69_RS02195	COG1968	undecaprenyl-diphosphatase activity
CBR69_RS02200	COG1253	flavin adenine dinucleotide binding
CBR69_RS02205	COG0483	inositol monophosphate 1-phosphatase activity
CBR69_RS02210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CBR69_RS02225	COG0668	transmembrane transport
CBR69_RS02250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBR69_RS02260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR69_RS02295	COG3360	Dodecin
CBR69_RS02315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CBR69_RS02320	COG2850	peptidyl-arginine hydroxylation
CBR69_RS02330	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CBR69_RS02335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR69_RS02340	COG1994	Peptidase M50
CBR69_RS02345	COG0009	L-threonylcarbamoyladenylate synthase
CBR69_RS02350	COG2321	neutral zinc metallopeptidase
CBR69_RS02375	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR69_RS02380	COG0583	DNA-binding transcription factor activity
CBR69_RS02410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR69_RS02420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR69_RS02430	COG2072	flavoprotein involved in K transport
CBR69_RS02435	COG3842	ATPase activity
CBR69_RS02440	COG3321	synthase
CBR69_RS02440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR69_RS02440	COG0604	alcohol dehydrogenase
CBR69_RS02440	COG4221	oxidoreductase activity
CBR69_RS02450	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR69_RS02455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR69_RS02460	COG1177	transmembrane transport
CBR69_RS02465	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR69_RS02475	COG1126	abc transporter atp-binding protein
CBR69_RS02480	COG0765	amino acid transport
CBR69_RS02490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS02500	COG0251	oxidation-reduction process
CBR69_RS02515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR69_RS02530	COG2020	methyltransferase activity
CBR69_RS02555	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR69_RS02560	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBR69_RS02560	COG3608	succinylglutamate desuccinylase aspartoacylase
CBR69_RS02570	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS02600	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS02640	COG2199	diguanylate cyclase activity
CBR69_RS02640	COG2200	EAL domain
CBR69_RS02640	COG2202	Pas domain
CBR69_RS02645	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CBR69_RS02650	COG1414	Transcriptional regulator
CBR69_RS02670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS02690	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS02700	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS02705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS02710	COG2186	Transcriptional regulator
CBR69_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS02735	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR69_RS02755	COG4604	ABC transporter, ATP-binding protein
CBR69_RS02760	COG4605	iron ion homeostasis
CBR69_RS02765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR69_RS02770	COG4607	ABC-type enterochelin transport system periplasmic component
CBR69_RS02775	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS02780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR69_RS02785	COG0149	triose-phosphate isomerase activity
CBR69_RS02790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR69_RS02790	COG4221	oxidoreductase activity
CBR69_RS02790	COG3321	synthase
CBR69_RS02790	COG0604	alcohol dehydrogenase
CBR69_RS02815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR69_RS02820	COG0583	DNA-binding transcription factor activity
CBR69_RS02850	COG1185	polyribonucleotide nucleotidyltransferase activity
CBR69_RS02855	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBR69_RS02865	COG1183	phosphatidylcholine synthase activity
CBR69_RS02870	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR69_RS02875	COG0440	acetolactate synthase activity
CBR69_RS02880	COG0028	Belongs to the TPP enzyme family
CBR69_RS02885	COG1289	transmembrane transporter activity
CBR69_RS02890	COG3022	response to hydroperoxide
CBR69_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS02965	COG1309	transcriptional regulator
CBR69_RS02980	COG2186	Transcriptional regulator
CBR69_RS02985	COG4638	Rieske (2fe-2S)
CBR69_RS02990	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CBR69_RS02995	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS03050	COG2095	MarC family integral membrane protein
CBR69_RS03060	COG3447	MASE1 domain protein
CBR69_RS03060	COG5002	protein histidine kinase activity
CBR69_RS03060	COG5001	Diguanylate cyclase
CBR69_RS03080	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBR69_RS03090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBR69_RS03105	COG0601	transmembrane transport
CBR69_RS03125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CBR69_RS03125	COG0517	IMP dehydrogenase activity
CBR69_RS03130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR69_RS03140	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CBR69_RS03145	COG1674	ftsk spoiiie
CBR69_RS03150	COG0492	ferredoxin-NADP+ reductase activity
CBR69_RS03155	COG1193	negative regulation of DNA recombination
CBR69_RS03165	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBR69_RS03180	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CBR69_RS03185	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CBR69_RS03190	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
CBR69_RS03195	COG2205	protein histidine kinase activity
CBR69_RS03200	COG0745	RESPONSE REGULATOR receiver
CBR69_RS03215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR69_RS03240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBR69_RS03255	COG0612	Peptidase, M16
CBR69_RS03260	COG0484	heat shock protein binding
CBR69_RS03265	COG0443	Heat shock 70 kDa protein
CBR69_RS03275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBR69_RS03285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CBR69_RS03290	COG1420	regulation of RNA biosynthetic process
CBR69_RS03295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CBR69_RS03300	COG0497	DNA recombination
CBR69_RS03305	COG0735	belongs to the Fur family
CBR69_RS03310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR69_RS03335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR69_RS03370	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS03390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CBR69_RS03395	COG1802	Transcriptional regulator
CBR69_RS03400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR69_RS03405	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBR69_RS03410	COG1335	isochorismatase
CBR69_RS03415	COG0523	cobalamin synthesis protein
CBR69_RS03450	COG0583	DNA-binding transcription factor activity
CBR69_RS03460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBR69_RS03465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CBR69_RS03470	COG0167	dihydroorotate dehydrogenase activity
CBR69_RS03485	COG1414	Transcriptional regulator
CBR69_RS03490	COG1058	Belongs to the CinA family
CBR69_RS03490	COG1546	Belongs to the CinA family
CBR69_RS03505	COG0513	Belongs to the DEAD box helicase family
CBR69_RS03530	COG0429	hydrolase of the alpha beta-hydrolase fold
CBR69_RS03535	COG4783	chaperone-mediated protein folding
CBR69_RS03555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBR69_RS03570	COG0006	proline dipeptidase activity
CBR69_RS03580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS03600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CBR69_RS03605	COG0632	four-way junction helicase activity
CBR69_RS03615	COG0702	epimerase
CBR69_RS03620	COG2255	four-way junction helicase activity
CBR69_RS03625	COG0514	ATP-dependent DNA helicase (RecQ)
CBR69_RS03645	COG1294	oxidase, subunit
CBR69_RS03655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR69_RS03660	COG0850	regulation of cytokinetic process
CBR69_RS03665	COG2894	cell division
CBR69_RS03670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBR69_RS03685	COG0488	(ABC) transporter
CBR69_RS03700	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS03705	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS03710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS03715	COG0601	transmembrane transport
CBR69_RS03725	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS03730	COG0583	DNA-binding transcription factor activity
CBR69_RS03735	COG1802	Transcriptional regulator
CBR69_RS03740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR69_RS03750	COG1024	Enoyl-CoA hydratase
CBR69_RS03775	COG1137	ATPase activity
CBR69_RS03785	COG0154	amidase activity
CBR69_RS03790	COG1368	sulfuric ester hydrolase activity
CBR69_RS03800	COG3685	Protein conserved in bacteria
CBR69_RS03810	COG1686	Belongs to the peptidase S11 family
CBR69_RS03830	COG2832	Protein of unknown function (DUF454)
CBR69_RS03845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR69_RS03875	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CBR69_RS03880	COG1802	Transcriptional regulator
CBR69_RS03885	COG0747	negative chemotaxis
CBR69_RS03890	COG0601	transmembrane transport
CBR69_RS03895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS03900	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS03905	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS03915	COG4191	Histidine kinase
CBR69_RS03915	COG0745	RESPONSE REGULATOR receiver
CBR69_RS03915	COG2205	protein histidine kinase activity
CBR69_RS03920	COG4566	intracellular signal transduction
CBR69_RS03950	COG0477	Major facilitator Superfamily
CBR69_RS03955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS03965	COG0583	DNA-binding transcription factor activity
CBR69_RS03970	COG1414	Transcriptional regulator
CBR69_RS03975	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS03980	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR69_RS03985	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR69_RS03990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR69_RS03995	COG0583	DNA-binding transcription factor activity
CBR69_RS04000	COG3485	protocatechuate 3,4-dioxygenase
CBR69_RS04005	COG3485	protocatechuate 3,4-dioxygenase
CBR69_RS04015	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR69_RS04035	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS04040	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS04065	COG0683	leucine binding
CBR69_RS04090	COG0028	Belongs to the TPP enzyme family
CBR69_RS04095	COG1802	Transcriptional regulator
CBR69_RS04100	COG1802	Transcriptional regulator
CBR69_RS04105	COG0513	Belongs to the DEAD box helicase family
CBR69_RS04115	COG1595	DNA-templated transcription, initiation
CBR69_RS04125	COG0583	DNA-binding transcription factor activity
CBR69_RS04140	COG4774	siderophore transport
CBR69_RS04150	COG1595	DNA-templated transcription, initiation
CBR69_RS04165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS04190	COG0657	acetylesterase activity
CBR69_RS04200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR69_RS04205	COG4569	acetaldehyde dehydrogenase (acetylating) activity
CBR69_RS04215	COG3971	2-oxopent-4-enoate hydratase activity
CBR69_RS04250	COG0459	protein refolding
CBR69_RS04265	COG0583	DNA-binding transcription factor activity
CBR69_RS04275	COG2226	methyltransferase
CBR69_RS04275	COG1073	alpha beta
CBR69_RS04300	COG1175	transmembrane transport
CBR69_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS04330	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBR69_RS04350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBR69_RS04355	COG0459	protein refolding
CBR69_RS04365	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBR69_RS04370	COG1252	NADH dehydrogenase
CBR69_RS04375	COG0284	orotidine-5'-phosphate decarboxylase activity
CBR69_RS04385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBR69_RS04395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR69_RS04400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBR69_RS04430	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS04475	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBR69_RS04480	COG3639	organic phosphonate transmembrane transporter activity
CBR69_RS04485	COG3639	organic phosphonate transmembrane transporter activity
CBR69_RS04500	COG0742	ribosomal rna small subunit methyltransferase
CBR69_RS04505	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBR69_RS04510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBR69_RS04515	COG3135	benzoate transporter
CBR69_RS04555	COG2188	Transcriptional regulator
CBR69_RS04560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS04565	COG1024	Enoyl-CoA hydratase
CBR69_RS04570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR69_RS04590	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS04595	COG2814	Major facilitator Superfamily
CBR69_RS04615	COG0012	GTP binding
CBR69_RS04625	COG0193	aminoacyl-tRNA hydrolase activity
CBR69_RS04630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBR69_RS04635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBR69_RS04645	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBR69_RS04650	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CBR69_RS04660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBR69_RS04670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS04685	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR69_RS04695	COG1368	sulfuric ester hydrolase activity
CBR69_RS04700	COG2186	Transcriptional regulator
CBR69_RS04705	COG5000	phosphorelay sensor kinase activity
CBR69_RS04705	COG5002	protein histidine kinase activity
CBR69_RS04710	COG0745	RESPONSE REGULATOR receiver
CBR69_RS04715	COG0277	FAD linked oxidase domain protein
CBR69_RS04730	COG0166	Belongs to the GPI family
CBR69_RS04735	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS04740	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS04755	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS04770	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR69_RS04775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR69_RS04780	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CBR69_RS04800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR69_RS04805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS04820	COG0747	negative chemotaxis
CBR69_RS04825	COG0601	transmembrane transport
CBR69_RS04830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS04835	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS04850	COG5339	Protein conserved in bacteria
CBR69_RS04855	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR69_RS04855	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CBR69_RS04860	COG0509	glycine decarboxylation via glycine cleavage system
CBR69_RS04865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CBR69_RS04875	COG0371	Dehydrogenase
CBR69_RS04900	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS04915	COG2081	HI0933 family
CBR69_RS04930	COG1214	PFAM Peptidase M22, glycoprotease
CBR69_RS04930	COG0456	acetyltransferase
CBR69_RS04935	COG0717	Belongs to the dCTP deaminase family
CBR69_RS04950	COG0489	protein tyrosine kinase activity
CBR69_RS04960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR69_RS04960	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR69_RS04965	COG1054	Belongs to the UPF0176 family
CBR69_RS04990	COG3539	Fimbrial protein
CBR69_RS04995	COG0010	Belongs to the arginase family
CBR69_RS05010	COG3842	ATPase activity
CBR69_RS05015	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR69_RS05020	COG1177	transmembrane transport
CBR69_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05060	COG2084	Dehydrogenase
CBR69_RS05065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR69_RS05100	COG1073	alpha beta
CBR69_RS05100	COG2226	methyltransferase
CBR69_RS05120	COG2423	ornithine cyclodeaminase activity
CBR69_RS05135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS05165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS05170	COG0765	amino acid transport
CBR69_RS05175	COG0765	amino acid transport
CBR69_RS05185	COG0583	DNA-binding transcription factor activity
CBR69_RS05190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR69_RS05195	COG0625	glutathione transferase activity
CBR69_RS05215	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR69_RS05220	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS05225	COG1309	transcriptional regulator
CBR69_RS05260	COG1309	transcriptional regulator
CBR69_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05270	COG0583	DNA-binding transcription factor activity
CBR69_RS05275	COG2072	flavoprotein involved in K transport
CBR69_RS05320	COG0426	domain, Protein
CBR69_RS05320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR69_RS05325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR69_RS05330	COG0583	DNA-binding transcription factor activity
CBR69_RS05335	COG3386	PFAM SMP-30 Gluconolaconase
CBR69_RS05340	COG1024	Enoyl-CoA hydratase
CBR69_RS05350	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS05365	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05380	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR69_RS05400	COG0583	DNA-binding transcription factor activity
CBR69_RS05425	COG3119	arylsulfatase activity
CBR69_RS05495	COG3077	Addiction module antitoxin, RelB DinJ family
CBR69_RS05695	COG0583	DNA-binding transcription factor activity
CBR69_RS05705	COG2814	Major facilitator Superfamily
CBR69_RS05735	COG2267	carboxylic ester hydrolase activity
CBR69_RS05740	COG0596	Alpha beta hydrolase
CBR69_RS05745	COG0583	DNA-binding transcription factor activity
CBR69_RS05760	COG0024	Methionine aminopeptidase
CBR69_RS05765	COG2267	carboxylic ester hydrolase activity
CBR69_RS05770	COG0583	DNA-binding transcription factor activity
CBR69_RS05785	COG0583	DNA-binding transcription factor activity
CBR69_RS05790	COG0596	Alpha beta hydrolase
CBR69_RS05800	COG0066	3-isopropylmalate dehydratase activity
CBR69_RS05805	COG1309	transcriptional regulator
CBR69_RS05810	COG2814	Major facilitator Superfamily
CBR69_RS05820	COG2207	Transcriptional regulator
CBR69_RS05825	COG4221	oxidoreductase activity
CBR69_RS05830	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS05845	COG3039	Transposase
CBR69_RS05900	COG0492	ferredoxin-NADP+ reductase activity
CBR69_RS05920	COG0582	viral genome integration into host DNA
CBR69_RS05935	COG0277	FAD linked oxidase domain protein
CBR69_RS05940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR69_RS05945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR69_RS05970	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS05975	COG0583	DNA-binding transcription factor activity
CBR69_RS05985	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CBR69_RS06000	COG1652	LysM domain
CBR69_RS06005	COG0560	Phosphoserine phosphatase
CBR69_RS06010	COG0583	DNA-binding transcription factor activity
CBR69_RS06015	COG3842	ATPase activity
CBR69_RS06020	COG1178	ABC-type Fe3 transport system permease component
CBR69_RS06030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBR69_RS06035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR69_RS06050	COG0625	glutathione transferase activity
CBR69_RS06080	COG4336	lyase activity
CBR69_RS06090	COG1414	Transcriptional regulator
CBR69_RS06095	COG3734	2-keto-3-deoxy-galactonokinase
CBR69_RS06100	COG0800	Aldolase
CBR69_RS06105	COG4948	Mandelate Racemase Muconate Lactonizing
CBR69_RS06110	COG2271	Major facilitator Superfamily
CBR69_RS06115	COG0326	Molecular chaperone. Has ATPase activity
CBR69_RS06120	COG2233	PERMEase
CBR69_RS06195	COG3284	Transcriptional regulator
CBR69_RS06220	COG0509	glycine decarboxylation via glycine cleavage system
CBR69_RS06225	COG0022	dehydrogenase e1 component
CBR69_RS06230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBR69_RS06245	COG0235	Class ii aldolase
CBR69_RS06255	COG0436	Aminotransferase
CBR69_RS06335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBR69_RS06340	COG4774	siderophore transport
CBR69_RS06345	COG3712	iron ion homeostasis
CBR69_RS06350	COG1595	DNA-templated transcription, initiation
CBR69_RS06355	COG5285	phytanoyl-CoA dioxygenase
CBR69_RS06360	COG0628	permease
CBR69_RS06365	COG0583	DNA-binding transcription factor activity
CBR69_RS06370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS06390	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CBR69_RS06400	COG3539	Fimbrial protein
CBR69_RS06405	COG0129	dihydroxy-acid dehydratase activity
CBR69_RS06425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBR69_RS06430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CBR69_RS06435	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS06440	COG2031	fatty acid transporter
CBR69_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS06450	COG1414	Transcriptional regulator
CBR69_RS06460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CBR69_RS06465	COG4829	muconolactone delta-isomerase
CBR69_RS06475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR69_RS06495	COG0288	reversible hydration of carbon dioxide
CBR69_RS06500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR69_RS06520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CBR69_RS06525	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR69_RS06530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBR69_RS06535	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CBR69_RS06560	COG0659	secondary active sulfate transmembrane transporter activity
CBR69_RS06590	COG0683	leucine binding
CBR69_RS06595	COG0154	amidase activity
CBR69_RS06620	COG0142	geranyltranstransferase activity
CBR69_RS06625	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBR69_RS06630	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBR69_RS06635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBR69_RS06640	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CBR69_RS06660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR69_RS06660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBR69_RS06665	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBR69_RS06680	COG0861	Integral membrane protein TerC family
CBR69_RS06685	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS06700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBR69_RS06705	COG0793	Belongs to the peptidase S41A family
CBR69_RS06710	COG4942	peptidase
CBR69_RS06715	COG0588	phosphoglycerate mutase activity
CBR69_RS06725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR69_RS06730	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBR69_RS06735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBR69_RS06755	COG2226	methyltransferase
CBR69_RS06760	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CBR69_RS06765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CBR69_RS06770	COG0569	domain protein
CBR69_RS06775	COG2204	response regulator
CBR69_RS06780	COG5000	phosphorelay sensor kinase activity
CBR69_RS06790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR69_RS06790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR69_RS06800	COG0583	DNA-binding transcription factor activity
CBR69_RS06805	COG2814	Major facilitator Superfamily
CBR69_RS06810	COG0583	DNA-binding transcription factor activity
CBR69_RS06820	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR69_RS06825	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS06830	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS06835	COG2072	flavoprotein involved in K transport
CBR69_RS06840	COG2267	carboxylic ester hydrolase activity
CBR69_RS06870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBR69_RS06875	COG0583	DNA-binding transcription factor activity
CBR69_RS06880	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS06910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS06915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR69_RS06930	COG0546	phosphoglycolate phosphatase activity
CBR69_RS06940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR69_RS06945	COG0242	peptide deformylase activity
CBR69_RS06955	COG1522	sequence-specific DNA binding
CBR69_RS06960	COG2879	small protein
CBR69_RS06965	COG1966	Carbon starvation protein
CBR69_RS06980	COG0758	DNA mediated transformation
CBR69_RS06995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS07000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR69_RS07005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CBR69_RS07075	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS07110	COG0640	Transcriptional regulator
CBR69_RS07145	COG0735	belongs to the Fur family
CBR69_RS07150	COG2207	Transcriptional regulator
CBR69_RS07165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR69_RS07170	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBR69_RS07175	COG0513	Belongs to the DEAD box helicase family
CBR69_RS07195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBR69_RS07200	COG2308	Evidence 4 Homologs of previously reported genes of
CBR69_RS07210	COG1305	Transglutaminase-like
CBR69_RS07230	COG3220	belongs to the UPF0276 family
CBR69_RS07245	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBR69_RS07250	COG1950	PFAM Membrane protein of
CBR69_RS07275	COG0066	3-isopropylmalate dehydratase activity
CBR69_RS07290	COG0583	DNA-binding transcription factor activity
CBR69_RS07295	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBR69_RS07305	COG1560	Kdo2-lipid A biosynthetic process
CBR69_RS07310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBR69_RS07320	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CBR69_RS07345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CBR69_RS07355	COG0735	belongs to the Fur family
CBR69_RS07360	COG0523	cobalamin synthesis protein
CBR69_RS07370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBR69_RS07375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBR69_RS07385	COG2096	Adenosyltransferase
CBR69_RS07390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CBR69_RS07395	COG0321	lipoyl(octanoyl) transferase activity
CBR69_RS07400	COG2921	Belongs to the UPF0250 family
CBR69_RS07410	COG1686	Belongs to the peptidase S11 family
CBR69_RS07430	COG1127	ABC transporter
CBR69_RS07435	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR69_RS07445	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBR69_RS07455	COG0859	PFAM glycosyl transferase family 9
CBR69_RS07490	COG0477	Major facilitator Superfamily
CBR69_RS07500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR69_RS07505	COG3568	Endonuclease Exonuclease Phosphatase
CBR69_RS07510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBR69_RS07540	COG0531	amino acid
CBR69_RS07545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR69_RS07550	COG1956	GAF domain-containing protein
CBR69_RS07555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR69_RS07560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CBR69_RS07570	COG1129	ABC transporter
CBR69_RS07580	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS07590	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS07600	COG2186	Transcriptional regulator
CBR69_RS07605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CBR69_RS07610	COG3842	ATPase activity
CBR69_RS07615	COG1175	transmembrane transport
CBR69_RS07665	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBR69_RS07670	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR69_RS07690	COG0367	asparagine synthase
CBR69_RS07695	COG1088	dTDP-glucose 4,6-dehydratase activity
CBR69_RS07700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBR69_RS07710	COG0367	asparagine synthase
CBR69_RS07720	COG2226	methyltransferase
CBR69_RS07750	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR69_RS07760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBR69_RS07765	COG0367	asparagine synthase
CBR69_RS07770	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBR69_RS07775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBR69_RS07785	COG2814	Major facilitator Superfamily
CBR69_RS07805	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CBR69_RS07810	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CBR69_RS07815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR69_RS07825	COG1965	Belongs to the frataxin family
CBR69_RS07840	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBR69_RS07845	COG1333	cytochrome c biogenesis protein
CBR69_RS07855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBR69_RS07870	COG4232	protein-disulfide reductase activity
CBR69_RS07875	COG1324	tolerance protein
CBR69_RS07885	COG0203	ribosomal protein L17
CBR69_RS07890	COG0202	RNA polymerase activity
CBR69_RS07895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBR69_RS07900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBR69_RS07905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBR69_RS07910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBR69_RS07915	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBR69_RS07920	COG0201	protein transport
CBR69_RS07925	COG0200	Binds to the 23S rRNA
CBR69_RS07930	COG1841	ribosomal large subunit assembly
CBR69_RS07935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBR69_RS07940	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBR69_RS07945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBR69_RS07950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBR69_RS07955	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBR69_RS07960	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBR69_RS07965	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBR69_RS07970	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBR69_RS07995	COG2267	carboxylic ester hydrolase activity
CBR69_RS08010	COG1131	(ABC) transporter
CBR69_RS08025	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBR69_RS08030	COG0255	Belongs to the universal ribosomal protein uL29 family
CBR69_RS08035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBR69_RS08040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBR69_RS08045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBR69_RS08050	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBR69_RS08055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBR69_RS08060	COG0089	rRNA binding
CBR69_RS08065	COG0088	Forms part of the polypeptide exit tunnel
CBR69_RS08070	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBR69_RS08075	COG0051	transcription antitermination factor activity, RNA binding
CBR69_RS08080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR69_RS08085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR69_RS08090	COG0049	tRNA binding
CBR69_RS08095	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBR69_RS08130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBR69_RS08135	COG0085	RNA polymerase activity
CBR69_RS08140	COG0222	ribosome binding
CBR69_RS08145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBR69_RS08150	COG0081	regulation of translation
CBR69_RS08155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBR69_RS08165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBR69_RS08175	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBR69_RS08195	COG0252	asparaginase activity
CBR69_RS08200	COG1475	DNA binding
CBR69_RS08205	COG1192	Involved in chromosome partitioning
CBR69_RS08210	COG0357	Ribosomal RNA small subunit methyltransferase G
CBR69_RS08215	COG0445	tRNA wobble uridine modification
CBR69_RS08220	COG1278	Cold shock
CBR69_RS08225	COG0436	Aminotransferase
CBR69_RS08235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR69_RS08240	COG0583	DNA-binding transcription factor activity
CBR69_RS08290	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS08295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS08305	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS08310	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR69_RS08320	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CBR69_RS08330	COG1505	serine-type exopeptidase activity
CBR69_RS08335	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR69_RS08345	COG0601	transmembrane transport
CBR69_RS08350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS08355	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS08360	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS08365	COG1473	amidohydrolase
CBR69_RS08370	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CBR69_RS08375	COG0706	membrane insertase activity
CBR69_RS08380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBR69_RS08385	COG0594	ribonuclease P activity
CBR69_RS08390	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBR69_RS08395	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBR69_RS08400	COG0592	DNA-directed DNA polymerase activity
CBR69_RS08415	COG1309	transcriptional regulator
CBR69_RS08420	COG1254	Belongs to the acylphosphatase family
CBR69_RS08425	COG1304	FMN binding
CBR69_RS08430	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CBR69_RS08445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS08450	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS08475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS08485	COG0625	glutathione transferase activity
CBR69_RS08490	COG0402	S-adenosylhomocysteine deaminase activity
CBR69_RS08495	COG1079	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS08500	COG4603	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS08505	COG3845	ABC transporter
CBR69_RS08520	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR69_RS08525	COG2910	NAD(P)H-binding
CBR69_RS08545	COG0702	epimerase
CBR69_RS08555	COG3781	membrane
CBR69_RS08560	COG1522	sequence-specific DNA binding
CBR69_RS08565	COG0028	Belongs to the TPP enzyme family
CBR69_RS08575	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS08580	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS08585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR69_RS08590	COG3842	ATPase activity
CBR69_RS08610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR69_RS08615	COG2922	Belongs to the Smg family
CBR69_RS08620	COG1629	transport
CBR69_RS08630	COG2358	TRAP transporter, solute receptor (TAXI family
CBR69_RS08640	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR69_RS08655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CBR69_RS08660	COG0183	Belongs to the thiolase family
CBR69_RS08665	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS08670	COG1473	amidohydrolase
CBR69_RS08700	COG2200	EAL domain
CBR69_RS08705	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR69_RS08715	COG0018	arginyl-trna synthetase
CBR69_RS08730	COG0395	ABC-type sugar transport system, permease component
CBR69_RS08735	COG1175	transmembrane transport
CBR69_RS08740	COG1653	transport
CBR69_RS08745	COG3842	ATPase activity
CBR69_RS08750	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR69_RS08755	COG3842	ATPase activity
CBR69_RS08780	COG0154	amidase activity
CBR69_RS08785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR69_RS08795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR69_RS08805	COG0583	DNA-binding transcription factor activity
CBR69_RS08825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBR69_RS08830	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS08835	COG0513	Belongs to the DEAD box helicase family
CBR69_RS08845	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CBR69_RS08855	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS08860	COG0601	transmembrane transport
CBR69_RS08870	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBR69_RS08890	COG0697	spore germination
CBR69_RS08905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBR69_RS08915	COG2969	positive regulation of protein catabolic process
CBR69_RS08920	COG0625	glutathione transferase activity
CBR69_RS08925	COG2857	Cytochrome c1
CBR69_RS08930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBR69_RS08935	COG0723	plastoquinol--plastocyanin reductase activity
CBR69_RS08940	COG1970	mechanosensitive ion channel activity
CBR69_RS08945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBR69_RS08950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR69_RS08960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR69_RS08965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBR69_RS08970	COG0537	adenosine 5'-monophosphoramidase activity
CBR69_RS08975	COG0140	phosphoribosyl-ATP diphosphatase activity
CBR69_RS08980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBR69_RS08985	COG0107	imidazoleglycerol-phosphate synthase activity
CBR69_RS08990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBR69_RS09000	COG0131	Imidazoleglycerol-phosphate dehydratase
CBR69_RS09005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR69_RS09010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CBR69_RS09015	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBR69_RS09020	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBR69_RS09025	COG0271	Belongs to the BolA IbaG family
CBR69_RS09030	COG0842	Transport permease protein
CBR69_RS09035	COG1131	(ABC) transporter
CBR69_RS09050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CBR69_RS09055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBR69_RS09060	COG1127	ABC transporter
CBR69_RS09065	COG3047	cAMP biosynthetic process
CBR69_RS09075	COG0067	glutamate synthase
CBR69_RS09075	COG0070	glutamate synthase
CBR69_RS09075	COG0069	glutamate synthase activity
CBR69_RS09090	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CBR69_RS09105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBR69_RS09110	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CBR69_RS09120	COG1609	Transcriptional regulator
CBR69_RS09125	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
CBR69_RS09135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR69_RS09175	COG0109	protoheme IX farnesyltransferase activity
CBR69_RS09180	COG1999	signal sequence binding
CBR69_RS09200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBR69_RS09205	COG2814	Major facilitator Superfamily
CBR69_RS09220	COG1522	sequence-specific DNA binding
CBR69_RS09320	COG2124	cytochrome p450
CBR69_RS09355	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS09365	COG1902	pentaerythritol trinitrate reductase activity
CBR69_RS09440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR69_RS09450	COG1671	Belongs to the UPF0178 family
CBR69_RS09455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS09480	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBR69_RS09485	COG0443	Heat shock 70 kDa protein
CBR69_RS09495	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS09520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CBR69_RS09520	COG2169	Transcriptional regulator
CBR69_RS09535	COG0583	DNA-binding transcription factor activity
CBR69_RS09545	COG1473	amidohydrolase
CBR69_RS09550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR69_RS09555	COG1335	isochorismatase
CBR69_RS09565	COG1683	Conserved Protein
CBR69_RS09570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS09585	COG1120	ATPase activity
CBR69_RS09590	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBR69_RS09595	COG4558	Periplasmic binding protein
CBR69_RS09600	COG3720	iron ion transport
CBR69_RS09610	COG3712	iron ion homeostasis
CBR69_RS09615	COG1595	DNA-templated transcription, initiation
CBR69_RS09645	COG1607	acyl-coa hydrolase
CBR69_RS09660	COG0437	4 iron, 4 sulfur cluster binding
CBR69_RS09665	COG2864	formate dehydrogenase
CBR69_RS09680	COG3276	selenocysteine insertion sequence binding
CBR69_RS09700	COG0583	DNA-binding transcription factor activity
CBR69_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS09720	COG0134	indole-3-glycerol-phosphate synthase activity
CBR69_RS09725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBR69_RS09730	COG0512	Glutamine amidotransferase of anthranilate synthase
CBR69_RS09740	COG0546	phosphoglycolate phosphatase activity
CBR69_RS09745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBR69_RS09750	COG2967	ApaG domain
CBR69_RS09755	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CBR69_RS09760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS09765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBR69_RS09775	COG0037	tRNA processing
CBR69_RS09795	COG1024	Enoyl-CoA hydratase
CBR69_RS09810	COG0356	it plays a direct role in the translocation of protons across the membrane
CBR69_RS09820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBR69_RS09825	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBR69_RS09830	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBR69_RS09835	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBR69_RS09840	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBR69_RS09845	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBR69_RS09855	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBR69_RS09860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBR69_RS09865	COG0210	DNA helicase
CBR69_RS09880	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS09885	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS09890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS09895	COG0601	transmembrane transport
CBR69_RS09905	COG0747	negative chemotaxis
CBR69_RS09915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBR69_RS09920	COG1024	Enoyl-CoA hydratase
CBR69_RS09925	COG1024	Enoyl-CoA hydratase
CBR69_RS09930	COG2070	2-Nitropropane dioxygenase
CBR69_RS09935	COG1309	transcriptional regulator
CBR69_RS09940	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS09950	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS09955	COG3245	cytochrome
CBR69_RS09980	COG2918	glutathione biosynthetic process
CBR69_RS10000	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR69_RS10005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR69_RS10010	COG2813	Specifically methylates the guanine in position
CBR69_RS10010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBR69_RS10015	COG2223	nitrite transmembrane transporter activity
CBR69_RS10020	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS10030	COG2860	membrane
CBR69_RS10035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR69_RS10040	COG0708	Exodeoxyribonuclease III
CBR69_RS10045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBR69_RS10050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR69_RS10055	COG0154	amidase activity
CBR69_RS10060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBR69_RS10065	COG1077	Cell shape determining protein MreB Mrl
CBR69_RS10070	COG1792	Involved in formation and maintenance of cell shape
CBR69_RS10080	COG0768	penicillin binding
CBR69_RS10085	COG0772	Belongs to the SEDS family
CBR69_RS10090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
CBR69_RS10095	COG0471	metal ion transport
CBR69_RS10100	COG1309	transcriptional regulator
CBR69_RS10110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR69_RS10125	COG2823	Periplasmic or secreted lipoprotein
CBR69_RS10130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CBR69_RS10135	COG0792	nuclease activity
CBR69_RS10155	COG1660	Displays ATPase and GTPase activities
CBR69_RS10170	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CBR69_RS10180	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBR69_RS10185	COG1137	ATPase activity
CBR69_RS10200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CBR69_RS10210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CBR69_RS10225	COG1294	oxidase, subunit
CBR69_RS10235	COG4988	ABC transporter
CBR69_RS10240	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CBR69_RS10245	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CBR69_RS10260	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS10265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBR69_RS10270	COG1238	metal cluster binding
CBR69_RS10280	COG1802	Transcriptional regulator
CBR69_RS10290	COG1984	allophanate hydrolase subunit 2
CBR69_RS10295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CBR69_RS10310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR69_RS10325	COG2132	Multicopper oxidase
CBR69_RS10335	COG5002	protein histidine kinase activity
CBR69_RS10345	COG5002	protein histidine kinase activity
CBR69_RS10350	COG0745	RESPONSE REGULATOR receiver
CBR69_RS10355	COG2226	methyltransferase
CBR69_RS10370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR69_RS10375	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS10410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR69_RS10445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR69_RS10460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBR69_RS10470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CBR69_RS10475	COG1538	Outer membrane efflux protein
CBR69_RS10480	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR69_RS10485	COG0351	phosphomethylpyrimidine kinase
CBR69_RS10490	COG2022	thiamine diphosphate biosynthetic process
CBR69_RS10500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CBR69_RS10505	COG4206	TonB-dependent receptor
CBR69_RS10515	COG2226	methyltransferase
CBR69_RS10530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR69_RS10545	COG1194	a g-specific adenine glycosylase
CBR69_RS10555	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CBR69_RS10560	COG2177	Part of the ABC transporter FtsEX involved in
CBR69_RS10565	COG2884	Cell division ATP-binding protein ftsE
CBR69_RS10570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS10575	COG4597	amino acid ABC transporter
CBR69_RS10580	COG0765	amino acid transport
CBR69_RS10585	COG1126	abc transporter atp-binding protein
CBR69_RS10605	COG0477	Major facilitator Superfamily
CBR69_RS10615	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CBR69_RS10620	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBR69_RS10635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBR69_RS10640	COG0237	dephospho-CoA kinase activity
CBR69_RS10645	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CBR69_RS10670	COG3539	Fimbrial protein
CBR69_RS10675	COG2816	NAD+ diphosphatase activity
CBR69_RS10685	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBR69_RS10720	COG0411	ABC transporter
CBR69_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS10760	COG1024	Enoyl-CoA hydratase
CBR69_RS10790	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBR69_RS10795	COG0352	thiamine-phosphate diphosphorylase activity
CBR69_RS10810	COG1678	Uncharacterized ACR, COG1678
CBR69_RS10815	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBR69_RS10840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR69_RS10850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBR69_RS10855	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CBR69_RS10865	COG0557	exoribonuclease II activity
CBR69_RS10870	COG3150	esterase
CBR69_RS10875	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR69_RS10880	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR69_RS10885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBR69_RS10890	COG0511	ligase activity, forming carbon-carbon bonds
CBR69_RS10895	COG0439	Biotin carboxylase
CBR69_RS10900	COG2264	protein methyltransferase activity
CBR69_RS10910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBR69_RS10935	COG1696	Membrane protein involved in D-alanine export
CBR69_RS10940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CBR69_RS10970	COG1522	sequence-specific DNA binding
CBR69_RS10980	COG2814	Major facilitator Superfamily
CBR69_RS10985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBR69_RS10990	COG1042	CoA-binding domain protein
CBR69_RS10990	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR69_RS10990	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR69_RS10990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR69_RS10990	COG1042	CoA-binding domain protein
CBR69_RS10990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR69_RS11040	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBR69_RS11065	COG3028	Belongs to the UPF0307 family
CBR69_RS11070	COG0312	modulator of DNA gyrase
CBR69_RS11080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR69_RS11085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBR69_RS11090	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBR69_RS11095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR69_RS11105	COG0316	Belongs to the HesB IscA family
CBR69_RS11110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CBR69_RS11120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBR69_RS11130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBR69_RS11135	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBR69_RS11145	COG1335	isochorismatase
CBR69_RS11150	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR69_RS11150	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBR69_RS11160	COG2766	serine protein kinase
CBR69_RS11165	COG2718	Belongs to the UPF0229 family
CBR69_RS11170	COG2719	SpoVR family
CBR69_RS11190	COG4948	Mandelate Racemase Muconate Lactonizing
CBR69_RS11205	COG0477	Major facilitator Superfamily
CBR69_RS11215	COG0583	DNA-binding transcription factor activity
CBR69_RS11230	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR69_RS11235	COG0251	oxidation-reduction process
CBR69_RS11240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CBR69_RS11245	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CBR69_RS11260	COG0165	Argininosuccinate lyase
CBR69_RS11270	COG3707	response regulator
CBR69_RS11280	COG0515	serine threonine protein kinase
CBR69_RS11285	COG2116	formate transmembrane transporter activity
CBR69_RS11295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBR69_RS11295	COG2146	nitrite reductase [NAD(P)H] activity
CBR69_RS11300	COG0589	response to stress
CBR69_RS11315	COG2816	NAD+ diphosphatase activity
CBR69_RS11320	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS11360	COG2979	Protein of unknown function (DUF533)
CBR69_RS11370	COG0741	lytic transglycosylase activity
CBR69_RS11370	COG1388	LysM domain
CBR69_RS11375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBR69_RS11380	COG2226	methyltransferase
CBR69_RS11385	COG0328	RNA-DNA hybrid ribonuclease activity
CBR69_RS11395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR69_RS11400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CBR69_RS11410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS11415	COG1129	ABC transporter
CBR69_RS11415	COG0842	Transport permease protein
CBR69_RS11420	COG0842	Transport permease protein
CBR69_RS11440	COG0463	Glycosyl transferase, family 2
CBR69_RS11445	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBR69_RS11460	COG1073	alpha beta
CBR69_RS11470	COG0697	spore germination
CBR69_RS11475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR69_RS11490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBR69_RS11500	COG1522	sequence-specific DNA binding
CBR69_RS11525	COG0823	Involved in the tonB-independent uptake of proteins
CBR69_RS11535	COG0848	biopolymer transport protein
CBR69_RS11540	COG0811	peptide transport
CBR69_RS11545	COG0824	Thioesterase
CBR69_RS11550	COG0442	prolyl-tRNA aminoacylation
CBR69_RS11580	COG1414	Transcriptional regulator
CBR69_RS11585	COG1024	Enoyl-CoA hydratase
CBR69_RS11600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CBR69_RS11605	COG2084	Dehydrogenase
CBR69_RS11610	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS11615	COG1309	transcriptional regulator
CBR69_RS11650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CBR69_RS11655	COG4654	Cytochrome c, class I
CBR69_RS11660	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR69_RS11710	COG1473	amidohydrolase
CBR69_RS11715	COG0418	dihydroorotase activity
CBR69_RS11720	COG0488	(ABC) transporter
CBR69_RS11730	COG2001	Belongs to the MraZ family
CBR69_RS11735	COG0275	rRNA processing
CBR69_RS11740	COG3116	cell division
CBR69_RS11750	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR69_RS11755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBR69_RS11760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBR69_RS11770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBR69_RS11775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBR69_RS11780	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBR69_RS11785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBR69_RS11800	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBR69_RS11815	COG0739	heme binding
CBR69_RS11820	COG0653	protein targeting
CBR69_RS11845	COG1522	sequence-specific DNA binding
CBR69_RS11860	COG2239	Acts as a magnesium transporter
CBR69_RS11870	COG2855	membrane
CBR69_RS11875	COG0583	DNA-binding transcription factor activity
CBR69_RS11880	COG1473	amidohydrolase
CBR69_RS11885	COG0318	PFAM AMP-dependent synthetase and ligase
CBR69_RS11895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR69_RS11895	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CBR69_RS11900	COG1501	Belongs to the glycosyl hydrolase 31 family
CBR69_RS11905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CBR69_RS11910	COG2011	ABC-type metal ion transport system permease component
CBR69_RS11925	COG0300	oxidoreductase activity
CBR69_RS11945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CBR69_RS11950	COG0156	8-amino-7-oxononanoate synthase activity
CBR69_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS11955	COG0604	alcohol dehydrogenase
CBR69_RS11955	COG3321	synthase
CBR69_RS11960	COG0402	S-adenosylhomocysteine deaminase activity
CBR69_RS11985	COG0727	PFAM Uncharacterised protein family (UPF0153)
CBR69_RS11990	COG2818	Glycosylase
CBR69_RS11995	COG2982	Protein involved in outer membrane biogenesis
CBR69_RS12025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CBR69_RS12030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR69_RS12065	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS12080	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS12095	COG0410	ABC transporter
CBR69_RS12115	COG0583	DNA-binding transcription factor activity
CBR69_RS12120	COG0737	Belongs to the 5'-nucleotidase family
CBR69_RS12130	COG4106	trans-aconitate 2-methyltransferase activity
CBR69_RS12135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBR69_RS12145	COG0667	Aldo Keto reductase
CBR69_RS12160	COG2154	pterin-4-alpha-carbinolamine dehydratase
CBR69_RS12170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CBR69_RS12180	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CBR69_RS12185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR69_RS12190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBR69_RS12200	COG1929	Belongs to the glycerate kinase type-1 family
CBR69_RS12205	COG0469	pyruvate kinase activity
CBR69_RS12210	COG0700	Nucleoside recognition
CBR69_RS12215	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS12220	COG0242	peptide deformylase activity
CBR69_RS12240	COG3976	FMN-binding domain protein
CBR69_RS12240	COG1053	succinate dehydrogenase
CBR69_RS12245	COG0583	DNA-binding transcription factor activity
CBR69_RS12255	COG0204	Acyl-transferase
CBR69_RS12260	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR69_RS12265	COG0751	glycine-tRNA ligase activity
CBR69_RS12270	COG0752	glycyl-tRNA synthetase alpha subunit
CBR69_RS12275	COG1024	Enoyl-CoA hydratase
CBR69_RS12285	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CBR69_RS12315	COG0617	tRNA 3'-terminal CCA addition
CBR69_RS12330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBR69_RS12335	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBR69_RS12340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CBR69_RS12345	COG0586	Pfam SNARE associated Golgi protein
CBR69_RS12350	COG3210	domain, Protein
CBR69_RS12350	COG3210	domain, Protein
CBR69_RS12350	COG3064	Membrane
CBR69_RS12350	COG3064	Membrane
CBR69_RS12350	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR69_RS12350	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR69_RS12355	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBR69_RS12365	COG0114	fumarate hydratase activity
CBR69_RS12375	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS12385	COG0405	Gamma-glutamyltransferase
CBR69_RS12395	COG3210	domain, Protein
CBR69_RS12405	COG0579	oxidoreductase
CBR69_RS12410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR69_RS12415	COG0259	pyridoxamine-phosphate oxidase activity
CBR69_RS12430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS12435	COG1136	(ABC) transporter
CBR69_RS12435	COG0577	efflux transmembrane transporter activity
CBR69_RS12440	COG1538	Outer membrane efflux protein
CBR69_RS12445	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBR69_RS12455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR69_RS12480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBR69_RS12505	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS12570	COG0583	DNA-binding transcription factor activity
CBR69_RS12595	COG0427	acetyl-CoA hydrolase
CBR69_RS12600	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS12605	COG2301	Belongs to the HpcH HpaI aldolase family
CBR69_RS12635	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS12640	COG0683	leucine binding
CBR69_RS12650	COG2205	protein histidine kinase activity
CBR69_RS12655	COG3210	domain, Protein
CBR69_RS12665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS12670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBR69_RS12675	COG1538	Outer membrane efflux protein
CBR69_RS12695	COG3258	Cytochrome c
CBR69_RS12700	COG2863	cytochrome
CBR69_RS12720	COG2205	protein histidine kinase activity
CBR69_RS12735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS12740	COG2301	Belongs to the HpcH HpaI aldolase family
CBR69_RS12755	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS12765	COG2814	Major facilitator Superfamily
CBR69_RS12780	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS12785	COG4948	Mandelate Racemase Muconate Lactonizing
CBR69_RS12790	COG0583	DNA-binding transcription factor activity
CBR69_RS12835	COG3585	molybdate ion transport
CBR69_RS12840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR69_RS12850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR69_RS12855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR69_RS12870	COG2188	Transcriptional regulator
CBR69_RS12875	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBR69_RS12885	COG0402	S-adenosylhomocysteine deaminase activity
CBR69_RS12890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CBR69_RS12895	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR69_RS12895	COG0022	dehydrogenase e1 component
CBR69_RS12900	COG1024	Enoyl-CoA hydratase
CBR69_RS12905	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR69_RS12915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR69_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS12950	COG0411	ABC transporter
CBR69_RS12975	COG1309	transcriptional regulator
CBR69_RS12990	COG1024	Enoyl-CoA hydratase
CBR69_RS13010	COG4133	protoheme IX ABC transporter activity
CBR69_RS13015	COG0154	amidase activity
CBR69_RS13025	COG0583	DNA-binding transcription factor activity
CBR69_RS13045	COG2197	response regulator
CBR69_RS13050	COG2814	Major facilitator Superfamily
CBR69_RS13060	COG4774	siderophore transport
CBR69_RS13065	COG3712	iron ion homeostasis
CBR69_RS13070	COG1595	DNA-templated transcription, initiation
CBR69_RS13115	COG0625	glutathione transferase activity
CBR69_RS13125	COG0747	negative chemotaxis
CBR69_RS13130	COG0583	DNA-binding transcription factor activity
CBR69_RS13165	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS13175	COG2207	Transcriptional regulator
CBR69_RS13180	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS13195	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS13200	COG3284	Transcriptional regulator
CBR69_RS13210	COG2814	Major facilitator Superfamily
CBR69_RS13215	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR69_RS13225	COG1959	2 iron, 2 sulfur cluster binding
CBR69_RS13235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR69_RS13240	COG1971	Probably functions as a manganese efflux pump
CBR69_RS13255	COG1360	Flagellar Motor Protein
CBR69_RS13270	COG0840	transmembrane signaling receptor activity
CBR69_RS13290	COG5265	(ABC) transporter
CBR69_RS13305	COG0833	amino acid
CBR69_RS13335	COG0235	Class ii aldolase
CBR69_RS13345	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR69_RS13350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS13355	COG2186	Transcriptional regulator
CBR69_RS13360	COG1024	Enoyl-CoA hydratase
CBR69_RS13375	COG0583	DNA-binding transcription factor activity
CBR69_RS13385	COG2159	amidohydrolase
CBR69_RS13400	COG1301	dicarboxylic acid transport
CBR69_RS13410	COG0148	phosphopyruvate hydratase activity
CBR69_RS13420	COG2814	Major facilitator Superfamily
CBR69_RS13425	COG0583	DNA-binding transcription factor activity
CBR69_RS13470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBR69_RS13480	COG4774	siderophore transport
CBR69_RS13490	COG3128	pkhd-type hydroxylase
CBR69_RS13505	COG3064	Membrane
CBR69_RS13510	COG1408	metallophosphoesterase
CBR69_RS13520	COG0456	acetyltransferase
CBR69_RS13530	COG2610	gluconate transmembrane transporter activity
CBR69_RS13540	COG2070	2-Nitropropane dioxygenase
CBR69_RS13550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CBR69_RS13595	COG1846	Transcriptional regulator
CBR69_RS13610	COG5001	Diguanylate cyclase
CBR69_RS13610	COG3300	MHYT domain
CBR69_RS13640	COG4964	Belongs to the GSP D family
CBR69_RS13690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS13695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBR69_RS13710	COG3384	dioxygenase
CBR69_RS13715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR69_RS13735	COG2176	DNA-directed DNA polymerase activity
CBR69_RS13760	COG4221	oxidoreductase activity
CBR69_RS13770	COG3264	Mechanosensitive ion channel
CBR69_RS13770	COG1511	domain protein
CBR69_RS13775	COG0583	DNA-binding transcription factor activity
CBR69_RS13780	COG0427	acetyl-CoA hydrolase
CBR69_RS13785	COG0583	DNA-binding transcription factor activity
CBR69_RS13835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS13850	COG0154	amidase activity
CBR69_RS13865	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBR69_RS13880	COG0495	leucyl-tRNA aminoacylation
CBR69_RS13885	COG2814	Major facilitator Superfamily
CBR69_RS13890	COG1846	Transcriptional regulator
CBR69_RS13910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBR69_RS13915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBR69_RS13920	COG2814	Major facilitator Superfamily
CBR69_RS13925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBR69_RS13935	COG4176	ABC-type proline glycine betaine transport system permease component
CBR69_RS13950	COG0183	Belongs to the thiolase family
CBR69_RS13970	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR69_RS13970	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CBR69_RS13980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBR69_RS13985	COG1845	cytochrome c oxidase, subunit III
CBR69_RS13990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBR69_RS13995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CBR69_RS14000	COG0477	Major facilitator Superfamily
CBR69_RS14005	COG0428	transporter
CBR69_RS14010	COG0412	Dienelactone hydrolase
CBR69_RS14015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR69_RS14020	COG1283	sodium-dependent phosphate transmembrane transporter activity
CBR69_RS14025	COG1760	l-serine dehydratase
CBR69_RS14030	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBR69_RS14035	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CBR69_RS14045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CBR69_RS14070	COG2311	Membrane
CBR69_RS14080	COG2358	TRAP transporter, solute receptor (TAXI family
CBR69_RS14085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS14100	COG0456	acetyltransferase
CBR69_RS14110	COG0662	Cupin 2, conserved barrel domain protein
CBR69_RS14115	COG5285	phytanoyl-CoA dioxygenase
CBR69_RS14120	COG0633	Ferredoxin
CBR69_RS14120	COG3217	Mosc domain protein beta barrel domain protein
CBR69_RS14125	COG2076	Multidrug Resistance protein
CBR69_RS14130	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBR69_RS14135	COG0543	2 iron, 2 sulfur cluster binding
CBR69_RS14135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR69_RS14140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR69_RS14190	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBR69_RS14195	COG0425	Belongs to the sulfur carrier protein TusA family
CBR69_RS14205	COG0228	four-way junction DNA binding
CBR69_RS14210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBR69_RS14215	COG0336	Belongs to the RNA methyltransferase TrmD family
CBR69_RS14220	COG0525	valine-tRNA ligase activity
CBR69_RS14225	COG0105	UTP biosynthetic process
CBR69_RS14230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBR69_RS14245	COG0124	histidyl-tRNA synthetase
CBR69_RS14250	COG2976	Protein conserved in bacteria
CBR69_RS14255	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR69_RS14260	COG1160	GTP binding
CBR69_RS14265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR69_RS14270	COG1923	regulation of RNA biosynthetic process
CBR69_RS14275	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBR69_RS14280	COG0330	HflC and HflK could
CBR69_RS14285	COG0330	HflC and HflK could
CBR69_RS14290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBR69_RS14295	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBR69_RS14305	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBR69_RS14360	COG2207	Transcriptional regulator
CBR69_RS14370	COG0475	glutathione-regulated potassium exporter activity
CBR69_RS14370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBR69_RS14390	COG0330	HflC and HflK could
CBR69_RS14405	COG0840	transmembrane signaling receptor activity
CBR69_RS14430	COG2201	protein-glutamate methylesterase activity
CBR69_RS14435	COG2203	Gaf domain
CBR69_RS14435	COG3706	GGDEF domain
CBR69_RS14435	COG4251	negative regulation of phosphorylation
CBR69_RS14435	COG5001	Diguanylate cyclase
CBR69_RS14440	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
CBR69_RS14475	COG0583	DNA-binding transcription factor activity
CBR69_RS14490	COG2084	Dehydrogenase
CBR69_RS14500	COG1597	lipid kinase activity
CBR69_RS14500	COG1803	Methylglyoxal synthase
CBR69_RS14510	COG0671	phosphoesterase, PA-phosphatase related
CBR69_RS14530	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS14535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR69_RS14540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR69_RS14545	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR69_RS14550	COG0649	NAD binding
CBR69_RS14555	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CBR69_RS14565	COG1034	ATP synthesis coupled electron transport
CBR69_RS14570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBR69_RS14575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBR69_RS14585	COG0713	ATP synthesis coupled electron transport
CBR69_RS14600	COG1007	ATP synthesis coupled electron transport
CBR69_RS14610	COG0560	Phosphoserine phosphatase
CBR69_RS14615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBR69_RS14620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBR69_RS14625	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBR69_RS14630	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR69_RS14635	COG0450	alkyl hydroperoxide reductase
CBR69_RS14650	COG1214	PFAM Peptidase M22, glycoprotease
CBR69_RS14655	COG1573	uracil-dna glycosylase
CBR69_RS14660	COG0477	Major facilitator Superfamily
CBR69_RS14665	COG1196	nuclear chromosome segregation
CBR69_RS14675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBR69_RS14685	COG0765	amino acid transport
CBR69_RS14690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS14700	COG0625	glutathione transferase activity
CBR69_RS14705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR69_RS14710	COG0271	Belongs to the BolA IbaG family
CBR69_RS14715	COG2917	probably involved in intracellular septation
CBR69_RS14720	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBR69_RS14725	COG1122	ATPase activity
CBR69_RS14730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CBR69_RS14735	COG1268	BioY protein
CBR69_RS14765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CBR69_RS14795	COG0411	ABC transporter
CBR69_RS14800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBR69_RS14805	COG2878	Part of a membrane complex involved in electron transport
CBR69_RS14830	COG0251	oxidation-reduction process
CBR69_RS14840	COG3228	Belongs to the MtfA family
CBR69_RS14845	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR69_RS14865	COG0159	tryptophan synthase activity
CBR69_RS14870	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBR69_RS14875	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CBR69_RS14880	COG1530	ribonuclease E activity
CBR69_RS14885	COG0564	pseudouridine synthase activity
CBR69_RS14890	COG0546	phosphoglycolate phosphatase activity
CBR69_RS14895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CBR69_RS14900	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBR69_RS14905	COG3023	N-Acetylmuramoyl-L-alanine amidase
CBR69_RS14915	COG0424	maF-like protein
CBR69_RS14920	COG1399	metal-binding, possibly nucleic acid-binding protein
CBR69_RS14925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBR69_RS14935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBR69_RS14945	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS14950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBR69_RS14955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBR69_RS14980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBR69_RS14985	COG0481	GTPase activity
CBR69_RS14990	COG0681	Belongs to the peptidase S26 family
CBR69_RS14995	COG0571	ribonuclease III activity
CBR69_RS15000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBR69_RS15005	COG1381	Involved in DNA repair and RecF pathway recombination
CBR69_RS15025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CBR69_RS15035	COG0583	DNA-binding transcription factor activity
CBR69_RS15050	COG0583	DNA-binding transcription factor activity
CBR69_RS15060	COG0791	NLP P60 protein
CBR69_RS15065	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR69_RS15070	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CBR69_RS15080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR69_RS15085	COG0697	spore germination
CBR69_RS15090	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CBR69_RS15130	COG1446	asparaginase
CBR69_RS15135	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS15140	COG0747	negative chemotaxis
CBR69_RS15145	COG0601	transmembrane transport
CBR69_RS15150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS15170	COG0504	CTP synthase activity
CBR69_RS15180	COG0148	phosphopyruvate hydratase activity
CBR69_RS15195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CBR69_RS15205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR69_RS15210	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR69_RS15230	COG1981	membrane
CBR69_RS15250	COG0039	L-malate dehydrogenase activity
CBR69_RS15255	COG2188	Transcriptional regulator
CBR69_RS15260	COG2009	succinate dehydrogenase
CBR69_RS15265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CBR69_RS15270	COG1053	succinate dehydrogenase
CBR69_RS15275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBR69_RS15280	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CBR69_RS15285	COG0372	Belongs to the citrate synthase family
CBR69_RS15290	COG0583	DNA-binding transcription factor activity
CBR69_RS15295	COG3842	ATPase activity
CBR69_RS15305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBR69_RS15310	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR69_RS15335	COG3128	pkhd-type hydroxylase
CBR69_RS15340	COG4774	siderophore transport
CBR69_RS15345	COG0280	phosphate acetyltransferase
CBR69_RS15345	COG0281	malic enzyme
CBR69_RS15355	COG1297	OPT oligopeptide transporter protein
CBR69_RS15360	COG0567	Dehydrogenase, E1 component
CBR69_RS15365	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR69_RS15370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR69_RS15375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CBR69_RS15400	COG2183	response to ionizing radiation
CBR69_RS15405	COG1199	ATP-dependent helicase activity
CBR69_RS15445	COG0564	pseudouridine synthase activity
CBR69_RS15455	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR69_RS15460	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS15465	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CBR69_RS15480	COG0672	)-iron permease
CBR69_RS15495	COG2823	Periplasmic or secreted lipoprotein
CBR69_RS15505	COG3237	CsbD-like
CBR69_RS15510	COG3038	cytochrome b561
CBR69_RS15515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR69_RS15515	COG0189	ligase activity
CBR69_RS15520	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBR69_RS15520	COG0189	ligase activity
CBR69_RS15525	COG1132	(ABC) transporter
CBR69_RS15535	COG0297	glycogen (starch) synthase activity
CBR69_RS15540	COG2833	Protein of unknown function (DUF455)
CBR69_RS15545	COG2951	lytic endotransglycosylase activity
CBR69_RS15555	COG0589	response to stress
CBR69_RS15565	COG3706	GGDEF domain
CBR69_RS15630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBR69_RS15645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBR69_RS15650	COG0077	Prephenate dehydratase
CBR69_RS15650	COG1605	Chorismate mutase
CBR69_RS15655	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBR69_RS15660	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBR69_RS15665	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CBR69_RS15670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CBR69_RS15690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CBR69_RS15695	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CBR69_RS15700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CBR69_RS15705	COG0587	DNA-directed DNA polymerase activity
CBR69_RS15715	COG2951	lytic endotransglycosylase activity
CBR69_RS15720	COG0123	including yeast histone deacetylase and acetoin utilization protein
CBR69_RS15735	COG2985	domain, Protein
CBR69_RS15740	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS15745	COG0450	alkyl hydroperoxide reductase
CBR69_RS15750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBR69_RS15755	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CBR69_RS15760	COG4208	sulfate ABC transporter
CBR69_RS15765	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBR69_RS15770	COG0175	sulfate reduction
CBR69_RS15780	COG2895	sulfate adenylyltransferase (ATP) activity
CBR69_RS15800	COG0335	large ribosomal subunit rRNA binding
CBR69_RS15805	COG0494	nUDIX hydrolase
CBR69_RS15810	COG3622	Belongs to the hyi family
CBR69_RS15815	COG1162	GTPase activity
CBR69_RS15820	COG0501	Belongs to the peptidase M48B family
CBR69_RS15825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CBR69_RS15830	COG1335	isochorismatase
CBR69_RS15840	COG0583	DNA-binding transcription factor activity
CBR69_RS15855	COG3396	Phenylacetate-CoA oxygenase
CBR69_RS15860	COG3460	Phenylacetate-CoA oxygenase
CBR69_RS15865	COG3396	Phenylacetate-CoA oxygenase
CBR69_RS15870	COG2151	metal-sulfur cluster biosynthetic enzyme
CBR69_RS15875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBR69_RS15880	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS15885	COG1024	Enoyl-CoA hydratase
CBR69_RS15890	COG2050	protein possibly involved in aromatic compounds catabolism
CBR69_RS15910	COG1126	abc transporter atp-binding protein
CBR69_RS15935	COG2198	Histidine kinase
CBR69_RS15935	COG0784	Response regulator, receiver
CBR69_RS15935	COG5002	protein histidine kinase activity
CBR69_RS15940	COG3437	response regulator, receiver
CBR69_RS15955	COG1802	Transcriptional regulator
CBR69_RS15960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR69_RS15960	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR69_RS15970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS15975	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CBR69_RS15985	COG3642	lipopolysaccharide core region biosynthetic process
CBR69_RS15995	COG3842	ATPase activity
CBR69_RS16000	COG1176	ABC-type spermidine putrescine transport system, permease component I
CBR69_RS16005	COG1177	transmembrane transport
CBR69_RS16010	COG1393	Belongs to the ArsC family
CBR69_RS16015	COG2094	Belongs to the DNA glycosylase MPG family
CBR69_RS16025	COG1322	Protein conserved in bacteria
CBR69_RS16030	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS16035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBR69_RS16040	COG0704	Plays a role in the regulation of phosphate uptake
CBR69_RS16045	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CBR69_RS16050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBR69_RS16050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CBR69_RS16055	COG1643	Atp-dependent helicase
CBR69_RS16070	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS16075	COG0726	polysaccharide deacetylase
CBR69_RS16115	COG1132	(ABC) transporter
CBR69_RS16120	COG3468	outer membrane autotransporter barrel domain protein
CBR69_RS16130	COG1530	ribonuclease E activity
CBR69_RS16160	COG0583	DNA-binding transcription factor activity
CBR69_RS16170	COG0477	Major facilitator Superfamily
CBR69_RS16175	COG0500	methyltransferase
CBR69_RS16180	COG1418	mRNA catabolic process
CBR69_RS16205	COG2204	response regulator
CBR69_RS16210	COG4191	Histidine kinase
CBR69_RS16215	COG1301	dicarboxylic acid transport
CBR69_RS16220	COG0424	maF-like protein
CBR69_RS16225	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBR69_RS16230	COG0799	negative regulation of ribosome biogenesis
CBR69_RS16235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CBR69_RS16245	COG0151	Belongs to the GarS family
CBR69_RS16250	COG0217	transcriptional regulatory protein
CBR69_RS16255	COG0433	COG0433 Predicted ATPase
CBR69_RS16260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS16265	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR69_RS16270	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS16295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CBR69_RS16300	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS16305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS16310	COG0601	transmembrane transport
CBR69_RS16315	COG0747	negative chemotaxis
CBR69_RS16325	COG0473	3-isopropylmalate dehydrogenase activity
CBR69_RS16330	COG2814	Major facilitator Superfamily
CBR69_RS16335	COG1566	PFAM secretion protein HlyD family protein
CBR69_RS16345	COG1846	Transcriptional regulator
CBR69_RS16365	COG0501	Belongs to the peptidase M48B family
CBR69_RS16405	COG1722	exodeoxyribonuclease VII activity
CBR69_RS16410	COG0142	geranyltranstransferase activity
CBR69_RS16415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CBR69_RS16420	COG1469	GTP cyclohydrolase I activity
CBR69_RS16425	COG0360	Binds together with S18 to 16S ribosomal RNA
CBR69_RS16430	COG2965	DNA replication, synthesis of RNA primer
CBR69_RS16435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBR69_RS16440	COG0359	binds to the 23S rRNA
CBR69_RS16450	COG0305	Participates in initiation and elongation during chromosome replication
CBR69_RS16460	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CBR69_RS16465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CBR69_RS16470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBR69_RS16475	COG3737	Protein of unknown function (DUF498/DUF598)
CBR69_RS16480	COG0436	Aminotransferase
CBR69_RS16500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CBR69_RS16505	COG0308	aminopeptidase N
CBR69_RS16520	COG0312	modulator of DNA gyrase
CBR69_RS16525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR69_RS16530	COG0277	FAD linked oxidase domain protein
CBR69_RS16535	COG0277	FAD linked oxidase domain protein
CBR69_RS16540	COG0277	FAD linked oxidase domain protein
CBR69_RS16545	COG0247	lactate metabolic process
CBR69_RS16570	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS16575	COG0583	DNA-binding transcription factor activity
CBR69_RS16580	COG0482	sulfurtransferase activity
CBR69_RS16585	COG0730	response to heat
CBR69_RS16590	COG0625	glutathione transferase activity
CBR69_RS16600	COG3909	cytochrome
CBR69_RS16630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CBR69_RS16640	COG3706	GGDEF domain
CBR69_RS16665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBR69_RS16670	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CBR69_RS16680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR69_RS16685	COG0069	glutamate synthase activity
CBR69_RS16690	COG2391	methyltransferase activity
CBR69_RS16695	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CBR69_RS16700	COG0679	Auxin Efflux Carrier
CBR69_RS16730	COG0557	exoribonuclease II activity
CBR69_RS16735	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR69_RS16745	COG0776	regulation of translation
CBR69_RS16775	COG0642	Histidine kinase
CBR69_RS16780	COG3158	transport of potassium into the cell
CBR69_RS16790	COG0137	argininosuccinate synthase activity
CBR69_RS16795	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBR69_RS16800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBR69_RS16810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR69_RS16825	COG2186	Transcriptional regulator
CBR69_RS16845	COG3836	Belongs to the HpcH HpaI aldolase family
CBR69_RS16850	COG0268	Binds directly to 16S ribosomal RNA
CBR69_RS16875	COG0728	peptidoglycan biosynthetic process
CBR69_RS16885	COG0563	adenylate kinase activity
CBR69_RS16890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBR69_RS16895	COG2835	tetraacyldisaccharide 4'-kinase activity
CBR69_RS16900	COG1663	tetraacyldisaccharide 4'-kinase activity
CBR69_RS16910	COG0811	peptide transport
CBR69_RS16915	COG1570	exodeoxyribonuclease VII activity
CBR69_RS16920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBR69_RS16925	COG0038	chloride channel
CBR69_RS16930	COG0183	Belongs to the thiolase family
CBR69_RS16940	COG1278	Cold shock
CBR69_RS16945	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBR69_RS16955	COG4953	penicillin-binding protein 1C
CBR69_RS16960	COG0542	response to heat
CBR69_RS16965	COG2995	paraquat-inducible protein a
CBR69_RS16970	COG3008	intermembrane lipid transfer
CBR69_RS16980	COG0506	proline dehydrogenase activity
CBR69_RS16980	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR69_RS16980	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBR69_RS17010	COG2271	Major facilitator Superfamily
CBR69_RS17020	COG0004	ammonium transporteR
CBR69_RS17025	COG0347	Belongs to the P(II) protein family
CBR69_RS17045	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBR69_RS17050	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBR69_RS17055	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBR69_RS17060	COG0072	phenylalanine-tRNA ligase activity
CBR69_RS17060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR69_RS17065	COG0776	regulation of translation
CBR69_RS17095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CBR69_RS17120	COG1522	sequence-specific DNA binding
CBR69_RS17170	COG5265	(ABC) transporter
CBR69_RS17175	COG0656	L-ascorbic acid biosynthetic process
CBR69_RS17180	COG0667	Aldo Keto reductase
CBR69_RS17195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBR69_RS17220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBR69_RS17240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR69_RS17245	COG3246	L-lysine catabolic process to acetate
CBR69_RS17250	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS17255	COG0583	DNA-binding transcription factor activity
CBR69_RS17265	COG0129	dihydroxy-acid dehydratase activity
CBR69_RS17270	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS17320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS17350	COG2267	carboxylic ester hydrolase activity
CBR69_RS17355	COG0501	Belongs to the peptidase M48B family
CBR69_RS17365	COG0789	Transcriptional regulator
CBR69_RS17370	COG0778	Nitroreductase
CBR69_RS17375	COG0165	Argininosuccinate lyase
CBR69_RS17380	COG0668	transmembrane transport
CBR69_RS17385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CBR69_RS17385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR69_RS17400	COG0583	DNA-binding transcription factor activity
CBR69_RS17410	COG0747	negative chemotaxis
CBR69_RS17415	COG0601	transmembrane transport
CBR69_RS17420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS17425	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS17435	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS17445	COG3161	chorismate lyase activity
CBR69_RS17450	COG1187	pseudouridine synthase activity
CBR69_RS17460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS17485	COG1999	signal sequence binding
CBR69_RS17495	COG0339	signal peptide processing
CBR69_RS17500	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CBR69_RS17505	COG4566	intracellular signal transduction
CBR69_RS17515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CBR69_RS17520	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBR69_RS17525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBR69_RS17535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBR69_RS17535	COG4797	methyltransferase
CBR69_RS17570	COG0745	RESPONSE REGULATOR receiver
CBR69_RS17585	COG0840	transmembrane signaling receptor activity
CBR69_RS17590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CBR69_RS17595	COG2201	protein-glutamate methylesterase activity
CBR69_RS17600	COG0745	RESPONSE REGULATOR receiver
CBR69_RS17605	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CBR69_RS17610	COG0840	transmembrane signaling receptor activity
CBR69_RS17635	COG2747	anti-sigma28 factor FlgM
CBR69_RS17660	COG1749	Flagellar hook protein flgE
CBR69_RS17680	COG1706	bacterial-type flagellum-dependent cell motility
CBR69_RS17690	COG1256	bacterial-type flagellum assembly
CBR69_RS17700	COG0840	transmembrane signaling receptor activity
CBR69_RS17705	COG0840	transmembrane signaling receptor activity
CBR69_RS17715	COG0840	transmembrane signaling receptor activity
CBR69_RS17720	COG0840	transmembrane signaling receptor activity
CBR69_RS17745	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR69_RS17755	COG1580	Controls the rotational direction of flagella during chemotaxis
CBR69_RS17765	COG2882	bacterial-type flagellum organization
CBR69_RS17775	COG1317	bacterial-type flagellum organization
CBR69_RS17780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBR69_RS17785	COG1766	The M ring may be actively involved in energy transduction
CBR69_RS17790	COG1677	Flagellar hook-basal body complex protein FliE
CBR69_RS17800	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBR69_RS17820	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CBR69_RS17840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS17845	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS17855	COG0285	dihydrofolate synthase activity
CBR69_RS17865	COG1286	toxin biosynthetic process
CBR69_RS17885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CBR69_RS17890	COG0024	Methionine aminopeptidase
CBR69_RS17895	COG0052	Belongs to the universal ribosomal protein uS2 family
CBR69_RS17900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBR69_RS17905	COG0528	UMP kinase activity
CBR69_RS17910	COG0233	cytoplasmic translational termination
CBR69_RS17915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBR69_RS17920	COG0575	Belongs to the CDS family
CBR69_RS17925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBR69_RS17930	COG0750	zinc metalloprotease
CBR69_RS17935	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBR69_RS17945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR69_RS17950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CBR69_RS17960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBR69_RS17965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CBR69_RS17970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBR69_RS17980	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBR69_RS18005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBR69_RS18015	COG2914	Belongs to the UPF0125 (RnfH) family
CBR69_RS18020	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS18025	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS18025	COG1024	Enoyl-CoA hydratase
CBR69_RS18045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBR69_RS18050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBR69_RS18060	COG0084	hydrolase, TatD family'
CBR69_RS18075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS18080	COG0765	amino acid transport
CBR69_RS18085	COG1126	abc transporter atp-binding protein
CBR69_RS18090	COG0010	Belongs to the arginase family
CBR69_RS18110	COG4221	oxidoreductase activity
CBR69_RS18115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBR69_RS18125	COG2059	Chromate
CBR69_RS18130	COG0640	Transcriptional regulator
CBR69_RS18140	COG0740	serine-type endopeptidase activity
CBR69_RS18150	COG0095	Lipoate-protein ligase
CBR69_RS18175	COG0386	Belongs to the glutathione peroxidase family
CBR69_RS18200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS18245	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBR69_RS18250	COG2259	Doxx family
CBR69_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS18280	COG0842	Transport permease protein
CBR69_RS18285	COG1129	ABC transporter
CBR69_RS18285	COG0842	Transport permease protein
CBR69_RS18290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBR69_RS18300	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBR69_RS18320	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CBR69_RS18345	COG2733	membrane
CBR69_RS18355	COG3042	response to heat
CBR69_RS18360	COG3258	Cytochrome c
CBR69_RS18390	COG3958	Transketolase
CBR69_RS18395	COG3959	Transketolase, thiamine diphosphate binding domain
CBR69_RS18405	COG1802	Transcriptional regulator
CBR69_RS18455	COG0583	DNA-binding transcription factor activity
CBR69_RS18460	COG0028	Belongs to the TPP enzyme family
CBR69_RS18465	COG0477	Major facilitator Superfamily
CBR69_RS18470	COG0583	DNA-binding transcription factor activity
CBR69_RS18475	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS18480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS18490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBR69_RS18510	COG0519	Catalyzes the synthesis of GMP from XMP
CBR69_RS18510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR69_RS18525	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS18540	COG1024	Enoyl-CoA hydratase
CBR69_RS18555	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS18560	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS18605	COG1122	ATPase activity
CBR69_RS18620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CBR69_RS18625	COG2900	Belongs to the SlyX family
CBR69_RS18640	COG0456	acetyltransferase
CBR69_RS18645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR69_RS18680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBR69_RS18695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBR69_RS18700	COG0714	Associated with various cellular activities
CBR69_RS18720	COG2304	oxidoreductase activity
CBR69_RS18735	COG3119	arylsulfatase activity
CBR69_RS18750	COG3706	GGDEF domain
CBR69_RS18765	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS18795	COG0583	DNA-binding transcription factor activity
CBR69_RS18810	COG1335	isochorismatase
CBR69_RS18825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS18875	COG0066	3-isopropylmalate dehydratase activity
CBR69_RS18880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CBR69_RS18885	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS18890	COG4948	Mandelate Racemase Muconate Lactonizing
CBR69_RS18895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBR69_RS18900	COG3842	ATPase activity
CBR69_RS18905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBR69_RS18915	COG3833	ABC-type maltose transport systems, permease component
CBR69_RS18920	COG1175	transmembrane transport
CBR69_RS18925	COG2182	Extracellular solute-binding protein
CBR69_RS18935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS18940	COG0765	amino acid transport
CBR69_RS18945	COG0765	amino acid transport
CBR69_RS18960	COG3665	Urea carboxylase-associated protein
CBR69_RS18980	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR69_RS19005	COG0583	DNA-binding transcription factor activity
CBR69_RS19020	COG1126	abc transporter atp-binding protein
CBR69_RS19040	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS19050	COG1937	Protein conserved in bacteria
CBR69_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS19095	COG2863	cytochrome
CBR69_RS19100	COG3568	Endonuclease Exonuclease Phosphatase
CBR69_RS19105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBR69_RS19110	COG0392	lysyltransferase activity
CBR69_RS19115	COG0166	Belongs to the GPI family
CBR69_RS19130	COG1546	Belongs to the CinA family
CBR69_RS19130	COG1058	Belongs to the CinA family
CBR69_RS19140	COG0668	transmembrane transport
CBR69_RS19145	COG0297	glycogen (starch) synthase activity
CBR69_RS19155	COG0366	Alpha amylase catalytic
CBR69_RS19160	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR69_RS19170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CBR69_RS19175	COG1640	4-alpha-glucanotransferase
CBR69_RS19205	COG3685	Protein conserved in bacteria
CBR69_RS19210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBR69_RS19215	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS19225	COG1216	Glycosyl transferase, family 2
CBR69_RS19260	COG2192	nodulation
CBR69_RS19270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CBR69_RS19275	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS19280	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS19295	COG5265	(ABC) transporter
CBR69_RS19315	COG0028	Belongs to the TPP enzyme family
CBR69_RS19320	COG2204	response regulator
CBR69_RS19325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBR69_RS19330	COG0583	DNA-binding transcription factor activity
CBR69_RS19335	COG0477	Major facilitator Superfamily
CBR69_RS19340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR69_RS19360	COG1137	ATPase activity
CBR69_RS19385	COG1172	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS19390	COG1129	ABC transporter
CBR69_RS19405	COG2267	carboxylic ester hydrolase activity
CBR69_RS19430	COG0402	S-adenosylhomocysteine deaminase activity
CBR69_RS19435	COG0747	negative chemotaxis
CBR69_RS19440	COG0601	transmembrane transport
CBR69_RS19445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBR69_RS19450	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS19455	COG1063	alcohol dehydrogenase
CBR69_RS19480	COG2175	clavaminate synthase activity
CBR69_RS19485	COG1454	alcohol dehydrogenase
CBR69_RS19490	COG0583	DNA-binding transcription factor activity
CBR69_RS19500	COG1024	Enoyl-CoA hydratase
CBR69_RS19510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS19520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBR69_RS19530	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBR69_RS19530	COG1024	Enoyl-CoA hydratase
CBR69_RS19535	COG0183	Belongs to the thiolase family
CBR69_RS19540	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS19545	COG0318	PFAM AMP-dependent synthetase and ligase
CBR69_RS19550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBR69_RS19565	COG0154	amidase activity
CBR69_RS19570	COG2271	Major facilitator Superfamily
CBR69_RS19580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBR69_RS19610	COG0318	PFAM AMP-dependent synthetase and ligase
CBR69_RS19620	COG2267	carboxylic ester hydrolase activity
CBR69_RS19630	COG1024	Enoyl-CoA hydratase
CBR69_RS19640	COG0431	NADPH-dependent FMN reductase
CBR69_RS19655	COG0683	leucine binding
CBR69_RS19680	COG2819	hydrolase of the alpha beta superfamily
CBR69_RS19695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBR69_RS19705	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR69_RS19735	COG1126	abc transporter atp-binding protein
CBR69_RS19740	COG0765	amino acid transport
CBR69_RS19745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS19770	COG0410	ABC transporter
CBR69_RS19790	COG2200	EAL domain
CBR69_RS19800	COG1595	DNA-templated transcription, initiation
CBR69_RS19815	COG1253	flavin adenine dinucleotide binding
CBR69_RS19825	COG2203	Gaf domain
CBR69_RS19825	COG3706	GGDEF domain
CBR69_RS19825	COG4251	negative regulation of phosphorylation
CBR69_RS19825	COG5001	Diguanylate cyclase
CBR69_RS19830	COG2197	response regulator
CBR69_RS19835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS19835	COG2205	protein histidine kinase activity
CBR69_RS19840	COG2814	Major facilitator Superfamily
CBR69_RS19845	COG0076	glutamate decarboxylase activity
CBR69_RS19850	COG2985	domain, Protein
CBR69_RS19855	COG3189	MarR family transcriptional regulator
CBR69_RS19860	COG2186	Transcriptional regulator
CBR69_RS19865	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS19875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR69_RS19875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR69_RS19885	COG0028	Belongs to the TPP enzyme family
CBR69_RS19895	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS19905	COG0688	phosphatidylethanolamine metabolic process
CBR69_RS19915	COG1464	Belongs to the NlpA lipoprotein family
CBR69_RS19935	COG2363	Small membrane protein
CBR69_RS19940	COG0697	spore germination
CBR69_RS19950	COG2133	pyrroloquinoline quinone binding
CBR69_RS19955	COG0625	glutathione transferase activity
CBR69_RS19965	COG1794	racemase activity, acting on amino acids and derivatives
CBR69_RS19985	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBR69_RS19995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CBR69_RS20010	COG1175	transmembrane transport
CBR69_RS20015	COG0395	ABC-type sugar transport system, permease component
CBR69_RS20020	COG3842	ATPase activity
CBR69_RS20035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBR69_RS20050	COG0438	transferase activity, transferring glycosyl groups
CBR69_RS20070	COG1216	Glycosyl transferase, family 2
CBR69_RS20085	COG0783	Belongs to the Dps family
CBR69_RS20095	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
CBR69_RS20110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBR69_RS20155	COG0583	DNA-binding transcription factor activity
CBR69_RS20160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBR69_RS20180	COG1840	ABC-type Fe3 transport system, periplasmic component
CBR69_RS20190	COG3842	ATPase activity
CBR69_RS20195	COG1741	Belongs to the pirin family
CBR69_RS20200	COG1741	Belongs to the pirin family
CBR69_RS20205	COG0583	DNA-binding transcription factor activity
CBR69_RS20220	COG0784	Response regulator, receiver
CBR69_RS20220	COG2205	protein histidine kinase activity
CBR69_RS20220	COG5002	protein histidine kinase activity
CBR69_RS20235	COG3852	Histidine kinase
CBR69_RS20240	COG0174	glutamine synthetase
CBR69_RS20245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR69_RS20250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBR69_RS20255	COG5001	Diguanylate cyclase
CBR69_RS20255	COG3300	MHYT domain
CBR69_RS20260	COG0840	transmembrane signaling receptor activity
CBR69_RS20270	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS20275	COG2079	MmgE PrpD family protein
CBR69_RS20285	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CBR69_RS20290	COG1561	YicC-like family, N-terminal region
CBR69_RS20305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBR69_RS20310	COG0791	NLP P60 protein
CBR69_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS20320	COG0194	GDP metabolic process
CBR69_RS20325	COG1758	RNA polymerase activity
CBR69_RS20330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBR69_RS20335	COG1126	abc transporter atp-binding protein
CBR69_RS20340	COG0765	amino acid transport
CBR69_RS20345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS20370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS20385	COG2831	hemolysin activation secretion protein
CBR69_RS20395	COG3188	usher protein
CBR69_RS20400	COG3121	Chaperone
CBR69_RS20410	COG3064	Membrane
CBR69_RS20410	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR69_RS20410	COG3210	domain, Protein
CBR69_RS20410	COG3210	domain, Protein
CBR69_RS20410	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
CBR69_RS20410	COG3064	Membrane
CBR69_RS20420	COG4181	ATPase activity
CBR69_RS20430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR69_RS20435	COG0584	glycerophosphoryl diester phosphodiesterase
CBR69_RS20440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CBR69_RS20450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CBR69_RS20450	COG0678	peroxiredoxin activity
CBR69_RS20465	COG0789	Transcriptional regulator
CBR69_RS20470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBR69_RS20495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBR69_RS20505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBR69_RS20525	COG3618	amidohydrolase
CBR69_RS20530	COG0583	DNA-binding transcription factor activity
CBR69_RS20535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBR69_RS20540	COG2252	PERMEase
CBR69_RS20545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBR69_RS20550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBR69_RS20580	COG0583	DNA-binding transcription factor activity
CBR69_RS20585	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBR69_RS20590	COG0488	(ABC) transporter
CBR69_RS20595	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBR69_RS20600	COG0590	tRNA wobble adenosine to inosine editing
CBR69_RS20615	COG1320	monovalent cation:proton antiporter activity
CBR69_RS20620	COG2212	antiporter activity
CBR69_RS20630	COG0651	ATP synthesis coupled electron transport
CBR69_RS20635	COG1006	Multisubunit Na H antiporter MnhC subunit
CBR69_RS20640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CBR69_RS20640	COG2111	Na H antiporter
CBR69_RS20645	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS20655	COG0420	3'-5' exonuclease activity
CBR69_RS20660	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBR69_RS20665	COG1522	sequence-specific DNA binding
CBR69_RS20680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBR69_RS20705	COG2130	NADP-dependent
CBR69_RS20720	COG1131	(ABC) transporter
CBR69_RS20725	COG0842	Transport permease protein
CBR69_RS20735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBR69_RS20770	COG0235	Class ii aldolase
CBR69_RS20775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBR69_RS20780	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS20790	COG1414	Transcriptional regulator
CBR69_RS20795	COG0602	queuosine metabolic process
CBR69_RS20800	COG0720	synthase
CBR69_RS20810	COG1289	transmembrane transporter activity
CBR69_RS20820	COG1566	PFAM secretion protein HlyD family protein
CBR69_RS20830	COG0400	carboxylic ester hydrolase activity
CBR69_RS20835	COG0840	transmembrane signaling receptor activity
CBR69_RS20850	COG0587	DNA-directed DNA polymerase activity
CBR69_RS20860	COG0390	transport system, permease component
CBR69_RS20865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBR69_RS20870	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CBR69_RS20910	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CBR69_RS20920	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS20925	COG1280	lysine exporter protein (LysE YggA)
CBR69_RS20930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBR69_RS20950	COG2764	glyoxalase bleomycin resistance protein dioxygenase
CBR69_RS20975	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS21000	COG0583	DNA-binding transcription factor activity
CBR69_RS21015	COG1522	sequence-specific DNA binding
CBR69_RS21025	COG2814	Major facilitator Superfamily
CBR69_RS21040	COG1396	sequence-specific DNA binding
CBR69_RS21060	COG0183	Belongs to the thiolase family
CBR69_RS21070	COG0583	DNA-binding transcription factor activity
CBR69_RS21075	COG2814	Major facilitator Superfamily
CBR69_RS21080	COG0656	L-ascorbic acid biosynthetic process
CBR69_RS21095	COG2807	transmembrane transport
CBR69_RS21100	COG2207	Transcriptional regulator
CBR69_RS21115	COG1960	acyl-CoA dehydrogenase activity
CBR69_RS21120	COG1024	Enoyl-CoA hydratase
CBR69_RS21135	COG1309	transcriptional regulator
CBR69_RS21150	COG0653	protein targeting
CBR69_RS21185	COG4585	Histidine kinase
CBR69_RS21195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBR69_RS21200	COG1595	DNA-templated transcription, initiation
CBR69_RS21205	COG3712	iron ion homeostasis
CBR69_RS21210	COG4774	siderophore transport
CBR69_RS21215	COG2814	Major facilitator Superfamily
CBR69_RS21220	COG0583	DNA-binding transcription factor activity
CBR69_RS21225	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS21235	COG1349	DNA-binding transcription factor activity
CBR69_RS21245	COG1012	belongs to the aldehyde dehydrogenase family
CBR69_RS21255	COG0411	ABC transporter
CBR69_RS21295	COG0384	phenazine biosynthesis protein PhzF
CBR69_RS21300	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS21320	COG0667	Aldo Keto reductase
CBR69_RS21330	COG0667	Aldo Keto reductase
CBR69_RS21350	COG0667	Aldo Keto reductase
CBR69_RS21425	COG0582	viral genome integration into host DNA
CBR69_RS21430	COG0519	Catalyzes the synthesis of GMP from XMP
CBR69_RS21430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBR69_RS21445	COG1695	Transcriptional regulator
CBR69_RS21460	COG2072	flavoprotein involved in K transport
CBR69_RS21465	COG0601	transmembrane transport
CBR69_RS21475	COG0444	Belongs to the ABC transporter superfamily
CBR69_RS21480	COG4608	Belongs to the ABC transporter superfamily
CBR69_RS21485	COG0747	negative chemotaxis
CBR69_RS21525	COG0047	phosphoribosylformylglycinamidine synthase activity
CBR69_RS21525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBR69_RS21535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR69_RS21540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBR69_RS21540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBR69_RS21545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBR69_RS21555	COG0613	PHP domain protein
CBR69_RS21580	COG2501	S4 domain
CBR69_RS21585	COG0084	hydrolase, TatD family'
CBR69_RS21590	COG1136	(ABC) transporter
CBR69_RS21605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBR69_RS21615	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS21620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CBR69_RS21630	COG1309	transcriptional regulator
CBR69_RS21635	COG1022	Amp-dependent synthetase and ligase
CBR69_RS21665	COG1024	Enoyl-CoA hydratase
CBR69_RS21670	COG1803	Methylglyoxal synthase
CBR69_RS21680	COG2975	iron-sulfur cluster assembly
CBR69_RS21685	COG0633	Ferredoxin
CBR69_RS21690	COG0443	Heat shock 70 kDa protein
CBR69_RS21695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBR69_RS21700	COG0316	Belongs to the HesB IscA family
CBR69_RS21705	COG0822	iron-sulfur transferase activity
CBR69_RS21710	COG1104	cysteine desulfurase activity
CBR69_RS21720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CBR69_RS21725	COG0556	nucleotide-excision repair
CBR69_RS21735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBR69_RS21740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR69_RS21745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBR69_RS21750	COG0740	serine-type endopeptidase activity
CBR69_RS21755	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBR69_RS21765	COG1278	Cold shock
CBR69_RS21775	COG1278	Cold shock
CBR69_RS21800	COG3468	outer membrane autotransporter barrel domain protein
CBR69_RS21825	COG2171	N-acyltransferase activity
CBR69_RS21830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBR69_RS21835	COG2890	protein-(glutamine-N5) methyltransferase activity
CBR69_RS21840	COG0488	(ABC) transporter
CBR69_RS21845	COG0210	DNA helicase
CBR69_RS21860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBR69_RS21860	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBR69_RS21865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBR69_RS21870	COG0196	riboflavin kinase activity
CBR69_RS21875	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CBR69_RS21880	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBR69_RS21885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBR69_RS21895	COG1522	sequence-specific DNA binding
CBR69_RS21910	COG0586	Pfam SNARE associated Golgi protein
CBR69_RS21920	COG0756	dUTP diphosphatase activity
CBR69_RS21925	COG1902	pentaerythritol trinitrate reductase activity
CBR69_RS21930	COG1126	abc transporter atp-binding protein
CBR69_RS21935	COG0765	amino acid transport
CBR69_RS21940	COG0765	amino acid transport
CBR69_RS21945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBR69_RS21955	COG2423	ornithine cyclodeaminase activity
CBR69_RS21960	COG1764	response to oxidative stress
CBR69_RS21965	COG1914	H( )-stimulated, divalent metal cation uptake system
CBR69_RS21970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBR69_RS21975	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBR69_RS21990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBR69_RS21995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBR69_RS22000	COG2197	response regulator
CBR69_RS22005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBR69_RS22025	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS22030	COG0840	transmembrane signaling receptor activity
CBR69_RS22190	COG5410	chromosome segregation
CBR69_RS22315	COG0419	ATPase involved in DNA repair
CBR69_RS22345	COG0582	viral genome integration into host DNA
CBR69_RS22355	COG0135	phosphoribosylanthranilate isomerase activity
CBR69_RS22360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBR69_RS22365	COG0101	tRNA pseudouridine synthase activity
CBR69_RS22375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CBR69_RS22380	COG0473	3-isopropylmalate dehydrogenase activity
CBR69_RS22385	COG0066	3-isopropylmalate dehydratase activity
CBR69_RS22395	COG2197	response regulator
CBR69_RS22410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBR69_RS22420	COG2205	protein histidine kinase activity
CBR69_RS22430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBR69_RS22440	COG1295	ribonuclease BN
CBR69_RS22450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBR69_RS22480	COG1450	Type ii and iii secretion system protein
CBR69_RS22515	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBR69_RS22555	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS22570	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS22600	COG0181	hydroxymethylbilane synthase activity
CBR69_RS22605	COG0861	Integral membrane protein TerC family
CBR69_RS22610	COG0861	Integral membrane protein TerC family
CBR69_RS22615	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CBR69_RS22620	COG0045	succinate-CoA ligase (ADP-forming) activity
CBR69_RS22630	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBR69_RS22640	COG2137	regulation of response to DNA damage stimulus
CBR69_RS22645	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBR69_RS22670	COG2974	May be involved in recombination
CBR69_RS22675	COG0540	Belongs to the ATCase OTCase family
CBR69_RS22705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBR69_RS22735	COG0500	methyltransferase
CBR69_RS22740	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS22755	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CBR69_RS22760	COG0747	negative chemotaxis
CBR69_RS22780	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBR69_RS22805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBR69_RS22835	COG0811	peptide transport
CBR69_RS22870	COG2188	Transcriptional regulator
CBR69_RS22875	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS22890	COG0583	DNA-binding transcription factor activity
CBR69_RS22900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBR69_RS22910	COG4172	Belongs to the ABC transporter superfamily
CBR69_RS22920	COG0601	transmembrane transport
CBR69_RS22925	COG4166	transmembrane transport
CBR69_RS22930	COG2267	carboxylic ester hydrolase activity
CBR69_RS22935	COG4638	Rieske (2fe-2S)
CBR69_RS22945	COG0583	DNA-binding transcription factor activity
CBR69_RS22950	COG2146	nitrite reductase [NAD(P)H] activity
CBR69_RS22955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBR69_RS22960	COG1595	DNA-templated transcription, initiation
CBR69_RS22965	COG3712	iron ion homeostasis
CBR69_RS22970	COG4774	siderophore transport
CBR69_RS22995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CBR69_RS23005	COG3246	L-lysine catabolic process to acetate
CBR69_RS23010	COG3181	Tripartite tricarboxylate transporter family receptor
CBR69_RS23025	COG1028	Short-chain dehydrogenase reductase Sdr
CBR69_RS23030	COG0583	DNA-binding transcription factor activity
CBR69_RS23060	COG0457	Tetratricopeptide repeat
CBR69_RS23065	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CBR69_RS23070	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS23075	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS23080	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS23105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBR69_RS23145	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBR69_RS23160	COG1215	transferase activity, transferring glycosyl groups
CBR69_RS23170	COG3307	-O-antigen