locus-tag	class	description
FYA37_RS00005	COG0445	tRNA wobble uridine modification
FYA37_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
FYA37_RS00015	COG1192	Involved in chromosome partitioning
FYA37_RS00020	COG1475	DNA binding
FYA37_RS00025	COG0252	asparaginase activity
FYA37_RS00045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA37_RS00055	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FYA37_RS00065	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FYA37_RS00070	COG0081	regulation of translation
FYA37_RS00075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FYA37_RS00080	COG0222	ribosome binding
FYA37_RS00085	COG0085	RNA polymerase activity
FYA37_RS00090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FYA37_RS00125	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FYA37_RS00130	COG0049	tRNA binding
FYA37_RS00135	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA37_RS00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FYA37_RS00145	COG0051	transcription antitermination factor activity, RNA binding
FYA37_RS00150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FYA37_RS00155	COG0088	Forms part of the polypeptide exit tunnel
FYA37_RS00160	COG0089	rRNA binding
FYA37_RS00165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FYA37_RS00170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FYA37_RS00175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FYA37_RS00180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FYA37_RS00185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FYA37_RS00190	COG0255	Belongs to the universal ribosomal protein uL29 family
FYA37_RS00195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FYA37_RS00205	COG4177	L-phenylalanine transmembrane transporter activity
FYA37_RS00215	COG1129	ABC transporter
FYA37_RS00220	COG0411	ABC transporter
FYA37_RS00250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FYA37_RS00255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FYA37_RS00260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FYA37_RS00265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FYA37_RS00270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FYA37_RS00275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FYA37_RS00280	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FYA37_RS00285	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FYA37_RS00290	COG1841	ribosomal large subunit assembly
FYA37_RS00295	COG0200	Binds to the 23S rRNA
FYA37_RS00300	COG0201	protein transport
FYA37_RS00305	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA37_RS00310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA37_RS00315	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FYA37_RS00320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FYA37_RS00325	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FYA37_RS00330	COG0202	RNA polymerase activity
FYA37_RS00335	COG0203	ribosomal protein L17
FYA37_RS00340	COG0537	adenosine 5'-monophosphoramidase activity
FYA37_RS00345	COG1324	tolerance protein
FYA37_RS00350	COG4232	protein-disulfide reductase activity
FYA37_RS00365	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FYA37_RS00375	COG1333	cytochrome c biogenesis protein
FYA37_RS00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FYA37_RS00395	COG1965	Belongs to the frataxin family
FYA37_RS00405	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA37_RS00410	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FYA37_RS00415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FYA37_RS00435	COG2814	Major facilitator Superfamily
FYA37_RS00460	COG2801	Transposase and inactivated derivatives
FYA37_RS00490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA37_RS00495	COG2922	Belongs to the Smg family
FYA37_RS00500	COG1629	transport
FYA37_RS00510	COG2358	TRAP transporter, solute receptor (TAXI family
FYA37_RS00520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA37_RS00535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA37_RS00540	COG0183	Belongs to the thiolase family
FYA37_RS00545	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS00570	COG2200	EAL domain
FYA37_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA37_RS00585	COG0018	arginyl-trna synthetase
FYA37_RS00600	COG0154	amidase activity
FYA37_RS00605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA37_RS00615	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FYA37_RS00625	COG0697	spore germination
FYA37_RS00695	COG3350	monooxygenase activity
FYA37_RS00720	COG1309	transcriptional regulator
FYA37_RS00750	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA37_RS00755	COG1280	lysine exporter protein (LysE YggA)
FYA37_RS00760	COG0513	Belongs to the DEAD box helicase family
FYA37_RS00770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYA37_RS00775	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA37_RS00805	COG2969	positive regulation of protein catabolic process
FYA37_RS00810	COG0625	glutathione transferase activity
FYA37_RS00815	COG2857	Cytochrome c1
FYA37_RS00820	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FYA37_RS00825	COG0723	plastoquinol--plastocyanin reductase activity
FYA37_RS00830	COG1970	mechanosensitive ion channel activity
FYA37_RS00835	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA37_RS00840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA37_RS00850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA37_RS00855	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FYA37_RS00865	COG0140	phosphoribosyl-ATP diphosphatase activity
FYA37_RS00870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA37_RS00875	COG0107	imidazoleglycerol-phosphate synthase activity
FYA37_RS00880	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FYA37_RS00890	COG0131	Imidazoleglycerol-phosphate dehydratase
FYA37_RS00895	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA37_RS00900	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA37_RS00905	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA37_RS00910	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA37_RS00915	COG0271	Belongs to the BolA IbaG family
FYA37_RS00920	COG0842	Transport permease protein
FYA37_RS00925	COG1131	(ABC) transporter
FYA37_RS00940	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA37_RS00945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA37_RS00950	COG1127	ABC transporter
FYA37_RS00970	COG0070	glutamate synthase
FYA37_RS00970	COG0069	glutamate synthase activity
FYA37_RS00970	COG0067	glutamate synthase
FYA37_RS00995	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FYA37_RS01015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FYA37_RS01020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA37_RS01065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA37_RS01100	COG0109	protoheme IX farnesyltransferase activity
FYA37_RS01105	COG1999	signal sequence binding
FYA37_RS01125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FYA37_RS01130	COG2814	Major facilitator Superfamily
FYA37_RS01145	COG1522	sequence-specific DNA binding
FYA37_RS01210	COG4948	Mandelate Racemase Muconate Lactonizing
FYA37_RS01225	COG3119	arylsulfatase activity
FYA37_RS01260	COG0402	S-adenosylhomocysteine deaminase activity
FYA37_RS01270	COG1304	FMN binding
FYA37_RS01275	COG1254	Belongs to the acylphosphatase family
FYA37_RS01285	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS01295	COG1414	Transcriptional regulator
FYA37_RS01315	COG0028	Belongs to the TPP enzyme family
FYA37_RS01320	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
FYA37_RS01325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS01330	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS01365	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS01370	COG0583	DNA-binding transcription factor activity
FYA37_RS01385	COG0129	dihydroxy-acid dehydratase activity
FYA37_RS01390	COG2084	Dehydrogenase
FYA37_RS01405	COG1671	Belongs to the UPF0178 family
FYA37_RS01410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA37_RS01420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FYA37_RS01425	COG0443	Heat shock 70 kDa protein
FYA37_RS01450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA37_RS01450	COG2169	Transcriptional regulator
FYA37_RS01465	COG1683	Conserved Protein
FYA37_RS01470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA37_RS01485	COG1120	ATPase activity
FYA37_RS01490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA37_RS01495	COG4558	Periplasmic binding protein
FYA37_RS01500	COG3720	iron ion transport
FYA37_RS01510	COG3712	iron ion homeostasis
FYA37_RS01515	COG1595	DNA-templated transcription, initiation
FYA37_RS01535	COG1607	acyl-coa hydrolase
FYA37_RS01550	COG0437	4 iron, 4 sulfur cluster binding
FYA37_RS01555	COG2864	formate dehydrogenase
FYA37_RS01570	COG3276	selenocysteine insertion sequence binding
FYA37_RS01605	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA37_RS01610	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA37_RS01620	COG0546	phosphoglycolate phosphatase activity
FYA37_RS01625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA37_RS01630	COG2967	ApaG domain
FYA37_RS01635	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FYA37_RS01640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA37_RS01645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA37_RS01650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA37_RS01655	COG0037	tRNA processing
FYA37_RS01675	COG1024	Enoyl-CoA hydratase
FYA37_RS01690	COG0356	it plays a direct role in the translocation of protons across the membrane
FYA37_RS01700	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FYA37_RS01705	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FYA37_RS01710	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FYA37_RS01715	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FYA37_RS01720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FYA37_RS01725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FYA37_RS01745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FYA37_RS01750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA37_RS01755	COG0210	DNA helicase
FYA37_RS01770	COG4608	Belongs to the ABC transporter superfamily
FYA37_RS01775	COG0444	Belongs to the ABC transporter superfamily
FYA37_RS01780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS01805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA37_RS01810	COG1024	Enoyl-CoA hydratase
FYA37_RS01815	COG1024	Enoyl-CoA hydratase
FYA37_RS01820	COG2070	2-Nitropropane dioxygenase
FYA37_RS01835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS01840	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA37_RS01860	COG2267	carboxylic ester hydrolase activity
FYA37_RS01880	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA37_RS01890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA37_RS01890	COG2813	Specifically methylates the guanine in position
FYA37_RS01895	COG2223	nitrite transmembrane transporter activity
FYA37_RS01900	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA37_RS01915	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA37_RS01920	COG0708	Exodeoxyribonuclease III
FYA37_RS01925	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FYA37_RS01930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA37_RS01935	COG0154	amidase activity
FYA37_RS01940	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA37_RS01945	COG1077	Cell shape determining protein MreB Mrl
FYA37_RS01950	COG1792	Involved in formation and maintenance of cell shape
FYA37_RS01960	COG0768	penicillin binding
FYA37_RS01965	COG0772	Belongs to the SEDS family
FYA37_RS01970	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FYA37_RS01975	COG0471	metal ion transport
FYA37_RS01980	COG1309	transcriptional regulator
FYA37_RS01990	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA37_RS02005	COG2823	Periplasmic or secreted lipoprotein
FYA37_RS02010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FYA37_RS02015	COG0792	nuclease activity
FYA37_RS02035	COG1660	Displays ATPase and GTPase activities
FYA37_RS02050	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FYA37_RS02060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FYA37_RS02070	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS02075	COG1473	amidohydrolase
FYA37_RS02080	COG1137	ATPase activity
FYA37_RS02095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA37_RS02105	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FYA37_RS02125	COG1294	oxidase, subunit
FYA37_RS02135	COG4988	ABC transporter
FYA37_RS02140	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FYA37_RS02145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FYA37_RS02160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA37_RS02165	COG1238	metal cluster binding
FYA37_RS02175	COG1802	Transcriptional regulator
FYA37_RS02185	COG1984	allophanate hydrolase subunit 2
FYA37_RS02190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FYA37_RS02200	COG0583	DNA-binding transcription factor activity
FYA37_RS02205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA37_RS02210	COG5002	protein histidine kinase activity
FYA37_RS02215	COG0745	RESPONSE REGULATOR receiver
FYA37_RS02220	COG2226	methyltransferase
FYA37_RS02265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA37_RS02275	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS02295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA37_RS02300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA37_RS02310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA37_RS02330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FYA37_RS02335	COG1538	Outer membrane efflux protein
FYA37_RS02345	COG0351	phosphomethylpyrimidine kinase
FYA37_RS02350	COG2022	thiamine diphosphate biosynthetic process
FYA37_RS02355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FYA37_RS02375	COG2226	methyltransferase
FYA37_RS02385	COG1194	a g-specific adenine glycosylase
FYA37_RS02395	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FYA37_RS02400	COG2177	Part of the ABC transporter FtsEX involved in
FYA37_RS02405	COG2884	Cell division ATP-binding protein ftsE
FYA37_RS02410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS02415	COG4597	amino acid ABC transporter
FYA37_RS02420	COG0765	amino acid transport
FYA37_RS02425	COG1126	abc transporter atp-binding protein
FYA37_RS02455	COG0477	Major facilitator Superfamily
FYA37_RS02465	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA37_RS02470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FYA37_RS02485	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FYA37_RS02490	COG0237	dephospho-CoA kinase activity
FYA37_RS02495	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FYA37_RS02505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA37_RS02520	COG3539	Fimbrial protein
FYA37_RS02525	COG3539	Fimbrial protein
FYA37_RS02540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA37_RS02550	COG1846	Transcriptional regulator
FYA37_RS02620	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS02625	COG1024	Enoyl-CoA hydratase
FYA37_RS02630	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS02660	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FYA37_RS02665	COG0352	thiamine-phosphate diphosphorylase activity
FYA37_RS02670	COG0351	phosphomethylpyrimidine kinase
FYA37_RS02680	COG1678	Uncharacterized ACR, COG1678
FYA37_RS02685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA37_RS02710	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA37_RS02720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA37_RS02725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FYA37_RS02735	COG0557	exoribonuclease II activity
FYA37_RS02745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA37_RS02750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA37_RS02755	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FYA37_RS02765	COG0439	Biotin carboxylase
FYA37_RS02770	COG2264	protein methyltransferase activity
FYA37_RS02780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA37_RS02805	COG1696	Membrane protein involved in D-alanine export
FYA37_RS02810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA37_RS02855	COG1522	sequence-specific DNA binding
FYA37_RS02870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA37_RS02935	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FYA37_RS02960	COG3028	Belongs to the UPF0307 family
FYA37_RS02965	COG0312	modulator of DNA gyrase
FYA37_RS02970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FYA37_RS02975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA37_RS02980	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA37_RS02990	COG0316	Belongs to the HesB IscA family
FYA37_RS03000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYA37_RS03010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA37_RS03015	COG1881	PFAM PEBP family protein
FYA37_RS03020	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FYA37_RS03025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FYA37_RS03040	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA37_RS03040	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA37_RS03055	COG2718	Belongs to the UPF0229 family
FYA37_RS03060	COG2719	SpoVR family
FYA37_RS03120	COG0165	Argininosuccinate lyase
FYA37_RS03125	COG0589	response to stress
FYA37_RS03135	COG2816	NAD+ diphosphatase activity
FYA37_RS03140	COG4993	Dehydrogenase
FYA37_RS03165	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS03170	COG2979	Protein of unknown function (DUF533)
FYA37_RS03175	COG4206	TonB-dependent receptor
FYA37_RS03190	COG0741	lytic transglycosylase activity
FYA37_RS03190	COG1388	LysM domain
FYA37_RS03195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA37_RS03200	COG2226	methyltransferase
FYA37_RS03205	COG0328	RNA-DNA hybrid ribonuclease activity
FYA37_RS03230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA37_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS03255	COG0842	Transport permease protein
FYA37_RS03255	COG1129	ABC transporter
FYA37_RS03260	COG0842	Transport permease protein
FYA37_RS03280	COG0463	Glycosyl transferase, family 2
FYA37_RS03285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FYA37_RS03300	COG1073	alpha beta
FYA37_RS03310	COG0697	spore germination
FYA37_RS03315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA37_RS03340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FYA37_RS03370	COG0823	Involved in the tonB-independent uptake of proteins
FYA37_RS03380	COG0848	biopolymer transport protein
FYA37_RS03385	COG0811	peptide transport
FYA37_RS03390	COG0824	Thioesterase
FYA37_RS03395	COG0442	prolyl-tRNA aminoacylation
FYA37_RS03440	COG2084	Dehydrogenase
FYA37_RS03485	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FYA37_RS03490	COG4654	Cytochrome c, class I
FYA37_RS03495	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA37_RS03560	COG1473	amidohydrolase
FYA37_RS03565	COG0418	dihydroorotase activity
FYA37_RS03570	COG0488	(ABC) transporter
FYA37_RS03580	COG2001	Belongs to the MraZ family
FYA37_RS03585	COG0275	rRNA processing
FYA37_RS03590	COG3116	cell division
FYA37_RS03600	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYA37_RS03605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA37_RS03610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FYA37_RS03620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FYA37_RS03625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA37_RS03630	COG1181	Belongs to the D-alanine--D-alanine ligase family
FYA37_RS03635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA37_RS03650	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FYA37_RS03665	COG0739	heme binding
FYA37_RS03670	COG0653	protein targeting
FYA37_RS03695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FYA37_RS03700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA37_RS03710	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FYA37_RS03760	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FYA37_RS03775	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
FYA37_RS03800	COG0583	DNA-binding transcription factor activity
FYA37_RS03810	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS03815	COG2084	Dehydrogenase
FYA37_RS03825	COG1597	lipid kinase activity
FYA37_RS03825	COG1803	Methylglyoxal synthase
FYA37_RS03835	COG0671	phosphoesterase, PA-phosphatase related
FYA37_RS03855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA37_RS03860	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA37_RS03865	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA37_RS03870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA37_RS03875	COG0649	NAD binding
FYA37_RS03880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FYA37_RS03890	COG1034	ATP synthesis coupled electron transport
FYA37_RS03895	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FYA37_RS03900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA37_RS03910	COG0713	ATP synthesis coupled electron transport
FYA37_RS03925	COG1007	ATP synthesis coupled electron transport
FYA37_RS03935	COG0560	Phosphoserine phosphatase
FYA37_RS03940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA37_RS03945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FYA37_RS03950	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FYA37_RS03965	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA37_RS03970	COG0450	alkyl hydroperoxide reductase
FYA37_RS03990	COG1214	PFAM Peptidase M22, glycoprotease
FYA37_RS03995	COG1573	uracil-dna glycosylase
FYA37_RS04000	COG0477	Major facilitator Superfamily
FYA37_RS04005	COG1196	nuclear chromosome segregation
FYA37_RS04015	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FYA37_RS04020	COG1126	abc transporter atp-binding protein
FYA37_RS04025	COG0765	amino acid transport
FYA37_RS04030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS04035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA37_RS04040	COG2917	probably involved in intracellular septation
FYA37_RS04045	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FYA37_RS04050	COG1122	ATPase activity
FYA37_RS04055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FYA37_RS04090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA37_RS04120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA37_RS04125	COG2878	Part of a membrane complex involved in electron transport
FYA37_RS04145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FYA37_RS04150	COG0251	oxidation-reduction process
FYA37_RS04160	COG3228	Belongs to the MtfA family
FYA37_RS04165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA37_RS04175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA37_RS04185	COG0159	tryptophan synthase activity
FYA37_RS04190	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FYA37_RS04195	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYA37_RS04210	COG1530	ribonuclease E activity
FYA37_RS04215	COG0564	pseudouridine synthase activity
FYA37_RS04220	COG0546	phosphoglycolate phosphatase activity
FYA37_RS04225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FYA37_RS04230	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FYA37_RS04235	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA37_RS04245	COG0424	maF-like protein
FYA37_RS04255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FYA37_RS04265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FYA37_RS04275	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS04280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FYA37_RS04285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FYA37_RS04310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA37_RS04345	COG0481	GTPase activity
FYA37_RS04350	COG0681	Belongs to the peptidase S26 family
FYA37_RS04355	COG0571	ribonuclease III activity
FYA37_RS04360	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA37_RS04365	COG1381	Involved in DNA repair and RecF pathway recombination
FYA37_RS04385	COG0670	Belongs to the BI1 family
FYA37_RS04400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FYA37_RS04425	COG0583	DNA-binding transcription factor activity
FYA37_RS04440	COG0791	NLP P60 protein
FYA37_RS04445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA37_RS04450	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FYA37_RS04460	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA37_RS04480	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FYA37_RS04515	COG1446	asparaginase
FYA37_RS04520	COG4172	Belongs to the ABC transporter superfamily
FYA37_RS04525	COG0747	negative chemotaxis
FYA37_RS04530	COG0601	transmembrane transport
FYA37_RS04555	COG0504	CTP synthase activity
FYA37_RS04565	COG0148	phosphopyruvate hydratase activity
FYA37_RS04580	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FYA37_RS04590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA37_RS04595	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA37_RS04635	COG1981	membrane
FYA37_RS04655	COG0039	L-malate dehydrogenase activity
FYA37_RS04660	COG2188	Transcriptional regulator
FYA37_RS04665	COG2009	succinate dehydrogenase
FYA37_RS04670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA37_RS04675	COG1053	succinate dehydrogenase
FYA37_RS04680	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA37_RS04685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA37_RS04690	COG0372	Belongs to the citrate synthase family
FYA37_RS04700	COG0583	DNA-binding transcription factor activity
FYA37_RS04705	COG3842	ATPase activity
FYA37_RS04715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA37_RS04720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA37_RS04730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA37_RS04740	COG3128	pkhd-type hydroxylase
FYA37_RS04745	COG4774	siderophore transport
FYA37_RS04755	COG0280	phosphate acetyltransferase
FYA37_RS04755	COG0281	malic enzyme
FYA37_RS04765	COG1297	OPT oligopeptide transporter protein
FYA37_RS04770	COG0567	Dehydrogenase, E1 component
FYA37_RS04775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA37_RS04780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA37_RS04785	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA37_RS04790	COG1595	DNA-templated transcription, initiation
FYA37_RS04800	COG4774	siderophore transport
FYA37_RS04825	COG2183	response to ionizing radiation
FYA37_RS04830	COG1199	ATP-dependent helicase activity
FYA37_RS04840	COG0564	pseudouridine synthase activity
FYA37_RS04850	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA37_RS04855	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS04860	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FYA37_RS04875	COG0672	)-iron permease
FYA37_RS04890	COG2823	Periplasmic or secreted lipoprotein
FYA37_RS04910	COG3237	CsbD-like
FYA37_RS04915	COG3038	cytochrome b561
FYA37_RS04930	COG1132	(ABC) transporter
FYA37_RS04945	COG2833	Protein of unknown function (DUF455)
FYA37_RS04950	COG2951	lytic endotransglycosylase activity
FYA37_RS04975	COG0586	Pfam SNARE associated Golgi protein
FYA37_RS05030	COG0165	Argininosuccinate lyase
FYA37_RS05050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FYA37_RS05065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FYA37_RS05070	COG1605	Chorismate mutase
FYA37_RS05070	COG0077	Prephenate dehydratase
FYA37_RS05075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FYA37_RS05085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYA37_RS05090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FYA37_RS05110	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FYA37_RS05115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FYA37_RS05120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA37_RS05125	COG0587	DNA-directed DNA polymerase activity
FYA37_RS05135	COG2951	lytic endotransglycosylase activity
FYA37_RS05140	COG0123	including yeast histone deacetylase and acetoin utilization protein
FYA37_RS05155	COG2985	domain, Protein
FYA37_RS05160	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS05165	COG0450	alkyl hydroperoxide reductase
FYA37_RS05170	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA37_RS05175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA37_RS05180	COG4208	sulfate ABC transporter
FYA37_RS05185	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA37_RS05190	COG0175	sulfate reduction
FYA37_RS05220	COG0335	large ribosomal subunit rRNA binding
FYA37_RS05235	COG3622	Belongs to the hyi family
FYA37_RS05240	COG1162	GTPase activity
FYA37_RS05245	COG0501	Belongs to the peptidase M48B family
FYA37_RS05250	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA37_RS05255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA37_RS05260	COG3327	negative regulation of DNA-templated transcription, initiation
FYA37_RS05265	COG3396	Phenylacetate-CoA oxygenase
FYA37_RS05270	COG3460	Phenylacetate-CoA oxygenase
FYA37_RS05275	COG3396	Phenylacetate-CoA oxygenase
FYA37_RS05280	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA37_RS05285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA37_RS05290	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS05295	COG1024	Enoyl-CoA hydratase
FYA37_RS05300	COG2050	protein possibly involved in aromatic compounds catabolism
FYA37_RS05330	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA37_RS05330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA37_RS05340	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA37_RS05345	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA37_RS05350	COG2346	COG2346, Truncated hemoglobins
FYA37_RS05355	COG3642	lipopolysaccharide core region biosynthetic process
FYA37_RS05365	COG3842	ATPase activity
FYA37_RS05370	COG1176	ABC-type spermidine putrescine transport system, permease component I
FYA37_RS05375	COG1177	transmembrane transport
FYA37_RS05395	COG1322	Protein conserved in bacteria
FYA37_RS05405	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FYA37_RS05410	COG0704	Plays a role in the regulation of phosphate uptake
FYA37_RS05415	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FYA37_RS05420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FYA37_RS05420	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FYA37_RS05425	COG1643	Atp-dependent helicase
FYA37_RS05440	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS05445	COG0726	polysaccharide deacetylase
FYA37_RS05450	COG0463	Glycosyl transferase, family 2
FYA37_RS05485	COG1132	(ABC) transporter
FYA37_RS05505	COG0501	Belongs to the peptidase M48B family
FYA37_RS05550	COG1722	exodeoxyribonuclease VII activity
FYA37_RS05555	COG0142	geranyltranstransferase activity
FYA37_RS05560	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FYA37_RS05565	COG1469	GTP cyclohydrolase I activity
FYA37_RS05570	COG0360	Binds together with S18 to 16S ribosomal RNA
FYA37_RS05575	COG2965	DNA replication, synthesis of RNA primer
FYA37_RS05580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FYA37_RS05585	COG0359	binds to the 23S rRNA
FYA37_RS05595	COG0305	Participates in initiation and elongation during chromosome replication
FYA37_RS05605	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA37_RS05610	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FYA37_RS05615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA37_RS05620	COG3737	Protein of unknown function (DUF498/DUF598)
FYA37_RS05625	COG0436	Aminotransferase
FYA37_RS05650	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FYA37_RS05655	COG0308	aminopeptidase N
FYA37_RS05670	COG0312	modulator of DNA gyrase
FYA37_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA37_RS05695	COG0277	FAD linked oxidase domain protein
FYA37_RS05700	COG0277	FAD linked oxidase domain protein
FYA37_RS05705	COG0247	lactate metabolic process
FYA37_RS05745	COG0583	DNA-binding transcription factor activity
FYA37_RS05750	COG0482	sulfurtransferase activity
FYA37_RS05755	COG0730	response to heat
FYA37_RS05760	COG0625	glutathione transferase activity
FYA37_RS05765	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYA37_RS05770	COG3909	cytochrome
FYA37_RS05805	COG3706	GGDEF domain
FYA37_RS05820	COG2826	transposase and inactivated derivatives, IS30 family
FYA37_RS05840	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FYA37_RS05865	COG0069	glutamate synthase activity
FYA37_RS05875	COG2391	methyltransferase activity
FYA37_RS05880	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FYA37_RS05885	COG0679	Auxin Efflux Carrier
FYA37_RS05890	COG2153	protein acetylation
FYA37_RS05910	COG0557	exoribonuclease II activity
FYA37_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA37_RS05920	COG2873	o-acetylhomoserine
FYA37_RS05925	COG0776	regulation of translation
FYA37_RS05955	COG0642	Histidine kinase
FYA37_RS05960	COG3158	transport of potassium into the cell
FYA37_RS05985	COG0137	argininosuccinate synthase activity
FYA37_RS05990	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FYA37_RS05995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA37_RS06005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA37_RS06020	COG2186	Transcriptional regulator
FYA37_RS06050	COG3836	Belongs to the HpcH HpaI aldolase family
FYA37_RS06055	COG0268	Binds directly to 16S ribosomal RNA
FYA37_RS06100	COG0728	peptidoglycan biosynthetic process
FYA37_RS06110	COG0563	adenylate kinase activity
FYA37_RS06115	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FYA37_RS06120	COG2835	tetraacyldisaccharide 4'-kinase activity
FYA37_RS06125	COG1663	tetraacyldisaccharide 4'-kinase activity
FYA37_RS06130	COG0848	biopolymer transport protein
FYA37_RS06135	COG0811	peptide transport
FYA37_RS06140	COG1570	exodeoxyribonuclease VII activity
FYA37_RS06145	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA37_RS06155	COG0038	chloride channel
FYA37_RS06160	COG0183	Belongs to the thiolase family
FYA37_RS06170	COG1278	Cold shock
FYA37_RS06175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA37_RS06185	COG4953	penicillin-binding protein 1C
FYA37_RS06200	COG3008	intermembrane lipid transfer
FYA37_RS06210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA37_RS06210	COG0506	proline dehydrogenase activity
FYA37_RS06210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA37_RS06240	COG0004	ammonium transporteR
FYA37_RS06245	COG0347	Belongs to the P(II) protein family
FYA37_RS06295	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FYA37_RS06300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FYA37_RS06305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FYA37_RS06310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA37_RS06310	COG0072	phenylalanine-tRNA ligase activity
FYA37_RS06315	COG0776	regulation of translation
FYA37_RS06345	COG1802	Transcriptional regulator
FYA37_RS06350	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS06370	COG1278	Cold shock
FYA37_RS06380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA37_RS06400	COG1522	sequence-specific DNA binding
FYA37_RS06450	COG5265	(ABC) transporter
FYA37_RS06470	COG0656	L-ascorbic acid biosynthetic process
FYA37_RS06475	COG0667	Aldo Keto reductase
FYA37_RS06490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA37_RS06535	COG1610	YqeY-like protein
FYA37_RS06550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA37_RS06555	COG3246	L-lysine catabolic process to acetate
FYA37_RS06575	COG0318	PFAM AMP-dependent synthetase and ligase
FYA37_RS06590	COG0183	Belongs to the thiolase family
FYA37_RS06595	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA37_RS06595	COG1024	Enoyl-CoA hydratase
FYA37_RS06605	COG1024	Enoyl-CoA hydratase
FYA37_RS06605	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA37_RS06610	COG0183	Belongs to the thiolase family
FYA37_RS06615	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS06625	COG1045	serine acetyltransferase
FYA37_RS06635	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA37_RS06640	COG0483	inositol monophosphate 1-phosphatase activity
FYA37_RS06645	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS06650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA37_RS06665	COG0210	DNA helicase
FYA37_RS06670	COG0598	Magnesium transport protein CorA
FYA37_RS06680	COG0747	negative chemotaxis
FYA37_RS06685	COG0601	transmembrane transport
FYA37_RS06690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS06695	COG4172	Belongs to the ABC transporter superfamily
FYA37_RS06715	COG1346	cytolysis
FYA37_RS06725	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS06730	COG0783	Belongs to the Dps family
FYA37_RS06750	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
FYA37_RS06760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA37_RS06765	COG1845	cytochrome c oxidase, subunit III
FYA37_RS06770	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA37_RS06815	COG1666	GTP binding
FYA37_RS06840	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS06845	COG5006	permease, DMT superfamily
FYA37_RS06870	COG2264	protein methyltransferase activity
FYA37_RS06905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA37_RS06910	COG0746	molybdenum cofactor guanylyltransferase activity
FYA37_RS06915	COG0303	'Molybdopterin
FYA37_RS06920	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA37_RS06925	COG0314	molybdopterin synthase activity
FYA37_RS06935	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA37_RS06940	COG0412	Dienelactone hydrolase
FYA37_RS06950	COG0678	peroxiredoxin activity
FYA37_RS06965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA37_RS06975	COG0542	response to heat
FYA37_RS06990	COG1477	protein flavinylation
FYA37_RS07015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FYA37_RS07020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA37_RS07020	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FYA37_RS07025	COG1562	ergosterol biosynthetic process
FYA37_RS07030	COG1562	ergosterol biosynthetic process
FYA37_RS07035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA37_RS07075	COG0254	rRNA binding
FYA37_RS07080	COG3483	tryptophan 2,3-dioxygenase activity
FYA37_RS07085	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FYA37_RS07090	COG2003	Belongs to the UPF0758 family
FYA37_RS07100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FYA37_RS07105	COG0625	glutathione transferase activity
FYA37_RS07125	COG0523	cobalamin synthesis protein
FYA37_RS07135	COG0583	DNA-binding transcription factor activity
FYA37_RS07145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA37_RS07150	COG1187	pseudouridine synthase activity
FYA37_RS07155	COG0779	Required for maturation of 30S ribosomal subunits
FYA37_RS07160	COG0195	Participates in both transcription termination and antitermination
FYA37_RS07160	COG2251	uridine kinase activity
FYA37_RS07165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FYA37_RS07170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FYA37_RS07175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA37_RS07180	COG1217	gtp-binding protein TYPA
FYA37_RS07195	COG1802	Transcriptional regulator
FYA37_RS07205	COG1024	Enoyl-CoA hydratase
FYA37_RS07210	COG0318	PFAM AMP-dependent synthetase and ligase
FYA37_RS07220	COG2032	superoxide dismutase activity
FYA37_RS07235	COG4120	Belongs to the binding-protein-dependent transport system permease family
FYA37_RS07240	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA37_RS07245	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA37_RS07250	COG4149	molybdate abc transporter
FYA37_RS07280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS07285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS07290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA37_RS07300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA37_RS07305	COG0736	holo-[acyl-carrier-protein] synthase activity
FYA37_RS07310	COG1472	Belongs to the glycosyl hydrolase 3 family
FYA37_RS07315	COG0322	excinuclease ABC activity
FYA37_RS07320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA37_RS07330	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA37_RS07330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FYA37_RS07335	COG2224	Isocitrate lyase
FYA37_RS07340	COG1846	Transcriptional regulator
FYA37_RS07345	COG1764	response to oxidative stress
FYA37_RS07350	COG1131	(ABC) transporter
FYA37_RS07360	COG0628	permease
FYA37_RS07385	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FYA37_RS07395	COG2814	Major facilitator Superfamily
FYA37_RS07415	COG3015	lipoprotein NlpE involved in copper resistance
FYA37_RS07425	COG3530	Putative quorum-sensing-regulated virulence factor
FYA37_RS07440	COG0494	nUDIX hydrolase
FYA37_RS07450	COG0697	spore germination
FYA37_RS07455	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FYA37_RS07480	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FYA37_RS07485	COG1702	phosphate starvation-inducible protein PhoH
FYA37_RS07490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FYA37_RS07495	COG4535	Mg2 and Co2 transporter CorC
FYA37_RS07500	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FYA37_RS07505	COG0667	Aldo Keto reductase
FYA37_RS07525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA37_RS07530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA37_RS07535	COG1862	Preprotein translocase
FYA37_RS07540	COG0343	queuine tRNA-ribosyltransferase activity
FYA37_RS07545	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FYA37_RS07550	COG2027	D-alanyl-D-alanine carboxypeptidase
FYA37_RS07555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FYA37_RS07560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA37_RS07560	COG1648	precorrin-2 dehydrogenase activity
FYA37_RS07570	COG4575	ribosome binding
FYA37_RS07595	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FYA37_RS07600	COG0741	lytic transglycosylase activity
FYA37_RS07605	COG0436	Aminotransferase
FYA37_RS07615	COG0280	phosphate acetyltransferase
FYA37_RS07615	COG0281	malic enzyme
FYA37_RS07630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA37_RS07635	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA37_RS07640	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA37_RS07645	COG0126	phosphoglycerate kinase activity
FYA37_RS07660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA37_RS07675	COG0625	glutathione transferase activity
FYA37_RS07695	COG0789	Transcriptional regulator
FYA37_RS07710	COG0306	phosphate transporter
FYA37_RS07715	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA37_RS07725	COG0739	heme binding
FYA37_RS07735	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FYA37_RS07775	COG0456	acetyltransferase
FYA37_RS07780	COG1301	dicarboxylic acid transport
FYA37_RS07790	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FYA37_RS07795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FYA37_RS07800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA37_RS07805	COG0009	L-threonylcarbamoyladenylate synthase
FYA37_RS07815	COG4771	TonB-dependent receptor
FYA37_RS07845	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS07850	COG0028	Belongs to the TPP enzyme family
FYA37_RS07855	COG0583	DNA-binding transcription factor activity
FYA37_RS07860	COG4974	Belongs to the 'phage' integrase family
FYA37_RS07865	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA37_RS07870	COG1686	Belongs to the peptidase S11 family
FYA37_RS07900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA37_RS07905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FYA37_RS07910	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA37_RS07930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA37_RS07935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA37_RS07940	COG0505	Belongs to the CarA family
FYA37_RS07945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FYA37_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS07960	COG0406	alpha-ribazole phosphatase activity
FYA37_RS07990	COG2233	PERMEase
FYA37_RS07995	COG3620	sequence-specific DNA binding
FYA37_RS08005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA37_RS08015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FYA37_RS08020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA37_RS08030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA37_RS08045	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FYA37_RS08065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA37_RS08125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA37_RS08155	COG0540	Belongs to the ATCase OTCase family
FYA37_RS08160	COG2974	May be involved in recombination
FYA37_RS08185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FYA37_RS08190	COG2137	regulation of response to DNA damage stimulus
FYA37_RS08200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FYA37_RS08220	COG0045	succinate-CoA ligase (ADP-forming) activity
FYA37_RS08225	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FYA37_RS08230	COG0861	Integral membrane protein TerC family
FYA37_RS08235	COG0861	Integral membrane protein TerC family
FYA37_RS08240	COG0181	hydroxymethylbilane synthase activity
FYA37_RS08280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA37_RS08325	COG1450	Type ii and iii secretion system protein
FYA37_RS08375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA37_RS08385	COG1295	ribonuclease BN
FYA37_RS08395	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA37_RS08415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FYA37_RS08420	COG0501	Belongs to the peptidase M48B family
FYA37_RS08425	COG2197	response regulator
FYA37_RS08450	COG0066	3-isopropylmalate dehydratase activity
FYA37_RS08460	COG0473	3-isopropylmalate dehydrogenase activity
FYA37_RS08465	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FYA37_RS08475	COG0101	tRNA pseudouridine synthase activity
FYA37_RS08480	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FYA37_RS08485	COG0135	phosphoribosylanthranilate isomerase activity
FYA37_RS08505	COG2801	Transposase and inactivated derivatives
FYA37_RS08510	COG2801	Transposase and inactivated derivatives
FYA37_RS08550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA37_RS08555	COG2197	response regulator
FYA37_RS08560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYA37_RS08565	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FYA37_RS08580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA37_RS08585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA37_RS08595	COG1764	response to oxidative stress
FYA37_RS08610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS08615	COG0765	amino acid transport
FYA37_RS08620	COG0765	amino acid transport
FYA37_RS08630	COG0756	dUTP diphosphatase activity
FYA37_RS08660	COG1522	sequence-specific DNA binding
FYA37_RS08680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA37_RS08685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FYA37_RS08690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA37_RS08695	COG0196	riboflavin kinase activity
FYA37_RS08705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA37_RS08705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA37_RS08735	COG0210	DNA helicase
FYA37_RS08740	COG4771	TonB-dependent receptor
FYA37_RS08750	COG0488	(ABC) transporter
FYA37_RS08755	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA37_RS08760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FYA37_RS08765	COG2171	N-acyltransferase activity
FYA37_RS08820	COG2801	Transposase and inactivated derivatives
FYA37_RS08860	COG2814	Major facilitator Superfamily
FYA37_RS08885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA37_RS08890	COG2900	Belongs to the SlyX family
FYA37_RS08905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA37_RS08925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA37_RS08950	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FYA37_RS08955	COG0583	DNA-binding transcription factor activity
FYA37_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS08970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA37_RS08975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA37_RS08990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA37_RS08995	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA37_RS09000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FYA37_RS09010	COG4566	intracellular signal transduction
FYA37_RS09015	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FYA37_RS09035	COG1999	signal sequence binding
FYA37_RS09055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS09060	COG0583	DNA-binding transcription factor activity
FYA37_RS09065	COG1187	pseudouridine synthase activity
FYA37_RS09070	COG3161	chorismate lyase activity
FYA37_RS09085	COG1280	lysine exporter protein (LysE YggA)
FYA37_RS09125	COG1129	ABC transporter
FYA37_RS09140	COG0583	DNA-binding transcription factor activity
FYA37_RS09170	COG1185	polyribonucleotide nucleotidyltransferase activity
FYA37_RS09175	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FYA37_RS09190	COG1183	phosphatidylcholine synthase activity
FYA37_RS09200	COG0440	acetolactate synthase activity
FYA37_RS09205	COG0028	Belongs to the TPP enzyme family
FYA37_RS09230	COG3022	response to hydroperoxide
FYA37_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS09255	COG3486	L-lysine 6-monooxygenase (NADPH) activity
FYA37_RS09285	COG2814	Major facilitator Superfamily
FYA37_RS09315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA37_RS09350	COG2733	membrane
FYA37_RS09375	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FYA37_RS09395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS09400	COG1129	ABC transporter
FYA37_RS09400	COG0842	Transport permease protein
FYA37_RS09405	COG0842	Transport permease protein
FYA37_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS09425	COG2259	Doxx family
FYA37_RS09455	COG0415	Belongs to the DNA photolyase family
FYA37_RS09475	COG0386	Belongs to the glutathione peroxidase family
FYA37_RS09490	COG0095	Lipoate-protein ligase
FYA37_RS09500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA37_RS09510	COG0010	Belongs to the arginase family
FYA37_RS09520	COG0765	amino acid transport
FYA37_RS09525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS09540	COG0084	hydrolase, TatD family'
FYA37_RS09550	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FYA37_RS09555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA37_RS09565	COG2175	clavaminate synthase activity
FYA37_RS09570	COG0583	DNA-binding transcription factor activity
FYA37_RS09595	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FYA37_RS09605	COG2914	Belongs to the UPF0125 (RnfH) family
FYA37_RS09615	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FYA37_RS09650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA37_RS09650	COG0519	Catalyzes the synthesis of GMP from XMP
FYA37_RS09660	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FYA37_RS09670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA37_RS09675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA37_RS09680	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA37_RS09690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FYA37_RS09695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA37_RS09705	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA37_RS09710	COG0750	zinc metalloprotease
FYA37_RS09715	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FYA37_RS09725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA37_RS09730	COG0233	cytoplasmic translational termination
FYA37_RS09735	COG0528	UMP kinase activity
FYA37_RS09740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FYA37_RS09745	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA37_RS09750	COG0024	Methionine aminopeptidase
FYA37_RS09755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FYA37_RS09775	COG1286	toxin biosynthetic process
FYA37_RS09785	COG0285	dihydrofolate synthase activity
FYA37_RS09795	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS09800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS09840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FYA37_RS09850	COG1677	Flagellar hook-basal body complex protein FliE
FYA37_RS09860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA37_RS09865	COG1317	bacterial-type flagellum organization
FYA37_RS09885	COG1580	Controls the rotational direction of flagella during chemotaxis
FYA37_RS09895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FYA37_RS09920	COG0840	transmembrane signaling receptor activity
FYA37_RS09925	COG0840	transmembrane signaling receptor activity
FYA37_RS09945	COG1191	sigma factor activity
FYA37_RS09980	COG2199	diguanylate cyclase activity
FYA37_RS09980	COG2203	Gaf domain
FYA37_RS09990	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA37_RS10015	COG1126	abc transporter atp-binding protein
FYA37_RS10020	COG0765	amino acid transport
FYA37_RS10025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS10070	COG2200	EAL domain
FYA37_RS10090	COG1253	flavin adenine dinucleotide binding
FYA37_RS10095	COG5001	Diguanylate cyclase
FYA37_RS10095	COG4251	negative regulation of phosphorylation
FYA37_RS10095	COG3706	GGDEF domain
FYA37_RS10095	COG2203	Gaf domain
FYA37_RS10100	COG2197	response regulator
FYA37_RS10105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS10105	COG2205	protein histidine kinase activity
FYA37_RS10130	COG0076	glutamate decarboxylase activity
FYA37_RS10135	COG2985	domain, Protein
FYA37_RS10140	COG3189	MarR family transcriptional regulator
FYA37_RS10150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA37_RS10160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA37_RS10160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA37_RS10170	COG0028	Belongs to the TPP enzyme family
FYA37_RS10180	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS10190	COG0688	phosphatidylethanolamine metabolic process
FYA37_RS10195	COG1304	FMN binding
FYA37_RS10200	COG1464	Belongs to the NlpA lipoprotein family
FYA37_RS10220	COG0697	spore germination
FYA37_RS10225	COG2133	pyrroloquinoline quinone binding
FYA37_RS10230	COG0625	glutathione transferase activity
FYA37_RS10240	COG1794	racemase activity, acting on amino acids and derivatives
FYA37_RS10260	COG0559	Belongs to the binding-protein-dependent transport system permease family
FYA37_RS10270	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FYA37_RS10285	COG1175	transmembrane transport
FYA37_RS10290	COG0395	ABC-type sugar transport system, permease component
FYA37_RS10295	COG3842	ATPase activity
FYA37_RS10320	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA37_RS10335	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS10360	COG0463	Glycosyl transferase, family 2
FYA37_RS10375	COG0783	Belongs to the Dps family
FYA37_RS10380	COG0583	DNA-binding transcription factor activity
FYA37_RS10385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA37_RS10415	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA37_RS10425	COG3842	ATPase activity
FYA37_RS10430	COG1741	Belongs to the pirin family
FYA37_RS10435	COG1741	Belongs to the pirin family
FYA37_RS10440	COG0583	DNA-binding transcription factor activity
FYA37_RS10455	COG0174	glutamine synthetase
FYA37_RS10460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA37_RS10465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FYA37_RS10475	COG0840	transmembrane signaling receptor activity
FYA37_RS10485	COG0583	DNA-binding transcription factor activity
FYA37_RS10490	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS10495	COG2079	MmgE PrpD family protein
FYA37_RS10505	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FYA37_RS10510	COG1561	YicC-like family, N-terminal region
FYA37_RS10520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA37_RS10525	COG0791	NLP P60 protein
FYA37_RS10530	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS10535	COG0194	GDP metabolic process
FYA37_RS10540	COG1758	RNA polymerase activity
FYA37_RS10545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA37_RS10550	COG1126	abc transporter atp-binding protein
FYA37_RS10555	COG0765	amino acid transport
FYA37_RS10560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS10570	COG2831	hemolysin activation secretion protein
FYA37_RS10580	COG3188	usher protein
FYA37_RS10585	COG3121	Chaperone
FYA37_RS10600	COG3210	domain, Protein
FYA37_RS10600	COG3064	Membrane
FYA37_RS10600	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
FYA37_RS10610	COG4181	ATPase activity
FYA37_RS10620	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA37_RS10625	COG0584	glycerophosphoryl diester phosphodiesterase
FYA37_RS10630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA37_RS10640	COG0678	peroxiredoxin activity
FYA37_RS10640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA37_RS10650	COG2217	Heavy metal translocating P-type atpase
FYA37_RS10655	COG0789	Transcriptional regulator
FYA37_RS10660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FYA37_RS10695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA37_RS10705	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FYA37_RS10730	COG0583	DNA-binding transcription factor activity
FYA37_RS10735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FYA37_RS10740	COG2252	PERMEase
FYA37_RS10745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA37_RS10750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FYA37_RS10785	COG0488	(ABC) transporter
FYA37_RS10790	COG1619	proteins homologs of microcin C7 resistance protein MccF
FYA37_RS10795	COG0590	tRNA wobble adenosine to inosine editing
FYA37_RS10810	COG1320	monovalent cation:proton antiporter activity
FYA37_RS10815	COG2212	antiporter activity
FYA37_RS10820	COG1863	multisubunit Na H antiporter MnhE subunit
FYA37_RS10825	COG0651	ATP synthesis coupled electron transport
FYA37_RS10830	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA37_RS10835	COG2111	Na H antiporter
FYA37_RS10835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA37_RS10840	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS10865	COG0420	3'-5' exonuclease activity
FYA37_RS10900	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA37_RS10910	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FYA37_RS10920	COG2130	NADP-dependent
FYA37_RS10925	COG1309	transcriptional regulator
FYA37_RS10935	COG1131	(ABC) transporter
FYA37_RS10940	COG0842	Transport permease protein
FYA37_RS10950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA37_RS10985	COG0602	queuosine metabolic process
FYA37_RS10990	COG0720	synthase
FYA37_RS11025	COG0587	DNA-directed DNA polymerase activity
FYA37_RS11035	COG0390	transport system, permease component
FYA37_RS11040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA37_RS11045	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FYA37_RS11100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA37_RS11125	COG5507	3-demethylubiquinone-9 3-methyltransferase
FYA37_RS11160	COG1396	sequence-specific DNA binding
FYA37_RS11185	COG0583	DNA-binding transcription factor activity
FYA37_RS11190	COG2814	Major facilitator Superfamily
FYA37_RS11215	COG2807	transmembrane transport
FYA37_RS11220	COG2207	Transcriptional regulator
FYA37_RS11225	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA37_RS11230	COG2814	Major facilitator Superfamily
FYA37_RS11245	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS11280	COG0583	DNA-binding transcription factor activity
FYA37_RS11305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA37_RS11330	COG0384	phenazine biosynthesis protein PhzF
FYA37_RS11335	COG1733	regulation of RNA biosynthetic process
FYA37_RS11370	COG3177	Filamentation induced by cAMP protein fic
FYA37_RS11380	COG0519	Catalyzes the synthesis of GMP from XMP
FYA37_RS11380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA37_RS11395	COG1695	Transcriptional regulator
FYA37_RS11410	COG2072	flavoprotein involved in K transport
FYA37_RS11415	COG0601	transmembrane transport
FYA37_RS11435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS11445	COG4608	Belongs to the ABC transporter superfamily
FYA37_RS11450	COG0747	negative chemotaxis
FYA37_RS11490	COG0047	phosphoribosylformylglycinamidine synthase activity
FYA37_RS11490	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYA37_RS11495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA37_RS11515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FYA37_RS11515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FYA37_RS11520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FYA37_RS11530	COG0613	PHP domain protein
FYA37_RS11590	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS11600	COG0583	DNA-binding transcription factor activity
FYA37_RS11620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FYA37_RS11630	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS11640	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS11670	COG1595	DNA-templated transcription, initiation
FYA37_RS11675	COG3712	iron ion homeostasis
FYA37_RS11685	COG0084	hydrolase, TatD family'
FYA37_RS11690	COG1136	(ABC) transporter
FYA37_RS11705	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYA37_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS11720	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FYA37_RS11730	COG1803	Methylglyoxal synthase
FYA37_RS11750	COG2801	Transposase and inactivated derivatives
FYA37_RS11755	COG2801	Transposase and inactivated derivatives
FYA37_RS11780	COG2975	iron-sulfur cluster assembly
FYA37_RS11785	COG0633	Ferredoxin
FYA37_RS11790	COG0443	Heat shock 70 kDa protein
FYA37_RS11795	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FYA37_RS11800	COG0316	Belongs to the HesB IscA family
FYA37_RS11805	COG0822	iron-sulfur transferase activity
FYA37_RS11810	COG1104	cysteine desulfurase activity
FYA37_RS11820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA37_RS11825	COG0556	nucleotide-excision repair
FYA37_RS11840	COG0583	DNA-binding transcription factor activity
FYA37_RS11860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA37_RS11900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA37_RS11915	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FYA37_RS11925	COG0740	serine-type endopeptidase activity
FYA37_RS11930	COG0544	peptidyl-prolyl cis-trans isomerase activity
FYA37_RS11975	COG2801	Transposase and inactivated derivatives
FYA37_RS11985	COG1278	Cold shock
FYA37_RS12015	COG2433	Pfam Transposase IS66
FYA37_RS12075	COG1530	ribonuclease E activity
FYA37_RS12110	COG1846	Transcriptional regulator
FYA37_RS12120	COG1566	PFAM secretion protein HlyD family protein
FYA37_RS12125	COG2814	Major facilitator Superfamily
FYA37_RS12130	COG0473	3-isopropylmalate dehydrogenase activity
FYA37_RS12150	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA37_RS12155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA37_RS12165	COG0433	COG0433 Predicted ATPase
FYA37_RS12170	COG0217	transcriptional regulatory protein
FYA37_RS12175	COG0151	Belongs to the GarS family
FYA37_RS12185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FYA37_RS12190	COG0799	negative regulation of ribosome biogenesis
FYA37_RS12195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FYA37_RS12200	COG0424	maF-like protein
FYA37_RS12210	COG4191	Histidine kinase
FYA37_RS12215	COG2204	response regulator
FYA37_RS12240	COG0500	methyltransferase
FYA37_RS12255	COG0803	Belongs to the bacterial solute-binding protein 9 family
FYA37_RS12260	COG1121	(ABC) transporter
FYA37_RS12265	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA37_RS12270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA37_RS12285	COG4993	Dehydrogenase
FYA37_RS12295	COG4772	TonB-dependent receptor
FYA37_RS12300	COG2814	Major facilitator Superfamily
FYA37_RS12320	COG0037	tRNA processing
FYA37_RS12325	COG0825	malonyl-CoA metabolic process
FYA37_RS12335	COG0215	cysteine-tRNA ligase activity
FYA37_RS12345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA37_RS12350	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA37_RS12355	COG1968	undecaprenyl-diphosphatase activity
FYA37_RS12360	COG1253	flavin adenine dinucleotide binding
FYA37_RS12365	COG0483	inositol monophosphate 1-phosphatase activity
FYA37_RS12385	COG0668	transmembrane transport
FYA37_RS12410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA37_RS12420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA37_RS12435	COG1802	Transcriptional regulator
FYA37_RS12455	COG3360	Dodecin
FYA37_RS12475	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FYA37_RS12480	COG2850	peptidyl-arginine hydroxylation
FYA37_RS12490	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FYA37_RS12495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA37_RS12500	COG1994	Peptidase M50
FYA37_RS12505	COG0009	L-threonylcarbamoyladenylate synthase
FYA37_RS12510	COG2321	neutral zinc metallopeptidase
FYA37_RS12530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA37_RS12540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA37_RS12550	COG2271	Major facilitator Superfamily
FYA37_RS12625	COG2202	Pas domain
FYA37_RS12625	COG2200	EAL domain
FYA37_RS12625	COG2199	diguanylate cyclase activity
FYA37_RS12630	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
FYA37_RS12650	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS12655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS12660	COG2186	Transcriptional regulator
FYA37_RS12685	COG1595	DNA-templated transcription, initiation
FYA37_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS12735	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA37_RS12755	COG4604	ABC transporter, ATP-binding protein
FYA37_RS12760	COG4605	iron ion homeostasis
FYA37_RS12765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA37_RS12770	COG4607	ABC-type enterochelin transport system periplasmic component
FYA37_RS12775	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS12785	COG0149	triose-phosphate isomerase activity
FYA37_RS12790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA37_RS12790	COG3321	synthase
FYA37_RS12790	COG4221	oxidoreductase activity
FYA37_RS12790	COG0604	alcohol dehydrogenase
FYA37_RS12820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA37_RS12820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA37_RS12825	COG0668	transmembrane transport
FYA37_RS12830	COG0165	Argininosuccinate lyase
FYA37_RS12840	COG0789	Transcriptional regulator
FYA37_RS12850	COG0501	Belongs to the peptidase M48B family
FYA37_RS12855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA37_RS12880	COG1024	Enoyl-CoA hydratase
FYA37_RS12885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS12905	COG3468	outer membrane autotransporter barrel domain protein
FYA37_RS12950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FYA37_RS12955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA37_RS12960	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA37_RS12965	COG1674	ftsk spoiiie
FYA37_RS12970	COG0492	ferredoxin-NADP+ reductase activity
FYA37_RS12975	COG1193	negative regulation of DNA recombination
FYA37_RS12990	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA37_RS13005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA37_RS13010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA37_RS13015	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FYA37_RS13025	COG0745	RESPONSE REGULATOR receiver
FYA37_RS13060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA37_RS13080	COG0612	Peptidase, M16
FYA37_RS13090	COG0443	Heat shock 70 kDa protein
FYA37_RS13100	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FYA37_RS13110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FYA37_RS13115	COG1420	regulation of RNA biosynthetic process
FYA37_RS13120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA37_RS13125	COG0497	DNA recombination
FYA37_RS13155	COG0735	belongs to the Fur family
FYA37_RS13160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA37_RS13205	COG2828	Protein conserved in bacteria
FYA37_RS13210	COG1280	lysine exporter protein (LysE YggA)
FYA37_RS13215	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS13235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FYA37_RS13240	COG1802	Transcriptional regulator
FYA37_RS13245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA37_RS13250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA37_RS13255	COG1335	isochorismatase
FYA37_RS13260	COG0523	cobalamin synthesis protein
FYA37_RS13290	COG0583	DNA-binding transcription factor activity
FYA37_RS13300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA37_RS13305	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FYA37_RS13310	COG0167	dihydroorotate dehydrogenase activity
FYA37_RS13355	COG1414	Transcriptional regulator
FYA37_RS13375	COG0513	Belongs to the DEAD box helicase family
FYA37_RS13400	COG0429	hydrolase of the alpha beta-hydrolase fold
FYA37_RS13445	COG0006	proline dipeptidase activity
FYA37_RS13455	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA37_RS13485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FYA37_RS13490	COG0632	four-way junction helicase activity
FYA37_RS13505	COG2255	four-way junction helicase activity
FYA37_RS13510	COG0514	ATP-dependent DNA helicase (RecQ)
FYA37_RS13530	COG1294	oxidase, subunit
FYA37_RS13540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA37_RS13545	COG0850	regulation of cytokinetic process
FYA37_RS13550	COG2894	cell division
FYA37_RS13555	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA37_RS13580	COG0488	(ABC) transporter
FYA37_RS13595	COG4608	Belongs to the ABC transporter superfamily
FYA37_RS13600	COG0444	Belongs to the ABC transporter superfamily
FYA37_RS13605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS13620	COG1215	transferase activity, transferring glycosyl groups
FYA37_RS13625	COG0583	DNA-binding transcription factor activity
FYA37_RS13630	COG1368	sulfuric ester hydrolase activity
FYA37_RS13635	COG1686	Belongs to the peptidase S11 family
FYA37_RS13645	COG1280	lysine exporter protein (LysE YggA)
FYA37_RS13655	COG1064	alcohol dehydrogenase
FYA37_RS13660	COG4191	Histidine kinase
FYA37_RS13665	COG4566	intracellular signal transduction
FYA37_RS13675	COG1802	Transcriptional regulator
FYA37_RS13700	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS13705	COG0513	Belongs to the DEAD box helicase family
FYA37_RS13710	COG0668	transmembrane transport
FYA37_RS13725	COG1595	DNA-templated transcription, initiation
FYA37_RS13765	COG0583	DNA-binding transcription factor activity
FYA37_RS13770	COG0531	amino acid
FYA37_RS13775	COG1982	Orn Lys Arg decarboxylase major
FYA37_RS13800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FYA37_RS13805	COG0459	protein refolding
FYA37_RS13815	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FYA37_RS13820	COG1252	NADH dehydrogenase
FYA37_RS13825	COG0284	orotidine-5'-phosphate decarboxylase activity
FYA37_RS13835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA37_RS13845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA37_RS13850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FYA37_RS13880	COG1595	DNA-templated transcription, initiation
FYA37_RS13890	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FYA37_RS13895	COG3639	organic phosphonate transmembrane transporter activity
FYA37_RS13900	COG3639	organic phosphonate transmembrane transporter activity
FYA37_RS13915	COG0742	ribosomal rna small subunit methyltransferase
FYA37_RS13920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FYA37_RS13925	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA37_RS13930	COG3135	benzoate transporter
FYA37_RS13950	COG4774	siderophore transport
FYA37_RS13975	COG1024	Enoyl-CoA hydratase
FYA37_RS13980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA37_RS13985	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS13995	COG0318	PFAM AMP-dependent synthetase and ligase
FYA37_RS14000	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS14010	COG0583	DNA-binding transcription factor activity
FYA37_RS14035	COG0277	FAD linked oxidase domain protein
FYA37_RS14055	COG1802	Transcriptional regulator
FYA37_RS14070	COG2271	Major facilitator Superfamily
FYA37_RS14080	COG0583	DNA-binding transcription factor activity
FYA37_RS14105	COG0012	GTP binding
FYA37_RS14115	COG0193	aminoacyl-tRNA hydrolase activity
FYA37_RS14120	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FYA37_RS14125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA37_RS14135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FYA37_RS14150	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FYA37_RS14175	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FYA37_RS14185	COG1368	sulfuric ester hydrolase activity
FYA37_RS14190	COG2186	Transcriptional regulator
FYA37_RS14200	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS14215	COG0277	FAD linked oxidase domain protein
FYA37_RS14230	COG0166	Belongs to the GPI family
FYA37_RS14235	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS14240	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS14255	COG0438	transferase activity, transferring glycosyl groups
FYA37_RS14270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA37_RS14275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FYA37_RS14290	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FYA37_RS14300	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FYA37_RS14310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA37_RS14315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA37_RS14330	COG0747	negative chemotaxis
FYA37_RS14340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS14345	COG4172	Belongs to the ABC transporter superfamily
FYA37_RS14370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA37_RS14370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FYA37_RS14375	COG0509	glycine decarboxylation via glycine cleavage system
FYA37_RS14380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FYA37_RS14385	COG2081	HI0933 family
FYA37_RS14400	COG0456	acetyltransferase
FYA37_RS14405	COG0717	Belongs to the dCTP deaminase family
FYA37_RS14420	COG0489	protein tyrosine kinase activity
FYA37_RS14430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA37_RS14430	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA37_RS14455	COG3539	Fimbrial protein
FYA37_RS14470	COG0745	RESPONSE REGULATOR receiver
FYA37_RS14500	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FYA37_RS14515	COG2084	Dehydrogenase
FYA37_RS14520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA37_RS14545	COG3842	ATPase activity
FYA37_RS14550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FYA37_RS14555	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS14565	COG0583	DNA-binding transcription factor activity
FYA37_RS14575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS14580	COG1024	Enoyl-CoA hydratase
FYA37_RS14600	COG0583	DNA-binding transcription factor activity
FYA37_RS14605	COG1408	metallophosphoesterase
FYA37_RS14610	COG0625	glutathione transferase activity
FYA37_RS14645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA37_RS14645	COG0426	domain, Protein
FYA37_RS14650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA37_RS14655	COG0583	DNA-binding transcription factor activity
FYA37_RS14665	COG1024	Enoyl-CoA hydratase
FYA37_RS14675	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS14685	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS14705	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS14710	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS14720	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS14760	COG0583	DNA-binding transcription factor activity
FYA37_RS14765	COG1960	acyl-CoA dehydrogenase activity
FYA37_RS14770	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS14775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS14780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA37_RS14805	COG0560	Phosphoserine phosphatase
FYA37_RS14810	COG0583	DNA-binding transcription factor activity
FYA37_RS14820	COG3842	ATPase activity
FYA37_RS14835	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA37_RS14855	COG0625	glutathione transferase activity
FYA37_RS14895	COG4336	lyase activity
FYA37_RS14905	COG0326	Molecular chaperone. Has ATPase activity
FYA37_RS14910	COG2233	PERMEase
FYA37_RS14950	COG2818	Glycosylase
FYA37_RS14955	COG0727	PFAM Uncharacterised protein family (UPF0153)
FYA37_RS14980	COG0402	S-adenosylhomocysteine deaminase activity
FYA37_RS14995	COG0156	8-amino-7-oxononanoate synthase activity
FYA37_RS15000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FYA37_RS15050	COG1464	Belongs to the NlpA lipoprotein family
FYA37_RS15055	COG2011	ABC-type metal ion transport system permease component
FYA37_RS15060	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA37_RS15065	COG1501	Belongs to the glycosyl hydrolase 31 family
FYA37_RS15070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA37_RS15070	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA37_RS15075	COG0483	inositol monophosphate 1-phosphatase activity
FYA37_RS15080	COG0318	PFAM AMP-dependent synthetase and ligase
FYA37_RS15085	COG1473	amidohydrolase
FYA37_RS15090	COG0583	DNA-binding transcription factor activity
FYA37_RS15095	COG2855	membrane
FYA37_RS15105	COG2239	Acts as a magnesium transporter
FYA37_RS15120	COG1522	sequence-specific DNA binding
FYA37_RS15155	COG0330	HflC and HflK could
FYA37_RS15160	COG0330	HflC and HflK could
FYA37_RS15165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA37_RS15170	COG1923	regulation of RNA biosynthetic process
FYA37_RS15180	COG1160	GTP binding
FYA37_RS15185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA37_RS15190	COG2976	Protein conserved in bacteria
FYA37_RS15195	COG0124	histidyl-tRNA synthetase
FYA37_RS15210	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA37_RS15215	COG0105	UTP biosynthetic process
FYA37_RS15220	COG0525	valine-tRNA ligase activity
FYA37_RS15230	COG0336	Belongs to the RNA methyltransferase TrmD family
FYA37_RS15235	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA37_RS15240	COG0228	four-way junction DNA binding
FYA37_RS15245	COG0425	Belongs to the sulfur carrier protein TusA family
FYA37_RS15250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FYA37_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA37_RS15320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA37_RS15320	COG0543	2 iron, 2 sulfur cluster binding
FYA37_RS15325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FYA37_RS15330	COG2076	Multidrug Resistance protein
FYA37_RS15335	COG0633	Ferredoxin
FYA37_RS15335	COG3217	Mosc domain protein beta barrel domain protein
FYA37_RS15340	COG5285	phytanoyl-CoA dioxygenase
FYA37_RS15345	COG0662	Cupin 2, conserved barrel domain protein
FYA37_RS15355	COG0456	acetyltransferase
FYA37_RS15370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FYA37_RS15400	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FYA37_RS15410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA37_RS15415	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA37_RS15420	COG1760	l-serine dehydratase
FYA37_RS15425	COG1283	sodium-dependent phosphate transmembrane transporter activity
FYA37_RS15430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA37_RS15435	COG0412	Dienelactone hydrolase
FYA37_RS15440	COG0428	transporter
FYA37_RS15450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYA37_RS15460	COG1845	cytochrome c oxidase, subunit III
FYA37_RS15465	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA37_RS15475	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA37_RS15475	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FYA37_RS15500	COG1942	4-Oxalocrotonate Tautomerase
FYA37_RS15510	COG4176	ABC-type proline glycine betaine transport system permease component
FYA37_RS15530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FYA37_RS15535	COG2814	Major facilitator Superfamily
FYA37_RS15540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FYA37_RS15545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FYA37_RS15570	COG1846	Transcriptional regulator
FYA37_RS15575	COG2814	Major facilitator Superfamily
FYA37_RS15580	COG0495	leucyl-tRNA aminoacylation
FYA37_RS15595	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FYA37_RS15615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS15620	COG2274	protein secretion by the type I secretion system
FYA37_RS15665	COG0427	acetyl-CoA hydrolase
FYA37_RS15675	COG3264	Mechanosensitive ion channel
FYA37_RS15675	COG1511	domain protein
FYA37_RS15680	COG0730	response to heat
FYA37_RS15695	COG2176	DNA-directed DNA polymerase activity
FYA37_RS15715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA37_RS15720	COG3384	dioxygenase
FYA37_RS15735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FYA37_RS15805	COG4964	Belongs to the GSP D family
FYA37_RS15850	COG1846	Transcriptional regulator
FYA37_RS15885	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA37_RS15895	COG2070	2-Nitropropane dioxygenase
FYA37_RS15900	COG2070	2-Nitropropane dioxygenase
FYA37_RS15910	COG2610	gluconate transmembrane transporter activity
FYA37_RS15925	COG1408	metallophosphoesterase
FYA37_RS15930	COG0493	'glutamate synthase
FYA37_RS15930	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA37_RS15935	COG2199	diguanylate cyclase activity
FYA37_RS15940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FYA37_RS15975	COG2159	amidohydrolase
FYA37_RS15985	COG0583	DNA-binding transcription factor activity
FYA37_RS16000	COG1024	Enoyl-CoA hydratase
FYA37_RS16005	COG2186	Transcriptional regulator
FYA37_RS16010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS16020	COG0833	amino acid
FYA37_RS16030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FYA37_RS16065	COG5265	(ABC) transporter
FYA37_RS16105	COG1971	Probably functions as a manganese efflux pump
FYA37_RS16110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA37_RS16120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA37_RS16125	COG2814	Major facilitator Superfamily
FYA37_RS16150	COG4608	Belongs to the ABC transporter superfamily
FYA37_RS16170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA37_RS16180	COG3383	formate dehydrogenase (NAD+) activity
FYA37_RS16195	COG0747	negative chemotaxis
FYA37_RS16205	COG0625	glutathione transferase activity
FYA37_RS16235	COG1595	DNA-templated transcription, initiation
FYA37_RS16245	COG4774	siderophore transport
FYA37_RS16260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA37_RS16275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA37_RS16280	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FYA37_RS16305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA37_RS16310	COG1024	Enoyl-CoA hydratase
FYA37_RS16345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA37_RS16350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA37_RS16355	COG1116	anion transmembrane transporter activity
FYA37_RS16365	COG3585	molybdate ion transport
FYA37_RS16425	COG0583	DNA-binding transcription factor activity
FYA37_RS16430	COG4948	Mandelate Racemase Muconate Lactonizing
FYA37_RS16435	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS16460	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS16465	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS16500	COG4177	L-phenylalanine transmembrane transporter activity
FYA37_RS16525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA37_RS16540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA37_RS16545	COG1538	Outer membrane efflux protein
FYA37_RS16550	COG0577	efflux transmembrane transporter activity
FYA37_RS16550	COG1136	(ABC) transporter
FYA37_RS16555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA37_RS16570	COG0259	pyridoxamine-phosphate oxidase activity
FYA37_RS16575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA37_RS16580	COG0579	oxidoreductase
FYA37_RS16590	COG0405	Gamma-glutamyltransferase
FYA37_RS16600	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS16610	COG0114	fumarate hydratase activity
FYA37_RS16615	COG0802	atpase or kinase
FYA37_RS16620	COG0860	N-Acetylmuramoyl-L-alanine amidase
FYA37_RS16625	COG0586	Pfam SNARE associated Golgi protein
FYA37_RS16630	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA37_RS16635	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FYA37_RS16640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FYA37_RS16655	COG0617	tRNA 3'-terminal CCA addition
FYA37_RS16690	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FYA37_RS16700	COG1024	Enoyl-CoA hydratase
FYA37_RS16710	COG2188	Transcriptional regulator
FYA37_RS16715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FYA37_RS16730	COG0752	glycyl-tRNA synthetase alpha subunit
FYA37_RS16735	COG0751	glycine-tRNA ligase activity
FYA37_RS16740	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FYA37_RS16745	COG0204	Acyl-transferase
FYA37_RS16775	COG0242	peptide deformylase activity
FYA37_RS16785	COG0700	Nucleoside recognition
FYA37_RS16790	COG0469	pyruvate kinase activity
FYA37_RS16795	COG1929	Belongs to the glycerate kinase type-1 family
FYA37_RS16805	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA37_RS16810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA37_RS16815	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FYA37_RS16825	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA37_RS16835	COG2154	pterin-4-alpha-carbinolamine dehydratase
FYA37_RS16840	COG2885	chlorophyll binding
FYA37_RS16850	COG0667	Aldo Keto reductase
FYA37_RS16860	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS16880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA37_RS16885	COG0288	reversible hydration of carbon dioxide
FYA37_RS16905	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA37_RS16915	COG4829	muconolactone delta-isomerase
FYA37_RS16920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA37_RS16930	COG1414	Transcriptional regulator
FYA37_RS16935	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS16940	COG2031	fatty acid transporter
FYA37_RS16945	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA37_RS16955	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FYA37_RS16960	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA37_RS16975	COG0129	dihydroxy-acid dehydratase activity
FYA37_RS16980	COG1609	Transcriptional regulator
FYA37_RS17005	COG4106	trans-aconitate 2-methyltransferase activity
FYA37_RS17020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FYA37_RS17055	COG0163	prenyltransferase activity
FYA37_RS17060	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA37_RS17065	COG2890	protein-(glutamine-N5) methyltransferase activity
FYA37_RS17070	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FYA37_RS17075	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FYA37_RS17090	COG3712	iron ion homeostasis
FYA37_RS17120	COG0659	secondary active sulfate transmembrane transporter activity
FYA37_RS17140	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS17150	COG4774	siderophore transport
FYA37_RS17160	COG1595	DNA-templated transcription, initiation
FYA37_RS17175	COG0142	geranyltranstransferase activity
FYA37_RS17180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FYA37_RS17185	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FYA37_RS17190	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FYA37_RS17195	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FYA37_RS17215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA37_RS17215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA37_RS17220	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FYA37_RS17235	COG0583	DNA-binding transcription factor activity
FYA37_RS17240	COG0861	Integral membrane protein TerC family
FYA37_RS17255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FYA37_RS17260	COG0793	Belongs to the peptidase S41A family
FYA37_RS17265	COG4942	peptidase
FYA37_RS17270	COG0588	phosphoglycerate mutase activity
FYA37_RS17280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA37_RS17285	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FYA37_RS17290	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FYA37_RS17295	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS17310	COG2226	methyltransferase
FYA37_RS17315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FYA37_RS17320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA37_RS17330	COG2204	response regulator
FYA37_RS17335	COG5000	phosphorelay sensor kinase activity
FYA37_RS17345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FYA37_RS17345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FYA37_RS17380	COG2188	Transcriptional regulator
FYA37_RS17395	COG0583	DNA-binding transcription factor activity
FYA37_RS17400	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS17420	COG0546	phosphoglycolate phosphatase activity
FYA37_RS17435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FYA37_RS17440	COG0242	peptide deformylase activity
FYA37_RS17450	COG1522	sequence-specific DNA binding
FYA37_RS17455	COG2879	small protein
FYA37_RS17460	COG1966	Carbon starvation protein
FYA37_RS17490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA37_RS17495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA37_RS17500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FYA37_RS17505	COG3181	Tripartite tricarboxylate transporter family receptor
FYA37_RS17570	COG1172	Belongs to the binding-protein-dependent transport system permease family
FYA37_RS17605	COG0640	Transcriptional regulator
FYA37_RS17645	COG0735	belongs to the Fur family
FYA37_RS17650	COG2207	Transcriptional regulator
FYA37_RS17655	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA37_RS17660	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FYA37_RS17665	COG0513	Belongs to the DEAD box helicase family
FYA37_RS17690	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA37_RS17705	COG1305	Transglutaminase-like
FYA37_RS17745	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA37_RS17750	COG1950	PFAM Membrane protein of
FYA37_RS17775	COG0024	Methionine aminopeptidase
FYA37_RS17780	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FYA37_RS17790	COG1560	Kdo2-lipid A biosynthetic process
FYA37_RS17795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FYA37_RS17805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYA37_RS17840	COG0735	belongs to the Fur family
FYA37_RS17845	COG0523	cobalamin synthesis protein
FYA37_RS17860	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FYA37_RS17870	COG2096	Adenosyltransferase
FYA37_RS17875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA37_RS17880	COG0321	lipoyl(octanoyl) transferase activity
FYA37_RS17890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA37_RS17895	COG1686	Belongs to the peptidase S11 family
FYA37_RS17920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA37_RS17930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FYA37_RS17940	COG0859	PFAM glycosyl transferase family 9
FYA37_RS17975	COG0477	Major facilitator Superfamily
FYA37_RS17990	COG3568	Endonuclease Exonuclease Phosphatase
FYA37_RS17995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FYA37_RS18025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA37_RS18030	COG1956	GAF domain-containing protein
FYA37_RS18035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA37_RS18050	COG2186	Transcriptional regulator
FYA37_RS18055	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA37_RS18070	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA37_RS18110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA37_RS18115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA37_RS18120	COG1086	Polysaccharide biosynthesis protein
FYA37_RS18150	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA37_RS18160	COG1028	Short-chain dehydrogenase reductase Sdr
FYA37_RS18165	COG1012	belongs to the aldehyde dehydrogenase family
FYA37_RS18190	COG1522	sequence-specific DNA binding
FYA37_RS18195	COG3781	membrane
FYA37_RS18235	COG2200	EAL domain
FYA37_RS18245	COG0592	DNA-directed DNA polymerase activity
FYA37_RS18250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FYA37_RS18255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FYA37_RS18260	COG0594	ribonuclease P activity
FYA37_RS18265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FYA37_RS18270	COG0706	membrane insertase activity
FYA37_RS18275	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FYA37_RS18280	COG1473	amidohydrolase
FYA37_RS18285	COG4608	Belongs to the ABC transporter superfamily
FYA37_RS18290	COG0444	Belongs to the ABC transporter superfamily
FYA37_RS18295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA37_RS18300	COG0601	transmembrane transport
FYA37_RS18310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FYA37_RS18315	COG1505	serine-type exopeptidase activity
FYA37_RS18325	COG0280	phosphate acetyltransferase
FYA37_RS18325	COG0281	malic enzyme
FYA37_RS18355	COG0436	Aminotransferase
FYA37_RS18360	COG1278	Cold shock